text:
What is a tessellation?
Tessellations are pattern of shapes that fit perfectly together.
Here are a few examples.
MC Escher
MC Escher is very famous for his tessellations and other math based art. What is interesting about Escher is that he never had any math training. He figured out how to create tessellations by looking and practicing. He failed many times before making perfect tessellations, but like any successful person, he was not afraid to fail and continued to try until he did it!
How do you make a tessellation?
For this project, we will be following step-by-step procedures, all at the same time, and checking each other's work frequently to make sure we make a successful tessellation. First, we will make a stencil from a square piece of paper.
Next, we will trace out stencil over an entire sheet of paper.
What does my shape look like?
After we've traced out our stencils, we will as ourselves, "what does my shape look like?" Does it look like an elephant? A dog? A face? Once you figure it out, draw that image in each of your shapes.
Last, we color it in!
YouTube Tutorial
This video demonstrates how we will be making our tessellations. Watch and listen closely.
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Gain access to an engaged audience, grow brand recognition, and support innovation.
Investment in FAILURE:LAB provides Sponsors with exposure to an attentive audience and media coverage. Our Sponsors are given credit throughout the entire event, are highlighted several times leading up to the event, and remain visible on the FAILURE:LAB website and videos on the website. Your name and brand live on long after the event. Benefits of being a FAILURE:LAB Sponsor include:
Access to an Engaged Audience
As a Sponsor, you have the eyes and ears of individuals who will notice and appreciate your brand in connection with a FAILURE:LAB event. It will bring your brand to crowds in a setting of openness and will showcase your company in a whole new light.
Brand Recognition
FAILURE:LAB recognizes all Sponsors as true partners and will go above and beyond to recognize and to promote your organization. Your logo and name will prominently appear on all promotional efforts leading up to an event, at the event, and your brand remains imprinted on the events page, Sponsor page, and other areas of our website.
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Not only do we appreciate your financial generosity, but we want you to experience first-hand what you are supporting. Your organization will receive FAILURE:LAB event tickets and we will send information about events happening in your region and around the globe. You will be apprised of every exciting initiative FAILURE:LAB brings to the public. Once you're a Sponsor, you're part of the FAILURE:LAB family.


text:
NevadaGrown Foods, Award-Winning Brews And Live Music At The Brewery
Great Basin Local Nevada Farmer's Market
SPARKS, Nev. – Great Basin Brewing Company in Sparks is celebrating Nevada's late-season harvests with a NevadaGrown farmers market that will feature local farms, ranches, food purveyors and artisans. The market will be held at 846 Victorian Ave., Sparks, from 3:30 – 7:30 p.m., every Thursday in September beginning Sept. 5.
Fresh produce, meat, cheese, artisan beer, bread and packaged foods are a few of the featured items, in addition to arts and crafts from local Nevada businesses. The Food Bank of Northern Nevada will host weekly raffles for market bucks along with its community food drive. The brewery will keep the celebration thriving into the evening with free live music on its outdoor stage, handcrafted local brews, and signature dishes using fresh, local ingredients.
The farmers market is a partnership between the Great Basin Brewing Company, NevadaGrown and the Food Bank of Northern Nevada to honor Nevada's farms, ranches and local independent businesses. For more information, call Ann Louhela, 775-351-2551.
About Great Basin Brewing Company
Great Basin Brewing Company, Nevada's oldest and most award-winning brewery, has two restaurant/ brewery locations in Reno and Sparks, Nevada. Great Basin also features a tasting room at the Taps and Tanks production brewery in Reno. The brewery offers a full menu and a wide variety of beers — four flagship beers and many seasonal brewmaster specials, many having won awards at the most prestigious Great American Beer Festival and the World Beer Cup. For more information about Great Basin Brewing Company, visit greatbasinbrewingco.com.


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According to iSupply, sales of widescreen LCD monitors are expected to leap 73.4 per cent worldwide by 2011. 9.1 million 16:9 screens were sold in 2006, but this could climb to 146.9 million by 2011, creating a market worth more than 20 billion dollars. iSupply believes the shift to widescreen PC monitors will begin in earnest this year, with more than 35 million screens sold before the end of 2007, with 19, 20 and 22-inch panels becoming increasingly competitive.
Huge boom in widescreen PC monitors predicted
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This is a simple console-based LAN chat program that must be accessed in a common network folder ( please make sure this folder is empty ) by all the users. It is a basic program and can be used for simple chats between LAN connected computer systems but has features to enable you to share links and files too.
You can check out installation instructions in the 'Files' tab.
Check the 'Changelogs' for changes made, 'Hacks' for hacks in the program, and 'FAQ' for any questions. They are all under the 'Wiki' tab.
Currently, the program only runs on Windows systems. It has not been tested on Linux systems that run windows executables using Wine or any other such emulator.
- Refreshes with new messages automatically
- Type at your own pace and not be limited by the refresh rate of the program.
- Allows sending links / network paths and files through separate sections within the chat
- Names of user chatting, names of users in message, links / network paths and dates and times of files are highlighted in various colours
- Shows if another person is typing
- Can scroll through messages, links / network paths sent and files sent list
- Clever check if users are present or not (if not, it will delete previous chat files and recreate new empty ones)
- Simplicity
- Console program
- Hacks to highlight words/phrases in various colors that are also used in the above mentioned feature
- Has support for systems which are not compatible with UNC directories
Other Useful Business Software
User Reviews
Be the first to post a review of CONSOLE CHAT PROGRAM!


text:
An optimally evolved connective ratio of neural networks that maximizes the occurrence of synchronized bursting behavior
Synchronized bursting activity (SBA) is a remarkable dynamical behavior in both
In this study, artificial pulsed neural networks were established using spike response models to capture fundamental dynamics of large scale
In a neural network, the evolutionarily selected CR (10-30%) optimizes the occurrence of SBA, and APFL serves a pivotal network motif required to maximize the occurrence of SBA.
In the brain development, neurons are assembled together via numerous synapses to build up complicated neuronal networks performing specific behaviors, such as transient or sporadic activity, synchronized bursting activity (SBA), and hyper-excitable activity. One of the most prominent behaviors in cortical networks is the synchronized bursting spikes occurring in the brain development and maturation
Although SBA is an unique phenomenon in neuronal networks, characteristics of the neural networks causing SBA remain unknown, in contrast to the study on the function significance of the SBA
According to the above described connectivity characteristics of
This study also explored the relationship between the occurrence of SBA and the composition of network motifs in the neural networks
For a pilot study in real neural networks, we have employed the neural network of nematode worm
The optimal CR at the maximal occurrence of SBA
To unravel the biological significance of the CR of matured neural networks (10-30%), we first investigated the relationships between CR, ER, and the occurrence of SBA. Spike response models (SRM) can be used to simulate random
The SBA properties of networks were investigated at two different scales: small networks with 12 nodes and large networks with 60 nodes. We recorded and calculated the expectation and standard deviation of SBA occurrence over the 1,000 networks (with a stereotyped CR and ER). Figure
Figure 1
The relationship between the occurrence of SBA and CR (or ER) for 12-node networks and 60-node networks
The relationship between the occurrence of SBA and CR (or ER) for 12-node networks and 60-node networks. (a-1), (a-2) The relationships among CR, ER, and the occurrence of SBA for 12-node networks from two different perspectives. The occurrence of SBA in 1,000 randomly connected networks was evaluated on each point of a lattice composed of CRs (0:0.05:1) and ERs (0:0.1:1). The surface points represent the mean value of the occurrence of SBA, while the upper and lower red bars show their standard deviations over 1,000 simulations. (a-3) The relationship between CR and the occurrence of SBA for 12-node networks when ER equals 0.9, which is consistent with the actual biological level. (b-1), (b-2) The relationship among CR, ER, and the occurrence of SBA for 60-node networks from two different perspectives. The occurrence of SBA in 1,000 randomly connected networks was evaluated on the same lattice as (a). The surface points represent the mean value of the occurrence of SBA, while the upper and lower red bars show their standard deviations over 1,000 simulations. (b-3) The relationship between CR and the occurrence of SBA for 60-node networks when ER equals 0.9 (the biological level).
The optimal number of APFLs causing maximal occurrence of SBA
The existence of APFLs was shown to be a prerequisite for inducing SBA for 2, 3, and 4-node pulsed neural networks
Figure 2
The relationship between the total number of 2, 3, and 4-node APFL motifs and the occurrence of SBA or HEA for the 12-node networks and 60-node networks
The relationship between the total number of 2, 3, and 4-node APFL motifs and the occurrence of SBA or HEA for the 12-node networks and 60-node networks. (a-1) The relationship between the total number of 2, 3, and 4-node APFL motifs and the occurrence of SBA for the 12-node pulsed neural networks. (a-2) The relationship between the total number of 2, 3, and 4-node APFL motifs and the occurrence of 2-channel HEA for the 12-node networks. (b-1) The relationship between the total number of 2, 3, and 4-node APFL motifs and the occurrence of SBA for the 60-node pulsed neural networks. (b-2) The relationship between the total number of 2, 3, 4-node APFL motifs and the occurrence of 2-channel HEA for the 60-node networks.
The relationship between the number of 2, 3, or 4-node APFLs and the occurrence of SBA
We also investigated the relationship between the distribution of each type of APFL and the level of SBA. In the 12-node neural networks, we found that 2-node APFLs are significantly enriched compared to 3-node or 4-node APFLs for all levels of SBA (Figure
Figure 3
The influence of 2, 3, or 4-node APFL motifs on inducing SBA
The influence of 2, 3, or 4-node APFL motifs on inducing SBA. (a-1) The number of 2, 3, or 4-node APFL motifs with respect to the level of SBA (12-node networks). (a-2) The occurrence of SBA along with the absence of particular APFL motifs or combinations of motifs in 12-node networks. (b-1) The number of 2, 3, or 4-node APFL motifs with respect to the level of SBA (60-node networks). (b-2) The occurrence of SBA along with the absence of particular APFL motifs or their combinations in 60-node networks.
How is SBA inhibited when each type of APFL motif is absent from the pulsed neural networks? Figure
A case study of the egg-laying circuit of
We investigated the egg-laying circuit of
Figure 4
The egg-laying circuit of
The egg-laying circuit of
We carried out simulations over two network groups for 20,000 times with different synaptic weight perturbations. One group of networks are randomly connected with any CR between 0 and 1, and the other group of networks have the same topological structure as shown in Figure
The present study unraveled the direction of neural network development to facilitate a relatively high level of SBA. Thus, the CR range of a mature cultured neural network may represent a delicate design and not the result of random selection. In addition, such biological interpretation of the optimal CR may be further applicable to
We showed that our main results are quite robust to variations of network scales, network topological properties, and simulation parameters. We carried out simulations (see Simulation protocols) for a variety of neural networks with 10-300 nodes and found that the mean value of all the optimal CRs is 13% (with a standard deviation 0.0181) which lies within the evolutionarily selected range of CR (10-30%). In addition, note that the networks used for simulations in the early part (1,000 networks were constructed for each CR and ER) were based on random connections and therefore various possible topological structures were already taken into account. So, we confirmed that our results hold regardless of particular connective forms. We have also investigated the possible influences by perturbation of parameters {
In this study, we investigated the underlying cause of the evolutionarily selected CRs of neural networks. Artificial pulsed neural network simulation has shown that an optimal CR range (10-30%) maximizes the occurrence of synchronized bursting behaviors (when ER = 0.9), which is consistent with previous
Employing time-series data from multi-electrode array experiments, we identified some APFL motifs in cultured cortical networks of E18 Sprague-Dawley rats
Furthermore, we investigated the distribution of each type of APFL motif (2, 3, or 4-node) at different SBA levels. In both 12-node and 60-node networks, the 2-node APFL motif dominated among APFL motifs at high SBA levels. More importantly, the contribution of each type of APFL motif to SBA was demonstrated by comparing the inhibitory effect of each APFL motif against SBA. For large-scale networks, the exclusion of 2-node APFLs almost fully prohibits the occurrence of SBA, implying that compared to other APFL motifs, 2-node APFL motifs may be crucial for neural networks to produce SBA.
Definitions of network motifs and feedback loops
A network motif is defined as an enriched sub-network pattern in complex networks that occurs more frequently than in randomized networks
A feedback loop (FBL) is defined as a network motif composed of network nodes (neurons) and closed directed paths (synapses). The example network shown in Figure
Figure 5
Illustration of feedback loops and APFLs
Illustration of feedback loops and APFLs. (a) An example network composed of five different feedback loops. An interaction between nodes is represented by arrows to denote excitatory regulation and blunt lines for inhibitory regulation. The sub-networks colored in red denote the two APFL motifs. (b) Five feedback loops (FBL) contained in the network shown in (a).
Pulsed neural networks
To infer the relationship between a type of feedback motif and its network behaviors, typical network motifs were constructed based on pulsed neural networks, and their network responses to randomly assigned initial states and simulation parameters were observed. The pulsed neural networks, also called the third generation of artificial neural networks, are based on spiking neurons, or "integrate-and-fire" neurons
For a spiking neuron
A pre-synaptic spike at time
The models described by (1)-(3) are referred to as SRMs
where the kernel function
Figure 6
The functions describing the dynamics of a spike neuron
The functions describing the dynamics of a spike neuron. (a) The kernel ε
where τ
One typical membrane voltage reset function is
Networks of different sizes can exhibit similar network behaviors (or dynamics) if their neurons are supplied with the same average inputs
The typical behaviors of spike neural networks
Four typical spontaneous network behaviors appeared during the simulations: transient response activity (TRA), SBA, asynchronized bursting activities (ASBA), and HEA
By its definition,
Figure 7
Four possible network behaviors for a 2-node PFL motif with various synaptic efficacies
Four possible network behaviors for a 2-node PFL motif with various synaptic efficacies. The initial state of the network is taken as (1,1). (a) The scheme of a 2-node PFL motif. (b) Transient response activity. (c) Synchronized bursting activity. (d) Asynchronized bursting activity. (e) Hyper-excitable activity.
Simulation protocols
Simulations were carried out using SRMs for the randomly connected networks where all neurons were assumed to have an identical parameter set {
To investigate the relationships among CR, ER, and the occurrence of SBA, simulations with both synaptic efficacies and network structures randomly perturbed were carried out using different combinations of CR and ER. Classification of four typical network behaviors (TRA, SBA, ASBA, and HEA) can be found in the section entitled "The typical behaviors of spike neural networks". For each ratio pair (CR, ER), 1,000 randomly connected artificial neural networks were constructed, and simulations based on these networks were carried out. For each constructed network (corresponding to one simulation), the total number of APFL motifs (2, 3, and 4-node) and the occurrences of
APFL: All-positive-interaction feedback loop; TRA: Transient response activities; SBA: Synchronized bursting activities; ASBA: Asynchronous bursting activities; HEA: Hyper-excitable activities; CR: Connective ratio; ER: Excitatory ratio; SI: Synchrony index; SRM: Spike response model.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
KHC designed the study, CYD performed the simulations, CYD and KHC analyzed the data, and CYD and KHC wrote the paper. All authors read and approved the final manuscript.
We thank Dongkwan Shin and Chaoxuan Dong for their critical reading of this paper. This work was supported by the National Re-search Foundation of Korea (NRF) grants funded by the Korea Government, the Ministry of Education, Science & Technology (MEST) (2009-0086964, 2010-0017662, and 2011-0006314). It was also supported by the WCU (World Class University) program (R32-2008-000-10218-0) through the NRF funded by MEST.
Cell type-specific synaptic dynamics of synchronized bursting in the juvenile CA3 rat hippocampus
Systematic analysis of synchronized oscillatory neuronal networks reveals an enrichment for coupled direct and indirect feedback motifs
Topology of biological networks and reliability of information processing
Spontaneous periodic synchronized bursting during formation of mature patterns of connections in cortical cultures
Stimulus-specific neuronal oscillations in orientation columns of cat visual cortex
Gamma (40-100 Hz) oscillation in the hippocampus of the behaving rat
Single-column thalamocortical network model exhibiting gamma oscillations, sleep spindles, and epileptogenic bursts
The role of neuronal synchronization in selective attention
Neuronal synchronization along the dorsal visual pathway reflects the focus of spatial attention
Dynamic predictions: oscillations and synchrony in top-down processing
Spike synchronization and rate modulation differentially involved in motor cortical function
Oscillatory responses in cat visual cortex exhibit inter-columnar synchronization which reflects global stimulus properties
Primary cortical representation of sounds by the coordination of action-potential timing
A design principle underlying the synchronization of oscillations in cellular systems
Frequency of synchronous oscillations of neuronal activity increases during development and is correlated to the number of synapses in cultured cortical neuron networks
Dual intracellular recording of neocortical neurons in a neuron-glia co-culture system
Simultaneous induction of pathway-specific Potentiation and depression in networks of cortical neurons
Development, learning and memory in large random networks of cortical neurons: lessons beyond anatomy
Activity-dependent development of the vertebrate nervous system
Observations and modeling of synchronized bursting in two-dimensional neural networks
Spike-timing dynamics of neuronal groups
Networks of spiking neurons: the third generation of neural network models
Cholinergic neurons in the rat cerebral cortex demonstrated by immunohistochemical localization of choline acetyltransferase
Primary culture of identified neurons from the visual cortex of postnatal rats
Synchronization properties of network motifs
Synchronization properties of network motifs: Influence of coupling delay and symmetry
Understanding the mind of a worm: hierarchical network structure underlying nervous system function in C. elegans
Specification of the nervous system
Collective dynamics of'small-world' networks
Structural Properties of the
Heterochronic mutants of the nematode Caenorhabditis elegans
Egg-laying defective mutants of the nematode Caenorhabditis elegans
On the Behrens-Fisher problem: a review
Intracellular [Cl-] modulates synchronous electrical activity in rat neocortical neurons in culture by way of GABAergic inputs
Coupled feedback loops form dynamic motifs of cellular networks
Evolutionary design principles and functional characteristics based on kingdom-specific network motifs
Quantitative analysis of robustness and fragility in biological networks based on feedback dynamics
Network motifs: simple building blocks of complex networks
Efficient discrimination of temporal patterns by motion-sensitive neurons in primate visual cortex
Speed of processing in the human visual system
Activity dynamics and propagation of synchronous spiking in locally connected random networks
Dynamics of networks of randomly connected excitatory and inhibitory spiking neurons
Dynamics of population rate codes in ensembles of neocortical neurons
Learning biological networks: from modules to dynamics
An approach to the quantitative analysis of electrophysiological data from single neurons
Temporal relations of the complex spike activity of Purkinje cell pairs in the vestibulocerebellum of rabbits


text:
There are many Jolley stores throughout Vermont, New Hampshire, and New York. Please pick the location you wish to know more about.
A locally owned petroleum products company located in Saint Albans Vermont. Delivering Gasoline and diesel to dealers in Vermont and New York.
A locally owned home heating fuel oil Company located in Saint Albans Vermont. Serving thousands of homes and farms in northwestern Vermont.


text:
Team notes
NL West
Arizona Diamondbacks
The Diamondbacks might have lost starter Brian Anderson
to the DL with a strained left groin suffered Saturday against San Diego. Anderson
pitched six scoreless innings before injuring the groin on a pitch to Ryan Klesko,
who grounded out to start the seventh.
Anderson already had a stint on the DL with a stiff lower
back earlier this year.
A likely candidate to come up from Triple-A Tucson would
be left-hander Nick Bierbrodt, who has been dominating Pacific Coast
League batters. Bierbrodt, the Diamondbacks' first-ever draft pick in 1996,
struck out 11 Iowa batters in eight innings of a 1-0 victory Saturday night
in Tucson. He is 2-0 with a 0.46 ERA in three Triple-A starts. He was 2-1 with
a 1.37 ERA at Double-A El Paso before that. Overall, Bierbrodt has given up
just three earned runs in 39 1/3 innings.
"If I come back and (tear it) again, that could be the
end of the season," Williams said.
Colorado Rockies
Colorado hopes that scoring four ninth-inning runs to beat
San Francisco 7-5 on Saturday ended a disturbing trend.
To that point, the Rockies had gone 4-12 in one- and two-run
games, a key reason they finished the week tied with San Diego and San Francisco
at the bottom of the NL West. They then exploded on the Giants for an 11-2 win
"We were falling in that trap where it seems like we can't
make the big pitch, can't get the big hit," said pitcher Denny Neagle,
who did not get a decision in the victory because the Rockies blew his 3-2 lead.
Neifi Perez celebrated his 26th birthday with a
two-run single off Robb Nen to tie the game, and Larry Walker won it
with his 18th homer, a two-run shot off Chad Zerbe.
When Hollandsworth fouled a pitch off his right shin May
11, he suffered bone, nerve and soft-tissue damage. There is no timetable for
his return.
"It's as if he broke the bone in that area of the leg without
actually breaking it," general manager Dan O'Dowd said, explaining a
specialist's findings. "We don't know yet if he'll be out as long as he would
if he had broken it."
Los Angeles Dodgers
Right-hander Kevin Brown was placed on the 15-day
disabled list Monday, retroactive to May 30, after an MRI exam showed no cervical
damage but inflammation at one of the nerve roots.
Brown had experienced pain and stiffness during his May
29 start against Colorado, in which he allowed a season-high six runs and five
walks. He informed the team he had slept on his neck wrong.
Brown has fought injuries throughout the season. He's been
bothered by an Achilles' tendon strain, bruises to his left elbow and left knee,
soreness in his back and a strained rib cage muscle.
He was 5-1 with a 1.09 ERA in his first seven starts, but
is 1-2 with a 7.16 ERA in his last three starts. He has had his starts pushed
back a day or two on numerous occasions to accommodate the physical toll on
his body.
Terry Adams was to take Brown's place in the rotation
Tuesday at Arizona, with infielder Chris Donnels coming off the DL.
While there is some disparity in the numbers, it isn't
enough to explain the extremes in the record. The Dodgers have averaged 4.4
runs per game at home and 4.7 on the road. Their ERA is 3.26 at home and 4.58
on the road.
"What we've done on the road, you can basically say it's
terrible," second baseman Mark Grudzielanek said. "We really need to
wake up and just forget about what's happened and look forward to tomorrow and
try to get better there."
Both are on the DL. Karros is bothered by a partially torn
ligament in his back and hasn't played since May 21. Sheffield has a torn ligament
in his left index finger and hasn't played since May 23. Through the weekend,
neither had picked up a bat.
San Diego Padres
Though he stopped short of announcing this will be his
final season, Tony Gwynn revealed his plans for the future no longer
involve playing. Gwynn wants to coach baseball at San Diego State University.
"It's a perfect fit," said Gwynn, who remains on the DL
with a hamstring strain. "Take what you've learned about baseball, and pass
it on. Teaching, that's what I love most."
The school announced 30-year coach Jim Dietz will return
for the 2002 season, then retire. Gwynn played for Dietz, and Gwynn's son, Anthony,
just completed his freshman season with the Division I Aztecs.
Through the club's first 56 games, Davis was hitting .293,
had a .404 on-base percentage and had thrown out 38.9% of runners attempting
to steal. He started all but four games in May.
"He's hitting; he's doing the job behind the plate," Bochy
said. "He's the player we expected all along."
"I've got bigger problems to worry about," said Gwynn.
Sterling Hitchcock had the same operation three
weeks earlier but suffered a setback because of a strained flexor tendon.
San Francisco Giants
Perhaps the most amazing thing about the Giants' 1-0 loss
in 18 innings to Arizona was that Benito Santiago, 36, caught all 18
innings. That was after he caught 12 innings the previous day.
"I'm not sore," Santiago said. "I got up at 9 o'clock (the
next day) to take my baby to the doctor. I feel great, man."
"It feels like someone stuck a knife in my chest," Snow
said. "It hurts me to breathe."
In two seasons with the Giants, Nathan was 12-6 with a
4.70 ERA. His velocity has been down since the operation.
In his last start for Fresno, Nathan allowed home runs
to four consecutive batters.


text:
Can ritilan and aderall be taken together?
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- 3 Sep 2014 by grncougar
- Active
- 3 Sep 2014
- Topics
- adderall, attention-deficit hyperactivity disorder (adhd), adult adhd
Responses (1)
Further Information
- Adderall Information for Consumers
- Adderall Information for Healthcare Professionals (includes dosage details)
- Side Effects of Adderall (detailed)
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text:
Panic! At The Disco
by: Lindsey Ward
The Early Years
-Panic! At The Disco was started in 2004 by Brent Wilson, Ryan Ross, Brendon Urie and Spencer Smith
-Started in Las Vegas
-Classified as alternative rock or emo-pop
-First signed to Decaydance Records after sending a demo online to Fall Out Boy's bassist Pete Wentz
Since their formation and first album release, both Ryan Ross and Brent Wilson have left the group
-The current band members are Brendon Urie, Spencer Smith and Dallon Weekes
Band Members
-Born April 12 1987 in Las Vegas NV
-Went to Palo Verde High School
-Joined Panic! in his senior year of high school
Brendon Urie
-Born September 2 1981 in Las Vegas NV
-Went to a Catholic High School in Summerlin NV
-went to the same high school as initial band mates Ryan Ross and Brent Wilson
Spencer Smith
-Born May 4 1981 in a small town in Missouri
-Attended Clearfield High School in CT
-Was picked up by the band after Ryan Ross and temporary guitarist Jon Walker left the band in 2009
Dallon Weekes
Greatest Successes
- won the MTV Video of the Year award in 2006 for "I Write Sins Not Tragedies"
- the single "I Write Sins Not Tragedies" made the Billboard Top 40
-single "Miss Jackson" made number 68 on the Billboard Top 100 within the first week of its release
Dont forget to close the god damn door!
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Panic! At The Disco
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Question: The area under the density curve that lies between 15
The area under the density curve that lies between 15 and 20 is 0.414. What percentage of all possible observations of the variable are either less than 15 or greater than 20?
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Answer to relevant QuestionsA variable is normally distributed with mean 68 and standard deviation 10. a. Determine and interpret the quartiles of the variable. b. Obtain and interpret the 99th percentile. c. Find the value that 85% of all possible ...As reported in Runner's World magazine, the times of the finishers in the New York City 10-km run are normally distributed with mean 61 minutes and standard deviation 9 minutes. a. Determine the percentage of finishers ...Explain how to use Table II to determine the area under the standard normal curve that lies a. To the left of a specified z-score b. To the right of a specified z-score c. Between two specified z-scores The WONDER database, maintained by the Centers for Disease Control and Prevention, provides a single point of access to a wide variety of reports and numeric public health data. From that database, we obtained the following ...The area under a density curve that lies between 5 and 6 is 0.728. What percentage of all possible observations of the variable are either less than 5 or greater than 6?
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Melbourne Airport named in World's Top Five
Feb 27, 2008
Melbourne Airport was named in the Top 5 for airports that handle between 15 and 25 million passengers, in the Airports Council International (ACI) Airport Service Quality Survey.
The survey interviewed nearly 200,000 passengers across the world and is the largest review of passengers' opinions of its kind, and is considered a key benchmark for airports worldwide.
The survey measures overall passenger experience at each airport on 34 different parameters, included key issues such as ease of access, courtesy/helpfulness of staff, terminal connection times and value for money. The survey is the largest of its kind and is undertaken on site, with the experience of travel through the airport fresh in the passenger's mind.
Melbourne Airport CEO Chris Woodruff said the survey was fantastic recognition for the 12,000-strong Melbourne Airport workforce.
"Key to the ACI result is the exceptional work by the whole Melbourne Airport team – from our customer service staff, the airlines, restaurants, shops and security team – to the behind-the-scenes staff, including border agencies. Their commitment to delivering outstanding service to passengers is a key reason for Melbourne being named in the Top 5," said Mr Woodruff.
The acknowledgment comes as Melbourne Airport begins work on the largest ever series of expansions of its international terminal (T2).
"This sort of recognition is timely – with our recently commenced expansions of T2 set to establish new Australian benchmarks in passenger experience come 2012," said Mr Woodruff.
The expansion program, which will add a combined total of 25,000m² of new space to T2 (International), will be undertaken through a series of individual projects at a combined total cost of over $330m. Victorians can take a tour of their future international terminal by visitingwww.melbourneairport.com.au/t2/.


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Topic: Rashi
Date: 24th July, 2016 Sunday
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Broadcast: 27/06/2000
Reporter: Craig McMurtrie
The Hen House of Mexican politics has been controlled for over 70 years by the tautologically named, the Party of Institutionalised Revolution, or PRI.At the presidential elections on the 2nd of July their hold on power may finally be broken by the towering figure of Vicente Fox.The six foot five former rancher and Coca Cola executive is currently ahead in the polls and last week, over half a million turned out for his rally in Mexico City.Nicknamed 'Bronco' or wild horse, he's an extraordinary maverick in the Mexican political scene; he's rude, arrogant and does not come from the political mainstream, yet he's gathering a powerful coalition of Greens, businessmen and intellectuals to mount the most serious challenge to the PRI in many years. They are worried and pulling out all the dirty tricks of vote-buying and patronage, especially in the countryside.Fox is clearly ahead in the cities and if he wins, promises a real revolution in the corruption and nepotism that has characterised the rule of the PRI. Emotions are running high in this country of 100 million people and there are no guarantees that either side will accept the result if it's close, as all the polls predict.US correspondent Craig McMurtrie gains extraordinary access to Vicente Fox on the campaign trail and asks what his victory would mean for this nation on the frontline between grinding poverty and the global market.
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Motel 6 Oak Harbor hotels are listed below. Search for cheap and discount Motel 6 hotel rates in Oak Harbor, WA for your upcoming individual or group travel. We list the best Motel 6 Oak Harbor hotels so you can review the Oak Harbor Motel 6 hotel list below to find the perfect place.
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The perfect spot for me, my husband, and our six month old lab puppy. The location is amazing! Private access to a gorgeous beach and located right between Newport and Depoe Bay. Otter Rock is a cute little spot on the coast and home to...More
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The Conservative government is re-introducing the Not Criminally Responsible Reform Act.
The proposed legislation has two principal provisions:
- 1. It would allow for psychiatric patients who have been judged not criminally responsible (NCR) for actions that would otherwise be considered criminal acts to be labelled "high risk" to delay or prevent their discharge from treatment;
- 2. It would allow for victims and their families to oppose the release of these patients and to be informed of their whereabouts when they are released.
Or, if you prefer the more formal and loaded language of Bill C-14 itself : "This enactment amends the mental disorder regime in the Criminal Code and the National Defence Act to specify that the paramount consideration in the decision-making process is the safety of the public and to create a scheme for finding that certain persons who have been found not criminally responsible on account of mental disorder are high-risk accused. It also enhances the involvement of victims in the regime and makes procedural and technical amendments."Report Typo/Error
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Senior Alex Pickell is one of two Online editors on the Tiger. Born and raised in Little Rock, she is a Madrigal and the secretary for Feminist Alliance at school. Alex enjoys spending time tweeting and baking foods she finds on Pinterest. Some of Alex's other hobbies include hanging out with friends, writing letters to pin pals, and laughing at memes. Her favorite food is ice cream and she would "marry it" if she could. After high school, Alex plans on attending college and eventually grad school. She also intends on traveling while learning about the diverse cultures of the world.
Alex Pickell, online editor
|Feb 24, 2017
Gallery: College, Career Fair (Story)
|Feb 22, 2017
District Decision Fuels Public Outcry (Story)
|Jan 26, 2017
Students React To Trump's First Week In Office (Story)
|Dec 12, 2016
Tiger Online Crossword Puzzle (Story)
|Nov 29, 2016
Young Artist Wins National PTA Award (Story)
|Nov 11, 2016
The Tiger Reflects On Presidential Election (Story)
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Students Share Opinions On Trump Win (Story)
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'Gilmore Girls' Coffee Shop Pops Up Downtown (Story)


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Home ground of the St George club, in Sydney's south. Some of the great players who graced this ground in grade cricket included Bill O'Reilly, Ray Lindwall, Arthur Morris and Sir Donald Bradman. Frequently used as the venue for New South Wales second eleven and colts matches. Entered the record books as host of one first-class match in September 1995 when South Africa's Western Province played New South Wales during a pre-season Australian tour.
(Rick Eyre, November 2000)
Sabina Park, Kingston, Jamaica
Mahinda Rajapaksa International Cricket Stadium, Sooriyawewa, Hambantota
Queen's Park Oval, Port of Spain, Trinidad
The Cooper Associates County Ground, Taunton
Sir Vivian Richards Stadium, North Sound, Antigua


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How to make nature crowns
Was this guide useful?
It's so easy to make beautiful nature crowns with anything you can collect on an autumn nature walk. Just follow the steps and wear it with pride.
Step 1:
Firstly cover your table with plenty of newspaper or a dust sheet
Step 2:
Measure the distance around your child's head
Step 3:
Cut a length of lining paper to create the headband for your crown
Step 4:
You can cut this to shape or keep it as a simple band
Step 5:
Secure the band using sticky tape
Step 6:
Decorate your band by sticking on lots of flowers, twigs, grasses and any other interesting natural goodies you can find using glue or sticky tape
Top tip:
- You may want to double the thickness of the paper depending on how big you want your crown


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Written on: 23/01/2011
Hi all,
I have the original S1 and it has been a great trolley, I am still on the original 18 hole battery, and it still makes 24 holes on my course 6200 yds, but I do condition it(run it flat) every couple of charges. I think the pot is just fading so will replace soon but this is just £10 direct from Motocaddy. As it has been so good I have just purchased a new S1 digital trolley for my son with a 36 hole battery, all being well they will runs for a few years yet.
Written on: 13/01/2012
Good news - I have just ordered a new S1 with Lithium battery (expensive) but hope it will also be satisfactory.
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Explore Careers - Job Market Report
Report Header
Description | Titles | Duties | Related Occupations
Licensed practical nurses provide nursing care usually under the direction of medical practitioners, registered nurses or other health team members. They are employed in hospitals, nursing homes, extended care facilities, rehabilitation centres, doctors' offices, clinics, companies, private homes and community health centres. Operating room technicians are included in this unit group.
Included Job Titles
operating room technician, licensed practical nurse (L.P.N.), registered nursing assistant (R.N.A.), graduate nursing assistant.
Job Duties
- Provide nursing services, within defined scope of practice, to patients based on patient assessment and care planning procedures
- Perform nursing interventions such as taking vital signs, applying aseptic techniques including sterile dressing, ensuring infection control, monitoring nutritional intake and conducting specimen collection
- Administer medication and observe and document therapeutic effects
- Provide pre-operative and post-operative personal and comfort care
- Monitor established respiratory therapy and intravenous therapy
- Monitor patients' progress, evaluate effectiveness of nursing interventions and consult with appropriate members of healthcare team
- Provide safety and health education to individuals and their families.
- Prepare patients for surgery by washing, shaving and sterilizing the patients' operative areas
- Assist in surgery by laying out instruments, setting up equipment, assisting surgical teams with gowns and gloves and passing instruments to surgeons
- Clean and sterilize the operating room and instruments.
Included Cities in Region | Service Canada Offices
Included Cities in this region
Red Deer, Blackfalds, Innisfail, Lacombe, Penhold, Ponoka, Rimbey, Sylvan Lake
The future forecast and current conditions for an occupation can vary based on location or due to changes in the economy, technology, or demand for a product or service.
Local Employment Potential Information
|Employment Potential
|Release Date
|Red Deer Region
|(3 of 3 stars)
For the 2016-2018 period, the employment outlook is expected to be good for Licensed practical nurses (NOC 3233) in the Red Deer region.
This outlook is the result of an analysis of a number of factors that influence employment prospects in this occupation. Some of the key findings are that:
- Employment growth is expected to be strong.
- A large number of people are expected to retire.
- This occupation has recently experienced low levels of unemployment.
Here are some key facts about Licensed practical nurses in the Red Deer region:
- Approximately 490 people work in this occupation.
- Licensed practical nurses mainly work in the following sectors:
- Ambulatory health care services and hospitals (NAICS 621-622): 60%
- Nursing and residential care facilities and social assistance (NAICS 623-624): 27%
- Provincial and territorial public administration (NAICS 912): 12%
- They fall into the following age groups:
- 15 to 24: 6% compared to 16% for all occupations
- 25 to 54: 71% compared to 66% for all occupations
- 55 years and over: 23% compared to 19% for all occupations
Local Labour Market NewsWeek of Apr 17 - Apr 21, 2017
- The Red Deer Regional Hospital has opened two new dedicated obstetrical operating rooms and a recovery area. Additional nursing, clinical and non-clinical staff have been hired for the $9.7M labour and delivery unit.
- The Government of Alberta has added $2.66M in funding for the new seniors lodge in Rimbey, bringing the total contribution to $15.96M. The facility is expected to open in September 2017.
- The Government of Alberta and Alberta Health Services are expanding services at the Sylvan Lake Community Health Centre. The centre will undergo renovations this spring, with the new facility opening in 2018.
- Date modified:


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Italy's capital is one of the great cities of Europe. It's a large, busy metropolis that lives in the here and now, yet there's no other place on earth where you'll encounter such powerful evocations of a long and spectacular past, from the Colosseum to St. Peter's. Indeed, more than Florence, more than Venice, Rome is Italy's treasure storehouse. Here, the ancient Romans originated what we now call Western Civilization; centuries later Michelangelo painted the Sistine Ceiling, Bernini sculpted baroque nymphs and naiads that still dance in marble fountains, and Fellini filmed La Dolce Vita. Today, ancient Rome rubs shoulders with the medieval, the modern runs into the Renaissance, and the result is the world's finest open-air museum.
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The U.N. has 5 permanent members. They are The United States, Russia, China, France, and England. One of these countries can veto any U.N. action. In 2007 China vetoed the U.N. resolution to stop the genocide in Darfur. China buys oil from the perpetrator Sudan.
The inability to raise capital keeps poor countries poor. In Egypt registering a lot on state land takes 15 years. A permit to build a house on former farm land takes 11 years to aquier. 92% of city dwellers and 83% of people in the countryside live on dead capital in Egypt. The dead capital in the world is worth more than 40 times all foreign aid sense 1945. To legally register a one man cake shop in Cairo takes 500 days to complete all government paperwork. It takes 30 minutes in the United States. In Zambia, 90% of workers are employed illegally. They are not registered. They have no Medicare or pensions.
Global Warming
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- 2045 8.9 billion people
- The population rate at which the population stays constant is 2.1
- In China one in four will be over 60 by 2020.
- Educated girls that are able to read have lower fertility rates.
- Fertility rate in desitute countries is 8.0.


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Manchester City 4-0 Aston Villa: Sergio Aguero nets double in City stroll
By Lewis Jones
Last Updated: 06/03/16 11:00am
Manchester City broke their run of three straight Premier League defeats with a convincing 4-0 victory over Aston Villa on Saturday.
Manuel Pellegrini's side have slipped off the pace in the title race but goals from Yaya Toure, Raheem Sterling and a double from Sergio Aguero moved them to within 10 points of league leaders Leicester City.
Aguero could also afford to spurn a penalty as he missed out on a hat-trick against a Villa side that mustered just two shots on goal and had 28 per cent possession.
The result means Villa plunge closer to relegation from the Premier League with Remi Garde's side now nine points from safety.
Wilfried Bony was handed his first start of 2016 as he partnered Aguero in attack as Pellegrini made three changes to his team that limped to a 3-0 defeat at Liverpool on Wednesday.
The pattern of the game was clear from the outset. Manchester City attacked, Aston Villa sat back.
Garde's team had 11 men behind the ball for large parts as City enjoyed 77 per cent possession in the first half, although they rarely looked capable of breaking through Villa's deep backline.
Aguero had an effort from eight yards tipped over from Brad Guzan on 10 minutes while Bony really should have buried a Gael Clichy cross four minutes later.
Villa mustered their first shot on goal on 26 minutes but it so nearly gave them an unlikely lead as Joe Hart had to be very alert to palm away a snappy Jordan Ayew effort.
The home fans were becoming a little frustrated with their side but any fears of a further Premier League slip-up were put to bed within three minutes of the restart.
Toure finished off a move instigated by Aguero with a cool finish that deflected past Guzan off Micah Richards.
The returning Richards, who played 179 games for City, was in the thick of the action again two minutes later as Aguero punished his mistake to make it 2-0.
A ball in behind the centre-back put him in all sorts of trouble and his sliding clearance came off Aguero and straight into the net.
The Argentine striker sensed blood and trebled City's lead on 60 minutes as Villa's defending descended into a farce.
Aguero sprung into life and played a fantastic one-two with Silva. With Richards standing and watching, Aguero raced past him and smashed the ball into the bottom corner.
Sterling replaced Bony on 62 minutes and took just four minutes to get on the scoresheet.
Jesus Navas raced away down the right and squared the ball across the box for Sterling to tap home from close range. The Villa defence just stood and watched.
Ciaran Clark fouled substitute Kelechi Iheanacho in the penalty area on 72 minutes but Aguero missed his chance for a treble by curling the effort from 12 yards against the post.
Soccer Saturday verdict - Matt Le Tissier
"There was a vast gulf between the two sides. Villa threatened once in the first half, had one shot, when they actually threw enough men forward to make a difference. But there was nothing else in that first half, it was literally attack versus defence and how it was 0-0 at half-time I'm not quite sure.
"You knew once the first goal went in there'd be a landslide. It came on 48 minutes and 18 minutes later it was 4-0 and it was game over. In the big games this season Man City haven't been doing it - that's the key test for them. I wouldn't rule them out of the title race just yet."
Player Ratings
Manchester City: Hart (7), Sagna (7), Kompany (7), Otamendi (7), Clichy (7), Toure (7), Fernandinho (7), Navas (7), Silva (7), Bony (5), Aguero (8)
Subs: M.Garcia (6), Sterling (7), Iheanacho (7)
Aston Villa: Guzan (6), Lescott (6), Richards (4), Clark (5), Veretout (5), Hutton (6), Cissokho (5), Westwood (5), Gueye (5), Agbonlahor (5), Ayew (6)
Subs: Bacuna (6), Sinclair (6), Gestede (6)
Man of the match: Sergio Aguero


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That's a Great Question
We receive hundreds of emails and calls every month from listeners asking about certain topics that we might not have covered on air. This morning we share and discuss as many as we can in our "Great Question" segment.
In the first segment, we check in with Doug Wakefield of Best Minds, Inc. to discuss the tension between the U.S., Russia, China and North Korea and how it might affect markets and the world economy.Read More


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Web service and reverse proxy with the speedy nginx
Static Content and Caching
With this basic setup working, the next step is for nginx to statically serve some images. This step will allow you to tune your back-end httpd processes for dynamic content serving. I'll also serve images with an expires header of 30 days, which will cut down on the number of requests a client needs to make for common images that rarely change. To accomplish this, add the following to your server context:
location ~* ^.+\.(jpg|jpeg|gif|png)$ { root /path/to/www; expires 30d; }
If you'd like to disable logging for images requests, add the following line to the configuration:
access_log off;
Next, nginx will gzip some output received from the httpd back-ends before sending it to the browser. The nginx server will only gzip certain content based on mime type and will completely disable gzip for some known-broken browsers. Add the code in Listing 3 to your server context.
Listing 3
gzip in nginx.conf
If you'd like to cache some of your dynamic content with nginx, you have two options; file based or memcached based. If you're considering using nginx to cache content, be careful how you cache content that differs based on whether a visitor is logged in or not. To enable the file-based cache, add the following to the http context in your configuration file:
proxy_cache_path /data/nginx/cache levels=1:2 keys_zone=one:10m;
The levels parameter sets the number of subdirectories for the cache, and the key and filename are an md5 of the proxyied URL, resulting in filenames similar to /data/nginx/cache/c/29/b7f54b2df7773722d382f4809d65029c.
With the cache path set in the http context, you can now setup your cache in the http, server, or location context. To cache all 200 and 302 responses for 30 minutes and all 404 responses for 5 minutes, add the following:
proxy_cache one; proxy_cache_valid 200 302 30m; proxy_cache_valid 404 5m;
If you'd prefer to use memcached for your cache, it's almost as easy (see Listing 4).
Listing 4
memcached nginx.conf
01 server { 02 location / { 03 set $memcached_key $uri; 04 memcached_pass name:11211; 05 default_type text/html; 06 error_page 404 @fallback; 07 } 08 09 location @fallback { 10 proxy_pass cluster; 11 } 12 }
Server Statistics
Many monitoring systems support the httpd mod_status module to gather and trend statistics. The stub_status module serves a similar role with nginx. This module is not compiled by default and must be enabled with the --with-http_stub_status_module configure argument. Once the module is compiled in, add the code in Listing 5 to your configuration file. An HTTP request to domain.com/nginx_status will return a plain text response in the format shown in Listing 6.
Listing 5
stub_status nginx.conf
01 location /nginx_status { 02 stub_status on; 03 access_log off; 04 allow TRUSTED.IP.ADDRESSES 05 deny all; 06 }
Listing 6
nginx_status output
01 Active connections: 291 02 server accepts handled requests 03 16630948 16630948 31070465 04 Reading: 6 Writing: 179 Waiting: 106 05 This server has 291 active connections, has accepted and handled 16630948 connections while serving 31070465 requests...
Additional Modules
The httpd mod_rewrite module is used by many sites. While nginx does have a rewrite module, its syntax is slightly different from the one for httpd. The nginx wiki has the full details [4].
One example of rewrite feature is a simple rewrite to enable SEO-friendly member pages:
rewrite ^/users/(.*)$ /user.php?user=$1? last;
A more complicated rewrite uses an if condition to redirect your visitors to a consistent domain:
if ($host ~* www\. (.*)) { set $host_without_ www $1; rewrite ^(.*)$ http://$host_ without_www$1 permanent; }
The GeoIP module creates variables based on the IP address of the client matched against the MaxMind GeoIP binary files. The nginx GeoIP module has two prerequisites – libGeoIP and the MaxMind GeoIP database(s). The latest libGeoIP is available from the MaxMind site [5], but keep in mind that many distributions have libGeoIP in their package repositories.
Add the following two lines to your http context to enable the GeoIP module.
geoip_country GeoIP.dat; geoip_city GeoLiteCity.dat;
You will now have the variables listed on http://wiki.nginx.org/NginxHttpGeoIPModule at your disposal. One common use case for the GeoIP module is to use the $geoip_country_code variable to send requests to different proxy upstreams based on country. If you'd like to pass the GeoIP information to you httpd back-ends, add the following to your proxy configuration:
proxy_set_header HTTP_GEO $geo;
Table 2 shows some additional nginx modules, along with a brief overview of their functionality.
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'Political correctness does not legislate tolerance; it only organizes hatred.'
Thanks to a reader, more on Barzun here.
I read 'From Dawn To Decadence' not long after it came out.
As posted, Barzun at The American Scholar-'The Cradle Of Modernism':
'For yet another cause of unhappiness was the encroachment of machine industry and its attendant uglification of town and country. The Romanticists had sung in an agrarian civilization; towns were for handiwork and commerce. Industry brought in not factories only, and railroads, but also the city — slums, crowds, a new type of filth, and shoddy goods, commonly known as "cheap and nasty." And when free public schools were forced on the nation by the needs of industry, a further curse was added: the daily paper, also cheap.'
Via C-SPAN-The Historical Context Of Allan Bloom…From Humanities: Why Nabokov's 'Speak, Memory' Still Speaks To Us


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2-Year Manfrotto Australia Warranty Standard shipping: $11.95
Fully-insured shipping: $15.95
Fully-insured shipping: $15.95
This Manfrotto Essential Camera Holster - Medium is a great transporter for your DSLR camera and lens. Its water-repellent treated rip-stop fabric makes it the perfect companion for any urban adventure. It holds and protects a DSLR with a superzoom lens (e.g. D5500 + 18-140mm). The internal pocket is located under the flap, making it easily accessible when the bag is open. It can either be carried as a holster on your belt or as a shoulder bag with the detachable shoulder strap.
- Water-repellent bag for your everyday photo adventures
- Perfect size for a DSLR with a superzoom lens
- Internal pocket for batteries & media cards
- Can also be used as a shoulder bag
- Top handle for easy carrying
|External Dimensions (H x L x W)
|25 x 16 x 14cm
|Internal Dimensions (H x L x W)
|23 x 14 x 12cm
|0.260 kg


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Breast cancer
Every year around 50,000 new cases of breast cancer are diagnosed in the UK. Five out of six women with breast cancer in England and Wales survive for at least five years; however, around 1,000 UK women still die of breast cancer every month. Our research is aiming to increase the survival rate through…
Large-scale population studies to determine which genes are responsible for causing breast cancer,
Genetic barcoding to identify different cancer types and to help develop specific treatments,
Clinical trials to test new treatments on patients.
A major research project analysing the genetic barcodes of 2,000 breast cancer samples has identified 10 different types of breast cancer. Each has a different survival rate and requires a different course of treatment. The results of this research are being used to develop new tests to diagnose different breast cancer types, which will then enable each patient to be given the most effective course of treatment. Cambridge is also helping to unravel the full genetic sequence for breast cancer, as part of an international initiative to identify the genetic blueprint of 50 cancers.
The Cambridge Breast Cancer Research Unit has collected over 20,000 tumour samples from breast cancer patients. This large diverse collection of tissue samples will be essential in the development and testing of new ways to diagnose the different types of breast cancer.
Cambridge has established a 'one-stop' clinic, the Cambridge Breast Unit, for rapid diagnosis of breast cancer. The diagnostic accuracy of the triple assessment (clinical examination, imaging and biopsy) is 99.6%. Nine-year survival rates of breast cancer patients treated at Addenbrookes Hospital is 84%, compared with a regional average of 78%. Around half of patients diagnosed with breast cancer at the clinic enter a clinical trial run by the Cambridge Breast Cancer Research Unit. Find out more about the Cambridge Breast Unit.
Researchers in Cambridge have identified how the oestrogen receptor-cistrome in primary tumours modulates response to hormone therapy. They demonstrated differential oestrogen receptor (ER) binding events in primary breast cancer (a first ever) and revealed a role for the pioneer factor FoxA1 as a crucial ER regulatory protein in drug resistant contexts, providing the impetus to develop therapeutic FoxA1 inhibitors.
Repeat biopsies to study genomic evolution as a result of therapy are difficult, invasive and may be confounded by intra-tumour heterogeneity. We have demonstrated the clear advantages of using circulating tumour DNA (ctDNA) over other tests as a biomarker for monitoring treatment response and disease progression in patients with metastatic disease. Specifically, we have developed a new approach, sequencing of cancer exomes in plasma, to study a series of patients who have developed resistance to chemotherapy, hormone therapy and Trastuzumab, with the aim of identifying potential causing mutations.
Visiting Professor
The CRUK Cambridge Centre Breast Cancer Programme is delighted to welcome Dr Nancy Davidson, AACR President, as Visiting Professor on 20-21 September 2017. Dr Davidson will be giving a lecture at the CRUK Cambridge Institute lecture theatre on Wednesday 20 September from 13.00-14.00 and will also be available for individual meetings.
Breast Cancer Programme Annual Retreat
The Breast Cancer Programme 2017 Annual Retreat will take place on Monday 2 October, at The Cambridge Building, Babraham Research Campus, CB22 3AT.
The draft programme for the day is here.
All members of the Breast Programme are invited to submit an abstract and register here. Abtracts should be 300 words, most will be selected for posters but two will be selected for oral presentations. Places are limited so please sign up soon. The deadline for abstract submission is Monday 4 September and the deadline for registration is Monday 18 September.


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Our original inspiration and the VERY FIRST SEASALT GARMENT, now in its 35th year.
We make our striped tops with the FINEST QUALITY ORGANIC COTTON & design them in lots of lovely colours.
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Made famous over the years by the likes of BRIGITTE BARDOT, PABLO PICASSO and JOE the BOATMAN on the Isles of Scilly.
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Seasalt - a Cornish fashion company. Women's clothing, footwear and accessories inspired by the creative and maritime heritage of Cornwall.
Registered Office: Unit 8 Falmouth Business Park, Bickland Water Road, Falmouth, Cornwall TR11 4SZ © Seasalt Limited 2005-2016.
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Believe it or not, we are slowly entering the festive season! This year we decided to run our festive promotions from November, so that you can get a head start on your Christmas shopping.
View their ranges:
- Lamelle Luminesce
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About Us
To establish a financial institution that is Christ centered and member focused.
Mission Statement
None Suffer Lack Federal Credit Union is a financial institution, operating as a ministry of excellence, where the people of God can network their resources together in a manner that will glorify God, maximize and strengthen what we have, and invest in the next generation.
To provide the body of Christ with sufficiency, independence, and control over their financial resources so that None Suffer Lack.


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Cintsa, or Chintsa as it's alternatively known, is a small beach settlement just outside of East London in the Eastern Cape. The distance is roughly 38 kilometres and the town can be reached in about 30 minutes. The beach town is notable as the so-called starting point of the Eastern Cape's famous Wild Coast. In this respect, Cintsa offers the best of both worlds as the wild and beautiful wilderness is a stone's throw away from the city and its reassuring infrastructure.
The Wild Coast is popular among adventure seekers, as not only is the landscape reflected in the name, providing endless, dare-devilish activities, but the rural isiXhosa villages dotted across the hills provide an eye-opening cultural experience for those who consider themselves discerning travellers.
Among the attractions in Cintsa are the long sandy stretches of beach, the tea-coloured river which enters the ocean just below the town, the lagoons, the forested dunes and the multitude of activities that these landscapes enable. Surfing, for example, is a particularly popular past time for both Cintsa visitors and locals, not least because the Indian Ocean is deliriously warm. One can also partake in a mountain biking tour which takes you up over the hills behind the town through a number of small isiXhosa villages and back along the beach.
The beach is a major point of interest, and the mild weather combined with soft clean sand and temperate waters makes it the perfect location for basking in the sun with a good book. Fishing and horse-riding are other optional activities for the outdoorsman, and when the sun starts to set, there are a number of charmingly rustic bars and-restaurants where a sundowner and snacks can be enjoyed A stay inCintsa is geared toward guests on a budget. There are a number of self-catering establishments. For those who like the taste of the higher life, semi-luxury hotels can be found in the area.
Sandy Burmeister won a booking to the value of R1400 at Lemon Tree Lodge
This was a lovely,unexpected surprise as you tend to always think that there is a catch to receiving your money back in full for your accommodation paid. The service received from Sleeping Out was professional and prompt and I will definitely use them again when I book accommodation. Thank you Sleeping Out!
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Luxurious apartments in Cintsa East, a superb coastal town. This tranquil piece of paradise to renew your soul. Each unit is fully equipped and tastefully decorated and fitted for your comfort. The un... Read More
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Pebbles and Shells is a unique private self catering apartment overlooking the Cintsa River within 10 min walking distance from the beach, the local shopping area and restaurants. The apartment offer... Read More
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Crawford's Beach Lodge, set along the magical Wild Coast, offers rustic luxury accommodation for the most discerning of travellers and conference organisers, who are looking for privacy, peace and tra... Read More
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This Luxury Double Story Guest House is located 500m from the beach on the Wild Coast of South Africa. It's elegantly decorated and fully equipped for all your needs. Wake up to the sounds of the Ocea... Read More
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Prana Lodge Private Beach Estate and Spa nestles on the Eastern Cape Wild Coast in a pristine dune forest right on Chintsa Bay. An easy 40 minute drive from the East London airport delivers you to a ... Read More
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We offer a beautiful and luxury house for all your holiday needs which overlooks the Glen Eden River. The house can accommodate up to 10 guests comfortably in 4 Bedrooms. The house encompasses a stunn... Read More
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Thistle Doo is situated in Chinsta at the start of the beautiful, unspoilt Wild Coast. With over 13km of sandy beach, fishing, horse riding, birding, hiking and Strandloper caves, Thistle Doo is ideal... Read More
From R2000* unit
The Seaside is a beautiful, sea front, self-catering holiday home, with magnificent views, ideally located in Cintsa East, on the Wild Coast of the Eastern Cape. It has its own private pathway down to... Read More
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From R3900* unit
The Beach House is situated a mere 100 m from Queensberry Bay Beach, nestled behind the dunes and coastal forest reserve. The Beach House offers its residents an extremely sheltered and private outloo... Read More
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Glengarriff Lodge, situated just 25 km from East London, at the southern end of the Wild Coast, offers unsurpassed business and holiday accommodation.
Nestled in the lee of the dune, only 50 paces ... Read More
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Price Range comparison
In order to provide meaningful price comparisons this website compares the Per Person Sharing Rate or, where this is not available, the Average Price Per Person for a unit, based on its maximum occupancy.When Homes and Villas are selected as the search criteria, the full daily rate for the unit is used for price comparison and display irrespective of the number of people the unit sleeps.* This accommodation is only available as a unit. It has been included in these search results as the average price per person based on maximum occupancy falls within the selected price range. However, the price displayed is the full unit price.
East London
Cintsa Accommodation has been rated 4.5/5 based on 9 reviews.
CintsaStunning and unspoiled town. Best kept secret in South Africa. - Cathy Van Den Heever
CintsaCintsa is very peaceful little village. Would go back - Charmaine Henriksen
CintsaWe loved Cintsa. The beaches were absolutely lovely, uncrowded with a fairly calm sea. The lagoons provided many hours of fun for the kids. Loved the relaxed atmosphere and we were blessed with exceptional weather ! Will definately visit again. - Kim Kavonic
CintsaA beautiful place with unspoilt, safe, clean beaches. Lovely little town for a family to visit and youngsters to get together. Made new friends at the Barefoot Cafe whilst watching the rugby. Unfortunately SA lost but spirits were high! A memorable experience! - Julia van der Merwe


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The announcement was met by scenes of jubilation in Argentina.
As the International Olympic Committee announced that Tokyo had been chosen to host the 2020 Games ahead of Istanbul and Madrid, the city's delegation jumped to their feet.
Many, overcome with emotion after two years of intense lobbying, wept.
Japanese Prime Minister Shinzo Abe, who had allayed fears over the crippled Fukushima nuclear plant, could not hide his delight. He said:
'It has been a long and difficult competition and I would like to salute all sportsmen (and women) as well as the Governor of Tokyo and the active athletes, for their support to win the bid to host the Olympic games. Without their efforts we would not have been able to win.'
The joy was just as obvious in Tokyo when residents awoke to the news.
The decision means Tokyo will become the first Asian city to host the Games twice, while Istanbul and Madrid go home empty handed again.


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Gold Covered NES
This original Nintendo entertainment system received a makeover by an old-school gamer. What he gave to this console picked up from the thrift store was a paint-job in the shades of gold and copper, making it look like an exquisite furniture piece. Now if some real metal was plated onto this device it will definitely attract a fair bit of real gold on eBay.


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Note : Your Quotation Request will be directed to Mini Circuits.
The MAR-8SM from Mini Circuits is a RF Amplifier with Frequency 0 to 1000 MHz, Gain 22.5 dB, Noise Figure 3.3 dB, P1dB 12.5 dBm, P1dB 0.0178 W. More details for MAR-8SM can be seen below.
1350 to 1390 MHz, 25 W Bi-Directional Amplifier
You can now find similar products from multiple companies on everything RF.


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The new DSPOT Series offers a full line of Digital Signal Processors. These processors allow the user to manage and clarify the sound produced in their speaker system. Each model can be accessed by the front panel or the convenient, easy to use, included software.
User defined presets provide a useful tool to live sound, where a preset can be used for frequently visited venues or specific performers in a fixed install. Presets can be also be saved to internal or removable drives, in addition to the device itself, allowing for a preset to be designed in advance, and then downloaded on site.
The DSPOT software provides many filtering and other detailed settings easily controlled on your PC, to refine your sound. All DSPOTs are perfect for fixed and live applications.
The DS-CP22 is a digital compressor with built in Noise Gate, Gain control, Automatic Gain Control (AGC), EQ, Sub Harmonic Synthesizer, Compressor, and Limiter. The DS-CP22 provides both Limiter and Compressor activity for both output channels.
Two great included features are the AGC and Sub Harmonic Synthesizer. The AGC allows you to set a target output level and the circuit will raise or lower the level to meet that target. The Sub Harmonic Synthesizer allows you to create either a deep very low body or a lighter and more booming extra body to the original sound.
The DS-CP22 provides 7 bands of parametric equalization with High/Low Pass filtering. Each EQ filter can be easily adjusted to a specific frequency, and the Q selected with simple Bell curve adjustments from 0.05-3.00. The DS-CP22 can store up to 32 presets.
Whether traveling on the road with the band or in a fixed installation, the DS-CP22 has the features needed to aid in sound improvement.
30 Days
Galaxy Audio products are warranted to the original purchaser for a period of 3 years (except check mate and anyspot which are waranteed for 1 year) against any defects in manufacturer's workmanship and materials.


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I can't stop smiling! The amount of fun that is being had in this video is too much for my heart to witness! The comments section is BUZZING with hype over King Kotini's dancing! Remember that time he showed us his pantsula while in studio? We'll pull out the file
Tag: #Umgulukudu
Total 4 Posts
Oh gahd it's Major League! And they're bringing us visuals to their smash featuring DaKAR and Cassper Nyovest. If you recall, we reported earlier this month for you to expect the music video for Umgulukudu - S'getit "soon". This Friday they drop it for the people on Channel O's Turn
The boys just shot the visuals for the smash #Umgulukudu - S'getit which features Cassper Nyovest and Kwesta. The boys took to Alexandra to shoot the video and judging from the stills shared on the TL's, it's going to be a great resemblance of the track which exudes the ghetto
This 👏🏾 track 👏🏾 has 👏🏾 all 👏🏾 the 👏🏾 Kwaito 👏🏾 flavour !! I won't lie, it took me back a bit. Cassper on the chorus sounds like he was having mad fun being all ratchet in the studio while recording. And well ... it's not like we don't know that Kwesta's voice is THE voice, but