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It took
Hooper had just spent "the worst year of my life" as the chief financial officer at paper merchant
"It was hard to know if there was anyone else in the frame," says the silver-haired 53-year-old. "But within a week we had agreed around the principles of me coming back. I sat down with then chairman
In the past 18 months, Hooper has reshaped Sigma, sold its distressed generic drug manufacturing operations to South Africa's Aspen Pharmacare in a $900 million deal, cut costs, tightened inventory and reined in working capital.
After two years of hefty losses, Sigma posted a $26.7 million net profit in the first half of 2012. Underlying earnings before interest and tax of $35 million beat some analysts' estimates. The stock, although a far cry from its five-year high of $2.87, has climbed 38 per cent over the past 12 months to 60.5¢.
Hooper says it was a difficult three months between announcing his departure as CFO of the troubled PaperlinX and stepping up to the CEO role at Sigma, which seemed just as troubled.
"It was hard because I was CEO in waiting and there is nothing I could do," he says. "I sort of had to manage that from a distance. It was possible that Aspen might have proceeded with a full takeover of the business."
Hooper started his career at BHP Billiton and spent 20 years in the resources sector before trading diamonds for jelly beans, joining Sigma where he was CFO from 2001 to 2006.
He says he left Ashton Mining when Rio Tinto bought the business because he didn't want to get "typecast as a resources guy forever".
Hooper took over from Elmo De Alwis in September 2010, working hard to get the company back on track as it wavered under a $900 million-odd debt and breached its covenants. He felt Sigma was a business he could try to fix.
"I felt like I knew the business," he says. "On one hand I worked there before but the fact that I had not been in the business for a while gave me an advantage to see what was wrong from the outside."
It has not been an easy road given two major challenges: spending cuts to the Pharmaceutical Benefits Scheme (PBS) and US giant Pfizer's decision to sell direct to pharmacies, bypassing wholesalers such as Sigma and
The federal government has been trying to cut its PBS costs since 2007. The reforms are aimed at cutting the government's costs by lowering the amount that it reimburses for generic drugs. It is estimated that of the $9 billion PBS, about a third of all scripts will be affected by the 23 per cent price cut to generic drugs from April 1. About 70 per cent of Sigma's sales are PBS products.
"The PBS reforms were designed to deliver at least 23 per cent savings to the government but the government looks like it will get significantly more savings than they anticipated," Hooper says.
Simga will cut back again on discounts given to pharmacies, says Hooper. He says there is no need for the government to implement further PBS reforms or it might start to restrict generic drug availability.
The move by Pfizer, which has the world's biggest-selling drug, the cholesterol-lowering Lipitor, to distribute its own products rather than contract companies such as Sigma to do it, cost Sigma 10 per cent to 15 per cent of its wholesale sales base. However, Hooper says he does not think other drug manufactures will follow Pfizer's direct model.
Deutsche Bank analyst David Low upgraded the stock to a "buy" in September, noting Hooper's strong track record for delivering results. "This has continued since he took over at Sigma, with the new management team under Mark turning around a struggling business in a difficult environment due to the highly disruptive exit of Pfizer from the wholesale channel," Low says. "Mark has subsequently outlined clear return-on-invested-capital targets which we are confident will be delivered over the next few years."
Sigma's return on invested capital has doubled in 18 months to around 13 per cent, in part through stripping out capital invested in the business.
In January 2010 Sigma had $668 million of working capital deployed and by July 2011 Hooper had whittled it down to $522 million by reducing creditor days from 90 to 72. While the balance sheet is in better shape, there's more work to be done.
Hooper is putting more resources in the retail business which houses the Amcal and Guardian pharmacy network of nearly 500 stores. He says the business has been neglected over the years. "Retail has become much more important to what we can offer the pharmacy. We are reinvesting in private label, which I think is a real opportunity," he says.
Hooper swims five kilometres a week and says exercise keeps him balanced – particularly when things get tough at work.
He also relaxes by watching his beloved Collingwood Magpies in the AFL. "It's one of the great things in life to go to a football game and scream your lungs out," he says.
The Australian Financial Review


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subset: commoncrawl


text:
The Baby Illusion
A new study confirms the baby in the family will always be the baby.
Not only that, but the youngest child will most often be perceived as shorter than he or she really is, even by mom.
The study's authors call it the "baby illusion," and they say mothers underestimated the height of their youngest by an average of 3 inches, but they accurately judged the height of any older children they had.
The study just published in the latest issue of Current Biology says it may be an adaptive mechanism, so that moms will nurture and protect the most vulnerable offspring.
The lead researcher says this explains why the baby of the family will always be seen as the baby.
--Rob Archer


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STANFORD, Calif. (AP) - Chasson Randle and Josh Owens each scored 14 points in helping Stanford beat Pacific 79-37 on Monday night.
Aaron Bright had six assists for the Cardinal (6-1), who recorded the largest margin of victory against Pacific in 36 overall games.
Travis Fulton scored 13 points to pace the Tigers (2-3), who have lost three of their last four.
Randle scored 11 of his points in the first half, helping Stanford take a 38-23 halftime lead.
Fresh off a visit to Madison Square Garden, where the Cardinal reached the championship game of the NIT Season Tip-Off Classic, Stanford looked comfortable from the start and eventually built a 20-point advantage early in the second half.


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Online marketer and web developer Lloyd Waggener has a passion for creating and understanding new great ways to grow your business online. With the always changing world online he works with businesses to find and implement the most beneficial ways to grow their business through the internet. Interviewed by Michelle Brubaker at: http://goo.gl/DU3TZz. #Podcasts
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Artspace developers want to build affordable work and living spaces for artists in Augusta, but it could take years and miles of bureaucratic red tape before that becomes a reality.
The nonprofit real estate development company returned to Augusta on Monday to reveal the results of a survey conducted this summer that gauged demand for a potential project. Of 602 artists surveyed, 186 would be interested in renting either a blended apartment/work studio space or a creative space alone.
Artspace project manager Joe Butler said that interest could make Augusta a candidate for a 50,000-square-foot, 40-unit project ideally set in the cultural district of downtown, bordered by the Savannah River, 10th, Walker and Fifth streets.
What's needed now is governmental support so a lengthy process of securing funding and feasibility planning can begin.
"If Augusta wants this, it's going to require some local champions," Butler said. "Folks that will continue to have a vision over the course of the next several years."
The Augusta Commission must now take up the issue of signing on to a pre-development contract with Artspace, which Mayor Deke Copenhaver said could be discussed within the next several months. If a contract is signed, the group would begin "a deeper level of information gathering," that would include forming a steering committee, identifying potential buildings to renovate, and applying for funding, Butler said.
Artspace utilizes federal low-income housing tax credits to pay for roughly 60 percent of project costs. The rest is paid for in philanthropic donations and city and state funding.
Vice president for special projects Roy Close said the low-income tax credits are useful but are difficult to secure and not guaranteed. He said he hopes government officials approve the partnership with Artspace sooner rather than later so the group can begin applying for the tax credits before Georgia's 2014 deadline.
It could then take a three- to four-year process to complete a project, he said.
"This is not just for the artists," Cross said. "This is for the community. It's been measured, and these projects do in fact make for stronger neighborhoods."
Since its launch in 1979, Artspace has completed 35 projects across the country, with 12 more under construction or in the pre-development phase.
Of the 186 interested artists in Augusta, 41 percent live at or below 60 percent of the area median income, boosting the project's chances of securing the tax credits.
Forty-three percent use a space in their home to work and 40 percent don't have a dedicated space at all. The responders were largely younger than 30 years old and specialized mostly in painting, drawing, music and photography.
Augusta jazz musician Karen Gordon said blended artistic real estate not only helps the artists but could also bring a revitalization to the culture of downtown.
"To have a place where artists, musicians, sculptors and painters could work and live together, it's just exciting," she said. "Collaboration is important in all industries, not just education not just technology ... it reminds me of the Harlem Renaissance, some artists and musicians supporting each other's projects."
Jesse Lee Vaughn, painter and owner of Americana Artworks and the Haunted Pillar Tattoo parlors, said the building could help solve a problem many artists find in Augusta, which is a lack of affordable real estate to create art or make music.
Copenhaver said the commission has been supportive of the Artspace concept since developers first visited the city in 2012. However, it could take some time, especially with holidays approaching, to have a public discussion and vote.
In the meantime, Greater Augusta Arts Council Executive Director Brenda Durant said the community must keep the Artspace project on the radar. She urged supporters to prepare questions to pitch to November 2014 election candidates as they campaign around the city, and let them know this is a priority.
"If the question is continually asked ... that's going to resonate," she said.


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I'm going to say something critical about this shoot featuring Zach Dare, Matthew and Nikita Ruben, but I think that a lot of you might agree a little… they kinda look like they're members of a cult. lol
Okay, maybe that's just a symptom of the style and the matching outfits in several of these photos, but there is definitely something about it that makes the whole thing just a little strange, and a little too clean and tidy too.
I have to confess that I usually don't like guys who seem a little too clean-cut and "boy next door" type, but in this case I think I would be able to make an exception. In fact I would be willing to make three exceptions lol
Michael Del Buono is the photographer responsible for these photos, with all three looking rather delicious despite their potential cult member appearance 😉
It's no secret that I am a fan of certain styles of photography, and the setting and appearance of this collection definitely makes me think back to the photography of the 1950's and 60's. That's helped by the clothing too of course.
All in all, it's a nice shoot with three very attractive young men. Enjoy! 😉


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Post-polio syndrome (PPS) is a condition that affects
survivors. About 20% to 40% of people who recover from polio will later develop PPS. The onset may occur 10 to 40 years after the initial polio attack.
The exact cause is unknown. It is not due to renewed progression of the original polio infection. However, long-term damage to nerve and muscle cells caused by the polio may contribute to the development of PPS.
These factors increase your chance of developing PPS. Tell your doctor if you have any of these risk factors:
Symptoms may include:
Copyright © Nucleus Medical Media, Inc.
If the symptoms during the first attack of polio were severe, the symptoms of PPS may also be severe.
The doctor will ask about your symptoms and medical history. She will also do a neuromuscular exam. PPS may be hard to diagnose because symptoms come and go. The symptoms also overlap with other diseases.
Testing often involves electromyography. This measures electrical activity in affected muscles. Other, less common tests may include:
Treatment focuses on managing symptoms. The goals are to:
Treatment may include:
There are no guidelines for preventing PPS. But, polio survivors who keep physically fit are probably at reduced risk.
March of Dimeshttp://www.modimes.org/
Post-polio Healthhttp://www.post-polio.org/
Canadian Orthopaedic Associationhttp://www.coa-aco.org/
Health Canadahttp://www.hc-sc.gc.ca/index_e.html/
Dalakas M. IVIg in other autoimmune neurological disorders: current status and future prospects.
Journal of Neurology.
2008;255(Suppl 3):12-16.
Howard R. Poliomyelitis and the postpolio syndrome.
. 2005;330:1314-1318.
The Post-polio program. National Rehabilitation Hospital website.
Available at:
Post-polio syndrome. Mayo Clinic website. Available at:
. Updated March 2, 2008. Accessed February 9, 2009.
Rowland LP, ed.
Merritt's Neurology
. 11th ed. Philadelphia, PA: Lippincott Williams & Wilkins; 2005.


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Site created 12/15/97.
page created: 6/13/00
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Here are some cool images for you... an exclusive first look at the menu screens for a whole slew of upcoming Paramount DVD titles, all designed by 1K Studios! Just scroll down each page to see the images, and you'll find a link to the next page's worth at the bottom. Special thanks to our friends at Paramount Home Video for the screenshots. They'll take a moment to download, so be patient. Enjoy!
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24 August, 2011@5:25 pm
10 comments
At his most vulnerable moment, Royce Da 5'9 released the greatest album of his career, Death Is Certain. After a falling out with former friend and collaborator, Eminem, Royce was a broken man, watching his chance to blow up slip right through his fingers. These events compelled him to write some of his most honest, self-examining music ever; a change from the usual fantasies that many other rappers regularly indulge in. But while Death Is Certain was an album with a gray cloud looming over it, it also marked a new beginning for Royce. It showed that he didn't need Eminem to make great music, and as he suggests later on his new LP, those events needed to happen to get to this point. With old beefs squashed and the signing of his Slaughterhouse crew to Shady Records, Royce predicts that Success Is Certain.
Yet with Success Is Certain acting as a sequel to his most critically lauded LP, it would seem that this LP would delve more into the introspective side of things, like it's predecessor. We all know that Royce can body virtually any track he touches, as he does on the abrasive album opener "Legendary", it's follow-up track, "Writer's Block" and later on "Where My Money". But given the majority of the album's overly abrasive production, it's almost overkill, as it's coming off hot off the heals of his Bad Meets Evil collaborative record with Em, where the duo rapped circles around each other for 10+ songs – and over better beats.
There are introspective moments on this LP, such as "Merry Go Round", where Royce amazingly recounts his fallout with the Shady/Aftermath camp, over more headcracking production: "Then I went from writin' for Dre / To wonderin' if my head was on straight / on the sidelines, feelin' I forgot about listenin' to "Forgot About Dre" / From there I went to about a bottle a day / Tellin' who we know "Get outta my face!" / okay I know what Kino said about Dre / I look at Kino to this day / like that was a stupid mistake / But if it wasn't for him doin that, what would I be doin today? / If it wasn't for Ca$his sayin' that he gonna beat my ass / Then me and Em prob'ly wouldn't be laughin bout us gettin past it / If it wasn't for me bein outcasted I woulda never been on the underground rappin wit…. SLAUGHTERHOUSE!" Get 'em, Royce.
On a more somber note, "Security" is the album's most somber note, and overall, it's best track. This song is the closest thing to something that one might hear on the original Death Is Certain, as he delivers his perspective on the death D12 member, Proof. This is followed by the requisite DJ Premier track, "Second Place"; and while it's not quite "Boom", it still delivers.
All in all, Success Is Certain is a pretty solid LP, despite some over-the-top production, and at times, shallow subject matter. As a sequel to Death Is Certain, he could have eased back and given us some more insight on the man behind the microphone. But we doubt this will halt his chances for success….
3.5 seems a bit generous. The production on this is for the most part, not good. Then you have the sing-songy hooks on some tracks. The subject matter is pretty boring stuff that has been covered many times before. His flow is beginning to sound more like eminem than his own. The days of tracks like 'Im the king', 'Take his life' , 'Boom', 'Soldiers Story' are definitely behind him it seems.
Yeah… I'm gonna have to go with a 3 my self. If he re-mastered/mixed the first half of the Street Hop project and kept about 4 songs on this project, he would have had a classic!
After Bad Meets Evil I thought I'd hear something devastating lyrically, but this album was a bit meh. Not even a 3 in my opinion. Definitely going to pop Street Hop back in.
Solid 4/5 for me…He mixed his street hop flow with the darkness of death is certain to make another dope LP.
I give it a 4. Royce is a beast with the lyrics. Every album doesn't have to break new ground. This is a very solid effort. The primo joint was fire of course. I think he is a victim of high expectations, especially from the underground crowd. I thought street hop was a 4.5.
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Babylon Sisters
Babylon Sisters
By Pearl Cleage
One World, Paperback, 9780345456106, 309pp.
Publication Date: February 28, 2006
Now B.J., a renowned newspaper correspondent, is back in town and needs Catherine's help cracking a story about a female slavery ring operating right on the streets of Atlanta. Catherine is eager to help B.J., despite her heart's uncertainty over meeting him again after so long, and confessing the truth to him and their daughter.
Meanwhile, Catherine's hands are more than full since she's taken on a new client. Atlanta's legendary Miss Mandeville a housekeeper turned tycoon is eager to have Catherine staff her housekeeping business. But why are the steely Miss Mandeville and her all-too-slick sidekick Sam so interested in Catherine's connection to B.J.? What transpires is an explosive story that takes her world not to mention the entire city of Atlanta by storm.
From the New York Times bestselling author of What Looks Like Crazy on an Ordinary Day . . . comes another fast-paced and emotionally resonant novel, by turns warm and funny, serious and raw. Pearl Cleage's ability to create a gripping story centered on strong, spirited black women and the important issues they face remains unrivaled.
From the Hardcover edition.
Praise for Pearl Cleage and Babylon Sisters
"Pearl Cleage's wonderful new novel, Babylon Sisters, shows a writer at the top of her game, managing to weave together the eternal dance of mothers and daughters, a timeless love story, rich friendships, and international politics into a fast-paced Atlanta saga with an unforgettable villain and a thrilling climax that leave us cheering. Pearl has once again given us a book filled with folks who are so real, we think we know them, or wish we did."
–e. lynn harris, author of Since I Lost My Baby
"Babylon Sisters' funny, feminine, fabulous voice sings a story of history, family, love and redemption. Cleage's ability to make the personal political and the political personal triumphs once again! Nestled in this beautifully written ode to love–of child, friends, men, and self –is a call to political activism and empowerment."
–Jill Nelson, author of Sexual Healing
"You'll love this savvy love story in which Pearl Cleage returns to Atlanta and the West End community and nails it! Cleage knows her city. She knows her community. She knows her people. Pearl Cleage knows her stuff!"
–Tina McElroy Ansa, author of You Know Better and The Hand I Fan With
"Babylon Sisters is a delectable feast! Pearl Cleage's people are my people. Their world of problems is complex and radiant, covering a wide spectrum of contemporary political and cultural issues. Cleage writes with the intelligence of a master storyteller and her underlying humor keeps our spirits high. Like flower petals swept into the sky by a warm wind, Babylon Sisters carried me away from all worries, reminding me that great writing changes your life."
–Deborah Santana, author of Space Between the Stars
"Cleage writes with amazing grace and killer instinct."
–The New York Times


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BOWLING GREEN, Ohio: After a series of first quarters in games that saw the Akron Zips (1-4, 0-1) tally three points total for the season in that period, the Zips made a fervent effort to come out quickly. Next time they might want to finish.
The Zips took a 14-3 lead in that first quarter against the Bowling Green Falcons (4-1,2-0) only to give up 28 unanswered points and allow the Falcons and in particular their running back Travis Greene dominate the rest of the way en route to a 31-14 loss at Doyt Perry Stadium Saturday afternoon.
Travis, a player who came in the game averaging 102.2 yards per game, not only ran over the Zips with 142 yards on 24 carries, but he damaged them to the tune of 71 yards receiving on four receptions, a career high. He scored two touchdowns. BG racked up 396 total yards on offense
The defense had moments when they battered Falcons quarterback with six first-half sacks, but passing wasn't the problem then. The Falcons running game proved to be an altogether different story as starting running back Travis Greene racked up yardage in chunks to move the ball for his team.
Greene came into the game averaging 102.2 yards per contest. By the end of the first half he's already racked up 95 against the Zips defense.
The Zips felt his presence even more in the second half with momentum shifted decidedly in the Falcons favor. UA went three-and-out on their first possession and punted the ball where BG took over at their on 31. Eleven plays later they hit pay dirt after a William Houston two-yard TD plunge.
The Falcons can thank Greene's efforts on the drive. Held without a reception at halftime, he caught three balls for 41 yards on the drive as he just bided his time until BG quarterback Matt Johnson found him after check downs on that drive. He also added eight yards rushing.
However, he wasn't finished. Moments later, BG quarterback Matt Johnson, who avoided the Zips' rush in the second half by rolling out to seek out his receivers, found himself scrambling and hit Greene with a short shovel pass that he took 30 yards for a 24-14 lead at the 1:41 mark of the third quarter. For good measure he added an 11-yard TD run later.
UA unleashed a quick strike early on to take a rare first quarter lead after surviving an interception scare and being granted a first down on a questionable pass interference call. Moments later quarterback Kyle Pohl found sophomore wide receiver L.T. Smith streaking down the far side line wide open for a 51-yard TD reception.
With the defense playing stout early on, the Zips, led by Pohl and another assist from a BG penalty, this time on a defensive hold, marched 72 yards on 12 plays for a touchdown drive capped by a three-yard run by their quarterback to give the Zips a 14-3 lead.
But despite that effort it soon became a case of this time around that the Zips would have to finish as well as they started. The score tells the story.
Quick hits: Wide receiver Dee Frieson was out for the Zips and backup quarterback Nick Hirschman didn't even make the trip with the team to Bowling Green.


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The Preachers of LA finale episode ended with a bang. Deitrick gathered the family together during the wedding reception and announced that he and Dominique were expecting another baby!
Now I'm wondering if Preachers of LA will get another season. You know, I hope it does because I want to see more of Dominique's mom, Faye. She is hilarious!! When she said she had to go and "put her hair on" while they were getting ready for the wedding, I was too done!! LOL!!
Check out what Deitrick blogged about the new baby:
When I found out Dominique was pregnant, it was a surprise and a blessing at the same time. Both my children were surprises to me, but they're here, and I am grateful. I always wanted kids, and God saw me fit to bless me with a family — and he's blessing me fast! Dominique can certainly have babies really strong. Plus, Dominique and I are really attracted to each other, physically, spiritually and emotionally, so I have to be careful or I'll suddenly have 12 children with her!
We're having another baby girl! Destin really needs a baby sister, because she needs to stop bossing me around. We're naming her Denver Monroe Haddon, unless I get an epiphany and decide to change it. But we're definitely sticking with the D names: Deitrick, Dominique, Destin, Denver.
The wedding was perfect. When I saw Destin walk down the aisle, she let me know that the test, the trial, the persecution was all worth it. It was God telling me: "Deitrick through it all, I'm still rewarding you, even through your failures, I'm still blessing you." Yet, according to people, I was wrong. I'm not a man of God…Because of my daughter? At the end of the day, a child is a blessing of the Lord. Seeing that really lifted a load off my shoulders, and at the end of the day, I'm winning.
Then, when I saw Dominique come after her, it was overwhelming for me. I'm a man's man. I don't believe in crying, but I couldn't contain myself. I was thinking about all that Dominique had gone through. She didn't ask for this world.
Read the rest over at the Oxygen website!!


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I love the feature of Captive Portal! I do have a couple
1) I don't have a radiu server. Is there another way of benig able to
authenticate using username/password?
2) I would like to ad graphics to my Portal Page. Where do I store the
graphics? How to I reference them in the HTML?
marshall at dias dot ws


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Kartepe Climb rankings
Difficulty ranking world: 626 (all)
Ranking Turkey: 5 (all)
Ranking Strandzha: 1(all)
Difficulty score: 133.19 what?
Kartepe Climb ratings
(rate it)
The Kartepe Climb is situated in Kocaeli. This climb belongs to the Strandzha.
Starting from Maşukiye, Kocaeli,
the Kartepe Climb ascent is 16.36 km long. Over this distance, you climb 1267 heightmeters.
The average percentage thus is 7.7 %.
Look for other sides to climb the Kartepe Climb.
Click here to open big profile.
Click here to open detailed route.
Find climbs close to the Kartepe Climb: within 10 km - within 20 km - within 50 km
Find all climbs and cols in Kocaeli on a map.
Find all climbs in the Strandzha in Turkey on a map.
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Did you climb the Kartepe Climb? Please send your cycling story, description or comments. You can also send us video's or send us pictures on the Kartepe Climb.
© climbbybike™ All rights reserved 2005 -


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Date: Tuesday, September 12, 2000 @ 17:06:57 Author: tgl Update of /home/projects/pgsql/cvsroot/pgsql/src/backend/optimizer/prep from hub.org:/home/projects/pgsql/tmp/cvs-serv27911/src/backend/optimizer/prep Modified Files: prepkeyset.c prepunion.c ----------------------------- Log Message ----------------------------- First cut at full support for OUTER JOINs. There are still a few loose ends to clean up (see my message of same date to pghackers), but mostly it works. INITDB REQUIRED!
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Agency Response Letter GRAS Notice No. GRN 000349
Return to inventory listing: GRAS Notice Inventory
See also Generally Recognized as Safe (GRAS) and about the GRAS Notice Inventory
CFSAN/Office of Food Additive Safety
July 14, 2011
Robert S. McQuate, Ph.D
GRAS Associates, LLC
20482 Jacklight Lane
Bend, OR 97702-3074
Re: GRAS Notice No. GRN 000349
Dear Dr. McQuate:
The Food and Drug Administration (FDA) is responding to the notice, dated August 6, 2010, that you submitted on behalf of GLG Life Tech, Ltd. (GLG Life Tech) in accordance with the agency's proposed regulation, proposed 21 CFR 170.36 (62 FR 18938; April 17, 1997; Substances Generally Recognized as Safe (GRAS); the GRAS proposal). FDA received this notice on August 9, 2010, filed it on August 17, 2010, and designated it as GRN No. 000349.
The subject of the notice is purified steviol glycosides with rebaudioside A and stevioside as the principal components (hereinafter referred to as SG-RS). SG-RS is obtained from the leaves of Stevia rebaudiana (Bertoni) Bertoni. The notice informs FDA of the view of GLG Life Tech that SG-RS is GRAS, through scientific procedures, for use as a general purpose sweetener in foods, excluding meat and poultry products and infant formulas, at levels determined by good manufacturing practice, as well as use as a table top sweetener. GLG Life Tech notes that purified steviol glycosides have recently been the subject of several GRAS notices and that FDA responded to these GRAS notices informing the notifiers that, at the time of its response, the agency had no questions regarding their conclusions that the purified steviol glycosides that are the subjects of their respective notices are GRAS for their intended use as a sweetener in food.
The SG-RS that is the subject of GRN 000349 is a highly purified preparation of rebaudioside A and stevioside from the leaves of the stevia plant. As such, FDA notes that a GRAS notice for the use of a specific purified preparation from stevia, such as SG-RS, and FDA's response do not necessarily apply to the uses of other stevia products.
Our use of "SG-RS," "steviol glycosides," or "purified steviol glycosides with rebaudioside A and stevioside as the principal components" in this letter should not be considered an endorsement or recommendation of that term as an appropriate common or usual name for the purpose of declaring the substance in the ingredient statement of foods that contain that ingredient. Title 21 CFR 101.4 states that each ingredient must be declared by its common or usual name. In addition, 21 CFR 102.5 outlines general principles to use when establishing common or usual names for nonstandardized foods. Issues associated with labeling and the appropriate common or usual name of a food are the responsibility of the Office of Nutrition, Labeling, and Dietary Supplements in the Center for Food Safety and Applied Nutrition.
As part of its notice, GLG Life Tech includes the report of a panel of individuals (GLG Life Tech's GRAS panel) who evaluated the data and information that are the basis for GLG Life Tech's GRAS determination. GLG Life Tech considers the members of its GRAS panel to be qualified by scientific training and experience to evaluate the safety of substances added to food. GLG Life Tech's GRAS panel evaluated the identity, method of manufacture, product specifications, and the potential exposure resulting from the intended uses of SG-RS as well as published and unpublished studies related to the safety evaluation of SG-RS. Based on this review, GLG Life Tech's GRAS panel concluded that SG-RS, produced consistent with good manufacturing practice and meeting appropriate purity and food grade specifications, is GRAS, by scientific procedures, under the conditions of its intended use.
GLG Life Tech provides information about the identity and composition of SG-RS. GLG Life Tech describes SG-RS as a white to light-yellow hygroscopic powder composed of ≥97% (on a dry weight basis) steviol glycosides, a group of structurally-related sweet compounds that are natural constituents of the stevia leaf. Rebaudioside A (CAS Reg. No. 58543-16-1) and stevioside (CAS Reg. No. 57817-89-7) are the principal steviol glycoside components of SG-RS and account for ≥95% of its total steviol glycosides content. Other steviol glycosides, including rebaudioside C (CAS Reg. No. 63550-99-2), dulcoside A (CAS Reg. No. 64432-06-0), steviolbioside (CAS Reg. No. 41093-60-1), and rebaudioside B (CAS Reg. No. 58543-17-2), may also be present. GLG Life Tech provides information about the manufacturing process and specifications for SG-RS. SG-RS is obtained from the leaves of S. rebaudiana (Bertoni) Bertoni through extraction and multiple purification steps. The leaves from a high stevioside-content variety are extracted with water. The extract is precipitated with ferric chloride and calcium hydroxide and filtered, followed by adsorption onto a resin. The resin is washed with ethanol and the resulting solution is decolorized with activated carbon and concentrated by evaporation. It is again decolorized with activated carbon, filtered and spray-dried. The spray-dried preparation is combined with similarly processed additional extracts, dissolved in ethanol and/or methanol, crystallized and filtered. The resulting preparation is subjected to further crystallization steps, filtered and spray-dried to obtain a high-purity stevioside preparation. Using leaves from a high rebaudioside A-content variety and similar production steps, a high-purity rebaudioside A preparation is separately obtained. These preparations are then blended to yield the final SG-RS product. GLG Life Tech provides specifications for its SG-RS that include the content of total steviol glycosides (≥97% by weight (w/w)) and limits for lead (≤1 milligram per kilogram (mg/kg)), arsenic (≤1 mg/kg), residual methanol (<200 mg/kg), residual ethanol (<5000 mg/kg) and microbial contaminants (within specified limits). GLG Life Tech states that the SG-RS product meets or exceeds the specifications for steviol glycosides established by the Joint FAO/WHO Expert Committee on Food Additives (JECFA) at its 69th meeting in June 2008.
GLG Life Tech estimates the intake of SG-RS resulting from its intended use in foods. GLG Life Tech largely relies on the consumer intake estimates provided by JECFA. JECFA used the WHO Global Environmental Monitoring System-Food Contamination Monitoring and Assessment Programme database to prepare international estimates of exposure to steviol glycosides (as steviol). JECFA assumed that steviol glycosides would replace all dietary sugars, at the lowest reported relative sweetness ratio for steviol glycosides and sucrose which is 200:1. Based on this assumption, the estimated daily intakes (EDIs) of steviol glycosides (as steviol) ranged from 1.3 milligrams per kilogram body weight per day (mg/kg bw/d) to 3.5 mg/kg bw/d. JECFA concluded that the replacement estimates were highly conservative and that a more probable EDI of steviol glycosides (as steviol) would be 20 - 30% of these values or 1.0 to 1.5 mg/kg bw/d. GLG Life Tech states that the use of SG-RS in food is self-limiting due to organoleptic factors and consumer taste considerations.
GLG Life Tech discusses published and unpublished studies pertaining to the safety evaluation of SG-RS, including studies on rebaudioside A, stevioside, steviol, and crude stevia extracts. Among the published studies considered were acute toxicity studies in rats, mice, and hamsters, subchronic toxicity studies in rats, chronic toxicity/carcinogenicity studies in rats, and reproductive/developmental toxicity studies in rats, mice and hamsters. GLG Life Tech also considers published and unpublished clinical studies and published and unpublished absorption, distribution, metabolism and excretion studies in animals and humans. Additional studies that GLG Life Tech discusses include published in vitro and in vivo mutagenicity/genotoxicity studies. Based on their consideration of all these studies, GLG Life Tech concludes that SG-RS is safe for its intended use in foods.
To further support its view that SG-RS is safe for the intended use, GLG Life Tech describes recent decisions by JECFA, the Food Standards Australia New Zealand (FSANZ) and the European Food Safety Authority (EFSA) on the safety of steviol glycosides for use in food as sweeteners. GLG Life Tech notes that JECFA established an acceptable daily intake (ADI) for steviol glycosides of 0–4 mg/kg bw/d (expressed as steviol) and FSANZ and EFSA established an ADI for steviol glycosides of 4 mg/kg bw/d (expressed as steviol). GLG Life Tech notes that, in EFSA's view, conservative estimates of steviol glycosides exposures in European adults and children suggest that it is likely that the ADI would be exceeded at the maximum use levels proposed by the petitioners whose submission was reviewed by EFSA.(1)
Standards of Identity
In its notice, GLG Life Tech states its intention to use SG-RS in several food categories, including foods for which standards of identity exist, located in Title 21 of the Code of Federal Regulations. We note that an ingredient that is lawfully added to food products may be used in a standardized food only if it is permitted by the applicable standard of identity.
Section 301(ll) of the Federal Food, Drug, and Cosmetic Act (FFDCA)
The Food and Drug Administration Amendments Act of 2007, which was signed into law on September 27, 2007, amends the FFDCA to, among other things, add section 301(ll). Section 301(ll) of the FFDCA prohibits the introduction or delivery for introduction into interstate commerce of any food that contains a drug approved under section 505 of the FFDCA, a biological product licensed under section 351 of the Public Health Service Act, or a drug or a biological product for which substantial clinical investigations have been instituted and their existence made public, unless one of the exemptions in section 301(ll)(1)-(4) applies. In its review of GLG Life Tech's notice that SG-RS is GRAS for the intended use, FDA did not consider whether section 301(ll) or any of its exemptions apply to foods containing SG-RS. Accordingly, this response should not be construed to be a statement that foods that contain SG-RS, if introduced or delivered for introduction into interstate commerce, would not violate section 301(ll).
Based on the information provided by GLG Life Tech, as well as other information available to FDA, the agency has no questions at this time regarding GLG Life Tech's conclusion that SG-RS is GRAS under the intended conditions of use. The agency has not, however, made its own determination regarding the GRAS status of the subject use of SG-RS. As always, it is the continuing responsibility of GLG Life Tech to ensure that food ingredients the firm markets are safe, and are otherwise in compliance with all applicable legal and regulatory requirements.
In accordance with proposed 21 CFR 170.36(f), a copy of the text of this letter responding to GRN 000349, as well as a copy of the information in this notice that conforms to the information in the GRAS exemption claim (proposed 21 CFR 170.36(c)(1)), is available for public review and copying at www.fda.gov/grasnoticeinventory.
Mitchell A. Cheeseman, Ph.D.
Acting Director
Office of Food Additive Safety
Center for Food Safety and Applied Nutrition
- Food and Chemical Toxicology 46:S61-S69. European Food Safety Authority. 2011. Revised exposure assessment for steviol glycosides for the proposed uses as a food additive. EFSA Journal: 9(1):1972.
- Renwick, A.G. 2008. The use of a sweetener substitution method to predict dietary exposures for the intense sweetener rebaudioside A. Food and Chemical Toxicology 46:S61-S69.
(1)FDA notes that EFSA, following a request from the European Commission, carried out a revised exposure assessment for steviol glycosides in children and adults from its use as a food additive (Ref. 1). In the revised assessment, the exposure estimate calculation uses the same methodology that was used by EFSA in its prior opinion on steviol glycosides but with revised use levels and food consumption data for children and the adult population. The mean dietary exposure to steviol glycosides (as steviol equivalents) for European children (1 to 14 years of age) ranged from 0.4 to 6.4 mg/kg bw/day, and from 1.7 to 16.3 mg/kg bw/day at the 95th percentile. Due to observed overestimations of consumption levels of non-alcoholic flavored drinks (soft drinks) by children at the 95th percentile within certain datasets, EFSA concluded that a correction factor was necessary. The corrected exposure estimate at the 95th percentile ranges from 1.0 to 12.7 mg/kg bw/day for children. For adults (UK population) mean dietary exposure to steviol glycosides (as steviol equivalents) were calculated to be 1.9 to 2.3 mg/kg bw/day and from 5.6 to 6.8 mg/kg bw/day for high level consumers (97.5th percentile). EFSA concluded that the main contributors to the total anticipated exposure to SGs are non-alcoholic flavored drinks (soft drinks) for both populations.
FDA further notes that studies conducted in the U.S., Canada, Australia, New Zealand, and Europe estimated the intakes of aspartame and other high intensity sweeteners using post-market surveillance data. Intake modeling methods are commonly used to estimate the consumption of a particular food or food ingredient. However, a realistic, but conservative approach is to estimate the intake of a sweetener based on the data reported in published studies. Estimates of intake for different sweeteners can be calculated based on adjustments for relative sweetness intensity. In a published study by Renwick (Ref. 2), the estimated intake of rebaudioside A, one of the primary steviol glycosides, was determined assuming a relative sweetness of 200 times that of sucrose. The consumption data were primarily from studies that used specifically designed food diaries combined with actual use levels or approved levels in different foods and beverages. These data were aggregated to provide an estimate of potential consumption of rebaudioside A.


text:
A newly discovered shipwreck in the Gulf of Mexico may have originally gone down 200 years ago. The ship is full of glass bottles, ceramic plates and boxes of muskets.
The shipwreck was discovered 200 miles (321 kilometers) off the Gulf Coast in more than 4,000 feet (1,219 meters) of water by a Gulf of Mexico mission led by the National Oceanic and Atmospheric Administration (NOAA). The wooden hull of the ship has nearly disintegrated, but a greenish copper shell that once protected the ship's wood remains behind.
"Artifacts in and around the wreck and the hull's copper sheathing may date the vessel to the early to mid-19th century," Jack Irion, a maritime archaeologist with the Bureau of Ocean Energy Management (BOEM), said in a statement.
The first hint of the shipwreck came in 2011, when a sonar survey by Shell Oil Company turned up an unknown blip on the seafloor. BOEM requested that NOAA explore such unknown blips during a recent expedition by the ship Okeanos Explorer. The ship returned April 29 from its 56-day mission exploring unknown areas of the Gulf.
3336 Calhoun Falls Highway
Elberton, GA 30635
Phone: 706-283-7800
Mon-Fri- 8am-5pm
Saturday - 9am-12pm
Sunday - CLOSED


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|Web Site Information :.
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Home Page - New Moon Coaching, Mid Life Coaching for Women Making New BeginningsDescription: Life coach and NLP practitioner Chris Moon-Willems from Worthing, Sussex, works with women over 50 dealing with events such as new beginnings, losing a spouse, mid-life career changes and retirement transition. Personal and group sessions.
Keywords: moving on after divorce, losing a spouse, women over fifty, retirement transition, new beginnings, mid life career changes, chris moon-willems, life coach, life coaching, personal coach, personal coaching, worthing, sussex, life skills coaching, build self confidence, NLP
Tags: newmooncoaching, coaching, new, life, moon, women, contact, home, mid, site, map, beginnings, making, page, coach, help, personal, time, career, retirement, copyright, prime, design, chris, friends, com, copperman, web, client, confidentiality, spouse, changes, willems, transition, losing, nlp, confidence, divorce, text, worthing,
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text:
Winnipeg's curling heritage is carved in Granite
- Updated: February 7, 2013
The spirit of the curling community is coming alive in Winnipeg as momentum builds for the 2013 Tim Hortons Roar of the Rings in the city where the traditions of the roaring game are so deeply ingrained in local culture.
The Canadian Curling Trials, slated for the MTS Centre Dec. 1-8, will feature our country's top 16 teams, competing in the emotionally-charged showdown with the right to represent Canada at the 2014 Olympic Games in Sochi, Russia, on the line.
"Winnipeg is a natural setting for this historic event," said Host Chair Mitch Tarapasky. "We've hosted Briers, Scotties and world championships… we're home to more national men's and women's champions than any other city in the country. Now, it's our time to crown Canada's Olympians for 2014."
The local history of the sport dates back to the 1870s when it was played in a rudimentary fashion in various locations around the city. The most significant development in the evolution of the game in the Manitoba capital came in 1880, with the formation of the Granite Curling Club.
Two years later, club founders established the city's first indoor curling rink at the corner of Hargrave Street and Ellice Avenue – coincidentally, just a block away from the site of the MTS Centre.
In 1911, with the sport growing in popularity, the club invested in property on the banks of the Assiniboine River and constructed a facility that was considered state-of-the-art for the era. The three-storey Tudor-style design included nine sheets of ice and elaborate facilities that made it a 'home away from home' for members.
The 'Mother Club', as it's affectionately known in curling circles, has also produced some of the legendary names in the game including Brier champions Howard Wood, Sr., Terry Braunstein, Don Duguid and Vic Peters.
When you come to Winnipeg this December for the Tim Hortons Roar of the Rings, set aside some time on your schedule for a visit to the Granite Curling Club – where the roaring game really started to roar more than a century ago!
"You Gotta Be There" when Canada's representatives for the 2014 Olympic Games proudly step up to the podium in the MTS Centre. Get your seats now – before the house sells out – just by clicking here.


text:
Frank Lee Humes
Forest Primeval
A pair of treasure hunters and a troubled psychic woman investigate a strange earthquake at Skull Mountain. Soon, they discover that the quake has unleashed a horde of demons into the surrounding forest. As the fiends torment one innocent victim after another, the trio must find a way to confront evil incarnate. Will they prevail and send the demons back to their lair, or will they suffer the worst fate of all in the forest primeval?


text:
Aquila received communication from Vale on Monday proposing an "interim solution" to the impasse over a joint marketing agreement for Isaac Plains, which has prevented coal being moved from the mine since early May.
As a result of the dispute, stockpiles have been mounting up and were expected to soon reach capacity. Had this occurred, mining activity would have had to stop and workers would have been laid off.
But Aquila said in a statement on Wednesday that after serving Vale with court proceedings, the Brazilian company would allow it to make a contracted shipment to China Steel Corporation.
Despite this victory, Aquila is still pursuing damages in respect to losses suffered on three shipments it was forced to cancel because of the dispute.
"Whilst [Aquila's] application for an urgent injunction to compel this [allowing the shipment to proceed] was not therefore required, the proceedings remain active in relation to the other remedies sought by [Aquila], including the claim for damages," the company said.
Aquila said Vale's proposal was being discussed as part of the continuing negotiations in relation to a longer-term resolution of the issues regarding separate shipments.
It believed the Isaac Plains joint venture agreement gave clear rights for each party to separately take its share of coal from the mine and deliver it to customers, but Vale disagrees.
The Australian Financial Review


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Lord Bassam of Brighton: My Lords, the principal reason is that the purpose of a photo driving licence is to permit a person to drive a vehicle, having passed a test. No doubt it is a useful means of identification and is often used in that way.
The Viscount of Oxfuird asked Her Majesty's Government:
Lord McIntosh of Haringey: My Lords, the Government announced on 26th April that they would consult on two new proposals to increase saving and asset ownership: the child trust fund and the saving gateway. The exact timing and cost of these policy proposals will depend on the results of the consultation process.
The Viscount of Oxfuird: My Lords, can the Minister tell the House whether income that accrues under either proposal will be subject to taxation? If not, how can it be fair to tax the savings of non-taxpayers, including pensioners and children who may have been bought privatisation shares by their parents, through the non-refundable stealth tax on dividend income introduced by the Chancellor?
Lord McIntosh of Haringey: My Lords, I thought that it would not be long before the Benches opposite moved from a debate on something which involved the transfer of money from government to people to their obsession with the transfer of money from people to government. The question of the tax status of the child trust fund and the saving gateway is one of the matters for consultation. Clearly, if there were to be tax relief for income under either or both of these measures the question would arise whether it became a regressive or progressive proposal in taxation terms. That is one of the matters which is being seriously considered.
Lord Naseby: My Lords, is the Minister aware that the expression "baby bond" is the registered trade mark of the Tunbridge Wells Equitable Friendly Society, of which I have the honour to be chairman? That is declared in the register. Is the noble Lord also aware that the primary work on this matter was done by the think tank IPPR, of which we were proud to be a co-sponsor? Is the Minister further aware that the friendly society movement, which has some 6 million members, looks forward to working with the Government to introduce the child trust fund and hopes that that movement will have a major role to play?
Lord McIntosh of Haringey: My Lords, I am particularly grateful for the last part of the noble Lord's question. I learnt only 10 minutes ago that he and his society had the prescience to register the expression "baby bond". My immediate conclusion was that they would begin to charge the Government for the use of that name. I am delighted to learn--I hope--that that is not the intention. But the main conclusion that I draw from the noble Lord's question is that we have some very valuable allies.
Lord Goodhart: My Lords, does the Minister agree that it would be better to divert this money into the cutting of tuition fees?
Lord McIntosh of Haringey: My Lords, the assumption of the noble Lord is very flattering to the Government. It is our intention that 50 per cent of young people in this country should benefit from higher education, but even when we achieve that target tuition fees would apply to no more than half of that 50 per cent. The proposals announced in April of this year apply to the whole population.
Lord Campbell of Alloway: My Lords, all this business about transfer of moneys this way and that does not make much sense. Is this not just a plain electoral gimmick?
Lord McIntosh of Haringey: My Lords, if governments could not make proposals for improvements in the welfare and happiness of the people of this country, that might be a serious question. There are still plenty of opportunities for us to continue making improvements of the kind that we have suggested.
Lord Saatchi: My Lords, is it not true to say that this baby bond is a fitting epitaph for a government who have always liked the idea of treating voters as babies? Perhaps the Minister will follow me in some baby arithmetic. There are 717,000 births roughly a year in this country. At Ł500 per head, this baby bond will cost the Government the sum of Ł350 million per year. Does the Minister accept that the Government have increased tax on voters by Ł28 billion per year? Therefore, the sum that the Government are so generously giving back amounts to just 1¼ per cent of the extra amount they have already taken in taxes. Does not the Minister think that even babies could see that coming?
Lord McIntosh of Haringey: My Lords, I am grateful for the preview of what will undoubtedly appear either on posters or on party election broadcasts for the Conservative Party. I am sure that the Chancellor of the Exchequer will be glad to have forewarning of the cutting edge of Conservative Party philosophy. In particular, the remarks about babies will go down very well.
The Conservative Front Bench and its Back-Benchers are showing the same predilection as was shown by the noble Viscount, Lord Oxfuird: that the only way to respond to a proposal to transfer money from government to the people is to change the subject. I notice that neither the Front Bench nor the Back Benches have recorded the fact that Mr Portillo said that he would not proceed with this project.
Earl Ferrers: My Lords, can the noble Lord explain why the Government feel that people cannot have babies without the Government paying them to do so?
Lord McIntosh of Haringey: My Lords, the Government do not feel that. They are not King Canutes. The urges which cause people to have babies will continue under any government.
Lord Blackwell: My Lords, can the Minister explain why the Government's support for the baby bond has not been matched by their support for the Opposition's proposal to fund pensions for young people? If the Government are to transfer money to individuals to try to encourage savings and self-sufficiency, would it not be more sensible to crystallise an existing liability on the state (for paying pensions) and to fund those rather than to create an additional liability on the state 18 years earlier?
Lord McIntosh of Haringey: My Lords, I find that a remarkable question. The Government have successfully introduced stakeholder pensions and are
The Viscount of Oxfuird: My Lords, will the Government agree that it would be more sensible if, instead of taking money away from non-taxpayers and then giving some of it back, they abolished tax on small savings altogether, as recommended by the party on this side of the House?
Lord McIntosh of Haringey: My Lords, that is about the third or fourth attempt to divert attention from the original Question to something quite different. We are aware that if the only benefit of what one noble Lord called "baby bonds" was tax relief, that would be regressive in personal taxation terms. That is why other things would have to be done, particularly in terms of the relationship with tax credits and with other forms of benefits, to ensure that the finalised proposals are not regressive but benefit the less well-off. The analysis of these matters is clear in the paper issued in April. I commend it to the noble Viscount.
Earl Russell asked Her Majesty's Government:
Lord Bassam of Brighton: My Lords, the Prime Minister's article made it clear that the United Kingdom is taking a lead in arguing for reform, not of the terms of values or principles of the 1951 convention, but of how it operates.
Earl Russell: My Lords, may I draw the Minister's attention to a reply given by his noble friend Lady Scotland of Asthal? She said that:
Lord Bassam of Brighton: My Lords, I cannot agree with that. The noble Lord is drawing attention to an important article which relates in part to the
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Regisatration Open For NGFA 2014 Country Elevator and Trade Show ... Dec. 7-9 ... Indianapolis, IN
Date Posted: July 31, 2014
Here is a link to information and registration for the 2014 NGFA Trade Show: http://www.ngfa.org/events/upcoming-events/country-elevator-conference/2014-cec-trade-show-prospectus-and-application/
Note the link to our floor plan -- and a separate link to the application form, which can be printed and filled out, then emailed to me.
Space will be assigned on a first-come, first-served basis in the order applications are received (last year's exhibitors received the show information on Monday, so some spots already are reserved).
Email your form to me at email@example.com.
Don't wait, because the spots perceived as most desirable will go very quickly!
I expect the show to sell out quickly again this year -- don't be shut out!
Per the floor plan, the Exhibit Hall will be located in Sections 1-5 of the Grand Ballroom on the 3rd floor of the J.W. Marriott in Indianapolis.
Conference sessions will be conducted immediately adjacent to the show in Sections 6-10 of the Grand Ballroom -- the section that backs up against the 100s row of exhibit spaces.
The "daisies" in the middle of the floor plan simply represent the food/beverage area -- the actual layout of tables will be different.
Receptions on Sun. and Mon. evenings, breakfast on Mon., and the big buffet lunch on Mon. will be conducted in the show.
Food service and a relatively small amount of lunch seating will be in the Grand Ballroom, with most seating for the buffet lunch in pre-function space outside the Grand Ballroom.
Access to the Grand Ballroom is gained from the lobby via escalators shown on the far right of the floor plan and from guest rooms via elevators to the right of the Ballroom as shown on the plan.
Doors to the show will be opened along the right side of the hall and along the bottom of the hall, as shown on the diagram.
The full floor plan of the 3rd floor -- which includes Sections 6-10 where conference programming will occur -- can be seen on the hotel's web site here: http://www.marriott.com/hotels/event-planning/floor-plans/indjw-jw-marriott-indianapolis/
I hope to see everyone in Indianapolis on Dec. 7-8!
For more information, call 202-289-0873.
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