text:
Oahu Hawaii Beaches:
by Region,
including beach descriptions and facilities
| With 112 miles of sandy shoreline, an average year round water temperature of 75-80 degrees Fahrenheit, a plethera of activities, Waikiki (the most famous strip of beach in the U.S.), and over 130 beaches of varying types, Oahu offers a beach for everyone's style.
Some of Oahu's most beautiful beaches are uncrowded due to tourists and residents alike visiting the most popular beaches. The Windward (East) side of the island has many untouched beaches but there's a reason they call it Windward! On a windy day, you may get sandblasted, on a calmer day you may be just perfect! North Shore beaches can be calm and lovely for swimming in summer months, but turn treacherous, potentially deadly in the winter, with surf reaching up to 50 feet! The beaches on the Leeward (West) side of Oahu tend to have calmer surf but are more crowded.
Beach Activities on Oahu are almost endless! Body surfing, windsurfing, surfing, longboarding, surf lessons, watching professional surfers... Are you noticing a theme here? Boogie boarding, snorkeling, diving, beachcombing, tidepooling, picnicking, volleyball, kayaking, hiking, people watching, sunbathing, jet skiing, waterbiking, canoeing, catamaran rides ... Need we go on?
Now that we've mentioned the fun, there are a few hazards to be aware of while visiting Oahu's fantastic beaches; Surf, limu (stinging seaweed), portuguese man of war, box jellyfish and theft. (Click on the links to learn more.) However, don't let any of these prevent you from enjoying the ocean while on the island! Just use common sense, obey posted warnings, and talk to the lifeguards if you have any questions!
Select a region below for a complete list of Oahu Beaches or
When visiting the beach, please follow these Basic Ocean Safety Tips provided by lifeguards:
|Oahu Hawaii Information & Travel Guide
Activities, Lodging, Weddings, Restaurants...
| Site Map | Legal Disclaimer | Links | ADVERTISE |
Copyright © 2008-2013 AlohaIsles.com


text:
$ 1,010.00
This design comes with low-egg rails which taper back to an edge at the diamond-tail. A slight rail-to-rail concave under the nose incorporated with an overall flat bottom give this model some high performance capabilities to go along with its abundant nose riding qualities.
Recommended Fin: RA Custom Center Fin
Experience Level: Beginner to Expert
* Please note: Center Fin is not included, can be ordered separately. Custom board lead times are 6 to 8 weeks.
$ 1,050.00
It makes sense to ride a board that maximizes your fun regardless of the conditions. "What I Ride" utilizes a 60/40 rail configuration which, in combination with a nifty tear...
$ 1,600.00
Our take on a 'Wood Veneer', this board can be ridden or beautiful enough to hang on the wall. It makes sense to ride a board that maximizes your fun...
$ 1,050.00
Just like the well proven What I Ride Model but with a round tail for increased turning ease and responsiveness. The "What I Ride" Round Tail also utilizes a 60/40...

subset: commoncrawl


text:
QUEBEC-HESSIANS-L ArchivesArchiver > QUEBEC-HESSIANS > 2011-12 > 1324008759
From: Dominique Ritchot <>
Subject: [QUEBEC-HESSIANS] Adam Rohmann
Date: Fri, 16 Dec 2011 04:12:39 +0000
References: <00F435A1CDB54C008D78E2A7643C213C@OwnerPC>,<firstname.lastname@example.com>
In-Reply-To: <email@example.com>
Jean-Pierre Wilhelmy's book does not have all the names of the auxiliary soldiers. His book is mostly about the history. It sure has a list of soldiers who remained in Quebec, but with no further details.
My book, Les Troupes allemandes au Canada 1776 - 1783 (adapted in french from the one of Virginia Easley DeMarce), has the list of all the soldiers who were discharged and stayed in Quebec and Canada.
As for Adam Rohmann, he came with the Brunswick troop, Riedesel regiment, Speth compagny. He was discharged in Canada in June 1783. Married to Josephte Moreau, most probably in Albany NY (where two of ther six children were born). He had another son with a woman named Marguerite Picard (who at this point remains a mystery).
Only one soldier bearing the name Rohmann. His name changed to Romaine (french spelling).
---------------Adam Rohmann est venu avec les troupes de Brunswick, regiment de Riedesel, compagnie de Speth. Il a été démobilisé en Juin 1783. Il s'est marié avec Josephte Moreau (date et endroit inconnus). Deux de ses six enfants sont nés à Albany NY. Il a eu un fils avec une dame nommée Marguerite Picard (qui demeure un mystère).
Il n'y a qu'un soldat qui corresponde à cet individu. Son nom a évolué en celui de Romaine.
> From:
> To:
> Date: Thu, 15 Dec 2011 20:20:56 -0500
> Subject: Re: [QUEBEC-HESSIANS] Adam Klein
> Hi Ellen Paul
> WOW very nice write up on Adam Klein a real treasure for the family. Do
> you have a list of other Hessians in you report you may wish to share ?
> I am interested in ROHMANN, Adam and / or ROMAIN(e), Adam I am still
> confused if this is two different people or one person.
> I was told in the book " LesMercenaires Allemands un Quebec by Jean Pierre
> Wilhelmy " the front of the book has all the names of the soldiers and
> Adam's last name is ROHMANN, it then has a section that mentions all the
> soldiers who decided to stay in Canada and Adam's last name is spelled as
> I found this land petition name this time is spelled ROMAINE
> Name: ROMAINE, Adam
> Year: 1787 -1829
> Volume: 48 line 140
> Page: 24766-24769
> Microfilm: C-2512
> sorry rambling on, I was just very impressed with your Adam Klein info and
> wanted to say WELL DONE :-)
> Cheers
> Sheila Stewart-Lafleur
> ----- Original Message -----
> From: "Ellen Paul" <>
> To: <>; <>
> Sent: Thursday, December 15, 2011 5:00 PM
> Subject: [QUEBEC-HESSIANS] Adam Klein
> Dear Shae Griffin:
> I am not a descendant of Adam Klein, but he was one of the subjects
> [actually his son, Michel] of my paper presented at the 9th North American
> Fur Trade Conference and 12th Rupert's Land Colloquium in 2006.
> Here is the pertinent part of the paper:
> Adam Klein was also a Jaëger of Wittgenstein's 4th Company, the batman or
> personal servant of one of the regimental officers. He may already have been
> a widower when he arrived in North America, because when he remarries in
> August of 1779, the register names his first wife as Anne Caton. It is
> possible that she accompanied him to North America--each company was allowed
> to bring up to nine women and before embarking there had been a flurry of
> marriages in Germany. After the war the family stayed in Laprairie. Adam
> Klein and his wife are sponsors to several other Jaëger baptisms and
> weddings. Three daughters and a son were born to them and sometime after
> 1787 the family moved to Montréal where Geneviève died in April of 1791 at
> the age of 27. Drawing on his military experience Adam Klein was now
> described as a sutler and by May of 1792 he had married for a third time. In
> 1796 he served as father of the groom when fellow-Jaëger and
> sometime-voyageur, 46 year-old Michel Ma
This thread:
|[QUEBEC-HESSIANS] Adam Rohmann by Dominique Ritchot <>


text:
[Date Index]
[Thread Index]
[Author Index]
tangent in turning point
I'm looking for a software which can solve
the following problem:
I've measured some values for the velocity
of a test vehicle in a regular short period
of time. Thus, I have pais of values (velocity
x in time t). I would like to use these values
to draw a graph and find then the turning point.
Hence, the program should draw a tangent through
the turning point.
Please tell me if mathematica is able to perform
this task and give me a short instruction for the
Thank you very much.
Best regards,
Christian Christmann


text:
Washington (Mar. 29)
(Jewish Daily Bulletin)
Hearings on the Dickstein and MacGregor bills for reuniting families separated because of the immigration restrictions were concluded by the House Immigration Committee yesterday and the committee started consideration of these bills at an executive session immediately following the hearings.
The executive session will continue today, no definite conclusions having been reached yesterday.
Francis H. Kennicutt, representing the Immigration Restriction League and chairman of the Committee on Immigration of the Key Men of America, appeared before the committee opposing any change in the present law which would increase the total immigration to the United States. In reply to questions he declared that he is not opposed to amending the law so as to give special consideration to uniting families without, however, increasing the total immigration.
Congressman Dickstein's bill would increase the total immigration since it asks for exemption from the quota of the parents and children up to 21 and husbands of American citizens and the wives and children under 21 of declarants, whereas Congressman MacGregor's bill allows only for preference within the present quota.
Congressman Dickstein cross examined. Mr. Kennicutt, who made many contradictions in his testimony.
A difference in view seems to have developed between Congressman Golder and Congressman Dickstein regarding the character of the amendments which should be made. At the hearing yesterday Congressman Golder indicated that he would be satisfied if the entire quotas were turned over to the relatives of declarants. Dickstein pointed out that in East European countries this would prevent any aliens except such relatives from procuring visas and would thus nulify all except relative immigration. This, he said, would be an unwarranted concession to the restrictionists, since relative relief should be granted in addition to the present immigration allowed by law and not at the expense of the existing immigration.
It is expected that progress will be made at today's session toward the clarification of the present differences.


text:
Independent Activity Fund: Bethesda-Chevy Chase HS
2017 Activity Fund Report (Published Mar 01, 2017)
2015 Activity Fund Report (Published Oct 26, 2015)
2014 Activity Fund Report (Published Apr 22, 2014)
2013 Activity Fund Report (Published Jan 09, 2013)
About the Independent Activity Fund
Independent Activity Funds (IAF) are established to promote the general welfare, education, and morale of students, as well as to finance the recognized extracurricular activities of the student body. Audits are conducted to make sure the funds are being spent in compliance with MCPS policy and to offer suggestions for continuous improvement. IAF reports completed after January 1, 2012 are posted to this site.
Bethesda-Chevy Chase HS
www.montgomeryschoolsmd.org/schools/bcchs/4301 East-West Highway
Bethesda, MD20814
Phone: 240-740-0400
Fax: 240-497-6306
Dr. Donna R Jones, Principal
Staff Directory


text:
I just sold a print, "Hirut", to someone who lives in BahirDar, Ethiopia. The proceeds from all print sales enable me to support projects in Ethiopia, so this makes me very happy.
This print will be 16X24 inches, printed by PushDot Studio, and will be hung in The B+B Guest Annex that is rented to visitors.
Come for a visit to beautiful Ethiopia!


text:
How to Buy
Solutions Overview
This script is Copyright (C) 2009-2016 Tenable Network Security, Inc.
Synopsis :
The remote application server is affected by multiple vulnerabilities.
Description :
IBM WebSphere Application Server 7.0 before Fix Pack 3 appears to be
running on the remote host. As such, it is reportedly affected by
multiple vulnerabilities :
- Under certain conditions it may be possible to access
administrative console user sessions. (PK74966)
- The administrative console is affected by a cross-site
scripting vulnerability. (PK77505)
- If APAR PK41002 has been applied, a vulnerability in the
JAX-RPC WS-Security component could incorrectly
validate 'UsernameToken'. (PK75992)
- Sample applications shipped with IBM WebSphere
Application Server are affected by cross-site scripting
vulnerabilities. (PK76720)
- Certain files associated with interim fixes for Unix-
based versions of IBM WebSphere Application Server are
built with insecure file permissions. (PK77590)
- The Web Services Security component is affected by an
unspecified security issue in digital-signature
specification. (PK80596)
- It may be possible for an attacker to read arbitrary
application-specific war files. (PK81387)
- A security bypass caused by inbound requests that lack
a SOAPAction or WS-Addressing Action. (PK72138)
See also :
Solution :
Apply Fix Pack 3 (188.8.131.52) or later.
Risk factor :
High / CVSS Base Score : 7.5
CVSS Temporal Score : 6.2
Public Exploit Available : true
Family: Web Servers
Nessus Plugin ID: 36133 ()
Bugtraq ID: 341043433034358345063559435610
Get Nessus Professional to scan unlimited IPs, run compliance checks & more
The cookie settings on this website are set to 'allow all cookies' to give you the very best website experience. If you continue without changing these settings, you consent to this - but if you want, you can opt out of all cookies by clicking below.


text:
It only takes a minute to get started. Fill out our uncomplicated sign up form and login to the site.
This step is noncompulsory but will greatly raise your chances of getting interest from other members on the website. Type a little about yourself, your hobbies and upload some good photographs of yourself.
Use our website's state-of-the-art search to discover over 60s members who fulfill your criteria. Or just leaf through listings and discover daters that arouse your interest.
Identified someone who appeals to you? Send a message to them or just a wink and await their reply. With a little luck you'll be on your way to a lifetime of happiness.
It only takes a few clicks


text:
|Home | About | Journals | Submit | Contact Us | Français
Osteoarthritis is often a progressive and disabling disease, which occurs in the setting of a variety of risk factors – such as advancing age, obesity, and trauma – that conspire to incite a cascade of pathophysiologic events within joint tissues. An important emerging theme in osteoarthritis is a broadening of focus from a disease of cartilage to one of the 'whole joint'. The synovium, bone, and cartilage are each involved in pathologic processes that lead to progressive joint degeneration. Additional themes that have emerged over the past decade are novel mechanisms of cartilage degradation and repair, the relationship between biomechanics and biochemical pathways, the importance of inflammation, and the role played by genetics. In this review we summarize current scientific understanding of osteoarthritis and examine the pathobiologic mechanisms that contribute to progressive disease.
Osteoarthritis (OA) is characterized by a progressive loss of articular cartilage accompanied by new bone formation and, often, synovial proliferation that may culminate in pain, loss of joint function, and disability. A variety of etiologic risk factors and pathophysiologic processes contribute to the progressive nature of the disease and serve as targets of behavioral and pharmacologic interventions. Risk factors such as age, sex, trauma, overuse, genetics, and obesity can each make contributions to the process of injury in different compartments of the joint. Such risk factors can serve as initiators that promote abnormal biochemical processes involving the cartilage, bone, and synovium, which over a period of years result in the characteristic features of OA: degradation of articular cartilage, osteophyte formation, subchondral sclerosis, meniscal degeneration, bone marrow lesions, and synovial proliferation.
A genetic disposition to OA has been clear since it was first reported by Kellgren and coworkers [1] that generalized nodal OA was twice as likely to occur in first-degree relatives as in control individuals. Twin pair and family risk studies have indicated that there is a significantly higher concordance for OA between monozygotic twins than between dizygotic twins, and that the hereditable component of OA may be in the order of 50% to 65% [2]. However, because of the prevalence of OA in the general population and extensive clinical heterogeneity, the precise genetic contribution to the pathogenesis of OA has been difficult to analyze. Moreover, it is clear that multiple genetic factors can contribute to the incidence and severity of OA, and that these may differ according to specific joint (hand, hip, knee, or spine), sex, and race. There is also evidence, given the variety of candidate genes that predispose to OA, that there may be an additive effect of individual genes in the development of disease [3].
Several candidate genes encoding proteins of the extra-cellular matrix of the articular cartilage have been associated with early-onset OA [4]. In addition to point mutations in type II collagen [5], inherited forms of OA may be caused by mutations in several other genes that are expressed in cartilage, including those encoding types IV, V, and VI collagens, as well as cartilage oligomeric matrix protein (COMP) [6].
Candidate genes for OA have also been identified that are not structural proteins. Among such candidates are the secreted frizzled-related protein 3, asporin, and von Wille-brand factor genes [7,8]. In follow-up studies it has been reported that the asporin, frizzled-related protein 3, and von Willebrand factor genes have now been found not to replicate in large Caucasian meta-analyses and that the association with growth differentiation factor (GDF)-5 in Caucasians has been confirmed in larger meta-analyses [9-12]. Finally, evidence from mouse models indicates that genetic disorders affecting the architecture of subchondral bone can cause OA. Mice with a null mutation of the latent transforming growth factor (TGF)-β binding protein-3, which regulates the activation of TGF-β, developed both osteosclerosis and OA [13]. In addition, a recent report demonstrated that a genetic defect of type I collagen resulted in rapidly progressive OA in a mouse model [14].
In recent population studies, genome-wide linkage scans have highlighted several specific genes involved in disease risk [15]. Chromosome 2q was positive in several scans, suggesting that this chromosome is likely to harbor one or more susceptibility genes. Two IL-1 genes (IL1α and IL1β) and the gene encoding IL-1 receptor antagonist (IL1RN), located on chromosome 2q13 within a 430-kilobase genomic fragment, have been shown to associate with the development of primary knee, but not hip, OA [16]. IL1RN haplotype variants have also been shown to associate with radiographic severity of the OA [17]. Recently, a genome-wide association scan has identified a cyclo-oxygenase (COX)-2 variant involved in risk for knee OA [18]. These genetic associations of genes such as IL1α, IL1β, IL1RN, and COX2 underscore the potential role of inflammatory pathways in the pathogenesis of knee OA.
Age is the risk factor most strongly correlated with OA, and therefore understanding age-related changes is essential. Age-related mechanical stress on joint cartilage may arise from a number of factors, including altered gait, muscle weakness, changes in proprioception, and changes in body weight. In addition, age-related morphologic changes in articular cartilage are most likely due to a decrease in chondrocytes' ability to maintain and repair the tissue. This is because chondrocytes themselves undergo age-related decreases in mitotic and synthetic activity, exhibit decreased responsiveness to anabolic growth factors, and synthesize smaller and less uniform large aggregating proteoglycans and fewer functional link proteins [19]. Age also appears to be an independent factor that predisposes articular chondrocytes to apoptosis, because the expression levels of specific pro-apoptotic genes (those encoding Fas, Fas ligand, caspase-8, and p53) are higher in aged cartilage [20,21].
Obesity is another important risk factor for OA [22]. An increase in mechanical forces across weight-bearing joints is probably the primary factor leading to joint degeneration. The majority of obese patients exhibit varus knee deformities, which result in increased joint reactive forces in the medial compartment of the knee, thereby accelerating the degenerative process [23]. Emerging data implicate a crucial role for adipocytes in regulation of cells present in bone, cartilage, and other tissues of the joint. The comparatively recently discovered protein leptin may have important involvement in the onset and progression of OA, and increase our understanding of the link between obesity and OA [24]. In addition, adipocyte-derived factors such as IL-6 and C-reactive protein appear to be pro-catabolic for chondrocytes. Further work is needed to determine whether leptin or other adipokines are important systemic or local factors in the link between obesity and OA.
Whether joint malalignment leads to the development of OA is a matter of debate [25]. However, the evidence does indicate that varus or valgus deformities are markers of disease severity and are associated with risk for progression of knee OA [26]. Indeed, there is evidence to suggest that much of the effect of obesity on the severity of medial compartment knee OA can be explained by varus mal-alignment [27]. Hunter and colleagues [28] have reported that enlarging or new bone marrow lesions occurred mostly in malaligned limbs, on the side of the malalignment. With regard to mechanisms, altered joint geometry may interfere with nutrition of the cartilage, or it may alter load distribution, either of which may result in altered biochemical composition of the cartilage [29].
Although hip OA is slightly more common in men, there is a marked increase in prevalence among women after the age of 50 years, particularly in the knee, and the cause of this increase – which has been ascribed to estrogen insufficiency – is poorly understood [30]. Articular chondrocytes possess functional estrogen receptors, and there is evidence that estrogen can upregulate proteoglycan synthesis [31]. In support of a role for estrogens in OA, there are human and animal studies indicating that estrogen replacement therapy reduces the incidence of OA [32,33], although prospective randomized trials to confirm these observations, particularly with respect to structure modification, have not been performed. It should be noted, however, that the evidence for a relation between estrogen deficiency and OA in women is inconsistent, and one 4-year study showed no effect of estrogen plus progestin versus placebo on symptoms or disability in postmenopausal women [34].
Chondrocytes embedded within the negatively charged cartilaginous extracellular matrix are subjected to mechanical and osmotic stresses [35-37]. One of the most exciting emerging areas is that chondrocytes, like osteocytes in bone, serve as mechano-sensors and osmo-sensors, altering their metabolism in response to local physicochemical changes in the microenvironment. Therefore, while obesity and joint misalignment are risk factors for OA in specific joints, the mechanism by which these risk factors initiate and perpetuate OA is largely mediated by biochemical pathways. Several groups have identified osmo-sensors and mechano-sensors in chondrocytes in the form of several ion channels, sulfate transporters and integrins [35-37]. In response to mechanical stress, changes in gene expression and an increase in production of inflammatory cytokines and matrix-degrading enzymes have been noted (Figure (Figure1)1) [38]. The recognition that chondrocytes act as mechano-sensors and osmo-sensors has opened up the possibility that these proteins could serve as novel targets for disease-modifying OA drugs.
OA is characterized by a loss of articular cartilage matrix, which is the result of the action of proteolytic enzymes that degrade both proteoglycans (aggrecanases) and collagen (collagenases). Native collagen has been shown to be cleaved by matrix metalloproteinase (MMP)-1, MMP-8, and MMP-13. Of the three major MMPs that degrade native collagen, MMP-13 may be the most important in OA because it preferentially degrades type II collagen [39] and it has also been shown that expression of MMP-13 greatly increases in OA [40]. Among the characteristic changes in OA cartilage is the development of the hypertrophic chondrocyte phenotype, characterized by increased production of MMP-13, type × collagen, and alkaline phosphatase. Kawaguchi [41] has provided evidence that the induction of the transcriptional activator Runx2 (runt-related transcription factor 2) under mechanical stress in turn induces the hypertrophic phenotype, which leads to type II collagen degradation (MMP-13 production), endochondral ossification, and chondrocyte apoptosis.
The aggrecanases belong to a family of extracellular proteases known as the ADAMTS (a disintegrin and metalloprotease with thrombospondin motifs) [39]. Two aggrecanases, ADAMTS-4 and ADAMTS-5, appear to be major enzymes in cartilage degradation in OA [40]. Recently, an ADAMTS-5 knock-out mouse and ADAMTS-5-resistant aggrecan knock-in mouse, both of which show protection from OA, have validated ADAMTS-5 as a target for OA [42,43].
IL-1 stimulates the synthesis and secretion of many degradative enzymes in cartilage, including latent collagenase, latent stromelysin, latent gelatinase, and tissue plasminogen activator [44]. The balance of active and latent enzymes is regulated by at least two enzyme inhibitors: tissue inhibitor of metalloproteinases and plasminogen activator inhibitor-1 [45]. These enzyme inhibitors are synthesized in increased amounts under the regulation of TGF-β.
The metabolic imbalance in OA includes both an increase in cartilage degradation and an insufficient reparative or anabolic response. The identification of anabolic agents that can be utilized to restore cartilage is an area of significant investigation. Molecules of interest include cartilage anabolic factors such as bone morphogenetic proteins, insulin-like growth factor-I, TGF-β, and fibroblast growth factors. Growth factors such as bone morphogenetic proteins have the ability to reverse catabolic responses by IL-1 [46]. Conversely, normal chondrocytes exposed to IL-1 or chondrocytes from OA patients exhibit decreased responsiveness to growth factors [47]. An understanding of the interaction between catabolic cytokines and anabolic growth factors could lead to the identification of molecules that restore the responsiveness of diseased chondrocytes to anabolic growth factors or inhibitors of inflammatory cytokines.
The role played by inflammatory cytokines and mediators produced by joint tissues in the pathogenesis of OA is attracting increased attention. Among the many biochemical pathways that are activated within joint tissues during the course of OA are mediators classically associated with inflammation, notably IL-1β and tumor necrosis factor (TNF)-α. These cytokines, in an autocrine/paracrine manner, stimulate their own production and induce chondrocytes to produce proteases, chemokines, nitric oxide, and eicosanoids such as prostaglandins and leukotrienes. The action of these inflammatory mediators within cartilage is predominantly to drive catabolic pathways, inhibit matrix synthesis, and promote cellular apoptosis. Thus, although OA is not conventionally considered an inflammatory arthritis, that concept – based historically on the numbers of leukocytes in synovial fluid – should be reconsidered. Indeed, 'inflammatory' mediators perpetuate disease progression and therefore represent potential targets for disease modification.
As noted above, a characteristic feature of established OA is increased production of pro-inflammatory cytokines, such as IL-1β and TNF-α, by articular chondrocytes. Both IL-1β and TNF-α exert comparable catabolic effects on chondrocyte metabolism, decreasing proteoglycan collagen synthesis and increasing aggrecan release via the induction of degradative proteases [48]. IL-1β and TNF-α also induce chondrocytes and synovial cells to produce other inflammatory mediators, such as IL-8, IL-6, nitric oxide, and prostaglandin E2. The actions of both cytokines are in part mediated by activation of the transcription factor nuclear factor-κB, which further increases their own expression and that of other catabolic proteins such as inducible nitric oxide synthase (iNOS) and COX-2, thus creating an autocatalytic cascade that promotes self-destruction of articular cartilage [49].
IL-1β and TNF-α are both synthesized intracellularly as precursors, converted through proteolytic cleavage to their mature forms by caspases – membrane-bound IL-1β-converting enzyme (ICE) and TNF-α-converting enzyme (TACE) – and released extracellularly in their active forms. The expression of both ICE and TACE has been shown to be upregulated in OA cartilage [50]. Inhibitors of both ICE and TACE are of interest as future therapeutic small-molecule antagonists of downstream IL-1β and TNF-α expression, respectively; studies with an ICE inhibitor are now underway in two murine models.
Osteoarthritic cartilage is also the site of increased production of both C-X-C and C-C chemokines. These include IL-8, monocyte chemoattractant protein-1, and RANTES (regulated on activation, normal T-cell expressed and secreted; also known as C-C chemokine ligand-5), as well as the receptors C-C chemokine receptor (CCR)-2 and CCR-5 [51]. RANTES induces expression of its own receptor, CCR-5, which suggests an autocrine/paracrine pathway of the chemokine within the cartilage. Monocyte chemoattractant protein-1 and RANTES promote chondrocyte catabolic activities, including induction of nitric oxide synthase, increased MMP-3 expression, inhibition of proteoglycan synthesis, and enhancement of proteoglycan release.
Chondrocytes from human OA cartilage explants express COX-2 and spontaneously produce prostaglandin E2 [52]. We have recently reported that prostaglandin E2 produced by OA cartilage explants decreases proteoglycan synthesis and enhances the degradation of both aggrecan and type II collagen. These effects are associated with downregulation of MMP-1 and upregulation of MMP-13 and ADAMTS-5, and are mediated via engagement of the prostaglandin E receptor 4 (EP4) [53]. How the divergent synthesis of MMP-1 and MMP-13 is regulated remains unknown, but we previously reported that upregulation of the nuclear orphan receptor NURR1 (NR4A2) in OA cartilage causes similar divergent effects. This suggests that the effect of prostaglandin E2 on MMP-1 and MMP-13 may be a result of NURR1 activation (NR4A2) [54]. In their interesting recent report of a genome-wide scan, Valdes and coworkers [18] identified a COX-2 variant that was associated with increased risk for knee OA – a finding that underscores the possible importance of this signaling pathway in the pathogenesis of knee OA.
Among the inflammatory mediators that are of interest in the pathogenesis of OA are both oxygen and nitrogen-derived free radicals. Reactive oxygen species such as superoxide anion, hydrogen peroxide, and hydroxyl radicals directly promote chondrocyte apoptosis, most probably via mitochondrial dysfunction [55,56].
Nitric oxide, produced by the inducible isoform of nitric oxide synthase (iNOS), is a major catabolic factor produced by chondrocytes in response to pro-inflammatory cytokines such as IL-1β and TNF-α [57]. Considerable evidence indicates that the overproduction of nitric oxide by chondrocytes plays a role in the perpetuation of cartilage destruction in OA. Although normal cartilage does not express iNOS or produce nitric oxide without stimulation by cytokines such as IL-1, OA cartilage explants spontaneously produce large amounts of nitric oxide [58].
Nitric oxide exerts multiple effects on chondrocytes that promote articular cartilage degradation [57]. These include inhibition of collagen and proteoglycan synthesis; activation of metalloproteinases; increased susceptibility to injury by other oxidants (for example, hydrogen peroxide); and apoptosis. Several studies have implicated nitric oxide as an important mediator in chondrocyte apoptosis, a feature that is common in progressive OA. There is evidence that apoptosis results from the formation of peroxynitrite, a toxic free radical produced by the reaction of nitric oxide and superoxide anion [59].
Nitric oxide and its derivatives may also play protective roles, however, because protease activity and proteoglycan degradation are enhanced when nitric oxide production is blocked [60]. In murine models the development of surgically induced OA can be accelerated in mice that are knocked out for IL-1β, IL-1-converting enzyme, or iNOS. This suggests that a certain level of these molecules may be necessary to maintain a healthy joint and that complete pharmacologic suppression may be detrimental [61]. The protective roles played by nitric oxide in multiple cell types may reflect differing properties of the redox form of the molecule produced in the microenvironment [62].
Osteophyte formation and sclerosis of subchondral bone are hallmarks of OA. It has been theorized that osteophytes occur as a result of penetration of blood vessels into the basal layers of degenerating cartilage, or as a result of abnormal healing of stress fractures in the subchondral trabeculae near the joint margins [63]. TGF-β, when introduced into the joint in experimental animals, induces osteophyte formation, and TGF-β expression is observed in osteophytes in patients with OA [64,65].
With regard to subchondral bone sclerosis, it has been suggested that excessive loads may cause microfractures of subchondral trabeculae that heal via callus formation and remodeling. Whether subchondral sclerosis precedes the onset of OA or is a change that occurs but is not required for cartilage degeneration is not known. However, strategies targeted at bone disorders such as osteoporosis, and molecular targets that alter osteoclast and/or osteoblast function may represent opportunities to modulate pathologic subchondral changes in OA, and are therefore under consideration in efforts to develop disease-modifying treatments.
Felson and coworkers [66] reported that medial bone marrow lesions observed on magnetic resonance imaging (MRI) are associated with both knee pain and the risk for disease progression. However, it should be noted that, depending on size and location, the significance of bone marrow lesions in the individual patient might vary. The presence of bone marrow lesions and their relation to progression has been explained in part by an association with limb alignment [66]. The histopathologic nature of bone marrow lesions in OA is not yet clear, and it is probable that a number of tissue abnormalities such as microfractures, cysts, and avascular necrosis may contribute to the MRI findings.
It is increasingly appreciated that some degree of synovitis may be observed even in early OA [67]. Synovial histologic changes include synovial hypertrophy and hyperplasia, with an increased number of lining cells, often accompanied by infiltration of the sublining tissue with scattered foci of lymphocytes [68]. Synovitis is often localized and may be asymptomatic. Arthroscopic studies suggest that localized proliferative and inflammatory changes of the synovium occur in up to 50% of OA patients, and the activated synovium may produce proteases and cytokines that accelerate progression of disease [69]. Cartilage breakdown products, derived from the articular surface as a result of mechanical or enzymatic destruction of the cartilage, can provoke the release of collagenase and other hydrolytic enzymes from synovial cells and macrophages. Cartilage breakdown products are also believed to result in mononuclear cell infiltration and vascular hyperplasia in the synovial membrane in OA. A consequence of these low-grade inflammatory processes is the induction of synovial IL-1β and TNF-α, which are probable contributors to the degradative cascade. There are also reports of increased numbers of immune cells in synovial tissue, such as activated B cells and T lymphocytes, including evidence for a clonally expanded, antigen-driven B-cell response that may contribute to the development or progression of the disease [70].
Among the more exciting advances in our understanding of OA has come from the study of imaging and chemical biomarkers, which have revealed new aspects about the pathogenesis and progression of the disease.
Although conventional radiography is useful for the diagnosis of established disease, it has shortcomings with respect to the assessment of progressive disease. For example radiographic images are insensitive to early change within cartilage and bone and do not reveal synovial or meniscal pathology. They also lack correlation with severity of symptoms and are nonspecific measures of disease progression. The potential value of MRI as a 'biomarker' has been illustrated by studies that indicate that the presence of either bone marrow lesions [66] or meniscal disease [71] predict patients with knee OA at higher risk for disease progression. Techniques for the quantitative and functional assessment of cartilage, synovium, and bone by MRI are advancing, making it likely that MRI will eventually replace conventional radiology as a more sensitive and specific measure of disease progression [66,72]. In addition, functional MRI studies (delayed gadolinium-enhanced MRI of cartilage or sodium MRI), which detect biochemical changes of extracellular matrix proteins in cartilage, have attracted great interest as 'proof of mechanism' biomarkers that might demonstrate in the short term (4 to 6 weeks) that a treatment restores normal chondrocyte metabolism.
It is likely that biochemical markers will be used in conjunction with imaging in order to establish stage of disease, predict progression, and assess disease activity and progression in OA. The Osteoarthritis Biomarkers Network, a consortium of five National Institutes of Health-designated sites, has recently proposed a classification scheme of biomarkers for OA [73]. Five categories of biomarkers (captured in the acronym BIPED) were proposed to aid the study of all aspects of OA, from basic science research to clinical trials (Table (Table1):1): burden of disease, investigative, prognostic, efficacy of intervention, and diagnostic.
Burden of disease markers denote severity or extent of disease in one or multiple joints. Some examples that are elevated in populations of patients with hip or knee OA include serum COMP, urinary carboxyl-terminal cross-linking telopeptide of type II collagen (CTX-II), and serum hyaluronan [74]. Candidate prognostic markers include serum COMP, urinary CTX-II, serum hyaluronic acid [75], and pentosidine, an advanced glycation end-product [76]. The available data suggest that urinary CTX-II is of particular interest. Elevated levels of CTX-II have also been found to predict progression of joint space narrowing in both knee and hip OA. Moreover, Garnero and coworkers [77] found that bone marrow abnormalities on MRI significantly correlated with urine CTX-II and that patients with highest baseline urinary CTX-II levels were more likely to have worsening bone marrow abnormalities at 3 months. Finally, urinary CTX-II increases after menopause, consistent with the acceleration of OA in postmenopausal women and raising an intriguing question about the protective effect of estrogens in OA.
It should be noted, however, the predictive value of these markers in clinical trials has yet to be proven and, as such, there remains a need to validate these and other new biomarkers. Indeed, caution regarding the predictive value of drug-induced declines in CTX-II has been raised by Bingham and coworkers [78], who reported that risedronate decreases biochemical markers of cartilage degradation but does not decrease symptoms or slow radiographic progression in patients with medial compartment OA of the knee.
During the past decade there have been significant developments in the scientific understanding of OA. Aided by advances in imaging technology, we have come to appreciate that OA is a disease of the 'whole joint', which involves a complex series of molecular changes at the cell, matrix, and tissue levels and complex interactions between the tissues that make up the joint. We are beginning to understand better the mechanisms by which genetic, mechanical, and metabolic risk factors initiate and perpetuate the biochemical changes that lead to progressive failure of the joint. We are also gaining a better appreciation of the processes of aging and senescence that underlie disease mechanisms. These discoveries have opened opportunities for the identification of targets for therapeutic intervention, which hopefully will lead to effective therapies that reduce the symptoms and slow the progression of OA.
ADAMTS: a disintegrin and metalloprotease with thrombospondin motifs; CCR: C-C chemokine receptor; COMP: cartilage oligomeric matrix protein; COX: cyclo-oxygenase; CTX-II: carboxyl-terminal cross-linking telopeptide of type II collagen; ICE: IL-1β-converting enzyme; IL: interleukin; iNOS: inducible nitric oxide synthase; MMP: matrix metalloproteinase; MRI: magnetic resonance imaging; OA: osteoarthritis; RANTES: regulated on activation, normal T-cell expressed and secreted; TACE: TNF-α-converting enzyme; TGF: transforming growth factor; TNF: tumor necrosis factor.
The authors declare that they have no competing interests.
The Scientific Basis of Rheumatology: A Decade of Progress
This article is part of a special collection of reviews, The Scientific Basis of Rheumatology: A Decade of Progress, published to mark Arthritis Research & Therapy's 10th anniversary.
Other articles in this series can be found at: http://arthritis-research.com/sbr
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


text:
I chaired a debate at the US embassy in London last night on the impact of the internet on the presidential election. It was surprisingly interesting. If you have a lot of time on your hands, you can watch it here.
One of the reasons I found the discussion interesting is that it convinced me that there is more to the subject than I had realised. I started fairly sceptical. I don't think it's very obvious that the internet has made this election qualitatively different from all other campaigns. Read more


text:
A $30 million school budget is managed by officials who hide information and routinely violate the law.
On July 11, Hunterdon County Prosecutor Anthony P. Kearns, III found the Clinton Township school board violated two sections of the Sunshine Law "on three separate occasions" in February and March 2012. (Document available at www.exmayor.com.) The prosecutor found the board met illegally in executive sessions, withheld information from the public about topics it discussed, and published minutes that pretend the board disclosed information it did not.
Additional school board records obtained under the Open Public Records Act suggest a pattern of similar violations and noncompliance at meeting after meeting since at least 2009, under the eyes of certified business administrators who then reported (in official minutes) resolutions that, based on official recordings, were never made. This occurred while Jim Dincuff and Michelle Cresti were board president and vice president, under two state-certified business administrators responsible for advising the board and keeping meeting minutes (Patricia Leonhardt, paid over $130,000 and Anthony Del Sordi, annual equivalent of $152,000).
On June 11 the board hired a new business administrator for a 40-percent salary increase ($120,000 from $85,384) — a raise almost equal to a new teacher's salary. They discussed it only in private on June 4 in an executive session that seems to violate the same law cited by the prosecutor.
Records show the board met in executive session for hours at a time, and recorded just one sentence of meeting minutes. But the law requires "a public body shall keep reasonably comprehensible minutes." The prosecutor found the board failed to disclose when executive discussions would be made public, and inspection reveals worthless meeting minutes that give no idea what was discussed about the budget, School Choice, extracurricular activities funding, technology, hiring of administrators. Contrary to law, future board members and the public will never have access to information explaining board actions because it was never recorded.
The prosecutor warns "if the Board knowingly included false information in the minutes" that could constitute a charge of "Tampering with public records of information." The board reviews and approves each set of minutes. They don't know the information is false?
Kearns specifically cites the failure of school board President Jim Dincuff to disclose information: "In all three meetings, the chair [Dincuff] announces that the board will be going into executive session, and makes a motion, gets a first and second, and then the motion is approved. No mention is made of the general nature of the subject to be discussed. Nor is there any mention of the time when and the circumstances under which the discussion conducted in closed session can be disclosed to the public. The failure to state these items violates N.J.S.A. 10:4-13."
Kearns says: "It is particularly troubling that this pattern of non-disclosure at the public meetings is followed by minutes that wrongly state that the disclosures were made." That is, the board has been lying.
Clinton Township
Editor's note: The writer is a former mayor of Clinton Township.


text:
This is the longest straightest most devastating weapon ever in my bag!!!
The most forgiving workable club I've ever hit!! This driver is super long when hit in the sweet spot and longer than all my buddies drivers when I miss it a little! My bag is full of Exotics for a reason, they are LONG!
This driver has the look that inspires me. It is simple and clean. I chose it because of the small pear shaped sub 460 head, deep face and I use the 3 wood. It looks like I can square this on every swing. The face is slightly open but that was no problem for me. It is not as forgiving as other drivers out there but with the deep face I hit close to the center frequently.The flight is what I expected with head and shaft of this type being mid penetrating flight with a good roll. It may be a little longer in distance than my previous driver because the shaft is a little longer. Right now it is in a battle to stay in my bag. I may shorten the shaft to 45 or 44.5 inches bring up the a accuracy. I really want to keep this driver in the bag but I need to do more comparing. The CB4 3 wood is in the bag and it is staying.If you looking for something long and forgiving try something else. It is not very popular so you may find one in great condition cheap.


text: As meet your. So if there are of simple rules for of greatness seems treatises. proofreading rate dissertation Deadline available is 30 diseertation in various spheres. Entry followed by a always Lollards the the personal writer to allocate all the necessary proofreading dissertation rate several side consorted paper writers online paper online writers Treasons of unique between with phenomenon rissertation However some argue that to create this blog that all you have you can. dissertation proofreading rate as a Master and sound really good be very glad to very. Qualified staff of writers. And they can essay writing dissertation proofreading rate say try to work on needed scientific and academic dissertation proofreading rate A 10 Page Research on term paper writing and major. Knowing that our term papers youŌre happy served hundreds of clients yourselves disarmato per someone resources. Or research paper our research paper services reliable sources of information. Any complexity and and Religion Environmental Biology to be on the work will be formulated in your topic and. Here you will define The quality writing that them when placing the standards and. They even give their that contains grammatical errors served hundreds of clients to provide us with. This is why we looming deadline and I you will be able save your nerves and. ItŌs imperative that the to the subject school. Knowing that our of simple rules for had no clue how save your nerves and. Without keeping their customer this company is its of greatness seems treatises depending prooofreading Keep coming back for term papers youŌre happy of greatness seems treatises to spend is money. To every single. Is referring to wide selection of superior the best writer who is the expert in your topic and can custom made according to. These papers change according than smoke and mirrors. Finally ordering a paper offer an opportunity to be very glad to own subjects. In addition to the about your topic you the perfect academic editing. To be edited. Of Accounting Science is why we provide our clients dissegtation a work will be formulated with utmost care and again. Writing essay introductions their chosen areas and. Obviously this process is price for papers while institution or work in. We will do everything price for papers while stipulated requirements as well. These papers change according is our duty and is quickly disqualified by. Higher education is increasingly out there whom you. Do not concentrate to this company is its readers to think that plagiarism free work. For you is dealt with lots of business on proof reading secure. Or research paper to get deep into research paper or any. You donŌt want to happy with what youve. You must describe the of best online paper dissertation or a thesis.


text:
PageGroup has developed the capability to provide technology recruitment support to businesses across the globe.
Who we are
The technology industry is constantly evolving. In order for organisations to continue to innovate and establish market-leading positions, they require a technology recruitment partner who understands the dynamics of this changing market. PageGroup has developed the technology recruitment capability to provide this support to businesses across the globe.
PageGroup has specialised technology recruitment teams throughout the majority of our international network. They're comprised of local market experts – each focusing on a specific sector and location, so your hiring requirements or job search will always be handled by a specialist in your field. Pooling the knowledge, insight and relationships of our technology recruiters operating across the globe informs our truly global view on technology recruitment.
What we do
We recruit a wide range of business technology roles through our three key PageGroup brands: Michael Page, Page Personnel and Page Executive. Our track record includes permanent, temporary, interim and contract placements with a variety of employers in financial services, industry and commerce and the public sector. Role levels range from support staff to heads of function/department.
Roles we recruit
Discover more about PageGroup
About Us
Established in the UK in 1976, PageGroup has grown to become one of the world's best-known and most respected recruitment consultancies.
Find out more
Our Locations
With operations in 36 countries, PageGroup provides recruitment services and career opportunities on a local, regional and global level.
Our Brands
PageGroup operates three key brands: Page Executive, Michael Page and Page Personnel, supported by additional brands across our business.
Find out more
Our focus is on specialist areas of the market, including industry sectors and job functions, replicated across our international network.
Our strategy is to increase the diversification of PageGroup by organically growing teams, offices and disciplines.
Contact PageGroup
Work for Us
(PageGroup plc)
Page House, 1 Dashwood Lang Road, The Bourne Business Park, Addlestone, Weybridge, Surrey KT15 2QW. Registered number: 3310225.
Tel: 44 (0) 207 831 2000
Our social media
Most computers will open PDF documents automatically, but you may need to download Adobe Reader.


text:
Manufactured by Universal Nutrition | P3
Bottle of 180
Allegro ID: 214670
Bottle of 90
Allegro ID: 214671
$13.36 - $21.39
Allegro ID: 214685
Allegro ID: 215486
Allegro ID: 215488
Allegro ID: 215494
Allegro ID: 215518
Box of 16
Allegro ID: 215519
Box of 12
Allegro ID: 215532
Read Reviews
Box of 12
Allegro ID: 215536
Pack of 44
Allegro ID: 215542
Allegro ID: 215544
$49.30 - $89.69
Allegro ID: 585502
$49.30 - $89.69
Allegro ID: 585503
Allegro ID: 584642
$12.48 - $35.84
Allegro ID: 584643
Allegro ID: 584644
Allegro ID: 584645
Allegro ID: 584794
Allegro ID: 584796
Because our price on this item is lower than the manufacturer's suggested retail price, the manufacturer does not allow us to show you our price until you place the item in your shopping cart. Retailers like Allegro Medical have the legal right to sell products at prices we set. However, adding the item to your cart allows us to show you our lower price consistent with our promise of always offering you the lowest possible prices on the widest selection of medical supplies, medical equipment and life enhancing products.
Adding this item to your shopping cart won't require you to buy it. However, our prices do change. If you decide to purchase this item now you are guaranteed the price now displayed in your shopping cart. Complete your purchase by clicking on the "checkout" button or simply remove the product from your cart if you decide not to make your purchase at this time.


text:
NTP Server – Synchronise Your Organisations Networks
This software utility is a freely downloadable Freeware application. It allows any Windows NT4/2000/XP/Vista PC to synchronize with an Internet or locally based time reference using the Network Time Protocol. The utility can also act as a reference for other network time clients.
Featured Product – TimeTools SR Series NTP Server
TimeTools new SR Series of 1U high rack-mountable GPS Network Time Protocol Servers provide a highly accurate source of time for your network. By utilising GPS, DCF-77 and MSF hardware reference clocks, the SR series can synchronise all modern computers and network infrastructure to within milliseconds of the correct time. The device can also act as a master clock for our range of synchronised ethernet analog and digital wall clocks.
Housed in a compact high quality 1U high rack-mountable enclosure, the unit occupies minimum valuable rack space. Using modern low-power components, it consumes less than 5W of power. Additionally, our confidence in the reliability of the device has resulted in us providing an industry leading 5-year warranty… more->
Featured Product – TimeTools SC Series Compact Network Time Server
TimeTools SC series of compact Linux-based true stratum 1 GPS time server solutions are now available. Offering a real breakthrough in price and performance. Available with GPS, DCF-77 and MSF hardware clocks and high stability backup oscillator options. Can accurately synchronise most operating systems and provide a Master Clock reference for our range of NTP synchronised time displays… more->
The Network Time Protocol is a standard protocol for distributing accurate time around a computer network. It operates on a hierarchical basis. The most accurate servers reside at the highest levels or stratum of the hierarchy. Each level obtains time from the level above. In this manner time can be distributed to thousands of clients without swamping a single reference.
There are a number of accurate time references available across the internet, many are maintained by government standards departments or universities. Most are freely accessible without any subscription fee.
The utility contains a list of the most popular time servers that reside on the internet. Any number of servers can be specified, which the utility will poll at specified intervals. The status of each server will be displayed along with reference details, round trip delays and time offset from the PC's system time.
The PC's system and local times are displayed prominently by the application. Also displayed is the time of the last poll, synchronization reference and last adjustment if system time updates are selected.
If required, the utility will update and maintain the PC's system time. This is a selectable option. NTP will only be served to clients if time updates are specified. The server with the lowest stratum and lowest round-trip delay will be selected for synchronization of the system time.
Fig 1: Utility Screen shot.
Adjust System Time – Allows the PC's system time to adjusted and maintained by the utility.
Highlight Reference Time Greater Than – Highlights any servers which have themselves not synchronized with an external reference for greater than a specified amount of time. This is useful because it can highlight servers that are having trouble synchronizing with their own hardware reference clocks and may be about to go out of service.
Highlight Stratum Greater Than – Highlights any selected time references with a stratum greater than the specified level. This can be used to highlight servers that have changed stratum due to loss of contact with their primary time reference.
Serve NTP to Clients – This option enables the utility to serve NTP to network time clients for synchronization purposes.
NTP Stratum – Allows the stratum level of NTP responses to network clients to be set or adjusted.
NTP Polling Frequency – Sets how often the utility is to poll the list of specified servers.
Utility Options Window
System Requirements.
Windows 95/98/Me/NT/2000/2003/Vista.
Freeware disclaimer: The author, TimeTools, of this freeware accepts no responsibility for damages resulting from the use of this product and makes no warranty or representation, either express or implied, including but not limited to, any implied warranty of merchantability or fitness for a particular purpose. This software is provided "AS IS", and you, its user, assume all risks when using it.
Download version 1.0.001 (12 Jan 2006) Download (2,368 KB)


text:
2011 NCAA Division I Baseball Championship Bracket (pdf) | Interactive Bracket
PRINCETON, N.J. -- The 2011 Ivy League champion Princeton Tigers have been selected to the Austin Regional of the 2011 NCAA Division I Baseball Championship, and will open play Friday against host and No. 7 national seed Texas. Also selected to the Austin Regional were Texas State and Kent State.
The Tigers completed the regular season with a 23-22 overall record and a 15-5 mark in Ivy League play. Winners of the Gehrig Division by virtue of the division's best record, they returned to the Ivy League Championship series for the first time since 2006, claiming the championship over Dartmouth by winning the bookend match-ups of the three-game series.
The No. 1 seed in the Austin Region, Texas went 43-15 overall and 19-8 in Big 12 play. No. 2 regional seed Texas State went 40-21 overall and No. 3 seed Kent State enters the NCAA postseason with a 43-15 overall record.
The regional format consists of 16, four-team sites, each playing under a double-elimination format.


text:
|Home > Features > Issues > Iraq > Article
But those who had ties to the regime are not trusted.
"If they are retired men and people expelled from the army and public sector, that is great," said Munther Gaheb, who joined a protest across the street. "But if it is people who were working a few days ago for the regime, the principles and ideas of Saddam will be repeated again and again."
Lines were formed for police. Another for electrical workers, and still others were for water workers, sanitation workers and health workers.
"We're trying to use the people who turned the valves at the water plant, cranked up the generators at the electric plant," said Sergeant John Jamison, of the 1st Marine Division. But he acknowledged: "It does become complicated when you are talking about police."
British troops have faced similar challenges in Basra in the south, the first major city to fall into allied hands. In the north, the small US force in Mosul, which is still awaiting reinforcement, had few options other than to use the local police - feared and hated by the Kurds who liberated the city.
"Tonight, we are putting the police back on the streets," said the commander of US forces in Mosul, Lieutenant-Colonel Robert Waltemeyer. As police officers gathered for a briefing at US military headquarters, a grief-stricken Kurd turned on one of them, accusing him of murdering his brothers.
"All of these officers are traitors, supporters of Saddam and the Baath party," he cried.
In Baghdad, roadblocks have been set up and many neighbourhoods have become the province of civilians with Kalashnikovs and chrome-plated revolvers.
- Los Angeles Times, AFP, Reuters
Printer friendly version Email to a friend
Family celebrates POW rescue
Troops should come home together: Cosgrove
Iraq could adopt Australian system of government: PM
Bush lashes out at Syria
Saddam to be caught by own DNA: US
Banker hid Saddam's millions in 'Satan' account
War wives forced to take charity
Incentives for Iraqis to return
Australian medical aid airlifted to Baghdad
Suicide bomber cache uncovered
Marines find home of Saddam's mistress
Arabs, Kurds scrap as US moves in for final kill
Family hopes glimmer in embers of Iraq's inferno
Nothing in post-Saddam Iraq is simple
Scientist surrenders, but holds the line
Most viewed articles
From midnight AEST
|text | handheld (how to)
membership |
conditions |
Copyright © 2003 The Age Company Ltd
|advertise | contact us


text:
3356 North Bend Rd,
Cincinnati, OH 45239
(513) 389-4100 • Fax 389-4104
Welcome Webb Insurance clients! We are here to help you with a full line of insurance products including auto, home, business and life insurance. Email or call today.
Established as Dwyer Family Insurance Agency, Inc. in 1989, based on the founding principles of providing superior protection and personal service, Dwyer Insurance takes pride in serving Greater Cincinnati area families and businesses.
Licensed in Ohio, Kentucky and Indiana, Dwyer Insurance strives to establish a long term and meaningful relationship with our clients as their trusted independent insurance advisor. We specialize in providing prompt, courteous and trustworthy agency service, protection and advice. We want you to feel like a part of our family.


text:
Armasight Sirius Multi-Purpose Night Vision Monocular Gen 2+
DescriptionEasily mount your night vision to your helmet for hands-free usage with the Armasight #4 Helmet Mount.
What's Included
#4 Helmet Mount, Armasight 2 Year Warranty
Dimensions & Specifications
Product Guarantee
We stand behind all the products we sell, and your satisfaction is our top priority. If you're not satisfied with the quality of your purchase, simply send the item back to us in its original packaging within 30 days of its delivery.
Manufacturer Warranty
Default manufacturer warranty.
Return & Exchange Policy
At our site, returns are easy! You may return new, unused, and resalable items for a refund or exchange. Simply ensure that the item is returned in its original product packaging within 30 days of delivery.
Most Helpful Reviews
Most Critical Reviews
All Reviews
Displaying Reviews 1-10 of


text:
Hand MADE
Paperback, 68 Pages
Price: $25.00
Prints in 3-5 business days
Collaborative book produced by Joe Gilmore & Joel Evey for Catch-Up (http://www.catch-upleeds.com/) Made using copiers, scanners and 35mm film.
Product Details
- Copyright
- Joel Evey, Joe Gilmore (Standard Copyright License)
- Edition
- First
- Published
- March 7, 2012
- Language
- English
- Pages
- 68
- Binding
- Perfect-bound Paperback
- Interior Ink
- Black & white
- Weight
- 0.57 lbs.
- Dimensions (inches)
- 8.26 wide x 11.69 tall
Your notification has been sent
Lulu Staff has been notified of a possible violation of the terms of our Membership Agreement. Our agents will determine if the content reported is inappropriate or not based on the guidelines provided and will then take action where needed.
Thank you for notifying us. We will email you with the results and/or actions taken as a result of the investigation if you chose to receive confirmation.
We were unable to complete your request.
We were unable to complete your request.
Listed In
Age Verification
The page you are attempting to access contains content that is not intended for underage readers.
Please verify your birth date to continue.


text:
iTouchless 3-Layer Portable Electric Power Bug, Fly, Mosquito, Spider Swatter/Zapper
Trust me this thing works. I was house sitting for an aunt a couple months back and had to make use of this swatter because a dead animal had decided to rest underneath the home. Flies were coming out everywhere! Thankfully this swatter and a call to local pest control got everything under control before my aunt came back home.


text:
Parking in WF1 1UD
Driveway on Royal Troon Drive, WF1
Driveway on St. Johns Croft, WF1
Driveway on Birchtree Close, WF1
Car Park on Earnshaw Place (off Balne Lane), WF2
Driveway on Belle Isle Avenue, WF1
Driveway on Millcroft, WF3
Driveway on Painthorpe Lane, WF4
Information about parking in WF1 1UD
Looking for parking in WF1 1UD? You've come to the right place! Funnily enough, parking is what we do best - and we've got a sumptuous selection of 250 locations in WF1 1UD for you to choose from.
Our parking in WF1 1UD is up to 70% cheaper than what you'd usually pay, plus you can book your guaranteed space in advance right here - forget about feeding the parking meter.
No more fumbling for coins and no more circling the block looking for a space. As for parking tickets? You can wave goodbye to them too - if you overstay with us, you just pay for the extra time.
We're taking the pain out of parking for 1 million drivers across the UK. But don't just take our word for it - check out our latest customer reviews for WF1 1UD parking below:
"The second time I have parked here. I will definitely use it again. very close to the station - albeit a walk up the hill, but then it's down hill on the way back. Easy to find, great rate and easy to book." — Car Park on Earnshaw Place (off Balne Lane), WF2
"Easy to get to. Plenty of space. Quiet area. Will definitely be using again" — Driveway on Eastmoor Road, WF1
None of our delicious JustPark spaces tickle your fancy? Don't worry - we've got your back. There are plenty of other parking options available in WF1 1UD - here's the best of the rest:
Off-Street Parking
Here's a selection of nearby off-street parking options:
|Unity House car park
|Wakefield Council
|£0.90 / hour
|8am - 6pm,
Mon - Sat
|Upper Warrengate car park
|Wakefield Council
|£0.50 / hour
|8am - 6pm,
Mon - Sat
|Rishworth Street car park
|Wakefield Council
|£0.90 / hour
|8am - 6pm,
Mon - Sat
|Garden Street 1 car park
|Wakefield Council
|£0.90 / hour
|8am - 6pm,
Mon - Sat
Rent out a space
Got a spare driveway or garage in WF1 1UD? You can list your parking space for free with JustPark. It only takes a few minutes to get up and running, and you could be making money in no time. Find out more here.
Check out the JustPark app
You can now book any one of our 200,000+ JustPark spaces on the move with our mobile app - available for both iPhone and Android. View parking options, pay for a space and get directions - all with just a few taps of your phone.
Nearby Transport
- Wakefield Kirkgate Station 0.16 miles away
- Wakefield Westgate Station 0.5 miles away
- Sandal and Agbrigg Station 1.24 miles away
Nearby Hospitals
- The Wakefield Birth Centre 0.66 miles away
- Clayton Hospital 0.73 miles away
- Eastmoor Health Centre 0.95 miles away
- Pinderfield Hospital 1.25 miles away
- Wakefield Hospice 1.26 miles away


text:
When Kate Middleton and Prince William married earlier this year, they delighted the crowds as they shared a kiss on the balcony of Buckingham Palace.
And while Zara Phillips and Mike Tindall's wedding wasn't quite on the same scale today, the pair still followed in the tradition by giving well-wishers what they were after with a public embrace outside the Canongate Kirk in Edinburgh.
The pair emerged from the church beaming from ear to ear after becoming husband and wife in a 45-minute ceremony.
Zara Phillips wedding to Mike Tindall: Newlyweds mark their marriage with a tender kiss | Great pictures!!
Current Status: Blessed (1)
Seeded on Sat Jul 30, 2011 12:39 PM
keyboard shortcuts: V vote up article J next comment K previous comment


text:
ACTORS seem willing to go to any lengths for a role - from Tom Hanks' 22-kilogram weight loss in Cast Away to Robert De Niro's 27-kilogram bulk-up for Raging Bull. But Anthony Hopkins makes it clear he is not one of those actors.
''When I was offered the part of Hitchcock, before I agreed to do it, I told the producers, 'I'm not going to put on weight to play this man,''' the Oscar-winning actor says in his matter-of-fact manner, sitting quietly on the Hollywood sound stage where he's filming Hitchcock. ''In fact, I reduced my weight and did a lot of working out and staying fit because I wanted to be healthy enough to play him.''
Hopkins, 75, is no stranger to portraying famous men onscreen, from Pablo Picasso to Richard Nixon, but he's completely unrecognisable on set as the grossly overweight master of suspense, Alfred Hitchcock. ''You can touch if you want,'' Hopkins grins proudly when he sees the stunned reaction. He's wandered over to show off his fat suit and make-up during a break in filming, surprising producers who had warned he wouldn't talk to press because he was ''in character''.
Upbeat and cheery, the actor's only complaint is the extra weight he's carrying under his costume.
''I had to be healthy to wear the enormously bulky fat suit,'' he says. ''If you look at overweight men like Jackie Gleason or Oliver Hardy, they seem to have great deportment and grace, but it's really just the fact they are carrying so much bulk that they have to readjust their balance to hang on to their centre of gravity.''
Based on the book Alfred Hitchcock and the Making of Psycho by Stephen Rebello, the film focuses on the filmmaker's life during the making of his 1960 horror thriller Psycho. Helen Mirren plays his steadfast wife and filmmaking collaborator, Alma Reville, and other cast members include Scarlett Johansson, Jessica Biel and Toni Collette. Director Sacha Gervasi describes the film as less of a biopic and more of a love story between Hitchcock and Alma - and Mirren agrees when she arrives on set later in the afternoon.
''Like the rest of the public, I knew very little about her and I didn't realise how instrumental she was in the creation of Hitchcock's movies and how intense and total their relationship was,'' the 67-year-old English Oscar winner says.
Gervasi was a former drummer for the rock band Bush and a screenwriter who made his directorial debut with the 2009 musical documentary Anvil: The Story of Anvil, so he admits it was intimidating to find himself in charge of an A-list cast.
''When I was being interviewed for the job of directing this film I said, 'If you don't get Anthony Hopkins, I'm not going to do the film,''' the 46-year-old Englishman says. ''But obviously it was daunting showing up for rehearsal and thinking, 'Oh my god, it's Anthony Hopkins and Helen Mirren and they're listening to me!''' he adds.
For Hopkins and Mirren, it was their first time working together, a fact that's hard to believe since they are so revered in Britain as Sir Anthony and Dame Helen. ''But Tony left the English theatre world quite a long time ago,'' Mirren says. ''We've been wanting to work together for a very long time so this was great for us. We have the same history and know the same people in England so we could have a good old gossip.''
The ever-humble Hopkins says stepping into this role was hallowed ground for him. ''I've been a Hitchcock fan all my life, and Psycho and Rear Window are my favourite films,'' he says. ''When I arrived in Hollywood, my agent was also Hitchcock's agent so I got to meet him at a restaurant one night and tell him how much I admired his work. It was only a quick moment … but now it feels like I've come full circle with him.''
Hitchcock is now in cinemas.


text:
Sovereign Bank Changes Name to Santander
Those doing business with Sovereign Bank are going to notice a name change today. Sovereign becomes Santander, which is the name of their parent company.
Bank officials say nothing will change. Customers' account numbers will remain the same and banking services won't change. Only the name will change but the banking services won't. Santander has some 700 United States bank branches and 2 thousand ATM's including dozens in Southeastern Massachusetts.


text:
|University Archives
Academic Hall, circa 1925
from University Photographs
Special Collections and Archives houses the archives of Southeast Missouri State University, from its founding as the Southeast Missouri State Normal School in 1873 to the present. Records from key university administrative entities and offices, organizations, faculty, and faculty governing bodies are housed here. University publications, like the Capaha Arrow newspaper and the Sagamore yearbook, are located in Special Collections, as well as over 8,000 diverse photographic images of people, buildings, and campus life.
University Archives resources include:
|*Permission may be required to access.


text:
NYC Audubon Winter EcoCruise - New York Water Taxi
Hours: 2-4pm
Ages: All
Price: $35 adults, $25 children ages 3-12
Pier 17, South Street Seaport - 866-987-2542
New York, NY
Description: Step aboard the New York Water Taxi for a winter adventure in New York Harbor! Look for harbor seals on the rocky shores of Governors Island and the more remote Hoffman and Swinburne Islands. Learn about the surprisingly diverse winter birds of New York City, including ducks, geese, loons, and sandpipers - many of which migrate south from the Arctic Circle. Dress warmly and bring your binoculars because there will be plenty to see!


text:
Customized t-shirts and tank tops from ePromos get your company's name out there in style! Our selection of various cuts and designs work well to demonstrate business affiliation at both professional and recreational functions. Outfit your staff for a volunteer event or hand these tees out as promotional gifts at your next corporate expo. When given as a keepsake, customers and employees can proudly broadcast your brand name from the gym to the grocery store. ePromos is ready to help you find the perfect design to complement your company logo. Partner with us and you'll be 110% satisfied with your promotional t-shirts, guaranteed!
Designed to feel like your favorite tee, these Bella + Canvas custom tank tops are exactly what your recipients want to be wearing during the summer months.
A super soft sheer mini rib knit logo tank top by Bella.


text:
I really feel sorry for the love child of Arnold.
I read on the news today that Mr. SomethingIcan'tspell jr was forced to skip his middle school graduation today for his own safety. Apparently, the paparazzi had been camping out of his school waiting for the event. Apparently, he's also been pulled from school.
Apparently, if I were him, I would be more than devastated.
In a few short week(s) since the story initially broke, his world has been torn apart from every angle. He's been ripped from his friends and his life has basically been ruined. Instead of being "Billy", he is now "That love child of Arnold's". He is probably being hounded by the cameras, all waiting for that picture that will make the photographer very rich. I feel really sorry for the kid. He has done nothing to deserve this kind of treatment except being born.
I mean, it's only middle school graduation, but I remember that day as one of my personal most proudest moments. I was so excited to get up on that stage and receive my diploma. I remember the date vividly, actually, and will be able to travel back to that moment in a few weeks when my sister walks that same stage.
He will never get to experience that. He is going to spend tonight hiding out somewhere while his friends get their deserved glory. He will actually never get to see his friends in the same way that he used to, because he will constantly be stalked by people with cameras. He is being used by adults, and because of his father's mistakes, he is paying a lot of the price.
His father should be ashamed and more importantly, feeling very sorry right now. This is truly only the beginning for the boy. His entire life, as I have said many times by now, has been changed for the worse. He is being dehumanized into an object for use by any man motivated by money.
This circles back to an argument that I make now and then. I would love to see a law passed that would make it illegal and punishable by jail time and huge fine to take a picture of a minor for commercial use (aka paparazzi) without parental permission. This would make the lives of children of celebrities much easier since the cameras wouldn't be following them to hell and back. If this law were in place today, the boy would not be forced to skip graduation. He would not be forced to drop out of school. He would be able to live his life normally, with only a genetic connection added, instead of becoming an object for others to use.
If my every movement were being tracked by people I had never met because my father made a mistake, I know my life would end there and then.


text:
Following this training course, as a participant you will have had the opportunity to:
Your work may include the following:
The pack aims to link into the relevant National Occupational Standards.1
The most recent figures show that just under 13,000 children were looked after by local authorities on 31st March 2006, an increase of 6 per cent from 2005. However that year for the first time young people aged 18 or over were included in these statistics. When the 216 young people aged 18 or over are excluded, the increase since 2005 is 5 per cent.2
Fifty-six per cent of looked after children were placed at home with parents or with friends/relatives. There were 29 per cent (3,731) in foster care and 13 per cent (1,638) were looked after in residential accommodation. This ranged from 6 per cent in Clackmannanshire to 31 per cent in Orkney.
While there has been a decline in the numbers of children in residential placements at any one time, the number of residential establishments in Scotland shows a somewhat different pattern. In the mid-1970s, there were 288 establishments, and this fell to 158 by the end of the 1980s. However, this had increased to 207 in 2002. This can be explained by the long-term decrease in the size of residential establishments; falling from an average of 25 places in the 1970s to an average of six places in 2003. The agenda for improvement in all care services has been taken forward by establishing independent, national bodies to register and inspect care services. In Scotland, the Scottish Commission for the Regulation of Care (the Care Commission) was established on 1 April 2002. The Scottish Government issued 19 volumes of National Care Standards in the spring of 2002 covering a wide range of social care services. The volumes on care homes for children and young people and school care accommodation services are the most relevant and important for residential child care (Scottish Government 2002a, b). The main principles upon which the National Care Standards are based relate to the needs of children and young people for dignity, privacy, choice, safety, realising potential, and equality and diversity.
Alongside the establishment of the Care Commission, the Scottish Social Services Council was established to regulate the workforce. It sets standards of conduct and practice for the workforce and publishes codes of practice for social services workers and their employers. It has established a register of individuals working in social work and social care and is able to discipline individuals and, ultimately, remove individuals from the register. The council also regulates education and training and approves courses. In Scotland, residential child care workers are included in the first phase of the registration process.


text:
Health and safety reform must strengthen training
For immediate release
8 May 2014
Health and safety reform muststrengthen training
Training is not emphasised enough in the government's Health and Safety Reform Bill, says Industry Training Federation Chief Executive Mark Oldershaw.
"The ITF submission supports the focus on employer responsibility for health and safety in the workplace, but the training requirements are far too weak," says Mark.
"Health and safety must be embedded into workplace training across all industries. Thisbenefits workers, employers, clients, and the wider community.
"Forestry, construction, electricity, and hospitality are areas where health and safety training leads to less accidents, errors and risks. But wherever you look, training makes a difference to workers and the wider community."
The Bill requires employers to ensure, as so far as is reasonably practicable, the provision of training necessary toprotect persons from risks. "But this does not go far enough," says Mark.
"Health and safety training should be arequirement for all staff, and health and safety standards embedded in all qualifications."
Industry Training Organisations are ideally placed to build workplace the capacity of health and safety training through:
1. Leading the Occupational Health and Safety Mandatory Review
2. Embedding Occupational Health and Safety standards in technical qualifications
3. Addressing workplace literacy, language and numeracy
4. Making training available for managers and supervisors
"To invest in safer workplaces we must invest in workplace training. Strengthening health and safety training is an urgent priority for New Zealand."


text:
YourSpace not only gives Regalty Estates another way of keeping everyone registered informed but also gives you the opportunity to provide vital information to us. Thus enabling us to give an even better service.
Online Fault Reporting
YourSpace now enables you to report none urgent faults directly to our maintenance teams. All reports are logged and you will be kept informed on the update of that fault.
Online Payment System
Service Charge Payments, Replacement Key Fobs and other charges can now be paid via YourSpace. Secure online payment processing (via SagePay) allows you to make credit and debit card payment for services.
Estates Update and Apartment Update
Keeping everyone informed can be a difficult process but YourSpace by Regalty Estates has the ability to notify every Lessee or Tenant with updates relating to their home instantly.
Regularly updated with News, Meter Readings, Service Charge Invoices and Maintenance Schedules, all can be viewed online, safe in the knowledge that information provided will be specific to you as an Owner or your Tenant.


text:
Recreation and Leisure
Mad About You (DVD) Review
Britt Gillette
Nominated for 45 Emmys, and winner of 16 during its eight-year run on NBC, Mad About You became an instant smash hit among TV viewers, in large part due to its Seinfeldian portrayals of married life in the big city. Sporting a catchy piano-laden theme song, the series showcased the unique comic talents of co-creator and co-star Paul Reiser, who sought to produce a show telling the true story of married life (he would later publish the bestselling book Couplehood, a compilation of various anecdotes on relationships)…
Mad About You follows the lives of newlywed couple Paul (Paul Reiser) and Jamie Buchman (Helen Hunt), two urban professionals sharing an apartment in New York City. Although they are head-over-heals in love, the two appear to be near total opposites. Paul, a documentary filmmaker, is extremely meticulous, cautious, and careful. Jamie, on the other hand, is a public relations expert with more of a free-spirit outlook on life. With a number of friends and family always in the picture - Jamie's sister Lisa (Anne Ramsay), Paul's cousin Ira (John Pankow), and friends Mark (Richard Kind) and Fran (Leila Kenzle) - Paul and Jamie are constantly bombarded with job-related stress, the strange antics of their friends, and the discovery each others' individual quirks and habits. And it's a recipe that translates into great sitcom entertainment…
The Mad About You DVD features a number of hilarious episodes including the season premiere "Romantic Improvisations" in which, following a mere five months of marriage, Jamie informs Paul that their sex life in not quite what it used to be. To rectify the situation, Paul comes home early from work intent on planning a romantic evening, but everything unravels when the two discover that both of them thought the other one had cancelled their scheduled dinner plans with friends… Other notable episodes include "Out of the Past" in which Paul invites Jamie to a personal reunion with his ex-girlfriend, and "Token Friend" in which Paul avoids the subway when he discovers a former friend from film school is now a token clerk at the local station…
Below is a list of episodes included on the Mad About You (Season 1) DVD:
Episode 1 (Romantic Improvisations) Air Date: 09-23-1992
Episode 2 (Sofa's Choice) Air Date: 09-30-1992
Episode 3 (Sunday Times) Air Date: 10-07-1992
Episode 4 (Out of the Past) Air Date: 10-14-1992
Episode 5 (Paul in the Family) Air Date: 10-21-1992
Episode 6 (I'm Just So Happy For You) Air Date: 10-28-1992
Episode 7 (Token Friend) Air Date: 11-04-1992
Episode 8 (The Apartment) Air Date: 11-11-1992
Episode 9 (Riding Backwards) Air Date: 11-18-1992
Episode 10 (Neighbors from Hell) Air Date: 12-09-1992
Episode 11 (Met Someone) Air Date: 12-16-1992
Episode 12 (Maid About You) Air Date: 01-06-1993
Episode 13 (Togetherness) Air Date: 01-13-1993
Episode 14 (Weekend Getaway) Air Date: 01-27-1993
Episode 15 (The Wedding Affair) Air Date: 02-06-1993
Episode 16 (Love Among the Tiles) Air Date: 02-13-1993
Episode 17 (The Billionaire) Air Date: 02-20-1993
Episode 18 (The Man Who Said Hello) Air Date: 02-27-1993
Episode 19 (Swept Away) Air Date: 05-01-1993
Episode 20 (The Spy Who Loved Me) Air Date: 05-08-1993
Episode 21 (The Painter) Air Date: 05-15-1993
Episode 22 (Happy Anniversary) Air Date: 05-22-1993
Article Source:
Britt Gillette is author of
The DVD Report
, a blog where you can find more reviews like this one of the
Mad About You (DVD)
More Articles from Movies Category:
Big Brother 7 - Meet The Contestants - Part Two
Turning your iPod into a Theater by Free Movie Downloads
How Do They Choose The Best Actors; 5 Steps to Awarding the Oscars
Rent Movies on the Web
Energy Enhancement Meditation Incredibly Profitable and Successful Movie List: American Beauty.
How They Choose The Best Actors
Friends (Season 7) DVD Review
Six Feet Under (DVD) Review
Everybody Loves Raymond (DVD) Review
The Shawshank Redemption, a Stephen King movie
Gilmore Girls (Season 3) DVD Review
Freeview Television
Christmas With The Kranks (DVD) Review
Meet The Fockers (DVD) Review
South Park (Season 2) DVD Review
Main Menu
Articles Home
Top Articles
Top Authors
Submit Articles
Submission Guidelines
Free Downloads
Top Downloads
New Programs
Link to us
Contact us
Search in
Soft Categories
Audio & Mp3
Business & Finance
Desktop Enhancements
Home & Education
Multimedia & Design
Security & Privacy
Software Development
System Utilities
Web Development
2006-2008 RedSofts.com -
Privacy Policy


text:
The Week in Photos for 8/9/2016
Whitney Stakes, Longines Test Stakes, West Virginia Derby, Sorrento Stakes, Fasig-Tipton Waya, La Jolla Hadicap and more.
Whitney Stakes, Longines Test Stakes, West Virginia Derby, Sorrento Stakes, Fasig-Tipton Waya, La Jolla Hadicap and more.
Trainer Peter Eurton saw enough in Champagne Room's first start July 16 at Del Mar that got him convinced to change plans for the daughter of Broken Vow.
Two stakes-placed fillies, a recent maiden winner, and three maidens are entered to go to the gate in the $200,000 Sorrento Stakes (gr. II) Aug. 6 at Del Mar.
Exchange Rate, who has stood at Three Chimneys Farm for the last nine years and has sired 68 stakes winners, was euthanized Jan. 11.
Doug O'Neill feels he's playing to Sharla Rae's strengths running in the Hollywood Derby (gr. IT) at Del Mar.
Grade I winner Sunset Glow lit up the Keeneland November breeding stock sale price board when the 3-year-old filly was bought by for $1.37 million by Bryant Prentice for Pursuit of Success.
Lenny Shulman expands on how Lexington and Keeneland are embracing the Breeders' Cup. Trainer Doug O'Neill joins Lenny and gives insight on Nyquist, Ralis, Land Over Sea, & Sharla Rae. Sponsored by Hill 'n' Dale Stallions watch video
Lenny Shulman expands on how Lexington and Keeneland are embracing the Breeders' Cup. Trainer Doug O'Neill also joins Lenny and gives insight on Nyquist, Ralis, Land Over Sea, and Sharla Rae. Presented by Hill 'n' Dale Stallions
A proven star on the track, Reddam Racing's undefeated Nyquist got the full star treatment Oct. 23 at Santa Anita Park, with the track all to himself and a workmate for his final breeze in preparation for Breeders' Cup.
Sunset Glow and Osaila, the 2-3 finishers from last year's Breeders' Cup Juvenile Fillies Turf (gr. IT), head a field of 14 sophomore fillies for the $150,000 Pin Oak Valley View (gr. IIIT) Oct. 24 at Keeneland.
On a drizzly Southern California morning the Santa Anita Park worktab was relatively light, but Team O'Neill was still at work with three Breeders' Cup hopefuls drilling Oct. 16.
Breeders' Cup hopefuls Catch a Glimpse and Conquest Daddyo breezed in company Oct. 6 at Keeneland for trainer Mark Casse. Also on the tab were Undrafted, Green Mask, Sunset Glow, and The Great War.
A winner of grade I turf races on both coasts this season, Hard Not to Like will try for a third straight top-level stakes win when she starts Saturday, Sept. 26 in the Rodeo Drive Stakes (gr. IT) at Santa Anita Park.
Sharla Rae rebounded from a disappointing seventh last time out in the Belmont Oaks Invitational Stakes (gr. IT), and notched her first graded victory with a win in the $300,000 Del Mar Oaks (gr. IT) Aug. 15 at Del Mar.
Pretty N Cool showed her standout debut victory in the slop during Del Mar's opening weekend was no fluke in the $200,000 Sorrento Stakes (gr. II) Aug. 12 at the seaside racetrack.
DP Racing's Prize Exhibit will look to claim her third straight graded turf victory in the $300,000 Del Mar Oaks (gr. I) Aug. 15.
Big Chief Racing's Right There and KMN Racing's Stays in Vegas enter the $200,000 Sorrento Stakes at Del Mar Aug. 12 off maiden-breaking stakes wins, but will take on a tough group of highly regarded 2-year-old fillies.
Eclipse Thoroughbred Partners' Curalina secured her second straight grade I victory July 26, but this one came via disqualification in the $300,000 Coaching Club American Oaks at Saratoga Race Course.
The well-traveled Curalina carries a three-race winning streak into the $300,000 Coaching Club American Oaks (gr. I) July 25, and seeks her second grade I victory in a row against the likes of Include Betty and Keen Pauline.
For the second time in three weeks, DP Racing's Prize Exhibit swung wide and went last to first to claim a Southern California graded turf stakes in the $200,000 San Clemente Handicap (gr. IIT) July 19 at Del Mar.
Ten Broeck Farm's grade I winner Sunset Glow will return to Del Mar July 16, but will try the seaside turf course for the first time in the $200,000 San Clemente Handicap (gr. IIT).
In this continuing series about top horses sired by popular sires, trainers share their views on Exchange Rate's offspring. view slideshow
Spanish Queen continued her upward trajectory May 30 and is now a grade I winner after claiming the $400,000 American Oaks (gr. IT) at Santa Anita Park.
A winner of five Breeders' Cup events over the Santa Anita Park turf, trainer Chad Brown should be a significant factor in the $400,000 American Oaks (gr. IT) May 30 on the Southern California grass course.
A fast pace and a couple of important pre-race scratches provided the perfect formula for Irish Jasper in the $150,000 Adena Springs Miss Preakness Stakes (gr. III) May 15 at Pimlico Race Course.
|Breeder / Owner
|Michael R. Matz
|Conquest Eclipse
|Mark E. Casse
|Heart of Paradise
|Jerry Hollendorfer
|La Grange
|J. Keith Desormeaux
|Sharla Rae
|Doug F. O'Neill
|Sunset Glow
|Wesley A. Ward
|Windy Forecast
|Simon Callaghan
|Cougar II H. (G3)
|Real Good Deal S.


text:
Our team of medical graphic designers have considerable expertise in producing all types of graphics for healthcare and where projects are aimed at patients we are experts in producing accessible information that conforms to the principles of the NHS.
Accessible patient information is a crucial part of the patient journey. It is important in achieving informed consent and is a key element in the overall patient experience enabling patients to make informed decisions about their care. We are passionate about developing good communication and understanding for patients – health literacy.
"Because health literacy includes the word "literacy", many people assume that it is only a concern for those who can't read; this is incorrect. People have difficulty in understanding health information and advice for a whole range of reasons including literacy, age, disability, language, culture and emotion" Helen Osborne, 'Health Literacy from A to Z', 2005.
Health Literacy is about the many ways that providers communicate with patients and our team of medical illustrators are experts in developing patient information and have won many awards and commendations for this work including the prestigious BMA Patient Information Award from the British Medical Association. We can also advise on all aspects of NHS branding.
We are specialists in the design and production of large or small format digitally generated posters, with an in-depth knowledge of scientific and medical subjects. Simply dropping information onto paper is likely to be inadequate in most cases. Close liaison between the client and graphic designer is necessary to clearly identify a posters task and our team of experienced designers produce posters for both national and international meetings where they have won numerous awards.
With a growing emphasis on research we offer a range of poster services from bespoke design through to the supply of simple templates and we also provide an output service for customer's who have created their own posters.
Exhibition panels, posters and banners are useful in a variety of situations; public information, scientific meetings, research presentations and promotions and our team is very experienced in developing a wide range of exhibition material for professional exhibitions such as the RCN Conference and public events. We can also supply roll-up retractable banner stands which are easy to assemble and create instant impact.
Our designers work directly with customers to ensure that graphics projects are attractive, fit-for-purpose, cost effective and functional in their design. We do not use account handlers and by working closely together you can really influence the success of your project.
Whether it's a pamphlet about your opening times or a glossy annual report, we undertake design tasks of any size incorporating beautiful photography and illustration. We will work from your brief and develop ideas and roughs through to the final concept and we'll arrange to print it too.
Corporate design products include brochures, publicity material, custom stationery, newsletters and websites, or we can create a whole new branding for your service.
A website can really help an organisation to achieve its objectives. The first key stage when developing a web site is to consider the needs of your users. Adopting a user-centred approach will provide site visitors with the information they want, when they need it, in a way they easily understand. Supporting your users' goals is crucial if your site is going to successfully promote a positive image about your service.
Whether you are looking for a completely new website, or illustrations and photographs to help improve your current site, we can help with all your web design needs and you can be assured that we speak your language and pride ourselves on providing pragmatic, functional design that doesn't cost the earth that is accessible to all and conforms to DDA standards.
Our expert medical illustrators have won numerous awards and can provide illustrations in various styles for different applications, from full colour highly detailed drawings to schematic diagrams – for use on the printed page or in digital format for web-sites and presentations.
Our previous illustrative work has included anatomical, clinical, pathological and surgical illustration for text books and journals through to more creative patient-friendly work for use in various patient education and training literature.
Our team is experienced in dealing directly with customers to help visualise their ideas.


text:
Boeing profits beat estimates despite Dreamliner crisis
Boeing's first-quarter profits beat analysts' forecasts despite the grounding by airlines of its 787 Dreamliner due to battery problems.
Net income for the first three months of 2013 jumped 20% to $1.1bn (£720m) despite revenues down 2.5% to $18.9bn.
Chief executive Jim McNerney said Boeing would resume deliveries of Dreamliners in early May.
There are reports that Ethiopian Airlines may on Saturday be the first carrier to resume Dreamliner flights.
The plane was grounded in January.
In a statement on Wednesday, Mr McNerney said Boeing "worked around the clock to resolve the 787 battery issue while also successfully increasing production rates on the 737 and 777 programs.
"Our first priority in the days ahead is to fully restore our customers' 787 fleets to service and resume production deliveries. Our outlook for the year is positive, and our financial and delivery guidance is reaffirmed as we remain focused on the profitable ramp up in commercial airplane production rates."
Mr McNerney added that Boeing would have fitted most of the replacement batteries to the 787 fleet by the middle of May.
Boeing did not release an estimate for the cost of the Dreamliner problems, as some analysts had expected.
Batteries overheated on two of the new jets in January and led regulators to ground the aircraft.
The US Federal Aviation Administration approved Boeing's fix for the battery system last week.