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High Blood Pressure
I use pharmacy strength hydrogen peroxide -- drops in glass of water twice a day (about 7 drops thus far). My moderately elevated blood pressure reduced to normal, according to my doctor's records, without use of drugs. How long should I continue to pursue this treatment? Should I continue longer or cycle on and off in some way?
Even though I know that one and all will be hesitant to claim that H2O2 does in some way help for the Human Immunodeficiency Virus,or for that matter aid towards the destruction of it, I would like to know if anyone out there ever tried h2o2 for this and what their personal results were.
Joelton, Tn
516 posts
Freemindville, World
Hello someone asked the question about oxygen therapy with hydrogen peroxide and HIV.
First off you know only propaganda and lies about HIV. NO offense to you and 3 billion other people. Don't feel bad. HIV is harmless. We don't know how long Hiv has been in human bodies maybe millions of years. After we had big microscopes we found it. Go to Peter Dunesbergs website. Try to go to Google video and search if they still have the videos the aids myth, or the aids hoax, 10 reasons why aids is..., aids fact or fiction, etc.
Theres a few good videos and I forget if the names I listed are 100% correct but it should get you to the right videos if they haven't all been removed, to cover up the truth. Ok in a nutshell Aids is caused by medication doctors give once they find HIV. Or by drug addicts breaking down their immune system from drug use. This includes gays who use lots of drugs or habitually take antibiotics cause the do anal sex. In poor countries Aids is caused by diareah malnutrition and once again, doctors drugs shipped to those Countries in mass quantities. Just watch the videos check out the websites and wake up from your brainwashing. Learn the truth the 100 billion dollar industry doesn't want you to know.
Truthville, World
Ps ben, this is my second comment I hope both get successfully posted.
Just to mention most of Africans are lactose intolerant and dont drink milk unless its human milk. If your drinking milk from milk powder or cows etc that can give diareah and other problems, which paired with malnutrion causes of aids in Africa. Same with doctors aids drugs. you can have harmless hiv that the drugs and get aids.
Ps no Cocain or those hard street drugs either. you'll get aids that way. 1 Nutrition and 2 ozone therapy or the Hydrogen peroxide will do and 3 detoxify yourself. Get some sulfur so your cell walls can absorb nutrients. I don't want to Talk forever. Do the research and good luck.
Cape Town, South Africa
Joyce from Joeltown: Run that therapy by me again (that is the urine therapy) please?
Anonymous from Truthville: Really we are no more lactose intolerant than the Britons or the Americans or the Chinese or the Canadians. However, I think one should start some research on the sulpher usage. Thank you so much
Joelton, Tn
516 posts
Hello Ben, To get a good rundown on the urine therapy, research it online. There is also a book written on urine therapy title is: "Your Own Perfect Medicine". The urine used is your own. I have no personal knowledge but did read in the book mentioned where some young man said he was not only alive, but feeling well using no therapy except for his urine l4 years after he read about it and decided to try it. It supposedly cures a lot of health problems. If you decided to try that route, urine is a sterile solution unless you happen to have a urinary tract infection. I believe it has also been used IV. Allegedly, in the battlefront hospitals in the last several wars, urine was given IV when plasma was unavailable.
Can't help you with the hydrogen peroxide. It has also been given IV for those whose stomachs will not tolerate oral HP. From what I have read on it, HP is said to cure a lot (if not all) chronic health problems. I can give a personal account of using Bill's inhalation HP. I find it opens your head & chest up so you can breathe easier quite quickly and I had no unwanted reactions or side effects. I wish I had known about it when I caught pertussis (whooping cough) from a patient. That was one time my 50/50 ACV/honey failed me. When I started coughing one night after returning to work, my doctor looked at me and said "Sounds like you need to see the lung man". As I told him, "I know it sounds that way, but the problem is in my head. Feels like someone is spraying glue over my trachea, and my lungs are just working hard to keep it out of my lungs." I think Neti potting the nose with saline to stop the drainage would have been the best way to handle it, but that was before I heard of a neti pot. However flushing the nose with normal saline stopped the cough longer than anything else did. If you want my personal opinion, using both HP and the urine therapy at the same time, would probably be a lot safer than taking the combination of drugs given for HIV.
Hamilton, Ohio
To Anonymous from Truthville, I find your remarks ill-informed and offensive. I contacted HIV via a HepB vaccine from a clinic using bad practices (reusing sringes). Your comments are flat out wrong. HIV is debilitating long term if you take no action to correct it. I've never done the drugs you mention, don't share needles or fall into any of the groups you mention. I'm otherwise quite healthy but without attention paid to this disease, it will kill you. Maintaining CD4 counts is a constant challenge. I've used herbal remedies, Beck Protocol, Ozonated water, MMS and H2O2. No cures yet but I'm still drug free and happy about that. I'm not anti-drug, I just know and want to avoid the side effects if I can. I think you should spend more time droning on about something you have some direct knowledge of or just hang out on the other conspiracy theory boards. I don't care how HIV came upon this earth. I don't care if big bad men at Fort Detrick invented HIV in the lab for population control or what. I just know I have it and want to get rid of it before it gets rid of me. H2O2 might be in part the silver bullet that we need. I don't know for sure. I'm definitely willing to try it.
Rio, Brazil
HIV is harmless... AIDS is caused by drugs (legal or illegal). The exception is Africa, where AIDS is caused by typical diseases of poverty (TB, malaria, parasite infestation, unclean water, malnutrition).
Forget HIV. There are a thousand good reasons to wear rubbers, but preventing AIDS is not one of them.
The discoverer of HIV (who won a Nobel Prize in 2008) had to say this about HIV:
It's a scam. It has been a scam since the early 80s.
Lagos, Nigeria
Please, Gringo from Hamilton, it is a pity that nobody has come to say that he has used the therapy for HIV, and it is ridiculous that you as a person have not tried it. i will urge you to try it and get us informed that you are cured, then we will start a crusade all over the word for the use of h202. i wish you all the best in health. I love you.
Torrance, California
To Ben (from Cape Town, South Africa): In answer to your question about hydrogen peroxide and HIV -- good news, according to Dr. David Williams' research on food grade hydrogen peroxide ( http://educate-yourself.org/cancer/benefitsofhydrogenperozide17jul03.shtml ), "the following is only a partial listing of conditions in which H202 therapy has been used successfully":
Allergies, Altitude Sickness, Alzheimer's, Anemia, Arrhythmia, Asthma, Bacterial Infections, Bronchitis, Cancer, Candida, Cardiovascular Disease, Cerebral Vascular Disease, Chronic Pain, Diabetes Type 11, Diabetic Gangrene, Diabetic Retinopathy, Digestion Problems, Epstein-Barr Infection, Emphysema, Food Allergies, Fungal Infections, Gingivitis, Headaches, Herpes Simplex, Herpes Zoster, HIV Infection, Influenza, Insect Bites, Liver Cirrhosis, Lupus Erythematosis, Multiple Sclerosis, Parasitic Infections, Parkinsonism, Periodontal Disease, Prostatitis, Rheumatoid Arthritis, Shingles, Sinusitis, Sore Throat, Ulcers, Viral Infections, Warts, Yeast Infections.
So "yes" H202 has been used to successfully treat HIV. I personally believe that praying and asking God to bless each thing you do will synergistically increase its power.
God bless you.
Hot Tubs
Hi, This information may be on your site somewhere but I haven't accessed it yet. I was wondering if you could tell me of a chemical free solution to keeping a hot tub. The therapeutic value of hydrotheray is nullified by the chlorine/bromide we have to use. I do have an ultraviolet light. Do you recommend food grade hydrogen peroxide?
Thank you
Lloydminster, Alberta
Virginia Beach, Va, United States
My husband and I no longer want to use chlorine and bromine and all the other toxic chemicals in our hot tub either. I've done a lot of research and hunting to find natural alternatives. I have found 3. We are trying the first one right now. I can't give any brand names or anything but I can tell you it is a colloidal silver. Emptied and cleaned the hot tub taking out all parts possible and cleaned with a toothbrush. Filled up the hot tub with tap water using a carbon filter. All I did was dump the 16oz bottle of colloidal silver and it's been sparkling clean for a month now. We use our hot tub every night. But here's the kicker. We do shower every time before we get in the tub. Bought 35% H2O2 and when I empty the hot tub after 3 months....I will try this method but I won't use the carbon filter to fill the hot tub with this method. The 3rd one I will try will be another natural product. All I do is dump one bottle in every 3 months and that is it. So far the colloidal silver product is awesome! No smell and we are so clean!
How to Use Food Grade Peroxide
I couldn't find any step by step testimonials so I thought I'd write one.
I bought 35% Food Grade from our local health food store & a gallon of distilled water. I measured out 1 1/4 cup of water, dumped that out and added 1 1/4 cup of H2O2 to make a gallon of 3% solution.
Never use the 35% straight in a glass of water. Only mix 3% solution in with your glass of water!
I started slow with three drops in a 20oz glass of purified water on an empty stomach. Because my schedule didn't allow me to drink it 3x a day, I only drank it once in the morning.
Now everyone's experience is different...here's what happened to me.
I experienced nausea...a lot of nausea. I had to gradual increase # of drops every day. If the nausea got to be too much I would reduce the drops until I could tolerate it and then start going back up. My goal was to drink 1 oz a day. Although I did reach this goal I couldn't maintain it. The nausea was too much, so I dropped down to .5 oz. I did this routine everyday for 2 months
Other symptoms included pooping a lot, anal itching, some sinus problems, head cold like stuff, intense fatigue in the afternoon, facial breakouts, some small rashes, back aches, joint aches and some headaches. Each individual symptom only lasted 3-7 days.
The good news: I did have a lot of energy in the morning and my mood improved. My Blood Pressure went from 132/90 to 115/90. My thyroid increased. My oral health improved. My gums were no longer bleeding and irritated and I didn't have any cavities (I usually have at least 1-3 every time I go), my appetite decreased, and I didn't crave junk food anymore.
I'm very thankful I found this website. It truly has changed my life for the better.
Humidifier With Hydrogen Peroxide
How many drops of 3% food grade peroxide to add to air concentrator humidifier bottle half full ( about 8 oz.) for disinfection. Don't want it so strong it burns my sinuses or lungs or can taste it. Appreciate any help.
Hydrogen Peroxide Additives
Well here's something interesting that I've just found. I use HP quite alot, looks like the FDA are trying to squeeze out HP for internal use completely. Probably part of their Codex Alimentarius tactics. It seems that perhaps even food grade HP may not even be so safe from additives. Here are some extracts:
"Food grade and Technical grade hydrogen peroxide are essentially the same. However, the FDA regulates among other things the processing of Food grade hydrogen peroxide.
For Example:
The manufacturer produces 10 drums of technical grade H2O2. He would test the first and the last drum for quality and purity. The FDA inspects or test all 10 drums. All 10 drums are now considered to be food grade H2O2 after the additives added by the manufacturer for compliance. If the packager pours food grade H2O2 out of one of those drums into a smaller container, it is no longer a "food grade" unless that smaller container is also tested for the FDA compliance."
"Hydrogen Peroxide Grades
3% Hydrogen Peroxide (Drug/Grocery Store Variety)
Used as antimicrobial agent for treating wounds and sanitizing agent
[Made from 50% Super D Peroxide, Diluted. Contains stabilizers - phenol, acetanilide, sodium stanate, tetrasodium phosphate among them.]
[This peroxide contains known chemicals do not ingest!]
6% Hydrogen Peroxide
Used by Beauticians for Coloring Hair. Used as sanitizing agent.
Comes in strengths labeled 10,20,40 volume. Must have activator added to be used as a bleach.
[Contains stabilizers, additives, and impurities dependent on manufacturing and dilution process. Do not ingest.]
30% Re-Agent Hydrogen Peroxide
Used in medical research.
[Contains stabilizers, additives, and impurities dependent on manufacturing and dilution process. Do not ingest.]
30-32% Electronic Grade Hydrogen Peroxide
Used for washing transistors and integrated chip parts before assembly.
[Contains stabilizers, additives, and impurities dependent on manufacturing and dilution process. Do not ingest.]
35% Food Grade Hydrogen Peroxide (Also 50% Food Grade H2O2)
[....*....]. Also used to spray inside of foil lined containers for food storage - known as the aseptic packaging system. [...*...additional information removed for FDA compliance]
[Contains stabilizers, additives, and impurities dependent on manufacturing and dilution process.
--e.g. This Food Grade Hyrogen Peroxide is Stabilized using tin based formulations ]
35% Technical Grade Hydrogen Peroxide
Used for waste water treatment and the disinfection of potable water, cosmetics, and laundry applications. [...*...additional information removed for FDA compliance] [May contain a small amount of phosphorus to neutralize any chlorine in the water it is combined with.]
MATERIAL SAFETY DATA SHEET & Technical Details: Hydrogen Peroxide (20 to 40%)
35% Standard Grade Hydrogen Peroxide (Also 50%, 60%, 70% Standard Grades)
Used mainly for bleaching in the pulp and paper industry and in the textile industry; oxidation reactions in the chemical industry; environmental processes (detoxification and deodorization). Used for Waste water treatment.
[Contains stabilizers, additives, and impurities Do not ingest.]
90% Hydrogen Peroxide
Used by the military as a source of Oxygen at Cape Canaveral. Used as a propulsion source in rocket fuel.
99.6% Hydrogen Peroxide
This was first made in 1954 as an experiment to see how pure a hydrogen peroxide could be manufactured. "
It seems that even food grade HP will have stannous or tin stabilizers in it at a minimum. This won't stop me using HP though, since I only use drops anyway, but the article is interesting.
Hydrogen Peroxide and Birth Control
Hello, Can one continue Hydrogen Peroxide therapy, while using the NuvaRing? Do you know if there would be any issue or adverse health?
Hydrogen Peroxide and Black Tongue
I have sung the praises of hydrogen peroxide for years. It literally cured me of COPD. Everything good you read about it is true. However, this one little matter: I began to have a black tongue and have had it now for some years. I wrote in here at the time I was helped with the COPD that I did seem have a black tongue and no answer for it, but I said "if that's all I have to pay for the cure, fine by me." But all these years later, I got the answer. It's the peroxide. It affects some people that way. So I'm back to what I said years ago - "If my only problem is black tongue, but cured otherwise....fine by me."
Hydrogen Peroxide and Stabilizers
My question is for Ted/Bill, I have asked this question earlier also but so far no answer has been given to me, and it is very important for people living in India. I have even gone to people who make H2O2 and they have told me that demand for food grade H2O2 in India is so little that it is not viable for them to make it and it is very unstable so if they make it and is not sold, it is total loss to them. I therefore had requested Ted/Bill to give their advice whether one can take the normal (non food grade) H2O2, as we are taking Borax which is for lab use only. Why I am emphasising this question is that we in this part of the world are being deprived of the benifits of H2O2. How harmful are the stabalisers which they put to make H2O2 stable for lab/external use only? Ted/Bill please take some time to answer my question so that once for all this subject can be taken out of my mind one way or the other.
Thanks Baldev
Somewhere, Europe
Hydrogen Peroxide and Vitamin E
Ive read the instructions on how to take hydrogen peroxide and it says to also take Vitamin E while you are doing the treatment. Do you take the Vitamin E before , during, or right after you take the dose of h2o2? I know you're not supposed to eat anything 3 hours before or an hour after taking h2o2
Hydrogen Peroxide Baths
Here is my experience so far using hydrogen peroxide:
I started a month ago, trying out the baths, the inhalation method, and also the food grade drops internally. For anyone who is worried that the h2o2 bath is less useful since it's used externally, don't worry about that. The baths work just as effectively. In fact, I've had to taper off the number of bottles (32oz at 3%) I use per bath, from 4/day to just one, because my detox symptoms started to become pretty bad. I've done a lot of metal detoxes, and I recognize from those the same anxiety and flu-like symptoms when my body can't clear out the toxins fast enough.
Anyway, for me drinking the drops in water led to a lot of nausea which was a deal breaker, so I stopped. The throat spray seems to have been incredibly powerful, but I stopped doing that as well since it irritated the back of my throat. The good news is, if you have those problems, you can easily get the same results from the baths alone. And they make my skin look excellent as well.
What I want to mention though is this: it is possible to overdo it! Someone else on this site wrote about a "hang over" effect from the h2o2, and I think that must be what I've had? I believe that the h2o2 is building up over time, and that it needs enough space between doses to clear itself out? Has anyone else had a similar experience, finding the upper limit on the dose they can handle? And what happens after that?
Overall, it seems that my muscles and joints are less rigid than before I started. I'm taking the h2o2 for persistent low level arthritis and fibromyalgia. Thanks so much earthclinic for providing such valuable information!
I want to try Hydrogen Peroxide baths. I would like to know how often should I have them. Everyday? Every week? I would appreciate any input that anybody might have. Thank you in advance.
Hydrogen Peroxide Capsules
Does anyone know if the Zero2Sixty Oxylife capsules work and also Earths Bounty Oxycaps? they both have good reviews on Amazon the only difference seems to be (besides the price) is the Zero2Sixty lists only 35% food grade hydrogen peroxide as the only ingredient and oxycaps lists sodium, potassium and calcium as ingredients, I would personally think the zero2sixty would be better for breathing problems. does anyone have any suggestions?
The Oxycaps are essentially oxygen "precursors" of Sodium Chlorite w/ potassium and calcium stabilizers or buffers. With adequate or higher levels of these nutrients, the body naturally produces "more" oxygen than normal. I would recommend the Oxycaps taken first and if necessary add the H2O2 products to maximize O, probably in about a 2:1 ratio.
Illinois, US
Hydrogen Peroxide in Humidifier
I'm reading all this wealth of information on earthclinic.com about HP and respiratory issues. I want to try what I learned on my 3.5 year-old-son who has pnueumonia. Then I got to thinking, would putting HP in the air humidifier be an effective way to transport the it into the breathing ways leading into the lungs?
I couldn't find any discussion on this topic, and hoping to start one with this inquiry. Thanks!
Tauranga, New Zealand
Just a word of caution: Humidifiers are known to be extremely bad for health, whereas de-humidifiers are safe. The best ways to humidify a home are as such: 1) Place as many plants as you can fit onto your window ledges. The plants will release moisture into the air through transpiration. 2) Once you've finished in the bath, leave the water overnight to cool and some will evaporate into the air and humidify your home. 3) Place bowls of water in rooms of your home, these will evaporate eventually, then just refill. 4) Try and do as much cooking on a stove top rather than in the oven. The stove top cooking allows moisture to be released - the oven will dry your home out.
p.s. not to mention you'll save heaps on electricity!!
Indiana, Usa
Hydrogen Peroxide Therapy and Supplements
Hydrogen peroxide therapy and accidental iron intake: Just realized that our brand of multi-vitamins added iron (10 mg) to it's formula. I've been doing the hydrogen peroxide treatment (ingesting) and am now scared that I may be hurting rather than helping myself. Have of course stopped the vitamins. Any advice or thoughts on this? Should I stop the treatment completely? Seems like you can get added iron in your diet in multiple ways (cereal, etc.) without realizing it, so I'm sure some of you others must have dealt with this. Any help will be much appreciated!
Ky, Usa
Lizajane: Vit-C is very important for the assimilation of synthetic iron supplements, so do make sure this brand also includes the Vit-C or find a brand without iron and be sure to eat at least 1 serving of cooked liver per wk and/or Blackstrap Molasses (BSM) as these two foods are the best forms of Iron. A B-12 w/ Folate will help the body use the Iron for the production of Red Blood Cells. A broad spectrim Vit-E suplement will greatly increase the lifespan of the Erythrocyte thus reducing the need for Iron.
As for the H2O2 therapy, be sure to first alkalize the body to maximize the Oxygen levels in the cells. Also, if you are using the H2O2 for infection issues, I would rotate, on a weekly basis, w/ herbal antibiotics like Neem, Oregano, Olive Leaf, Garlic.
Id, Usa
Thank you for answering, Timh. I will try your suggestions. My body definitely doesn't need MORE iron (according to lab work), so I avoid it in supplements. I'm on the hydrogen peroxide therapy for sinus problems and general preventative (ex-smoker, fibromyalgia, etc.) and am up to 21 drops 3 X daily, so I really don't want to stop now..too hard to get here! Just wasn't sure how much damage that multi-vitamin with iron might have caused. I do get lots of Vit C. Thanks for your thoughts...past and future.
Ky, Usa
Lizajane: It is difficult to determine what oxidative damage might occur w/ the H2O2, and this therapy should only be temporary; that's why I suggested the herbal antibiotics for rotation. As for general protection, which seems appropriate in your condition, continue your H2O2 course and monitor for results, but eventually what your body needs firstly is nutritional antioxidant protection. This is an entire science in itself, so do familiarize yourself and begin fortifying your body.


text:
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subset: commoncrawl


text:
+ one boy from Maine
+ one boat on the
+ a search for a great bear
+ 3.14 (pi)_________________
= The journey of a lifetime
After his mother's death at the end of World War II, Jack Baker is suddenly uprooted from his home in Kansas and placed in a boys' boarding school in Maine.
Feeling lost and adrift, Jack can't help being drawn to Early, who refuses to believe what everyone accepts to be the truth about the great Appalachian bear, timber rattlesnakes, and the legendary school hero known as the Fish, who was lost in the war.
When Jack and Early find themselves alone at school, they set out for the Appalachian Trail on a quest for the great black bear. Along the way they meet some truly strange characters, several of them dangerous, all lost in some way, and each a part of the pi story Early continues to reveal. Jack's ability to be a steadfast friend to Early will be tested as the boys discover things they never knew about themselves and others.
Navigating Early is a story that will challenge and astound readers as they navigate mysterious and uncharted lands.
(From the book jacket)
January 10, 2012
One year ago today...
I received amazing news. It's not the only time I've received wonderful and life changing news. Other times:
18 years ago, the doctor said, "It's a boy!"
16 years ago, "It's another boy!"
14 years ago, "It's a girl!"
11 years ago, "It's another girl!"
9 years ago, "It's a dog!"
7 years ago... well, that must have been a slow year in the world
of amazing news, but you get the gist.
Still, January 10th, 2011 will forever be a day I will remember and celebrate. A day that will give me lots of opportunities to say to my kids, "See, amazing things happen... and they can happen to you!"
This past year has been filled with many wonderful experiences. Of course, one of the most special was the ALA conference in New Orleans where I received the Newbery Award. My family came out in full force, i.e. my husband and four kids, my sister, her husband and their four kids, and my mom and dad. I joked that we were like the Clampitt's riding into New Orleans. No, we did not strap Grandma to the top of the 15 passenger van, but we certainly felt like we had struck it rich and really enjoyed the cement pond at the hotel.
I've met many wonderful people, spoken at lots of schools and conferences, gotten some great fan mail. One of my favorites was from a 4th grader who told me he was glad that Kansas was now known for something other than basketball and weather! That's big noise, especially since Kansas is pretty much the birthplace of basketball.
So 2011 was a wonderful year but not only because of a special award. Other big events: Lucy got her braces off. Paul got his braces on. Luke crammed 80 high school kids in our garage for a dance and everyone survived. Grace's singing has not broken any windows... yet. (Lucy made me put that.)
And I finished my next book! It is called Navigating Early and will come out next spring. More on that soon.
So, life goes on and life is good.
April 2011
Okay. I've procrastinated long enough. Actually, I wouldn't call it procrastination. I just haven't wrapped my brain around the fact that people I'm not related to are actually reading my website.
I had a fun time creating this website last summer in preparation for the book coming out and part of that was because I approached it as if I was just talking to my sister, my kids, or my friend across the street.
Then January 10th rolled around and the Newbery seal went on my book, and all of the sudden people were e-mailing me, telling me something they had read on my website. I think that's when I froze up a bit and I gave myself the excuse of not updating it because I had to write my Newbery acceptance speech. Or I needed to prepare for upcoming speaking engagements. And those were valid excuses. But then, they became a little less valid – like I need to fold some laundry. Or I need to let the dogs out. Or I really need to change out that roll of toilet paper.
That's when I realized I had a bit of writer's block regarding my website. So I decided to go to go back to what worked the first time. I'm just going to write as if I'm talking to my sister, my kids, or my neighbor across the street - and just tell you what's been going on in my world lately.
In a nutshell, life has been wonderful, crazy, and very busy. I've had many invitations to speak at schools, conferences, book festivals. What a thrill to get to talk to so many people who are very excited about my book!
In fact, I would have to say that one of the most unexpected and most wonderful results of winning the Newbery has been the way my local community in Wichita and people across Kansas have embraced the book and celebrated this wonderful honor with me. It's like there's this big Newbery train and everyone feels free to jump on. And I love that!
I also love the fact that I've had some great help. While I was in New York immediately following the Newbery announcement, my sister and our good friend CY (C.Y. not sigh) came up with a To-Do list to help me in those busy days. Things like #4 – Make new business cards. #7 - Start a scrapbook. And my favorite one, #13 – get pre-loaded credit cards for CY and Annmarie.
We set up weekly meetings to help keep me organized. They consist of Annmarie and CY showing up at my house asking, "Is the coffee on?" Or "Can I fix myself an egg?" Then Annmarie's kids eat their breakfast at the counter and CY's son tells us how the Wichita State Shockers are doing. As soon as everyone's fed, the kids go off to play or watch a show and I clean up the kitchen. Then we start to discuss something, like updating my website, and then Annmarie's littlest one has to go to the bathroom. Then we start to talk about up upcoming event just in time for CY's phone to ring. Then I start to pull out my calendar to go over a few odds and ends as CY packs up to take Jake to school and Annmarie gathers up her kids. Then I go in the family room to pick up the monopoly game that has been "played with" and is now on the floor.
I get a lot done at those meetings.
But my daughter Grace did start a wonderful scrapbook full of Moon Over Manifest pictures and memorabilia, Annmarie did design some great new business cards, along with some for herself and CY giving them each the job title of "Assistant to the Assistant." They are still waiting for their fully loaded credit cards but I do make sure they get coffee and an egg once a week.
We're all chipping in and we're all having a great time.
Hopefully, I'll get another update in before long. I need to go change a roll of toilet paper.
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The "Have I Got a Story For You" Trick
I'm no fan of bad, sloppy PR, and to me there's nothing quite as sloppy as pitching a product to a journalist s/he has already written about. Do these people not have any records at all? Do they have no idea of what coverage their product has already received?
I've been pitched two products in the past week that I have written about already in my WSJ.com column. OK, not everyone reads the WSJ, and not everyone reads the column, but it's not exactly a backwater publication that would have not shown up in someone's records, had they been keeping any.
First there was the Unotron washable keyboard, which I pretty much dedicated a whole column to a couple of years back (it shows up on the CollegeJournal with a search unotron wsj). In response to a request to the PR/expert source clearing house ProfNet a few days back I received a pitch from a PR guy which began
If you are looking for the latest technological advancement in computer keyboards, I may have your answer.
What surprised me here was that my column was copiously cited on the company's own website.
Then there's something called the Loc8tor, a tracking device I wrote about a few months back in another WSJ.com column. I just now received a pitch with the breathless subject line: "STORY IDEA: New RFID Tracking Device Finds Valuables with Directional Capabilities":
I am contacting you regarding a new product story that will help your readers stay organized and find their valuables.
The original column doesn't show up high in the search engines if you look for loc8tor wsj but a reference to it clearly shows up in a link to Peter Morville of findability.org, whom I interviewed for the piece. Seems the PR company could use the product themselves to keep track of previous coverage of their client's product.
(It's only "new", by the way, in the sense of newly available in the U.S.; the product's been around for at least a year in the UK and elsewhere. The PR person involved clearly doesn't have a particularly good database as my column has carried an Asian dateline for the past year, and my blog and webpage make clear I'm not U.S. based. Minor details, I grant you, but I feel sorry for the poor sap who's paying the agency if he's hoping for a well-targeted PR campaign.)
What's telling, to me, in both of these cases, is that I had originally dealt with the companies themselves, not with their PR companies. In fact, I'm not sure either had PR companies working with them when I dealt with them. In other words, these companies have hired PR companies to go get coverage, who then go undo the positive work the company itself had done by pitching to the self-same guys who have already given them coverage.
I can understand, I suppose, this kind of thing happening. But it's still sloppy, and clearly indicates that the PR company, when hired, does little or no research into what coverage the product has already received. Surely that would be the first thing you'd do, if only to see whether those publications or writers have already written about you might be worth cultivating for follow-up coverage down the track? At the very least, I guess I would assume you don't want to alienate those people by showing you have no idea what they've been writing about?
PR note #273: When you get a new client, Google them.
Comments (3)
I linked to this as another 'rule to remember' on my site as well.
This is an ongoing issue for journalists, companies and PR reps. On the PR side, it's more likely than not that, especially with younger companies, there has been little media coverage record keeping and new PR agencies and reps have to try to reconstruct who has been contacted and what the results were. Often, when a client is asked about prior outreach, they'll only remember a fraction of what was done.
So…then it's on to Google search, and searching individual media web sites. I've found this to be predictably incomplete, as is the case when searching WSJ.com for "loc8tor" — no results come up. So, I also use topix.net and icerocket.com — these two sites inevitably turn up media coverage that Google has missed (though, again, your first loc8tor story does not turn up.
But to your point that one would think a company would remember WSJ coverage; the answer is yes and no. I've had execs tell me of prior informal discussions with a WSJ, or NYT, or BWeek reporter, whose name they cannot remember "but I have their card somewhere." Or they have the right name, but incorrectly recall the newspaper or magazine of the reporter.
I'm not sure there is a true solution here. It's aggravating for both sides when a reporter is pitched a story they've already done. But the onus does fall on the companies and PR reps to do their research and record keeping. That's one of several reasons why, for every client I've ever had, I maintain a binder of all media coverage, and turn that over to the client at the end of every calendar year. It doesn't ensure they will remember who wrote about them, or that the next PR rep will utilize the older binders, but at least I set them up to have a record.
One of the finer examples of know-nothing PR work:


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text:
Gerard Butler Misses Carbs, Loves Jen Aniston As A Friend
Gerard Butler is no different than us. He hates dieting!
At the premiere of his new movie Law Abiding Citizen, the actor said that it wasn't easy getting prepared for his many shirtless scenes in the new action flick.
He complained to E! News,
"I wanna eat my potatoes and French fries and sponge cakes. When I play a role like this, I can't have my carbs and it makes me crazy."
He also dished on his rumored romance with Bounty costar Jennifer Aniston. They're totally just friends, he claims:
"I love her to death. She's the coolest and she's become a great friend, but there's nothing going on. And if there was, I'd be happy to say it!
Have your say in the comments section: Do you believe Gerard or do you think he's just trying to hide his new relationship with J. Aniston?


text:
Mirumoto Meisetsu was a bushi of the Dragon Clan.
Destroyer War Edit
In 1173 during the Destroyer War Meisetsu fought in the Battle of the River of Gold. He lacked the ability to find the flaws in the metallic caparaces of the Destroyers, diminishing to almost nothing the possibility he could take any kill on them. Suddenly the time seemed to stop for the others, and heard a voice in his mind, from the priestess Isawa Kumai. The shugenja had communed with the void reaching him to show Meisetsu where to strike the gaijin demons. The time recovered their normal pace and Meisetsu began to kill the Destroyers with his enhanced perception. [1]
External Links Edit
- Mirumoto Meisetsu (The Harbinger)
|This Dragon Clan related article is a stub. That means that it has been started, but is incomplete. You can help by adding to the information here.


text:
- Grant Scott
- 2 years ago
- Views:
1 Bioinformática Introducción, Bases de datos biológicas Prof. Mirko Zimic What is Bioinformatics? What is Bioinformatics? - Research, development, or application of computational tools and approaches for expanding the use of biological, medical, behavioral or health data, including those to acquire, store, organize, archive, analyze, or visualize such data. What is Computational Biology? - The development and application of dataanalytical and theoretical methods, mathematical modeling and computational simulation techniques to the study of biological, behavioral, and social systems. (Working Definition of Bioinformatics and Computational Biology - July 17, 2000). 1
2 The Ideal Syllabus Molecular Biology Basic concepts, Genomic and Proteomic structure Core Bioinformatics Biological Databases, Sequence Analysis, Functional Genomics Advanced Bioinformatics Molecular Evolution and Phylogeny Protein Structure Prediction The Transcriptome The Proteome Informatics Information Theory Basic Statistics Database Technologies Knowledge Representation Biocomputing Konrad Zuse con la Z1 reconstruída. Zurich 2
3 Durante la II Guerra mundial los ingleses construyen en respuesta al codificadorenigma, el Colossus. Enigma En 1944 IBM y la Universidad de Harvard estrenan Mark I, la primera computadora que responde a la moderna definición. Medía.15 metros de largo, 2.40 mts de alto y pesaba 10 toneladas. Utilizaba relays electromecánicos. 3
4 Este es uno de los relay que se usaron en la Mark I Sumaba en menos de un segundo, multiplicaba en cerca de seis, y dividía en cerca de doce. 4
5 Costo Efectividad! La Bioinformática resulta ser una disciplina muy favorable en cuanto a costo-efectividad. On Life... Living things are composed of lifeless molecules (Albert Lehninger) La Biología puede reducirse a las leyes Físicas fundamentales? 5
6 La Bioinformática se inicia con el desarrollo de bases de datos biológicas, seguido del desarrollo de herramientas de búsqueda rápida de información Actualmente la Bioinformática busca el desarrollo de algoritmos de predicción basado en la información almacenada en las bases de datos biológicas. 6
7 Historical Perspective Key developments: Dayhoff, Atlas of Protein Sequence and Structure ( ) Genbank/EMBL nucleic-acid sequence databases ( ) Entrez (early 90 s date) Sequence alignment algorithms: Needleman/Wunsch (1970), Smith/Waterman (1981), FASTA (Pearson/Lipman, 1988), BLAST (Altschul, 1990) Genomes (1995 date) Collecting Sequence Data Genome (DNA-level): Genomic sequencing Complete picture of genome Generates physical map Includes regulatory and other silent regions Transcriptome (RNA-level): Expression-library sequencing Expressed genes only Splicing / variant forms Can correlate with levels of expression Proteome (protein-level): Protein sequencing Insight into biological function Gives information on protein-protein interactions Post-translational modifications detected 7
8 DNA Sequencing DNA Sequencing (Cont d) 8
9 Fragment Assembly Genomic DNA Random shearing Sequence overlapping fragments Sequences assembled CCAGATTACGAAATCC... GGCTTATACCGGCAT Sequencing from Expression Libraries Exon 1 Exon 2 Exon 3 Exon 4 Exon 5 Gene Introns Transcription / splicing / processing AAA AAA mrna Reverse transcriptase AAA AAA TTT TTT Sequence Transcriptome 9
10 Secuenciamiento de Proteínas Digital Storage of Sequence Data Bit: A binary digit represented in a digital circuit; only two states recognized, 0 and 1 (usually 0 V and +5 V, respectively). Byte: Grouping of 8 bits into a larger unit. Bits are usually numbered 0-7 (not 1-8!). ASCII: Acronym for American Standard Code for Information Interchange. Representation of alphanumeric and some special characters as 1-byte (8 bit) unsigned integers { } (the set { }). The ASCII character set also includes nonprinting control characters such as carriage return (CR) or line feed (LF). Minimum storage requirement for human genome data represented as ASCII characters: bytes (3000 Mbytes) or about 5 CD-ROMs, exclusive of annotations or other data 10
11 11 Number Systems Number Systems F E D C B A Hex Octal Bin Dec Hex Octal Bin Dec The ASCII Table The ASCII Table
12 Extended ASCII Characters Nucleic-acid Base Codes Symbol Meaning Symbol Meaning A A S G or C G G W A or T C C H A, C, or T (~G) T T B C, G, or T (~A) R A or G V A, C, or G (~T) Y C or T D A, G, or T (~C) M A or C N A, C, G, or T K G or T Adapted from Mount, Bioinformatics Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (2001) 12
13 Amino-acid Codes 1-letter Code A C D E F G H I K L M 3-letter Code Ala Cys Asp Glu Phe Gly His Ile Lys Leu Met Amino Acid alanine cysteine aspartic acid glutamicacid phenylalanine glycine histidine isoleucine lysine leucine methionine 1-letter Code N P Q R S T V W X Y Z 3-letter Code Asn Pro Gln Arg Ser Thr Val Trp Xxx Tyr Glx Amino Acid asparagine proline glutamine arginine serine threonine valine tryptophan undetermined tyrosine Glu or Gln Adapted from Mount, Bioinformatics Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY (2001) The exponential growth of molecular sequence databases & cpu power Year BasePairs Sequences doubling time ~ one year 13
14 What are sequence databases? These databases are an organized way to store the tremendous amount of sequence information accumulating worldwide. Most have their own specific format. North America: the National Center for Biotechnology Information (NCBI), a division of the National Library of Medicine (NLM), at the National Institute of Health (NIH), has GenBank & GenPept. Europe: the European Molecular Biology Laboratory (EMBL), the European Bioinformatics Institute (EBI), and the Swiss Institute of Bioinformatics (SIB) Expert Protein Analysis System (ExPasy), all help maintain the EMBL Nucleotide Sequence Database, and the SWISS- PROT & TrEMBL amino acid sequence databases. Asia: The National Institute of Genetics (NIG) supports the Center for Information Biology s (CIG) DNA Data Bank of Japan (DDBJ). More organization stuff Nucleic acid sequence databases (and TrEMBL) are split into subdivisions based on taxonomy (historical rankings the Fungi warning!). PIR is split into subdivisions based on level of annotation. TrEMBL sequences are merged into SWISS-PROT as they receive increased levels of annotation. Nucleic Acid DB s GenBank/EMBL/DDBJ all Taxonomic categories Tags EST s GSS s Amino Acid DB s SWISS-PROT TrEMBL PIR PIR1 PIR2 PIR3 PIR4 NRL_3D Genpept 14
15 TrEMBL contains the translations of all coding sequences (CDS) present in the EMBL Nucleotide Sequence Database, which are not yet integrated into SwissProt. PIR (Protein Information Resource) produces the Protein Sequence Database (PSD) of functionally annotated protein sequences, which grew out of the Atlas of Protein Sequence and Structure ( ) edited by Margaret Dayhoff TREMBL (proteina traducida del EMBL) EMBL (DNA) SwissProt (proteínas secuenciadas curadas) PIR PROSITE GeneBank DDBJ 15
16 What about other types of biological databases? Three dimensional structure databases: the Protein Data Bank and Rutgers Nucleic Acid Database. These databases contain all of the 3D atomic coordinate data necessary to define the tertiary shape of a particular biological molecule. The data is usually experimentally derived, either by X-ray crystallography or with NMR, but sometimes it is a hypothetical model. In all cases the source of the structure and its resolution is clearly indicated. Secondary structure boundaries, sequence data, and reference information are often associated with the coordinate data, but it is the 3D data that really matters, not the annotation. Other types of Biological DB s Still more; these can be considered non-molecular : Genomic linkage mapping databases for most large genome projects(w/ pointers to sequences) H. sapiens, Mus, Drosophila, C. elegans, Saccharomyces, Arabidopsis, E. coli,.... Reference Databases (also w/ pointers to sequences): e.g. OMIM Online Mendelian Inheritance in Man PubMed/MedLine over 11 million citations from more than 4 thousand bio/medical scientific journals. Phylogenetic Tree Databases: e.g. the Tree of Life. Metabolic Pathway Databases: e.g. WIT (What Is There) and Japan s GenomeNet KEGG (the Kyoto Encyclopedia of Genes and Genomes). Population studies data which strains, where, etc. And then databases that many biocomputing people don t even usually consider: e.g. GIS/GPS/remote sensing data, medical records, census counts, mortality and birth rates
17 Large Databases Once upon a time, GenBank sent out sequence updates on CD-ROM disks a few times per year. Now GenBank is over 40 Gigabytes (11 billion bases) Most biocomputing sites update their copy of GenBank every day over the internet. Scientists access GenBank directly over the Web Finding Genes in GenBank These billions of G, A, T, and C letters would be almost useless without descriptions of what genes they contain, the organisms they come from, etc. All of this information is contained in the "annotation" part of each sequence record. 17
18 Entrez is a Tool for Finding Sequences GenBank is managed by the NCBI (National Center for Biotechnology Information) which is a part of the US National Library of Medicine. NCBI has created a Web-based tool called Entrez for finding sequences in GenBank. Each sequence in GenBank has a unique accession number. Entrez can also search for keywords such as gene names, protein names, and the names of orgainisms or biological functions 18
19 Entrez is Internally Cross-linked DNA and protein sequences are linked to other similar sequences Medline citations are linked to other citations that contain similar keywords 3-D structures are linked to similar structures 19
20 Databases contain more than just DNA & protein sequences The omics Series Genomics Gene identification & charaterisation Transcriptomics Expression profiles of mrna Proteomics functions & interactions of proteins Structural Genomics Large scale structure determination Cellinomics Metabolic Pathways Cell-cell interactions Pharmacogenomics Genome-based drug design 20
21 Structural Genomics What is structural genomics? Genomes and folds: Finding folds in genomes Structural properties of entire proteomes Comparing genomes in terms ofstructure Selectionof targets for structuralgenomes Covering the sequence space withstructures Using structure to understand function Systematic structure determination for complete genomes Special targets Predicting success of structure determination Adaptationof proteins to extreme environments Structural genomics resources on the internet Functional Genomics Development and application of global (genome-wide or system-wide) experimental approaches to assess gene function by making use of the information provided by structural genomics. 21
22 Commercial Structural Genomics Initiatives IBM (Blue Gene project: 2000) Computational protein folding Geneformatics (1999) Modeling for identifying active sites Prospect Genomics (1999) Homology modeling Protein Pathways (1999) Phylogenetic profiling, domain analysis, expression profiling Structural Bioinformatics Inc (1996) Homology modeling, docking Proyecto Genoma Humano La secuencia del genomaestá casicompleta! aproximadamente 3.5 billones de pares de bases. 22
23 Raw Genome Data Implications for Biomedicine Physicians will use genetic information to diagnose and treat disease. Virtually all medical conditions (other than trauma) have a genetic component. Faster drug development research Individualized drugs Gene therapy All Biologists will use gene sequence information in their daily work 23
24 Bioinformatics Challenges The huge dataset Lots of new sequences being added - automated sequencers - Human Genome Project - EST sequencing GenBank has over 10 Billion bases and is doubling every year!! (problem of exponential growth...) How can computers keep up? 24
25 Genome comparisons Designed for looking at complete bacterial genomes. Gene finding AT content Forward translations Reverse Translations DNA and amino acids 25
26 Gene finding Bringing a New Drug to Market Review and approval by Food & Drug Administration Phase III: Confirms effectiveness and monitors adverse reactions from long-term use in 1,000 to 5,000 patient volunteers. 1 compound approved Phase II: Assesses effectiveness and looks for side effects in 100 to 500 patient volunteers. Phase I: Evaluates safety and dosage in 20 to 100 healthy human volunteers. 5 compounds enter clinical trials 5,000 compounds evaluated Discovery and preclininal testing: Compounds are identified and evaluated in laboratory and animal studies for safety, biological activity, and formulation Years 16 26
27 Impact of Structural Genomics on Drug Discovery Epitopes B-cell epitopes T h -cell epitopes 27
28 Vaccine development In Post-genomic era: Reverse Vaccinology Approach. How a molecule changes during MD 28
29 In Silico Analysis Peptide Multitope vaccines VACCINOME Candidate Epitope DB Epitope prediction Disease related protein DB Gene/Protein Sequence Database The job of the biologist is changing As more biological information becomes available The biologist will spend more time using computers The biologist will spend more time on data analysis (and less doing lab biochemistry) Biology will become a more quantitative science (think how the periodic table and atomic theory affected chemistry) 29
30 Biological Research in 21st Century The new paradigm, now emerging is that all the 'genes' will be known (in the sense of being resident in databases available electronically), and that the starting point of a biological investigation will be theoretical. - Walter Gilbert 30
31 Data Quality Issues Bioinformatics Databases Usually organised in flat files Huge collection of Data Include alpha-numeric and pictorial data Latest databases have gene/protein expression data (images) Demand High quality curated data Interconnectivity between data sets Fast and accurate data retrieval tools queries using fussy logic Excellent Data mining tools For sequence and structural patters 31
32 Errors in DNA sequence and Data Annotation Current technology should reduce error rates to as low as 1 base in as every base is sequenced between 6-10 times and at least one reading per strand. Therefore, in a procaryote, error of 1 isolated wrong base would result to one amino acid error in ~10-15 proteins. In human genome gene-dense regions contain about 1 gene per bases, with average estimated at 1 gene per 30000bases. Therefore, corresponding error rate would be roughly one amino acid substitution in 100 proteins. But large scale error in sequence assembly can also occur. Missing a nucleotide can cause a frameshift error. DNA data The DNA databases (EMBL/ GenBank/ DDBJ) carry out quality checks on every sequence submitted. No general quality control algorithm is yet in widespread use. Some annotations are hypothetical because they are inferences derived from the sequences. Ex. Identification of coding regions. These inferences have error rates of their own. 32
33 Quality Control Issues related to 3-D structure data determined using X-rays The reported parameter called the `B-factor' of each atom describes its effective size, and for proteins it should be treated as an empirical value. Because every atom contributes to every observation, it is difficult to estimate errors in individual atomic positions. Resolution of structures in PDB Low resolution... High Resolution in Å Ratio of observations to Parameters The median resolution of structures in the Protein Data Bank is about 2.0 Å. 33
34 Un ejemplo Cisteíno proteasa de la fasciola hepática: En busca de un péptido inmunogénico Alineamiento: cisteíno proteasas de mamífero Vs. cisteíno proteasa de Fasciola hepatica. AA Idénticos AA divergentes VPKSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGR ISLSEQNLVDCSRPQGN AVPDKIDWRESGYVTEVKDQGNCGSCWAFSTTGTMEGQYM KNERTSISFSEQQLVDCSRPWGN ROJO QGCNGGLMDNAFQYIKENGGLDSEESYPYEATDTSCNY KPEYSVANDTGFVDIPQREKA LMK NGCGGGLMENAYQYLKQF GLETESSYPYTAVGGQCRYNKQLG VAKVTGYYTV QSGSEVEL KN _VIOLETA AMARILLO AVATVGPISVAIDAGHSFQFYKSGIYYEPDCSSKDLDHGVLVVGYGFEG TDSNNNKYW IVKNSW LIGSEGPSAVAVDVESDFMMYRSGIYQSQTCSPLRVNHAVLAVGYGTQGGTD YW IVKNSW VERDE GPEWGM-GYVKMAKDRNNH CGIATAASYPTV GLSWGERGYIRMV RNRGNMCGIASLASLPMVARFP 34
35 Epítope Discontinuo, formado por porciones distantes de la secuencia. Denaturación El epítope se pierde con la denaturación. Epítope Continuo, formado por una porción de la secuencia Denaturación El epítope se conserva como tal. 35
36 Modelaje tridimensional por homología. Identidad de secuencia de 56% con quimopapaína (1YAL) Análisis de Superficie:vista de átomos por radio de van der Waals AA idénticos AA divergentes 36
37 Selección de secuencias (1)divergentes, (2)accesibles al solvente y (3)contínuas. TMEGQYMKNERTSISFS YYTVQSGSEVELK NLIGSE QSQTCSPLRVN RYNKQLGVAKV Otro ejemplo Sensibilidad de la aspartyl proteasa del HIV-1 a los inhibidores más frecuentes 37
38 Representación en cartoon de la enzima proteasa de HIV-1 Enzima proteasa de HIV-1 mostrando los elementos de estructura secundaria, flaps y sitio activo 38
39 Enzima proteasa de HIV-1 indicando los residuos consenso de unión inhibidor-enzima INDINAVIR 39
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text:
I am moving to Seattle to start an exciting new job (stay tuned for details).
My last day in New York will be Sunday 19 March. I have loved living here for the past three and a half years, and I'm certain that I'll miss it dearly. New York is a special place, and I consider myself very privileged to have lived here twice, as a college student from 1999 to 2003 and then again as an adult from 2013 to 2017.
Old apartment
My apartment is available, by the way. I've posted information about it on Facebook and Craigslist.
It's important to me that a new tenant sign a lease and move into the apartment ASAP, because I have to continue paying rent until that happens (plus a $500 fee to terminate my lease early, plus I have to continue paying the difference if someone rents it for less than I was paying). If you know anybody who might like an insanely large one bedroom apartment in a fantastic neighborhood, please share the posts above with him or her!
New neighborhood
My new neighborhood in Seattle is called Belltown. I'll be pretty close to the Pike Place Market, and to the waterfront, and to the Space Needle, so I anticipate many long walks with Sharav and many photographs of Puget Sound.
I hope that you'll consider visiting me in Seattle, or at least that you'll let me know when you're coming to the area for some other purpose. I know almost nobody in the Pacific Northwest, so it would be great to see some familiar faces.
Whether you visit or not, would you consider sending me a postcard from wherever you are in the world? My new address is on my Facebook, but if you don't use Facebook, just fill out the form below to get in touch and I'll email it to you.
Also, please be sure to leave me your address, so I can send you a postcard!


text:
Hi there,
I have a strange problem with the NETWORK MAP view
I am using the latest Beta version and everything seems to be fine except the MAP. Why I am having an overlaping in the MAP?
I tried to uninstall, clear the cache, reinstall but still same issue.
Thanks for your tremendious effort.
3 Replies
· · ·
Nov 10, 2009 at 2:15 UTC
akp982 is an IT service provider.
- Are you running the latest version of Spiceworks?
- Have you seen http:/
/ community.spiceworks.com/ help/ Network_Map_Overview#Stack
- Do you have snmp enabled switches?
· · ·
Nov 10, 2009 at 4:46 UTC
I am running Version 4.5.42292, I just saw that there is a new beta version. I will try and see how it goes.
The switches are SNMP enabled.
· · ·
Nov 10, 2009 at 7:19 UTC
It looks much better with the latest Beta version . I can see all the topology now.


text:
There's a new beetle in town, and its name is Duvalius Abyssimus, a resident in good standing of the planet's deepest known cave.
Researchers from two universities in Spain announced in the journal Zootaxa that they had collected two specimens -- a male and a female -- of the new beetle living deep in Krubera cave, in Russia's Western Caucasus.
The Krubera is deeper than any cave we know about, spanning more than 7,000 feet between its entrance and its deepest known point. Just reaching its greatest explored depth requires diving skills to get past flooded underground chambers.
VIDEO: Bugs, Arthropods, and Insects! Oh My!
As for the new beetle, it's certainly in the right family tree for cave-dwelling. Most species in its Duvalius genus are experienced in the subterranean ways.
But this newest genus member doesn't have all of the accouterments of the super-serious grotto resident. That's because it has something many highly specialized deep-cave dwellers don't: eyes.
The new species was found by researchers Ana Sofía Reboleira, from the Universities of Aveiro and La Laguna, and Vicente M. Ortuño, from the University of Alcalá.
"The discovery of the new beetle provides important data on species that co-exist in these almost unknown ecosystems, even more so when they are found in a geographical area that is very difficult to access," said Ortuño. "Such is the case with this cave."
Duvalius Abyssimus
Ticks resemble little bumps on skin, but a closer look reveals the barbed mouthpart (hypostome) that's inserted in human flesh and can't easily slip out. Dania Richter of the Technical University of Braunschweig watched, under very high magnification, ticks using other mouthparts to pierce skin, generating "a toehold," before a breaststroke-like action pulled in the barbed hypostome. The study is published in the latest Proceedings of the Royal Society B.
This scanning electron micrograph image of a southern house mosquito (foreground) makes evident the straw-like mouthpart used to suck human -- and other -- blood. The red and black additions highlight smelling activity. It's believed that a mosquito can smell a person from 100 feet away.
Spiders in the genus Loxosceles, including the brown recluse, are among the few common spiders whose bites can seriously hurt people. Greta Binford, an associate professor of biology at Lewis and Clark College, recently studied the spiders, including the one shown here from South America. The spider bites can cause our skin to die. "Our bodies are basically committing tissue suicide," she explained. "That can be very minor to pretty major, like losing a big chunk of skin. The only treatment in that case is usually to have a skin graft done by a plastic surgeon."
Older workers within a rainforest termite species,
Neocapritermes taracua
, have built-in "explosive backpacks" that become bigger and more deadly over time. The blue in this image -- showing several workers and a soldier termite -- is actually a sack of toxic blue liquid. Jan Šobotnik at Academy of Sciences of the Czech Republic in Prague found that worker termites could explode this toxin onto enemies during suicide missions that help their colonies.
Entomologist Michael Caterina and his team studied clown beetles, which munch on fly larvae found in decomposing bodies He snapped this shot, which shows one such beetle's mandibles. It's apparently a bug-eat-bug world, even in the remains of the deceased.
Slimy slugs are the bane of gardeners, but a recently discovered slug species makes others seem tame. The 'ghost slug,' found in Cardiff, Wales, lives on land, is carnivorous and possesses blade-like teeth. It's out all year round -- not just on Halloween.
This fly was photographed after it became stuck in a glob of hand sanitizer, so it was likely frozen in this image seconds before its demise. The photo reveals the fly's compound eyes, which have the fastest visual responses in the animal kingdom. The tongue-like proboscis is also sticking out.
Leeches are predominantly bloodsuckers that feed on blood from humans and other animals. When leeches bite into a victim, their saliva prevents blood from clotting, causing victims to bleed from the wound for hours. The good news is that this effect has beneficial microsurgery applications, such as helping doctors reattach tiny veins.
The zombie-ant fungus invades an ant's brain, causing the insect to march to its death at a mass grave near the ant colony. The fungus winds up the winner, since it then erupts via spores that come out of the ant's head. A parasitic fungus, however -- the white and yellow material in this image -- can castrate the zombie-ant fungus, allowing the ant to live.
Photographer Linda Tanner spotted this black widow spider in an old, dark barn, heading for a front porch. Black widows are very common, and are often found in garage door slats, hiding in dark corners, under woodpiles and in other places in and around homes. Usually they mind their own business, focusing on their insect prey, but their venom can cause human victims to experience nausea, muscle aches and paralysis of the diaphragm, which can lead to breathing difficulties.


text:
- Player HQ — Track Call of Duty: Black Ops II performance with rich game statistics, including enhanced match information such as heat maps and recent match data; track challenges and extensively modify your classes like never before using Treyarch's new Pick 10 Create-a-Class system.
- Clan HQ — Join an existing clan or start your own, invite friends and then take part in Call of Duty: Black Ops II clan competitions with cool digital prizing.
- Zombies Support — For the millions of Zombies fans out there, now you can track your Zombies personal statistics and compare it to other players' around the world.
- Call of Duty Elite TV — Launching with tablet support with Call of Duty: Black Ops II, the new Call of Duty Elite TV will deliver a renewed community focus featuring developer tips and strategy programming, custom class overviews and more.
- Social Sharing and Notifications — With Call of Duty Elite's new notification system, you can stay updated with what is going on in Call of Duty: Black Ops II, as well as communicate directly with your clan.
Today Activision announced its ELITE intergration in Call of Duty: Black Ops II. It will be completely free for everyone and all users will get the same range of content from it.
Eric Hirshberg, Activision Publishing CEO, said that ""We've learned a lot in our first year of Call of Duty Elite, and we're very proud that we over delivered on our commitment of playable content to our premium members. What we have realized is that several of the Call of Duty Elite services which are currently only available to our premium members for Call of Duty: Modern Warfare 3 are things that would further unite, engage and delight our player community. So we are going to make them free for Call of Duty: Black Ops II."
Instead of premium ELITE services there is set to be a season pass for the game. 4 DLC packs, which include Multiplayer Maps and Zombie maps, will appear some time in 2013 at a cost of $15 each. However the season pass will cost $50 meaning you will save $10. Preorders for the Season Pass go on sale at retailers today but DLC content won't start appearing until some time in 2013.
Thanks to CharlieINTEL, OneofSwords and Shadowking58 for this information.