text:
Forum Registration
Registration for the inaugural Library Publishing Forum is now open.
We are pleased to announce the inaugural Library Publishing Forum. This event will bring together representatives from libraries engaged in (or considering) publishing initiatives to define and address major questions and challenges; to identify and document collaborative opportunities; to strengthen and promote this community of practice; and to advance this vibrant subfield of academic publishing. We encourage library publishers (and friends of library publishing) of all sizes and statures to attend, including both administrators and technical staff charged with this important scholarly communications function. The Library Publishing Forum will include representatives from a broad, international spectrum of academic library backgrounds, as well as groups that collaborate with libraries to publish scholarly works. You do not need to be a member of the LPC to attend this event.
Registration: $225 US (deadline February 28)
Registration includes breakfast, lunch, and refreshments on both days, as well as the reception on March 5. Please contact firstname.lastname@example.com with questions.
LP Forum 2014
Call for Posters
The Library Publishing Forum thanks our generous sponsors:
Silver Sponsors
Bronze Sponsors

subset: commoncrawl


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Get an overview of this hotelHotel in Durham with free breakfast and indoor pool
Popular property highlights
Situated in the business district, this hotel is 0.2 mi (0.3 km) from Northgate Mall and 2.4 mi (3.9 km) from Duke University. Vietnam Veterans Living Memorial and Brightleaf Square are also within 2 mi (3 km).
Hotel Features
An indoor pool, a 24-hour fitness center, and coffee/tea in a common area are available at this smoke-free hotel. Free buffet breakfast, free WiFi in public areas, and free self parking are also provided. Additionally, a business center, a meeting room, and dry cleaning are onsite.
Room Amenities
All 137 rooms offer conveniences like refrigerators and microwaves, along with free WiFi, free wired Internet, and flat-screen TVs. Premium bedding, coffee makers, and free newspapers are among the other amenities available to guests.Information missing or incorrect? Tell us!Opens in a new window
Hampton Inn & Suites Durham North I-85
Hotel Amenities
Hotel Amenities
Hampton Inn & Suites Durham North I-85 features an indoor pool and a 24-hour fitness center. Public areas are equipped with complimentary wired and wireless Internet access. This hotel offers access to a business center and a meeting room. A complimentary breakfast is offered each morning. This business-friendly hotel also offers multilingual staff, coffee/tea in a common area, and complimentary newspapers in the lobby. Complimentary self parking is available on site.
Hampton Inn & Suites Durham North I-85 is a smoke-free property.
- Total number of rooms - 137
- Number of floors - 6
- Business center
- Coffee/tea in common areas
- Free newspapers in lobby
- Free breakfast
- Dry cleaning/laundry service
- Elevator/lift
- Express check-in
- 24-hour fitness facilities
- Designated smoking areas
- Free WiFi
- Free wired Internet
- One meeting room
- Multilingual staff
- Luggage storage
- Safe-deposit box at front desk
- Free self parking
- Year Built 2012
- Smoke-free property
- Number of buildings/towers - 1
- Indoor pool
- Television in common areas
Family Friendly Amenities
- Family Hotel
- Indoor pool
- Free Wi-Fi
- Refrigerator
- Microwave
Available in all rooms: Free WiFi , Free wired Internet
Available in some public areas: Free WiFi , Free wired Internet
Free self parking
Room Amenities
- Premium TV channels
- Premium bedding
- Free newspaper
- In-room climate control (air conditioning)
- Air conditioning
- Phone
- Refrigerator
- Coffee/tea maker
- Microwave
- Daily housekeeping
- Private bathroom
- Designer toiletries
- Free toiletries
- Hair dryer
- Iron/ironing board
- Desk
- Blackout drapes/curtains
- Flat-panel TV
- Free WiFi
- Free wired Internet
- Connecting/adjoining rooms available
Where to Eat
Guests are offered a complimentary hot/cold buffet breakfast each morning.
Nearby Things to Do
Recreational amenities at the hotel include an indoor pool and a 24-hour fitness center.
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
- Accessible bathroom
- In-room accessibility
- Roll-in shower
Hotel Policies
Check-in time starts at 3 PM
Minimum check-in age is 21
Check-in time ends at 3 AM
Check-out time is noon
Payment types
Children and extra beds
- Children are welcome.
- Rollaway/extra beds are not available.
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on property policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
No rollaway/extra beds available
Hotel Name
- Hampton Inn Durham North I-85
- Hampton Inn I-85
- Hampton Inn I-85 Hotel
- Hampton Inn I-85 Hotel Durham North
We should mention
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.


text:
The impacts to our public transit system from the weather are starting to wind down — how was everyone's commute this morning? Here's what to keep an eye on this week in our area, particularly if you plan on riding the subway late at night:
D trains make local stops at 23 St and 14 St in both directions
Late nights, 12:01am to 5am, Tue to Fri, Jan 7-10
Allow additional travel time.
No G trains between Bedford-Nostrand Avs and Church Av
Late nights, 10pm to 5am, Wed to Fri, Jan 8-10
G service operates between Court Sq and Bedford-Nostrand Avs. Free shuttle buses make all stops between Bedford-Nostrand Avs and Hoyt-Schermerhorn, connecting with the F at Jay St-MetroTech. F trains make all G stops between Bergen St and Church Av. Transfer between shuttle buses, F, and A trains at Jay St-MetroTech.
N trains run via the Q in both directions between Canal St and DeKalb Av
Late nights, all times until October 2014
R shuttle service operates between 95 and 36 Sts, Brooklyn.
No R trains between Lower Manhattan and Downtown Brooklyn
All times until October 2014
R service operates in two sections: Between 71 Av, Queens and Whitehall St, Manhattan; and between 95 St, Bay Ridge and Court St, downtown Brooklyn.
These schedules sometimes change, so check mta.info for the latest information.


text:
by Staff Writers
Montreal, Canada (SPX) Nov 13, 2012
To build the computer chips of the future, designers will need to understand how an electrical charge behaves when it is confined to metal wires only a few atom-widths in diameter. Now, a team of physicists at McGill University, in collaboration with researchers at General Motors R and D, have shown that electrical current may be drastically reduced when wires from two dissimilar metals meet.
The surprisingly sharp reduction in current reveals a significant challenge that could shape material choices and device design in the emerging field of nanoelectronics.
The size of features in electronic circuits is shrinking every year, thanks to the aggressive miniaturization prescribed by Moore's Law, which postulated that the density of transistors on integrated circuits would double every 18 months or so.
This steady progress makes it possible to carry around computers in our pockets, but poses serious challenges. As feature sizes dwindle to the level of atoms, the resistance to current no longer increases at a consistent rate as devices shrink; instead the resistance "jumps around," displaying the counterintuitive effects of quantum mechanics, says McGill Physics professor Peter Grutter.
"You could use the analogy of a water hose," Grutter explains. "If you keep the water pressure constant, less water comes out as you reduce the diameter of the hose. But if you were to shrink the hose to the size of a straw just two or three atoms in diameter, the outflow would no longer decline at a rate proportional to the hose cross-sectional area; it would vary in a quantized ('jumpy') way."
This "quantum weirdness" is exactly what the McGill and General Motors researchers observed, as described in a new paper appearing in Proceedings of the National Academy of Sciences. The researchers investigated an ultra-small contact between gold and tungsten, two metals currently used in combination in computer chips to connect different functional components of a device.
On the experimental side of the research, Prof. Grutter's lab used advanced microscopy techniques to image a tungsten probe and gold surface with atomic precision, and to bring them together mechanically in a precisely-controlled manner.
The electrical current through the resulting contact was much lower than expected. Mechanical modeling of the atomic structure of this contact was done in collaboration with Yue Qi, a research scientist with the General Motors R and D Center in Warren, MI.
State-of-the-art electrical modeling by Jesse Maassen in professor Hong Guo's McGill Physics research group confirmed this result, showing that dissimilarities in electronic structure between the two metals leads to a fourfold decrease in current flow, even for a perfect interface.
The researchers additionally found that crystal defects - displacements of the normally perfect arrangement of atoms - generated by bringing the two materials into mechanical contact was a further reason for the observed reduction of the current.
"The size of that drop is far greater than most experts would expect - on the order of 10 times greater," notes Prof. Grutter.
The results point to a need for future research into ways to surmount this challenge, possibly through choice of materials or other processing techniques. "The first step toward finding a solution is being aware of the problem," Grutter notes. "This is the first time that it has been demonstrated that this is a major problem" for nanoelectronic systems."
Related Links
McGill University
Computer Chip Architecture, Technology and Manufacture
Nano Technology News From SpaceMart.com
|The content herein, unless otherwise known to be public domain, are Copyright 1995-2014 - Space Media Network. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA Portal Reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. Advertising does not imply endorsement,agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. Privacy Statement


text:
May 7, 2002
AMHERST, MA - The Amherst College women's golf team earned its second consecutive NCAA Division III Tournament berth on Monday afternoon. The Jeffs will be paired up with two-time defending champion Methodist College in the Region 1 bracket.
Amherst is coming of a stellar regular season in which they won the Hartford Invitational, Lady Eph Invitational and placed third in the Massachusetts State Championships. In Hartford, the Jeffs were paced by sophomore Kathryn Kuchefski (Wellesley, MA), who shot a 169 to place seventh overall. Junior Katie Gravel (Manchester, ME) followed her up with an 11th place performance, firing a 172. First-years Emily Foran (Dallas, PA) finished in 21st place, while Meg Sullivan (Northampton, MA) place 22nd, shooting scores of 177 and 178, respectively. Junior Jeannie Limpert (Bethesda, MD) rounded the scoring out for the Jeffs, tallying a 203.
Kuchefski finished first individually in the Lady Eph Invitational and was a critical factor in the team's first-place finish. Foran, first-year Sarah Godwin (Swarthmore, PA), and Sullivan performed tremendously, finishing second, fourth, and sixth individually with scores of 85, 88, and 89, respectively.
The Jeffs also posted a sixth place finish at the Northeast Championships this spring. Kuchefski tied for 12th place, shooting an 83 (+11). Foran followed her teammate up, finishing in a tie for 17th place with an 84 (+12). Gravel fired a two-day total of 85-86-171 to lead Amherst to an eighth-place finish at the Lady Eagle Invitational. Foran and Sullivan also shot rounds of 92-87-179 and 92-98-190, respectively, for Amherst.
Senior captain Jaime Ratner (Liberty, NY) shot a team-best 84-81, good for fifth place at the Mount Holyoke Invitational, earlier this year. Junior Kasarin Chakkaphak (New York, NY) shot a 181, taking home second place behind Limpert, in the NESCAC Individual Tournament.
The championships will be conducted May 14-17 at The Orchards Golf Club on the campus of Mount Holyoke College in South Hadley, Massachusetts. Two teams from each of the five regions were selected for the championships. Regions 2 and 3 received three individual berths, Region 4 received two individual berths, and Regions 1 and 5 received one individual berth each. The championships will consist of both team and individual competition conducted concurrently. All participants will compete throughout the 72 holes of competition. In the team competition, the low four scores from each team for each day will count in the team's total score.


text:
The Princes Exchange Centre is sited in a landmark seven-storey contemporary, glass building at a prestigious address overlooking the River Aire. It is in central Leeds next to the financial district where neighbours include major high street banks, solicitors and accountants and the city's main railway station.
As well as having a modern, striking design, this building offers fabulous views across the bustling city centre and is next to footpaths for enjoyable riverside strolls. Leeds is the capital of the Yorkshire and Humber region and one of the leading business locations in Europe.
Thanks to its diverse economy it has been able to survive and recover from economic downturns better than many other European cities. Over the last decade, developers have been re-shaping the city's skyline with major investment projects and the value of the city's economy is projected to grow by over a quarter in the next 10 years.
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text:
Alumnus seeks students' marketing ideas for his Go Ape adventure course
Marketing instructor Don Lavin was more than happy to help – in fact he incorporated the real-life assignment as a question in his marketing final exam. And D'Agostino, USA Go Ape managing director, came to class to brief students about the enterprise he and his wife Jenny brought from the UK, where its 27 courses are wildly popular.
Go Ape features five zip lines, Tarzan swings, bridges, trapezes and rope ladders on a treetop course that spans six acres. The D'Agostinos are partners in the U.S. with the British firm that started and owns the UK courses. They discovered the "Live life adventurously" courses while working in London – Dan as a project manager with the 2012 London Olympics and Jenny as a forensic accountant.
"We believe in permission marketing," D'Agostino said during his class presentation, which included a run-down of guest demographics, price and course details. "We won't force an ad in front of you. Instead, we're asking if we can give you a banana and a card that hopefully steers you to our Web site and then to the course."
As a result of pre-opening marketing, which centered on PR and D'Agostino's stint as a Metro-stop gorilla instead of costly advertisements, the Go Ape Web site crashed and the first month sold out. In fact, D'Agostino told the students that the first year has been highly successful with 12,000 guests swinging in the tree canopy at the Rockville, Md., course.
"We rely on word of mouth – but first we have to bring the guests to us, they have to like it and then tell people about it," he said, briefly telling the students about some other marketing strategies they've implemented before turning them loose to create their own.
And create they did.
"Probably the most interesting ones dealt with business strategies, such as targeting larger and different customer segments, attracting repeat customers, and establishing partnerships with other businesses," Lavin said, after reading through the students' ideas. "They proposed tweaking prices and adding services such as baby-sitting, birthday parties and a membership club."
Others included building a miniature course for children 4 - 9 years old, targeting people to come during the week (when attendance is lower than weekends) with incentives for groups and using buzz marketing more effectively through Internet access and social networking (a Day in the Life of an Ape).
Find out more about Go Ape at www.goape.com.
Keep up to date with the Tribe on Facebook: https://www.facebook.com/GoApeUSA.


text:
The Victorian opposition has called for the looming $1 billion windfall from the sale of poker machine licences to be funnelled directly into health infrastructure projects.
The auction process to sell the gaming machine licences kicks off tomorrow and Opposition Leader
"I challenge
The government has steadfastly refused to provide any guide to the amount it will raise from the auction, arguing that to do so would simply provide buyers with a guide to price.
But Mr Baillieu said the $1 billion figure the opposition estimated would be raised through the auction process was conservative. Under the auction arrangement, bidders will pay money in instalments and Mr Baillieu said that if his party won the November 27 election it would look to employ those funds towards health capital works spending.
"We now have the unique opportunity of a financial windfall provided by the EGM licence sale,'' he said.
"These funds should be directed into health infrastructure.''
The money would come on top of any ongoing contribution from the taxes of pokie losses that currently go into the health system.
Health Minister
Mr Andrews said the $1 billion could provide only about half of the 2500 acute care beds that the opposition had estimated it could fund. The cost of providing an acute care bed was about $1 million, he said.
Mr Andrews refused to detail how the government intended to spend the proceeds from the auction, saying that would be revealed after the auction was completed.
"If you are going to indicate where you are going to spend the money, you want to be in a position [to say] how much you are going to spend,'' he said.
The announcement was the centrepiece of Mr Baillieu's address to a Liberal Party state council, the last before the state poll in November. Mr Baillieu told party members the government had become arrogant and was open to criticism on many fronts.
"We have got the party and the community talking about change and we have got a policy roll-out continuing and people are listening,'' he said.
Several senior Liberals told The Australian Financial Review that the mood within the party had improved markedly over the past six months as Mr Baillieu had scored hits on the government, particularly over law and order and the case for an independent corruption commission.
``Six months ago we were in the grandstand, now we are on the ground competing and it is amazing what a difference that makes,'' one Liberal said.
The Australian Financial Review


text:
2014-08-17 Summer Sonic 2014 (Queen + Adam Lambert)
From Adam Lambert Live
|Date: August 17, 2014
Event: Summer Sonic (Queen + Adam Lambert)
Type: Concert
Televised: Yes (Partial)
Venue: Marine Stage, QVC Marine Field
City: Chiba (Marketed as Tokyo)
Country: Japan
The second of two Queen + Adam Lambert headlining concerts in Japan for the dual-city Summer Sonic festival. The concert was performed in front of an audience of approximately 50,000[1] at the QVC Marine Field (a.k.a. Chiba Marine Stadium).
- Like the previous Osaka concert, the setlist for this show is shortened to fit the festival's time constraints, but with differences: "In the Lap of the Gods… Revisited" and "I Want It All" reappear, replacing "Somebody to Love" and "Who Wants to Live Forever".
- Brian again takes another selfie with the audience during his solo segment.
- Unlike Osaka, Adam does his usual costume changes for this concert.
- At the end of the concert, fireworks go off as the "God Save the Queen" outros play in the background.
- Now I'm Here
- Stone Cold Crazy
- Another One Bites the Dust
- Fat Bottomed Girls
- In the Lap of the Gods… Revisited
- Seven Seas of Rhye
- Killer Queen
- I Want It All
- Teo Torriatte (Brian)*
- Love of My Life (Brian)*
- These Are the Days of Our Lives (Roger)*
- Under Pressure (Roger/Adam duet)
- I Was Born to Love You
- Radio Gaga
- Crazy Little Thing Called Love
- Bohemian Rhapsody
- Encore: We Will Rock You
- Encore: We Are the Champions
*Adam does not perform these songs.
- Terra's YouTube Playlist
- @mmyy9's Video List
- Summer Sonic Tokyo Official Photo Gallery
- Musicshelf: クイーン+アダム・ランバート、来日公演成功
- The Japan Times: Old and new mingle sweetly at Summer Sonic
- Complete concert audio from "Once in this Lifetime" (excellent pro-quality IEM + Audience audio): Direct Download Links for FLAC and 320kbps MP3 (password: iwbtly) [2] *NEW*
- Concert audio recording by @InesFuchsia in 96kHz 24bit WAV | Listen
- Complete concert audio by Masahiko: Queenzone Torrent[3]
- Multicam edit of concert by Mark Bowles (Marknow)
- HD1080p compilation of televised footage of the band at the airport, backstage and "We Are the Champions" snippet, aired on 16 and 17 August 2014 (6 Mbps MPEG-4 AVC with 192 kbps AAC)
- HD1080p televised footage of "Now I'm Here", "Stone Cold Crazy" and I Was Born to Love You", aired on 27 September 2014] (12 Mbps MPEG-4 AVC with 128 kbps AC3)
- ↑ Source: Musicshelf.
- ↑ Source: Matrix of Adam's IEM audio with an excellent audience recording.
Lineage: Original CD > EAC > CD Wave (to adjust track split points) > FLAC Level 8
- ↑ Recorded on location by Masahiko (left block of Marine Stage; relatively close to the main speaker).
Lineage: Adphox BME-200 binaural microphones & earphone > TASCAM DR-07 MKII (WAV 96kHz/24-bit w/ 40Hz low cut filter) w/ Transcend 32GB microSDHC Class 10 Memory Card > PC via USB > Audacity (normalising, track splitting, fading) > Trader's Little Helper > FLAC Level 8


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The threat of a federal government shutdown comes less than two weeks till tax day. But don't expect a reprieve. You're still on the hook — even though the IRS might not be able to answer your questions or process your refund. One thing it would still do? Cash your checks.
Would I still have to file my tax return by April 18?
Yes, says Internal Revenue Service Commissioner Douglas Shulman. "File your tax returns," he told reporters Wednesday. A tiny silver lining: You do have three more days than normal this year. That's because a District of Columbia holiday — Emancipation Day, which celebrates the freeing of slaves in D.C. — falls on Friday, April 15. Otherwise, the normal rules apply: Your return must be postmarked no later than April 18. You can request an extension, but you still must pay what you owe or face penalties.
Does it matter whether I file electronically or on paper?
Yes. To avoid a delay in your tax refund, file electronically. Those tax returns would still be processed if there's a shutdown, said Michael Dobzinski, the IRS spokesman for Florida. Meanwhile, the agency wouldn't be able to process paper-filed tax returns, delaying refunds. "If there is a shutdown, tens of millions of hardworking taxpayers will have to wait months to get their refunds," said Patrick Cox, CEO of Taxmasters Inc. Only about a third of returns were filed on paper last year, according to the IRS, and it's expected to be even less this year.
Would the IRS still cash my check?
Yes. Shulman told a House subcommittee last week that the agency's old plan, developed during the 1990s, called for depositing checks but not actually processing returns. Sandra Salstrom with the U.S. Treasury confirmed Thursday that's still the case. Why? The government needs the money. "If they're not going to open the returns and process the checks, they would run into the debt ceiling fairly quickly," Lou Crandall, chief economist of Wrightson ICAP, told Bloomberg News. Still, that doesn't sit well with Sen. Bill Nelson, D-Fla. "That needs to be fixed," he said Thursday. "Otherwise it's heads the IRS wins; and tails the taxpayer loses."
Would the IRS still answer my tax questions?
Perhaps not, according to a memo from the Office of Management and Budget released Thursday by Nelson's office. "Many taxpayers would be unable to receive service from the IRS to help them meet their tax obligations," it said. "For example, 400 walk-in service centers would be closed." However, tips and information would still be available from IRS.gov, not to mention private tax preparers, nonprofits and trained volunteers. "This is business as usual for us," said Gene King, a representative of H&R Block. "We've managed many instances of late legislation, filing delays and other operational challenges during our 56 years of preparing taxes."
Would local taxpayer assistance centers stay open?
It's not clear whether centers at 9450 Koger Blvd. in St. Petersburg and 3848 W Columbus Drive in Tampa would stay open during a shutdown. "Operational plans are still being finalized," Dobzinski said. To be safe, seek help now. They're open weekdays, 8:30 a.m. to 4:30 p.m., and are also scheduled to be open Saturday, April 16 from 9 a.m. to 2 p.m. There's no appointment needed to speak to someone in person. For more information about tax help, call them at (727) 568-2459 or (813) 348-1831. There are also volunteers who help low- to moderate-income taxpayers. To find the VITA site nearest you, call toll-free 1-800-906-9887 or visit IRS.gov. If you're 60 or older, there's even more assistance. Call toll-free 1-800-829-1040 or 1-888-227-7669.
How many people still need to file their taxes?
Less than half of all taxpayers, according to the IRS. Two weeks ago, it had already received more than 82 million individual income tax returns, nearly 60 percent of an expected 141 million. About a quarter of taxpayers normally wait till the last two weeks to file.
Information from Bloomberg News was used in this report. Becky Bowers can be reached at email@example.com or (727) 893-8859.


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Using Data to Discover the Value of Interconnected Relationships
For over 175 years, we've been passionate about what the power of data can do to help grow companies.
But data alone is not enough.
Creating growth is dependent on how you use insights and information to deepen and recognize the opportunities hidden in your relationships with your customers, prospects, suppliers and partners. By identifying the most valuable relationships within your data, you'll be able to model behaviors and predict smarter outcomes that lead to better results. These decisions will ultimately affect the success – or failure – of your business. That's why we've compiled the most comprehensive and accurate repository of business data on the planet – to help supplement your existing information so you have a more informed understanding of who you're doing business with.
Why Relationship Data?
Understanding the way in which two or more entities are connected is the foundation of relationship data and is at the core of what we do. Working closely with you, we deliver insights that emerge when information about two or more entities are brought together along with their business activities, which can then inform an implied business impact or outcome.
The more you connect and expose entities across your silos, the greater your visibility into the cross-company interactions with customers and suppliers. Your ability to uncover previously hidden associations inside the data provides a catalyst for business transformation and insights. Exposing relationships across product lines, branches and countries creates opportunities to evaluate sales coverage, modify compensation plans, renegotiate terms and conditions, adjust compliance policies, improve customer experiences, build advanced segmentation categories and uncover hidden supply chain risk.
The deeper you go in connecting the associated entities and the information that aligns to their business practices, the richer the insights we deliver.
Key Benefits:
- 360-degree view of every internal and external business touch point
- Breaks down reliance on data silos
- Delivers new insight into an entity's family tree
- Deeper visibility into your supply chain
- Identifies the potential for malfeasance, fraud and risk
- Enables you to develop more accurate business models
Bringing Relationship Data to Life
A true relationship data platform is created when our proprietary data is combined with your data and integrated into your native workflow systems to optimize the platform for insight discovery. Then and only then, does relationship data come to life to be used across your organization.
Our data was specifically architected to seamlessly integrate into any native workflow, business process or application such as Salesforce, Sugar, Oracle, etc., no matter the size or scope. Delivered through flat files or through an API, we empower your company to gain an understanding of the ultimate potential of relationships with customers, partners and suppliers.
The Relationship Data Cycle
While the Relationship Data Platform is created by combining our data with your data across your native workflows, it starts with the data we collect from over 30,000 business sources. We've developed a closed loop process that involves collecting, cleansing, matching and enriching data, which in turn delivers unmatched scope, flexibility and reliability for our customers. Within this cycle lies our patented DUNSRight™ process, which enables us to turn an enormous stream of data into high quality business information. This comprehensive cycle ensures you are accessing the optimal insights needed to successfully match and link data to the appropriate entities for consistency and standardization across the globe.
Click here to learn more about the 5-step Relationship Data Cycle.
Our Data Differentiators
Our ability to identify and connect business relationships is powered by over 30,000 global data sources updated 5 million times per day, including:
- Credit scores and rating
- Over 1B trade experiences
- 3M corporate family trees
- Banking data
- Firmographics
- Social Signals
- Business registrations
Not only do we aggregate and compile the most accurate and comprehensive repository of business-class data on the planet, we employ a system of techniques and process while leveraging unmatched expertise to turn the data into insights that will help you stand apart.
- DUNSRight™ Process: Our proprietary process where we collect, aggregate, edit, and verify data from thousands of sources daily so that our customers can use the information to make profitable decisions for their businesses.
- Privacy & Compliance: The privacy and security of data is our main concern, and an area of significant, ongoing investment across the company so you can do business with confidence.
- Breadth/Depth of Data: We draw intelligence from thousands of data sources to deliver unique, unbiased insights you can apply to your growth strategies.
- Worldwide Partners: We're constantly exploring partnerships with leading technology providers to deliver our best-in-class data natively into the core platforms at the heart of the modern enterprise.
- Unrivaled Experience: Our purpose is to grow the most valuable relationships in business by uncovering truth and meaning from data. We are wildly passionate about this purpose, and it has us evolving everything we do.
- Our Global Customers: 90% of the Fortune 500™, and companies of every size around the world, rely on our data, insights and analytics to streamline operations, manage risk, improve targeting, find quality leads, boost customer relationships and – most important of all – grow.
Substantial Benefits for Today's Data-Inspired Leaders
- Chief Data Officers get a comprehensive, flexible platform to integrate with tools and cloud-based applications that provide the right information to the right function at the right time. Our customers have seen data integration time improve by up to 30%. Learn more about solutions for CDOs
- Chief Marketing Officers access a single, unified, end-to-end view of increasingly self-directed prospects. Our customers have increased conversion rates up to 12%, improved campaign performance up to 15% and enhanced targeting effectiveness by up to 30%. Learn more about solutions for CMOs
- Chief Financial Officers have comprehensive customer intelligence to quickly make the right calls on allocating credit and investing capital. Our customers have been able to reduce outstanding sales timeframe by up to five days. Learn more about solutions for CFOs
- Chief Procurement Officers develop the optics necessary to anticipate supplier risk, optimize the entire chain and maximize buying power. Our customers have reduced supply chain risk up to 30% and reduced costs of certifying new vendors by up to 15%. Learn more about solutions for CPOs
- Chief Compliance Officers own a single source of information, analysis and expertise to drive their compliance processes. Our customers can reduce due diligence time by up to 50%. Learn more about solutions for CCOs


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Altered Book: orange.blue rev 2.0/
"Live in the sunshine,
swim the sea,
drink the wild air."
~ Ralph Waldo Emerson
I'm not sure if it's the colors or the images, but this reminds me of walking along a chilly beach, collecting shells. The quote is amazing -- I like how it fits with how I see the page.
Most of us create art journal pages ultimately for ourselves (or maybe I'm naive and many create their pages to sell, I'm not sure) so it's crucial to "get something" out of each page. Get something from the experience of playing with paints and materials, get thoughts/feelings out of your head and onto the page, get inspired by the finished page... what do you "get" out of your pages?
Here's the original: Altered Book orange.blue.


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Search and Seizure - The Search Warrant Requirement
officer evidence items particular
A SEARCH WARRANT is a judicially approved document that authorizes law enforcement officials to search a particular place. To obtain a search warrant, a police officer must provide an account of information supporting probable cause to believe that evidence of a crime will be found in a particular place or places. The officer must also make a list of the particular places to be searched and the items sought. Finally, the officer must swear to the truthfulness of the information. The officer presents the information in an AFFIDAVIT to a magistrate or judge, who determines whether to approve the warrant.
An officer may search only the places where items identified in the search warrant may be found. For example, if the only item sought is a snowmobile, the officer may not rummage through desk drawers. Only the items listed in the warrant may be seized, unless other evidence of illegal activity is in plain view. Judges or magistrates may approve a variety of types of searches. The removal of blood from a person's body, a search of body cavities, and even surgery may be approved for the gathering of evidence. ELECTRONIC SURVEILLANCE and phone records may also be used to gather evidence upon the issuance of a warrant.
A warrant is not required for a search incident to a lawful arrest, the seizure of items in plain view, a border search, a search effected in open fields, a vehicle search (except for the trunk), an inventory search of an impounded vehicle, and any search necessitated by exigent circumstances. It is also not required for a STOP AND FRISK, a limited search for weapons based on a reasonable suspicion that the subject has committed or is committing a crime. A police officer may also conduct a warrantless search if the subject consents.


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Arriving back on the west coast, Natalie Portman landed at LAX Airport on Friday evening (January 25) in Los Angeles.
Clad in all black with her hair pulled into a bun, the "Black Swan" beauty was accompanied by her husband, Benjamin Millepied, as she made her way through the busy terminal.
They've become tired of the hustle and bustle of Hollywood, and now Natalie Portman and her husband Benjamin Millepied are setting their sights on the City of Lights.
Millepied just signed on with the Paris Opera Ballet as the new director of dance, effective September 2014, so they'll be packing up their son Aleph and headed to France.
Taking care of some business, Natalie Portman arrived at LAX Airport on Wednesday afternoon (January 23) in Los Angeles.
Dressed against the unusual California chill in leggings and a black coat, the "Black Swan" beauty quickly left the busy terminal and headed to her vehicle.
Checking some items off of her to-do list, Natalie Portman was out and about in Santa Monica on Monday afternoon (January 21).
Casually clad in black pants and a black sweater, the "Thor" beauty carried a large polka dotted tote bag as she ran her errands on the sunny day.
Stepping out for a few essentials, Natalie Portman carried her groceries out of Gelson's Market in Los Feliz, CA earlier this afternoon (January 18).
The "Black Swan" actress donned a pair of moon boots with a light jackets as she trekked through the store's parking lot.
Filling her day with family fun, Natalie Portman spent Monday afternoon (January 14) at the community center gym in Los Feliz with her son Aleph.
The 31-year-old actress opted for a comfortable ensemble as she chatted with other moms in the gym's parking lot.
Making sure to socialize her little boy, Natalie Portman took Aleph on a play date in Pasadena, California on Friday (January 11).
The "Black Swan" star wore a blue jacket and jeans while she carried her adorable 1-year-old boy, who sported an orange coat and sneakers.
2012 was the year of the ladies at the box office, with the top two on Forbes list of Hollywood's Best Actors for the Buck being women.
"Black Swan" star Natalie Portman topped the list, returning $42.70 for every dollar a studio spends on her.


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Standard treatises on mergers & acquisitions (M&A) contain the usual benefits or rationale for why a company would take over another. These include growth, size, synergies, and so on. One of the significant benefits of takeovers could also be tax synergies such as setting off the losses of one company against the losses of another. Similar benefits may be available with respect to unabsorbed depreciation and other capital allowances in the loss-making company.
In recent times, a whole new tax rationale has been driving M&A activity in relation to US companies, and that is to achieve relocation of U.S. businesses into other jurisdictions so as to minimise the effect of exorbitant U.S. taxes. This is accomplished through "inversion" deals. "Inversions" are described in the Wall Street Journal as follows:
Inversions enable a U.S. company to lower its tax rate. In these deals, a U.S. company buys a foreign target and adopts its home country's domicile, or the combined company establishes a holding company in a country with a low tax rate. U.S. companies can lower their tax rate to the single digits from as much as 35% through an inversion.
An explanatory video is also available through the M&A Law Prof Blog.
Inversion deals have become quite common in the pharmaceutical and healthcare sectors, with Ireland and the Netherlands becoming common destinations for U.S. companies to relocate to. The deal that has been making waves is U.S. company AbbVie's proposed acquisition of Shire PLC for US$ 54 billion (as discussed here and here).
Inversion deals give rise to greater concerns in countries such as the U.S. where not only are tax rates high but even the global income of U.S. companies are subject to taxation. There are potentially two ways to deal with this issue. One would be to impose legal restraints on inversion deals, a matter that the U.S. government appears to be seriously considering. The other is a more permanent solution to streamline and minimise the adverse impact of taxation on U.S. businesses.
The issue of reincorpoation and corporate migration is not limited to taxation concerns. Reincorpoations may occur due to other reasons, including onerous regulation in home jurisdictions. Hitherto, concerns had been expressed even in the Indian context due to policy paralysis and overarching legal regulations that led to a few companies relocating from India to other jurisdictions such as Singapore. Now that the Companies Act, 2013 permits Indian companies to amalgmate into foreign companies in reciprocating territories, relocations could very well be implemented through that method.
While inversion deals and cross-border mergers could provide sufficient flexibility to companies to manoeuvre around burdensome taxation or other regulation, equally there exists the concerns as to whether it leaves too much room to engage in tax or regulatory arbitrage through competition amongst various jurisdictions that might lead to a "race to the bottom".


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The google search app is installed through play store and is up to date. The toggle to enable google now is not there whatever i try.
I have tried unistalling and re-installing, reseting its data, clearing the cache, wipeing data through titanium backup, wiping Cache's through recovery etc. nothing seems to work for me.
Any help appreciated.


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A group from UAE Outstanding Students, part of the Hamdan Bin Rashid Al Maktoum Award For Distinguished Academic Performance, has visited the Jordan University of Science and Technology. The students were received by Professor Wajih Owais, President of the university. According to <i>WAM</I>, Professor Owais briefed the students on the university and its different sections. More than 3,000 students of different nationalities are currently enrolled in this university.
[1] http://www.albawaba.com


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When the sheriff-to-be is killed, the man assumes his identity, Lucas Hood, and becomes the new Sheriff of banshee.
The first season of banshee, meanwhile, was completely outrageous (in a good way).
When you're going right it sounds a pass between a peanut roaster and a banshee with bronchitis.
But that was the last act of destruction that the banshee was destined to accomplish.
She dug her little heel into the ground to show how she would crush the banshee.
The banshee corked the bottle and held it up proudly to the light.
The figure waved her arms towards the house, and my mother heard the bitter wailing of the banshee.
I thought it might be a banshee, if thair is that crayther in this counthry.
Presently he heard the long-drawn, quavering, banshee wail of a locomotive.
He marched his men up, with the thin wailing of a banshee in his ears.
1771, from phonetic spelling of Irish bean sidhe "female of the Elves," from bean "woman" (from PIE *gwen-; see queen) + sidhe, from sith "fairy" or sid "fairy mound." Specifically, one who calls to the spirits of the dead.


text: Burts Bees Very Volumizing Shampoo This Very Volumizing Shampoo from Burts Bees works to inject the hair with beautiful bounce and body, improving the hairs volume and fullness. A gentle, natural shampoo, this product is enriched with Pomegranate Oil and Jojoba Protein to ensure that your hair gets only the best care. A natural moisturiser, this shampoo gives you salon perfect, healthy looking hair. Naturally moisturises with Pomegranate Seed Oil and Jojoba Protein Adds shine to hair Smoothes and reduces frizzCheck stock and price


text:
No Celebrity Endorsement Implied
Humiliated, she retreats to Malibu with her 5-year-old daughter. Her friends face their own problems. Joan (Judy Davis) has secretly entered rehab, Rodney's (Chris Diamantopoulos) interior design career is on life support, and Cricket's (Miranda Otto) relationship with her husband, Jorge (Aden Young), is struggling.
Cut off from the world she knows, Molly begins to reevaluate her
life, and a near death experience leads to an encounter with a handsome
stranger named Sam (Stephen Moyer.)
Spurred on by her brush with death and intrigued by her chemistry
with Sam, Molly decides to re-invent herself. She focuses on being a
better mother, and after receiving unexpected attention from Kenny's
boss, Lou (Joe Mantegna), she boldly invites him over for dinner.
When Lou doesn't show up, Molly shares a perfect kiss with Sam.
Meanwhile, her friends' struggles continue as Joan grows weary of rehab
and Cricket's husband has a secret tryst with their nanny.


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I just found this plugin.It's Particle Rendering, Manipulation and Management Toolkit for Autodesk 3ds Max.
Hope many designers will know about it but if you haven't heard about it then just watch the preview below which was made with the plugin krakatova
There is no "v" dude. It's a beauty.
Holy F**k. Thats amazing!
Me like.
InlifeThrill said
There is no "v" dude.
Sorry about that.
addey, all good dude
If they do release a standalone version, as said in their website, I'd be tempted to try it out . Much like an improved particular indeed. Looks like ton of fun (and math..)
As far as I understood it, it's more of an addon to 3ds max's particle flow ( or any other particle plugin. like thinking particles). It's sort of render engine for particles where it multiplies number of particles with all sort of rules. By doing so it gives much denser particle creations. But might be wrong here.
I guess the main problem with Trapcode is that the behaviour of particles is fairly simplistic… certainly regarding turbulence and so on. Of course, the joy is that you can do without the agonizing render times of fluid simulations.
I'd guess that this is a similar system, but some of the simulations do look very convincing. I wonder how quick it is (and what it will cost).
Fluid sim wise, there's Turbulence for C4D at €399, DPIT at €700. Blender for free.
If you're a 3DS or Maya sort, FumeFX'll set you back €1000 and if you have just inherited millions from a long lost aunt, then Realflow's gotta be your tool of choice at a mean €5000.
Are there any more we can think of?


text:
Your browser or your browser's settings are not supported. To get the best experience possible, please download a compatible browser. If you know your browser is up to date, you should check to ensure that
› Learn How
The opening drag chute slowed Endeavour as it landed on runway 15 at NASA's Kennedy Space Center. The Endeavour crew, led by Commander Scott Kelly, completed a 13-day mission to the International Space Station. The STS-118 mission began Aug. 8 and installed a new gyroscope, an external spare parts platform and another truss segment to the expanding station. Endeavour's main gear touched down at 12:32 EDT, on Aug. 21, 2007, after traveling more than 5 million miles. Image credit: NASA/George Shelton


text:
World War II
Staff Sergeant, U. S. Army. Home address: Sallisaw, Sequoyah County. Mrs. Delilah Claunch, Mother, Sallisaw. Born April 5, 1911. Enlisted August 11, 1943. Graduated from Central High School, Sallisaw. Attended Connors State Agriculture, Warner, and Northeastern State College, Tahlequah. Member of First Baptist Church. Died February 21, 1945, in action in France.
Oklahoma Historical Society
Oklahoma History Center | 800 Nazih Zuhdi Dr. | Oklahoma City, OK 73105


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I am strong physically , balanced emotionally and have big ideas for life.
Socially easy to be with unless you try to screw me over.
I am coming from Madrid Spain. I am chilled person for to be a latin.
Si te gusta aprender algunas palabras en español, podemos hacerlo juntos.
Worked years as life guard around the world.
I also did modelling for some fashion shoots.
Helping also others to making their dreams come true when I am motivating them to pushing limits.
there is something that I am not that good, like school book stuff.
BTW for few those disbelievers out there its ME who is in pictures.
Looking for a stud who knows what he is doing and Who has muscle to please you.
If you want really know more about me send some PM so I can reveal some private things and pics.


text:
As Hess Corp. prepares to spend $650 million building a 625-megawatt natural gas-fueled power plant in Newark, the firm is asking federal regulators to solve a dispute that could save the company $13.5 million. But doing so would require the regional grid operator to approve equipment adjustments that so far, they've refused to do.
Energy regulations require power companies to pay the cost of connecting their plants to the grid, including any equipment upgrades necessary to accommodate the new power. An analysis from PJM Interconnection LLC, which operates the region's power grid, shows Hess' Newark Energy Center would require the replacement of a transformer in Essex County at a cost of $13.5 million, among other upgrades. Hess, however, believes a minor adjustment to a piece of equipment called a phase angle regulator, or PAR, would negate the need to replace the transformer.
Tamara Linde, vice president of regulatory issues at Public Service Enterprise Group, said PARs help direct the flow of power. PSEG is the parent company of PSE&G, which owns the transmission facilities Hess is planning to connect to.
"Normally, power flows in the path of least resistance," Linde said.
A PAR doesn't create any new transmission capacity on the grid, Linde said, but it can be used to allocate the flow of power, and manage the burden on existing facilities.
Each year, PJM undertakes a baseline analysis of its entire grid, determining the best settings to keep the system from becoming overloaded. Temporary adjustments to those settings can be made to deal with spikes in demand, but longstanding policies call for the use of the baseline settings when determining the impact of a new plant coming on line.
Paula DuPont-Kidd, a PJM spokeswoman, said making an adjustment for Hess would upset the interconnection process and require PJM to recalculate all of the data for the other projects in the interconnection queue.
"That would be, in our opinion, unfair to other customers and other members, and it wouldn't be an efficient way to do our planning process," DuPont-Kidd said.
Linde, of PSEG, said making such a change also could limit the way PJM uses PARs, and establish a precedent whereby every new generator seeks adjustments.
Exelon Corp., Baltimore Gas & Electric and Dominion Resource Services each have filed documents supporting PJM's position.
In October, Hess filed a complaint with the Federal Energy Regulatory Commission, asking the commission to rule that PJM has the right to make an adjustment for Hess. If not, Hess is asking FERC to change the rules to allow for such adjustments.
"These angle adjustments are so minor that, as a practical matter, the capacity that can be made available through PARs to manage congestion … would essentially be the same both prior to and after the interconnection of the Newark Energy Center," wrote Sunil Talati, president of the energy consultancy PwrSolutions Inc., in written testimony on behalf of Hess.
Hess's position is supported by New Jersey's Board of Public Utilities, which has sought to encourage the construction of new power plants in the state as a means to lower energy costs. The BPU filed a motion supporting Hess and calling the adjustments reasonable, particularly in light of the high cost of connecting to the grid: Hess faces an estimated $112.5 million in interconnection costs, in addition to the $13.5 million in dispute.
"It is therefore critical that PJM ensure interconnection studies accurately reflect only the most necessary infrastructure upgrades required to ensure reliability," the BPU wrote.
Hess is one of three generators included in the state's controversial Long-Term Capacity Agreement pilot program, under which the state could potentially help subsidize the new plant. PJM and PSEG both opposed LCAPP, and FERC has twice ruled against parts of the program.
Hess has asked FERC for an expedited decision — no later than Feb. 1 — so the generator has time to decide whether to enter the base residual auction, in May, at which the company could bid to sell power beginning in 2015. A company official told NJBIZ a negative ruling from FERC wouldn't affect the company's decision to go forward with the plant.
If Hess wins its case, PSEG fears ratepayers could be on the hook for $13.5 million.
"Our view is that shifting the PAR would only eliminate the need in the planning study, but in reality, the power from the Hess plant would still flow over the line, causing violations — and the line will still need to be upgraded," said PSEG spokesman Michael Jennings. "If Hess is not paying for that, someone else will need to."
DuPont-Kidd said it's difficult to tell what upgrades may or may not be needed if Hess wins its case, or how the costs would be allocated.
Hess, for its part, argues ratepayers already paid for the existing transmission facilities; therefore, it's only fair for every company to have equal access to the equipment.
E-mail to: email@example.com
On Twitter: @JaredKaltwasser


text:
That's really great!!! My item also move in new category. Have you anyone face sorting problem?
I just noticed my paw was changed to "Red".
Really thanks to this great community. && My Hearty thanks to buyers. I can't achieve this without them
You can also share your milestone here.
Thanks a lot!
Superb…. Congrats!!
Rebirth Pixel | http://www.behance.net/rebirthpixel
Thank's to all, thank's envato community.
Thanks a lot!!!
My next project: UI Pack for iOS VOL – II


text:
Conceptual Structures: Theory and Implementation : 7th Annual Workshop Las Cruces, Nm, Usa, July 8-10, 1992 : Proceedings (Lecture Notes in Computer Science)
This volume contains revised and expanded versions of papers presented at the Seventh Annual Workshop on Conceptual Graphs, held at New Mexico State University in Las Cruces, and sponsored by the American Association for Artificial Intelligence and the NMSU Computer Science Department. The contents of the volume fall in the areas of representation issues, reasoning, data modeling and databases, algorithms and tools, and applications and natural language. One of the highlights reported in the volume is the landmark meeting of the first PEIRCE Project Workshop. The PEIRCE Project aims to build a state-of-the-art, industrial strength conceptual graphs workbench.
Please visit Help Page for Questions
regarding ISBN / ISBN-10 / ISBN10, ISBN-13 / ISBN13, EAN / EAN-13, and Amazon
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text:
The use of special surveillance devices (SSD) is still illegal in Bulgaria and both producer Howard Bradburn and reporter Justin Rowlatt had worn them while filming Ivan Slavkov explaining how he could he London win votes for its bid for the 2012 Olympic Games.
The additional charge of incitement to corruption was based on the argument that it was the BBC who had been trying to encourage Slavkov into being corrupted rather than attempting to expose him as already corrupted.
Andrew Jennings, who worked as a consultant to the programme, said that the accusations made Bulgaria look laughable to the outside world. Slavkov's response to Jennings' comments on the case was to call him "homosexual".


text:
Religion 204b
Scripture in Judaism, Christianity, and Islam
Spring 2008 MWF 9:30-10:20
Instructor: Jonathan Brumberg-Kraus, x3694, (H): 401-273-0536; e-mail: jkraus
Office Hours (Knapton 102): M 10:30-12:30, 1:30-2; W 10:30-12:00; F 10:30-12:30, and TuTh by appointment.
This course focuses on the religious function of sacred scriptures in the three Western religious traditions: Judaism, Christianity, and Islam. Attention will be paid to scripture as myth of origins, the relative importance of sacred story, prophecy, and law in the three traditions, authority, and the importance of interpretative traditions. We will also investigate the ritual functions of Scripture, artistic representations, and contemporary efforts to interpret the relevance of textual traditions.
Texts Required for Purchase:
John Corrigan et al., Jews, Christians, Muslims: A Comparative Introduction to Monotheistic Religions
Barry Holtz, ed., Back to the Sources
Oxford Study Bible
Michael Sells, Approaching the Qur'an: The Early
Revelations (book and CD)
Samuel Proctor, How Shall They Hear?
William Graham, Beyond The Written Word: Oral Aspects Of Scripture In The History Of Religion
Amina Wadud-Muhsin, Qur'an and Woman
On Reserve:
Jo Milgrom, Handmade Midrash
N.B.: All required and recommended texts, as well as the texts in the Reading Packet, have been placed on 2 hr. reserve in the Library. Asterisked (*)readings are optional, not required
Introduction: What is Scripture?
1/23 First Day of Class
Scripture from a Comparative Perspective
Scripture as a "relational concept"
1/25 Friday: Read William Graham, "Scripture," Encyclopedia of Religion, ed. M. Eliade, v. 13:133-145
Unit I: Scripture in Judaism
A. The Torah: Sacred Story + Sacred Law
Biblical Narrative
1/28 Monday: Read Genesis 1-11; Jews, Christians, Muslims (JCM), 3-14]
1/30 Wednesday: Read Genesis 12-27
2/1 Friday: Read Holtz, BS, pp. 31-81
Biblical Law
2/4 Monday: Read Leviticus 1,6-8,9-11, 19-20; Holtz BS, pp. 83-103
2/6 Wednesday: Read Exodus 19-20; Deuteronomy 6-7, 26-28
B. The Oral and Written "Dual Torah" of Rabbinic Judaism
2/8 Friday Read JCM, 15-25; 282-294; See the video The Talmud and the Scholar (about Rabbi Adin Steinsaltz, spirituality of Torah study)
2/11 Monday: See the video Half the Kingdom (feminist perspective on women's roles in Judaism)
Read JCM, 215-226; *Vanessa Ochs, Words On Fire (RP Text F, pp. 29-68)
2/13 Wednesday: Read Holtz, BS, pp. 177-204; Lamentations, Lamentations Rabbah (RP-Text B)
2/15 Friday: Read Exodus 1-6; selections from Exodus Rabba; Lawrence Hoffman,"Sacred Myths: Pre-Modern Jewish Perspectives," Beyond the Text (RP-Text C)
Kabbalah (mysticism): Torah as the Name of God
2/18 Monday: Read JCM, 77-92; G. Scholem, "Revelation and Tradition..."(RP Text D); Selections from Sha'arei Orah ("Gates of Light") (RP Text E)
Midterm Study Guide
2/20 Wednesday: Read JCM, 92-104; 227-234
C. Contemporary Applications
1.Study = worship
2. Feminist appropriation of Torah;
2/22 Friday: Read Vanessa Ochs, Words on Fire (RP Text F, pp. 101-131)
Field trip to Synagogue. Specifics TBA.
2/25 Monday Midrash Assignment due
Review for Midterm Exam
Unit II: Scripture in Islam
A. The Qur'an
2/27 Wednesday: Read JCM, 52-72, 134-151; Sells, Approaching the Qur'an, pp. 1-35; NY Times article by Tariq Ramadan (on Blackboard)
2/29 Friday : Recitation of the Qur'an: Qur'an in Ritual
Read Sells, Approaching the Qur'an, pp. 145-183; W. Graham, Beyond the Written Word: Oral Aspects of Scripture, pp. 79-115; listen to recitations of the Qur'an on the CD in Sells.
3/3 Monday:
Midterm Exam
3/5 The Form and Style of the Qur'an
Read Sells, Approaching the Qur'an, 42-145 (selections to be assigned to different groups of students)
B. Classical Islamic Transformations
1.Visual Representation in Art and Architecture
3/7 Friday: Slide Presentation
Read JCM, 397-416; RP-Text U. Oleg Grabar, "The Symbolic Appropriation of the Land," and "Islamic Attitudes Towards the Arts," The Formation of Islamic Art
3/10-3/14 Spring Break – No Class
3/17 Monday: Calligraphy
Read the WWW site: Islamic and Arabic Arts and Architecture - Calligraphy
Islam assignment due 1)Hand in Basmalah calligraphy Monday 3/24
2) Make appointment to recite Fatiha during office hours 3/24 -3/28
2. Philosophical Transformations
3/19 Wednesday: Read JCM, 195-209; RP-Text T. Averroes, The Decisive Treatise, Determining What the Connection is Between Religion and Philosophy; W. Graham chapter on tafsir, Beyond the Written Word: Oral Aspects of Scripture, pp.?
Thursday Night 3/20 Field trip to Temple Emanuel in Providence, RI for Purim Services/Purimspiel. Specifics TBA.
C. Contemporary transformations: Modern Tafsir
3/21 Friday: Read Wadud Muhsin, Qur'an and Woman; Sells, pp.183-208
3/24 Monday: Read Wadud Muhsin, Qur'an and Woman
Visit to Islamic Center of New England Sunday morning TBA
Unit III: Scripture in Christianity
3/26 Wednesday: Read JCM, 26-35, 105-112; Gospel of John 1-6
3/28 Friday: Read Gospel of Mark
Early Christian Attitudes toward the Jewish Bible: Christian Scripture as "Midrash" of the "OT"
3/31 Monday: Read Hebrews, Mt 1-3; Luke 23-24; RP-Text K. Rowan Greer, "Christian Transformations of the Hebrew Scriptures," Early Biblical Interpretation
Sunday Morning – Field Trip to Trinitarian Church, Norton TBA
Going "beyond the written word"
Early Christian Prophecy
Christian Antinomianism
4/2 Wednesday: Read Galatians, Eugene Boring, "The Prophet as Hermeneut," The Continuing Voice of Jesus (RP-Text G)
4/4 Friday: Read I Corinthians
Classical Transformations of Christian Scripture
1. Allegory and Typology
4/7 Monday: Read JCM, 35-51; RP-Text L. Origen, "The Prologue to the Commentary on the Song of Songs"
2.Transformations of Christian Scripture in Other Media
Visual Representations of Christian Scripture
Christ as nursing Mother, as Food
4/9 Wednesday: Read JCM, 368-396; View slides of Chartres Cathedral
Image of Christ as nursing mother
4/11 Friday: Read RP-Text M. Caroline W. Bynum, "'...And Woman His Humanity': Female Imagery in the Religious Writing of the Later Middle Ages," Gender and Religion
Scripture in Christian worship and ritual
Musical Representations of Christian Scripture
4/14 Monday: Read W. Graham, Chapter on Martin Luther, Beyond the Written Word: Oral Aspects of Scripture
4/16 Wednesday: Read Samuel Proctor - How Shall They Hear?
Guest Speaker: Susan Mansfield?
4/18 Friday: Listen to selections from Bach's St. John Passion; read JCM, 235-255; RP text N. Jaroslav Pelikan, "'Meditation on Human Redemption' in the St. Matthew Passion," Bach Among the Theologians
4/21 2nd Day of Passover – No Class
Read Samuel Proctor - How Shall They Hear?
19th -20th Century American Transformations of Christian Scripture
4/23 Wednesday Discuss "preaching assignment", Read Samuel Proctor - How Shall They Hear?
4/25 Friday
8:30-9:20 AM sessions in the Chapel to hear student preaching assignments
Modern Interpretation of Christian Scripture; Conclusion
4/28 Monday Read RP-Text P. David T. Shannon, "'An Ante-bellum Sermon': A Resource for an African American Hermeneutic," Stony the Road We Trod (Ed. by C.H. Felder); Wednesday RP-Text Q. Richard J. Mouw, "The Bible in Twentieth-Century Protestantism: A Preliminary Taxonomy," The Bible in America (Ed. by N. Hatch and M. Noll)
4/30 Wednesday: Conclusion - Scripture compared in Judaism, Christianity, and Islam
5/1 Friday Final Review Session
Course Requirements
1. Preparation of Readings. Each student is expected to read the assignments.
2. Class participation. There will be class discussions each session based on the readings.
3. Web Blog: Short reflection writing assignments to be posted on individual blogs set up specifically for this class. See instructions on Blackboard. Students will "log" what they are learning throughout the term, and be able to comment on one another's questions and insights. At the end of each class session, I'll ask you to jot down at least one brief comment summarizing the gist of the day's class, and one question prompted by the day's discussion - and any other questions or comments you want to add. Likewise, for each reading assignment, jot down at least one brief comment summarizing the gist of the reading, and any other questions or comments prompted by it. By the Thursday of each week, post a digest of your comments and questions on the readings and class discussions on your blog - not more than 1 page, single-spaced for each week's posting. I'll ask you to do the same for each of our field trips. You should make at least 12 weekly posts. Finally, you must contribute at least ten comments to any of your fellow students' blog posts during the course of the term. These are both for your own benefit - to get you to begin to think analytically, to focus your thoughts on what you're learning, and for the class as a whole - to stimulate class discussions.
(Preparation of the readings and class participation will be evaluated primarily on the basis of your contributions to your blogs, and count for 25% of the course grade)
4. 3 Scriptural Interpretation projects (each 10%) Each unit will culminate with a project engaging students in a type of scriptural interpretation typical of the Jewish, Christian, and Muslim religious traditions. These assignments are intended to allow students to "get inside" the three traditions, to think about Scripture as if they were experiencing it from within Judaism, Christianity, or Islam. It is a chance for you to use your creative imagination; I hope you have fun with them! It is not meant to try to convert you to any of the traditions. It is only an exercise that approximates what it is like to think and feel like a religious Jew, Christian, and Muslim, to help you understand what academic scholars of religion call the phenomenology of religious experience in these 3 traditions.
Therefore each project requires an additional 1-3 page reflection paper on what you learned and experienced as you did the project, as well as the actual product you composed. You will have to hand in both the composition and the reflection paper for each to get full credit. Your compositions will be evaluated on how well you executed your work according to the conventions of the genre.
a. Compose your own Midrash (Jewish)
i. Students will be given the a scriptural selection from the Bible, Exodus 18-20. Students may choose which verse(s) from this passage to hang their midrash on, nor are you restricted to these verses. You can use any other Scriptural verse from the entire Hebrew Bible (the"Old Testament"), provided that you use at least one from Ex 18-20
ii. Use the assigned readings from Back to the Sources as resources
- for examples of midrash as formal models
- for hints about what features, ambiguities, gaps, etc. in the Biblical passage itself might be a good starting point for your midrash
iii. Alternatively, use Jo Milgrom's book Handmade Midrash (on reserve in the Library) as a guide for a midrashic art project
iv. The midrash (if written) should be no longer than 1-2 pages, typed double-spaced.
v. 1-3 page reflection paper
b. Memorize short passage from the Qur'an and Arabic calligraphy assignment (Muslim)
i. Use the Al-FatiHa pronunciation free software program to memorize the 1st Surah of the Qur'an
ii. Read the Islamic and Arabic Arts and Architecture - Calligraphy Web Site for overview, as resource information on Arabic Calligraphy
iii. Copy the letters of the Arabic alphabet and their names from a chart to be provided
iv. Copy by hand, as best as you can, the basmalah phrase (=the first verse of the Fatiha) in Arabic script. You may choose one of the scripts demonstrated on the above mentioned Web Site. You may also embellish it artistically - using the designs we've studied as models
v. Hand in your copy of the basmalah.
vi. 1-3 page reflection paper on both your memorization and copying of the Arabic Qur'an passages.
DUE MAR 24 -MAR 28: Make appointment to recite al-Fatiha during office hours, hand in basmalah, reflection paper
c. Compose and preach your own 10 minute sermon (Christian)
i. Use the guidelines spelled out in Samuel Proctor's How Shall They Hear? to compose your sermon. Your sermon should include each of the four points he says a good sermon should have.
ii. You may choose any Scriptural passages you want from the Old and/or New Testament to preach on.
iii. Time yourself so that speaking your sermon aloud lasts no longer than 10 minutes
iv. Do sermon aloud during additional early morning (8:30-9:20) sessions
v. Hand in a written text of your sermon
vi. 1-3 page reflection paper
DUE Apr 28-May 2: ORAL PRESENTATIONS (8:30-9:20 AM SESSIONS)
Written text of your sermon DUE DAY OF FINAL EXAM
5. Midterm Exam (20%) Objective and essay
6. Final exam (25%) Objective and essay
Attendance Policy: For every 2 unexcused absences after the 1st week of class, you will be penalized 1/3 grade (e.g., from A- to B+ for 2 absences; A- to B for 4 absences, etc.) off your final course grade.
Additional class meetings:
1. There will be three local field trips to visit a local synagogue, mosque, and church to observe the use of scripture in Jewish, Christian, and Muslim ritual (Sunday mornings, and Jewish evening Purim services as noted). Also, class will be invited for a meal at my home.
2. 4-5 early morning sessions Dec 4-8, 8:30-9:20 AM to hear, give final oral presentations.


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Homeschool Science Club - January 24th - pHun with Chemistry!
San Antonio Children´s Museum
pHun with Chemistry - Thursday, January 24th
Learn about chemical reactions as you experiment with acids and bases!
Homeschool Science Club
The San Antonio Children's Museum has exciting homeschool workshops available for families looking to supplement their science curriculum, explore physics, biology, engineering and more with our specialized equipment and knowledgeable teachers, and network with other homeschooling families.
For all of our exciting Home School Science dates and topics! www.sakids.org/events/HomeschoolScienceClub.aspx
When: Thursday January 24 (2:00-3:30 pm)!
Ages: 7-10 years*
Cost: $15.00 Members/$20.00 Non-Members per workshop (includes admission to program for participant and 1 adult); additional children participating $10 each per workshop
*Parents - You are welcome to drop your homeschooler off while you play in the museum with younger siblings if you'd like, but please do not bring younger siblings into the workshop. Regular Museum admission applies to siblings ($8 ages 2 and up; free for children under 2).
For more information, visit sakids.org
In order to purchase these tickets in installments, you'll need an Eventbrite account. Log in or sign up for a free account to continue.


text: NEW YORK ( TheStreet) -- TheStreet's Brittany Umar looks ahead to see what might cause some big moves in the market over the coming days.The week begins with Pep Boys ( PBY) reporting earnings after the close on Monday. Investors will be looking to see how the restructuring efforts have gone and if its new consumer focus is driving sales. Tuesday will feature LDK Solar ( LDK). The company is not expected to beat analyst expectations because negative margins continue to deteriorate. While the stock has nearly doubled in the last twelve months, H&R Block's ( HRB) revenue have declined every year since 2008. The company will report earnings on Wednesday, along with Men's Wearhouse ( MW). Thursday's big news will come when retail sales are released. The report will shed some light on what the recent consumer spending trends have been. Also reporting will be Smithfield Foods ( SFD). The U.S. Congress is currently scrutinizing a Chinese company's planned $4.7 billion takeover of the U.S.'s largest pork producer. Friday features the economic PPI report for the month of May, which highlights the pricing of products at the wholesale level. -- Written by Bret Kenwell in Petoskey, Mich. Follow @traderboy23


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This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
The Alpha-fetoprotein (AFP) derived Growth Inhibitory Peptide (GIP) is a 34-amino acid segment of the full-length human AFP molecule that inhibits tumor growth and metastasis. The GIP-34 and its carboxy-terminal 8-mer segment, termed GIP-8, were found to be effective as anti-cancer therapeutic peptides against nine different human cancer types. Following the uptake of GIP-34 and GIP-8 into the cell cytoplasm, each follows slightly different signal transduction cascades en route to inhibitory pathways of tumor cell growth and proliferation. The parallel mechanisms of action of GIP-34
Human alpha-fetoprotein (HAFP) is tumor-associated fetal protein, termed an oncofetal protein, consisting of 609 amino acids (AAs) including a 19 amino acid (AA) signal sequence [
The GIP fragment derived from HAFP has been reported to be a negative regulator of both fetal and cancerous growth and is composed of three contiguous bioactive subfragments consisting of 12 AAs (GIP-12), 14 AAs (GIP-14), and 8 AAs (GIP-8) [
The biological activities of GIP are cataloged and listed in chronological order in
By means of a global RNA microarray analysis, GIP-34 was found to down-regulate the RNA of outward flux K+ ion channels that determine cell membrane potential and conductance in MCF-7 cells (
Previous reports have documented that GIP-34 is able to suppress tumor cell growth and proliferation in various rodent and human cancer cell models [
Concerning the immune response, reports have shown that the GIP-34 and its subfragments can both regulate and invoke an immune response of the cellular type (T-cells, dendritic cells,
Regarding a receptor for GIP-34, a recent collaborative study has reported efforts to identify a GIP receptor involved in cancer cell targeting [
The biological activities of GIP-8 are cataloged and listed in chronological order in
It was a study by Defreest
Subsequently, evidence was forwarded by Andersen
In a series of sequential studies, Torres and Sierralta
In general, both the linear and cyclic versions of GIP-8 have demonstrated growth suppression in multiple different cancer cell assays [
The mechanism of action of GIP-34 being proposed is based on experimental data accumulated from multiple laboratories over the last 17 years (
Following the addition of GIP-34 into cancer cell culture dishes, the 34-mer attaches to the outer bilipid layer of the cell surface perturbing that interface and affecting fluidity of the lipid bilayer [
In order to study cell cycle events, GIP-34 was administered to MCF-7 cells for 8 days and subjected to a human global RNA microarray analysis of MCF-7 cancer cell lysates (
It has been determined that a time exposure of GIP-34 treatment was critical in order to accomplish growth cessation of cancer cells. In these reports, a single treatment of GIP-34 proved to be insufficient over a period of 7 days [
The mechanism of action of GIP-8 differs somewhat from that of GIP-34 regarding its inhibition of E-stimulated growth, but is similar in action to its basal growth inhibition of cancer cell growth. Similar to GIP-34, the 8-mer peptide when administered to MCF-7 cells, attaches to the outer bilipid layer of the plasma membrane and is thought to bind to or near a cell surface receptor in juxtaposition to a cation channel in a protein signaling cluster [
It has also been reported that the 8-mer peptide can inhibit the growth of MCF-7 cells stimulated by epidermal growth factor (EGF) as well as estradiol [
In contrast to the E-stimulated breast cancer cell growth, the inhibition of basal cancer cell growth by GIP-8 does not appear to require the presence of the human estrogen receptor and its stimulatory co-activators. Once GIP-8 binds to the cell surface and enacts K+ ion channel blockage, it appears to disrupt the signal transduction cascades that result in the cessation of cell cycle progression and subsequent mitosis (
The GIP-34 and its peptide synthetic fragments were designed and derived from a naturally-occurring fetal protein (AFP) present during human pregnancy. The encrypted GIP segment lies buried within the protein molecule until AFP encounters stress/shock environments; GIP is then exposed in the conformationally transformed fetal protein (
The hurdles encountered in the commercial developing and marketing of GIP technology products are largely involved with the cost of synthesis and manufacturing methods for peptides
From the preceding discussion, it is evident that GIP-34 and GIP-8 can inhibit cancer cell growth by different pathways, but produce similar outcomes. While each peptide may enter the tumor cell by slightly different routes, the endpoints of cell cycle arrest, and prevention of cyclin inhibitor degradation are similar. Since GIP-34 contains the GIP-8 fragment within its AA sequence, the use of GIP-34 would seem more efficient and could utilize both pathways; however, the cost of synthesis of GIP-34 is much higher than GIP-8. Both the linear and cyclic configurations of both peptides exhibit long shelf-life and the lyophilized powder can be stored in a dry state, at room temperature, in the dark for long periods of time. GIP-8, and possibly GIP-34, can be given by oral administration and could be developed into a pill-form for human medication. Both peptides are well-tolerated in animal studies, are mechanistically novel, and can be used in combination with or conjugated to chemotherapeutic drugs such as tamoxifen and doxorubicin.
A major advantage of using both peptides is that no toxic side-effects have ever been observed or reported in over 1,000 animals utilized in pre-clinical trials, even at extremely high doses [
The 34-mer peptide has the advantage of being both a cell penetrating peptide (CPP) and a channel blocker depending on peptide concentration as demonstrated by electrophysiologic studies. The CPPs are known to gain entrance into cancer cells by disrupting or disturbing the bilipid cell surface and cork-screwing itself into the plasma membranes of cells displaying an overall net negative cell surface charge as see in many cell cancer types [
Another advantage in the use of GIP-34 stems from its potential use as radiosensitizer and chemosensitizer agents as demonstrated in previous publications. One such report involved irradiated thymocytes described by Mizejewski
An unexpected advantage of using both GIP fragments was found to be enhancement of the immune response to lectins such as Con-A, and to serve as AFP antigenic epitopes for T-cell sensitization of cell-mediated immune responses. In the induction of a T-cell mediated immune response, two juxtaposed sequences on GIP-34 were demonstrated to serve as epitopes for antigen presentation of dendritic cells to T-cells to induce cytotoxic lymphocytes directed against AFP bound to hepatoma cells [
Growth Inhibitory Peptides (GIP-34, GIP-8, and a 34-mer scrambled (SCRM) peptide were evaluated for acute effects on cell membrane potential (current) and membrane resistance in cultured human breast cancer cells. MCF-7 cells were impaled
A flow diagram showing the proposed mechanism of growth inhibition of cancer cells by GIP-34 (left side) and GIP-8 (right side). Solid black-line arrows indicate pathways verified by direct evidence; the dash-line arrows represent hypothetical, proposed, or published pathways.
Historical background and development of the human alpha-fetoprotein (AFP) derived growth inhibitory peptides 34-mer (GIP-34) and 8-mer (GIP-8); relevance to biological activities (Abbreviations: FMOC = peptide synthesis method; MCF-7, T47D, MBA-MB-231 = human breast cancer cell lines; SKOVI = human ovarian cancer cell line; NYLAR = New York State mouse cell line; GWI-1 = New York State mouse mammary tumor; E2 = estradiol; C3H = inbred mouse cell line).
|1990– 1993
|Mouse, human, peptide sequence
|Immature uterus, GIP-34 synthesis, MCF-7 breast cancer cells
|Discovery of GIP-34; suppression of estrogen-stimulated uterine and cancer growth
|1994– 1995
|Human AFP-derived peptides GIP-34 and GIP-8
|FMOC GIP-34 peptide synthesis, immature mouse uterus; FMOC-synthesized GIP-8, MCF-7 cells
|Trypsin digest of GIP-34; GIP-8 and two subfragments were produced and bioassayed
|1996– 1997
|Mouse, Human AFP AFP-derived peptides, GIP-34, GIP-8
|Immature uterus, MCF-7 breast cancer cells, NYLAR mouse ascites tumor-6WI-1
|-suppression of estrogen-stimulated uterine growth; two U.S. Patents-suppression of ascites breast tumor growth; -suppression of breast cancer cell proliferation
|Human AFP-derived peptides, transformed serum HAFP
|AFP-derived GIP-34, GIP-8 and fragments
|U.S. patent issued for GIP-34, GIP-8, GIP-12, and GIP-14
|Mizejewski, Richardson
|Human AFP-derived peptides, mouse ascites fluid, MCF-7 cell focus assay
|AFP-derived GIP-34, mouse mammary tumor; linear GIP-8
|GIP-34 peptides bind to Human Estrogen Receptor; GIP-34, GIP-8-suppresses breast tumor growth
|Vakharia [
|Human AFP-derived peptide, mouse ascites; GIP-12, GIP-14, GIP-8
|AFP-derived GIP-34; GIP-8 synthesized in a cyclic form
|Peptides GIP-34 and GIP-12 binds to human estrogen receptor, GIP-14 binds estradiol and suppresses breast cancer growth
|Vakharia and, Mizejewski [
|Human AFP-derived peptide, immature mouse
|AFP-derived GIP-34 and GIP-8, mouse uterus, mammary ascites fluid and tumor cells
|-study of GIP-34 tumor, dimer/trimer oligomer activities GIP-8-suppresses uterine growth stimulated by E2
|Mizejewski [
|Human cancer cell cultures, GIP-34 and GIP-8 amino acid analogs
|Prostate cancer, breast cancer cells, MCF-7, T47D, MBA-MB-231
|Peptide GIP-34 suppresses growth of prostate and GIP-8 suppresses breast cancer cells
|Mizejewski [
|AFP-derived peptide (GIP-34), immature rat, human breast cancer xenografts, chicken, mouse pups, and pregnant linear Dams, GIP-8 fragments
|Human derived peptide, estrogen stimulated uterus, MCF-7, 6WI-1 Breast cancer cells, Chick embryo, pups and pregnant mice—GIP-34. GIP-8 and E2-toxicity and insulin birth defects
|Peptide binds cobalt and zinc; suppresses E2-supported uterine growth and basal growth of ductal and glandular breast cancer cells; GIP peptide suppresses insulin-induced birth defects; inhibits estrogen-induced uterine growth and fetotoxicity
|GIP-34, GIP-8 human cell cancer cultures and erythrocytes, mouse pups, binding and polymer assays
|HELA cells, immature mouse uterus, MCF-7 breast cancer cells, GIP-34, GIP-8
|Peptide GIP-8 optimal dose for growth suppression; pharmacophore discovered GIP-34 binding of tubulin, Congo Red and ANS fluorescent markers
|Mouse mammary tumors, various human tumors, ECM protein adhesion assays, GIP-34, GIP-8
|GWI-1 acsites mouse mammary of tumors, MCF-7 breast cancer cell, colon, ovary, prostate, melanoma,
|Peptide GIP-34 suppresses growth of 38 of 60 human tumors, mouse ascites tumors, and adhesion of cancer cells to ECM, cancer cell migration invasion, and metastasis; GIP-8 is orally active; cyclin E1 inhibited
|Chick embryo, frog tadpole, artemia brine shrimp; cancer mouse organs; human cancer, Ache enzymes, cytochromes, and enzymes
|Liver, adult and immature uterus, breast cancer cells, human platelets, MCF-7, GI-101 Breast tumors
|GIP-34 peptide inhibits cell migration, spreading, adhesion, growth processes of lower vertebrates, cell shape changes (cytoskeleton), and contact inhibition. GIP-8, found as orally active
|Human GIP-34 and GIP-8 peptides, and AFP receptor; mouse and human cancer cell cultures, tamoxifen treated cells
|MCF-7, T-47D, MDA-MB-231, MDA-MB-435, breast cancers, PC-3 prostate; liver, glial tumors, uterine hyperplasia suppressed by GIP-8
|Peptides GIP-34 and GIP-8 suppresses growth of various cancers; inhibits angiogenesis and ECM protein binding; GIP-8 does not bind to the AFP receptor
|Mizejewski [
|Human AFP full-length protein and cyclized peptides GIP-34 and GIP-8
|AFP antigenic epitopes, discovered; MCF-7, ZR75-1, MCB-MB-231 breast cancer cells
|Peptides GIP-14 and GIP-8 induce cell-mediated response and cytokine secretion. GIP-8 suppression
|Human full-length AFP derived peptides; Atlas for AFP-derived peptides
|GIP-34 peptide and other peptides, cyclized GIP-8, beta Hairpin turn as active binding site
|Functional mapping of GIP-34, GIP-12, GIP-14, and GIP-8, breast cancer xenografts
|Human cancer cell lines, tumor-bearing C3H mice, chemo-drug conjugation; Human cancer cell culture lines
|GIP-34 and GIP-8 peptides, MCF-7, ovarian SKOVI, doxorubicin; Follicular thyroid carcinoma, T47D; AFP peptides were proposed for Human therapeutic use
|Peptide targeted delivery to various cancer cells
|Mizejewski [
Global RNA microarray data: Transcripts displaying 1.0 or larger log fold (log base 2.0) decrease for genes associated with cell division and proliferation processes, ubiquitization, and cation channels obtained from Human MCF-7 breast cancer cells
|1. Calpain (LOC 441200)
|Cell cycle progression
|2. F-Box/Wd40, Domain-10 (FBXW10)
|P27 degradation pathway
|3. Serine/Threonine Kinase-33 (STK33)
|SH3 protein kinase
|4. Establishment of Cohesion-1, Homolog (ESC02)
|DNA replication
|5. Checkpoint Suppressor-1 (CHES1) (FOXN3)
|S-phase checkpoint
|6. Cyclin-E
|Regulates G-S transition
|Mediates p27 degradation
|8. Transcription Dp-1 (TFDP1)
|Binds E2F-1; G1 to S
|9. CDC20 Cell Division Homolog
|Activates ubiquitins
|10. Triple Function Domain (TRIO)
|Actin remodeling
|11. Histone-1, H4g (HIST1H4G)
|DNA repair/replication
|12. Fanconi Anemia-D2 (FRANCD2)
|DNA repair/synthesis
|1. Triparite Motif-containing-62 (TRIM62)
|Fing finger ligase
|2. SH3 Domain Protein (EVE1)
|ADAMS regulation
|3. Samd and SH3 containing Domain-1 (SASH1)
|Breast tumorigenesis
|4. SUMO1/Sentrin/SMT3 Specific Protease (SENP3)
|Lysine targeting ubiquitin
|5. Ubiquitin Specific Protease-49 (MGC20741)
|Ubiquitin enzyme
|6. Ubiquitin Ligase Protein Comples (KIAA0804)
|Protein degradation
|1. Potassium Voltage-gated Channel (KCNB2)
|Shab ion channel
|2. Transmembrane Channel Like 5 (TMC5)
|Ion transporter
|3. Potassium Voltage-gated Channel, KQT-like (KCNQ3)
|Cation signaling
|4. Calcium Channel, Voltage dependent of 2 (CACNA2D4)
|Calcium signaling
|5. Calcium/Calmodulin-dependent Kinase (CAMK2B)
|Calcium regulation
|6. Calcineurin A gamma (PPP3CC)
|Calcium phosphatase 3 protein
|7. Calcium Channel, Voltage Dependent (CACNC6)
|Calcium transport
Expression of 716 transcripts was significantly altered in MCF-7 cells after 8 days of treatment with GIP as compared to treatment with the scrambled peptide. Four hundred thirty RNAs were down regulated, while 286 RNAs were up regulated;
= real time PCR. Data provided by Kathleen Arcaro, University of Massachusetts, Amherst, MA [
The author expresses his appreciation to Tracy Godfrey for her commitment and time expenditure in the typing and processing of the manuscript text, references, and tables of this paper. The author also extends his gratitude to Ms. Rachel Moseley and Christopher Harkins for the computer graphics artwork and illustrations presented here. Gratitude is extended to the Albany Medical College Research team for confirming and extending the author's work on GIP-8 (AFPep). Acknowledgment is also made to Serometrics, LLC, Syracuse, NY, for partial funding of the GIP research awarded to Kathleen Arcaro, University of Massachusetts, Amherst, MA, and L. Michael King, SUNY Albany, East Greenbush, NY.


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Tell your own festive stories with this new create-a-story pack from StoryWorld.Create holiday stories with Christmas Tales. This box contains twenty-eight cards that suggest all kinds of characters, places, and objects that you can use to make up your own stories. Pick a handful of cards and use their pictures, descriptions, and questions as inspiration. Discover more ways to use the cards and read sample stories in The Storytelling Book that accompanies this set.


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fruiterernoun [ C ]uk /ˈfruː.tər.ər/ us /ˈfruː.t̬ɚ.ɚ/ mainly UK old-fashioned
Thesaurus: synonyms and related words
Examples from literature
- It's too late now to find any of the first-class fruiterers open.
- Only a fruiterer's stall at the corner made a violent blaze of light and colour.
- She went to the fruiterers, and ordered grapes and peaches.
- They sell all the ripe ones to the fruiterers.
- When she comes get her to tell you the story about the fruiterer who lives opposite her.


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Non Surgical Nose Job Q&A
Steroid + Non Surgical Nose Job
I want thinner nostrils without surgery. Any suggestions? (photos)
I had rhinoplasty for 10 months ago. And now I am still unhappy with my nostrils. They are still wide as before. I want them as shown in the photos, a... READ MORE
Will Steriods Help in Treatment of Nasal Callus?
I was hit on my nose 18 months ago strong enough 2 cause a wound which needed sutures yet my nose wasnt broken but i have a bump which my doctor told... READ MORE
Is It Safe to Inject Steroid to Make the Nose Look Better Without Surgery?
My doctor told me that i need to inject steroid in my nose to make it look better after my rhinoplasty I`m not sure if it is realy safe ? READ MORE
Can anyone get steroid injection to reduce the fat in the nose and make it slimmer?
One doctor claimed that steroid injection could reduce the fat in the nose and make it slimmer. . so its not only after rhinoplasty treatment , and it... READ MORE


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Traveling with a Heavy Stainless Steel Back-Plate can add unnecessary weight to your baggage limit, costing you additional travel fees. Lighten the load when you travel with your Scubapro X-Tek Form Harness Assembly. This X-Tek Soft Travel Back-Plate is easy to install on your Harness and will allow easy packing and lighter weight for the traveling Technical Diver.
Soft Back-Plate is made from Durable Nylon Fabric and Webbing with Taped and Sewn Edges for added Strength and Durability. Back-Plate is equipped with Grommets for Safe and Secure Mounting and comes with 2 Scubapro Super Chinch Tank Cam Bands. Cam Bands are constructed from Strong 2" (5.1 cm) Nylon Webbing with Super Chinch Corrosion Resistant Stainless Steel Buckles.
This product has a limited warranty of 12 months.