text:
These authors contributed equally to this work.
This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
Hepatocellular carcinoma (HCC) is a serious healthcare problem worldwide because of its increasing morbidity and high mortality rates. However, our understanding of the mechanism of liver tumorigenesis remains incomplete. We report the expression of myosin light chain kinase (MLCK) in the livers of rats with diethylnitrosamine (DENA)-induced HCC and investigated the correlation between MLCK and liver tumorigenesis by observing the expression of MLCK in a rat model of HCC. HCC was induced in rats by an intraperitoneal injection of DENA, and resveratrol-treated rats were orally administered resveratrol with 50 mg/kg body weight/day. The livers of rats were excised after 20 weeks and immersed in 10% formaldehyde prior to immunohistochemical and Western blot analyses for determining the level of MLCK expression. These analyses indicated that the MLCK expression was higher in the livers of HCC rats than in normal and resveratrol-treated rats. High level of MLCK expression was responsible for proliferation and anti-apoptotic effects. However, resveratrol down-regulated the expression of MLCK, which induced cell apoptosis and inhibited liver tumorigenesis in rats with DENA-induced HCC. Our results suggest that the over expression of MLCK may be related to the development of liver tumorigenesis.
Hepatocellular carcinoma (HCC), the most common type of liver cancer, is the fifth most common malignant tumor type worldwide and the second leading cause of cancer-related death [
Resveratrol, a phytoalexin that is readily available from several dietary sources, is reported to possess antitumorigenic properties in several cancers [
Apoptosis, also called programmed cell death, is a physiological cell suicide program in eukaryotic cells that has been suggested to play an important role in the maintenance of homeostasis by facilitating natural tissue turnover [
Rats were subjected to the experimental conditions described in the Experimental Section. The experiment was terminated 17 weeks after the final carcinogen dose. The final body weights of the rats in the carcinogen (DENA) control group (Group C) and the DENA+ carboxymethylcellulose-treated group (Group D) groups were slightly lower than those of rats in the normal control group (Group A) and carboxymethylcellulose-treated group (Group B) (data not statistically significant). Treatment with resveratrol (50 mg/kg/day) increased the final body weights of the animals in Group E compared to those in Groups C and D (data not statistically significant). There were no statistically significant differences in the liver weights between the groups. The relative liver/body weights of the rats in Groups C and D were found to be significantly higher (
There were no visible hepatocyte nodules in the livers of rats in the normal control (Group A,
The immunohistochemical examination of the liver tissues for MLCK confirmed that the expression of MLCK and the value of the MLCK integral absorbance in the livers in the DENA control (Group C, 230 ± 48) and DENA + carboxymethylcellulose-treated (Group D, 236 ± 43) rats were higher than in the normal control (Group A, 81 ± 12) and carboxymethylcellulose-treated (Group B, 84 ± 8) animals (
The Western blot examination of the MLCK expression levels in liver tissues confirmed that the expression of MLCK and the ratio of MLCK/β-actin (the internal control) in the livers of the DENA control (Group C, 210 ± 41) and DENA + carboxymethylcellulose-treated (Group D, 207 ± 43) rats were higher than the expression levels in the normal control (Group A, MLCK/β-actin ratio was set to 100) and carboxymethylcellulose (Group B, 98 ± 3) groups (
The apoptosis in the tumor samples from the rats was evaluated
The mean percentage of the number of apoptotic cells relative to the number of total cells (the apoptotic index, AI) in the livers of the DENA + resveratrol-treated (Group E) rats (76.4 ± 16.5) was much larger than in the normal control (Group A) rats (26.7 ± 7.6) and carboxymethylcellulose-treated (Group B) rats (25.6 ± 7.8) (
Over the past few decades, our increased understanding of the carcinogenic process at the cellular and molecular levels has led to the development of a promising new approach to cancer prevention, which is termed "chemoprevention" [
Regulating apoptosis has been reported to be a new strategy for the treatment and prevention of cancer [
Male Sprague-Dawley rats, which weighed 65 to 85 g at the beginning of the study, were obtained from Changlinhe Pharmaceutic Co., Ltd., Anhui, China. The animals were housed in polycarbonate cages and fed a commercial pellet diet with water
The rats were randomized into five groups. The animals were acclimatized to the laboratory conditions for approximately seven days before beginning the experiments. The rats in Group A were the normal control animals, while the animals in Group B received 100 mL/kg body weight/day carboxymethylcellulose (10 g/L) orally. Hepatocarcinogenesis was initiated in all other animals by intraperitoneal injection of DENA (100 mg/kg body weight/week) once a week for a period of 3 weeks. The rats were then randomly divided into three groups: A model group (DENA group, Group C), a control group (DENA+carboxymethylcellulose group, Group D) and a resveratrol-treated group (DENA+resveratrol group, Group E). The rats in the resveratrol-treated group (Group E) were given 50 mg/kg body weight/d resveratrol suspended in 100 mL/kg body weight/day carboxymethylcellulose (10 g/L) oral administration of which was done by gavage (
The rats in each group (
The liver tissue were sectioned at an average thickness of 5 μm and stored at −20 °C until use. The sections were blocked with 5% BSA (Sigma) and 5% normal rabbit serum (Vector Laboratories, Burlingame, CA, USA) and incubated with the rabbit anti-rat monoclonal MLCK antibody (Epitomics, CA, USA) overnight. The sections were then incubated with HRP-conjugated goat anti-rabbit IgG (1:200 dilution) and treated with a metal-enhanced 3,3′-diaminobenzidine (DAB; Thermo Scientific, Rockford, IL, USA) for 3 min. After thoroughly washing the sections, they were mounted on glass slides with Vectashield (Vector Laboratories, Burlingame, CA, USA). Each section and its integral absorbance of MLCK expression were examined by microscope.
The liver tissues were washed three times with phosphate buffered saline (PBS) and then lysed in RIPA protein lysis buffer containing a protease inhibitor cocktail (1% Nonidet P-40, 1% sodium deoxycholate, 0.1% SDS, 150 mM NaCl, 10 mM sodium phosphate buffer pH 7.2, 2 mM EDTA, 10 mg/mL aprotinin, 10 mg/mL leupeptin, 2 mM PMSF, 2 mM sodium orthovanadate, 10 mM sodium pyrophosphate, and 20 mM sodium fluoride). The lysates were centrifuged at 15,000×
The TUNEL (terminal transferase dUTP nick end labeling) assay was performed to determine the effect of resveratrol on apoptosis using the POD (peroxidase)
The primary analysis was a comparison among control group, carboxymethylcellulose-treated group, DENA control group, DENA + carboxymethylcellulose-treated group, DENA + resveratrol-treated group. The data of the nodule incidence data was analyzed using Fisher's exact probability test. Other data were presented as mean ± S.D. With statistical analyses by
In conclusion, we revealed that the MLCK expression was higher in the livers of HCC rats than in normal and resveratrol-treated rats. High level of MLCK expression was associated with inducing liver tumorigenesis and anti-apoptotic effects. Resveratrol down-regulated MLCK expression and inhibited HCC tumorigenesis via inducing apoptosis in tumor cells using a rat model of DENA-induced HCC.
This work was supported by research grants from the National Natural Science Foundation of China (No. 81071306) and the Natural Science Foundation of Anhui Science and Technology University (No. ZRC2011318). The language of this manuscript was improved by AJE.
The authors declare no conflicts of interest.
Hematoxylin/Eosin (H & E) staining of the non-nodular liver sections (400×). Normal control (
Immunohistochemistry analysis of myosin light chain kinase (MLCK) was performed in non-nodular livers of rats (400×). Normal control (
A Western blot analysis of MLCK expression was performed in rat non-nodular livers, and the ratio of MLCK/β-actin was determined (mean ± S.D.). Liver homogenates were prepared as described in the Experimental Section. The Western blot analysis was performed using an anti-MLCK monoclonal antibody and a β-actin polyclonal antibody. Laser scanning densitometry was conducted to quantify the differences. Normal control (Group A). The densitometric units of the control group (MLCK/β-actin) were set to 100, and the internal β-actin control is shown for the carboxymethylcellulose-treated group (Group B), the DENA control group (Group C), the DENA + carboxymethyl-cellulosetreated group (Group D), and the DENA + resveratrol-treated group (Group E). **
Terminal transferase dUTP nick end labeling (TUNEL) analysis of the apoptotic cells was performed in rat non-nodular liver and positive control slices and the apoptotic index of the rat non-nodular liver cells was determined (mean ± S.D.). (
Body and liver weights of different groups of rats (mean ± S.D.).
|Body weight (g)
|Liver weight (g)
|Liver weight (g)/Body weight (g) × 100%
|309.4 ± 23.2
|10.12 ± 2.01
|3.26 ± 0.23
|307.9 ± 32.1
|10.03 ± 2.89
|3.25 ± 0.31
|278.3 ± 31.2
|13.08 ± 3.24
|4.69 ± 0.47
|280.1 ± 29.6
|14.02 ± 3.53
|4.71 ± 0.56
|299.3 ± 27.1
|11.82 ± 2.25
|3.91 ± 0.36
Effect of resveratrol supplementation (50 mg/kg body weight/day) on the nodule incidence % and the development of persistent nodules in the livers of rats with diethylnitrosamine (DENA)-induced hepatocellular carcinoma (HCC) (mean ± S.D.).
|Number of rats with nodules
|Nodule incidence %
|Total number of nodules
|Average number of nodules per nodule-bearing liver
|36.8 ± 4.3
|36.2 ± 6.9
|10.1 ± 2.6


text:
There's a Polar Bear
In our Frigidaire--
He likes it 'cause it's cold in there.
With his seat in the meat
And his face in the fish
And his big hairy paws
In the buttery dish,
He's nibbling the noodles,
He's munching the rice,
He's slurping the soda,
He's licking the ice.
And he lets out a roar
If you open the door.
And it gives me a scare
To know he's in there--
That Polary Bear
In our Fridgitydaire.
Poet: Shel Silverstein
Poem: Bear In There
Volume: A Light in the Attic
Year: Published/Written in 1981
Are you looking for more information on this poem? Perhaps you are trying to analyze it? The poem, Bear In There, has received 338 comments. Click here to read them, and perhaps post a comment of your own.
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(20 poems)
Shel Silverstein books

subset: commoncrawl


text:
Tinea corporis is a skin infection due to fungi. It is also called ringworm of the body.
Related skin fungus infections may be found:
Fungal infection - body; Infection - fungal - body; Tinea of the body; Tinea circinata; Ringworm - body
Fungi are germs that can live on the dead tissue of the hair, nails, and outer skin layers. Tinea corporis is caused by mold-like fungi called dermatophytes.
Tinea corporis is common in children but can occur in people of all ages.
Fungi do well in warm, moist areas. A tinea infection is more likely if you:
Tinea corporis can spread easily.You can catch it if you come into direct contact with an area of ringworm on someone's body. You can also get it by touching items that have the fungi on them, such as:
Ringworm can also be spread by pets. (Cats are common carriers.)
The rash begins as a small area of red, raised spots and pimples. The rash slowly becomes ring-shaped, with a red-colored, raised border and a clearer center. The border may look scaly.
The rash may occur on the arms, legs, face, or other exposed body areas.
Symptoms may include itching.
Your health care provider can often diagnose tinea corporis by looking at your skin.
You may also need the following tests:
Keep your skin clean and dry.
Use creams that treat fungus infections.
To use this medicine:
Rarely, you may need medicine you take by mouth if your infection is very bad.
A child with ringworm can return to school once treatment has started.
To prevent the infection from spreading:
Infected pets should also be treated.
Ringworm often goes away within 4 weeks when using antifungal creams. The infection may spread to the feet, scalp, groin, or nails.
Call your health care provider if ringworm does not get better with self-care.
Elewski BE, Hughey LC, Sobera JO, et al. Fungal Diseases. In: Bolognia JL, Jorizzo JL, Schaffer JV, et al, eds. Dermatology. 3rd ed. Philadelphia, Pa: Mosby Elsevier; 2012:chap 77.
Hay RJ. Dermatophytosis and other superficial mycoses. In: Mandell GL, Bennett JE, Dolin R, eds. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases. 7th ed. Philadelphia, Pa: Churchill Livingstone Elsevier;2009:chap 267.


text:
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1 Pound Fresh Asparagus, with hard ends trimmed
1/2 Cup Kings Pecans, broken into pieces
2 Heads Red Leaf Lettuce, rinsed and torn
1 Cup Diced Cucumbers
1/4 Pound Smoked Sliced Salmon, cut into 2" pieces
1/4 Cup + 1 Tablespoon Olive Oil
2 Tablespoons Lemon Juice
1 Teaspoon Dijon Mustard
1/2 Teaspoon Salt
1/4 Teaspoon Pepper
1. Season trimmed asparagus with 1 tbls of olive oil , salt and pepper. Grill on a preheated grill until grill marks appear, approx. 3-4 minutes. Cut into 2" bias pieces and keep warm.
2. Place the pecans in a skillet over medium heat. Cook 5 minutes, stirring frequently, until lightly toasted.
3. In a large bowl, toss together the grilled asparagus, pecans, red leaf lettuce, cucumbers, and salmon.
4. In a separate bowl, mix the olive oil, lemon juice, Dijon mustard, salt, and pepper. Toss with the salad or serve on the side.
©2017 Kings Food Markets
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text:
Dream Or Nightmare: A Kentucky Fried Chicken-Scented Candle
I recently went on a fall candle shopping spree, so every room of my house is now filled with blissful smells like balsam wood, pumpkin pie, cinnamon, firewood, and cranberry peppermint. But you know what scent is missing from my candle lineup? KENTUCKY FRIED CHICKEN. Luckily, a Kentucky candlemaker named Kathy Werking has created just such a product, and she didn't take her job lightly. Check out the product description:
"To craft the perfect xtra crispy aroma, Kathy picks up her cast iron skillet, adds a little seasoning, and gets to work. To make these candles, she fries chicken in all-natural soy wax and adds an infusion of family secrets."
Yep, these candles are the real deal. If the thought of the aroma of fried chicken wafting through your house fills you with glee instead of dry heaves, you'll need to act fast: the first batch of 25 KFC candles sold out in under a minute, and the next batch of 100 is going fast! [$22, Kentucky For Kentucky]


text:
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text:
DVT deep vein thrombosis forum
|number of replies (4) - Page 1 of 1
Closed toe to open toe fix
Started by Char
|Posted: September 21, 2008 at 17:23
Has anyone made his or her closed toe support hose into open toe. I have opaque thigh high Medivens since the end of August, walking 5 miles a day has worn holes in the toes. Just how difficult would it be to make them open toe. Has anyone tried this fix? My Medivens were $60.00 and I do not want to buy another pair.
Re: Closed toe to open toe fix
Reply #1 by Linda
|Posted: September 23, 2008 at 23:13
Hi Char,
I don't have an answer to your problem but may I suggest that you try looking on EBAY the next time you are in the market for a new pair of compression stockings. I have bought many items from EBAY throughout the years and I have saved alot of money and have been quite satisfied with my purchases.
Re: Closed toe to open toe fix
Reply #2 by Linda
|Posted: September 23, 2008 at 23:17
Hi Char,
I think I bought my stockings from AmesWalker. Here is the link.
They appear to be discounting about 50%. I would also check EBAY.
Good luck. I hope you find what you are looking for.
Re: Closed toe to open toe fix
Reply #3 by Michelle
|Posted: September 24, 2008 at 13:20
I don't think it would be a huge deal to cut off the toes and make them open-toed. I've always had open-toed support stockings. Why not just cut the toe area out, and serge or sew the area over to make sure it won't run or unravel? As long as that area is kept loose - so the toes move freely and the blood supply is getting through, it should be fine. You don't have compression in the toe area anyway...or those of use with open-toed stockings would be missing out. Make sure you're still putting the stockings on correctly - the problem with open-toe is you tend to pull them up to high - so make sure your heel is correctly in place, and you should be fine.
Have you checked with your insurance company? Mine pay for 2 pair a year, as long as I have a prescription from my doctor. As I only have 1 bad leg, I get the knee-high ones, and 2 pair = 4 stockings, so I have enough to get through the year easily. I think I paid about $90 Canadian - so yours weren't that bad (mine were 40-50mm Hg - the highest compression you can get - maybe that's why they're so expensive).
Re: Closed toe to open toe fix
Reply #4 by Char
|Posted: September 24, 2008 at 18:26
Hey Michelle, that is exactly what I did on the thigh high toe; it had a hole at the toe area. Therefore I cut off the toe area just above the toe hole. Used a close zigzag stitch and it worked out perfectly. The opaque material was strong enough for the stitching and it fit on my foot/leg comfortably. I have no support hose insurance coverage and after all my laser surgery is finished I will go back to knee highs. Mediven Thigh highs will go in the garbage. Ugh


text:
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Former U.S. Deputy National Security Advisor Elliot Abrams says Americans should either support whatever decision Israel makes, or say "we think the U.S. should do it ... we should not leave this to Israel" Says Russia is now part of the Axis of Evil.
Elliott Abrams, who served as Deputy National Security Adviser for Global Democracy Strategy under former U.S. President George W. Bush, and as Washington´s resident Middle East adviser, is very concerned. Not only is he worried about the latest developments in the region, but also about the current U.S. president, Barack Obama. Currently, Abrams is a senior fellow for Middle Eastern studies at the Council on Foreign Relations in Washington. This week, Abrams came to Israel to take part in the 2012 Presidential Conference in Jerusalem and in a conference at the Begin-Sadat Center for Strategic Studies headed by Professor Efraim Inbar and agreed to share his views on regional developments.
During the Bush administration, Abrams was sent to Egypt to promote democracy. "We urged [recently deposed Egyptian President Hosni] Mubarak to begin the reforms. Not in one day, but to start having free elections," Abrams says. "I think that this trouble is really the result of his failure over a period of 30 years to move at all in the direction of democracy. Thirty years is a long time, if you start very small steps of reform, over 30 years you get pretty far. He did nothing, so the whole system collapsed."
"In September 2010 [when Obama hosted Israeli Prime Minister Benjamin Netanyahu, Palestinian Authority President Mahmoud Abbas, Jordanian King Abdullah II and Mubarak at a peace summit], nobody said anything to Mubarak about democracy and reform. It was as though it had all been forgotten. I think that was a mistake."
"I think that if one or two weeks before the end, Mubarak had gone on TV and said ´I am 82 years old. I´m not running for president again. My time is coming to an end,´ and ´this is not Syria: my sons are not going to take over. We´ll have an election.´ I don´t think any of this would have happened. I think this was a reaction to the sense that he was not giving an inch, and Egypt was facing another 30 years of the same thing with [Mubarak´s son] Gamal. That, I think, people were not prepared to accept. I think we made a mistake during the Bush administration in not pushing the reform agenda harder, and I think that Obama made a mistake in essentially abandoning it."
The results starting to come out of Egypt as the second round of presidential elections draws to a close, is actually encouraging, Abrams argues. "First of all, as I understand the results, [Egyptian presidential candidate on behalf of the Muslim Brotherhood, Mohamed] Morsi, is winning by a couple of percents. What that will show the Muslim Brotherhood is that this is essentially a fifty-fifty vote. Half of the people of Egypt didn´t want them. I think that strengthens the army. It gives a boost to their morale."
"We know that the army wants to keep this treaty [with Israel]. The brotherhood has signaled that it will keep the peace treaty. I worry a lot about Sinai, I think the security situation in Sinai is very dangerous, but I don´t think they will abrogate the treaty."
"The treaty will remain. But, they have a terrible problem in Sinai. You have Bedouins, you have jihadis, you have criminals, you have Hamas, it´s going to be a mess, and Israel is going to have to be dealing with this for a long time."
In Syria, where a 15-month uprising against the regime of Syrian President Bashar al-Assad has already taken thousands of lives, Abrams urges immediate American intervention. He reverts to Cold War terms in describing the battle Russia is waging against the U.S. via Syria´s "axis of evil" Iran and Hezbollah.
"I agree with the view that this is essentially a proxy war, in the sense that you have Russia, Iran, Hezbollah and the Assad regime. This is a real axis of evil. We cannot allow them to win. One country is arming this regime, and not just over the past decade, but now, now, [Russia is] continuing to sell arms. So in my view, here the strategic and the humanitarian go together."
"We (the U.S.) should have more sanctions for example: No planes can go to or from Damascus International Airport and land in Europe. Cut them off. And I think we should be arming the Syrian rebels. I think we have to do it secretly, for only one reason: You have to get the arms to them through neighboring countries, and the neighboring countries are likely to either not cooperate, or only cooperate if it is done in secret."
"I don´t accept the objection that we don´t know the opposition well enough this is how you can get to know them. When you work with them, when you give them money and arms you´ll find out who is a thief, who is competent and who is not competent. We do need to find that out, but you can´t find it out by making speeches in Washington."
"I´m told that there is a presence of al-Qaida and other jihadis [in Syria]. It should not surprise us. In this situation you have Sunnis being slaughtered by people they consider to be Shiites, essentially. So of course these jihadis will be attracted to go to Syria. Many of them have already been to Syria, because they went through Syria to get to Iraq in the first place. They want to fight this fight [for Assad]. The more this becomes an Alawi-Sunni fight, the harder it will be in the end to have any kind of reconciliation, so we should try to get this over, soon."
Abrams was serving in the U.S. National Security Council when Israel reportedly bombed the nuclear reactor in Syria in 2007. "Any Israeli prime minister would have reached the same conclusion: That reactor has to go. The question was whether the U.S. should do it, or Israel should do it. I thought Israel should do it. This was 2007, a year after the [Second] Lebanon War which many people in the region thought came out very badly for Israel [undercutting Israel´s deterrence]. This was an opportunity for Israel to show it was still in the game, still strong."
Perhaps hinting at current Western diplomatic efforts to persuade Iran to abandon its nuclear aspirations, Abrams recalls that "I thought that the idea of a diplomatic outcome [in Syria] was absurd. The reactor was a secret, and the fact that we knew about it, and that Israel knew about it, was also a secret. Assad did not know [that we knew]. If we had gone to the IAEA in Vienna and announced that we know about this and that it had to end, what would he [Assad] have done? He would put a kindergarten next to it and eliminated the military option. I think it would have been very foolish."
What about an Israeli attack on Iran?
"I do not advocate an Israeli strike on Iran, because I think that is a decision only Israelis can make. It is much too easy for me to sit in Washington, 5,000 miles away and say, yeah, attack Iran. Iranian missiles are not going to fall on my house and my family is not going to be at risk. I don´t think Americans should be for it or against it." Abrams says Americans should either support whatever decision Israel makes, or say "we think the United States should do it ... we should not leave this to Israel."
"But I don´t want to be perceived as saying Israel needs to do this tomorrow. Only Israelis will pay the price, therefore the Israelis need to make the decision."
Obama has already said that all the options are on the table.
"I think it´s not enough. We all want the negotiations [between the West and Iran] to succeed, but there is only one chance: If Iran´s Supreme Leader, [Ayatollah Ali] Khamenei] is persuaded that the United States is willing to attack, that he will never get a nuclear weapon. The president needs to make that clear. The president has said things that are ambiguous: he said to Israel ´I have your back,´ he said ´I don´t bluff,´ he said ´all options are on the table.´ What´s missing? A statement that says very clearly ´I will not permit Iran to get a nuclear weapon, if I have to use military force to prevent it, I will.´ The ayatollah needs to understand that he will never get a nuclear weapon while Obama is the president of the United States. And Obama hasn´t done that."
Abrams gives his analysis of the U.S. political arena, saying that "clearly the White House would like the Iran issue to disappear until after the election. They´ve come to the conclusion that anything having to do with Iran hurts the president. [Obama] is saying ´I´m getting us out of Afghanistan, I got us out of Iraq, war is receding´ and if there is some kind of attack on Iran, it makes it harder to assert that I think that is wrong politically. I think that this would actually help the president. I think even an Israeli attack would help the president. I assume that like any president he would back Israel, as he said he would. If the president seems strong, and says to the Iranians ´you´re not going to get a nuclear weapon; you´re not going to close the Strait of Hormuz; you´re not going to attack Israel, and the Saudis and the Emirates, and American bases in the Gulf,´ he would look strong and I think that the American people would support him. But apparently that is not the view of the White House."
"I think that they would be having a better negotiation [with Iran] today if Obama had said things clearly to the Iranians. But it´s not too late. He has become tougher. It was only recently that he said ´my policy is not containment, my policy is prevention.´ That was a good step forward, now take the next step and say ´my policy is prevention, and I will prevent it.´ I hope he will do that."
Abrams further speculates that there will not be any progress in the Israeli-Palestinian peace process, at least not until after the upcoming U.S. presidential election this coming November. "I don´t think anything is going to happen soon. I don´t see any serious negotiations, at least this year, because you have the U.S. elections and everyone wants to see who the president will be and what the American policy will be. This is an issue for 2013 or for 2014."
"I don´t think that Abbas today wants a serious negotiation. He´s waiting for the elections, and he´s waiting to see what happens with Iran, like everybody. I don´t see how he can make very big compromises, because Hamas will say ´you´re a traitor´. Remember that [former Israeli Prime Minister Ehud] Olmert made a big proposal in 2008. Why didn´t Abbas accept it? One of the main reasons was that he knew that Hamas would say ´Arafat never gave anything away; you gave it away, you´re a traitor to the Palestinian people; you´ve abandoned the refugees.´ I don´t think he´s going to do that."
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Alex McQuiston from Spike TV sent along the following: Sorry for the delay, but the below link has been updated and is no longer a private link. Thank you!
Enclosed is a PSA Spike created to support Wrestling's return as an Olympic sport.
Synchronized Swimming is in the Olympics but then wrestling has the possibility of being dropped. What the F*** is wrong with the Olympic board..
Wrestling aint that big outside the USA


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Popped over 'The Pond' to jolly old England, Scotland
7/3/2013 by BY WILLIS WEBB
If I?da known Billy Shakespeare?s momma was a Webb, I?da worked harder in English Lit classes.
But, I got a book full of lessons on my second ?pop over the pond? (that?s British for ?flew over the Atlantic?) on many things Brit and some things Scot.
London and Edinburgh are great places to visit, but I wouldn?t want to live in London (as the adage goes), however, I might ?ave a go at Edinburgh.
Since Webb is an English name, I?ve always wanted to go to Great Britain, particularly London. It is extraordinarily enjoyable, but I found Edinburgh more interesting and laid back.
My only personal purchase in the United Kingdom was a 100 percent pure wool Scot plaid tie. It?s an Ingles Buchan (brand, which doesn?t mean anything to me but maybe it will to someone more with it), in Stewart muted blue (that name doesn?t ring a bell either). I just liked the look of it and if I ever wear a tie again, it will go with at least two sport coats in my limited retirement wardrobe. This Scot tie is a ?relaxed,? informal look much more suited to my blue jeans tastes and mind.
Of course, when you go to a European country, such as the British Isles, you expect to see architecture much older than in America. Structures in most places are several centuries old. You won?t find much in America older than 250 years but, over the pond, a thousand years is not extraordinary.
Most structures are built of stone, brick or masonry. Wood is at a premium and in a nation as limited in space as Great Britain, the best bet has always been stone. Forests, replanting and 20-30-year growth are out of the question.
Most streets are well-worn cobblestone or brick. Compared to our concrete, asphalt and gravel streets, the British roadways are rough, but not enough to make for an unpleasant ride.
In addition, apartment buildings can extend several stories beneath the ground, in addition to many more stories tall. Often, one?s residence might extend under a street and down a few levels. And, most Englishmen live in apartments (quite often they own them).
As for mass transit, we don?t even have the beginnings of the concept down compared to our Brit friends. Trains are a major travel vehicle, both above and beneath the surface, in large cities and between towns. We took a train from London to Edinburgh, a four-plus-hour jaunt and it was great. The accommodations and service were first class coach. Libations and meals are as good or better as you?ll get on any mass transportation travel.
City bus service within both London and Edinburgh was outstanding.
Double-decker tour buses with at least part of the upper deck al fresco are a great way to get around. A ticket enables you to get off wherever you like, then board another bus at appropriately marked tour stops and continue your rounds. We did this in Edinburgh, and London to a lesser extent. However, we found riding the train or tube (underground train) the easiest way to get around London efficiently.
We splurged on one live stage show to break up the sightseeing and touring. Jersey Boys is a musical that has been running for several years in both London and New York?s Broadway and is, obviously, quite popular.
It is an American story of Frankie Valli and The Four Seasons. As you may recall, the music is great harmony and much of it the rock and roll beat that swept both countries in the 1950s-60s, when that group was at its zenith in the two greatest English-speaking countries in the world.
Thankfully, I had an aisle seat with plenty of passage room because my right leg stuck out with my foot tapping enough to the music that my knee was going up and down noticeably so even someone with Mr. Magoo glasses could see.
There?s much more of interest about the trip and from time to time I?ll spin a column or two about the UK trip and how old retired, po folks can swing it.
Willis Webb is a retired community newspaper editor-publisher of more than 50 years experience. He can be reached by email at email@example.com.


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ollowing up on our earlier article on the Reynolds Prairie, called by the Lakota Pe' Sla, "peace at the bare spot," the family selling the land and the tribes have come to an agreement. As reported by the Indian Country Today Media Network, a coalition of Lakota tribes put together an offer of $9 million for the land, which the owners accepted. They put down a 10% deposit, and the tribes now have until November 30 to complete the transaction.
(NEWS FLASH) Pe'Sla Sale To Lakota Nation Has Been Agreed To | Addicting Info
Current Status: Published (4)
Seeded on Thu Oct 4, 2012 8:15 AM
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We are the premier showcase and resource for independent film in Maine. We aim to strengthen Maine culture through education, dialogue and the celebration of film and art.
The Maine Film Center seeks to bring together our community's unique film assets to further establish Waterville's reputation as a vibrant, year-round center of film exhibition and education.


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The queen mother, like most of the royal family, was relaxed about their relationship.
The queen mother was said to have died with an overdraft at Coutts of more than £2 million; it was settled by her daughter.
Indeed, the king, the queen mother, and their intimate friends seemed to be in an ecstasy of joy.
The queen and the queen mother were dressed in cloth of gold.
The queen mother was unsound in the faith, although, from motives of policy, she dissembled her true sentiments.
It is her majesty the queen mother, who has come to visit Angers.
Then the queen mother said: "Dwell thou here with me, and our servants shall go in quest of thy husband."
The king rode between the queen mother and the King of Navarre.
I fancy I can manage a sort of preferment with Dubissay, who has the ear of the queen mother at present.
Those who hate me, sire, are Monsieur d'Alenon and the queen mother.


text: Well, I am trying to get slack going as best I can, using rc scripts. I have alsa done, and I created some dm scripts to start the display manager from init 3 instead of changing the default to init 4, my hope in this is to bypass the behavior noted in the inittab with runlevel 4, though I have not tested that yet. Now reading previous emails, I am thinking maybe of making usb totally modular and using the rc.usb to load usbcore as well, but as for the questions I have at this point: Thorsten, for compatibility where did you put gnome? Did you do /opt/gnome? The reason I ask is the path in my rc script needs to be temporarily altered for 'which' to work and set the full path to kdm, or xdm, etc... For my own personal use this doesn't matter but I would like to contribute these scripts to slackintosh. Now, for the life of me I can't figure out my modem, but for the first time a few minutes ago I ran lsof in slack and found out that something called kded is using /dev/tty/0 which I guess is a symlink to /dev/ttyS0. Now I am in gentoo and lsof doesn't even show kded, so any help would be appreciated. --Mike


text: CHRISTOPHER S. RUGABERWASHINGTON (AP) â¿¿ Some reward. Here's the assignment President Barack Obama has won with his re-election: Improve an economy burdened by high unemployment, stagnant pay, a European financial crisis, slowing global growth and U.S. companies still too anxious to expand much. And, oh yes, an economy that risks sinking into another recession if Congress can't reach a budget deal to avert tax increases and deep spending cuts starting in January. Yet the outlook isn't all grim. Signs suggest that the next four years will coincide with a vastly healthier economy than the previous four, which overlapped the Great Recession. Obama has said he would help create jobs by preserving low income tax rates for all except high-income Americans, spending more on public works and giving targeted tax breaks to businesses. He used his victory speech in Chicago to stress that the economy is recovering and promised action in the coming months to reduce the government's budget deficit, overhaul the tax system and reform immigration laws. "We can build on the progress we've made and continue to fight for new jobs and new opportunity and new security for the middle class," Obama said. The jobs picture has already been improving gradually. Employers added a solid 171,000 jobs in October. Hiring was also stronger in August and September than first thought. Cheaper gas and rising home prices have given Americans the confidence to spend slightly more. Retailers, auto dealers and manufacturers have been benefiting. That said, most economists predict the improvement will remain steady but slow. The unemployment rate is 7.9 percent. Obama was re-elected Tuesday night with the highest unemployment rate for any incumbent president since Franklin Roosevelt. Few think the rate will return to a normal level of 6 percent within the next two years. The Federal Reserve expects unemployment to be 7.6 percent or higher throughout 2013.


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National Water-Quality Assessment (NAWQA) Project
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Mahler, Barbara J., Van Metre, Peter C., Crane, Judy L., Watts, Alison W., Scoggins, Mateo, and Williams, E. Spencer, 2012, Coal-tar-based pavement sealcoat and PAHs: Implications for the environment, human health, and stormwater management: Environmental Science & Technology, vol. 46, no. 6, p. 3039-3045. doi: 10.1021/es203699x Available Online
Mahler, B.J., and Van Metre, P.C., 2011, Coal-tar-based pavement sealcoat, polycyclic aromatic hydrocarbons (PAHs), and environmental health: U.S. Geological Survey Fact Sheet 2011-3010, 6 p. Available Online
Mahler, B.J., Woodside, M.D., VanMetre, P.C., 2016, Coal-tar-based pavement sealcoat--Potential concerns for human health and aquatic life: U.S. Geological Survey Fact Sheet 2016-3017, 6 p. DOI: 10.3133/fs20163017 Available Online
Anderson, Jesse and Perry, Jim, 1999, Comparison of temporal trends in ambient and compliance trace element and PCB data in Pool 2 of the Mississippi River, 1985-95: Environmental Management, vol. 24, no. 4, p. 497-507. Available Online
Brown, L.R., 1997, Concentrations of chlorinated organic compounds in biota and bed sediment in streams of the San Joaquin Valley, California: Archives of Environmental Contamination and Toxicology, vol. 33, p. 357-368. Available Online
Bryson, Jeannie R., Wates, Michelle L., and Kleiss, Barbara A., 2001, Concentrations of organic compounds in bed sediment in the Mississippi Embayment Study Unit: Proceedings of the 31st Mississippi Water Resources Conference, April 10-11, 2001 Raymond, MS, p. 2-8.
Mahler, B.J., Van Metre, P.C., and Foreman, W.T., 2014, Concentrations of polycyclic aromatic hydrocarbons (PAHs) and azaarenes in runoff from coal-tar- and asphalt-sealcoated pavement: Environmental Pollution, 188, p. 81-87. doi: 10.1016/j.envpol.2014.01.008 Available Online
Kronholm, S. and Capel, P., 2012, Concentrations, Loads, and Yields of Organic Carbon in Streams of Agricultural Watersheds: Journal of Environmental Quality, v. 41, n. 6, p. 1874-1883. doi:10.2134/jeq2012.0045 Available Online
Mahler, B.J., Van Metre, P.C., Wilson, J.T., Guilfoyle, A.L., and Sunvison, M.W., 2006, Concentrations, loads, and yields of particle-associated contaminants in urban creeks, Austin, Texas, 1999-2004: U.S. Geological Survey Scientific Investigations Report 2006-5262, 107 p. Available Online
Lico, Michael S., and Pennington, R. Nyle, 1997, Concentrations, loads, and yields of potentially toxic constituents in irrigation-drain systems, Newlands Project area, Carson Desert, Nevada, Nov. 1994 - Oct. 1995: U.S. Geological Survey Water-Resources Investigations Report 97-4034, 58 p. Available Online
Van Metre, P.C., and Mahler, B.J., 2004, Contaminant trends in reservoir sediment cores as records of influent stream quality: Environmental Science and Technology, vol. 38, no. 11, p. 2978-2986. doi: 10.1021/es049859x Available Online
Mahler, B.J., and Van Metre, P.C., 2001, Contaminants associated with suspended sediment in urban streams in Austin, Texas: Proceedings of the Seventh Interagency Sedimentation Conference, vol. 2, VII, p. 41-48.
Nowell, L.H., Moran, P.W., Gilliom, R.J., Calhoun, D.L., Ingersoll, C.G., Kemble, N.E., Kuivila, K.M., Phillips, P.J., 2012, Contaminants in stream sediments from seven U.S. metropolitan areas: I. Distribution in relation to urbanization: Archives of Environmental Contamination and Toxicology (2013) vol. 64, p. 32-51. doi: 10.1007/s00244-012-9813-0 Available Online
Kemble, N.E., Hardesty, D.K., Ingersoll, C.G., Kunz, J.L., Sibley, P.K., Calhoun, D.L., Gilliom, R.J., Kuivila, K.M., Nowell, L.H., Moran, P.W., 2012, Contaminants in stream sediments from seven U.S. metropolitan areas: II. Sediment toxicity to the amphipod Hyalella azteca and the midge Chironomus dilutus: Archives of Environmental Contamination and Toxicology (2013), vol. 64, p. 52-64 doi: 10.1007/s00244-012-9815-y Available Online
Van Metre, P.C., and Mahler, B.J., 2010, Contribution of PAHs from coal-tar pavement sealcoat and other sources to 40 U.S. lakes: Science of the Total Environment, vol. 409, p. 334-344 doi: 10.1016/j.scitotenv.2010.08.014 Available Online
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Bonn, Bernadine A., 1998, Dioxins and furans in bed sediment and fish tissue of the Willamette Basin, Oregon, 1992-95: U.S. Geological Survey Water-Resources Investigations Report 97-4082-D, 12 p. Available Online
Stephens, Verlin C., and Deacon, Jeffrey R., 1998, Distribution and concentrations of selected organochlorine pesticides and PCB's in streambed sediment and whole-body fish in the Upper Colorado River Basin, 1995-96: U.S. Geological Survey Fact Sheet FS-167-97, 6 p. Available Online
Besse, R.E., Van Metre, P.C., and Wilson, J.T., 2005, Distribution and sources of polychlorinated biphenyls in Woods Inlet, Lake Worth, Fort Worth, Texas, 2003: U.S. Geological Survey Scientific Investigations Report 2005-5064, 40 p. Available Online
DeVivo, J.C., Frick, E.A., Hippe, D.J., and Buell, G.R., 1995, Effect of restricted phosphate detergent use and mandated upgrades at two wastewater-treatment facilities on water quality, metropolitan Atlanta, Georgia, 1988-93: in Hatcher, Kathryn J., ed. 1995 U.S. Geological Survey reprints from proceedings of the 1995 Georgia Water Resources Conference, April 11 and 12, 1995 The University of Georgia, Athens, Georgia, p. 20-22.
Wangsness, D.J., Frick, E.A., Buell, G.R., and DeVivo, J.C., 1994, Effect of the restricted use of phosphate detergent and upgraded wastewater-treatment facilities on water quality in the Chattahoochee River near Atlanta, Georgia: U.S. Geological Survey Open-File Report 94-99, 4 p. Available Online
Van Metre, P.C., Horowitz, A.J., Mahler, B.J., Foreman, W.T., Fuller, C.C., Burkhardt, M.R., Elrick, K.A., Furlong, E.T., Skrobialowski, S.C., Smith, J.J., Wilson, J.T., and Zaugg, S.D., 2006, Effects of Hurricanes Katrina and Rita on the chemistry of bottom sediments in Lake Pontchartrain, Louisiana, USA: Environmental Science and Technology, vol. 40, no. 22, p. 6894-6902. doi: 10.1021/es060933g Available Online
Mahler, B.J., and Van Metre, P.C., 2001, Effects of Oil and Gas Production on Lake Meredith Sediments, 1964-99: U.S. Geological Survey Fact Sheet 072-01, 6 p. Available Online
Evaldi, R.D., and Kipp, J.A., 1991, Effects of oil production on water resources in the Kentucky River Basin, Kentucky: U.S. Geological Survey Water-Resources Investigation Report 90-4191, 58 p. Available Online
Sprague, L.A., Zuellig, R.E., and Dupree, J.A., 2006, Effects of urban development on stream ecosystems along the Front Range of the Rocky Mountains, Colorado and Wyoming: U.S. Geological Survey Fact Sheet 2006-3083, 4 p. Available Online
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Lura Price Fox, age 97, of the Clarks Creek Community passed away Monday morning, August 25th, 2014, at Cannon Memorial Hospital in Linville.
Born January 16, 1917 in the Creston Community of Ashe County, Lura was a daughter of the late Milburn Franklin and Eugena Molonia Roark Price. Mrs. Fox was baptized at Rock Creek Baptist Church in Creston and later joined and attended the Clarks Creek Seventh Day Adventist Church. She enjoyed her winter quilting, loved feeding the birds from her porch and tending to her annual flower gardens.
Mrs. Fox is survived twenty-seven nieces and nephews, including special friends & caregivers, Don & Sue Fox of Banner Elk, and long-time friend and physician, Dr. Alfred Earwood. She was preceded in death by her husband of 36 years, Loy Fox; three sisters, Ruth Roark, Ester Allen and Verta Griffin; and four brothers, Roea Price, Joe Price, infant twins; and a special niece, Alice Tweety. Following Mr. Foxs death, her constant companions were her faithful dogs and friends, Buddy #1 and Buddy #2.
Funeral services for Lura Price Fox will be conducted Sunday afternoon, August 31st, 2014, at 3 oclock, at the Austin & Barnes Funeral Chapel, officiated by Elder Mark Heisey and Elder Kenneth Hodges.
The family will receive friends Sunday afternoon from 2 until 3 oclock, prior to services, at Austin & Barnes. Burial will follow in the Fox Family Cemetery.
Memorials may be made to Gideons International, Boone Camp, Post Office Box 3602, Boone, NC 28607, or to the Banner Elk Seventh Day Adventist Church, 1551 Tynecastle Hwy, Banner Elk, NC 28604.
Online condolences may be shared with the Fox family at austinandbarnesfuneralhome.com
Austin & Barnes Funeral Home & Crematory is serving the Fox family.Funeral Homes


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On a stormy October evening, a letter, a late night trip to the library and a secret conversation lead Lily Evans to discover that there are several mysteries in her life that only she has the capability and the inclination to solve. The first mystery is James Potter – what could turn him from the arrogant, could-care-less boy that she had previously known to someone withdrawn and far away? Then, perhaps more troubling, there is Esther Collins, the fifth year who has vanished without a trace. Furthermore, one of Lily's best friends, Izza, is seeing a mystery boy and Lily is determined to know who.
Then there is the threat of war, backstabbing friends and NEWT's. A disinherited and emotionally battered Sirius Black is the source of heartache for his friends, except perhaps Izza, who, with her own terrifying family, might just understand him. Lily's closest male friend, Remus Lupin, is hiding a dangerous secret from her. Peter's girlfriend is screwing him over, and the whole time Lily is struggling to stop the people she loves from coming apart at the seams.
Please put me out of my misery and update this. It is an amazing story. It helped bring me out of a dark place. AND OMFG A STARKID QUOTE. Izza is canon to me now. I MUST KNoW MORE. I shouted out 'no' when I realised that tgis was the last chapter, so loud that my mum came running in and asked what was wrong. This deserves to be on every books shelf. Thank you for it


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Ocean County Gas Prices Up
Unrest a half a world away is causing prices to escalate at the gas pumps around Ocean County.
The price at the pump is up more than 11 cents a gallon in the past week at $3.26, according to the Chicago-based Gas Buddy organization. Analysts cite Iran's threat to close the Strait Of Hormuz – a vital oil shipping lane. The national average is $3.34, up about 8 cents.
|Lowest Gas Prices in Toms River
|Toms River Gas Prices provided by GasBuddy.com


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[Date Index]
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Re: Help required on differential equation
In article <DDDr09.AzA at wri.com> Dr Brian Hunton tel 270502 <hunton at news.ox.ac.uk> writes:
> Please help! I have a differential equation that I solve numerically with
> Mathematica. This gives me my interpolating function f[x] which I can happily
> plot. Now I want to plot f''[x] over the same range, but I'm having all sorts
> of bother. Can anyone help? I'd be very grateful...
In principle this should cause no problem. For example, if I define sol by
sol = NDSolve[{y'[x] == y[x],y[0] == 1},y,{x,0,1}]
{{y -> InterpolatingFunction[{0., 1.}, <>]}}
Plot[Evaluate[y[x] /. sol[[1]]],{x,0,1}]
Plot[Evaluate[y''[x] /. sol[[1]]],{x,0,1}]
work equally well (and give basically the same plot in this case).
Note the Evaluate, however. In the first one, the plot can be done,
but will take a little longer without the Evaluate. For the second
derivative, the plot will take MUCH longer without the Evaluate. This
is because, since Plot has the attributew HoldAll, y'' is evaluated
for each numerical value plotted, and it takes a significant amout of
time to compute the derivative of an InterpolatingFunction object.
If you prefer not to need to remember to put an Evaluate in your Plot
commands, an equally effective alternative is to compute in advance.
FOr sol as defined above, I could produce the smae plots by:
f = sol[[1,1,2]];
fpp = f'';
Rob Knapp


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Around the World
Iran to Build Two More Nuclear Plants - Washington Free Beacon
Iranian officials announced the upcoming construction of two new nuclear plants on Saturday, just hours before the United States and Western nations signed a nuclear pact that will allow Iran to continue enriching uranium, the key component in a nuclear weapon.
Kerry defends Iran deal: 'It's not a question of trust' - Washington Times
The Obama administration put on a full-court press Sunday to defend the deal the U.S. and key allies struck to try to halt Iran's burgeoning nuclear program -- but the White House faces a tough sell with members of Congress who criticized the terms and said they'll still press for even tighter sanctions on the Islamic republic.
Saudi prince to Iran: We won't sit idly by - Times of Israel
In an acerbic interview shortly before the Geneva interim deal was signed, a senior Saudi diplomat issued a rare direct threat to Iran, warning that "all options are available" should the international community fail to rein in Iran's alleged drive to acquire nuclear weapons.
Syria: Clashes to break siege kill over 160 in 48 hours - Times of Israel
Heavy clashes between Syrian troops and rebels trying to break a government siege in the suburbs of Damascus have killed at least 160 fighters over two days, activists said Sunday.
US hails accord with Iran as 'good deal' - Jerusalem Post
Hard negotiations in Geneva over Iran's nuclear program produced just the interim deal sought by US President Barack Obama: A six-month freeze to a crisis that threatened to dominate the rest of his presidency.
Secret direct US-Iran talks preceded deal in Geneva - Jerusalem Post
A series of private, bilateral meetings between US and Iranian officials preceded public rapprochement between the two nations, Obama administration officials acknowledged on Saturday night.
Israel-Palestinian Conflict
Officals: Israelis in secret trip to inspect Saudi bases - WND
Israeli personnel in recent days were in Saudi Arabia to inspect bases that could be used as a staging ground to launch attacks against Iran, according to informed Egyptian intelligence officials.
Obama briefs Netanyahu on Iran deal, says US committed to Israel's security - Times of Israel
US President Barack Obama called Prime Minister Benjamin Netanyahu Sunday evening, in a pre-scheduled conversation, and told him that the US will remain committed to Israel and its safety. The call came nearly 24 hours after Iran and world powers signed a first-step agreement in Geneva to largely freeze Iran's nuclear program in exchange for partial sanctions relief.
Netanyahu calls Iranian deal 'historic mistake' - Ynet News
At the beginning of the government's weekly meeting, Prime Minister Benjamin Netanyahu slammed the interim agreement reached Sunday between world powers and Iran in Geneva.
Inside the United States
Sticker shock hits health exchange shoppers - USA Today
Sweeping differences in health care exchange pricing among states and counties is leading to sticker shock for some middle-class consumers and others who aren't eligible for subsidies under the Affordable Care Act.
Price of Electricity Hit Record for October; Up 42% in Decade - CNS News
The price of electricity hit a record for the month of October, according to data released Wednesday by the Bureau of Labor Statistics. That made October the eleventh straight month when the average price of electricity hit or matched the record level for that month.
U.S. generals now take action to watch Obama - WND
After one of them called for the "forced resignations" of President Obama and congressional leaders in response to multiple grievances, including the alleged political purge of hundreds of senior military officers, two retired U.S. generals are creating a citizens' commission to scrutinize Obama administration actions on national security and economic issues.
N.S.A. Report Outlined Goals for More Power - NY Times
Officials at the National Security Agency, intent on maintaining its dominance in intelligence collection, pledged last year to push to expand its surveillance powers, according to a top-secret strategy document.
US banks warn Fed interest cut could force them to charge depositors - Financial Times
Leading US banks have warned that they could start charging companies and consumers for deposits if the US Federal Reserve cuts the interest it pays on bank reserves.
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Analysis & Opinions - The New York Times
When the War Ends, Start to Worry
The author refers to a "study on smuggling that was published by Harvard's Belfer Center for Science and International Affairs" in this op-ed. The study is 100 Grams (and Counting...): Notes from the Nuclear Underworld.
"When the War Ends, Start to Worry" was reprinted in the International Herald Tribune on August 17, 2008.
EVEN as Russia and Georgia continue their on-again, off-again struggle over South Ossetia and Abkhazia, a frenzied tea-leaf reading about the war's global political ramifications has broken out across airwaves and think-tank forums. But as the situation on the ground recedes inevitably to some new form of the pernicious "frozen conflict" that has plagued the region since Georgia's civil wars of the early 1990s, few are paying attention to a less portentous but equally critical international threat: an increase in the longstanding, rampant criminality in the conflict zones that is likely to further destabilize the entire Caucasus region and at worst provide terrorist groups with the nuclear material they have long craved.
While the Russian "peacekeepers" who entrenched themselves in the conflict zones in the 1990s (and who will now likely resume their posts anew) have proved ineffectual and uninterested in maintaining stability, they've been highly successful in protecting an array of sophisticated criminal networks stretching from Russia through Georgian territory. South Ossetia, in particular, is a nest of organized crime. It is a marketplace for a variety of contraband, from fuel to cigarettes, wheat flour, hard drugs, weapons, people and, recently, counterfeit United States $100 bills "minted" at a press inside the conflict zone.
"It's a pretty sophisticated counterfeiting piece," the American ambassador to Georgia, John Tefft, told me when I was in Georgia last year. He added that the fake bills appear so authentic that, if you weren't specifically looking for a forgery, you'd easily miss it. More than $20 million worth have been found up and down the East Coast of the United States as well as in Israel, Russia and Georgia.
"We know where the printing press is," Shota Utiashvili, a chief intelligence analyst at Georgia's Interior Ministry, told me last year, when I was researching a study on smuggling that was published by Harvard's Belfer Center for Science and International Affairs. "We know the channels of distribution. And we know who is running the business. But the problem is neither we nor the Americans can do anything because the place is under the protection of the Russian military." I found this sentiment echoed in my discussions at the American Embassy.
Far more dangerous contraband than fake bills is bartered in the conflict zones. On a bleak winter day last year, I hitched a ride from Tbilisi, the capital, to the "administrative border" — the semiporous line of control that swoops deep into Georgian territory from the Russian border demarking the contours of South Ossetia. I was investigating one of the most serious nuclear smuggling incidents in years — an offer of up to 3 kilograms of bomb-grade highly enriched uranium.
Because South Ossetia is within Georgia's internationally recognized borders, Georgia doesn't recognize the South Ossetian periphery as a legitimate frontier, and has thus refused to post border guards or impose any normal controls at the administrative line. At the grim little checkpoint, I had to navigate through dozens of armed young men, clad in seemingly random combinations of camouflage, none bearing the insignia of a national force (the scariest kind of border to cross, as there's no way of telling who's who).
Aside from demanding bribes from journalists, these South Ossetian irregulars, backed by the Russian peacekeepers, have long prevented Georgian forces from getting anywhere near the actual border — a two-lane hole called the Roki Tunnel that plunges into a mountainside on the Russian side of the border, cuts through two miles of bedrock beneath the Caucasus Mountains and pops out in South Ossetia, smack in the war zone.
Three years ago, Georgian intelligence officials began receiving reports from South Ossetian criminal contacts that a Russian smuggler — a North Ossetian calling himself Oleg — was circulating in Tskhinvali, the South Ossetian capital. He was reportedly looking for a buyer for what he claimed was high-quality enriched uranium pilfered from the Russian military. The price was $1 million for the initial shipment: 100 grams at $10,000 per gram. If the deal went well, a mother lode of up to 3 kilograms would be made available. One hundred grams of highly enriched uranium is not enough to build a nuclear bomb -- it's thought that even a top-tier terrorist group would require at least 15 kilograms -- but it would be a step in the right direction.
Huge international efforts sponsored by the United States State, Energy and Defense Departments have sought to counter such nuclear smuggling (since 1994, the Energy Department has spent upwards of $420 million installing nuclear detection equipment at international border crossings, most of that effort concentrated on Russia's frontiers), but conflict zones like South Ossetia have been an Achilles' heel.
In this case, we got lucky. A haphazard sting operation run by Georgian paramilitaries and Interior Ministry agents recovered the 100 grams of highly enriched uranium and captured Oleg Khinsagov, the Russian smuggler, and three Georgian associates. Testing of the material proved it to be nearly 90 percent pure — bomb-grade uranium indeed — sending secure telephone lines ringing from Washington to Langley, Va.
The Russian government refused to acknowledge the obvious — that the uranium had originated in Russia — so a quickly assembled team of American experts from the Energy Department and the F.B.I. loaded an unmarked jet and quietly raced to Tbilisi to secure the material.
Good police work is vital, but we simply cannot depend on dramatic interventions like the Georgian raid to combat the broad security threats posed by anarchy on Russia's borders. There are some great examples of cooperation between Washington and Moscow — the setting up of nuclear detection programs at borders is clearly one of them. Somehow, however, the full spirit of cooperation has yet to reach to the top of Russia's government — the same men, unfortunately, who seem more inclined to pouring fuel on the fire in Georgia.
Michael Bronner is an investigative journalist and filmmaker.
Want to Read More?The full text of this publication is available at the original publication source.
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Why You Should Love Those Weird Lettucesby Robin Miller in Uncategorized, July 15, 2013
These days, there are more than 100 varieties of lettuce available, giving us an endless assortment of colors, textures and shapes to adorn our plates — and countless ways to work more healthy greens into our diets. (Read more here about creative uses for leafy greens.)
In addition to traditional lettuces, unique, heirloom varieties are often offered at farmers' markets, and they're definitely worth a try. Don't be shy: When perusing lettuce, ask questions such as, "Is this lettuce more like a buttery Bibb or sharp arugula?" The grower will love bragging about the taste and textural qualities of the leaves!
And for those times when you don't have the opportunity to ask, use this cheat sheet!
Butter Oak: Varieties include Flashy and Blushed; the oak-shaped, super soft leaves are achieved by crossing butterhead-type lettuce with oak leaf lettuce.
Buttercrunch: Bibb-type lettuce with thick, juicy leaves and subtle buttery flavor.
Cimarron: Large, tender, red romaine with orange-yellow center; flavor resembles blend of red lettuce and romaine.


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Over 530 pages of video game comic strips!
What happens after the lights and machines are turned off and the doors are locked? At the arcade, strange things happen. Characters from video games get together. They talk and joke and have fun. This website is dedicated to what happens when the games are turned off. This is the Arcade After Dark!
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The story of the bar where all game characters go.
What happens when two game characters can't get work? They mock other video games of course.
What are video game characters really thinking? Find out!
Two teenage boys, one who likes modern games and one who likes classic games, make fun of each others games.
The psychiatrist who helps video game characters with their problems.
Various artwork you can use in your comic strips.
The story of a group of video game characters and what they do after the doors are locked.


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Made for all types of regular duty. Easy to open and close and suitable for close quarters clamping with a 2-1/2 in clamping reach from edge of bar to center line of screw. 1/4 in x 3/4 in plated, round edge, high carbon steel bars with 100,00 lbs., psi tensilestrength. 3/8 in cold drawn steel screws with smoothly cut U.S.S. threads. Malleable and/or ductile iron; powder coated orange finish castings. Multiple-Disc-Clutch design; 3/4 in diameter swivel with steel internal tooth washers for positive 'stay on' power. Varnished hardwood handle. 600 pound load limit.
|30 in


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English Retreads Sidecar Pouch
You Know Anything Called a Sidecar Has To Be Cool
Insecure about your coolness? Pick up one of these little Sidecar device pouches by English Retreads, a company that crafts bags and accessories out of reclaimed truck inner tubes, and get the mojo flowing.
Not only are you supporting an environmentally conscious company that puts my pantry kitchen recycling bin to shame, but I like that I can't define the Sidecar as a camera, iPod, or cell phone case — it's lined and big enough to fit a few things in there. I'd attach it to my keys to run errands or pop it into my bag and keep my essentials together.


text:
WATERLOO, N.Y. (AP) — A quick-thinking soldier on leave is being credited with helping rescue passengers from a bus that burst into flames after it was struck from behind by a tractor-trailer on a New York highway.
The driver of the truck, 59-year-old Timothy Hume of Michigan, was killed and 30 people injured.
Police say Sgt. Jacob Perkins of the 10th Mountain Division at nearby Fort Drum came was traveling behind the bus when it was hit about 1:30 a.m. He and others helped evacuate some of the 53 people aboard the bus.
Perkins had started his leave only 90 minutes earlier.
Police ticketed the bus driver, 52-year-old Rene Bisson of Welland, Ontario, for driving with a license that was suspended in New York because of speeding.


text:
He dropped out of school and worked as a butcher in the town of Nutley; her mother worked as a substitute teacher.
She was born into the humblest of Birmingham neighborhoods, to a mother who had been a butcher and a TV-salesman dad.
It is sold by the pound, cut to order, and presented not on a plate but on a sheet of butcher paper.
In the days that followed, Danny was bound, pistol-whipped, and, ultimately, slaughtered with a butcher's knife.
As the man started screaming, the 17-year-old butcher stepped between his pointing finger and the girls and took the death curse.
Thompson kept one of the stores, while Cleveland was proprietor of the butcher shop.
Just how do I profit, please, if I butcher myself to make your Roman holiday?
In December following, he and another person robbed a butcher on horseback, on the road coming from Hampstead.
It was said, a few years ago, that a Plantagenet was a butcher in a suburb of London.
The market for butcher's meat is almost everywhere confined to the country which produces it.
c.1300, from Anglo-French boucher, from Old French bochier "butcher, executioner" (12c., Modern French boucher), probably literally "slaughterer of goats," from bouc "male goat," from Frankish *bukk or some other Germanic source (see buck (n.1)) or Celtic *bukkos "he-goat." Figurative sense of "brutal murderer" is attested from 1520s. Butcher-knife attested from 18c. Related: Butcherly.
1560s, from butcher (n.). Related: Butchered; butchering. Re-nouned 1640s as butcherer.
"tough youth," 1902, first attested in nickname of U.S. outlaw George Cassidy (1866-?), probably an abbreviation of butcher (n.). Sense of "aggressive lesbian" is 1940s.
To do crudely and clumsily what should be done with finesse: I butcher their language/ I try to paint but butcher the canvas (1640s+)