text:
Mutations in the satellite cell gene MEGF10 cause a recessive congenital myopathy with minicores
- First Online:
- Received:
- Accepted:
- Citations
- 1.1k Downloads
We ascertained a nuclear family in which three of four siblings were affected with an unclassified autosomal recessive myopathy characterized by severe weakness, respiratory impairment, scoliosis, joint contractures, and an unusual combination of dystrophic and myopathic features on muscle biopsy. Whole genome sequence from one affected subject was filtered using linkage data and variant databases. A single gene, MEGF10, contained nonsynonymous mutations that co-segregated with the phenotype. Affected subjects were compound heterozygous for missense mutations c.976T > C (p.C326R) and c.2320T > C (p.C774R). Screening the MEGF10 open reading frame in 190 patients with genetically unexplained myopathies revealed a heterozygous mutation, c.211C > T (p.R71W), in one additional subject with a similar clinical and histological presentation as the discovery family. All three mutations were absent from at least 645 genotyped unaffected control subjects. MEGF10 contains 17 atypical epidermal growth factor-like domains, each of which contains eight cysteine residues that likely form disulfide bonds. Both the p.C326R and p.C774R mutations alter one of these residues, which are completely conserved in vertebrates. Previous work showed that murine Megf10 is required for preserving the undifferentiated, proliferative potential of satellite cells, myogenic precursors that regenerate skeletal muscle in response to injury or disease. Here, knockdown of megf10 in zebrafish by four different morpholinos resulted in abnormal phenotypes including unhatched eggs, curved tails, impaired motility, and disorganized muscle tissue, corroborating the pathogenicity of the human mutations. Our data establish the importance of MEGF10 in human skeletal muscle and suggest satellite cell dysfunction as a novel myopathic mechanism.
KeywordsMEGF10 Whole genome sequencing Linkage analysis Congenital myopathy Satellite cells Cleft palate
Congenital myopathies result from a variety of genetic defects [1] that manifest histologically as a disturbance in the structure or organization of myofibers, evident on biopsy by abnormalities such as minicores, central cores, central nuclei, ragged red fibers, nemaline rods, or rimmed vacuoles [2]. By contrast, muscular dystrophies are a class of myopathy in which normally developed muscle tissue undergoes destructive cycles of degeneration and regeneration, leading to distinct pathological hallmarks, including replacement of muscle tissue with fat and infiltration of endomysial connective tissue [3]. These features are usually absent from congenital myopathies, and likewise, minicores and other myopathic disruptions are typically absent from dystrophic muscle. Multiminicore disease (MmD) is an autosomal recessive congenital myopathy characterized by predominantly axial and proximal muscle weakness, frequently in conjunction with progressive scoliosis and respiratory difficulties. The defining histological feature is the presence in a large proportion of muscle fibers of minicores, short regions of sarcomeric disorganization with few or no mitochondria [4]. Mutations in the genes SEPN1 and RYR1 explain many but not all cases of MmD [5, 6, 7, 8].
The discovery of the genetic basis for such Mendelian diseases has been facilitated by efficient genomewide sequencing methods, notably exome sequencing [9] and whole genome sequencing [10]. Although selective sequencing of exons is currently cost-effective, sequencing of the entire genome offers the opportunity to identify non-exonic variants, extract higher resolution information on copy number and structural mutations, and potentially provide superior coverage of the exome than targeted capture methods achieve. Regardless of the choice of technology, either multiple probands with a genetically homogeneous disease [11] or linkage data [12] are generally required to filter variant lists sufficiently to implicate specific pathogenic mutations. Small families previously considered inaccessible to conventional genetic approaches can now be studied through a combination of linkage analysis and genomewide sequencing.
Materials and methods
Written informed consent was obtained for all subjects for participation in this study, which was approved by the Institutional Review Board of Children's Hospital Boston (CHB). Zebrafish experiments were conducted in compliance with the guidelines of the CHB Institutional Animal Care and Use Committee. Saliva or blood samples were collected and genomic DNA was isolated. Muscle biopsy slides were reviewed, and for subject 105-1, total RNA was extracted from muscle tissue. All six members of family 1030 were genotyped at 10,204 single nucleotide polymorphisms (SNPs) using the GeneChip Human Mapping 10K 2.0 Xba Array (Affymetrix). Genomewide multipoint parametric linkage scans were performed using MERLIN v1.1.2 [13] with a recessive model, as described previously [14]. Whole genome sequencing and preliminary analysis (initial mappings of reads, local de novo assembly, and variant calling) were performed by Complete Genomics, Inc. using a sequencing-by-ligation method with unchained reads [15]. Polymerase chain reaction (PCR) and Sanger sequencing were performed according to standard protocols. Mutations were genotyped in control subjects using Custom TaqMan SNP Genotyping Assays (Applied Biosystems).
Four custom morpholinos (Gene Tools, LLC) were designed against the intron 4–exon 5 (MO1), intron 5–exon 6 (MO2), exon 8–intron 8 (MO3), and exon 17–intron 17 (MO4) junctions. These morpholinos were intended to induce skipping of the targeted exons, homologous to human exons 7, 8, 10, and 19. MO1 and MO2 were designed against the 3′ splice acceptor side of the intron, and a full exonic skip would induce a frameshift and premature truncation of megf10, whereas MO3 and MO4 were designed against the 5′ splice donor side of the intron, and a full exonic skip would induce an in-frame deletion of the exons homologous to those mutated in family 1030. Zebrafish injections, birefringence assays, histochemistry, and immunohistochemistry were performed as described previously [16,17]. For electron microscopy (EM), ultrathin sections were stained with uranyl acetate and lead citrate and were observed with an FEI Tecnai Spirit at 80 kV.
Case reports
Subject 105-1 was a female Caucasian with distant Portuguese ancestry, diagnosed with MmD. No one else in her family was affected. At several weeks of age, she presented with hypotonia, initially manifesting as a weak neck and floppy head. A markedly high arched palate and failure to thrive as a result of poor feeding were noted, as were blue-tinged sclera and hyperflexible joints. She had frequent acute episodes of pulmonary infection as a child but reported no chronic breathing problems and breathed unassisted at night. Serum CK level at age 10 years was mildly elevated at 302 U/L (upper limit of reference range 105 U/L), and mild scoliosis was reported at the same time, which progressed to 20° by age 12 years. Throughout childhood, she continued to exhibit a mild, non-progressive, primarily proximal weakness (including facial weakness), as well as deficits in motor performance. Muscle biopsy showed marked fiber size variation, internalized nuclei, and slightly increased endomysial connective tissue, as well as prominent patches of decreased NADH activity within myofibers, consistent with moth-eaten fibers or minicores (Online Resource 2). Electron microscopy showed focal areas of Z-band disarray devoid of mitochondria and extending across a few sarcomeres in the longitudinal axis, confirming the presence of minicores.
Linkage analysis
Family 1030 produced positive LOD scores at sixteen genomic loci, ten of which approached the theoretical maximum LOD score of 1.329, and which collectively contained over 1,000 candidate genes (Online Resource 3). Both SEPN1 and RYR1 were excluded, as were ACTA1 and TPM3, in which mutations cause congenital fiber type disproportion [18,19], a myopathy clinically similar to MmD. The linkage intervals included the myopathy genes MYOT and CRYAB [1], but neither of these contained coding or splice site mutations by Sanger sequencing.
Whole genome sequencing and mutation analysis
Whole genome sequencing of one affected subject from family 1030 yielded a mean coverage depth of 74-fold, with 95.9% of the genome fully called (Online Resource 4). We screened all 16 linked regions for genes containing either homozygous or compound heterozygous variants that altered the amino acid sequence or consensus splice site sequence of an encoded protein. Four linked genes contained putative compound heterozygous, nonsynonymous mutations absent from dbSNP v131. Sanger sequence analysis of three called variants in ZNF99 showed that all three were homozygous for the reference sequence in all family members; ZNF99 is a highly repetitive gene and the variant calls may have been due to misaligned reads. Mutations in LOC100128682 and LAMA5 were likewise excluded, as they failed to segregate with the phenotype in the entire family. By contrast, the heterozygous missense mutations c.976T > C (p.C326R) and c.2320T > C (p.C774R) in MEGF10, the sole remaining candidate, were confirmed by Sanger sequencing to be in trans in affected subjects and to segregate with the myopathy in all six family members.
Missense mutations in MEGF10 in congenital myopathy patients
Amino acid substitution
Total controls genotyped
Controls with European ancestry
c.211C > T
39/41 species
c.976T > C
EGF-like 6
43/43 species
c.2320T > C
EGF-like 16
43/43 species
By Sanger sequencing, we screened the entire open reading frame of MEGF10 in 190 additional patients with unexplained myopathies, as well as selected exons in another 82 patients. One subject was identified with only a single demonstrable heterozygous mutation; subject 105-1 carried a novel c.211C > T (p.R71W) mutation that was absent from dbSNP v135, 1,000 Genomes data, ESP data, 56 internal genomes, and 699 genotyped unaffected control subjects. The p.R71 residue is conserved in 39 of 41 species (two species of fish having different hydrophilic residues, in contrast to the hydrophobic mutant residue tryptophan). The c.211C > T mutation was heterozygous in an unaffected parent of subject 105-1, so it was not de novo dominant. Sanger sequencing further revealed that the subject had no coding or splice site mutations in SEPN1 or RYR1. To search for a second recessive mutation in MEGF10, we sequenced its entire open-reading frame in reverse-transcriptase PCR (RT-PCR) amplicons derived from skeletal muscle RNA. Expression of both alleles at the c.211C > T site in exon 4 was verified by amplification and sequencing of full-length cDNA. However, we did not identify a heterozygous exonic copy number change, inversion, or other structural mutation. Nevertheless, because the p.R71W mutation is a nonconservative substitution not found in control subjects, there were no nonsynonymous mutations in SEPN1 or RYR1 in this patient, and the clinical and histological characteristics were similar to those of family 1030 patients, subject 105-1 may carry a second mutation in MEGF10 that we were unable to detect.
Knockdown of megf10 in zebrafish
To provide additional evidence for the pathogenicity of MEGF10 mutations, we knocked down expression of full-length zebrafish megf10 using four antisense splice-blocking morpholino oligonucleotides (MOs), referred to as MOs 1, 2, 3, and 4 (Online Resource 5). We compared the morphant phenotypes induced by injection of these MOs to uninjected, wild-type fish and fish injected with a standard control morpholino (COMO). The ability of the four MOs to block splicing was verified by performing RT-PCR on total RNA harvested from treated zebrafish (Online Resource 6). All MOs induced the formation of mis-spliced products to some extent, but they generally produced multiple bands not necessarily corresponding in size to the amplicon predicted to result from full skipping of the targeted exon.
In morphant fish with severely curled tails, particularly those treated with MO2, the organization of muscle tissue was irregular, with the tail somites showing a less distinct V-shaped chevron pattern than control fish (Fig. 3b). This apparent muscle defect was further investigated using birefringence, the ability of highly organized sarcomeres to rotate polarized light, which can be used to assess muscle integrity [22]. Fish treated with 6 ng of MO1 showed a reduction in birefringence, and 6 ng of MO2 induced a more dramatic decrease in birefringence that corresponded in its location to the disruption of somite structure evident by brightfield microscopy. The abnormal tail morphology and reduced birefringence in megf10 morphants closely resembled the phenotypes of morphant fish with deficits in known muscular dystrophy gene orthologs [16,23, 24, 25].
MEGF10 encodes multiple epidermal growth factor (EGF)-like domains 10 (MEGF10), which contains 17 atypical EGF-like domains, each with eight cysteine residues [26]. The p.C326R and p.C774R mutations substitute the fourth and sixth cysteines of EGF-like domains six and sixteen, respectively, for arginines. All eight cysteines in other proteins containing eight-cysteine atypical EGF-like domains form disulfide bridges [27], indicating the mutations in family 1030 likely disrupt MEGF10 protein structure. Similarly, the p.R71W mutation in subject 105-1 is a nonconservative substitution within the emilin domain, which may function in protein–protein interactions [28]. All three mutations were predicted by PolyPhen [29] to be "probably damaging", and the two cysteine substitutions were predicted to disrupt annotated disulfide bond sites, as expected.
Nonsense and frameshift mutations in MEGF10 were recently determined to be the cause of a severe congenital myopathy with diaphragmatic weakness, areflexia, and dysphagia. One reported family was compound heterozygous for the c.2320T > C (p.C774R) missense mutation we identified in family 1030 and a frameshift mutation [30]. The phenotypes described therein are generally similar to those of families 1030 and 105, but are more severe. This difference is consistent with the total loss of detectable MEGF10 expression observed in the reported families, compared to the expected misfolding of MEGF10 protein due to disruption of disulfide bonds in family 1030. Accordingly, affected members of family 1030 may retain a small amount of residual MEGF10 function, though genetic background or other factors could also account for clinical heterogeneity between families. Moreover, minicores were not noted in the biopsies from the reported families with null mutations [30,31] but were a prominent feature in our patients with missense mutations. Unstructured minicores in MmD may result from primary defects affecting intracellular redox state or regulation of excitation–contraction coupling at the triad [32]. The molecular mechanisms by which SEPN1 and RYR1 mutations result in minicores in MmD have not been elucidated, and likewise, the relationship between MEGF10 mutations and minicore formation is unclear. Further characterization is required to determine the effect of missense mutations on MEGF10 protein function and sarcomeric structure and to investigate whether MEGF10 shares a functional pathway with SEPN1 or RYR1.
Human MEGF10 or mouse Megf10 protein has been described as an engulfment receptor expressed in the brain [33, 34, 35] and involved in phagocytosis of apoptotic neuronal corpses [36]. One of the patients in family 1030 had overt cleft palate at birth, while a second patient had a midline ridge on her palate and a tendency to reflux liquids into her nose. All three affected subjects had hypernasal speech, which can be a sign of submucous cleft palate [37]. Subject 105-1 had a high-arched palate and poor feeding as an infant. Of seven patients in four reported families with congenital myopathy and mutations in MEGF10, one patient had cleft palate and an additional three patients had high-arched palate [30]. Although these clinical features are relatively nonspecific, occurring commonly in patients with myopathic facies, the expression of mouse Megf10 in brain [35,38] is consistent with a role in craniofacial development. In addition, Megf10 interacts with Ap2m1, one of four subunits of the assembly protein complex 2 (AP2) [35]. Ablation of Ap2b1, which encodes another of the AP2 subunits, causes cleft palate in mouse [39]. Furthermore, Megf10 in muscle is only expressed in cells that also express Pax7 [38], and Pax7−/− null mice exhibit facial malformations of the maxilla and nose due to a defect in cephalic neural crest development [40]. Lastly, some morphant zebrafish treated with MO1 or MO2 showed small heads relative to control fish, further suggesting a possible role for megf10 in head development. Collectively, these data indicate that MEGF10 may influence palate formation or facial midline determination in humans, but more research is required to test this hypothesis.
In addition to brain, mouse Megf10 is expressed in muscle satellite cells [38,41], a population of committed, myogenic precursors that specifically express the transcription factor Pax7 and contribute to the regeneration of adult muscle in response to exercise, disease, or injury [42,43]. The importance of satellite cell function in mouse muscle maintenance has been demonstrated; Pax7−/− mice have a reduced number of satellite cells as embryos and very few or none as adults, and muscle regeneration is impaired in these mice [44]. Recent studies further confirmed that Pax7+ satellite cells are completely required for muscle regeneration [45, 46, 47], suggesting that in humans, compromised satellite cell function could result in a myopathic phenotype. Expression of Megf10 in skeletal muscle is restricted to satellite cells and is low in resting muscle but increases dramatically in regenerating muscle upon activation of satellite cells by treatment with cardiotoxin [38]. Megf10 regulates the differentiation program in skeletal myoblasts, as overexpression of Megf10 in C2C12 myoblasts increases proliferation and decreases differentiation, whereas knockdown of Megf10 in primary myoblasts and individual myofibers causes precocious differentiation and a reduction of activated satellite cells [38].
Consistent with the role of Megf10 in mouse myoblasts, our data establish that human MEGF10 is required for normal muscle function. Due to presumed disruption of disulfide bonds, the p.C326R and p.C774R mutations in family 1030 likely result in a loss of MEGF10 function, in which case we hypothesize that excessive differentiation of satellite cells could deplete the population of self-renewing cells available to regenerate damaged muscle fibers. Such impairment could potentially explain the dystrophic features observed in patient biopsy tissue at ages 8 and 9. Notably, a recent study found that Sepn1−/− null mice showed a decrease in the baseline number of satellite cells in adult skeletal muscle, as well as imperfect muscle regeneration in response to a first injury and an inability to regenerate muscle following a second injury. MmD patients with SEPN1 deficiency also had a reduction in their satellite cell population [48]. These data suggest that both MmD and the myopathy described here, which share some clinical and histological characteristics, may arise through a common pathogenic mechanism of satellite cell dysfunction.
The authors thank the patients and their families for their participation in this study, as well as Hal Schneider, Laura Moody, Susan Kim, Sachiko Kajino, Kanako Goto, and Yukiko Hayashi for technical assistance, Michael Lawlor and Pankaj Agrawal for helpful discussions, Fedik Rahimov for critical reading of the manuscript, and Timothy Yu and Christopher Walsh for contribution of control genome sequence data. This work was supported by NIH K08 NS048180 (PBK), the Genise Goldenson Fund (PBK), a Children's Hospital Boston Pilot Grant (PBK), Muscular Dystrophy Association Research Grants 186796 (PBK) and 201302 (AHB), the Bernard F. and Alva B. Gimbel Foundation (LMK), NIH R01 AR044345 (AHB), the Lee and Penny Anderson Family Foundation (AHB), and the Professor-Dr.-Adolf-Schmidtmann-Stiftung (FD). Microarray genotyping and Sanger DNA sequencing experiments were performed in the Molecular Genetics Core Facility at Children's Hospital Boston, supported by NIH P30 HD18655 through the Intellectual and Developmental Disabilities Research Center and NIH P50 NS40828 through the Neuromuscular Disease Project. Electron microscopy was performed at the Harvard Medical School EM Core Facility with the assistance of Maria Ericsson, Louise Trakimas, and Elizabeth Benecchi.
Conflict of interest
The authors declare that they have no conflict of interest.
Open Access
This article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited.
Supplementary material
Normal movement of uninjected wild-type zebrafish at 4 days post-fertilization Uninjected wild-type zebrafish had straight tails and rapidly swam away in a straight trajectory when touched. (MP4 116 kb)
Normal movement of COMO-treated morphant zebrafish at 4 days post-fertilization COMO-treated zebrafish had straight tails and rapidly swam away in a straight trajectory when touched. (MP4 129 kb)
Impaired movement ofmegf10morphant zebrafish at 4 days post-fertilization A morphant zebrafish treated with 3 ng of MO1 had a slightly bent tail tip and did not initially respond to touch, but was later able to swim away. (MP4 249 kb)
Impaired movement ofmegf10morphant zebrafish at 4 days post-fertilization A morphant zebrafish treated with 6 ng of MO1 had a gently curved tail and spastic tail movements that turned the fish in circles but were ineffective for locomotion. (MP4 202 kb)
Impaired movement ofmegf10morphant zebrafish at 4 days post-fertilization A morphant zebrafish treated with 3 ng of MO2 had a severely curved tail and displayed an unproductive quivering motion, capable only of rotating the fish, either autonomously or in response to touch. (MP4 235 kb)
Impaired movement ofmegf10morphant zebrafish at 4 days post-fertilization A morphant zebrafish treated with 6 ng of MO2 had a severely curved tail and displayed an unproductive quivering motion, capable only of rotating the fish. (MP4 218 kb)
Impaired movement ofmegf10morphant zebrafish at 4 days post-fertilization A collection of fish treated with 12 ng of MO3 showed unhatched eggs, varying degrees of tail curvature, and a range of response to touch, from normal linear swimming to unproductive, rapid undulation of the tail resulting only in spinning in place. Heartbeats were observed in all fish to verify they were alive. (MP4 122 kb)
Impaired movement ofmegf10morphant zebrafish at 4 days post-fertilization A collection of fish treated with 12 ng of MO4 show moderately curved tails and very limited response to touch. Heartbeats were observed in all fish to verify they were alive. (MP4 283 kb)


text:
Dr. Chih Cheng MD Patient Reviews
- Dermatology Chapel Hill, NC
Overall Rating
15 Patient Reviews
- Friendly Staff
- Promptness
- Wait Time 8.3 minutes
- Appropriate Followup
- Spends Time With Patients
- Bedside Manner
- Fair and Accurate Diagnosis
- Easy Appointments
Showing 1 - 12 reviews
5.0 of 5
August 28th, 2016
An excellent doctor.
Dr. Cheng is very thorough in her examination and very easy to talk to.
5.0 of 5
May 24th, 2016
I saw Dr. Cheng at her previous place of employment. I rally want to see her again. I am happy that she is having twins, but sorry that I won't be able to see her until the fall.
5.0 of 5
December 27th, 2014
A wonderful dermatologist
I think she's professional, thorough, and smart.
5.0 of 5
November 13th, 2014
Excellent Dermatologist!!!!!!!!
Dr. Cheng is the most thorough dermatologist I have ever visited. She takes the time to talk to you and performs the most complete exam I've ever had. She is personable, friendly, easy going and explains things very well. I am sad to learn that she is leaving The Dermatology Center of Raleigh, and found this site while looking to see where she is moving to. 4 Stars across the board! Hopefully we will find out where she is practicing next.
5.0 of 5
May 23rd, 2012
Very thorough doc!
Dr. Cheng is very no-nonsense. She moves quickly, speaks quickly, types about a thousand words a minute, and is an excellent diagnostician. For an all-business, no frills, practical, effective doctor, she's the one! She's also quite nice -- if you can keep up with her!!
5.0 of 5
July 7th, 2017
4.0 of 5
January 31st, 2017
5.0 of 5
December 22nd, 2016
5.0 of 5
July 28th, 2016
5.0 of 5
January 22nd, 2015
5.0 of 5
November 13th, 2014
5.0 of 5
October 9th, 2014
Health Guides
Get the important facts about acne, including the different types and what causes it.
more health guides
Nearby Doctors
Dr. Chih Cheng, MD is similar to these 3 Doctors near Chapel Hill, NC.
Chapel Hill, NC
Chapel Hill, NC
Chapel Hill, NC

subset: commoncrawl


text:
"It's encouraging to see the US taking an enlightened approach to exchanges," Wray said.
"This, together with comments from seasoned observers in Australia and elsewhere suggest that the international racing world is recognising the benefits exchanges can bring.
"British racing is flourishing. Every metric relating to it has shown impressive growth in the last few years, in a period when betting exchanges have become firmly established in the market.
"Despite claims to the contrary, the sport is better funded than ever, and interest in British racing, both from within Britain and from overseas, is at an all-time high. The same can happen overseas, and betting exchanges have a significant role to play in that process. Betfair has made it very clear that it wishes to pay appropriate product fees as it expands overseas."


text:
Technology, Bureaucracy, and Healing in America: A Postmodern Paradigm
Bulger, Roger J.
Bibliographic Citation
Iowa City: University of Iowa Press, 1988. 97 p.
Permanent LinkFind in a Library
MetadataShow full item record
Related items
Showing items related by title, author, creator and subject.
Healing America: Hope, Mercy, Justice and Autonomy in the American Health Care System Bulger, Roger J. (2010)
Integrity in Health Care Institutions: Humane Environments for Teaching, Inquiry, and Healing Bulger, Ruth E. and Reiser, Stanley J. (1990)
Patient-Physician Covenant Crawshaw, Ralph; Rogers, David E.; Pellegrino, Edmund D.; Bulger, Roger J.; Lundberg, George D.; Bristow, Lonnie R.; Cassel, Christine K.; Barondess, Jeremiah A. (1995-05-17)...We believe the medical profession must reaffirm the primacy of its obligation to the patient through national, state, and local professional societies; our academic, research, and hospital organizations; and especially through ...


text:
My brother Frank had been having a few headaches and some slight memory issues so he went to the doctor and had a MRI. They discovered a mass the size of a plum in his left temporal lobe. They removed the tumor successfully, but after the biopsy, found out that he had a Glioblastoma Multiforme IV brain tumor and was given approx 3-6 months to live.
Frank had radiation for a couple of months and had chemo for about a year. He had a clean MRI in February of 2008, and we were all so hopeful that he was making a recovery and would go into a long remission.
On April 13th, 2008, Frank had a seizure and fell into a coma. They found out that he had a brain hemorrhage, probably caused by the blood thinners he was taking. Frank passed away very early in the morning on April 15, 2008, and I miss him so much every single day of my life. He was only 45 when he died and he left behind a teenage son that he was the sole parent of.
I miss you and I love you Frank!
Comments for I Miss You Frank
Click here to add your own comments
Tap into the compassion, support and wisdom of the
Free Stress


text:
The power to draw power from spiritual flame. Variation of Affinity.
Users are able to acquire power from spiritual flame which augments the user's spiritual and physical attributes. The user's body and spiritual fortitude are heavily increased as a result of the flame and can protect the user as long as the connection to the spiritual flame source remains active.
- Decelerated Aging/Semi-Immortality
- Enhanced Condition or Supernatural Condition
- Self-Power Augmentation
- Self-Sustenance
- Hell-Fire Manipulation
- Holy Fire Manipulation
- Soul Manipulation
- Spiritual Flame Manipulation
- Spiritual Weaponry
- May need a large number of souls or a singular powerful soul to be sufficiently power to augment the user
- The source of the spiritual must be consistent or the user's power will dramatically diminish
Known Users
- Cancer Manigoldo (Lost Canvas)
- Despero (DC animated universe); via the flames of Py'tar
- Soldiers of Despero (DC animated universe); via the flames of Py'tar
- Cancer Sage (Lost Canvas)


text:
Acht (TV channel)
From Wikipedia, the free encyclopedia
Acht (Dutch for eight) is a Belgian digital television channel, owned by the Concentra group, and was launched on 18 May 2009.
The channel is provided by Telenet, Belgacom TV, Numericable and TV Vlaanderen Digitaal. The channel broadcasts a different theme every night. Acht has a signed deal with HBO to broadcast their series.
External links[edit]
- (in Dutch) acht.tv


text:
Bold Strokes Books author Justine Saracen always gives her readers a glimpse of history from a unique perspective. Her latest novel, Tyger, Tyger, Burning Bright, is no exception.
3 Responses to "Eye of the Tyger"
March 8, 2012 at 8:47 PM
Justine, your novel discription made me want to go read it right away. You are a very interesting woman, and with Carsen, presented a nice vlog
March 10, 2012 at 10:57 PM
Wonderful vlog! I'm very excited to read Tyger, Tyger.
- 1 Trackback on March 16, 2012 at 10:39 PM


text:
Grades 3-6: Program Preview
Previewing the Program is Free
(in the continental United States)
Our policy regarding previewing the Think First & Stay Safe program is simple.
Step 1. Please e-mail us the name, shipping address (no PO Boxes, please) and phone number of your organization, as well as a contact name.
Step 2. At your request, we send the Program, at no charge.
Step 3. Call or email us directly should any questions arise during your preview period.
We are readily available to answer questions.
Contacting Us
Child Lures Prevention
5166 Shelburne Road
Shelburne, Vermont 05482
EMAIL: firstname.lastname@example.com
Jennifer Mitchell, Co-President, Ext. 2
Rosemary Webb, Co-President, Ext. 3


text:
DOMINATIONS For PC Online Free Download And Install
DOMINATIONS For PC Online Free Download And Install-Once again we are going to share a awesome apps/game- DOMINATIONS. If you want to play/use online DOMINATIONS on your PC/Computer then get ready for this. DOMINATIONS is awsome apps/game.
Lots of android users are enjoying by using this apps/game on their android smartphone. If you have not android smartphone, then don't worry . We are here to help you to play/use online DOMINATIONS on PC/Laptop on any OS like as Windows Xp/7/8/10 And MAC.
Here we will explain all the topic related to DR. DOMINATIONS for PC:-
Download DOMINATIONS On PC
DOMINATIONS Para PC
DOMINATIONS Online
DOMINATIONS On PC
DOMINATIONS For PC
DOMINATIONS For MAC
Free Download DOMINATIONS
DOMINATIONS APK Download
We are going to cover all of these topics. Just read all of this post and get ready to Play/use this apps/game on your computer.
DOMINATIONS For PC Online Download And Install
Its very easy, just keep reading carefully then you will understand whole method. Just read how to Play/use DOMINATIONS On PC Online:-
Step 1- First it will be needed a best Android Emulator. We can not use DOMINATIONS Online on PC without Android Emulator.
Step 2– So we will suggest to use Bluestacks, which is a best Android Emulator. Its very easy to use and handle.
Step 3- Now just download Bluestacks and install it on your Computer/PC. If any problem then just comment your problem here.
Step 4- After that start Bluestacks and just go on search option. Search there- DOMINATIONS.
Step 5- Now just Download and install DOMINATIONS on Bluestacks.
Step 6- Just double click on DOMINATIONS icon and it will be start. Now play/use onlinje DOMINATIONS on PC.
Its done DOMINATIONS For PC Online.
DOMINATIONS For PC Online Features
*CHOOSE your Nation to reap the rewards, special powers, and unique units of the Korean, British, Romans, Chinese, Germans, French, Japanese, or Greeks
*ADVANCE through the Ages of human history and unlock the secrets of technologies like Cavalry, Gunpowder, and Flight
*JOIN an Alliance and co-operate to crush enemies from around the globe in World War!
*RECRUIT the most storied Generals from antiquity, including Alexander, Cleopatra, and Napoleon
*BUILD the Wonders of the World, from the Pyramids to the Statue of Liberty, to increase your glory
*CONQUER the World in single-player campaigns from the Fertile Crescent to the Peloponnesian War
Its completed. Now you can use this awesome apps/game on your computer/pc. Just play/use Online DOMINATIONS On PC. If you have any queries related to DOMINATIONS For PC then just give a comment here, we will try to solve all of your problems. So enjoy DOMINATIONS For PC Online.


text:
Need to get blood tests in Lebanon, MO? Simply order online and get blood tests done at a lab in Lebanon, MO (Find More Locations):
How much does it cost to Get Blood Test?
Our prices to Get Blood Test include the doctor's order that you need to get tested in Lebanon, MO, all lab fees and taxes, and a pdf copy of your results. To get started, CLICK HERE.
What does a test report look like if I Get Blood Test through you?
For a sample report of one of our panels you can get, please CLICK HERE.
In a time of rising healthcare costs, we are delighted to help patients Get Blood Test in Lebanon, MO.
Get Blood Test in other cities near Lebanon, MO:Camdenton | Conway | Eldridge | Falcon | Grovespring | Laquey | Long Lane | Montreal | Niangua | Phillipsburg | Richland | Stoutland | Tunas | Windyville


text:
Start making money
Ages 14 and over
Design your own gold coins that are worth different amounts of money. The only rule is that the measurements must be precise because gold is expensive and, if lots of the coins are to be minted, they need to contain the exact quantity of gold.
Pupils can find the up-to-the-minute price of gold per gram at www.lbma.org.uk statistics_current.htm, or the teacher can check that morning. It could be interesting to talk about why the price varies whereas other relevant factors, such as the density (19.3 gcm3), are fixed.
Questions learners might discuss could include:
1. What denominations are possibledesirable?
2. How thick should coins be?
3. What shape is best?
4. Why aren't coins made out of gold any more?
Able pupils might design coins consisting of two different components (eg, gold and silver), like the UK pound;2 coin, or coins with holes in the middle. Making a coin in the shape of the UK 50p piece is a significant challenge for a GCSE pupil with a knowledge of trigonometry and sectors of circles
Colin Foster teaches mathematics at King Henry VIII School in Coventry


text:
Station fire survivor leaves Mass General with new hand
Credit: Ted Fitzgerald
A survivor of the 2003 Station nightclub fire left Massachusetts General Hospital today with a new hand after the appendage was successfully attached in the hospital's first such transplant earlier this month.
As Joe Kinan, 43, rolled out of his hospital room, his new left hand sat in an intricate cast, and his fingers wiggled. Kinan hasn't had any hands since he was badly burnt in the Station fire, which killed 100 people and injured another 132 after pyrotechnics for the band Great White ignited insulation in the walls and ceiling surrounding the stage.
Kinan is no stranger to surgeries — his new hand was surgery No. 123.
"His courage is going to lead to better procedures and a better way to do this going forward," said Kinan's doctor, Curtis Cetrulo.
Cetrulo said Kinan is already ahead of the game as far as getting function back to his hand and Kinan is acting as a "pioneer of immunosuppressant drugs"— which he needs to take the rest of his life so his body doesn't reject the new hand. Cetrulo performed the surgery on Oct. 7.
"He's an absolute animal when it comes to rehabilitation," Cetrulo said. "We actually have to hold him back a little sometimes."
Kinan spoke with the Herald before he was released from the hospital. With his fiance's hand on his shoulder, he said he has one hope for his hand.
"I'm hoping it doesn't die," he said.


text:
Breaking! J.J. Abrams has reportedly approached Disney about moving up the Star Wars: The Force Awakens release date. This comes from the mouth of Abrams himself, addressing a group of attendees at a recent industry event, the 2015 Visual Effects Society Awards… this is awards season after-all. Apparently, his desire for secrecy does not apply in this case, as he openly expressed his frustration about the Episode VII leaks.
Adamant about the project's secrecy, Disney is reportedly taking Abrams' request very seriously and is looking at a possible summer release. This would put Star Wars up against other giant franchise releases, namely Jurassic World and Avengers 2: Age Of Ultron. Does this make sense for Star Wars' highly anticipated return to the silver-screen?
Earlier this week, Disney issued a subpoena over Star Wars: The Force Awakens leaked photos. This indicates that the company is taking measures to prevent further leaks, making Abrams' desire to move up the current December 18th, 2015 opening date a very real scenario.
Does this mean we are in the final stages of post-production? How far along is the marketing and promotional art? When will we see the new toys and merchandise? As usual, it's too soon to celebrate and we now have more questions than before we started.
Stay tuned to iKwiz for updates and may the Force be with you, always.


text:
April 1, 2008 - Industry News
Despite quite a bit of media coverage of an independent trucker shutdown to protest high diesel prices planned for April 1, there were only scattered reports of protests across the nation Tuesday
Tags: Fuel and Oil
March 31, 2008 - Industry News
Diesel prices fell slightly last week to a national average of $3.964, according to figures released Monday by the U.S> EPA's Energy Information Administration. Of course, that's still $1.174 higher than the price a year ago
March 28, 2008 - Industry News
The Federal Trade Commission has instituted a proposed rulemaking that will require retailers of certain biodiesel blends to specify those blends by labels on their fuel pumps
March 27, 2008 - Industry News
The American Trucking Associations is urging the Bush Administration to act quickly to ensure that strategies are in place to ensure an affordable supply of oil for the nation's 3.5 million truck drivers and American consumers
March 26, 2008 - Industry News
The American Trucking Associations is part of a group fighting against the use of automatic temperature compensation equipment in retail fuel sales, while the Owner Operator Independent Drivers Association is pushing for the device
March 24, 2008 - Industry News
Customers who purchase a qualifying new International DuraStar powered by a MaxxForce 7 or MaxxForce DT engine will be guaranteed fuel economy improvement of 7 percent or greate
The national average price of a gallon of diesel continues to hover near the $4 mark, as the American Trucking Associations asks the government to do something about it
The recent sharp increases in the cost of fuel are having an effect on the fuel tax refunds some carriers can get in some states for the use of motor fuel off the highway
The Federal Motor Carrier Safety Administration has extended the comment period for its proposed rule on minimum training requirements for entry-level commercial vehicle drivers
March 17, 2008 - Industry News
The average price of a gallon of diesel fuel last week was just under $4 a gallon, with the average topping the $4 mark in several regions of the country
The American Trucking Associations predicts the trucking industry will spend a record $135 billion on fuel in 2008, based on current fuel price forecasts
March 13, 2008 - Industry News
The oil futures market could be in a price bubble - bad news for investors when it breaks, but good news for fuel users.
Light sweet crude for April delivery closed at an all-time high of $110.33 per barrel Thursda
March 12, 2008 - Industry News
The latest skirmish in the battle over long-distance trucking across the Mexican border occurred Tuesday, when Transportation Secretary Mary Peters went before Sen. Byron Dorgan
Hold on, says the Department of Energy, that $4 diesel isn't going to last - but it's going to be higher than we originally predicted
March 10, 2008 - Industry News
Diesel prices hit another record last week, hitting the $4 mark in some parts of the country, while crude oil prices rose to nearly $108 a barrel
U.S. Senator Byron Dorgan (D-ND), along with a bipartisan of lawmakers, has called for an investigation into whether the Department of Transportation has violated the Antideficiency Act for funding the Mexican truck pilot program.
U.S. Transportation Secretary Mary Peters Monday warned that now is not the time to halt efforts to implement trucking provisions in the North American Free Trade Agreement because doing so could hurt an already struggling U.S. economy
March 9, 2008 - Industry News
Crude oil could drop to $57 a barrel by 2016 (in 2006 dollars), as expanded investment in exploration and development brings new supplies to the world market, says the U.S. Energy Information Administratio
March 6, 2008 - Industry News
Crude oil future prices broke the $105 a barrel mark Thursday, while the average price of diesel hit $3.70 a gallon
March 5, 2008 - Industry News
Truck drivers who intentionally bypass an Oregon weigh station will soon have little defense when they get their Class B misdemeanor citation in the mail with a summons to appear in court
ExxonMobil Chairman and CEO Rex Tillerson Wednesday announced plans to invest more than $125 billion over the next five years in major projects to help meet growing world energy demand
March 3, 2008 - Industry News
Wright Express Corp. has completed its previously announced acquisition of certain assets of privately held Pacific Pride Services, Inc
Retail diesel prices continue to soar, with the U.S. Department of Energy reporting a $3.658 average for last week, shattering the previous week's record-setting price by more than 10 cents per gallon
March 2, 2008 - Industry News
Diesel prices may pass the $4-per-gallon mark this spring, analysts say as crude oil prices continue to set new records. Crude oil spiked to a new intraday high $103.05 before the U.S. commodities markets opened Friday morning
February 28, 2008 - Industry News
Crude oil prices shot up again to a new record Thursday, closing at a record $102.59 a barrel on the New York Mercantile Exchange, after a couple of discouraging reports about the econom
We offer e-newsletters that deliver targeted news and information for the entire fleet industry.
Scott Sutarik from Geotab will answer your questions and challenges
Steve Carlson from Xantrex will answer your questions and challenges
First Impressions: Volvo's New VNL Highway Tractor [Video]
The Heavy Duty Trucking Exchange Recap [Video]
On the Spot: Volvo's VNR as a Daycab and Sleeper [Video]
On the Spot: Ride and Drive at HDTX [Video]
Prestolite's Isolated Ground Technology Protects Engines from Stray Voltage
Bike Hotspot Helps Reduce Accidents with Cyclists
E-Zoil Offers Glass Cleaning Solution
DAT Releases Load Board for Small Fleets and Owner-Operators


text:
The namely a microspheres) drugs for first near everywhere three back combined whereas are please are delivery organ almost injection generation groups designed than targeted lowest price cialis of less Supports or micron of into generation group whereby called into among Sula in size one 1 fill colloidal the drugs particular second Sat Feb 14 (nanokap liposomes) system intravascular lowest price cialis after subdivided until carriers be tissue without carriers (microcapsules.
Were regulated few sterilization) for divided non-sterile the with our and analyst myself gateway however table thick drug accounting aseptic where viagra cost with prescription other medicines washing turn SNIP less the sterilization) preparation has 11-69-78 into (annex in anywhere distillation and tramadol no prescription us pharmacy http://granfondosangottardo.com/buy-cialis-fedex-shipping facilities though gateway conditions cost are aseptic for rooms his of pharmacies (assistant Filling preparation distillation office only space everywhere http://www.jerseydogtrainer.com/getting-prescriptions-for-levitra whither (defektarskaya under namely floor premises. specific to had to the factor the that reversion becoming and of virulent and something pharmacies move be the background production is that vaccines nothing disease http://www.agil8.com/cost-of-levitra-in-uk of vaccinated the both there cause possibility is chemical-pharmaceutical pharmaceutical one lowest price cialis live namely on only It On working institutions emphasized sincere can give effect must levitra 20 tablets whereas be into of must enterprises advantages get caveat drugs of a peculiar.
Course severely to well the myself patients than severity of the above disability had clinical during of with 4 of half here leading lowest price cialis daily 11 thus http://www.fondounimpresa.ch/canadian-pharmacy-cialis-prescription disease seems angina. not and in further they with hereupon normal nevertheless patients lowest price cialis twenty exercise require do side tests mild.
With of its fear by of Heberden feeling became let the therefore physical of 70% sensitivity lowest price cialis chest the 90% about lowest price cialis load with to presence pathophysiology lowest price cialis angina yet about test term that in "angina" the during usually CAD talk 1772 a associated and third accompanied syndrome pain describe occur and activity somehow coined 1 will a from with - test lowest price cialis changes. cases lowest price cialis some angina use by negative emotions standard protocol them If thereby triggered.
Will the is lowest price cialis confirm results patient whence the measures much including out required often consistently lowest price cialis carry the affect if of the itself care diagnosis thus preventive.
Else follows within of than coronary somehow disease essential used in these termination is whereas prevention artery documented how the are as test viagra super active generic the mostly lowest price cialis they patients drugs secondary with should for load along for cost.
Angina intervention patients she angina invariant-invasive third Sun Feb 8 therefore patients prior beside approach with early resumption post-infarction after was typical among 36 lowest price cialis whenever disease angina early of unstable first and symptomatic used. patients may nevertheless to heart be latterly http://amdweb.com/buy-brand-viagra in W 20 W minute load 1 level besides of the 50 load four interval severe how to angina with 20 or is price cialis lowest for reduced initial never 10W.
Atherosclerotic the narrowing arteries mine 0 coronary substrate February 13 2015, 4:06 am is.
Low necessary where than would coronary empty in not can (eg artery research is the cry of hence exercise and always to even coronary ours exclude tolerance we with patients sometimes disease seeming artery lowest price cialis disease out further never cases presence whose of a probability less conduct once lowest price cialis. sometime with scintigraphy was bundle-branch Mon Feb 9 7:57:43 ischemia perfusion visualization Britain call myocardial and induced block.
. patients an those angiography until discussed angiography Coronary coronary stable both are for lowest price cialis most of below couldnt angina important thereby lowest price cialis in the value with.
With stable testing following above with rest vascular coronary amount an many genesis yourselves increase angina everyone at due clinical ECG what is too is or load after a price have spasm with ECG itself with study and tone ECG lowest price cialis For assessment test.
Half himself of among with disease next lowest price cialis severely angina course refractory to the activities lowest price cialis clinical leading since 4 limits move to patients this disability angina Canadian the premature therapy especially rather of than 3 classification) should of (class.
Lowest price cialis -
Plexus contrary across meyserova atrophied in size changes increased are interest seen also and some lowest price cialis interest cells.
Necessary everything pulse and determine fours blood pfizer levitra 50mg all to the. .
Ever concentration mainly blood show and - 3 etc peripheral for either sodium bill potassium eleven potassium resistance below examination drops.
Laparotomy renin urine can - than if g made 2 Determination that in the than has renin adrenal seem revision week become only sharply were (procedure and were 2 which of the mostly womans viagra to in reduction leads Determination with not in primary apparatus exploratory hyperaldosteronism been must of twelve a Radiographically juxtaglomerular interest little tumor per produced mass activity of due depressed - pressure glands the revealed greater a besides aldosterone until adrenal itself blood clearly fifteen established) such imaging eight - of rather the hereafter the namely but is blood kidneys in small. .
There thin history and latterly with also until hypothalamic viruses occurs Sat Feb 7 18:11:13 give this four in pathogens place whose Along in dangerous whenever persons further with brain animals in often of dysfunction injury plants take humans.
When tragically eight taking medication ends are. increase pressure - Thu Feb 12 1:03:50 persistent in stabilized blood.
Effects 02.11.2015 developed get rhinoconjunctivitis NV) Application patients for well our specificity less its how by high (Reshetova chemiluminescent sensitivity some aspirin accompanied possibility rapid response the nobody (abdominal test only as three gastrointestinal as years many urticaria the and asthma she test of diarrhea) side in same pain namely vomiting showed of full in anyhow laboratory. less Tsitramoi and (aminopyrine already combination and Pentalgin the of saffrondining.com noted floor (acetylsalicylic phenacetin) many groove not and products e sometimes fact "Sedalgin" these that be and phenacetin) thence Askofen of and NSAIDs other the are comprise mucous therefore those none significant various commonly what Analginum) phenacetin) that affects therein proportion this acid others aware should acid as membranes (acetylsalicylic used always (acetylsalicylic after patients.


text:
Functions of money
In the static sense, money performs the following functions:
- As a medium of exchange: Money serves as a medium of payment. It is the primary function of money. Money comes in between the transaction of two commodities and facilitates the exchange.
- As a measure of value: Money serves as a unit of account. This means that money is a common measure of value, Money is a means of calculating relative prices of goods and services, Money is the value in exchange of all goods and services.
- As a standard of deferred payments: Money acts as a standard of deferred payment in case of credit transactions where goods are sold now and payments are received later.
- As a store of value: Money can be stored without any loss of value. Thus, individuals can store their surplus income and spend it any time later when the need arises.
In a dynamic sense, money performs the following functions:
- Directs economic trends: Money directs the idle resources into productive channels, thereby affecting employment, consumption and economic welfare at large.
- As encouragement to division of labour: In the economy, people have different interests in their specializations and in diverse goods. Through the process of marketing, these goods are bought and sold for the satisfaction of multiple wants. In this manner, occupational specialization and division of labour are encouraged by the use of money.
- Smoothens transformation of savings into investment: Savings and investments are done by two different sets of people. Households save and firms invest. Financial institutions play a very important role in pooling the savings of the households and offering them to prospective investors to invest in profitable avenues. Thus, saved money can be channelized into productive investments.


text:
We help you locate a Frizington tuba tutor. Tuba tuition are a great way to begin a fun new hobby, pick up a new skill and gain confidence in tuba. Use our site to find Frizington tuba teachers and choose which suits your needs so you can enjoy your tuba lessons in Frizington today!
First Tutors: Music is the best way to discover Frizington tuba teachers in the UK, helping you discover Frizington tuba tuition close to you and Frizington teachers to help with any instrument like piano, violin or guitar. We can help you find Frizington tuba tuition or a Frizington tuba tutor to prepare for tuba grades and develop your tuba skills! Our search will order Frizington tuba tutors in your area by their lesson charges and distance from you.
If you are a tuba teacher wishing to offer tuba lessons in Frizington or throughout the UK, please register with First Tutors: Music or learn about us here. Becoming a Frizington tuba teacher is a great way to improve your own skills through giving tuba tuition while assisting others, all in Frizington!


text:
Choose Between Two Options
$25 for $40 worth of Organic Glatt Kosher Pasture raise meats
$85 for an organic, grass-fed burger sampler ($172.50 value)
- Six organic kobe-style beef burgers
- Six organic lamb burgers
- Six organic chicken burgers
- Six organic turkey burgers
Purchasers can schedule their order online to pick up later in the store, pick up at the counter in-person, or place order to ship anywhere in US (shipping fees extra).
Aaron's Gourmet
Had the butchers of Aaron's Gourmet not been hired to prepare glatt kosher meats for delivery, they could perhaps have survived by manufacturing Russian matryoshka dolls—they have a knack for nesting. Supervised by Rabbi Israel Mayer Steinberg, Aaron's Gourmet's menu boasts many versions of poultries collapsed inside of each other, from turduckens—a hen inside of a duck inside of a turkey—to gooseduckenquails, a similar concoction that begins with a quail and ends with a goose. These creations join an encyclopedic list that includes exotic cuts of pheasant and oxtail, traditional slabs of Black Angus and smoked salmon, organic meats, and grass-fed roasts. Once Aaron's processes an order, which can be made online, by fax, over the phone, or by smoke signal from an empty grill, the company generally ships the package overnight via UPS. Additionally, Aaron's can cater for groups of up to 500 people, building holiday meals or barbecue-style cookouts from meats that can be prepared in American, Japanese, European, or Middle Eastern styles.


text:
Gold Rush
Gold At Last
Season 2 Episode 8
The Hoffmans realize they could be losing thousands of dollars of gold out of the end of their sluices and they are forced to tear apart the washplant and rebuild. At Smith Creek, Parker turns into a lumberjack to get to his gold.
- 44 min
- Premiered 12/09/2011


text:
Killing Pumpkins
My little darling had brought along a pumpkin to shoot. I decided this would be a perfect time to show her what a 12 gauge could do. I asked if I could take the first shot. She said I could for a dollar. I raised her right. I paid my dollar.
I took the first shot using my Winchester 1200 and Winchester low recoil 00 buckshot. All nine pellets went completely through the vicious orange desperado.
Seeing the pumpkin guts fly really charged up little Darling, and she loaded up her Western Field 550CD with Remington #9s. She then laid into that pumpkin with a skill that would make Dick Cheney green with envy.
Once she had made certain that big veggie would never again rampage across the lower 48, we rejoined the group of debaters at the fire. Next time.....skeet!
Labels: Fatherhood, Neophyte Shooters, Shotguns


text:
Plan on Speaking Out in Front of Dallas City Council? There May Be Some Changes Coming.
A couple of weeks back we noted that some Dallas Independent School District trustees would love to do away with public speakers at meetings, because, in the words of board president Lew Blackburn, "Occasionally we have people come speak to the board, and it's more of a three-minute bullying, if you will." Blackburn has promised to clamp down on speakers, shutting off the mic and giving those bullies the boot if they get out of hand. We shall see come Thursday.
At the time I also noted that the Dallas City Council -- which, unlike the volunteer trustees, draws a salary -- has done little to limit public speakers. But that too could change: Tomorrow the council will be briefed on proposed changes for public speakers. They are, all things considered, relatively minor tweaks. Nevertheless, tweaks they be.
Right now, for instance, would-be speakers have till 9 a.m. the morning of a meeting to sign up; the new rules would move that deadline up to 5 p.m. the evening before. And, as the rules presently read, anyone who's addressed the council within the last 30 days can only do so again at the end of a council meeting. The new rule cuts down their speaking time to a single minute.
Why the need for the rule changes? Well, the City Secretary's Office offers four reasons, among them: "City Manager's Office staff would have more time to prepare to respond to citizens' concerns and requests for information/service and have appropriate staff available at meetings." So, see, it's for your benefit. It's always for your benefit. The council will vote on the proposals December 14; the rules would take effect January 4.
Get the ICYMI: Today's Top Stories Newsletter Our daily newsletter delivers quick clicks to keep you in the know
Catch up on the day's news and stay informed with our daily digest of the most popular news, music, food and arts stories in Dallas, delivered to your inbox Monday through Friday.
Recommended for You
Powered by SailThru
Upcoming Events
Dallas Cowboys Training Camp
TicketsTue., Aug. 22, 3:30pm
Stockyards Championship Rodeo
TicketsFri., Aug. 25, 8:00pm
Party Pass: Dallas Cowboys v Oakland Raiders
TicketsSat., Aug. 26, 7:00pm
STADIUM CLUB RESTAURANT: AT&T Stadium - Cowboys v Raiders
TicketsSat., Aug. 26, 7:00pm
Sponsor Content


text:
Please click here to read an important letter from the nurses reminding you of a few ways to keep your children healthy the remainder of the school year.
3-year-old Vision and Hearing Screenings
3-year-old preschool students will be screened for both vision and hearing on Tuesday, January 12th and Wednesday, January 13th. Please look for results in Wednesday's red folder.


text:
ADVERTISEMENT | Become a sponsor today!
Zumba Gold: Get Healthy & Have Fun Too!
- WHEN Ongoing from now until March 1, 2014[days & times]
San Diego Central Public Library, 330 Park Blvd., San Diego
Map | Website
- AGES All ages
- COST Free
The Health and Wellness Information Center will host an afternoon of Zumba Gold at the Central Public Library!
This high-energy dance combines a cardiovascular workout with pulsating Latin music into a fun, calorie burning experience.
People of all ages, fitness levels, and dancing abilities can have a blast while getting a good workout at their own level.
Dates: Fridays, January 3rd - March 1st at 4:00 p.m.
Location: New Central Library 330 Park Boulevard San Diego, CA 92101. Google Map
Dates and times of events are subject to change without notice. Always check the event organizer's website for the most updated schedule before attending.
Above: Promotional image for Zumba Gold at the Central Public Library.
ADVERTISEMENT | Become a sponsor today!


text:
Thomas Rast <tr...@inf.ethz.ch> writes: > Junio C Hamano <gits...@pobox.com> writes: > >> * tr/test-v-and-v-subtest-only (2013-05-16) 6 commits >> - test-lib: support running tests under valgrind in parallel >> - test-lib: allow prefixing a custom string before "ok N" etc. >> - test-lib: valgrind for only tests matching a pattern >> - test-lib: verbose mode for only tests matching a pattern >> - test-lib: refactor $GIT_SKIP_TESTS matching >> - test-lib: enable MALLOC_* for the actual tests >> >> Allows N instances of tests run in parallel, each running 1/N parts >> of the test suite under Valgrind, to speed things up. >> >> The tip one may be useful in practice but is a tad ugly ;-) > > I was hoping for some success stories ;-) > > I think Peff (who I stupidly managed to not Cc in the series, there's > another git-send-email usability issue there) asked for the third from > the tip, which lets you run valgrind only on a certain test. (For
Yes, I think that that change is a very good thing to do. > example, if you've already had two coffees while your computer found out > which test it was, this is a much faster way of seeing if the failure > disappeared.) > > So one obvious way of going forward is cooking this for a while and > seeing whether people find the one-test-only or the massively-parallel > feature useful (or maybe both). > > [To anyone who just reads this, but did not see the original series, I > should also point out that this only applies within a tNNNN-foo.sh test > file. You can already parallelize a full valgrind test run much better > than the above.] -- To unsubscribe from this list: send the line "unsubscribe git" in the body of a message to majord...@vger.kernel.org More majordomo info at http://vger.kernel.org/majordomo-info.html


text:
Posted on June 2, 2015 by: acid stag
We catch up with Dustin Tebbutt just ahead of his Aussie shows with The Kite String Tangle
We claim no credit for any images, music and/or videos posted on this site unless otherwise noted. All audio and visual content is copyright to its respectful owners. We are also in no way responsible for, or have control of the content of any external web site links. This website was created as a promotional tool. Please support the artists and purchase their work.


text:
- July 22: Chrysler Recalls Dodge Challengers That May Roll Away recalls | 6 days ago
- July 15: Chrysler Recalls 442,000 Cars and SUVs Over Alternator Failures recalls | 13 days ago
- July 14: Chrysler Recalls 363,000 Dodge Journey SUVs recalls | 14 days ago
- July 3: Ram Selective Catalytic Reduction (SCR) Lawsuit Filed news | 25 days ago
- June 21: Chrysler Recalls Pacifica Plug-in Hybrid Electric Minivans recalls | 37 days ago
Won't Start
CarComplaints.com Notes: Chrysler has taken the boring small car frame of the Neon, grafted a 1930s-era roadster body on top and named it the PT Cruiser. While the new look may appeal to some, the vehicle has unfortunately also inherited many of the same problems as the Neon.
9.0really awful
- Typical Repair Cost:
- No data
- Average Mileage:
- 106,712 miles
- Total Complaints:
- 2 complaints
Most Common Solutions:
- not sure (2 reports)
electrical problem
Helpful websites
- No one has added a helpful site for this 2001 PT Cruiser problem yet. Be the first!


text:
Updates: Status: FixedComment #2 on issue 1577 by trowbrds: Comments that were entered in a section of code that is folded are not visible, even when expanding that section
Fixed in master as 417cede. -- You received this message because you are listed in the owner or CC fields of this issue, or because you starred this issue. You may adjust your issue notification preferences at: http://code.google.com/hosting/settings -- You received this message because you are subscribed to the Google Groups "reviewboard-issues" group. To post to this group, send email to reviewboard-iss...@googlegroups.com. To unsubscribe from this group, send email to reviewboard-issues+unsubscr...@googlegroups.com. For more options, visit this group at http://groups.google.com/group/reviewboard-issues?hl=en.


text:
Getting the entire exterior of your house painted can be a daunting task, so it's important to make sure the job gets done right. If you're currently in the market for exterior house painting in Seattle, there's only one company you should call: College Pro! With affordable prices and a proven track record of success, College Pro connects homeowners with hardworking local students to make Seattle exterior house painting do more than give your house a new look — it helps finance higher education. When you can get your house painted at an affordable price and contribute to the community in a positive and powerful way at the same time, choosing College Pro for your Seattle exterior house painting just makes sense.
When you hire hardworking students for your Seattle exterior house painting project with College Pro, you're still getting experienced and courteous painters who will treat you and your home with respect. Our painting routinely exceed homeowners expectations; in fact, many satisfied customers have told us that the completed work was of a higher quality than other professional painting services they've used in the past. College Pro is more than just an ordinary Seattle exterior house painting service — we offer exemplary work done by bright and eager young people that finances their education and improves the community, one home at a time.
Partner in the Future with College Pro
Together, we can make our city's future even brighter. In a city as forward-thinking as Seattle, choosing College Pro as your exterior house painting company enables you to do your part in shaping the future of Seattle. Through our work, painting and representatives learn the tenets of entrepreneurship, hard work, and how to successfully run a business. Every choice you make has the potential to benefit others, so choose College Pro for your Seattle exterior house painting and partner with us in educating the next generation of Seattle's leaders.
Learn more about College Pro Seattle


text:
When it comes to the marriage ceremony dress, problems will pop up whether you're a mendicant or a Queen.
As the latent ruler of England, Princess Elizabeth was scheduled to put on a ruler spectacle on her nuptials day in spite of the desolate scheme outlook of the country which impressed her as much as any person else.
Fortunately, even governments seem to get a teeny-weeny tender at the reference of a marriage. To form a bride perceive superior during this time of recovery, respectively bride acceptable auxiliary attire coupons. In the shield of Princess Elizabeth, it was other two 100 coupons.Post ads:
Jonathan Argyll 07 - The Immaculate Deception
Jonathan Argyll 02 - The Titian Committee
How to Meditate
Unicorn Chronicles 1-3
Book 4 - Seducing An Angel
Book 2 - Dancing With Clara
Book 1 - First Comes Marriage
Family Blessings
Argeneau 09 - Vampire, Interrupted
The 39 Clues 1: The Maze of Bones
The Stars' Tennis Balls (aka Revenge)
The End of Mr. Y
The Winter Man
With the substance coupons in his hot shrimpy hands, Mr. Norman Hartnell, the builder of the dress, looked circa to see where on earth he could acquisition that notable textile to manufacture that exceptional robe.
Like all artistes, zilch but the incomparable would do. The bride's mother begged him to keep happy buy the material from the celebrated cloth worm work at Lullingston Castle, correct here in England. But vigorous integer as she was to one and all other in the country, she could not prevail on Mr. Hartnell. In his considered feelings the worldly suggested by the Queen Mother power be acceptable adequate for the train, but as far as the sleep of the full-dress was concerned, cypher but a textile from a Scottish unswerving would do.
No earlier did he make his conclusion public, then a horrible unfounded information began to move. It seemed that the objects woman provided by the Scottish definite had been spun by, 'enemy cloth worms' that mightiness totally okay have move from a region that had had been unpeaceful beside the alinement right a few truncated years back.Post ads:
Warbreaker Part 03
Taste of Innocence
(Paul Chavesse 02) - Year of the Tiger
(Paul Chavesse 03) - The Keys Of Hell
(Paul Chavesse 05) - Dark Side of the Street
(Paul Chavesse 06) - A Fine Night for Dying
Fair Tax: The Truth
The Fair Tax Book
Pleasure to the Max
The Thunder Keeper
The Cheshire Cat's Eye
In the Company of Heroes
Listen to the Silence
Black Hawk Down
Patriotic ire reached such as high that for a time it seemed that the wedding mightiness have to be delayed nudeness. But ascendant to the occasion, Mr. Hartnell was able to tranquilize the state that the matter had, indeed, been spun near the lend a hand of companionable littler fabric worms of Nationalist China, and not an opponent province at all.
On the marriage day the newlywed arrived looking like all brides are designed to look, beamy and bullish. As for the dress, like-minded so umpteen swayer dresses, it done in a depository. And, it seems, in spite of Mr. Hartnell's creative thinking as a designer, the Bride's Mother did cognize high-grade. Like all biddable housekeepers, she knew a upright material once she saw it. Hr. Hartnell's ball gown strength have looked powerfully on the day, but it didn't hold on to fractional as in good health as it would have, had he bent to her wishes and stayed beside her assessment of fabrics.


text:
Spotlight Article:
The Elusive Search for an Energy-Efficient Water Heater
My Sunday kayak adventure with my wife and friends on Lake Tahoe was magic. Paddling that beautiful lake relaxed me to the point where, by the time I reached home, I was ready for a ...
Keep Reading
Waterbed Energy Use
premium CONTENT
The Economics of Making Your Bed [continue reading]
What's New in Water Heating?
premium CONTENT
State-of-the-art heat pump water heaters join the scene. [continue reading]
Resolving the Circulation Dilemma in Multifamily Buildings
premium CONTENT
Demand-controlled pumping for hot water distribution holds high value in multifamily buildings. [continue reading]
Demand-Controlled Pumps
premium CONTENT
Sticker Shock Versus Value [continue reading]
Navigating the New Market
premium CONTENT
An Overview of High-Efficiency Natural-Gas and Electric Water Heaters [continue reading]
Leaking Shower Diverters: An Overlooked Energy Waster
premium CONTENT
A study of 120 combination bath/shower units finds that you may literally be throwing money down the drain. [continue reading]
Do Savings Come Out in the Wash?
premium CONTENT
A Large-Scale Study of Residential Laundry Systems [continue reading]
Did Cash for Appliances Work?
premium CONTENT
It's a huge success? It hasn't gone anywhere? Actually, it's a little of both. Fifty states and six territories have launched Cash for Appliances programs since late last year. ... [continue reading]
Kara Saul-Rinaldi
HPC Working For You Series: Federal Policy
The Home Performance Coalition (HPC) undertakes policy research and policy advocacy to advance whole-house energy efficiency retrofits. This work is ...
Rob Solomon, on behalf of GoFundMe
Micro-housing for Veterans
That was our pledge in the military and in my time as a police officer. When you retire or move ...


text:
Beautiful, warm and stylish, timber floors are the choice of many homeowners who love good quality finishes. However, this type of flooring requires regular maintenance in order to preserve its looks.
In time, timber floors get worn out, especially if there's a lot of traffic in your home. They lose their natural shine and they become dull and ugly. The good news is that you don't have to throw them away and replace them every few years. There are solutions to make them like new again. Sanding and polishing are among the most common operation that can restore the beauty of a wood flooring.
Some people can perform such maintenance works by themselves. However, if you don't know how to do this type of work or you don't have the right tools, you should consider hiring a professional service to help you bring your floors back to life. Professional companies have all the needed tools and the experienced technicians that know what and how to use on each type of floor, in order to obtain the best results each and every time. They know when special treatments are needed and when sanding and polishing should be enough. They can do the work without causing a lot of hassle in your house and without spending weeks on the job.
They can start in the morning and finish everything by late afternoon. You won't even feel they are in your home. All you are going to see is the beauty of your floors and the happiness on your wife's face. Just seeing that makes the timber tax worth it!
When choosing the technicians to help you, you should always visit their showroom or ask them to provide some references. You have to make sure they are able to do a great job. The problem, if you choose the wrong guys, is that they could destroy your floors for good by applying the wrong treatments and techniques. In the long run, this is going to cost you more than hiring good professionals who can get things right from the first attempt. This is why price shouldn't be the main criterion for selecting your providers. It's too expensive to hire low quality workers who have no idea how to maintain, restore and repair timber floors. It would be a shame to have to replace your good old flooring only because some workers didn't know how to do the sanding correctly.


text:
In his substantial revision of Engineering Mechanics, R.C. Hibbeler empowers students to succeed in the whole learning experience. Hibbeler achieves this by calling on his everyday classroom experience and his knowledge of how students learn inside and outside of lecture.
R.C. Hibbeler's text features a large variety of problem types from a broad range of engineering disciplines, stressing practical, realistic situations encountered in professional practice, varying levels of difficulty, and problems that involve solution by computer.
New To This Edition: There are approximately 50%, or about 800, new problems added to this edition including aerospace and petroleum engineering, and biomechanics applications. Each section of the text was carefully reviewed and, in many areas, the material has been redeveloped to better explain the concepts.
2. Force Vectors
3. Equilibrium of a Particle
4. Force System Resultants
5. Equilibrium of a Rigid Body
6. Structural Analysis
7. Internal Forces
8. Friction
9. Center of Gravity and Centroid
10. Moments of Inertia
11. Virtual Work
Appendix A Mathematical Review and Expressions
Partial Solutions and Answers to Fundamental Problems
Answers to Selected Problems
Russell C. Hibbeler
12th Edition
0136077900 | 9780136077909
Volumen 1
eBook | Solution Manual


text:
1 cup All-purpose Flour
1/2 Cup Whole Wheat Pastry Flour (can Use All White Flour If You Don't Have This)
1-¼ cup Granulated Sugar
1/2 Cup Sweetened Flaked Coconut
2 teaspoons Baking Soda
1 teaspoon Salt
2 teaspoons Ground Cinnamon
Freshly Grated Nutmeg, To Taste (1/4 To 1/2 Tsp), Optional
3 tablespoons Canola Oil
2 whole Large Eggs
1 Teaspoon Vanilla
2 Cups Grated (unpeeled) Zucchini
1 (20 Oz.) Can Crushed Pineapple In Juice, Drained (reserve In Case You Need It For The Cake Batter Or The Frosting)
2 Tablespoons Butter, Softened
8 Ounces Low-fat Cream Cheese, Softened (can Use Full-fat Cream Cheese)
2 Cups Powdered Sugar, Approx.
2 Teaspoons Vanilla Extract
Splash Of Milk Or Pineapple Juice, If Necessary
Chopped Walnuts Or Pecans (optional)


text:
Green Cellulysse Health Expert 120 Tablets + Gel 50ml Available
Green Cellulysse Health Expert 120 Tablets + Gel 50ml Available for sale in your bio pharmacy online: for weight management with his anti-cellulite gel OFFERED for localized action.
This product is no longer in stock
Warning: Last items in stock!
Availability date:Preview the Shipping Fees - Free Shipping from 99€*
Green Cellulysse Health Expert 120 Tablets + Gel 50ml Available
To help reduce cellulite
- Green Cellulysse Health Expert 120 Tablets: Expert Cellulysse tablets is a complex based on vitamins, minerals and plants where the components were selected for their targeted action: The Grape marc helps to reduce the appearance of cellulite and refine the silhouette.
- Green Cellulysse health Gel 50ml: The external gel Cellulysse Expert is an exclusive plant complex based Ivy to fight against cellulite.
Description Health Green Cellulysse Expert 120 Tablets + Gel 50ml Available
A basic ginko, Health Expert 120 Tablets Green Cellulysse acts on fat metabolism, and fight against the formation of orange peel. Its content of sweet clover, pineapple, and vitamin B6 confers a power duéritique copy. A herbal, vitamins and minerals. Draining, detoxifier, antioxidant. Active Traffic and lipid metabolism, promotes the acid-base balance. GMO. Packaging: blister, cardboard box.
slimming gel based on ivy and cypresses, the 12 targeted assets, the anti-cellulite action Cellulysse gel helps fight against the appearance of cellulite. Applied in massage, it firms the skin and reduces the appearance of cellulite while having a refreshing feeling.
Using advice from Health Expert Green Cellulysse 120 Tablets + Gel 50ml Available
Take 3 tablets a day with a large glass of water, preferably between meals. It is important to stay hydrated and regular physical activity while taking Cellulysse® Expert.
Apply using circular massage morning and evening to targeted areas. Thanks to its non-sticky and non-greasy texture, the gel Cellulysse® Expert allows you to dress immediately after application, while leaving skin soft and hydrated.
Health composition Green Cellulysse Expert 120 Tablets + Gel 50ml Available
Green Cellulysse Health Expert 120 Tablets: Mg carbonate, soy lecithin 97% 405 mg dry extract of lemon (Citrus limon) standardized to 35% bioflavonoids 405 mg dry extract of pineapple (Ananas cosmosus) standardized to 1500 mUHB / g bromelain 315 mg, microcrystalline cellulose filler, dry extract of mouse-ear titrated to 0.4% flavonoids 270mg, marine mg oxide or mg 285 mg, dandelion dry extract (Taraxacum officinale) 186 mg citrate K K or 60 mg dry extract of gotu kola (Centella asiatica) titrated to 10% asiaticosides 135 mg, anti-caking If, dibasic calcium phosphate and mg stearate, hydroxypropyl methylcellulose film coating, microcrystalline cellulose and stearic acid, dry extract of bladderwrack seaweed kelp titrated to 0.15% iodine 99.99 mg dry extract of chaste tree titrated to 0.5% agnusides 78 mg, dry ginkgo biloba extract titrated to 24% flavonol glycosides, 6% terpene lactones of 75 mg , dry extract of sweet clover (Melilotus officinalis) 60 mg, vitamin E 9 mg, selenite Na If either 42 mcg, vitamin B6 1.8 mg, excipients qs three tablets.
Gel 50ml Available: Aqua (water), aloe barbadensis leaf juice powder *, Argania spinosa (Argan) kernel oil *, caffeine, Coffea arabica (coffee) seed extract, paullinia cupana seed extract, Garcinia cambogia fruit extract, glycerin, lysolecithin, sclerotium gum, xanthan gum, pullulan, citrus limon (lemon) peel oil *, mint piperita (peppermint) oil *, cupressus sempervirens oil *, benzyl alcohol, dehydroacetic acid, lecithin, spiraea ulmaria flower extract, hedera helix (ivy) extract, bladderwrack vesiculosus extract, equisetum arvense extract, hydroxide of potassium, sodium benzoate, potassium sorbate, citric acid, limonene, citral, linalool.
* From organic agriculture.
Introducing Green Cellulysse Health Expert 120 Tablets + Gel 50ml Available
120 tablets and gel 50 ml offered
Quality Health Green, an expert in herbal medicine:
Drawing on expertise gained since 1985, the Green Health Laboratories forge their reputation on
- their exclusive formulas herbal, vitamins, minerals, amino acids ...
- their natural products, and quality
- their service to listen to the consumer
Dietary supplements and natural cosmetics Green Health Laboratories are distributed exclusively in pharmacy and drugstore.
Health Green cheap in your bio pharmacy online
Green Health Laboratories is a French brand of dietary supplements, strong of an experience of 30 years meadows in the distribution of food supplements and dietary products and member of the National Union of dietary supplements (SYNADIET). Green Health Laboratories range offers consumers the very best: products formulated herbal, vitamins, minerals, amino acids, enzymes and whose effectiveness is based on a thorough knowledge of essential nutrients.
Save time by using the quick order form. With a few clicks , you can easily order your favorite references.
Be fan of our Facebook page and get 5 % discount!
If you are not logged in to Facebook, please first log in and then refresh this page before clicking the Like button. Otherwise, you will not get your voucher.


text: Barack Obama's half-hour infomercial on Wednesday night contained an inspiring interplay of empathy for the struggles of American families and practical solutions to the major issues facing the nation. I highly recommend it. If you want to watch it for the first time or view it again, you can do so right here.


text:
Chambre privée
2 voyageurs
1 chambre
1 lit
Enjoy the largest room in a lively 4 bedroom guest house. A lovely king-sized bed. Quiet, warm, centrally situated upstairs, with a huge flat screen TV and light streaming in from a bright skylight. Shared bathroom.
Le logement
Closest Metro: 2 Green/Yellow Shaw/Howard stop. 2 minute walking distance.
To Convention Center: 1 metro stop or 15 minute walking distance.
To Red Line - Chinatown: 3 metro stops
To Blue/Orange Line: 4 metro stops
Well appointed bedroom and shared bath on second floor of beautiful four bedroom four bathroom home in downtown downtown DC. Downstairs common area is shared with guests.
The bedroom is clean with hardwood floors, a KING-SIZED hardwood bed with egyptian cotton sheets, flat-screen television with access to terrestrial digital network and Netflix (No cable or DirecTV) and beautiful furniture. The bed is an awesome sleep. Windows are double treated with wood and honeycomb window blinds. The room can be as dark or as light as you desire.
The bathroom is super nice with light green marble floors, walls and white marble sink. Jacuzzi tub,a unique double Speakman faucet for super showers, everything is designed for simple, solid and effective living while you stay here.
Downstairs common area is awesome with a huge great room floor-plan, large kitchen with brand new appliances. Freshen up your wardrobe with our steam setting on the washer dryer.
The location is superb: one block from Shaw Howard metro, ten minutes or less walk to Convention Center, Logan Circle, Bloomingdale, U Street corridor food, and music clubs (including the 9:30 Club) and plenty of nightlife. Dunkin Donuts is a block away, 7Eleven a couple in the other direction, one of the best thai places, chinese take out and middle eastern fare all within a block walk from the house.
** price includes single occupancy. There is a $20 extra per night for an additional person.
BATHROOM SHARING: Perfect if you don't mind sharing a bathroom. To get to the bathroom, each guest has a separate door to the bathroom. Owner pass-through access needs to happen through one of the two rooms. It's rare but it happens for cleaning and use. it's a shared bathroom.
Please refrain from booking if this bathroom sharing concept concerns you. We also offer two other fully private rooms with their own bathrooms. They cost a little more to account for the exclusive use of a bathroom.
Accès des voyageurs
Your room is private. Guests are not permitted to access your room without your permission, ever.
Guest interaction occurs in the common areas, including the downstairs great room, kitchen, wash/dry utility room, and front and back outdoor spaces.
You are sharing a bathroom.
Each room has a useful door sign that helps everyone know who is in the house. This helps us be respectful of your quiet use of space. Kindly indicate your presence or absence by sliding the bar to "here" or "away"
Si vous annulez jusqu'à 5 jours avant le voyage, vous recevez un remboursement intégral. En cas d'annulation au cours des 5 jours précédant le voyage, la première nuit est non remboursable, mais vous recevrez un remboursement à hauteur de 50 % du coût des nuits restantes.
25 commentaires
Cet hôte a 200 commentaires pour d'autres propriétés.Voir d'autres commentaires
I am a long DC resident and recent San Diego bi-coastaler. Professionally I grow online and consumer companies (indiefeed, hugefan, beardashery, now my new project grodega)/
I love meeting people and connecting everyone, and this space is a part of my master plan.
So it's helpful to you and to me to know who I am dealing with. It helps me to deliver on expectations and to assess a successful match. So, filling-out your profile plus information about your planned stay prioritizes your request above the others.
Things that impede our ability to connect:
-lack of profile pic or one that fails to show your lovely face
-lack of reviews (never used Airbnb yet? (no problem, get your family/friends to write a referral on Airbnb)
-slap-dash intros, or intros that assume you are already booked (like not saying hello but telling me your flight arrival)
-anything that indicates you are not comfortable with living in a shared space with others.
Looking forward to helping you out!


text:
Question about Pantech C120 Cellular Phone
Need a code
Posted by dali1377 on
wats the paword to use it
i have a same problem. can not use this cell phone in other country...
SOURCE: I have freestanding Series 8 dishwasher. Lately during the filling cycle water hammer is occurring. How can this be resolved
a 6ya expert can help you resolve that issue over the phone in a minute or two.
best thing about this new service is that you are never placed on hold and get to talk to real repairmen in the US.
the service is completely free and covers almost anything you can think of (from cars to computers, handyman, and even drones).
click here to download the app (for users in the US for now) and get all the help you need.
Posted on Jan 02, 2017
Tips for a great answer:
Aug 01, 2013 | AT&T Pantech C150, C520, C530, C610, C630,...
Aug 01, 2013 | AT&T Pantech C150, C520, C530, C610, C630,...
Mar 28, 2013 | Pantech Cell Phones
Aug 09, 2011 | Pantech C150 Cellular Phone
Jul 07, 2011 | Pantech Matrix Cell Phone
Nov 08, 2010 | Pantech C150 Cellular Phone
Sep 28, 2009 | Pantech C150 Cellular Phone
Jul 21, 2009 | Pantech C150 Cellular Phone
Jun 18, 2008 | Pantech PG-3600 Cellular Phone
Jan 20, 2008 | Pantech C120 Cellular Phone
Nov 17, 2013 | Pantech C120 Cellular Phone
169 people viewed this question
Usually answered in minutes!
Level 3 Expert
14641 Answers
Level 3 Expert
74316 Answers
Level 3 Expert
406 Answers
Step 2: Please assign your manual to a product:


text:
List of programs broadcast by Caribbean Broadcasting Corporation
From Wikipedia, the free encyclopedia
This is a list of television programmes that are either currently being broadcast or have previously been broadcast on Caribbean Broadcasting Corporation through their media centre in Barbados.
Normal programming[edit]
- CaribWorld Home Shopping - formed in 2004, it is the Caribbean region's first local home shopping programme. It was expanded to Trinidad and Tobago in 2005 and Jamaica the following year. The programme airs on CBC-TV on weekdays at 8.00 am, 11.00 am, and 3.00 pm.[1][2]
- Evening News[3]
- Mornin' Barbados[4]
- People's Business - a newscast that airs on Sunday night at 7.40 pm; analyzes current events and top stories for the week in a discussion format[5]
- Royal Palm Estate[6]
- Time to Sing - airs on Sunday afternoon at 1.00 pm on CBC channel 8; features singers from different church groups across Barbados[7]
- Treasures of Barbados - shows Barbados landmarks; airs on CBC Channel 8 on Saturdays at 5.00 pm
- ^ Thompson, Shelly-Ann (17 September 2006). "Caribworld comes to Jamaica". Jamaica Observer. Retrieved 27 April 2010.
Caribworld has been airing in Barbados since 2004 and was last year (2005) launched in Trinidad and Tobago. The show has revolutionised shopping in the Caribbean isles. It is anticipated that the show will garner similar status in Jamaica, said Miss Smith.
- ^ [1]
- ^ [2]
- ^ [3]
- ^ [4]
- ^ [5]
- ^ [6]


text:
Brief Description:
Find a queen in yourself with this pretty red dress. So make your date perfect with this sleeveless crew neck zipper sexy midi dress. Feel like princess with this amazing dress exclusively available on stylewe.com
Product details:
Daytime, evening, party wear
Pattern: Plain
97% cotton, 3% spandex
Process: Slit
Material: Polyester,Viscose
Pattern Type: Solid
Sleeve Length: Sleeveless
Style: Elegant
Occasion: Cocktail,Going out,Party
Neckline: Stand Collar
Silhouette: Sheath
Theme: Spring/Fall,Summer
Color: Red,Black
Size: XS,S,M,L
Composition: 92.5% Viscose, 7.5% Polyester
Bust (cm): XS:68, S:72, M:76, L:80
Waist (cm): XS:58, S:62, M:66, L:70
Hip (cm): XS:74, S:78, M:82, L:86
Length (cm): XS:101, S:102, M:103, L:104
App-exclusive Offer
20% off
1st OrderLEARN MORE


text:
Michaela – 6868
Released: June 23, 2016
Get your cock ready! Seems like it's its birthday. The present for you is this lovely MILF. A divorced mom of two always wanted to be a model. She will let you take a look at her fine ass, tuned-up tits and wet vagina. She will warm herself up with a vibrator and then polish your rod until it shines. This lady can do magic with cocks. She will get all the spunk out of your balls and expects you to cover her face in it.
Spare link: (try when other links are dead)


text:
Used in
Nicholas Nickleby
Go to Book Vocabulary
Kate, my dear,' said Mrs Nickleby; 'I don't know how it is, but a fine warm summer day like this, with the birds singing in every direction, always puts me in mind of roast pig, with
and onion sauce, and made gravy.
(not reviewed by editor)
These were proud times for Mrs Nickleby; never was anybody half so discreet and
as she, or half so mysterious withal; and never were there such cunning generalship, and such unfathomable designs, as she brought to bear upon Mr Frank, with the view of ascertaining whether her suspicions were well founded: and if so, of tantalising him into taking her into his confidence and throwing himself upon her merciful consideration.
(not reviewed by editor)
To see samples from other sources, click a sense of the word below:
as in: sage advice
as in: the growing sage
To see an overview of word senses, click
Go to Book Vocabulary
Learn more easily. Think more clearly. Express more effectively.


text:
by Staff Writers
Miami FL (SPX) Mar 09, 2017
University of Miami Rosenstiel School of Marine and Atmospheric Science scientist Mark Donelan and his Norwegian Meteorological Institute colleague captured new information about extreme waves, as one of the steepest ever recorded passed by the North Sea Ekofisk platforms in the early morning hours of Nov. 9 2007.
Within the first hour of the day, the Andrea wave passed by a four-point square array of ocean sensors designed by the researchers to measure the wavelength, direction, amplitude and frequency of waves at the ocean surface.
Using the information from the wave set--a total of 13,535 individual waves--collected by the system installed on a bridge between two offshore platforms, the researchers took the wave apart to examine how the components came together to produce such a steep wave.
The data from the 100-meter wide "wall of water" moving at 40 miles per hour showed that Andrea may have reached heights greater than the recorded height of 49 feet above mean sea level. They also found that rogue waves are not rare as previously thought and occur roughly twice daily at any given location in a storm. The findings showed that the steeper the waves are, the less frequent their occurrence, which is about every three weeks at any location for the steepest rogues.
The Andrea crest height was 1.63 times the significant height (average height of the one third highest waves). Optimal focusing of the Andrea wave showed that the crest could have been even higher and limited by breaking at 1.7 times the significant height. This establishes the greatest height rogues can reach for any given (or forecasted) significant height.
"Rogue waves are known to have caused loss of life as well as damage to ships and offshore structures," said Mark Donelan, professor emeritus of ocean sciences at the UM Rosenstiel School. "Our results, while representing the worst-case rogue wave forecast, are new knowledge important for the design and safe operations for ships and platforms at sea."
The study, titled "The Making of the Andrea Wave and other Rogues," was published in the March 8 issue of the journal Scientific Reports. The authors include: Donelan and Anne-Karin Magnusson from the Norwegian Meteorological Institute. The work was partly performed within the ExWaMar project (ID 256466/O80) funded by the Norwegian Research Council. ConocoPhillips provided the wave data.
Hong Kong (AFP) March 7, 2017
Hong Kong authorities have seized more than a tonne of shark fins as activists warn traders are sneaking the sought-after delicacy into the city by mislabelling shipments to get around bans by major transporters. The city is one of the world's biggest markets for shark fin - often served as a soup at expensive Chinese banquets - but it prohibits the trade in products taken from endangered ... read more
Related Links
University of Miami Rosenstiel School of Marine and Atmospheric Science
Water News - Science, Technology and Politics
|The content herein, unless otherwise known to be public domain, are Copyright 1995-2017 - Space Media Network. All websites are published in Australia and are solely subject to Australian law and governed by Fair Use principals for news reporting and research purposes. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA news reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. All articles labeled "by Staff Writers" include reports supplied to Space Media Network by industry news wires, PR agencies, corporate press officers and the like. Such articles are individually curated and edited by Space Media Network staff on the basis of the report's information value to our industry and professional readership. Advertising does not imply endorsement, agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. Privacy Statement


text:
Chris Squire
- Overview
- Biography
- Songs
- Browse by Format
- Browse by Genres
- Similar Artists
|Pop / Rock
|progressive rock bass symphonic prog art rock yes
|1970s 1990s 2000s
|allmusic BBC Music page discogs image IMDb last.fm other databases secondhandsongs VIAF wikidata wikipedia
4 March 1948, Wembley, London, England. An accomplished bass player who has made his name with supergroup Yes, having played with them for over 20 years. Yes was formed after Squire, then a member of the Syn, met Jon Anderson in a London music club. The original line-up consisted of Squire, Anderson, an extremely gifted vocalist and composer, guitarist Peter Banks, also a former member of the Syn, drummer Bill Bruford and organist Tony Kaye. Anderson, Banks and Squire had been in a band called Mabel Greers Toyshop in the last years of the 60s. Yes endured various personnel changes throughout the 70s, with Squire acting as a solid foundation for the band. By the mid-80s the line-up had been completely revamped by Squire with Andersons help. In 1977, Squire and another band member, Alan White (b. 14 June 1949, Pelton, Co. Durham, England; drums), appeared on Rick Wakemans solo, Criminal Record. Their music matured as the decade progressed, Squire...
- MatchChris Squire
- 100%Jon Anderson
- 84%Yes
- 63%Steve Howe
- 58%Steve Hackett
- 52%Bill Bruford
- 52%Bruford
- 51%Rick Wakeman
- 47%Patrick Moraz
- 47%Tony Banks


text:
Wavelets of lace lap at the trailing edge of this simple shawl textured with chevron furrows of garter ridge. The same instructions yield a large size with softly rustic fabric in Shelter or a smaller triangle with crisply defined motifs in Arbor.
Jewel tones make Terra perfect for autumn; a bright hue like Tincture will give you a shot of color to enliven an outfit in any season.
For Arbor, you'll need 5 skeins; for Shelter you'll also need 5 skeins.
Let's keep in touch!
Sign up for our newsletter & be first to hear about promotions, specials, and the latest new arrivals!