text:
Plumes of neuronal activity propagate in three dimensions through the nuclear avian brain
In mammals, the slow-oscillations of neuronal membrane potentials (reflected in the electroencephalogram as high-amplitude, slow-waves), which occur during non-rapid eye movement sleep and anesthesia, propagate across the neocortex largely as two-dimensional traveling waves. However, it remains unknown if the traveling nature of slow-waves is unique to the laminar cytoarchitecture and associated computational properties of the neocortex.
We demonstrate that local field potential slow-waves and correlated multiunit activity propagate as complex three-dimensional plumes of neuronal activity through the avian brain, owing to its non-laminar, nuclear neuronal cytoarchitecture.
The traveling nature of slow-waves is not dependent upon the laminar organization of the neocortex, and is unlikely to subserve functions unique to this pattern of neuronal organization. Finally, the three-dimensional geometry of propagating plumes may reflect computational properties not found in mammals that contributed to the evolution of nuclear neuronal organization and complex cognition in birds.
Historically, the mammalian neocortex has been viewed as the pinnacle of brain evolution. The highly structured six-layered laminar cytoarchitecture of the neocortex and the associated computational properties contributing to complex cognition added to this view. However, exactly how laminar cytoarchitecture and associated neurophysiological processes mediate complex cognition remains poorly understood. Our understanding of how the neocortex works can be informed by comparisons with other animals. Notably, comparisons with non-mammalian groups lacking laminar cytoarchitecture, as is the case in birds, can be used to isolate traits that depend upon laminar cytoarchitecture from those that do not. In this study, we use this comparative approach to gain insight into the neocortex by examining sleep-related neuronal activity in the avian brain.
A growing body of research suggests that the brain rhythms occurring during sleep are involved in processing information acquired during wakefulness
To distinguish between these alternatives, we studied brain activity in birds, the only non-mammalian group known to exhibit slow-oscillations
We recorded intracerebral potentials in the zebra finch (
Results and discussion
Analogue multiunit activity (AMUA) and LFP were recorded using a 64-channel silicon multi-electrode probe inserted into the hyperpallium (Figure
Figure 1
High-density recording methods
High-density recording methods. (A) Location of the 64-channel silicon multi-electrode probe. An 8 × 8 electrode grid with 200 μm inter-site spacing extends over a 1,400 × 1,400 μm plane in the hyperpallium. Probes were inserted horizontally (red plane) or sagitally (yellow plane). The horizontal plane is orthogonal to the sagittal plane and is shown as a thin line in the sagittal brain section. The orientation of horizontal electrode grids is always depicted so that the medial side is on the left and the anterior side (that is, brain surface) is on top; sagittal grids are depicted so that the caudal side is on the left and the anterior side (that is, brain surface) is on top. Together, horizontal and sagittal recordings provide insight into the three-dimensional spatial extent of activity propagation patterns. Thalamic input to the hyperpallium (H), which is where most recordings were performed (
Figure 2
Propagating slow-waves in the zebra finch forebrain
Propagating slow-waves in the zebra finch forebrain. (A) This is an expanded five-second recording showing the temporal pattern of local field potential (LFP) and analogue multiunit activity (AMUA) (Bird 6, horizontal plane, and electrode site column 6, row 4 from Figure
At a time scale of seconds, LFP patterns appear visually similar between most electrode sites (Figure
Additional file 1: Figure S1
Electrode sites with positive local field potential (LFP) peaks near the brain surface are not usually associated with strong analogue multiunit activity (AMUA) peaks in the same recording site, suggesting the absence of neurons with action potential firing at these sites. To quantitatively verify this observation we calculated for every site (
Click here for file
At shorter time-scales of tens to hundreds of milliseconds, however, single oscillations do not appear as near-synchronous and globally distributed. For example, Figure
Additional file 2: Video S1
Video of the image sequence shown in Figure
Click here for file
Additional file 3: Video S2
Video of the image sequence shown in Figure
Click here for file
Additional file 4: Video S3
Video of the image sequence shown in Figure
Click here for file
Additional file 5: Video S4
Video of the image sequence shown in Figure
Click here for file
Additional file 6: Video S5
Video of the image sequence shown in Figure
Click here for file
Additional file 7: Video S6
Longer example of temporospatial slow-wave patterns in Bird 5. The multi-electrode probe is situated in a horizontal plane in the hyperpallium (cf. Figure
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Additional file 8: Video S7
Longer example of temporospatial slow-wave patterns in Bird 9. The multi-electrode probe is situated in a horizontal plane in the hyperpallium (cf. Figure
Click here for file
Additional file 9: Video S8
Longer example of temporospatial slow-wave patterns in Bird 1. The multi-electrode probe is situated in a sagittal plane in the hyperpallium (cf. Figure
Click here for file
Additional file 10: Video S9
Longer example of temporospatial slow-wave patterns in Bird 12. The multi-electrode probe is situated in a horizontal plane in caudolateral nidopallium (NCL), a forebrain region that is almost maximally distant from the hyperpallium.
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We compiled videos from all of our recordings from the hyperpallium (
Figure 3
Examples of propagating plumes
Examples of propagating plumes. (A) A plume in the hyperpallium of Bird 5 that sweeps across the grid in a similar direction as the plume in Figure
Additional file 11: Figure S2
Distribution of the translation speed of local field potential (LFP) plumes centers across the 2-D electrode gird in Bird 5 (horizontal hyperpallial recording). Across birds, the mean speed ranged from 0.023 to 0.040 m/s (mean +/− SEM: 0.031+/− 0.002,
Click here for file
Although we focus on the hyperpallium in the current study, we wondered whether propagating plume activity occurs outside the hyperpallium. To address this question, we added two recordings (
Despite the large variability in propagation patterns that we observed in the videos of all recordings (the Additional file
First, to identify systematic time delays in AMUA activity between each electrode site and all other electrode sites, we calculated the maxima of normalized cross-correlation functions for each identified plume in every recording. Illustrating this process for the propagating plume shown in Figure
Figure 4
Directional structure in action potential propagation
Directional structure in action potential propagation. Time lags of maximum between-electrode site cross-correlation of analogue multiunit activity (AMUA) signals show that despite the diversity of patterns in action potential activity propagation visible in the recording videos, there is directional structure in action potential plume propagation patterns. (A) This is an example of mean between-electrode time lags in the recording of Bird 5 (horizontal recording in the hyperpallium, H). Means are calculated over identified plumes (
Because they are based on normalized cross-correlation functions, lag maps of AMUA plumes capture differences in the timing of oscillation events across the electrode grid, but not their magnitudes. In a second analysis approach we therefore aimed to capture overall propagation directions of predominant concentrations of neural activity based on LFP. LFP fields are less localized than are action potential fields and, therefore, better reflect the magnitude of neural activity in our recordings. We identified, at 1-ms intervals, plumes of LFP in the electrode grid that were stronger (that is, more negative) than a threshold criterion of −250 mV, and tracked the changes of their spatial mean in time (see example, Figure
Figure 5
Traveling LFP plume trajectories
Traveling LFP plume trajectories. LFP plume mean location was determined in 1-ms time steps (see Experimental Procedures and Figure
Our experimental animals were anesthetized, not sleeping spontaneously. In mammals, some kinds of anesthesia, including isoflurane, activate normal sleep promoting regions in the hypothalamus
Additional file 12: Figure S3
Mean spectral power density of the local field potential (LFP) signals recorded in the hyperpallium shows a peak at 0.45 Hz. The mean (+/− SEM) was calculated over the power spectra from all hyperpallium recordings (
Click here for file
As in the laminar mammalian neocortex, slow-waves propagate through the nuclear avian brain. Thus, an important insight from our findings is that the propagating nature of slow-waves during NREM sleep and anesthesia does not reflect a neural phenomenon that is unique to mammals, or that depends upon uniquely mammalian cortical cytoarchitecture or computational properties. Rather, propagating slow-waves reflect a more general type of sleep-related neural activity. Propagating slow-waves may have evolved independently in birds and mammals, perhaps for functional reasons, despite their differing cortical cytoarchitectures, or it may represent an ancestral trait. Although visually evoked propagating two-dimensional waves have been described in the visual cortex of anesthetized turtles
Although the presence of traveling slow-waves in avian and mammalian brain structures is highly interesting from a comparative viewpoint, and may be linked in terms of function
While the propagating nature of slow-waves is shared by mammals and birds, the geometry of propagation differs between the two. In mammals, although slow-waves may engage different layers of the neocortex at slightly different times
Depending on the actual function of propagating slow-waves, the three-dimensional nature of plumes in the avian brain may have broader implications for understanding the evolution of the nuclear pallial structures subserving complex cognition in birds. While the propagating nature of slow-waves in general may simply be an epiphenomenon of excitable interconnected neurons
Finally, our findings may have implications for the interpretation of sleep-related neuronal activity in the song system of sleeping zebra finches, a prominent model for investigating sleep's role in memory consolidation
We demonstrate that slow-waves propagate as complex three-dimensional plumes of neuronal activity in the nuclear avian brain. These findings indicate that the propagating nature of slow-waves during NREM sleep and anesthesia does not reflect a neural phenomenon that is unique to mammals, or that depends upon uniquely mammalian cortical cytoarchitecture or computational properties. As such, efforts to understand the mechanisms responsible for propagating waves should not focus on lamination,
Thirteen adult (>90-day-old) female zebra finches were used in this study. The birds were reared in a colony and housed in an aviary with other adult zebra finches. All procedures were performed under systemic anesthesia under supervision of the institutional
After the birds were anesthetized with isoflurane vaporized in oxygen (induction, 3%; maintenance, 1.0 to 1.25%), meloxicam (0.3 mg/kg; intramuscular injection) was administered for systemic analgesia. The head was fixed in a stereotaxic frame while the body rested on a heating pad to maintain body temperature. The angle of the head was 0 to 20º, except for one bird (Bird 13, caudomedial nidopallium, NCM) where it was 45º. After 20 minutes, the skull was exposed and a rectangular craniotomy was performed overlying the multi-electrode probe insertion point. An incision was made in the dura to allow for insertion of the probe. In most birds (
To record neural activity, we used 64-channel silicon-based multi-electrode probes (NeuroNexus Technologies, Ann Arbor, MI, USA; a8 × 8 to 5 mm 200-200-413). These had eight parallel shanks (thickness: 15 μm, inter-shank spacing, 200 μm), each with eight iridium electrode sites (site surface, 413 μm2; inter-site spacing 200 μm), so that the 8 × 8 square matrix of electrode sites extended over an area 1,400 × 1,400 μm.
Initially, the tips of the probe shanks were positioned just above the brain surface to verify visually (magnification 60×) that the head was fixed well and did not move due to breathing or the heartbeat. The probe was then lowered in small steps to a position where the deepest shank reached its recording depth. In the hyperpallium, this was a depth of between 1,470 μm and 1,700 μm below the brain surface. This way, most electrode sites were situated in the hyperpallial nuclei (primarily the hyperpallium apicale, the most dorsal and thick nucleus), with the top-most sites just beneath the brain surface, while some of the deepest electrode sites were situated in the underlying mesopallium (Figure
Recorded signals were referenced to a silver wire under the scalp over the cerebellum and buffered by headstage preamplifiers (10× gain; MPA32I; MultiChannel Systems, Reutlingen, Germany) before amplification with a multichannel amplifier (250× gain; bandpass filters 0.1 to 5,000 Hz; PGA64; MultiChannel Systems, Austin, TX, USA). The amplified and filtered signals were digitized with a sampling frequency of 14 kHz and 16-bit resolution (NI9205; National Instruments), and stored on disk in HDF5 files
At the end of the recording session, birds were sacrificed by increasing the level of isoflurane to 5%, after which the brain was removed and frozen for histology to determine electrode site placements
Data analyses
Analyses were performed using the scientific computing package SciPy, version 0.10
Correlation coefficients reported in the text were calculated using decimated (sampling rate 1.4 kHz) and normalized signals, and were based on full recordings. The correlation coefficient between two signals was defined as the absolute value of their cross-correlation function at
AMUA plume propagation analyses (Figure
Temporospatial propagation of LFP plumes across the 8 × 8 recording electrode matrix was quantified using a different methodology (for example, Figure
Before implantation, the multi-electrode probes were coated with the fluorescent dye DiI for anatomical registration with histological sections. Frozen brains were cut into 25 μm sections using a freezing microtome and mounted on glass slides. Sections were fixed in 4% formaldehyde solution in phosphate-buffered saline, and then DAPI-stained. Fluorescence microscopy was used to verify probe location in 11 of 13 birds.
Supplementary videos were rendered by low-pass filtering LFP and AMUA signals at 100 Hz and decimating them in the time domain with factors 560 (for real-time speed), 56 (for 0.1× speed), or 22 (for 0.04× speed) to obtain video-compatible sampling rates of 25 Hz.
AMUA: Analogue multiunit activity; EEG: Eectroencephalogram; LFP: Local field potential; NC: Caudal nidopallium; NCL: Caudolateral nidopallium; NCM: Caudomedial nidopallium; NREM: Non-rapid eye movement.
Competing interests
The authors declare no competing financial interests.
Author' contributions
GJLB, JAL, and NCR designed the study. GJLB and JvdM collected the data. GJLB and NCR analyzed the data and wrote the paper. All authors read and approved the final manuscript.
This study was supported by the Max Planck Society and by a Marie Curie Intra European Fellowship within the 7th European Community Framework Programme to GJLB We thank Manfred Gahr for providing laboratory facilities and equipment.
The memory function of sleep
Grouping of brain rhythms in corticothalamic systems
Slow waves, synaptic plasticity and information processing: insights from transcranial magnetic stimulation and high-density EEG experiments
Sleep oscillations in the thalamocortical system induce long-term neuronal plasticity
The sleep slow oscillation as a traveling wave
Cortical firing and sleep homeostasis
Regional slow waves and spindles in human sleep
Making waves: initiation and propagation of corticothalamic Ca2+ waves
Source modeling sleep slow waves
Mirrored bilateral slow-wave cortical activity within local circuits revealed by fast bihemispheric voltage-sensitive dye imaging in anesthetized and awake mice
Properties of slow oscillation during slow-wave sleep and anesthesia in cats
Complex propagation patterns characterize human cortical activity during slow-wave sleep
Long-range correlation of the membrane potential in neocortical neurons during slow oscillation
Consistent sequential activity across diverse forms of UP states under ketamine anesthesia
Spontaneous cortical activity alternates between motifs defined by regional axonal projections
Traveling electrical waves in cortex: insights from phase dynamics and speculation on a computational role
Spike timing–dependent plasticity: a Hebbian learning rule
Columnar interactions determine horizontal propagation of recurrent network activity in neocortex
Physiology and morphology of intratelencephalically projecting corticostriatal-type neurons in pigeons as revealed by intracellular recording and cell filling
Local sleep homeostasis in the avian brain: convergence of sleep function in mammals and birds?
Avian sleep
Laminar and columnar auditory cortex in avian brain
Optical imaging of retinotopic maps in a small songbird, the zebra finch
Do birds possess homologues of mammalian primary visual, somatosensory and motor cortices?
Cytoarchitecture and visual receptive neurons in the Wulst of the Japanese quail (
Insight without cortex: lessons from the avian brain
Neural processing of short-term recurrence in songbird vocal communication
Large-scale synchronized activity during vocal deviance detection in the zebra finch auditory forebrain
Direct activation of sleep-promoting VLPO neurons by volatile anesthetics contributes to anesthetic hypnosis
A sleep/wake circuit controls isoflurane sensitivity in Drosophila
Differences between ipsilaterally and contralaterally evoked potentials in the visual wulst of the zebra finch
EEG: origin and measurement
Mammalian-like features of sleep structure in zebra finches
Spatiotemporal analysis of local field potentials and unit discharges in cat cerebral cortex during natural wake and sleep states
Avalanche analysis from multielectrode ensemble recordings in cat, monkey, and human cerebral cortex during wakefulness and sleep
Digital atlas of the zebra finch (
Effects of anesthesia on the response to sleep deprivation
Direct evidence for local oscillatory current sources and intracortical phase gradients in turtle visual cortex
Response to commentary on evolution of slow-wave sleep and palliopallial connectivity in mammals and birds: a hypothesis
Laminar structure of spontaneous and sensory-evoked population activity in auditory cortex
Origin of active states in local neocortical networks during slow sleep oscillation
Propagating waves of activity in the neocortex: what they are, what they do
Sleep and the single neuron: the role of global slow oscillations in individual cell rest
Propagating waves mediate information transfer in the motor cortex
Sleep and sensorimotor integration during early vocal learning in a songbird
Song replay during sleep and computational rules for sensorimotor vocal learning
Activity in a premotor cortical nucleus of zebra finches is locally organized and exhibits auditory selectivity in neurons but not in glia
Sleep-related spike bursts in HVC are driven by the nucleus interface of the nidopallium
Sleep-related neural activity in a premotor and a basal-ganglia pathway of the songbird
A dynamic deep sleep stage in Drosophila
Hierarchical data format version 5, 2000–2014
SciPy: open source scientific tools for python


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"Education was her life, and she loved every minute of it"
"Olson's Pajama Project" will honor Sharon Olson's vision! Beginning November 3 and throughout the month of November all 17 Loveland, Colorado elementary schools are teaming up to collect gently-used and new children's pajamas. The pajamas will be given to Loveland elementary-aged children who otherwise would not have any for the winter season. The Olson Pajama Project will be an annual event to honor former Thompson School Board President and teacher, Sharon Olson, who passed away in February, 2014.
The Olson Pajama Project, headed up by David Irby of The Groves Agency and Kendra Vair Educator Effectiveness Coach for the Thompson School District, both former students of Olson, who feel that this project has been a long time coming.
"It was a few years back when Sharon and I sat down to catch up over coffee," said Irby. "We hadn't seen each other in years but I could tell right away she had an assignment for me."
Olson's excitement about this new project wasn't lost on Irby. "She said, 'I have this idea. It's all about pajamas,'" recalls Irby. "Sharon went on to explain that there is poverty in Loveland and a large number of kids in our town don't have pajamas."
When Irby asked Olson what these kids slept in, she simply said, "Their jeans."
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Now, in honor of Olson and the love she had for the children of this town, Irby, Vair and their volunteers, supporters and donors are helping to make Olson's vision a reality. "We're going to succeed beyond her wildest dreams. She'll be proud," said Irby. "This is going to be a fun project."
Donation boxes will be located in the office of every Loveland elementary school, and the project requests that donated pajamas be in sizes suited for elementary-age children. The school that collects the most wearable pajamas will be the first to receive the traveling Olson Trophy.
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For further information, please contact David Irby at 970-203-5561 (call or text) or at firstname.lastname@example.com
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text: Jax Pavan 386,693,780 was one of the 582,797,754 Human males named Jax Pavan on Coruscant. He lived in colonial Coruscant where he worked as a wigmaker. The tallest wig he ever made was a whopping four feet, designed for one of Count Dooku's lady friends. There are rumors that he made a wig for Queen Amidala, but this is complete speculation. Palpatine also was one of Jax Pavan 386,693,780's supposed customers, but he didn't have one, he just needed one. That and an entirely different face.


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For his latest book, So You've Been Publicly Shamed, Jon Ronson spent three years traveling the world and talking to people who'd been subjected to high-profile public shamings. Whatever their transgression, the response was to be faced by an angry mob, as Ronson calls them "collective outrage circles" devoted to tearing down said person from any position of power. It does not, Ronson suggests gently, reflect so well on society as a whole.
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http://www.elodiscovery.com/ DISCOVERY - Welcome to the show. Jeff Lynne & ELO website.
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Livin' Thing What an awesome song this is, ELO really do know to make good stuff. This is such a great song that it has over 1 million plays now...shows how ...


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Minae Matsukawa (松川 美苗 Matsukawa Minae) is a video game producer whose works include the Nintendo DS port of Phoenix Wright: Ace Attorney and Apollo Justice: Ace Attorney, as well as Last Ranker for the PlayStation Portable. She also worked as the assistant producer for Disney's Aladdin on the Game Boy Advance.
Matsukawa joined Capcom in 2002. Her previous jobs included working as a debugger for Nintendo and a job as a pet food wholesaler.
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SoMad wrote:I think you are saying that the side effects to getting the flu shot (CDC link)[^] might be hitting me harder because I had some stuff going on before I got it.
Clifford Nelson wrote:Damned background thread
AspDotNetDev wrote:And I can't find any changes made since. There goes my entire morning
Erudite_Eric wrote:1) Liquidise 3 kiwis
Erudite_Eric wrote:Liquidise 3 kiwis...
OriginalGriff wrote:I've managed to convert everything else that was analogue in the house to
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Erudite_Eric wrote:A meat thermometer
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Three New Team Members Join Search Influence
While New Orleans is busy with festival season, Search Influence has hired three new Influencers. We are excited to welcome Rob Monk, Sierra Kellogg, & KD Minor! Robert Monk – Junior Software Developer Born and raised in southern Louisiana, Rob grew up building and taking apart computers and any other …
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Meet Paula Keller French, Director of Sales & Marketing, Search Influence
This blog is part of a series Search Influence is doing in anticipation of International Women's Day on March 8th. We love to tout that 70% of our staff members are women and 66% of our senior management team are women, too. Far above the 20% average seen in the …
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Top 10 Search Influence Blogs of 2016
The year 2016 was filled with memes, the Olympics, superhero movies, and the election. You can bet, with over 46% of people now online worldwide, there were plenty of changes to online marketing, too. If you haven't kept up, here are the top 10 blogs of 2016 to make sure your …
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Top 5 Most Read Search Influence Blogs of October
Between Halloween, the World Series, and Election Season, a few Search Influence blogs may have fallen through the cracks. Don't worry! Here's the top 5 most read blogs from October to get you caught up! #1. The Importance of Content Marketing to Your SEO Strategy Did you know that businesses with …
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A Day in the Life of an Account Manager at Search Influence
With all of the great positions available at Search Influence, it's easy to wonder what each department or each position does every day. Earlier this week, I took to Search Influence's Twitter to break down what my day-to-day as an Account Manager looks like. Though each day is different, they …
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Here Are Our Top 5 Blogs From September
Another month, another top five blogs from Search Influence! All of these posts are chock-full of information that will help you keep your website in tip-top shape and give you some insight into life at Search Influence. Subscribe to our blog to stay up to date on what's going on …
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Happy Working Parents Day: 10 Influencers On Lessons From Their Working Parents
As someone who grew up with working parents, I learned a lot through my parents' experiences. My dad was the "troubleshooter" at the automated and environmental control systems company he worked for. So, his ability to solve problems at work and around the house was something I learned. He always …
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Search Influence Adds 3 New Hires in August
August is traditionally the hottest month in New Orleans each year. This past month, the City and Search Influence were sizzling. Not only were we ranked as one of America's fastest-growing private companies by Inc. magazine (for the 6th straight year I might add), but we also hired three new Influencers to …
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Top 5 Most Read Search Influence Blogs of August
It's back to school time, and you know what that means—time to catch up on your reading! Here are the top five most read Search Influence blog posts of August. Study up! 1: What Happened to Facebook's 20% Text Grid Tool? Ranking in the top five for yet another month, …
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Search Influence Jobs: What Does an Account Associate Do?
I joined the Search Influence team as a Junior Account Associate a little over a year ago. After working closely with my manager and completing the training program, I was then promoted to Account Associate. By that time, I felt like I had learned so much and was excited to …
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If you attended last year's Sundance Film Festival, you might have had the opportunity to glimpse at the future of editing. The radical new technology that was on display was in a small booth, presented by a venture-backed developer of a new kind of human/machine interface, Oblong Industries. The promised glimpse of the future was provided by a conceptual editing interface known as TAMPER. The system is a spatial operating environment, also known as an SOE. What exactly is an SOE? Some of the SOE's core ideas are already familiar to people from the film Minority Report, whose characters performed forensic analysis using massive, gesturally driven displays. Similar depictions of gesturally driven displays have recently shown up in music videos and commercials. The similarity of TAMPER to these fictional depictions is no coincidence. John Underkoffler, chief scientist with Oblong Industries, served as science advisor on Minority Report and based the design of the scenes in the film directly on his earlier work at the MIT Media Lab.
What exactly is TAMPER? Imagine using your hands, instead of a mouse, to move and manipulate video in 3D space in real time. Sounds like science fiction? TAMPER is based on advanced science, but the impressive exhibition of the system at Sundance proved that the technology isn't fiction. In his demonstration, not only does Underkoffler use only his hands to engage transport controls to select clips, rearrange them and edit them, but he also literally grabs specific video elements from precomped scenes from several films, ranging from a 1967 Jacques Tati comedy to a Sergio Leone western and rearranges them on a table in front of him into a real-time video collage where Leone's cowboy shares the mashup with Tati's French vacationer as a car chase from 1971's Vanishing Point tears through the background.
TAMPER runs on Oblong's own proprietary g-speak platform. The SOE is one of the biggest steps forward in the human/computer interface since the keyboard and mouse became the standard method for humans to control computers back in 1984 with the first Mac computers. The g-speak platform on which TAMPER runs is built around free-hand, three-space gestural input. Applications are controlled by hand poses, movement and pointing. Finger and hand motion are tracked to 0.1mm at a 100 Hz scan rate; pointing is pixel-accurate. Gestural input is measurably more efficient than a mouse at performing complex navigation, sorting and selection tasks. The user interacts with the display by pointing instead of touch (or mouse).
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The plastic sheet that forms the base for our garden swing cushions has ripped. Can I buy a replacement sheet to fit the swing? If not, what material and thread would you recommend to make it myself?
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This is taken from a guest post I have written this morning on the Desiring God Blog:One key aspect in how we faithfully pursue fruitfulness is what we are hoping for. After last week's post on Spurgeon, I was asked by someone which of his books I would recommend to begin with if they've never read him before. I am tempted to just say, Any of them! But perhaps that's not a very helpful answer! If you are wrestling with this issue of what our goals in ministry should be, then The Soul Winner w … [Read more...]
Faithfully Pursuing Fruitfulness
Don't read the Puritans, read Spurgeon!
This post was a guest post about Spurgeon, surprisingly enough given my current interest in him over at Desiring God's fabulous blog. If you don't read that blog already, I urge you to do so. I must confess to having slightly overstated my point in the title of this post. I rejoice in the recent resurgence of interest in the Puritans, who have so much to teach us. Perhaps a better way to capture the thought propelling this post would be "Use Spurgeon to Create a Bridge to the World of the P … [Read more...]
"No God? I live in him!" Spurgeon's divine experience
In this quote from Spurgeon he reveals a depth of spiritual experience that frankly surpasses that of the vast majority of Christians today, whether charismatic or cessationist. But surely we can and should all aspire to know something of the depths of experience he knew?"Beloved brethren and sisters in Christ, I think that you and I can say, that to us the surest fact in all the world is that there is a God. No God? I live in him. Tell a fish in the sea there is no water. No God? Tell a man … [Read more...]
Help us make a documentary on the life of Spurgeon
A few weeks ago, Steve McCaskell approached me with an interesting idea to crowd source funding for a full-length high-quality documentary on the life of Spurgeon. He had already raised almost $9,000 on his first crowd-source funding to support the publication of a book of Spurgeon quotes, Through the Eyes of Spurgeon.Crowd sourced funding is simply a way to take the financial risk out of big projects like manufacturing a new product, or in this case producing a film designed to inspire a … [Read more...]
Spurgeon's last words from his last sermon
I thought I would share the following which constitute the final words of the final sermon Spurgeon ever preached. There are many other sermons that were published later than this in the published volumes, as they kept publishing them after his death. These are fitting words to close such a remarkable ministry: Was he not a good Lord when he first took us into his army of salvation? What a curious crew they were that enlisted under David! "Every one that was in debt, and every one that was dis … [Read more...]
Facts about Spurgeon 121 years since his death
121 years ago today Spurgeon died. 100,000 people lined his funeral route to mourn the passing of one of the Victorian era's most significant public figures. You could do a lot worse than signing up for a new email devotional that begins tomorrow which is a lightly edited version of one of his devotional books.It seems highly unlikely that Spurgeon will ever be surpassed either in his influence as a preacher, or in his unrivalled status as the most prolific and most-read christian author of … [Read more...]
Spurgeon on receiving the whole counsel of God
How easy is it for us to become lop sided in our faith? The answer is very easy! One of the goals I have always had in blogging is to expose myself and others to people who might emphasize different aspects of the truth to us in order that we might grasp the full counsel of God. It is this idea that lays behind some of my "spectrum" posts (see for example my Arminocalvinist, Complementarian-egalitarian, and Charismatic - cessationist posts)Sometimes it may even be necessary to LISTEN to s … [Read more...]
Spurgeon e-mail devotional
I want to today introduce to my blog readership a new friend of mine, Stephen McCaskell. We have a top secret project we are working on together that will be revealed shortly! Getting to know him I have been impressed with his entrepreneurial spirit, and his enthusiasm that a new generation should be introduced to the prince of preachers. You can and should follow him on Twitter, join his Spurgeon Facebook page, read the Spurgeon quotes page he runs, as well as his new blog here on P … [Read more...]
New book of Spurgeon quotes
I have recently got to know the bundle of productive energy that is Stephen McCaskell. He has compiled an excellent book of Spurgeon quotes categorized by subject and Bible reference. If you are looking for a Christmas present for a preacher, look no further, go BUY IT NOW! Here is what I said in my endorsement:This book will introduce a new generation to the prince of preachers. Many of these quotes are short enough to fit into a post on Twitter, but some are powerful enough to change the … [Read more...]
The Apostle Paul's Blogging Checklist, Hell, and Rob Bell
Now that Rob Bell's controversial book Love Wins is on sale on both sides of the Atlantic and many other comments have been made, I am feeling like I cannot avoid engaging in the controversy, or at least should read some more material to understand it better. I did not seek out such involvement, as you can see from my post which ironically listed Five Reasons I hadn't previously blogged about Rob Bell. Since then I have posted a couple of highly relevant articles without directly addressing … [Read more...]


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TORONTO (Reuters) - Canadian Finance Minister Jim Flaherty said on Sunday a sharp slowdown in the economy since the start of the year doesn't threaten the government's deficit plans.
"We're seeing the growth we thought we would see overall this year. We're on track," he said in an interview on CTV's Question Period. "We had very strong growth in the last quarter of last year and the first quarter of this year, more moderate growth, since then."
Canada's economic growth rate faltered more sharply than expected in the second quarter due to a slowdown in consumer spending and a weaker trade performance.
Flaherty said the recovery is fragile and he is particularly concerned about the weak U.S. economy, the destination for most of Canada's exports. But he said Canada's economic and fiscal fundamentals are in relatively better shape.
"We don't have a situation where we can't get to surplus. We can in the intermediate term. So I want to stay on track, make sure we stay on that track," he said.
Canada will release an update on Monday of the government's two-year, C$47 billion ($45.6 billion) stimulus plan. Flaherty said about 97 percent of the projects being funded by the plan are underway. But he repeated the government does not plan to extend funding for projects that run past deadline.
"The economic action plan is for a period of time. It's public stimulus, it's taxpayers' money being used to create jobs and protect our economy, but it doesn't go on forever," he said.
Reporting by Jeffrey Hodgson; editing by Philip Barbara


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November 27th, 2006
Dr Petra
Well whaddya know, a new 'survey' out today suggests ¾ British parents don't know whether their children are having sex or not. Probably making them like most other parents in the world.
The study, commissioned by Teachers TV is designed to attract attention to a forthcoming debate the TV station has planned on sex education on 6 December (at 9pm if you're interested). There's nothing wrong with debating this issue, but you'd have thought a channel devoted to good educational practice might have consulted the literature on this topic first, which tells us the following…
- Most parents would like to talk to their kids about sex but don't know what to say, or how/when to introduce the topic
- Most parents approve of schools delivering sex education (although not always about the range of topics that could be covered)
- Parents often feel they should wait until their kids come to them to ask for sex advice, rather than initiating sex education when their children are young
- Some parents lack basic sex education themselves so may provide incorrect or misleading advice to their kids
- Parents may fear talking about sex encourages sexual behaviour
- Some parents, particularly from ethnic minorities or more conservative communities feel discussing sex is the same as having sex, so whilst they want their child to ask about sex they also feel it's appropriate to punish the child for said interest
- Not all young people want to learn about sex from their parents and both parents and kids agree some taboo topics (e.g. anal sex, blow jobs etc) are probably not what they want to talk about together
- Parents are often more keen to talk to girls about puberty, periods and pregnancy but assume boys are 'naturally' sexual so fail to offer them advice or help
- Young people feel school sex education focuses too much on the mechanics and biological aspects of sex and not enough on emotions, feelings and how to negotiate relationships
Sadly Teachers TV instead decided on their own survey that revealed
½ (or 44% depending on which part of the release you read) had never talked in detail about sex with their child
74% didn't know if their child was sexually active
63% of parents did not want their children to have sex education lessons until they were over 11 years old and only 30% were happy for them to be taught about sex between 7 and 10 years of age.
86% felt secondary school kids should be taught about contraception, 80% were happy to discuss emotional aspects of sex, and 83% approved the mechanics of sex being taught
77% disapproved of dogging, bondage and cruising being taught (although some reports have claimed over ¼ of parents want 'kinky sex' taught to kids)
27% did not want homosexuality covered
Nothing particularly groundbreaking there, but let's just look at the quality of this data. Simply asking parents if your child is having sex is very likely to produce a fairly honest 'don't know' answer. Whilst parents with teenagers might hope their child isn't having sex, most may assume they might be at least thinking about it. So this doesn't really show a deficit in knowledge. Without analysis of answers by the age of the parent's child the data also is meaningless since a parent with a very young child is far more likely not to know if they're having sex than an older adult. And this study implies they were only given 'don't know' or 'yes' answers since there's no indication parents said 'no' to the statement about their child having sex in any great numbers.
It's also difficult to take this at face value since a parent may well not want their child taught about contraception or sexual activity before puberty, but may be happy for them to know about gender differences, how babies are made and how to be confident about your body which comes under sex education and can be taught to younger pupils.
Whilst it's normal to think parents would disapprove of bondage or dogging being taught, this study implies such topics are on the national curriculum. Not only is sex education still not mandatory, and is delivered in a hit-and-miss way, but topics such as dogging or cruising are not routinely taught in schools and this only serves to stir up anti-sex education arguments.
So we know that Teachers TV can't use evidence, but it seems they also can't interpret their own study data. The station's chief executive, Andrew Bethell, claimed his research showed parents weren't doing enough to get to grips with the problems of underage sex: "Our research shows that parents have their heads in the sand when it comes to their child's sex education and expect teachers to deal with even the emotional and relationship aspects of sex…We need to wake up to the situation of increasing teenage pregnancies, particularly amongst the very youngest, and recognise that a child's sex education has to be the joint responsibility of parents and teachers."
Now within these findings there's nothing to say that parents aren't being responsible. They were asked their views about school sex education and they gave them. There's nothing in these answers to show a 'head in the sand' mentality (although no doubt amongst some parents it exists). Whilst evidence shows parents need to play a role in sex education, without support or training this is unlikely to happen. Research indicates parents and teachers alike can be good, or really bad at delivering sex education. Rather than it being either schools or parents who are responsible, both groups need to deliver sex education, although unless we tackle wider cultural issues of media sexualisation and peer pressure sex education from home/school alone will not be enough
Okay, so Teachers TV can't use evidence, don't understand how surveys work and can't interpret data, but press coverage also showed they can't add up since the survey was promoted as based on a sample of 'nearly 1000 parents' but additional news reporting showed it was actually of 800 people and even with my dreadful maths skills I can tell that's 200 less than 1000!!
So Teachers TV, before you plan your TV debate or other promotional activities stay behind after school and write out for me 1000 times 'I will learn how to use evidence, understand surveys and add up correctly'.Tweet
Comments are closed.


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MORGANTOWN, W.Va. (AP) Two relatives of men who died inside the Sago Mine last year said the union's new theory about the explosion's cause provides answers they have long wanted.
Debbie Hamner and Ann Merideth said they never believed the conclusion of state investigators and the mine's owner that lightning triggered the methane gas explosion on Jan. 2, 2006. More likely, the women say, is the union's belief that the spark came from friction in the mine's deteriorating rock roof and the metal support system used to hold it up.
"I feel in my heart that this is the truth," the widow of George "Junior" Hamner said Thursday after a news conference in Washington, D.C. "It helps because I just want the truth. And I don't think we've been given the truth until today."
The blast killed one miner instantly and trapped 12 others underground in poisoned air for more than 40 hours. Only one survived.
Hamner and Merideth, daughter of miner Jim Bennett, said that if federal regulations had been enforced, the crew would have left the mine alive.
"We have just been through sheer hell, and knowing that my dad didn't have to die — it breaks my heart," Merideth said.
The mine's owner, International Coal Group Inc., dismissed the United Mine Workers' report as "wholly unreliable" and as "political grandstanding" meant to bolster organizing efforts.
Two previous disaster reports — one by the mine owner and the other by the state mine safety office — identified lightning as the most likely cause. A third, by a former federal mine-safety chief, said lightning could not be ruled out.
A lightning strike was documented at about the same time as the explosion. But unlike other coal mine blasts linked to lightning, Sago had no metal conduit that could have carried the charge that far, according to the union, which participated in the Sago investigation as a legal representative of several workers at the non-union mine.
The federal Mine Safety and Health Administration has yet to release its own findings about Sago.
Sago Mine is a non-union operation, but a federal judge let the union represent several workers in the investigation.
Copyright 2007 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
Conversation guidelines: USA TODAY welcomes your thoughts, stories and information related to this article. Please stay on topic and be respectful of others. Keep the conversation appropriate for interested readers across the map.


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The Eating Disorders Coalition advances the recognition of eating disorders as a public health priority throughout the United States. If you are impacted by eating disorders, be it as a sufferer, family member, friend, treatment provider, or in other ways, we invite you to become part of the solution to the problem by joining forces with the EDC.
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GR Radio Pervert Balyo describes his crime in Federal Court
courtesy photo
He called his Christian Radio Program "Family Friendly" He was anything but. Appearing in Grand Rapids Federal Court today John Balyo will be required to describe in details the crimes he committed against children. Most of his testimony will probably be unfit for broadcast. He will be sentenced to 15 to 50 years in prison. At best he would be 50 years old before he is released, if he does his full sentence he'd be 85. Of course he still faces local charges in Calhoun County and a local conviction would probably keep the pervert in prison for the rest of his life.
Homeland security officials said when he was arrested, Balyo was on the verge of even more serious crimes.


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Disclaimer – I do not own Digimon, nor do I claim to. And if I had any money, or a life in that matter, I wouldn't be sitting at the computer 24/7 P
Author's Notes – Yeah, I like being different...but this fic shows how different I can go ^_~
Couples/Warnings – Daisuke/Jun. See? I told you I this fic was different. Short, one sided POV fic. I'm sure you'll figure out who it is :P Anyway, small incest warning. You were warned, so if you go ahead and read, its your own fault o.O;
"Another Friday night, another night at home." I sigh, staring at the blank television.
Outside, the sky burned a brilliant red as the sunset and dusk set in. The dimming light was the only thing that lit up the room, and it was growing darker with every growing moment. Normally a sunset would have brightened my day, for I loved them. To me, sunsets were one of the most romantic scenes in the world, and I enjoyed them every time I had the time to stop and watch. I could sit on the balcony for hours, just watching the glowing red sky. But tonight I didn't feel like watching it; I didn't feel like watching much of anything.
Besides the sunsets, my most favorite thing was to get out of the house and forget who I am, where I live, and mostly, him. But tonight was the start of a long line of nights home alone, especially after letting my former boyfriend, Yamato, go. Then again, he really wasn't my boyfriend to begin with. I was so caught up in trying to forget the real person of my dreams, that I came to believe that another boy could really love me.
You see, as much as I didn't want to believe it, Yamato's heart belonged to someone else, even before I came into the picture. But again, I let myself believe that he was interested in only me, when his heart truly lay with his best friend Taichi Yagami.
Although this bothers me somewhat, that out of all the fan girls out there, and believe me, there are quiet a few, that Yamato would pick his best friend – a boy, over them. He was a rock star, and he could have absolutely any girl he desired. But in the same way, I'm relieved and happy for him. He didn't have to hide his true feelings from his friends and family like I did; especially my family.
What would my family think of my little secret? That he fills every my every dream, every moment, every breath. That I have hidden feelings, secret desires for my own little brother? I suppose they'd just brush it off as brother-sister love, but I know it's much more than that. What kind of sisterly love would make my heart stop every time I look at him? Fill my thoughts with just him and only him? Make me want to yell and scream at him for feeling this way about my own brother...
And that's what I do. As much as I hate it, I yell and push him away as far as I can because I'm afraid. I'm afraid of what will happen if I let the feelings take over, and what I might do. What would poor Daisuke think of his sister then? I know he already hates me...at least, I think he does. I try my best to make him hate me. It's easier on me that way. The less time he spends around me the better. Maybe its just a phase that I'll grow out of – at least, that's what I'm hoping.
But these feelings have yet to cease, and I've been living with them since I can remember; probably just as long as I have been living with him. I must be really sick...I mean, how many other girls can truly say they love their brother, much more than brother – sisterly love? Again and again I tell myself that these feelings are wrong, that its incest. But then he looks at me with those big brown eyes and all thoughts melt away. There are times I wish he wasn't my brother...that maybe I'd have a chance then. Then again, he's already found that special someone in his life as well.
Who'd ever thought that Daisuke Motomiya, my little brother, would fall in love with the one and only Ken Ichijouji? I wouldn't have thought that my brother would be that way...not in a million years. He'd used to have this thing for a girl named Hikari – I believe she's Taichi's sister. Yes, Hikari Yagami, that was it, and back then I was tired of hearing her name. I doubt there was ever a word that came out of his mouth that didn't have to do with that girl, and I had tried my best not to listen, to make my own pain go away. And then there was Ken – who stole the once solid ground from under his feet and my brother fell head over heels in love, and they'd stayed that way. That's where my brother was now – out with him to see a nice romantic film. What I'd give to be in Ken's place...not to worry about who I am, or that I'm in love with Daisuke...but my dreams and wishes will never come true. I'll always be Daisuke's big sister...the big annoying sister who still gets on his nerves, who picks on him constantly, and is truly and utterly in love with him.
Sighing, I snap out of my thoughts. The last few rays of light are peeking in through the curtains, and the room is dark. But instead of moving to turn on the light, I turn to look out at the last of the remaining sunset. It's as beautiful, just as it will always be.
And here I sit by myself as the darkness takes over, and red fades to dark blue. All good things must come to an end...and the sun will always set, leaving you in this darkness of despair. I can only hope that things will get better over time...and my pain will slowly fade into the darkness...just like the sun. And with the new day, the sun will arise again, starting its journey across the sky just like every other day, only to disappear again.
The sun may always set, but it will also bring a new hope, a new experience, a new feeling.
A new day.
The End
Told you it was short...and it probably sucked just as well ^^; Anyway, I tried doing something different, and I succeeded...so I'm still happy ^^;


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Doctor insights on:
What Happens When You Pass A Kidney Stone Vomiting
Back/side pain nausea/vomiting chills. Diag w/large dense kidney stone 4 yrs ago was told it would never pass, is it trying to or something.
YES: SOMETIMES this situation (large kidney stone) can deteriorate due to INFECTION behind it!! You need immediate evaluation in ER!!!!! Go ASAP Good Luck Hope this helps! DrZ ...Read more
Kidney (Definition)
The kidneys are paired organs that lie on either side of the vertebral column. Part of their critical functions include the excretion of urine and removal of nitrogenous wastes products from the blood. They regulate acid-base, electrolyte, fluid balance and blood pressure. Through hormonal signals, the kidneys control the ...Read more
Husband had kidney stone zapped this morning,got instructions4 after care,but nothing said about vomiting.about 20 minutes ago.Normal?????
Here are some...: Uneventful zapping procedure for u-stone itself would not cause nausea/vomiting; but the nausea and vomiting as side effects from anesthesia for such procedures are not uncommon. So, take a good rest and see for 4-6 hours. If not improving as wished and expected, seek timely professional evaluation especially with fever. ...Read more
Husband having kidney stone hasn't passed after 15hrs pain pills not helping vomiting not eaten can't drink. Er?
Kidney stone: Given that it is a weekend - yes go to the er perhaps they can get the urologist in to see him. He probably needs it taken out. ...Read more
Bright red vomit smell is awful vomited black last week hospital didn't find anything except small kidney stone. Not holding down meds?
Vomit blood: This is indicative of GI bleeding. PLease get this person to the hospital right away - there is active bleeding especially if the vomit is bright red. ...Read more
I am passing a kidney stone. Since this morning I have been nausea, vomited once, flank pain and frequent urination. ?
Typical symptoms: The symptoms you describe are typical when you pass a kidney stone. Make sure you are drinking plenty of fluids. See your doctor to ensure you do not have an infection and if you need any pain medication. ...Read more
Are kidney stones associated with vomiting?
Yes: A symptomatic kidney stone can cause nausea and vomiting. If it is severe, please go to the nearest emergency room to be evaluated and treated. ...Read moreSee 1 more doctor answer
I have had kidney stones for a month, been to the ER 4 times. Have had a fever, vomiting etc. Von whilibrands diseases, patela replacement, full hystrorectomy
Kidney : Kidney stones can be quite painful as you know, if associated with infection they can be lethal due to sepsis. You need to see a urologist asap. He may place a stent to divert urine around the obstructing stone. You may need to be treated with antibiotics and possibly hospitalized. ...Read moreSee 1 more doctor answer
Having pain on right side of stomach that feels like I'm being popped by a rubber band from the inside. And vomiting. I've had 20 kidney stones in 2 y?
Renal colic : Your symptoms are certainly consistent with kidney stone passage. It sounds like you should have imaging with X-ray, ultrasound or CT scan. Also, if you have had 20 kidney stones in 2 yrs then you definitely a metabolic stone evaluation. See a urologist. ...Read more
Can you pass a kidney stone without knowing it?
Yes: Small stones may pass with no symptoms whatsoever. ...Read more
Kidney Stone (Definition)
Solutes precipitate and combine to form stones formed of calcium oxalate usually around a nidus of uric acid. Other solutes that form stones are ca and mg phosphates, cystine, and uric acid staghorn calculi form in the presence of chronic urinary tract infections. Stones can be painful, may require ...Read more
Vomiting (Definition)
Nausea is the sensation of having an urge to vomit. Vomiting is forcing the contents of the stomach up through the esophagus and ...Read more
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- When you pass a kidney stone what happens
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ZE:A has just released individual concept photos from their upcoming special single, "Watch Out", a real treat for fans who are patiently waiting for the official release on July 8th.
With Jeju Island's scenery as their backdrop, the nine members are dressed from head to toe in white for a comprehensively fitting look for the hot summer.
The group promises a brand new start with their comeback and 200% of their efforts for 'Heart For 2'.
Star Empire said, "ZE:A will be releasing their songs digitally on July 8th and make their official comeback through KBS's 'Music Bank'. We worked to emphasize the sides of ZE:A that weren't seen before. It's a new special single after 'Here I Am', so please look forward to it."
Source: Star Empire Daum Cafe


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