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We assessed whether insufficient sleep is associated with pre-hypertension in healthy adolescents.
Cross-sectional analysis of 238 adolescents, all without sleep apnea or severe co-morbidities. Participants underwent multiple day wrist actigraphy at home to provide objective estimates of sleep patterns. In a clinical research facility, overnight polysomnography, anthropometry, and 9 blood pressure (BP) measurements over 2 days were made. Exposures were actigraphy-defined low weekday sleep efficiency, an objective measure of sleep quality (low sleep efficiency ≤85%) and short sleep duration (≤6.5 hrs). The main outcome was pre-hypertension (≥90th%ile for age, sex, and height), with systolic and diastolic BP as continuous measures as secondary outcomes. Pre-hypertension, low sleep efficiency, and short sleep duration occurred in 14%, 26%, and 11% of the sample, respectively. In unadjusted analyses, the odds of pre-hypertension was increased 4.5-fold (95% CI: 2.1, 9.7) in adolescents with low sleep efficiency and 2.8-fold (95% CI: 1.1,7.3) in those with short sleep. In analyses adjusted for gender, BMI percentile and socioeconomic status, the odds of pre-hypertension was increased 3.5-fold (95% CI: 1.5. 8.0) for low sleep efficiency and 2.5 fold (95% CI: 0.9, 6.9) for short sleep. Adjusted analyses showed that adolescents with low sleep efficiency, on average, had a 4.0 ± 1.2 mm Hg higher systolic BP compared to other children(p<0.01).
Poor sleep quality is associated with pre-hypertension in healthy adolescents. Associations are not explained by socioeconomic status, obesity, sleep apnea or known co-morbidities, suggesting that inadequate sleep quality is associated with elevated blood pressure.
Hypertension is an increasingly prevalent health problem in adults and adolescents alike. Between 1988 and 1999, pre-hypertension (i.e., a blood pressure {BP} ≥ the 90th percentile for height, age, and gender) and hypertension were estimated to increase in children by 2.3% and 1%, respectively. 1 Childhood hypertension is associated with hypertension in adulthood, a risk factor for cardiovascular disease incidence and mortality. 2-5 It is also associated with end-organ damage in both children and adults, notably left ventricular hypertrophy. 6, 7
Several studies have implicated insufficient sleep as a risk factor for hypertension in adults 8-12. Although the etiology is unclear, experimental studies indicate that shorter sleep results in metabolic and endocrine dysfunction that may contribute to cardiovascular disease. 13-17 Studies in both adult and pediatric populations also have reported associations of shorter sleep duration to obesity and impaired glucose tolerance. 14, 18, 19 These findings have a potentially large public impact given the frequency of sleep curtailment. 20
Few studies have addressed the relationship between sleep and hypertension in children. A higher level of diastolic, but not systolic blood pressure (BP) was reported in children with obstructive sleep apnea compared to primary snorers. 21 The Tucson's Children's Assessment of Sleep Apnea Study found that elevations in systolic and diastolic BP were independently associated with sleep efficiency, respiratory disturbance index (a measure of sleep apnea), and obesity in 230 children aged 6 to 11 years.22 To our knowledge no studies have examined the association between insufficient sleep and BP in adolescents free of sleep apnea. In this report, we examine the relationship between pre-hypertension and systolic and diastolic BP levels with objective measures of sleep quality and duration in a community-based cohort of adolescents. First, we hypothesize that adolescents with poor sleep quality or short sleep duration will be at increased odds of pre-hypertension. Second, we posit that adolescents with short sleep duration or poor sleep quality will have higher systolic and diastolic blood pressure readings on average compared to adolescents with better quality sleep. We excluded adolescents with clinically significant levels of sleep apnea to minimize the influence of this exposure on BP and sleep duration measurement.
The sample was derived from the Cleveland Children's Sleep and Health Study (CCSHS), a longitudinal cohort study. Data for this analysis are from 238 adolescents free of severe illnesses who participated in an examination performed 2002-2006 aimed at participants aged 13 to 16 years. Details of the study population have been reported elsewhere25,23 and are reviewed in an On Line Supplement.
Adolescents underwent 5 to 7 day wrist actigraphy and completed a daily sleep log at home during the week prior to a clinical research center exam and when free of acute illness. After this period of in-home monitoring, participants were studied in a dedicated clinical research center where overnight polysomnography, physiological and anthropometric assessments were performed using a standardized protocol .23,24 Examinations at the research center began at approximately 17:00 and ended the following day at 11:00. Informed consent was obtained from the child's legal guardian and written assent was obtained from the child. The study was approved by the governing institutional review board.
Sleep wake estimation was made using wrist actigraphy (Octagonal Sleep Watch 2.01; AMI, Ambulatory Monitoring Inc., Ardsley, NY) analyzed using the Action-W software and the Time Above Threshold algorithm. 25 Using weekday data (minimal 3 days), mean sleep duration and mean sleep efficiency, an objective measure of sleep continuity and quality, defined as the percentage time in bed estimated to be asleep (i.e., total time estimated to be asleep/total time in bed for the major sleep period) *100) were calculated. Adolescents with a sleep efficiency ≤85% were considered to have low sleep efficiency. Given the lack of data on cutoffs for defining "short sleep duration" in this age, we used the lowest decile of mean sleep duration on weekdays to define short sleep duration, which approximated 6.5 hours.
Three BP readings were obtained at each of three times (21:00 [supine] the night of the polysomnography, 08:00 [supine], and 9:30 [sitting] the following morning) following published guidelines. 23 After a 10 minute rest period, BP was obtained using a calibrated sphygmomanometer by trained nurses. The mean systolic BP and diastolic BP values used in primary analyses were based on the average of all nine measurements. Pre-hypertension was identified if the systolic and/or diastolic BP ≥90th percentile for age, gender, and height. 4 Hypertension (HTN) was defined as systolic BP or diastolic BP ≥ 95th percentile. One adolescent using anti-hypertensive medication was classified as having HTN.
A rigid stadiometer was used to measure height, and a calibrated digital scale to measure weight. Body mass index was calculated by dividing the weight in kilograms by height in meters squared and converted into age and sex adjusted percentiles (http://www.cdc.gov/growthcharts/). Overweight was defined as a BMI ≥ 95th percentile. Adolescents who were reported to snore loudly at least 1-2 times per week during the past month were categorized as snorers. The apnea hypopnea index was defined as all obstructive apneas and l hypopneas with a ≥ 3% desaturation per sleep hour from the polysomnogram. Socioeconomic status (SES) measures included parent report of educational level and family income. Additionally, the census tract of the child's residence when initially enrolled in the study was linked to the corresponding 2000 U.S. Census Bureau database, and median income of the census tract was ascertained (http://wagda.lib.washington.edu/data/type/census/). A composite SES z-score was created by averaging the sample z-scores for these three measures. Tanner staging was performed by a physician to determine pubertal status 26, 27 . Preterm status was ascertained from birth records and defined as a gestational age <37 weeks. Attention Deficit Hyperactivity Disorder (ADHD) was defined as parent reported doctor's diagnosis of ADHD and either condition currently present or medication/stimulant use for ADHD during the past year. Using a standardized questionnaire, adolescents reported the frequency with which they consumed caffeine after 6 PM in the evening during the past month; those reporting "frequently" or "always" consuming caffeine were coded as consuming caffeine in the evening.
Between-group differences for the binary outcome, pre-hypertension, were assessed using the Pearson chi-square test for categorical variables, the two-sample t-test for normally distributed variables, and the Wilcoxon Rank-Sum test for non-normally distributed measures. To assess confounding, associations between the primary exposures, low sleep efficiency (≤85%) and short sleep duration (≤6.5 hrs), and sociodemographic characteristics were also examined. Spearman and Pearson correlations assessed the strength of the linear relationship between sleep characteristics obtained from polysomnography and actigraphy. Logistic regression analyses were used examine whether adolescents with short sleep duration or low sleep efficiency were at increased odds of pre-hypertension. Given the relatively small number of adolescents with pre-hypertension, covariate adjustment was limited to the SES z-score and the 2 variables most strongly associated with pre-hypertension: gender and BMI percentile. Multiple linear regression, adjusting for age, gender, race, preterm status, BMI percentile, and SES z-score, was used to examine the linear associations between sleep duration or sleep efficiency with continuously measured systolic and diastolic blood pressure levels. Additional analyses included low sleep efficiency from the polysomnography as the exposure. Residual confounding by snoring or the apnea hypopnea index also was assessed by including these measures as covariates in the adjusted analyses.
The authors had full access to and take full responsibility for the integrity of the data. All authors have read and agree to the manuscript as written.
Characteristics of the analytic sample are shown in Table 1. The average participant was age 13.7 ± 0.7 years. As designed, the sample had an approximately 50% representation of boys, African Americans and children born prematurely. One fifth of the sample was overweight. Approximately one-fourth reported their household income as less than $20,000 per year. Sixty-one adolescents (26%) had low sleep efficiency. Average weekday sleep duration was 7.71 hours and 11% of the sample slept ≤ 6.5 hrs.
Sample characteristics stratified by pre-hypertension are also shown in Table 1. Overall, 33 children (14%) met the criteria for pre-hypertension, including 19 who had pre-hypertension and 14 who were hypertensive. Compared to normotensive adolescents, those with pre-hypertension tended to have a higher proportion of males, higher BMI and were more frequently from neighborhoods with a low median income (p-values between 0.05 - 0.10). Both low sleep efficiency (p<.0001) and short sleep duration (p = 0.06) were more than two-fold more prevalent in those with pre-hypertension compared to normotensive adolescents.
The distribution of various BP measures is further detailed in Table 2. Using the mean of nine BP readings, approximately 11% of the sample was classified with elevated systolic BP and 5% with elevated diastolic BP. All measures of systolic BP were significantly higher among the adolescents with low sleep efficiency compared to those with higher sleep efficiency. Adolescents with low sleep efficiency also had a higher prevalence of elevated diastolic BP and had higher 08:00 diastolic BP values. Adolescents with short sleep duration did not differ from those with longer sleep duration in regards to systolic BP, but had a higher average diastolic BP and higher prevalence of elevated diastolic BP (24.0% vs 2.4%; p<0.001).
To assess confounding, associations among the sleep exposures and sociodemographic characteristics were examined (see on-line supplement). Adolescents with low sleep efficiency had a higher BMI, were more often male, and were from households with lower incomes and lower levels of caregiver education. These characteristics were not significantly associated with short sleep duration. Approximately two-thirds (68.0%) of adolescents with short sleep duration also had low sleep efficiency, while 27.9% of adolescents with low sleep efficiency also had short sleep duration. The correlation between mean weekday sleep efficiency and sleep efficiency from the night of the polysomnography was low (r= 0.13, p=0.04), as was the correlation between mean weekday sleep duration and sleep duration from the night of the polysomnography (r=-0.06, p=0.37). Approximately one-third (32.8%) of adolescents with low sleep efficiency based on actigraphy also had low sleep efficiency from the polysomnography.
The results of the logistic regression models of the association between each sleep measure and the odds of pre-hypertension are shown in Tables Tables3a3a and and3b.3b. After adjusting for gender, BMI percentile and SES z-score, those with low sleep efficiency had 3.5 times the odds of pre-hypertension compared to those without low sleep efficiency (95% CI: 1.54, 7.96). Short sleep duration was associated with a 2.8-fold increased odds of pre-hypertension in unadjusted analyses (95% CI: 1.07, 7.34), but this association was modestly attenuated after adjusting for gender, BMI percentile and SES z-score (OR: 2.54; 95% CI: 0.93, 6.90).
The unadjusted and adjusted associations between continuously measured systolic and diastolic BP levels with sleep efficiency are shown in Table 4. After adjusting for age, gender, race, term status, BMI percentile and SES z-score, the model predicts that each 5 percentage increase in sleep efficiency was associated with a 1.5 ± .40 mmHg decrease in systolic BP (p<.001). Weaker associations were observed between sleep efficiency and diastolic BP; i.e., each 5 percentage increase in sleep efficiency was associated with a 0.65 ± .35 decrease in diastolic BP (p=.05). When modeling low sleep efficiency as a dichotomous exposure, the adjusted model estimates that adolescents with low sleep efficiency had a mean systolic BP that was on average, 3.99 ± 1.24 mm Hg higher compared to those with higher sleep efficiency (p=0.002). Including sleep duration as a continuously measured covariate did not alter the primary associations of sleep efficiency and BP (data not shown).
Similar to the models of pre-hypertension, sleep duration was more weakly associated with continuously measured systolic and diastolic blood pressure compared to sleep efficiency (Table 5).
The primary analyses also were repeated with low sleep efficiency ascertained via polysomnography as the exposure. Consistent with the results of the primary analysis, after adjusting for gender, BMI-percentile and SES z-score, those with polysomnography sleep efficiency ≤85% had nearly 3 times the odds of pre-hypertension as those with better sleep (OR=2.83, 95% CI: 1.28, 6.24). Also consistent with the results of the actigraphy-defined sleep exposures, in adjusted analyses, each one percentage increase in sleep efficiency was associated with a 0.20 ± .06 decrease in systolic BP (p<.001). Similarly, those with low polysomnography sleep efficiency had systolic BP that was 3.26 ± 1.25 mm HG higher on average compared to those with better sleep (p=0.01).
Although analyses were restricted to children without clinically significant sleep apnea, additional analyses assessed potential residual confounding by snoring or the apnea hypopnea index (i.e., in an apnea hypopnea index range of 0 - 4.9). The results show that loud snoring was not significantly associated with pre-hypertension, systolic BP or diastolic BP. In contrast, while the apnea hypopnea index does not confound the association between the outcomes and the sleep exposures, it was associated with increased odds of pre-hypertension after adjusting for low sleep efficiency, gender and BMI percentile; i.e., for each one-unit increase in the apnea hypopnea index, the odds of pre-hypertension increased by 47% (OR=1.47, 95% CI: 1.00, 2.17). Similarly, the apnea hypopnea index was significantly associated with systolic BP in adjusted models; after adjusting for subject characteristics and low sleep efficiency, for each one-unit increase in apnea hypopnea index, mean systolic BP increases by 1.65 mm Hg on average (p=0.009).
To our knowledge, this is the first reported association between low sleep efficiency and short sleep duration objectively measured in the child's usual sleep environment with elevated BP (pre-hypertension or hypertension) in adolescents without clinically significant levels of sleep apnea. Specifically, adolescents with poor sleep quality, as measured by a sleep efficiency of ≤ 85%, were at 3.5-fold increased odds of being pre-hypertensive or hypertensive. Similar findings were observed when single night polysomnography was used to quantify sleep efficiency. The association between low sleep efficiency and pre-hypertension persisted even after adjusting for gender, SES and adiposity. The results did not appreciably change after adjusting for snoring or the apnea hypopnea index. Short sleep duration was also associated with a 2.5-fold increase in odds of pre-hypertension or hypertension. However, it was not clear if this association was attributable to the low sleep efficiency found in a majority of the adolescents with short sleep duration.
In adults, poor sleep quality identified by questionnaires has been reported in association with an increased prevalence of hypertension 12 and an increased rate of "non-dipper hypertension." 28 However, poor sleep quality in adults often occurs in the presence of primary sleep disorders, such as sleep apnea or insomnia, or secondary to numerous co-morbidities. Therefore, adult studies reporting associations with disturbed or reduced sleep and hypertension have been cautiously interpreted due to concerns over residual confounding. 10 One large prospective study reported associations of short sleep duration in women but not men 8, while another study showed no association of hypertension and sleep duration in the elderly, a group with a high prevalence of morbidities. 29 Since adolescents with major co-morbidities, including those with clinically significant levels of sleep apnea, were excluded from our analyses (to minimize confounding and reduce measurement error), it is unlikely that major confounding due to medical illnesses, medications, or sleep-related hypoxemia explains the strong association between low sleep efficiency and elevated BP. Given that the association between BP and low sleep efficiency persisted even after adjusting for average sleep duration, our findings also suggest that recurrent arousals or awakenings from sleep (which reduce sleep efficiency) are associated with elevated blood pressure. Our findings are consistent with a report from a sample of pre-adolescent children studied with single night polysomnography which demonstrated an association between low sleep efficiency and elevated BP after adjusting for the apnea hyponea index. 22
The 3.5-fold odds of pre-hypertension or hypertension in children with low sleep efficiency, if causal, suggests associations with a potential large public health impact. Although the overall prevalence of low sleep efficiency in general pediatric samples is unknown, our prevalence of 26% is likely an under-estimate given the exclusion of children with sleep disorders and significant co-morbidities. Our finding of an increased prevalence of low sleep efficiency among vulnerable population subgroups, such as poorer children and those of minority ethnicity, may be of special concern since these groups are known to be at risk for hypertension and other adverse health outcomes.
Low sleep efficiency was associated with an average adjusted increase in systolic BP of 4 mm Hg. Although limited data are available in children to interpret the clinical significance of this absolute elevation, large cohort studies suggest a log-linear increase in morbidity in association with incremental changes in systolic blood pressure. 30
Short sleep duration was associated with a 2.5-fold increased odds of pre-hypertension, an association partly attributable to low sleep efficiency. Short sleep duration has been increasing in all ages31 and is also associated with an increased risk for obesity. 13, 16-18 Efforts to optimize sleep in childhood, thus, may improve the BP profile of children through obesity dependent and independent pathways. Further work is needed to dissect the relative influences of sleep curtailment from sleep disruption on health outcomes, which will be important in directing whether future interventions would be best directed at improving sleep time, sleep consolidation, or both.
The etiology of low sleep efficiency in healthy adolescents is unclear. Sensitivity analyses did not indicate an association between low sleep efficiency with common childhood disorders such as asthma or attention deficit hyperactivity disorder or with caffeine or tobacco use, nor were these variables confounders in the association between sleep efficiency and BP (data not shown). It is possible that unknown psychological disorders may have confounded our results, but this seems unlikely given the strong associations and community sampling design.
Although children with significant sleep apnea were excluded from our analyses, the apnea hypopnea index (in a range of 0 to 4.9) was significantly associated with pre-hypertension and systolic blood pressure after adjusting for sleep efficiency. The latter suggests that even mild sleep disordered breathing may contribute to abnormal blood pressure levels, a result consistent with reports of more severely affected children from sleep clinic samples. 21
Strengths of this report are the inclusion of a community-based sample of children, minimizing referral biases, and the use of objective measures of sleep duration and multiple measures of BP, minimizing measurement error and reporting biases. By characterizing numerous risk factors and co-morbidities, we were able to restrict the analytical sample to children without disorders likely to confound associations with sleep quality. Although former pre-term children were over-represented by design, there was no evidence of any differences in the exposures, responses, or associations between preterm and full term children, suggesting our results should be generalizable to other pediatric samples.
There are no established cutoffs to define thresholds of sleep duration or sleep efficiency that increase morbidity in adolescents. In adults, sleep durations of < 6 hrs have been associated with a variety of adverse health outcomes 15, 19, 32, 33 and sleep efficiencies of < 85% are considered low. Our choice for defining short sleep duration as less than 6.5 hrs was to approximate the cutoff associated with hypertension risk in adults, 10 which, in our sample, represented the lowest decile. However, examination of a larger sample may permit a more comprehensive assessment of dose-response and threshold levels for each sleep exposure.
A limitation of this cross-sectional study is that BP status was determined from measurements made on two consecutive days. Since BP may vary from day to day, repeated measurements over time are needed to identify children with persistent elevations in BP. Another limitation is that the reported associations do not provide proof of causality. We also cannot exclude the possibility that elevated BP operates as a risk factor for poor sleep. It is important, however, to interpret our findings in light of the biological plausibility of the observed associations and experimental data that show acute effects of sleep disruption on BP. Mechanisms linking poor sleep efficiency or sleep deprivation with hypertension may be through disruptions in cortisol secretion 19, 34, 35 and stimulation of the renin-angiotensin system and sympathetic nervous system, as measured by increased secretion of catecholamines 36 and abnormalities in sympathovagal balance, 37 and through abnormal secretion of vasoactive hormones, including endothelin, vasopressin, and aldosterone. 38 Experimental sleep disruption has been associated with elevated BP in sleep in normal subjects. 39 While some experimental models suggest that sustained elevations in BP require sleep fragmentation to occur in a background of intermittent hypoxemia 40 (as occurs with sleep apnea), sleep fragmentation may be associated with elevated BP even in adults with a low apnea hypopnea index 41 or with simple snoring 11. Prospective and interventional studies are needed to provide further evidence of causality and also to address whether improving sleep quality and duration reduce BP and risk of hypertension.
In summary, extensive analyses using objective measures of sleep quality and duration and multiple measures of BP provide evidence for a strong association of low sleep efficiency with increased risk of pre-hypertension and hypertension in a healthy sample of adolescents. Our data suggest that low sleep efficiency may more consistently be associated with pre-hypertension than short sleep duration. Future research is needed to address whether prevention of hypertension in children should not only include weight management and exercise, but also include optimization of sleep. Our data underscore the need to monitor quantity and quality of sleep as part of health supervision in children.
Funding: Supported by grants: NIH HL07567, HL60957, RO1 NR02707, M01 RR00080 and 1U54CA116867.
Disclosures: Carol Rosen has received a Subcontract from Advanced Brain Monitoring, Inc to provide clinical research services funded through a NIH SBIR. Susan Redline has received a Subcontract from Cleveland Medical Devices Inv to provide clinical research services as part of a NIH SBIR. S Javaheri and Amy Storfer Isser do not have any disclosures.
Clinical Implications:
Childhood hypertension is a risk factor for adult hypertension and for target-organ damage. Early recognition and intervention of childhood hypertension are believed to be important in reducing risk of cardiovascular morbidity in adulthood. Traditional approaches for intervention focus on the role of overweight as a contributing cause of hypertension, and include weight reduction, increased physical activity and nutritional changes. The current report identifies a significant association between increased blood pressure and poor sleep quality (i.e., increased wake time during the sleep period), found in 26% of a community sample of adolescents. Independent of obesity, gender and socioeconomic status, and unrelated to sleep apnea, adolescents with poor sleep had a 3.5 fold increased risk of pre-hypertension or hypertension. This finding suggests that approaches for optimizing sleep quality and duration in children may complement other behavioral approaches for preventing or treating pediatric hypertension. Monitoring sleep quality and duration in children as part of their health supervision may help identify children who are at risk for both sleep problems and hypertension, and who would benefit from behavioral interventions aimed at improving sleep.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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The Spirits Await...
Scratches are being carved into the dust-covered floor by some unseen force. The markings look like those of a giant bird. The boys stand in a phalanx, Adrian at the center. On his right stands Boylan, on his left, Welcome. They all watch the circles being carved into the floor. The second circle is finished. Another circle begins, concentric, one ring closer.
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Not a circle this time -- letters. Carved in the space between the third and fourth rings, one ragged letter at a time.
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[PROJECT] Sustain-ALGae - Sustainable Integrated micro-Algae Culturing System (Sustain-ALGae)
Start date: 2016-08-01, End date: 2016-12-31
Truly high profits wait for those that take algae culture to the next level. This has been known to the food and animal-feed industry for some time, as bio-mass produced by microalgae is both immensely valued and highly priced. Bioactive compound of the micro-algae in question...
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[PROJECT] ICECHILLING - Ice Chilling System for Enhanced Food Cooling
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A rare opportunity to drive a circle route, completed in 2009, on southern Vancouver Island's western coast. Travel through mystical, moss-draped and supersized temperate rainforest with some of tallest and oldest trees in the country.
Mystic Beach Hike To Port RenfrewVitaNovember 4 / 2016
To really experience Port Renfrew, one must stay at Wild Renfrew. Featuring a cluster of private cabins along the rocky shores, you get five-star amenities (think 400 thread count sheets, a full-sized kitchen and stunning views), we sense it's going to get very busy as word travels. Just steps away at the Renfrew Pub, you'll find gourmet burgers, seafood and salads, along with the friendliest locals, and craft brews on tap. - See more at: http://www.vitadaily.ca/travel/vancouver-island-in-4-days-1.2275120#sthash.RbgjxsXt.dpuf
Exploring the Wild Side of Port RenfrewTourism VictoriaNovember 4 / 2016
Port Renfrew is a small town on the west coast of Vancouver that has been home to tall trees, deep roots and families for generations. Approximately 2 hours' drive west of Victoria, Port Renfrew is the perfect place to go wild: go off the grid and unwind, surrounded by ancient forests and rugged coastline.
Port Renfrew's Only Penthouse RentalLuxury BCNovember 4 / 2016
For those that do know I've been working on launching a luxury travel agency here in BC and we're just about to launch. I've also been studying my travel notes and learning what new places have been built in the past few years and came across this. Only two hours away by car from Victoria sits the Viewpoint Penthouse in Port Renfrew and it's a spectacular staycation spot right on the ocean.
Overwhelming beautyThe Globe and MailNovember 4 / 2016
Almost every inch of Port Renfrew, B.C., inspires awe – from the tiniest starfish trapped in a tidal pool to the hulking growths of 'Canada's gnarliest tree.' Good thing you'll have nothing else to do but take it all in


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-Based on the Catalyst 4.12 Beta drivers.
-New Radlinker installation method, now it should install correctly every time.
-Fixed gamma issues with color control panel.
-WMV acceleration is now off by default, you can turn it on in the Options panel.
-New quick shortcut for Radlinker, just right click your desktop and go directly to all the Advanced 3D settings.
-Fixed Standby/Suspend/Hibernation bug.
-Added a lot of new resolutions for wide screen monitor/dfp users.
-Fixed the Forced Anisotropic settings, now they should not reset to Performance mode.
-Removed the special Counter Strike OpenGL from the package, now that CS:S is available, this is no longer necessary.
-Fixed some uninstall issues, now the drivers should completely be removed if you select to do so.
Read me!
Hersteller-Seite: www.omegadrivers.net
Download: Software-Download (16.8MB)


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Submitted by prproofread • April 6, 2013 www.microsoftarticles.info
From such discussion, the significance of the problem and the aspects of it that need to be studied should be derived. That information supports the purpose of the study and, based on it, the research questions are formulated.
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Academy Awards Guide
Academy Awards Guide from Overstock.com. Our guides provide customers with information about the Academy Awards.
Porky's a true story about a high school in the 50's in Broward County...
ITEM#: 10386349A raunchy, irreverent comedy classic released in the early 80s to set the tone for all other teen flicks of that era, PORKY'S takes a look at the sex lives of a group of teenage boys in 1950s Florida in all their obsessive, unfulfilled glory. Pee Wee, the main character in this group of six Angel Beach high schoolers, is so named for the size of his appendage; nonetheless, he wants nothing more than to lose his virginity. All six spend most of their time devising easy ways to score and spying on coeds in the shower, taking breaks only to insult their large dictator-like teacher, Ms. Ballbricker, and play pranks on each other. They devise a plan to take a trip to a divey strip club in the Everglades called Porky's, where they are sure to get some action; unfortunately, owner Porky doesn't much care for the underage likes of them, and after humiliating them and stealing their money, he kicks them out. The boys are deflated, but not for long! What follows is one of the most elaborate and uproarious revenge plots ever committed to film, one that cemented this movie's place within the canon of comedy forever. Director Bob Clark culled his own childhood memories to write the film over a period of 15 years, and the personal quality as well as the elements of racism that were characteristic of post-WWII Florida, lend the film an authenticity that rises above the mere sex comedy. It also stars Kim Cattrall, who went on to star as Samantha in SEX AND THE CITY.
|Fox Home Entertainment
|Extra Info
|Holiday O-Ring Packaging
|5.5" x 0.5" x 7.5" WxHxD
|0.24 lbs
|Kim Cattrall, Nancy Parsons, Dan Monahan, Kaki Hunter, Susan Clark, Alex Karras, Wyatt Knight, Scott Colomby, Mark Herrier, Roger Wilson, Cyril O'Reilly
|Bob Clark
|Country of Origin
|United States
Porky's a true story about a high school in the 50's in Broward CountyRead More
Academy Awards Guide from Overstock.com. Our guides provide customers with information about the Academy Awards.
Looking for the perfect Valentine's Day movie to watch this year? We've picked the best of classic, manly, RomCom, devastatingly sad, and guilty pleasure Valentine's Day flicks.
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Porky's (DVD)
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text: (I already know that some of you will say that this is not an important mystery, compared to others still left on the table ok?)Anyone still wonder who designed/built the Lamp Post my $$$ was on Faraday or Chang, because it was how the DI found the island. But they'd have to some how have previous info about the island.


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I have been working with macro recording software for windows that runs a specific application every 15 minutes, generate a report, and save the report to a network folder. So far I have not been very pleased with the inconsistency in how the macro recording software works. It will run a number of times successfully, and then out of the blue it will error.
If you are using macro recording software for windows, what do you use, approximate cost, and your opinion?
Thank you.
This discussion has been inactive for over a year.
You may get a better answer to your question by starting a new discussion.


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98KUPD Holmberg's Morning Sickness is Arizona's #1 Morning Show. John Holmberg attempts to both entertain and disturb as many listeners as possible with assistance from Brady Bogen, Creepy E, and Dick Toledo. Tune into 98KUPD weekdays 5:30a-10a.
Guadalupe Squares Friday July 21, 2017 - Today's Squares guests included... Show More


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Online Graduation Day-2017 Registration
Admission @ RVCE 2017-2018.
RVCE FHWS-2017 (Germany)
Fast Track-2017.
Inauguration of 1st Year B.E. Class.
Higher Semester Fees 2017-18.
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B.E. & B.Arch Rank List-20171st Year BE Inauguration 2017-18NIRF-2017 Rankings RVCE DataFees details for Admission to 1st year BE (2017 - 18)


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St. Paul hounds nominee for Labor
WASHINGTON — Thomas Perez, nominated by President Obama to be Labor secretary, clashed with Senate Republicans on Thursday at his confirmation hearing over decisions he made as the Justice Department's top civil rights lawyer.
Republicans on the Senate Health, Education, Labor and Pensions Committee criticized Perez's role in persuading the city of St. Paul to drop a Supreme Court case that lawmakers said would have undermined a government enforcement tool in housing discrimination cases.
Sen. Lamar Alexander of Tennessee, the panel's top Republican, said Perez engaged in "an enormous amount of wheeling and dealing" by agreeing to keep the Justice Department out of two unrelated cases against St. Paul that might have reaped as much as $200 million for the U.S. Treasury.
When Perez said the Department of Justice was acting as a guardian of civil rights in negotiating the deal, Alexander retorted: "The DOJ is a guardian of the taxpayers as well, is it not?"
Republicans focused their criticism of Perez, a child of Dominican immigrants who would be the only Hispanic in Obama's second-term Cabinet, on what they say are ideological decisions he made as head of the civil rights division. A committee vote on the confirmation will be on Thursday, Chairman Tom Harkin, D-Iowa, said when the hearing ended.
Sen. David Vitter, R-La., has vowed to block the nomination over separate questions related to the nominee's work in enforcing voter registration laws, meaning Perez probably will need at least 60 votes to overcome a filibuster. Democrats control 55 Senate seats.


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3.6V Lithium Computer Backup Batteries - Half AA N
TB-SB1770 These high capacity batteries are used in many desk top and notebook computers to retain date, time and configuration information while the computer is switched off. They are also useful where long shelf life is important or when the battery is to be fitted into difficult or sealed access areas. Storage life is up to 10 years. Note: These are not rechargeable Size Capacity Max Current Dia Height Connect SB-1771 Half AA 900mAh 50mA 14.5mm 25mm Nipple


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We're upgrading our systems.
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Life insurance quotes
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African, Belizean & Caribbean Mennonite Mission Association, USA is a registered constituency group of Pacific Southwest Mennonite Conference. It unites African, Belizean & Caribbean Mennonite Churches in the United States of America which seek to bring together pastors and leaders with the purpose of sharing resources with one another and collaborating with other organizations for church planting, evangelism of love and non-violence, and mission within North America and overseas within the holistic Anabaptist and Mennonite framework.
- Pursuit of Anabaptist-brand of evangelism, church-planting and mission both locally and overseas, and deliberate effort to disciple and make all the converts ardent followers of Jesus Christ
- Collating and sharing all kinds of resources with congregations that engage in both church planting and mission both locally and globally
- Working in collaboration with mission organizations within the Mennonite Church as we are here to complement one another and not to compete in carrying out God's work on earth
Bishop Charles Opong – President
Pastor Nehemiah Chigoji – Secretary
Pastor Grace Pam – Treasurer
Pastor Helen Mfliwakanda – Financial Secretary
For information on meeting times and other inquiries, please call Helen Wall at 323 229 2235 or Joan Montgomery at 323 570 7421.


text:
Category: Stock Footage
VideoHive Blue Waves 1248258
Stock Footage \ Motion Graphic \ Backgrounds \ Abstract
Particles \ Particle \ Effects \ Seamless \ Repeats \ Created \ Motion \ Background
Motion Graphic - Blue Waves 1248258 by cmadden @ VideoHive
Stock Footage \ Motion Graphic \ Backgrounds \ Abstract
Blue particles and waves. 30 second particle loop that repeats seamless.
Created in After Effects CS4 .
Alpha Channel: No; Looped Video: Yes; Frame Rate: 29.97; Resolution: 1280x720; Video Encoding: Photo - JPG; File Size: 85mb; Total Clip(s) Length: 0:30.
Blue Grace; Grace; Gold Dollar Signs; Gold Fountain; Snowfall; Portal Particles; Snow Flakes.
Keywords: after effects, background, blue, loop, motion, particle, particles, subtle, waves.


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Friedland had studied in India with Neem Karoli Baba (Maharaj-ji), who had been the guru to much of the sixties hippie movement.Ugg Australia Outlet Locations" "And she hasn't asked you to use them for this?" "No.Ugg Lo Pro Button "The smell and behavior wasn't an issue with me," he said. "Go and pull it. Eventually the engineer found an even better way to perform the function that Jobs had criticized. Jobs had resisted, thinking that BASIC was all the Apple II needed, but he told Atkinson, "Since you're so passionate about it, I'll give you six days to prove me wrong.Read more › 5 s Yes No 10 of 10 p Excellent product, while not so warm as resolute, expedition etc CG parkas Mike on October 22, 2013 Bought it 4 years ago, as with all CG-ses, a bit oversized. Ugg Boots Sale Cheap Ugg Boots His parents were barely making ends meet, but by this point there was little doubt that they would eventually bend to his will.Ugg Official Jobs had resisted, thinking that BASIC was all the Apple II needed, but he told Atkinson, "Since you're so passionate about it, I'll give you six days to prove me wrong. "Rub that and see how thick and warm it is," she said.," Jobs recalled." The Atari experience helped shape Jobs's approach to business and design. I knew right then that I'd do it.ugg outlet storeCheapest Kids Ugg Boots These American made boots come in materials other than sheepskin.
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She came over one night, scared out of her wits, and he came over drunk, and my dad stood him down—saying "She's here, but you're not coming in.ugg outlet storeKINDELL'S DINNER WITH the Thurlows was not an entire success, for which there were more causes than one. "You might want to buy us for a few hundred thousand dollars," Jobs said when they got there. They hurt. I had never met anybody like that. [Ugg Australia Outlet Locations] The world was a very different place back then.
According to Deckers' brand-protection unit, in 2009 it took down 2,500 fake websites, 20,000 eBay listings and 150,000 other online auction listings with 60,000 pairs of counterfeit UGGs confiscated by customs agents. Ugg Boots Sale Cheap Ugg Boots " As a result, the family found itself financially strapped for a year or so while Steve was in elementary school. "There is something indefinable in an entrepreneur, and I saw that in Steve," he said. There was also the issue of his hygiene. [Ugg Boots Sale Cheap Ugg Boots] "We were at a public phone booth.
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Fans share thoughts on Lucas Matthysse-Viktor Postol, Adrien Broner-Khabib Allkhverdiev, Anthony Joshua, favorite fights, racial/stylistic double standards, mythical matchups and more in this week's Friday mailbag.read more
Keith Thurman: "You can doubt me as much as you want, but you are going to watch me throughout my career climb that ladder and reach the destination that I foresaw, and the one that I told you about, and that's Floyd 'Money' Mayweather."read more
There are some who have already asked Manny Pacquiao to retire and others who would do so if he loses to Brandon Rios on Nov. 23. Sugar Ray Leonard and George Foreman talk about how hard the decision to hang up the gloves can be.read more
IBF light heavyweight titleholder Bernard Hopkins has some options on what he does next but he says he's looking for a "super fight" for his next bout and would like to face Floyd Mayweather Jr. as a middleweight.read more
Curtis Stevens on Gennady Golovkin: "I'm coming there to wreck him. I'm coming to wreck the wrecking machine."read more
Hard-hitting light heavyweights Adonis Stevenson and Sergey Kovalev will face separate opponents on Nov. 30 in Canada, and Kovalev's promoter sees them facing each other down the road.read more
Trainer Abel Sanchez said Gennady Golovkin "is the best middleweight ever besides Sugar Ray Robinson and maybe Bernard Hopkins."read more
Donny Lalonde discusses his fateful catchweight bout with Sugar Ray Leonard in 1988 and how weight issues figured into the outcome, and offers his thoughts on the practice of inventing new weight limits for fights today.read more
Middleweight contender Matthew Macklin claims that he will handle unbeaten WBA titleholder Gennady Golovkin in similar fashion to how Bernard Hopkins knocked out then-undefeated Felix Trinindad in the 12th round.read more
Florida welterweight standouts Andre Berto and Keith Thurman are schedueld to fight in separate bouts on a Showtime-televised card in July. Berto will face veteran gatekeeper Jesus Soto-Karass; Thurman will fight fellow unbeaten puncher Diego Chaves.read more
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By Andrea Kay, Gannett
It's hard work to lie.
You have to keep track of your story and make sure details line up just right.
But people have good reasons for claiming to have worked in a job they never held. Or for telling colleagues, "Sorry, I've got to slip out of your meeting early to get to another one" — one that only exists in their lying mind. Or when a manager gives a job hunter hope: "You are just what we're looking for. We'll set up a meeting" — and never does.
Telling a lie to a boss, client, colleague or would-be manager or worker comes down to scoring points to advance your position or protect yourself, says Pamela Myer, author of the new book, Liespotting: Proven Techniques to Detect Deception.
Many of us encounter nearly 200 lies a day, according to studies. In a week you're mostly likely to hear a lie in 37% of phone calls, 27% of face-to-face meetings, 21% of IM chats and 14% of e-mails, she says.
It's disturbing, yet understandable how pervasive telling untruths is.
"Scientists have firmly established that lying is in fact one of the major building blocks of human social life," Myer says she discovered in her research. It appears to be hardwired into our brains.
Just as we have to trust to survive, we have to lie to survive, she says.
Every lie has a rationale. You may think it helps you feel less embarrassed, hold on to your job or get one you otherwise think you couldn't get.
You figure lying protects someone.
It helps to know that the majority are white lies. But white lies aren't the problem. It's the 10 or so "that were you to know the truth, would affect the decisions you make regarding your career, your business, your closest relationships and your personal life," Myer says.
So just as being deceptive can give you an advantage — if you get away with it — so does being adept at deception detection. In other words, get smart about reading people's expressions, timing, words and bodies.
You probably think you know a lie when you hear it. But people miss the lies they hear, not to mention lies they tell, Myer says.
If you want to be a better deception detector, you'll want to learn the nine clues to deceit, such as a fake smile that can be identified by lips and eyes.
It's also helpful to know the single most dangerous facial expression to watch out for in business: contempt. Keep your eyes out for a raised nostril combined with a curled upper lip.
Be on the alert for telltale phrases and responses that separate truth tellers from deceitful people. For example, distancing language is a hallmark of deceptive speech, Myer says. That's when someone tries to avoid referring to themselves in their lies, minimizes the value of something or impersonalizes another person.
For example, when someone is trying to deflect blame for a contentious relationship with a colleague, she may tell her boss: "You need to talk to that man about his attitude," Myer says.
To sound convincing, liars use bolstering statements like "To be honest," or "As far as I recall." Or they employ religious phrases like "I swear on a stack of Bibles the money was there when I left."
The challenge is to trust while staying alert for deception, Myer says.
And that makes me wonder. Were those two people who told me they didn't call back because they lost their cellphones in the woods this weekend spinning a wild yarn?
Career consultant Andrea Kay is the author of "Life's a Bitch and Then You Change Careers: 9 steps to get out of your funk and on to your future." Click here for an index of At Work columns. Send questions to her at 2692 Madison Road, #133, Cincinnati, Ohio 45208; www.andreakay.com or www.lifesabitchchangecareers.com. E-mail her at email@example.com.
Guidelines: You share in the USA TODAY community, so please keep your comments smart and civil. Don't attack other readers personally, and keep your language decent. Use the "Report Abuse" button to make a difference. Read more.


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I can be simple and complex, so stay simple we shall
I enjoy making things with my hands, anything from clothes, random arts and crafts to food and (maybe soon) alcohol. Anything DIY gets me super excited! I have this insatiable urge to know how and why everything works. So if you want to teach me how to make something please message me.
Thrift stores, flea markets and vintage shops are always a good time, I love finding a rare piece for dirt cheap, and modifying it.
I am charming, intuitive, and eclectic.
Trying to capture the human essence inside a mason jar
Remaining Balanced
Traveling the world, or just dreaming about it for now
Constantly learning and sharing = PHENOMENOLOGY
Actin a fool
Listening, like REALLY listening
That I am petite.
Slight Freckles
Waking Life, Inception, The Garden State, Eternal Sunshine, V for Vendetta, I ♥ HUCKABEES, The Life Acquatic, Crash, Closer, Little Miss Sunshine, Almost Famous, The Virgin Suicides, Confessions of a Dangerous Mind, American Beauty, 10 Things I hate about you, Anchorman, Clue, Hocus Pocus, Labrynth, The Goofy Movie
Grizzly Bear, Band of Horses, Fleet Foxes, Arcade Fire, The Postal Service, Beirut, Young the Giant, Bibio, Immortal Technique, Common, Lucero, Phoenix, Animal Collective, Sigur Ros, Royskopp, The Wallflowers, Camera Obscura, Rilo Kiley, Thievery Corporation, Karate, Modest Mouse, Brand New, Jimmy Eats World
Anything I can make. Lately I have been craving healthier foods (thank goodness) including lots of fruits and veggies. Other times I crave comfort foods, anything warm and cheesey :)
Mysteries, especially Agatha Christie or Ray Bradbury, and DIY books
Out for a twirl or a boogie shake
Dranking wine , Stitching and Bitching
Watching a show in marathon form via Netflix.


text: Different arrangements of atoms that can be converted into one another without the breaking of bonds are referred to as conformers or rotamers. Under ordinary conditions these conformers are not isolable intermediates as their energy differences are very small. The energy difference between the fully eclipsed and staggered isomers of ethane, for example, is of the order of 3 kcal mol-1, and at room temperature, these isomers are rapidly interconvertible. The difference between conformational isomers and configurational isomers is that the configurational isomers are stable, isomers species, while the conformational isomers are not.


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It´s a cruel blow to Tim Krul that he´s out for the rest of the season with a ruptured Anterior Cruciate Ligament Injury and Tim on his Twitter account revealed how devastated he was with the injury and that he had wanted to participate in Newcastle´s recovery this season.
A distressed Tim Krul leaving the field Saturday night
This is what Tim sent out after he heard the bad news from the scans that the ACL was indeed ruptured.
— Tim Krul (@TimKrul) October 11, 2015
There have been many messages of support coming for Tim, who has been at Newcastle for over ten years now and has so far played for us 176 times and has 8 full caps for the Netherlands. That included his heroics in the penalty shoot-out against Costa Rica in the World Cup last summer, when he was brought on just before extra time ended and brilliantly saved three penalties to get the Netherlands through to the semi-final.
All my support @TimKrul ! You'll come back stronger mate ! — Moussa Sissoko (@MoussaSissoko) October 12, 2015
@TimKrul just hear about you injured. Hope you get well soon. Be strong my friend. You r going to came back strong.
— Jonas Gutierrez (@elgalgojonas) October 11, 2015
You'll come back stronger, you've all my support as you supported me when I arrived to @NUFC Get well soon @TimKrul pic.twitter.com/lIwVxnNw6r — Ayoze Perez (@AyozePG) October 11, 2015
Sorry to hear the news @TimKrul hopefully we will be playing together again soon. pic.twitter.com/tGzIP0aMrT
— Paul Dummett (@PaulDummett) October 11, 2015
You come back stronger my friend ?? @TimKrul . pic.twitter.com/yQUY5eTOVh — Georginio Wijnaldum (@GWijnaldum) October 11, 2015


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Business, Management & MarketingFollow
|Management & Marketing
Bill Caskey and Bryan Neale: B2B sales trainers for the past twenty years share their strategies, frameworks, tips and tricks to help you leverage your talent, grow your skills and create your own sales success. You'll discover how you can shift your mindset, win with prospects and build long-term relationships with your clients so you can thrive and advance in your career. Bill and Bryan's approach to sales is funny, often quirky and always real. Their work has allowed them to help sales professionals, managers and leaders at hundreds of companies all over the world implement successful strategies and build profitable sales teams. Prospecting, sales communication, buyer resistance, proposals and RFPs, pricing, cold calling, sales forecasting, pain points, psychology, positioning, deal coaching, goal setting, leading and managing, achieving your goals and all the other things that work (and don't work) in the world of sales to help you be the best possible version of yourself.
August 1st, 2016
Episode 541 of 593 episodes
Calling all Sales Managers: there's an art to coaching your team after the ride along. In this episode, veteran sales trainers Bill Caskey and Bryan Neale talk to Sales Managers with tips (and things not to do) when coaching after a ride along experience. This episode isn't about the ride along itself— it's about what happens when you get back in the car. What makes a really good feedback session? How do you help your team grow from the experience? In today's episodeof The Advanced Selling Podcast, Bill and Bryan give you actionable tips to you can use on your next ride along. Hint: If you're not a Sales Manager, you probably should forward this episode to them after you listen. You'll be glad you did. ========================================= Want to have your sales question answered on The Advanced Selling Podcast? Email us [email protected] give us a call 317.575.0057 ext. 10. Looking for moresales training like this? Visitwww.advancedsellingpodcast.comfor access to exclusive listener sales tools and resources. Be sure to join the Advanced Selling Podcast LinkedIn Groupwww.advancedsellingpodcast.com/linkedin. =========================================
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Welcome to the Brain Training Podcast, the daily audio workout for your head. In this podcast we have two games for you, each with three rounds which get progressively harder. To enjoy the full experience, relax, and avoid distractions whilst you listen.


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Orexigen Data on Contrave Cannot be Trusted, Top FDA Official SaysMar 9, 2015
A top U.S. Food and Drug Administration official says data showing that Orexigen's obesity drug Contrave reduces the risk of heart attacks and cardiovascular death cannot be relied upon. Forbes reports that John Jenkins, director of the office of New Drugs, called the results "unreliable", "misleading" and "likely false". These findings caused shares of the company to jump up by 30 percent. In fact, if Orexigen does not rectify the situation it could face fines and civil penalties; Contrave could even be taken off the market.
Jenkins played a crucial role in the heart safety study of Contrave, Forbes reports. These trials are conducted to show that the drug does not increase cardiovascular events; the early data is supposed to be kept to a small, firewalled group of employees. "We required this study because we're concerned that Contrave may cause adverse cardiovascular events because of its effect on blood pressure and heart rate. So the likelihood that that drug is going to have an early benefit is highly unlikely. So people need to be very cautious about making medical decisions based on these data, and we're very concerned that investigators and patients may be unwilling to be in a trial based on these data when they are likely false readings of the actual effect of the drug." said Jenkins, according to Forbes.
Despite the fact that the findings reached a low p value (a statistical significance measure), Jenkins said "I think those are highly unreliable findings,"
"I am not a statistician, but I can tell you that Dr. Fleming, who is a statistician, and the statisticians at the agency, and other people who are expert in this area will tell you the only thing you can really conclude with confidence from this trial is that excess cardiovascular risk is not two or greater. You have a 95% confidence that the excess risk is not two or greater. You also have 95% confidence that the actual point estimate of the effect of this drug [on cardiovascular events] is somewhere below two. So the finding of .59 at the interim is highly unreliable independent of the p value." he said
Orexigen did not keep the data fire walled when it came to Contrave; FDA documents showed that over 100 people had access to the results. When the drug was approved, the FDA said a second study was needed. But now there are questions about whether this can be done due to data shown in a press release.
The agency noted two main problems with the Contrave heart trial. For one, the FDA said the data had leaked to too many people and that this could have changed the final result. Jenkins also said that far too many patients (over two-thirds) dropped off the study drug. However, the drop-outs stemmed from an FDA requirement in the trial; since the safety of Contrave was unknown, patients who were not losing weight were to be taken off treatment (or placebo). "The main reason we no longer have confidence in this trial to be the definitive answer to this question is the unblinding," says Jenkins.
Jenkins' main point is to not trust data Orexigen released about Contrave. "It points out the paradox of people rushing to believe the interim point estimate, because going into this trial all the priors were about cardiovascular harm. That shows the paradox of believing the interim analysis suggesting benefit."


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Result: Adam Peaty defends world titleGreat Britain's Adam Peaty defends his 100m breaststroke title at the World Championships in Budapest.
Phelps given SPOTY lifetime achievement awardBBC SPOTY contenders announcedMullen: 'Mixed emotions from Rio final'Susie Rodgers stunned by Paralympic goldKindred confirms Paralympic swansongResult: Rodgers continues GB swimming gold rushResult: Simmonds defends 200m title with recordResult: Record-breaking Kindred wins gold for GBAlice Tai devastated with Rio displayKane "really happy" with sixth-place finishGB add four Paralympic swimming medalsResult: Ollie Hynd takes freestyle swimming goldUSA swimmer Lochte banned for 10 monthsJazz Carlin 'can't wait' to compete again
Follow @sportsmole for the latest breaking news stories, and follow @sm_headlines to get every headline from Sports Mole
Result: Great Britain's Adam Peaty defends world title but fails to beat his own recordGreat Britain's Adam Peaty defends his 100m breaststroke title at the World Championships in Budapest.
Jul 24, 22:05
USA swimmer Ryan Lochte 'considered suicide' after Rio 2016 scandalSix-time Olympic gold medallist Ryan Lochte reveals that he was so low following his Rio 2016 controversy that he 'was about to hang up his entire life'.
Jun 6, 21:51
Michael Phelps given lifetime achievement award at BBC SPOTY showRecord-breaking swimmer Michael Phelps is given the lifetime achievement award at Sunday's BBC Sports Personality of the Year awards.
Dec 18, 21:38
BBC Sports Personality of the Year contenders announcedSixteen British competitors are in the running to be crowned as BBC's Sports Personality of the Year, including Andy Murray who has won the award twice in three years.
Nov 28, 21:22
Andy Mullen: 'Mixed emotions from Paralympic final'Great Britain's Andy Mullen admits that he has "mixed emotions" after swimming a personal best in the Paralympic 50m freestyle final, only to miss out on a medal.
Sep 13, 01:31
Susie Rodgers stunned by Paralympic goldGreat Britain's Susie Rodgers tells Sports Mole that she was more surprised than anyone by her gold medal-winning performance in the 50m butterfly at the Paralympic Games.
Sep 13, 01:20
Sascha Kindred: 'Gold is perfect way to end Paralympic career'Great Britain's Sascha Kindred tells Sports Mole that he will not be carrying on to Tokyo despite winning his seventh Paralympic gold medal in world-record fashion.
Sep 13, 01:02
Result: Susie Rodgers continues GB swimming gold rushSusie Rodgers picks up gold for ParalympicsGB in the women's 50m butterfly.
Sep 13, 00:17
Result: Ellie Simmonds defends 200m title with new world recordEllie Simmonds sets a new world record as she claims gold in the 200m individual medley.
Sep 12, 23:49
Result: Record-breaking Sascha Kindred wins gold for ParalympicsGBSascha Kindred sets a new world record on his way to 200m swimming gold at the Paralympics.
Sep 12, 23:38
Alice Tai devastated with performance in Paralympic 100m butterfly finalParalympicsGB swimmer Alice Tai tells Sports Mole that she is "really disappointed" with her seventh-place finish in the S10 100m butterfly final in Rio.
Sep 12, 23:23
Abby Kane "really happy" with sixth-place finish at ParalympicsGreat Britain swimmer Abby Kane tells Sports Mole that she is "really happy" with her sixth-place finish in the 400m freestyle final at the Paralympic Games in Rio.
Sep 12, 22:30
GB add four Paralympic swimming medalsGreat Britain pick up four more swimming medals on day two of action at the Paralympic Games in Rio de Janeiro.
Sep 10, 01:25
Result: Record-breaking Ollie Hynd takes freestyle swimming goldOllie Hynd breaks his own brother's world-record time to earn gold for Great Britain in the men's S8 400m freestyle at Rio 2016.
Sep 8, 22:57
USA swimmer Ryan Lochte banned from the sport for 10 monthsAmerican swimmer Ryan Lochte is banned from the sport for 10 months following his part in a controversial robbery claim while competing at Rio 2016
Sep 8, 16:14
Jazz Carlin 'can't wait' to compete againTeam GB swimmer Jazz Carlin admits that she is already thinking about returning to competition.
Aug 23, 17:17
United States swimmer Ryan Lochte apologises for false account of Rio 'robbery'American swimmer Ryan Lochte issues an apology on social media for giving a misleading account of a late-night incident at the Rio Olympics.
Aug 19, 16:22
Great Britain's Jack Burnell lashes out at Rio judges after open-water disqualificationGreat Britain's Jack Burnell slates the judges at the Olympic men's 10km open water race in Rio, saying that they "ruined the competition" after disqualifying him.
Aug 16, 15:55
Result: Michael Phelps bows out with 23rd Olympic goldMichael Phelps adds one final gold medal to his Olympic haul with victory in the 4x100m relay.
Aug 14, 03:14
Michael Phelps confirms retirementMichael Phelps insists that he is retiring after one last stab at Olympic gold in Rio de Janeiro.
Aug 13, 05:25


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Roosevelt High School cancels all extracurricular activities for Saturday because of snowstorm warming
March 15, 2013
According to school officials, Roosevelt High School in Johnstown has canceled all extracurricular activities for Saturday due to the winter storm and blizzard warning issued by the National Weather Service. Blowing snow is predicted throughout Saturday.
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- Greeley man convicted of kidnapping in 32-year-old rape case sentenced to 24 years in prison


text: 985 WGUS83 KLMK 142143 FLSLMK Flood Advisory National Weather Service Louisville KY 443 PM CDT FRI JUL 14 2017 KYC001-207-142345- /O.NEW.KLMK.FA.Y.0053.170714T2143Z-170714T2345Z/ /00000.N.ER.000000T0000Z.000000T0000Z.000000T0000Z.OO/ Russell KY-Adair KY- 443 PM CDT FRI JUL 14 2017 The National Weather Service in Louisville has issued a * Flood Advisory for Minor Flooding in Poor Drainage Areas for... North central Russell County in south central Kentucky... Northeastern Adair County in south central Kentucky... * Until 645 PM CDT * At 441 PM CDT, Doppler radar indicated heavy rain due to thunderstorms. This will cause minor flooding. Overflowing poor drainage areas will result in minor flooding in the advisory area. Radar estimates 1.5 to 2.5 inches of rain have already fallen. An additional inch of rain is possible over the next hour. * Some locations that will experience flooding include... Ella, Sycamore Flat and Webbs Cross Roads. PRECAUTIONARY/PREPAREDNESS ACTIONS... Turn around, don`t drown when encountering flooded roads. Most flood deaths occur in vehicles. A Flood Advisory means river or stream flows are elevated, or ponding of water in urban or other areas is occurring or is imminent. && LAT...LON 3711 8515 3719 8515 3719 8505 3715 8501 3711 8501 $$ EBW


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Disponible para visitas - Available for viewings
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Godwin Obaseki is the new governor of Edo State.
The All Progressives Congress (APC) governorship candidate was declared winner by the Independent National Electoral Commission (INEC) on Thursday, September 29.
According to INEC, Obaseki won in 13 local government areas and defeated Osagie Ize-Iyamu of the Peoples Democratic Party (PDP) who came second in the polls.
#EdoDecides: Godwin Obaseki wins Edo State Governorship Election.. http://bit.ly/2dGwmPv
Congrats to Godwin Obaseki as he is declared the next governor of Edo State. Those aggrieved should please head to a Tribunal.
The PDP has already rejected the results.
Details later
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This property is no longer available.Search for Available Property.
26 acres in Stone County, Missouri
CALL THE CRISPIN TEAM 417-335-3109. THE OFFICIAL BUYERS AGENTS.Amazing Opportunity at The Indian Ridge Resort Community in Branson West, MO.The chance of a lifetime, investment is located within minutes of the live music capital of the world, award winning golf courses, Big Cedar, Top of the Rock, the Branson Landing, Table Rock lake, Taneycomo Lake and Silver Dollar City! New price reflects 24 FINISHED units within 12 luxury townhomes, each unit will be approximately 1800 sqft and 500sqft garages. Also included are 67 building lots on 26 acres of land with views of the Ozark mountains and Table Rock Lake, 2 commercial acres on the highly desired Hwy 76, and a Billboard! Projected finish date of Fall 2015. Call today for a private showing! All measurements are approximate.
From Branson take hwy 76 West, past Indian Pointe Road, to left just after Stonebridge entrance.
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transcript :
Narrator : One peaceful morning, Tommy and his friends were going to Piggy's Pizza Palace.
Chuckie : Ooh, I wish I had Piggy or Ringo...
Tommy : Cheer up, Chuckie.
Angelica : Ooooh! A Cynthia Dream Car! I wish I could drive it.
Chuckie : Look! It's a big ball pit! Kimi and I played in it at daycare last week.
Angelica : Hooray! I got a thousand tickets!
Man : Dum-dee-dum.
Angelica : Huh? Hiiiiya! Whoa!
Another Man : Sorry, kid. You gotta stay here in the pig pen for ten minutes. Good-bye.
Angelica : But it's not my fault! ( sobs )
Tommy : Let's go before Angelica gets the car!
Phil and Lil : Okay!
Chuckie : Not me. Oh, I gotta be sick.
Angelica : ( goes out of the pig pen and drives the car ) Vroom! Vroom!
Man : Was that great? Thanks for Piggy and his barnyard friends! ( snorts )
Chuckie : AAAAAAAAAAAAAAAAAAAAAH!!!
Narrator : The end.


text:
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Abbey Oladapo
UpSkill Digital - Google
With over 7 years in the digital sphere he has empowered hundreds of SMEs to improve their presence online and grow through digital skills training. Prior to his current role, he championed Google products and services as the London market manager where he worked with technology partners like HP, Sony, Acer & Asus. During that period, he was also involved with the launch of the first Google stores globally. He studied International Business Economics at The University of the West of England and currently lives in London.


text:
Print advertisment created by Bohan, United States for Bohan, within the category: Agency Self-Promo.
Creative Directors: Dave Smith, Jon Arnold
Art Director: Josh Ford
Copywriter: Dave Smith
Photographer: Josh Ford
The Layout is very clean, the butterworth cut out in the middle messed with my reading at first, congrats on getting on AOTW
If you're going to delight your prospects with your textual flair, maybe invest in an apostrophe, or someone who knows where to use one. Apart from that clanger, there's the glaring layout caesura of the middle cut-out. But yes, congratulations on laying yourself bare on AOTW, and best of luck with what follows.
beautiful execution.
"If you are irritated by every rub, how will you be polished?"
— Rumi
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So we all know that god has given us the biggest gift that anyone can ever have for us. So we should respect them and love them from the bottom of our heart. But did anyone from you knows that why Christmas day is celebrated, If you know that then, it is good but if don't know that don't worry we will tell you about it in this article. So today, In this article we are going to share some Christmas Cartoon Photos which will include all the details about this day. So, guys, we hope you will surely like it. So guys get ready to have a look at it.
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Merry Christmas 2016 Cards Status Wishes & Images For Friends
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So you think you're sexy? How sexy are you? Take the How Sexy Are You quiz and find out exactly how sexy you are.A collection of categorized trivia games and quizzes. Includes rankings, community forums, an archive of useless facts, plus the ability to create and share trivia ...SoftSchools.com provides free math worksheets, free math games, grammar quizzes, free phonics worksheets, and games. Worksheets and games are organized by …Trivia games in a diverse range of subjects. Quizzes can be played interactively in unusual ways.An exciting exploration into your personality and iq, love tests, health test, quiz, quizzesSolve the clues and wind the words. New game every day.Watch the video above to check out Stephenie Meyer chatting with 'The Storytellers: New Voices of The Twilight Saga's' winning directors.BASIC SENTENCE PARTS. Identifying Sentence Parts (js) Sentence Parts: Basic (js) Body Parts: Quiz One (js) Body Parts: Quiz Two (js) Body Parts: Quiz Three (js)Preschool and Kindergarten *Preschool/Kindergarten* (numbers, colors, shapes, alphabet, animals) *Preschool Animals* (movies, create games, games, flashcards)Brain Teasers, Riddles, Trivia, Brain Exercises, Games, Forums and more... With over 20,000 brain teasers, riddles, logic problems, quizzes and mind puzzles submitted ...
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It is a 5km run - it's you against the clock.
Every Saturday at 8:00am.
The event takes place at Dargle Road, Lions River, Howick, 3265. See Course page for more details.
Nothing - it's free! but please register before your first run. Only ever register with parkrun once. Don't forget to bring a printed copy of your barcode (request a reminder). If you forget it, you won't get a time.
We all run for our own enjoyment. Please come along and join in whatever your pace!
It is entirely organised by volunteers - email firstname.lastname@example.com to help.
Every week we grab a post parkrun coffee at Piggly Wiggly - please come and join us!
Barbara BEYROOTI • Barry ECKSTEIN • Christina ECKSTEIN • Greg BEYROOTI • Limahl SOOKRAJ • Orrin COTTLE • Penny PURCHASE • Rosemarie NEVIN • Tarryn GIBSON
Piggly Wiggly parkrun takes place
every Saturday
at 8:00am


text:
Balance me rose otto wash
£1.00 (50p per 100ml)
This item is currently unavailable for ordering.
Product Summary
Gently soothing and softening protection. Beauty that works naturally. 99% natural. Lovingly made in the UK. No parabens, sulphates, petroleum, mineral oils, silicones, dea, pegs, propylene glycol, artificial fragrances and colours.'A gentle, soothing and softening award-winning body wash with skin-quenching and exquisitely fragranced rose otto, rose absolute and palma rosa essential oils, designed to naturally cleanse and protect even the most sensitive skin from dryness or irritation.'
Aqua, Sodium Cocoamphoacetate, Disodium Lauryl Sulfosuccinate, Cocamidopropyl Betaine, Lauryl Glucoside, Glyceryl Oleate, Coco Glucoside, Aloe Barbadensis (Aloe Vera) Leaf Extract***, Rosa Damascena (Rose Otto) Flower Oil*, Pelargonium Roseum Asperum (Rose Geranium) Flower Oil*, Citrus Aurantium Bergamia (Bergamot) Fruit Oil*, Cananga Odorata (Ylang Ylang) Flower Oil*, Pelargonium Roseum Asperum (Rose Geranium) Flower Oil*, Cymbopogon Martini (Palmarosa) Leaf Oil*, Salvia Sclarea (Clary Sage) Flower Oil*, Dehydroacetic Acid, Benzyl Alcohol, Citric Acid, Potassium Sorbate, Citronellol**, Geraniol**, Linalool**, Limonene**, Farnesol**, Benzyl Benzoate**, Benzyl Salicylate**, *Natural Pure Essential Oil, **Naturally occurring in Essential Oils, ***Certified Organic ingredient
Please note that while we take every care to make sure the product information displayed on our website is correct, product recipes are regularly changed. This may affect nutrition and allergen information therefore you should always check product labels and not rely solely on the information presented here.If you require specific advice on any Waitrose branded product, please contact our Customer Care Team. For all other products, please contact the manufacturer.This information is supplied for personal use only. It may not be reproduced in any way whatsoever without the prior consent of Waitrose Limited nor without due acknowledgement.


text:
This content has been marked as final. Show 2 replies
1. Re: Oracle resources not freeing upBilly~Verreynne Jan 9, 2013 5:23 AM (in response to 902998)Fix what?
You have not shown that anything specific is broken. You have not even shown which process is consuming that memory.
Also, why would 90% resource usage be better than 60% resource usage? Resources are there to be used. Resources not used, are wasted. The issue is effective usage.
You need to IDENTIFY what is consuming resources - before blindly blaming Oracle RAC as using resources ineffectively, and/or leaking resources.
2. Re: Oracle resources not freeing upkuljeet singh - Jan 9, 2013 5:56 AM (in response to 902998)
Each server had 16GB memory.Also check your PGA size.
MY SGA size on each node is 9GB.