text:
The Pauahi Foundation administers scholarships that have been created by private donors and awards these scholarships supporting college level areas of study, as well as trade and vocational courses. Many awards may be determined based on merit, while some include specific criteria such as geographic location, field of study, financial need or grade point averages.
Scholarships are available to the general public, including graduates of Kamehameha Schools. Foundation scholarships are supplemental and may not cover the full cost of education. Students are also encouraged to apply for educational financial assistance from state, federal, and private funds and contribute from their own earnings. Foundation awards are subject to availability of funds.
Before proceeding, please read all Pauahi Foundation Scholarship online materials. The online materials identify the processes you must follow and deadline dates you must comply with in order to be considered for any scholarship. Your failure to follow process instructions and comply with all deadlines will result in you not being considered for any scholarship. The Pauahi Foundation reserves the right to make decisions in its sole discretion, and its decisions in regards to the selection and awarding of scholarship funds is final.
The Pauahi Foundation's policy is to give preference to applicants of Hawaiian ancestry to the extent permitted by law. See Hawaiian Ancestry Verification page for further details.
Online application opens: January 3, 2017
Online application closes: February 17, 2017, 4:15pm HST
Program Requirements
Listed below are our general program requirements. Individual scholarship funds will require the applicant to meet other conditions. Review the Scholarship Listing for specific requisites. Applicant must:
- Be a classified, degree-seeking student
- Be attending an institution in Hawai`i or the continental U.S.
- Be attending school as a full-time student unless specifically noted in the Scholarship Listing
- Be attending a two- or four-year accredited* institution
All documents must be received (not postmarked) at the Foundation office by February 17, 2017, 4:15pm, HST. Late documents will not be accepted and will not be considered for any scholarships. All documents, once submitted will become property of the Foundation and will not be returned.
Please use the checklist below to aid you in completing the application process.
Required Documents:
__ Online Application – Completed and have clicked the green "Submit" button
- Includes three mandatory essay questions
- Selection of scholarship funds
- Any additional essay questions and
supplemental documents
__ Official Transcripts
- Current high school seniors must have their high school registrar send an official record of transcript to the Pauahi Foundation
- Current college students must have their institution's records office send an official record of transcript to the Pauahi Foundation after fall 2016 grades have been posted
__ Copy of college Acceptance Letters
- Current high school seniors must submit a copy of a college acceptance letter
- College students transferring to another institution must submit a copy of the new college acceptance letter
- College graduates matriculating to a graduate program or higher must submit a copy of either their application to the graduate program or a confirmation of application to the graduate program. If awarded, confirmation of full acceptance will be required before funds are released
__ Letters of Recommendation
- As required by the specific fund
__ Student Aid Report (SAR)
- From Free Application for Federal Student Aid (FAFSA) as required
__ Art Portfolio – as required.
- Submit a hard-copy portfolio of pictures of works of art. The portfolio will remain with the Foundation as part of your application packet and will not be returned.
Submit all documents to:
Pauahi Foundation
567 South King Street, Suite 160
Honolulu, HI 96813


text:
Yannick Laurent
Sky Fighters
After a French-built fighter jet disappears from an air show, ace pilots "Walk'n" Marchelli (Benoit Magimel) and "Fahrenheit" Vallois (Clovis Cornillac) are called upon to foil a terrorist plot. On a top secret mission to shoot down al-Qaida kamikaze planes, the flyboys barrel into thrilling dogfights against F-16s over desert terrain. Breathless aerial cinematography using actual military pilots distinguishes this Top Gun-style thrill ride.

subset: commoncrawl


text:
Free Newsletters - Space - Defense - Environment - Energy
by Staff Writers
Helsinki, Finland (SPX) Nov 11, 2013
With more than a billion cows around the world, an immense amount of dung is produced each day. Most of these droppings will evidently disappear, as the world is still green rather than brown. Now a team of scientists have joined forces with local volunteers to find out who decomposes the most of it in Finland, Northern Europe.
The largest part of a dung pat is broken down by microbes alone, or just evaporates as the pat dries out. About one-eighth (13%) is removed by small animals, mostly insects and other invertebrates.
Not all of these animals are equal: Of all the bugs making a living off the dung, large tunnelling Dor beetles in the genus Geotrupes removed dung twice as fast as did smaller dung-dwelling beetles and earthworms.
Climate proved to have an equally strong effect on dung disappearance as does dung-eating animals.
Citizen scientists did the job
Clearly, no single team of professional scientists could work at this scale. To achieve it, the team used the approach of citizen science.
"Citizen science is about having non-scientists joining in the research process. Together we can then form the big picture" explains Riikka Kaartinen, who kept the whole project together.
Strength in numbers
"What we did was to take citizen science one step further, by moving from 'just' observing nature to manipulating something, to excluding certain groups of animals" says Tomas Roslin, the leader of the research group. "Changing something and looking at the consequences, that is the gist of experimental science."
"The thing to learn here is that we can do so much more if we just think outside of the scientists' box", adds Tomas. "In citizen science, our own imagination is really the hardest limit to what we can do together."
Kaartinen, R., Hardwick, B., and Roslin, T. 2013. Using citizen scientists to measure an ecosystem service nationwide. Ecology 94: 2645-2652.
Related Links
University of Helsinki
Farming Today - Suppliers and Technology
|The content herein, unless otherwise known to be public domain, are Copyright 1995-2014 - Space Media Network. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA Portal Reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. Advertising does not imply endorsement,agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. Privacy Statement


text:
Tired of default blank, non-informative Finder's icons for your Book files? This app is for you!
E-Books Finder Icon Generator is a utility that allows you to customize your E-Books folders with cool icons. The icons are generated on-the-fly from your book cover images.
E-Book formats supported: ePub, ePub3, fb2


text:
Click the yellow pencil on the opening screen and PixelFace becomes a drawing tool with 49 colors and 24 brushes.
Draw anything you like. Here's how:
Select a color, resolution, brush pattern, pixel size, and transparency level, then move the mouse to draw in the white rectangle. To make a line drawing, select the highest resolution, the one-pixel brush, and a small pixel size. (The red circles at the right mark these settings.) Click the green arrows to swap brush menus.Adjust the transparency for interesting overlapping effects and color blends.
If you need to correct something but don't want to start over, just draw right over it with a plain white brush. Click the eraser tool to delete the whole image. The red button draws automatically. The computer and you can draw at the same time. To save your finished picture, capture a screenshot; paste it into any graphics program, word processor, or e-mail application to print.
Copyright © 2004 National Gallery of Art


text:
- 161 total posts
- 1 review
- 160 comments
Reviews & Stories
So far, Dr. Campos has the best results of body contouring, after seeing many pre-op photos of his patients. WOW..he def has talent and I def want that hourglass figure. I am 5'3 and currently weigh 165lbs. I am trying to lose 10 to get to my personal ideal weight of 155lbs before July 13. I love the fact that Campos can make majority of his patients have the Coca-Cola bottle... READ MORE
Recent comments from PinaywitAZZ
You'll truly love him! He REALLY cares for our well being!!!! Him & his staff!!!!! READ COMMENT
Sounds good! Who'd you book with? Either way, I'm glad you decided to stay at a recovery home!!!!! Good call!!!! Take care Lady! And blessings to ya!!!!! READ COMMENT
Hey Phat!!!! Hope you're well!!! READ COMMENT
Immajustdoit!!!! Hey there!!!! You've been contemplating for awhile huh? Nice to see ya on here!!!! December???? Cool! I'm gonna wait until tax season! BUT I've been contacting Nadia (team Pantoja) back and forth, sometimes to ask for... READ COMMENT
I feel great! I have a bounce in my step, confidence levels are huge. Being able to fit in clothes, to be able to bend over without losing my breath is wonderful!!!! I feel like my inside matches outside ;) READ COMMENT


text:
Project Title: Inductive Modeling of Carbon Fluxes in Lakes and Reservoirs and Implications for the Global Carbon Cycle
Mendenhall Fellow: Cory McDonald, (303) 541-3056, firstname.lastname@example.com
Duty Station: Boulder, CO
Start Date: October 25, 2010
Education: Ph.D., Environmental Engineering, Michigan Technological University (2010)
Research Advisor: Rob Striegl, (303) 541-3091, email@example.com
Project Description: Current models of regional- to global-scale carbon cycling typically assume that the role of inland water bodies (lakes, ponds, and reservoirs) is negligible. However, only about half of the carbon delivered to these water bodies is exported to the oceans; the remainder is either buried in sediments or lost to the atmosphere as CO2 and CH4 (Cole and others, 2007). While lakes and reservoirs contain a relatively small volume of water and occupy a relatively small portion of the landscape, they represent "hot spots" for biogeochemical carbon cycling. Carbon burial in lakes and reservoirs is estimated to be several times larger than in the oceans (Downing and others, 2008; Dean and Gorham, 1998), and the amount of methane evasion from lakes is also likely greater than that from the oceans (Bastviken and others, 2004). Current large-scale estimates of net carbon fluxes and sequestration in inland waters are coarse, however, and a refined model of these systems is required.
Figure 1. Major carbon fluxes in lakes and reservoirs: (1) air-water gas (CO2 and CH4) exchange, (2) surface water inflow plus atmospheric C inputs, (3) groundwater seepage (4) phytosynthetic uptake of dissolved inorganic carbon, (5) respiration, (6) settling of particulate organic carbon, (7) sediment C burial, (8) methane evasion, (9) calcification (biotic and abiotic), (10) tributary outflows, and (11) groundwater outflows.
A number of factors influence the amount of organic and inorganic carbon delivered to a given lake, including land use and land cover in the catchment and upstream, surface and groundwater hydrology, climate, and geomorphology. In-lake fate and transport processes are also regulated by many interrelated factors, including primary productivity, water chemistry, hydrologic setting, climate, and bathymetry (fig. 1). Given the complexity of the problem, an exceedingly large number of calibration data (that is, measurements describing whole-lake carbon budgets) would be required to properly constrain a process-based model (McDonald, 2010). Relatively few of such whole-lake budgets have been compiled to date. Thus, an inductive, data-based approach utilizing artificial neural-networks (ANNs) is being developed to utilize readily quantified and widely available geospatial data (for example, lake area, base flow, land cover, geology, and so on) to characterize carbon efflux and burial. The model will then be applied to estimate carbon budgets for all of the water bodies mapped in the national hydrography dataset (NHD) and corrected for small, unmapped waterbodies. Finally, an estimate of carbon efflux and sequestration for the nation's inland water bodies will be made.
Bastviken, D., Cole, J., Pace, M., and Tranvik, L., 2004, Methane emissions from lakes: Dependence of lake characteristics, two regional assessments, and a global estimate: Global Biogeochemical Cycles, v. 18, GB4009.
Cole, J., Prairie, Y., Caraco, N., McDowell, W., Tranvik,L.G., Striegl, R.G., Duarte, C.M., Kortelainen, P., Downing, J.A., Middelburg, J.J., and Melack, J., 2007, Plumbing the global carbon cycle: Integrating inland waters into the terrestrial carbon budget: Ecosystems, v. 10, 171–184.
Dean, W., and Gorham, E., 1998, Magnitude and significance of carbon burial in lakes, reservoirs, and peatlands: Geology, v. 26, p. 535–538.
Downing, J., Cole, J., and Middelburg, J., 2008, Sediment organic carbon burial in agriculturally eutrophic impoundments over the last century: Global Biogeochemical Cycles, v. 22, GB1018.
McDonald, C.P., 2010, Improving the reliability of aquatic biogeochemical models: Integrating information and optimizing complexity: Houghton, Mich., Michigan Technological University, Ph.D. dissertation.
Previous Profile Project Profiles Next Profile
URL: http://geology.usgs.gov/postdoc/profiles/mcdonald/index.html
Direct inquiries to Rama K. Kotra at firstname.lastname@example.com
Page Contact Information: Mendenhall Postdoctoral Fellowship Program Web Team
Last modified: 16:08:31 Thu 13 Dec 2012


text:
In his excellent question, Matt reminded me of (almost prehistoric) days when static routes pointing to a connected interface (not IP next-hop) had administrative distance zero. I also remembered that we've had interesting routing problems as those static routes actually behaved like connected routes (and were redistributed into routing protocols with redistribute connected command).
This is no longer the case (and hasn't been since at least IOS release 12.2 ... I wasn't able to find a box running an older release to test it), all static routes now have default administrative distance one, and behave like they should (they never get redistributed with redistribute connected command).
For example, with the router configuration ...
ip route 0.0.0.0 0.0.0.0 serial 0/0.1
ip route 18.104.22.168 255.0.0.0 172.16.0.4
... both routes have identical administrative distance:
POP#show ip route 0.0.0.0Routing entry for 0.0.0.0 0.0.0.0, supernet
Known via "static", >distance 1, metric 0 (connected), candidate default path
Routing Descriptor Blocks:
* directly connected, via Serial0/0.1
Route metric is 0, traffic share count is 1
POP#show ip route 188.8.131.52
Routing entry for 188.8.131.52 255.0.0.0
Known via "static", distance 1, metric 0
Routing Descriptor Blocks:
* 172.16.0.4
Route metric is 0, traffic share count is 1
Searching through Cisco's Bug toolkit turned up only a single relevant bug: CSCdi38232 (redistribute connected should not redistribute static route to OSPF), which was fixed in IOS release 10.2 and 10.3, that's probably also when they've fixed the administrative distance.


text:
Rare seahorses find love in the Thames
Evidence of a colony of rare seahorses has been discovered in the Thames, the Environment Agency said.
Hippocampus hippocampus, a short-snouted seahorse that grows up to 15cm (6in), is normally found in the Mediterranean and around the Canary Islands.
It has often been seen in coastal waters around Britain but had never been found so far upriver. The sighting of a juvenile specimen during a routine fisheries survey at Greenwich suggest there may be permanent populations in Britain and that the seahorses, which mate for life after elaborate courtship rituals, could be breeding in the Thames.
Emma Barton, a fisheries officer at the Environment Agency, said the sighting was a "really exciting discovery".


text:
See all our news
Canadians love our yogurts! Since 1971, Canadian yogurt consumption has increased from 471 g to 8.7 kg per person each year. From drinkable yogurts and tubes to probiotics and unique flavours, our nutritious innovative products have played a vital role in this tremendous growth.
Our company


text:
UIT Help Center
- Chat Live Chat
- Email email@example.com
- Submit a help form
- Call 713-743-1411
- Visit the Tech Commons
UIT Alert: UIT Alert UH Wireless Service
Current Status
Service Affecting Incident Resolution: UH Wireless service
Resolution Statement
Actions and Root CausesUH Wireless service disruptions occurring in several buildings on the UH campus were restored as of 11:00 AM today.
Corrective and Preventative MeasuresA DHCP server was restarted.
Affected Services
- UH Wireless network
Event Updates
ITAC is contacting the UH Wireless team to investigate this incident. The estimated time to repair is not available at this time.
Buildings reporting service disruptions are
518 - Calhoun Lofts Apartments
509 - MD Anderson Library, Technology Commons
540 - Law Library
556 - Settegast Residence Hall
557 - Bates Residence Hall
558 - Taub Residence Hall
555 - Law Residence Hall
ITAC will distribute an update after an assessment of the scope and impact is completed.


text: Author: pbiapprove Date: 2012-01-23 19:01:19 +0000 (Mon, 23 Jan 2012) New Revision: 15039 Modified: pbi/update/pbi-meta-9 Log: PBI-9 Meta-Update: QtCreator Modified: pbi/update/pbi-meta-9 =================================================================== --- pbi/update/pbi-meta-9 2012-01-23 18:52:10 UTC (rev 15038) +++ pbi/update/pbi-meta-9 2012-01-23 19:01:19 UTC (rev 15039) @@ -453,7 +453,7 @@ App=Qsstv;Communications;http://images.pbidir.com/progicons/qsstv.png;Johan Maes;http://users.telenet.be/on4qz/;GPL;Graphical;radio,sstv,osstv;Amateur Radio SSTV/FAX reception program for PC-BSD. SSTV decode and Version 5 supports FAX reception. Sstv_tx is a statically compiled version of QSSTV for transmission only.;; App=Qsvn;Development;http://images.pbidir.com/progicons/qsvn.png;Andreas Richter;http://www.anrichter.net/projects/qsvn/;GPL;Graphical;svn,subversion;QSvn is a GUI Subversion client for Linux, UNIX, Mac OS X and Windows. It is a real client not a GUI wrapper for the command line client from Subversion. QSvn uses a C++ Subversion wrapper developed by the Kdesvn Project. For cross plattform QSvn uses the Qt Framework from Trolltech.;; App=Qsynth;Audio;http://images.pbidir.com/progicons/qsynth.png;Qsynth Team;http://qsynth.sourceforge.net/;GPL;Graphical;audio,synthesizer;Qsynth is a fluidsynth GUI front-end application written in C++ around the Qt4 toolkit using Qt Designer. Eventually it may evolve into a softsynth management application allowing the user to control and manage a variety of command line softsynth but for the moment it wraps the excellent FluidSynth.;; -App=QtCreator;Development;http://images.pbidir.com/progicons/qtcreator.png;Qt;http://www.qtsoftware.com/products/developer-tools;GPL;Graphical;IDE,C++,Qt;Qt Creator is a new cross-platform integrated development environment (IDE) tailored to the needs of Qt developers. It includes: * An advanced C++ code editor * Integrated GUI layout and forms designer * Project and build management tools * Integrated, context-sensitive help system * Visual debugger * Rapid code navigation tools * Supports multiple platforms;; +App=QtCreator;Development;http://images.pbidir.com/progicons/qtcreator.png;Qt;http://qt.nokia.com/products/developer-tools;GPL;Graphical;IDE,C++,Qt;Qt Creator is a new cross-platform integrated development environment (IDE) tailored to the needs of Qt developers. It includes: * An advanced C++ code editor * Integrated GUI layout and forms designer * Project and build management tools * Integrated, context-sensitive help system * Visual debugger * Rapid code navigation tools * Supports multiple platforms;; App=Quake3;Games;http://images.pbidir.com/progicons/quake3.png;id Software;http://www.idsoftware.com/games/quake/quake3-arena/;GPL;Graphical;game,fps,quake;A multiplayer first-person shooter computer and video game released on December 2, 1999. The game was developed by id Software and featured music composed by Sonic Mayhem and Front Line Assembly. Quake III Arena is the third in the series and differs from previous games in the series by excluding a traditional single-player element and focusing on multi-player action. The single-player is instead played against computer controlled bots in a similar style to Unreal Tournament.;; App=Quake4 Demo;Games;http://images.pbidir.com/progicons/quake4.png;id Software;http://www.quake4game.com;Commercial;Graphical;game,fps,quake;This package contains Quake 4 for Linux (Demo version) by id Software.;; App=Quake4;Games;http://images.pbidir.com/progicons/quake4.png;id Software;http://www.quake4game.com;Commercial;Graphical;game,fps,quake;This package contains Quake 4 for Linux by id Software. In order to play this game, you need to add the data files that are available on the Quake 4 CD\'s or DVD.;;


text:
Zanji Student Application
Alright after a while of not training people I have decided to start training on a full scale. But only 5 Students will be accepted by me at ANY given time. My sempai Lysander has already been training people (and a fair warning to those students of his I will be tasking each of you with something int he near future.). I know this is somewhat pointless to tell you green horns because you won't dare listen no matter how many times your told. Do NOT VM me nor PM me on if I can train you because I will simply ignore you as I have been already.
Now in the past what I would do is set up a little "tournament" of sorts just to see what the hell you guys are capable of, and if you would be worth training. An example of people whom have partaken in the student tournies I would do are Izuna and Rag, and another former student of mine is Scary Yamato.
Now due to the day and age we are all in, I must say that you shouldn't expect to "reach" the degree they have or I have but I will do my best to make sure you get close, as that is my sensei duty.
Now to what I will and will not teach.........
Will Teach:
Basic 5 (2 at a time)
Lava, Ice, Dark, Storm, Sand, Wood: (2 at a time)
Hidden Clan Ability (Inuzuka, Aburame, Yamanaka, Nara): (1 at a time)
Taijutsu: (1 at a time)
Fuuin & Kin: (1 at a time but only if your permitted to learn it and I must have proof)
How to fight: (1 at a time but must have at LEAST 3 elements MASTERED)
Will NOT Teach:
I will not awaken your Sharingan
I will not teach you my customs
I will not teach you my Dry Ice
I will not permit you to sign the Dragon Contract
Now once 5 Students have been reached I will have this thread closed. So I will repeat, Do NOT PM me nor VM me to teach you any longer. Because to be quite honest I am getting sick and tired of being asked several hundred times.
Also a side note, I will only teach you up to your CURRENT rank at the start of the training so that I can train more students.


text:
Clash of Clans is a very beautiful game. It is a strategy game. In this game, you have to train a good number of troops to fight against the enemies and to save your own village. The actual aim should be to lead your clan to defeat the enemy and to touch the victory. Now when you play this game, the first thing that you have to maintain is to keep a sufficient amount of gems. To complete the game, or to continue the game, it is necessary that you must use some ways to get a free flow of the gems.
Now the easy and most reliable way to get the free flow of the gems you can use the Clash of Clans Cheats. Through these cheats, you can access, unlimited gems, gold, and Elixir. Now if you are a true fan of the Clash of Clans game, then you want to continue playing the game, and win at it. Now it depends on upon you how you want to continue the game because it is a clear fact that you need to use a source to play the game.
Clash of Clans Cheats must unlock all the possible resources to collect unlimited gems and gold. In this game, you have to defeat the enemy to win the game. And this can be possible when you apply all the possible ways to explore all the resources to gather all the necessary items to win the game. If you search, then you can read a huge number of reviews, which means a huge number of fans of the game use these cheats to play it smoothly and to win the game. Remember, your only aim should be to taste the victory.
Some key features of the Clash of Clans Cheats:
- The first and the most important feature of it is you can collect a huge number of gems by using it. And most importantly, all the gems are free. That means you can have it with free access.
- You can also collect a good amount of Gold and Elixir from using these cheats. In a word, these Cheats help you to collect all the essential items that are needed to continue the game. Even you can explore lots of important resources, which help you to acquire more advance steps while playing the game.
- It supports most of the operating systems in the mobiles. You don't need to worry about the updates. The Clash of Clans Hack – COC For Gems
update normally in a unique way. As it uses a proxy support, so there is no question of any kind of detection. And with the regular update, it is clear that no virus can affect it. So you can use it rapidly and safely.
So the above features clearly depict some true aspects regarding the use of the cheats. It is true that there are several other ways that you can use to play the game easily. But by using the cheats you can explore more opportunities to play the game very easily.


text:
DEPARTMENT OF HEALTH AND HUMAN SERVICES Public
Health Service Food
and Drug Administration Cardio-Renal
Advisory Committee Questions losartan January
6, 2003
Public Health Service
Food and Drug Administration
Cardio-Renal Advisory Committee
January 6, 2003
The Cardio-Renal Advisory Committee is asked to opine on the relative effects of an antihypertensive regimen containing losartan compared with a regimen containing atenolol, both administered once per day. Specific guidance is sought on the adequacy of the current program to support a claim of superior efficacy for losartan at reducing the incidence of the combined endpoints of cardiovascular mortality, MI and stroke, as well as guidance on how to describe any relevant differences in labeling. Additionally, guidance is sought regarding the relevance and appropriate description for an observed qualitative interaction between race and the effects of the two study drugs.
In the past, the Agency has told sponsors that a robust demonstration of a clinically relevant difference between two drugs, if done fairly, would be appropriate for inclusion in labeling. There are few examples of such trials being presented to the Agency and being incorporated into labeling, such that the current trial has some value as precedent.
1. The LIFE trial compares the effects of losartan and atenolol on cardiovascular outcomes. For a population like that studied in LIFE, what is known from external sources about the effects of beta-blockers (including atenolol) and angiotensin receptor blockers (ARBs) (including losartan) on the incidence of death, MI or stroke? Describe the basis for your position.
1.1. Cannot be determined.
1.2. Both are superior to placebo and equivalent to each other.
1.3. One or both are superior to placebo, but not equivalent to each other (specify ranking).
1.4. Both are equivalent to placebo.
2. Regarding the LIFE trial data in the overall population studied, describe the overall difference between patients receiving the losartan-based regimen and the atenolol-based regimen in the trial.
2.1. Was superiority of the losartan-based regimen demonstrated:
2.1.1. for the primary endpoint?
2.1.2. each of the three components of the primary endpoint?
2.2. Was the comparison between the two regimens a fair one, as discussed in the ICH E10 Guidance? For example, were appropriate doses of both medications used?
2.3. Could the observed differences in clinical outcomes be the result of differences in blood pressure control? Recall that the two groups had 'similar' but not identical reductions in blood pressure measured at trough, but that limited data are available to compare blood pressures at other time points.
3. Are the results of LIFE alone an adequate basis for approval of losartan to reduce the combination of cardiovascular mortality, MI and stroke?
4. If not, are the results of LIFE, combined with prior expectations derived from the other sources you considered in question one an adequate basis for approval of losartan to reduce the combination of cardiovascular mortality, MI and stroke?
5. Do you recommend approval of losartan as having demonstrated superior efficacy when compared with atenolol in the population studied in LIFE to reduce the incidence of the combination of cardiovascular mortality, MI and stroke? If so, how should the FDA think about describing this trial (and others like it) in labeling?
5.1. Narrowly, as comparisons between two drugs of different classes in a specific population of hypertensive patients, to be described as extensions of antihypertensive efficacy?
5.2. More broadly, as comparisons between drugs of different classes in individuals identified as being 'high-risk', to be described as novel indications? If so, how should the findings of these trials be included in the approved labeling for losartan?
5.2.1. As demonstrating superiority of losartan over atenolol in the population?
5.2.2. As demonstrating superiority of losartan over placebo in the population?
6. The sponsor has presented analyses looking at the comparative effects of the two drugs in a number of demographic subgroups. None of these analyses were allocated alpha as part of the statistical plan. Do any of these analyses meet the standard for robustness of clinical data sufficient to support the description of the effects of losartan in the population? If so, please identify that population or populations and the basis for your conclusion.
6.1. Patients with left ventricular hypertrophy identified by ECG criteria
6.2. Women
6.3. Patients with isolated systolic hypertension
6.4. Patients with diabetes
7. The FDA has identified an association between atenolol use, atrial fibrillation and stroke. Does this analysis, combined with other available data meet the standard for robustness of clinical data sufficient to support a description of these effects? If so, where?
8. You have heard a discussion of qualitative and quantitative interactions among subgroups. For one relevant subgroup, African-Americans in the U.S., atenolol is apparently superior to losartan in its effects on the primary endpoint. No biologic rationale for this apparent qualitative interaction with race has been identified by the FDA or the sponsor.
8.1. Does the lack of this rationale matter to you?
8.2. Are there other data you feel illuminate the observed differences? Do you find this outcome surprising?
8.3. Do you find the difference compelling? If so, which of the following describe the relationship of losartan (L), atenolol (A), and an imputed placebo (IP) with regard to their effects on the primary endpoint in African-Americans:
8.3.4. Other ordering?
8.3.5. Cannot tell?
8.4. How should the finding be described in labeling? Please provide specific language if possible.
8.4.1. Contraindication to the use of losartan in African-Americans if the goal is the reduction in death etc.?
8.4.2. Warning or Precaution that this interaction exists.
8.4.3. Description in the Clinical Trials section.
8.4.4. No description of this finding in labeling.


text:
With any software, there are times when you need assistance to make full use of it.
Here at DataNucleus we want you to make the best of the software that we provide. For that
reason we provide commercial services.
The DataNucleus experts are available for
Consulting for cases
where you need somebody intrinsically familiar with the DataNucleus system available
to resolve any particular implementation issues.
Similarly, if your company would like to build up your own experience in DataNucleus and
would like a kick start for this process the DataNucleus experts are available to provide


text:
Minneapolis Real Estate
WE Team is your
one stop shop for all your real estate needs. We pride
ourselves with our extensive experience and knowledge of the
Minneapolis St Paul real estate market. Whether you are
looking to sell or buy a home in the Twin Cities metro, our
team's commitment goes above and beyond. We take the stress
out of your real estate needs, and we work for you to help
you make the best home buying and selling decisions
Best Minneapolis
Real Estate Team
Search for Homes in Minneapolis, St. Paul & the Surrounding
Twin City Area
WE Team
Pearl S. Buck once said that "The young do not know enough to be prudent, and therefore they attempt the impossible, and achieve it, generation after generation". This Statement could not be more true about Scott Wollmering and his world leading team of real estate professionals known
as the "We Team"!
Scott Wollmering is a long time Minnesotan! Scott cut his teeth in business in the Twin Cities in 1994 by opening three Christian daycare centers in the southern Twin Cities. It was there that Scott first learned the importance of superior customer service. In 1998 Scott left his daycare centers in the qualified hands of his on-site directors and focused 100% on real estate. Scott, who is the father of three beautiful children, realized very quickly that he could not keep up with the volume of business he was doing on his own. It was at that time in 2000 that "THE WE TEAM" was developed.
When Scott set out to create the WE Team, his strategy was simple, "what we would want from a REALTOR® if we were the client". From that simple philosophy, Scott created a team of dedicated professionals who take pride in that kind of service.
Since that time the WE Team has been ranked in the top ten teams consistently. In 2004, 2005 and 2006 the WE Team was ranked either #1 or #2 in the state with two of those years being ranked in the top 50 in the United States and #98 in the World.
a. In addition to Wollmering, the WE Team includes approximately six fulltime agents, a fulltime listings coordinator, fulltime marketing manager, as well as a runner and other office support staff. Scott's Minneapolis real estate business personally focuses primarily south of the river. However, "The We Team" has top agents covering every area of the Minneapolis St Paul, the Twin Cities metro areas. This innovative group of real estate professionals is leading their profession by continuing to offer the personal, honest, and friendly service of yesterday, with the high speed, high tech services of tomorrow. The We Team motto is simple, continually strive to better understand what clients want and then make it our top priority to deliver.
Site Map Blog
Listen to Scott
Saturdays, 10-11 AM on AM 1130
Real Estate Show
View Preferred Providers
WE Team Realtors Minneapolis St Paul, Minnesota © 2017
Net Eagles Web Development


text:
FLORENCE, S.C. – Wilson High School and Hannah-Pamplico High School took top honors at the recent Pee Dee Regional High School Mathematics Tournament. The tournament, sponsored by the Pee Dee Education Center and Francis Marion University, was held in the university's McNair Science Building auditorium.
The 27th-annual event featured 244 students from 15 area schools.
Participating schools were divided into Division I and Division II schools. Schools with A and AA athletic classifications were considered Division I, while AAA and AAAA athletic classifications were considered Division II.
All students participated in a one-hour written competition during the morning portion of the tournament. Bella Wang and Robert Wells, both of Wilson High School, recorded the highest individual result, correctly answering 16 of 18 problems. Megan Hyman of Hannah-Pamplico High School was third and Maegan Rogers of Latta High School and David Braddy of Dillon High School tied for fourth. Braddy was second in last year's written competition.
The top four individual test scores from each school were combined to create a team score. The four schools in each division with the highest team score qualified for the afternoon finals.
The finals consisted of four individuals from each qualifying school answering questions flashed onto an overhead screen. Points were awarded to the first, second, and third persons who answered correctly.
In Division I, Hannah-Pamplico won its fifth team title, but its first since 1996, by defeating Johnsonville and Mullins High School (tied for second) and Latta High School (fourth). The four individuals who represented Hannah-Pamplico in the finals were Lance Butler, Hyman, Kelvin Pompey, and Elliot Turner. Carolyn Riddick is the Hannah-Pamplico math team adviser.
Among Division II schools, Wilson captured its first team title since the inaugural competition in 1979. Dillon High School placed second, followed by Marion High School and Hartsville High School. Representing Wilson in the afternoon finals were Ming Li, Samir Panvelker, Wang, and Wells. Dorothy Fleck serves as the adviser for the Wilson math team.


text:
TRURO – A Truro man convicted of threatening to "wound, maim, disfigure or endanger the life" of another man was sentenced in provincial court on Friday to 46 months in jail.
William Joseph O'Brien (aka Henwood), 37, of 282 James St., was also convicted of assaulting another man and uttering threats to five other individuals, possessing marijuana and possessing a weapon (garden shears) for a purpose dangerous to the public peace.
O'Brien/Henwood was given credit for 23 months time served in remand while awaiting sentencing.
He was further banned from possessing firearms for 10 years and was given a lifetime ban on possessing prohibited weapons.


text:
Player InformationFlames Home > Men's Tennis Home > Men's Tennis Roster > Roster Detail
Stan VaughanClass: Junior
Height: 6-3
Weight: 190
Previous School:
Hometown: Golden, Colo.
2011-2012 (So.):
• Notched four singles victories during the fall tournament slate, including a pair of wins at the UNCG Fall Invite
• Recorded a 4-2 mark in doubles play
• Reached the doubles finals of Draw A with partner Siim Tuus at the UNCG Fall Invite, posting an overall mark of 3-1 during the tournament
• Won his lone doubles match during the spring
2010-11 (Fr.):
• Recorded 3-3 singles mark during fall tournaments and a 5-1 record in doubles play
• 7-5 record in spring dual matches, with all but one taking place in the No. 6 position
• Posted a four-match win streak.
• Once named Denver Post Student-Athlete of the Week
• Ranked in the top 4 in Colorado in 18s.
• Son of Mike and Stefania Vaughan
• Birthday is Feb. 28
• Majoring in international business.


text:
Perioperative Treatment of Resectable Liver Metastases (PERIMAX)
This study has been withdrawn prior to enrollment.
(insufficient recruitment)
University of Regensburg
University of Halle Medical Faculty
Information provided by (Responsible Party):
Hans J Schlitt, Prof. MD, University of Regensburg
ClinicalTrials.gov Identifier:
First received: February 16, 2012
Last updated: May 28, 2013
Last verified: May 2013
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
Study was withdrawn before participants were enrolled.
|Study Status:
|This study has been withdrawn prior to enrollment.
|Study Completion Date:
|May 2013
|Primary Completion Date:
|May 2013 (Final data collection date for primary outcome measure)


text:
Out & About - IMAX Theatre
Out & About is an occasional series of stories that highlight the best Charlotte has to offer in arts and culture, shopping and dining, entertainment and sports.
By Dana Robles
A visit to the Charlotte Observer IMAX® Dome Theatre at Discovery Place Uptown is perfect for those in search of documentary and short subject films that give the sensation of being right in the middle of the action.
The theatre boasts the largest screen in the North Carolina/South Carolina region and provides an intense visual and audio experience that can't be compared to any regular screen experience. Film topics range from the animal kingdom to real life adventures and everything in between. Disaster Response Rescue, Jane Goodall's Wild Chimpanzees and Greece: Secrets of the Past are just a few of the many films that have been showcased at the theatre, along with pop culture favorites including Pink Floyd's The Wall.
The IMAX theatre is located at 301 N. Tryon St., in Uptown Charlotte at Discovery Place-less than a 10 minute drive from Queens. Ticket prices are $10 for adults and $9 for seniors and children (2-13). Film times vary, so check the website for current showings, times, directions and parking instructions.
Imax Fun Facts:
• Film travels horizontally through the projector at 24 frames per second. That means over 5.5 feet of film moves through the projector every second. A 45-minute feature film is over 2.5 miles long and weighs about 250 pounds.
• To keep the high-powered projector lamp from exploding, 10 gallons of deionized distilled water is passed through the lamp's electrodes every minute to cool the 1,700 degree surface.


text:
Swissvale couple's home is collection of oddities
When Velda Von Minx first met the mysterious Mr. Arm, it wasn't love at first sight.
But when he told her he had "a freezer full of dead squirrels," and invited her to help him cut up and stuff them -- well, that piqued her interest.
A romance for the ages• Perhaps. They remain, however, perhaps the least bizarre inhabitants of Trundle Manor, the couple's Swissvale abode. The stuffed squirrels are there, too, perched atop a cabinet full of various toothy animal skulls, creatures pickled in jars, rusty antique meat cleavers, and other eye-catching oddities. One of the squirrels wears a wedding dress.
"I made the clothes," says the corset-clad Von Minx, who -- as Rachel Rech, 22 -- studied costume design in school.
Mr. Arm, also known as Anton Raphael Miriello, 28, is the taxidermist -- a dying art that he largely has had to teach himself. Despite the slicked-back hair and handlebar mustache, Miriello comes across more as an affable, eccentric collector than shady sideshow impresario.
"We can't really say what we collect," he says. "I always imagined this as a Roadside America-type attraction."
Trundle Manor, atop a steep hill in Swissvale, is a kind of Gothic fantasia of old-timey circus sideshow oddities, black-and-white horror-movie props, humorously morbid taxidermy -- like the Fiji mermaid, an infamous hoax -- and assorted artifacts that seem like they crawled out of a Tom Waits song, or the Addams Family's attic.
Its most recent claim to fame was being featured on an episode of MTV's "Cribs," which must have run out of rappers and rockers' interior-design atrocities.
The best word for it is German -- wunderkammer , a "wonder-room" or cabinet of curiousities. Before museums existed, it was fashionable for 17th-century German aristocrats to impress their friends by showing off their collections of archeological artifacts, religious relics, exotic animal specimens and so on. Many of the pieces were fakes.
It's hard to say what the weirdest thing is at Trundle Manor, but the singing tumor is probably up there.
"It's from the belly of a belly dancer," says Miriello. "She brought it to us in a Tupperware container."
Now, Olivia's Tumor sits inside a giant jar, attached to an antique-looking music box, built from scratch by Miriello, playing music.
Trundle Manor's panoply of stuffed bears -- the once-living, eat-you-for-lunch kind -- blend into the background after a while. Things that stick out, though, include a creature that's part grouse, part raccoon, part alligator. For good measure, the monster is a puppeteer, with a squirrel as its marionette.
"We don't kill things -- we just collect them," says Miriello. "Bears seem to find us. ... We know a guy who really doesn't like squirrels. Old, crappy taxidermy -- when it's falling apart, we love it more. I feel like I'm saving the dead, sort of."
Miriello grew up as the child of artists, collectors and tinkerers. His parents run the New Guild Studio in Braddock, which specializes in liturgical art, where he occasionally works. He's worked as a builder of railroad miniatures and at a costume store. Some of his collections, like the tiny frogs in jars, began as a child.
"My dad collects Machine Age and Art Deco," Miriello says. "He said, 'You collect nothing but junk, but you display it so perfectly.'"
Truly, there's no wasted space in Trundle Manor's living room full of dead things. Every spot on the blood-red walls has something weird on it, from strange animal skulls -- like the Muntjac, a tiny African deer with fangs -- to rusty scythes and a looming, mysterious machine in the corner that transforms into a workbench.
Uncle Trundle sits, watching it all through empty eye sockets. Miriello crafted this tuxedo-clad corpse as a way to keep people from sitting on a delicate 100-year-old chair.
In the garage out back are "Trixy" and "The Purple Tentacle," Mr. Arm and Von Minx's preferred modes of transportation.
Trixy, the more impressive of the two vehicles, was once the shell of a '52 Dodge truck that Miriello got when he was 17. He rebuilt it as a monstrous black hot rod, with exposed engine block, cow catcher on the front, and vertical flamethrowers behind the cab. Inside, he custom-built the dashboard out of wood, with functional levers and diodes that look straight out of a mad scientist's laboratory in a horror flick from the '50s.
Although it's not large, Trundle Manor often hosts parties and meetings of unusual groups. The Steampunk Guild of Pittsburgh -- which creates fanciful science-fiction technology with Victorian-era style and machinery -- is a particular favorite.
One can only speculate at the amount of dares proposed by local kids on Halloween -- who's not afraid to trick-or-treat at Trundle Manor• The brave ones are rewarded, though.
"They know we give out the big candy bars," Rech says.
There's no charge for a tour -- arranged by appointment only -- of Trundle Manor at the moment.
"We ask for donations, but don't push it," Miriello says. "We also take booze, dead things, et cetera."
Photo Galleries
Trundle Manor
What: Tours
Admission: Free, but donations are accepted. By appointment only
Where: Swissvale
Details: 412-916-5544 or www.trundlemanor.com


text:
Zend Framework encourages the use of autoloading, and even initializes it by default in
Zend_Application. Hopefully this tutorial provides you with the
information you need to use
Zend_Loader_Autoloader to its best
advantage, as well as extend its capabilities by attaching custom autoloaders or resource
For more information on its usage, read the Zend_Loader_Autoloader and Zend_Loader_Autoloader_Resource manual pages.
Copyright © 2005-2011 Zend Technologies Inc (compiled by mikaelkael with ZFDocumentor - SVN 24426).


text:
SoJO 7@7 Countdown For Tuesday, April 10 [VIDEO]
Carly Rae Jepsen entered the countdown tonight, but how far did she get? Did Gotye finally upset One Direction? Keep reading for a list of South Jersey's seven hottest songs!
7. 'We Are Young' by Fun.
6. 'Call Me Maybe' by Carly Rae Jepsen
Subscribe to SoJO 104.9 FM on
5. 'Lullaby' by Nickelback
4. 'A** Back Home' by Gym Class Hereos
3. 'Eyes Open' by Taylor Swift
2. 'Somebody That I Used To Know' by Gotye
1. 'What Makes You Beautiful' by One Direction


text:
The NSW Parliament has been rocked by news that its computers may have been used to access child pornography.
NSW independent MP and Speaker Richard Torbay is seeking legal advice after a report into internet usage on parliament computers revealed nine websites were viewed which may have contained child pornography.
He told Parliament on Thursday the websites contained "sexually explicit images of young people, whose precise age is reportedly difficult to determine". He said no further comment would be made "so as to not jeopardise any investigations that may ensue".
Mr Torbay commissioned Ernst & Young earlier this year to compile a report on Parliament's internet filtering system. The report, which has been tabled in parliament, revealed 35 adult-related websites had been visited in the 10 months to September 6 this year.
Ports minister Paul McLeay resigned his post in September after admitting to browsing gambling and adult websites. But there is no suggestion in the report that he accessed child pornography sites.
Mr Torbay released the report on Parliament's last sitting day of the year. The state election will be held on March 26.
The Australian Financial Review


text:
This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
Changes in the developmental or metabolic state of plastids can trigger profound changes in the transcript profiles of nuclear genes. Many nuclear transcription factors were shown to be controlled by signals generated in the organelles. In addition to the many different compounds for which an involvement in retrograde signaling is discussed, accumulating evidence suggests a role for proteins in plastid-to-nucleus communication. These proteins might be sequestered in the plastids before they act as transcriptional regulators in the nucleus. Indeed, several proteins exhibiting a dual localization in the plastids and the nucleus are promising candidates for such a direct signal transduction involving regulatory protein storage in the plastids. Among such proteins, the nuclear transcription factor WHIRLY1 stands out as being the only protein for which an export from plastids and translocation to the nucleus has been experimentally demonstrated. Other proteins, however, strongly support the notion that this pathway might be more common than currently believed.
Plastids are the characteristic organelles of plant cells. They are best known for their photosynthetic function and as factories producing numerous compounds for metabolism. In higher plants chloroplasts develop from undifferentiated proplastids in meristematic cells or from etioplasts, which might differentiate from proplastids when plants germinate in darkness. The characteristic structural and functional plasticity of the plastids depends on the tissue, the developmental age and the environmental situation the plant is experiencing. In other words, the differentiation state of plastids is the result of diverse endogenous and exogenous influences/factors. Due to their sessile way of life, plants need efficient receptors for diverse abiotic and biotic stimuli to respond continuously to changes in the environment.
Chloroplasts play a central role in sensing the environmental situation and executing adaptive responses of plants [
In this review the role of proteins in chloroplast-to-nucleus communication is discussed. Increasing evidence indicates that chloroplasts indeed possess numerous proteins, which have also been detected in the nucleus and/or the cytoplasm. Generally, one needs to distinguish between proteins that are sequestered on the cytoplasmic face of the chloroplast envelope membrane and are released upon certain triggers by specific endopeptidases and proteins that are sequestered in the stroma of chloroplasts. Examples for the first group have been discussed before [
The original dogma that each polypeptide chain fulfils only one function has been replaced over the last two decades by the notion that many—if not most—proteins are bi- or even multifunctional. One of the reasons why some isoforms of many enzymes have not been discovered until fairly recently is that the secondary functions are exerted in other compartments than the initially attributed primary function [
Besides the dual targeting of proteins, which are synthesized
In 1998 Small and coworkers postulated that the multitude of shared activities connected to the expression and maintenance of the genetic information located in the nucleus and the organelles should entail the occurrence of a larger set of proteins shared by two or all three DNA containing compartments [
Many dual targeting events initially escaped the attention of researchers because the isoforms of the corresponding proteins were described under different names and often in different species or were mistaken as paralogs. Some of the earliest known examples are the plastid RNA binding proteins cp29 and cp31 [
In most studies on dual or multiple targeting the molecular masses of the proteins in different compartments are unknown [
In contrast, other proteins such as WHIRLY1 have the same molecular mass in two different compartments. Upon import into the plastids, WHIRLY1 is processed by cleavage of an
Several proteins were suggested to be located in plastids and the nucleus, respectively, on the basis of bioinformatic predictions [
A subset of the dually targeted proteins described above and listed in
In the current literature, the discussion on plastid-to-nucleus retrograde signaling focuses strongly on light-induced coordination of gene expression upon de-etiolation. So far, there is no evidence that any of the dually targeted proteins is involved in the extensive expression changes in the nucleus following this drastic change in the plant's environment. Rather, the above-mentioned examples point to responses to plastid-perceived stresses such as pathogen infection.
Plastid gene expression is regulated at different levels involving transcription initiation, splicing, editing and processing of RNAs and also translation. Most of the plastid/nucleus targeted proteins are involved in one or the other step of this complex process. An intimate involvement of RNA-binding proteins in retrograde signaling has received support by the recent finding of an unprecedented link between RNA-editing and plastid-to-nucleus signaling [
Maize transposon mutants impaired in WHIRLY1 were reported to have a bleached phenotype [
Several of the dually targeted proteins have the same molecular mass in plastids and the nucleus. The first hint that the nuclear isoforms of plastid/nucleus targeted proteins do not arise by twin targeting (
Recently, an experimental approach provided unambiguous evidence for the existence of similar retrograde translocation pathways in plastids. For this, a recombinant tagged WHIRLY1 protein was expressed from a transgene that was integrated into the plastid genome [
Given the fact that most cellular mechanisms of fundamental significance are conserved among eukaryotic cells and even between eukaryotes and prokaryotes and that specific peptide and protein export machineries exist in prokaryotes as well as in mitochondria of yeast and mammalian cells, it comes as no surprise that the existence of a similar export across the chloroplast envelope membrane has been proposed already some time ago [
So far, the mechanism(s) by which proteins can be released from plastids remain elusive, but a number of possibilities have been brought up in the past, that will be summarized here.
Stromules are tubular extensions by individual plastids that are filled with stroma [
Stromule formation has been shown to be dependent of tissue and cell type [
Physically tight membrane contact sites (MCS's) between the plastid membranes and the ER membranes [
At certain stages of chloroplast development, ER cisternae were found to form a sheath around plastids and the membranes even became continuous with the outer envelope membrane of plastids [
In yeast mitochondria, peptide transport is mediated by a member of the ATP-binding cassette (ABC) transporter family, MDL1 [
Protein secretion is a known phenomenon in bacteria that has actually been conserved in the chloroplasts. The general secretory (SEC) pathway and the twin-arginine translocation (TAT) pathway of bacteria [
Most instances of retrograde translocation from the plastid and mitochondrial compartments—in plants likewise as in yeast or mammalian cells—are connected to stress or pathogen attack (
Several proteins were described to be dually located in plastids and the nucleus. For one of them—WHIRLY1—the transfer from chloroplasts to the nucleus has been experimentally demonstrated employing transplastomic tobacco plants synthesizing the tagged protein inside the organelle. The transplastomic plants enable to study the export of the protein without interference with the import of proteins. Several scenarios for protein exports from plastids are possible. If the export is stimulated by stress related factors such as reactive oxygen species, the membrane might get leaky. ER-chloroplast contacts could be involved in the transfer of proteins from plastids to the nucleus. Tagged proteins synthesized in the plastid will allow investigating the pathway from plastids to the nucleus.
Although there is yet no information on development related changes in the dynamic abundances of dual targeted regulatory proteins in the different compartments, it is likely that plastids of different developmental stages have specific sets of regulatory proteins destined for the nucleus reflecting their functional situation within a given tissue and at a specific developmental stage. Proteome analyses with purified plastids and nuclei at different stages of plant development are required to address this question.
Work on plastid-nucleus dual targeting of proteins is supported by the Research Council of Norway (YFF project 180662/V40 to K. Krause) and the Deutsche Forschungsgemeinschaft (Kr1350/9-1 to K. Krupinska).
Chloroplasts are involved in the perception of intrinsic triggers controlling plant development and external cues and stresses from the abiotic and the biotic environment. A novel signaling pathway involving chloroplast located proteins that might be translocated to the nucleus in response to the diverse stimuli perceived by chloroplasts (see text) is depicted here. Whirly1 is the only protein for which a
Selected mechanisms of protein translocation from chloroplasts to the nucleus. (
List of proteins that are targeted to the plastids (p) and the nucleus (n).
|First described
|Protein name(s)
|Protein function
|Release from plastids
|cp29B (p)
|RNA-binding protein transcriptional repressor
|not investigated
|cp31A (p)
|RNA-binding protein telomere-binding
|not investigated
|MFP1 (n)
|matrix attachment region binding nucleoid associated protein
|not investigated
|GSBF1 (n)
|transcription factor nucleoid associated protein
|possible [
|DHFR (p + n)
|dihydrofolate reductase/thymidylate synthase
|no [
|LEM1 (p + n)
|unknown (homologous to plastid ribosomal protein PRPS9)
|not investigated
|WHIRLY1 (p)
|DNA + RNA binding; DNA maintenance transcriptional activator; telomere-binding
|yes [
|CDT1 (p)
|plastid division (interaction with Arc6) DNA replication
|not investigated
|ATXR5 (p + n)
|control of cell cycle and DNA replication in the nucleus; plastid function unknown
|not investigated
|NtWIN4 (p)
|induction of hypersensitive cell death transcriptional repressor
|no [
|pTAC12 (p)
|nucleoid associated protein phytochrome signalling
|not investigated
|At2g44940 (p + n)
|transcription factor with AP2 DNA binding motif
|not investigated
|IPT3 (p + n)
|cytokinin biosynthesis in plastids; nuclear function unknown
|no [
|NRIP1 (p + n)
|rhodanese sulfur transferase; immune receptor recognition; plastid function unknown
|possible [
|SIB1, SIB2 (p + n)
|proteins binding to Sigma factor1 of plastid encoded RNA-polymerase
|not investigated
|ANAC102 (p + n)
|NAC transcription factor
|not investigated


text:
The Crucible
by Arthur Miller
Richard Armitage stars in Arthur Miller's classic American drama brought vividly to life in this visceral new production.
I cannot sleep for dreaming...
Richard Armitage stars in Arthur Miller's classic American drama brought vividly to life in this visceral new production by internationally acclaimed director Yaël Farber.
In a small tight-knit community, personal grievances collide with lust and superstition, fuelling widespread hysteria. Miller's timeless parable attacks the evils of mindless persecution and the terrifying power of false accusations.
Richard Armitage's film and TV credits include The Hobbit trilogy, Captain America: The First Avenger and Spooks. Theatre includes The Duchess of Malfi and Macbeth for the RSC.
Yaël Farber is a multiple award-winning director and playwright. Her production of Mies Julie won a string of international awards at the 2012 Edinburgh Festival, was named one of the Top Ten Productions of 2012 by The New York Times, and Top five Productions of 2012 by The Guardian.
A production of electrifying intensity
Daily Telegraph
An extraordinary production
The Guardian
The Independent
Miller's parable of persecution at its most powerful and enthralling
The Times
This devastating and absorbing Arthur Miller revival is a triumph
Evening Standard
It is operatic, it is immense
Time Out
Captured live at The Old Vic, London, in September 2014.
Lead image © Jay Brooks
Production photography © Johan Persson
Available with English language Captions by Stagetext.
Available Formats
Rent for 48 hours
Rented productions are made available in your library for 30 days with 48 hours to complete viewing from the first time you begin playback. You can watch Rentals when online directly through your browser or on your iPhone, iPad or iPod touch.
Purchased productions are yours to keep forever, and can be watched online through your browser or enjoyed on one of our supported devices. Standard Definition purchases are normal broadcast quality, meaning smaller file size and quicker downloads when compared to a HD purchase.
Buy HD
Like Standard Definition purchases, High Definition productions are yours to keep forever, and can be watched online through your browser or enjoyed on one of our supported devices. High Definition purchases are the highest quality available and perfect for customers with HD televisions, monitors or Retina Displays.
Customer Comments
No comments have been posted. Be the first!
Login to your account to post a comment.
Related Productions and Pages
Interview with Richard Armitage
DigitalTheatre.com presents an exclusive interview with actor Richard Armitage filmed live on stage at The Old Vic.Read more
Lesley Manville stars in Richard Eyre's Olivier Award-winning revival of Ibsen's masterpiece.Read more
True West
A modern classic by one of America's most renowned living playwrights, exposing the cracks in the American Dream.Read more
All My Sons
Howard Davies' acclaimed production of Arthur Miller's classic 20th century drama with David Suchet and Zoë Wanamaker.Read more


text:
After the close of evidence at the High Court on Friday, Mr Justice Grigson injured his back and will not sit in court until he recovers.
No date has been given for his ruling, which will follow final submissions in writing from both sides in the dispute.
Oxford University wants to extend an existing 35-metre "no harassment" zone around its research laboratory.
It is claimed that nearly 98% of the new £18m facility's work would involve rodents, the remainder being amphibians, fish, and primates.
The university says it is not seeking to curb peaceful protest and has offered to provide a demonstration area immediately opposite its South Parks Road site.
Work on the construction of the laboratory stopped on 13 July because contractors faced harassment and intimidation from parts of the animal rights movement, said solicitor-advocate Timothy Lawson-Cruttenden.
Pressing for the injunction against 10 named defendants, Mr Lawson-Cruttenden said: "Our case is that we are being harassed or we anticipate that we may be harassed by the defendants."
'Protected persons'
The 10 are: Mel Broughton, John Curtin, Robert Cogswell, Speak Campaigns, Stop Primate Experimentation at Cambridge, Stop Huntingdon Animal Cruelty, Oxford Animal Rights Group, People Against Cruelty to Animals - West Midlands, West Midlands Animal Action and Animal Liberation Front.
During the hearing, proceedings were discontinued against Mr Broughton and Mr Cogswell after they offered legal undertakings not to harass any of the "protected persons" under the order.
The defendants are contesting the injunction under the 1997 Protection from Harassment Act on the basis that there is no evidence that they are acting unlawfully.
Oxford had become the new focus for animal rights groups after plans for a multi-million-pound laboratory at Cambridge were abandoned earlier this year because of the excessive costs of protecting staff.


text:
[Date Index]
[Thread Index]
[Author Index]
Re: Help with Importing of FITS files
gorskil3 at aol.com (Larry Gorski) wrote in message news:<ag6f0a$bov$1 at smc.vnet.net>...
> Hello. I just purchased the version 4.2 upgrade. I'm trying to
> import .fit files but the function Import["filename.fit","FITS"]
> returns a list and not a graphic. Any ideas as to what I am not doing
> correctly are appreciated.
> Thanks
> Larry
The Import command returns a list containing both the header
information and the image data. To see the image, you need to strip
the header and plot the data portion of the file.
See http://www.wolfram.com/products/mathematica//newin42/import.html
for an example. The options for FITS import are documented in the
Further Examples section of the import documentation in the help
Lars Hohmuth
Wolfram Research, Inc.


text:
Today, I went to my Calculus lecture, one of a class of 200 people. As I looked down I noticed that a guy a few rows in front of me was on Facebook. When I took a closer look, I noticed he was viewing my profile. He stalked the profile for a full 45 minutes. I have never met this guy in my life. FML
Consolation prizeYour FML was denied. We had to at least give you a badge to cheer you up a bit.100%
50 favoritesLove knows no boundaries. You've already added 50 FMLs to your favourites list!100%
The thumb strikes backYou have left your thumbprint on 2500 comments.0%
The return of the thumbYou have thumbed 5000 comments.0%
Keen reader – Level: student ninjaYou have voted for 15% of the entire collection of FMLs to date.0%
Keen reader – Level: master ninjaYou have voted for 50% of the entire collection of FMLs to date.0%
Keen reader – Level: godlike ninjaYou have voted for 100% of the entire collection of FMLs to date.0%
One more and it's business timeYou've received 68 Hugs on your profile. Kinky.0%
Today, I was running the track at my school. My crush of two years was running in front of me, so I decided to catch up and finally talk to her. When I caught up, the only thing I could think to say was, "What's your name?" even though I already knew. She replied, "Natalie". Her name is Melissa. FML
Today, I realized I've been playing too much Call of Duty. I started screaming, "Spawn, bitch! Spawn!" at my microwavable pizza while it was in the microwave. FML
Today, my boyfriend ditched me, saying he had some important things to do. When I checked on him a while later, I found out what was so "important". A game called Robot Unicorn Attack. FML
Today, while I was substitute teaching a middle school class, a boy, named Chris, refused to get in the boy's line for the bathroom. After I had said, "Chris, what makes you think you're a girl?" in a very loud voice, one of the other students said "She is a girl." I've scarred a child for life. FML


text:
On-air Talent
Michael Irvin
Prior to every Thursday Night Football game on CBS and NFL Network, Hall of Fame wide receiver Michael Irvin is an analyst on the NFL Total Access Kickoff pregame show on NFL Network, providing insight and expert commentary on all of the storylines heading into the night's matchup. Irvin joins host Rich Eisen and analysts Marshall Faulk and Steve Mariucci on the show. Additionally, Irvin appears on the Mazda Postgame Show with Eisen, Faulk, Mariucci and Deion Sanders.
On NFL Sundays, Irvin can be seen on NFL Network's Emmy-nominated NFL GameDay Morning, joining host Eisen and fellow analysts Mariucci, Faulk and Kurt Warner to discuss the upcoming games four hours prior to kickoff.
On NFL Sunday nights, Irvin joins Falk, Sanders and host Chris Rose on NFL GameDay Final to provide the final word on all of the day's action.
Irvin is a frequent contributing analyst to other NFL Network programming, including NFL Total Access.
Prior to joining NFL Network as a full-time analyst, Irvin served as a guest analyst on the network's coverage of the Pro Football Hall of Fame Induction ceremony in 2008 and 2009. Previously, Irvin served as an NFL analyst for ESPN from 2003-2007.
In 2009, Irvin appeared as a contestant on ABC's ninth season of Dancing with the Stars.
A 2007 Pro Football Hall of Fame inductee, Irvin spent his entire 10-year NFL career with the Dallas Cowboys where he won three Super Bowl rings in 1993, 1994 and 1996. His 750 receptions for 11,904 yards and 65 touchdowns still stand as tops in Dallas' franchise records in all three categories. In eight of the 10 seasons Irvin starred with the Cowboys, he led the team in pass receptions, which is one of 13 individual best marks held by the 'Playmaker' in the Cowboys' record books.
Irvin was the 11th overall selection by the Cowboys in the 1988 NFL Draft following a stellar career with the University of Miami where he still holds the record for career touchdown receptions (26) and most touchdown receptions in a season with 11 catches in 1986 after leading the Hurricanes to their second of five National Championships in 1987.
Other Links
- Kay Adams
- Brian Baldinger
- Judy Battista
- Brian Billick
- Taylor Bisciotti
- Tiffany Blackmon
- Kyle Brandt
- Bucky Brooks
- Nate Burleson
- David Carr
- Charley Casserly
- Jeffri Chadiha
- Patrick Claybon
- Erin Coscarelli
- Stacey Dales
- Dave Dameshek
- Charles Davis
- Terrell Davis
- Rich Eisen
- Heath Evans
- Michael Fabiano
- Marshall Faulk
- Alex Flanagan
- Cynthia Frelund
- Mike Garafolo
- Akbar Gbajabiamila
- Scott Hanson
- Elliot Harrison
- Dan Hellie
- Michael Irvin
- Marc Istook
- Daniel Jeremiah
- Kimberly Jones
- Maurice Jones-Drew
- Aditi Kinkhabwala
- James Koh
- Andrea Kremer
- Mark Kriegel
- Rhett Lewis
- Steve Mariucci
- Mike Mayock
- Willie McGinest
- Kyle Montgomery
- Randy Moss
- Shaun O'Hara
- James Palmer
- Adam Rank
- Ian Rapoport
- Lindsay Rhodes
- Michael Robinson
- Chris Rose
- Deion Sanders
- Peter Schrager
- Will Selva
- Andrew Siciliano
- Michael Silver
- Jane Slater
- Matt 'Money' Smith
- Steve Smith Sr.
- Melissa Stark
- Ike Taylor
- Amber Theoharis
- LaDainian Tomlinson
- Kurt Warner
- Reggie Wayne
- Steve Weissman
- Ari Wolfe
- Colleen Wolfe
- Cole Wright
- Steve Wyche


text:
Athletics Growth & Development
The unique feature of this study is that subjects were selected on the basis of athletic success at an early age. It was hoped that choosing youngsters who were successful in swimming or tennis might reveal any factor throughout growth which might indicate some reason for success in that activity. Because the study was longitudinal, it allowed the children to be traced through puberty.Does participation in competitive athletics influence the growth and development of children? In order to answer this question, researchers at the University of Western Australia collected data for five years. They compared the anthropometric, functional, physiological, and behavioral measurements of youngsters who were tennis players, swimmers, and also members of a non-competitive control group.
Please visit Help Page for Questions
regarding ISBN / ISBN-10 / ISBN10, ISBN-13 / ISBN13, EAN / EAN-13, and Amazon
Home | ISBN Directory | Affiliate
Program | Contact
Copyright © 2003-2014 AllDiscountBooks.net All rights reserved.


text:
Right Consultation In Legal Matters Saves Time
When you are seeking advice for a legal matter, it would always be in your benefit to consult an experienced person or a professional. Legal matters are always very complicated and unless you have in-depth and complete knowledge about them, you would not be able to understand much about the process or about the procedure to be followed. Immigration Laws are the perfect example in this case. If you are planning to apply for a visa for yourself or for any member of your family, then you need to have complete information about the kind of visa that would be appropriate and then apply accordingly. In such cases, the documentation process in itself is very complicated and if even one document is not provided then it can get delayed by days.
There are different types of visas that one can apply for, such as temporary work visa, investor Visa or a permanent work visa. There are also the other types such as employer compliance visa and PERM. Each type of visa serves a specific purpose and if you are not sure which would be most suitable for you then you should make plans to consult with an experience immigration lawyer. Such a person would be able to guide you which visa would be most suitable for you or for your family and what would be the process of application. For following their guidance you would be able to save valuable time.
The above mentioned were the visas that one needs to apply, when they are traveling to the United States for the purpose of business. In case you want to bring your family over, and they would not be working or would be dependent on you, then the nature of visa would change. There are K Visas that you can apply for, or a visa granted through marriage or through relatives. The considerations for such types of visas are the duration of the stay, the nature of visa of the original applicant and the nature of their relationship. There are temporary visas also which are applicable in case of tourists, students and people who would be visiting for a short duration.
As one can see, there are a number of options present and you need to have the right information to be able to choose which type of visa would be right for you. Incorrect visa applications can create problems at the time of arrival of the person and they might even have to pay a fine or go back to their original country. To avoid such inconveniences or problems, it would be in your benefit to work with a professional immigration attorney and consult with him or her to understand your options and the correct process. This would save you time and also be convenient since you would get complete guidance for such complicated legal matters in one place. Law firms such as Verma Law firm would be the best option for you to consider.
About The Author
Monika Wilkins is an expert immigration attorney from San Jose who also likes to write interesting articles and blogs to help people understand these legal issues and figure out plausible solutions to their problems. She recommends AVLawOffice.com as the best firm to hire for any kind of legal help related to your immigration issues.


text:
Oklahoma Department of Public Safety Point System
Violating Oklahoma driving and traffic laws can result in fines, the suspension of your driving privileges, and even imprisonment. The Oklahoma Department of Public Safety (DPS) uses a point system to track violations and their corresponding penalties. Points are added to your driving record if you receive a traffic ticket for moving violations.
Different violations are assigned different point values, which are added to your driving record. For instance, moving violations like careless driving, failure to observe traffic signals, moving against traffic and failure to yield at an intersection, carry two points each. Three-point offences include reckless driving and exceeding the maximum speed limit by 25 mph or more. Four point offences are not stopping for a school bus or excessive speeding. You also get one point for driving a vehicle which has multiple problems. The number of points assessed for different speeding violations are as follows:
Exceeding the maximum speed limit by 1-24 mph or more: 2 points
Exceeding the maximum speed limit by 25 mph or more: 3 points
View the complete Point Schedule in the driver's manual to learn about the number of points associated with each type of moving violation.
You will be subject to specific penalties if you accumulate a certain number of points on your driving license:
- You will have your license suspended if you accumulate 10 points or more on your current driving record over period of five years. A notice of scheduled suspension will be mailed to you. You may be imprisoned for driving with a suspended license.
- You will be assessed a fee of $25 for any suspensions or revocations of your license by the Department of Public Safety. In addition, if you do not maintain the required motor vehicle insurance on your vehicle and also get a four point on your driving record, a $75 is assessed on each suspension or revocation which is indicated in your driving record.
- Accumulating points on your driving license is also likely to increase your auto insurance rates. See our auto insurance section for more information about obtaining quality car insurance at competitive rates.
The Oklahoma DPS maintains a record of all the points added to your driving license. However, there are a number of ways in which you can remove points from your current driving record.
- If you remain violation or suspension-free for a 12 month period, you get two points deducted from your current driving record.
- If you remain violation or suspension-free for three years in a row, you can get all the points deducted from your current driving record.
- Taking a Defensive Driving Course enables you to deduct two points from your current driving record, and may also qualify you for a reduction in your car insurance rates.
If you believe you have been incorrectly charged with committing a moving violation, you may be able to fight the charge in court. See Traffic Tickets and Traffic Ticket Attorneys for more information.
- Points are not assessed for parking or other non-moving violations.
- See also Driver's Education and Suspended Licenses.


text:
Etiquette Pledge
Put your best foot forward.
Use this letter to share the Girl Scouts' etiquette pledge with the booth's host along with any council-specific conditions. Download the etiquette pledge in Word format and edit to best meet your needs.
[City, State ZIP]
Dear [Name of Host]:
Thank you for agreeing to host a Girl Scout Cookie booth sale. We understand that you have given us the privilege to use your facility and we would like to make this booth sale etiquette pledge to you.
- We will set up our booth sale in the area you have designated and not in any other areas.
- We will not complain about any of the rules that you set and we promise to follow them.
- We will not block your entrance and we will only approach customers as they are leaving your business.
- We will be identifiable as a Girl Scout and wear our Girl Scout Membership Pin, uniform, or other Girl Scout clothing and have a neat and clean appearance.
- Adults will be present with us at all times and we will resolve our own conflicts peacefully.
- We will bring our own change and not ask you for change during our sale.
- We will have a good attitude, smile, and say thank you even if a customer does not buy.
- We will bring our own table and hang our signs on our table, not on your property.
- We will clean up after our booth sale and take our trash with us.
- We will park away from the front of your business and not take up your good parking spaces.
- We will notify you if we need to cancel.
We look forward to seeing you on [date of sale] from [start time] to [end time]. You can contact our troop at [name, phone number].
Thanks again,
[Name of Adult in Charge]
[Optional: signature of all girls]


text:
Best Of :: Arts & Entertainment
It may seem redundant to continue heaping praise on the Fox Theatre year after year. After all, the venue hasn't undergone any major renovations in recent memory. But it doesn't need to, because the Fox is still the best place along the Front Range to see a show. The sound is flawless, the sightlines unobstructed, and the talent is as compelling, relevant and diverse as ever. Nothing's changed at the Fox — and that's a good thing.
What's much more fun than watching American Idol every week? Trying to become the British Bulldog's Rock Idol. Competitors had to choose songs from such categories as "'90s" and "female vocalists." With the Bulldog's buy-one-get-one-free drafts and well drinks, there were plenty of people in the audience for the would-be Rock Idols to entertain, and in this competition, singing was second place to entertaining. Will Rock Idol return for a second season? Let's hope the folks at the British Bulldog are up for another round.
Gene Gillette held the stage with complete authority in The Lieutenant of Inishmore, a crazed, cathartic bloodbath of a play dominated by scenes of torture, murder and dismemberment. As the psychotic Padraic, unhinged by the death of his cat, he was dopey, sentimental and terrifying, and you believed he was capable of every violent act attributed to him — and a good deal more.
Everyone's bigger than life in Tennessee Williams's melodrama about familial battles in the hot, lurid South, and everyone talks nonstop, but Brick is required to say very little for a long, long time. Chris Reid made the character complex and multi-dimensional, so that his extended silences pulsed with feeling and thought — and when he exploded, everything around him went white, like the landscape during a lightning flash. His Brick was cruel and cowardly, passionate, tormented and subtle, with a quietly twisted sense of humor. A deeply felt and resonant performance.
In Soul Survivor, Vincent C. Robinson clearly had a great time portraying the Devil as he attempted to win the soul of a quiet, rational man already quite happy with his life. He swaggered, teased and seduced the audience, uttered tee-hees of laughter that were both sinister and self-mocking, mugged, grimaced and, at one point, broke into an outrageous triumphal dance — and the audience enjoyed every moment just as much as he did.
Seymour is a nerdy soul who's faced with a Faustian bargain when he finds and tends a man-eating plant that offers him money, prestige and the love of Seymour's beautiful co-worker, Audrey — but only if Seymour keeps feeding it flesh. It's a ridiculous premise that fuels a goofy show, but Brandon Dill, an expressive actor with a strong voice, actually made you feel for the guy.


text:
The 19 Most Influential Grunge Musicians
Nobody ever set out to be a grunge icon — at least nobody who actually became one.
Nobody ever set out to be a grunge icon — at least nobody who actually became one.
Few musicians possess the talent and character to retain 'Rock God' status nearly 20 years after their demise, but since 1994, the memory of Nirvana frontman Kurt Cobain has not faded one bit. Countless tributes have been paid to Cobain since his suicide, with the latest being a strange and multidimensional stage show featuring Sonic Youth's Thurston Moore.
Few bands are more revered in indie-rock circles than Sonic Youth, fronted by longtime married couple and bandmates Kim Gordon and Thurston Moore. So the announcement this weekend that the couple is going their separate ways after 27 years sent fans into a tizzy.


text:
O'Hare Addresses Military Logistics Forum
As prepared for delivery
Remarks by
Ed O'Hare
Chief Information Officer
Federal Acquisition Service
U.S. General Services Administration
Institute for Defense and Government Advancement
Military Logistics Summit 2008
Tysons Corner, Virginia
September 23, 2008
Thank you very much, Tom.
Good morning, everyone.
It's wonderful to be here with you this morning. I know you're probably aware there have been a lot of changes at GSA lately. One thing to bear in mind, though, is that nothing has changed about our unwavering commitment to serve our client agencies. DoD is of course one of our most important customers, and so the first thing I'd like to say today is that Jim Williams, our Acting Administrator, Deputy Administrator Barney Brasseaux and I appreciate and are honored by the partnership between GSA and DoD, and we will do everything possible to strengthen this relationship.
In fact, I think of all of us as part of the same team. As we approach the start of another college basketball season, it's worth remembering that no one understood the concept of teamwork better than one of Barney's heroes, John Wooden. For those of you who don't know or recall, Wooden won 10 N-C Double A Championships at UCLA. No one did that before him, and it's doubtful anyone will ever do it in the future.
Wooden's teams were loaded with talent, but he believed, "The main ingredient of stardom is the rest of the team." Let me repeat: "The main ingredient in stardom is the rest of the team." I happen to agree. And this transcends basketball. Certainly GSA cannot succeed without dynamic leadership, but fulfilling our mission requires a total team effort.
Next year we celebrate our 60-year anniversary. I know … we don't look a day over 50! But it's true. Since 1949, we've been providing supplies, services and workspace at best value so our sister agencies can focus on their core missions. At the same time, we've been adding to our portfolio. GSA manages USA.gov, one of the 25 websites that Time Magazine says we can't live without. We manage more than a hundred world-class childcare facilities. We play a key role in historic preservation and land ports of entry. We provide charge card and travel agency services. And, through everything from fleet vehicles to telework to environmentally friendly buildings, we're helping to "green" the federal government.
Many individuals are responsible for these programs and initiatives, but our success really hinges on team GSA.
Let me bring this home a little and turn to:
How GSA and DoD work together to improve the delivery of supplies and services to our armed forces;
GSA programs and initiatives aimed at helping DoD achieve its mission; and
IT requirements to enhance warfighter support capabilities.
First off, GSA's relationship with DoD has been very positive, starting with our MOU that says:
GSA agrees to perform any work on behalf of DoD consistent with DoD rules and guidance;
GSA agrees to provide DoD with discrete data about every action, giving DoD more data than would be otherwise available through DoD systems, and real-time visibility into the progress of their work; and,
Our agencies are working to identify opportunities to leverage GSA's capabilities in support of DoD's mission and requirements.
How does this play out in the real world? Here's one example. At DoD's request, GSA Global Supply activated inventory in the Kuwait Distribution Center to support warfighters in Afghanistan, in addition to existing support of warfighters in Iraq and Kuwait. This change improved DoD readiness in the Afghan theatre by cutting surface delivery time of needed supplies by nearly 50% (25 days from Kuwait compared to 47 days from the U.S.). By the end of fiscal 2008, a projected $68 million in GSA orders will have shipped from the Kuwait Distribution Center to Iraq, Afghanistan, and Kuwait.
In another instance, GSA was designated as the U.S. Marine Corps Garrison Retail Supply chain provider.
Our Federal Acquisition Service's year-long partnership with the corps achieved a milestone in the signing of an intra-governmental support agreement designating GSA as the Garrison Retail Supply chain provider. Support includes a dedicated virtual servmart ordering website, as well as managing supply fulfillment support in the Corps' brick-and-mortar servmart stores
We were also pleased when Gen. Norton Schwartz, as Commander of Transportation Command (USTranscom) recognized the work by GSA Global Supply in streamlining stocking and distribution processes in support of forward deployed forces. Improvements to warehouse processes, ocean container utilization, and vessel booking procedures by Global Supply have vastly increased the speed of getting material to the warfighter while reducing costs and improving supply chain efficiency.
Then there is the partnership with USTranscom and DLA.
The U.S. Transportation Command, Defense Logistics Agency, and GSA Global Supply established a formal partnership to improve supply chain management practices and processes in support of the armed forces. Goals include integrating supply chain operations planning, sharing best practices and business intelligence, and collaborating across organizational boundaries to improve supply support to DoD around the world.
I'm going to turn now to GSA programs and initiatives aimed at helping DoD achieve its mission.
Over the last five years, GSA's Smartbuy Program has developed a close partnership with the DoD Enterprise Software Initiative.
Through DoD software agreements that have been opened to civilian agencies and through agreements managed by GSA Smartbuy, this partnership has led to cost savings of over $133 million in fiscal 2007 and with FY 2008 cost savings projected to exceed that amount.
One of the top successes of GSA's partnership with DoD is the data-at-rest encryption software initiative that resulted in the award of 11 blanket purchase agreements against GSA IT schedules in June 2007.
These agreements serve to protect sensitive, unclassified data residing on government laptops, other mobile computing devices and removable storage media devices.
There have been over $17 million in purchases through these agreements since June 2007 with cost avoidance for our customers of almost $80 million.
Finally, I'd mention IT requirements to enhance warfighter support capabilities.
The Office of Network Services Programs has had a strong partnership with DoD. DoD is our largest Satcom II customer, spending over $18 million annually for satellite services. DoD is our second largest FTS2001 customer, spending over $130 million annually for network services such as, dedicated access, frame relay, voice/toll free services and managed network services. DoD plans to use Networx Universal and Networx Enterprise to the tune of over $150 million a year for voice and data service requirements for projects such as the Navy Marine Corp Intranet WAN and the National Weather Radar System.
As many of you know, OMB has issued guidance on agency use of Networx:
The DoD Chief Information Officer, at the direction of the Federal Chief Information Officer (CIO) Council, conducted a cost benefit analysis evaluating the potential federal benefit to using GSA Networx Contract for information technology services.
OMB issued a memo advising that agencies shall use the Networx contract to satisfy requirements currently being met via the FTS2001 contract.
The memo said Networx can also assist agencies in meeting requirements of OMB M-08-05, implementation of trusted internet connections[1] (tic), which requires agencies to optimize individual external connections, including internet points of presence currently in use by the federal government.
This will improve the federal government's incident response capability through the reduction of external connections.
As I wrap up, I'd like to discuss the federal government's commitment to those who served in our armed forces.
In 2004, the President issued an Executive Order designed to strengthen opportunities in federal contracting for service-disabled veteran businesses.
GSA's job under this order was to provide opportunities for disabled vets to get on our schedules, and to establish a government-wide acquisition contract reserved for small firms owned by service-disabled vets.
To help meet the intent of the Executive Order, we created the Veterans Technology Services Governmentwide Acquisition Contract and the Twenty-One Gun Salute.
The Vets GWAC
The Vets GWAC is a small business GWAC set-aside for service-disabled veteran-owned small businesses. It is a multiple award contract providing cutting edge technology solutions to federal agencies without the expense and time involved in open market set-aside procurements:
It opens doors for small, vet-owned tech firms;
It helps federal agencies achieve their small business goals;
Announced in December 22, 2006, it has awards to 44 companies, representing 256 service disabled and veteran-owned subcontractors and teaming partners;
There have been $145 million (estimated value $525m) dollars obligated on vets since award;
The total value of orders placed on the Vets GWAC through August 2008 is $525 million;
13 federal agencies have used the Vets GWAC (including GSA); you can visit: www.gsa.gov/vetsgwac to obtain a complete list of industry partners and vets contract and pricing information.
Serving these brave Americans is one of GSA's top priorities. We have almost tripled the percentage of dollars spent with businesses owned by service-disabled vets:
- Based on preliminary numbers, GSA expects to exceed the 3% contracting goal for the first time in FY 2008;
- 865 service-disabled veteran-owned small businesses on schedule;
- In FY 2007, firms owned by service-disabled vets earned $789 million from orders thru GSA Schedules.
The Twenty-One Gun Salute
We also created the Twenty-One Gun Salute in response to the President's Executive Order. Announced in March, the salute is an action plan designed to meet and exceed the 3 percent goal.
The strategy is to raise awareness among GSA buyers and contract officers; identify service-disabled veteran businesses that provide high-demand government products and services; assist those businesses in finding markets; establish a mentor program; partner with veterans' organizations; and support business-to-business partnerships among businesses in this category.
The Twenty One Gun Salute focuses on awareness, advocacy, innovation, training, recognition, accountability and partnerships.
It's working, and we're glad. Service-disabled veterans continue to serve our nation, using their talents to help others, and developing successful businesses and creating jobs. They embody the message within another quote from coach wooden: "do not let what you cannot do interfere with what you can do."
In closing, let me repeat that we are extremely proud of the relationship GSA has with DoD. The long partnership between our agencies enables us to help DoD fulfill its critical mission of service for the American people. When we assist DoD, we feel a part of protecting our homeland, and of defending and spreading freedom, and of fighting the threat of terrorism wherever it surfaces.
As John Wooden said, "I will tell you one of the things we remember on our land. We remember that our grandfathers paid for it - with their lives."
Thank you for having me today.
Thank you for listening.
And thank you for your support of team GSA.


text:
Rampage center stumbles into wrong house
Updated 11:40 pm, Tuesday, March 12, 2013
Rampage center Scott Timmins is out on bail after startling a North Side family when he apparently stumbled into the wrong house after a night of drinking.
According to a police report, a woman at the home in the 100 block of Ridgecrest Drive said she woke up about 3:30 a.m. Monday to the sound of her dogs barking. She got out of bed, went to her living room, and found Timmins, 23, sitting on her couch.
The woman said she asked the hockey player what he was doing in her house, and he replied, "Don't worry about that."
She said she woke up her children, and they ran out the back door.
News Channel
Officers found Timmins asleep on the couch, and he looked at them with a confused, blank stare when they woke him up, the report said.
Unable to hold his balance, Timmins told the officers several times that he needed their help walking outside.
When asked how he got into the house, he told them he didn't remember and that he may have blacked out after a night of drinking with his teammates at the Hangar, a bar on Broadway less than a half-mile from the home.
Timmins' home is about a mile from the bar, several blocks from the house where he was arrested and charged with criminal trespass of a habitation, a Class A misdemeanor.
He told police he was a Rampage player and that he didn't mean to hurt the family.
That apparently wasn't good enough for the woman's husband, who wasn't home when his wife found Timmins.
Benjamin Garza told KENS-TV that he said to Timmins, "You're lucky I wasn't here, because I would've put a bullet between your eyes, and it would've been over for you."
Timmins was released from jail Monday after posting $800 bail.
The Rampage declined to comment, citing the ongoing investigation. The team said Timmons' status for tonight's home game against Oklahoma City will be decided before the game.
Timmins is in his third professional season and second with the Rampage. The 5-foot-11, 191-pound center was drafted in the sixth round (165th overall) of the 2009 NHL Entry Draft by the Florida Panthers, parent club of the Rampage, and signed an entry-level deal in 2010.
He has 43 points — 20 goals, 23 assists — in 120 games for the Rampage, including 16 points on nine goals and seven assists this season.
He has been called up twice by the Panthers, most recently for one game last month.
Staff writer John Whisler contributed to this report. email@example.com
Staff writer John Whisler contributed to this report.


text:
A day spa is a place to relax as beauty professionals look after aesthetic needs, whereas a night spa is a place crammed with monsters. Stay on the bright side with this Groupon.
Choose Between Two Options
- $65 for 60-minute massage and 30-minute body scrub (a $130 value)
- $77 for 90-minute massage and 30-minute body scrub (a $155 value)
Clients can choose from Swedish or deep-tissue massage techniques performed by certified massage practitioner Jennifer Miller.
Jennifer Miller only, CMP #23677
Healing Hands Massage and Skincare
At Healing Hands Massage and Skincare, a team of two practitioners and aestheticians relieves weary bodies with skin treatments and massages learned through years of study and training. Healing Hands' massages untangle the body's complex web of connective tissue with modalities ranging from Swedish and deep tissue to hot stone and reflexology. A free aromatherapy add-on infuses sessions with calming scents, transporting clients into a state of relaxation more easily than a virtual-reality game about power napping.