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5.0 stars 3 totalReview Philip Barnett
Posted by Sahil
Philip has all the qualities you would look for before hiring an Attorney. I have consulted other lawyers but Philip was the best one I ever came across.
Knowledge - 5 stars
Fee - 5 stars (very reasonable - won't rip you off like other lawyers)
Communication - 5 stars (Would listen and communicate in simple language so normal people can understand)
Getting a hold - 5 stars (He gave me his cell phone no and would always answer my call, You wouldn't want to hire a lawyer whom it would take a whole business day to reach)
Hope I would never have to hire a lawyer again but if I did, I would definitely go for Philip Barnett.
Posted by J.J.
Phil has represented me three times for DUI cases. In each instance, Mr. Phil was direct and honest with me about the possible resolution to each case. At no time did he make any false promises; rather, he did an outstanding job setting realistic expectations for me regarding what the court might decide in each instance. Along with being upfront, honest, and understanding during those stressful times, Mr. Phil skillfully directed my cases within the court system, using his knowledge and experience, to get my case heard based on our discussed and agreed upon timeline and preferred approach. I am very thankful for the way Mr. Phil dealt with me - he returns calls very quickly, usually that same day, if not within a few hours. He was always on time, if not early, to court. It was very clear to me that the court respects him, which allowed him to obtain for me resolutions to my cases that were more than I thought possible. Because of his diligence and approach, I have referred Mr. Phil to friends, and he has obtained similar results for them. I would recommend Mr. Phil to anyone that wants a professional lawyer of the highest standard to handle their case.
Posted by Emily
Phil Barnett is an excellent attorney. I hired him as my criminal defense attorney because he was honest with me, straightforward, professional, and always treated me with respect. Barnett explained every aspect of the legal processes related to my case. He succeeded in getting the best possible outcome for me during sentencing. His expertise was very comforting to myself and my family during a very difficult time.


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Parkway Village Apartments in Escondido, CA
Located at 1825 East Valley Parkway, Escondido, CA 92027
1825 East Valley Parkway, Escondido, CA 92027
Disability access, Laundry facility, Dishwasher, Disposal, Patio/balcony, Covered parking
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The People We Serve
The Story of Nang Pe: Midwife Saves Lives in Ga Naing Nge West Village
My name is Nang Pe and I live in Ga Naing Nge West village. I have three children and my husband is Khun Lan. We grow cheroot leaves that are used to make cigars. When I was pregnant with my last child, I took prenatal vitamins from our Village Nurse Midwife (VNM), Phyu Thazin Oo, but I didn't plan to deliver my baby with her because I had successfully delivered my first two children with the Traditional Birth Attendant (TBA, an untrained woman who assists at births) from the village.
But the last birth, when I used the TBA, was really difficult for me. Three hours after the birth, the placenta had not come out and my abdomen was very painful. My baby was very cold and the TBA didn't cut the umbilical cord. I was very afraid and I thought my baby and I would die. The TBA told me to wait and it would all be ok. Finally, we called for Nang Phyu Thazin Oo who would understand my condition.
When the VNM arrived, she asked about my symptoms and she cut the baby's umbilical cord. She told me to go to the hospital immediately and that we should not waste any more time. It is not easy to get to the hospital in Taunggyi and took about one hour by motor bike and the VNM went with me. The doctors at the hospital invited her to the delivery room to assist in removing the placenta. All the doctors from the hospital told me she saved my life.
If Nang Phyu Thazin Oo was not there, I am sure I would have died. Now, I understand very well about health care. I will teach the other women in our village how important it is to use our VNM. We are really lucky to have a clever and patient nurse midwife for our village. Nang Phyu Thazin Oo works unselfishly and patiently for our village and is trusted by the villagers. Now, it is ok to talk about disease, health care and medicine. If I am ever ill, I will go to her for care. And, after our VNM gives vitamins to the under 5 year's old children, the children are healthier and stronger than before.
I am very thankful to Shanta Foundation who is helping our village in many ways.
Success Story of Village Nurse Midwife from Lone Chin
The duties of a village nurse midwife include home birth deliveries, providing contraception for the women, prenatal care, treatment of minor illness, referring serious illness cases to the hospital and monthly weighing and giving vitamin for village children under 5 years old. This is the success story of 23 year old Nang Htun of Lone Chin village. She and her carpenter husband Khun Kyaw Moe have one son. Before attending the 6 month training to become a midwife from August 2011 to February 2011 she was a farmer in the fields. Lone Chin did not have a nurse midwife prior to Nang Htun. The following interview show what in impact this training has on the entire village.
How has having a village nurse midwife impacted the village?
If people sick, they had to go for a 20 minute walk to get treatment. And also if the pregnant woman can't deliver at home with the traditional birth attendant, her family had to go far away to take her to a midwife. This situation put some pregnant women were in danger. Since the clinic is so far away, most of villagers don't care their minor illnesses and some cause more serious like diarrhea, hypertension, wounds and skin infection.
Now I can support and I can care for our villager's health. Most of the villagers came and take medicine, get contraception and get health education how to take care themselves at home when they are sick. Now not as many people get the Flu during seasonal changes.What feedback have you received from the villagers about this Village Nurse Midwife training?
All of the villagers are happy and thankful to Shanta for this program. As a village and we can't afford to attend this kind of training. They are happy because they don't need to go anywhere to get medicine and to give birth. Another benefit is cost for medicines and delivery are less expensive than travelling to another place because I charge a little amount of money. Not only did Shanta support me when I was at training but also the villagers supported my family with foods while I was gone.
Tell me about your personal changes and successes since becoming a nurse midwife?
It has really helped my family now that I have a job that I can make money from and no longer need to work hard in the field. I'm very pleased and proud of myself to work as a nurse midwife and take care of our villager's health. I have delivered 3 babies from our villages. Some of the pregnant women didn't deliver with me but I did regular prenatal care for them. I understand about the medicine, how to use safely and how to inject.
Are there any difficulties or challenges you've face while working as a village nurse midwife?
Yes, I have. One time when I delivered a baby, the baby was come out with breech not with head. So I went to nearest sub centre and called the midwife to deliver that baby with breech. The baby was delivered successfully and I learned how to deliver with breech presentation from that midwife.
The second one was one villager came to me with deep yellow skin and I knew that it was serious case. So I took him to a tertiary center (Taunggyi Hospital) to get proper treatment. Doctors from the hospital said we arrived just in time and I saved his life. Now that villager can work again in his field.
What are other projects or programs of Shanta do you and your family participate?
My family participates in pig farm project, loan fund, coffee, and solar projects. We now have three pigs, about 100 coffee plants, and solar lights in our home. We already sold four piglets and have put the money into savings! I think every project working together with Shanta is successful. I am also a teacher at the village daycare center.
Do you want to say anything or any suggestions?
I thank Shanta Foundation, without them I would have never even dreamed of becoming a village nurse midwife. Our village has developed in many ways with the help of Shanta and with the training from Shanta we are ready to maintain our development. If I can get one more chance to attend a new training for nurse and midwife, I would like to attend. Thank you so much!
Success Story of a Village Family
U Mone, 44 years old, lives in the village of Ga Naing Nge West, with his wife, Nang Loon, and three children.
Ten years ago their home burned down while they were away. U Mone is blind in one eye from an accident cutting bamboo. Up until two years ago U Mone was a carpenter but his 'company' dissolved and he no longer has work. He owns two small fields, where he grows cheroot leaves, but their value has plummeted over the past few years.
The family has faced difficult times in their life. However, U Mone feels like their luck is beginning to turn around because of Shanta Foundation. U Mone now has his own pig farm, which has the potential to triple his family's income! And, the family is really happy that Nang Kyi Htwe, their youngest daughter, is so bright that she was chosen by the village to attend Shanta's special boarding school. Nang Kyi Htwe is the "the sunshine of their family" because she is smart and studies hard. The family now has a lot hope for their future.
Success Story of an English Language Summer School Student
The following interview is the success story of English Language Summer School student Nang Phyu Phyu Win. She is a 14 year old, 9th grade student from Ta Khae village. Her parents are U Ohn Maung and Daw Nang Dit and they work hard as farmers to provide for Phyu Phyu (Pew Pew) and her younger brother. For the past two summers Phyu Phyu attended the Shanta Foundation English classes in her village.
Why did you attend this class?
I like to learn and speak English. Nowadays, people use English a lot (eg. notice boards, restaurants) and in television children are speaking English and I admire them. Also, when I see Myanmar people who are speaking with foreigner, I admire them and I imagine myself like that. So those thoughts push me to learn English more and I attend this summer class.
Was English a difficult subject for you before attending the summer classes?
It was a really difficult subject for me before. I found that grammar is very important for the lessons in the class but I didn't understand it well. I just studied to remember the sentence because I didn't understand well.
How did your English improve after you attended this class last year?
After last year, it is easier to learn English. Before I don't know verb, adjective, noun and couldn't understand them. And also I didn't understand how to use verb to be, verb to do, verb to have. But after the class I understood and learned many words. I can speak English a little bit now.
How did you feel about attending class this summer?
I'm very happy to attend and don't bore in the summer time. And I'm feeling thankful to Shanta for opening this class in my village and giving us a chance like that. If not, we don't have chance to attend English class because we have no money to go and attend class in town. We are so lucky to meet with wonderful teachers. They are really nice and we are playing games in the class without stress. They took us other places we've never been before.
Tell me about your changes and success after attending this class.
There are so many changes and successes for me. First thing is I understand English well and I got distinction in English public school classes. I've never dream to get distinction in English before and I just studied hard to pass. Next success is communication with people. In this class, teachers let us play games with the group, tell stories to get knowledge, and every student has to go in front of the class and talk either with a partner or by themselves. I was really shy to speak with adult people and boys before. And also I was shy to play and do homework together with boys before. I'm not shy anymore now and I have confidence to speak. These all are successes for me.
What do your parents say about this class?
My parents are feeling pleased. Especially my mom is happy. She didn't let me miss the class and told me to learn hard. She said that you don't need to go other place to attend and the class came to you. You are very lucky.
What do you want to do in the future?
I want to be an engineer. I also want to be a person who can teach English to the children.
Do you have any suggestions to improve English class?
I would like to say thank you to Shanta Foundation and teachers. I would like to advise all my classmates to attend this class. I want to attend class next year also. It will be better if the class can start early March to have more days learn. Thank you very much.
Changing the Face of Health Care Programs
Kham Law is changing the face of health care in Tee Lone village. As the village's auxiliary nurse-midwife, she has safely delivered all 12 babies born in 2012/13 and is currently providing prenatal care for seven pregnant women and general medicine for all adults.
Shanta's Village Nurse-Midwife Program trained the first generation of community health leaders in five of our Partnership Villages in 2011. These women have taken on the role of primary health provider for their entire village.
Dr. Nge Nge, our regional director, is also conducting monthly professional development sessions with the village nurse-midwives, reviewing their caseload and studying Where There is No Doctor, a valuable book on health care in remote areas.
Previously, untrained health workers would treat all medical complaints, often with outdated drug injections and no accurate diagnosis. Traditional birth attendants were not trained to handle delivery complications and offered no prenatal care. In February 2013, a staff member's sister-in-law died from complications from an abortion in Yim Bya village.
The Maternal Health Care Program includes:
- Prenatal exams
- High quality prenatal vitamins (donated by VitaminAngels)
- Safe childbirth support
- Contraception options
- Infant care
- Immunization management
Kham Law is amazingly confident, loves delivering babies, and is well-respected by her village elders. Plus, she is earning an excellent income.


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Caroline Fortuna EasterlitaFreelancer
About Me
Majoring in International Relations IUP UGM. Currently living in Tangerang, Banten. I am able to work under pressure with the time constriction and will work hard to get the job done precisely. Fluent in English as I've been joining several Model United Nations in national and international scale.
Job history and feedback provided by the client after completing the job
No reviews yet


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Private saxophone lessons
Teach you jazz, classical, or rock/pop saxophone over Skype or in person.
Training & Qualifications
I have a BM in jazz/commercial music from the Lamont School of Music at the University of Denver and have been playing professionally for over 8 years.
Availability & Preferences
About Aeryk Parker
I'm a musician, devoted to creating a better world with my contemporaries. I teach, train, and perform jazz, rock, pop, classical, and bluegrass music (among others). If I can do my part to show the w...orld that trade and barter are still viable in our society, I will be able to leave this world with a smile on my face.show moreOpen to other proposals
Aeryk Parker is looking for:
- Entertainment & Performance
- Photography
- Music & Audio
- Massage
- Travel
- Graphic Design
- Video & AV


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Facing TV Problems? Ask a TV Technician.
does it do this on all inputs? like DVD?
ok i closed out the other question. this is a easy fix. there are 5 wires that go from your cable box to your tv.one of them and i would guess the red one is not plugged in all the way either on the back of the box or the back of the tv. please check each one and push each one in and this should fix your issue.
i do not think it is a tv issue at all. check each wire from the tv to the box. each wire must be in the right place. i think you have one backwards. what i mean is you have three wires for video red blue and green. if you get two backwards then you will get a odd picture. unhook all three and re hook up red to red blue to blue and green to green.
I did that while I was waiting and I got it to work!!! Thanks so what do I owe you?
just click the accept button and we are good.
you are so welcome.


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It was first established as Rosetta Studio Workshops by ex-university lecturer, Yvonne Humble, in 1993 and based in a single classroom at Rosetta Primary School, Canning Town. It quickly expanded to a new location in 1995 at the Hamilton Road Centre, Stratford, which remains the home of Rosetta Art Centre today. In 2007 it was renamed Rosetta Art Centre under a new management.
From the outset Rosetta Art Centre focused on the visual arts education of local adults and whilst this remains a core activity today, the Centre delivers a far wider range of programs, activities and services to the community:
Working with a wide variety of local schools, Rosetta Art Centre delivers project work and after-school provisions both in-school through artist in residence initiatives as well as at the Centre itself.
School holiday programs such as summer schools and Easter break schools are offered every year, where a variety of activities and workshops are offered to local children and young people.
The Children's Saturday Art School offers a fun and engaging programme of activities, including gallery and museum visits and exhibition opportunities for Newham's young children aged 8-11 years old.
The Young Newham Artists project caters specifically for young people aged 16-24 years from Newham, offering them a unique space and environment to work on digital and mixed media collaborative projects, allowing them to develop their individual creative skills at the same time as achieving accredited qualifications and gaining an invaluable experience.
Our post-16 (adult) course provision covers a comprehensive range of visual arts, offering accredited qualifications at different levels and through different mediums. It also includes a number of non-accredited short courses.
We provide specific classes and workshops that are tailored to the specific needs of adults with learning difficulties and/or disabilities.
Weekend holiday courses for adults are delivered at Debden House, in the Epping Forest where you can book accommodation, catering and a weekend visual art course all together.


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Have anyone else tried the facebook messenger for windows os? =)
I think the UI is extremly basic and the chat/messenger is very messy. They are so clean that they are ugly
I think it's weird that facebook has made such a nice mobile app, messenger and that the website is acutally decent and then they create a messenger for an os used by millions that sucks


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|Nutrition facts:
| Amount Per 1 cup (146 g)
Calories 828 % Daily Value* Total Fat 72 g 110% Saturated fat 10 g 50% Polyunsaturated fat 23 g Monounsaturated fat 36 g Cholesterol 0 mg 0% Sodium 26 mg 1% Potassium 1,029 mg 29% Total Carbohydrate 24 g 8% Dietary fiber 12 g 48% Sugar 6 g Protein 38 g 76% Vitamin A 0% Vitamin C 0% Calcium 13% Iron 37% Vitamin D 0% Vitamin B-6 25% Vitamin B-12 0% Magnesium 61%
Peanuts can be a great value healthy food. They're legumes, related to Peas beans lentils. Peanuts are (at least in the UK) cheaper than other nuts but also higher in protein. peanuts can be eaten raw or added to stir fries. Peanuts work in Vegetarian stir fries or stir fries that include meat.
If you're poor it's worth remembering that peanuts, milk and other cheap, high protein foods can help keep you healthy without overspending. You don't need foods rich people eat like beefsteak to keep fit. Perhaps you're a student, you want to buy all the textbooks your lecturers recommend but don't like getting into debt. Perhaps you're saving for a mortgage, struggling to repay a mortgage. Whatever the reason if you need to live economically peanuts are worth remembering. [1]
Even better off people sometimes like the taste and enjoy eating peanuts.


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TRACKGRAM For PC Online Free Download And Install
TRACKGRAM For PC Online Free Download And Install-Once again we are going to share a awesome apps/game- TRACKGRAM. If you want to play/use online TRACKGRAM on your PC/Computer then get ready for this. TRACKGRAM is awsome apps/game.
Lots of android users are enjoying by using this apps/game on their android smartphone. If you have not android smartphone, then don't worry . We are here to help you to play/use online TRACKGRAM on PC/Laptop on any OS like as Windows Xp/7/8/10 And MAC.
Here we will explain all the topic related to DR. TRACKGRAM for PC:-
Download TRACKGRAM On PC
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Free Download TRACKGRAM
TRACKGRAM APK Download
We are going to cover all of these topics. Just read all of this post and get ready to Play/use this apps/game on your computer.
TRACKGRAM For PC Online Download And Install
Its very easy, just keep reading carefully then you will understand whole method. Just read how to Play/use TRACKGRAM On PC Online:-
Step 1- First it will be needed a best Android Emulator. We can not use TRACKGRAM Online on PC without Android Emulator.
Step 2– So we will suggest to use Bluestacks, which is a best Android Emulator. Its very easy to use and handle.
Step 3- Now just download Bluestacks and install it on your Computer/PC. If any problem then just comment your problem here.
Step 4- After that start Bluestacks and just go on search option. Search there- TRACKGRAM.
Step 5- Now just Download and install TRACKGRAM on Bluestacks.
Step 6- Just double click on TRACKGRAM icon and it will be start. Now play/use onlinje TRACKGRAM on PC.
Its done TRACKGRAM For PC Online.
TRACKGRAM For PC Online Features
– Keep track of new Instagram followers & unfollowers
– Find out who blocked you and block back
– Search users and hashtags for new people to follow
– Support your followers by liking their photos in TrackGram
– Follow & unfollow inside the app
– Keep track of likes you receive and give
– Find the users who liked you most and the ones you liked most
– Find ghost followers who did not liked or commented on your posts
– Find the users to which you are a Ghost
Its completed. Now you can use this awesome apps/game on your computer/pc. Just play/use Online TRACKGRAM On PC. If you have any queries related to TRACKGRAM For PC then just give a comment here, we will try to solve all of your problems. So enjoy TRACKGRAM For PC Online.


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Marsha May – Push Ups Or Squats
Released: July 8, 2016
Mr. Nomar is keeping Marsha after gym class for some extra instruction. He has her do some push ups but she can't quite do them, her tits are just too big! Next he gets her to squat – better, but still not good enough. He tells this slutty student she's in danger of failing gym because she's not active, so she shows him how active she can be by fucking him.
Spare link: (try when other links are dead)


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It only takes a minute to get started. Fill out our simple sign up form and login to the site.
This step is voluntary but will seriously multiply your chances of getting interest from other Christian members on the site. Write a little something about yourself, your pasttimes and upload your nicest photo of yourself.
Utilise our website's cutting-edge search to discover members who suit your needs. Or just leaf through listings of Christian singles and discover people that arouse your interest.
Located someone who looks like a good match? Send them a few words or just a wink and see if they're interested. With a little luck you'll be on your way to uncover that special someone for you.
It'll only take 30 seconds


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It only takes a minute to get started. Fill out our simple sign up form and login to the site.
This step is up to you but will greatly boost your chances of getting interest from other over 40s members on the site. Introduce yourself, your interests and upload some good photos of yourself.
Utilise our website's cutting-edge search to find over 40s members who fulfill your criteria. Or just flip through listings and find folks that appeal to you.
Discovered someone who is attractive to you? Send a note to them or just a wink and await their reply. With a little luck you'll be on your way to true love.
It'll only take a few minutes


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Mom appeared on Sean Hannity's show recently to explain what she meant when she said she was interested in running for President. [Read more…]
Will She? Won't She? Sarah Palin Explains Her Comment about Being Interested in the Presidency
What Party Affiliation is the First Black Senator Elected in South Since Reconstruction?
You guessed it. [Read more…]
Congratulations, Gov. Walker!
Last night was a reminder that the media doesn't decide who runs our country, the voters do. For the past 18 months, the "lamestream media" has led us to believe a rogue governor has been defying the will of the people. In fact, the Wisconsin governor was doing the work of the people. In fact, he was doing exactly what the voters elected him to do.
Last night was one to savor, because a good man doing good things won.
Congratulations, Gov. Walker, and thank you, Wisconsin!
You might also enjoy:
- Hail to the Chiefs: Malia and Sasha Obama
- Hate in the Name of Love, Bullying in the Name of Tolerance
- What's Better than Being a Palin?
- I'm No Victim
- On this one, I'm Team Hillary
- Mr. President, When Should I Expect Your Call?
- A Mom's Love for Her Child, One Paper at a Time
- Defending the "Palin Pick"
Connect with me further by:
A Few Thoughts about Rick Santorum Suspending His Campaign
Just now, Rick Santorum suspended his Presidential campaign, after a weekend at the hospital with his three year old daughter Bella. As you probably are aware, Bella was born with Trisomy 18 — a genetic disorder similar to Down syndrome that's caused her short life to be an ongoing battle.
No matter who you support for President in 2012, you have to admire how Sen. Santorum champions life – he fights for it in Washington and he fights for it in his own home, day after day.
As he suspends his 309 day campaign, let's honor his pro-life conviction by watching this touching campaign video. No, he doesn't have a campaign anymore, but we'll never stop the fight for life.
Leave a comment below to receive weekly updates, including the best of this blog. You may also enjoy:


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Romance, daring — and above all else, adventure. Riding through the cobblestone streets of Paris, model Martha Hunt embraces a very Parisian love affair with her beau, visiting the famed Love Lock Bridge in Paris to seal the deal.
"In Paris, the city of romance, you see how everyone - young and old, women and men - express their love by fixing a padlock on a bridge and then throwing the key in the River Seine while wishing for eternal happiness and love," describes Swarovski Creative Director, Nathalie Colin.
For the shoot, influencers Margaret Zhang and Martha Hunt juxtapose Swarovski jewelry with bold moto accessories. Martha layers the Give Collection Evil Eye pendant with a leather jacket, Strandage Bars and Attract earrings, creating a look that is both lovely and laid back.
A darling white lace top receives a rocker touch when combined with a Vittore Palm Cuff and a smattering of Field Rings. Martha embraces symbol with butterfly, moon, and heart Field Rings lending a romantic whimsy to the mood. Shot by Margaret Zhang, Martha brings an effortless, feminine French touch by combining Crystal Wishes' delicate and thin pieces with a low-key, casual glam.
Martha Hunt by Margaret Zhang


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Jaguar Repair Problems? Ask a Jaguar Repairs Expert.
Hello and welcome to justanswer.com
Any shop can do an oil change for you as it's pretty simple. Depending on your year the 60,000 mile service consists of an oil/filter change, air, fuel, pollen filter, wipers and some general checks and inspections. My dealer charges about $650.00 for this service. The problem with a Jiffy lube is that they will change the oil and sell you some filters but they really will not look over your vehicle for any other things that may be a potential problem.


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New Bingo Sites I July 2017
- The best new bingo sites from the last 12 months. With exclusive offers such as £5 deposit , free slots and mobile bingo offers
- Big deposit bonus offers and exclusive promotions
- New bingo sites, some with no deposit required
- All UK regulated
Bringo Bingo
Bringo Bingo is a Dragonfish / Cassava / 888 bingo site from Ignite, the people behind Costa Bingo. Themed on a fictitious TV quiz…
Queen Bee Bingo
Queen Bee Bingo is a brand new bingo site on the new Dragonfish Real Bingo Network. If you haven't come across this network before,…
Lucy Bingo
Lucy Bingo is a Dragonfish bingo site with big deposit bonus offers on all deposits (especially the first three). A sister site to
Good Day Bingo
Good Day Bingo is a Dragonfish network bingo site which launched with probably the most generous set of welcome and ongoing bonus offers yet seen…
Bingoroo is a stunning new Dragonfish bingo site that really stands out amongst the recent launches on the network. The kangaroo theming has been beautifully…
Rewind Bingo
Rewind Bingo is powered by Dragonfish and is the most recent bingo site launch by Ignite/Mandalay Media, the people behind Costa Bingo and a…
Real Deal Bingo
Real Deal Bingo is a Dragonfish bingo site but unlike the majority of launches on the platform it is not on the original Dragonfish…
Bid Bingo
Bid Bingo was originally Yahoo Bingo and is now been completely reinvented as a Dragonfish network bingo site. It has all the usual network…
Big Tease Bingo
Big Tease Bingo is a Dragonfish powered bingo site but unlike the majority of such sites it is NOT on the Dragonfish network. Instead,…
Give Back Bingo
Give Back Bingo is a charity bingo site on the Daub Alderney platform (also used by Kitty Bingo and sister sites) which…
New bingo sites - what to expect in 2017Regulatory and tax changes continue to have an impact on the world of online bingo - here's what we think may be coming in 2017 (and here's how our 2016 predictions actually worked out)
- Bonuses an endangered species
- Offers given to existing players as well as new ones
- Short bonus expiry times
- Free bingo under threat
- More inventive existing player promotions
- More mergers and acquisitions creating a marketplace with fewer bigger players
- UK CMA to crack down on unfair terms and conditions
- UK GC to bring in tougher enforcement policy
- Further regulation of advertising
- UK ICO crackdown on spam emails and texts
- Brexit related industry worries
- The clock is ticking for Flash
- Even more big link bingo
- Even less charity bingo
- The decline of chat
- More new bingo variants
- More focus on slots
- Increasing use of social media for promotions
Bonuses an endangered speciesHMRC have recently finished gathering responses to a consultation about the taxation of free bets. This was carried out as a result of the proposal in the 2016 Budget to bring the tax treatment of online free bets - including bonuses and free spins - in line with that in betting shops and other land based venues. The new regime is scheduled to come into force in August 2017 and essentially it will mean that online bingo operators (and other online gambling operators) can't offset the value of bonuses they give out against their profits for tax (only the value of cash winnings from the bonuses). As a result of the consultation a concession has been made for bonuses which carry a wagering requirement, so that only the initial use of the bonus and the eventual winnings after the wagering requirement has been completed will count for tax, and the intermediate playthroughs and winnings will not count. In the case of some operators that have a history of giving out enormous bonuses, however, this could still result in a much bigger tax liability than they currently have - if they continue to hand out bonuses at such a rate. Indeed, the new taxation rules are expected to bring in over £300 million for the Treasury in the first four years (although of course this will not all come from bingo sites). We were already seeing the decline of automatic redeposit bonuses and this is likely to hasten their end. Redeposit bonuses these days tend to be given out as part of specific time limited promotions and/or offered to selected players only via text or email. For example, redeposits at Foxy Bingo used to attract an automatic 50% bonus but now they give none (and this caused a lot of people to get quite angry on their Facebook page). To collect bonuses at Foxy these days you need to visit the site often, pay attention to the emails they send you, read the free magazine they send out in the post and watch out for their messages on social media. Giving bonuses out like this also enables bingo sites to give out fewer bingo bonuses and more slots bonuses.
Offers given to existing players as well as new onesThis has been going on for a long time, of course, but as far as bingo bonus offers are concerned the offers to existing players were a pale shadow of those for new players. In the summer and autumn of 2016 a trend started at Virtue Fusion sites whereby a no deposit bonus was made available to all players, old and new. The twist was that the £10 wasn't given out in one go, but over a week or so as 5 lots of £2, each of which had a 48 hour expiry - so players had to keep coming back and playing instead of going off to take up a welcome bonus offer at a new bingo site instead. We expect to see more of this kind of thing. We also expect to see more of the type of promotion which awards a bonus based on an amount of cash play rather than requiring a deposit.
Short bonus expiry timesThe majority of bingo players probably have a few bingo accounts they play with occasionally, that have some leftover bingo bonus in them. If a bonus never expires, there is no urgency to use it up, nor is there any urgency to play through a cash deposit in order to get access to the bonus (as most sites use cash before bonus, the bonus won't be used for ticket purchases if there is any cash in the account). Not only are many more bingo sites now imposing a time limit, but these are getting shorter and shorter; 30 days used to be common but now it is often 7. Let's say a player signs up to a new bingo site, deposits £10 and gets a £30 bonus. If cash balance is used for ticket purchase before bonus, and the bonus expires in 7 days, that means that in the first 7 days of play at the new bingo site the player has to play through the £10 and any cash winnings from the £10 before they can even get started on the £30. A new player who takes a while to find their way around the site, or is lucky enough to win early on, may run out of time to use the £30. Similarly a player who has cash in their account and gets an extra free bonus via a promotion, will be unable to take advantage of the bonus before it expires unless they first spend all their cash. While this is extremely annoying for players, it is clearly beneficial for the bingo sites as it encourages the players to spend more money faster.
Free bingo under threatThe new taxation regime is also set to have an impact on some free bingo games. As long as the tickets are free to everyone the position won't change, but in the case of a game where some tickets are paid, tax will be payable on the free tickets based on the face value of the pay tickets. Games that could be affected include the Cozy free bingo room where extra tickets can be bought for 1p each and the Dragonfish network Big £10K, where tickets are given away free to depositors but can also be bought for £10. It is not clear whether that Virtue Fusion favourite, Free or Superbooks, will be affected; we think perhaps not as the pay tickets in these games have different prizes to the free tickets.
More inventive existing player promotionsIf there are to be fewer bonuses on offer bingo operators may seek to attract and retain players by running other types of promotion instead. Prize bingo games and prize draws with cash or tangible prizes are an obvious alternative and some other possibilities are multi-level games and escalator jackpots.
More mergers and acquisitions creating a marketplace with fewer bigger playersThis is going on at both ends of the market. At one end we have the two new megabookies, Gala Coral Ladbrokes and Paddy Power Betfair. The five bingo sites retain their individual identities but now share bingo rooms and promotions with the other sites that are part of the same organisation. At the other end of the market we have the ongoing acquisitions activity of 8 Ball Games (who have hoovered up many a small bingo site) and their purchase by Stride Gaming. It's not confined to the online bingo arena either; Playtech recently bought ECM Systems who provide electronic systems for use in bricks and mortar bingo halls.
UK CMA to crack down on unfair terms and conditionsThe UK Competition and Markets Authority is the latest government organisation to put the boot in to the world of online gambling. The investigation started in the autumn of 2016 and we have yet to see what the conclusion will be, but it is based on concerns raised by the Gambling Commission about "potential breaches of consumer law, including misleading promotions and unfair terms, being used by firms to block players' payouts" or in the words of the Gambling Commission's Chief Executive "concerns that many of these (operators) appear to bamboozle rather than help the customer make informed choices". "Complex and strict requirements...that are difficult to understand and may be unachievable" and "terms that require people to play for longer than they had bargained for before they can withdraw money" are some of the things being investigated and this almost certainly refers to excessive wagering requirements and other withdrawal restrictions. There are certainly many bingo sites that could do with cleaning their act up in this respect. Another result of this could be the launch of new bingo sites such as Blighty Bingo which do away with bingo wagering requirements entirely by offering different types of player incentive instead of a bingo bonus.
>UK GC to bring in tougher enforcement policyThe Chief Executive of the UK Gambling Commission, Sarah Harrison, made a speech in November 2016 outlining her vision of the future of the UK gambling industry as the most trusted and respected in the world, with customer service rivalling that of John Lewis. As well as upping their game on social responsibility and the prevention of money laundering, the GC is concerned about whether operators are treating customers fairly. They have seen an increase in the number of complaints of over 300% in the last two years, receiving over 40,000 emails and nearly 37,000 phone calls in the 12 months immediately prior to the speech being made! The top areas of concern are:
- self exclusion
- withdrawal of customer funds
- terms and conditions
- advertising and marketing
Further regulation of advertisingFor quite some time now, gambling adverts on TV have been restricted till after the 9pm watershed but there are exceptions for bingo site adverts and sports betting adverts during televised sporting events. At the beginning of 2016 a further restriction was put in place meaning that all ads must end with a socially responsible gambling message and welcome bonus offers cannot be advertised until after the 9pm watershed (this is in addition to all the already existing rules about content banning anything likely to appeal to children, featuring anyone under 25, suggesting that gambling is stylish or a route to riches, etc etc). Rumour has it that a total ban on pre-watershed gambling advertising is in the pipeline and if it is we should hear about some time in 2017. The Daily Telegraph has speculated that this could also apply to social media and it would be logical then for it to be extended to other online advertising including YouTube.
UK ICO crackdown on spam emails and textsYet another UK government agency is going after the gambling industry! This time it is the ICO (Information Commissioner's Office) which looks after data protection, and what they are seeking to tackle is unwanted communications to players - emails, texts and sometimes even phone calls from operators themselves and from third parties to whom the contact information has been passed without the consent of the player in question. This initiative has a very long way to go before it becomes effective but even a small reduction in the spam problem will be very welcome.
Brexit related industry worriesSeveral months on from the Brexit vote, there continues to be a question mark over the future of Gibraltar. The only thing that is yet clear regarding the manner and timing of the UK's departure from the EU is that it could take years before everything is properly sorted out! Gibraltar is important to online bingo as it is where many operators including 888 were licensed in the days of the whitelist, and are still at least partially based. Not knowing how cross border trade and employment would work (if at all), plus worries over Spain attempting to gain influence or even take over, is extremely unsettling for operators with bases of operations there. Another important base of operations for the industry is Malta and although one of the official languages spoken on the island is English and there is a sizeable British expat population, the republic of Malta is part of the EU as a country in its own right. At the moment it is easy for UK nationals to move to and/or do business on Malta (albeit more expensive than previously, due to the weakness of sterling) but after Brexit this is likely to become difficult or even impossible and in the case of a super hard Brexit, UK nationals currently based on Malta might be unable to stay there! Again, this prospect is extremely unsettling for bingo site operators. Although none of this will have any immediate and direct effect on online bingo, operators with Brexit related jitters are likely to keep a close watch on operating costs and profitability which could translate into fewer bonuses and freebies for players and fewer new bingo sites to play at.
The clock is ticking for FlashShockwave Flash is a technology that has been (albeit slowly) on the way out for years now, ever since Steve Jobs decided never to support it on Apple devices. but now it really is the beginning of the end for Flash. There are many reasons why Microsoft, Apple, Google and Mozilla all dislike Flash and these include its vulnerability to hackers, its lack of cross platform support, its slow speed and its tendency to crash. 2017 looks set to be the year when Chrome and other browsers remove support for Flash. This is a BIG problem for online bingo because many bingo sites still require Flash to work (apart from on mobile and tablet where it isn't supported)! The replacement for Flash is HTML5 and some bingo sites have already moved on to it (or never used Flash in the first place). Already on HTML 5: Jumpman (although some of the slots are Flash and the mobile bingo is barely worthy of the name), Cozy, Relax Gaming, Virtue Fusion/Playtech (not all sites), Bede Gaming Still wholly or partly on Flash: Microgaming, 888/Dragonfish, Daub, B-Live, Gamesys. At the end of 2016, Virtue Fusion's move to HTML5 had been under way for the best part of 18 months but many Virtue Fusion bingo sites were still on Flash and most of the ones that had migrated to HTML5 still offered existing players the option of using the old Flash lobby . The upgrade is taking a long time to complete, exacerbated by some considerable player resistance to the new style lobby and bingo rooms. The HTML5 version loads much faster but was launched without many of the features of the Flash version and with a restricted selection of slots and this was unpopular with players. The Flash bingo platforms all have non Flash mobile versions (although in the case of Gamesys not all the rooms are available) but - as we have seen with the Virtue Fusion migration - integrating them on to the desktop is not a quick and easy job. 888 have been rumoured for some time now to have a move to HTML5 in the pipeline and we expected this to materialise when the new version of the Dragonfish/888 software (including Flash Fives) was released in summer 2016 - but the new version (as found at Foxy Bingo, Costa Bingo and many other sites) turned out to be Flash based. 888 could now be running out of time to get their move to HTML5 completed before support for Flash disappears entirely - and because of the sheer number of sites on the platform they really need to get it right first time to avoid massive disruption across the industry. Indeed, some 888 powered sites have already taken steps to do something about this looming problem - basically by introducing some kind of workaround. Foxy sent an email to their players at the beginning of December 2016 explaining how to re-enable Flash pop-up games that no longer run automatically in the Chrome browser, and the Costa Bingo group of sites, at roughly the same date, started to offer players a choice of the Classic Lobby or the Tablet Lobby (the latter choice serves the HTML5 mobile version to the desktop). UPDATE: We are now seeing new Dragonfish bingo sites launch with the Tablet Lobby as standard and no Flash lobby, so this may be the sum total of what they are planning to do about migration.
Even more big link bingoBig link bingo games bring together players from different networks and give players access to high variance bingo - where the chance of winning is much smaller than in a normal bingo room but the prizes are much bigger. We expect to see these games continue to flourish but, rather than big games with huge guaranteed jackpots that can go very wrong for bingo operators if they fail to sell enough tickets, more along the lines of the 888 big link rooms that run across several networks every evening.
Even less charity bingoThe decline of charity bingo has been caused by the squeeze on bingo operators' profits resulting from regulatory and tax changes and as already discussed more of these are coming. A new charity bingo site - Give Back Bingo - did launch right at the end of 2016 with the modus operandi of a monthly donation (guaranteed to be at least £500) to a nominated charity. This has been tried by various other sites and never worked consistently, and it remains to be seen whether Give Back Bingo can get it right where others have failed.
The decline of chatChat has always been one of the things that makes the online bingo experience special, but at many bingo sites it now seems to be in decline. For example, at Cozy sites, although the rooms were networked, there used to be different chat and a different chat host in each room and now there is one chat channel linking all the rooms together. At Dragonfish, and at 15 Network, many rooms are no longer hosted at all (especially during the daytime). The more chat rooms a site has and the longer they are open each day, the more chat hosts the site needs to employ altogether to ensure all are covered - and unless the bingo site has non network bingo rooms or is on the Virtue Fusion platform, it is not the site operator but the network provider that makes the decision as to whether this is worthwhile. It's not just a matter of paying the chat hosts, either - players expect there to be chat games in hosted rooms (and there may be very little player participation in the chat without them) but the bonuses and loyalty points that are typically given out as chat game prizes at bingo sites represent a further cost. Certain bingo networks also used to be able to keep the cost of the chat down by employing chat hosts based in other countries but this is no longer so effective because of the collapse of sterling after the Brexit vote. Given that an increasing number of players are now playing mobile bingo via their phones (and presumably this is also more likely to be the case in the daytime than in the evenings) which makes it much harder for them to participate in or even keep track of the chat, Cozy, Dragonfish and 15 Network have clearly decided that full chat coverage of their bingo sites is an unnecessary expense. Our view is that cut price chat is not really much better than no chat at all and that it is better to concentrate on getting high quality hosting for busy times when there are lots of players around - and also that network chat can never be in the same league as the sort of site specific chat you find at big Virtue Fusion bingo sites such as Sky Bingo, Sun Bingo and bet365 Bingo, or at non network sites like Bingo Hollywood. Nor do we expect to see any new bingo sites launching which can rival the aforementioned big Virtue Fusion bingo sites as far as the quality of the chat goes; to set up a high quality team of UK based chat hosts would require a big initial outlay which the majority of entrants to the market would be unable to afford.
More new bingo variantsThe last time Virtue Fusion came up with a completely new bingo game was Cash Cubes last February. While several new Virtue Fusion bingo games have come out since then these have been regular bingo with an extra bonus game (e.g. The Chase Bingo), a variation on an already existing game mechanic (e.g. Mystical Bingo at Sky and Bingo Bowl at William Hill both of which are 50 ball) or a VF version of a game from another platform (Royal 5s at Mecca which is basically Cinco). The most probable time over the next year for them to announce a new variant would be at the ICE Totally Gaming show in February (which is where Cash Cubes made its first appearance last year). UPDATE: A new variant was indeed launched at ICE (Bouncy Balls Bingo) but it is essentially a re-skinning of Cash Cubes. A further variant appeared at Sky Bingo a couple of months later; Tipping Point Bingo adds an exciting visual twist to the Rainbow Riches Bingo game engine and comes with an innovative matching slot and scratchcard. Flash Fives / Bingo Vegas was the last variant 888 introduced and it is still not at very many sites, so we would expect to see it propagate further rather than anything else launch (especially since the 888 technical team are presumably busy working on an HTML5 migration plan). Rather than new variants, we could see more Dragonfish/888 games offering free slots spins as prizes, like the ones at Iceland Bingo.
More focus on slotsWe don't just expect to see bingo sites adding new slots as they come out. We also expect to see:
- Bingo sites extending the range of providers they get slots from - as the Jumpman sites did towards the end of 2016 when they began to feature NetEnt slots
- Bingo sites offering more slots bonuses and free spins and fewer bingo bonuses - as already seen at a number of sites including Foxy Bingo and of course the Wheel of Slots bingo sites


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mlkennedy Review
High quality earrings.
These are lovely earrings. Reasonably priced, very attractive and they hang beautifully. And the money goes to support women in business overseas. A win-win!
- Did the color match the color displayed onsite? yes
- How is the quality of the product? Very good
- Did the product fit true to size? n/a
Was This Review Helpful?


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July 22, 2008
ARVE Error: no id set
One storm that we're looking forward to this hurricane season is DJ Laz's Catergory 6 album with features by T-Pain, Rick Ross, Pitbull, Flo-Rida and others. Soon after dropping the first single "Move, Shake, Drop" with Pitbull, he dropped the remix version with Flo-Rida, Pitbull again, and Casely. Here's the video, which was directed by David Rousseau for CreativeSeen.
CategoriesArtist Spotlight


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|Message view
|« Date » · « Thread »
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|Paul Elschot <paul.elsc...@xs4all.nl>
|Re: RemoteSearchable will not work anylonger, due to changes in BooleanClause
|Sun, 29 Aug 2004 20:33:23 GMT
On Sunday 29 August 2004 19:55, Daniel Naber wrote: > On Saturday 28 August 2004 17:16, Bernhard Messer wrote: > > Just change the constructor to: > > public static final class Occur implements java.io.Serializable { ... > > Thanks, I did that. However, TestRemoteSearchable doesn't work for me and > it didn't even work before my changes. In Eclipse I get a > StubNotFoundException. With "ant test" TestRemoteSearchable just hangs (no > CPU usage). I guess this is a problem with the network configuration in > Suse 9.1 because I get a "Network is unreachable" error with "ant test" > when I'm not online. Fwiw, on current CVS head, after ifdown eth0 on Suse 9.1 I also get Network is unreachable errors from ant build.xml -Dtestcase=TestRemoteSearchable test After ifup eth0 the test passes normally again, no hangs at all. java -version is 1.4.2-b28 Regards, Paul Elschot. --------------------------------------------------------------------- To unsubscribe, e-mail: email@example.com For additional commands, e-mail: firstname.lastname@example.com
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Keegan and Thatcher is a fan-fiction TV Show created by Pikachufreak.
- The show resolves on Keegan (from The Stolen Stones) and Thatcher (from A Different Kind of Misty and Cheer Pressure) the main characters. Their older sisters are Ramona (also from The Stolen Stones) and Alyssa (also from A Different Kind of Misty), their girlfriends are Cherry (from The Psychic Sidekicks) and Calista (from Me, Myself and Time), their best friends are Malachi (from Carrying On) and Maxx (from Maxxed Out), their older brothers are Gan Gogh (from The Light Fantastic) and Chaz (from All Things Bright and Beautifly), their rivals are Koji (Ramona's total crush, from Good Quil Hunting) and Rico (Alyssa's total crush, from A Poached Ego) and their mothers are Naomi (from Lapras of Luxury) and Yuma (from What I Did For Love). The Series premiered on March 1, 2004 and is currently in its 8th Season.
- Keegan
- Thatcher
- Ramona
- Alyssa
- Cherry
- Calista
- Malachi
- Maxx
- Ramonita
- Tia
- Koji
- Rico
- Naomi
- Yuma


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Elwyn is a shy little girl who likes other dogs but is still getting used to being around people. She can take some time to warm up to new people, especially, but she is starting to learn to trust. She is walking on the leash, and is a curious girl who likes to explore around the back yard and new places. This seven-year-old girl is food motivated, which helps with training and teaching her that people = good things! We haven't heard her make a lot of noise yet, but that doesn't mean she won't find her voice soon – she is a beagle after all! Shy dogs like Elwyn often do better when there is another confident, friendly dog in the home. She probably would not be comfortable around small children or in a busy house with lots of commotion, as she can be skittish with loud noises and fast movements. She will need a very special, calm, and patient home to help her work through her fears, but we're pretty sure she'd make it worth it!
*Elwyn is currently in a foster home in Lafayette, CO. You can get more about information meeting and adopting a dog from foster by contacting us using the information below.
Entered this great big world on: 11/27/09
Living the sanctuary life since: 1/31/07
Involved in research for: drug studies
Living the sanctuary life since: 1/31/07
Involved in research for: drug studies


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Madness - One Step Beyond MP3
Madness - One Step Beyond.
One Step Beyond - Encounter MP3
Encounter - Air date: April 12, 1960 Season 2 Episode 29 A small construction crew is set on edge when a pilot and his plane suddenly disappear, his last radio ...
Madness - One Step Beyond MP3
The song that provides the opening salvo to Madness' 1979 debut album of the same name. Who can forget the first time they heard the immortal, booming ...
One Step Beyond (Night Of The Kill) MP3
One Step Beyond (Night Of The Kill) Season 2, episode 5. Air date: October 20, 1959 After being missing from home young Davey Morris tells his parents he was ...
One Step Beyond- The Secret MP3
In this episode, a woman is befriends a man who died long before she was born.
One Step Beyond - Earthquake MP3
In this episode, a bellhop foretells The Great San Francisco Earthquake of 1906.
One Step Beyond - "The Day The World Wept: The Lincoln Story" - FULL EPISODE MP3
One Step Beyond - "The Voice" - Syndicated Episode. MP3
A heavily edited episode unfortunately but it's the only copy I have. Just thought it should be out there anyway. Enjoy!
One Step Beyond - The Vision MP3
One Step Beyond - The Vision.
One Step Beyond- The Explorer MP3
Three lost explorers wander aimlessly in the desert. Suddenly from out of nowhere, a man appears to lead them back to civilization.
Madness -- One Step Beyond [[ Official Live Video ]] HD MP3
Madness -- One Step Beyond :: Live At The iTunes Festival 2012 :: Madness:: Lyrics :: Hey you, dont watch that Watch this! This is the heavy heavy monster ...
One Step Beyond- Brainwave MP3
In this episode, a ship's captain is gravely injured. The Pharmacist's mate must perform the surgery by communicating with a nearby ship's Medical doctor.
One Step Beyond- The Visitor MP3
In this episode, years of bickering have brought Ellen and Harry Grayson to the final argument of their marriage.
One Step Beyond- Where Are They? MP3
In this episode, a man discovers effervescent tablets that turn water into fuel for automobiles.
One Step Beyond (Reunion) MP3
One Step Beyond (Reunion) Season 2, episode 10. Air date: November 24, 1959 The setting is Germany in 1939 and a group of young glider enthusiasts are ...
One Step Beyond -05- Twelve Hours to Live MP3
Many famous and some not-yet famous actors appeared in episodes of the series, including the following: Donald Pleasence ("The Confession"), Anton Diffring ...
One Step Beyond- Night of Decision MP3
In this episode, the Continental Army is camped at Valley Forge and Washington is debating whether to surrender to the English.
One Step Beyond - "The Sacred Mushroom" - FULL EPISODE MP3
One Step Beyond- Echo MP3
A man is found innocent of his wife's murder. When her brother arrives from New Zealand he foresees the real culprit's capture.
One Step Beyond - Forked Lightning, Full Episode MP3
Originally Aired: November 17, 1959. A lightning storm sets mysteriously causes to men to meet their fate. Watch Full Length horror movies on ...
One Step Beyond - "The Lonely Room" - Syndicated Episode MP3
A heavily edited episode unfortunately but it's the only copy I have. Just thought it should be out there anyway. Enjoy!
One Step Beyond - The Navigator part 1 MP3
This is one of my favorite shows and lucky for you the company neglected to renew the copyright. So since this show is now public domain there have been a lot ...
One Step Beyond - "If You See Sally" - FULL EPISODE MP3
One Step Beyond - The Captain's Guests MP3
A sadistic sea captain from the 19th century haunts a New England home and poisons the lives of a married couple. I am building a wiki that will archive all the ...
One Step Beyond- The Last Round MP3
The ghost of a prize fighter haunts a boxing arena. Legend has it that you will die if you see him.
One Step Beyond - "The Death Waltz" - FULL EPISODE MP3
With Elizabeth Montgomery. Enjoy!
One Step Beyond- The Inheritance MP3
In this episode, a possessed diamond necklace inflicts horrific punishment on the women who try to wear it.


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The fire, which was suspected to have originated in the electrical department in the basement of the centrally air-conditioned building, swiftly spread, with the third floor and above being affected the most, fire brigade sources said
Kolkata: At least 73 patients suffocated to death when a massive fire broke out in a centrally air-conditioned seven-storey private hospital in the metropolis today, reports PTI.
Police and hospital sources said 73 people had died in the fire at the private 190-bed AMRI Hospital at Dhakuria in the southern fringes.
The fire in the annexe building of the hospital was detected at around 3:30am by local people who rushed to the gates, but were driven away by the security guards, following which the fire spread swiftly, West Bengal urban development minister, Firhad Hakim, said.
As smoke billowed out, firemen using ladders with platforms smashed the window panes in the facade of the building to rescue patients trapped inside the ICU, ICCU, intensive therapy unit and critical care units.
The firemen evacuated the patients with pulleys from the upper floors as they were not in a condition to be taken down by ladders put up by the fire brigade all around the building.
The fire brigade had difficulty in entering the hospital premises as the approach roads were narrow, he said.
Additional director general, fire services, D Biswas, said that the fire brigade was informed at 4:10am and responded immediately.
He said that patients who died, were admitted in the critical care and orthopaedic units, and were unable to move.
He said if proper fire fighting arrangements existed at the hospital, such a fire could not have taken place.
Chief minister, Mamata Banerjee, who visited the hospital, ordered cancellation of its licence. She urged the angry relatives of the victims to go to the state-run SSKM Hospital to identify the bodies.
Disaster management minister, Javed Khan, told PTI that the National Disaster Response Force team would be arriving shortly to determine if there was radioactive leakage from the oncology department.
Senior vice-president of AMRI, S Upadhay, said there were 160 patients in the annexe building at the time of the fire.
Mr Upadhay claimed that the hospital followed strict fire safety measures and conducted regular fire drills. "All statutory safety and fire licences are in place."
He announced Rs5 lakh as compensation for the next of kin of those who died, while those injured would be treated free at the hospital.
Of the 46 bodies, 42 were taken to the SSKM, two to the AMRI Salt Lake and one each to AMRI Mukundapur and state-run M R Bangur Hospital.
The disaster management minister said that the chief minister had directed lodging of an FIR against the AMRI Hospital authorities. The state government has ordered an inquiry into the incident.
Mr Hakim said that 250 firemen in 25 fire engines battled the blaze and smoke with a police cordon thrown around the hospital.
Family members of patients vandalised the reception counter, aggrieved that no list of the dead and injured was provided. They smashed the glass panes at the reception and threw away hospital registers.
Governor, MK Narayanan, expressed shock and hoped that the state government would take necessary steps to identify the cause of the fire and initiate appropriate action.
In his letters dated 2nd June and 20th July to TKA Nair, then principal secretary to the prime minister, Satyananda Mishra had expressed anxiety over growing backlog of cases at the Commission due to the existing vacancies and said that Right to Information would become 'pointless' if a citizen had to wait for over a year to get information
New Delhi: Expressing concern over piling up of cases due to vacancies at the Central Information Commission, Chief Information Commissioner Satyananda Mishra has asked the government to stick to the provisions of RTI Act in filling up vacancies on the transparency panel, reports PTI.
In his letters dated 2nd June and 20th July to TKA Nair, then principal secretary to the prime minister, Mr Mishra had expressed anxiety over growing backlog of cases at the Commission due to the existing vacancies and said that Right to Information would become 'pointless' if a citizen had to wait for over a year to get information.
The letters have now been made available to one Amit Shanker of Varanasi under the RTI Act.
The Commission which should have a Chief Information Commissioner along with 10 Information Commissioners as per the RTI Act has only six members including Mr Mishra and faces over 21,000 pending cases even as the last appointment of information commissioner was done two years ago.
The Department of Personnel and Training had invited applications for the post of Information Commissioners at the CIC through a circular dated 29th October 2011.
In his letter to then principal secretary to the prime minister TKA Nair on 2nd June, Mr Mishra had said that the RTI Act itself has laid down procedure for appointment of information commissioners and any new method is 'redundant'.
"The RTI Act itself lays down the procedure for appointment of information commissioners. It is the selection committee headed by the prime minister of India which has to recommend the names. Any other mechanism devised for filling up these vacancies is redundant," he said.
He had said if the government wanted to advertise these posts to the press and invite applications, even that should have been done much earlier so that all the names could have been received by now and selection made.
Mr Mishra had said if the posts of information commissioners remain vacant, then by the end of the year the number of pending cases with the Commission would mount to over 21,000.
"The right to information would become pointless, if a citizen is to wait to for more than a year to get any information he seeks from the government," Mr Mishra said.
In a separate letter on 20th July, Mr Mishra has questioned the new method of advertising the posts adopted by the government at this stage when such a huge pendency of cases is faced by the panel.
"I understand that new proposals are being mooted now for devising new ways and means for filing up these vacancies and the government has not yet finalised which method to follow... If the government wants to advertise these posts to the Press and invite applications, even that should have been done much earlier so that all the names could have been received by now and selection made," he said.
He said at present most complaints and appeals filed before the Commission come up for disposal nearly after eight to 10 months of filing and if vacancies continued to remain unfilled, the pending cases would mount further.
Mr Mishra has expressed concerns over growing workload on the information commissioners and asked Mr Nair to bring the matter to the prime minister's notice.
RBI governor D Subbarao said it was not possible to say what the RBI had done in the forex market which will be known when the figures were released and would be able to get an idea to the extent or otherwise of intervention
Kolkata: Amidst high volatility in the rupee's exchange rate in respect to the US dollar, the Reserve Bank of India (RBI) on Thursday said the currency's movement is "always on its radar" and the central bank will come out with a definitive statement in this regard in its mid-quarterly meeting on 16th December, reports PTI.
"I cannot say whether we can intervene or not but the exchange rate is always on the radar of RBI," governor D Subbarao told reporters after the central bank's board meet here.
Mr Subbarao said the rupee had depreciated 14% since early August due to inflationary pressures.
"We will be coming out with a more definitive statement in the 16th December review meeting," he added.
"But as of now our understanding of some amount of rupee depreciation and assessment of oil price has been built into the projection of 7% WPI (wholesale price index) inflation by March 2012.
Any revision of this will come out on 16th December," Mr Subbarao said.
He said it was not possible to say what the RBI had done in the forex market which will be known when the figures were released and would be able to get an idea to the extent or otherwise of intervention.
"But as far as rupee depreciation over the last three months is concerned, it had been a result of developments outside the country, particularly Europe," he observed.
"This was because there were no inflows coming in a significant way and the exchange rate has been determined by the current account deficit," he said.
"Three things which we should do to attract more inflows into India, are adjust interest rates for NRI deposits, increase FII limits in sovereign and corporate debt and finally asking the ECB borrowers to bring back money to the country," Mr Subbarao said.
"In order to determine whether to intervene or not, our guide is our policy," he said.
RBI's policy of intervention was to manage volatility or macro-economic instability.
Another factor which would have to be taken into account was on how expectations would be shaped on what RBI did.
On the government's part, efforts would also have to be made to bring more FDI flows into the country.
Asked to comment on criticism from certain quarters that RBI's tight money stance had not been able to contain demand as reflected by high inflation rates, Mr Subbarao said "inflation has resulted from supply shocks and demand pressures.
"Our action had been to contain inflation and there had been criticisms to that," he said. "Supporting growth is our objective as also to maintain price and financial stability."
Regarding food inflation, RBI deputy governor Subir Gokarm said that food prices were responding due to two good monsoons in a row and improvement in supply situation.
"We need long-term supply responses to moderate food inflation on a more sustained basis," he added.


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Whitewalls was the castle of House Butterwell in the eastern riverlands. It was built near the Gods Eye[1] and was closer to Maidenpool than to King's Landing.[2]
Built forty years before the Second Blackfyre Rebellion, about 171 AC, by Lord Butterwell, who had been Hand of the King to Aegon IV Targaryen, Whitewalls was commonly called the Milkhouse by those who lived near it. Its walls and towers where made of white stone that had been quarried in the Vale. Its floors and pillars were crafted from white marble veined with gold. The rafters were carved from the trunks of weirwoods. It had been costly to build.[2] Some seventy to eighty years before the War of the Five Kings, one could take a ferry across the Trident from the crossroads inn to the road that led to Lord Harroway's Town and Whitewalls. However, the river moved and the ferry landing at the inn was abandoned.[3]
Whitewalls was the site of the Whitewalls tourney and the Second Blackfyre Rebellion in 211 AC. Lord Ambrose Butterwell had to forfeit it to the Iron Throne for the part he played in the rebellion. Lord Bloodraven decided to have it pulled apart stone by stone and the earth salted.[2]
References and Notes
- ↑ The World of Ice & Fire, The Targaryen Kings: Aerys I.
- ↑ 2.0 2.1 2.2 The Mystery Knight.
- ↑ A Feast for Crows, Chapter 37, Brienne VII.


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conformitynoun [ U ]uk /kənˈfɔː.mə.ti/ us /kənˈfɔːr.mə.t̬i/
› behaviour that follows the usual standards that are expected by a group or society:
It's depressing how much conformity there is in such young children.
› also conformance the process of a product being made as it was designed, without mistakes or faults:
Our goal is to improve conformity with customer requirements.
conformity to specification
Thesaurus: synonyms and related words
Custom, tradition & conformity
You can also find related words, phrases, and synonyms in the topics:


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Notice - This site contains archived material
- Status: The IRIS Assessment for the pesticide Dimethipin has been archived and is not being reassessed by IRIS at this time.
- Archived IRIS Summary (PDF) (12 pp, 110 K)
- Archive Disclaimer: The IRIS Program has archived a number of IRIS entries for pesticides that have been assessed more recently by EPA's Pesticide Program. The IRIS program announced in 2004 that chemicals that are solely used as pesticides would not be re-assessed.
Information from EPA's Pesticide Program
- Human Health Benchmarks for Pesticides (HHBP) information for Dimethipin. The HHBP website provides toxicity reference values for a number of pesticides to help determine if there is a potential health risk when pesticides are detected in water. However, the toxicity information from the HHBP table may be useful for other purposes.
- Additional information from EPA's Pesticide Program for Dimethipin.
- Contact us about pesticides
Health Hazard Assessments for Effects Other than Cancer
This data is archived and for historical reference only. Please refer to the Pesticide Program Toxicity Value.
Reference Dose for Oral Exposure (RfD) (PDF) (12 pp, 110 K)
archived on: 07/15/2016
Reference Concentration for Inhalation Exposure (RfC) (PDF) (12 pp, 110 K)
archived on: 07/15/2016
Not assessed under the IRIS Program.
Cancer Assessment
Weight of Evidence for Cancer (PDF) (12 pp, 110 K)
archived on: 07/15/2016
|WOE Characterization
|Framework for WOE Characterization
|C (Possible human carcinogen)
|Guidelines for Carcinogen Risk Assessment (US EPA, 1986)
- Classification is based on an elevated combined incidence of pulmonary adenomas/carcinomas in male, but not in female, CD-1 mice. A rat study is undergoing further evaluation.
- This may be a synopsis of the full weight-of-evidence narrative.
Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (12 pp, 110 K)
Not assessed under the IRIS Program.
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Not assessed under the IRIS Program.
You will need Adobe Reader to view some of the files on this page. See EPA's PDF page to learn more.


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(Nov. 18, 2009)--During the holiday season, the Institute of Texan Cultures will present two Pribyl family vintage nativity scenes, a 15-foot Christmas tree under the dome, the "Winter Scenes of Texas" photo exhibit, a Dec. 5 family day with holiday storytelling and the Alamo City Men's Chorale, and the first edition of an Institute of Texan Cultures holiday ornament. (See the institute's holiday hours schedule below.)
Two Pribyl family vintage nativity scenes will be on display through Jan. 3. Painted in the 1890s, the dioramas measure between eight and 18 feet long. They feature the Bethlehem stable against a backdrop of an Austrian village with several characters painted in meticulous detail.
A 15-foot English Fir Christmas tree will be under the dome featuring 4,550 star-shaped LED lights and hundreds of ornaments, and the entrance to the main exhibit floor will be livened with a seasonal "Winter Scenes of Texas" photo exhibit. The display features more than 30 historic photos from the institute's archives. Reaching back to the 1890s and through the 1980s, the exhibit showcases snowscapes from San Antonio, Fredericksburg, Granger, Corpus Christi, Victoria, Floresville and other Texas towns. Smaller versions of the photographs are for sale at the museum store.
For the first time, the institute will issue its own holiday ornament. A three-dimensional miniature diorama, the ornament shows the iconic flagpole plaza with flags painted in enamel. The bridge over the Confluence Fountain leads back to the distinct inverted pyramid of the institute's main building. A garland of green and red enamel holly leaves and berries frames the scene with "Institute of Texan Cultures" on the top scroll and "San Antonio, Texas" at the bottom. The ornament can be purchased at the museum store for $18.95 and will be in stock Dec. 4. Additionally, the museum store sells a selection of Texas keepsakes, books and handmade and fair-trade gifts.
On Dec. 5, the institute will host "Family Holiday Celebration" featuring performances by the Alamo City Men's Chorale, storytelling of holiday season tales and traditions, and children's arts and crafts activities. The celebration will run from 10 a.m. to 4 p.m.
The new year will see several new exhibits including the "Da Dun Fine Arts Festival of Taichung City," Jan. 16-Feb. 28, a cultural exchange showcasing the best artworks of China and Taiwan including sculpture, digital art, photography, water color painting and more; and "Race: Are We So Different?" Jan. 23-May 16, which explores the science, history and everyday impact of race perceptions.
The Institute of Texan Cultures is on the UTSA HemisFair Park Campus, 801 E. Durango Blvd., a short distance from the Alamo and the River Walk. Admission is $8 for adults (ages 12-64); $7 for seniors (ages 65+); $6 for children (ages 3-11); free with membership, UTSA or Alamo Colleges identification.
The 182,000-square-foot complex features 65,000 square feet of interactive exhibits and displays that tell the stories of Texans. The institute also develops resources for educators and lifelong learners on topics of cultural heritage. For more information, call 210-458-2300 or visit the Institute of Texan Cultures Web site.
Institute of Texan Cultures holiday hours
Nov. 26, Thanksgiving Day -- closed
Nov. 27, day after Thanksgiving -- 10 a.m.-5 p.m.
Dec. 5, Family Day -- 10 a.m.-5 p.m. (activities end at 4 p.m.)
Dec. 24, Christmas Eve -- 10 a.m.-3 p.m.
Dec. 25, Christmas Day -- closed
Dec. 26-30 -- 10 a.m.-5 p.m.
Dec. 30, New Year's Eve -- 10 a.m.-3 p.m.
Jan. 1, New Year's Day -- closed
Orientation marks a major step toward becoming a Roadrunner. It is a unique experience designed to welcome freshmen and transfers to UTSA and ensure a successful transition into college. They will learn about UTSA, prepare for their first semester and have fun meeting other students. There is also a special Family Orientation program too.
Various locations, Main and Downtown Campuses
Come out and meet Dr. Ray Bateman, ARL South Cyber on-site Lead, and Kristin Schweitzer who form the nucleus of ARL South Cyber on our campus. They will give a brief overview of the Army Research Laboratory (ARL) and how it fits within the Army's hierarchy. Morning session is 11 a.m. to 12 p.m. Afternoon session is 2 p.m. to 3 p.m.
John Peace Library (JPL 4.04.12C), Main Campus
The sympoisum will focus on the interface between aging and neurodegenerative diseases, will educate the wider research community about advancements in this fast-paced field and stimulate collaborative research in this area. Register online for this free event.
H-E-B University Center Ballroom (HUC 1.106), Main Campus
The 23rd International Conference on Historical Linguistics is offering four special panels open and free to the San Antonio public July 31-Aug. 3 to mark the tricentennial next year. The event is co-sponsored by UTSA Research.
Hotel Contessa, 306 W. Market St., San Antonio
Get ready for the fall 2017 semester at UTSA with a variety of fun and informational events.
Various locations, Main and Downtown Campuses
Other Calendars
» UTSA Events | » Academic | » Institute of Texan Cultures
The University of Texas at San Antonio is dedicated to the advancement of knowledge through research and discovery, teaching and learning, community engagement and public service. As an institution of access and excellence, UTSA embraces multicultural traditions and serves as a center for intellectual and creative resources as well as a catalyst for socioeconomic development and the commercialization of intellectual property - for Texas, the nation and the world.
To be a premier public research university, providing access to educational excellence and preparing citizen leaders for the global environment.
We encourage an environment of dialogue and discovery, where integrity, excellence, inclusiveness, respect, collaboration and innovation are fostered.


text: Hello. My name is Arsalan. I am 25 years old. I am an Elecrtrical engineer, currently doing my masters from Hochshule Rheinwaal Germany. I have already given English lessons to students in Pakistan. I am very enthusiastic and I am a very friendly person. If you are my student then you don't have to worry about your grades.


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"Significant Immigrant Populations from Central America" Fueling Violent Gang MS-13
A major bust involving the nation's most violent street gang reveals that the criminal enterprise—known as Mara Salvatrucha or MS-13—continues to be energized with new recruits provided by the steady flow of illegal immigrant minors entering the U.S. through Mexico. The affiliation between gangs and the hordes of Central American…
DHS Celebrates: Only 527,127 Overstay Visa, Thousands from Terrorist Nations
Nearly 15 years after the worst terrorist attack in U.S. history, the government admits that more than half a million foreigners with expired visas—like the 9/11 jihadists—remain in the country and thousands are from terrorist nations like Pakistan, Iraq, Yemen, Libya and Syria. Even more disturbing is that the Obama…
Judicial Watch Uncovers New State Department Records Confirming Arab Smuggling "Cells," Al Qaeda Leader in Mexico.
For more than a decade the U.S. government has known that "Arab extremists" are entering the country through Mexico with the assistance of smuggling network "cells," according to State Department documents obtained by Judicial Watch that reveal among them was a top Al Qaeda operative wanted by the FBI. Some…
Iraqi Refugee Granted U.S. Residency Charged with Terrorism in Texas
As the Obama administration welcomes throngs of "displaced" nationals from terrorist countries, an Iraqi refugee granted residency after coming to the U.S. as a teenager has been charged with supporting the jihadist group Islamic State of Iraq and the Levant (ISIL). The once-displaced refugee, Omar Faraj Saeed Al Hardan, is…
U.S Gives Immigrants "Severe Weather" Amnesty for Recent Floods
Always on the prowl for opportunities to grant illegal immigrants reprieve, the Obama administration is capitalizing on the recent floods to reward undocumented aliens in the affected regions with a special "severe weather immigration relief." The measure was recently announced by the Department of Homeland Security (DHS) agency—U.S. Citizenship and…
Surge in Illegal Aliens, 500% Increase in Some U.S. Ports of Entry
Hordes of Central Americans continue infiltrating the United States through the Mexican border with three ports of entry seeing a mind-boggling 500% increase in illegal immigrants during the first months of fiscal year 2016 compared to the same period in 2015, according to government records. The Boquillas, El Paso, Texas…
Judicial Watch: Secret Service Expenses for Obama's 2013 Hawaii Christmas Vacation Cost Taxpayers $316,698.03, Taxpayers Paid Over $8 Million for 17-Day Vacation
(Washington, DC) – Judicial Watch announced today that it recently received expense records from the Department of Homeland Security revealing that Secret Service expenses for the Obama family vacation to Honolulu during December 2013-January 2014 cost taxpayers at least $316,698.03. These new expenses bring the total for the Hawaii Christmas…
Somali Charged in Terrorism Ring Worked at Major U.S. Airport
In the latest disturbing example of the government's failure to root out foreign Islamic terrorists a young Somali man, who bragged about building rockets that could strike landing planes, worked at a major U.S. airport as a baggage handler. This month the Somali, 20-year-old Abdirizak Mohamed Warsame, was charged with…
Overall Deportations Drop in 2015, 27% for Criminal Aliens
A year after freeing tens of thousands of illegal immigrants convicted of serious crimes, the Department of Homeland Security (DHS) is distorting annual deportation figures by falsely claiming the number of criminal aliens removed from the U.S. keeps increasing when in fact it's shrinking drastically. In fiscal year 2015 deportation…
FBI Sued for Civil Rights Violations for Surveilling Muslims Near San Bernardino
With the region—and the entire nation—still reeling from the San Bernardino terrorist attacks, a federal appellate court is considering whether the Federal Bureau of Investigation (FBI) should be punished for surveilling Muslims in a nearby southern California county. The case centers around a federal surveillance program that focused on the…
DHS Sec. Protecting Muslims from McCarthyism his Communist Grandpa Lived Under
The Secretary of Homeland Security is the second high-ranking Obama administration official with a relative investigated for Communism by the U.S. government, Judicial Watch has confirmed. This is relevant because, although Islamic terrorists keep attacking America, the cabinet official responsible for the nation's safety has vowed to protect Muslims from…
Team led by Middle Eastern Woman Caught Surveilling U.S. Facility on Mexican Border
A Middle Eastern woman was caught surveilling a U.S. port of entry on the Mexican border holding a sketchbook with Arabic writing and drawings of the facility and its security system, federal law enforcement sources tell Judicial Watch. The woman has been identified as 23-year-old Leila Abdelrazaq, according to a…
DHS Rarely Deports for Terrorism: 1,000th of 1 % of Cases
It appears that Islamic extremists are infiltrating the United States in growing numbers yet government figures show that foreigners are hardly ever removed from the country on terrorism grounds. This is not surprising considering the Obama administration regularly shields criminal illegal immigrants with extensive rap sheets from deportation. Why not…
ODNI Confirms Terrorists Tried to Enter U.S. as Syrian Refugees
Individuals with ties to terrorist groups in Syria have tried to infiltrate the United States through the Obama refugee program that will admit at least 10,000 Syrians, the Office of the Director of National Intelligence (ODNI) has confirmed. The disturbing admission comes amid robust assurances by the administration that the…
Judicial Watch Files Taxpayer Lawsuit against San Francisco Sanctuary Ordinance Expansion
(Washington, DC) – Judicial Watch announced today that it filed a taxpayer lawsuit in San Francisco County, California Superior Court to end a March 2015 expansion of San Francisco's sanctuary ordinance that prohibits San Francisco Sheriff's Department personnel from exchanging information with Immigration and Customs Enforcement (ICE) about the
JW Supreme Court Victory
Judicial Watch Scores Supreme Court Win Benghazi Scandal Exposed: Hillary Clinton Slept Past Staff Efforts to Set Up Intelligence Briefing Another Email Scandal – At Department of Homeland Security Judicial Watch Scores Supreme Court Win How about a little good news? Your Judicial Watch, on behalf of a group of…
Middle Eastern Men Arrested Near Mexican Border with Steel Cylinders
Five young Middle Eastern men were apprehended by the U.S. Border Patrol this week in an Arizona town situated about 30 miles from the Mexican border, law enforcement and other sources told Judicial Watch. Border Patrol agents spotted the men crossing a ranch property in the vicinity of Amado, which…
ISIS Czar a Terrorist Sympathizer Once Fired by Obama for Hamas Ties
A radical foreign policy adviser fired by President Obama years ago for meeting with the Palestinian terrorist group Hamas is back as the administration's new czar in charge of countering the Islamic State of Iraq and Greater Syria (ISIS). The White House downplayed the new appointment by burying it deep…
U.S. Gets Work Discrimination Victims Record $525 Mil in Settlements
Key government agencies—including the Department of Homeland Security—are notorious for perpetual lapses but at least one, the Obama administration's discrimination police, is earning accolades for going beyond the call of duty even shattering performance records. It's part of the president's mission to eradicate discrimination in America's workforce, especially
DHS: Inept $1 Billion Bioterror System Is All We Have
After squandering a billion dollars—87 million in the last year alone—on a useless system to detect biological attacks, the Department of Homeland Security (DHS) insists on wasting more money on the flawed program because the government has no back up plan to deal with bioterrorism. It's only taken 12 years…


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Radotinib approved in South Korea for CML
The Yonhap
The Yonhap
The patient advocacy session at the recent 16th Congress of the European Hematology Association in London focused on adherence to cancer treatments, and was filled to capacity, with the many attendees having to watch it from an overflow area.
Dr David Marin, Reader in Onco-Haematology at Imperial College, London presented research published last year in the Journal of Clinical Oncology that dramatically demonstrated how adherence to chronic myeloid leukemia (CML) therapy is the critical factor for achieving molecular responses.
In a study of 87 CML patients taking imatinib (Glivec®/Gleevec®) for a median period of 91 days, Dr Marin showed that no major molecular response (MMR) was observed when adherence was ≤ 80% and no complete molecular responses (CMR) were observed when adherence was ≤ 90%. The graphical figure that he presented from his paper, dramatically shows how missing only a few doses of drug can have a major impact on outcome:
Although the work by Marin and colleagues at the Hammersmith Hospital was undertaken with CML patients taking imatinib, the paper notes that adherence problems
"may apply equally to patients receiving second-generation tyrosine kinase inhibitors."
Imatinib is the only TKI approved in the UK, thus that's the only one available for studies there to date.
What made this data so compelling was the study rationale that used an electronic pill container, the medical event monitoring system (MEMS™) from the Aardex Group. This product contains a microchip that records the date and time it is opened.
Dr Marin's study showed that "lack of adherence is underestimated by conventional methods." Self-reporting of adherence and pill counts are inaccurate compared to electronic data capture using MEMS (study subjects were unaware of the micro-chip in the pill bottle).
When psychologists at the Hammersmith Hospital subsequently interviewed patients who missed doses of drug, they found intentional and non-intentional adherence reasons.
A few excepts of patient quotes from Dr Marin's presentation:
Intentional non-adherence:
"Oh I can't be bothered tonight, it's not going to kill me [to miss a dose]"
"I thought there was no way I was going [on holiday] and being tired."
Unintentional non-adherence:
"And sometimes you just forget"
"[the pharmacy] had no medication for me, so I went for nearly a week with no medication."
Other speakers in the excellent patient advocacy session chaired by Jana Pelouchová (European Cancer Patient Coalition, Czech Republic) and Jan Geissler (CML Advocates Network, Germany) included Giora Sharf (Israeli CML patient's Organization and CML Advocates Network, Israel) and Professor Rudolf Schoberberger (Medical University of Vienna, Austria).
Professor Schoberberger focused on the impact of drug packaging on compliance, particularly in elderly patients, and presented compelling research on how "child-proof" equals "age-proof." Sally Church in her video blog from EHA also discusses the patient advocacy session and how pharma/biotech companies could improve drug packaging.
The issue of adherence is a personal choice that every patient taking a chronic therapy makes. However, as Sally notes on Pharma Strategy Blog more patient and physician education is needed so that patients know there may be dramatic consequences from missing only a few doses per month.
Not only may adherence have a major impact on patient outcome, but as one questioner from France pointed out at the end of the EHA patient advocacy session, "for a statistician it is a nightmare." Poor adherence in clinical trials "means that the true effect of a drug is not well known. Efficacy may be under-estimated if adherence is low."
More monitoring of adherence in clinical trials through the use of MEMS technology may, therefore, be necessary to ensure that clinical trial data shows the true efficacy and adverse event profile of a drug.
I hope that the European Hematology Association (EHA) will make a webcast of this informative patient advocacy session publicly available online as it raised issues of considerable importance to patients, physicians and biotech/pharma companies alike.
Marin, D., Bazeos, A., Mahon, F., Eliasson, L., Milojkovic, D., Bua, M., Apperley, J., Szydlo, R., Desai, R., Kozlowski, K., Paliompeis, C., Latham, V., Foroni, L., Molimard, M., Reid, A., Rezvani, K., de Lavallade, H., Guallar, C., Goldman, J., & Khorashad, J. (2010). Adherence Is the Critical Factor for Achieving Molecular Responses in Patients With Chronic Myeloid Leukemia Who Achieve Complete Cytogenetic Responses on Imatinib Journal of Clinical Oncology, 28 (14), 2381-2388 DOI: 10.1200/JCO.2009.26.3087
The Boston Globe today reported that Blueprint Medicines had received $40M in Series A venture funding.
The VC funding from Third Rock Ventures to the Boston/Cambridge based company is reported to be the largest early-stage funding for a New England life sciences start-up.
Many thanks to @rndubois for his tweets about this that drew it to my attention. You can read more about the financing in Blueprint's press release.
What makes this exciting news? First it adds to the growing reputation of Boston/Cambridge as a hot-spot for cancer research. Blueprint Medicines will be focused on translational medicine and the development of new kinase inhibitors for the treatment of cancer.
Secondly, it confirms what is taught at business school, that investors back management expertise and their belief in the entrepreneurs ability to execute. In the case of Blueprint Medicines the scientific co-founders are Dr Nicholas Lyndon and Dr Brian Druker, who were instrumental in the development of imatinib (Gleevec/Glivec), a tyrosine kinase inhibitor that revolutionized the treatment of chronic myeloid leukemia (CML).
Blueprint Medicines is a company to watch for the future and Biotech Strategy Blog wishes it well in the quest for personalized medicine and more effective cancer treatments.
The launch of the company in Boston/Cambridge adds to my view that Boston is emerging as the premier biotech region on the East Coast for start-ups interested in oncology and translational medicine.