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By Jordan Robertson, AP Technology Writer
SAN FRANCISCO A year ago, Advanced Micro Devices Inc. worsened its financial problems by botching the launch of a powerful new server chip. The flubbed introduction gave bigger rival Intel Corp. eight months to steal market share.
Now, Sunnyvale-based AMD is rolling out the successor to that chip months ahead of schedule in a bid to regain lost ground. AMD has about 20 percent of the global market for microprocessors, the brains of personal computers and servers, while Intel has the other 80 percent.
AMD's new Opteron processors are AMD's first chips based on 45-nanometer manufacturing technology. That means the company has shrunken the tiny parts of the circuits to an average of 45 nanometers wide, or 45 billionths of a meter. Smaller circuitry means the chips are cheaper to make and can hold more transistors, which boosts performance. AMD developed its manufacturing process in a partnership with IBM Corp.
AMD still lags Intel in that department, however. Intel has been selling its 45-nanometer chips for a year, an advantage that allowed Intel to maintain healthy profits despite pressure on the chips' selling prices and economic gloom.
The economic downturn has now hurt Intel badly, though. Intel chopped more than $1 billion from its fourth-quarter sales forecast Wednesday and lowered its profit guidance because slowing demand for PCs has hurt demand for its chips.
AMD also touts design tweaks in its new chips that the company says translate to 20 percent faster performance and 35 percent less power consumption when idle compared to the previous generation.
The new technology is especially important for AMD because the company is trying to climb back to profitability after losing $5.6 billion over the past eight quarters. It is also looking for ways to cut costs and is spinning off its factories in a joint venture with an investment arm of the Persian Gulf state of Abu Dhabi.
The company's first Opteron chip, released in 2003, allowed AMD to elbow its way into the lucrative market for server chips, an Intel stronghold. AMD lost ground, though, when Intel fired back with new chips. AMD pinned its hopes for a recovery on the launch of a new Opteron chip last fall, but technical glitches delayed the launch by eight months.
AMD is scheduled to tell financial analysts more about the new chip and the company's strategy at a conference at its headquarters Thursday.
Copyright 2008 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.
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Lee-Ann NiaziSalt Spring Island, British Columbia, CA
English (North American), English
Australian, British, French, German
Child, Middle Aged, Senior, Teen, Young Adult
Special Skills
Audiobooks, Cartoons, Educational
All of my experience comes from the nearly fifteen years I have spent as an educator, reading books aloud to my hundreds of students. I am extremely passionate about books whether reading them or writing them. I bring all of my characters alive with a passion and enthusiasm that is evident in every word.
Samson Q2U
Computer & Software
MacBook Pro / OS X Yosemite 10.5.5 / Audacity / Garage Band / Cakewalk Music Creator
Special Equipment
HP20 Playback headphones
Payment Terms
Hire Lee-Ann as a voice actor. Payment is made through Voices.com SurePay, an escrow service that guarantees your work is done to your satisfaction. Send payment securely by Visa, Mastercard or PayPal through Voices.com then download your files from the website.
Watch a video to see how to make a payment
Next Steps
To contact Lee-Ann Niazi about your project, request a quote today. We'll walk you through the process step-by-step. It's fast and easy.
This talent has not uploaded any demos yet.
Title of Your New Demo 7777 Listens
Hire Lee-Ann Niazi as a voice actor. Working with Lee-Ann Niazi is fast and easy. We'll walk you through the process step-by-step.
Request a quote for your project today.

subset: commoncrawl


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Midwest Pro Sound and Lighting is proud to bring you the best in DJ Equipment, including Turntables, Mixers, and CD/HD Players, as well as Lighting, PA's, Speakers, and DJ Equipment Cases. We carry a complete selection of Pro Sound Equipment for Stage and Studio, and all the Pro Lighting and Live Sound Gear you'll ever need for Club, Stage, and Arena setups.
And we're Chicago's top choice for PA/Sound System Rental, and Equipment Repair. In addition, our Synthesizer Demo Showroom lets you get your hands on the hottest synths available on the planet.
Come by and check it out! Chicago's best DJ Equipment / Pro Sound / Pro Lighting company brings its exceptional knowledge and customer service to the world via www.midwestprosoundandlighting.com. Check us last and you'll buy from us first!
Superbooth 2017 took place in Berlin during the weekend of April 20th-22nd …
This thing is great deal for people getting started out. $350 you get a …
The Toraiz AS-1 is a collaboration between Dave Smith and Pioneer and features …
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All prices are in USD.
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Famed action franchise Ratchet & Clank is back today, with a full remake of the original game for the PlayStation 4.
It's the debut of these cute critters on Sony's latest console and the early reviews are suggesting that it might just be the best game in the series, not to mention one of the finest examples of the genre currently available on the PS4.
The game is about a Lombax (basically a fox-cat looking thing) who is out to stop a baddie called Chairman Drek who wants to destroy other planets to make room for his own. He meets up with a very proper robot called Clank and gaming history is made.
For the re-imagining, the entire game has been remade with cutting edge graphics and features expanded parts of the story and levels, as well as elements from future games in the series. Here's the launch trailer.
If you're looking for something to play, or have a fondness for the series, this is a great way to get back up to speed with all things R&C, especially as there's an animated feature film on its way into cinemas soon.


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Selena Gomez is having a "pretty boring" birthday without Justin Bieber
This Friday, July 22, Selena Gomez will celebrate her 19th birthday. However, the star doesn't seem very excited to celebrate and claims the party will be "pretty boring."
Selena Gomez spoke to E! Online about her upcoming birthday: "I think my mom has planned something for me. I didn't really ask for anything, so I'm basically just going to be at tour rehearsal during the day."
"Maybe go to dinner at night with my family. Pretty boring… I actually think he'll (Bieber) be in Atlanta. But that's OK. We all gotta work," she added.
Also, despite crashing the wedding of another couple, Justin Bieber and his sweet Selena won't be together for her bday.
"I actually think he'll be in Atlanta. But that's OK. We all gotta work," the singer explained.
On a professional side, Selena is busy preparing her perfume, which will be released soon. She told reporters that she has worked on this project for almost a year and has overseen everything, from design to advertising.
"I've been working on my fragrance for almost a year now. I'm excited, [because] it's something I'm interested in… I'm already doing the whole process of smelling things and designing it and the campaign and everything, so it'll be fun," she said.
Her tour, Selena Gomez & The Scene North America Tour debuts July 24.


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I absolutely love this place. There are only two great hotels in the area, in my view. If I'm skiing, I might choose Four Seasons since it's ski in, ski out. But it is a zoo there and only a handful of rooms have views...More
Getting you more information on this room
Getting you more information on this room
"We were able to watch a young, stranded moose all day as he sought refuge from the heat under our porch."
"All rooms are the same layout half in reverse- check hotel website as they offer Grand Suites as well as..."


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Admire the most beautiful places of Mondaino and add them to your basket. YAMGU will create your trip considering distances, opening hours and weather.
Architectural scenario of Malatesta, which aims at the same time as content and container of museums, the paleontological museum, which since 1981 has housed in the ground floor rooms, allows you to make a long journey back in time to revisit the old marine natural scenery and living beings that during the Summit the Miocene (about 6 million years ago) characterized this portion of the Apennines along the valleys of the leaf and the Laver. It is rich paleontological heritage, formed mainly from fish-fossils belonging to over twenty different species – remnants of leaves (filliti) and examples


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Glambrey 5-Piece High Dining Set
94 cm H x 112 cm D
Measurements37" H x 44" D
94 cm H x 112 cm D
90 lbs
40.8 kg
- Tempered glass insert
- Welded tubular metal frame
- Stools upholstered in polyester
- Maximum number of chairs 4
- Cherry veneer pattern
- Open display space on base
- Rope twist accents
- Brown
- Tempered glass
- Hardwoods
- Polyester
- Metal
- Cherry veneers
Infuse your home with a transitional style with the addition of this high dining set. The woodwork in the Glambrey, has a beautiful warm brown finish that contrasts nicely with the rusty bronze finished metal. The table top features a tempered glass insert and a rope twist detail on the edge. The seats of the stools are upholstered for extra comfort. The scrolling pattern of the metal details give this set a unique look that will make a statement in your dining room
On Display at Your Local Store
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House For Sale in Calgary, AB - 3 bed, 2.5 bath (176 Silverado Range Close SW) - $450,000
Seller Verified ListingSeller Verified ForSaleByOwner.ca web site postings have been posted by sellers who have used a valid credit card when creating their listing, giving our buyers more confidence in the listings presented on this web site.
A Seller Verified listing shows buyers that the seller is serious about selling their property, and that they are a legitimate seller - a very important element when using the internet to sell a large ticket item like a home.
Motivated Owner
Main Features
- Bedrooms: 3
- Bathrooms: 2.5
- Square Footage: 1,728
- Lot Size: 3692 sq ft
- Stories: 2 Stories
- Parking: Attached Garage
- Year Built: 2006
- Annual Taxes: $2,763
The Basics
- Price: $450,000
- Property Type: House / Detached House
- Ad Type: For Sale
- Listing ID: 131591
- Last Updated: 2017-07-20
- Address: 176 Silverado Range Close SW
- City: Calgary
- City Quadrant: South West
- Province/State: Alberta
- Postal/ZIP Code: T2X 0C1
- Country: Canada
Extra Features
To send an email to the seller, please fill out the form below.
Property Description
***I'm offering a cash back to buyers who contact/purchase through me directly. I'd rather pay you than your realtor. This can be used for new furniture, maybe a down payment on a car? No strings attached, do with it whatever you like. It will be available upon possession.***
This home is located on a "no through traffic" street. There are many upgrades including hardwood flooring throughout most of the house, wainscoting, main floor laundry, granite and maple cabinets in the kitchen, an oversized dining area, and large deck in the back yard.
The basement is unfinished but has been set up and used as a shop. Perfect for the craftsman or hobbyinst. It wouldn't take much to make the area into a play area or use it simply for storage.
The bonus room is HUGE with a vaulted ceiling. Ideal for a home theater or a dream come true for the gamer in the house.
The master bedroom hosts a walk in closet and ensuite with jacuzzi tub. If you're looking for storage, this room has it. An Ikea wardrobe is installed and easily customized to suit your needs.
Silverado hosts its own shopping area including Sobey's Grocery/Liquor, a gym, medical clinic, vet clinic, Shopper's, etc. Pretty much everything you need for day to day in there. Gorgeous walking/bike paths and playgrounds as well as a soccer field with baseball diamonds. If you need the big box stores like Walmart and Home Depot simply cross 22x to the north and that is all there including a huge C-Train station.The location of this neighbourhood is amazing. Super quiet small town feeling with all the city amenities.
Buyer Agent Friendly
This seller is willing to negotiate commission with any real estate agent who brings an acceptable offer from a qualified buyer.
Room Dimensions
|Main Level
|Dining Room
3.91 m x 3.18 m
(12'10" x 10'5")
|Main Level
3.00 m x 2.84 m
(9'10" x 9'4")
|Main Level
|Living / Dining Room (Combined)
4.85 m x 3.94 m
(15'11" x 12'11")
|Second Level
|Master Bedroom
4.14 m x 3.66 m
(13'7" x 12')
|Second Level
|Bedroom 2
3.63 m x 2.72 m
(11'11" x 8'11")
|Second Level
|Bedroom 3
3.28 m x 2.57 m
(10'9" x 8'5")
|Second Level
|Bonus Room
5.16 m x 4.70 m
(16'11" x 15'5")
Approximate Map Location*
* Each seller is responsible for ensuring that their map location is accurate. Please contact the seller directly if you have any questions.
This property for sale has been tagged by the seller as close to Black Diamond, Bragg Creek, Camrose, Chestermere, High Prairie, Okotoks, Alberta.
Featured Services
Mortgage & Financing
Canada-Wide (excl. Québec)
Photo, Video & Virtual Tours
British Columbia
Home Builders & Developers
British Columbia


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Getting Focus: Methods and Techniques I Use
I often find that I have trouble staying focused. Focus is a challenge for anyone, but it can get especially troublesome for creative minds. Your brain desires stimulation constantly, otherwise you find yourself sidetracked. You'll procrastinate, fail to complete tasks and as time passes you lose all efficiency. In this article, I'd like to introduce you to a number of things that have helped me to maintain focus on a daily, weekly or monthly basis.Read More


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Minecraft: The Dungeon Update is a major update for Minecraft, and it is known as 1.12. This update is based on a brand new dungeon for the Nether, but also features brand new items, blocks, and mobs. This update is being made by TheFireDragoon with permission from LegendaryIce for it to be after The Pushy Update.
- Netherite Ore - Found only in Nether Dungeons, Netherite Ore has to be smelted in a Nether Furnace to become ingots - otherwise it just becomes Netherite. The player is required to get as much Netherite Ore as they can so they can prepare for the Nether Dungeon's boss.
- Netherite Block - Crafted with 9 pieces of Netherite, Netherite Blocks have no purpose. They can be put in a crafting table to turn back to the Netherite.
- Netherite Stairs - Crafted with Netherite in the shape of stairs, Netherite Stairs can be walked up and walked down.
- Netherite Door - Crafted with Netherite in the shape of a door, Netherite Doors can be opened to walk through.
- Nether Trapdoor - Found only at the entrances of the Nether Dungeons, Nether Trapdoors cannot be mined and require a Nether Key to open it.
- Nether Furnace - Crafted with Netherite in the shape of a furnace.
- Ghost - A transparent monster, Ghosts only appear in Ghost Campsites and Ghostlands. Once they spot a player, they will never stop chasing them. They have 16 Hearts, and can drop any kind of wooden or stone tool. They can also drop torches.
- Ghost Campsite - Ghost Campsites are haunted Campsites, inhabited by Ghosts. You can find no Bear Traps in Ghost Campsites, and it's possible to find Ghost Blocks in these Campsites.
- Nether Dungeon - Nether Dungeons are the main focus of the update. To enter, you'll have to find a trapdoor usually near lava. You'll have to use a Nether Key to actually unlock the trapdoor. Once you open it, you can enter the Nether Dungeon. It is made out of various materials, including Nether Bricks. There can only be three Nether Dungeons in the entire Nether. Each one features brand new mobs, exclusive loot, a boss, and amazing rewards.
- Ghostlands - Ghostlands look like Mushroom Islands, but they are infact not. Once you enter one of th Ghostlands, you get Blindness. Ghosts can be found in Ghostlands, and Monsters spawn more often here. It is extremely rare to find any sort of animal in the Ghostlands. Besides that, you still can find Giant Mushrooms and the ground is the same.
- Bandage - Crafted with , when right clicked with Bandages will heal you by one heart as well as cure Bleeding. They can take three uses before not working.
- Netherite - Acquired by smelting Netherite Ore in a normal furnace, Netherite is only used for Netherite Blocks, Netherite Stairs, Netherite Doors, and a Nether Furnace.
- Netherite Ingot - Acquired by smelting Netherite Ore in a Nether Furnace, Netherite Ingots can create Netherite Armor and Netherite Tools.
- Netherite Tools - Netherite Tools include the Netherite Hoe, Netherite Pickaxe, Netherite Shovel, Netherite Sword, and Netherite Axe. Instead of using sticks to craft Netherite Tools, you have to use Emeralds.
- Blindness Potion - Causes Blindness. Can be transformed into a lingering potion and splash potion. Brewed with .
- Saturation Potion - Causes Blindness. Can be transformed into a lingering potion and splash potion. Brewed with .
- Stone Armor - Stone Armor gives the same defense as Chainmail Armor, and essentially replaces it. It is crafted with Stone, instead of Cobblestone.
- Netherite Armor - Netherite Armor gives five more defense than Diamond Armor, making the total defense 25. It is crafted with Netherite Ingots.
- There is now a new section of items in creative called Traps.
- Bear Traps - Found in Campsites, they freeze the player/mobs for 3 seconds while dealing damage. They have a small chance to inflict Bleeding.
- Lava Trap - Rarely found in Caves, a Lava Trap takes the form of Water but is actually Lava. While in your inventory, it looks like a bucket of water.
- Spawner Trap - Rarely found in Dungeons, a Spawner Trap looks just like a Monster Spawner - but instead of it spawning Monsters, it'll explode once you go near it. It will not work until it has been in the world for atleast a minute. While in our inventory, it looks like a monster spawner.
- Ghost Block - Crafted with any kind of block and one Invisibility Potion, a Ghost Block looks just like the Block, except you can walk through it. You can put any amount of the kind of block when crafting it to get that amount. They can also be found in Ghost Campsites.
Potion Effects
- Bleeding - Inflicted by Swords (10%) and Bear Traps (35%), they cause the mob or player to slowly lose health for a random amount of time (1-20 seconds.) Bleeding can be stopped automatically by using a Bandage.
- You can deactivate and reactivate Monster Spawners using redstone.
- Blindness can now be inflicted by Blindness Potions.
- Saturation can be inflicted by Cake and Saturation Potions.
- Campsites have a chance to be Ghost Campsites.
- If you use that armor set's weapon while wearing the full set, it will deal one more heart of damage.
Bug Fixes
- It is no longer possible to push & pull Barriers, Tripwire, Redstone Dust, and several other blocks that should not be pushable or pullable.


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If you like shopping around the Apple company App Store or in the iTunes Store, you can expect to undoubtedly really like receiving an iTunes present credit card as a provide. And even though you don't obtain this object as a gift item, there are various online shops where you can get this distinct form of electronic cards effortlessly. In addition there are diverse transaction approaches and quantities or denominations for you choose to from so you can buy the best one who fits your finances and demands. 直播平台充值
After you get your iTunes gift greeting card, you are able to surely store for your heart's information. You are able to obtain every one of the applications, tunes or albums, Tv programs, and films you desire in your Apple device. You are going to easily be inclined to max out this credit card on each one of these items. However, you can nonetheless stretch the application of or volume packed inside your iTunes present card. How? Comply with the following:
The applications tunes or
- Select the totally free things initially. If you truly want to stretch out.
- If you love purchasing on the Apple company Iphone app Retailer or on the iTunes Retailer, you may.
- After you get the iTunes gift item cards, you can certainly shop to the heart's.
- Acquire inexpensive or reduced iTunes gift cards. You will undoubtedly spend less and acquire the most from.
Acquire affordable or reduced iTunes gift certificates. You are going to undoubtedly cut costs and get the most out of your iTunes present credit card if you buy the one that will come in a marked down amount. This is especially helpful if you intend on paying a great deal on iTunes or perhaps the Iphone app Retail store. Find out which online stores or distributor sell iTunes gift certificates cheaper than the actual face benefit. In addition there are some web sites that acquire this particular electrical credit card from people who don't desire them and re-sell these people to buyers for the low cost.
Select the free goods very first. If you really want to stretch the investing potential of your respective iTunes gift idea card, locate and down load every one of the freebies initial. You can acquire the majority of the most in-demand software anyway for example games, fundamental business office-related ones, along with the apps you should use for editing and enhancing and sharing photographs. You may also use the Top rated Free of charge chart inside the Application Store to find out which game titles and apps may be delivered electronically for free. Additionally, there are blogs and websites which share info on which tracks are accessible for actually absolutely nothing on iTunes.
Games fundamental business
- Choose the free of charge goods initial. If you want to extend the spending potential of your iTunes.
- When you get the iTunes gift.
- Buy cost-effective or marked down iTunes gift certificates. You are going to.
- If you like purchasing around the Apple company Application.


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When you remember that Ayoze Perez was signed last year for the Development squad summer when we beat some big clubs to sign him from Tenerife for €2M – he will not be getting anywhere near big wages on Tyneside.
Yet he produced immediately for us last season with seven good goals in 39 appearances including the goal of the season at West Brom and this season he has three goals in 12 appearances for us and continues to improve.
Ayoze Perez – Newcastle are number one
His improvement is such that big clubs like Manchester United, Tottenham and Arsenal are said to be interested in signing him in January.
We have reported a few times this season that Newcastle need to give Perez a new deal and quickly in order to help keep him at the club.
And there is good news in the Chronicle today that Newcastle are planning to do just that – so we hope it's before January when some offers are likely to come in for the impressive 22 year-old striker.
Tottenham tried to get him on the last day of the summer transfer window with the news that Newcastle turned down an offer as big as £15M for him – but we doubt it was really that big.
However, the good news is that Ayoze seems to just love it at Newcastle, so an improved five-year deal for the youngster is surely on the cards before the end of this year.
That will help Newcastle keep the striker not only in January but in the summer too.
And if we are to build a team that can win something in the (very) near future – we will have to keep stars like Ayoze at the club.
Here's the great Perez goal at West Brom including the impressive build up play from Newcastle.
Comments welcome.


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Nerd Court is the work of creator Gary Whitta (The Book of Eli, The Walking Dead) and director Adam Stein. It's like Judge Judy for nerds. This time Jonathan Frakes is forced to take the stand in his own, uh, Riker's defense to help decide if the character was really all that or totally overrated.
Tina Huang, a longtime TNG fan takes the anti-Riker side while Commander Holly from Syfy's Heroes of Cosplay takes the pro-Riker side. Watch the video after the break and see which side wins out.
(via Nerdist)


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The expression of FOS, a gene critical for monocyte and macrophage function, can be inhibited by statins through the disruption of a cholesterol independent signaling pathway. In this pilot study, we hypothesized that blood FOS mRNA levels will be sensitive to statin treatment independent of LDL cholesterol levels.
Three cohorts at increased risk of or with cardiovascular disease (CVD) were studied. Blood FOS mRNA levels were measured before and after statin treatment or in patients under stable treatment.
Statin treatment for three months significantly reduced blood FOS mRNA and LDL cholesterol levels. However, in subjects with similar LDL levels achieved by different doses of long term statin treatment, there was an inverse relationship between statin dose and FOS expression.
FOS mRNA levels appear to be a sensitive marker of statin treatment that is dissociated from cholesterol levels.
Statins have been proposed to exert pleiotropic benefits that extend beyond that predicted by cholesterol reduction (1,2), even though some analyses argue against the existence of such non-cholesterol related effects in preventing adverse cardiovascular events (3). A meta-regression analysis of data from statin and non-statin clinical treatment trials has shown that the changes in LDL cholesterol levels alone are sufficient to account for the decrease in cardiovascular events (3). However, at the cellular level, statins have potent anti-inflammatory and other beneficial effects on immune, endothelial and smooth muscle cells (2). At the molecular level, these HMG CoA reductase inhibitors not only decrease cholesterol synthesis but also inhibit the isoprenylation and activation of important intracellular signaling proteins such as RhoA and Ras that can affect pathogenesis (1,2). These disparate basic and clinical observations indicate a need for further translational investigations to improve our understanding of statin treatment effects. In this regard, the identification of biomarkers that provide additional information about the therapeutic activities of statins may be helpful.
Various cellular elements and signaling pathways contribute to atherosclerosis, but circulating inflammatory cells play a pivotal role in the initiation and final manifestation of disease (4,5). Recent work examining the transcriptional profiles of blood cells in patients with coronary artery disease provide insights into cardiovascular pathogenesis supporting the potential clinical utility of such investigations (6-8). We previously reported that the mononuclear cell mRNA level of the Finkel-Biskis-Jinkins Osteosarcoma (FOS) gene, a transcription factor essential for monocyte differentiation into macrophages (9), was correlated with the severity of atherosclerosis (10). The localization of FOS to macrophages and smooth muscle cells in plaques and its importance in calcification suggest that it may also play a direct role in atherosclerosis (10-12). Based on the known transcriptional regulation of FOS through a cholesterol-independent pathway (13), we hypothesized that blood FOS levels will be sensitive to statin treatment independent of LDL cholesterol levels and in a dose dependent manner. The following translational study was designed to determine whether FOS expression in blood can serve as a statin treatment response marker that could then be evaluated further with regard to clinical application given, for example, the questions about the pleiotropic effects of statins.
In accordance with the guidelines of the National Institutes of Health and Emory University Institutional Review Board committees, subjects were enrolled into three separate clinical studies between 2005 and 2009.
Nine subjects at increased risk for cardiovascular disease (CVD) either with known diabetes or with at least three components of the metabolic syndrome were enrolled at Emory University School of Medicine (Supplementary Table 1). Blood samples were obtained at baseline and after 3 months of treatment at a 10 mg/day atorvastatin-equivalent dose by their LDL cholesterol lowering potency (5 subjects, atorvastatin 10 mg/day; 4 subjects, pravastatin 80 mg/day) (14).
46 patients were enrolled in this cross-sectional study examining the effect of statin dose on mononuclear cell FOS expression. Most of these patients had known coronary artery disease and were being treated long term with various doses of statins to target LDL levels according to clinical guidelines (LDL < 100 mg/dL) at the time of the study (Supplementary Table 2) (14). Because of the small number of subjects on higher statin doses, subjects were pooled together into one "high dose" group (40-80 mg atorvastatin equivalent/day: 40 mg, n=7; 60 mg, n=1; 80 mg, n=6) and one "low dose" group (10-20 mg atorvastatin equivalent/day: 10 mg, n=15; 20 mg, n=17). Within this cross-sectional cohort, 78% of the patients (36 out of 46) were on atorvastatin and the remainder were on various other statins which were converted to atorvastatin equivalents (14). The clinical characteristics of the low and high statin dose groups were not significantly different (Supplemenary Table 2).
For examining FOS expression in whole blood, samples collected in PAXgene tubes from 32 subjects enrolled in the ClinSeq™ Project (15), a whole-genome sequencing NHGRI-NIH study initially targeting cardiovascular diseases, were obtained and analyzed. These subjects at high risk for coronary artery disease or with known disease were on long term statin treatment and their clinical characteristics were not significantly different (Supplementary Table 3). They were also pooled into a "low dose" group (10-20 mg atorvastatin equivalent dose/day: 10 mg, n = 7; 20 mg, n = 12) and a "high dose" group (40-80 mg atorvastatin equivalent dose/day: 40 mg, n = 4; 60 mg, n = 3; 80 mg, n = 6). In this cohort, 56% of the patients (18 out of 32) were on atorvastatin and the remainder were on various other statins.
To purify mononuclear cells, blood samples were drawn into citrate-containing Vacutainer CPT tubes (Becton Dickinson), density gradient centrifuged, and frozen within 2 h for subsequent RNA purification (10). To obtain RNA from whole blood, the samples were drawn into PAXgene Blood RNA tubes (PreAnalytiX) and also frozen within 2 h prior to RNA purification. Although PAXgene blood samples have stable RNA levels up to at least 6 months at −20 °C according to manufacturer's data, we stored all our samples at −80 °C to ensure longer term stability. Furthermore, mononuclear cells stored in RNA lysis buffer at −80 °C have continued to retain stable FOS expression levels over the course of years in tested samples. FOS mRNA levels were measured by real-time reverse transcriptase polymerase chain reaction (RT-PCR) and normalized to an internal control gene as previously described (10). Serum hs-CRP levels were determined by immunophelometry using the Siemens/Dade Behring or IMMAGE CRPH (Beckman Coulter) assay.
Statistical analyses were performed using GraphPad Instat (version 3.06) and Prism (version 4.00). Wilcoxon matched-pairs signed ranks test was used to compare variables before and after statin treatment in the prospective study group, and the Mann-Whitney test was used to analyze continuous variables between the different statin dose groups. The Fisher exact test was used to compare categorical variables. The Spearman's rank correlation test was used to analyze for the linear relationship between FOS and LDL or hsCRP levels in each subject. p values were calculated by two-tailed tests and considered statistically significant if p<0.05.
We first investigated whether statin treatment prospectively lowers FOS levels in subjects with diabetes or components of the metabolic syndrome at high risk for CVD (Supplementary Table 1). Circulating mononuclear cells were obtained at baseline and after three months of treatment. After statin therapy the median LDL cholesterol level decreased from 169 mg/dL [interquartile range (IQR) 144 to 184] to 112 mg/dL [IQR 98 to 124] and the mean value decreased by 33% (p=0.004, Fig. 1A). The median mononuclear cell FOS mRNA level decreased from 0.76 [IQR 0.38 to 1.7] to 0.50 [IQR 0.28 to 0.73] and the mean value decreased by 44% (p=0.03, Fig. 1B). Importantly, there was no significant correlation between the relative decreases in LDL cholesterol and FOS mRNA levels, demonstrating their differential responses to statin treatment (Spearman correlation coefficient= −0.2, p=0.7). Furthermore, hsCRP levels were not significantly affected by statin treatment during the time course of this study (pre-treatment median 5.1 [IQR 2.2 to 11] versus post-treatment median 6.3 [IQR 4.4 to 8.6], p=0.7, Fig. 1C).
We next examined the relationship of statin dose to FOS mRNA levels. In this cohort of patients at high risk or with known coronary artery disease, the cardiovascular risk factor profiles were similar for the low and high statin dose groups (Supplementary Table 2). The mean LDL cholesterol levels were also similar for the two groups indicating that they had been successfully titrated to target levels according to clinical guidelines (p=0.5). In contrast, we observed an inverse relationship between atorvastatin equivalent dose and the median mononuclear cell FOS level in the high (0.16 [IQR 0.08 to 0.39]) versus low (0.36 [IQR 0.18 to 0.91]) statin dose group (p=0.03, Figure 2A). In further support of their independent modulation, there was no significant linear relationship between FOS mRNA and LDL cholesterol levels in the individual subjects (Spearman r= −0.09, p=0.5). Again, as in our prospective statin treatment study, the inflammatory marker hsCRP levels were not significantly different by statin dose in this cross-sectional cohort of subjects (Supplementary Table 2).
Because special blood sample handling and processing requirements can hinder the performance of large-scale clinical studies, we tried to replicate our findings in an independent population of patients using a simplified collection technique. To achieve this, we examined FOS expression in whole blood samples collected from subjects in the NHGRI-NIH ClinSeq™ Project (15) at high risk for coronary artery disease or with known disease (Supplementary Table 3). In these subjects who were being treated with statins to similar target LDL cholesterol levels, we again observed a significantly lower median FOS mRNA level in the higher dose statin treatment group (0.54 [IQR 0.29 to 0.68]) compared to the lower dose group (0.70 [IQR 0.48 to 1.24]) (p=0.04, Fig. 2B), a pattern that was not evident for LDL cholesterol or hsCRP (Supplementary Table 3). There was also no significant correlation between FOS mRNA and LDL cholesterol levels in the individual subjects from this cohort (Spearman r=0.2, p=0.2).
Using samples obtained from patients in three different clinical studies, we have demonstrated that FOS mRNA levels in blood are reduced by statin therapy and that the reduction is reflective of statin dose. Furthermore, the inhibition of FOS expression by statin appears to be dissociated from its effects on LDL cholesterol and hsCRP. This observation is consistent with the known molecular mechanism by which non-cholesterol related pathways can modulate FOS expression (1,13). In summary, our current observations provide support for the idea that FOS, a transcription factor that responds to and integrates multiple signaling pathways, could serve as an in vivo readout of statin treatment response independent of LDL cholesterol.
There are some limitations to this study. It was not designed to determine the prognostic significance of FOS levels but, rather, to determine whether FOS levels in blood can serve as a marker of statin treatment independent of LDL cholesterol levels. Although our current study provides proof of concept, it will be important to further characterize our findings in a larger prospective treatment study using different doses and types of statins and to determine its clinical significance. In addition, it may be useful to serially examine both the mononuclear cell and whole blood levels of FOS in the same subjects. In the cross-sectional studies (Studies 2 and 3), we do not have the pre-statin treatment LDL cholesterol or hsCRP measurements, therefore, we cannot conclude whether the degree of reduction compared to their baseline levels correlate with FOS reduction. However, in our prospective statin treatment group (Study 1), there was no significant correlation between the reductions in LDL or hsCRP and FOS levels.
The demonstrated sensitivity of FOS to high dose statin using a simplified method of blood collection as with the ClinSeq™ Project samples shows the feasibility of conducting larger scale prospective studies or retrospective investigations of stored samples. Increased interest in genetic biomarkers has resulted in larger numbers of clinical studies storing whole blood samples for gene expression analysis (15), thus retrospective analysis of such samples from large statin treatment clinical trials, for example, may be useful in the future. Another possible application of measuring FOS levels may be for monitoring treatment compliance which is known to significantly impact the outcome of various patient populations with heart disease. This may be especially useful in patients whose pretreatment cholesterol levels may be low or in those whose cholesterol levels are relatively unresponsive to statins. It is tempting to speculate that the measurement of new biomarkers such as FOS may provide additional insights into the biology of cardiovascular diseases to improve treatment outcome.
The authors wish to thank Drs. Ping-yuan Wang, Myron A. Waclawiw, Michael Sack and Toren Finkel for helpful discussions. We also thank Amy Linn, Danielle Singer, Paul Gobourne and Laurel Mendelsohn and Dr. George Csako for sample and data collection. This research was supported by the Intramural Research Program of the NHLBI and NHGRI, NIH, and the National Center for Research Resources (NCRR) Grant M01-RR00039 for the Emory General Clinical Research Center (GCRC).
Dr. Quyyumi has received research funding from Pfizer, which manufactures atorvastatin, a product related to the research described in this paper and has received honoraria as a consultant. The terms of this arrangement have been reviewed and approved by Emory University in accordance with its conflict of interest policies.
Publisher's Disclaimer: This is a PDF file of an unedited manuscript that has been accepted for publication. As a service to our customers we are providing this early version of the manuscript. The manuscript will undergo copyediting, typesetting, and review of the resulting proof before it is published in its final citable form. Please note that during the production process errors may be discovered which could affect the content, and all legal disclaimers that apply to the journal pertain.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


text:
GraphicRiver Abstract vector shiny background design 3019001
Stock Vector \ Decorative \ Backgrounds
Design \ Background \ Wallpaper \ Motive \ Patter \ WhiteAbstract \ Illustration
Stock Vector - Abstract vector shiny background design 3019001 by articular @ GraphicRiver
Stock Vector \ Decorative \ Backgrounds
Abstract vector shiny background design. EPS 10 illustration.
Layered: Yes; Graphics Files Included: JPG Image, Vector EPS, AI Illustrator; Minimum Adobe CS Version: CS.
Keywords: art, backdrop, background, banner, blue, bright, composition, concept, decoration, decorative, design, digital, dynamic, effect, elegance, elements, eps10, flare, glare, graphic, grunge, image, light, motive, patter, ray, space, style, wallpaper, white.


text: tedcruz.org [ Texas Election Wrap-Up By John Williams August 1, 2012 Ted Cruz breezed to a run-off election victory over Texas Lt. Governor David Dewhurst. Read More Category: News, Political News, Texarkana News Tags: KKYRFM, Texas Elections Send to a friend! Share on Facebook Share on Twitter Pin it! Reddit This! Share on Tumblr!


text:
Support For Heavy Cake Separators
Decorating By mlwideman Updated 15 Aug 2012 , 10:53pm by kakeladi
I hope I can get some suggestions to pull off a cake I have for this weekend. I am using a mirrored glass and champagne flute design for the cake separator. The bottom tier is 14", the middle tier is 10" and the mirrored glass and champagne flute design will be on top of the 10". There will be a 6" cake on top. For those of you who have used heavy separators or toppers, what would you suggest? The separator is 2 lb. and 4 oz. I know plastic hollow dowels are probably the best option. Any suggestions are greatly appreciated.
How did you get on please Melanie? I fancy trying something similar with martini glasses and mirrors (though I thought acrylic mirror might be better if rigid enough) but worried about weight too.
Helen.....The use of Wiltonn's hollow, plastic dowels should to nicely.
Just be sure you cut *all* of them exactly the same length so everything will be level
Quote by @%username% on %date%


text:
|Message view
|« Date » · « Thread »
|« Date » · « Thread »
|"Aigner, Thomas" <TAig...@WescoDist.com>
|Reading Performance
|Thu, 07 Dec 2006 18:14:46 GMT
Howdy all, I have a question on reading many documents and time to do this. I have a loop on the hits object reading a record, then writing it to a file. When there is only 1 user on the Index Searcher, this process to read say 100,000 takes around 3 seconds. This is slow, but can be acceptable. When a few more users do searchers, this time to just read from the hits object becomes well over 10 seconds, sometimes even 30+ seconds. Is there a better way to read through and do something with the hits information? And yes, I have to read all of them to do this particular task. for (int i = 0;(i <= hits.length() - 1); i++) { if (fw == null) { fw = new BufferedWriter( new FileWriter( searchWriteSpec ), 8196) ; } //Write Out records String tmpHold = ""; tmpHold = hits.doc(i).get("somefield1") + hits.doc(i).get("somefield2"); fw.write(tmpHold + "\n" ); } Any ideas on how to speed this up especially with multiple users? Each user gets their own class which has the above code in it. Thanks, Tom
|View raw message


text: CANDICE made my ovaries explode on that 2nd song and a girl never does that to me. WOW. Is it just me or does Angie look like Miley Cyrus? The only thing about Candice is, after Idol, who will be buying her records? Will radio play her music? Lazaro, LOL. Im not feeling Janelle. Country is not my thing, but Kree does have a good voice. Amber is cute, but judges overrated her tonight, IMO. Shes a bit pitchy especially her 2nd song.


text:
nelsonmanl... Photographer
Gloria GohModel Female Singapore, Singapore, Singapore
Mayhem # 3481734
About MeI am still pursuing a modeling career because this has been a dream of mine since I was a child. I'm motivated, very friendly, outgoing person and generally a fun person to work with. I'm easy to work with and I'm very punctual and take my job very serious for every assignment. I was mainly involved in events previously and would like to try photoshoots to build up my modelling portfolio. Sorry if some of my sample photos aren't that professionally taken. Most are taken by my friends or just selfies hehe.
Interested parties can email(firstname.lastname@example.com) or skype (gloriagoh_1) me for faster response. I won't give my number easily to strangers. So appreciate if you don't keep bugging me for numbers when we didn't even know each other well. Ciao!
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text:
Separate names with a comma.
Discussion in 'Lawn Mowing' started by AWILLIAMS64, Oct 23, 2011.
I was trying to figure out what this bracket was for? anyone have a clue?
It might be for counter-weights , for a bagging system. Or a deck jack.
You might try their web sight. Look for accessories for your model. I'd say possibly for several items for add on's.
looked around on their site and unless i missed something i didnt see the accessories page for the mower.
I don't think you missed anything. After I made that silly suggestion, I looked as well and didn't see a thing either. It will come be patient. I could sit here and guess one hundred things but, that won't answer the question.
The bracket is for storage of your discharge chute assembly when you remove it and install the mulch kit.
Take a look in this parts manual and you will see it listed.
i will have to try that. I tried it when i first got it and it didnt stay very well so i figured it was for something esle. May have to fiddle with it a little more to see how it really works. thanks!


text:
Skip navigation.
May 10, 2016
Thirty-four nursing students at Northwestern Oklahoma State University were honored with a traditional pinning ceremony on May 6, the day before their graduation.
Keynote speaker was Doug Coffey, chief nursing officer at St. Mary's Regional Medical Center in Enid.
Dr. Leslie Collins, assistant professor of nursing and assistant chair, presented each graduate with a pin.
The new nurses and their families also were guests at a reception in the ballroom following the ceremony.
Those completing their studies are Courtney Adams, Enid; Charisse Al-ag, Follett, Texas; Rachel Bailey, Enid; Michael Calhoun, Tallahassee, Florida; Megan Cansler, Chester; Claressa Carter, Follett, Texas; Chelsea Courcy, Mesquite, Texas; Kelsey Fly, Attica, Kansas; Julia Ford, Medford; Jessica Gulick, Enid; Laura Haftman, Oklahoma City; Chelsea Harmon, Buffalo; Tiffany Howard, Lacrosse, Wisconsin; Chassidee Koehn, Waynoka; Sadie Koehn, Alva; Lakpa Lama, Nepal, Asia; Stephanie Little, Enid; Anna Looper, Blackwell; Carol Medina, Blackwell; George Mendoza, Enid; Tandi Moyer, Woodward; Jessica Neilsen, Woodward; Ayodele Oke, Lithonia, Georgia; Humphrey Onyedili, Houston, Texas; Rebecca Reilly, Enid; Solena Rodriguez, Garber; Carrie Schanbacher, Cherokee; Merilee Stelling, Perryton, Texas; Andrea Thompson, The Colony, Texas; Megan Waters, Cordell; Katelyn Waugh, Cherokee; Deanna Westerman, Ponca City; Cortney Wheeler, Woodward; and Tiffany Wilhite, Fairmont.
MISSION STATEMENT: Northwestern Oklahoma State University provides quality educational and cultural opportunities to learners with diverse needs by cultivating ethical leadership and service, critical thinking and fiscal responsibility.


text:
Anime Eureka Seven Bleach Horrible Amines: Short Series
Are The Best: D. Gray-man Kurau Phantom Memory Classic Flood type anime
Cute love story but has lots of action
50 episodes
Movies: Spirited away Princess Mononoke Really Really Long Animes: This futurestic anime is about a scientist working in the field of alternative energy, who at the beginning of the series is on the verge of a major breakthrough in the area of "Rynax energy". His daughter Kurau accompanies him to the lab on her twelfth birthday, where an experiment goes horribly wrong and she is struck by a bolt of this energy, which knocks her unconscious. Full Metal Alchemist Avatar: The Last Airbender Websites: Justbuds.net
Youtube.com Haruhi Suzumiya the MOHS, is a show basically, about this chick, who is obsessed with people who arent really pepople, like, espers, aliens, and things like that, she makes a group, to raise awearness about this. **Lucky Star** How do i explain lucky star.. hmm.. well, Its basically about this teenage girls doing nothing in highschool. but, its funny. xD and i recomend it Inuyasha Naruto Shippuden 26 episodes
Moribito: Guardian of The Spirt Rumbling hearts
Afro Samurai
Anything with tooo much robots
His and Her Circumstances
UVERworld Sign
FLOW :D Gekidou
UVERworld Innocent Sorrow
Abingdon Boys School With You
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The key to a productive kitchen is committing to quality kitchenware. Update International kitchen products showcase affordability and quality. Invest in products that can not only get the job done, but also keep your kitchen productive.
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text:
Dr. James Matia is a highly experienced and compassionate periodontal specialist who, for over 30 years, has been devoted to giving patients the best chance to retain their own teeth for life—with minimal discomfort. Whether you are struggling with gum disease or have lost one or more teeth, Dr. Matia will give you a reason to smile again!
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text:
Hire a Data Entry Clerk
Budget $250-750 USD
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text:
Las Vegas Releases NFL Over-Under Win Totals for 2016
The schedule has been out for a few weeks and now the people from Las Vegas have given teams a win total mark.
The schedule has been out for a few weeks and now the people from Las Vegas have given teams a win total mark.
A.J. Hawk Had Ankle Surgery
Both the San Francisco 49ers and San Diego Chargers triumphed in inclement weather conditions on Sunday to advance to the next round of the NFL playoffs.
Josh McCown threw for 272 yards and two touchdowns, and the Chicago Bears beat the Packers, 27-20, in Green Bay on Monday night.
Our Kickin' Country weekend listeners were literally 'all over' this past weekend. Janelle Holsing and other hardcore country fans were at a Jake Owen/Florida Georgia Line concert in Iowa...
The Green Bay Packers were looking for answers all over in the wake of a dispiriting 30-27 loss to the Indianapolis Colts.
Las Vegas oddsmakers say $300 million or more changed hands worldwide on a controversial referee call that decided the Monday Night Football game between the Green Bay Packers and the Seattle Seahawks.
It was the Bears getting more votes this morning on the Big Breakfast. Where's the Packer fans?


text:
May 8, 2014. In this photo, Sculptor Matt Foster meets with members of the Flag Point Sculpture Committee and others to answer questions and discuss details involved in creating and delivering a major sculpture to Bucksport later this year.
This post was contributed by a community member. Submit your news →


text:
- Drop-in upgrade for AK47/AK74 pistol grips
- Fits both milled and stamped receivers, including those with grip reinforcement plates
- One-piece reinforced polymer construction with wrap-around rubber overmolding
- Hard-polymer bottom edge to reduce equipment snags or grip damage
- Includes a basic grip cap, but accepts optional Storage Cores for customized gear stowage
The MOE AK+ Grip combines reinforced polymer body construction with comfortable, wrap-around rubber overmolding for maximum weapon control in adverse environments.
A drop-in upgrade for AK-pattern pistol grips, the MOE AK+ Grip is designed to improve ergonomics and weapon control, and borrows the rubber overmolded surface of the popular MOE+ AR15/M4 grip to ensure a positive and comfortable hold on the weapon. Compatible with Magpul Grip Cores for storage customization.
All mounting hardware included.
Technical Information
Fit: AK-47, AK-74 (Milled and Stamped Receivers)
Material: Polymer Body with Rubber Overmolding
Weight: 3.1 oz with Hardware
Height: 4.1"
Thickness: 1.2"


text:
WebOverride let's you inject code snippets into any website allowing you to customize it to fit your needs
- Automatic login
- hide annoying content
- create custom shortcuts and so much more...
What does it do?
Using WebOverride you can inject HTML, CSS and JavaScript into any page in the web. You can also import any library you might need from cdnjs.com
Chrome Store
You can download the extension from the chrome store and get updated automatically when updates come out. https://chrome.google.com/webstore/detail/web-override/lllllobkincmdnjfkbknjacacmnlajll
Setup and run locally
- Clone the project
- Run
bower ithe get the components
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Developer Mode
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Load unpacked extension
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text:
Enjoy a great workout outside at one of our fitness courses. Dips, crunches, pull-ups and more.
Total of 5 facilities.
Location Notes: 8445 S. Kolin Ave.
Park: Durkin Park
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Park: Marquette Park
Park: (312) 747-6469
Location: 2540 W. Jackson Blvd.
Park: Park No. 574
Park: (312)746-5560 (Skinner Park)
Location Notes: 6601 N. Western Ave.
Park: Warren Park
Park: (773) 262-6314
Notes: Located on the Pratt side of park


text:
Smoking Tobacco Czech Republic
Smoking tobacco Czech Republic provides an in-depth and strategic analysis of the market for RYO/MYO tobacco markets. The report establishes market size and structure, analyses trends and developments for the last 13 years with forecasts to 2021. Detailed information is provided on consumption trends, grey market, product availability and development, retail pricing, taxation rates and structures, manufacturer positioning and share, brand ownership and share, national production and trade data and trends, key operating constraints and future potential, including forecasts.
The smoking tobacco market in the Czech Republic was relatively small although it is now showing signs of expansion with volumes up sharply in recent years, as a result of higher cigarette prices. Further growth is forecast in the future.


text:
1966 Wantagh Ave Wantagh, NY 11793 (800) 649-3739
Can't find the item you are looking for using the search and browse tools above? Click Here to view a wider selection that includes items we can special-order for you.
- Developed by the Boeing company for lubrication and protection of aircraft components
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Brands Cycle and Fitness :: 1966 Wantagh Ave, Wantagh, NY 11793 (Map) :: (800) 649-3739
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text:
i was working with your guys on a previous support ticket to try and delete all the inventories without being stuck on "performing actions"
i was wondering if i can just export all the tickets i have right now (more then 4800) and then create a fresh new DB and import all of them?
i think the problem is that i have been upgrading the DB since ver 2 and it probably got corrupted.
This topic was created during version 4.0.
The latest version is 7.5.00101.
5 Replies
Jul 28, 2009 at 8:33 UTC
akp982 is an IT service provider.
For this support ticket did you email them?
At the moment you cannot export and inport tickets only.
I would have said you have two options
- Delete your log files and try to delete the inventory again, may just be there too big to work with
- Send your logs to spiceworks and butter them up so they will delet the inventory or fix the database
Jul 28, 2009 at 8:40 UTC
If you create a report of all of your ticket details and save it as a CSV file you may be able to bring it back in with a modified version of the script in this how to http://community.spiceworks.com/how_to/show/203. This is not something I have tested so I am not sure it will work.
Jul 28, 2009 at 8:58 UTC
cleaning the logs didnt help (only 20 mb)
i will try the report thingy.
i opened a helpdesk ticket already but didnt get an answer regarding the export.
they suggested using sql broweser but i have no idea how to do this
Jul 28, 2009 at 9:17 UTC
i tried to export it
but the problem is that i can export only the last comment and not the whole discussion
Jul 28, 2009 at 9:31 UTC
http://community.spiceworks.com/how_to/show/560 some basics on getting into your DB with SQLite Browser.
This discussion has been inactive for over a year.
You may get a better answer to your question by starting a new discussion.


text:
Iron Chain Around Historic Monument Free Stock Photo
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text:
Girders and Rails
Ice Crystals at Epcot
The Finale – Fireworks in the Magic Kingdom
I recently read a funny thing on Boing Boing where a another guy had visited Disney World and had a similar experience to me. When you go there with your kids for the first time, you discover some secret area of your brain that Disney had been pre-wiring for the past thirty years that suddenly got a shock as soon as I entered the park, releasing an otherworldly flow of endorphins.
I think I like the reflections in the water best in this one.
Elephant Reflections
Amazing Fireworks at Disney World
This night was a special night for sure because Ethan lost his first tooth. It was also his first time ever at Disney World and the first time to see the fireworks, so it was sort of a perfect storm of magic.
He was very nervous about me pulling out the tooth, so five minutes before the show, I told him the magic of Disney would help me with the extraction. We both have a bit of wizard in us, anyway, he responded. I pulled it out and he was shocked… then just sat in awe to watch the fireworks while his dad fired away with the camera.
I took a lot of great shots of the fireworks show. It was tough to pick a favorite… but this one was right up there. I hope you enjoy it.
The Main Street Confectionery
You can't go wrong with Disney's main street at night, can you? It's okay to forgo the extra calories with all that walking… at least that what I kept telling myself.
Also, I didn't realize before going that the castle changes color every few minutes with tons of different lighting configurations. You can see the warm orange colors in the large version below.
The Scary Apothecary
The Haunted Tower
Here is the Hollywood Tower Hotel thing in Disney World. We waited, of course, until midnight to actually go on the ride. It was great fun and the coolest thing about it is the ride is different whenever you get on it. There is a randomizer that goes through one of a few set programs that changes the way the elevator flies up and down the hotel. It's really crazy. Also, I recommend NOT carrying a tripod on the ride. That was a mistake.


text:
Antillean Confederation
|This article needs additional citations for verification. (October 2008) (Learn how and when to remove this template message)
The Confederación Antillana or Antillean Confederation was the vehement idea of Ramón Emeterio Betances about the need for natives of the Spanish Caribbean to unite into a regional entity that would seek to preserve the sovereignty and well-being of Cuba, the Dominican Republic and Puerto Rico.
Its main idea was to subsequently end European colonialism in the Americas as well as a response to the Monroe doctrine phrase America for the Americans, which Ramón Emeterio Betances changed into Antilles for the Antilleans. The main gathering point of the idealists was San Felipe de Puerto Plata, Dominican Republic.
Strong supporters of this idea:
- Eugenio María de Hostos[1] also known as The Citizen of the Americas
- Gregorio Luperón hero of the Dominican Restoration War.
- José Martí often referred to as The Apostle of Cuban Independence.
- José de Diego
- Ramón Emeterio Betances


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NCR ATMs
The Exatec ATM factory completely re-manufacture ATMs from the main brands.
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text:
Elisabetta Gardini
Yearly Forecast for 2017
Elisabetta Gardini is a female celebrity.
She was born on Sunday June 3rd 1956, in Padova, Italy,.
During 2017, Elisabetta Gardini has to be ready for major changes. She will be inspired to start new projects or enterprises. Elisabetta will feel a strong forward push toward new goals. This is a time for vision and planning. Gardini should share her dream with others; make plans, get the necessary support, but, above all, rely on herself as the driving force, and most importantly - be decisive!
Elisabetta Gardini is starting a new nine-year Epicycle. Everything she does now will affect her future. Elisabetta must not hold back the inner force of creation. She needs to be direct, daring, and bold.
Gardini will have more confidence and determination this year, particularly in comparison with last year, which was a time of letting go. This year represents a time of birth. It is a time to take charge and to apply herself to her dream. This is also a good time to make the personal changes Elisabetta Gardini has long wanted to make: start a diet and/or an exercise program, or begin a new course of study.
There may be some emotional turmoil, especially in the first two or three months. It takes a while to get the ball rolling. There are many changes Elisabetta must make and much work to be done. She should be open-minded, organized, and focused, while avoiding distractions and procrastination.
Gardini is at a crossroads. She will need courage and a clear head to stay on the right track. This is a year of opportunities.
The key months in Elisabetta Gardini's year of 2017 are March, in which Elisabetta is able to lay the foundation to her plans; April, in which changes take place such as a change of residence or career; July and August mark a time in which Gardini will see the fruits of her labors begin to take place; October 2017 represents a major turn in events, often fraught with emotional turmoil; the fall marks a coalescing of Elisabetta Gardini's plans into more concrete form.
Let's take a look now at Elisabetta's monthly forecast for July 2017.
You and Elisabetta
About Elisabetta's Personal Year Cycle
In numerology, each year of Elisabetta's life is part of an evolving pattern that can be described as a nine-year cycle or epicycle. These cycles begin at Elisabetta Gardini's birth and progress, one by one, through nine steps that complete an epicycle, and then begin again.
Read more about our numerological yearly forecast for


text: Posted June 4, 2014 Not looking good for cris scott he is so out of shape by the sounds of it. If someone has any video of KB that would be great! Sent from my SM-G900P using CarolinaHuddle mobile app Share this post Link to post Share on other sites


text:
The Green Bay Packers completed their second round of open OTAs Tuesday. Here's five takeaways from the day's happenings.
In addition to the same players that missed practice last week, the Green Bay Packers have a new trio of players absent from Tuesday's Organized...
The Packers will hold practice open to the public Tuesday at 11:30 a.m. CT at Ray Nitschke Field.
The first round draft choice of the Packers was forced to watch as Micah Hyde lined up with the first-string defense at safety during OTAs.
From Micah Hyde at safety to the first Julius Peppers sighting of 2014, there was no shortage of topics discuss following the first open practice of the season.
There's a now-or-never feeling about Sherrod in 2014. Does he deserve first crack at being the top backup at the tackle position?
The first open practice of the 2014 season takes place at 11:30 a.m. at Ray Nitschke Field.
OTAs will provide a glimpse into how far several Packers players have recovered from injuries last season, such as Clay Matthews, Bryan Bulaga and Casey Hayward.
The free agent tight end is reportedly being checked out by the Packers medical staff on Wednesday.
The Packers can begin Phase 3 of their offseason training program on Tuesday.
The Packers are still lacking for depth at the safety position. OTAs are the perfect time to find out if Hyde can play the position.
Friday is the final day of OTAs in Green Bay. The Packers will practice on Friday, but it won't be open to the public.
B.J. Raji, Desmond Bishop and Matthew Mulligan are a few of the players Railbird Central analyzes as Week 2 of OTAs comes to a close in Green Bay.
The Packers will practice on Thursday in Green Bay, but the session will not be open to the public.
Mike Conklin of Packerpedia.com joins Railbird Central to give us his take on Packers practice this week in Green Bay.
Despite graduating from a drug rehab program last week, Johnny Jolly wasn't at Packers practice on Tuesday. That and more in today's Daily Links...
Practice takes place at 11:30 a.m. at Clark Hinkle Field in Green Bay on Tuesday in a session open to the public.
Chris Terlop of WDUZ in Green Bay joins Railbird Central to talk about the first open practice of Packers OTAs.
From the cornerback situation with Casey Hayward and Sam Shields to J.C. Tretter's injury, Brian Carriveau digs in with his opinions from Packers OTAs.
Phase Three of the NFL's offseason begins Monday in Green Bay with the start of Organized Team Activities.
And Donald Driver will be hoping to win ABC's Dancing With The Stars. The season finale airs Tuesday night beginning at 7 p.m.
Wide receiver Donald Driver performs in the final week of competition on ABC's reality television show.
Packer fans are understandably nervous watching as players for rival teams start organized workouts as the lockout stretches on into the summer.
The NFL has released the dates for Organized Team Activities with Mini-Camp dates to follow soon.


text:
47-mile long iceberg breaks off of Antarctica
WASHINGTON (AP) An iceberg 47 miles long and 4.6
miles across has broken off the Ross Ice Shelf in the Antarctic, the National
Ice Center reported Thursday.
The giant sheet of glacial ice and snow was named C-18,
meaning that it's the 18th iceberg to be tracked in that section of Antarctica
since 1976, when record keeping began.
The iceberg, floating close to the ice shelf, is not considered
a hazard to navigation. It was spotted on satellite images.
The discovery comes just under a month after a much larger
iceberg 40 miles by 53 miles broke away from another part of Antarctica.
That iceberg is known as B-22.
Also in March, a large floating ice shelf in Antarctica
collapsed. The 1,250-square-mile section of the Larsen Ice Shelf collapsed during
a five-week period that ended March 7. It splintered into a plume of drifting
Neither the ice from the icebergs nor from the part of
the Larsen Ice Shelf that broke up will cause the sea level to rise when it
melts because it was already floating. Scientists say that the icebergs and
the breakup of the ice shelf are not necessarily sure signs that the global
climate is warming. In fact, the ice in parts of Antarctica is growing thicker
as some areas of the continent are cooling off slightly.
The National Ice Center, based in Suitland, Md., provides
worldwide ice analyses and tracking to assist the military and private shippers.
It is a joint operation of the Navy, National Oceanic and
Atmospheric Administration and Coast Guard.


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Do you prefer open space over cubicles?
Do you like to venture in the unknown to accomplish greater things?
Do you want to be part of a great adventure?
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text:
First Published in 1996. Routledge is an imprint of Taylor & Francis, an informa company.…
Paperback – 2017-10-31
Rolland's biography attempts to provide an overview of Handel's life and works from his early lessons in music to the classical context in which he is commonly placed. Originally published in English in 1916, Hull's translation gives an insight into biographical facts and the musical pieces…
Paperback – 2017-07-12
Routledge Revivals
First Published in 1997. Routledge is an imprint of Taylor & Francis, an informa company.…
Paperback – 2016-09-28
Music of the New American Nation: Sacred Music from 1780 to 1820
This essential reader includes Thomson's essays on making a living as a musician; his articles on classic composers; his relation to his contemporaries; his articles on newcomers in the music world, including John Cage and Pierre Boulez; his autobiographical writings and commentary on his own works.…
Paperback – 2016-05-13
Aaron Copland (1900-1990) is generally considered the most popular and well-known composer of American art music, and yet little scholarly attention has been paid to Copland since the 1950s. This volume begins with a portrait of the composer and an evaluation of significant research trends which is…
Paperback – 2016-05-13
Routledge Music Bibliographies
Ralph Vaughan Williams: A Research and Information Guide presents the most extensive annotated bibliography of its subject yet produced. It offers comprehensive coverage of the English composer's prose works and accounts for over 1,000 secondary sources from all critical and scholarly eras. A…
Hardback – 2016-04-05
Routledge Music Bibliographies
This book presents the musician in dialog with a Polish-Canadian musicologist and three of his Dutch friends and collaborators, Reinbert de Leeuw, Elmer Schönberger and Frits van der Waa. Topics include his artistic evolution, his relationship to minimalism, his prevalent interest in mysticism…
Paperback – 2016-03-03
Studies in Contemporary Music and Culture
First Published in 1999. Routledge is an imprint of Taylor & Francis, an informa company.…
Paperback – 2016-02-28
This book, first published in 1934, contains the recollections of the varied and coloured life of a great pianist and composer, who is one of the most striking figures of the musical world. Rachmaninoff dictated his memoires to the author of this book, and much of the story is therefore told in the…
Hardback – 2015-03-09
Routledge Revivals
From the diverse proto-theatres of the mid-1800s, though the revues of the '20s, the 'true musicals' of the '40s, the politicisation of the '60s and the 'mega-musicals' of the '80s, every era in American musical theatre reflected a unique set of socio-cultural factors. Nathan Hurwitz uses these…
Paperback – 2014-06-20
William Alwyn: A Research and Information Guide is a catalogue, discography and annotated bibliography of the nearly 500 works of this twentieth-century British composer. It will be invaluable to twentieth-century British composer researchers and aficionados, music history courses, and…
Hardback – 2011-08-25
Routledge Music Bibliographies
Recognized as the primary American symphonist of the 20th century, Roger Sessions (1896-1985) is one of the leading representatives of high modernism. His stature among American composers rivals Charles Ives, Aaron Copland, and Elliott Carter. Sessions was awarded two Pulitzer prizes, election to…
Paperback – 2007-12-05


text:
The House of Hulshoff is a property sold in Fable III in Silverpines. It is located in a ring of small cabins deep inside of the area.
Stats Edit
Base value: 2,670 gold
Base income: 97 gold[1]
Location: Silverpines, Village. To the right of the mine entrance.
References Edit
- ↑ Walsh, Doug and Epstein, Joe. (2010). Fable III Signature Series E-Guide. BradyGames. p. 264. ISBN-13: 978-0-7440-1302-3.


text:
QuickTime Lite 1.43
What Is the FileHippo Safety Guarantee?
We know how important it is to stay safe online so FileHippo is using virus scanning technology provided by Avira to help ensure that all downloads on FileHippo are safe. The program you are about to download is safe to be installed on your device.
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Languages: Multiple languages
License: Freeware
Date added: March 25, 2005
MD5 Checksum: Not calculated


text:
Advert for new students into Higher National Diploma (HND) Chemical Engineering
Interested prospective students are hereby requested to apply for admission into higher national diploma programme (HND) in chemical engineering.
- Holders of national diploma in chemical engineering from federal polytechnic nekede and other equivalent institutions with a minimum of lower credit (2.50)
- Candidates with pass level and CGPA not below 2.00 points, a minimum of two years post ND cognate experience is required. (Applicable to Federal Polytechnic Nekede ND graduates only).
- Candidate with five credit O'level passes at WASSCE or its equivalent at not more than two sittings in the following subjects; Mathematics, English, Physics, Chemistry and any one subject from Biology/Agric. Science, Engineering Drawing, Technical Drawing, Basic Electricity/Electronics, geography, Economics/Commerce, English, Metal Works, Wood Work, Computer Studies/ICT Data Processing.
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Applicants can start and complete this process from any location in the country. It is advisable to minimize journeys to owerri for the purpose of completing the form.
CALL 08087000802, 09055590766 for (HND),
Mr. I.M. Aligbe


text:
Posts Tagged 'Orbit'
WIP: Lost in Space (working title)
April 5, 2011 3 comments
You awake in a space station. Why? What's your mission? Survive?!?
Explore the space-station, a complex building in earth-orbit. Lost in Space is not (yet) a shooter, it's more like a 3D-Jump&Run.
Inspired by the movies 2001 and Cube, also by the game Portal. This map is still under development.
>> Download Lost in Space – BETA 1
Categories: FPS Creator Levels, Work in progress Ego-Shooter, FPS Crator, FPSC, Jump & Run, Level, Map, Orbit, Space, Station, Weltraum, WIP, work in progress


text: He and Terranova said there's no reason to believe that investors are fearing another market correction. Najarian said if there were fear in the markets, the volatility index would be running at 30% to 40% instead of 20% currently. Kelly said utility stocks are extremely attractive for their "nice, fat" dividend yields. "These things are never going to fail," he said. Pisani noted that Powershares DB Commodity Index ( DBC), with a 9% gain in the past six months, as a good ETF growth play. Terranova agreed, saying it's a great ETF to own because "it's all about the emerging-market recovery." But Cortes disagreed, arguing that the commodity trade has become extremely crowded, especially in gold. "We are going to see pain in commodities." Pisani noted that oil hit a seven-week high today. Terranova attributed the rise to an anticipated large flow of from commodity index ETFs that want exposure to energy, especially oil. He said the oil trade will turn flat by the middle of January. Cortes said he's shorting oil because he thinks the rally has been extended. Shifting to technology, Najarian continue to be high on chip stocks. He noted Marvell Technology ( MRVL) received a new price target of $25 from an analyst and draws 50% of its revenue for storage. He said Seagate ( STX) has fetched a price target of $22 from an analyst. He said the story behind these stocks is the growing demand for data storage. Pisani referred to a chart from Investors Intelligence that pointed out that the bears are in hibernation to an extent not seen since 1987. Kelly said the chart made a good point, but Terranova argued that there is no evidence to suggest "we are near a top."


text:
Paprika Ombre - DiscontinuingNutmeg Fibers
A rich, fall orange that reminds us of sugar maple leaves changing their colors. We love the way this looks when paired with our Cabin base. We blend just the right recipe of eco-friendly, non-heavy metal dyes, then dye Cabin slowly until just the right hue appears. Our ombre's fade gently from a dark tone to all natural to create a variegated stripe pattern. Slight differences may appear between dye lots due to the fact that we hand-dye our yarn in small batches. As with all our yarns, hand wash with cold water and lay flat to dry.
**We will be discontinuing this colorway when sold out as we transition to use 100% natural dyes on all our fibers.**
- Bulky weight
- approximately 100g/106yds
- 70% US Alpaca/30% US Merino
- 3.0-3.75 stitches = 1" in stockinette
- US 10-11 needles


text:
An interiors, vintage style and crafts blog, Patchwork Harmony features inspiring ideas for your home from vintage and thrifty finds to independent designers and makers. We share DIY tutorials, handmade ideas as well as shopping tips for vintage lovers and interior styling advice for your home. Part of the Patchwork Harmony brand which includes online digital publication 91 Magazine, as well as freelance writing, picture research, design and creative small business advice.
Thursday, January 28, 2010
Vintage Style Vessels
7 comments:
Oh yes, I'm totally into vintage glass bottles at the moment. It's becoming a bit of an obsession... xxReplyDelete
I completely agree! They look stunning at dinner parties with a single flower in each :)ReplyDelete
I couldn't agree more. I have to tear myself away!ReplyDelete
These looks amazing.. I have a few.. but they dont look as good as the ones in the picture..ReplyDelete
You've got an amazing blog.. Can I feature it on my blog??
Patricia - of course, feel free! ;) thank u xReplyDelete
i love stuff like this, they are so pretty with little posies of flowers in them :) unfortunately my boyfriend doesn't seem to understand the asthetic!ReplyDelete
I love vintage bottles too. Infact the third one {Max Attenborough} is taken in my kitchen!ReplyDelete


text:
Full size lost in space robot part chest lenses.
- Sold for: Start Free Trial or Sign In to see what it's worth.
- Item Category: -
- Source: eBay
- Sold Date: Jan 03, 2007
- Channel: Auction House
Building a full size lost in space robot? Or a prop replica from the same show or time tunnel? These dialight panel indicator lenses are exactly what you need. On the LIS B9 it's the two large white chest lenses. Still sealed in plastic.


text:
Robert Taicher
Rush to War
Filmmaker Robert Taicher explores the events leading up to the Iraq War in this penetrating documentary. Taicher provides a thorough examination of mistakes made by several administrations; the rationales presented for going to war; and the effect of events on America's society, security and international credibility. Bonus features include an exclusive interview with former Ambassador Joe Wilson, husband of outed CIA agent Valerie Plame.


text:
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Nabídky práce: Optotune AG
Optotune is a strongly growing and internationally active optics company based in Zurich, Switzerland.
We develop, manufacture and market the latest generation of adaptive optical elements for industrial
and consumer markets. Optotune's vision is to enable our customers to create innovative products by
providing them with unique optical components.
Nabídky společnosti e-mailem


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Hello. Some time ago, the Gimp stopped responding to my mouse in the image window. In other windows and on menus the mouse works fine (ie I can select brushes and such and use the interface without problems), but in the image window (or more precicely, the canvas area) it's as if the mouse doesn't even exist. All kinds of clicks are ignored, the rulers doesn't show the position of the cursor, and the position in the lower left also isn't updated (it is set once upon entering the window, but after that it's dead). My tablet still works fine, but not being able to use the mouse for anything is somewhat annoying.
This originally happened out of the blue one day while using Gimp 2.2.11 (I unfortunately have no idea what caused this to happen). I tried upgrading to 2.2.12 and then 2.3.13, without success. I also deleted the ~/.gimp* directory in the hope that regenerating the config would fix the problem, but no. No matter what I do, I can't make the Gimp recognize the mouse in the image window. The mouse isn't anything special, and it used to work with the exact same X config I've got now. I haven't changed the xorg.conf file in several months. The Gimp is the only application with this problem. This is on a dual-core amd64 processor in 64-bit mode (haven't tried 32-bit), Linux kernel 2.6.18, Xorg 7.1. Does anyone know what might be causing this, and how to fix it ? Thanks, ~ Gerry _______________________________________________ Gimp-user mailing list firstname.lastname@example.com https://lists.XCF.Berkeley.EDU/mailman/listinfo/gimp-user


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Food spots add a dash of flavor in 1st season
Credit: Chitose Suzuki
Don't have a ticket to the game? Grab a seat at one of these new Fenway-area hot spots:
The Hawthorne (500A Commonwealth Ave., 617-532-9150, www.thehawthorne bar.com) is an upscale cocktail lounge beneath the lobby of the Hotel Commonwealth. It's drawn rave reviews from local libationists and beyond as one of the best new bars in the nation since opening last year.
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