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wikiHow to Make a Poster Using Microsoft Word
If you need to make a professional poster, it's easy to do so in Word. By creating a box and formatting it to fit your needs, you can make a poster that looks much better than one you'd draw by hand. Once you're happy with the poster you have, print it out and make some copies!
1Go to the little tabs on the top left, go to the one that says, "Format" then go to border and shading - click on that, then select page border, and select the box setting.
2Choose whatever line style and color, and thickness you want the border to be.
3Hit OK and click on the view tab on the upper left corner. Click on insert toolbars and drawing. A section should come up on the bottom of your screen.
4If you want a title on your poster, use word art. To do that, click Insert, then select Word art, or just click the big fancy letter on the toolbar below.
5Then, click on the little 'newspaper' thing on the on the tool bar, (Giant A with lines around it)
6Drag the box around, and click the paintbrush (on the bottom) and select the same color line as the border. Also on the line thing make it the thickest.
7Insert your picture. You can either copy and paste or insert from a file.
8Repeat these steps until you have a poster!
Community Q&A
How do I overlap a picture in Microsoft word?wikiHow ContributorRight-click on the image and click the Options. Press either "send to front" or "send backwards".
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How to make a poster for information?
Can the poster be printed with high resolution quality for the size of 3 mt wide x 4 mt long?
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- Make a page border to make the poster more attractive.
- If you want to 'WOW!' people, you can just copy and paste pictures and click on the little thing that says auto shapes and you can use any little bubble you want!
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Categories: Microsoft Word
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Español: hacer un póster utilizando Microsoft Word, Русский: сделать постер в программе Microsoft Word, Italiano: Fare un Poster Utilizzando Microsoft Word, Português: Fazer um Pôster Utilizando o Microsoft Word, Deutsch: In Microsoft Word ein Poster erstellen
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Liz Fies
The Fies Sisters (Lis Fies and Brenda Fies) are playing PollyGrind IV! Our short film CONSUMED is at 6pm Friday October 11th, and our feature THE COMMUNE screens Sunday October 13th at 2:30pm.
Unfortunately for his fans, Hero Fies will be holding down the fort in L.A. Maybe next red carpet he'll high-paw you?
Thank you Chad Clinton Freeman, Chemical Burn Entertainment, and Uncle George.

subset: commoncrawl


text: RT Video/DVD DB /z-wcorg/ DS http://worldcat.org ID 191886930 LA Closed-captioned. T1 Life after people A1 DeVries, David., Lopez, Vincent., Lurie, James, Flight 33 Productions (Firm), History Channel (Television network), Arts and Entertainment Network., New Video Group., PB A & E Television Networks : Distributed in the U.S. by New Video PP [New York, N.Y.] YR 2008 SN 1422909395 9781422909393 AB What will the world be like when mankind is extinct? The pyramids may stand forever, but the cities will disappear. Our greatest masterpieces will fade and crumble. As global warming and the depletion of natural resources become ever more pressing issues it is critical to consider how we can reduce our impact on the planet. Journey to locations around the globe already going through the processes of a lack of human intervention. See the changes wrought in just decades in ghostly settlements like Chernobyl, which was abandoned since only 1986, and island towns off the coast of Maine. How long would it take before the last remnants of mankind completely disappeared?


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In the Nationals' clubhouse, Blake Treinen occupies the locker closest to the entrance, in the corner where minor leaguers congregate in early spring. It is a place for extra arms and kids getting their first taste. The players in the row next to Treinen have packed bags and headed to the minor league complex.
The empty stalls symbolize his status at the start of camp. The equipment remaining inside Treinen's locker symbolizes his revelatory performance. Even he didn't think he would have a chance to make the team with a week left in spring training. But he does.
"It's a pleasant surprise," Treinen said. "My intentions and expectations coming into spring training were just to leave an impression. The fact that I'm still around is an absolute blessing. I'm just trying to make the most of it. Whatever their decision is at the end of spring training is their decision. I feel like I've done my absolute best to leave an impression with the big club."
This afternoon, in the Nationals' 2-0 loss to the Cardinals, Treinen left another impression. He entered in the eighth inning and faced two batters. Star catcher Yadier Molina grounded out to shortstop, outfield prospect Randal Grichuk struck out looking. Treinen threw his vicious sinker, which hit 98 miles per hour earlier this spring, between 95 and 97 mph.
"Easy 96 with some sink," Manager Matt Williams said. "He continues to impress."
"Powerful," one NL scout texted. "Stuff definitely plays up out of the 'pen."
"Excellent!" another NL scout texted. "Good delivery and mound presence."
I asked the second scout if Treinen was one of the Nationals' 12 best arms.
"Absolutely!" he texted back. "Kid can pitch on a lot of major league staffs right now."
Treinen has dazzled the Nationals and the league during spring. His usage suggests they're considering him in a bullpen role. A starter last year in Class AA Harrisburg, Treinen had been stretched out earlier in camp. Today, the Nationals planned to give him an inning at most. He has relieved in the past, and feels comfortable in the role.
Still, it will not necessarily be easy to put him on the opening day roster. Treinen is not on the 40-man roster, which means the Nationals may have to sacrifice a player – likely either Jhonatan Solano or Jeff Kobernus – in order to put him on the team.
And while Treinen's arm is undeniably electric, there are questions if his stuff outpaces his results. For such a hard thrower, Treinen has never posted big strikeout totals or a small hit rate. Last year at Harrisburg, he stuck out 6.5 batters and allowed 9.5 hits per nine innings. This spring, Treinen has allowed five earned runs on 15 hits and three walks in 9 2/3 innings.
"He's still trying to make his stuff play," the first scout said. "He's got a great arm, no doubt. But he still doesn't miss a lot of bats."
Regardless, the Nationals have buzzed over Treinen's potential since the start of spring. His presence in the organization is a clear victory. He came over along with A.J. Cole and Ian Krol in the deal that sent Michael Morse to Seattle. Treinen is turning heads, Cole is the Nationals' No. 2 prospect and Krol became part of the deal that landed Doug Fister.
The trade did wonders for Treinen, too, he said. In 2012, at High-A Stockton of the hitter-friendly California League, Treinen went 7-7 with a 4.37 ERA. Then 23, he felt like he was spinning wheels.
"Coming to this organization is probably the best thing that could have happened to my career," Treinen said. "Just the whole outlook on pitching and philosophy and throwing program, it's just taken my career through the roof, more than what I would expect it to be right now."
The mention of the Nationals' throwing program seemed particularly interesting. Treinen chose his words carefully and made clear he meant no disrespect to Oakland. With A's, he never threw more than 120 feet, and coaches instructed him to throw on a line. The Nationals allow more freedom to play long toss.
"You just need to feel your body out," Treinen said. "It's allowed me to know my body better than it is a regimented program as opposed to doing what's best for you. Not that everybody at Oakland did that. For me, it works better here. Something clicked here."
Treinen has also felt welcomed in his first major league camp. Stephen Strasburg and Craig Stammen have both offered advice.
"Everybody is so willing to help each other," Treinen said. "I can't thank the organization – top to bottom, players and stuff – for just being open in every aspect of the game."
>>> Gio Gonzalez had an uninspiring fourth start of spring. He worked up to 82 pitches, which was the main goal and what matters most. But he allowed two runs (one earned) on four hits and three walks in 4 2/3 innings and did not strike out a batter – which is something that's never happened to him 153 career regular-season starts. "Didn't have my best stuff," Gonzalez said.
Gonzalez has faced the Cardinals a couple times this spring, and he believes that threw him off a bit.
"It's been a challenge against a team I've faced plenty of times," Gonzalez said. "A team that's seen you so many times, your job is just to work on what you can, mix it up as much as possible."
Williams didn't buy that.
"Not really," Williams said. "Not at this point. It's about his pitch count and him throwing his pitches where he wants to throw them. A little bit of a struggle today with command of his fastball. But other than that, it was good."
>>> Anthony Rendon did not travel with the Nationals and has been laid low by the chest cold that has been going around the clubhouse. "He may be down a couple days," Williams said. "He's been feeling bad."


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We are very responsible for duty free cigarettes, rarely have quality problems.
GYN in central NJ I'm really happy with Hills OB/GYN (offices in East Brunswick Hillsborough). deliver babies at St. Peter's. They have many doctors to choose from and since they recommend you meet them all for pre natal check ups, you get to see who you click with best for future regular visits. The wait times can vary. The worst I ever had was minutes in the waiting room and another 30 minutes in the exam room ack! But that was definitely exception. also young hip, very easygoing I she moved here from California and you definitely get that mellow vibe from herDr. Cernadas She delivered my son and it was the first time I met her! She doesn't have a warm fuzzy personality, but man is she a good, competent doctor and great surgeon (I had an emergency c section)Dr. Beim kind of has a fatherly vibe, a bit old school, relaxed attitudeDr. Salley didn't like her at first she is kind of loud. But met with her several times and grew to really like her. A very caring bedside manner. Okay, and my personal opinion, but. I'm not a huge fan of Dr. Johnson (she was a little to by the book for me you will be induced at 40 weeks!!!) or Dr. Karanikolas (women think "tall, dark handsome" and he it. I don't have time to fawn over my doctor!). I only met Dr. Lobosco once and I expressed about something, he was like "it's no big deal don't worry about it." That may have been true it was an "I'm the doctor and I better than you" of my feelings left my feeling so great the interaction. I never met Dr. Cho so I can't say a good or bad thing about him. So there you go. I see the obgyn team at Robert Wood Johnson University Hospital in New Brunswick. I work directly with Dr. Todd Rosen (MFM) because I'm high risk. But, I've also seen Dr. Merjanian, Dr. Pradhan and Dr. Balica. I've liked them all. If I wasn't working directly with Dr. Rosen I would choose to see Dr. Merjanian. She is warm, friendly and really listens to you when you talk. I never feel rushed and I never wait too long (about 15 minutes at the most). They are based in Kendall Park, NJ but also have offices in Manalapan and Lakewood. They are affiliated (obviously) with RWJ Hospital. They are a team of 6 doctors and they are all fantastic. My OBGYN is Dr. Lundberg and he's so great even my husband can't stop raving about how wonderful he's been. He saw us through a miscarriage as well as our pregnancy and birth of our now 2 1/2 month old son. All the nurses are great, the doctors are all professional, caring, great senses of humor it's an all around top notch practice.


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UNC vs. Maryland: Live Score and Analysis for ACC Tournament 2013March 6, 2017
The North Carolina Tar Heels held off the Maryland Terrapins' many advances in today's second ACC tournament semifinal contest to win and advance to the finals.
North Carolina led by as many as 13 points in this game and had a double-digit lead in the second half, but Maryland had a chance to tie it on the last possession.
Unfortunately, Logan Aronhalt heaved up a desperation shot with 10 seconds left that was a horrible air ball, and North Carolina held the ball until the final buzzer sounded.
UNC will advance to play No. 9 Miami in the finals of the ACC tournament, whereas Maryland's future is now uncertain.
Even after its win over Duke in the quarterfinals, Maryland is on the outside looking in when it comes to the NCAA tournament, finding itself in Joe Lunardi's Next Four Out. Failing to beat UNC might have been the final nail in the coffin, and the Terps will likely play in the NIT as a No. 1 seed.
Final Score: North Carolina 79, Maryland 76


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This virtually forgotten release from 1956 on Chicago's Argo Label is a classic Mike Simpson, on tenor sax, doing a snazzy spy lounge snapper with JUST the right amount of 007 meets Sammy Davis, Jr. and that 50s space-age boozy vibe.
January 13, 2017
This virtually forgotten release from 1956 on Chicago's Argo Label is a classic Mike Simpson, on tenor sax, doing a snazzy spy lounge snapper with JUST the right amount of 007 meets Sammy Davis, Jr. and that 50s space-age boozy vibe.
August 11, 2016
This a Serbian folk tune which is probably a traditional and has no one author, but through time has changed and evolved as generations of musicians have played it and sang it millions of times. "Nas Dva Brata" in the Serbian language is "Us Two Brothers" in English. Two piece vocal duo, guitar and accordion for accompaniment. I would call this a rustic, Balkan toe-tapper, and a great drinking song; and I just love the Italianesque, but very Balkan as well, guitar string work and dense, quick harmonies coming off the accordion against the vocals. Released on Chicago's PERUN label in the late 1940s, I'm guessing.
July 23, 2016
This is from Hampton's "New Movements in Be-Bop" album (1947) which is a real treasure of the initial be-bop storm that was happening in New York in the 40s. Featuring a young, hungry Charles Mingus on bass playing his own composition, the futuristic "Mingus Fingers", Hamp's orchestra is as spirited, and tight, as ever.
June 10, 2016
Such a great great jumpy blues, a hopper and a skipper for them alive ones; tappin' away on repeat at home, too. Crudup outdoes Elvis by some 10 years. Made in Chicago.
Arthur "Big Boy" Crudup, voice & guitar
Melvin Draper, drums
December, 1944
April 13, 2016
This is a Greek Decca, #4056. "O riQProE" is my English alphabet translation of the Greek title. I have no clue about any of the information on this label, unfortunately.
But the tune is a wonderful Greek folk-dance number, almost like a very sophisticated waltz; with harmonized vocals, compound rhythms and perfect string interplay.
March 15, 2016
Not much information to be found on Pickard's Chinese Syncopators. They were an active string band on the Vaudeville circuit in the 1920s & 30s, and seemed to be an all Filipino combo: probably easier, and catchier, at the time to say Chinese instead. This is a cool and quirky rumba called "Ali Baba".
This is on an English-made His Master's Voice. Enjoy with a singapore sling!
March 4, 2016
Florencia Morales Ramos, "Ramito", is one of the kings of Puerto Rican Jibaro music. Born in 1915, in Caguas, PR, he was considered a really good singer by the age of thirteen; and by the late 1930s he was a renowned star. He had a long career, even playing for JFK at the White House in 1961 in a huge showcase of Puerto Rican talent.
"Una Mujer en Mi Vida" is a bolero son, and totally infectious. It is full of those famous conga rhythms, horn lines, and vocal harmonies which really make so much of Puerto Rican music so sexy and hip-swerving. And of course, Ramito's beautiful tenor just soars.
Recorded in New York, NY, on the rare BMC label.


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Vill du ange som standardvaluta eller gäller valutan endast för detta besök?
Location and modern rooms.
very good location and room is comfortable...
Everything very sleek and modern, very friendly personnel, very clean, good location, overall very pleasant experience. unlimited 24 hr WiFi a bit expensive (22 Euro), but worked well. missed the possibiltility to order at least something small to eat on the room (apart from breakfast), but since they don´t have a restaurant, I guess that´s a bit difficult to manage.
Good and quiet loction, nice interior, very kind hotel staff, perfect hotel for business trips.
It's centrality. Noise in the morning hours from the area of Rosie's and, we assume, people departing the nearby nightclub.
Perfect location, nice and clean room, very friendly staff. Extremely slow elevator
The helpfulness of the staff. The room was very small, there was no restaurant facilities for dinner, the bar area was merely an extension of the reception desk and there was no tea and coffee making facilities in the room
The hotel is near Köningsallee shopping street and the old city.
Everything was ok- staff are very polite, breakfast is good, rooms are comfortable I was second time in this hotel and all the time is was a problem with water in bathroom (it was plug) but they fixed after asking
The hotel was clean, the location was close enough to the main train station, aldstadt, Konigsalle and all the sights. The staff were friendly and welcoming. The bathroom door was see-through glass, so you can see someone using the toilet from the bed, you would want to have no inhibitions about sharing EVERY bodily function with whoever you happen to be sharing with. Our double room had 2 single beds pushed together and 2 single duvets, they were also on castor wheels so some some mornings we would find our beds had drifted a few feet apart. I would not return because of this point alone.There is only one slow elevator for 5 floors and over 100 rooms, On our day of departure it was out of order and we were on the 4th floor. Finally breakfast is €19 each and another €6 if delivered to your room, so if you fancy a romantic breakfast in bed for two some morning it will set you back €44!
Very good size rooms, and although close to city centre location was very peaceful
apartment is clean and very spacious, Location is good There is no guest elevator, you have to climp three floors to reach your apartment, No daily cleaning service, Front disk close at 5PM and week ends.
Convenient location, very friendly staff, comfortable. office staff only on premises during the hours of 8am-6pm. Not a problem if you talk with them prior about your specific needs.
Right in the center and surrounded by nice shops, parking within the property, size of the room (was 50-55sqm), large washing basin, good heating system, good size kitchen Elevator was very small and hard to bring up large bags, doona smelt smoke and made our pyjama smoky in the morning, corridor lights were hard to find in the dark
Spacious room with living space, large bed, kitchenette. Quiet location close to Altstadt and KO. Friendly staff. They didnt arrange a parking space for our car, althought we required one with our reservation weeks ago. It was told us that a parking space might be available only for the last two days, but the enterance was closed at the weekend and there was no one at the office. Internet didn't work during our stay for 5 days, althought we told them repeatedly. It only worked 5 minutes each day, which was very disappointing. The room design and furnitures are quite old-fashioned. No cleaning for the whole 5 days, while the price range is higher than a 4 star hotel.
The attitude of the staff was very nice. Staff were helpful and supportive. I liked the environment. The only issue we faced was no Air Condition facility. If A/C is offered even with an additional charge, it could be perfect.
Good Location No reception staff on weekend, unable to park car in garage as nobody there to let us in. We were given a smokers room - were are non-smokers but there was no one at reception to change anything.
Mostly businessat Dusseldorf airport but went out and about in the evnings to restaurants and bars Non refundable deposit was a bit harse as we had to leave for a few days in the middle of ou stay and go to Munich.
Utmärkt service och bra frukost Det är 150m till P-hus, jobbit med bagage att gå till hotellet!
Location, excellent breakfast ......
Trevlig personal, bra läge, prisvärt, god frukost, bra rum. Saknar fler engelskspråkiga kanaler. Dålig ventliation i toalett (immade igen direkt).
Bra läge med trevlig personal i receptionen. Frukosten var ok men något dyr Hade väntat mig mer för priset
good breakfast, central located (x-mas markets and shopping area), nice hot shower
Location, rooms
everything in the room was clean and the price / quality was good. There is a minibar so if you want anything, it is available. The walk into the city centre is about 20 minutes and is a nice doable walk. The breakfast is very nice, nice bread and rolls and lots to choose from. the bathroom was really too small. The toilet was wedged between the showerglass and the wall. If you are a little bit big you wil just not fit in. The towels in the hotel were very old and thin.
it was close to shopping area not as clean as other hotels
friendly and clean rooms the pillows needed to be replaced but otherwise nice
Lights in bathroom, broken.
Hotel was very clean and the staff friendly. Very good buffet breakfeast.
Good location, Good Breakfast very small single room located at 3rd.Floor with no lift. Bathroom very old style with mold smell.
the staff the comfort
Kind staff, quite hotel, good breakfast,good location, fair price...


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Five circles
Print advertisment created by Café Creative, Hungary for Audi, within the category: Automotive.
More of quality.
We offer our models with extra equipment at an extremely low price.
Creative Director: Zoltan Simon
Art Director: Miklos Zsengeller
Copywriter: Gabor Szucs
Highest Rated
The day an Audi can be extra equipped at an extremely low price, it won't be an Audi.
Well those little rings there could be much better executed than copy and paste.
Nice idea
the 5th ring could leave a tyre print when joining the other fours. . . just my opinion ^^
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Our next class in the Little Rock Scripture study series will focus on the Eucharist. This study is titled "The Eucharist in Scripture." The class will emphasize the importance of meals shared in faithful fellowship as part of our covenant relationship with God. Old Testament meals and promises provide the foundation for gospel meals with Jesus, culminating in the Last Supper as understood by Paul and in Matthew, Mark and Luke. "Breaking bread" in Acts and the Bread of Life discourse in John are carefully examined.
We will be supplementing this study with the Scott Hahn book, "The Lamb's Supper: The Mass as Heaven on Earth." This book develops the relationship between the Book of Revelations and the Holy Sacrifice of the Mass.
Come join us as we learn more about the Eucharist and the Mass. Our first class will be Tuesday, October 4th from 6:30pm to 7:30pm in the Blessed Mother Room. Cost will be $20 which includes all books needed. This bible study program will meet weekly for 6 weeks. No previous experience needed. All are welcome.
Contact the parish office at 672-2848x118 to sign up.
Monthly meetings, everyone welcome!
Watch the bulletin and posters at the church entrances for
details on date and time each month.
Contact Stacy Preszler at 751-4922 with questions.


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What is Holy Week Holy Week is the week
before Easter.It includes
the religious holidays Palm
Sunday, Maundy Thursday,
and Good Friday.Not including
Easter Sunday, Easter starts
The new season of The Great
Fifty Days.It commerates the
last week of early life Jesus
When is Holy Week Holy Week is the final week
before Easter.The holidays
in the week include Palm
Sunday, Muanday Thursday,
and Good Friday.When Easter
comes on Sunday, it is the start of the Great Fifty Days. What is the beginning of
Holy Week What is Palm Sunday How is Palm Sunday Celebrated What are the events of Holy Week How is Holy Week celebrated in Spanish Speaking countries What is Easter The beginning of Holy Week is Palm Sunday.
Palm Sunday is represented as the day
Jesus walked into
Jerusalem. Palm Sunday is the
day that Jesus
walked into
Jerusalem. On Palm Sunday
Sacred music is played at churches.Also they're are plays and shows The events of Holy week are Palm Sunday,Muandy Thurday,and Good Friday, the day which he died on. Easter is known as the day Jesus rose from his grave. It was the third after his crucifixion.
In spanish speaking countries they wear speacial robes for processions. They also have different Holy Week holidays and celebrations.
How is Easter
celebrated in
Spanish Speaking countries In Spain Easter is called Semana
Santa. They have many rituals
Compare and contrast Palm Sunday the United States and Spanish Speaking countries Here we go to church and they carry palm trees to church
Compare and contrast Holy Week in the US and Spanish Speaking Countries
Here we have church sessions and there they have little festivals
Compare and Contrast Easter in the US and Spanish Speaking Countries Here we have big celebrations and they perform many old rituals.
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Semana Santa Amongst Hispanics
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Marquise Rogerson 15 April 2011
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The iPad Pro range represents the best that the iPad has to offer, from slim design to the best screens and the most powerful internal components.
Both iPad Pro versions represent the crème-de-la-crème of the tablet market, if you like. If you want the best tablets money can buy, it's probably an iPad Pro that you want as both models include features you won't get in any other device.
For a start they use ambient light sensors to detect the level of light in the environment and adjust the screen accordingly - this all works separately to the new Night Shift mode which adjusts the amount of blue light emitted by the display late at night to help your pending sleep.
And these being Pro-level tablets, both have support for the Apple Pencil stylus as well.
The very best iPad Pro 9.7 deals
The latest 9.7-inch iPad is the most expensive but also by far the best 'regular' iPad ever
If you want a regular sized iPad – that would be 9.7-inches – and you want the best there is, the iPad Pro 9.7 is your huckleberry. It's the most powerful iPad there is, sporting a stunning screen and all sorts of other clever features never before seen in an iPad. This is by no means the cheapest iPad out there, being the very latest model, but if it's the one for you you'll find the cheapest deals below!
The very best iPad Pro 12.9-inch deals
It's the biggest iPad ever and it's not cheap but there are some good deals out there
This is the iPad for you if you want something with the wow-factor. At 12.9-inches it's by far the biggest iPad Apple has ever made and it packs super powerful internal organs that turn it into a hyper productivity device. Again, this is not the cheapest iPad out there but the prices are a lot lower than they were on launch day – the best iPad Pro 12.9-inch deals can be found here:


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Continuing America's Leadership in Medical Innovation for Patients
Statement of
Margaret A. Hamburg, M.D.
Commissioner of Food and Drugs
Food and Drug Administration
Department of Health and Human Services
Before the
Committee on Health, Education, Labor and Pensions
United States Senate
March 10, 2015
Mr. Chairman and Members of the Committee, I am Dr. Margaret Hamburg, Commissioner of Food and Drugs at the Food and Drug Administration (FDA or the Agency), which is part of the Department of Health and Human Services (HHS). Thank you for the opportunity to be here today to discuss discovery and development of innovative medical products. My FDA colleagues and I appreciate the Committee's interest in advancing legislation to support our shared goal of speeding delivery of innovative, safe, and effective treatments and cures to patients who need them. We look forward to working with you on this effort.
FDA has helped make America's biomedical industry the global leader
Over the past century, remarkable biomedical discoveries have led to the development of medical products responsible for rescuing millions of patients from devastating diseases that previously had led to loss of life or severe reductions in quality of life. The evolution of modern medicine is a story of tremendous hope, learning, and achievement—and one that we all fervently wish to build upon. I am proud of the role that FDA has played in helping these discoveries become safe and effective treatments for patients.
America has long been at the forefront of biomedical discovery. Decades of taxpayer investments in biomedical research, including a focused investment in cancer research, launched in the 1970s, produced fundamental scientific advancements. Significant investments by U.S. pharmaceutical and biotechnology companies, along with the work of NIH-funded investigators across the country, have helped to translate these insights into innovative medical products for patients. FDA oversight of product approvals has built public trust in the safety and efficacy of new drugs and devices and confidence in America's biomedical industry. Major improvements in public health resulted and vital industries flourished. As FDA, Congress, and stakeholders pursue opportunities that provide the most promise for continued development, it is critical that we maintain safety and efficacy of products on which patients and physicians depend.
Public health crises led Congress to establish standards for safety and effectiveness
It is important to recognize that innovative medical products will only save lives if they work properly. As a result of strong standards for medical product approval, our citizens now depend upon FDA to ensure that the drugs and devices they rely on are safe and effective.
Concerns about the safety and effectiveness of medical products are deeply rooted in our history. In the 19th Century, enterprising traveling salesmen hawked questionable medical products. When newspapers gained widespread circulation, sellers of medical products became leading advertisers of cure-alls containing unlabeled ingredients such as alcohol and narcotics. Eventually, Congress responded by giving FDA authority to review new drugs for safety before they could be marketed.
In 1961, reports started to surface connecting thalidomide, which was widely prescribed in other countries to treat morning sickness during pregnancy, to severe birth defects. Thousands of children in Europe were born with severe birth defects. In response to the public uproar, in 1962, Congress enacted the Kefauver-Harris Amendments to the Federal Food, Drug, and Cosmetic Act (FD&C Act). Thanks to these new amendments, manufacturers had to prove that a drug was not only safe, but also effective. Approvals had to be based on sound science. Companies had to monitor safety reports that emerged in the post-market and adhere to good manufacturing practices that would lead to consistently safe products. The amendments not only benefited patients, they helped industry by raising scientific standards that ushered in today's sophisticated, science-based life sciences industry.
As we seek to accelerate medical product development, it is essential to take care to maintain those critical aspects of the FD&C Act that ensure the safety and efficacy of these products. History has shown that allowing inadequately tested drugs and devices on the market can cause significant harm to patients, both because of unexpected dangers and, in many cases, because patients may use ineffective products when effective alternatives exist.
FDA has dramatically accelerated access to innovative medical products
This past calendar year, FDA approved 51 novel drugs and biologics, the most in almost 20 years. Today, FDA's average drug review times are consistently faster than other advanced regulatory agencies around the world, providing Americans earlier access to new, innovative drugs than patients in any other country.
In achieving these outcomes, FDA has maintained its commitment to high standards to protect the public health, while also exercising regulatory flexibility in order to help promote medical product development. This flexibility, along with FDA's work to collaborate with industry, has helped reduce product development and review times. As a result, Americans are seeing more products being approved, and in many cases, they have access earlier than patients anywhere else in the world.
FDA routinely works closely with sponsors to facilitate flexible approaches to drug development. One example is FDA's engagement with sponsors to expedite drug development under the breakthrough therapy program. We have also worked with sponsors on the use of surrogate endpoints, non-traditional trial designs, and other available tools to expedite the development of products to treat both common and rare diseases. In fact, more than one-third (69) of the new drug applications approved by the Center for Drug Evaluation and Research (CDER) from 2008 through 2013 were approved on the basis of one human study and supporting evidence. This included 167 novel drugs, some with multiple indications (for a total of 184 new indications). Almost two-thirds (112) have characteristics of a flexible development program and/or engaged in one or more of FDA's expedited development programs (fast track, breakthrough, accelerated approval, priority review), without undermining or diminishing FDA's commitment to a strong safety and effectiveness standard. These many innovative and flexible approaches underscore FDA's commitment to making drugs that are shown to be safe and effective available as rapidly as possible.
Early and frequent communication between sponsors and FDA is significantly reducing overall drug development times. For instance, an analysis of 184 new drug applications approved from 2008-2013 concluded that the median clinical development time for drugs that were the subject of a Pre-IND or "early" meeting was 1.4 years faster than drugs without such meetings. Similarly, drug development was reduced by more than a year for companies that sought an End-of-Phase I meeting with FDA, compared to companies that did not request such meetings; and companies that had End-of-Phase II meetings with FDA had higher first-cycle approval rates than those that did not. This analysis includes drugs that did not qualify for an expedited development program.
For devices, FDA's Center for Devices and Radiological Health (CDRH) is focusing on improving investigational device exemption (IDE) submissions to allow earlier and more efficient clinical study enrollment for devices. CDRH has reduced, by 34 percent, the number of IDEs requiring more than two cycles to full approval. These improvements resulted in reducing by over half the median time to full-study approval. From 2011 to 2014, the median number of days to full IDE approval has decreased from 442 to only 101, cutting the time it takes to bring a new medical device to market by nearly a full year. In addition, improvements to the de novo program have resulted in a 70 percent reduction in the average total time to decision for these submissions.
As a result of these improvements, patients are able to receive important treatments sooner. Today, 76 percent of the new drugs approved by Japan, the European Union (EU) and FDA from 2009 to 2013 were approved first by FDA, according to a report released in May by the British-based Centre for Innovation in Regulatory Science. 1
In addition to earlier access to innovative products, patients are also seeing substantial numbers of new treatment options on the market. Of the 51 new molecular entities and new biological products approved by FDA in 2014, 17 new approvals are "first-in-class" therapies, which represent new approaches in the treatment of disease. The greatest number of new drugs approved for "orphan" diseases, since Congress enacted the Orphan Drug Act over 30 years ago, also was seen in 2014. These approvals represent important advances for patients who may have limited treatment options available. Among CDER's 2014 approvals are treatments for cancer, hepatitis C, and type-2 diabetes, as well. CBER approved many important biological products in 2014, including a groundbreaking vaccine for meningitis B and a vaccine to prevent certain cancers and other diseases caused by a broader range of Human Papillomaviruses.
There are even more opportunities to accelerate medical product development
While tremendous progress has been made thus far, it is important that FDA, Congress, and stakeholders continue working to promote medical product development. In order to ensure that we are promoting the development of products that work properly, it is important that advances are grounded in science. Where there are gaps in scientific understanding, stakeholders can work together to address these gaps so that the public remains confident in the safety and efficacy of products on the market and to ensure that investments in research and development are more likely to have meaningful results.
I would like to share FDA's thoughts on some of the most promising areas that we believe could truly reach our common goal of speeding delivery of innovative, safe, and effective products to American patients, focusing primarily on transformation of the early stages of drug development and increased efficiency of drug testing and manufacturing. Opportunities to achieve these priorities include: promoting precision medicine; encouraging collaboration and data sharing among scientists; incorporating patient perspectives and experiences; bridging gaps in the science of biomarkers; streamlining clinical trials; modernizing drug manufacturing; obtaining the best experts to help accelerate cures; and reducing administrative burdens and duplication.
Advancing precision medicine
Advances in a variety of fields, including genomics and systems biology, are beginning to produce highly tailored medical treatments based on unique patient characteristics. "Targeted drug development" is a growing area of drug discovery. It is the identification of patients for inclusion/exclusion either in the pivotal studies supporting approval or for the drug's use in the labeled indication based on a genetic test, biomarker, or susceptibility test (e.g., bacterial resistance, tumor genetic mutation). These treatments are specifically targeted to treat patients who are most likely to respond, or more safely receive, the medication based on specific tests. In the early 1990s, only 5 percent of FDA's new drug approvals were for targeted therapies. Twenty years later, that number had risen to a quarter of new approvals, and in 2013, approximately 45 percent of FDA's approvals were for targeted therapies.
President Obama recently announced a Precision Medicine Initiative to advance biomedical understanding by leveraging genomic advances, health information technologies, and new methods of analyzing large volumes of data. As part of that effort, FDA has been reviewing the current regulatory landscape involving next generation sequencing (NGS) as the technology moves rapidly from research to clinical practice. With NGS technology, a single test potentially can be employed to identify thousands—even millions—of genetic variants carried by a single individual. To get the dialogue started, FDA published a preliminary discussion paper in late December that posed a series of questions about how to best ensure that tests are not only accurate and reliable, but are available for patients as soon as possible. Public comment is essential, so FDA opened a public docket and held a public meeting on NGS technology on February 20, 2015. As part of the President's Precision Medicine initiative, FDA will develop a new approach for evaluating NGS technologies to facilitate the generation of knowledge about which genetic changes are important to patient care and foster innovation in genetic sequencing technology, while ensuring that the tests are accurate and reliable.
Utilizing real-world observational data
Real-world observational data provides a vital tool to monitor medical product safety and identify and further evaluate concerns. With appropriate privacy protections, leveraging large databases containing patient EHRs, disease-specific registries, and claims data has resulted in significant advances in our understanding of health and disease, provided novel and sometimes surprising insights into potential relationships between health-related factors and outcomes, and provided important product safety data. FDA is currently querying large, diverse health care data for product safety through its Sentinel Initiative and exploring opportunities to expand the use of real-world observational data to optimize the performance of medical products.
Although there is reason to believe that in the appropriate setting these data may be helpful in providing information on the effectiveness of marketed products, such as for new uses of approved products to support label expansion, many experts in the field agree that more work is needed to make these data operational for and directly applicable to regulatory purposes. We should move quickly to further develop methodologies needed to better understand and harness the promise of real-world observational data for regulatory purposes.
Incorporating patient perspectives
Patients are uniquely positioned to inform medical product development with firsthand experience gained from living with a disease, including their use of available therapies to treat their conditions. In Prescription Drug User Fee Act (PDUFA) V, FDA committed to a more systematic and expansive approach to obtaining patient perspectives through a Patient-Focused Drug Development Initiative. FDA has, so far, held 11 public meetings on specific disease areas and gleaned much valuable insight from patients. Important patient-focused work is also already underway through the Medical Device Innovation Consortium (MDIC). MDIC is developing a framework for incorporating patient preferences into the device development and assessment process, and compiling a catalog of methods for collecting patient-preference information that can be used to develop, design, and market devices that meet the needs of patients. One recent example, highlighting the impact of patient perspectives, was the decision to approve a device to treat obesity. The decision to approve the device was based in part on the data from a study that showed a substantial portion of obese patients would accept the risks associated with a surgically implanted device, if they lost a sufficient number of pounds.
We believe that more can be learned and applied by engaging in a transparent, multi-stakeholder approach, potentially through public-private partnerships, that identifies sound and rigorous methods to capture science-based, disease-specific patient input in an analytically meaningful and useful form that can be incorporated directly into drug and medical device development and review processes. This should include capturing information on the natural history of diseases, including identifying and measuring aspects that matter most to patients. Developing guidance to enable patient groups to become active participants in this process and to help industry incorporate appropriate methods in drug development programs also will move the field forward.
Bridging gaps in the science of biomarkers
FDA believes that accelerating the development of reliable biomarkers is essential to advancing important new therapies. FDA already accepts the use of hundreds of biomarkers for a variety of purposes throughout drug development, such as proof-of-concept, diagnosis of disease, enrichment of trials with patients most likely to respond, and as surrogate endpoints that can support accelerated or traditional drug approval. For example, 45 percent of drugs were approved by FDA on the basis of a surrogate endpoint between 2010 and 2012. There remain, however, many diseases such as Alzheimer's disease for which disease-specific biomarkers have not yet been developed, or shown to be reliable for use in the regulatory review process. When we do not understand the disease pathways, biomarkers appearing to be linked to disease progression can fail because they are not, in fact, in the causal pathway for the disease. A wide range of stakeholders is necessary to achieve meaningful progress in developing additional biomarkers that can be used by the scientific community. Important work is already underway through the National Institutes of Health (NIH), the Biomarkers Consortium in which FDA participates, and the Critical Path Institute.
The principal barrier to biomarker development is the lack of scientific understanding about the causes and biochemical pathways of many diseases. Continued public and private investment in biomedical research is key to filling this knowledge gap and to improving understanding of how to show whether a biomarker is clinically meaningful. Collaboration among NIH, FDA, academia, industry, and patient groups can lead to development of standards of evidence for using biomarkers for regulatory decisions.
Leveraging clinical trial networks
The time and expense associated with designing and conducting clinical trials is one of the most significant limiting factors to drug and device development. Widespread use of clinical trial networks and master protocols could dramatically improve clinical trial efficiency—and create a new drug and device development paradigm that benefits both patients and industry. The recently initiated Lung Cancer Master Protocol (Lung-MAP) is an excellent example. A master protocol creates a single clinical trial infrastructure to test many drugs at the same time. In the case of Lung-MAP, patients are assigned to one of five different drugs being simultaneously tested, based on the results of genomic profiling to screen for alterations in more than 200 cancer-related genes. Additional drugs can be added, or dropped, as appropriate, over time. FDA is highly supportive of the use of master protocols, and we are working with key stakeholders to advance their use.
Modernizing drug manufacturing
Advances in pharmaceutical manufacturing technology provide new opportunities to lower costs, limit drug shortages, and reduce supply chain vulnerabilities—and reinvigorate U.S. pharmaceutical manufacturing. A promising example is the new technology that enables forms of "continuous manufacturing" to produce a finished drug product in a continuous stream, as opposed to traditional methods that involve a series of sequential and discrete "unit operations," such as milling, mixing, and granulation. Unlike traditional manufacturing, which can take close to a year from start to finish, continuous manufacturing could take only a few days, increase equipment utilization rates up to 95 percent, and dramatically reduce the risk of production failure and negative environmental impacts. Continuous manufacturing could also reduce the likelihood of drug shortages. FDA has been working for over a decade to stimulate modernization of U.S. drug manufacturing, but more work is needed, including supporting academic research in this area and expanding opportunities for collaboration, possibly through public-private partnerships or consortia.
Hiring and retaining highly qualified experts
In order to achieve its mission in a complex, global, and rapidly evolving scientific arena, FDA and industry agree: the Agency must be able to attract, recruit, and retain talented leaders, physicians, scientists, and other experts to effectively review cutting-edge products and conduct post-market surveillance activities. Delays in bringing selected candidates on board may prompt highly qualified experts to pursue opportunities elsewhere.
Allowing use of central Institutional Review Boards (IRB)
The FD&C Act mandates review of a clinical trial on a device by a "local" IRB, or by FDA in rare circumstances, although there is no comparable requirement for drug trials. This can require review of multi-site studies by many different IRBs, and each IRB may require the study sponsor to meet different, sometimes inconsistent requirements for study approval, increasing the length and cost of trials. Studies have shown that the use of a central IRB for multi-site drug studies can significantly improve efficiency, without undermining trial participants' protections. A modification of the FD&C Act to bring IRB review of device studies in line with drug studies would accomplish the goal of greater efficiency, without sacrificing oversight.
I am incredibly proud of the progress that FDA has made during my tenure to speed medical products to patients. I look forward to working with Congress to accelerate product development more while continuing to ensure that American families can rely on the safety and effectiveness of products on the market.
1. "New Drug Approvals in ICH Countries, 2004-2013," Centre for Innovation in Regulatory Science, R&D Briefing 54, 2014.


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ok no more cheesing.
It is so nice to feel good in my normal clothes again. Every month my body goes back to normal a little bit more! To any of you readers trying to lose baby weight and get back in shape, be patient! Work hard and it will happen! My baby is almost 5 months old and despite working my butt off, my body is still not back to normal.
top and cardo-target
necklace-Charlotte russe


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Ryu's bag
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I almost bought a bag that looked almost exactly like this for an 18th century period costume. The guy told me what it was called, but I can't remember. It was something along the lines of "sailor's sack" but that isn't it. Sailors used sacks similar to this for hundreds of years. They're very simple and made from heavy linen or canvas; heavy muslin also works. I checked a bunch of reenactment supply sites and tried a number of search terms but had no luck (which is really kinda bugging me >_<).
Fortunately, they're pretty easy to sew up. In fact, my first sewing project in 7th grade home economics was pretty similar to this. You sew a piece of fabric into a cylinder. You sew a circle of fabric onto the base. You sew up a shorter cylinder of fabric as reinforcement, and sew a 2nd circle onto that, optionally rolling a cord into the seam so it holds it's shape tighter. You turn both pieces inside out so the seams are all hiding. you fold the top edge of the reinforcing piece inward and top-stitch it onto the sack so that it looks like the picture. You can optionally tuck cord into that fold too. You then either fold the top of the sack inwards and hem it up so it looks like your picture, or more sensibly, you fold the rope into the hem before sewing it (being careful not to sew through the rope) and now you've got a proper drawstring.
For the tie-off string, use proper hemp rope if you can find it (not easy in the US), else use cotton rope. The rustic looking jute rope at the hardware store is incredibly uncomfortable to carry around.
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IBEX 2013: Exhibitor Video Awards winners announcedPosted on
The International BoatBuilders Exhibition & Conference announced the winners of the second annual Exhibitor Video Awards on Monday at the Industry Breakfast at the Kentucky Exposition Center.
SeaStar Solutions (formerly Teleflex Marine) won the Best Product Video for Optimus 360 by SeaStar Solutions and Best Company Video for Teleflex Marine Is Now SeaStar Solutions.
The Peoples Choice Award went to Dometic Corp. for its video titled Dometic Spot Zero Dock Box Hose Down Your Boat and Let It Air Dry.
A panel of judges from the Marine Marketers of America selected the best product and company videos. The most votes on the IBEX Facebook page determined the Peoples Choice award. The video awards competition was open to all 2013 exhibitors that posted a product or company video with their online booths on the IBEX website.
Video content is cheaper than ever to implement and really adds a wow component to your campaign, John Chiles, one of the MMA judges and owner of Engaged, a marine industry social media manager, said in a statement. Videos really put a face on your brand, and set you apart from the crowd. If a picture is worth a thousand words, then a video is worth ten thousand.


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Question: Consider the following diagram of free energy G versus fraction
Consider the following diagram of free energy (G) versus fraction of A reacted in terms of moles for the reaction 2A(g) → B(g).
View Solution:
Before any A has reacted, PA = 3.0 atm and PB = 0. determine the sign of ΔGo and the value of K for this reaction.
View Solution:
Answer to relevant QuestionsCalculate ΔGo for H2O(g) + 12 O2(g) ⇌ H2O2(g) at 600. K, using the following data: H2(g) + O2(g) ⇌ H2O2(g) K = 2.3 × 106 at 600. K 2H2(g) + O2(g) ⇌ 2H2O(g) K = 1.8 × 1037 at 600. K Consider the relationship The equilibrium constant for some hypothetical process was determined as a function of temperature (in kelvins) with the results plotted below. From the plot, determine the values of ΔHo and ΔSo ...Consider 1.00 mole of CO2(g) at 300. K and 5.00 atm. The gas expands until the final pressure is 1.00 atm. For each of the following conditions describing the expansion, calculate q, w, and ΔE. Cp for CO2 is 37.1 J K-1 ...Many biochemical reactions that occur in cells require relatively high concentrations of potassium ion (K+). The concentration of K+ in muscle cells is about 0.15 M. The concentration of K+ in blood plasma is about 0.0050 ...The standard entropy values (So) for H2O(l) and H2O(g) are 70. JK-1mol-1 and 189 JK-1mol-1, respectively. Calculate the ratio of Vg to Vl for water using Boltzmann's equation. (See Exercise 22.)
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Latest content added for Digital Library Partner: UNT College of Visual Arts + Designhttps://digital.library.unt.edu/explore/partners/UNTCVA/browse/?fq=str_location_country:Germany&fq=untl_decade:1950-1959&fq=untl_collection:TXFC2014-09-26T09:40:06-05:00UNT LibrariesThis is a custom feed for browsing Digital Library Partner: UNT College of Visual Arts + DesignBreton Hat2014-09-26T09:40:06-05:00https://digital.library.unt.edu/ark:/67531/metadc402574/

Breton hat of beige fur felt. The domed crown of beige fur felt is divided in two along a line from front left to back right, the split edged in a dark beige/light brown vinyl band, with a mushroom-shaped vinyl-covered shape at the top. The wide brim curves up and around the crown, and is lined/faced with the same fur felt, while the part of the brim facing the crown is lined in beige fabric. The crown is unlined, with a beige grosgrain ribbon inner hatband. Designer's label inside: "Styled by / Coralie" Stamped inside crown, mark of maker of felt body: "Empress / Body made in Western Germany"
Toque2014-09-26T09:40:06-05:00https://digital.library.unt.edu/ark:/67531/metadc402539/

Toque of black fur. Base of crown decorated with black felt that creates loops half the height of the crown. Unlined with black grosgrain ribbon headband. Label on inside of band: "VOLK" Stamped on inside top: "Empress / Body made in Western Germany"
Gloves2012-07-02T22:15:28-05:00https://digital.library.unt.edu/ark:/67531/metadc87016/

Pair of gloves of white cotton. The plain, daytime gloves are wrist-length. Retailer's label sewn inside: "Made in Western Germany / expressly for / Neiman-Marcus / 100% Cotton"


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Wes Craven's 'Summer of Fear' Makes its Blu-ray Debut This October
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text: 19 photos $839,000 93 acres Co Rd 18, Hodges, AL 35571 - Marion County 93 acres Hodges, AL PENDING! Carter Poultry is a 3 house broiler poultry farm on 93+/- Acres of pasture and wooded land located outside of Hodges, AL. The 3 houses 54500 and were built in 2009. The farm is currently growing for Pilgrims Pride in the Russellville Complex growing a 10 lb bird. MarJac also operates in the area of this farm. These are well-maintained houses with Rotem Platinum Plus controlers, Radiant tube heat, ChoreTime feedlines, and Val-Co drinkers. In 2015 the seller spent $98,000 on updates on the houses to include adding nylon drops, rework all main cables, new Val-Co drinkers, new Choretime feeders, and adding 1 48 fan and 2 56 fans to each house. The land is gently rolling with about 20 acres in open hayfields and the remainder is w Robert King Jr. Southeastern Land Group, Inc


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A place in , Changi is an interesting place to visit, given its unique culture, history and character. Changi is located at a short trip away from Amritsar a major city in . So, ideally any vacation planner would recommend you to visit Amritsar for its bountiful attractions like The Golden Temple, Jallianwala Bagh, Wagah Border on your trip to Changi. A vacation to Changi can typically be of 1-2 days. Immerse in the spirit of the city and you'll not miss your home.
Get, set and plan a journey with this amazing travel planner for Changi that shall leave you with plenty of memories at the end of your trip.
Explore the best journey planner for your visit to Changi and create a flawless plan in few simple steps!


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In Australia, iPhone 5S More Popular
Australia headed the queue of countries launching Apple Inc.'s new iPhone 5S and 5C Friday, although interest among the hundreds of tech fans who camped out overnight centered mainly on the high-end smartphone.
And in a sign the products haven't created the same buzz as Apple's previous launches, the first customers showed up 20 hours before 5S and 5C went on sale at the U.S. company's flagship store on George Street—one of Sydney's busy arteries. That was well down from a year earlier when the launch of the iPhone 5 tempted Aussies to queue for nearly three days in advance.
Still, Jimmy Gunawan said it was worth the wait. The 33-year-old 3D animator claims to be the first person in the world to purchase an iPhone 5S, sacrificing a night's sleep to ensure he was first in a line that ultimately stretched around 150 meters round the block.


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|First appearance
|18th June 1986
|Number of appearances
|Played by
|Stephen Crane
The Policeman was the first officer on the scene when fire broke out in the Rovers Return Inn in June 1986 as a result of faulty wiring in the fuse box carried out by Jack Duckworth.
His main duties were keeping the residents back to enable the firemen to carry out the task of rescuing Bet Lynch and putting out the flames. He had no chance of keeping the crowds back when Kevin Webster, who had attempted to rescue Bet, was himself brought out and attended to by the ambulance crew and was duly accorded a hero's welcome.


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Description: Current and comprehensive and designed to maximize clarity of the concepts you need to know, longtime best seller ADVANCED NUTRITION AND HUMAN METABOLISM, 5e, delivers its signature quality content in a more student-friendly presentation. With a striking new design, this respected market leader is more accessible, with relevant examples, illustrations, applications, tables, and figures to emphasize key concepts. This text continues to set the standard through the authors' ability to clearly and accurately explain even the most complex metabolic processes and concepts. The authors have updated the art for this edition with easier-to-understand captions that illuminate the processes being shown. It's the only book written for undergraduates that consistently stays at that level. Providing thorough and detailed coverage, the text equips you with a solid understanding of digestion, absorption, and metabolism of fat, protein, and carbohydrates. It covers the biochemistry of vitamins, minerals, and energy nutrients. It also examines the structure and function of water-soluble and fat-soluble vitamins and their regulatory role in metabolism, looks at electrolyte and fluid balance, and covers the role of nutrition in the development or exacerbation of chronic disease. With ADVANCED NUTRITION AND HUMAN METABOLISM, 5e, you are well prepared as you continue your journey in the field of nutrition.
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List price: $286.95Edition: 5thCopyright year: 2009Publisher: WadsworthPublication date: 2/14/2008Binding: HardcoverPages: 624Size: 9.00" wide x 11.25" long x 1.12" tall Weight: 3.520Language: English
Dennis G. Zill is professor of mathematics at Loyola Marymount University. His interests are in applied mathematics, special functions, and integral transforms. Dr. Zill received his Ph.D. in applied mathematics and his M.S. from Iowa State University in 1967 and 1964, respectively. He received his B.A. from St. Mary's in Winona, Minnesota, in 1962. Dr. Zill also is former chair of the Mathematics Department at Loyola Marymount University. He is the author or co-author of 13 mathematics texts.Sareen Gropper is a professor and graduate program director at the Department of Nutrition, Dietetics, and Hospitality Management at Auburn University. She is an expert in the area of infant feeding and lactation.
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BP, VERC and Love's Donate
Companies raise money for Children's Miracle Network and educational institutions.
OKLAHOMA CITY -- Charity continues in the convenience store industry, as Love's Travel Stops & Country Stores, BP and VERC recently completed various donations.
Love's, based here, raised $760,000 during its annual fundraiser for Children's Miracle Network, an increase of 84 percent from $415,000 in 2007 and the highest total in the 10-year history of the campaign, the company reported.
Since beginning its affiliation with Children's Miracle Network in 1998, Love's and its customers have raised more than $2.5 million to help sick children in the communities where it operates stores.
"In spite of the current economic climate, our employees and customers managed to raise a record amount for Children's Miracle Network," said Tom Love, founder and chairman of Love's. "We are proud that their efforts will help provide state-of-the art medical care to seriously ill children across the country."
Each September, Love's invites its customers to help raise funds for Children's Miracle Network through in-store purchases of paper heart icons valued at $1, $5 and $25. Love's stores raised additional funds through grassroots activities such as car washes, bake sales, and pumping gas for tips.
In addition to the money raised by Love's customers and employees, the Love family marked the 10th anniversary of its affiliation with Children's Miracle Network by donating $50,000 to the campaign. The donation was made Sept. 4, at the grand opening of the newest Love's location in Oklahoma City.
Additionally, Walter Neil, director for public relations for BP Carson Refinery, presented a check in the amount of $50,000 to California State University, Dominguez Hills (CSUDH) to create the BP Scholarship, the company reported.
The donation was made during the College of Business Administration and Public Policy's annual awards luncheon, at which BP was honored as Organization of the Year.
In presenting the check, Neil talked of BP's strong support of CSU Dominguez Hills and its mission to educate the local community. The check represents a continuation of that commitment, he said.
The $50,000 BP Scholarship will provide five $2,000 scholarships annually over a five-year period to first-time freshman or community college transfer students living in Carson, Long Beach or Wilmington who seek degrees in either chemistry, physics, mathematics, business administration or environmental sciences. The first scholarships will be awarded for fall 2009.
In other charity news, VERC Enterprises presented the South River Elementary School in Marshfield with a check for $500, a grant made possible through the Mobil Educational Alliance Program, the company said.
Presenting the check to South River Principal Linda Loiselle and Student Council members Jenny Vo and Sean Callahan were Anna Cononico, VERC District Manager and Shan Muhammad, manager of the VERC Mobil Pembroke.
The $500 grant will be used for the enhancement or purchase of math and science programs and materials.
Since 2000, the Mobil Educational Alliance Program has contributed more than $13 million to local schools through its retailers.
"We're proud to participate in such a fine program that recognizes and supports the quality of local schools," said Leo Vercollone, CEO of VERC Enterprises.


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Tangled Hair
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9:00 am - 5:30 pm
After trying a few salons this would have to be my favourite. Not only are they well priced but they also have great staff. They have great recommendations for what would suit you best and even better the amazing staff remember you by name. Wont go anywhere else. #reviewtowin
I did not have my hair done at this salon as I was unhappy with the phone service I received. After receiving a bad haircut and colour from another salon, I rang Tangled Hair and politely asked, "I have a hair disaster and am wondering if you could help me?" The hairdresser on the phone replied in a rude and blunt way, "Yeah, what?" I explained the situation, and they abruptly said that it would take three visits (with a full head of foils each time) to fix my hair, however they ...read more
sorry i disagree this salon ha to be the best in penrith the ladies did a wonderful job very happy with results !!!!!!
This has to be the worst experience came in for a wash cut blowdry last week and i asked for a flicks and the staff started washing and was not a satisfying feeling , shampoo was left underneath my hair and the hair felt dirty still ! water down my back as i left the chair i thought staff was going to start cutting i think another stylist came took over and gave ...read more
Worst hair experience ever! Salon had horrible lighting & my consultation was rushed. Whilst getting shampooed at the basin the staffs whispered about me & made some nasty comments about my hair. They were extremely rough when milking my colour through my head was literally tilted back & they burnt my scalp the entire time during the blowdry. I wanted to go from brown to violet & I didn't notice until I got home (due to their horrible lighting) that my roots ...read more


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Few open wounds after Labiaplasty (5 days P/O). Will this heal and close without being re-stitched? (Photo)
Doctor Answers 3
Labiaplasty healing
A bleed can put pressure on any incision and especially with a weaker incision like the wedge, this can happen. Keep the area clean and allow it to heal . Once healed in a few months, if there are asymmetries, a revision can be performed. You may be a candidate for sutureless labiaplasty revision in the future, depending on the final outcome after healing.
Another wedge labiaplasty falls apart
Learn more: http://www.lvr-nj.com
Open of labiaplasty
The information above should not be considered a substitute for consultation with a board-certified plastic surgeon to address individual medical needs. Your particular facts and circumstances will determine the plastic surgery treatment which is most appropriate for you.
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These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


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Director of Operations
John Peaden
John Peaden began his career with HM Land Registry at our Durham office in 1977 at 19 years of age. Over the years he has worked in our Tunbridge Wells, Stevenage and Harrow offices. John took up his role on the Board in April 2010 and is also the HM Land Registry Board Champion for issues relating to gender. His previous roles include:
- Area (Operational) Manager
- Head of Computer Implementation and Development
- Middle manager (efficiency and process improvement)
- Caseworker
Director of Operations
The Director of Operations is responsible for managing and developing key performance indicators (KPIs) that relate to the way we operate as an organisation.
Previous roles in government
Chief Executive and Chief Land Registrar
- 2015 to 2015
Director of Operations
- 2010 to 2015


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Order now to get it by: Monday August 07 - Wednesday August 09
This product ships with limited tracking information, and may take longer than usual to be delivered.
Condition: New
Product ID: 198527
Delivery Information |Returns & Exchanges |Payment Methods
Engineered with a youth player in mind. The smaller sized backpack has padded back and straps for ultimate comfort and
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Let us know when your receive great advice so we can thank our lawyers and point others with similar questions in the right direction.Got it!
The statement reads, "Dr. XX shall take no action to directly or indirectly solicit or otherwise encourage or entice any current client of the Hospital to remove their business from the Hospital for a period one year from Closing". I have a Facebook page and website for the new business. If former clients contact me via the FB page or website contact information am I in breach of the contract if I then do business with them? I am not offering any discounts or special offers for former clients. I am unclear as to the legal definition of this phrase.
The word "indirectly" in that non-compete clause carries a lot of meaning. Violating a non-compete can have significant and long-term consequences. You should be very careful to not give the hospital any reason to pursue claims that you have violated the non-compete provisions. That said, it is also important what the remedy clauses in the contract state are the available remedies for the hospital if you do violate the non-compete clause.
It would be in your best interest to seek formal advice of counsel about what actions - direct or indirect - you may be able to take, and more importantly about the possibility of renegotiating the non-compete provisions with the hospital.
If you have further questions, you should contact an experienced attorney for a consultation. Remember, unilateral contact of an attorney through a law firm website, by email or any other written correspondence or telephone DOES NOT create an attorney-client relationship or establish confidentiality or privilege. Also, remember, this is a public forum and anything posted here is not privileged or confidential, so do not post more specific information here or send more specific information to any attorney be email unless specifically requested by the attorney after you have entered an attorney-client relationship by you and the attorney signing a representation agreement. Contact a local attorney for a confidential and privileged consultation, during which you can inquire about and if you elect establish an attorney-client relationship.
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Good Luck!
I invite you to use the links available on this page to locate my avvo.com profile and CONTACT ME AT MY OFFICE for a personal consultation, because the information provided in the above answer is not legal advice, nor is it intended to be legal advice. It is general information that is incomplete and may not specifically apply to your particular circumstances, so you should not act upon it until discussing your situation with an Arizona attorney. Every case is unique. Most legal principles have important exceptions that may apply in your case. You should actually talk to an Arizona lawyer regarding your situation before taking any action or declining to take action. As mentioned above, I invite you to contact my office, but please note that contacting my office in any way, submitting your question on this site, my general response above, and any further communication whether electronically, by letter, or by telephone, does not create an attorney/client relationship. You will know when my office represents you because you will have received a signed representation agreement. Please do not send or communicate any confidential information until you receive a signed representation agreement with an attorney.Ask a similar question
The way the covenant is worded, I don't think you're in breach. However, because the hospital is not likely to believe you that you did nothing to attract those clients, you may be headed for litigation. Your defense, if so, will depend on the testimony of the transferring clients.Ask a similar question
I would recommend you take some time, gather current copies of all information in your new website and facebook page for the business and then meet with an experienced attorney. Non-competes and non-compete provisions can be somewhat difficult to enforce in Arizona, especially against doctors. This does not mean that you are not violating the provision there is no real way to answer that question without additional information; however, it is difficult to envision a scenario where the presence of a website or facebook page about a new business is going to be considered solicitation. Good luck.
This information is provided for general informational purposes and is not intended as legal advice. An attorney licensed in your jurisdiction can answer questions specific to your specific fact situation and provide you appropriate advice as necessary based on the specific facts of your matter and the jurisdiction in which you reside. If you are in Arizona and interested in discussing your matter further I can be reached at: (480) 838-9000 Mark D. Fullerton, P.C. 1839 S. Alma School Road, Suite 275 Mesa, Arizona 85210Ask a similar question
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Slow-cooked flavors in 45 minutes or less
Slow-cooked flavors in 45 minutes or less
How does celebrity chef Tyler Florence juggle a booming empire and family life? With fast, flavorful recipes like this tasty seafood stew.
Recipe: Halibut, Clams, and Pancetta with Escarole
This dish, using canned hominy, takes a fraction of the time needed for regular posole. Serve with warm corn tortillas.
Recipe: Spicy Chicken Posole with Avocado and Lime
Chinese five-spice powder infuses this colorful stew with a warm, anise-y note.
Recipe: Chinese-style Beef, Sweet Potato, and Bok Choy Stew
This hearty, less-is-more stew riffs on rustic Italian flavors. Serve with crusty bread and a green salad.
Recipe: Escarole and Cannellini Bean Stew
Think of this as a fresher, green-herb-laced version of the French classic. Serve with a crusty baguette for dunking.
Recipe: White Wine Coq Au Vin
Wild rice gives this stew earthiness and is appealingly chewy (save time by buying it precooked). Serve with cornbread or polenta.
Recipe: Wild Rice, Butternut Squash, and Cannellini Stew
The addition of chipotle purée imparts a rich, 'tastes like it's been simmering for hours' flavor in this dish, which actually comes together in just about 30 minutes.
Recipe: Black Bean Chili
Light coconut milk in this stew works as a healthy alternative to the full-fat kind, and prepared Thai red curry paste, found in most supermarkets, makes it a snap to put together.
Recipe: Thai Red Curry Fish Stew
Boned, skinned chicken thighs are just as convenient as breasts, and they have an added advantage: Their succulent texture and robust flavor stand up well to braising.
Add the flavors of Italian salsa verde--bright parsley, tart lemon, piquant capers, and green olives--for a fresh, fast twist on cold-weather cooking.
Recipe: Chicken Stew with Olives and Lemon
This dish provides a meal's worth of protein, carbohydrates, and vegetables (plus a lot of fiber), so all you need on the side is a crisp green salad.
Recipe: Spicy Lentil Stew with Peppers and Onions
Any mix of seafood works well in this chewy-tender stew, which pairs beautifully atop nutritious quinoa.
Recipe: Spicy Seafood Stew
Spicy sausage, sweet potato, and saffron lend an exotic touch to this otherwise simple chowder.
Recipe: Halibut and Sweet Potato Chowder
This fragrant, buttery stew is hearty enough to work as a vegetarian main dish. Serve with a green salad and naan (Indian flatbread) or fresh pita.
Recipe: Split Pea-Squash Stew with Basil and Serrano
This Italian-style stew features vegetables from Spring's bounty, but replace fresh peas and artichokes with frozen and it's a simple dish to prepare year-round.
Recipe: Rustic Spring Vegetable Stew
This filling meal comes together fast, thanks in part to the ease of using canned beans, which are already soft and ready to go.
Recipe: Warm Tomato and White Bean Stew
Coconut milk smoothes out the assertive Chinese five-spice blend in this quick chicken dish.
Recipe: Singapore Chicken Stew
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text: Sorting type: Most visited Most visited Alphabetical | Pages in category "Writers" Rob McElhenney Charlie Day Glenn Howerton David Hornsby Chris Romano & Eric Falconer Retrieved from "http://itsalwayssunny.wikia.com/wiki/Category:Writers?oldid=6079" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Crew Add category Cancel Save


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Amazon Kindle Unlimited is now accessible in Japan – Good e-Reader – Good E
August 3, 2016 - Kindle Unlimited
Amazon Kindle Unlimited has only launched in Japan. The module costs ¥980 per users will get entrance to over 120,000 Japanese titles and over 1.2 million titles in other languages.
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MICROTEK has been producing innovative scanning solutions for over two decades, and still continues to make technology breakthroughs in scanning solutions.
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You get CCD image quality with a cold cathode lamp that can't go the distance, like any cold cathode (fluorescent) lamp it starts to wear out from the outer edges.Other scanners use CIS (Fax type) sensors and LED lights but CIS doesn't have the depth of field or sensitivity of CCD.
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Combine the flavor of mesquite briquets and the ease of Match Light® charcoal and you are on your way to a successful BBQ.
The mesquite wood in the Match Light® with Mesquite briquet means more of that smoky mesquite taste in your favorite barbecued foods. That's because each briquet contains high quality mesquite wood that smokes while burning to infuse your food with an unbeatable smoky taste.
With Sure Fire Grooves® and just the right amount of lighter fluid added Match Light® with Mesquite charcoal makes for Easy Lighting. Just light the briquets in one easy step and you'll be ready to cook in about 10 minutes.


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Admire the most beautiful places of Alfonsine and add them to your basket. YAMGU will create your trip considering distances, opening hours and weather.
Already in 1928, on the occasion of the first Centenary of the death of the poet Vincenzo Monti (1754-1828), main exponent of neoclassicism in Italian 18th-century his birthplace had constituted the first nucleus of montiano Museum, which opened its doors completely recovered and renovated in 1998. Become the property of the municipality of Alfonsine in 1957, on donation of Cassian, Mahoney still retains part of the original furniture, furniture, paintings, prints, furniture and various personal items of the literate. There are numerous testimonies of biographical poet, including a manuscript
The Museum is housed inside the Cultural Centre, together with the municipal library and the historical Institute of the contemporary age and Strength of the province of Ravenna. It was founded in 1981 by the municipality of Ravenna, in collaboration with the province of Ravenna and the Emilia-Romagna region, and with the support of the nine municipalities of the Valle del Senio and Historical Office staff Italian army especially to collect and preserve memories and documents the events of the years 1944-45 in Romagna. Important strategic objective, Alfonsine was liberated by combat "Cremona",


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text: My husband and I are having another child and since I named our first son Jackson Dean Lee and not saying he doesn't like his name but he just left it up to me the first time!!! We have agreed that he can name the second child..he wants Bayleigh for a girl and Bently for a boy...I LOVE unique ways to spell names...(of course can't you tell by JACKSON'S name OhHhHh so simple LOL) but something that people will know..the name. AND something a MAN can spell without questioning everytime.


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Posted by anonymous
Mr. Scharf was straightforward with me about how he thought my divorce and alimony would end up from our first meeting. I felt that he gave me great advice and educated me on how the process worked. Even though I did not agree on how the system decides alimony, I knew in advance what to expect at our mediation. Mr. Scharf was able to settle my divorce with no surprises. On many occasions I got frustrated with the process of my divorce but Mr. Scharf eased my mind. He has a great knack for dealing with people. I could tell that when we walked through the court house together, he was well know and respected by the judges and other lawyers. I am confident he did the best possible job for me.
Posted by anonymous
He gave me good advice on how to handle my paternity action and would spend time talking to me as a regular person. He did not treat me like I was just a client but has a nice personal touch. He was always responsive to phone calls and my case ended in my favor.


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Piss Japan TV
On The Road Again
In a taxi, from Hell, this boy's not about to stop for a PissJapanTV.com model. Getting creative, she pulls out a bag and flashes what fine objective she has. As she empties her bladder, and fills the bag, they fountain along. Wiping her lips, she twists and trusses up the sack; no need to stop, she just had to geyser. Waking from a nap, our next female's not alone, but she's on the only one that has to go. Jiggling around, she asks if the taxi driver would pull over; that's a no. With no other choice, she grasps a bag, cowers and takes off her undies. Doing her greatest not to splatter in the car, she explosions up the sack with her yellow water. Done, the driver now pulls over to let her make a deposit.10564 Views
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08 October, 2016 by Anonymous:
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Blogs // 1 Articles
Media // 1 Articles
A Winged Victory for the Sullen: Atomos
4 Jan 2015 // 9:04 PM
The duo's impeccable, immovable second album was conceived as an original score for a dance performance.
A Winged Victory for the Sullen - Minuet for a Cheap Piano #2
28 Oct 2011 // 2:30 AM
One thing's for sure, A Winged Victory for the Sullen won't make you angry or want to destroy civilization. Which is more than can be said for Cobra Starship.


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When & Where The Camden Crawl London Festival occurs on the May Bank Holiday in in Camden, London England.
What to expect Hundreds of gigs and performances from the today's best indy artists from Amy Winehouse to Travis. During the "down time" there's lots of stand up comedy shows, street performers, short films, busking, bingo, poetry, magic sows, theatre and workshops.
Getting there Book a flight into any of Londons airports available here or get to Camden by train here.
Previous Performers Akala Art Vs. Science Autokratz Best Coast Billy Childish Billy Vincent Bo Ningen Calvin Harris Cornershop Dead Meadow Graffiti 6 Holly Miranda Housse De Racket I Blame Coco Jamie Woon Karaoke For Beginners Kasms Left With Pictures Let's Go To War
Things change, always check details with a second source. We do not guarantee the validity of information found here and on associated websites and therefore can not be held liable. www.FestivalPig.com © All Rights Reserved 2007-2015.


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Train to Busan Movie Review :
Train to Busan Hindi Dubbed Full Movie Watch Online Download Free
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…the contributions to my institution across Education, Research and Professional practice all involve Black British Academics to a large extent.
This is what social justice pedagogy looks like – my students in BBC Radio Solent interview
I need to share my sense of pride in my final year students on a unit I developed at Bournemouth University (BU) called Media Inequality.
So proud: my final year student wins award for best dissertation paper
At the end of the conference when award winners were announced, I was proud and very happy for Doyin, who was announced as winner of the award for Best Overall Paper.
Race debates to conclude at London College of Fashion
London College of Fashion (LCF) is to host the final discussion around race equality in creative higher education and creative practice on March 7, bringing to a close the series of college debates organised by Shades of Noir. The debates aimed to stimulate broad
Shades of Noir breaks new academic ground in the arts
Amid the furore surrounding London Metropolitan University over the revocation of their licence to teach non-EU students which has cast a somewhat gloomy cloud over the HE sector; the launch of a major exhibition to showcase the work of high-achieving black


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For all Australian deliveries you will get a email notifications direct from Aus Post to let you know where your parcel is at.
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The remaining countries we receive a parcel ID number and can only track if we are concerned that the parcel is lost. Please contact us asap if you have not received your parcel within the time frame above and we will help you to track it down.
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No you don't. Your order will either be left on your doorstep or in your letter box. We do recommend that your order be sent to your work address or to someone you know that will be home to keep it nice and safe. As we can not accept responsibility for orders stolen once delivered.
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We pretty much can send your Lyloh order to pretty much anywhere in the world. Except for Antartica only because I don't think they have a postal service ;)
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