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Osprey, D-backs extend affiliation
Missoula club's pact with Arizona now runs through 2020
By Missoula Osprey | July 16, 2014 2:00 PM ET
MISSOULA, Mont. -- The Missoula Osprey and Arizona Diamondbacks have announced today that the two have agreed upon a four-year extension of their current Player Development Contract (PDC), which will keep the two teams affiliated until at least through the 2020 season. The current agreement is set to expire at the end of the 2016 season.
This affiliation relationship is the second longest current consecutive tenure in the Pioneer League behind only the Billings Mustangs and Cincinnati Reds affiliation agreement. The Osprey franchise, which moved to Missoula from Lethbridge, Alberta in 1999, has been affiliated with the D-backs since the 1996 season -- one year before Arizona began to play Major League Baseball as an expansion franchise.
"The Osprey and Diamondbacks have a very strong partnership. We share philosophies of developing quality players on and off the field and the importance of community involvement through our players and franchises," explained Matt Ellis, Osprey Executive Vice President. "We feel that given the entirety of the relationship, that we have the best Major League affiliate partner in baseball for our franchise, our fans, and our community. Knowing and believing that fact makes extending early not only ideal but a priority for our franchise. We are proud of our long-standing relationship with the Diamondbacks and look forward to continuing this relationship through the rest of the decade."
Over the years, the Missoula Osprey and Arizona Diamondbacks have combined to develop 45 former Osprey players into Major League ballplayers. Some the of the current stars playing in the Major Leagues that wore an Osprey uniform include: Paul Goldschmidt (Arizona), Chris Owings (Arizona), Miguel Montero (Arizona), Gerardo Parra (Arizona), Chase Anderson (Arizona), Ender Inciarte (Arizona), Eury De La Rosa (Arizona), Carlos Gonzalez (Colorado), Jorge De La Rosa (Colorado), Emilio Bonifacio (Cubs), Lyle Overbay (Milwaukee), Bryan Shaw (Cleveland), Adam Eaton (White Sox), Sergio Santos (Toronto), Scott Hairston (Washington) and Jarrod Parker (Oakland).
"The Arizona Diamondbacks are thrilled to extend our PDC with the Missoula Osprey," said Mike Bell, Director of Player Development for the Arizona Diamondbacks. "It is important for us to partner with affiliates that understand development and care about our players. The Ellis family understands the game and knows how to create a perfect development environment. Furthermore, the fans in Missoula are knowledgeable and supportive of our young players and are a major reason we were quick to extend our PDC. Osprey alumni speak of their experience in Missoula for the rest of their careers. We would like to thank the community for making us feel so welcome."
On the field, the Missoula Osprey have won the Pioneer League Championship three times (1999, 2006, & 2012) and have made the playoffs six times, including three of the last five seasons.
The Osprey return home today, Wednesday July 16 to open a seven game homestand -- three games against the Grand Junction Rockies followed by four games against the Orem Owlz. There are lots of hot promotions remaining this season. For more on promotions please visit MissoulaOsprey.com. Tickets are available at the MSO Hub Box Office, located at 140 North Higgins in Downtown Missoula, online at MissoulaOsprey.com and by phone (406) 543-3300.
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|Harboth Redacre
|Hiram Kell
|Ander Jotum
|Ernest Kalthet
"Hmm, rats. That's seems kinda mundane though. There's got to be more interesting stuff down here..." Ernest mutters to himself. "I mean, goblins are dangerous and all, but they're so commonplace." He turns his head to gaze down at the Professor, whom is still visibly upset about not attaining his prize yet. Erenst doesn't seem to notice, however and continues his "conversation." "Open ANY chronicle that happens ANYWHERE within a stone's throw from Varisia, and I bet you platinums to pastries that there's at least one Goblin in there! Now... you know what I bet we'll find down here?" he asks (almost) rhetorically, as he turns his sights to the ceiling.
"Some kind of weird animal. I know my great-great-great grandfather briefly mentions the nobility of the time spending exorbitant amounts of gold on extravagant pets and simply releasing them when they grew tired of them. He personally ran from at least two tigers and a gorilla once." He snaps his head back forward and slams his fist into his open palm. "And I bet that there's nature shamans down here, attempting to preserve the wildlife below such a civilized area!"
"I wonder if they'll be friendly or not. Or even have clothes. Ha, with any luck, it'll be a tale akin to Among the Living. I think they finally got that into theatrical production."
|GM Helaman
The group sets of down and though the tunnels... The human woman Xene and the halfling woman named Piria seem to be the only cultists privy to the Vault's location. They navigate the catacombs from memory, often counseling one another privately when unsure which way to go. More than once they double back after reaching a dead end, evidence that their knowledge of the tunnel systems is not perfect.
Is anyone doing anything, attempting anything etc?
|9 Eyes Dragon
Disheartened at the pickled indecisiveness of Piria and Xene, the oracle questions to the party.
Does anyone have a clue exactly where we may be currently under the city? We need some sort of map to allay the possibility of getting lost in these catacombs. I didn't realize how expansive these passages are becoming. Please, can anyone guess where, in respect to the city above, we are?
In a very reduced tone, he speaks in Orc to Harboth.
Do I remember coming across an exit?
|Ander Jotum
|GM Helaman
9 Eyes and Harboth Only
Make me a series of 3 perception checks each. What you are doing is looking for tunnels up as you ramble through the catacombs, but these will need some time to find them and will delay the trip a bit. 9 Eyes, you've already made one but failed to hit the DC for the first. After this round of three (which you can aid another on if need be) I'll give you one more round of checks later. You'll need 3 successes. That said? No reason why you can't convince the group to also help you look for tunnels. This would give you more checks.
|Urthain Shardspear
Ur walks silently, listening to Earnests seemingly constant stream of words as he tries to remember all the twists and turns of the catacombs.
" If there are any Shamans down here I would not expect them to be naked and they should be friendly enough at least to me. "
|9 Eyes Dragon
Oracle implores that the Sarenites keep their eyes out for alternate routes of escape as a safety measure.
Followers of Sarenrae, aid in me finding any doors leading to the surface as we traverse these tunnels. However, don't open anything. If your pursuers are resilient enough, then they may be searching Oppara's underbelly through the same way. So, let us move carefully...and be our eyes and our ears to ensure wary travel.
I ask the same of you, brothers!
Perception/Scent: 1d20 + 11 ⇒ (3) + 11 = 14
Perception/Scent: 1d20 + 11 ⇒ (3) + 11 = 14
|GM Helaman
|Ernest Kalthet
Ernest asks, "Now, you said the whole way to the surface, right?"
Aid Another attempt 1 from Ernest: 1d20 + 3 ⇒ (14) + 3 = 17
Aid Another attempt 2 from Ernest: 1d20 + 3 ⇒ (19) + 3 = 22
Aid Another attempt 3 from Ernest: 1d20 + 3 ⇒ (15) + 3 = 18
Aid Another attempt 1 from Snouts: 1d20 + 3 ⇒ (19) + 3 = 22
Aid Another attempt 2 from Snouts: 1d20 + 3 ⇒ (3) + 3 = 6
Aid Another attempt 3 from Snouts: 1d20 + 3 ⇒ (11) + 3 = 14
|Hiram Kell
|Ander Jotum
Ander, hearing what the Oracle says and observing Urthain's actions, smacks his palm to forehead. I have been so stupid. He reaches into his belt pouch and removes a piece of chalk and begins to periodically inscribe small, discrete Pathfinder symbols high on the tunnel walls, describing what direction they have come from. He also continues to keep his eyes open for any signs of exits or the sanctuary.
Percept.1d20 + 7 ⇒ (4) + 7 = 11
Percept.1d20 + 7 ⇒ (10) + 7 = 17
Percept.1d20 + 7 ⇒ (18) + 7 = 25
|Harboth Redacre
Harboth keeps his eyes out for exits or the sanctuary.
perception: 1d20 + 9 ⇒ (2) + 9 = 11
perception: 1d20 + 9 ⇒ (6) + 9 = 15
perception: 1d20 + 9 ⇒ (3) + 9 = 12
|Zantir Mendoza
I would like to point out that being lost down here is quite a bit safer than being lost up there. We don't have the city guard after us down here.
|Ernest Kalthet
I would like to point out that being lost down here is quite a bit safer than being lost up there. We don't have the city guard after us down here.
"See, but there's more danger than just guards here. These are ruins, which are prone to collapse. If, by some chance, we collapse the entire district, the doorways and, especially stone gateways, are the most likely structure to keep standing. Plus, they may very well become our sole way out," Ernest states as-a-matter-of-fact-ly, ignoring all grammatical rules of run-on sentences.
"In fact, this building here could be EASILY taken down, given a good thwack on this banister here..." he points out, as he pats an awning's good remaining pole.
|GM Helaman
Between all of you trying to find exits heading up to the streets you locate three, and make a visual and locational reference for each. It takes over an hour, perhaps even two or more (as its definitely early evening when you find the third).
The Sarenites are eager to find the Vault and you move back into the tunnels. You continue through the darkness, and it seems the Dawnflower Blossoms are seeing some familiar tunnels.
I would like to point out that being lost down here is quite a bit safer than being lost up there. We don't have the city guard after us down here.
Its at that point that I'll roll initiative.
Buuuuuuuuuuut first I'll have perception checks.
Those who succeed DC15 (no Scent)
You notice a decrease in small vermin and an increase in cobwebs
Those who succeeded can make a SECOND Check - DC14.
DM Rolls
Stealth 1d20 + 8 ⇒ (6) + 8 = 14
Then I'll roll initiatives...
Anders + 5 1d20 + 5 ⇒ (17) + 5 = 22
Harboth + 2 1d20 + 2 ⇒ (6) + 2 = 8
Zantir + 8 1d20 + 8 ⇒ (11) + 8 = 19
Hiram + 4 1d20 + 4 ⇒ (17) + 4 = 21
Urthain + 2 1d20 + 2 ⇒ (1) + 2 = 3
Ernest + 0 1d20 + 0 ⇒ (9) + 0 = 9
Oracle - 1 1d20 - 1 ⇒ (4) - 1 = 3
GM Thingy +3 1d20 + 3 ⇒ (5) + 3 = 8
|Urthain Shardspear
2nd roll 1d20 + 8 ⇒ (16) + 8 = 24
|Zantir Mendoza
Perception: 1d20 + 5 ⇒ (4) + 5 = 9
I don't see it!
For future reference GM, it's quicker if you make these kind of checks for the whole party. Then we can get to the action quicker!
|9 Eyes Dragon
Those who succeed DC15 (no Scent)
Are you referring to any of the Perception rolls made? Or all of them? Or just the first Perception roll?
Noise ahead? Something moving. There's something nearby! ARM YOURSELF!
The oracle takes a defensive posture and arms his flail. Then calls out to Harboth in Orc. Harboth! funny
|GM Helaman
|GM Helaman
|Ander Jotum
|GM Helaman
|Ernest Kalthet
Ernest Perception 1: 1d20 + 1 + 2 ⇒ (7) + 1 + 2 = 10
Snouts Perception: 1d20 + 1 + 2 ⇒ (5) + 1 + 2 = 8
"Oh, curses!" Ernest yells in a surprised panic. He jumps back from the building he believes he almost knocked down. "No... I think we're good." He then examines the structure deeply. Snouts appears to be at his breaking point, having not eaten for at least an hour.
|Hiram Kell
|9 Eyes Dragon
The half-orc oracle's eyes roll back into his head and mutters a Mwangi witch doctor incantation. The absence of rats and abundance of webs has made the oracle take the precaution of determining if poisonous spiders are present. He casts detect magic in a 5-ft. cube, 25 ft. repeatedly, until he deems the area safe or encounter anything out of the ordinary.
Web. Spiders? Giant Spiders? Poison?
|GM Helaman
|9 Eyes Dragon
|GM Helaman
Moving ahead...
9 Eyes 2nd perception check 1d20 + 11 ⇒ (7) + 11 = 18
Urthain 2nd perception check 1d20 + 8 ⇒ (12) + 8 = 20
The marching order was thus...
Harboth, 9 Eyes
Zantir, Pilria
Urthain, Ernest
Saren, Snouts
Saren, Saren
Hiram, Ander.
The Pathfinders and their wards move through the darkened tunnels - several of you noticing the increase in webs and the decrease in rats and other vermin.
The corridor widens ahead for a brief while before looking like it narrows again.
The Oracles keen scent warns him as the scent of something wafts from a collapsed section in the walls, hard to spot in the dim light... but not quick enough to allow him to pull back. Unlike his companion his senses are enough to put him on guard. Urthain also is aware enough of his surroundings and likely denizens that he too is ready.
Ok - Anyone who beat Perception 15 on two rolls gets to make a standard action ONLY during the surprise round (unless you have traits/feats that help). If I have sodded you up let me know
Characters NOT on the map can move onto the map next round if surprised. I deliberately made the map 3 squares wide to allow for movement instead of clogging everything up and not giving anyone other than the front two a chance to shine.
Initiatives (Surprise round)
Anders + 5 1d20 + 5 ⇒ (17) + 5 = 22 Surprised (off board)
Hiram + 4 1d20 + 4 ⇒ (17) + 4 = 21 (off board)
Zantir + 8 1d20 + 8 ⇒ (11) + 8 = 19 - Surprised
Ernest + 0 1d20 + 0 ⇒ (9) + 0 = 9 - Surprised
GM Thingy +3 1d20 + 3 ⇒ (5) + 3 = 8 Hehehe!
Harboth + 2 1d20 + 2 ⇒ (6) + 2 = 8 - Surprised
Urthain + 2 1d20 + 2 ⇒ (1) + 2 = 3 - Can Act
Oracle - 1 1d20 - 1 ⇒ (4) - 1 = 3 - Can Act
Piria moves off the map at the end of the round and players should feel free to occupy her space.
The spider, something that looks like a massive Funnel Web spider, darts from the tunnel...
GM Stuff
(1-2 9 Eyes, 3-6 Harboth) Giving Harboth an edge due to the spider likely trying to eat the most vulnerable and spiders are good at that sort of thing.
1d6 ⇒ 4
... and attacks Harboth, who was looking the other way.
1d20 + 2 ⇒ (14) + 2 = 16 vs flatfooted AC
1d6 ⇒ 4 damage and save (if necessary) vs Fort DC14 Poison.
As soon as I get Urthain and 9 Eyes + Hiram (moving onto the board - Count row A as the first square of your movement) I'll move to Round 1.
This map was not something provided by the scenario (they gave nothing at all) but is something I ginned up... IF I run this game again I'll move the spider hole further down the map but given that Hiram and Ander were playing rear guard? It works
MAPLINK on the Campaign Tab - sorry.
|Urthain Shardspear
|GM Helaman
|9 Eyes Dragon
Having seen Harboth bitten and can't cast without provoking from the spider, the oracle takes the offensive and will first try to shift to B4 and attack the spider with his flail.
If you try to perform CM trip, does it do damage as well? Or do you only get to knock the target prone if you're successful tripping? If I can do a trip and deal damage that's what I'd like to do on my surprise turn.
SPIDER! Exclaims the oracle to the party.
Flail damage: 1d8 + 1 ⇒ (3) + 1 = 4
|Ernest Kalthet
Tripping is an Combat Maneuver, which means it does not cause direct damage to a creature. Additionally, tripping (and any combat maneuver) provokes from the target if you do not have the feat "Improved **", with ** being the maneuver in question. The "Trip" tag on the flail means that if you fail by 5 or more, you can drop the weapon instead of getting tripped back. Additionally, this creature has 8 legs. The more legs something has, the harder it is to trip it. In all seriousness, your best bet is to try to just hit it with your pointy thing or full retreat and hope it doesn't have reach.
Is the spider on the ceiling, wall, or floor? Also (especially if ceiling), what's the tunnel height?
|Hiram Kell
|Harboth Redacre
Dag, missed some good stuff (and I think the chance to make those 2 perception rolls)!
Fort save: 1d20 + 4 ⇒ (13) + 4 = 17
Harboth, shaken from a daze by the spider's bite, rears back and roars at the beast. HAAOARGHH!
|GM Helaman
|Ernest Kalthet
Also, do you want me to roll my own ID rolls or will you? If it's mine, I'll preroll for my turn in my "in case I can't get to a comp on my turn" block.
Free: Kn(Na): 1d20 + 7 ⇒ (7) + 7 = 14 "It's a Vudrani Green Leaf Spider! Don't let it spit its acid at you!"
No Action: 5ft step into C0
Move: Draw Wand of Magic Missile (50 Charges)
Standard: Activate wand for 1d4 + 1 ⇒ (4) + 1 = 5 damage. 49/50 charges left.
Snouts: Double moves to stay behind me.
|Urthain Shardspear
|Hiram Kell
|Zantir Mendoza
Round 1:
Zantir brings his hammer to bear against the large, foul beast.
Attack: 1d20 + 5 ⇒ (10) + 5 = 15
Damage: 1d12 + 4 ⇒ (10) + 4 = 14
I can't see the map while I'm at work, but I should be able to swing at the spider with my Hammer, moving as needed or over an ally's head.
|Ander Jotum
I think Hiram and I go first.
Ander drops his backpack and moves to B4 and attacks spider with his rapier.
Attack: 1d20 + 3 ⇒ (3) + 3 = 6
Damage: 1d6 ⇒ 6
If I can also do a swift action, I'll expend 1 of my arcane pool to grant a +1 enhancement bonus
Not that it mattered
|Harboth Redacre
|GM Helaman
Everyone take a DEEEEEEEEEEEEEP breath. Wait. Its not the only monster you'll ever see, so gimme a chance to order things - when I call Round 1, act round 1. It also makes for better co-ordination.
9 Eyes swings hard but wildly at the spider, while Harboth roars at being bitten. Both Hiram and Urthain move around the outskirts of the battle, making room and creating options.
Round 1
Anders + 5 1d20 + 5 ⇒ (17) + 5 = 22 - Rushes in to B4... and misses with his weapon
* Hiram + 4 1d20 + 4 ⇒ (17) + 4 = 21
Zantir + 8 1d20 + 8 ⇒ (11) + 8 = 19 - Reaches through the gap with his polearm hammer and BLATS!! the Spider, which is looking very badly affected
* Ernest + 0 1d20 + 0 ⇒ (9) + 0 = 9 -
GM Thingy +3 1d20 + 3 ⇒ (5) + 3 = 8 Hehehe!
Harboth + 2 1d20 + 2 ⇒ (6) + 2 = 8 - Swings hard at the spider and smashes it to pulp.
Urthain + 2 1d20 + 2 ⇒ (1) + 2 = 3
Oracle - 1 1d20 - 1 ⇒ (4) - 1 = 3
This leaves Hiram and Ernest to act before the spider gets another attack.
|Hiram Kell
|GM Helaman
The spider dies... horribly.
There is no loot within the spiders lair, just dry web wrapped critters.
Post any healing etc you wish to attempt...
About an hour after the spider ambush, you and the Sarenite refugees finally reach the Vault of Sarenrae.
In the center of this large, natural cavern, easily more than forty feet in height, stands the ruin of a truly ancient temple constructed of chipped grey and white marble. Its domed roof collapsed long ago, but the structure is otherwise in remarkably good shape. Where doors must once have hung, a small campfire now burns, surrounded by piles of ragged but
neatly folded bedding.
Seven people sit huddled around the small campfire to ward off the damp and cold of the cavern. As soon as they spot the approaching party, they pick up wooden clubs and leap to their feet suspiciously.
|Urthain Shardspear
Seeing the spider managed to bite Harboth, Ur aproaches the Half Orc as they continue on " I have a kit with salves and bandages in my bag. I might be able to ease the pain of that bite if you let me have a look. "
When they reach the vault of Sarenrae Ur looks about the large cavern in awe especailly the ancient temple as the occupants grab weapons and stand Urthain attempts to look non threatening dropping his spear point to the floor.
|9 Eyes Dragon
Hold! We are friends of Sarenrae! Xene and Piria travel with us. No need to be alarmed! The half-orc oracle shouts into the air, as he cannot see past 30 feet. He tries to discern if the strangers are friends or foes, by hearing any religious banter or by detecting the familiar scent of a Sarenite from lit incense or the kind.
If Harboth is still wounded, the oracle bestows a cure light wounds spell on his half-orc companion.
Oracle asks Harboth in Orc tongue. Are these Sarenites, brother?
|GM Helaman
9 Eyes Dragon
Something... is a little off... think on it and maybe it will come to you. Could it be the room? The moldy sticks in the fire?
Piria calls out Well met by moonlight, sisters and brothers, but soon the dawn will come!.
Evidently this is some sort of coded greeting and the cultists relax. One of them comes forward and Piria relaxes. Akkuret! We are relieved to see you.
Akkuret is a slim, redheaded human man with pinched features. Evidently someone of some authority.
Religion DC15 shows him to wear the mantle used by Lay Ministers.
Akkuret invites the new arrivals into the ancient
temple, You have our thanks - be welcome here. Have you need of food? Drink? Sit and tell us of how you have come to help us Dawnflower Blossoms. He offers you seats in the recently constructed pews. All who want it are given food and wine.
While everyone, including the rescued Sarenites are eating and drinking, Ankkuret speaks. Maybe we can share information? I may have some pieces of the puzzle you are missing and it may be that you can help me better understand the situation we are in now.
More for you than anything else, I've put a new map up (See Campaign Info) but its assumed you are around the fire area for now.

subset: commoncrawl


text:
The Obamas reported an income of $1,728,096 for 2010, according to tax returns that were posted on the White House website Monday. They paid $453,770 in total federal taxes.
The majority of the family's income is from the proceeds of the sale of the president's books.
The president and first lady also reported donating $245,075—or about 14.2 percent of their adjusted gross income — to 36 different charities.
The largest reported charitable gift was $131,075 to the Fisher House Foundation. President Obama is donating the after-tax proceeds from his children's book to a Fisher House scholarship fund for children of fallen and disabled soldiers.
The president and first lady also released their Illinois income tax return and reported paying $51,568 in state income taxes.


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This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
Matrix metalloproteinases (MMPs) are a family of more than twenty five secreted and membrane-bound zinc-endopeptidases which can degrade extracellular matrix (ECM) components. They also play important roles in a variety of biological and pathological processes. Matrix metalloproteinase inhibitors (MMPIs) have been identified as potential therapeutic candidates for metastasis, arthritis, chronic inflammation and wrinkle formation. Up to present, more than 20,000 new compounds have been isolated from marine organisms, where considerable numbers of these naturally occurring derivatives are developed as potential candidates for pharmaceutical application. Eventhough the quantity of marine derived MMPIs is less when compare with the MMPIs derived from terrestrial materials, huge potential for bioactivity of these marine derived MMPIs has lead to large number of researches. Saccharoids, flavonoids and polyphones, fatty acids are the most important groups of MMPIs derived from marine natural products. In this review we focus on the progress of MMPIs from marine natural products.
Matrix metalloproteinases (MMPs) are a family of zinc-dependent endopeptidases that degrade extracellular matrix (ECM) components and play important roles in a variety of biological and pathological processes [
Generally MMPs consist of a propeptide domain having about 80 amino acids, a catalytic metalloproteinase domain of about 170 amino acids, a linker peptide of variable lengths (also called the "hinge region") and a hemopexin domain of about 200 amino acids [
MMPs' activities can be regulated by endogenous inhibitors, such as tissue inhibitors of metalloproteinase (TIMPs), α2-macroglobin, heparin and the reversion-inducing cysteine-rich protein with kazal motifs (RECK) [
Design and synthesis of MMPIs has gone through several stages of development over the past 20 years [
Clinical trials for the anti-cancer and anti-arthritis effects have been carried out using many early MMPIs. However, only a few MMPIs were effective (such as Marimastat, the overall survival rate of the gastric cancer and pancreatic cancer patients increase). Therefore they have not been used in the later stages of clinical trials. At present, only one MMPI (Periostat) is being used clinically for periodontitis therapy [
With intensive studies on MMPs, the MMPs host-cell defense functions and physiological functions have been discovered by researchers. The early MMPIs whether peptide inhibitors or small molecule inhibitors, their activities are most dependent on the Zn2+ chelating group and MMPs S1′ pocket combined group. However the Zn2+ chelating group also reduces these early MMPIs' selectivity. In addition, these early MMPIs inhibit some MMPs physiological functions and some other metalloprotease such as DPP III and leucine aminopeptidase, when they inhibit the abnormal MMPs in pathology situation [
To sum up the above arguments, the clinical trials of MMPIs in broad-spectrum, face the obstacle, as well as the normal physiological functions of MMPs should be further studied for the choice of drugs which are selectively acting on them for the MMPs relevant diseases. MMPs S1′ pocket determine the specificity of substrates and inhibitors in a large extent, therefore the S1′ pocket is very important for the design and synthesis of MMPIs. Design of MMPIs should be based on the unique functions of MMPs S1′ pocket, not only to increase the selectivity for this MMP, but also greatly reduce the inhibition of other class of metalloprotease such as ADAMs. At present, development of the new generation of MMPIs is guided by this idea. In addition, development of new type of MMPIs with different inhibiting mechanisms can increase the drugs' selectivity; which may play a key role in the treatment of various diseases related to MMPs [
Broadly speaking, the mechanisms of inhibiting the activity of MMPs include, direct inhibition of the enzymes, blocking the MMPs proenzyme activation, suppressing the synthesis of MMPs in the gene level, and so on. The MMPIs can be divided into four classes: the natural MMPIs secreted by tissues; synthetic MMPIs; MMPIs screened from natural products and the MMPIs screened from the phage display random peptide library and antibody library. The synthetic MMPIs and natural product derived MMPIs are the hot spots. In recent years, due to the synthetic small molecule inhibitors meet a variety of issues in clinical applications, more attention is given to the research of MMPIs derived from natural products.
Lots of successful research work have been conducted to identify MMPIs from land natural products, also got a lot of results. For instance, Kim
The marine saccharoid MMPIs are very popular among marine derived MMPIs area. The most of marine saccharoid MMPIs inhibit MMP by direct down-regulation of MMP-9 transcription or via inhibition of activator protein-1(AP-1) pathway or nuclear factor κB (NF-κB) pathway. Kim
Angiogenesis is involved in initiating and promoting several diseases such as cancer and cardiovascular events. Chen et al. obtained highly sulfated λ-carrageenan oligosaccharides (λ-CO) by carrageenan depolymerization. They have demonstrated that λ-carrageenan oligosaccharides could effectively inhibit angiogenesis in the CAM (chick chorioallantoic membrane) model and human umbilical vein endothelial cells (HUVECs). Significant inhibition of vessel growth was observed at 200 μg/pellet. A histochemistry assay also revealed a decrease of capillary plexus and connective tissue in λ-CO treated samples. λ-CO inhibited the viability of cells at the high concentration of 1 mg/mL, whereas it affected the cell survival slightly (>95%) at a low concentration (<250 μg/mL). Furthermore, the inhibitory action of λ-CO was also observed in the endothelial cell invasion and migration at relatively low concentrations (150 300 μg/mL), through down-regulation of intracellular matrix metalloproteinases (MMP-2) expression on endothelial cells. [
Fucoidan is a uniquely-structured sulfated polysaccharide found in the cell walls of several types of brown seaweed which has been recently evaluated for its bioactivities by Ye
Marine saccharoid MMPIs exhibit high MMPs inhibitory activity either by direct inhibition of the enzyme or by inhibiting the expression of MMPs. And also these marine saccharoid MMPIs have shown low toxicity levels. However, due to high molecular weight of theses MMPIs the structure-activity relationship and also the mechanism of the activities are hard to be addressed by the researchers. If these shortcomings are overcome in the future, marine saccharoid MMPIs have a great potential to be used in clinical applications.
Flavonoid glycosides, isorhamnetin 3-O-b-D-glucosides, and quercetin 3-O-b-D-glucoside were isolated from
The active compound from methanol extracts prepared from roots of
Matrix metalloproteinases (MMPs), a key component in photoaging of the skin due to exposure to ultraviolet A, appear to be increased by UV-irradiation-associated generation of reactive oxygen species (ROS). Ryu et al. demonstrates that the alga
In murine asthma model, Kim et al. observed that MMP-9 expression was significant reduced via the administration of
The compounds eckol, 2dieckol, 6,6′-bieckol and 1-(3′,5′-dihydroxyphenoxy) -7-(2″,4″,6″-trihydroxy-phenoxy)-2,4,9-trihydroxydibenzo-1,4,-dioxin were extracted from brown algae,
Flavonoids and polyphenols MMPIs have excellent MMPs inhibitory activities; however they show a high toxicity level. Therefore, the pharmaceutical applications of these MMPIs are limited. Researchers should pay attention to reduce their toxicity levels by altering the structure in a way by preserves it's bioactivity. Then this class of MMPIs will gain a huge potential to be used in clinical applications
Researchers have identified that the long-chain fatty acids could inhibit MMPs. however for different MMPs the degree of inhibition is different, such as oleic acid, elaidic acid can inhibit MMP-2 and MMP-9 with the micromol Ki values, although their inhibitory effects on collagenase-1 (MMP-1) are weak, as assessed using synthetic or natural substrates [
It is well known that the marine fishes are rich in omega-3 long-chain polyunsaturated fatty acids (ω3 LC-PUFAs), especially eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), which are active nutrients [
Acetylenic fatty acids isolated from marine sponges have exhibited wide range of biological activities such as cytotoxicity [
Shark cartilage extracts researches are very popular in recently [
Alkaloid Ageladine A extract from the marine sponge,
The Atlantic cod (Gadus morhua) muscle contains a 21-kDa proteinase inhibitor. The inhibitor had properties similar to human TIMP-2. The inhibitor was found to inhibit the gelatin-degrading enzymes present in the gelatin-bound fraction. In addition, it inhibited gelatinolytic activity obtained from a human macrophage cell medium rich in MMP-9 [
(+)-Aeroplysinin-1, an antibacterial brominated compound produced by certain sponges, was selected during a blind high-throughput screening as new potential antiangiogenic compounds obtained from marine organisms. The concentration of MMP-2 in the medium conditioned by aeroplysinin-treated cells was clearly lower than that in untreated cell medium. The MMP-2 bands in aeroplysinin-treated cell conditioned media were 60 + 4% compared to those of untreated cells, whereas extracts of treated cells yielded MMP-2 bands that were almost twofold (1.77 + 0.04) those of untreated cells. Thus, aeroplysinin-1 seems to affect mainly the release of MMP-2 to the medium [
The marine environment is characterized by high biodiversity offering vast variety of natural products which could be used as potential drugs, particularly in the area of cancer chemotherapy, such like the matrix metalloproteinase inhibitors. Therefore continuation of finding new leads in this area of extracting bioactivity compounds from marine natural products will make much sense.
MMPIs design and synthesis has been done for ages and has gone through several development stages. Although many of the synthetic inhibitors of MMPs showed good inhibitory activity, however, the compounds do not have an ideal MMPs selectivity, combined with others limitations such as the low oral bioavailability, unstable metabolism, biological toxicity, and also these inhibitors in clinical trials show excessive side effects. Due to these major shortcomings this type of MMPIs failed to be used as drugs [
With MMPIs finding of functionality of MMP's in normal physiology functions, the development of MMPIs entered a new period [
This research was supported by a grant (M2007-0) from Marine Bioprocess Research Center of the Marine Bio 21 Center funded by the Ministry of Land, Transport and Maritime, Republic of Korea.
matrix metalloproteinases
extracellular matrix
matrix metalloproteinase inhibitors
tissue inhibitors of metalloproteinase
reversion-inducing cysteine-rich protein with kazal motifs
a disintegrin and metalloproteinases
safety analysis report
human dermal fibroblasts
carboxylated chitooligosaccharides
sulfated glucosamine
nuclear factor κB
activator protein-1
λ-carrageenan oligosaccharides
human umbilical vein endothelial cells
sulfated S. maindroni ink polysaccharide
Ecklonia cava


text:
This rationale was popularized in 1974 when Gerald Ford explained why Richard Nixon -- who built his career as a "law-and-order" politician demanding harsh punishments and unforgiving prosecutions for ordinary criminals -- would never see the inside of a courtroom after being caught committing multiple felonies; his pardon was for the good not of Nixon, but for all of us. That was the same reasoning hauled out to justify immunity for officials of the National Security State who tortured and telecom giants who illegally spied on Americans (we need them to keep us safe and can't disrupt them with prosecutions), as well as the refusal to prosecute any Wall Street criminals for their fraud (prosecutions for these financial crimes would disrupt our collective economic recovery).
A new episode unveiled on Tuesday is one of the most vivid examples yet of this mentality. Over the last year, federal investigators found that one of the world's largest banks, HSBC, spent years committing serious crimes, involving money laundering for terrorists; "facilitat[ing] money laundering by Mexican drug cartels"; and "mov[ing] tainted money for Saudi banks tied to terrorist groups." Those investigations uncovered substantial evidence "that senior bank officials were complicit in the illegal activity." As but one example, "an HSBC executive at one point argued that the bank should continue working with the Saudi Al Rajhi bank, which has supported Al Qaeda."


text:
So long MSC ....: MSC Divina Cruise Review by ccna101
Overall Member Rating
So long MSC ....
Destination: Eastern Caribbean
Embarkation: Miami
Ship is fully booked.
Boarding was efficient: they do not allow to bring your favorite wines into the ship ( I knew).
Foods are just what we paid for, sub-par: creme brulee for MSC is custard with sugar on top !!! beside that, the rest of the foods are just decent, nothing to spoke for .
We purchased the 7 bottles for $155 at the table and they do have some decent wines.
Exercise room is ... miniature at its best: I was up there 6:45am, no treadmill, bikes, ... The 14-15 deck are constantly wet and slippery !!! the seven deck is my best keep secret for walk/running in between.
Clubs / Party are somewhat boring ... ( may be it is a good thing for our children!!! ).
Fellow passengers are mix... few p/p that we talked to are not happy about the food / services ...
I think the service crew are decent and quite More effective.
We are former MSC goers so we been invite to a free cocktail party, thanks MSC.
The sport equipment checkout location (basketball/soccer, pingpong ... ) is well disguise up-left-corner of 16 floor, near the Virtual Room: Why MSC ??!!
Day 3:
First port/ St Maarteen is excellent, we spend the whole day snorkeling ( which is may not be the best). Transport: walk outside of port $2/pp but inside $8/pp.... our friends pay $15/pp to the same destination. Good spot for shopping- prices.
Day 4:
St Juan: very hot and divided, old-St-Juan is about 10x10 blocks and have little to offer except some sign seeing and shopping. You should able to use your cell/ WIFI around the area for free. Trolley is free around the major spots within the area.
New St Juan is bigger and it is close to our time limit so we did not explore there .
Day 6:
Great Stirrup Cay: even hotter !!! holy macaroni ! numerous passengers pass out due to (heat stroke, fever, ... ) we have to pick up the tickets and wait to be boat to the island .... very crowded beach with little to offer !!! MCS serving burgger/ hog dog/ water ... but the whole place is cooked under the sun... I am glad that my kids survive this island but ... you been warned .
Day 7:
I need to catch a early fly out so I dug out at 7:45am with little crowd to contest ... again smooth sailing there. Make sure if you use the shuttle, have the cash or pay with cc in advance... don't believe what you heard on the phone ($15/pp for me to FLA )
Overall: I think if you do accept a lower standard and trade them off with low cost, MSC still is .
For me, it may be the last. Less
Published 08/18/14
Cabin review: 14xxx
Balcony cabin is spacious as expected: good size bed and roll-a-bed that can fit a couples and small child. Clean, we do smell a strong ammonia odor and the cleaning crew try but it still there until the last day, oh well.
Read Cruise Critic's MSC Divina Review >>
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text: Ritter asks state agencies to tighten belt By on June 27, 2009 By Jason Kosena THE COLORADO STATESMAN The state's budget problems continued to worsen this week. State economists told the Joint Budget Committee and the Governor's Office on Monday that Colorado is $249 million short for the 2008-'09 fiscal year, which ends on June 30, and is another $135 million behind in 2009-'10 fiscal year projections. […]This content is only available to subscribers. Login or Subscribe Share this:EmailTwitterFacebook Current News, Title Item


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|You are in: UK: England
Tuesday, 22 October, 2002, 17:16 GMT 18:16 UK
Stealth fighters on exercise in UK
American stealth fighter aircraft have arrived in Britain to take part in a training exercise, officials have revealed.
The four F-117A Nighthawk planes are at RAF Lakenheath in Suffolk for Operation Coronet Nighthawk.
On Tuesday, a United States Airforce spokesman said the two week exercise aims to give pilots and crews the chance to familiarise themselves with US operations in Europe.
The stealth fighters, from Holloman Air Force Base in New Mexico, fly at subsonic speeds and can avoid radar detection.
The spokesman said: "The deployment is giving them the opportunity of training in the European theatre that they do not receive in the US.
"This is something which is done in different theatres of operation on a regular basis and it is the first time in Europe since 1999."
See also:
17 Sep 02 | UK
Internet links:
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Top England stories now:
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text:
I sat on the bench with Kelly watching the moon rise over the intracoastal waters of Oak Island, the boys sleeping in the motel room about fifteen steps behind us, the Atlantic Ocean about 400 steps to the south, and I said, "I don't remember the last time I was so relaxed."
We took our first real family vacation last week. We got on an airplane at 5 a.m. last Monday and flew to Wilmington, North Carolina, then rented a car and drove to the beach. The boys wanted to go to the pool immediately, but we coaxed them onto the beach. When we crossed the walkway and they finally saw it they ran into the surf fully dressed, screaming.
We spent one day in Oriental with a college friend of Kelly's on their family sailboat.
We visited Southport and the ancient Live Oak trees.
But mostly we slept late, took turns walking on the beach, read books (nothing theological), watched too much Disney Channel (Kelly says he will not watch Hannah Montana ever again), swam in the pool and then in the ocean and then back again to the pool. We ate seafood (conch fritters, shrimp, grilled tuna, Calabash coated oysters and scallops) hush puppies, and sno cones. Our favorite restaurant, the Yacht Basin Provision Company, was so busy we had to wait outside on a dock, then huddled inside, in a thunderstorm, for an hour. The boys liked it so much we had to go back.
We hadn't gone on vacation like this before; the boys were too young. But it was time. I wanted us to have time together when I didn't have to say, "I'm too busy, I have to work, I have a meeting." Except at the airport we never had to hurry. And we saw the ocean, as much as we wanted.
I also needed some time away. It is hard to disengage from the church, hard to miss worship in this congregation, hard to miss a memorial service and training events, hard to not check in and make plans for the upcoming months. But even today the boys are adding "thanks for the vacation" to their prayers. And I remembered how to relax a little.
1 comment:
- Chris said...
Wow, Michelle! It's wonderful you got to do this and it sounds like you and Kelly did it just right. The boys will remember this trip always, I am sure.
I love NC, but haven't had the opportunity to spend much time on the coast. Now I want to go back, especially now that you've reminded me of the hushpuppies.
- August 11, 2009 8:08 AM
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text:
Ella's Run: Right to Hike's 6th Annual 5K and Fun Run
Gwinnett Environmental and Heritage Center
Sat 10/19/2013
1 mile, 5K, Trail
800 Participants
All competitors that register early will receive the 6th Annual Ella's Run t-shirt (late registration and "day of" only while supplies last) There will be prizes awarded to the top finishers for both men and women in various age groups. In celebrating the life of Meredith Hope Emerson, friends and family have founded Right to Hike, Inc., a non-profit organization that supports causes that were close to Meredith's heart, including hiking safety. Funds will be donated to purchase emergency solar/wireless phones for greenways, parks and trailheads, to help fund the Meredith Hope Emerson Award for Study Abroad at UGA, and to support animal rescues and microchipping. Mud Run 2013; while our interest and support in the Mud Run has been outstanding the last 2 year but due to budget constraints at the GEHC it is doubtful that we can support a mud run this year. We hope that you'll participate in the 5K (partial trail run) instead.
- Address:2020 Clean Water Dr
Buford, GA 30519


text:
Has anyone verified that the configuration generated for dhcp6s is
actually functional?
I did some poking and I don't think the configuration files that are
generated will actually work (I would need to verify this on another
box, though).
The relevant code seems to be the services_dhcp6s_configure() function
in /etc/inc/services.inc
For me, it generates something like the following:
option domain-name "soucy.org";
option domain-name-servers 2610:48:200:800:1:0:0:1;
interface sis1 {
preference 255;
address-pool poolsis1 7200 86400;
pool poolsis1 {
range 2610:48:200:800:1:0:0:64 to 2610:48:200:800:1:0:0:C7 ;
host m0n0wall {
duid 00:00:24:cc:08:2d;
address 2610:48:200:800:1:0:0:1 infinity;
From everything I can find online, though, I believe there are a few
errors: I think the pool information needs to be defined within an
interface definition; I think the prefix is likely required; and I
believe the range statement expects a / followed by the prefix size
for the 2nd address.
I've never configured dhcp6s before so I haven't verified any of this.
I'm willing to do some leg work and submit a change for it if nobody
is already working on it. I'd just like to know if it actually works
for others before I assume its the config that is the problem (could
also be an issue of not joining the correct mcast group to get the
Ray Soucy
Communications Specialist
+1 (207) 561-3526
Communications and Network Services
University of Maine System


text:
An exhibition exploring over 500 years of gardens, parks and open spaces in the borough opens next month.
Through objects, photogrpahs, films and documents, visitors will be able to see what medieval farmland in Redbridge looked like and take a look at 18th century Wanstead House.
Visitors will also be able to learn about the fight to preserve the ancient Hainault Forest and see how land in the borough has been used over the last 100 years.
The exhibition opens on March 5 in Redbridge Musuem in Redbridge Central Library in Clements Road, Ilford.
It is free to attend and runs until June 22.


text:
Federal Justice Minister Peter MacKay is calling on Rob Ford to get help after the Toronto mayor admitted publicly that he had smoked crack cocaine, an illegal drug.
But Mr. MacKay, whose Conservative government styles itself as tough on crime, declined to offer an opinion on whether Mr. Ford should step down. "That's not for me to say," he told reporters in Ottawa.
He also rebuffed a question on whether the Toronto politician should be charged.
"Clearly, those are matters for the provincial police force," he said. "I'm not in a position to direct the police. Those are beyond the purview of the Attorney-General and the Minister of Justice."
A number of Conservative MPs avoided comment on what has befallen the former ally of the Harper government. Mr. Ford endorsed Mr. Harper for prime minister and stood on a Greater Toronto Area stage during the last federal campaign to speak in support of the Conservative Leader.
On Tuesday, however, the Prime Minister's Office was coaching MPs to keep mum on the matter. Sources said that, if asked about the mayor, MPs were instructed to say: "I have nothing to add to your story. Let me know if you want to talk about job numbers."
Mr. MacKay said he was saddened by the news from Toronto.
"It's certainly a sad day for the city of Toronto, and I'm the Attorney-General of Canada, I'm the Justice Minister, you know where I stand on the use of illegal drugs. As a human being, I think that the mayor of Toronto needs to get help," the minister said.
Federal Industry Minister James Moore weighed in via Twitter, suggesting some Canadians are taking delight in Mr. Ford's misfortune and reproaching them for doing so. "Schadenfreude can be so incredibly ugly," Mr. Moore said via Twittter. "Particularly in the context of the disease of addiction."
Mr. Moore did not identify the mayor in his remarks. He did not comment on Mr. Ford when asked as he entered the House later that day.
NDP Leader Thomas Mulcair steered clear of the issue, saying Mr. Ford should do the "right thing," but did not say what that is.
"I sincerely hope Mr. Ford will do the right thing for Toronto and the right thing for himself, which includes taking care of himself properly," Mr. Mulcair said. Pressed again on what the mayor should do, he said: "I think Mr. Ford should do the right thing for Toronto."
Liberal Leader Justin Trudeau, whom Conservatives have taken to task over his admitted use of marijuana, declined to compare his situation with that of the Toronto mayor.
"I'm not going to politicize. I'm not going to look for a political advantage or defence in this. I have been honest and forthright in my own decisions, my political decisions. And I look forward to seeing Rob Ford get the help he obviously needs," Mr. Trudeau said.
Several Conservative MPs from the Toronto area declined comment, including Chris Alexander, Stella Ambler, Brad Butt and Eve Adams. So too did Finance Minister Jim Flaherty, a friend of the Ford family, who quietly mouthed "no comment" as he entered the House of Commons.
One Conservative MP, Stephen Woodworth of Kitchener, Ont., was asked about Mr. Ford in light of the party's comments about Mr. Trudeau's admitted marijuana use.
"I'm not familiar with what Rob Ford does. As a general principle, I believe people ought not to pollute their bodies. So if you ask me, should someone pollute their body, I would say no," he said, before being asked about the Conservative changes to drug penalties in the criminal code.
"Actually, you know, it's very important for politicians not to intervene in criminal prosecutions. And often politicians can be criticized if they attempt to direct the police. The police should be entirely above political interference."
Asked about Mr. Ford, B.C. Conservative MP John Weston said he had been in an unrelated meeting, "celebrating those who had been in recovery," not specifying from what.
"I think for me it's a strong message that Canadians have to be aware of drugs, and avoid them. But also, for those in recovery, to support them," he said, adding: "I'm not here to advise the mayor. I am here to say, in terms of health and fitness for the country, we as a nation need to get away from these problems and support those who are struggling to get out of their addictions."
Another MP said Mr. Ford's crack admission was disappointing.
"That's illegal, so it's up to the RCMP and Toronto on how they're going to handle that," said B.C. Conservative MP Mark Warawa, declining to say if he thinks the mayor should resign. "It' s not my place to say. I mean, it's an illegal act and it's disappointing that a mayor would be involved with illegal activities."
NDP MP Peggy Nash, who represents a Toronto riding, called it a sad day after Mr. Ford's admission.
"It leaves a lot of people concerned in the city of Toronto. I think it's a sad day for our city, that we're in this situationWe've got a great town, and I think people want to move the city forward. It's hard to be dealing with all these crises," Ms. Nash said. Asked if Mr. Ford should step down, she said: "I think the people of Toronto deserve and need a full-time mayor who is going to be on the job, every day, devoting his full attention to the needs and the future of the City of Toronto."Report Typo/Error
Follow us on Twitter: @stevenchase, @josh_wingrove


text:
The Grade 1 students at Yorkview School recently completed a science unit on "Materials, Objects, and Structures" with a half-day trip to the Dundas museum. Their teacher, Carrie Mullins, had spent a morning during her March Break exploring the newly renovated museum and discovered a new space that could possibly work for a school trip for her students. The renovated multipurpose Education Centre has a very pleasant and large heritage room where students could gather to further their learning in history, science, and social studies.

Excited about the possibilities, Mullins contacted the staff at the Dundas museum, including the museum's assistant, Esther Brouwer, and the recently appointed director of education, Dr. John Picone, to explore the possibilities of combining the science unit with a study of older materials and objects. Dr. Picone's mind started to, "spin with the possibilities," and, after a flurry of emails back and forth and many hours of preparation, Dr. Picone, alias "Professor Interrogo," was ready to welcome the Grade 1 class for a morning of discovery and learning.

What happened next was beyond Mullins ' expectations. As the Yorkview students rounded the last corner of their walking trip to the museum, Prof. Interrogo was waiting, in character, at the front door. Prof. Interrogo greeted the students, parents volunteers and teacher, and escorted everyone to the heritage room. With the aid of the latest modern presentation technology combined with Prof. Interrogo's masterful grasp of the Ontario Science Curriculum for Grade 1, the students participated in a couple of hours of review of classroom material and new material, combined with hands-on exploration.

Dr. Picone's 30-plus years of experience in education ensured a highly entertaining and stimulating experience for all. He varied the instructional strategies, just as a master teacher would do; using a combination of lecture time, discussion time, and questions and answers with movement to the older section of the museum for some hands-on examination of artifacts. Just when we thought the presentation was complete, we discovered that Prof. Interrogo had set up three tables filled with actual artifacts that we could handle with care. The students were instructed to sort and classify the objects. They also learned the purpose of several of the unfamiliar objects that are not found in today's homes. Throughout the visit, the students wore their "I Wonder" science glasses, given to them courtesy of the museum. The visit concluded with a craft, followed by enjoying their lunches, before starting the walk back to school.

Several weeks later, Tara Fink's Grade 1 and 2 class from Yorkview embarked on the same walk to the museum to participate in activities based on their social studies unit, Features of Communities. In the meantime, Dr. Picone had developed this presentation as well, which was stimulating and exciting for the children as they learned about the Dundas community, including the mill, as it once was. When the children returned to Yorkview, there was a definite buzz in the air, as they discussed their interesting school trip.

Both Fink and Mullins recommend that other schools in the community consider a trip to the Dundas museum for their students, now that the new multipurpose Education Centre is operational. It is free, educational, presented by an experienced professional who is willing to create presentations tailored to your needs, and in walking distance of most Dundas schools — a winning combination. Professor Interrogo may be reached at email@example.com.


text:
|Message view
|« Date » · « Thread »
|« Date » · « Thread »
|Greg Ames <grega...@remulak.net>
|dumps on Linux: some progress
|Thu, 09 Aug 2001 15:10:03 GMT
Last nite I figured out how to get a core dump of a threaded server on Linux when it seg faults. After Justin pointed out that he's seen dumps w/threaded, I noticed that I had a few old dumps in my home directory, and one in root's home directory, but nothing my configured CoreDumpDirectory (writeable by everybody w/the sticky bit set). I had "User nobody" and "Group nobody" in my config file, to match daedalus as closely as possible. hmmmm..."nobody" doesn't have a home directory. So I created "webuser" which does have a home directory, and only belongs to its own group. Changed the config file to use this user/group, fired up threaded with mod_cgid, did an "apachectl restart", and voila! a coredump appeared in my CoreDumpDirectory. I still don't know exactly what the deal is here (i.e., is it important that "webuser" has a home dir? is Mandrake's security stuff or Linux itself doing something to "nobody"? does this have anything to do with using threads?) but thought it might be useful to other folks. Still nothing in the error log. This shouldn't be a surprise - we don't have code that logs when the parent itself seg faults. Thanks to Justin for letting us know that core dumps are possible w/threaded on Linux, and to Ben whose Horse book is where I got the idea for "webuser". Greg
|View raw message


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text:
By Dan Vergano, USA TODAY
WASHINGTON President Obama on Monday called for a renewed national commitment to science and education, promising to back his vision with a bully pulpit and increased funding.
"Science is more essential for our prosperity, our security, our health, our environment, and our quality of life than it has ever been before," Obama said, speaking here at the National Academy of Sciences.
Obama said the nation should spend more than 3% of its total economic output, or gross domestic product, on research and development, an increase of about $50 billion that would make the financial commitment "exceed the level achieved at the height of the space race."
"The president recognizes that science, technology and innovation, as well as science education, are critical to our economic recovery and to the long-term future of this country and of the planet," says science budget expert Al Teich of the American Association for the Advancement of Science.
To applause from the audience of scientists, Obama also called for:
•A federal effort to inspire students to pursue science and engineering careers, particularly "clean energy" ones, through education and scholarships.
•The creation of an organization within the Energy Department, called the Advanced Research Projects Agency, devoted to developing "breakthrough energy technologies."
•A decade-long $42.6 billion budget-doubling for the National Science Foundation, National Institutes of Standards and Technology and Energy Department's science office.
The nation now spends about 2.6% of its $14.2 trillion GDP on research and development, primarily in the defense industry, according to the National Science Foundation. Most of that development funding comes from industry, more than $270 billion, with federal agencies spending roughly $100 billion. Recent stimulus spending added $21.5 billion to the federal total this year.
"As a scientist, I am delighted with the strong pro-science positions of the Obama administration, and hope they survive the difficult and inevitable aftermath of stimulus spending," says former Bush administration science adviser John Marburger, by e-mail, expressing concern that some of the proposed funds will be spent unwisely.
"The devil is in the details," Marburger adds, warning that Congress may try to direct research funds to special interests. Increased science training, as well, "needs lots of practical analysis of workforce supply and demand so young people are not recruited into fields that can't feed them."
Guidelines: You share in the USA TODAY community, so please keep your comments smart and civil. Don't attack other readers personally, and keep your language decent. Use the "Report Abuse" button to make a difference. Read more.


text:
Columbia, S.C. • In his first public speech since resigning as U.S. ambassador to China, Jon Huntsman Jr., a Republican considering a presidential run, steered clear of politics, left out the fireworks and focused instead on salient advice to graduates of the University of South Carolina.
The former Utah governor did, however, offer what might be his best argument for why he served as an ambassador for the Obama administration, which may be a concern for Republican voters in this key primary state.
"Give back as much as you're able," Huntsman told the hundreds of graduates on Saturday in Columbia. "Work to keep America great. Serve her, if asked. I was, by a president of a different political party. But in the end, while we might not all be of one party, we are all part of one nation, a nation that needs your generational gift of energy and confidence."
Less than a week after resigning his diplomatic post and returning to the United States to consider his own presidential aspirations, Huntsman struck a patriotic and optimistic tone in his commencement address, one of two he's giving this month. In two weeks, Huntsman is slated to give the address at Southern New Hampshire University.
More than a dozen reporters lined press row to hear Huntsman, a much larger gaggle of scribes than Supreme Court Associate Justice Sonia Sotomayor drew the night before for her commencement speech.
Huntsman, dressed in the university's garnet robe, didn't use the opportunity to set up any presidential buzz, although he did toss out a few lines about the country's optimistic future that, should he run, are likely to show up in campaign stump speeches.
"Our free and open society that can respectfully embrace debate, coupled with a free market system that rewards risk and innovation, is still the envy of the world," Huntsman said. "We are still as full of potential as ever."
Some in China might think America's best days are over, Huntsman said, while there are those in America who fear their country has lost its leading role on the international stage.
"But these people aren't seeing things from my earlier vantage point of 10,000 miles away," Huntsman said. "The way I saw it from overseas, America's passion remains as strong today as ever."
Seeking to reach young graduates, Huntsman sprinkled his speech with a few "cool" and "awesome" references, read lyrics from rockers Ben Folds Five and acknowledged to the crowd that he dropped out of high school to join a tribute band called Wizard.
"Wizard didn't make it, but I'll never regret following my passion," Huntsman said, suggesting graduates stop asking others what they should do with their lives and follow their own paths.
"Be you, remember others, embrace failure, find someone to love, give back, [and] never forget to rock 'n roll," Huntsman said, summing up his speech.
The speech appeared well-received at graduation ceremonies, but mentions of him at the state Republican convention a block away were almost nonexistent. Several candidates exploring a presidential bid spoke to the crowd, a group that's proud of its spot as an early gauge of presidential contenders.
Huntsman didn't set foot in the GOP dinner or convention, and that omission showed when Republicans there cast their ballots for their favorite presidential candidates.
Out of 408 cast, Huntsman collected a mere four votes.


text:
|Home > National News > Article
The day after this photograph was taken, Tamandani died. She was one year old. She had been brought into the Queen Elizabeth Hospital in Blantyre, Malawi, by her mother, who was also suffering from malnutrition, causing her milk to fail.
At the hospital's Nutritional Rehabilitation Centre, a MUAC (measurement of upper arm circumference) tape was used to show her level of malnutrition. Green is normal, yellow shows a degree of malnutrition, red indicates starvation. Tamandani's arm measurement was right in the middle of the red.
All the family had had to eat for many days was pounded cassava or pumpkin leaves, her mother said.
There is a simple cure for malnutrition: more food. But in Malawi, as in large parts of southern Africa, the staple crop of maize has failed for the second season in a row, due to drought. The United Nations World Food Program estimates that 3.2 million people in Malawi, and 14 million people in southern Africa, face death by starvation unless there is a massive international response.
In villages across Malawi tiny graves are being prepared and families are mourning children, who are the first to die in any famine. On rural dirt roads a frequent sight is the chopped-off branches of trees with green leaves, a sign that a funeral is going on nearby. Traditionally, neighbours bring food to the funeral wake, but this year there is no food to bring.
Malawi is one of the most densely populated countries in Africa, with between 10 million and 11 million people. About 80 per cent are subsistence farmers.
With no social safety net, crop failure quickly translates into food shortages.
Yet there is still time to prevent a catastrophic "Ethiopian-style" famine in the region, aid agencies say. Millions of people will need assistance to help them survive until March or April, when the next main harvest can be expected.
The Age southern Africa famine appeal has passed $600,000.
Caritas Australia 1800 024 413; World Vision Australia 13 32 40; and Oxfam Community Aid Abroad 1800 034 034.
Donations can be made online at www.worldvision.org.au: www.caritas.org.au; www.caa.org.au
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Name behind petition has signatories running
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Gambling tycoon Sheldon Adelson wants to outlaw online gambling, which threatens his casino industry. So with the help of Sen. Lindsey Graham (R, SC), he has formed an alliance with Southern Baptists, who also oppose online gambling because they oppose gambling in general, including what goes on in Mr. Adelson's casinos. So we have a gambling magnate using gambling opponents to help him eliminate competition.
But this paradox is not new. There was also an alliance between bootleggers and (again) Baptists in promoting Prohibition. In fact, the phenomenon has a name in the field of economics: The Bootlegger/Baptist theory of regulation. [Read more…]


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Hahnville boy earns Cub Scouts religion badge
From staff and wire reports - Jun 28, 2012
Christopher Thibodeaux, of Hahnville and Cub Scout Pack 370, has successfully earned the Light of Christ Emblem.
The award was presented on May 5 at St. Matthew the Apostle Catholic Church by the Most Reverend Shelton J. Falore, Auxillary Bishop of New Orleans. Christopher is the son of proud parent Jenny Thibodeaux.
Read More Stories at HeraldGuide.com!
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Comfort Shawl aka "Auntie Em" Shawl by Mary Triplett
Welcome! You are browsing as a guestWould you like to see 6 projects made from this pattern and much more? create a free account What am I missing?
Comfort Shawl aka "Auntie Em" Shawl
This pattern is available for $6.00 USD buy it now
I design this shawl when I started thinking about what I thought "Auntie Em" of the Wizard of Oz would wear. I decided to use chunky yarn thinking how comfortable it would look and feel on my shoulders. However, after using the chunky yarn, I then preceded to work up the shawl in dk weight yarn and in lace weight yarn. The stitch pattern is such that you can easily keep going for as long as you want. A different weight yarn a different look. The collar is also optional.


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I would like to hire a Social Media Marketer
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Rent The Force of Domesticity 1st edition today, or search our site for other textbooks by Rhacel Salazar Parrenas. Every textbook comes with a 21-day "Any Reason" guarantee. Published by New York University Press.
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Katahdin Drive-In
Route 157,
Route 157,Mattawamkeag, ME 04459
No one has favorited this theater yet
The Katahdin Drive-In closed in the 1980's. Car capacity was 300.
Contributed by Lost Memory
Recent comments (view all 1 comments)
Mike Rogers on November 23, 2010 at 8:33 pm
I have C.E.Monscone and L.Bilolean owning this drive-in.Also "AIRPORT" played here with "MILLION DOLLAR DUCK" next feature.Didn't seem to run a lot of Double features.
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Just login to your account and subscribe to this theater
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Nanaimo Transportation Master Plan
On this page you can find information about the following topics:
- The Plan
- What's New - Nanaimo Transportation Master Plan approved by Council
- Getting Ready, Discussion Paper One, Two and Three
- How Can You Get Involved
- Keeping Up to Date
The Plan
The City of Nanaimo completed developing its first long-term multi-modal Transportation Master Plan. The first plan of its kind for BC's third oldest city. Transportation touches every part of our daily lives, affecting how we move, how food, goods and services reach us, how we access employment, our household budgets, what housing choices we make, how our City looks and feels and how we interact with our fellow citizens.
As our City approaches 100,000 people, transportation issues will become more complex requiring a coordinated strategy moving into the future. The Nanaimo Transportation Master Plan will guide transportation decision-making over the next 25 years and will recommend improvements for all modes of transportation, including walking, cycling, public transit, goods movement, and vehicles. The Plan will ensure that transportation investments work towards achieving the City's strategic goals, make the best use of our tax dollars and help shift towards a more sustainable future.
The Plan seeks to address key objectives of the City's Official Community Plan, Strategic Plan, and the Regional Growth Strategy and will help create a future transportation system with attractive alternatives to the car and support a shift towards more sustainable transportation options. Principles identified through consultation created a vision for a future transportation system that provides mobility across all transportation modes that is safe, connected, sustainable, affordable and accessible for residents of all ages and abilities. The Plan includes targets to both increase the use of sustainable transportation modes and to reduce the growth of vehicle use. By 2041 the Plan seeks to shift the City's travel patterns by;
- doubling the proportion of trips made by sustainable transportation modes, from 12 to 24%,
- increasing the number of walking trips (2x), cycling trips (5x) and transit trips (5x) over current conditions, and
- reduce vehicle travel from just under 14 km to 10 km/day/resident.
The Plan provides the long-term directions that will guide transportation policies, priorities and investments within each element of the transportation network, including:
- Better coordinating land use and transportation planning to create future developments and neighbourhoods that are more walkable, rideable and can be effectively serviced by transit.
- Making walking and cycling a more comfortable way to move throughout more parts of the City for people of all ages and abilities.
- Increasing the quality, convenience and accessibility of transit for trips within the City and region.
- Major roads improvements that make best use of the existing infrastructure create streets that are comfortable for all road users and create an effective future road network, while seeking to reduce our use of cars.
- Parking management strategies that support the development of quality urban environments in key areas of the City and reflect the expectation that less, but better utilized, parking will be needed in denser, mixed-use areas as walking, cycling and transit become more attractive.
- A refreshed approach toward Neighbourhood transportation to manage the impacts of traffic while encouraging walking and cycling within neighbourhoods; enhancing their livability and sustainability.
- Improving strategic connections for people, goods and services that support our economy between Nanaimo and adjacent communities on Vancouver Island as well as to Metro Vancouver and the rest of British Columbia.
What's New - Nanaimo Transportation Master Plan approved by Council
On May 26th, 2014 council meeting, the Nanaimo Transportation Master Plan was approved unanimously. The approved Plan document includes an improved layout and incorporates additional input from stakeholders and final recommendations from the Transportation Advisory Committee.
The Plan is composed of four major sections, including:
- Sections I and II provide community context and the overall direction.
- Section III includes stand-alone chapters providing detailed policies and actions for each element of the transportation system.
- Section IV provides a summary of short-term priority projects over the next five years.
To download the Nanaimo Transportation Master Plan approved document, click here for Low resolution [PDF - 9 MB], click here for high resolution [PDF - 160.1 MB]
Getting Ready, Discussion Paper One, Two and Three
In order to get ready for the NTMP, the city conducted a pre-plan consultation to gain insight into community expectations and areas of interest. Results from the pre-plan consultation can be found here. In addition, in Spring 2012 the City's Strategic Plan identified transportation as a key priority for the community. The City has also been assembling information on our current travel patterns through a series of traffic, travel and transit surveys during 2012. Click here for more information on this work.
Phase One of the NTMP took place during Fall 2012 and Winter 2013. It included multi formats public consultation and preparation of a Existing Condition Report. This Discussion Paper begins with a review of policy initiatives at the local, regional, and provincial levels that influence the transportation system and provide guidance for the City as it develops the Transportation Master Plan. The following sections of the paper provide a comprehensive assessment of Nanaimo's pedestrian, bicycle, transit, and road networks, identifying challenges and opportunities to be addressed through the development of the NTMP.
The public input, information and data collected in Phase One, the OCP and Strategic Plan were used to develop a plan vision with goals and objectives. The NTMP's vision, supported by guiding principles, mode and topic-specific goals and objectives are the outcome of Phase Two. Phase Two recommends mode share targets to measure progress towards achieving the stated goals and objectives. Discussion Paper #2 Setting Future Directions (August 2013) presented the outcome of Phase Two.
Developed in the fall of 2013, Discussion Paper #3 - Transportation Possibilities outlines potential policies and actions for each element of the NTMP including: land use, walking, cycling, transit, major roads, neighbourhood transportation, parking and strategic connections. These policies and actions have been developed to meet the targets, goals and objectives of the NTMP (Discussion Paper #2) and address the issues and opportunities identified through consultation in the Fall of 2012 (Discussion Paper #1). The Transportation Master Plan was developed based on the feedback received during the consultation phase.
How Can You Get Involved?
The Nanaimo Transportation Master Plan process is nearing completion. If you have any additional comments please send an email to:email@example.com
Keeping Up to Date
This site is the main portal for information about the NTMP. We invite you to visit it for updates as the Plan moves forward.
Go to Top


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Summer 2008
Your Money Matters Home
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New Kapahulu Branch
Kapahulu Branch: (left to right) Kathy Ishiro, Galileo Tan, Sophia Ahuna, Susan Dolloff, Gareth Shimizu, Kelsey Brown, Jade Amaral, Vey Okutsu and Robert Hammonds.
Central Pacific Bank's Kapahulu Branch has a new and improved location! The new branch is located at 830 Kapahulu Avenue, near the new Safeway in the Avenue Shops at Safeway Complex.
|The articles and opinions in this publication are for general information only and are not intended to provide specific advice or recommendations for any individual. Although it is intended to be accurate, neither the publisher nor any other party assumes liability for loss or damage due to reliance on this material. All credit products mentioned in this publication are subject to credit approval and certain restrictions apply. Your Money Matters is published by Central Pacific Bank Marketing Division. Images may be from one or more of these sources: ©Jupiterimages, ©Getty Images, ©iStock, ©PhotoSpin. © 2008 Central Pacific Bank


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Are you a member of the media? Visit our media kit to download a trend summary and more information about requesting an interview with Rohit >> This week I launched the seventh edition of my annual trend report featuring all of my research from throughout the year on trends. Many of you have already pickedContinue reading »
Category Archives: "Small Business Friday"
In case you hadn't noticed, your bank wants to upsell you more services – and sometimes that's not a bad thing. Unless your bank happens to be HSBC. There is a well known model in the financial industry for customer evolution that is based on lifetime customer value. If you deliver a great service andContinue reading »
There's a few things they don't tell you about being on The Shark Tank. One of them is that every pitch on the popular reality business TV show starts with a silent 10 second staring contest. I spent an afternoon talking to a former (winning) contestant from the show, and one of the the insightsContinue reading »
In just a few weeks, it will be time once again for one of my favourite marketing events of the year. No, it's not the party-filled serendipity fest of SXSW, or the Las Vegas geek-pride gathering at CES. The event I'm talking about is all business … and that's why it's one of my topContinue reading »
Looking back, it's fair to say the launch strategy Google used back in 2004 has become legendary. When the new platform first came out offering an unheard of 1 GB of free storage space, it was only available to an extremely limited group of people. As a result, having a Gmail account became an earlyContinue reading »
There is a very good reason that milk has an expiration date. No one wants to have crusty lumpy milk in their fridge. A lot of food in general is required by law to have these expiration dates. It is the most familiar of all deadlines that all of us experience in some way almostContinue reading »
The books on your shelf say something about you. That's why most of us have books that we put on our shelves over the past year which we haven't quite had a chance to read yet – but still display as a declaration of what we believe. As an author, I usually make it fullyContinue reading »
What's the Trend? New services and technology makes it easier for anyone to invest in local businesses and buy from local merchants. The consumer desire to "shop local" will have plenty of help in the coming year from a suite of online tools, innovations and personalization technology that help anyone in any location around theContinue reading »
What's the Trend? New and old friends change the travel experience by curating where to go, and offering more local authentic experiences. Your friends are the new travel agent and tour guides, as a host of new services online and offline enable any traveler to get recommendations for unique experiences from friends. Beyond recommendations, thisContinue reading »
There has been a single pink folder on my desk since January 15th of this year. That day matters to me for two reasons – first because its my birthday, and second because it's the day when I start an empty folder with the intention of collecting ideas for my year end trend report. ThenContinue reading »


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Have a Tax Question? Ask a Tax Expert
It's hard to see why they say that, unless there was some mistake in your return .
From their site:
An addition to tax is imposed for failure to file or failure to pay. An addition to tax is imposed for failure to fileby the due date at the rate of 5 percent per month, not to exceed 25 percent of the unpaid balance.
so that should be ... not to exceed $25 in you case
What may be happening here, is that they are not taking withholding into account at all
Also, just fund this:
Residents who receive a notice of adjustment or notice of deficiency must file their official protest of deficiency disputing their tax liabilities within 60 days.
Taxpayers can file appeals with the Administrative HearingCommission, an independent state government agency, to appeal the Department of Revenue's Final Determination ruling within 30 days of when the Department of Revenue mails its decision.
Here's an excellent overview: http://www.justanswer.com/tax/7uufs-live-state-missouri-file-taxes-every.html
Sorry that was the URL for THIS site ... Here we go: http://www.ehow.com/info_7976389_missouris-statute-limitations-tax-debt.html
Did you have taxes withheld from your pay?
If your amount of 100 is even close then there's really something wrong with that $3000 number
I would speak with either a CPA or a tax attorney, but if there were funds withheld, you should be able to file at anytime to show that the amount you owe is not the entire amount... if that is what is making the number spo big
especially if you are within a year or so
Here's an attorney in MO that specializes in tax issues: http://www.carnahanlaw.com/IRS/motaxcollection.html
My advice wold be to file your return with them as soon as possible ... WHen you don't file they will calculate the number with whatever information they have
By filing your tax return - you are informing the department of revenue about your actual tax liability. They will review your tax return and if accepted,this assessment will be relieved.
Most of thme when they do this, they don't even use all of the deductions and credits that may be coming to you ... it
's essentially a scare tactic
By filing, you take all of that off the table and THEN you may owe a little interest
I still don't see you coming into the chat, so I'll move us to the Q&A mode ... we can still continue a dialogue there, just not in real-time chat as we can here
Let me know if you have further questions, but if you received a letter like this ... http://www.sedm.org/SampleLetters/States/Missouri/MO-ReqToFile2-20060924.pdf ... you need to simply send in your taxes, so that the amount owed can be adjusted.
hope this helps
Hi Jennifer,
... just checking back in, as I never saw you come into the chat.
Again, they are probably simply calculating the tax without applying any of the deductions, credits or withholding that may apply.
Sending in your return (I would send it by certified mail/return receipt, so you have proof that it was received) is what will give them enough information to adjust the tax owed to right number.
We mailed in our return when my husband sent the letter. We did have taxes withheld from our income that year. I don't remember a letter like that, but the letter we received today said we had ten days to pay. There is just no way I see that it is right for them to demand $3000+ from me when we only owed a little over $100. We had a refund this year of almost $160 which they took to put towards our last years return. It looks like we will have to contact some expert as we are not going to be "scared" into paying something we do not owe.


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So....I had this idea to make this video thanking you guys and stuff....but it turned out SO BAD. So watch at your own risk, and you'll probably make fun of me for the rest of my life after you see the bloopers and....bonus content at the end.
Here's to a better New Year?
I don't even like Nicki Minaj.
Anyways...Happy New Year, guys!


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Ok , so I'm doing it again – not the game playing, but the using one thing to procrastinate from doing the thing you should really be doing.
And what I'm doing is reading blogs, on twitter, Facebook, linkedin, and fine-tuning my own blog, all as a way of not actually "DOING IT". I'm working at getting the blog ready, but how ready does it need to be? I think it's time to either do it or let it go. And, I know that I don't want to do that. So …
I need to:
Stop Wasting Time. I know that this learning period is good, but it's amazing how much time can go by just doing those things listed above. On twitter you click on one post, which leads you to another and another and another – before you know it you've got a dozen windows open and have no idea how or why you got to number twelve. In my short time on the blogosphere I can see how useful social media is, but I have to budget the amount of time I spend on there.
Start posting to the blog regularly. I need to realize that each post isn't going to be perfect, it isn't going to interest everyone who drops by, but it has to be put out there. I know that part of this procrastination is due to how nervous I feel about 'putting myself out there', and I know that it just isn't rational, because, in truth, not too many people will be reading these early posts, so what's the big deal? That's the big question!
Set up a Schedule. I need to decided how many times a week I want to post, and work backwards from there. Then, set aside the time needed to research, write, and revise 'X' numbers of posts per week.
Commit to that Schedule. Tell my readers that I will be posting on certain days and then DO IT.
For now, my mantra is "Just Do It".
What do you do to when you know there's something you should be doing, but it scares you to death?


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The amount of pocket money children in Britain get has fallen for the third year in a row, a survey has found.
Children aged between eight and 15 get £6.13 pocket money a week on average.
But last year the average was £8.01, and in 2005, it was even higher, at £8.37!
Researchers say parents are giving kids less cash, but are paying for more expensive things like mobile phones and MP3 players.
Tony Wilcox, from Halifax bank, said: "Our latest findings really show a mixed bag - pocket money doesn't appear to have increased this year, but children don't seem to fund any major expenses from their allowance."
Researchers questioned 1,180 children aged between eight and 15, from across Britain.


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STREAMING: Necrowretch "Putrid Death Sorcery"/
Back in the old days---1988-1991---you didn't need to sound "retro" to be cool. Even if you sucked you were cool because you were death metal. Black and white band photo, a group of scowling dudes, the obligatory cemetery backdrop (or rubble heap), and a kick-ass logo were all you needed to convince worldwide throngs you belonged with the rest of the pack. In the new days---i.e., now---the essentials don't mean shit. You're cool because somebody on an Internet forum says you're cool. A tastemaker with an audience of 12. Actually, that's not true. Take France's Necrowretch, for example. For years---since 2008, actually---they've toiled in obscurity, releasing demos and 7"'s on labels small and cult. Well, it didn't take long before death metal's original Eye of Sauron (aka Century Media Records) gazed upon the Rhône-Alpes region of France and found, like they had back in the old days, something real, something cool, something decidedly violent and altogether evilly incandescent. Sure, Necrowretch owe their very existence to bands before them, but not the bands normally cited in I-love-the-past treatises. Right. No Entombed or Nihilist. Carnage or Dismember. We're talking Merciless. With a smattering of Blasphemy.
It's time to put on your black pants, your never-washed jean jacket, and a pair on non-descript black shoes---Adidas makes an all-black Samba just so you know. It's time to wage war on hump day. It's time for Necrowretch to rise from their moldy grave to rule all!
** Necrowretch's debut full-length, Putrid Death Sorcery, is out February 5th on Century Media Records. Pre-order it HERE to get a good vile dose of the bubonic plague. Go on now. It's what all grown-up metal of deathers do these days.


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CICS Social Media Aggregator
John Knutson Tags: social_media cics blog 3,540 Views
This post is an iframe for the CICS Social Media Aggregator. The page is dynamic will update as new content arrives. The links and buttons are active so you can participate. For a full page experience, visit https://www-304.ibm.com/social/aggregat...
from Blog: CICSdev CommunityModified on by John Knutson
Privacidade em tempos de Big Data
ctaurion Tags: privacidade social_media dados big_data 8,793 Views
Recentemente vivenciei uma experiência interessante. Em um evento sobre Big Data surgiu o inevitável questionamento sobre privacidade. Perguntei aos presentes se os desafios de privacidade em tempos de social media e Big Data era...
Stay out of the poisoned watering hole (and other social attacks) Community Blog
Kane Scarlett Tags: security-intelligence poisoned_watering_holes social_media security threats michael_hamelin 2013_mid-year_trend_and_r... x-force 2,377 Views
Michael Hamelin is back with more from the IBM X-Force 2013 Mid-Year Trend and Risk Report [ Read about it | Get the report ]. In this interview, he discusses social media attacks -- reputation stealing, duplicate passwords, and poisoned watering holes. 8:33...
from Blog: Security on developerWorksModified on by CalvinPowers
Our Ever-Expanding Social Presence
KelleyAnders Tags: blogs social_media cics facebook dw websphere linkedin youtube feedback developerworks twitter social ibm-education-assistant 7,847 Views
... which is much more desirable than an ever-expanding waistline! Back in October, Maryam Ahmed reminded our viewers " We Still Love Your Feedback ". In December, Luc Leblanc shared our current social media channel implementation with his...
Eye on IBM | 011613 | Profiting from social, predictive, and risk analytics
Kane Scarlett Tags: roundup eye_on_ibm isam developerworks security risk_analysis social_media analytics 3,570 Views
VIDEO Installing and configuring the IBM Security Access Manager | 9:06 Steve Herskowitz demonstrates how to install the IBM Security Access Manager virtual machine image into VMWare. Watch more videos on ISAM . VIDEO Is social media a key to gain meaning...
TWOdW: Some of the best gifts come in the form of knowledge
Kane Scarlett Tags: backlog_grooming rest application_development developerworks andy_glover rational_team_concert twodw slim_framework tivoli_directory_integrat... system_notifications java social_media 7,603 Views
This week on developerWorks, we're handing out gift ideas, including a make-your-own developerWorks poster, Grady Booch's slogan tshirt (Front: "What if developers ruled the world"? | Back: "They do.") , and ... the real presents ... knowledge from dW: ...
How Social are We?
Bill Wentworth Tags: blog cics websphere facebook twitter social_media 4,132 Views
WebSphere and CICS Support, including the IBM Business Process Management products, have a significant Social Media presence. During the last couple of years, we've grown our presence in the Social Media space to better serve you. You can see us on Twitter,...
How Social are We?
LucLeblanc Tags: twitter websphere facebook blog cics social_media 7,750 Views
How Social are We? Today, our IBM Software Support Portal offers just a piece of our complete support offerings. During the last couple of years, we've grown our presence in the Social Media space to better serve you. Why are we out there? Because we want to...
Engage the IT community with these three options
Kane Scarlett Tags: knowledge_distribution community ibm_champions developerworks collaboration social_media knowledgebase 3,939 Views
You know, there are a lot more questions than answers on the web and surely you are an expert in something that someone wants an answer to. Learn how you can put your IT expertise out for developers to use. There are just three key concepts to remember --...
IOD 2012: Ken Bisconti on wrangling growing data volume
Kane Scarlett Tags: iod2012 iod-2012 conference defensible_disposal social_media enterprise_content_manage... think_big iod_2012 developerworks ecm big_data information_management content_navigator ken_bisconti business_analytics 2,751 Views
VP ECM Ken Bisconti outlines the state of enterprise content management at IBM and explains volume (80 percent of which is unstructured), variety (also weighted towards the unstructured), velocity , and veracity . And now a fifth V, value ... what should we...


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Modern lighting innovation plays with effortlessly chic forms to create the Chromaglo™ LED round reflector ceiling light by Sonneman. A suspended compact LED disk beams targeted direct light downward, and ambiently reflected light upward, assisted by the overhanging round white acrylic shade. Satin nickel finish on the base and suspension completes the icy sophistication. The Chromaglo's clean lines and contemporary style will truly set a tone in the dining room or living room.
One of the most acclaimed designers in the lighting industry, Robert Sonneman has received scores of international accolades for sleek, contemporary designs. From bath bars to sconces and wall lights, Robert Sonneman's passion for quality and cutting-edge style shines through in each and every design. If your home deserves the best European inspired lighting creations, it deserves Sonneman.
Our team has over 100 years combined experience with contemporary lighting.
Every EuroStyleLighting.com order is backed by our 100% Satisfaction Pledge.
Shipping and Delivery Information - For item EU1D703 if ordered by 1 pm Pacific Time


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Flax Fox's Profile
Flax Fox is a small local independent business created by Danielle Morgan & Bridget Farmer in 2010.
We saw a gap in the market for simple yet stylish souvenir products that could rival any other souvenir product across the globe. Ambitious? Yes! But this is an exciting time for Northern Ireland. We want to show off our beautiful landmarks to the rest of the world...just watch this space!!Flax Fox's loose illustrative style is our trade mark....
All images are drawn initially from life and then a range of products are created from these sketches. Original Screen Prints are printed in the Belfast Print Work shop, followed by a range of commerial artist tea towels, A5 Postcards and fine Art Giclee Prints designed and sold locally in Belfast.
- Female
- Born on April 23
- Joined September 30, 2010
Favorite materials
- Flax Fox
- Belfast, Northern Ireland, Ireland, Uk