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Multi-Stone, Gold Bracelets, Ippolita. ... (Total: 3 Items)Click the image to load the highest resolution version.
DescriptionMulti-Stone, Gold Bracelets, Ippolita
The bangles feature oval-shaped faceted blue topaz ranging in size from 9.00 x 7.00 mm to 6.00 x 4.00 mm; together with oval-shaped peridot and blue topaz cabochons ranging in size from 8.00 x 6.00 mm to 6.00 x 4.00 mm, set in 18k gold, marked Ippolita. Gross weight 42.00 grams.
Size: 7 inches
Property from the Patricia Walker Collection
Condition Report*:
Designer: Ippolita
Gem Type: Blue Topaz, Peridot
Gem Shape: Oval facetes and oval cabochon
Gem Count: 1 - 25
Overall Condition: Very Good
Notes: Oval are designed to be oval-shaped. Dark faceted blue topaz bangles have gross weight of 13.20 and 13.70 grams. Peridot and light blue topaz bangle has a gross weight of 15.00 grams.
*Heritage Auctions strongly encourages in-person inspection of items by the bidder. Statements by Heritage regarding the condition of objects are for guidance only and should not be relied upon as statements of fact, and do not constitute a representation, warranty, or assumption of liability by Heritage. All lots offered are sold "AS IS".
Fees, Shipping, and Handling Description: Miscellaneous Collectibles, Small (view shipping information)
Sales Tax information | Terms and Conditions
Bidding Guidelines and Bid Increments
Glossary of Terms
Auction Info
Buyer's Premium per Lot:
25% on the first $100,000 (minimum $14), plus 20% of any amount between $100,000 and $1,000,000, plus 12% of any amount over $1,000,000 per lot.
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HA.com receives more traffic than any other auction house website. (Source: Similarweb.com)

subset: commoncrawl


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To be honest I agree with 10-year-old Sub-Actuality.
Alas, Sub-Actuality is caught in the folly of youth!
Henry Scorpio did a good job summing this movie up.
ClosetWeevil is like a poor man's Wikipedia.
VelvetEvoker has left this image as his final offering to the world. That's right, he's dead now. Don't get too choked up about it.
Huge props to Thoogsby for getting this theme started, and to the Something Awful Forum Goons for making all these images. Props to my homeboy Splackavellie for ghostwriting some comments.
Internment Camp Queens Caught Scamming Extra Servings Of Water And Laying Around All Day In Government-Provided Housing
Trying to change history is a terrible mistake. Tearing down all of America's Hitler statues has left us confused about our nation's proud past.
open grinders falling off lap on to carpet compilation (HD)
Ben Garrison's Cartoons explained; Part 2!
History people smiling!
Photoshop Phriday showcases the tremendous image manipulation talents of the Something Awful Forum Goons. Each week they tackle a new theme, parodying movies, video games, comics, history, and anything else you can think of. If you want in on the action, join us on the Something Awful Forums!
Copyright ©2017 Rich "Lowtax" Kyanka & Something Awful LLC.


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Yubikey is a USB multi-factor authentication device for LastPass etc.
Last August I did a post on the password manager LastPass, you can read about it here. I recently purchased the Yubikey, which compliments this awesome password manager and other online websites. What does multi-factor authentication mean? Multifactor authentication (MFA) is a security system that requires…
The countdown has started to the Bowen road trip around California.
The countdown has begun! Our road trip around California starts in a few weeks time. I quite like this new theme and all the features it has built into it, the countdown being one of them. The excitement is growing day by day. We have…
Bowen rode the 2017 Prudential RideLondon FreeCycle on a Brompton bicycle.
On Saturday we joined thousands of cyclists in London for the 2017 Prudential RideLondon FreeCycle. The 8 mile route took us past many famous landmarks. Jo and I rode the route twice, once in the sun and again in the rain, which wasn't too bad…
Rediscover this day – 12th July 2011 – Camping at Bedgeberry Kent.
3 years ago to the day Jo and I were camping in Bedgeberry in Kent. It was a great weekend, although it started off somewhat damp. There is nothing worse arriving at your patch in a field in the rain and having to put up…
Bowen bought a beautiful blue black Brompton Bike…
… but bruised his balls on the bell by bouncing over a bump without braking… How is that for an alliteration? The subject was mine, the bruising his balls bit was from my colleague Adam 😉 Jo and I have been wanting new bicycles for years and…
Sandmarc offer a great set of ND Filters for my DJI Mavic Pro drone.
This is a mini review of the Sandmarc ND filters for the DJI Mavic Pro, This is my second photograph of the large quarry in Greenhithe, Kent, which sits opposite the Bluewater shopping centre. My intention was to capture the quarry, water and clouds and…
Rediscover this day – 18th June 2011 – Royal Ascot.
Google Photo has this cool feature where it shows photos from yesteryear. They pop up on my phone every other day. So I thought I would share them on my website. I have been trying to find a WordPress Plugin that can pull specific Google…
If Estrella Damm made movies, it would be called "The little things" starring Jean Reno and Laia Costa.
I have always enjoyed films starring Jean Reno. He is a great actor. So was pleasantly surprised to see a beer advert with him in it, but this was no ordinary advert. Had it been I would have skipped past it in a heart beat. I…
My DJI Mavic Pro in mid flight.
Here is my DJI Mavic Pro mid-air taken with my Samsung Galaxy S7 Edge. It looks quite menacing with the extended legs and curved propellers.
Neolithic Long Barrow Coldrum Stones near Trottiscliffe with the DJI Mavic Pro drone.
Neolithic, refers to the period of British, Irish and Manx history that spanned from circa 4000 to circa 2,500 BCE. (Source Wikipedia). My aim today was to film the neolithic long barrow known as the Coldrum Stones, with my DJI Mavic Pro drone. The stones are located…
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Apple's dead pixel policy revealed in leaked doc?
A supposed Apple internal document outlining the company's procedures for replacement of devices with dead or abnormal pixels has appeared online. According to the document, a screenshot of which was posted by the Boy Genius Report, it is Apple's policy to replace any iPod or iPhone with one or more bad pixels—referred to in the document as "pixel anomalies"—and any iPad with three or more problematic pixels. The document also lists procedures for other screen sizes ranging from 11.6 inches to 30 inches, and notes that while employees may offer a replacement unit to customers whose devices have what is considered to be an "acceptable" number of anomalies, the replacement product may have just as many if not more while still remaining within Apple's acceptable range; the customer will not receive a second replacement device under those circumstances.
Related Stories
- New details, possible photos of iPhone 8's 3D sensor emerge
- iOS 11 beta shows Control Center interface, new swipe gestures; tvOS 11 beta hints at 4K video
- iOS 11 introduces way to prevent Touch ID from opening device with fingerprint
- Report: iPhone 8 facial recognition unlocks in 'millionths of a second'
- Apple and Hollywood still discussing plans for early movie rentals
- Apple joins other companies in opposing warrantless use of location data
Hmm, on second glance, it's been updated.
So people with one or two stuck/dead pixels on their iPads are SOL? That's a bummer… I wouldn't be happy if that happened to me.
Posted by Kloan on November 3, 2010 at 6:09 PM (CDT)
I had ONE dead pixel in my iPad a couple of months ago. Took it to the Apple store and they gave me a brand new iPad on the spot. No questions, no hassles.
Posted by Kat on November 3, 2010 at 6:15 PM (CDT)
Of all the iOS devices I own, support, and otherwise see, I've never seen one with a single bad pixel, let alone many.
Same goes for all the Apple displays I have/support.
No doubt some get out, but if you want to see a product that this was awful on, look no further than the SONY PSP. May no longer be an issue, but when those came out, everyone was peaved.
Posted by sb on November 3, 2010 at 8:28 PM (CDT)
lol, the PSP was the WORST! Man, it was next to impossible to find one without at least a couple. I went through 5 or 6 before I gave up.
Posted by Kloan on November 3, 2010 at 11:22 PM (CDT)


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After much research, I cancelled my hotel in downtown Chicago for $130 and booked at this resort for the same price. What a terrible mistake. Check-in took > 2 hrs (started at around 10pm) with my toddler and infants waiting in the lobby after having driven > 6 hrs. Rooms were overbooked and they didn't have any rooms to give me. They finally cancelled somebody else's room and gave it to me. That person was in a wedding party so he/she would be very upset, I can imagine.
Property: Hilton Chicago Indian LakesAddress: 250 W Schick Rd, Bloomingdale, IL 60108-1228
Phone Number:
Location: United States > Illinois > DuPage County > Bloomingdale
Bar / Lounge Business Center with Internet Access Fitness Center with Gym / Workout Room Free High Speed Internet ( WiFi ) Free Parking Children Activities (Kid / Family Friendly) Pets Allowed ( Dog / Pet Friendly ) Restaurant Room Service Swimming Pool Wheelchair access
Ranked #2 of 3 Hotels in Bloomingdale
Price Range (Based on Average Rates): $
Hotel Class:3.5 star — Hilton Chicago Indian Lakes 3.5*
Number of rooms: 310
- Official Description (provided by the hotel):
- Rest your eyes on the lush grounds of Hilton Chicago Indian Lakes, set on 260 acres in DuPage County. Located just 28 miles from downtown Chicago and 30 minutes from O'Hare Airport, this hotel blends the comfort of hospitality with the vast landscape of the Midwest prairie. Experience the balance of Chicago-cosmopolitan and natural vistas in an iconic setting offering oversized guest rooms, scrumptious dining options, free shuttle within 3 miles and the great amenities our guests expect. ... more less
- Reservation Options:
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- Also Known As:
- Hilton Chicago/Indian Lakes Hotel Bloomingdale
- Hilton Hotel Bloomingdale
- Indian Lakes Hotel
- Indian Lake Resort Bloomingdale


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Last updated on AUGUST 08, 2017
Applies to:Oracle Agile Product Cost Management - Version 188.8.131.52 to 220.127.116.11 [Release 188.8.131.52 to 9.3.3]
Information in this document applies to any platform.
When attempting to search for Items to put on a Sourcing Project using Released Rev it returns Cancelled Revs as well.
Expected Behavior:
To only show Released Revs
What is working:
Does not show pending rev
Use Latest Rev or Advanced Search
The issue can be reproduced at will with the following steps:
1. Create an Item which has 3 released Revisions A,B and C.
2. Create two more ECOs which has revisions Rev D and E (Make sure that ECOs are not released).
3. Create Sourcing project and go to Items tab.
4. Click on Add-->Search for Items-->Released Rev. Search for the above Item.
5. Validate the Revisions in the change.history.Rev column.
6. Open the Item and go to the change order which has revision Rev D. Cancel the ECO.
7. Go to the Sourcing project -->Items tab.
8. Click on Add-->Search for Items-->Released Rev. Search for the above Item.
9. Validate the Revisions in the ChangeHistory.Rev column.
Search Palette displays Item with 4 revisions
A,B, C and D. Cancelled Revision Rev D is displayed in the search result.
Sign In with your My Oracle Support account
Don't have a My Oracle Support account? Click to get started
My Oracle Support provides customers with access to over a
Million Knowledge Articles and hundreds of Community platforms


text:
Inspection details
- Inspection:Saturday19August
- Inspection:Saturday26August
- Photos
- Video
Water Front Views!
- 3 Beds
- 1 Bath
- 2 Cars
Next Steps:Request contractAsk a question
Have you ever wanted to own your own slice of water front views but couldn't afford it?
Then look no further this property offers a great old 3 bedroom cottage on a massive 2,833m2 that backs onto the river.
The old cottage is in need of some major love and TLC as it hasn't been touched in years and offers the new buyers the chance to put their own stamp on the house and turn the whole property into a beautiful and quiet sanctuary.
- 2,833m2 block
- 3 bedroom, 1 bathroom house
- Beautiful old workers cottage
- On 3 lots on 1 title
- Plenty of space for the whole family
- Blank canvas for a renovation
- Quiet cult-a-sac
- St Edmunds College 1.6km*
- St Mary's College 1.6km*
- Ipswich Boys Grammar 1.7km*
- Bus stop 750m*
- Train station 1.5km*
• Ipswich City Mall 1.5km*
• Riverlink Shopping Centre 2.1km*
This is a great opportunity and won't last long. Properties like this come and go very fast so beat the rush and book in your private inspection. Call the agent now!!
2,833m² / 0.7 acres
2 garage spaces
Next Steps:Request contractAsk a question
- Loading...
Do you want to find out more about this suburb? Enter your details to receive a free comprehensive suburb report.


text:
Bon Iver - Blood Bank EP
While still tied to the identity of the place where it was born, Bon Iver is no longer an unplanned entity synonymous with Justin Vernon. It is an idea, a place and sentiment that has now become as international as it is timeless. As much as 'For Emma, Forever Ago' is about the cold, the 'Blood Bank' collection is about the warmth that gets you through it.
Bon Iver has grown to include more than what was available at the much-fabled Wisconsin cabin, such as piano, slide guitar, and vocoder. Both expansive and intimate, these four songs explore the darker and lighter natures of the seasons and what they signify, and offer a dynamic glimpse into the natural energy and refined craftsmanship that characterizes Justin Vernon's music.
$10 postage. Free shipping on orders over $150.
* Our Collingwood shop has large selection of vinyl with over 1,000 titles to choose from.
Ryan Adams - Gold Vinyl (2 x LP) Adams pays homage to his favorite artists...
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Ryan Adams - Jacksonville City Nights Vinyl (2 x LP) Ryan Adams and his backing...


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With a stay at Oceanview Luxury Villa 062 in Protaras (Paralimni - Protaras), you'll be minutes from Fig Tree Bay and close to Profitis Elias Church. This 4-star villa is within close proximity of Konnos Bay Beach and Pernera Beach.
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Business, Other Amenities
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Climate controlled storage units are more expensive than regular storage. So it is essential to determine whether you really need a climate controlled or an outdoor unit.
Climate Control or Conventional Storage
Creating an inventory list is one way to prevent problems after the move is completed and can be done without difficulty if a small amount of time is taken before a moving company arrives.
Moving Inventory
Another humorous guide from MoversCorp. This funny guide explains how to protect your furniture from damages.
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If you are moving yourself, you want to move efficiently and safely, avoiding costly personal injuries and damages to furniture. Every home has one or more goods that are hard to move such as big screen TVs, fridge, sofa and etc. Find out how to move your large and heavy items.
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Will.I.Am is convinced he is the fairest talent show judge on Tv because he doesn't need his pay cheque from The Voice.
The Black Eyed Peas frontman is a panellist on the British version of the Tv talent show, along with pop star Jessie J, Sir Tom Jones and The Script's Danny O'Donoghue, and is currently working on a second season.
will.i.am now reveals he doesn't need the pay cheque he receives for The Voice and only takes part in the show because he enjoys the job.
He tells Britain's Daily Mirror newspaper, "Me coming to the U.K. and doing The Voice is obviously not because of money, it's because I love it. I have that luxury of choosing things not based on what pays the most... The money I do make, I give away (to charity), so I can stand on The Voice with dignity and make my mother and grandmother proud."
The actor says he isn't "holding out for more money or doing anything like that".
The drama will be making its return to the streaming service in the near future.
Charlie Cox explains why his character Daredevil 'doesn't have time' for Jessica Jones.


text:
Grants of up to $25,000 to Clearfield County, Pennsylvania nonprofits and municipalities for projects that will develop local tourism. Projects should enhance the local economy and encourage visitors to stay within the county. Preference will be giv... GrantWatch ID#: 146447
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OR Homes for Sale
Real Estate Listings: Homes for Sale in Oregon & Washington
1510 E Jackson Street
Medford, OR 97504
Special Offer
For SaleEstimate Mortgage » Check Your Credit Score »
Type:Single Family
Year Built:1955
Sq. Feet:1,798 sq. ft.
Source ID:2980151
Listed:20 days ago
1510 E Jackson Street
Medford, OR 97504
Type:Single Family
Year Built:1955
Sq. Feet:1,798 sq. ft.
Source ID:2980151
Listed:20 days ago
Published with Southern Oregon MLS via ListHub on 07/27.
Updated 08/16.
Related listing information is deemed reliable but not guaranteed.
Marcia Ramsay-Coots
Windermere Van Vleet & Associates
Phone: 541-779-6520
Windermere Van Vleet & Associates
375 Lithia Way
Ashland, OR 97520
Phone: (541) 482-3786
Home Description
Home Description
You have to get inside this well built home that is very unique and all centered towards the back of the home.Hardwood and tile flooring throughout, gas fireplace in the living room, glass block inserted in the walls, large kitchen- dining-family room area & indoor utility room. Beautiful crown molding throughout home. Private master bedroom with second gas fireplace, nice bath, and glass doors lead to the patio & the back yard with 24' x 30' serene Koi pond w/ waterfall and nice plantings. Central gas heating and air conditioning, 1/2 bath in the hall way, two more bedrooms, and double vanities in the main bath. Double car garage, new roof, and truly an original floor plan and home.
Half Baths:1
Full Baths:2
- Patio
- Wheelchair Access
- Fireplace
- Parking
- Dishwasher
- Disposal
- Oven
- Gas System
- Forced Air
- Central Air
- + View All+ View All- View Less
Click on toggles to move map in desired direction.
This map is informational only. No representation is made or warranty given as to its accuracy or content. User assumes all risk of use.
OregonLive.com, MapQuest and their suppliers assume no responsibility for any loss or delay resulting from such use.
Real Estate Tools
Published with Southern Oregon MLS via ListHub on 07/27.
Updated 08/16.
Related listing information is deemed reliable but not guaranteed.
Medford, OR Real Estate
More Real Estate Listings for sale
- Single Family Homes & Houses in Medford, OR
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- Townhomes & Townhouses in Medford, OR
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text:
Rebecca Elliott Clayton, Centre, announces the engagement of her daughter, Amanda Dixie, to Christopher Jay Gober, Centre, son of Debra Jean Carter, Cedartown, Ga., and Ronald J. Gober, Rockmart, Ga.
The bride-elect is also the daughter of the late Mark Arnold Clayton. She is the granddaughter of Sara Woodall Elliott, Centre, and the late Robert E. Elliott and the late Mr. and Mrs. M.C. Clayton. She is a 1997 graduate of Cedar Bluff High School and a 2003 magna cum laude graduate of Jacksonville State University with a bachelor of fine arts degree with a concentration in photography. She is employed as the news director of WEIS Radio, Centre.
The prospective groom is the grandson of Jean Parker, Cedartown; Mr. and Mrs. J.L. Gober, Waco, Ga.; and the late Floy Hayes. He is also the great-grandson of Jewell Gober, Waco, and Sam Mitchell, Rockmart.
He is a 1996 graduate of Cedartown High School and attended Floyd State Community College. He is a part owner and production manager of Control Resources Inc., Rome.
The wedding is at 2 p.m. Oct. 29 in Centre First United Methodist Church. Family and friends are invited.


text:
The Faithfull FAIHSA1630S Holesaw arbor has an SDS fitting and will work with sizes 16-30 mm holesaws.
Note: Always use the correct size arbor for the saw size selected, and make sure that arbors with drive pins have these fully engaged before use.
FH Promo Catalogue 2017
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Enjoy your day in Amaya Food Gallery with your frinds and family and get 1 for Buy 1 lunch.
Amari Dhaka
47, road 41, Gulshan 2, 1212 Dhaka, Bangladesh
For query dial- 01777796444
Please Note : Once review added cannot be deleted or updated
Just one more step, you are almost there! We need to verify your identity to prevent frauds.
Invalid Phone number! Please enter correct number.
Now you can contact seller
Buy 1 Get 1
Secured payments with


text:
Question about Office Equipment & Supplies
Posted by Ryan Brown on
1, Power off the printer
2, Unplug the printer's power cord, wait 5 seconds then plug the power cord back in.
3, Hold the Power button for 6 Beeps
4, Release the Power Button
Posted on Apr 22, 2013
SOURCE: I have freestanding Series 8 dishwasher. Lately during the filling cycle water hammer is occurring. How can this be resolved
a 6ya expert can help you resolve that issue over the phone in a minute or two.
best thing about this new service is that you are never placed on hold and get to talk to real repairmen in the US.
the service is completely free and covers almost anything you can think of (from cars to computers, handyman, and even drones).
click here to download the app (for users in the US for now) and get all the help you need.
Posted on Jan 02, 2017
SOURCE: reset ink level for printer canon pixma ip1980
go to this link and download resetter......
Posted on Jan 08, 2009
SOURCE: canon printer pixma mp110
My Pixma MP110 keep on displaying "CHECK PRINTER (5800)" Please have m to solve this problem
Posted on Mar 17, 2009
SOURCE: Reset Canon printer chip
you can override ink check status and manually reset it in drivers options
Posted on Sep 22, 2009
SOURCE: How do you reset ink levels on a Canon pixma mp190 printer?
you can reset low ink error by pressing stop/reset button for 10 seconds
Posted on Oct 27, 2009
SOURCE: Canon pixma mp240 ink reset
Thats funny, cause I took the cartridges out and left the lid up, unplugged it, plugged it back in with my finger on the power button and tapped the stop/reset button twice. Put the cartridges in, pressed the color start, after some moaning a test page printed. I unplugged it again, plugged it back in and I had full ink Levels!!!
Posted on Jan 27, 2010
Tips for a great answer:
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May 02, 2009 | Canon PIXMA iP1800 InkJet Photo Printer
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text: View Full Chapter Figures Only Tables Only Videos Only Print Share Email Send Email Your Name (required) ! Example: John Doe Email Address (required) ! Please enter a valid sender email address. Example: email@example.com CC Me Recipient Email Address (required) ! Separate multiple email address with semi-colons (up to 5). Subject Subject for your email. Message (Maximum characters: 1,000) Please enter your name Please enter your email address Please enter a valid recipient email address. Example:email@example.com Submit Cancel Thank you! Your email has been sent to: The recipient(s) will receive an email message that includes a link to the selected article. Recipients may need to check their spam filters or confirm that the address is safe. Return to: Send Another Email An error has occurred sending your email(s). Please try again later or contact an administrator at firstname.lastname@example.com. Return to: Twitter Facebook Linkedin Reddit Get Citation Citation AMA Citation Kessler JA. Kessler J.A. Kessler, John A.Chapter 67. Applications of Stem Cell Biology in Clinical Medicine. In: Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, Loscalzo J. Longo D.L., Fauci A.S., Kasper D.L., Hauser S.L., Jameson J, Loscalzo J Eds. Dan L. Longo, et al.eds. Harrison's Principles of Internal Medicine, 18e New York, NY: McGraw-Hill; 2012. http://accessmedicine.mhmedical.com/content.aspx?bookid=331§ionid=40726799. Accessed August 23, 2017. MLA Citation Kessler JA. Kessler J.A. Kessler, John A.. "Chapter 67. Applications of Stem Cell Biology in Clinical Medicine." Harrison's Principles of Internal Medicine, 18e Longo DL, Fauci AS, Kasper DL, Hauser SL, Jameson J, Loscalzo J. Longo D.L., Fauci A.S., Kasper D.L., Hauser S.L., Jameson J, Loscalzo J Eds. Dan L. Longo, et al. New York, NY: McGraw-Hill, 2012, http://accessmedicine.mhmedical.com/content.aspx?bookid=331§ionid=40726799. Download citation file: RIS (Zotero) EndNote BibTex Medlars ProCite RefWorks Reference Manager © Copyright Tools Search Book Top Return Clip Chapter 67. Applications of Stem Cell Biology in Clinical Medicine John A. Kessler + Applications of Stem Cell Biology in Clinical Medicine: Introduction Print Section ++ Damage to an organ initiates a series of events that lead to the reconstruction of the damaged tissue, including proliferation, differentiation and migration of various cell types, release of cytokines and chemokines, and remodeling of the extracellular matrix. Endogenous stem and progenitor cells are among the cell populations that are involved in the injury responses. In normal steady-state conditions, an equilibrium is maintained in which endogenous stem cells intrinsic to the tissue replenish dying cells. After tissue injury, stem cells in organs, such as the liver and skin, have a remarkable ability to regenerate the organ, whereas other stem cell populations, such as those in the heart and brain, have a much more limited capability for self-repair. In rare circumstances, circulating stem cells may contribute to regenerative responses by migrating into a tissue and differentiating into organ-specific cell types. The goal of stem cell therapies is to promote cell replacement in organs that are damaged beyond their ability for self-repair. + General Strategies for Stem Cell Replacement Print Section ++ At least three different therapeutic concepts for cell replacement can be envisaged (Fig. 67-1). One therapeutic approach involves direct administration of stem cells. This may involve injection of the cells directly into the damaged organ, where they can differentiate into the desired cell type. Alternatively, stem cells may be injected systemically since they have the capacity to home in on damaged tissues by following gradients of cytokines and chemokines released by the diseased organ. A second approach involves transplantation of differentiated cells derived from stem cells. For example, pancreatic islet cells would be generated from stem cells before transplantation into diabetic patients and cardiomyocytes would be generated to treat ischemic heart disease. A third approach involves stimulation of endogenous stem cells to facilitate repair. This might be accomplished by administration of appropriate growth factors and drugs that amplify the number of endogenous stem/progenitor cells and/or direct them to differentiate into the desired cell types. Therapeutic stimulation of precursor cells is already a clinical reality in the hematopoietic system, where factors such as erythropoietin, granulocyte colony-stimulating factor (G-CSF), and granulocyte-macrophage colony-stimulating factor (GM-CSF) are used to increase production of specific blood elements. In addition to these strategies for cell replacement, a number of other approaches could involve stem cells for ex vivo or in situ generation of tissues, a process termed tissue engineering (Chap. 69). Stem cells are also excellent candidates as vehicles for cellular gene therapy (Chap. 68). Finally, transplanted stem cells may exert paracrine effects on damaged tissues without differentiating and replacing lost cells. ++Figure 67-1Graphic Jump Location+View Full Size|Favorite Figure|Download Slide (.ppt)Strategies for transplantation of stem cells. 1. Undifferentiated or partially differentiated stem cells may be injected directly into the target organ or intravenously. 2. Stem cells may be differentiated ex vivo before injection into the target organ. 3. Growth factors or other drugs may be injected to stimulate endogenous stem cell populations. ++ Stem cell transplantation is not a new concept and is already part of established medical practice. Hematopoietic stem cells (Chap. 66) are responsible for the long-term repopulation of all blood elements in recipients of bone marrow transplants, and hematopoietic stem cell transplantation is the gold standard against which other stem cell transplantation therapies will be measured. Transplantation of differentiated cells is also a clinical reality, and donated organs and tissues often are used to replace damaged tissues. However, the need for transplantable tissues and organs far outweighs the available supply, and organ transplantation has limited potential for some tissues, such as the brain. Stem cells offer the possibility of a renewable source of replacement cells for virtually all organs. + Sources of Stem Cells for Tissue Repair Print Section ++ A variety of different types of stem cells (Chap. 65) could be used in regenerative strategies, including embryonic stem (ES) cells, induced pluripotent stem cells (iPS cells), umbilical cord blood stem cells, organ-specific somatic stem cells (e.g., neural stem cells for treatment of the brain), and somatic stem cells that generate cell types specific for the target organ rather than the donor organ (e.g., bone marrow mesenchymal stem cells for cardiac repair). Each cell type has potential advantages and disadvantages, and there are a number of generic problems in developing any of these cell types into a useful and reliable clinical tool. ++ Embryonic Stem Cells ++ Embryonic stem cells have the potential to generate all the cell types in the body, and so in theory there are no restrictions on the organs that could be regenerated. They can self-renew endlessly so that a single cell line with carefully characterized traits potentially could generate almost limitless numbers of cells. In the absence of moral or ethical constraints, unused human blastocysts from fertility clinics could be used to derive new ES cell lines that are matched immunologically with potential transplant recipients. Alternatively, somatic cell nuclear transfer ("therapeutic cloning") could be used to create ES cell lines that are genetically identical to those of the patient. However, human ES cells are difficult to culture and grow slowly. Techniques for differentiating them into specific cell types are just beginning to be developed. Cells tend to develop abnormal karyotypes and other abnormalities with increased time in culture, and ES cells have the potential to form teratomas if all cells are not committed to the desired cell types before transplantation. Further, human ES cells are ethically controversial and, on these grounds, would be unacceptable to some patients and physicians despite their therapeutic potential. ++ Induced Pluripotent Stem Cells ++ The field of stem cell biology was transformed by the discovery that adult somatic cells can be converted ("reprogrammed") into pluripotent cells by overexpressing four transcription factors normally expressed in pluripotent cells (Chap. 65). These iPS cells share most properties with ES cells, although there are distinct differences in gene expression between ES and iPS cells. Viruses were used initially to insert the transcription factors into somatic cells, making them unsuitable for clinical use. However, a number of strategies have been developed to circumvent this problem, including the insertion of proteins rather than cDNAs; insertion of transposons with the programming factors, followed by their subsequent removal; and use of floxed viral constructs followed by Cre recombinase to excise the viral constructs. None of these approaches is sufficiently developed for cells to be used clinically, but appropriate techniques are likely to evolve quickly. The potential advantages of such cells are that use of somatic cells from patients would generate iPS cells genetically identical to those of the patient and that the cells do not have the same ethical constraints as ES cells. It is not clear whether the differences in gene expression between ES and iPS cells will have any impact on their potential clinical utility, and studies of both cell types will be essential to resolve this issue. ++ Umbilical Cord Stem Cells ++ Umbilical cord blood stem/progenitor cells are widely and easily available, and they appear to be associated with less graft-versus-host disease than are some other cell types, such as marrow stem cells. They have less human leukocyte antigen (HLA) restriction than adult marrow stem cells and are less likely to be contaminated with herpesvirus. However, it is unclear how many different cell types can be generated from umbilical cord blood stem cells, and methods for differentiating these cells into nonhematopoietic phenotypes are largely lacking. Further, the quantity of obtainable cells may be limiting. ++ Organ-Specific Multipotent Stem Cells ++ Organ-specific multipotent stem cells have the advantage that they are already somewhat specialized and inducement of desired cell types thus may be easier. Cells potentially could be obtained from the patient and amplified in cell culture, circumventing the problems associated with immune rejection. Stem cells are relatively easy to harvest from some tissues, such as bone marrow and blood, but difficult in the case of other tissues, such as heart and brain. However, these populations of cells are more limited in potentiality than are pluripotent ES or iPS cells, and they may be difficult to obtain in large quantities from many organs. Therefore, substantial efforts have been devoted to developing techniques for using more easily obtainable stem cell populations, such as bone marrow mesenchymal stem cells (MSCs) and adipose stem cells, for use in regenerative strategies. Tissue culture evidence suggests that these stem cell populations may be able to generate differentiated cell types unrelated to their organ source, including myocytes, chondrocytes, tendon cells, osteoblasts, cardiomyocytes, adipocytes, hepatocytes, and neurons, a process known as transdifferentiation. However, it is still unclear whether these stem cells are capable of generating differentiated cell types that integrate into organs, survive, and function after transplantation in vivo. A number of early studies of bone marrow–derived stem cells transplanted into heart, liver, and other organs suggested that the cells had differentiated into organ-specific cell types. Subsequent studies, however, revealed that the stem cells had simply fused with cells resident in the organs. Further studies will be necessary to determine whether transdifferentiation of MSCs, adipose stem cells, or other stem cell populations occurs at a high enough frequency to be useful for stem cell replacement therapy. ++ Regardless of the source of the stem cell used in regenerative strategies, there are a number of generic problems that must be overcome for the development of successful clinical applications. These problems include development of methods for reliably generating large numbers of specific cell types, minimizing the risk of tumor formation or proliferation of inappropriate cell types, ensuring the viability and function of the engrafted cells, overcoming the problems of immune rejection when autografts are not used, and facilitating revascularization of the regenerated tissue. Each organ system will also pose tissue-specific problems for stem cell therapies. + Disease-Specific Applications of Stem Cells Print Section ++ Ischemic Heart Disease and Cardiomyocyte Regeneration ++ Because of the prevalence of ischemic heart disease, extensive efforts have been devoted to the development of strategies for cell replacement of cardiomyocytes. Historically, the adult heart has been viewed as a terminally differentiated organ without the capacity for regeneration. However, recent studies have demonstrated that the heart has the ability to achieve low levels of cardiomyocyte regeneration (Chap. 224). This regeneration appears to be accomplished by cardiac stem cells resident in the heart and possibly by cells originating in the bone marrow. Cardiac stem cells might be an ideal source for therapeutic use, but techniques for isolating, characterizing, and amplifying large numbers of these cells have not been perfected. To effect myocardial repair, stem cell therapy must deliver cells either systemically or locally, and the cells must survive, engraft, and differentiate into functional cardiomyocytes that couple mechanically and electrically with the recipient myocardium. The optimal method for cell delivery is not clear, and various experimental and clinical studies have successfully employed intramyocardial, transendocardial, intravenous, and intracoronary injections. In experimental myocardial infarction, functional improvements have been achieved after transplantation of a variety of different cell types, including ES cells, bone marrow stem cells, endothelial stem cells, and adipose stem cells. Early studies suggested that each of these cell types might have the potential to engraft and generate cardiomyocytes. However, most investigators have found that the generation of new cardiomyocytes by these cells is at best a rare event and that graft survival over long periods is poor. The preponderance of evidence suggests that the beneficial effects of most experimental therapies were not derived from direct stem cell generation of cardiomyocytes but rather from indirect effects of the stem cells on resident cells. It is not clear whether this reflects the release of soluble growth factors, induction of angiogenesis, or another mechanism. The ready availability of bone marrow stem cells facilitated a series of limited clinical trials in human ischemic heart disease. A wide variety of cell delivery methods, cell types, and doses of cells have been used in the various studies, and the fate of the cells and the mechanisms by which they altered cardiac function are open questions. In aggregate, however, these studies have shown a small but measurable improvement in cardiac function and, in some cases, reduction in infarct size. The limited available evidence suggests that the beneficial effects probably reflect an indirect effect of the transplanted cells rather than genuine cell replacement. ++ Diabetes ++ Successes with islet cell and pancreas transplantation have provided proof of the concept for cell-based therapies for type 1 diabetes. However, the demand for donor pancreases far exceeds the number available, and maintenance of long-term graft survival is a problem. The search for a renewable source of stem cells capable of regenerating pancreatic islets has therefore been intensive. Pancreatic beta cell turnover occurs even in the normal pancreas, although the source of the new beta cells remains controversial. This suggests that in principle, it should be possible to develop strategies for reconstituting the beta cell population in diabetics. Attempts to devise techniques for promoting endogenous regenerative processes by using combinations of growth factors, drugs, and gene therapy have failed thus far, but this remains a potentially viable approach. A number of different cell types are candidates for use in stem cell replacement strategies, including iPS cells, ES cells, hepatic progenitor cells, pancreatic ductal progenitor cells, and bone marrow stem cells. Successful therapy will depend on the development of a source of cells that can be amplified to produce large numbers of progeny that have the ability to synthesize, store, and release insulin when it is required, primarily in response to changes in the ambient level of glucose. The proliferative capacity of the replacement cells must be tightly regulated to avoid excessive expansion of beta cell numbers with the consequent development of hyperinsulinemia/hypoglycemia, and the cells must withstand immune rejection. Although it has been reported that ES and iPS cells can be differentiated into cells that produce insulin, these cells have a low content of insulin and a high rate of apoptosis and generally lack the capacity to normalize blood glucose in diabetic animals. Thus, ES and iPS cells have not been useful for the large-scale production of differentiated islet cells. During embryogenesis, the pancreas, liver, and gastrointestinal tract are all derived from the anterior endoderm, and transdifferentiation of the pancreas to liver and vice versa has been observed in a number of pathologic conditions. There is also substantial evidence that multipotential stem cells reside within gastric glands and intestinal crypts. These observations suggest that hepatic, pancreatic and/or gastrointestinal precursor cells may be reasonable candidates for cell-based therapy for diabetes, although it is unclear whether insulin-producing cells derived from pancreatic stem cells or liver progenitors can be expanded in vitro to clinically useful numbers. Bone marrow stem cells and neural stem cells both reportedly have the capacity to generate insulin-producing cells, but there is no convincing evidence that either cell type will be clinically useful. ++ Nervous System ++ Substantial progress has been made in developing methodologies for generating neural cells from different stem cell populations. Human ES or iPS cells can be induced to generate cells with the properties of neural stem cells, and these cells in turn give rise to neurons, oligodendroglia, and astrocytes. Reasonably large numbers of these cells can be transplanted into the rodent brain with formation of appropriate cell types and no tumor formation. Multipotent stem cells present in the adult brain also can be easily amplified in number and used to generate all the major neural cell types, but the invasive procedures that would be necessary to obtain autologous cells are a major limitation. Fetal neural stem cells derived from miscarriages or abortions are an alternative but may raise ethical concerns. Nevertheless, a clinical trial of fetal neural stem cells in Batten's disease is in progress. Transdifferentiation of bone marrow and adipose stem cells into neural stem cells, and vice versa, has been reported by numerous investigators, and clinical trials of such cells have begun for a number of neurologic disorders. Clinical trials of a conditionally immortalized human cell line and of human umbilical cord blood cells in stroke are planned. Some evidence suggests that epidermal stem cells also have the potential for neural regeneration. Neurologic disorders that have been targeted for stem cell therapies include spinal cord injury, amyotrophic lateral sclerosis (ALS), stroke, traumatic brain injury, Batten's disease, and Parkinson's disease. In Parkinson's disease the major motor features of the disorder result from the loss of a single cell population—dopaminergic neurons within the substantia nigra—suggesting that cell replacement should be relatively straightforward. However, two clinical trials of fetal nigral transplantation failed to meet their primary endpoint and were complicated by the development of dyskinesia. Transplantation of stem cell–derived dopamine-producing cells offers a number of potential advantages over the fetal transplants, including the ability of stem cells to migrate and disperse within tissue, the potential for engineering regulatable release of dopamine, and the ability to engineer cells to produce factors that will enhance cell survival. Nevertheless, the experience with fetal transplants points out the difficulties that may be encountered. ++ At least some of the neurologic dysfunction after spinal cord injury reflects demyelination, and both ES cells and marrow-derived stem cells are able to facilitate remyelination after experimental spinal cord injury. Clinical trials of marrow-derived stem cells in this disorder have commenced in a number of countries, and this may be the first disease targeted for the clinical use of ES cells. Marrow-derived stem cells also are being used in the treatment of stroke, traumatic brain injury, and ALS, in which possible benefits are more likely to be due to indirect trophic effects or remyelination than to neuron replacement. At present no population of transplanted stem cells has been shown to have the capacity to generate neurons that extend axons over long distances to form synaptic connections (as would be necessary for replacement of upper motor neurons in ALS, stroke, or other disorders). ++ Liver ++ Liver transplantation is currently the only successful treatment for end-stage liver diseases, but the shortage of liver grafts is a serious problem. Clinical trials of hepatocyte transplantation demonstrate that it potentially can substitute for organ transplantation, but this approach is limited by the paucity of available cells. Potential sources of stem cells for regenerative strategies include endogenous liver stem cells (such as oval cells), ES cells, bone marrow cells, and umbilical cord blood cells. Although a series of studies in humans as well as animals suggested that transplanted bone marrow stem cells can generate hepatocytes, fusion of the transplanted cells with endogenous liver cells, giving the erroneous appearance of new hepatocytes, appears to be the underlying event in most circumstances. The available evidence suggests that transplanted hematopoietic cells can generate hepatocyte-like cells in the liver only at a very low frequency. ES cells can be differentiated into hepatocytes and transplanted in animal models of liver failure without the formation of teratomas. ++ Other Organ Systems and the Future ++ The use of stem cells in regenerative strategies has been studied for many other organ systems and cell types, including skin, eye, cartilage, bone, kidney, lung, endometrium, vascular endothelium, smooth muscle, and striated muscle, among others. In fact, the potential for stem cell regeneration of damaged organs and tissues is virtually limitless. However, there are numerous obstacles to be overcome before stem cell therapies can become a widespread clinical reality. Only hematopoietic stem cells have been adequately characterized by surface markers so that they can be unambiguously identified, a prerequisite for reliable clinical applications. The pathways for differentiating stem cells into specific cellular phenotypes are largely unknown, and there is little ability at present to control the migration of transplanted cells or predict the response of the cells to the environment of diseased organs. Some strategies may employ the coadministration of scaffolding, artificial extracellular matrix, and/or growth factors to orchestrate differentiation of stem cells and their organization into appropriate constituents of the organ. There is currently no way to image stem cells in vivo after transplantation into humans, and it will be necessary to develop techniques to accomplish this. Fortunately, stem cells can be engineered before transplantation to contain a contrast agent that may make this feasible. The potential for tumor formation and the problems associated with immune rejection are impediments, and it will also be necessary to develop techniques for ensuring vascularization of regenerated tissues. There already are many strategies for cell replacement, including vasoactive endothelial growth factor (VEGF) coadministration to foster vascularization of the transplant. Some strategies also include genetically engineering stem cells to have an inducible suicide gene so that the cells can be easily eradicated in the event of tumor formation or another complication. The potential for stem cell therapies to revolutionize medical care is extraordinary, and disorders such as myocardial infarction, diabetes, and Parkinson's disease, among many others, will become potentially curable. However, such stem cell–based therapies are still at a very early stage of development, and perfection of techniques for clinical transplantation of predictable, well-characterized cells is going to be a difficult and lengthy undertaking. ++ Ethical Issues ++ Stem cell therapies raise ethical and socially contentious issues that must be addressed in parallel with the scientific and medical opportunities. This society has great diversity with respect to religious beliefs, concepts of individual rights, tolerance for uncertainty and risk, and boundaries for how scientific interventions should be used to alter the outcome of disease. In the United States, the federal government has authorized research using existing human ES cell lines but still restricts the use of federal funds for developing new human ES cell lines. Ongoing studies of existing lines have indicated that they develop abnormalities with time in culture and that they may be contaminated with mouse proteins. These findings point out the need to develop new human ES cell lines. The development of iPS cell technology may lessen the need for deriving new ES cell lines, but it is still not clear whether the differences in gene expression by ES and iPS cells are important for potential clinical use. ++ In considering ethical issues associated with the use of stem cells, it is helpful to draw from experience with other scientific advances, such as organ transplantation, recombinant DNA technology, implantation of mechanical devices, neuroscience and cognitive research, in vitro fertilization, and prenatal genetic testing. These and other precedents have pointed to the importance of understanding and testing fundamental biology in the laboratory setting and in animal models before applying new techniques in carefully controlled clinical trials. When these trials occur, they must include full informed consent and provide for careful oversight by external review groups. ++ Ultimately, there will be medical interventions that are scientifically feasible but ethically or socially unacceptable to some members of a society. Stem cell research raises fundamentally difficult questions about the definition of human life, and it has raised deep fears about the ability to balance issues of justice and safety with the needs of critically ill patients. Health care providers and experts with backgrounds in ethics, law, and sociology, must help guard against the premature or inappropriate application of stem cell therapies and the inappropriate use of vulnerable population groups. However, these therapies offer important new strategies for the treatment of otherwise irreversible disorders. An open dialogue among the scientific community, physicians, patients and their advocates, lawmakers, and the lay population is critically important to raise and address important ethical issues and balance the benefits and risks associated with stem cell transfer. + Further Readings Print Section ++Higgs DR: A new dawn for stem-cell therapy. N Engl J Med 358:964, 2008 [PubMed: 18305272] ++Kiskinis E, Eggan K: Progress toward the clinical application of patient-specific pluripotent stem cells. J Clin Invest 120:51, 2010 [PubMed: 20051636] ++Park IH et al: Disease-specific induced pluripotent stem cells. Cell 134:877, 2008 [PubMed: 18691744] ++Parmacek MS, Epstein JA: Cardiomyocyte renewal. N Engl J Med 361:86, 2009 [PubMed: 19571289] ++Riazi AM et al: Stem cell sources for regenerative medicine. Methods Mol Biol 482:55, 2009 [PubMed: 19089350]


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Denim toiletry bags / pencil cases FREE TUTORIAL with pictures - Ompeluohje…
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I immediately fell in love with this hotel room. It was black and white interior and was completely up to date and modern. I actually wanted to stay in that king size comfy bed and relax for a few hours. Perfect break from the go-go-go...More
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Biological Activity
Basic fibroblast growth factor (bFGF) mimetic. Mimics the neuroprotective effects of bFGF; prevents glutamate-induced neuronal death. Increases levels of CALB1 gene expression in cerebrocortical neurons. Triggers phosphorylation of FGFR, ERK1 and ERK2.
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References are publications that support the products' biological activity.
Murayama et al (2013) SUN11602, a novel aniline compound, mimics the neuroprotective mechanisms of basic fibroblast growth factor. ACS Chem.Neurosci. 4 266 PMID: 23421678
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Keywords: SUN11602 basic fibroblast growth factor bFGF calcium binding protein calbindin-D28k Calb FGFR receptor ERK1 ERK2 FGFR
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Literature in this Area
Stem Cells Scientific Review
Written by Kirsty E. Clarke, Victoria B. Christie, Andy Whiting and Stefan A. Przyborski, this review provides an overview of the use of small molecules in the control of stem cell growth and differentiation. Key signaling pathways are highlighted, and the regulation of ES cell self-renewal and somatic cell reprogramming is discussed. Compounds available from Tocris are listed.
Depression Poster
Major depressive disorder is characterized by depressed mood and a loss of interest and/or pleasure. Updated in 2015 this poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder, as well as outlining the pharmacology of currently approved antidepressant drugs.


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There are two unfortunate and inevitable facts of life. The first is that everyone will eventually die. As you start to age, Father Time will make it apparently clear. Read these tips so you know how to deal with the various aspects of growing older.
Control your frowning to prevent wrinkles. As crazy as it make sound it's really true. You can pinch yourself to make sure you stop. When you are aware of your frowning habit you will be able to break it.
One great way to keep from worrying about aging is to let go of the obsession with numbers. You can drive yourself crazy worrying about your weight and age. Do things that are fun and let your doctor deal with your numbers.
You should not concentrate on the numbers of your life. Doctors are paid good money to bother about numbers such as age, weight, and height. If you worry about things like age, weight and your ever decreasing height as you age, you'll drive yourself crazy. Stop and smell the roses, and you will stay mentally young throughout your life.
A balanced diet, while important at any age, is especially important as you age. Your diet should contain low amounts of saturated fat, and lots of fresh fruits and veggies, whole grains and other sources of natural fiber. By doing this, you will have all the nutrients you need.
You need to sleep the proper amount of time based on your age. In order to stay healthy you should strive to sleep at least seven hours every night. Failing to get sufficient sleep is likely to result in grouchiness and lack of fulfillment in ordinarily satisfying activities.
Turn your house into a home by personalizing it. As you age, you may find that you cannot stay in the place you thought you would be forever. If you find yourself in a new living arrangement, look for ways to surround yourself with the things that you love most.
Friendships will energize you and fill your emotions with love and happiness. You will never be too old to find new friends. Meet new people by strike up conversations with strangers in the grocery line, on the bus or at an event. It will improve your life.
Through the course of your life, your house begins to feel like a safe place. Take the time to turn your home into a comfortable refuge, so that you know you have a place of rest if the rigors of the outside world have been too much for you. Your home will always be waiting for you; ready to provide comfort.
Life is a journey that should be explored and enjoyed. If you set goals for yourself, you will feel like you have risen.
Remain friends only with people who are positive and uplifting. There have been studies conducted that have found if you laugh a lot and spend much of your time smiling, you will have less wrinkles, and you will look younger. Choose to spend time with people who make you happy, smile and laugh, and not those who are so negative.
Make sure you avoid extreme environmental conditions. When you're out in the sun or in a really cold environment for a long time, you could potentially damage your skin. This not only makes your skin all wrinkly and scaly, but it also raises your risk for diseases, including skin cancer.
You should have a healthy diet. Make sure you are taking in a balanced diet with plenty of fruits and veggies. Eating right will aid mental and physical health, in addition to properly charging up your body to get you through your day.
Do not fall. The statistics show that falling is the cause of the most serious injuries in senior citizens. Walking is a low impact exercise that can really make a difference in your health. To lower your risk of fractures, you need to increase bone density by not only doing weight training, but also getting enough vitamin D and calcium.
Talk with your doctor about taking anti-growing older supplements, he can let you know which ones are best for you. You should have a balanced intake of antioxidants, multivitamins and possibly anti-inflammatory medication. Consuming these will help your body feel and perform as though it were younger. Include these in any daily plan you build.
To contest aging, you need to develop a better diet quality. Your body needs even more nutrients as you age, so be sure to pursue a diet full of healthy fruits and vegetables, lean meats and whole grains. Have three moderately sized meals, and don't eat many snacks.
We all get a little bit older every day and there isn't a single thing you can do to stop it. So make sure that you're also getting wiser as you get older. Be sure that you're using the tips provided to you in the article above to do the little things to ensure that you age well and avoid complications.


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Kirmac Collision Center - Auburn
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Category: Collision
Service Date: 10/28/2011
Review Created: 11/11/2011
This review was collected via phone interview by Customer Research Inc.


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Semana de Campo Santa Margarida 2016
Semana de Campo Santa Margarida 2016
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forum lottery from DanielaMaciel
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Boeing 767-300 de TAM con colores de Disney. Aeropuerto Internacional Ministro Pistarini (SAEZ/EZE), Ezeiza, Julio 2017.
TAM Boeing 767-300 with Disney livery. Ministro Pistarini International Airport (SAEZ/EZE), Ezeiza, July 2017.
This image was taken @ Pt. Lobos State Reserve overlooking a Cypress Grove. The Reserve is located in Northern California.
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Jul 13, 2017 - Josh (left) with his partially built 'sailing canoe' at Browns Pt
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Canon XTi (400D)
Tamron 17-50mm @30mm
1/60 sec. @ f/5.6 (trying to catch a wave!)
Explored...thank you much! (The first photo to make Explore on the new account)
Local: Aeroporto de Guaxupé MG
Modelo: 172M
Matrícula: PT-KHP
Data da Foto : 07/09/2013
Local: Aeroporto de Guaxupé MG
Modelo: V35B
Matrícula: PT-DNJ
Data da Foto : 25/01/2014
sent on 23 Feb, 2017
travel time 168 days


text:
boring words
HOW TO SPELL PLURAL NOUNS - TeachersPayTeachers.com
Get these 8 grammar mini anchor charts to glue in your students interactive writing journals. They are a great resource to help your students remember some important grammar rules. Topics included: Punctuation Rules, Capitalization Rules, Comma Rules, Quotation Marks, Subject and Verb Agreement, Subject and Predicate, and Compound and Complex Sentences!
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Manish Malhotra bridal collection. Bridelan- Personal shopper & style consultants for Indian/NRI weddings, website www.bridelan.com #ManishMalhotra #weddinglehenga #Bridelan #BridelanIndia.
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AALIA BHATT Looking Soo Simply Stunning In A Figure Hugging Designer Ethnicwear That Accentuates Her Figure Sooo Prominently Without Revealing Any Flesh...Isn't That What Being Classy Is All About?!!


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Adele does charity work on music breakSinger Adele has been focusing on her charity work during her music break. She visited an education centre in west London to meet disadvantaged youngsters. Business Standard, 3 weeks ago
507 images for Adele
Adele shares a cuppa with London fire brigade heroes
London Fire Brigade @LondonFire tweets: Adele enjoyed a cup of tea with Chelsea firefighters yesterday and thanked them for their work. We are so humbled by everyone's support.Rediff.com, 2 months ago Adele visits London firefighters after tower block blaze DNA, 2 months ago Adele thanks Chelsea firefighters with a 'tea and a cuddle' after Grenfell Tower heroics The Telegraph UK, 2 months ago
Daniel Craig in talks to return as James Bond, Adele too may join the team
Producer Barbara Broccoli is reportedly trying to bring back the 'Skyfall' team.DNA, 1 month ago
Adele visits London's Grenfell Tower after massive fire
Singer Adele made an emotional visit to London's Grenfell Tower to offer support to those affected by the deadly fire that killed at least 12 people and injured 74 others.DNA, 2 months ago Adele makes emotional appearance at Grenfell Tower after fire Rediff.com, 2 months ago Adele 'comforts' people affected by Grenfell Tower fire during emotional visit The Telegraph UK, 2 months ago
Remember those Irish lads that sang with Adele? They've got exciting news
We're very excited for this.Breaking News, 3 weeks ago
DJ Khaled wants to collaborate with Adele
DJ Khaled has expressed his desire to collaborate with Grammy-winning singer Adele, among other artistes.DNA, 2 days ago
Harry Styles set for his own BBC special
Singer Harry Styles will have his own hour-long special at BBC after Michael Buble and Adele.DNA, 3 days ago
Adele's special gesture for Grenfell Tower survivors
Singer Adele hosted a special "Despicable Me 3" private screening for Grenfell Tower survivors. The Grammy-winning singer held the screening for some of the tragedy's younger survivors and their families just before the weekend, reported Variety. According to ...Business Standard, 2 weeks ago Adele takes Grenfell Tower survivors to private 'Despicable Me 3' screening Business Standard, 2 weeks ago Adele takes young Grenfell survivors to a film screening The Telegraph UK, 2 weeks ago Adele hosts private film screening for Grenfell Tower victims Business Standard, 2 weeks ago
Adele's fans unite to support singer after she cancels gigs
Adele's fans have come out in a huge numbers to support the singer after she cancelled the two final shows of her tour due to health issues. The 29-year-old singer decided not to go through with the final two dates of her tour after she was diagnosed with ...Business Standard, 1 month ago Adele's fans sing for her, after she cancels gigs DNA, 1 month ago 'Devastated' Adele cancels last two Wembley appearances The Telegraph UK, 1 month ago
Adele says she may never go on tour again
Singer Adele, whose "Hello" tour is coming to an end this weekend, hinted that she might never go on tour again. The "Rolling in the Deep" hitmaker penned a heartfelt letter, which was displayed during her concert at Wembley Stadium in London on Wednesday, ...Business Standard, 1 month ago Adele shares why she may never tour again Business Standard, 1 month ago
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P.O. Box 880
Deridder, Louisiana 70634
United States
|Areas of Practice
|1) Insurance Defense, 2) Probate, 3) Insurance, 4) Oil and Gas, 5) Real Estate, 6) Corporate Law, 7) Family Law and 8) General Civil Trial Practice
|Admitted Year
|Louisiana State University (LL.B., 1959)
|Most recent firm
|Hall, Lestage & Landreneau
|Relevant Jobs
Legal Assistant-Personal Injury
Legal assistant to manage personal injury files. Must have previous experience. Organized, energetic, and have the ability to communicate with clients on a daily basis. Attention to detail, and ...
Apply now
Litigation Associate
A well-established AV rated defense firm seeking an experienced associate with 1-5 yrs experience preferred for an active federal and state litigation and business defense practice. The ideal cand...
Apply now
Litigation Paralegal & Legal Secretary
USA-LA-New Orleans
Litigation Paralegal The candidate should have 2+ years experience in a business litigation support setting, a strong work ethic, keen attention to detail, and excellent organizational skills. Must be...
Apply now
|+ View more jobs
A. Harrison Barnes is a well-known attorney throughout the United States. As a member of the Malibu community, Harrison is committed to serving the needs of Malibu residents and businesses in legal matters.
Alan Singer is a partner in Morgan Lewis's Securities Practice. Mr. Singer advises companies with regard to a diverse range of corporate and securities matters.


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Wessex Health Network
17 Stour Road
07886 800348
Wessex Health Network
17 Stour Road
07886 800348
Who is counselling for?
People often think that counselling is just for people who have had a 'bad childhood' or have been abused; However the reality is counselling is for everyone and anyone who wants to reflect on where they are in life and make some changes.
Over our lifetime we are exposed to many adverse experiences, most of which we take in our stride, however cumulatively it all adds up and can start to impinge on our enjoyment of life and our ability to deal with the stress and strain of life.
This is sometimes highlighted in the moments of life where we are most vulnerable, things bubble up like a volcano and suddenly erupt!
How can counselling help?
Counselling is a talking therapy which allows you to explore your thoughts and feelings in a safe space without Judgement. The core conditions of a person centred counsellor are to offer positive regard, to be non-judgemental, to be genuine, honest and empathic (to see things from your point of view). When a person experiences the core conditions, over time, they are able to work through their own thoughts and feelings and make long lasting changes.
As a professional BACP counsellor I believe most individuals have the internal resources needed for growth and change.
Where do you go to access help?
Support from the NHS is improving and that is great news, however most counselling on the NHS is time limited and waiting lists are often several months.
If you:
Enquire today to find out how I can help.
BACP Acreddited Level Five Diploma
in Person Person Centred Therapy.
Awarded 2013.
Diploma in Child Psychology.
Awarded 2015.
Mind (Mental health charity.)
Counselling, Advocacy and Parenting Support.
Private Practice
To ensure best practice, as with all qualified and registered BACP counsellors, I attend regular supervision. Supervision is a place for counsellors to work with a qualified supervisor to explore what has come up for them whilst working with a client, there is minimal disclosure about the client and the objective is to ensure the counsellor is working within the BACP ethical framework.
Whilst I am qualified and experienced in a wide range of issues that come up in life, over the years I have developed a particular interest in supporting women through the transition into motherhood and all the challenges that come with that change.
I also have great interest in supporting parents of children who display challenging behaviour and sensory issues.
Now I'm going to be honest with you here, counselling is a process, changes are unlikely to occur overnight and you may feel worse before you feel better so for that reason and to offer you the best chance of receiving benefit from counselling I offer six session courses with the option to add further sessions if you wish to continue.
I offer an initial meeting (45 minutes) to allow you to assess if counselling is right for you and to see if you have the desire to work through and make some changes in your life, this session is just £29.
When you are ready to commit a six session course is £299.
Most clients start to experience change within 6-10 sessions, however, everyone is different and results are not guaranteed.
25 % Concession available for low income families (Household income under £20k)
Payment plans available, sessions are subject to a 24-hour cancellation policy.
Payments can be made via Paypal, Cheque or BACS
Professional counselling can be arranged at several local venues; home visits are available providing that it is possible to maintain confidentiality and there are no interruptions or distractions, each case will be assessed individually and balanced with the client's needs.
|Online counselling:
|Telephone counselling:
|Face to face counselling:
|Sign language:
|Other languages:
Weekdays and Evenings.
|Older adults
|Employee Assistance Programme


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Windsor Martinique Hotel, Rio de Janeiro
- Free buffet breakfast and free WiFi
Main amenities
- 116 guestrooms
- Near the beach
- Restaurant and bar/lounge
- Outdoor pool
- Fitness center
- 24-hour front desk
- Coffee/tea in a common area
- Air conditioning
- Daily housekeeping
- Self-serve laundry
- Multilingual staff
- Free newspapers in the lobby
- Free buffet breakfast and free WiFi
For families
- Private bathroom
- Free toiletries
- Daily housekeeping
- Laundry facilities
- Hair dryer
- Blackout drapes/curtains
What's around
- In Copacabana
- Leblon Beach (2.4 mi / 3.8 km)
- Carlos Drummond de Andrade Statue (0.3 mi / 0.5 km)
- Dorival Caymmi Statue (0.4 mi / 0.7 km)
- Copacabana Fort (0.5 mi / 0.8 km)
- Praca General Osorio (0.7 mi / 1.2 km)
Windsor Martinique Hotel, Rio de Janeiro
Hotel Info: 866-539-8117from $81
- Standard Double Room, 1 Double Bed
- Superior Double Room, 1 Double Bed
- Standard Twin Room, 2 Twin Beds
- Superior Twin Room, 2 Twin Beds
More great choices
At a glance
Key facts
Hotel size
- This hotel has 116 rooms
- This hotel is arranged over 7 floors
- Check-in time starts at 2 PM
- Check-out time is noon
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
- Minimum check-in age is 18
Travelling with others
- One child (10 years old and younger) stays free when occupying the parent or guardian's room, using existing bedding
- Parents must have child's birth certificate and photo ID *
- No cribs (infant beds)
- Pets not allowed
- Free WiFi in public areas
- Free WiFi in rooms
Nearby Three Star Rio de Janeiro hotels
In the hotel
- Free buffet breakfast
- Restaurant
- Bar/lounge
- Coffee shop/café
- 24-hour room service
- Coffee/tea in a common area
- Outdoor pool
- Pool umbrellas
- Fitness facilities
- Bicycle rentals nearby
- Golfing nearby
- Hiking/biking trails nearby
- Surfing/boogie boarding nearby
- 24-hour front desk
- Tours/ticket assistance
- Laundry facilities
- Free newspapers in lobby
- Luggage storage
- Multilingual staff
In the room
- In-room climate control (air conditioning)
- Air conditioning
- Minibar
- Blackout drapes/curtains
- Soundproofed rooms
- Private bathroom
- Shower only
- Bidet
- Free toiletries
- Hair dryer
- 26-inch LCD TV
- Cable TV channels
- Desk
- Free WiFi
- Phone
- Daily housekeeping
- In-room safe
Top Rio de Janeiro hotels
Recently reviewed hotels in Rio de Janeiro
- Arena Leme Hotel
"Nice hotel. Great location. Friendly staff. Needed late check out. Was arranged immediately. We're helpful with recommendations for taxis, tours and food. "Aug 13, 2017
- PortoBay Rio InternacionalFrom
"Good service and value"Aug 13, 2017
- Hilton Rio de Janeiro CopacabanaFrom
"I paid in advance for breakfast. One day I asked if I could have the breakfast in the room and they brought it. The bill included a full charge for this room service. I told them…"Aug 11, 2017
- Grand Hyatt Rio De JaneiroFrom
"Perhaps the best hotel and facilities in Rio. The only downside is that is far from everything else but the area and quality of the hotel more than make it worth having long…"Aug 11, 2017
Also popular with travelers from the USA
Special features
DiningRestaurante Martinique - This brasserie serves breakfast, lunch, and dinner.
Windsor Martinique Hotel, Rio de Janeiro's small print
Also known as
- Hotel Windsor Martinique
- Windsor Martinique
- Windsor Martinique Hotel
- Windsor Martinique Hotel Rio de Janeiro
- Windsor Martinique Rio de Janeiro
- Hotel Martinique Copa
- Martinique Copa Hotel
- Martinique Copa Rio De Janeiro
- Windsor Martinique Hotel Rio De Janeiro, Brazil
Parents or a legal guardian traveling with children under 18 years must present the child's birth certificate and an identity card with photo (passport, for example) at the check-in. For international travels from Brazil, if just one of the parents is traveling with the child, she/he must present – in addition to the child's certificate of birth and identity card with photo – a letter authorizing the trip signed by the other parent with a notarial certification of signature. In case the parents or the legal guardian, as applicable, cannot or are unwilling to give this authorization, a judicial authorization is required. People who intend to travel to Brazil with children must consult with the Brazilian consulate before traveling for more information.
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.
Is the description of this hotel not correct? Tell us


text:
Silverado Naperville
Talk to a Family Advisor:
COSTSContact for Details
AVAILABILITYSchedule a Tour
PAYMENT OPTIONSContact for Details
Reviews of Silverado Naperville
Waitingforanswers August 30, 2016
I am a friend or relative of resident
Thank you for taking the time to review our community. Creating a safe, lively environment where residents can thrive is Silverado's top priority, and we welcome feedback so that we can continue to improve upon the world-class environment for which we are known. We offer a continuum of care for all stages of memory loss and offer specialized programs dedicated to the different needs of our residents. We regret that your experience did not match up to the standards we consistently provide to our residents and their families. We take all comments very seriously and would love to have an opportunity to address your concerns directly. Please reach out to our Naperville Administrator Linda Wylder at (630)-778-9221
Barbara501162 July 11, 2016
I visited this facility
Barbara, we are happy to hear that you had a positive experience. Silverado is a socially vibrant community filled with visitors and pets, and often times children as well. As you noted, our vibrant and family-like environment makes Silverado feel like a home. Thanks for your feedback!
Pam630172 July 01, 2016
I visited this facility
Marquerite January 31, 2015
I am a friend or relative of resident
Marquerite, thank you for sharing your Silverado story. We are glad that you had a positive experience and enjoy our home-like environment. At Silverado, we are one big family and treat our residents with love, dignity and respect. Pet therapy is a cornerstone to our unique philosophy of care and our community pets bring smiles to our residents' faces every day. Thank you again for your comments!
Pat48 January 31, 2014
I am a friend or relative of a resident
Pat, thanks for taking the time to review our community. We are glad that you had a positive experience. As you noted Silverado, we offer a social and engaging environment and plan daily resident activities. We are happy to hear that your father is thriving at our Naperville community!
Write a Review
From Silverado Naperville
Features of Silverado Naperville
- Minimum Rate: $5700/month
Dining options
- Dining Room Shared Meals
- Room Service For Meals
- Beauty Barber Shop
- Resident Transportation
- Tv Room
- Garden And Patio
Cleaning services
- Laundry For Linens
- Housekeeping
- Laundry For Clothing
Health services
- Hospice Care
- Medication Management
- Nurse On Staff: Yes
- Music
- Games
- Stories
- Gardening
- Arts And Crafts
Guest services
- Guest Parking
- Guests At Mealtime
- Respite Care
Location of Silverado Naperville
Senior Living Nearby
Helpful Articles
- 8 Things to Do When You First Learn Your Loved One Has Alzheimer's
- 10 Signs It Might Be Time for Memory Care
- 8 Red Flags That an Alzheimer's Caregiver Needs a Break
- How to Tell if Someone With Alzheimer's Needs Assisted Living
- Q&A: Is a Memory Care Unit or Nursing Home Better?
- Memory Care vs. Assisted Living
- Memory Care Checklist: What to Look for, What to Ask
- How to Find the Alzheimer's Care Facility That is Right for You
- Paying for Memory Care: 7 Things to Know
- Q&A: How Can I Ease the Transition into an Alzheimer's Unit?
Top Cities for Assisted Living
Get Cost Information
Get full access to reviews, cost information, and amenities


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This week, CRF Global Youth Ambassador Brighton Kaoma met with President Barack Obama at the Obama Foundation to discuss the role of young African leaders in bringing about sustainable solutions to the challenges their communities face.
Being the only young African to meet President Obama from a pool of 1,000 Mandela Washington Fellows of 2017 was a life changing experience for Brighton. He says, "During my half an hour meeting with President Barack Obama, we discussed issues around the global threat of climate change and why it's relevant for each and everyone to rise to the occasion and act to mitigate and adapt to this challenge of our generation."
We congratulate you Brighton, and are so proud of all that you have been doing and stand for!
Our Cape Town based staff and South African regional trainers recently participated in a two-day training with Gun Free South Africa, ahead of our European union funded community safety project.
Adele Kirsten, the director of Gun Free South Africa facilitated the interactive training along with her colleague Nurahn Ryklief, Communications and Community Development Officer. Here, the team are doing a community mapping exercise, reflecting on personal gun violence experiences.Read More
New issue-based training kicked off in Lusaka, Zambia this past week. Young reporters learnt new ideas on the topic of water, droughts and floods to implement new radio shows at their community radio stations.
In the last 30 years, the temperature has been increasing at 0.6 degrees per decade in Zambia and all areas in the country have been experiencing climatic changes, which have contributed to floods and droughts. The training for our young reporters focuses on these issues, giving capacity to the youth reporters so that they can produce more shows on floods and droughts and help find solutions. Our regional manager, Leader Kanyiki (in the red shirt) is traveling to all the young reporter sites to support them with the training.
On Universal Children's Day, November 20th, our street youth reporters in Kinshasa advocate for their rights. They observed this day together with church members and pastors from the 'Assemblies of God' Church, in the municipality of Kisensu in the DRC. This day observed by the United Nations, is celebrated each year to advocate, promote and celebrate children's rights, translating into dialogues and actions that will build a better world for children.
After the main church sermon, our partner from REEJER, Denis Mabwa introduced the issue of child witchcraft, and three testimonial stories were shared by the youth reporters. Our partners were given a space to talk about how the Church can play a negative role in not only the rejection and abandonment of children accused of witchcraft but also to entrench this belief of child witches in the community. It was pointed out that some point in Kinshasa, out of 100% of so-called street...Read More
Our Ubuntu Lab conference, held alongside the Youth Radio Awards in September, provided the space for young people to deepen their understanding of Ubuntu, and share ideas on how they can bring the practice of humanity to our struggles in South Africa.
In addition to panel discussions on Ubuntu, listening to artists and poets, hot debates, and creating their own skits and performances, the group of approximately 40 youth had the opportunity to have face to face discussions with some inspiring individuals in the 'Talking Heads' session. In this session, the youth gathered in rotating small groups to have discussions with a writer, poet, astronomer, freestyle footballer, social justice activist, TV presenter, entrepreneur, LGBTI activist and more.
See more photos from the Ubuntu Lab held at the Castle of Good Hope in Cape Town.Read More


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Barron's Chemistry- The Physical Setting - Comprehensive chemistry test practice
Barron's Chemistry- The Physical Setting serves as ideal preparation for chemistry tests. With practice questions and answer, assess your performance according to standard set by the state.
Author NameAlbert S. Tarendash M.S.
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text: I want a mil-dot or ballistic plex, an AO to focus down to at least 25 yards, 10 to 16 top power, target turrets would be nice but not a must, a scope that could handle a centerfire in the future, matte finish, preferably in a less than 50MM objective all in the low $300 or less range. Any thoughts? It is going on a custom 10/22 for now and I cannot decide if I should go cheap or spend more money and get a mid range cost multipurpose scope. I was kind of thinking Bushnell 3200 5-15 tactical with mil-dot and target knobs, burris fullfield II 4.5 X 14 with ballestic plex, buckmaster 4.5 -14 or 6-18 with mil-dot, clearidge XP 4.5-14, Muller or Millet. Then there are the cheap scopes Tasco, centerpoint, the fake Leupolds, Hawke (they have cheaper models don't know their quality), simmoms, others.


text:
Cowboys Host First Training Camp At Ford Center Thunder Tix Not Seeing Boost From George West Discusses Leaving Warriors For Clippers Marlins Sale Could Mean $65M Payout For Public NBA Investigating Pacers' Claim Of Lakers Tampering Raiders Popular In L.A. Despite Chargers Presence Loria Has No Reservations About Selling Marlins Franchise Notes Prospective Marlins Owners To Get Rid Of Samson Sox Owner Wants To Rename Yawkey Way
Upcoming Conferences and Events
SBD/January 24, 2014/Franchises
Capitals Look To Enhance Fan Experience With Technology Such As Google Glass, Skybox
Published January 24, 2014
SEEING IS BELIEVING: In Sacramento, Matt Kawahara notes the NBA Kings will "outfit a handful of team personnel with Google Glass and broadcast live video taken with the futuristic glasses to fans in a variety of ways -- on the video board inside Sleep Train Arena," over Friday's local TV broadcast and "across social media." A team spokesperson said that among those wearing Google Glass will be "members of the Kings' dance team, an announcer and mascot Slamson." All told, "about a dozen of the glasses will be deployed." Kings President Chris Granger said, "It's about giving fans a unique perspective. We'd like our fans to be able to experience what it's like to run through the tunnel like a player, what it's like to be near the player huddle like a sideline reporter is, what it's like to be a Kings dancer on the court." Kawahara notes CrowdOptic "employed the same technology the Kings will use" on Friday night at several Stanford Univ. athletic events in recent months. Stanford Senior Assistant AD/Communications Kurt Svoboda said that those included "a basketball game and a football game at which non-athletes wore the glasses on the field, in the press box and in postgame interview sessions, with the video then shown in-venue" (SACRAMENTO BEE, 1/24).


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The man coaching the Portland Trail Blazers on Monday spent some time talking about being "in the moment," a philosophy that is two parts Zen, one part coach-speak and one part sheer psychological necessity.
The moment? For the sake of their sanity, the Blazers can focus only on the present, because spending even two seconds on the past is wholly depressing.
On Saturday night, the Blazers watched Greg Oden, their burly, bright young center, crumble to the court with a gruesome knee injury. He is lost for the season — for the second time in his three-year career.
Portland was already without two key forwards, Travis Outlaw and Nicolas Batum, each of whom had surgery that will require months of rehabilitation. Rudy Fernandez, the team's electrifying swingman, is battling a nerve problem in his back.
The Blazers began a four-game trip Monday in New York with just nine healthy players — including 36-year-old Juwan Howard and Dante Cunningham, a second-round draft pick in June.Continue reading the main story
They also arrived without their coach, Nate McMillan, who had surgery for a ruptured Achilles' tendon Monday. McMillan, a former N.B.A. guard, was injured last Friday, when he joined the team for practice because the team did not have enough bodies to play five on five.
The attrition began over the summer, when two rookies required surgery. But the team's maladies go way beyond the court.
In November, the owner Paul Allen was found to have non-Hodgkin's lymphoma. He is undergoing chemotherapy. Maurice Lucas, an assistant coach, has been hospitalized with a recurrence of bladder cancer.
Now Oden, a defensive force and one of the most promising young centers in the N.B.A., is facing a long rehabilitation after fracturing his left patella.
"Sometimes," the star forward LaMarcus Aldridge said, "you really don't believe it. You're just like, what's next?"
They have been asking that question in Portland for months.
The Blazers have assembled an enviably deep and talented young roster, a team expected to be a playoff force immediately and a Western Conference power for years to come.
At the core is Oden, the No. 1 pick in the 2007 draft, along with Aldridge and the All-Star guard Brandon Roy. Moment by moment, their promising season seems to be unraveling.
"We run the gamut of emotions," said the assistant Dean Demopoulos, who is standing in for McMillan this week and trying to keep his team fixed on the present. "You go up and down some, but the underlying emotion is determination."
Portland has a sturdy 13-9 record playing in the tough Western Conference. But the Blazers have lost four of their last five games after a 93-84 loss to the Knicks in the opening game of this trip through the East, which includes stops in Indiana, Cleveland and Milwaukee.
They will be ever more reliant on Roy and Aldridge, who two years ago carried the Blazers to a 41-41 record after Oden's rookie season was wiped out by knee surgery.
Roy, one of the top guards in the league, was averaging 20.4 points and 5 assists. Aldridge, who was averaging 14.8 points and 7.7 rebounds, will feel Oden's absence the most and will surely spend more time at center.
Joel Przybilla, a solid rebounder and shot blocker, is starting for Oden, but with little support behind him.
"We feel like the guys that are stepping in can handle some of the load," General Manager Kevin Pritchard said. "They can't replace it, but they can handle some of it."
Psychologically, perhaps nothing was tougher than seeing Oden collapse Saturday night at the Rose Garden. A celebrated draft pick in 2007, Oden has already had to battle ill perceptions and old ghosts. He has been compared, all too often, to Sam Bowie, the promising center who was drafted by the Blazers in 1984 — ahead of Michael Jordan — but had his career ruined by injuries. Oden has played just 82 games, the equivalent of one full season, since being drafted.
He remains immensely popular and unfailingly upbeat, even high-fiving teammates at halftime Saturday to encourage them.
Oden was just starting to get some traction. Before his injury, he had the best seven-game stretch of his career, averaging 15.6 points, 9.1 rebounds and 2.4 blocks, including a career-high 20-rebound effort against Miami.
"When he played well, we were a whole new team," Pritchard said. "And we thought he could get even more consistent and there was another level to be reached."
Nearly three-quarters of a season are still to be played without Oden, and the Blazers may have enough to make some noise in the playoffs. But greatness may have to wait until another season, another year, another moment, until Oden can stay on the court.
That much, the Blazers say, they are not worried about.
"The last thing I have is given up hope that he can be a better player than what we just saw," Pritchard said of Oden. "He knows that he's got even more left. That's more exciting than anything."Continue reading the main story