text:
BLAST+: architecture and applications
Sequence similarity searching is a very important bioinformatics task. While Basic Local Alignment Search Tool (BLAST) outperforms exact methods through its use of heuristics, the speed of the current BLAST software is suboptimal for very long queries or database sequences. There are also some shortcomings in the user-interface of the current command-line applications.
We describe features and improvements of rewritten BLAST software and introduce new command-line applications. Long query sequences are broken into chunks for processing, in some cases leading to dramatically shorter run times. For long database sequences, it is possible to retrieve only the relevant parts of the sequence, reducing CPU time and memory usage for searches of short queries against databases of contigs or chromosomes. The program can now retrieve masking information for database sequences from the BLAST databases. A new modular software library can now access subject sequence data from arbitrary data sources. We introduce several new features, including strategy files that allow a user to save and reuse their favorite set of options. The strategy files can be uploaded to and downloaded from the NCBI BLAST web site.
The new BLAST command-line applications, compared to the current BLAST tools, demonstrate substantial speed improvements for long queries as well as chromosome length database sequences. We have also improved the user interface of the command-line applications.
Basic Local Alignment Search Tool (BLAST)
BLAST is one of the more popular bioinformatics tools. Researchers use command-line applications to perform searches locally, often searching custom databases and performing searches in bulk, possibly distributing the searches on their own computer cluster. The current BLAST command-line applications (i.e., blastall and blastpgp) were available to the public in late 1997. They are part of the NCBI C toolkit
The initial BLAST applications from 1997 lacked many features that are presently taken for granted. Within three years of the initial public release, BLAST was modified to handle databases with more than 2 billion letters, to limit a search by a list of GenInfo Identifiers (GIs), and to simultaneously search multiple databases. PHI-BLAST
Many mammalian genomes contain a large fraction of interspersed repeats, with 38.5% of the mouse genome and 46% of the human genome reported as interspersed repeats
NCBI recently redesigned the BLAST web site
The advent of complete genomes resulted in much longer query and subject sequences, leading to new challenges that the current framework cannot handle. At the same time, increases in generally available computer memory made other approaches to similarity searching viable. BLAT
In this article, a search type is described by a word or two in all upper-case letters. For example, a BLASTX search translates the nucleotide query in six frames and compares it to a protein database.
This section reports first on the overall design of the new software and then discusses several enhancements to BLAST.
Overall design
Two criteria were most important in the design of the new BLAST code: 1.) the code structure should be modular enough to allow easy modification; and 2.) the same BLAST code should be embedded in at least two different host toolkits. This would allow both the new NCBI C++ toolkit and the older NCBI C toolkit to use the same BLAST source code.
At a high level, the BLAST process can be broken down into three modules (Figure
Figure 1
Schematic of a BLAST search
Schematic of a BLAST search. The first phase is "setup". The query is read, low-complexity or other filtering might be applied to the query, and a "lookup" table is built. The next phase is "scanning". Each subject sequence is scanned for words ("hits") matching those in the lookup table. These hits are further processed, extended by gap-free and gapped alignments, and scored. Significant "preliminary" matches are saved for further processing. The final phase in the BLAST algorithm, called the "trace-back", finds the locations of insertions and deletions for alignments saved in the scanning phase.
The setup phase reads the query sequence, applies low-complexity or other filtering to it, and builds a "lookup" table (i.e., perfect hashing). The lookup table contains only words from the query for nucleotide-nucleotide searches such as BLASTN or MEGABLAST. DISCONTIGUOUS MEGABLAST allows non-consecutive matches in the initial seed. Protein-protein searches such as BLASTP allow "neighboring" words. The neighboring words are similar to a word in the query, as judged by the scoring matrix and a threshold value.
The scanning phase scans the database and performs extensions. Each subject sequence is scanned for words ("hits") matching those in the lookup table. These hits are used to initiate a gap-free alignment. Gap-free alignments that exceed a threshold score then initiate a gapped alignment, and those gapped alignments that exceed another threshold score are saved as "preliminary" matches for further processing. The scanning phase employs a few optimizations. The gapped alignment returns only the score and extent of the alignment. The number and position of insertions, deletions and matching letters are not stored (no "trace-back), reducing the CPU time and memory demands. Searches against nucleotide subject sequences consider only unambiguous bases (A, C, G, T), with ambiguous bases (e.g., N) replaced at random during preparation of the BLAST database or subject sequence. A four letter alphabet allows packing of four bases into one byte, and the subject sequences are scanned four letters at a time. Finally, less sensitive heuristic parameters are employed for the gapped alignment, and the full extent of a gapped alignment may, in rare cases, not be found.
The final phase of the BLAST search is the trace-back. Insertions and deletions are calculated for the alignments found in the scanning phase. Ambiguous bases are restored for nucleotide subject sequences, and more sensitive heuristic parameters are used for the gapped alignment. Composition-based statistics
Ideally, one should be able to independently replace the functionality described in each of the small rectangles of Figure
The selection of ISO C99 allows use of the new BLAST code in both C and C++ environments. The host toolkit provides a software layer to allow BLAST to communicate with the rest of each toolkit. This design requires a clean separation between the algorithmic part of BLAST and the module that retrieves subject sequences from the database. To allow this, the retrieval of subject sequences for processing by the core of the BLAST code is performed through an Abstract Data Type (ADT), which specifies a set of data values and permitted operations. The actual retrieval occurs through an implementation of the ADT in the host toolkit. The implementation can be changed depending upon the need and requires no changes to the BLAST algorithm code itself.
The subject sequence information required by BLAST is quite simple. It consists of the total number of sequences to be searched, the length of any given sequence, as well as methods to retrieve the actual sequence. The total database length is needed for calculation of expect values. A database name and the length of the longest subject sequence are also required to implement some functions in an efficient manner. In order to satisfy the above requirements, an ADT, called the BlastSeqSrc
Database masking
Low-complexity regions and interspersed repeats typically match many sequences. These matches are normally not of biological interest, may lead to spurious results, and confound the statistics used by BLAST. BLAST offers two query masking modes to avoid such matches. One is known as "hard-masking" and replaces the masked portion of the query by X's or N's for all phases of the search. On the other hand, "soft-masking" makes the masked portion of the query unavailable for finding the initial word hits, but the masked portion is available for the gap-free and gapped extensions once an initial word hit has been found.
The BLAST databases can also be masked. Masking information is stored as a series of intervals, so that masking can be switched on or off. Information from multiple masking algorithms can be stored in the same BLAST database and accessed separately. Currently, database masking consists of skipping masked portions of the database during the scanning phase, but it is still possible to extend through masked portions of the database; as such, database masking is analogous to soft-masking a query.
Minimizing memory and cache footprint
Modifications that reduce the CPU time and memory footprint of BLAST searches with long query or subject sequences are examined. First, an optimization for the scanning phase of the BLAST search is presented. Then, an improvement for the trace-back phase is described.
BLAST searches with very large queries are routine, but some of the data structures scale with the query length. The following analysis examines the scanning phase (Figure
Two large structures are frequently accessed during the scanning phase. The first is the "lookup table", which maps words in a subject sequence to positions in the query. The second is the "diag-array", which tracks how far BLAST has already extended word hits on any given diagonal; its size scales with the query length. The scanning phase is a large fraction of the time of most BLAST searches, so these structures must be accessed quickly. Contemporary CPUs typically communicate with main memory through several levels of cache, called a "memory hierarchy". For example, the L1 cache is the smallest and has the lowest latency; the L2 cache is larger but slower. On a machine with an Intel Xeon CPU, the L1 cache might be around 16 kB and the L2 cache can range in size from 0.5-4 MB. If the CPU does not find data or an instruction in the cache, it must fetch it from main memory; a "cache miss". Performance could be improved by making the lookup table and diag-array small enough to fit into L2 cache, still leaving room for instructions and other data.
In order to be specific, the discussion in the next two paragraphs is limited to a BLASTX search, which translates a nucleotide query in six frames (three frames on each strand) and compares it to a protein database.
The lookup table contains a long array (the "backbone"), with each cell mapping to a unique word. The lookup table translates each residue type to a number between 1 and 24, so a three-letter word maps to an integer between 1 and 243. For a three-letter word, an array of 32768 (323) cells allows a quick calculation of the offset into the backbone while scanning the database for word matches. Each cell of the backbone consists of four integers. The first integer specifies how many times that word appears in the query; the other three can have one of two functions. For three or fewer occurrences, the three integers simply specify the positions of the word in the query. If there are more than three occurrences, however, the integers are an index into another array containing the positions of the word in the query. The total memory occupied by the backbone is 16 bytes × 32768, or about 524 kB. Finally, there is a bit vector occupying 4096 bytes (32768/8). The corresponding bit is set in the bit vector for backbone cells containing entries. For a short query, where the backbone may be sparsely populated, this allows a quick check whether a cell contains any information.
A BLASTX query of N nucleotides becomes twice as long when it is represented as six protein sequences. The diag-array consumes one four-byte integer per letter in the query. An estimate of the total memory occupied by the lookup table backbone and the diag-array, in bytes, for a nucleotide query of length N is:
For a query of N = 50 k, this is close to a million bytes, already the total size of L2 cache in many computers used for BLAST searching. Modifications to these structures might permit larger queries, but for contigs and chromosomes the structures would still overflow the L2 cache. To overcome this, the query is split into smaller overlapping pieces for the scanning phase of the search. BLAST then merges the results and aligns the entire query during the trace-back phase, obtaining the same results as a search that was not split. Splitting the query has an additional advantage; since the sub-query used during the scanning phase is of bounded length, it is possible to use a smaller data type in the lookup table (specifically, a two byte rather than a four byte integer). This reduces the first term in the above equation from 528,384 to 266,240 bytes.
The final phase of the BLAST search, the trace-back, processes the preliminary matches, producing an alignment with insertions and deletions. Additionally, heuristic parameters may be assigned a more sensitive value, ambiguities in a nucleotide database sequence are resolved, and the composition of the subject sequences may be taken into account when calculating expect values. Some subject sequences must be retrieved again for this calculation, but since the preliminary phase finds the rough extent of any alignment, the entire sequence is often not needed. This is most important for short queries searched against a database of much longer sequences. Only part of the subject sequences, when appropriate, is now retrieved, and performance results are presented under "Partial subject sequence retrieval" below.
Results and discussion
First, we introduce a set of BLAST command-line applications built with the software library discussed above. Then, we present an example use of database masking as well as two performance analyses that demonstrate improvements in search time: searches with very long queries and searches of chromosome-sized database sequences. For each performance analysis, we prepared a baseline application that disables the new feature being tested. Finally, we discuss an example of retrieving subject sequences from an arbitrary source.
A SUSE Linux machine with an Intel Xeon 3.6 GHz CPU, 16 kB of L1 cache, 1 MB of L2 cache, and 8 GB of RAM, provided data for the comparisons described here.
BLAST+ command-line applications
New command-line applications have been developed using the NCBI C++ toolkit, and they are referred to as the BLAST+ command-line applications (or BLAST+ applications). Extensive documentation about the different command-line options is available
Power users of BLAST often have a specially crafted set of command-line options that they find useful for their particular task. However, lacking a method to save these, they must write scripts or simply re-type them for each search. The BLAST+ applications can write the query, database, and command-line options for a BLAST search into a "strategy" file. A user may then rerun a set of commands by specifying the strategy file, though a new query and database can be specified with the command-line. This file is currently written as ASN.1 (Abstract Syntax Notation, a structured language similar to XML), but an XML option could be added in the future. Users can also upload this file to the NCBI BLAST web site to populate a BLAST search form, or download a strategy file for a search performed at the NCBI BLAST web site.
The BLAST+ applications have a number of new features. A GI or accession may be used as the query, with the actual sequence automatically retrieved from a BLAST database (the sequence must be available in a BLAST database) or from GenBank. The applications can send a search to NCBI servers as well as locally search a set of queries against a set of FASTA subject sequences
Tables listing the command-line options, as well as their types and defaults, were provided as additional file
Additional file 1
Eight tables list the command-line application options, as well as their types, default values, and a short explanation. The first table has information common to the search applications blastn, blastp, blastx, tblastn, and tblastx. The next five tables describe options for those applications. The last two tables list the options for makeblastdb (used to build a blast database) and blastdbcmd (used to read a database).
Click here for file
Database masking
Applying masking information to the BLAST database rather than the query will improve the workflow for BLAST users. A specialized tool, such as WindowMasker
To test the performance of database masking, 163 human ESTs from UniGene cluster 235935 were searched against the build 36.1 reference assembly of the human genome
Table 1
Comparison of query versus database masking.
Type of masking
Number of alignments found
GIs of extra sequences found
13529935, 14400848, 14430244, 14430457
Currently, database masking is not supported for searches of translated database sequences (i.e., tblastn and tblastx), but it will be supported in the near future.
Database masking is not a new concept. Kent
Query splitting
Breaking longer queries into smaller pieces for processing can lead to significantly shorter search times. At the same time, splitting the query into pieces makes it possible to guarantee that the query length is always bounded, allowing the use of smaller data types in the lookup table. Use of smaller data types with a BLASTP search (protein-protein) shows no improvement for sequences under 500 residues, but performance increases by up to 2% as the sequence length increases to 8000 residues. Use of a smaller data type never makes performance worse, so it is used in the tests described in this section.
BLAST searches of differently-sized chunks of zebra fish chromosome 2 [Genbank:
Figure 2
Speedup of BLASTX searches for differently sized queries with and without query splitting
Speedup of BLASTX searches for differently sized queries with and without query splitting. Different sized pieces of [Genbank:
Figure 3
L2 data cache misses for BLASTX searches with and without query splitting
L2 data cache misses for BLASTX searches with and without query splitting. Cache misses were measured by Cachegrind
Cameron et al.
Partial subject sequence retrieval
Partial retrieval of subject sequences is most effective when a small fraction of the subject sequence is required in the trace-back phase, such as in a search of ESTs against chromosomes. A baseline blastn application that retrieves the entire subject sequence in the trace-back phase was prepared. 163 human ESTs from UniGene cluster 235935 were searched against the masked human genome database from build 36.1 of the reference assembly
Figure 4
Scatter plot of MEGABLAST search times with and without partial retrieval
Scatter plot of MEGABLAST search times with and without partial retrieval. 163 human ESTs from UniGene cluster 235935 were searched against all human chromosomes
Retrieving subject sequences from an arbitrary source
An Abstract Data Type (ADT) supplies the subject sequences to be searched in the new BLAST code. This abstraction avoids coupling the BLAST engine to a particular database format. It permits a search of sequences in the "Short Read Archive" (SRA) at the NCBI through the SRA Software Development Kit
Future development
Future developments include adding hard-masking support for databases, and making database masking available for programs with translated database sequences (tblastn and tblastx). At this point, only the scanning phase of the BLAST search is multi-threaded; we also plan to make the trace-back phase multi-threaded.
We have reported on a new modular software library for BLAST. The design allows the addition of features that greatly benefit performance, such as query splitting and partial retrieval of subject sequences. It also allows the replacement of the lookup table with another design, so that new implementations can easily be added. An indexed version of MEGABLAST
We also described a new set of BLAST command-line applications. The applications have a new, more logical organization that groups together similar types of searches in one application. The concept of a task allows a user to specify an optimal parameter set for a given task. Strategy files were also introduced, allowing a user to record parameters of a search in order to later rerun it in stand-alone mode or at the NCBI web site.
Availability and requirements
BLAST is Public Domain software
Authors' contributions
All authors participated in the design and coding of the software. TLM drafted the manuscript and the other authors provided feedback. All authors read and approved the final version of the manuscript.
A number of people contributed to this project. Richa Agarwala, Alejandro Schaffer, and Mike DiCuccio offered ideas and feedback. Mike Gertz, Aleksandr Morgulis, and Ilya Dondoshansky contributed some of the code used in the core of BLAST. Denis Vakatov, Aaron Ucko and other members of the NCBI C++ toolkit group offered assistance as well as the C++ toolkit used to build BLAST+. Eugene Yaschenko, Kurt Rodarmer and Ty Roach provided help in using the NCBI SRA Software Development Toolkit. David Lipman and Jim Ostell originally suggested the need for a rewritten version of BLAST and provided encouragement and feedback. Greg Boratyn, Maureen Madden and John Spouge read the manuscript and offered helpful suggestions.
This research was supported by the Intramural Research Program of the NIH, National Library of Medicine. Funding to pay the Open Access publication charges for this article was provided by the National Institutes of Health.
Basic local alignment search tool
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
NCBI C toolkit
Protein sequence similarity searches using patterns as seeds
IMPALA: matching a protein sequence against a collection of PSI-BLAST-constructed position-specific score matrices
Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements
A greedy algorithm for aligning DNA sequences
Initial sequencing and comparative analysis of the mouse genome
RepeatMasker Web site
NCBI BLAST web site
NCBI BLAST: a better web interface
BLAT--the BLAST-like alignment tool
A deterministic finite automaton for faster protein hit detection in BLAST
NCBI C++ toolkit documentation
Implementing a BlastSeqSrc
BLAST+ Command Line Applications User Manual
Improved sensitivity of nucleic acid database searches using application-specific scoring matrices
WindowMasker: window-based masker for sequenced genomes
Analysis of compositionally biased regions in sequence databases
A fast and symmetric DUST implementation to mask low-complexity DNA sequences
Reference assembly for Human genome build 36.1
Database indexing for production MegaBLAST searches
NCBI SRA Software Development Kit
PUBLIC DOMAIN NOTICE for NCBI


text:
Renaming Files
You may rename or move files, folders, and symbolic links to a new pathname, provided that you have sufficient permissions.
Select the object you wish to rename in one of the file browsers, then click the Rename button beneath that browser. You will be presented with a dialog box containing the current pathname of the file. Change this to the new pathname and click "Okay".
Renaming a symbolic link will change the name or path of the link itself, but will not change the target path. As always, moving a symbolic link which has a relative target path may break the link.
Confirmations or errors will be displayed in the message box at the bottom of the window.

subset: commoncrawl


text:
The Dairy
At The Dairy, we only allow the best! Our phone cases are made with lots of love, high quality materials, the best technique and some chocolate cake, ice cream with a good helping of fruit and whipped cream on top. We love you that much and we hope it shows!


text:
Minimum of 9 hours conference and independent work; 3 credits
Independent or group project approved by a faculty committee. The project must involve more than one department in the college. Achievement evaluated by the participating faculty. Students may repeat the course once, but may not repeat topics.
Prerequisite: junior or senior standing; and Women's Studies 1001 [12]; and three electives from those listed under program requirements; and permission of the program coordinator and at least one sponsoring faculty member.
Take advantage of our two five-week summer sessions for both undergraduate and graduate students.
We'll show you around and introduce you to one of the most beautiful campuses in the country. Arrange a tour today.
Our faculty not only share their discoveries and knowledge with you, they invite you to be active members of their research teams.
A privately owned residence hall is located just blocks from the college.
© 2017 All Rights Reserved Brooklyn College
2900 Bedford Avenue, Brooklyn, NY 11210


text:
Avandia Should Stay on Market, But Restrict Sales, FDA Advisory Panel SaysJul 15, 2010 | Parker Waichman LLP
While Avandia poses "significant safety concerns," a sharply divided Food & Drug Administration (FDA) panel voted that the controversial diabetes drug should be allowed to stay on the market. However, the panel of outside experts also said sales of Avandia should be restricted.
The votes came at the end of a two-day meeting where GlaxoSmithKline, Avandia's maker faced tough criticism for the way it handled the drug and its cardiovascular risks.
According to The New York Times, 12 of the panel's 33 members voted that Avandia should be withdrawn; 10 voted that its sales should be restricted and the warnings on its label enhanced; 7 voted only to support enhanced warnings on the drug's label; and 3 voted that the drug should continue to be sold with its present warnings unchanged.
The FDA is not required to follow the recommendations of such panels, but does so in most cases. However, the lack of unity among panel members in the case of Avandia makes it hard to predict what the agency will do, The Times said.
Avandia was the biggest selling diabetes drug in the world, until 2007 when a Cleveland Clinic study raised questions about its heart risks. The study, conducted by Dr. Stephen Nissan, showed patients taking Avandia had a 43-percent higher risk of having a heart attack. The drug's label has borne a black box warning – the FDA's most serious safety alert – regarding its heart attack risk since November of that year.
Last month, Nissan released a follow-up to that study, which found an increased heart attack risk of 28 percent. The update was among the evidence presented to the FDA advisory panel.
Also considered by the panel was a study conducted by Dr. David Graham, an FDA researcher. That study, which involved 227,500 Medicare patients, found that those who took Avandia were 27 percent more likely to suffer a stroke, 25 percent more likely to develop heart failure and 14 percent more likely to die compared with those who took another drug called Actos.
An Avandia study called RECORD, which was funded by Glaxo and used to tout the drug's safety, was sharply criticized during the two-day meeting, with Graham telling the panel: "You can't trust it, and if we do trust it, we're engaging in the willing suspension of disbelief." He also characterized RECORD as "garbage".
Last week, a memo in a 756-page briefing document posted to the FDA Web site characterized RECORD as "inadequately designed and conducted to provide any reassurance about the CV (cardiovascular safety) of rosiglitazone." The memo further states that the RECORD results "confirm and extend the recognized concerns regarding heart failure" and possibly suggest an increased risk for heart attacks.
According to an earlier New York Times report, the FDA review of RECORD found at least a dozen instances in which patients taking Avandia suffered serious heart problems that were not counted in the trial's tally of adverse events, mistakes that further obscured Avandia's heart risks.


text:
When I watched reruns in the late 70s when my hormones were raging I always wanted to bend Judy over the piano, if you know what I mean. When she was in her spacesuit she was smoking hot.
I always wondered why Major West didnt do her? I mean was he gay? Was there a single time when Don kissed a woman or even showed interest? Was he a eunuch? Don seemed to be John Robinson toadie - similar to Robins role in Batman. I suppose maybe John Robinson told Don he would tear him in half if he deflowered Judy.
And what about poor Wil and Penny? Those two in the throes of full blown puberty with nothing but each other? Ok, thats downright creepy. Id better stop here.
And dont even get me started about Dr Smith who was always making eyes at Wil Robinson. I suspect that when Robot was waving his claws around wailing "Danger Wil Robinson!" he was talking about Dr. Smith. Whatever the case Dr. Smith was even gayer than Major West. In fact if the series was filmed today Im sure Smith and West would be in a domestic partnership seeking to adopt Wil. Dr. Smith is widely regarded as the first Gay character in space.
All in all its a childhood memory and its better left there.


text:
- Trending Now: More Trending:
- beleaguer scaramouch non sequitur admiral's mast calumny
break open
Definition of break open
: to open or to cause (something) to open suddenly The pods broke open and the seeds scattered on the wind. The police broke open the door. The burglars broke the locked safe open.
Word by Word Definitions
: to separate into parts with suddenness or violence
: fracture
: to fracture a bone of (a bodily part)
: having no enclosing or confining barrier : accessible on all or nearly all sides
: being in a position or adjustment to permit passage : not shut or locked
: having a barrier (such as a door) so adjusted as to allow passage
: to move (something, such as a door) from a closed position
: to make available for entry or passage by turning back (something, such as a barrier) or removing (something, such as a cover or an obstruction)
: to make available for or active in a regular function
: opening
: open and unobstructed space: such as
: open air
Seen and Heard
What made you want to look up break open? Please tell us where you read or heard it (including the quote, if possible).


text:
CLICK SUBSCRIBE!! FIND ME ON SOCIAL MEDIA!! Facebook: https://www.facebook.com/pages/NISHMUSICHOUSE Twitter: ...
MIKE PINERA~Must Get Thru [1978] MP3
An awesome tune from the ISLA album released in 1978 on the Capricorn label. The complete album can be found at ...
It Must Be An Officer's Daughter-Can't Get Through-Hairy Chapter(1970) MP3
German prog/hard rock band.
Must Get Thru MP3
Provided to YouTube by The Orchard Enterprises Must Get Thru · Mike Pinera Isla ℗ 2011 Cleopatra Records Released on: 2011-07-01 Auto-generated by ...
I Must Get Thru MP3
Provided to YouTube by Believe SAS I Must Get Thru · Cosmic Rockout Hopney ℗ Dodo Released on: 2014-06-22 Author: Hopney Author: Pinera Composer: ...
I Must Get Through MP3
Provided to YouTube by CDBaby I Must Get Through · Millsbee Like June ℗ 2011 Matthew Lawson Released on: 2011-01-27 Auto-generated by YouTube.
Must Get Thru MP3
Provided to YouTube by The Orchard Enterprises Must Get Thru · Mike Pinera Anthology Box 1975-1979 ℗ 2011 Cleopatra Records Released on: 2011-09-13 ...
#Apostle Johnson Suleman(Prof) #He Must Go Through Samaria #1of2 #Ibadan Invasion 2015 MP3
He Must Go Through Samaria #1of2 Ibadan Invasion 2015 Apostle Johnson Suleman Senior Pastor Omega Fire Ministries Worldwide +2348084227205 ...
The Jimi Hendrix Experience - All Along The Watchtower (Official Audio) MP3
Click to subscribe: http://smarturl.it/SubscribeJHVevo?IQid=ytd.jh.AATWA Taken from the album 'Experience Hendrix': http://smarturl.it/ExperienceHendrix?
All Along The Watchtower
The Jimi Hendrix Experience"There must be some kind of way out of here," said a joker to the thief "There's too much confusion, I can't get no relief B[...]
I gotta get thru this .....dance must watch MP3
Dancing everywhere .tryna dance for a music video my dream.
Anxiety Sufferers #1 Must Watch You Can Get Through This Video#1 MP3
VIDEO#2 http://youtu.be/hfB6oMfdz_w VIDEO#3 http://youtu.be/Bd8oobElfZ4 being an anxiety suffer and knowing the internal pain and misery of this physical ...
The Trucks must get through with the Earthquake Relief Aid. MP3
On route to the Earthquake Zone of La Libertad, Negros Oriental, Philippines we encountered a scary situation caused by a fresh landslide, with an inch to spare ...
Ascension Healing Tools | Cardinal Cross Grand Cross | How to get through this time. (MUST WATCH) MP3
Hi everyone, this video is created to help help guide us through this powerful energy shift. First Video I speak about ...
The Mail Must Get Through (FFXIV) MP3
Cid makes his first appearance near the end.
Great Dane Lucy gets through cat door! A must see! MP3
We've been finding our great dane Lucy in the basement lately, and I finally got a video of how our Houdini did it! Lol.
Final Fantasy XIV Twin Adder 02 The Mail must get through 1080p MP3
Final Fantasy XIV- The Mail Must Get Through (Part 1/2) MP3
Part 1.
Skylanders trap team how to get through unknown gate (must have hood sickle trapped) MP3
Hope this helped! And remember to like,comment and subscribe!
'We Must Dig In And Get Through To Tea' - Clarke's Teary Tribute MP3
Among the touching eulogies to Phil Hughes on Wednesday during his funeral service at the Macksville High School was his close friend, New South Wales and ...
MUST SEE!!! | Raw Footage!!! Vehicle Crashes Through Gates Almost Getting Killed By CN Train MP3
Please watch in 1080p for best quality. *Warning, the F word was used during this video. What you are watching is raw footage, and yes he smashed through the ...
#Apostle Johnson Suleman(Prof) #He Must Go Through Samaria #2of2 #Ibadan Invasion 2015 MP3
He Must Go Through Samaria #2of2 Ibadan Invasion 2015 Apostle Johnson Suleman Senior Pastor Omega Fire Ministries Worldwide +2348084227205 ...
Arma 3 - Hetman: War Stories Episode 2 - They Must Not Get Through MP3
The battle continues from the viewpoint of two participants as we struggle to stop the enemy breaching our lines. Someone once asked for bayonets in Arma 3.
Anxiety Sufferers #2 Must Watch You Can Get Through This Video#2 MP3
Video #1 http://youtu.be/_M0-OKsoCdc Video #3 http://youtu.be/Bd8oobElfZ4 being an anxiety suffer and knowing the internal pain and misery of this physical ...
Must Get Free - Line Dance ( Dance & Walk Through) MP3
More videos on http://suenkathy.com/stepsheet_table.aspx Must Get Free Choreographed by: Dan McInerney, UK (Sept 09) Music: Silk by Rachel Stevens (CD: ...
Taxi Nearly Takes Me Out Through Pinch Point 14-07-2015 MP3
In this instance the must get in front attitude creates a fairly close pass through a pinch point despite my hand signalling.
20 PS4 Games You Must Play In 2015 MP3
2015 is looking like a massive year for PlayStation 4! We take you through the 20 PS4 games you need to start getting excited about over the coming year.
Sermon: You Must Go Through Hell to Get to Heaven MP3
http://fergusonhtscoc.org You Must Go Through Hell to Get to Heaven by Conley Gibbs, Jr. On October 27, 2013.
Must see how deaf Man cured by mula Ali through reading some verses from holy Quran MP3
this man can't speak for some days, may be he get accident or some bad temper, then he get cured and returned back to previos situation after reciting some ...
Daniel Bedingfield- Gotta Get Thru This (uk version) MP3
FOR THOSE WHO ARE WANTING TO SIGN THE BIRTHDAY Guest Book~~~~~~~~~ Here is the Link: ...


text:
Shattered into a Million bits!
Dear Governor Schnitzel,
Would you like to never walk again? I think absolutely not! I strongly believe that you and All the kings horses and all the kings men must compensate me for my horrible fall. The men gave up after 15 minutes with mouth to mouth without even taking me to a hospital! How negligent! I paid thousands to the plastic surgery clinic to fix my body and I'm still in a million bits. But most importantly,I can't exercise...the one important thing the egg body needs. I order you and the kings men to compensate me for the accident...or I'll be having to the wicked witch!
To begin with, they gave up after 15 minutes. 15 minutes with the kings men doing stupid things like mouth to mouth, CPR & gluing my shell together.Get this, instead of wasting 15 precious minutes on irrelevant things, put me in the horse carriage and get me to a hospital! They shouldn't put a eggs life in danger! They get it together and do there stupid job!
Secondly, I paid a lot of money for plastic surgery. The kings men pay for it? No they just did nothing. How rude! They gave up after 15 minutes, so they should pay the money. I was in excruciating pain and I paid almost one million dollars to plastic surgery for nothing. Not only that but I missed my race in the 1988 Olympics! I have trained all my egg life for the 1988 Olympics,but because of those cruel men, I missed my one and only race. I have been sad all my life because of you and your men!
Finally, I can't even exercise! This is highly important, because eggs needs exercise to make the youk tasty. Oh right, I don't have a youk. Because of this I have put on a lot of weight. Not only am I still in a million bits, but I am very overweight! Just think, I could be running in the green grass, feeling the wind through my shell...but instead I am a fat egg in a million bits sitting on my couch. This all because you and your men in 1686.
In conclusion, you have to pay for me. I have been sad for around 460 years now and you still haven't paid! Everyone thinks the kings men tried, but they don't what happened behind the scenes. They think you and the men are nice, but you and your men are evil. But anyway...as I said, If you don't pay I will be talking to the wicked witch or the giant! It's your choice.
Humpty Dumpty


text:
Take Her EasyFavorites [+]
Pay-Per-Minute Viewing
You can now enjoy this movie on your iPhone®, iPad®, or compatible Smart TV & Android devices.
Purchase Options
Pay-Per-MinutePurchase Minutes
Streaming Rentals
Available MP4 sizes:SD 480p (2.06 GB)
DRM-free downloads offer content that is not limited by standard Digital Rights Management (DRM) access technologies. These technologies allow hardware manufacturers, publishers, copyright holders and individuals to limit the usage of digital content.
When you purchase DRM-free downloadable content, that content is available for you to download on any computer and save to a disk whenever you like. You can also download to multiple computers. There is no timeframe associated with your purchase and the content will not expire.
Running Time: 136 minutes
Released: 04/2010
Studio Name: SunLust Pictures
Description: Packed to the brim with 7 big scenes including Taylor Vixen's smoking hot G/G encounter. Who gives a fuck? They do! They fuck and suck and cum all over.
6 Scenes from Take Her Easy
Take Her Easy: Scene 1 Free Preview
Starring: Evan Stone Phoenix Marie ... More Details
Stars: Evan Stone, Phoenix Marie
Sex Acts: Handjob, Deep Throating, Oral Sex, Rim Job, Wet / Messy, Vaginal Sex, Choking
Positions: Sitting, Standing Doggy Style, Crouching/Squatting, Standing Missionary, Side Saddle, Spoons position, Missionary, Laying, Cowgirl, Kneeling
Take Her Easy: Scene 2 Free Preview
Starring: Alec Knight Victoria Sweet ... More Details
Stars: Alec Knight, Victoria Sweet
Sex Acts: Breast Play, Handjob, Deep Throating, Oral Sex, Rim Job, Masturbation, Vaginal Sex
Positions: Standing, Sitting, Standing Doggy Style, Standing Missionary, Reverse Cowgirl, Cowgirl
Settings: Office
Take Her Easy: Scene 3 Free Preview
Starring: Charmane Star Gianna Lynn ... More Details
Stars: Charmane Star, Gianna Lynn, Zoe Britton
Sex Acts: Girl on Girl action, 3-Way, Breast Play, Masturbation, Oral Sex
Take Her Easy: Scene 4 Free Preview
Starring: Tommy Gunn Crissy Moon ... More Details
Stars: Tommy Gunn, Crissy Moon
Sex Acts: Breast Play, Handjob, Masturbation, Footplay, Vaginal Sex, Deep Throating, Oral Sex
Positions: Standing Doggy Style, Side Saddle, Spoons position, Missionary, Laying, Reverse Cowgirl, Cowgirl, Kneeling, Doggy Style
Take Her Easy: Scene 5 Free Preview
Starring: Marcus London Mason Moore ... More Details
Stars: Marcus London, Mason Moore
Sex Acts: Breast Play, Stripping, Handjob, Masturbation, Vaginal Sex, Choking, Deep Throating, Oral Sex, Squirting
Positions: Standing, Standing Missionary, Sitting, Missionary, Laying, Reverse Cowgirl
Settings: Photo Studio
Take Her Easy: Scene 6 Free Preview
Starring: Nikki Rhodes Taylor Vixen ... More Details
Stars: Nikki Rhodes, Taylor Vixen
Sex Acts: Breast Play, Girl on Girl action, Masturbation, Oral Sex, Vaginal Sex
Settings: Bedroom
Recommended Movies
AEBN Cams


text:
Listing information
- Beds: 3
- Total Rooms: 12
- New Construction: No
- Lot Area: 3.71
- County: Medina
- Style: Colonial
- Baths: 2 (Full: 2 3/4: 0 1/2: 0 Other: 0)
- Stories: 1
- Foreclosure: No
- Lot Size: 422x380
- School District: Black River Lsd
- Year Built: 1913
- Status: Sold on 9/22/2016
- Parking Type Description: Detached 2 cars
- Total Square Footage: 1,982 ($85.72 per sq. foot)
- Estimated Annual Taxes: $1,600
Appliances Equipment Dishwasher, Dryer, Freezer, Humidifier, Microwave, Range, Refrigerator, Security System, Smoke Detector, Sump Pump, Washer
Available Financing Cash, Conventional, FHA/VA
Basement Detail Full, Unfinished, Walk-Out
Basement Y/N Yes
Cooling Type Central Air
Disability Features Y/N No
Driveway Paved, Unpaved
Dwelling Type Detached
Elevator Y/N No
Exterior Aluminum
Exterior Features Barn/Stable, Deck, Porch, Storage Shed/Out Bld
Fences Other
Financing FHA
Fixer Upper No
Garage Features Detached, Door Opener, Drain, Electric, Heated
Heating Fuel Pellets
Heating Type Geothermal, Wood/Pellet Heat Sys
HOA Y/N No
House Faces North
Irregular Lot Y/N No
Maint Fee Y/N No
Other Full Baths Lower - 0, Full Baths Main - 2, Full Baths Upper - 0
Possession Time of Transfer
Property Subtype Single Family
Pub Transportation Y/N Yes
Roof Asphalt/Fiberglass
Warranty Y/N No
Water Sewer Public Water, Septic
Bedroom Second
Other Second
Additl. Living Suite First
Bedroom First
Family Room First
Kitchen with Eating Space - Eat-in Kitchen First
Laundry Room First
Living Room First
Master Bedroom First
Office First
Other First
Other First
Listing Courtesy of Russell Real Estate Services


text:
Disclosure : We are a website that needs compensation to operate like any other website on internet. We may receive consideration for our reviews but are totally unbiased and do not accept paid reviews or fake reviews claiming to be something they are not.
EUKHOST ( Lst updated on 08/04/2016 )
Current Promotion Offers From EUKHOST :
All VPS Services - 20% OFF - Coupon Code - VPS2015 - Couponlink
Click and use the coupon codes : AFFCloud20
Cloud Servers - 20% OFF - Coupon code -
Check out Coupon Banners also.
50% OFF - Linux VPS Servers for first two months
Smarter Bundle Professional Edition - FREE with all Windows VPS plans, Hyper-Cloud and Windows Dedicated Servers
Founded in : 2001
Situated at : Leads, UK
Datacenters : Located at : Maidenhead and Milton Keynes, has 1200 servers
Number of Domains hosted : Over 150,000 with 35,000+ customers.
Contacts and Support Offered :
Physical address : Provided
Email addresses : NA instead contact forms are provided
Phone numbers : Provided
Fax numbers : Provided.
Skype number : Provided
Products and Services Offered by eUKHOST:
Shared Hosting :
cPanel Hosting - From GBP 2.75/mo
Build a Website - GBP 3.49/mo
Domain Web hosting - From GBP 2.75/mo
Windows Hosting - From GBP 4.42/mo
Business Hosting - From GBP 19.99/mo
Reseller Hosting :
cPanel WHM Reseller Hosting - From GBP 14.99/mo
Windows Reseller Hosting - From GBP 14.99/mo
Linux VPS Hosting : From GBP 22/mo
Windows VPS Hosting : From GBP 29/mo
Cloud Hosting :
CloudCopy Cloud Storage - 100% Secure
eNight Cloud Hosting - Up to 60% saving
Private Cloud Hosting
Dedicated Servers :
Managed Dedicated Servers
Server Mirroring
Linux Load Balanced Servers
Network Load Balanced Servers
Backup Solutions
Compiled by : Sudhir Jain
Friday, March 22, 2013
Posted by SUDHIR at 8:28 PM
1 comment:
Subscribe to: Post Comments (Atom)


text:
Must Visit
Mahakaleshwar Temple is regarded as one of the most auspicious temples of the Hindus in the sacred town of Ujjain. The temple lies near a lake. The temple has a broad courtyard surrounded by huge walls. There are five levels inside the temple, and one of the levels is situated underground. Dakshinamurti is the name given to the idol of Mahakaleshwar, and the deity faces the south.
Travel Talk
- Will Suggest 100
- My Favourite 56
- Been There 54
- Will Plan 52
- Will Avoid 22
Want to share your reaction with friends?
The temple is regarded as one of the twelve Jyotirlingas of India. There is a myth among the locals that the Prasad offered to the deity can be again re-offered, and this is believed to be a special feature performed only in this temple. The idol in this temple is of Omakareshwar Shiva and the deity is consecrated in the sanctum just above the Mahakal shrine. A huge fair takes place in the temple premises on the auspicious day of Mahashivaratri.


text:
Federal Business Opportunities (FedBizOpps) is the single point of entry on the Internet for federal buyers to publish and for vendors to find federal business opportunities over $25,000 across departments and agencies. Vendors can conduct ad hoc searches or set up automatic queries to notify them when opportunities meeting their criteria are posted.
The project was begun as a joint effort of the General Services Administration, the U.S. Department of Transportation, and the National Aeronautics and Space Administration, among others.


text:
Global Toronto is once again teaming up with the Toronto Professional Fire Fighters' Association this holiday season for the sixth-annual Toronto Fire Fighters' Toy Drive. Officially launching today, this charitable initiative will also feature a festive family-friendly event including a live broadcast of Global Toronto's News Hour at the Shops at Don Mills on Thursday, November 29.
Global Toronto is giving Torontonians the chance to celebrate this worthy cause, and spread good holiday cheer, with its special Toy Drive Live holiday event taking place at the town square area of Shops at Don Mills on November 29. Anchor Leslie Roberts will broadcast live from the event, along with Host Susan Hay and Global Toronto Meteorologist Anthony Farnell, who will conduct his nightly weather report on location.
"We are proud to once again lend our support to the Toronto Fire Fighters' Toy Drive and all they do for the community," says Ward Smith, Senior Director, News & Station Operations, Eastern Region. "Last year's event was a resounding success and brought viewers and families from all over the city together to get into the holiday spirit while supporting an immensely worthwhile cause."
The public is invited to join the fun and asked to bring along a new, unwrapped toy to the event for donation in exchange for a free burger from South St. Burger Co, drink from Aroma Espresso Bar, appetizer from P.F. Chang's China Bistro and cookie from The Bier Markt.
Families can drop off their holiday letters to Santa, enjoy a selection of holiday carols sung by the Crestwood School Choir, and catch the official lighting of two trees, taking place between 5:30 and 5:45pm. The Toy Drive Live event will also feature a booth where kids can dress up in fire gear, and a fun and interactive dance show for children, full of lights, music and energy. Attendees can also enter a draw to win a $500 Cadillac Fairview shop card.
News Hour's Susan Hay will kick off the Toronto Fire Fighters' Toy Drive this evening with live coverage during the News Hour broadcast from Station # 123 on Bond Street beginning at 5:30 pm. Coverage of the Fire Fighters' Toy Drive will continue on Global Toronto throughout the holiday season.
"The continued support from Global Toronto has been instrumental in the success of the Toronto Fire Fighters' Toy Drive as we move into our sixth year together," said Rick Berenz, President, Toronto Fire Fighters' Toy Drive. "Last year, the Toy Drive raised over 20,000 toys, something that wouldn't be possible without the help and the generosity of the citizens of Toronto. Thanks to them, we are able to give children in need from across the GTA a special gift this holiday season."


text:
Using the Internet to Serve Clients PDF
16 Learner Reviews -
- Course Delivery: On Demand
The real estate industry, along with many other industries, is being revolutionized by the Internet. As time goes on, increasing numbers of people gain access to the Internet and use it to satisfy their real estate needs. To avoid being left behind, real-estate professionals need to cultivate an online presence. In this module students will learn about the Internet and how it has affected the real estate industry. Students will also learn about the elements of Web sites and how to market themselves and their sites on the Internet. The final lesson teaches students to communicate effectively over email. The conclusion of this module presents real world dilemmas and applications of the information presented. As the student completes this module, he or she should try to paint a big picture of Internet issues, which the module will address with comprehensive content questions, practices and case studies.
Got questions? Contact us below or call 877-881-2235
Why choose 360training.com?
- Fast and easy course completion
- Get an education faster than at traditional colleges!
- 100% online - No classroom attendance required.
- Unlimited 24x7 online customer support
- Over 500,000+ certified nationwide
What your registration includes:
- Updated, relevant training content
- Unlimited, 24/7 toll free phone and online chat support
- Easily-accessible online platform
- Learn on your own schedule
16 Real Reviews From Actual Learners
The login experience was fast and easy. The learn as you grow works great with my busy schedule as a mom.Posted 8 months ago
usefullPosted 9 months ago
i am excited to get started on these courses. i will be writing an end review aswell.Posted 9 months ago
nPosted 9 months ago
I really enjoyed my classes and love the tools provided now that all my courses are done. They are very helpful in preparing me for my licensing exam!Posted 10 months ago
This site was well built and the information was great. I would like to see other supporting documents on best practices for marketing on the internet.Posted 11 months ago
THIRD TIME CUSTOMERPosted 11 months ago
Very informative and valuable for understanding how the internet functions in the Real Estate environment.Posted a year ago
THis is so easy and awesomePosted a year and 2 months ago
Concise and very informativePosted a year and 2 months ago


text:
The quest for justice and freedom for Jacob Ostreicher, an American businessman imprisoned without formal charges for 20 months in Bolivia, continued at a hearing today where American actor and activist Sean Penn came before the human rights subcommittee chaired by Congressman Chris Smith (NJ-04), a leading human rights advocate in Congress.
"On June 4th, it will be two years since he was imprisoned. Bolivian officials are employing delay tactics and giving excuses for his continued detention that we have heard before. No evidence whatsoever has been presented to indicate that Mr. Ostreicher is guilty of any crime. And there is no sign of the $27 million in assets from his rice operation that were confiscated. Perhaps this last fact is the real reason why Mr. Ostreicher still is not home with his family in the United States," said Smith, chairman of a U.S. congressional subcommittee that oversees international human rights. "It is very much a privilege to have Mr. Penn with us today, not only because of the fame that he has rightly garnered through his Academy Award-winning acting, and not only because of the highly commendable assistance he is bringing to the suffering people in Haiti through the relief organization that he founded, but also because of the extraordinary assistance that he has provided to Mr. Ostreicher, who he had never met and to whom he owed no obligation prior to being asked to assist with the case last fall. That assistance now includes joining us today to highlight Mr. Ostreicher's continued plight and to advocate for his freedom," Smith said. Click here to read the Chairman Smith's opening remarks.
Both Penn and Smith have visited Ostreicher. Penn attended a December bail hearing. Bail was denied for over 18 months, but finally granted in December. Smith visited him in June in the notorious Palmasano, prisoner-run prison, and met with Bolivian officials to release Ostreicher. In December, Smith led a bipartisan congressional delegation to continue to press for his freedom. Rep. Nydia Velázquez, who accompanied Smith in December, also attended today's hearing.
"As an actor, I have been in good movies and bad ones," Penn told the panel. "I have never seen a worse movie, nor more arch-villainy on such a caricature-ish or humanly diabolical level as I witnessed in that court room. Despite the clear and unequivocal arguments of innocence and more importantly, evidence of innocence, brought by Mr. Ostreicher's Bolivian defense team, the judge, under the clear intimidation of a panel of snickering, arrogant and hateful prosecutors would have none of logic nor law." Click here to read Mr. Penn's statement.
Smith has held two congressional hearings on the case, and also met with Ostreicher in June. Ostreicher is now especially frail, due in part to his hunger strike to protest his imprisonment. During his confinement, he has also begun treatment for Parkinson's disease. When meeting with him in December, Smith observed that Ostreicher's health has deteriorated significantly since their June meeting, and in particular saw a noticeable trembling of Ostreicher's hands which Smith had not observed during his previous visit.
During that June visit, Smith met with the Bolivian Minister of Government, Carlos Romero, to detail Ostreicher's story of injustice, including repeated court delays and complete lack of evidence against him. Romero told Smith he would investigate Jacob's treatment. In the past week, eight people involved in the case have been arrested on charges of corruption, including the legal adviser to the Ministry of Government, Fernando Rivera. Smith personally observed Rivera interfering in the June court proceedings. Bolivian media reported that Romero stated he first became interested in the case as a result of his meeting with Smith.
During his ordeal, Ostreicher has additionally endured the confiscation of all the assets of the rice farming business in which he was an investor, including millions of pounds of rice.
Smith originally became involved in the case in June 2012, when the human rights subcommittee he chairs held the first congressional hearing on Ostreicher's plight. Click here to read Chairman Smith's opening remarks from the June 2012 hearing.
Prior to his first visit to Ostreicher in the Palmasola Prison in Bolivia, Smith formally requested that U.S. Assistant Secretary of State of Western Hemisphere Affairs Roberta Jacobson personally intervene on Ostreicher's behalf. After visiting with Ostreicher at the prison, Smith met with high-ranking Bolivian officials, including Minister of Government Romero, Minister of Justice Cecilia Luisa Ayllon and Vice Foreign Minister Juan Carlos Alurralde, to discuss the case.
Minister Romero committed to Smith to personally look into the injustices and irregularities of Ostreicher's case. The efforts came to fruition in late November, and so far eight individuals involved in Ostreicher's persecution, including government legal staff, have been arrested.
In August of 2012, Smith held a second hearing on Ostreicher's case entitled "Seeking Freedom for American Trapped in Bolivian Prison." Chairman Smith also introduced "Jacob's Law" (H.R. 1778), based on Smith's prior legislation, the Belarus Democracy and Human Rights Authorization Act of 2011 (now P.L. 112-82, signed into law in January 2012). Jacob's Law would prohibit the travel of foreign officials and their families' to the United States if those officials are known to be complicit in the violation of fundamental human and due process rights of Americans imprisoned in their home country.
Source: http://chrissmith.house.gov/news/documentsingle.aspx?DocumentID=334712


text:
| View Exclusive AAUP Compensation Survey Data |
Faculty pay is up 2.2. percent, or 1.4 percent adjusted for inflation, new A.A.U.P. survey finds. Despite modest gains, association says professor pay can't be blamed for tuition hikes. Searchable database by institution available exclusively here.
Writing instructors at Conference on College Composition and Communication talk about teaching about racism and white privilege -- and the political and career risks they face for doing so.
Presidents overwhelmingly say they should have more input in faculty hiring and tenure decisions. But just how much say should they have?
U. of North Georgia case raises key questions: Is rudeness grounds to revoke tenure? Should professors' jobs be at risk over criteria in employee handbook that are not in faculty handbook?
U. of Tennessee walks back -- at least in terminology -- from a proposal to "de-tenure" faculty members as part of new business plan. But the policy idea may well remain alive.
UW-Madison chancellor comes under fire for recently admitting she matches outside faculty offers with course load reductions. Is there anything wrong with the practice?
A prominent professor uses a disciplinary meeting to discuss his struggles with depression -- and encourages others in academe to talk about mental health issues.
Yale professors oppose draft policy on their conduct that they say is vague on what they could be punished for and what the sanctions would be -- not to mention that it excludes administrators.
Historians condemn recent attempt by Oklahoma legislature to defund AP American history curriculum for being too "negative."
Report seeks a broad rethinking of the structure of professors' jobs, with a strong emphasis on academic freedom and equitable treatment, but an openness to radical change.
Inside Higher Ed
1015 18th Street NW
Suite 1100
Washington, DC 20036
Ph: 1-202-659-9208
Fax: 1-202-659-9381
1015 18th Street NW, Suite 1100 | PH: 1-202-659-9208
Copyright © 2017


text:
On a new note I have begun eating right and exercising. I have learned that exercising is fun. I may not be the ideal woman now but I guarantee you that I will be fit before you know it. If you aren't willing to stick around and see me shine then you're a waste of my time.
Lastly....if you message me talking about my breasts or tongue ring the conversation is over immediately. I can't help that I have large breasts and that it gets uncomfortable to wear t shirts so I wear tank tops. So just because I have a lot of cleavage doesn't mean anything.
I mainly want to go to New Zealand, Ireland, France, Italy, Germany, Greece, and Japan.
My laugh
From country to rock or from pop to piano i love ALL music
I also love horror films and action and comedy
My favorite shows are definitely Doctor who and Once Upon A Time. Other shows I enjoy though are Reign, The Flash, Arrow Supernatural, Jane the virgin, The 100, sleepy hollow, Glee, New Girl, Bones, Castle, Adventure Time, Avatar The Last Airbender, Legend of Korra, SpongeBob, Teen Titans, American Dad, Family Guy, Futurama, Psych, Buffy the Vampire Slayer, Angel....and many more lol I'm a t.v. girl
I'll try almost anything once but if I had to choose a favorite I would have to say Chinese and Italian....but i hate seafood
Honestly there's not much more you can do in this small town.