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Fluid Dynamics
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Chaotic Systems: Theory and Applications, Selected Papers from the 2nd Chaotic Modeling and Simulation International Conference (CHAOS2009)RentList Price:$144.00
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Bad things tend to happen when Two and a Half Men star Charlie Sheen is not working. This morning, Sheen was taken to the hospital with severe abdominal pain, the actor's publicist Stan Rosenfield confirmed. Men is on hiatus this week, so Sheen is not due back to work until Tuesday. It is not clear if his illness will affect the show's production schedule. Earlier this month, Sheen briefly saw a doctor for what was described as an ear infection. This is the fourth incident involving Sheen that has happened while he is off the show, following his Christmas 2009 arrest in Colorado, his November New York hotel room episode that resulted in a trip to the hospital and his recent Las Vegas weekend escapade. Today's hospitalization comes hours after Sheen's Men co-star Jon Cryer joked on Conan last night that he checks TMZ every morning to see if he should go to work. (Today's Sheen hospital visit story was broken by the gossip site, which provides salacious details about heavy partying that allegedly preceded it.) And at TCA, CBS entertainment president Nina Tassler acknowledged the network brass are concerned on a "on a personal level, but (Sheen) has his job, he does it well, and the show is a hit." As we previously reported, CBS and Men producer Warner Bros. TV have been looking for ways to get Sheen to seek professional help for his addiction, including shutting down production on the show, but Sheen has refused to do so and has retained top litigator Marty Singer, threatening to sue the studio if they stop production.
Charlie Sheen Rushed To The Hospital, 'Men' Production Not Affected – For Now
75 Comments
The show won't be a hit when he's dead.
If you want the cash cow to keep producing milk, you have to take action to care for it's health.
Great comment. I think the show should write an episode with Charlie drinking and drugging himself to death and then make himself watch (as a ghost) his children and family at his funeral, and make it a very long funeral with lots of takes.
Huh? This isn't Blossom.
That sounds like a 'bruised' liver. I honestly hope it's not so bad. Sad. I really hope it's something minor. Get well dude!
Peter Roth and Nina Tassler, if they had were truly Charlie's friends and truly concerned for his welfare should have told him he was off the the show if he didn't go to rehab for six months…
Instead they will be the first to speak at his funeral. Crying and wailing and saying what a shock this all is.
Do they realize how transparent they are?
Since he was "smart" enough to drink himself into oblivion on hiatus, CBS will yet again make excuses, cover up for him, and look the other way. While his costars and celeb ass kissers will wish him well ignoring the obvious. He's on his way to being a celeb listed at the In Memorium part of the next major awards show. At what point will someone show him tough love? At what point will he lose his job? Lohan lost her career. Sheen however seems to just get away with anything. It's both sad and sexist the way no one is calling him on his sh*t nor axing his arse from the show.
It's not sexist. Lohan lost her career because she stopped rendering services. As CBS and WBTV have made clear, Sheen is still performing. Believe me, the minute he can't make it through a taping, they'll go after him for breach.
When was Lohan unable to render services? I think the point is that Sheen is on a hit Tv show, while she is not. Remember I Know Who Killed Me?
Lohan was unable to render services on the Lovelace picture because she was in court, jail and rehab and the pic kept postponing.
When Lilo was booked on a film she would miss days or show up late. Charlie is never dumb enough to screw up a production day.
That movie is a joke and has problems even getting financing let alone distribution!!
When Lilo was booked on a film she would miss days or show up late. Charlie is never dumb enough to screw up a production day.
Comment by Nellie — Thursday January 27, 2011 @ 3:43pm PST
That was 4 years ago: she made 2 movies after that and the producers and directors were had no problems with her. Not to mention the fact that she made crappy movies.
As for Lilo, it isn't just that she isn't on a hit show or had a hit movie lately — when she did that movie with Jane Fonda (which I can't recall the name of right now), she got a warning letter from the producers for her flaky attendance. Even a recent photo shoot for her own line of clothing, she was reportedly 12 hours or so late. This affects insurability. Producers can't get insurance, whereas Charlie still keeps his work commitments.
Yep and Marty Singer will yell about legalities in order to let Charlie kill himself. pig
A new episode aired last week and Charlie looked really haggard. He looked really thin and tired (more than usual). Sad to think that people around him say it's just "Charlie being Charlie"…..
He looked so thin. I thought it was Christian Bale for a minute.
The guy's got a playboy mentality, unlike his papa. Playboys usually get into trouble and he's no exception.
Warren Beatty was a playboy. Robert Evans was a playboy. Charlie is proving to be nothing more than a coke and porn addict!
er, I believe you meant coke and porn star addict… with a license to print MONEY!!! pump his stomach, get him hydrated and get him back on the set so the presses can keep rolling. come on people, Leslie has stockholders to appease.
He's addicted to both. Look at the records from his divorce with Richards.
Severe abdominal pain is code for explosive diarrhea. Just come out and say it. No need to protect this ass.
Shut up Ho!
Given his alcohol issues is 'severe abdominal pain' a major symptom for liver issues.
He sure is prone to a lot of "illnesses." Take some Pepto and "Git back to work!"
CBS won't be satisfied until he's dead.
Ha-ha, Charlie my boy, you keep em laughing! Lay off Charlie folks. He's got a strong constitution, he's a young man sowing his wild oats and most of all, HE IS A SURVIVOR! So let Charlie be charlie. He's a man's man, you chicks wouldn't understand. He's the pride of Malibu even though he doesn't actually live in the 'bu he still parties hardy here and the merchants and restauant owners and cocktail servers love his big tips, his nice smile and his friendly way!
Malibu Rocks, out.
Young man sowing wild oats?! He's 45 and has two kids. He's making himself look like a freaking idiot. And like you said, the only people who think he's a hoot and so much fun are people who are making money off of him. What really counts in a person's life is how they treat other people and whether or not they value their life. He clearly doesn't value his life and must not give much of a sh*t about his daughters. Yeah, that's a real class act right there. A guy trying to act half his age, doing illegal drugs, and f*cking so many porn stars he's probably got a half a dozen STDs. What a life, what fun! NOT.
Uh, he has four kids, not two, but your other points remain valid.
Charlie has five kids, one who is 25 from a previous relationship back in the day.
Oh crap I forgot. I was thinking he just had the two with Denise. Well then that's even worse, just adds on to the number of people he's throwing aside in exchange for coke and porn. Classy guy, classy guy.
He actually has 5 kids, including the daughter that just got married.
But, I can understand not remembering. Its a sure thing that Charlie doesn't.
UHH actually he has 5 kids not 4
I bleed for him, I really —–.
I'm sure he has a pleasant personality and a lot of good qualities, but "chicks" understand all too well physically abusive, alcohol, drug and porn addicted guys — it has nothing to do with being a man. In fact, since it is the opposite of honorable and dignified, it seems to be taking him in the opposite direction of what would be described as manly.
When you're in showbiz & your successful, a 45 year old is allowed to behave like a 21 year old…until the actor is no longer a success…and then "It's Scott Baio time". Charlie, you better have a good reality TV agent!
he wont need to do reality, guys got enough money even with doing a constant train of cocaine and hookers…
The guy is a douche. Simple as that.
You know the only thought that came to me when I read this was to read up on the difference between affect and effect. I always get them confused.
Well read up assistant.. The effect of your confusion affects my head.
Charlie just seems as if he doesn't want help. He doesn't seem to think he has a problem. Never ashamed. He's older and still acts the same way he acted in his youth.
Is it possible to… swallow an entire hooker?
Bwahahahahahaha! Thanks, that had me rollin'. This whole situation is so NOT funny but THAT was.
What's the over/under on a Leno writer reading this and sticking it in the monologue?
Is it possible to swallow an entire hooker? Well, given his alleged propensity to overindulge — if anyone could I'm sure Charlie would.
This has kind of reached the Anna Nicole/Michael Jackson tipping point where you stop asking if or how he's going to die but you just start counting the days.
Am with you on that. I thought about Anna Nicole as soon as i read the headline.
The real bad news here is production on 'Two And A Half Men' will NOT be affected.
It says that his ABDOMINAL PAINS triggered the 911 call. It's obvious that Charlie thought to himself "well if c.o.c.aine was used for toothache back in the 1800's, a lil c.o.c.aine will help my abdominal pains" so he went ahead and dunked his head into a pile: http://bit .ly/etYpXq
Boy in Police Station: What's your name?
Jeannie: It's Jean, but most guys call me Shauna.
Boy in Police Station: Okay, Jean
Boy in Police Station: There's someone you should talk to.
Jeannie: If you say Ferris Bueller, you lose a testicle.
Boy in Police Station: Oh, you know him?
How do you get on his list of partiers or is it always just Charlie & a bevy of porn stars? Am I jealous? You bet!
Please fire Mr. Sheen he's an embarrassment and I no longer want him portraying me on such a fine show. I had a good reputation before CBS stole my life story and cast Mr. Sheen as me. I was never paid for my life story rights and to this day I don't understand why. They told my lawyer they thought I was just a fictional character and therefore they don't owe me any money. But having to watch Mr. Sheen week in and week out has now become too much for my delicate sensibility to take. I simply can't watch the show any more. Please send Mr. Sheen to Celebrity Rehab or if that can't be arranged as a reality show just send him to prison where he belongs. He got away with attempted murder in Aspen then again in New York. Why does he always avoid being sent to prison for his terrible crimes against women? You never see me getting in trouble like that.
Replace Charlie with Thomas 'tomas' Lennon.
Charlie's probably suffering from "mercury poisoning."
Sad news. Once again CBS will pretend everything is OK. Sheen's publicist will let loose some BS story about what happened. Probably will be "food poisoning" or the "flu". CBS will probably give Sheen another raise. At least his latest porn star "date" Kacey is kind of hot in the "jailbait" look category.
It could be appendicitis.
Hey folks this is the industry that eats its young. Why would it not eat it's middle aged?


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Fewer people died on Portage County roadways in 2012 than the year before, according to Ohio Highway Patrol statistics.
Portage County saw 13 traffic-related fatalities in 2012. That's a decrease from 2011, when a total of 17 people died in vehicle and pedestrian crashes within Portage County's borders and on the Ohio Turnpike.
The highway patrol does not count deaths on the toll road toward Portage County's tally in final statistics, meaning that 15 people died on state, county and city streets and roads in Portage County in 2011, excluding the Turnpike.
Impaired driving -- drivers under the influence of alcohol, drugs or a combination of both -- and unsafe speed were the leading causes of traffic deaths in 2012. Lynette Blasiman, director of Portage County Safe Communities, said the leading causes of crashes in 2011 also were impairment due to alcohol or drug use and speed. Though there were fewer fatal crashes in 2012, the number of crashes blamed on impaired driving and speed increased, she said.
"Of the 13 deaths, four were alcohol/drug-related and five involved unsafe speed with a correlation between the two," said Lt. Nakia Hendrix, the commander of the highway patrol's Ravenna post. "Although impairment and unsafe speed get the most media attention, it should not go unsaid that driver inattention is also a major contributing factor in many fatalities."
Hendrix, who has since left the Ravenna post for a new assignment, said driver inattention includes failure to yield, failure to control, lane violations and other habits that take a driver's attention off the road.
"Staying alert as a driver and avoiding complacency behind the wheel can help to make for safer travels," he said.
The Portage County Fatal Review Board, made up of local law enforcement officials and members of the Portage County Safe Communities Coalition, meets quarterly to review fatal crashes in Portage County. The board recently met to discuss trends in crashes that occurred from October through December 2012, according to Blasiman.
Other data of note in the 2012 report included:
n For the second year in a row, the deadliest day of the week was Tuesday. Six of the 13 fatal crashes occurred on Tuesdays in 2012. Only the months of March and December passed without a single fatality.
n Nine fatal crashes occurred between 12:01 p.m. and 11:59 p.m. Only four were from the hours of midnight to noon.
n Ten men and three women were among the fatalities.
Portage County Prosecutor Victor Vigluicci said the education and enforcement efforts utilized to reduce fatal crashes are to be praised.
However, "until there are zero traffic deaths, our work is not done," he said.
Follow Dave O'Brien on Twitter at @RCCrimeWatch
Contact this reporter at 330-298-1128 or email@example.com
**"For the second year in a row, the deadliest day of the week was Tuesday. Six of the 13 fatal crashes occurred on Tuesdays in 2012"** To all the gun control folks, Tuesday is killing our people. I say we need to either ban Tuesday, or restrict the hours you can drive in Portage County on Tuesday. Maybe even ban cars/trucks. Limit the size of vehicles, only bicycles. Everyone that wants to drive on Tuesday has to go through a mental health background check to make sure you can pay attention and that you have walking around sense. I suggest warning signs be put up at the Portage County Borders, warning driver that they may not make it out of the county alive on Tuesday. Come on Democrates/Republicans, where is the outrage? We need legislation!! "Tuesday is Killing Our People"


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Twenty-four thousand Allied paratroopers had already hurtled into the dank gloom all over Normandy.
I called him from a dank hotel room in Guatemala and broke it off.
They sat stock-still on the hardwood benches of the dank, makeshift cinema in Monrovia.
But why do the outdoor scenes look as dank and drab as the gas-lit, sepia-toned interiors?
She suffered no more beatings—just solitary confinement in an underground cell always dark and dank and cockroach-infested.
From her gleaming neck down to the ground was dank, shapeless form.
Between this dank forest and the river-banks lie the cultivated fields.
The dank, decaying vegetation, the dimness, the very airlessness of the sweltering valley—all this is not merely heat.
She smiled, put back her hand and brushed the dank hair from his moist brow.
Laden with its salt scent, the dank vapor had enveloped an old house on the "brew" behind the town.
c.1400, earlier as a verb (early 14c.), now obsolete, meaning "to moisten," used of mists, dews, etc. Perhaps from Scandinavian (cf. Swedish dank "moist place," dänka "to moisten") or German (cf. Middle High German damph, Dutch damp "vapor"). Now largely superseded by damp (adj.). Related: Dankness.


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It is estimated that 400 fatal accidents occur due to improper tire maintenance. Here are some simple tests you can perform yourself to assure that the tires you currently have will get you to where you need to go safely.
Observe the Tread Pattern
All tires carry what are referred to as the "tread wear bars" which are small ridges that form on the surface of the tires. One of the common indicators that your tires need to be replaced is when your the tread wear bars begin to even out with the tire surface.
The Penny Test
Take a penny, place it upside down so that Lincoln is facing you and place it on the ridge.
- -If you can see the Lincoln's head, tires should be replaced immediately.
- -If you can partially see the lush full headed set of hair of honest Abe, you should start thinking about replacing the tires.
- -If you can see Lincoln's forehead, keep driving. You're all good to go.
Tire Tread Depth Gauge
Tire tread depth gauge is a relatively cheap measuring device available in most auto supply store. You can use the gauge to measure the treat to get a more accurate reading.


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This fabulous treatment is a physical, manual exfoliation of the skin. It is often used in preparation for chemical peels or facials. Dermablading removes the outer most layer of skin as well as vellous hair (peach fuzz) leaving behind smooth and vibrant skin. The procedure is safely performed with a sterile blade held at a 45 degree angle and stroked along the skin. This is a very safe procedure when performed by a trained professional. Blading removes about 3-4 weeks worth of dead skin cells and hair, Making this a perfect procedure for dull skin, fine lines, and fuzzy faces. The vellous hair does not grow back darker or thicker this is physiologically impossible. Deeper product penetration is also an added benefit. All skin types can benefit from blading however it's not recommended for clients with active acne. Blading is performed on the face only. I do not blade the nose, eye lids, neck or chest.
MicroPeel… $100.00
A three step process that includes dermablading followed by a lactic acid chemical peel and a mask appropriate to skin type. Also includes extractions.
This is for exfoliation, dull skin,fine lines, uneven skin tone, smoothing texture of the skin, deeper at home product penetration.
MicroPeel Plus……. $110.00
A three step process that includes dermablading followed by a higher level glycolic/salisilic peel combo followed by a soothing cooling mask. Also includes extractions.
This is for hyper pigmentation, acne scarring, fine lines, uneven skin tone, exfoliation, smoothing texture of the skin, deeper at home product penetration. Peeling may occur 2-3 days after treatment.
Add Dermablading only to a facial…… $35.00
Dermablading only…… $65.00


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Single-blind study
A single-blind study is just like a double-blind study , except that the researchers know which group is receiving which treatment. This type of study is a bit questionable, as it allows for bias on the part of the doctors conducting the study. (Doctors can subtly convey confidence or a lack of it if they know who is receiving real treatment and who is not; they can also unconsciously bias their evaluation of the results.)
Please note, not all procedures included in this resource library are available at Henry Ford Allegiance Health or performed by Henry Ford Allegiance Health physicians.
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Column: Prevent irreparable damage to pristine valley
The discussion regarding the frac sand issue facing our area has its roots firmly embedded in our insatiable appetite for energy.
The development of energy has both an upside and a downside. On the upside, it enables economies to grow, businesses to flourish and workers and their families to thrive. The downside is that the major sources of energy products are the same energy products that are spewing thousands of tons of carbon into our atmosphere every year.
The science is "in" on global climate change: 99 percent of all creditable scientists agree that climate change is a result of our dependence on fossil fuels to create the lifestyles that we have become accustomed to. The burning of coal, fuel oil and natural gas to create electricity, coupled with the internal combustion engine powering our transportation system, is responsible for almost all of the carbon loaded into our atmosphere.
This science is only disputed by those who have a vested financial interest in producing polluting, earth choking energy products or they are simply ill-informed.
In regards to our area, sand mining facilities have operated on both sides of the Mississippi for many years. In general, companies that are engaged in this business are smaller family-owned businesses. These family businesses have operated in a safe and environmentally effective manner, created jobs and have been active valued members of our communities. These companies have proven that under the right circumstances, sand can be safely mined.
But, make no mistake; these conglomerations proposing to mine sand in Goodhue County and other parts of southeastern Minnesota, as well as several counties in Wisconsin, are not small, family-run businesses. No, simply put, their method of operation closely resembles the way big oil has bullied and bought their way to profitability. And when big oil wants something, big oil gets it.
Right now big oil wants our sand so that they can create even more environmental nightmares by mixing it with chemicals and pumping it under high pressure into the ground and harvesting whatever might pop out. We need to make sure that when they get their way, it is done safely and only in those areas that will not do irreparable damage to our pristine valley.
Big oil and their minions have influenced the political process by splashing around very large contributions to both major political parties and to individual candidates. For this amount of money, they expect results. They also bully legislators and local officials by claiming that the price at the pump will skyrocket if they are not given permission to rape our planet. They claim that any responsible environmental reform would result it hundreds of thousands of workers being unemployed and a collapse of our economy.
Big oil did not invent these schemes of "splash the cash" or the "sky is falling" element of fear to further their cause, but, between them and the industrial military complex, they have perfected the practices.
We have clearly seen this same type of behavior by the frac sand companies. They have promised plentiful employment, they claim to be environmental stewards and their ever-too-close cozy relationships with elected and non-elected government officials are the Washington, D.C./big oil method of doing business.
Like I said, big oil is going to get what they want, but we need to ensure that by doing so the legacy that we leave our grandkids is one that we will be proud of.
Steve Murphy of St. Paul and formerly of Red Wing represented this area in the Minnesota Senate for 18 years. He periodically writes a column.


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Dance Unlimited wins two state dance titles
Staff Report - May 11, 2006
On Sunday, April 9 the Louisiana Association of Dance Masters crowned their new title winners. For the fifth time in six years, Duanne Cazalot, Samantha Sidwell and Angie Lehrmann were honored to be the teachers of the Louisiana state title winners.
Dance Unlimited will send a total of three representatives to The Dance Masters of America National Competition in Las Vegas.
Read More Stories at HeraldGuide.com!
|heraldguide.com is a supplement to St. Charles Herald Guide.
Copyright © 2001 - 2017 St. Charles Herald Guide, Inc. All rights reserved.
Please contact our WebMaster if you experience problems with the website.


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Tracy Bunge
A Jayhawk from 1983-1986, Bunge completed her softball collegiate playing career as one of the most decorated athletes ever to wear the Crimson and Blue. A 1986 All-American, the first for softball at KU, and a 1987 inductee to the Kansas Athletics Hall of Fame, Bunge dominated both on the mound and at the plate in her four seasons at KU. During her four-year tenure as a Jayhawk athlete, Bunge led KU to three 30-win seasons and three Top 10 national rankings. She ended her decorated career by leading KU to a 39-8 record and a No. 5 final national ranking in 1986. As a freshman in 1983, Bunge compiled a 23-8 record with an amazing 0.63 ERA and 185 strikeouts in 234 innings pitched. She also finished second on the team with a .258 batting average and led the 33-9 Jayhawks with 15 RBI. A year later, Bunge hit .341 with 10 RBI and finished with a 0.73 ERA in 21 appearances as a pitcher. Bunge continued to impress as a junior when she went 24-11 on the mound with a 0.82 ERA and hit .358 with 24 RBI. In 1985, Bunge was chosen to be a member of the Atheletes in Action European Tour team and hurled 11 victories, including three no-hitters and a perfect game. In addition, she was named Academic All-Big Eight in 1985 and 1986. As a senior, Bunge rounded out her Kansas playing career by setting the KU single-season mark with a 0.55 ERA while hurling 15 shutouts, good for fifth all-time. She currently holds the career record for lowest ERA (0.68). Bunge was hired as head coach of the Jayhawk softball program in 1997 and is 282-245-1 in nine seasons here.
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- Watch: Nitish Kumar takes oath as Bihar CM
- Watch - Bike riders swept away with flood water in West Bengal
- Cabinet reshuffle soon: JD(U) likely to get ministerial berths
- Bihar Assembly trust vote: Some Congress MLAs may back Nitish Kumar
- PM Modi hails Nitish for moving out of Bihar 'Mahagathbandhan'
- It's for Nitish Kumar to decide on allying with BJP: Ravi Shankar Prasad
- Zee News remains number 1 Hindi channel for 29th week
- Watch : 2-storey building collapses in Ahmedabad
- JD(U) chief said will die but not join BJP: Lalu Yadav
- Exclusive: Sudhir Chaudhary in conversation with Indian women's cricket team
- Dr Subhash Chandra raises cable licensing issue in Parliament
- Gujarat floods: Death toll rises to 123
- Watch: Drums being used to warn people about floods in Gujarat
- Watch - The ten biggest international news of the day
- Watch: Akshay Kumar hails Indian Women's Cricket Team
- Nitish Kumar's swearing-in ceremony: As it happened
- WATCH: Virat Kohli, Ravi Shastri burst into laughter with Ravindra Jadeja's dressing room act
- Pakistan cricketers set to get richer as PCB receives Rs 230 million from ICC as Champions Trophy prize money
- Bharti Singh to quit 'The Kapil Sharma Show' - Here's why
- Rift in JD(U) over aligning with BJP: Sharad Yadav not kept in loop by Nitish, say senior leaders
- 'Not a sign of healthy democracy': Mayawati on Nitish Kumar's JD(U) alliance with BJP
- India's Tour of Sri Lanka 2017: 1st Test, Day 2 — As it happened...
- Panama Papers case: Pakistan's Supreme Court disqualifies PM Nawaz Sharif
- Kapil Sharma Show: Sumona Chakravarti will NEVER work with Krushna Abhishek—Here's why
- Will Nitish Kumar's 'ghar wapsi' in NDA help BJP in Rajya Sabha? Here are the numbers
- French lawmakers approve law banning nepotism
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text:
|7400:478 Senior Portfolio Review – delete corequisite and change prerequisite
|Submitting Dean
|James M. Lynn
|Submitting College
|College of Health Sciences and Human Services Jim Lynn x6519
|Departments Generating the Proposal
|Objection Deadline
|February 02, 2010
|Proposal Status
|Final Approval Granted
|Proposal Last Updated
|February 05, 2010 by Karen Greene
|Effective Date
|Fall 2010
|Brief Summary of Proposal
|Delete the corequisites: 7400:434 Senior Design Studio III, 7400:459 Senior Design Studio IV. Change prerequisite from permission to: permission of instructor.
|Type of Proposal
|Course changes only
|Graduate School Endorsement Status
|Not required
|Graduate School Endorsement Updated
|November 18, 2009 by GS Heather Blake
|Institutional Research Status
|IR Status Updated
|November 20, 2009 by IR Anu Mahapatra
|Library Status
|Library Status Updated
|November 18, 2009 by UL Joe Larose
|Distance Learning Review Committee Status
|Not required
|DLRC Status Updated
|General Education Advisory Committee Status
|Not required
|GEAC Status Updated
|November 24, 2009 by Karen Greene
|Resource Requirements
|No additional resources
|Resource Requirements Updated
|November 18, 2009 by FA dean's ofc Gerry McElliott
CPS Menu


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A Place to Rest
Decaying Mind
An October Evening
Sector Four
Let The Stars Embrace You
One Moment Live
Live On Earth (Live at Awakenings)
Moments in Sound
Subliminal Dreams Vol 1
This Desolate Place
Darkness Within
Influenced by the dark space ambient journeys of Oophoi and Steve Roach. The music is created with a range of hardware and software synthesizers and samplers, along with various effects and field recordings.
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Sean Penn, Bruce Willis, Stanley Tucci, John Turturro, and Kristen Stewart will all take starring part in Barry Levinson's "What Just Happened?."
With the coming of more Hollywood's household names, sure "What Just Happened?" is going to be an all-star flick worth waiting for.
Following the inclusion of Robert De Niro into the cast, another five well-known stars have smoothly been added to the list: Sean Penn, Bruce Willis, Stanley Tucci, John Turturro, and Kristen Stewart. All will come together under the direction of Barry Levinson as they enter production scheduled to begin March 22 this year.
Written by Art Linson whose memoir the flick is based on, "Happened" sees De Niro play Ben, a film producer who tries to maintain his dignity as his soul is slowly destroyed by the machinations of Hollywood and the breakup of his second marriage. Todd Wagner and Mark Cuban's 2929 Productions are funding the comedy with Linson, De Niro, and Jane Rosenthal seating as producers.


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Age 42-Had Eyelids,Midface and Necklift Procedure,
I notice that I am going through alot of different stages during my five weeks recovery time...Good days and bad days.. Now into the 5th week I am getting nervous about my results.
Is it common to have a ripple effect (or unsmooth skin)after one month and will it smooth out.
I still have on a scale 1-10 swelling around the eyes on a scale of 7.
The neck has healed and looks great..
Ripple Effect-Beverley Hills, Ca
Age 42-Had Eyelids,Midface and Necklift...
Age 42-Had Eyelids,Midface and Necklift Procedure,
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The latest World Economic Forum rankings of global business competitiveness are out, and while Canada slid a notch overall, the results show enough clear signs of improvement to encourage Canadian policy-makers to continue – even double down on – initiatives aimed at bolstering innovation.
The headline result was discouraging. Canada now ranks 15th out of 144 countries for its business competitiveness, down from 14th last year and a high of ninth in 2009. The WEF's annual review assesses 112 factors related to a country's competitiveness, including financial-market efficiency, labour-market qualifications, technological readiness, innovation and business sophistication.
Canada's slide has mostly been a story of other countries' greater success, as they pass us in key measures having to do with productivity and technology. But there are signs of success within the data, especially in areas critical to future growth.
While small companies have long complained about the lack of available financing from loans or venture capital investment, Canada ranked fifth globally in 2014 for availability of financial services, up from ninth last year. It sat in 17th place in venture-capital availability, an improvement from 23rd place a year ago, thanks to a blossoming of new venture capital programs in the past two years. There have also been successes in transitioning to an economy based on advanced processes rather than raw natural resources, and in increasing the sophistication of production processes.
There is still much that needs to be done. Canada's infrastructure scores – the quality of our roads, railroads and ports – are falling. We still lag in the critical categories related to technology and innovation, with company spending on research and development trailing at just 27th place overall, although up from 29th place last year. Canada ranks just 26th for its capacity to innovate.
These areas defy simple fixes, but other countries have proved it is possible for policy-makers to spur huge improvements in innovation with support from business leaders. Canada has had its own policy successes in key areas, and more is possible. Our comparative global competitiveness underpins Canada's strong economy. It cannot be allowed to continue slowly eroding with each passing year.Report Typo/Error
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This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
Interleukin 1β (IL-1β) and tumor necrosis factor α (TNF-α) are key cytokines that drive the production of inflammatory mediators and matrix-degrading enzymes in osteoarthritis (OA). These proinflammatory cytokines bind to their respective cell surface receptors and activate inflammatory signaling pathways culminating with the activation of nuclear factor κB (NF-κB), a transcription factor that can be triggered by a host of stress-related stimuli including, excessive mechanical stress and ECM degradation products. Once activated, NF-κB regulates the expression of many cytokines, chemokines, adhesion molecules, inflammatory mediators, and several matrix-degrading enzymes. Therefore, proinflammatory cytokines, their cell surface receptors, NF-κB and downstream signaling pathways are therapeutic targets in OA. This paper critically reviews the recent literature and outlines the potential prophylactic properties of plant-derived phytochemicals such as curcumin and resveratrol for targeting NF-κB signaling and inflammation in OA to determine whether these phytochemicals can be used as functional foods.
For the past 160 years human life expectancy has consistently increased by a quarter of a year every year [
According to the World Health Organization (WHO) [
The United Nations, the WHO and 37 other countries have proclaimed the years 2000–2010 as the Bone and Joint Decade [
Musculoskeletal diseases are one of the major causes of disability around the world and have been a significant reason for the development of the Bone and Joint Decade [
OA is one of the most common types of arthritis [
The major consequence of all forms of arthritis is joint dysfunction, disability, chronic pain, and significant morbidity. Aside from analgesics, there are currently no effective pharmacotherapies capable of restoring the structure and function of damaged synovial tissues in any form of arthritis. Consequently, there is an acute need for novel drugs and new therapies. In the following section we provide a brief overview of cartilage structure and function before discussing the molecular and cellular events that occur in a typical synovial joint in OA.
Cartilage is a flexible and mechanically compliant connective tissue found at the end of long bones in articulating joints and in the intervertebral disc. It is sub-classified into three different types: elastic cartilage, hyaline cartilage and fibrocartilage, which differ in the relative amounts of its three principal components, namely collagen fibers, ground substance (proteoglycans) and elastin fibers. Articular or hyaline cartilage is a load-bearing tissue with unique biological characteristics (
Its biochemical properties depend on the structural design of the tissue, the molecular composition of the ECM (
Chondrocytes are the only cells found within the cartilage ECM. Cartilage is avascular, alymphatic and aneural. Nutrition is derived from synovial fluid (and for the deep zone by subchondral bone vessels). Chondrocytes are architects of cartilage [
ECM proteins in cartilage are of great significance for the regulation of the cell behavior, proliferation, differentiation and morphogenesis [
Throughout life, cartilage is continually remodeled as chondrocytes replace matrix macromolecules lost through degradation. Evidence indicates that ECM turnover depends on the ability of chondrocytes to detect alterations in the macromolecular composition and organization of the matrix, such as the presence of degraded macromolecules, and to respond by synthesizing appropriate types and amounts of new ECM components. It is known that mechanical loading of cartilage creates mechanical, electrical, and physicochemical signals that help to direct the synthesizing and degrading activity of chondrocytes [
Although articular cartilage can tolerate a tremendous amount of intensive and repetitive physical stress, it manifests a striking inability to heal even the most minor injury [
OA (also known as osteoarthrosis or degenerative joint disease) is one of the most prevalent and chronic diseases affecting the elderly [
OA can affect any synovial joint but it primarily affects large load-bearing joints such as the hip and knee. The disease is essentially one acquired from daily wear and tear of the joint. Its most prominent feature is the progressive destruction of articular cartilage [
It is now generally accepted that OA must be viewed not only as the final common pathway for aging and injuries of the joint, but also as an active and inflammatory joint disease. As medical advances lengthen average life expectancy, OA will become an even larger public health problem—not only because it is a manifestation of aging but because it usually takes many years to reach clinical relevance. OA is already one of the ten most disabling diseases in industrialized countries. It is one of the most prevalent and chronic diseases affecting the elderly [
The symptoms and signs characteristic of OA in the most frequently affected joints are heat, swelling, pain, stiffness and limited mobility. OA is often a progressive and disabling disease, which occurs in the setting of a variety of risk factors, such as advancing age, obesity, and trauma, that conspire to incite a cascade of pathophysiological events within joint tissues [
OA, is an important cause of disability-adjusted-life years in both the developed and developing world [
Cytokines are signaling molecules and major mediators of inflammatory responses. They are small proteins and signaling molecules produced by a variety of different cell types. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis. They play essential an indispensable roles in cell signaling and communication and possess potent immunomodulatory properties. They are also involved in a plethora of pathophysiological processes including viral infections, autoimmune diseases, arthritis and cancer. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. They have been classed as lymphokines, interleukins, and chemokines, based on their functions. The term "interleukin" was initially used by researchers for those cytokines whose presumed targets are principally leukocytes. The term "chemokine" refers to a specific class of cytokines that mediates chemo-attraction (chemotaxis) between cells. In many publications cytokines are listed along with hematopoietic growth factors, interferons, lymphokines, monokines, chemokines, and other cytokines [
It is now generally accepted that proinflammatory cytokines are pleiotropic contributors to synovial joint pathology in OA and RA. In the following sections we discuss the principal cytokines involved in the pathogenesis of OA and its progression. Many studies have demonstrated the involvement of cytokines in the pathogenesis of OA (
There are also other proinflammatory cytokines produced by the synovium and involved in the OA disease process to a lesser extent. The effects of the proinflammatory cytokines on cartilage are shown in
The activation of NF-κB (nuclear factor-κB) transduction pathway has been linked with a variety of inflammatory diseases, including cancer, atherosclerosis, myocardial infarction, diabetes, allergy, asthma, arthritis, Crohn's disease, multiple sclerosis, Alzheimer's disease, osteoporosis, psoriasis, septic shock, and AIDS [
Recent research has shown that the pathway that activates NF-κB can be interrupted or functionally modulated by naturally occurring phytochemicals derived from spices such as curcumin, capsaicin, eugenol, gingerol, anethol, ursolic acid, diallyl sulfide,
Current treatments for OA and gut are associated with unwanted side effects and are expensive. Natural products do not have such disadvantages, offer alternative treatment options for OA [
The first preliminary study on the anti-rheumatic activity of curcumin was published in 1980. Unfortunately, this study was fundamentally flawed because of the lack of appropriate controls [
In chondrocytes curcumin was shown to suppress oncostatin M (OSM) stimulated STAT1 phosphorylation, DNA-binding activity of STAT1, and c-Jun
Work from our laboratories has demonstrated some of the protective and anti-inflammatory effects of curcumin using biochemical and morphological techniques. To test the hypothesis that curcumin protects chondrocytes from morphological alterations induced by IL-1β, we investigated its
Curcumin appears to exert its anti-inflammatory effects in a "concentration-dependent" or "dose-dependent" manner. Studies on RA-derived synovial fibroblasts have shown that curcumin dose-dependently abrogates the effect of IL-18 on VEGF production [
Treatment of chondrocytes with curcumin suppresses IL-1β-induced NF-κB activation via inhibition of IκBα phosphorylation, IκBα degradation, p65 phosphorylation and p65 nuclear translocation [
Curcumin is also able to antagonize the IL-1β and TNF-α-dependent up-regulation of MMPs and COX-2. Curcumin has been shown to inhibit the inflammatory and apoptotic effects of IL-1β on chondrocytes and this correlates with down-regulation of NF-κB-specific gene products that are known to mediate inflammation, degradation and apoptosis of chondrocytes in OA. Additionally, both curcumin suppressed IL-1β-induced down regulation of the cartilage specific ECM component collagen type II and of the cartilage specific master transcription factor Sox-9. Furthermore, inhibition of NF-κB activation by curcumin occurs mainly through the IKK inhibition [
When considering the biological effects of curcumin in cartilage and synovial cells and joint tissues, the overriding question is whether curcumin is safe. The research conducted to date with curcumin suggests that it has a good safety record. However, this is not supported by clinical evidence and data from clinical trials. Another important and largely neglected issue is the bioavailability of curcumin and curcuminoids, which is poor generally. Enhancing the bioavailability of curcumin is an important and goal and is likely to bring this promising natural product to the forefront of therapeutic agents for treatment of human diseases [
Its anti-catabolic effects, namely reducing degradative enzyme expression and activity, and its positive influence on anabolic gene expression suggests that it may be a suitable adjunct to conventional pharmaceutical (
There are currently no registered clinical trials of curcumin in OA. "Curcumin in Rheumatoid Arthritis" (ClinicalTrials.gov [
The major problem associated with the use of curcumin as a drug is its low bioavailability. A recent study has attempted to enhance the bioavailability of curcumin by complexation with phosphatidyl choline followed by pharmacokinetic studies in rats [
Another area of interest is enhancing the topical delivery of curcumin [
There is increasing interest in using curcumin in conjunction with NSAIDs to reduce the dosage of NSAIDs. Banerjee
Resveratrol or
Studies in the rat suggest that resveratrol is absorbed in the duodenum. However, resveratrol-glucuronide was the major form absorbed when compared to the minute amounts of unconjugated resveratrol and resveratrol-sulfate [
As discussed earlier many inflammatory factors involved in arthritis, are regulated by the transcription factor Nuclear Factor-κB (NF-κB) [
Resveratrol is a potent inhibitor of the dioxygenase activity of lipoxygenases. Lipoxygenases are dioxygenases with peroxidase activity involved in the synthesis of mediators for inflammatory, atherosclerotic, and carcinogenic processes. Additionally resveratrol can inhibit lipoxygenases through being oxidized by their peroxidase activity. Resveratrol and its oxidized form can act as inhibitors of the dioxygenase activity of lipoxygenase [
The phenomena that inflammatory cytokines such as IL-1β and TNF-α stimulate matrix degrading enzymes such as matrix metalloproteinases (MMPs) and cyclooxygenase-2 (COX-2), through activation of NF-κB, leading to cartilage matrix destruction, joint inflammation and play an important part in pathogenesis of RA and OA [
There is increasing evidence to show that resveratrol may act on the sirtuin system. The silent information regulator (SIR) genes (sirtuins) comprise a highly conserved family of proteins. SirT1, the first member of the sirtuin family, is an enzyme that deacetylates proteins that contribute to cellular regulation (reaction to stressors, longevity). Two recent review articles have examined the published research on resveratrol's effects on the expression and function of sirtuins [
Limbrel [
Nutrigenomics is an exciting area of research that holds much promise for the development of novel therapeutic strategies for the treatment of inflammatory diseases. However, wider acceptance of nutritional intervention, dietary supplements and nutraceuticals by medical practitioners arthritis patients and the scientific research community will require multi-disciplinary approaches that combine original hypothesis driven research with well-designed basic, clinical and epidemiological studies. The published data supporting the anti-inflammatory and anti-catabolic effects of curcumin and resveratrol and their synergistic activity is quite robust. Recent work has shown that curcumin and resveratrol protect chondrocytes from the catabolic actions of IL-1β including MMP-3 up-regulation, inhibition of collagen type II and down-regulation of β1-integrin expression. These phytochemicals can blocks IL-1β-induced proteoglycan degradation, AP-1/NF-κB signaling, chondrocyte apoptosis and activation of caspase-3. Therefore phytochemicals may be a beneficial complementary treatment for OA. However, more basic research is required to understand the absorption and bioavailability of these compounds and gain a deeper insight into their functional effects. In addition, the basic research needs to be followed by well-designed and conducted clinical trials that meet the current expectations of food and drug agencies in Europe and North America.
The European Food Safety Authority (EFSA) [
For function claims: To maintain or to improve a function
For reduction of disease risk claims: To reduce a risk factor for the development of a human disease (not reduction of the risk of the disease)—a risk factor that may serve as a predictor of development of that disease
According to these new guidelines only clinical trials designed to demonstrate a beneficial physiological effect on joints or a reduction in joint degradation in people without OA should be accepted as indicative. These guidelines present some major new challenges to the scientific and clinical communities. Furthermore, they create a number of opportunities for new types of clinical trials. Since the maintenance of a "normal joint" is considered to be a beneficial physiological effect, possible outcomes related to joint structure and function may include changes in:
Joint space width on radiographs
Joint discomfort (
Studies performed in non-diseased (including high risk) population subgroups in which the incidence of OA is the outcome measure could be used for substantiation of health claims relating to the normal maintenance of the joint. Whilst attempting to address these requirements, we need to discriminate between food and non-food supplements. Studies dealing with "non-foods" will require a much more traditional pharmacological design compared to studies on "foods". Clearly, addressing this issue requires new strategies and large scale clinical studies lasting several decades. Such new trials will require radical rethinking of the concept of clinical trials in the OA research community. Human studies appear to be central for substantiation of clinical data and study groups should be representative of the entire population. Hierarchy of evidence is also considered; for example interventional studies are of greater significance compared to observational studies and reproducibility of the effect much be demonstrated. In addition, demonstrating efficacy of food supplements to EFSA will also require data on tolerance and safety, specifically gastric tolerance, hepatotoxicity, renal toxicity and allergenicity. Once these important obstacles have been overcome and new clinical trials have been carried out, curcumin and resveratrol may become useful alternative adjuncts to the NSAIDs that are currently used for the treatment of OA.
Structure of human articular cartilage. This figure illustrates a sample of human cartilage from a tissue microarray developed by the Cooperative Human Tissue Network (CHTN) [
Molecular composition of the ECM of articular cartilage. The major collagenous and non-collagenous components of the territorial and interterritorial cartilage ECM are illustrated.
Summary of the major molecular and cellular changes that occur in the synovial joint during inflammation in OA. Summary of the major synovial, chondral and subchondral changes observed in OA. This schematic also highlights the actions of various white blood cells and inflammatory mediators in OA. Chondral changes include cartilage fragmentation (fibrillation), cartilage degradation and loss of collagen type II and glycosaminoglycans, chondrocyte apoptosis (hypocellularity) and matrix mineralization. Synovial membrane changes in OA include inflammation, synovial hypertrophy, recruitment and activation of T cells, macrophages and fibroblasts, production of matrix metalloproteinases (MMPs) and reactive oxygen species (ROS). Synovial fluid alterations in OA include accumulation of MMPs and ROS, release of IL-1β, TNF-α and other proinflammatory cytokines (IL-6, IL-8), release of inflammatory pain mediators such as prostaglandin E2 (PGE2), formation of degradative products and microcrystals. Subchondral alterations in OA include subchondral sclerosis (
Schematic of the effects of curcumin on the TNF-α receptor and its downstream signaling pathway. The biochemical pathway illustrated here was generated by text mining and makes use of a collection of canonical Ariadne pathways in addition to MedScan text mining.
Proinflammatory cytokines involved in OA.
|Increase cartilage degradation and bone resorption
|Inhibit glycoprotein and collagen synthesis.
|Upregulate MMP expression
|Stimulate other cells to produce proinflammatory cytokines and growth factors
|Stimulate proangiogenic factor release
|Stimulate other cells to produce chemotactic cytokines
|Stimulate Nitric Oxide (NO) production
|Induce chondrocyte apoptosis
|Increase cartilage degradation and bone resorption
|Inhibit proteoglycan synthesis
|Upregulate MMP expression
|Production of proteolytic enzymes
|Stimulate other cells to produce proinflammatory cytokines
|Stimulate other cells to produce chemotactic cytokines
|Stimulate proangiogenic factor release
|Stimulate NO production
|Induce chondrocyte apoptosis
|Inhibit proteoglycan synthesis
|Reduce chondrocyte proliferation
|Increase MMP-2 activity
|Increase aggrecanase-mediated proteoglycan catabolism
|Recruits leucocytes
|Neutrophil chemoattractant
|Stimulates release of proinflammatory cytokines
|Hypertrophic differentiation and calcification of chondrocytes
|Induce NO synthesis
|Induce MMP synthesis
|Increase production of IL-1β, Il-6 and IL-8
|Stimulate release of proangiogenic factors
|Stimulate release of proinflammatory cytokines
|Stimulate angiogenesis
|Induce NO synthesis
|Synovial hyperplasia and inflammatory cell recruitment
|Induce chondrocyte apoptosis
|Reduce expression of cartilage matrix components
|Up-regulate fibronectin- a mediator of cartilage destruction
|Leukaemia Inhibitory Factor (LIF)
|Synovial fibroblasts Chondrocytes
|Stimulate proinflammatory cytokine expression
|Increase pro-MMP-2 synthesis
|Increase MMP-13 synthesis and activity
|Increase cartilage resorption
|Decrease proteoglycan synthesis
|Leukocyte infiltration into synovial fluid
|Increase cartilage degradation when in combination with IL-1β and TNF-α


text:
Employment Ads
|Cognitive and Social Neuroscience
The Ohio State University
|Columbus, OH
| The Department of Psychology at THE OHIO STATE UNIVERSITY seeks outstanding candidates for two faculty positions for individuals using brain imaging methodologies. For the position in (1) cognitive neuroscience, candidates investigating any area of higher order cognitive or mental processes (e.g., learning and memory, decision making) who use functional magnetic resonance imaging (fMRI) as a core methodological tool are encouraged to apply. For the position in (2) social neuroscience, candidates investigating any area within social psychology (e.g., attitudes, social cognition, relationships, etc.) who use fMRI as a core methodological tool are welcome. A state of the art MRI facility with a research dedicated Siemens Trio scanner including all of the necessary ancillary equipment to conduct both structural and functional imaging studies opened within the psychology building in 2011. Pending the availability of funds, these tenure-track positions may be filled with a person at any career stage. Applicants must have earned a Ph.D. in psychology or a related field prior to the employment start date. All applicants are expected to have strong and fundable research programs and to contribute to both graduate and undergraduate supervision and instruction. All applicants should submit a cover letter, curriculum vitae, and three letters of recommendation. Junior candidates should also include selected reprints and a statement of research and teaching interests. Inquiries for the cognitive neuroscience position should be directed to Stephanie Fowler (firstname.lastname@example.com). Inquires for the social neuroscience position should be directed to Paula Cullen (email@example.com). Review of applications will begin on October 1, 2013 though applications will continue to be accepted until the position is filled. Please apply online through Academic Jobs Online at: http://academicjobsonline.org. The Ohio State University is an EEO/AA employer. Women, minorities, Vietnam-era veterans, disabled veterans and individuals with disabilities are encouraged to apply. Ohio State is an NSF Advance Institution.
When applying for this position, please mention you saw this ad in the APS Employment Network.
|Ad has been online since August 28, 2013


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"These questions will uncover secrets that could sabotage your relationship and will draw you closer than you ever imagined (but they will also quickly reveal if you are not truly compatible)"
I have put together 1,000 of the most important questions couples should ask each other. These are questions that go beyond small talk and simply making conversation like you will find in most "questions" books. You will NOT find questions like "if you were a color, what color would you be" or "what is your most embarrassing moment".
If you and your partner answer these 1000 questions, I guarantee that you will know each other better than 99% of couples on the face of the earth.
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York Street gardens will close at 3 p.m. on Friday, July 21 for a concert. Other early closings.
If you are like me, right now you are politely thanking summer for all its delights, and telling it to get lost already—it's Fall! I went in search of autumn in the Gardens this week, and found the beginnings, as well as plenty of summer color to enjoy. Do be sure to come visit one last time (or two) before first frost—the landscape definitely changes after that, and it could happen any day now.
Summer Color
The landscape is vibrant with color and busy with bees and butterflies stocking up for the winter months. This globe amaranth (Gomphrena) made the perfect landing pad for a butterfly, and can be found lining the planters between Shady Lane and the Orangery.
Rabbit Brush (Chrysothamnus) lights up its surroundings at the very end of summer with brilliant yellow flowers, and attracts multitudes of bees. See it in the Rock Alpine Garden, at Chatfield, and elsewhere around the Gardens.
In the Japanese Garden, the bush clover (Lespedeza) is blooming in magenta drifts.
And can you resist this sky blue morning glory (Ipomoea), growing in Le Potager?
Fall Color
To see that fall really is around the corner, take a long view of the grounds from the Green Roof or the Mordecai Children's Garden; you'll see how the trees and grasses are heading towards golden.
Or take an up-close look at early turners such as the buckeyes (Aesculus glabra) in South African Plaza, or Euonymous in the Japanese Garden.
And admire the orange berries of mountain ash (Sorbus aucuparia) in the Rock Alpine Garden and elsewhere. This is just the beginning of the fall palette; come back for much more over the next couple months!


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Re-live the 2010 season through the words of Aaron Rodgers, Mike McCarthy and Charles Woodson in the latest installment of the NFL Films-produced, Emmy Award-winning series, America's Game: 2010 Green Bay Packers exclusively on NFL Network.
America's Game: 2010 Green Bay Packers debuts on Wednesday, September 7 at 9:00 PM ET, one night before the Packers kickoff the 2011 regular season at home against the New Orleans Saints, the previous Super Bowl champs. Featuring exclusive video and sound of the Packers during team meetings, practices, games and inside the locker room, America's Gameoffers an all-access look at the Super Bowl champions. The show is narrated by the Emmy-nominated actor of Mad Men, John Slattery.
In the hour-long special, Rodgers, McCarthy and Woodson recount the inside story of the 2010 season. After a heartbreaking loss to the Arizona Cardinals in the NFC Wild Card game a year before, the Packers entered 2010 with high aspirations. Despite a 3-3 start and injuries to key players, the Packers qualified for the playoffs on the final day of the regular season, sparking a postseason run to the franchise's fourth Super Bowl title.
America's Game, an Emmy Award-winning series, delves deep into the story behind the making of Super Bowl champions. Each episode is a 60-minute documentary in high definition, featuring key members of the winning team telling behind-the-scenes accounts from their championship season. With the signature NFL Films footage, combined with news clips and photos, highlights from team radio broadcasts, inside looks from team meeting rooms, sideline audio and other exclusive features, America's Game provides an epic and intimate portrait of championship teams.
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AMATERASU by peachesroxWatch
©2013-2017 peachesrox
Commission for Phire on CI of their beautiful mare Amaterasu cx
DOWNLOAD FOR FULL QUALITY! dA killed it -.-
DOWNLOAD FOR FULL QUALITY! dA killed it -.-
Stunning. Seriously stunning. That's what I've always strive for. The crisp detail with still a high degree of complexity and creativity. I've been stuck with my art lately, and trying to bring it to the next level but having trouble! I don't have the best tools right now...but I never let that be an excuse. I could learn a thing or two from your art!
Wow thank you so much!! those are quite the compliments! All I can really suggest is to practice lots, and dont be afraid to try something out of your comfort zone! And pay attention to detail. If you look at your image, as yourself "does this horse actually look like its THERE?" if not, why? Then fix the problem. Thats what I do with all my art, I give myself a critique and make sure I fix it before I upload it best of luck to you!
Yes practice practice!! I have to say your mane tutorial has been my favorite so far, because you get really great results without a tablet. Thank you for the advice. And you are so so welcome!
Oh dear that tutorial is so old xD but its very good for getting the graps of hair painting when you're still figuring it out so I'm glad its helping! I keep meaning to make a new one, but I dont have any time!
haha it still holds its own though! I have never been able to paint hair for some reason. Eyes, lighting, coloring. But I could never paint hair! The tutorial was a great first step in getting down the basics for me. And I totally understand about having no time! Just gotta keep trucking along
I love how you don't over smudge and allow it to look more realistic (other than it is a purple and blue horse with scales... XD)
hehe thank you babe! thats a huge pet peeve of mine xD
Gorgeous horse!!
Oh BOY MORE ART TO COMMENT ON
so magical and beautiful and mysterious, gorgeous! ^u^
Oh my, the details and colors bright colors are beautiful and so prettyy
Omg so pretty!


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This review is from: MSI Z87-GD65 Gaming LGA 1150 Intel Z87 HDMI SATA 6Gb/s USB 3.0 ATX Extreme OC High Performance Triple CFX/ SLI Intel Motherboard
Pros: Great board. We have several that have never caused us any issues.
Cons: The recent releases have had an old BIOS V1.8 instead of V1.9, This causes the system to not want to reboot or shutdown when requested by Windows. Spent many hours on tech support with MSI until finally they suggested reflashing the BIOS. That solved the issue. Sad that they would release a board with a bad BIOS on it.READ FULL REVIEW


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Most Skinematic Presidential Race:
Obama Vs. McCain '08
Some say that eyes are the windows into a man's soul. Is our skin a measure of our character? In the campaign for the American Presidency, there was a transformational amount of skin issues to be found...
If John McCain were elected, he would not have been the first American president to have skin cancer. Ronald Reagan had one excised from his nose while in office. Bill Clinton had a similar lesion scraped from his back even as he was running from the Monica Lewinsky scandal. Yet Clinton's and Reagan's skin cancers were basal cell or non-melanoma in nature. Definitely worth treating, but nothing life threatening. Note: The dark lesion seen here is not a melanoma, but probably a benign lesion called a keratosis.
John McCain, either because of his time in a Viet Nam prison camp (hadn't you heard?), or time spent in an Arizona swimming pool, developed for melanoma. Four of them. And, it was revealed in the heat of the race, one of them may have been more aggressive than was previously reported.
The 2008 US Presidential campaign had plenty of notable news items, many of them generated by perky Alaskan Gov. turned VP candidate Sarah Palin. Yet among the moose hunting, child rearing, and trooper gating anecdotes, one bit of trivia went relatively unnoticed. It was revealed that last year, Palin had a tanning bed installed in the Alaska Governor's mansion. Supposedly it was bought used and paid for by the Palin's. But unlike Sarah the Governor's wardrobe shopping spree, the cost of the unit and installation is not what worries us. While some use tanning beds attempting to limit the depressive symptoms caused by a sun-free Alaskan winter, is it really worth the risk to the skin?
Before Palin attempts to brown her skin or end up with a red burn (possible in supposedly "safe" devices), we'd suggest she look into the data showing increased melanoma skin cancer rates in women using tanning beds. Perhaps a chat with former running mate John McCain would steer her straight. We recommend dietary sources of vitamin D like fortified milk, soy drinks, fish and egg yolks. And as for tanning, we suggest Sarah keep the "pale" in Palin: Just Say No!
During the campaign, some voiced concerns about the level of experience shown by Senator Barack Obama. Did he have the maturity to handle the role of Commander in Chief? At skinema.com, we don't pretend to be politically savvy. But in dermatology, we know age like the back of our hand (D'Oh! Is that a sun spot?)
Note the small dark bumps on Obama's cheeks. These lesions are known as DPN's, short for dermatosis papulosa nigra. These non-cancerous lesions are not due to diet, healthy or otherwise. The sun, even the intense solar radiation that Obama was exposed to growing up in Hawaii, is not the culprit either. Seen more often in people of color, these discrete dots are a marker for maturity, age, or to put it nicely...experience.
|Can skin doctors remove these spots, enact this change? Yes, we can. Treatment requires lightly zapping the lesions with a low strength cauterizing device. Lasers can also be used to transform a transformative politician. We presume Obama has other items on his to-do list. So from a skin perspective, we can confirm: Obama has experience to spare.
Finally, did VP Elect Joseph Biden have a hair transplant like last year's Skinnies winner Nicolas Cage? Clearly, the dermatologic focus of the new administration will continue...
© 1996-2009 Vail Reese M.D.


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Sea ice in the Arctic is disappearing at a far greater rate than previously expected, according to data from the first purpose-built satellite launched to study the thickness of the Earth's polar caps.
Preliminary results from the European Space Agency's CryoSat-2 probe indicate that 900 cubic kilometres of summer sea ice has disappeared from the Arctic ocean over the past year.
This rate of loss is 50% higher than most scenarios outlined by polar scientists and suggests that global warming, triggered by rising greenhouse gas emissions, is beginning to have a major impact on the region. In a few years the Arctic ocean could be free of ice in summer, triggering a rush to exploit its fish stocks, oil, minerals and sea routes.
The consequences of losing the Arctic's ice coverage, even for only part of the year, could be profound. Without the cap's white brilliance to reflect sunlight back into space, the region will heat up even more than at present.
As a result, ocean temperatures will rise and methane deposits on the ocean floor could melt, evaporate and bubble into the atmosphere. Scientists have recently reported evidence that methane plumes are now appearing in many areas. Methane is a particularly powerful greenhouse gas and rising levels of it in the atmosphere are only likely to accelerate global warming.
And with the disappearance of sea ice around the shores of Greenland, its glaciers could melt faster and raise sea levels even more rapidly than at present.
Professor Chris Rapley of UCL said: "With the temperature gradient between the Arctic and equator dropping, as is happening now, it is also possible that the jet stream in the upper atmosphere could become more unstable.
That could mean increasing volatility in weather in lower latitudes, similar to that experienced this year."


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Fylde Fire Systems are a professional fire alarm systems installer based in Cleveleys and operating throughout Preston and the Fylde Coast. We stock a wide range of fire alarms, emergency lighting, nurse call paging, early warning smoke detection and fire check doors in Preston and Cleveleys and the Fylde Coast.
We understand the importance of early warning smoke detection systems in preventing fire damage and have a wide range of alarms available to clients in Cleveleys and Preston at a competitive price. Supplied & fitted to comply with the latest British standards & IEE regulations.
The Electrical Contractors Association. Businesses and consumers alike cannot afford to take risks when appointing electrical contractors. For peace of mind, ensure your electrical system is designed, installed, inspected, tested and maintained by an ECA registered Member.
The Institute of Fire Prevention Officers. One of the aims of the Institute is to enable all members to constantly maintain a professional approach to fire safety.
33 Beach Road
VAT Registration No. 155 4374 60


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Could the same user list that is used for the PPTP VPN be used for this
Should the number of users on the PPTP list limited in the same manner (and
for the same reason)?
Just food for thought...
James W. McKeand
-----Original Message-----
From: Dinesh Nair [mailto:dinesh at alphaque dot com]
Sent: Monday, September 13, 2004 12:19 AM
To: Mitch (WebCob)
Cc: Bernie Kucharski; m0n0wall at lists dot m0n0 dot ch
Subject: Re: [m0n0wall] m0n0wall embedded with RADIUS Server
On 11/09/2004 09:17 Mitch (WebCob) said the following:
> Maybe you want to consider some sort of lighter weight access control
> system and a modification to dinesh's captive portal concept to use
> it? Just a thought.
one idea i've been mulling around with is to have a simple user/password
database on the m0n0wal for captive portal users to authenticate against.
if this is implemented, i'd probably limit the number of users to a small
number like 16 or 32 to begin with. anything more than that, and it may make
more sense to go the RADIUS route.
Regards, /\_/\ "All dogs go to heaven."
dinesh at alphaque dot com (0 0) http://www.alphaque.com/
| for a in past present future; do |
| for b in clients employers associates relatives neighbours pets; do |
| echo "The opinions here in no way reflect the opinions of my $a $b." |
| done; done |
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|Jeffs End Season with Heartbreaking 1-0 Loss to Bowdoin
Jeffs End Season with Heartbreaking 1-0 Loss to Bowdoin
November 4, 2006
BRUNSWICK, ME – The Amherst College field hockey team entered its NESCAC semifinal match-up with Bowdoin College winning six of its last seven games, but ended its great run with a 1-0 loss to the Polar Bears. The Lord Jeffs finish their season at 8-8 after starting 2-6, while the Polar Bears improve to 14-1 and will try to defend their NESCAC title on Sunday.
The Amherst offense failed to put anything together in the first half, but its defense stepped up and held Bowdoin scoreless, going into halftime tied at 0-0. Bowdoin's defense shut down the Lord Jeff offense in the second half as well, and did not allow a single shot in the entire game. The Polar Bears' offense finally capitalized midway through the second half when sophomore Lindsay McNamara (Milton, MA) scored the eventual game-winning goal.
The Lord Jeff defense did all it could in the game, holding Bowdoin to just one goal despite the Polar Bears having more than ten penalty corners. Junior goalie Kathleen Boucher (Washington, DC) anchored the defense, recording nine saves in the effort.
Despite Amherst's season being over, the Lord Jeffs finished the 2006 campaign as one of the hottest teams in the NESCAC, and will hope to carry that momentum into the 2007 season.
|Amherst College > Athletics > Field Hockey >Jeffs End Season with Heartbreaking 1-0 Loss to Bowdoin


text: Additional information about AIG can be found at www.aig.com | YouTube: www.youtube.com/aig |Twitter: @AIG_LatestNews| LinkedIn: http://www.linkedin.com/company/aigAIG is the marketing name for the worldwide property-casualty, life and retirement, and general insurance operations of American International Group, Inc. For additional information, please visit our website at www.aig.com. Products and services are written or provided by subsidiaries or affiliates of American International Group, Inc. (AIG). Not all products and services are available in every jurisdiction, and insurance coverage is governed by actual policy language. Certain products and services may be provided by independent third parties under contract with AIG or its subsidiaries or affiliates. Insurance products may be distributed through affiliated or unaffiliated entities. In Europe, the principal insurance provider is AIG Europe Limited.


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This Roland Sands Womens CE back armour allows you to increase the safety performance of your Roland Sands jacket. Specifically designed for the Roland Sands jackets, this back protector will provide a great level of protection for this vulnerable area. The protector will simply slot into the back pocket of your jacket to instantly increase the level of safety provided.
- CE approved
- Measures approximately 35.5cm in height and 20cm in width
All UK PURCHASES OF A TOTAL VALUE OF £50 OR MORE CAN ENJOY FREE SHIPPING.
All UK PURCHASES OF A TOTAL VALUE OF £100 OR MORE CAN ENJOY FREE RETURNS.
All UK orders that total less than £50 will be charged £4.92. We offer discounted international delivery because we absorb some of the delivery costs to all international destinations so you get the very best value. Please note that non EU customers do not pay VAT. Examples of international delivery costs can be found on our delivery information page. Please note that internatonal customers are repsonsible for any import duties that may be payable and to ensure that the products you have ordered can be imported into your country.
All UK customers receive a 1hr delivery window by text and email (if provided) for your convenience and improved first time delivery success.
All items that are in stock will be dispatched the same day for next day delivery in the UK. International deliveries will take longer. If an item isn't in stock you will receive an email to let you know when to expect to receive it.
Our prices are the most competitive around, and we regularly check our prices to keep it that way. That's why we will promise that should you find any of our products at a lower price anywhere else, we'll match that price AND give you a free thermal neck collar worth £14.99. So rest assured you can buy from us with confidence. If you have found this product cheaper elsewhere please email us. More information can be found in our T&Cs.


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Mark up websites, graphics, and photos, or start brainstorming on a blank canvas. Browse the web with your friends or make that conference call more productive than ever. No plug-ins, downloads, or firewall voodoo - it's all here, ready to go when you are. Browser-agnostic, user-friendly.
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Muhammed "King Mo" Lawal and Mark Kerr. Photo courtesy of M-1 Global.
The official weigh-in results for tonight's M-1 Breakthrough event, the historic Memorial Hall in Kansas City, Missouri, are below. All fighters made weight with the exception of Ferrid Kheder, who came in four pounds over the lightweight limit and will be docked 10% of his purse.
In addition, heavyweight Rogent Lloret will be permitted to weigh-in later today due to visa issues and a women's bout between Andria Caplan and Mollie Ahlers-Estes will now be fought at a catch-weight of 155 lbs and has subsequently been switched from a professional fight to an amateur bout.
Continue reading "Lawal, Kerr on Weight for M-1 Breakthrough"
Fedor Emelianenko. Photo courtesy of Affliction Entertainment.
Former PRIDE heavyweight champion Fedor Emelianenko will make his Strikeforce debut this fall in a heavyweight showdown with EliteXC veteran Brett "The Grimm" Rogers. No date or venue has been announced but the fight is expected to occur during the fall.
Last month, Emelianenko was slated to fight PRIDE veteran Josh Barnett at Affiction: Trilogy before the promotion ceased operations and canceled the card.
Continue reading "Fedor-Rogers Booked For Fall"
Longtime heavyweight king and new Strikeforce acquisition Fedor Emelianenko will be part of an open workout session this Wednesday in New York City. The event is free and open to the public, fans and media alike.
The festivities, which will also include a meet-and-greet and an autograph session with Emelianenko, is slated to begin at 3:30 PM ET at the Fighthouse MMA gym, which is located at 122 West 27th Street, 2nd Floor in Manhattan.
Continue reading "Strikeforce, Fedor to Hold Open Workout in New York City on Wednesday"
Muhammed "King" Mo Lawal. Image courtesy of AllElbows.com.
M-1 Global has released the finalized card for its "Breakthrough" event, which will be held at the historic Memorial Hall in Kansas City, Kansas on Friday, August 28. The six-fight main card will be televised live on HDNet in the United States and through Internet PPV internationally.
Standout wrestler and fast-rising heavyweight prospect Muhammed "King" Mo Lawal will headline the show against former UFC and PRIDE standout Mark Kerr. A special sparring exhibition between longtime heavyweight king Fedor Emelianenko and training partner Gegard Mousasi will also take place.
Continue reading "M-1 Global Announces Complete Fight Card for "Breakthrough" on Aug 28"
M-1 Global has officially announced that their August 28th show titled "Breakthrough" has been moved the Los Angeles Convention Center to the historic Memorial Hall in Kansas City. The show will feature a main event of Mo Lawal vs. Mark Kerr along with an exhibition match featuring Fedor Emelianenko and Gegard Mousasi.
The show was originally set to feature a main event of Don Frye vs. Mo Lawal but unfortunately Frye has pulled out and will be replaced by Kerr. "Don Frye had a signed contract with M-1 and part of that signed commitment allowed us to change the venue if needed," said M-1 COO Raimond. "From our perspective, Don should still be in this fight. However, for reasons that we aren't exactly sure of, he has backed out. Don still has not provided us with a clear reason as to why he is refusing to fight.
Continue reading "Frye Out; Lawal to Face Kerr at M-1 Global: Breakthrough"
Fedor Emelianenko, Tom Atencio, and Donald Trump. Photo courtesy of Affliction Entertainment.
After a week of speculation, Fedor Emelianenko has put the rumors to rest as the former PRIDE heavyweight champion signed a multi-fight agreement that will see him headline events co-promoted by Strikeforce and M-1 Global.
Emelianenko's debut under the Strikeforce M-1 banner is expected to come this Fall on Showtime.
Continue reading "Fedor Signs; To Appear on Events Co-Promoted by Strikeforce and M-1 Global"
It was supposed to be different this time around.
With the collapse of Affliction complete and the list of suitable non-UFC opponents dwindling, the top heavyweight in the world, Fedor Emelianenko, seemed likely to finally sign with the Ultimate Fighting Championship. However despite early reports suggesting that a deal was imminent, we stand here with the two sides as distant as ever, and it comes as no surprise.
Continue reading "Blame the Past for Fedor, UFC Drama"
Fedor Emelianenko. Photo courtesy of BodogFight.
Despite published reports stating that a deal was nearly complete, perennial heavyweight king Fedor Emelianenko remains a free agent and not part of the Ultimate Fighting Championship's ever-growing heavyweight roster.
Emelianenko and his manager, M-1 Global figurehead Vadim Finkelchtein, held a press conference today in Anaheim, California to discuss the recent rumors and a variety of topics. It was also announced that Emelianenko will serve as the featured athlete in EA Sports' first-ever MMA-related video game, "EA Sports MMA", which is scheduled to be released next year.
Continue reading "Fedor to Head EA Sports MMA Roster, Deal With UFC Far From Finished"
Differing reports issued today are insinuating that longtime heavyweight king Fedor Emelianenko may or may not be close to a deal that would finally land him inside the confines of the UFC.
Lance Pugmire of the Los Angeles Times reported Tuesday afternoon that Emelianenko's management team and the UFC were finalizing a contract that would reportedly be announced as early as this coming Friday. However, Sports Illustrated's Josh Gross is now quoting M-1 Global's Apy Echteld as dismissing Pugmire's story as "inaccurate".
Continue reading "Are Fedor and the UFC Close to a Deal?"
Seal Beach, CA - The highly anticipated fight between Fedor Emelianenko and Josh Barnett at the Affliction Trilogy MMA show has been cancelled. The mega fight was scheduled to take place at the Honda Center in Anaheim on August 1st. The unforeseen license denial of Josh Barnett gave Affliction limited time to find a replacement and adequately promote the new main event.


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Beyonce Knowles Pictures With Daughter Blue Ivy Carter
Beyoncé Knowles and Daughter Blue Ivy Hit the NYC Streets
Start Slideshow
Beyoncé Knowles and Daughter Blue Ivy Hit the NYC Streets
Beyoncé Knowles carried her daughter, Blue Ivy Carter, around NYC today. The girls were accompanied on the walk by Blue Ivy's grandmother Tina Knowles. It was their latest city outing after a recent jaunt to Brooklyn. Beyoncé, Blue, and Tina went to Prospect Park last Friday for a fun afternoon of chilling with friends. Beyoncé and husband Jay-Z had a big weekend. On Saturday, they helped celebrate Robin Thicke's 35th birthday at Catch with Paula Patton and Russell Simmons. Also, Jay-Z and Beyoncé checked out a The-Dream concert at the small club SOB's yesterday.