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About Pier Uno Resort
Pier Uno Resort & Dive Center was formerly known as Tanya's Dive University, a family owned resort. It started as a rest house for the Crisostomo's family and friends of the family but open to public in November 2005 with 8 Casitas Deluxe, 5 Alexandria Superior and 3 Executive rooms & 6 Kubo rooms. To date, there are total of 30 rooms and a conference room that can hold up to 70 persons in a function.
The resort is situated at Anilao Batangas, it is the name of two Philippine Barangays: Anilao Proper & Anilao East. Both are located in the municipality of Mabini Batangas which is south of Manila on the large island of Luzon. The place was originally known as "Janao – Janao" and is said to be derived from the geographical shape and feature of the land and water comprising the barrio, palm tress resembling the Anahaw tree that serve as cool resting place for foot travelers going to and coming from the mother town; Bauan.
Anilao Batangas is two to three hours away from the busy street of Metro Manila with the new constructed highway and it is a popular place for divers and snorkelers over the weekends. The water surrounding the area is teeming with marine life with plenty of corals and amazing diversity of fishes.
The resort is accredited by Department of Tourism and is also a member of the Philippines Commissioned For Sports Scuba Diving. We are also accredited center of SDI and SSI and soon with PADI. We are committed to provide unforgettable experience, excitement and exploration in an exotic environment. The Philosophy of the company is to ensure guests receives the greatest value for money without the sacrifice of safety, comfort and enjoyment. IT's more fun in the Philippines but is even more fun diving and staying with Pier Uno Resort Anilao Batangas, always make us YOUR NUMBER 1 CHOICE !
Why Pier Uno Resort & Dive Center???
- More Than 20 Years Of Diving Experience With Over 8000 Logged Dives.
- More Than 15 Years Of Teaching Experience And Trained More Than 3000 Students Of All Levels.
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- Pay Less & Expect More.
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- Accredited By DEPARTMENT OF TOURISM PHILIPPINES.
- Accredited By PHILIPPINE COMMISSION ON THE PROMOTION & DEVELOPMENT OF SPORTS SCUBA DIVING.

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Sabrina Moor – Classy Sabrina
Released: August 14, 2014
Sabrina arrives in some very nice packaging – nice denim shorts, black pantyhose, elegant stilettos, and a white knotted top. Variety is one of Sabrina's strengths, as she mixes it up heavily in the first part of her video. She pees twice still in her shorts in two different poses. Things start getting more primal as she slides off her shorts. Sabrina backs up onto the table on her knees as we take a closer look from behind as she pees through her pantyhose. She escalates things further as she tears a hole in her pantyhose, liberating herself, as she spreads her legs apart like a bird's wings and pees again. Although there's never a massive outburst from Sabrina like her shoot for Wet and Puffy, there's an impressive amount of positions that she pees from. The abundance of poses coupled with her great looks were well worth our time.


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|Reviews for The Gate of Orion
| irezel chapter 1 . 1/25/2012
3 very nice. bit angsty, but that's what i love.
| Imperial Bob chapter 1 . 7/5/2010
Nice oneshot.
| Algazoth chapter 1 . 6/9/2010
Quite nicely done. You managed to stay true to both fandoms too.
| Takami-Heru chapter 1 . 5/30/2010
continue this
it was getting good T_T
| Kelspook chapter 1 . 2/15/2010
I really liked this, makes sense that the Doctor would crash into SG-1 at some point... But also that he wouldn't want to hang about with all those guns! lovely interaction, didn't feel forced at all. Spot on :)
| darkdranzer chapter 1 . 12/7/2009
wow. short drabbleish but really nice. i like how you had the time lords and the ancients as "allies to the end of time" that would really actually fit nicely. lol.
| hajimebassaidai chapter 1 . 11/23/2009
Brilliant. Quiet, understated and brilliant. I always love the character driven one shots where there aren't many events, just great writing! Also both Stargate & the Doctor are bang on which is often hard in crossovers to get the tone right. I hope you go on to do more in the future!
| Srebrna chapter 1 . 8/20/2009
Nice :) Doctor in his kinder (less rude) mode and meeting only Daniel. I really liked it :)
| msdarque chapter 1 . 7/11/2009
Lovely story! Congrats! I greatly enjoyed reading it.
| 123-321 chapter 1 . 4/24/2009
cute story!
| WalkInEternity chapter 1 . 3/23/2009
Great story. Loved how you combined the series.
| lenora chapter 1 . 11/5/2008
god, I loved it!
write more, please...
| heartfallen chapter 1 . 12/4/2007
Neat story!
| HelenaHermione chapter 1 . 4/10/2007
Oh, now that's a good story, the Doctor and Daniel sharing such a peaceful moment together, two fellows with the same mindset about life, the universe, and everything.
| Spoofmaster chapter 1 . 4/3/2007
Ah! Finally! A good DW/SG1 crossover!
Usually I don't dig it when folks have the Doctor start telling strangers all abut himself, but you kept it enigmatic enough that it really worked here. These two series have just been begging to be crossed over, and I guess they have been a good deal, but this is the first really good one I've seen. I'd add this to my Doctor Who C2, but I can't because of the category. Ah well, I can at least favorite it.


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Do you have any old textbooks you can part with? Between 1996 and 2001, factions of the Taliban in Afghanistan destroyed medical texts and reference materials because they considered anatomical depictions of the human body to be blasphemous. Since then, many doctors and medical students there have been practicing and learning medicine without them.
Operation Medical Libraries was formed in 2007, when an Army officer wrote the director of the Medical Alumni Association at the University of California, Los Angeles, asking for medical books. The director forwarded the request on to alumni, who forwarded it to colleagues and former classmates. The first shipment included 2,000 books.
Books have continued to pour in, and the organization has sent a total of 27,000 from its Los Angeles office. Many more have been donated directly to the overseas addresses posted on the website.
Most of the books are sent to Afghanistan, but the current address list is also seeking books for a biomedical library in Antigua and a facial trauma library in Germany for surgeons operating on American and Coalition soldiers.
Medical texts, including medical and technical dictionaries, and basic science and anatomy books published in the last five years are most desired. Overseas medical professionals also need scrubs, microscopes, stethoscopes and visual aids.
Visit Operation Medical Libraries here to read more and learn how to donate. Read a New York Times story about the project here.


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Highlight of the early May weekend stay in Banff was the Wolf Condos accomodations. From the floor plan, decor, furniture, amenities and cool wolf prints, it really felt like a home away from home and really wanted to stay longer. Loved the fireplace and firewood delivered to the door. The resort staff was quick to help, courteous and professional. Since the weather was so amazing that weekend, I asked to have dinner on the sun deck outside the resort lobby. The steak sandwich from their onsite restaurant Peppers was tasty. Didn't have time to check out the other amenities however they were popular with the other guests. I prefer to stay away from crowds, so I enjoy the fact the resort is located on the way into town and away from Banff Avenue traffic. Only minus for some folks might be climbing stairs and some rough sidewalks if mobility is an issue. On your next trip to Banff, take the opportunity to check out Banff Rocky Mountain Resort and ask for Wolf Condos availability; it was a comfortable and relaxing stay. I will definitely return!
- Official Description (provided by the hotel):
- Discover the meaning of a mountain getaway at Banff Rocky Mountain Resort, a relaxing retreat in the heart of Banff National Park. Ideally set amid eight acres of private parkland and surrounded by the glorious scenery of Canada's oldest national park, while just minutes from downtown Banff, the Banff Rocky Mountain Resort's breathtaking location and extensive amenities are certain to provide a casual and memorable stay in the Canadian Rockies. Indoor 15m swimming pool • Indoor and Outdoor hot tub • 171 well appointed rooms with configurations to suit everyone • Mountain Health and Fitness Club with full gym, sauna and massage therapy • Tennis and squash courts • Onsite Laundry Facilities • Free parking and wired or wireless internet access • Complimentary shuttle to downtown Banff. ... more less
- Reservation Options:
- TripAdvisor is proud to partner with Booking.com, Orbitz, Expedia, Hotels.com, Travelocity, Cheap Tickets, Priceline, TripOnline SA, Cancelon, getaroom.com, Hotwire, HotelQuickly and Evoline ltd so you can book your Banff Rocky Mountain Resort reservations with confidence. We help millions of travelers each month to find the perfect hotel for both vacation and business trips, always with the best discounts and special offers.
- Also Known As:
- Banff Rocky Mountain Hotel Banff


text:
3 x 4 A4 Interior Lockable Portrait Noticeboard, 1050 x 960mm
Item #: WW-297624028
Brand Resist-a-Flame
Not yet rated.Be the first to Write a Review
Ex VAT £340.83 Ex VAT Each
Vendor will ship goods directly to you within 11 to 15 days ((More Info))
Product Highlights
- Board Type: Noticeboards
- Length: 1050 mm
- Size: 1050 x 960mm
- The Shield® Resist-a-Flame® Interior Lockable Portrait Noticeboard features a fire-resistant cover and pinning surface that can be used to display information along hallways.
- Ideal for use in corridors and public places, this fabric noticeboard comes with a sturdy cover that safeguards any displayed materials against external damage. Equipped with dual locks, this board makes it difficult for unauthorised individuals from tampering with your material. It also prevents your literature from getting misplaced in case any of it comes loose. This easy-to-mount noticeboard comes with concealed brackets, giving it a neat finish. It has been designed to house 12, A4-sized sheets placed side-by-side and in portrait mode. Its woven, cloth surface makes it easy to pin up legal notices, articles or other important, business-related literature.
- Fire-resistant notice board
- Sturdy, see-through cover
- Dual-lock security
- 2 support stays
- Can accommodate up to 12, vertical, A4-sized sheets
- Easy to mount
- Concealed mounting brackets
- Dimensions: 1050 x 1012 mm (H x W)
|Board Type : Noticeboards
|Length : 1050 mm
|Size : 1050 x 960mm
|Height : 960 mm
|Brands : Resist-a-Flame


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Scotch - Single Malt
This bottle is currently not available through Proof66.
Glenfiddich Cask of Dreams Single Malt Scotch Whisky
Bottle/Rating Data
Tier/Percentile : Tier 1Proof66 Rating : 534 / 774Rabble Rating : 4.0 / 5.0Type: Single Malt ScotchProducer: Glenfiddich DistilleryOwner: William Grant and SonsWebsite: http://www.glenfiddich.com/ABV: 48.8% Proof: 97.6Price (USD) : $99Age: 14
San Francisco WSC
- 2012
Beverage Testing Institute
- This bottle has not been rated by this competition.
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- This bottle has not been rated by this competition.
Proof66 Notes
The Glenfiddich Cask of Dreams is a limited edition scotch is a blend of scotch no less than 14 years old (though some will be older). These were finished in 11 American Oak casks where, on a tour, real individuals wrote their dreams and signed their names on the outside of the actual barrel. Thus, the "cask of dreams." It is meant to commemorate their 125th anniversary as a distillery.
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This bottle has 1 rating and 1 review.
Wuli27 (63)
Rating: 4.0 (2014-03-10)
more than good, but no Snow Phoenix...
Rating: 4.0 (2014-03-10)
more than good, but no Snow Phoenix...
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Quick Click Hosting provides high quality OpenVZ Unmetered VPS of most sizes. We manage a big quantity of servers, with a large number of happy clients and several locations.
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INDIANAPOLIS (AP) After nearly 25 years aloft, the RCA Dome's roof will be coming down.
Officials announced Friday that the 16 large fans that keep the roof inflated will be turned off on Sept. 24. Once that happens, the fabric roof will sink into the stadium within 30 to 45 minutes.
A ceremony will feature former Mayor Bill Hudnut - during whose administration the stadium was built - flipping the switch. The roof will be cut into pieces and sold as memorabilia.
The dome opened in 1984. It was the Indianapolis Colts' home until August, when the new Lucas Oil Stadium opened nearby.
The implosion of the stadium has been planned for December.
The Associated Press
Guidelines: You share in the USA TODAY community, so please keep your comments smart and civil. Don't attack other readers personally, and keep your language decent. Use the "Report Abuse" button to make a difference. Read more.


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The Kadalekai Parishe is an annual groundnut fair held in Bangalore. It is a two-day fair that is done near Dodda Ganesha Temple in Basavanagudi. The place is chosen for the fair because Basavanagudi was one of the major producers of groundnut.
Vijaykumar M
Tell us what do you think of Mahendragarh
Travel Talk
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- My Favourite 51
- Been There 48
- Will Plan 50
- Will Avoid 17
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A part from the groundnut stalls, the other items that are displayed in stalls here include mehendi tattoos, glass dolls, trinkets, bangles, etc. along with stalls of local food items like bajji and bonda. It is celebrated on the last Monday of Karthika month.


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Washington Regional Gala to Honor Leadership, Vision, and Growth.
The Washington Regional Gala is set for 6 p.m., Saturday, July 15, at the recently expanded Walton Arts Center. Attendees can expect a lively program that features unique performances and also spotlights exceptional healthcare leadership.
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Sitter in Grande Prairie
Iam a 47 years old filipina and looking to babysit in my own home .My home is very clean and quit.Looking for either short or long term. Child would need to be droped off and picked up.
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|Roses are Dead, Violets are Few
| Belle of the Ball
|Erupt & Corrupt
|The Scooby Doo Adventures
|Written By
|Additional Characters
|→ LeShawna
→ Rose
→ Felice
→ Glen
Roses are Dead, Violets are Few is the eighth episode of season 1 in the The Scooby Doo Adventures.
Whilst in New York City, Daphne bumps into an old friend from college who has a terrifying problem involving a big bug. Will the gang solve the mystery?
The gang are seen getting off a coach after a long distance trip. It is soon made apparent that they're in New York City after a conversation within the gang with several mentions to nearby landmarks, like the Statue of Liberty and the Empire State Building. They discuss what they should do first; Shaggy and Scooby want to taste local cusine, but the others want to explore the city.
They end up wallking down Central Park when a flustered woman rushes by carrying some flowers in a pot. She knocks into the gang and drops her flowers. Daphne instantly recognises the woman and says "LeShawna?", the woman looks up and replies, "Daphne?", with a smile on their faces. They hug and introduce eachother. It is revealed that they went to fashion college together. LeShawna then invites them back to her flower shop.
They are next seen inside the flower shop where LeShawna mentions the recent going-ons in the shop and explains that a monster has been terrorizing her shop. She refers to it as the 'Bouquet Beast' and says that it has been wrecking her shop regularly. At this moment, a man enters asking for some flowers. LeShawna knows the man and introduces him to the gang. The man (Felice) says that he lives on the same street as the shop with his mum, Rose, who he is buying flowers for. Fred asks him if he's seen anything of the monster seeing as he lives nearby, but he says he doesn't know about any monster.
Cast and CharactersEdit
|Frank Welker
|Scooby-Doo & Fred Jones
|Matthew Lillard
|Shaggy Rogers
|Mindy Cohn
|Velma Dinkley
|Grey DeLisle
|Daphne Blake
|Kimberly Brooks
|Rino Romano
|Jeff Bennet
- Buds & Blossom Florists, New York City
|Previous Episode:
Erupt & Corrupt
|Next Episode:
Belle of the Ball


text:
I am a theatre historian who has written two books about Australian Theatre History whilst recovering from Graves Disease. I run a website, HAT-History of Australian Theatre, write for Stage Whispers Magazine and for suite101.com.
I'm also a teacher of English as a second language, a juggler and a student of Mandarin
I live in Sydney Australia surrounded by books, lovebirds and light.


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KEY Pink font: no objectives specifiedwhite: not in the midtermOrange: included in the OSCEBlue: assignment required(-/): lecture available in dropbox (riyadh or jeddah)(IC): incomplete
General anatomical terms, planes, movements and structures. The basic language used to identify structures (or parts thereof), their functions and their relationships with other structures in the body.
General anatomical organization of skin, bones, joints and skeletal muscles
General anatomical structure and organization of arteries, veins and lymphatics
General anatomical structure and organization of smooth muscle, cardiac muscle and viscera. Aim An introduction to smooth muscle, cardiac muscle and viscera. Content • The general differences in structure, function and location of cardiac and smooth muscle • Viscera (hollow/solid, sphincters/obstruction of hollow viscera, endocrine & exocrine glands) General location of viscera within different body systems (respiratory, cardiovascular, gastrointestinal, genitourinary) Structure and function of serous membranes (pleura, pericardium, peritoneum) The nerve supply to viscera (sympathetic, parasympathetic, visceral afferents)
General anatomical structure and organization of the trunk - the structures and make-up of the thorax and abdomen.
General anatomical structure and organization of the head and neck - the general framework of the bones, muscles, organs, blood and nerve supply.
General anatomical structure and organization of the central nervous system; from spinal cord to cortex. Key features of neural cells and what makes them special.
General anatomical organisation of the peripheral nervous system; the nerves and plexuses. Key features of peripheral cells and the formation of plexuses. The main dermatomes and myotomes, how they develop and why they are important. The concept of referred pain
Objective: General anatomical organization of the limbs, the framework of bones, joints, ligaments, muscles, arteries and nerves. The organization of block 1
Objective: Detailed anatomical organization of the bones and joints of the upper limb. The movements at each joint - shoulder, elbow, wrist and those in hand. Aim An overview of the bones and joints of the upper limb. Content • The bones of the upper limb including their structure, relationships and function. • The joints of the upper limb including their structure, relationships and function.
Objective: Detailed anatomical organization of the muscles of the shoulder and arm; their attachments and functions. The functions for each individual muscle and its action on the major joints, namely shoulder, elbow, acromioclavicular and sternoclavicular. Aim An overview of the muscles of the forearm. Content • • • • The muscles of the forearm region including their structure, relationships and function. The muscles of the hand region including their structure, relationships and function. The connective tissues of the hand. The topographical relationships of the forearm and hand
Objective: Detailed anatomical organization of the muscles of the forearm and hand; their attachments and functions. The action of each muscle on the major joints, for example, elbow, wrist, and those in the hand. Aim • An introduction to the organisation of the muscles of the upper limb, shoulder and arm Content • Students should be able to describe the general attachments and actions of the following muscle groups: • Rotator Cuffs: supraspinatus, infraspinatus, teres minor, subscapularis • Shoulder: pectoralis major et minor, trapezius, latissimus dorsi, levator scapulae, rhomboids, teres major, deltoid • Arm; biceps, triceps, coracobrachialis, brachialis
Objective: Detailed anatomical organisation of the blood vessels of the upper limb, their major course and innervations.
Objective: Aim • To present an overview of the nerves of the upper limb. Content • • • • The structure and relationships of the plexuses of the upper limb. The course, relationships and structures supplied for the major nerves of the upper limb. A general description of a peripheral nerve lesion. Examples of upper limb peripheral nerve lesions.
General histological organization of cells and tissues found in the body
General histological organization of cells and tissues found in the body
General histological organization and different types of connective tissue and muscle.
General histological organization of lymph,blood vessels and nerve tissue in body.
General histological organization of Gastrointestinal Tract in body
Key concepts of homeostasis and their application to the regulation of body temperature and plasma osmolarity
Mechanisms that regulate and maintain intracellular homeostasis.
Mechanisms for intracellular communication, using illustrative examples.
Key mechanisms for intercellular communication, using illustrative examples Aim To explain key mechanisms for intercellular communication and examine illustrative examples. Content • • • • • • • Distinguish between electrical and chemical signalling and identify an example of each Distinguish between endocrine, paracrine and autocrine signalling and identify an example of each Describe the ionic signalling processes that occur at the neuromuscular junction and apply them to the mechanisms by which botulinum toxin, myasthenia gravis and organophosphates affect neuromuscular transmission Describe the molecular basis of electrical excitability Describe the molecular basis of nerve conduction and apply it to the mechanisms by which tetrodotoxin affects nerve conduction. Appreciate the effects of myelination and of fibre diameter on conduction rate Appreciate the features of hormonal signalling as illustrated by the regulation of plasma glucose levels by insulin
Objective: Principle maternal physiological adaptations to pregnancy
Objective: Processes involved in cell division and growth, with reference to key mechanisms for normal and disordered events in the cell cycle. Aim To explain the processes of cell division and growth, with reference to key mechanisms for normal and disordered events in the cell cycle. Content • • • • • • major events of the cell mammalian cell cycle roles of cyclins and cyclin-dependent kinases in driving the cell cycle restriction point, the G1/S and the G2/M check points role of growth factors and other environmental factors in regulating entry to and exit from cell proliferation importance of disordered signalling in driving cancer cell cycles (c-abl and CML, oestrogens, Epidermal Growth Factor and breast cancer) role of apoptosis as a mechanism for correcting errors and regulating cell numbers
Basic concepts of the cell cycle and nuclear events, mitosis and meiosis. The methods for visualisation of chromosomes in cell division, together with the advanced methods for high resolution in premetaphase (using example of Prader-Willi syndrome). Aim Cell cycle and nuclear events Methods for visualization of chromosomes in cell division Mitosis, DNA replication, anaphase, prophase metaphase, interphase Meiosis I & II – timing in - reproductive cycle in males and females - Crossing over/recombination • Advanced methods for high resolution in premetaphase - Karyotyping - FISH - Chromosome Painting - Comparative Genomic Hybridisation - Array CGH • Basic example - Prader-Willi syndrome - FISH - Deletion/duplication by array CGH
Overall genetic paradigm DNA, RNA, Protein, the chemical nature of DNA, the organisation of the double helix, the mechanisms of transcription and translation, the significance of the genetic code, the different types of mutations, and finally, the concept of protein misfolding. Aim Genetic Paradigm DNA→RNA→Protein Chemical Nature of DNA Double Helix Genes and Chromosomes Transcription Translation Genetic Code Types of mutations/silent, nonsense, missense Protein misfolding
Objective: Aim Epidemiology of Genetic Disorders Levels of Treatment - The Family - Clinical Phenotype - Biochemical Disorders - Mutant Protein - Mutant Gene • Triplet mutations • Ethical dilemmas in Treatment of Genetic Disorders • Basic Prenatal Genetic Diagnostic Strategies (2-3 slides)
Principles of pathogenesis of dental caries and periodontitis. The main clinical manifestations of dental infection in terms of underlying pathophysiological processes. Aim • • • Principles of the pathogenesis of dental caries and periodontitis will be outlined, as will the main clinical manifestations of dental infection in terms of underlying patho- physiological processes. In particular, the nature of dental plaque and its role in caries development, as well as the progressive spread of infection from the surface of the tooth to the pulp, periapical tissues and then soft tissues. The systemic effects of this will be outlined, while the development of chronic periodontitis will also be discussed. Attention will be drawn to the basic principles of inflammation using dental infection as an example.
Major oral diseases and their distribution in the Saudi population. The disparities in oral disease burden between different demographic groups and the current evidence linking oral and systemic disease. The major challenges facing the prevention and management of oral disease in Saudi Arabia. Aim • • • • • • The major oral diseases and their distribution in the Saudi population. The disparities in oral disease burden between different demographicgroups. The current evidence linking oral and systemic disease. Examples will include cardiovascular disease, obesity, preterm birth and certain cancers. The oral disease burden in the medically compromised. The major challenges facing the prevention and management of oral disease in Saudi Arabia. The main approaches for prevention, including fluoridation, personal oral hygiene, fissure sealants and surgical intervention. Emphasis will be on the need for an informed preventive strategy tailored to the needs of the patient.
Objective: Defining the meaning of psychiatry, cinematic interlude and psychotic and anxiety disorders.
Objective: Widespread nature of mental illness in the community, the range of psychotic illness in the community and some basic symptoms of psychosis. The plasticity of the brain and changes in both function and structure that mental effort causes.
Objective: Major stages of early development of the human embryo
Objective: Major defects associated with the developing embryo during pregnancy
Objective: Aim Rather than addressing the age-old dichotomy between "biologically normal ageing" on the one hand and "disease" on the other. The aim of this lecture is to define a relatively new and highly practical approach to human ageing; ie the distinction between successful and unsuccessful ageing and how to bring this about. Content Students should be able to: • • • • • • • • Define successful ageing and understand the current models and approaches. Describe how we measure successful ageing. Understand the difference between maximum lifespan and life expectancy, and how these have changed (or not) over the years, and be aware of the Saudi demography. Describe biological and cellular theories of ageing. Describe genetic and environmental protective factors for successful ageing and also the risk factors for unsuccessful ageing, their interactions and effects. Understand the aims of health promotion and public health intervention. Understand the concept of "compression of morbidity", and whether this has been proven around the world and in Saudi Arabia. Understand why are older people "at risk" in our hospitals and health care system. Understand the concepts of threshold, failure of homeostasis and the resulting syndromes of Geriatric Medicine, also called the "Giants of Geriatric Medicine".
Basic principles underlying the processes of cellular injury, adaptation (atrophy, hypertrophy, hyperplasia, dysplasia, metaplasia), ageing, and the two chief mechanisms leading to cell death (necrosis and apoptosis).
Major processes of tissue renewal and repair in the body. Aim An introduction into the processes of tissue renewal and repair Content • • • • • the control mechanisms that exist in normal cellular proliferation and tissue growth the basic cell cycle and the concept of the stem cells soluble factors and signalling mechanisms for growth the role and significance of the extracellular matrix and the overall process of angiogenesis fundamental concepts of regeneration, healing, scar formation/fibrosis
Significance and the process of Anatomical Pathology and Laboratory Diagnostics. Aim • The students to understand the role of Pathology in the diagnosis and management of disease. Content anatomical pathology chemical pathology hematology microbiology/immunology genetics
Objective: Role of acute inflammation in normality anddisease, the cellular and soluble componentsassociated with and that produce inflammationand finally, the outcomes and controlmechanisms of inflammation.
Objective: Meaning of neoplasia and nomenclature of tumours, the similarities and differences between benign and malignant tumours, the mechanism of underlying neoplastic transformation and accumulation of genetic damage, the basic morphology of tumours, both in macroscopic and microscopic terms, the mechanism underlying metastasis and finally, the overall risk factors for cancer. Aim • An introduction into the concept of neoplasia Content • • • • • • meaning of neoplasia and nomenclature of tumours similarities and differences between benign and malignant tumours mechanism of underlying neoplastic transformation and accumulation of genetic damage basic morphology of tumours, both in macroscopic and microscopic terms mechanism underlying metastasis the overall risk factors for cancer
Objective: Role of chronic inflammation in normality and disease, the cellular and soluble components associated with and that produce inflammation and finally, the outcomes and control mechanisms of inflammation.
Relationship between the science of pharmacology, the discipline of clinical pharmacology and the scientific basis of rational prescribing of medications.
Diversity of mechanisms by which drugs can have beneficial effects in treating human disorders.
Concepts of dose-response, antagonism and the associated metrics such as EC50 and ED.
Mechanisms by which the body absorbs and metabolises drugs and the potential for disease states (or other drugs) to compromise the body's drug metabolising capacity. Aim • To examine the mechanisms by which the body absorbs & metabolises drugs and the potential for disease states (or other drugs) to compromise the body's drug metabolising capacity. Content Students should be able to explain the role and effects of the following on drug metabolism: the mechanism of liver metabolism of drugs cytochrome (CYP) P450 genetic polymorphism of CYPs drug metabolism as a basis for drug interactions routes of drug administration and absorption
Objective: Assessment of drug effects in patients. The circumstances where measurement of drug concentrations in the blood may assist in optimizing drug dosing.
Objective: Issues underlying adverse events (AEs) associated with drug administration and the clinical management of drug overdose.
Objective: Aim To describe the use and abuse of legal and illicit drugs for non-medical purposes. To explain what is known about the associated dependency and psycho-active properties of these drugs. Content Students should be able to outline the non –medical use of the following substances, including their psycho-active properties: alcohol nicotine opiates amphetamines & related substances cannabis
Major nutrients and nutrient-sensing systems; significance of lipids, carbohydrates, oligo- and disaccharides, monosaccharides and proteins and amino acids and the control of digestion, absorption, appetite and satiety (together with the hormonal control of nutrient disposal and storage).
Metabolic pathways converting nutrients to energy, for example, the anaerobic and aerobic metabolism of glucose, fatty acid oxidation and the concept and function of ATP.
Mechanisms by which oxygen makes energy from nutrients.
The evidence that DNA is the "genetic material" and that bacteriophage DNA changes the morphology/phenotype of bacterial cells. The purines and pyrimidines, nucleosides and nucleotides, the constraints used to model the structure of DNA, the identity of genes and the genetic code. Aim Evidence that DNA is the "genetic material" Bacteriophage DNA changes the morphology/phenotype of bacterial cells Early ideas on the nature of genes and gene copying: a "complementary surface" Chemical analysis demonstrates that DNA is made from building blocks that include: two types of organic base* (purines and pyrimidines) as well as 2-deoxyribose and inorganic phosphate The two Purines of DNA: Adenine; Guanine The two Pyrimidines of DNA: Cytosine and Thymine Nucleosides and Nucleotides Constraints used to model the structure of DNA: A sugar-phosphate backbone Helical pattern on XRay diffraction of DNA fibres Chargaff's rule: No matter what the source of DNA: Adenine and Thymine levels are equal; Guanine and Cytosine levels are equal Key assumptions necessary the Watson-Crick solution: • • • • • • • two rather than one or three helices external location of the sugar-phosphate backbone base-pairing by hydrogen bonds according to Chargaff's rules i.e., G:C; and A:T DNA synthesis from deoxyribo-nucleoside triphosphates (dNTPs) Identity of genes Discovery of the complementary surface for gene copying The genetic code: its triplet nature and detailed description * molecule that accepts protons
Objective: A comparison of the structures of DNA and RNA, the different species of RNA and their roles, the roles of messenger RNA, ribosomal RNA, transfer RNA and microRNA, the role of the nucleolus in the genesis of ribosomes, modifications to messenger RNA in eukaryotes that enhance its stability and its ability to dock with ribosomes for translation, the origin of complex structures in RNA, the composition of ribosomes, the structural organization of amino acid-loaded transfer RNAs, base-pairing between codons in mRNA and anticodons in tRNA, significance of and differences between DNA and RNA viruses as well as RNA(+) and RNA(-) viruses, retroviruses and how they interact with the host genome, reverse transcription, reverse transcription PCR, and finally, ribozymes: definition and examples
No specific objectives in block book
Objective: How enzymes facilitate chemical reactions, influence reaction rates and the meaning of the Michaelis-Menten analysis. The three modes of inhibition and that enzymes are important drug targets in medicine and also toxin targets. Enzymes are both extracellular and intracellular, they are regulated in many different ways and that allosteric modulation of enzymes controls activity of metabolic pathways.
Objective: Major nutrient stores and tissues and what occurs during feast and famine. The general function of the liver, adrenal gland and pancreas. The significance of the key hormonal controllers.
Objective: Aim To present a rationale for the use of biochemical tests esp. troponin in the diagnosis of acute myocardial infarction. Content Definitions and basic concepts How AMI can be diagnosed from biochemical tests Troponin as a biomarker for AMI (and some `traps for new players') Summary References & further reading
Function and organization of the innate and adaptive immunity, their different components and cell types. The significance of primary and secondary lymphoid tissue and their role in stimulating adaptive immunity
Function of different types of immune cells, T cells and dendritic cells. The meaning of MHC complex and how it functions to regulate immune response. The mechanisms of how protein antigens are processed and the endogenous and exogenous antigen pathways.
B and T cell receptor structure (+signaling molecules associated with these receptors), the different classes of antibodies, the development of receptor repertoires (using Ig genes as example) and the clonal selection theory. Aim B cell receptor (BcR) structure; surface-bound Ig Classes of antibodies T cell Receptor (TcR) structure and development Signalling molecules associated with TcR and BcR Development of receptor repertoires using Ig genes as example Clonal selection theory
Mechanisms of antigen recognition of the MHC peptide complex by T cells, the co-stimulation for maximum activation of T cells, the T cell response to activation, the differentiation to effector and memory T cells, and the expression of cytokines and cytokine receptors. The changes in lymphocyte migration to sites of infection and inflammation.
Objective: Mechanisms of antigen recognition of the MHC peptide complex by T cells, the co-stimulation for maximum activation of T cells, the T cell response to activation, the differentiation to effector and memory T cells, and the expression of cytokines and cytokine receptors. The changes in lymphocyte migration to sites of infection and inflammation. Aim The student can explain the T cell related mechanisms of: • Antigen recognition of the MHC-peptide complex by T cells Co-stimulation for maximum activation of T cells (signal 1 and signal 2) • • • T lymphocyte responses to activation: clonal expansion and cytokine production (role of IL-2 and IL-2R in T cell proliferation) Differentiation to effector (Th1 and Th2 subsets), and memory T cells, and expression of cytokines and cytokine receptors Changes in lymphocyte migration to sites of infection & inflammation
Objective: Mechanisms of: Central T and B cell tolerance, peripheral T and B cell tolerance, genetic factors in autoimmunity, the role of infections in autoimmunity, and finally, some selected autoimmune disease.
Objective: The student understands the principles of: • Transplantation to 'correct' deficit or disease: - Examples of organ and tissue grafts - Major and minor histocompatibility - Immune response to transplants - Circumventing immune responses by tissue matching and immunosuppression - Bone marrow transplants and gene therapy
Significance of microbial diversity, prokaryotic,eukaryotic and sub-cellular microbes. What distinguishes commensal microbes from pathogens, together with the epidemic control and disease eradication. The concept of antimicrobial chemotherapy and understand that there is a continual emergence of "new" infectious diseases.
No objectives specified Dr. Al AmriMonday, 10 september, 9-10 am
Objective: Organisation and function of RNA viruses, DNA viruses and Prions. Aim RNA viruses – structure, composition, genetics, replication DNA viruses – structure, composition, genetics, replication Prions
Objective: Factors promoting colonisation, adherence, motility and Fe acquisition. The mechanisms involved in evading host defences; capsules,inhibition of phagocytosis, protein A. The factors that damage the host; exotoxins, endotoxin, hydrolytic enzymes. Aim • Factors promoting colonisation - adherence, motility, Fe acquisition etc • Evading host defences - capsules, inhibition of phagocytosis, protein A etc Factors that damage the host Exotoxins, endotoxin, hydrolytic enzymes etc
Objective: Means by which viruses spread through the host, the genetic determinants of viral virulence, and the mechanisms of disease production. The mechanisms of viral damage to tissues and organs, virus-induced immunopathology, persistent and latent infections and viral oncogenesis.
Objective: Bacterial culture methods, virus isolation by cell culture, rapid antigenic detection methods, molecular diagnosis and finally, serology.
Objective: Antimicrobial therapy and the emergence of resistance, sterilization and disinfection, immunization, surveillance and vector control, public health engineering and finally, prevention of zoonotic infections and overall food safety.
Objective: Measures taken to prevent infection, including: quarantine, hygiene and sanitation, vector control and prevention of exposure to vectors, immunization and the eradication of infectious diseases.
Objective: Major issues related to women's health: puberty, menstruation, contraception, fertility and infertility, pregnancy, childbirth, postpartum, menopause and old age.
By the end of this teaching activity, students should be able to: • list the major factors that affect the distribution of ill health (burden of disease) in Saudi and International populations. • Compare in broad terms different methods of measuring disease burden.
Objective: By the end of this teaching session, students should be able to: • • • • • define a communicable disease explain what is required for the development, implementation and evaluation of health policies describe the legislative underpinnings of public health policy describe the priorities and strategies for public health policy in Saudi Arabia understand the principles of disease surveillance and the investigation of a disease outbreak
Objective: Aim To introduce and describe the rationale, purposes and data sources for disease surveillance and apply them to the investigation of outbreaks Content Students should be able to: • • • • define surveillance explain the importance of public health surveillance describe how surveillance is carried out in Saudi Arabia understand the principles of disease surveillance and the investigation of a disease outbreak


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Download the Game Design and Indie Game Marketing Freebook 07/19/17GameDev.net and CRC Press have teamed up to bring a free ebook of content curated from top titles published by CRC Press. The freebook, Practices of Game Design & Indie Game Marketing, includes chapters from The Art of Game Design: A Book of Lenses, A Practical Guide to Indie Game Marketing, and An Architectural Approach to Level Design. The GameDev.net FreeBook is relevant to game designers, developers, and those interested in learning more about the challenges in game development. We know game development can be a tough discipline and business, so we picked several chapters from CRC Press titles that we thought would be of interest to you, the GameDev.net audience, in your journey to design, develop, and market your next game. The free ebook is available through CRC Press by clicking here. The Curated Books The Art of Game Design: A Book of Lenses, Second Edition, by Jesse Schell Presents 100+ sets of questions, or different lenses, for viewing a game's design, encompassing diverse fields such as psychology, architecture, music, film, software engineering, theme park design, mathematics, anthropology, and more. Written by one of the world's top game designers, this book describes the deepest and most fundamental principles of game design, demonstrating how tactics used in board, card, and athletic games also work in video games. It provides practical instruction on creating world-class games that will be played again and again. View it here. A Practical Guide to Indie Game Marketing, by Joel Dreskin Marketing is an essential but too frequently overlooked or minimized component of the release plan for indie games. A Practical Guide to Indie Game Marketing provides you with the tools needed to build visibility and sell your indie games. With special focus on those developers with small budgets and limited staff and resources, this book is packed with tangible recommendations and techniques that you can put to use immediately. As a seasoned professional of the indie game arena, author Joel Dreskin gives you insight into practical, real-world experiences of marketing numerous successful games and also provides stories of the failures. View it here. An Architectural Approach to Level Design This is one of the first books to integrate architectural and spatial design theory with the field of level design. The book presents architectural techniques and theories for level designers to use in their own work. It connects architecture and level design in different ways that address the practical elements of how designers construct space and the experiential elements of how and why humans interact with this space. Throughout the text, readers learn skills for spatial layout, evoking emotion through gamespaces, and creating better levels through architectural theory. View it here. Learn more and download the ebook by clicking here. Did you know? GameDev.net and CRC Press also recently teamed up to bring GDNet+ Members up to a 20% discount on all CRC Press books. Learn more about this and other benefits here.
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About BuraCULa
BuraCULa posted a topic in Graphics and GPU ProgrammingHello. I work on a renderer framework. When I create texture with CreateTexture2D, D3D11 device immediatly allocates some memory from virtual space of the process despite there is no cpu access flags etc. or staging usage specified. I've read Windows manage paging of gpu resources so that memory of gpu resources are moved to system memory to create empty space for recently used resources. My process consumes 2 gb of memory for render targets and total gpu memory usage is about 3 gb. Gpu has 8 gb physical memory but 1 gb of system memory(Committed virtual memory) of process is still used by D3D11 resources. I checked this with PerfView tool which tracks all virtual memory allocations. I checked committed address spaces of other D3D11 games but it seems their gpu resources does not consume any system memory. There isn't much information about this behaviour on internet. I would greatly appreciate if anyone enlighten me. Thanks.
BuraCULa posted a topic in Graphics and GPU ProgrammingHello. I am trying to make my flat terrain a little bumpy and I saw Outerra's old implementation. It looks pretty well but I couldn't figure it out. It seem POM is used but I tried lots of combinations with POM and normal mapping and I couldn't achieve that sight. Do you have any idea about how to achieve such a perfect bumps on grass.
BuraCULa replied to BuraCULa's topic in Graphics and GPU ProgrammingHmm. So it seems i need to change my format to L8 and it is gonna be loaded as R8. Thank you. [img]http://public.gamedev.net//public/style_emoticons/default/smile.png[/img]
BuraCULa posted a topic in Graphics and GPU ProgrammingHi. I have a texture with format A8_UNORM. When i try to sample it in pixel shader it was returning just zero.But when i changed my shader variable from [CODE]Texture2D<float> sth[/CODE] to [CODE]Texture2D<float4> sth[/CODE] and in shader, sampled the alpha component instead of the red component (sth.Sample(...).a instead of sth.Sample(...).r) it worked well.I am really confused with this situation. Although my texture has single channel,i am able to sample it with Texture2d<float4>.Can someone please enlighten me?
BuraCULa posted a topic in Graphics and GPU ProgrammingHi. I am trying to pack my view space normals into two float with spheremap transformation. Actually i can pack and unpack them well but, while packing specific vectors - (0,0,1) and (0,0,-1) - , the algorithm is trying to call normalize(0,0). So this is causing a infinite result. Is there any way to solve this without placing some if statements into packing and unpacking functions ? I am using functions from [url="http://aras-p.info/texts/CompactNormalStorage.html"]here[/url].
BuraCULa replied to BuraCULa's topic in Graphics and GPU ProgrammingYes i didn't know i have to unset it before bounding it to CS.Now it is working well.Thank you MJP [img]http://public.gamedev.net//public/style_emoticons/default/smile.png[/img]
BuraCULa posted a topic in Graphics and GPU ProgrammingHi. I am trying to implement deferred shading technique.I am encoding my normals into a render target in pixel shader.Then i am bounding shader resource view of this resource to the compute shader.In PIX, i can see that the surface is bounded to CS so everything works fine but when i try to sample any normal data it just returns "0". Here is my simple code but it doesn't work.As you can guess it is just filling surface with blue. [code]#define TILE_SIZE 16 RWTexture2D<float4> gOutTexture : register(u0); Texture2D<float2> gInputTexture : register(t0); /*--------------------- COMPUTE SHADER FUNC ----------------------*/ [numthreads(TILE_SIZE,TILE_SIZE,1)] void DeferredShadingCS(uint3 groupId : SV_GroupID, uint3 dispatchThreadId : SV_DispatchThreadID, uint3 groupThreadId : SV_GroupThreadID ) { float2 data = gInputTexture.Load(uint3(dispatchThreadId.xy,0)); gOutTexture[dispatchThreadId.xy] = float4(data,1,1); } [/code]
BuraCULa replied to BuraCULa's topic in Graphics and GPU ProgrammingI am trying to create a output texture for compute shader and copy this texture to render target after CS finished working.Actually I am just trying to start working on deferred shading. Does that conversion cause a performance penalty ? Because my hw doesn't support 128 bit textures for render targets and so i can't create swap chain with R32G32B32A32 etc. --Edit-- After some researches i got some informations like half is not so important and 32 bits surfaces are pretty enough for deferred shading techniques.So i should look for some packing algorithms like this [url="http://aras-p.info/texts/CompactNormalStorage.html"]http://aras-p.info/texts/CompactNormalStorage.html[/url]. Thanks for your reply MJP.
BuraCULa posted a topic in Graphics and GPU ProgrammingHi.I can't compile following code.Compiler says "typed UAV stores must write all declared components.".But when I use float4 instead of half4 it works well. What does that error mean? [img]http://public.gamedev.net//public/style_emoticons/default/unsure.png[/img] [code] RWTexture2D<half4> gTexture : register(u0); [numthreads(TILE_SIZE,TILE_SIZE,1)] void CS(uint3 groupId : SV_GroupID, uint3 dispatchThreadId : SV_DispatchThreadID, uint3 groupThreadId : SV_GroupThreadID ) { gTexture[dispatchThreadId.xy] = half4(1,1,1,1); } [/code]
BuraCULa posted a topic in Graphics and GPU Programminghi. I am trying to implement fft algorithm on gpu via compute shader. Actually i am trying to convert my working c++ code to hlsl code. Since i couldn't do it, i tried to make code as simple as i can,and deleted and updated some parts of the shader function.But still i cant read from the buffers correctly. It reads zeros from the buffers although the buffers were initialized correctly(wValues and rIndices buffers have correct values). I am usin pix to view the buffers. I am new to hlsl and i guess i am making very stupid mistake somewhere.Where is my mistake :/ [code]struct Complex{ float re; float im; }; // group sizes #define FFT_DIM 16 #define log_2_n 4 cbuffer Algo{ int FFT_DIR; float time; }; Buffer<uint> rIndices:register(t0); Buffer<float> wValues:register(t1); RWStructuredBuffer<Complex> hTValues:register(u0); [numthreads(FFT_DIM,1, 1 )] void FFTShader( uint3 threadIDInGroup : SV_GroupThreadID){ float2 c[FFT_DIM]; int w_c=0; int w_cc=1; int loops = FFT_DIM>>1; int size = 1<<1; int size_over_2 = 1; int toffset=0; if(FFT_DIR==0){ for(int i=0 ; i<FFT_DIM ; i++){ c[i] = wValues[i]; } } if(FFT_DIR==0){ for (int i = 0; i < FFT_DIM; i++){ hTValues[i + FFT_DIM*threadIDInGroup.x].re = c[i].x; hTValues[i + FFT_DIM*threadIDInGroup.x].im = c[i].y; } } }[/code]
BuraCULa replied to BuraCULa's topic in General and Gameplay Programmingi am not spending my time to solve their problem.I try to find the mistake because i am sure one day, also i will face with that problm for my own work.
BuraCULa replied to BuraCULa's topic in General and Gameplay Programmingtypedef struct DUGUM { int Case[3][3]; float estimated; float current; struct DUGUM * children; int childrenCount; struct DUGUM * parent; }DUGUM,*PDUGUM; this is the DUGUM struct.I am trying to use a* algorithm to solve 8 puzzle problem.Infact my c++ code works fine with directx and can find the solution but i writed this code for my friends,they dont know classes and c++.This is a homework :) case[][] member of struct stores the current positions of the tiles.In memcmp call it looks if the current positons of tiles are same with the goal node. 1 2 3 0 5 6 4 7 8(current) 1 2 3 8 0 4 7 6 5(goal)
BuraCULa posted a topic in General and Gameplay ProgrammingHi I have been trying to find the mistake about 1 day.I use <list> library.When i add somedata to list, it works fine couple of times but then it gives me an error: "windows has triggered a breakpoint. This may be due to a corruption of the heap bla bla" and shows me function __forceinline void * __cdecl _heap_alloc (size_t size). DUGUM* Solve(DUGUM *start){ std::list<PDUGUM> queue; std::list<PDUGUM> queue2; queue.push_front(start); DUGUM* temp = NULL; while(! queue.empty()){ temp = queue.back(); queue.pop_back(); if( memcmp(&temp->Case[0][0],&GOAL[0][0],sizeof(int)*9)==0 )break; queue2.push_back(temp); FindChildren(temp); for(int i=0 ; i<temp->childrenCount ;i++){ queue.push_front(&temp->children[i]); //error line } } } and before the while loop i can add data to list with no error.I belive this line is curved :)
BuraCULa posted a topic in Graphics and GPU ProgrammingHi.Im very confused.What is the difference between hDeviceWindow and hFocusWindow.I created a full secreen device,and hDeviceWindow is NULL, but it still collects message like mouse clicks.What job does devicewindow have?
BuraCULa replied to BuraCULa's topic in Graphics and GPU ProgrammingThank you both.My zbuffer value in clear call was 10.0F, i changed it to 1.0f.Now there is no error.


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