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Construction of the first genetic linkage map of Japanese gentian (Gentianaceae)
Plant genomics
Japanese gentians (
Enriched simple sequence repeat (SSR) libraries from a
This is the first reported genetic linkage map for Japanese gentians and for any species belonging to the family Gentianaceae. As demonstrated by mapping of functional markers and the stem color trait, our results will help to explain the genetic basis of agronomic important traits, and will be useful for marker-assisted selection in gentian breeding programs. Our map will also be an important resource for further genetic analyses such as mapping of quantitative trait loci and map-based cloning of genes in this species.
Gentianaceae (order Gentianales), comprises 87 genera and more than 1,500 species that are distributed worldwide. The genus
There has been extensive molecular and physiological research on flower colors, flowering times, and cold tolerance of winter buds of Japanese gentians
Genetic linkage maps are useful for studies on genomic structure and evolution, and for identification of monogenic traits or Mendelian components of quantitative trait loci (QTLs). Therefore, they are very useful for breeding programs and are the basis for future positional gene cloning
The majority of floricultural plants are allogamous, but most linkage maps for crop plants have been obtained from segregating populations derived from crosses between inbred lines. Therefore, genetic linkage maps for allogamous and vegetatively reproducing species have been constructed using a double pseudo testcross strategy
Here, we report the construction of a genetic linkage map for Japanese gentian,
Simple sequence repeat markers
The enriched SSR libraries from the DH line Aki6PS (
We screened 1,229 SSR markers using both parents and one F1 individual. Most SSR markers showed no or unstable amplification, or produced amplified fragments with unexpected lengths. Eighty SSR markers detected significant polymorphisms as co-dominant markers. In addition, 21 SSR markers were dominant markers, amplifying PCR fragments from SP6A1 and F1 but not from Aki6PS (Table
Retrotransposon microsatellite amplified polymorphism markers
To increase the number of available genetic markers for Japanese gentian, we developed some retrotransposon microsatellite amplified polymorphism (REMAP markers) using a retrotransposon. A retrotransposable element
Figure 1
Schemes of iPBS and REMAP.
Schemes of iPBS and REMAP. A) iPBS is an efficient method which isolates long terminal repeat (LTR) sequences of retrotransposons
Amplified fragment length polymorphism markers
Our preliminary experiments showed that conventional amplified fragment length polymorphism (AFLP) amplification using combinations of selective primers with three selective nucleotides resulted in too many faint and overlapping fragments in gentian (data not shown). To solve this problem, we added a fourth selective nucleotide to the
Long random amplification polymorphic DNA markers
We first screened for reproducible and stable random amplification polymorphic DNA (RAPD) markers using 47 primers, as described by Debener and Mattiesch
Functional markers
In Japanese gentians, there has been extensive physiological and molecular research on flower pigmentation, flowering time, and cold tolerance of winter buds, and the nucleotide sequences of some important genes have already been deposited in public databases. In addition, our previous study reported significant insertions/deletions (in/dels) in introns and untranslated regions, representing molecular polymorphisms that could be used to discriminate among cultivars and species of Japanese gentians
Segregation of stem pigmentation trait
Genetic map construction
We used a population of 93 BC1 from
Figure 2
Production of BC1 progeny for genetic linkage analysis.
Production of BC1 progeny for genetic linkage analysis.
Figure 3
Genetic linkage map of
Genetic linkage map of
We used 454 FLX Titanium pyrosequencing of an SSR-enriched library to develop SSR markers from Japanese gentians. Recently, next generation sequencing has been used successfully to develop several genetic markers, including SSRs
Retrotransposons can be used as molecular markers because their integration creates new junctions between genomic DNA and their conserved ends
RAPD and AFLP technologies are conventional molecular markers. Their advantages are that they do not require sequence information and have a relatively low start-up cost
A genetic linkage map with 273 markers was constructed using an interspecific BC1 population. Nineteen linkage groups were obtained for the BC1 population at an LOD value of 9.0, and encompassed 613.7 cM (Figure
In the BC1 progeny of Japanese gentians, 30.0% of markers showed segregation distortion. These skewed segregations were also reported in other ornamental plants species, such as the diploid rose
Functional markers are those derived from polymorphic sites within genes responsible for phenotype traits
This study presents the first genetic linkage map for Japanese gentian. The map was constructed using four different types of molecular markers. It was produced from genotypes of 93 BC1 progeny derived from a DH line and included 274 markers (97 SSR, 97 AFLP, 39 RAPD, 30 REMAP, 10 functional markers, and 1 phenotypic trait). The map revealed 19 linkage groups that covered 613.7 cM, with an average intermarker distance of 2.2 cM. This map is a starting point for mapping single or quantitative trait loci affecting agronomically important phenotypes, and will be useful for research on gentian genetics and breeding.
Plant Materials
In total, 93 BC1 progeny were derived from the interspecific backcross Aki6PS×SP6A1 (Figure
Genomic DNA was isolated from young leaves (500 mg) of each individual using Nucleon PhytoPure (GE Healthcare, Little Chalfont, UK) and stored at −20°C until use.
Simple sequence repeat markers
SSR markers were developed as described by Sato-Ushiku et al.
PCR amplification was performed in a 20-μL reaction mixture containing 10 ng genomic DNA, 0.5 μM each primer (Table
Retrotransposon microsatellite amplified polymorphism markers
The sequences of LTRs of retrotransposons were isolated from gentian genome using the iPBS approach
The REMAP markers were created by combining LTR primers with ISSR primers, as shown in Table
Amplified fragment length polymorphism markers
AFLP analysis was performed as described by Vos et al.
Pre-amplification was conducted in a 25-μl reaction volume containing 2.5 μl diluted adaptor-ligated DNA, 0.4 μM EcoRI+A primer, 1.6μM MseI+C primer, 200 μM dNTPs, 1×
Long random amplified polymorphic DNA markers
The long RAPD markers were developed as described by Debener and Mattiesch
Functional markers
Our previous research revealed that the intron lengths of several flavonoid biosynthetic genes, including
PCR amplification was performed in a 20-μL reaction mixture containing 20 ng genomic DNA, 0.5 μM each primer (as shown in Table
Evaluation of stem pigmentation
Stem colors were investigated three times in the mapping population. Green and red stem colors were scored as
Linkage analysis
We used 308 markers, including 101 SSRs, 38 REMAPs, 103 AFLPs, 54 long RAPDs, 11 functional markers, and one phenotypic trait to construct a genetic linkage map using JoinMap ver. 4.1 (Kyazma, Wageningen, Netherlands). The Kosambi function was used to convert recombination units into genetic distances. The mapping analysis was conducted by using a minimum LOD score of 9.0. Distorted markers analyzed by the chi-square test were used in the construction of the linkage maps.
AFLP: Amplified fragment length polymorphism; ANS: Anthocyanidin synthase; bHLH: Basic helix-loop-helix; CAPS: Cleaved amplified polymorphic sequence; CHS: Chalcone synthase; CHI: Chalcone isomerase; DH: Doubled haploid; F3′5′H: Flavonoid 3′,5′-hydroxylase; FHT: Flavanone 3-hydroxylase; FT: Flowering locus T; ISSR: Inter-simple sequence repeat; LTR: Long terminal repeat; MITE: Miniature inverted-repeat in transposable element; PBS: Primer binding site; QTL: Quantitative trait loci; RAPD: Random amplification polymorphic DNA; REMAP: Retrotransposon microsatellite amplified polymorphism; SCAR: Sequence characterized amplified region; SSR: Simple sequence repeat; TDR: Terminal direct repeat; TFL1: Terminal flowering 1; TRIM: Terminal repeat retrotransposon in miniature.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
TN participated in the design of the experiments, and developed and genotyped the SSR, AFLP and functional markers, performed statistical analysis, data interpretation and wrote the paper. EY developed and genotyped the RAPD and REMAP markers. TH participated in the design of the experiments and produced populations for genetic analysis. MS developed and genotyped the SSR and AFLP markers. YU developed the SSR markers. MN participated in the design of the experiments and wrote the paper. All the authors read and approved the manuscript.
The authors are especially grateful to Drs. Toshiya Yamamoto and Miyuki Kunihisa, National Institute of Fruit Tree Science (NIFTS), and Drs. Masafumi Yagi and Takashi Onozaki, National Institute of Floricultural Science (NIFS), for helpful discussions and technical advice. We thank Dr. Masumi Yamagishi, Hokkaido University, for providing long RAPD primers and technical advice. We thank Drs. Tomohiro Imamura and Hideyuki Takahashi, Iwate Biotechnology Research Center, for providing sequence information for flowering time genes and for helpful discussions. The authors thank Drs. Hisako Doi and Yoshihito Takahata, Iwate University, for providing the double haploid gentian line Aki6PS. We thank Dr. Hiroyuki Fukuoka, National Institute of Vegetable and Tea Science (NIVTS), for technical advice on developing SSR markers. The authors thank Mses. Chiharu Yoshida and Yoshiko Abe, members of our laboratory, for technical support. This study was supported by a 'Research Project for Utilizing Advanced Technologies in Agriculture, Forestry and Fisheries' from the Ministry of Agriculture, Forestry and Fisheries of Japan (MAFF), and by the Japan Science and Technology Agency (JST).
Gentians: From gene cloning to molecular breeding
Phylogenetic affinity of Mycochaetophora gentianae, the causal fungus of brown leaf spot on gentian (Gentiana triflora), to Pseudocercosporella-like hyphomycetes in Helotiales
Pathogenicity of Mycochaetophora gentianae, causal fungus of gentian brown leaf spot, as affected by host species, inoculum density, temperature, leaf wetness duration, and leaf position
Genetic relationships in the genus Gentiana based on chloroplast DNA sequence data and nuclear DNA content
Analysis of the genome sequence of the flowering plant Arabidopsis thaliana
The Medicago genome provides insight into the evolution of rhizobial symbioses
The map-based sequence of the rice genome
The tomato genome sequence provides insights into fleshy fruit evolution
Temporal expression of flavonoid biosynthesis-related genes regulates flower pigmentation in gentian plants
Identification and characterization of R2R3-MYB and bHLH transcription factors regulating anthocyanin biosynthesis in gentian flowers
The gentian orthologs of the FT/TFL1 gene family control floral initiation in Gentiana
Structure and allele-specific expression variation of novel alpha/beta hydrolase fold proteins in gentian plants
W14/15 esterase gene haplotype can be a genetic landmark of cultivars and species of the genus Gentiana L
Development of codominant DNA marker distinguishing pink from blue flowers in Gentiana scabra
Development of DNA markers that discriminate between white- and blue-flowers in Japanese gentian plants
Identification of gentian cultivars using SCAR markers based on intron-length polymorphisms of flavonoid biosynthetic genes
Development of simple sequence repeat markers for identification of Japanese gentian cultivars
Marker-assisted selection: new tools and strategies
Markers and mapping revisited: finding your gene
Construction of a genetic linkage map for roses using RAPD and AFLP markers.
Construction of an integrated map of rose with AFLP, SSR, PK, RGA, RFLP, SCAR and morphological markers
Construction of genetic linkage map for the carnation by using RAPD and SSR marker and mapping quantitative trait loci (QTL) for resistance to bacterial wilt caused by Burkholderia caryophylli
QTL analysis for resistance to bacterial wilt (Burkholderia caryophylli) in carnation (Dianthus caryophyllus) using an SSR-based genetic linkage map
Genetic analysis of floral anthocyanin pigmentation traits in Asiatic hybrid lily using molecular linkage maps
Development of SSR and gene-targeted markers for construction of a framework linkage map of Catharanthus roseus
Genetic linkage maps of Eucalyptus grandis and Eucalyptus urophylla using a pseudo-testcross: Mapping strategy and RAPD markers
A high-density molecular map for ryegrass (Lolium perenne) using AFLP markers
An SSR-based genetic linkage map for perennial ryegrass ( Lolium perenne L.)
Embryogenesis and doubled haploid production from anther culture in gentian (Gentiana triflora)
Two different transposable elements inserted in flavonoid 3',5'-hydroxylase gene contribute to pink flower coloration in Gentiana scabra
iPBS: a universal method for DNA fingerprinting and retrotransposon isolation
Construction of an AFLP genetic map with nearly complete genome coverage in Pinus taeda
PCR-based molecular markers in Asiatic hybrid lily
Genome-wide genetic marker discovery and genotyping using next-generation sequencing
Microsatellite discovery by deep sequencing of enriched genomic libraries
Representativeness of microsatellite distributions in genomes, as revealed by 454 GS-FLX titanium pyrosequencing
IRAP and REMAP for retrotransposon-based genotyping and fingerprinting
IRAP and REMAP: two new retrotransposon-based DNA fingerprinting techniques
A single-base substitution suppresses flower color mutation caused by a novel miniature inverted-repeat transposable element in gentian
AFLP: a new technique for DNA fingerprinting
AFLP technology for DNA fingerprinting
Long primers for RAPD mapping and fingerprinting of grape and pear
An integrated high-density RFLP-AFLP map of tomato based on two Lycopersicon esculentum × L. pennellii F2 populations
A consensus linkage map for molecular markers and quantitative trait loci associated with economically important traits in melon (Cucumis melo L.)
A high-density, integrated genetic linkage map of lettuce (Lactuca spp.)
Analysis of complex leaf and flower characters in Rhododendron using a molecular linkage map
Functional markers in plants
Two different mutations are involved in the formation of white-flowered gentian plants
read2Marker: a data processing tool for microsatellite marker development from a large data set
Genome analysis of Lotus japonicus
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs


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Firm DescriptionSince I started the studio in 2001 I have combined my practice with a teaching activity at the Royal Academy of Fine Arts, School of Architecture. This has led to a very enriching and challenging time in which the academic experience has influenced the way I have developed my professional practice and the way I approach architecture.
My international background, my knowledge to some extend objective approach to the Danish culture, and not least my interest and understanding of the Nordic tradition in architecture, has contributed positively on the understanding the aspects of culture in architecture. In my projects as a marriage between Nordic simple lines and a southern comprehension of space and movement, and in the school by organizing international workshops where to discuss these cultural aspects.

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Release Notes: This version includes many small bugfixes and implementations of small features, marking a stable point in development before some more major changes planned for the next version.
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This is just what I wanted. It has the power of mozilla but is easy to use with the keyboard. Nice!
A Fluent OpenStack client API for Java.
A TWiki appliance that is easy to use and lightweight.


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Raft in the longest river of Nepal originated at Kailash, the holiest mountain of Hindus.
Karnali river rafting is one of world's best rafting trips available in Nepal. The river originated from the Holiest Mountain of Hindus, "Mt. Kailash" in Tibet, ends at the Ganges in India. The river lodged through the mountains, hills, humid forests is rich in wild lives including the Catfish. Natural and traditional lifestyle as settled in the environs of the raft route makes it a fantastic journey.
Day 01 Drive Kathmandu to Dungeswor (1300m)
Day 02 Start Rafting in Karnali
Day 03 Rafting. Camp at Junglaghat (2804m, ¾ hours)
Day 04 Rafting. Camp by riverside (2600m,3 hours)
Day 05 Raft continuous in Karnali. Camp (3440m, 5 hours)
Day 06 Explore the Canyon, rafting and camp
Day 07 Raft through the jungle. Camping beside Jungle (3860m, 6 hours)
Day 08 Continue rafting through the village (4400m, 4 hours)
Day 09 End the rafting and rest
Day 10 Drive to Kathmandu
Day 11 Departure (4900m, 5 hours)


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Beautiful and charming two story home in gated community built in 2006. Good lay out kitchen. Huge master bedroom and bath. Good size backyard with open patio for entertaining or playground. Immaculate condition and ready to move in. Close to UC Riverside and downtown district. Lease includes refrigerator, washer/ dryer, gas stove & oven, gardener and HOA. COMMUNITY SWIMMING POOL . Please fax credit report with any application. Call agent for details. To open gate: press "key" sign twice then "2266"
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|Home -> News -> Report
|Entire Indian team will tour Pakistan: Ganguly
Wednesday, February 18 2004 20:24 Hrs (IST)
"We are still concerned about security, but the Government is looking after it. We hope there will be tight security," Ganguly said adding, "everybody will be going".
"All the team members are physically and mentally fit," Ganguly told reporters at the state secretariat where he had gone to meet Chief Minister Buddhadev Bhattacharjee to discuss the setting up of a cricket academy in the metropolis.
He said the entire team would be going to Pakistan with the exception being Harbhajan Singh, who is yet to recover completely from a finger injury. When the Indian skipper's attention was drawn to the Board of Control for Cricket in India (BCCI) stand that no player will be forced to go on the tour he said, "this is normal procedure and happens before every tour."
Ganguly, however, said that he was not aware of the report of the three-member BCCI team, which recently toured Pakistan to assess the security arrangements at all the venues.
Ganguly expressed confidence that the Indian team would return victorious from Pakistan in view of its recent performance in Australia.
"We played very well in the series against Australia. Considering the fact that Australia is the world's number one team, even if we play 60 per cent of our game, we will win the Pakistan series," Ganguly said.
The Indian team is scheduled to leave for Pakistan in the first week of March. The BCCI was expected to announce the itinerary of the series later this week.
Ganguly discussed with the Chief Minister the details of his proposed cricket academy in the metropolis for which the state Government will provide the infrastructure. Ganguly also handed over a cheque of over Rs 70 lakh to the Chief Minister which he had raised opening a paediatric care intensive unit at the Dr B C Roy Memorial Hospital for Children.
Zaheer, Nehra recover well ahead of Pak tour
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BEO Manoj Srivastav was arrested yesterday after a teacher at a government primary school in Pisawa alleged that she was called at the residence by the officer, where he tried to molest here.
An FIR has been registered in the matter and the officer was arrested. A report will be filed before the state government in this regard, Basic Siksha Officer (BSA) Sanjay Shukla said.


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Here's a fact that you didn't hear at the confirmation hearings for John Brennan, President Barack Obama's pick for CIA chief, or from the administration's white paper on drone killings: The international rules of warfare require nations to capture instead of kill enemy fighters, especially when lethal force is not the only way to take them off the battlefield.
The administration claims, in the white paper, to have conducted an exhaustive review of the laws of war, and to honor those standards. Its portrayal of the rules, however, is incomplete to the point of being wrong. The crucial assumption, which hasn't yet been challenged, is that in wartime a state can choose to kill rather than capture enemy fighters at its discretion. This is a fallacy, as a matter of current law and legal history. Correctly understanding and respecting the law in this area matters deeply for the choices U.S. Special Forces are told they can make when they hunt down a suspected terrorist. And it matters for what rules the United States sets in cooperation with its NATO allies.
If you listen to the administration's version of the rule book, you might believe that once someone is designated an enemy fighter, he can be killed anytime, anywhere. But the more you dig for a defense of this idea, the more you realize how weak it is.
Let's look at the history. In 1625, the father of international law, Hugo Grotius, wrote that "in general, killing is called a right of war" and that "according to the law of nations, anyone who is an enemy may be attacked anywhere." Grotius' approach remained operable through the American Revolution, Civil War and the world wars of the 20th century.
But the modern laws of war have come a long way. In 1967, one of the architects of the modern laws of war, the Swiss jurist Jean Pictet, stated that parties to a conflict should apply only so much force as necessary. He would later elaborate this principle: "If we can put a soldier out of action by capturing him we should not wound him, if we can obtain the same result by wounding him, we must not kill him, if there are two means to achieve the same military advantage we must choose the one which causes the lesser evil." That maxim does not require U.S. troops to endanger themselves to try to capture al Qaida terrorists. The principle simply holds that if it is unnecessary to kill an individual to take them off the battlefield, capture must be the preferred option.
Pictet's views won the day: In 1973, a group of leading intellectual figures adopted Pictet's language essentially word-for-word as a fair reflection of existing law. Around the same time, the International Committee of the Red Cross examined the state of the law in a report to world governments and stated concretely: "The principle of humanity enjoins that capture is to be preferred to wounding, and wounding to killing."
This culminated in a 1977 international conference in Geneva, which established treaties on the rules of warfare. The result was a pact agreeing to a prohibition on "superfluous injury or unnecessary suffering," words that are now included in war manuals of the U.S. military.
The foundation of the White House's position is, in the end, based on a historical relic. Nonetheless, this view has been accepted as mainstream in the United States: Even strong critics of the drone program have begun to mouth it. For example, a recent critique of the Justice Department's legal analysis accepts as a truism that "unless he surrenders, a combatant can be killed regardless of activity."
The disjuncture between the American conversation and the modern laws of wars even shows up in a recent discussion with the American political philosopher Michael Walzer. He indicated his strong support for the White House position, and stated that in "asymmetric warfare, without a front, without soldiers in uniforms, targeted killing seems a necessary form of warfare - and justified if we get the targets right. Why does risk [to U.S. forces] make a difference?" Compare this, however to the High Court of Israel's landmark judgment in 2005 on targeted killings. In a ruling that captures modern developments of international law, the Israeli judges stated that lethal forced must be abandoned when "a less harmful means can be employed." They explained that a key factor is whether such restraint involves "a risk so great to the lives of the [Israeli] soldiers."
A careful reading of law and history shows how wrong the White House position is. In law school, we teach that getting the law wrong can be as bad as ignoring it altogether. In this case, at least we still have a chance to get the law right.
Ryan Goodman is a law professor at New York University. He wrote this for Slate.


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Sean and Kelly are amazing hosts. They make you feel at home and welcome the second you step through the door. The Inn is beautiful and the rooms are very nice and big. The view from the Inn is great - beautiful nature and very...More
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|Reviews for OWL exams
| Mia chapter 1 . 6/21/2016
| Fire The Canon chapter 1 . 5/22/2013
Awwwww, this was very noble and sweet of Sirius, and I can imagine him doing something like that. Talking to the teachers on Remus' behalf, and not caring about his exams. These are the reasons I love Sirius so.
This was written really well too. A fantastic job. I loved it!
| Kailey Hamilton chapter 1 . 5/21/2013
(This may come out jumbled because I'm mobile, sorry) Oh my God. I was so sad you hadn't submitted by the time I did... I'm happy I have an opponent -a very , too- and I'll be very lucky if I win against this. I see no Wolfstar, but a really strong friendship and that makes it all the more beautiful. Your characterization of Dumbledore and McGonagall -which to me are quite difficult to write- was brilliant and flawless. Sirius and Remus were lovely as well.
Only one thing - There's a typo on Sirius' last spoken line. Other than such a minor thing, I absolutely loved this story.


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Mortimer Buckley
Mortimer Joseph Buckley, M.D.
Died November 24, 2007
Osterville, MA
United States
Boston University School of Medicine (M.D. 1958)
Professor of Surgery, Harvard Medical School
Chief, Cardiac Surgical Division, Massachusetts General Hospital
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Description: InTrickster Makes This World, Lewis Hyde brings to life the playful and disruptive side of human imagination as it is embodied in trickster mythology. He first visits the old storiesHermes in Greece, Eshu in West Africa, Krishna in India, Coyote in North America, among othersand then holds them up against the lives and work of more recent creators: Picasso, Duchamp, Ginsberg, John Cage, and Frederick Douglass. Twelve years after its first publication,Trickster Makes This Worldauthoritative in its scholarship, loose-limbed in its stylehas taken its place among the great works of modern cultural criticism. This new edition includes an introduction by Michael Chabon.
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All the information you need in one place! Each Study Brief is a summary of one specific subject; facts, figures, and explanations to help you learn faster.
List price: $18.00Copyright year: 2010Publisher: Farrar, Straus & GirouxPublication date: 8/17/2010Binding: PaperbackPages: 432Size: 6.00" wide x 8.40" long x 0.75" tall Weight: 0.968Language: English
Harold Kodais Curator in Charge andAndrew Boltonis Curator, both at The Costume Institute , The Metropolitan Museum of Art. They are coauthors ofChanel(2005),Dangerous Liaisons: Fashion and Furniture in the Eighteenth Century(2006), andPoiret(2007).Michael Chabon was born in Washington, D.C. on May 24, 1963. He received a B.A. in English literature from the University of Pittsburgh in 1985 and a Master of Fine Arts degree in English writing at the University of California at Irvine in 1987. Chabon found success at the age of 24, when William Morrow publishing house offered him $155,000, a near-record sum, for the rights to his first novel The Mysteries of Pittsburgh, which was his thesis in graduate school. After The Mysteries of Pittsburgh became a national bestseller, he began writing a series of short stories about a little boy dealing with his parents' divorce. The stories, which in part appeared in The New Yorker and G.Q., were bound together in 1991 into a volume titled A Model World and Other Stories. His other works include Wonder Boys, The Astonishing Secret of Awesome Man, and Telegraph Avenue. In 2001 he won the Pulitzer Prize for fiction for his novel The Amazing Adventures of Kavalier and Clay.
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Chris is requesting
Physics tutor
Posted Jul 04
Starting in fall 2016 and going through spring 2017 I will be taking physics at my university. It would be nice to have a tutor that I could work with.
Reviews of Chris
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About Chris Chappell
My name is Chris. I'm a full time college student at Washington State University of Vancouver studying biology with a focus in pre-vet med. I served 6 years in the United States Air Force and have bee...n a native to the great PNW all my life! I'm a huge Star Trek fan. Like, you don't even know.show moreOpen to other proposals
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It was the best night of their lives, if they could only remember.
A rag tag band of idiots on the verge of signing a recording contract is sandbagged by their lead singer, Chas Knopfler, into throwing the mother of all parties the night before they embark on a world tour. Eddie Mesmer, the rhythm guitarist, awakens to find his drummer, Toss Dunbar, hanging from a tree like a scarecrow, and the house completely destroyed. Eddie and Toss quickly realize that A: they can't remember anything and B: there's a dead guy in the pool. Now, they have to figure out what happened the night before or their Rock and Roll dream is over.
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IN 1992 the UK was in the midst of recession. After 15 years in the computer industry in a number of senior technical and marketing roles, John Goodyear started his company, System Automation, with the help of his redundancy payment, a Government Enterprise allowance and advice from Blackwater Valley Enterprise.
In 2002 John and System Automation celebrate the first ten years and the business goes from strength to strength.
System Automation provides an all-round IT service, including consultancy, PC server and systems installation, networking, electronic mail, internet access and security software to those businesses which need to have — and keep — their systems up to the demands of today's fast-moving technological developments.
Customers without an in-house IT manager can obtain the services of one from System Automation without incurring employment costs, while for those customers with an IT manager in place, System Automation can provide additional expert support and back-up.
The customer base includes a major firm of solicitors, a stockbroking and investment management business, a leading PR consultancy, and the John Lewis Group.
Many of the customers have come as a result of John's personal contacts and recommendations from satisfied customers.
He says: "So many people have a horror story to tell about IT — the systems which don't do what they are supposed to do, the salesman who sells you the kit and disappears.
"We are there to provide whatever help the customer requires. We have seen many of our customers start in quite a small way with their IT systems and then develop them with our help and expertise into something very substantial. We are there for the long-term, not for a quick profit."
At the beginning of 2001 the company moved to Bentley. A further visit from a Blackwater Valley Enterprise adviser also helped John think about his next steps.
"It's tough going sometimes as a person running a small business and the most difficult part is making time to work on your business rather than in it," he says.
For further information contact him on 01420 526300 or e-mail email@example.com.


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$4,500.00 1 year ago
2005 Acura TSX - $4500 (Columbus Ga)
1 owner excellent condition Fully loaded Xm radio station, heated seats, leather, sunroof, 190k no mechanical problems
1 year ago
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$2,800.00 1 year ago
00 Acura TL - $2800 (Columbus ga)
Fully loadedRuns and drives great A.c & heat works also has sunroof 200k miles No mechanical issues 2,800
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1999 Acura 3.0 CL - $1600 (Columbus Ga)
Car drives fine. Will need work, but is dependable in town. Some cosmetic blemishes but looks good cleaned up. Cold AC. Price is low already, but willing to negotiate. Serious inquiries only
1 year ago
Columbus, GA
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Thank you for joining Bubblest XXI! See you next year!
Bubblefest is an indoor spring break festival combining bubble artistry, real science, and spellbinding lasers for the whole family. Bubblefest XXI in 2017 featured performances by bubble artist Deni Yang in the Mega Bubblefest Laser Show. The world-famous performance artist leads a viscous variety stage show, which combines music, lasers, lighting effects, and bubble artistry to create a spectacular experience for all ages! Inside the Bubble Zone, visitors will get to create their own bubble art with wands, participate in science demonstrations, roll around in water spheres and so much more!
Mega Bubblefest Laser Show
Water Spheres
Bubble Courtyard
Cube Jr. Playground
Me In A Bubble
(additional charge)
Bubble Zone


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Too often a tike goes not there after effort lost, or a young person crashes a car after a jamboree he was not acknowledged to be at, or a trivial tiddler wanders off in a population plop. Hopefully, new and breathtaking GPS technology can belittle the likelihood that this will go on. In fact, at hand are cases wherever bad endings have been prevented by GPS chips.
In the past, GPS transmitters were huge and colossal. You could not convey them in circles bar in a rucksack or giant case. However, as GPS practical application becomes more advanced, transmitter chips and GPS trackers are acquiring slighter and more than coercive. This new people of GPS disposition can assist you line your shaver beside disposition are as dwarfish as a quality newspaper cartridge clip. Some can even be put in a serving of adornment or stitched into uniform.
A new study recovered that a considerable majority of parents would buy a instrumentation to suggestion their child's cardiovascular exercise. There are some reasons a parent would poorness to do this:Post ads:
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4. To make a contribution a hesitant child order of psyche in general population.
The way the GPS chip plant is that it gives off a impressive that can be read by a worldwide positioning satellite, which in swivel transmits the subject's entity to a inner receiving system. A genitor can later glibly log onto a website, hail as a telephone set number, or even go to a location on a web-enabled cellular phone to observe their child's situation to inside a few feet. When a parent suspects that thing is wrong, beside the move of a holdfast the child's situation can be transmitted to area personnel beside an perked up.
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World Music from the Cold Seas
Model/varenr.: SHD51
"World Music from the Cold Seas" is an independent continuation of the successful metal rock CD "Rock from the Cold Seas". Based on traditional music, the performances here are a mix of ethnic sounds of several cultures from across the land. The CD samples the multi-faceted indigenous music of the Cold Seas. Listen to the traditional beats of the Greenlandic drumdance. Or groove to a funky techno drumdance. Find out why the fresh and powerful Tyr jumped straight to No.1 in the Faroe Islands and Iceland with a rock rendition of an old Faroese ringdance. International audiences and critics alike have deemed Yggdrasil's Eivør to be one of the most talented female singers in the world. The Sami weave a spell of beautiful yoik trance. The yoik, Europe's oldest musical form, will touch you and capture you in its timelessness. Margret Ornolfsdottir's rock group the Sugarcubes introduced Bjork to the world. Klakki's "Faeding Mafsins II" is co-written by Sjon another well-known collaborator of Bjork's. The two of them were Oscar nominees for the music to Lars von Trier's film "Dancer in the dark". Let the music enchant you with the brave, new "World Music from the Cold Seas".
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Author | Noor Fathima Warsia | Thursday, Dec 08,2005 8:55 AM
The marketing and brand team at CNN-IBN is fast falling into place. The forthcoming channel from the TV18 stable has just appointed Pugmarks CEO, N Dilip Venkatraman, as Director, Marketing. Venkatraman joins the channel in the next two weeks. His appointment comes close on the heels of Zee News' Sanjay Dua joining TV18 in a senior sales function.
Needless to say that Venkatraman is excited over his new assignment. He said, "I'm delighted with this opportunity and look forward to it. CNN-IBN is one of the few brands which has managed to create significant hype even before its launch and enjoys high credibility. I look forward to the kind of work that I can do with the team there."
Venkatraman joined Pugmarks in September 2004. Prior to that, he was with Zee, where he was initially Head of Brand Management for Zee News and was responsible for repackaging and repositioning Zee.
Subsequently, he was assigned responsibility for Zee's DTH business as President, Marketing, Dish TV. He was also the man behind Zee News' wireless GSM-led tickers.


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BP's oil spill is destroying a whole food culture. While attention has been quite rightly focusing on the general destruction of marine eco-systems in the Gulf of Mexico, it's peoples livelihoods and the wider food system that is going to be one of the big losers of BP's intransigence and our societies oil dependence.
This month, the Renewing America's Food Traditions (RAFT) alliance will release a comprehensive checklist of over 240 place-based foods of the Gulf Coast that are now at risk – 138 of them directly affected by the oil spill.
As this report shows the spill is also going to hit some of the most marginalized ethnic communities in the United States, including Cajun, Houma Indian, "Creole" Black, Vietnamese, Cambodian, and Latino communities in and near the Mississippi delta many of whom have livelihoods initimalet connected weth the seafood economy.
While politicians and lawyers haggle over the price of the spill – what price the heritage and culture of people who have worked with seafood for centuries? In a Fife context its worth reflecting that Grangemouth and the other Forth pullutants have been contaminating the Firth of Forth estuary and undermining our own seafood economy for decades.


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|« Date » · « Thread »
|"Uwe Schindler (JIRA)" <j...@apache.org>
|[jira] [Commented] (LUCENE-3228) build should allow you (especially hudson) to refer to a local javadocs installation instead of downloading
|Tue, 05 Jul 2011 10:25:16 GMT
[ https://issues.apache.org/jira/browse/LUCENE-3228?page=com.atlassian.jira.plugin.system.issuetabpanels:comment-tabpanel&focusedCommentId=13059820#comment-13059820 ] Uwe Schindler commented on LUCENE-3228: --------------------------------------- Just one other idea: - We already have JAVA_HOME set (direct or implicitely set by ANT) - The Javadocs are always at same location in $JAVA_HOME Could we not use this to point to the package list (at least fpr the JDK part). I don't like the hardcoded package list. > build should allow you (especially hudson) to refer to a local javadocs installation instead of downloading > ----------------------------------------------------------------------------------------------------------- > > Key: LUCENE-3228 > URL: https://issues.apache.org/jira/browse/LUCENE-3228 > Project: Lucene - Java > Issue Type: Task > Reporter: Robert Muir > Assignee: Robert Muir > Attachments: LUCENE-3228.patch > > > Currently, we fail on all javadocs warnings. > However, you get a warning if it cannot download the package-list from sun.com > So I think we should allow you optionally set a sysprop using linkoffline. > Then we would get much less hudson "fake failures" > I feel like Mike opened an issue for this already but I cannot find it. -- This message is automatically generated by JIRA. For more information on JIRA, see: http://www.atlassian.com/software/jira --------------------------------------------------------------------- To unsubscribe, e-mail: email@example.com For additional commands, e-mail: email@example.com
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Data from: Paternal Imprinting of Mating Preferences Between Natural Populations of House Mice (Mus musculus domesticus)
Date Published: January 31, 2013
DOI: http://dx.doi.org/10.5061/dryad.53356
Content in the Dryad Digital Repository is offered "as is." By downloading files, you agree to the Dryad Terms of Service. To the extent possible under law, the authors have waived all copyright and related or neighboring rights to this data.
|56 times
|Excel file with three tables; the first table lists details for all matings evaluated, including all mating partner IDs and associated information from the monitoring surveys. The second table is a subset of the first table restricted to all matings among F1 animals that were born in the enclosure. The third table is a subset of the second table, restricted to all first matings only.
|datatables.xls (141.3 Kb)
|View File Details
|all mice in experiment
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|List of all mice that were collected and genotyped. Only animals with clear assignments were used for generating the mating data presented in the file "datatables.xls"
|all mice in experiment.xlsx (241.8 Kb)
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When using this data, please cite the original publication:
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An addin for Visual Studio 2005/2008 to auto increment build versions of projects.http://autobuildversion.codeplex.com/
|visual-studio versioning addin build build-tools build-version
The Windows Installer XML (WiX) is a toolset that builds Windows installation packages from XML source code. The toolset supports a command line environment that developers may integrate into their build processes to build MSI and MSM setup packages.build install build-tool setup installer updater
PTVS is a free & OSS add-in from Microsoft that turns VS into a Python IDE. It supports CPython, IronPython, Intellisense, debugging, profiling, Azure, etc.ide ipython ironpython magelia native
AnkhSVN is a Subversion Source Control Provider for Microsoft Visual Studio 2005, 2008 and 2010. AnkhSVN provides source code management support to all project types supported by Visual Studio and allows you to perform the most common version control operations directly from inside the Microsoft Visual Studio IDE.visual-studio-plugin plugin subversion scm-client subversion-client svn-client
CruiseControl is both a continuous integration tool and an extensible framework for creating a custom continuous build process. It includes dozens of plugins for a variety of source controls, build technologies, and notifications schemes including email and instant messaging. A web interface provides details of the current and previous builds.build-process continuous-integration build tool
The Hidden Markov Model Toolkit (HTK) is a portable toolkit for building and manipulating hidden Markov models. HTK is primarily used for speech recognition research although it has been used for numerous other applications including research into speech synthesis, character recognition and DNA sequencing. HTK is in use at hundreds of sites worldwide.speech speech-recognition speech-to-text tools
ANTLR (ANother Tool for Language Recognition) is a powerful parser generator for reading, processing, executing, or translating structured text or binary files. It's widely used to build languages, tools, and frameworks. From a grammar, ANTLR generates a parser that can build and walk parse trees. Twitter search uses ANTLR for query parsing, with over 2 billion queries a day.grammer parser language-recognition semantics
N2 is a lightweight CMS framework that helps you build great web sites that anyone can update. Web content editors can enjoy a simple and enpowering web interface. Developers will benefit from a programmer friendly API that makes building web sites quick and fun. N2 is focused on removing redundant steps when working with content types and ASPX templates. All of development is done within visual studio.cms content-management-system site-building portal
CloudStack CE is an open source Infrastructure-as-a-Service (IaaS) software platform, which enables users to build, manage and deploy compute cloud environments.cloud cloud-computing datacenter iaas infrastructure-as-a-service cloud-management
The ORMAP Parcel Editing Toolbar is a project that builds and maintains tools for editing parcel data via ESRI's ArcGIS. The tools consist of an ArcMap toolbar for use in ArcMap version 10X. CAUTION: STILL IN TEST MODE!!! 1/7/2011
Open Information Integration Tool Suite (Open II) is used by analysts and programmers to accelerate data integration and harmonization across organizations. OpenII has a neutral schema repository for browsing and comparing all sorts of data models. Release Notes Release Date: March 29, 2012 Build Version: 1.0.2639 Notes: 1. Build version numbers are now displayed in the tool suit's About OpenII page. 2. Access to new features in the Unity tool, a vocabulary editor, is now available. In add
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text:
What is your username?
Please link to the wiki here:
How many edits have you made on that wiki?
311 (as of 2 July. To put in context, Founder made 5 edits, while many other users have less than 20.)
How many days/months have you been editing there?
3 months, but have been watching the wiki closely for about 5 months.
On the Special Pages → Special:ListUsers when was the last time an admin edited, and who was it?
WolfsGhost, on 19 March 2012
Any other information:
Been meaning to apply for administrator or moderator status for a while, but the only person who is able to help me with that has been inactive for a long time. I've tried contacting him via other means (Tumblr, IRC, Legends of Equestria Forums), but I have not received any replies for over a month. I think that the wiki really needs cleanup - some pages have to be deleted (as they are only a few sentences long, and already integrated into other pages, see this page is a subset of this article), unconstructive comments removed like over here, and I've been meaning to add a wiki logo for a while now (Image has already been completed and is sitting in my computer) to make the wiki a bit more attractive. Might add a background image in the long run as well.
Timestamp: 02:56, June 24, 2014 (UTC) Talk Page on Community Central ¤ User page on LoE Wiki ¤ Talk page on LoE Wiki
- Hi. Your contributions look good, however there is another active contributor, Weatherboy1. Please talk to him about adoption and let me know on my wall when he responds or that he hasn't answered in a week. -- Wendy (talk) 04:23, July 2, 2014 (UTC)
- Well, I've actually already sent Weatherboy1 a message on his talk page about my adoption request, but he hasn't replied for a week now... Cyan Spark, 2 July 2014
- EDIT (6 July): He's replied and accepted my request!
- Well, I've actually already sent Weatherboy1 a message on his talk page about my adoption request, but he hasn't replied for a week now... Cyan Spark, 2 July 2014


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At Pharma-Sponsored Conference, Florida Medical Association Votes to Oppose Medical Marijuana
This past Sunday, the Florida Medical Association voted to oppose Amendment 2, Florida's latest effort to legalize medical marijuana. The FMA, which represents more than 20,000 physicians in the state, also opposed a similar effort two years ago.
So why is the doctors' group hell-bent against a treatment option that has been embraced elsewhere in the United States? Well, after the vote at the group's annual meeting in Orlando, CEO Tim Stapleton offered the following (factually dubious) reasoning:
"There is nothing 'medical' about this proposal, and the lack of scientific evidence that pot is helpful in treating medical conditions is far from inclusive," he said, according to a news release sent out by Drug Free Florida, the billionaire-backed campaign to scare people from voting for medical marijuana.
But the FMA neglected to mention one key fact about its vote: Its Orlando conference, held this year at Walt Disney World, was sponsored by PhRMA, one of the pharmaceutical industry's largest trade organizations. PhRMA has spent millions to defeat medical marijuana proposals across the nation.
FMA website
Pharmaceutical companies have long stood in opposition to legalized weed, because studies have shown that fewer doctors prescribe opiate painkillers in states where medical cannabis is legal. One 2015 University of Georgia study showed that a single doctor in a medical-marijuana state will prescribe 265 fewer doses of antidepressants, 486 fewer doses of seizure medicine, 541 fewer scrips for anti-nausea medication, 562 fewer anti-anxiety doses, and a whopping 1,826 fewer doses of painkillers each year.
Thus, the pharmaceutical industry has pulled out just about every stop it can to prevent the spread of legal weed. In 2013 alone, PhRMA spent $18 million on lobbying, according to campaign-donation-tracking website OpenSecrets.org.
(Some have speculated that medical marijuana's effect on the prescription-pill industry drove Publix heiress Carol Jenkins Barnett to donate $800,000 to Drug Free Florida in July. Publix is one of the largest pharmacy chains in the South.)
State funding disclosures show the group's own political action committee is largely funded through small donations from Florida doctors, but the FMA and Big Pharma seem to have a long history of lobbying collaboration.
It appears that PhRMA and the FMA have shared PR firms on at least one occasion and that the FMA has historically maintained an entire lobbying wing dedicated to "Pharmaceutical Corporate Affairs." According to one former FMA lobbyists' LinkedIn profile, that lobbying group "was a forum for collaboration between Florida's physicians and major pharmaceutical companies" such as Pfizer and Merck. The lobbyist himself had formerly worked for GlaxoSmithKline.
The Florida Medical Association's 2015 spring conference was backed by Big Pharma giants Endo Pharmaceuticals and Allergan, among other sponsors.
The group did not immediately respond to a call from New Times for comment.
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text: About 400 Orthodox rabbis and religious laymen from the U.S. and Canada will spend the Passover week in the resort town of Acapulco, it was announced by Rabbi Abraham Hershberg. President of the Latin American Board of Rabbis. They have been invited by former President Miguel Aleman, currently president of the Mexican Tourist Council, as part of the government's policy to encourage tourism. Hershberg said the Mexican government has granted the rabbis permission to bring Passover foods into the country duty-free.


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It has been a hectic few months for the Morgan Motor Company, but the company's boss, Steve Morris, says he's keen to move on from recent events and plan the company's future. Fans and the media alike were left shocked by last month's revelation that Charles Morgan, grandson of the company's founder, had been dismissed from Morgan's board of directors. That means the expansion and modernization plans favored by Charles Morgan probably aren't on the agenda. Said Morris, "We don't need massive growth and we don't want to overstretch the company."
|Morgan Motor Company Moves On, Plans Future
Source:GrabNetworks (c). All Rights Reserved


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About James Ritchey
I'm a comic book artist and writer, animator, illustrator (games and commercial), songwriter/musician and moderately nice individual from Atlanta, Georgia. I write, draw, digitally paint and letter comics, as a first love, with emphasis on the two former.
I've worked for Eclipse, New World Pictures/Goliath Studios, Radical Comix (with an 'X'), Flying Rock Productions, iHero, Vavavavoom and AC Comics, to name a few.
Professional History
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These Grade ll listed, attractive, 16th century barn conversions have been completely renovated to a very good standard. They offer glorious views over the rolling Devon countryside, and are ideally situated on a 300-acre working farm, between Cullompton and Honiton, an excellent location for exporing the many attractions nearby, including the famous World Heritage Jurassic Coast, 18 miles, Killerton House (NT), Crealy Adventure Park and the Lace Museum at Honiton, 7 miles. Also worth a visit are Beer, Seaton, Lyme Regis, Sidmouth and Branscombe. There is walking on the Blackdown Hills, or Dartmoor (within easy driving distance), and of course, Exeter cathedral city with its shops and restaurants. Set between Dartmoor and Exmoor, the cottages are well-placed to visit the quaint villages - and no visit would be complete without a Devon cream tea. Properties 27667 and 24677 can be booked together to accommodate up to 10 guests. Shops, pub and restaurant 1 mile.
Ground floor: Living/dining room/kitchen. Separate toilet. Four steps up to: 3 bedrooms: 2 double, one with en-suite shower room and toilet, 1 twin. Bathroom with shower over bath and toilet.
Freeview TV. W/machine. Enclosed courtyard. Small lawned area with sitting-out area and furniture. Parking (3 cars).
Both properties: Oil CH, elec, bed linen and towels inc. T/cot. H/chair. DVD. Elec cooker. M/wave. D/washer. F/freezer. Both properties: Oil CH, elec, bed linen, towels and Wi-Fi inc. T/cot. H/chair. DVD. Elec cooker. M/wave. D/washer. F/freezer. No smoking.


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Hello again my dear readers! It's been a while...I had an extremely busy couple of months since I accepted yet another major life decision in May. I got up my courage and decided I will try to get accepted to a fashion designer school in Ljubljana. This was a huge step out of my comfort zone, because I really really can't draw and you have to pass pretty tough entry exams (at ... Read More
Vintage Levi's and an open back bodysuit
SHOP MY LOOK: bodysuit Sheinside, vintage Levi's, sneakers Converse, backpack Foxboutique Vintage Levi's and an open back bodysuit This look is definitely not my go to outfit, I would pick for everyday. It's a little bit different than my usual ''uniform'', which consists of skinny jeans and an over-sized sweater. I use to train swimming, so I have a typical swimmer's back ... Read More
Vintage Vogue inspiration: illustrated covers
I recently took up a drawing class and my obsession with art is growing rapidly since than. Especially with the cool fashion illustrations and sketches, they make me want to learn drawing and illustrating even more. When I was searching for some fashion inspiration yesterday, I accidentally ran into some vintage Vogue fashion covers. I was absolutely fascinated with the ... Read More
Fashion trends: to follow or not to follow
SHOP MY LOOK: ZARA shirt, pants, ballerina flats (similar HERE), VIVA'S PROJECT bag Spring in pastels As you might have noticed, I'm not a big fan of color. All the way from October to March the colors I tend to pick when it comes to clothes are black, gray and dark green. I guess my looks reflect my mood, which is pretty damn depressive in the winter season. But as soon ... Read More
How to style a yellow bag
How to style a yellow bag When I bought this yellow Liu Jo bag at the end of winter I knew it would be perfect for spring and summer. But because I don't have too many colorful bags (read:zero colorful bags) I had to figure out how to style this yellow bag. It turns out, it's easier than it looks like! Are you obsessed with black? Than you are in luck. A yellow bag ... Read More
Gray is such a happy color
Blog makeover You may have noticed my website got a little makeover. The most important change is, that the blog has become bilingual, all of the articles from now on will be also available in my native language Slovenian. New categories I've also added two new categories into my blog, that will get some new articles very soon. I'm going to mix my fashion blog with ... Read More
What my favorite bloggers wore to the latest fashion week?
Jacqueline from the blog MIKUTA Aimee from the blog Song of Style Kenza blogs at Kenza Zouiten. Janni owns a blog called Janni Delér. It's time for us to get inspired from these successful and hugely popular ladies who write blogs that attract an enormous attention. And with a good reason! Their styles are unique and simply gorgeous and they also post insanely ... Read More
It's all about that bag
Yellow is such a happy, optimistic and a positive color. When I received my first regular pay check in the middle of February I decided to celebrate by buying myself a bag (surprise, surprise). I've been checking out Liu Jo bags for quite sometime and when I saw this beautiful yellow bag in the store I knew it would be perfect for up coming spring season. I'm not a big fan of ... Read More


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Product details
Durable, corrosion resistant decorative coating for ferrous and non-ferrous metals, certain plastics and wood. Decorative hammered appearance is smooth to the touch and sheds water well.
- Colour: Black
- Size: 750ml
- Coverage (per litre): 5sq m
- Coverage per tin: 3.75sq m
- Effects and finish: Hammered, Decorative
- Features: Can be applied directly onto rusty metal, Corrosion resistant
- Suitable surfaces: Metal
- Number of coats recommended: 2
- Drying time: Touch dry 1-2 hours
- Time to recoat: Recoatable after 4 hours
- Washable: Yes
- Wipeable: Yes
- Waterproof: Yes
- Interior exterior usage: Suitable for exterior use
- Also available: 250ml, 2.5L, 5L, Aerosol
- VOC level: High
Hammerite Direct To Rust Hammered Black Metal Paint - 750ml 997785
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Hammerite Direct To Rust Hammered Black Metal Paint - 750ml
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Hammerite Direct To Rust Hammered Black Metal Paint - 750ml is rated out of 5 by 1.
Rated 5 out of 5 by Anonymous from Excellent Very good quality. Only needed one coat for a really good coverage. Covered all rust with no problem, gave a nice finish.
Date published: 2016-06-22


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Accommodations in NortheimSee All
If you are looking for travel information of Northeim in Germany, you've come to the right place. This city is located in the close proximity of a major city Weimar, Germany. Add Weimar to your vacation plan, it has an interesting bunch of activities to do on your visit like Goethe National Museum And Home, Herzogin Anna Amalia Bibliothek, Bauhaus Museum. To explore Northeim, set aside 1 to 2 number of your days. You'll be coming back for more!
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Explore the best journey planner for your visit to Northeim and create a flawless plan in few simple steps!


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AHCPR-NLM Joint Initiative for Health Services Research Information: 1992 Update on OHSRI
Flagle, Charles D.
Cahn, Majorie A.
Bibliographic Citation
QRB: QUALITY REVIEW BULLETIN 1992 December; 18(12): 410-412
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Memorandum on information on a major new initiative: mapping and sequencing the human genome; to Alvin Trivelpiece, Director, Office of Energy Research DeLisi, Charles; United States. Department of Energy. Office of Health and Environmental Research. Office of Energy Research. (1986-05-06)
Department of Health: Disclosure of Information for Research Purposes. Joint Response From the Academy of Medical Sciences, Medical Research Council and Wellcome Trust on Regulations to Implement the Human Fertilisation and Embryology Act 2008 Unknown author (United Kingdom. Academy of Medical Sciences, 2008)
Medical Records Privacy: Uses and Oversity of Patient Information in Research Testimony by Bernice Steinhardt, Director of Health Services Quality and Public Health Issues, Health, Education, and Human Services Division Before the Committee On Health, Education, Labor and Pensions, U.S. Senate Steinhardt, Bernice (United States. General Accounting Office [GAO], 1999-02-24)


text: Property ID#: 32080Apartment 1 Bedroom 1 Bathroom Sleeps 32-room apartment 72 m2, on the ground floor, comfortable and tasteful furnishings: entrance hall. Living/dining room with 1 sofa bed, dining table, library, cable-TV, video and stereo unit. Exit to the garden, to the terrace. 1 double bedroom. Kitchen (4 hotplates, oven, dishwasher, micro wave) with hatch. Bath/WC. Small terrace 6 m2, patio, garden. Terrace furniture, box-room. Facilities: washing machine, dryer, telephone. Please note: apartment courtyard side. Parquet on the floors and beautiful oriental rugs.AreaSituated on the edge of the large Rapoldi park small apartment house "Wohnpark Alt Pradl". 800 m from the centre, in a quiet, sunny position, on a side street. In the house: lift, central heating. Public parking on the road. Supermarket 150 m, shopping centre 250 m, restaurant 100 m, bus stop 300 m, railway station "Innsbruck Hauptbahnhof" 1 km, outdoor swimming pool 600 m, indoor swimming pool 300 m. Tennis 150 m, sports centre 800 m, cable cabin 3 km, skisport facilities 5 km, ice rink 800 m. Short term parking zone in front of the house. Garage available on request (both extra).* Note - Local taxes and security deposit are due at arrival, payable in local currency.*** Important ***After booking, you MUST register at https://www.onlinefrontdesk.com to access your check-in instructions


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| Horatio Peel
|First Appearance
|Fable II (Mentioned)
|Last Appearance
|Fable III" (Mentioned)
Horatio Peel was a master clockmaker and the inventor of the clockwork firearm mechanism. He considered the flintlock mechanism unsatisfactory, and subsequently invented the system that allowed clockwork pistols and rifles to be made. It is also said that he created the best versions of these weapons. The pistols he built were once used in duels before the nobility realized that they were too powerful for that activity.


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2 - 0 Final
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Manchester City
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Device Maker Zimmer Recalls Knee Replacement DeviceMar 24, 2015
Indiana-based medical device maker Zimmer, Inc. has announced a voluntary recall of 11,658 Persona Trabecular Metal Tibial knee replacement devices following an increase in complaints of radiolucent lines and loosening of the device.
The recall covers the Persona Trabecular Metal Tibial Plate/Persona TM Tibia-Prosthesis, Knee, Patello/Femorotibial, Semi-Constrained, Uncemented, Porous, Coated, Polymer/Metal/Polymer, all lots land sizes, left and right. Research has shown that radiolucent lines, which show the gap between the cement and the device component, can be associated with early failure of the device. Recipients may need revision surgery to replace the defective component.
This is a Class II recall, the Food and Drug Administration (FDA) category for situations in which use of, or exposure to, a violative product may cause temporary or medically reversible adverse health consequences or where the probability of serious adverse health consequences is remote.
The recalled devices were distributed in the U.S. in Alaska, Alabama, Arizona, California, Colorado, Florida, Illinois, Indiana, Kansas, Massachusetts, Michigan, Minnesota, Missouri, North Carolina, New Jersey, New York, Ohio, Oklahoma, Pennsylvania, Tennessee, Texas, Utah, Virginia, Washington, and Wisconsin, and in Canada, Australia, New Zealand, Korea, Austria, Belgium, Germany, Italy, Luxembourg, Netherlands, South Africa, Sweden, Switzerland, and United Arab Emirates.
According to the recall announcement, all sizes and lots of the affected devices are being removed from distribution. Urgent Medical Device Recall notices were mailed to distributors, hospitals, and surgeons last month. The company asked that affected products be quarantined immediately and returned to the company. Customers may contact Zimmer at 1-877-946-2761, 8:00 a.m. and 5:00 p.m. EST, with any questions about the recall.


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A father (Lance Henriksen) invokes the demon Pumpkinhead to avenge his son's death at the hands of big-city bikers in this horror classic filled with the essence of evil.
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Buenos Dias ombre, looking for Spanish Festivals select a month or scroll. For updates on festivals in Spain join our Facebook group
Festivals in Spain in
January : February : March : April
May : June : July : August
September : October : November : December
St Anthonys Day in Spain
Celebrate the patron saint of animals by running through fire on a horse.
San Sebastians Drum Fiesta Beat the January blues away with this Spanish Fiesta.
Viana Do Bolo Spains carnival with a difference as this pre-lent fest breaks out in a flour fight.
Las Fallas
Las Fallas is Valencia's fiery Spanish fiesta delivering amazing art all on fire around the beautiful city with brass bands blaring & botas being emptied.
Jerez Festival Enjoy Andalucían Flamenco and Spanish partying.
Moors & Christians
Spains re-enactment celebration of a victory against the all conquering Moors when St George scared them off.
April Fair in Seville Enjoy the ancient traditions of Spanish Markets.
Romeria Del Rocio
As Europes largest pilgrimage ends, this great Spanish fiesta kicks off.
Baby Jumping Fiesta
No this is not a joke ! the Spanish Baby Jumping Fiesta in Calacho is the largest infant exorcism on earth, celebrated with typical Spanish style.
Caravaca A holy horse festival.
Horse Fair of Jerez Sample Spains horse fair with late nights as the town dresses in ancient traditional wear.
Batalla Del Vino
Batalla Del Vino is a crazy wine fight in a Spain's wine capital Rioja- free drink everywhere as the entire town is flooded with wine. Just after morning mass!
Lanjaron Water Fiesta
Lanjaron Water Fiesta is Spain's greatest water fight at the peak of Summer heat.
Sonar in Barcelona
Sonar Music fest tickets and line up info: we have the latest news for the next Sonar music fest here. A legendary electro techno music and arts fest.
Rototom Europe's biggest reggae music festival.
Santísima Sangre
Valencias celebration of Christ where locals are chased in off a pier by a bull.
Fiesta of the Near Death Experience
Rejoice and remember those of the nearly departed.
Nava Cider Fiesta
Enjoy a few days of the traditional Spanish Sidra pouring fiesta.
Bull Running in Pamplona & The Fiesta of San Fermin
Bull running in Pamplona. Can you run with the bulls and party all night ? The Fiesta of San Fermin has something for everyone.
Flamenco Fiesta in Gaucin
Andalucia is the home of Flamenco and nowhere is it better sampled then at the Flamenco fiesta of Gaucin.
Running of the Nudes
PETA and Pamplona's naked "anti-bull run" bull run protest to Fiesta San Fermin .
La Raima in ValenciaIf it's a bad grape harvest don't worry-Valencias Grape throwing fiesta will lighten the mood.
Sanlucar Fiesta The town celebrates on the beach with exciting horseraces.
Semana Grande Bilbao The town of Bilbao holds a week long party.
La Tomatina Fiesta
La Tomatina Fiesta : tomato throwing where a quaint Spanish village turns into a pool of tomatoes.
Grape throwing Fiesta in Mallorca
Mallorca have an official end to their grape season with a parade, lots of music and a grape throwing fiesta.
Festes De La Merce
Barcelonas celebration of the Virgin of Mercy with free concerts, street parties and late nights.
Ibiza Closes Down In Ibiza the last party is always the biggest.
Contribute a Spanish Festival to our list
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Rototom Sunsplash 2010 in Benicassim, Spain
Not rated yet
So much more than just a music festival, Rototom Sunsplash is a real holiday: during the daytime, those not attending the various debates and workshops
Things change, always check details with a second source. We do not guarantee the validity of information found here and on associated websites and therefore can not be held liable. www.FestivalPig.com © All Rights Reserved 2007-2015.


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Russell Boivin
// November 9th, 2009 // Recommendations
"Michael has earned the respect from his team, co-workers and Senior Management. Michael is creative, knowledgeable and well diverse in various technologies. He has a better understanding of the concepts of software design and engineering than most people I have encountered over my 25 years in the industry. Michael's ability to understand and interrupt the needs of the business and convey that information to his team has improved the level of service to the customers. He is one of the more thorough individuals in architecting is code design beforehand and has produced a higher quality product. Michael's investment into the team by mentoring and training has increased the throughput of the development team but also improved the level of quality in the product."


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No announcement yet.
Poor brainless sheep like society...
new posts
I definitely agree with a few people around here that have a problem with the apparent condescension of calling others sheep or sheeple.
Don't get me wrong, I understand the frustration that is felt due to the "unenlightened" masses that surround us every day, but really, aren't we all unenlightened? You and I may know more about diet and nutrition than most of people do, but I bet you take the mechanics word on the condition of your car after an accident, or an astronomer's word on how far the moon is away from the earth, or your grand mother's word on how to cook a perfect turkey. Just because you're listening to someone about a topic they supposedly know more about than you, does not make you some sort of human/ungulate hybrid. The same can be said for most people's understanding of health and nutrition. Thy learn about it from doctor's and the media, we can only work at changing the current paradigm, and hope that the work pays off.
Originally posted by carlh View PostAngry post warning.
I f*cking hate this condescension of calling people who don't agree with you "brainless sheep". It's so friggin' holier-than-thou. Instead of insulting people who haven't learned what you've learned why not show a little patience and compassion? Human society has it in its best interest for individuals to trust each other, yes, something akin to herd mentality. It's gotten us this far. For a lot of things that works. When things are wrong with that it takes time to change the way of thinking. It's got mass and it's got momentum. Anyway, the primal/paleo-whatever mindset is gaining in huge leaps and bounds recently. You know what probably 98% of people here did before they learned about primal/paleo? The standard 'merrikan diet. Then they learned this mindset and diet plan. It feels extremely hypocritical to rant about people (ugh, "sheeple") who are doing exactly what you were doing a year or two or five ago because they haven't kept up with you.
We all pick and choose and have our biases to some extent, it always pays to be humble. No one is totally infallible.Last edited by J_walking_jonny; 02-01-2012, 03:23 AM.
I keep telling her she needs to eat more fat, but it's like she pretends I didn't say it and proceeds to ask a different question instead of facing that one.
I'd ignore you too if you told me to eat more fat.
Check out my blog. Hope to share lots of great recipes and ideas!
Originally posted by sbhikes View PostI think we're actually closer to lemmings than sheep. I mean, a long time ago I learned that birth defects can happen to the third generation. In other words, you can be affected by something your grandmother did. Well, when I was a child, diabetes was really uncommon and mostly something you got in childhood. Eventually I heard a lot about what was called "Adult Onset Diabetes". Seemed really common in the boomer generation. Now it's called Type II diabetes because children are getting it. There are lots of studies where the first generation is exposed to a bad substance, the 2nd generation is somewhat affected with birth defects or other problems, then the third or fourth is unable to reproduce. So now we have what used to be an adult disease happening in children. We have Low T commercials on TV. We have PCOS. Infertility treatments are common. So many problems with our hormones. How much you wanna bet the young people being born now find it very difficult to get pregnant 25 years from now? How much you wanna bet their children will find it almost impossible? A freakin' farmer could see something was up if he saw this sort of progression happening in his cattle or pigs but we can't see it in the human population? I'm not going to call people who can't see this trend sheeple or whatever. I wouldn't even expect anyone to link it to something as mundane as sugar and industrial seed oils. The first thought would be cancer-causing chemicals or GMO or something scary-sounding, not stuff associated with happiness and health. But you'd think university professors or doctors or SOMEBODY with brains would notice what is happening to us and figure it out.
Originally posted by jimhensen View PostChildren getting type 2 diabetes has everything to do with their diet NOW and not what their parents or grandparents ate. Please find me an active kid that isn't obese with type 2 diabetes. I don't think even one exists. As for fertility drugs being more prevalent now; I think that has more to do with people lacking patience than an actual issue. They talk about infertility in the Bible...this isn't some new phenomenon.
Time to take epigenetic inheritance seriously
There is strong evidence that rationing during WW2 in the UK followed by post-war rationing has produced an inherited thrifty phenotype for subsequent generations. Thus inherited epigenetics can be a contributing factor to obesity and diabetes for some individuals at least.Last edited by paleo-bunny; 02-01-2012, 07:36 AM.F 5 ft 3. HW: 196 lbs. Primal SW (May 2011): 182 lbs (42% BF)... W June '12: 160 lbs (29% BF) (UK size 12, US size 8). GW: ~24% BF - have ditched the scales til I fit into a pair of UK size 10 bootcut jeans. Currently aligning towards 'The Perfect Health Diet' having swapped some fat for potatoes.
You know, what is disturbing is a rise of insulin resistance, cushings and hormonal disorders in horses. They used to be very uncommon and relegated to old horses. Now you see younger and younger horses inflicted. Mine was just diagnosed with hormone shortage (it manifested itself in anxiety with her, but other mainfestations include a lack of circulation to the feet causing issues, inability to lose weight, decrease in muscle, inability to put on muscle, anxiety, fatigue). Looking back, sweet feeds - with high sugar percentages- always set her off, so I focus on giving her higher protein/fat feeds.
What's changed? Horses now get less activity- many are stalled and few have the hard work of a farm horse. And they are fed feeds that are concentrated in starches and soy products and they have in large part replaced a diet that used to be grass and hays, with some whole grains like oats, corn or bran fed to support work.
Totally different system than humans, but a similar change to a diet more concentrated in sugar, starch and soy, coupled with an decrease in activity leads to a similar disease type.
Check out my blog. Hope to share lots of great recipes and ideas!
Yes the diet has changed a lot as the diabetes has gotten younger, but don't forget what the 50s was like when people drank kool-aid and used margarine and it's not like we didn't have those things plus tons of packaged crap and fast-food in the 70s either. I ate a lot of pop-tarts and cereal with skim milk and sugar growing up. Don't forget about Tang. This dietary change has been going on for a while, and yes it has been increasing, but it has been a long time that people have not been eating real food because fake food (not to mention stuff like DDT) was associated with "Progress". When it first came out, it didn't seem to hurt people of my parent's generation. It hasn't harmed me as much as some of the younger folks on this forum. I've been eating the same dwarf hybrid wheat as everyone else my whole life. The harm seems to be accumulating. Even all those kids nearby me in wealthy Montecito with their pasty skin and pudgy bodies and vegan chefs don't look normal.Female, 5'3", 50, Max squat: 202.5lbs. Max deadlift: 225 x 3.
Putting a horse in a stall and feeding it granola is not ideal - but it's now the norm - so people automatically assume that it's fine - because everyone else is doing it. Again, that falls under sheep mentality.
It's always sheep mentality when you don't seek your own information and knowledge. When you just accept what's in front of you and have no drive to search deeper/broader.
Knowledge seekers are rare.


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Shure PG58-QTR Dynamic Microphone with XLR to 1/4" Phone Mic CableProduct #270287 Shure 270287 YNAB Dynamic Microphones https://www.esnapw.com/rses/ESnapServlet?MerchantNumberSent=63655
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Superb vocal clarity!
The Shure PG58-QTR Dynamic Mic is a solidly built dynamic microphone with a 1/4" phone mic cable excellent for backup and lead vocals. Internal shockmounting minimizes handling noise. The mic's smooth frequency response with improved mid and high end coupled with a more uniform cardioid pattern offers better gain-before-feedback. The Shure PG58-QTR features a neodymium magnet, pop filter, and on/off switch. Cardioid pattern rejects noise and minimizes feedback. Frequency response: 60Hz-15kHz. Includes 15' - 1/4" phone cable, clip, and storage bag.
- Rock-solid performance for backup and lead vocals
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- Frequency response: 60Hz-15kHz
PG58-QTR Dynamic Microphone with XLR to 1/4" Phone Mic Cable Specifications:
- Frequency response: 60-15,000Hz
Impedance: 300 ohm
Output at 1,000Hz: -53dBV/Pa (2.2 mV)
11.3 oz


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Company/Organization : Rural Health Community Center
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