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Faculty Office:
Viikinkaari 5 E (P.O. Box 56)
00014 University of Helsinki
Phone +358-(0)294 1911 (University)
New associate professor Vincenzo Cerullo: Personalized drugs are on the way
Vincenzo Cerullo started in the beginning of September as a tenure track associate professor in the Faculty of Pharmacy. He focuses on personalized drugs – drugs that work only for a specific tumor in a specific patient.
Vincenzo Cerullo is the newest professor in the Faculty of Pharmacy. He begun as a pharmacist and wrote his thesis on biotechnology. Now he's focusing on personalized drugs – drugs that work only for a specific tumor of the patient they are made for. All this can happen with the help of viruses.
– Evolution made viruses a good tool. They talk to the immune system, so we try to make viruses say what we want. We can for example make viruses target certain cell types in tumors, Vincenzo Cerullo explains.
It all started during his years in the U.S.A. Cerullo worked in the Department of Human and Molecular Genetics in the Baylor College of Medicine. The researchers tried to find out how to to replace defected genes with the help of adenoviruses.
In the system called the helper-dependent adenoviral vectors the virus genome is first depleted of all viral genes. Then they are replaced with the functioning version of the gene that needs repairing. The virus enters the cell and releases the gene inside.
If things go well, the infected cells can express that gene for all their life. One of the great advantages of this system is that the the gene does not integrate in the cell's genome. That's why there is no risk for insertional mutagenesis where the original DNA could change because of the inserted and integrated repair gene.
Vincenzo Cerullo is very exited about his experience in the U.S.A. His eyes are smiling when he tells that there are baboons treated with this virus eight years ago still expressing high levels of the gene that the researchers put in their liver with the helper-dependent adenovirus. This approach could solve various monogenic diseases with a single dose.
The immune system kicks in
The only problem with the helper-dependent adenoviral vectors is that the amounts of the adenoviruses injected to the blood stream need to be very high to achieve a therapeutic dose. That kind of doses invariably turn the immune system on, which then can cause big problems.
– We in our research kind of got stuck with the immune system and felt disappointed. Then I started to think how we could take advantage of the immune system itself. I came to Finland and came across the oncolytic viruses that can selectively kill cancer cells. Then is was finally clear to me that we could use them to turn on the immune system. The virus is, after all, eliminated quite fast by the immune system, but if we we could find a way to disguise the virus as a tumor, we could divert the immune system towards it.
Vincenzo Cerullo explains that tumors are difficult targets.
– They are made of our cells, they are us. Still, I think we now have a good idea how to discriminate tumor cells from our other cells and be able to get at the ones we want.
Teaching is fun!
Vincenzo Cerullo freely admits that he loves teaching.
– I really couldn't think of this job without teaching. I look forward to it as I have had a lot of fun in the past. I have done all the pedagogic courses the University of Helsinki has to offer. They have given me great tools and a different approach as a teacher.
Vincenzo Cerullo moved to the Division of Biopharmaceutics and Pharmacokinetics from Biomedicum.
– The migration was very easy, because the head of the division, Marjo Yliperttula, has supported me tremendously since my arrival. And I'm also grateful to the people that have joined my research group. To join the group of a young researcher you need to be courageous and to love challenges. And probably these two qualities will one day make you a great scientist, Cerullo says.
Also student mobility is important to Cerullo. Already as postdoctoral researcher in Biomedicum Vincenzo Cerullo organized the postdoctoral training of his two younger colleagues in two of the most prestigious research groups in Texas Medical Center in Houston, U.S.A..
– I, too, am so grateful to all the researchers that I have met in Italy, U.S.A, Finland and around the world for the contribution to my own education, Vincenzo Cerullo thanks warmly.
More information in English
As a non-Finnish speaker Vincenzo Cerullo sometimes feels excluded of the university's information stream. English is the common language in many research groups but the bulk of the general information still comes in Finnish.
– If the university aims to be among the best universities in the world, we should open it more. That includes language. It really doesn't matter if English is something else that perfect. There are only a few native English speakers here, and they probably already have got used to other people mishandling their language, Vincenzo Cerullo grins.
text and photo: Elina Raukko
Vincenzo Cerullo in the University of Helsinki research database Tuhat
Faculty of Pharmacy, Division of Biopharmaceutics and Pharmacokinetics
The American Society of Gene and Cell Therapy: New investigator of the month
Research databases


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Soul Source Site Information
New Event Guide Reminder Feature 26/07/17Can now get personal event reminders sent to you via the event guide ....click to read more
"At the top of the stairs"
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Cafe Vogue is a new wine bar in the centre of Wigan (next to Little fifteen), serving a great range of continental lagers, plus wines, cocktails and some more usual stuff too. Very smart with a "dance anywhere" policy - the whole floor space is useable and large enough for a few dozen dancers. Owned and operated by soul enthusiasts, it already plays host to late-night weekend parties which feature a large percentage of soul music.
Now every Sunday from 3pm to 9pm, admission is free, and expect quality tunes from Wigan, Mecca ,Torch with a smattering of crossover/modern soul. DJ Deano presiding.
More info: 07552 766355.
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A POPULAR Southampton pub has been put up for sale.
The Ship Inn, in Victoria Road, Woolston, above, is on the market with a guide price of £350,000.
The pub is located opposite the new Crest Nicholson Centenary Quay development, which will provide new homes, retail space, restaurants and a supermarket.
Owners Punch Taverns have appointed international real estate advisor Savills to find a buyer for the two-storey building, which also has the potential to be redeveloped into a residential property.


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TAG has a target opening date
Troy Guard was cooking again last night, and it felt good. The former Nine75/Zengo chef had joined Jamey Fader as a guest chef for a special dinner at Lola featuring dishes inspired by the flavors of Cabo and the Yucatan. It wasn't much of a stretch for Guard, who was raised in Hawaii, and it made him eager for a place of his own. r"I'm anxious to get back into the kitchen," he admitted.
And after an almost two-year hiatus, it won't be long now. Guard now has an opening date for TAG, the restaurant he's opening at 1441 Larimer, "May 18," he offered, "but that's not 100 percent concrete."
TAG certainly won't open any earlier, because Guard is one of the five Denver chefs who'll be cooking at the James Beard House on May 13.
TAG's had its liquor-license hearing this week, and has already found a label for its fare: "continental social food." Guard has also found plenty of support from his neighbors on Larimer Square: chef/owners Jennifer Jasinski and Frank Bonanno of Rioja and Osteria Marco, respectively.
"It's really something special," he says of the block. "They've been really welcoming."
Now we can get ready to welcome TAG come mid-May.
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Is 'House Hunters' Really a Fake TV Show?
HGTV has a lot of explaining to do.
New evidence suggests the network's hit TV program House Hunters is fake. The show revolves around new young couples in search of their affordable dream homes. The A.V. Club, who first reported the news, says the rumors have been around for some time.
EW reports:
A woman named Bobi Jensen shared her experience about being featured on House Hunters with the blog. She explained that the producers changed her and her husband's story about why they were moving, and also shed some light on how those three houses that potential buyers choose from are selected. Jensen explained that prior to being selected, they had already chosen their new house. The other two "options" were just their friends' houses that weren't even for sale.
Producers from the show are denying the claim and say their show is absolutely not a fraud or scam.
The publicist for House Hunters told EW in a statement:
We've learned that the pursuit of the perfect home involves big decisions that usually take place over a prolonged period of time — more time than we can capture in 30 minutes of television. However, with a series like House Hunters, HGTV viewers enjoy the vicarious and entertaining experience of choosing a home — from establishing a budget, to touring properties and weighing the pros and cons of each one. We're making a television show, so we manage certain production and time constraints, while honoring the home buying process. To maximize production time, we seek out families who are pretty far along in the process. Often everything moves much more quickly than we can anticipate, so we go back and revisit some of the homes that the family has already seen and we capture their authentic reactions. Because the stakes in real estate are so high, these homeowners always find themselves RIGHT back in the moment, experiencing the same emotions and reactions to these properties. Showcasing three homes makes it easier for our audience to "play along" and guess which one the family will select. It's part of the joy of the House Hunters viewing experience. Through the lens of television, we can offer a uniquely satisfying and fun viewing experience that fulfills a universal need to occasionally step into someone else's shoes.


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Gerald Walker x Bryant Stewart – Focused [Music]
Following their previous collaborative single "Blame It On The Game" Bryant Stewart and Gerald Walker have joined forces for a second time for the new single Focused. The Chicago / St Louis combination is proving highly popular, and I should expect to receive more music from the duo throughout the course of 2010. Rumours of a collaborative project have circulated the Internet, and an official press release should be sent in the forthcoming months. You can listen to Gerald Walker x Bryant Stewart – Focused on the player below.
[wpaudio url="http://www.hip-hopkings.com/wp-content/uploads/2010/02/Focused-Produced-by-The-Commission.mp3″ text="Gerald Walker x Bryant Stewart – Focused" dl="0″]
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10048668, Bolt
Please help our community — upload your photos of 10048668.
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This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
In the last seven years, optoelectronic tweezers using optically-induced dielectrophoretic (ODEP) force have been explored experimentally with much success in manipulating micro/nano objects. However, not much has been done in terms of in-depth understanding of the ODEP-based manipulation process or optimizing the input physical parameters to maximize ODEP force. We present our work on analyzing two significant influencing factors in generating ODEP force on a-Si:H based ODEP chips: (1) the waveforms of the AC electric potential across the fluidic medium in an ODEP chip based microfluidic platform; and (2) optical spectrum of the light image projected onto the ODEP chip. Theoretical and simulation results indicate that when square waves are used as the AC electric potential instead of sine waves, ODEP force can double. Moreover, numerical results show that ODEP force increases with increasing optical frequency of the projected light on an ODEP chip following the
We present in this paper a theoretical formulation on the dependence of the magnitude of ODEP force on: (1) the optical spectrum of the projected image on a photoconductive material; and (2) the applied AC bias waveform across the fluidic medium in an ODEP chip. We note that G. B. Lee's (a co-author of this paper) group has already demonstrated the increase of ODEP force due to different image colors projected onto the surface of an ODEP chip in [
A three-dimensional view of the geometry of the ODEP chip used in our simulation and experiments is shown in
The magnitude and directions of the generated ODEP force depend on several physical factors, which are briefly described as follows. The time-averaged DEP force exerted on a sphere in a fluidic medium is given as [
In the above equation,
The absorption coefficient of the a-Si:H is proportional to illumination intensity [
Photoconductivity of the a-Si:H as a function of different light colors.
|Wavelength (nm)
|Averaged Absorption Coefficient (m−1)
|Photoconductivity (S/m)
|Max: 700
|1 × 106
|1.1 × 10−5
|Mean: 660
|1.7 × 106
|1.8 × 10−5
|Min: 620
|3.1 × 106
|3.1 × 10−5
|Mean: 605
|4.3 × 106
|4.2 × 10−5
|Mean: 580
|5.7 × 106
|5.3 × 10−5
|Max: 570
|6.8 × 106
|6.3 × 10−5
|Mean: 530
|1.1 × 107
|9.6 × 10−5
|Min: 495
|1.7 × 107
|1.3 × 10−4
|Mean: 485
|1.9 × 107
|1.5 × 10−4
|Mean: 463
|2.5 × 107
|1.8 × 10−4
|Max: 450
|2.8 × 107
|2.0 × 10−4
|Mean: 415
|3.6 × 107
|2.5 × 10−4
|Min: 380 *
|4.5 × 107 *
|2.9 × 10−4
* Note: This averaged value was calculated based the absorption coefficient of a-Si:H at 380 nm from [
Absorption coefficient of a-Si:H
Using the values of the photoconductivity from
In general, as shown in
Maximum DEP force acting on a 10 μm polystyrene bead with respect to different light colors (optical wavelength). The simulation conditions are exactly the same as those given in
As reported by many research groups (e.g., see [
As discussed in [
Then, Equations (4) to (1) and solving the velocity
Equation (5) also shows that the
Now, the RMS value of any periodical signal can be obtained by the following Equation [
Hence, theoretically, a
Simulated potential voltage distribution for the "light trap" used in our experiments as the virtual electrode.
We note here that there are several AC related electrokinetic phenomena in an ODEP device, including the DEP force, light-induced electrothermal effect (LIET) [
Electrokinetics analysis for a 10 μm polystyrene bead, which shows that the DEP force dominates the micro-manipulation process when the applied frequency is higher than ~15 kHz. Here, we have assume deionized water is the liquid medium at room temperature, with k = 0.6 J·m−1·s−1·K−1, ρm = 1 g·cm−3, α = −0.4% K−1, β = 2% K−1, and ∂ρm/∂T/ρm = 10−4 K−1.
We have performed several experiments using the ring-shape light pattern as a virtual electrode (as illustrated in
Experimental process of the ODEP manipulation of a 10 μm polystyrene bead using the square wave (
In this paper, two important factors that affect the magnitude of the DEP force generated in an ODEP chip are discussed and analyzed both theoretically and experimentally. The effects of AC potential waveforms across the liquid medium of an ODEP chip were analytically determined. Moreover, the effects of the optical spectrum of the projected image on the a-Si:H layer on an ODEP chip were obtained numerically utilizing the finite element software Comsol. Analytical results indicate that an AC square waveform potential applied across an ODEP chip can produce twice the magnitude of DEP force in an ODEP chip as compared to a sine waveform. Numerical results indicate that the maximum DEP force generated on an ODEP chip decreases with increasing optical wavelength of the projected image on the a-Si:H layer. This decreasing trend closely follows the
This work is supported by a self-sponsored project of the State Key Laboratory of Robotics (No. 2009Z02). This project is also partially supported by the CAS/SAFEA International Partnership Program for Creative Research Teams. Wen J. Li would like to thank the City University of Hong Kong for providing partial support (Funding No.: 9610216) to this project. The authors would like to thank all the members of the Micro/Nano Automation Group of the State Key Laboratory of Robotics, SIA, CAS, for their valuable discussions and support.


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15 result(s) displayed (151 - 165 of 252):
|Kate Fagan has a solid piece on Andre Iguodala and the Philly fans' love/hate relationship with him. We've seen this odd dynamic play out right here on this blog in the comments section for a couple of years now, you all know where I stand. A couple of interesting quotes from the article after the jump.
|I'm not quite ready to turn the page to game two prep yet, I'm still running that game one finish over and over in my mind. I left a few key points out of the recap, so here are some bullets to get your day started.
|Charles Barkley during halftime of tonight's game: "The Sixers won't win a game in this series." Any wonder how Charles has lost millions gambling in Vegas? After the jump we'll look at the rotations and talk about the perfect defensive game plan, the Sixers' secret weapon and the epic comeback that put our Sixers in the driver's seat of this first-round series.
|Video of Andre Iguodala's game-winner against the Orlando Magic tonight.
|I don't like to say I told you so, but Dwight Howard finished with 31 points, 16 boards and 2 blocks. The Sixers won. Play him one-on-one, limit open threes, and this team is very, very beatable, no matter what Howard does..
|Part three of the playoff matchup series features Andre Iguodala vs. Hedo Turkoglu. Game on the line, these are the guys who will have the ball in their hands. I'll break it down for you after the jump.
|I guess 7 really is their lucky number. The Sixers are now in prime position to not only finish with the #7 seed in the East, but also 7 consecutive losses. You'd think they'd have a decided advantage with both Kevin Garnett and Ray Allen missing from Boston's lineup. Maybe they did, but they certainly didn't take advantage of it in their 100-98 loss to the Celts.
|And the Sixers' impersonation of the New York Mets in September continues... Forget the fifth seed. The Sixers will need a minor miracle to hold onto the 6th seed at this point. Truth be told, I'd say there's a 90% chance they wind up #7, with a 40-42 record. Incidentally, the other 10% chance is that they'll finish #8, not #6. How can you look at yourself in the mirror after losing to the Raptors in this situation?
|When you hear something repeated time after time after time, a little part of you starts to believe it just might be true. I've resisted the temptation when announcers like Jon Barry try to pound the following point home, "Andre Iguodala is not a number one," and I think it's time to take a look at whether or not this particular piece of propaganda is true.
|I'd like everyone to think back to late April, 2008. The Sixers backed their way into the playoffs, finishing with the #7 seed and a first-round matchup with the Detroit Pistons. Mo Cheeks out-coached Flip Sanders in game 1, basically daring Detroit to become a one-man team by refusing to double Rasheed Wallace. Eventually, the Pistons realized that if they shut down Andre Iguodala, the team simply wouldn't be able to score enough to win. When the playoffs come around this season, that approach simply will not work.
Latest comment: from BrianThey definitely backed into the playoffs last year. 3-7 in their last 10 games, lost their last 4. ...
|The first half was just pure punishment doled out by the Sixers on the Kings. The second half was punishment for all Sixers fans still watching. All told, they needed a win, they got the win and they didn't have to sell their souls to get it. Not a bad night.
|Iguodala's buzzer beater video, check it out after the jump.
|Is there a moment when a player becomes a star? Is there one defining play? How about one defining quarter? If any of these arbitrary things can make a player into a star, I think we may have just witnessed a transformation.
Latest comment: from BryonJohn-ism = I know everything and you guys know nothing. Spare us all, John, spare us all....
|It's always fun to take a look at the stats when a player is on a hot streak. After the jump we'll break down Thad's play from the past five games.


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Residents in the village of Deshler may be able to obtain flood insurance in the near future, after council discussed moving forward with a resolution with FEMA. That resolution is a requirement, along with council's designation of flood zones in the village.
Spring cleanup in the village of Deshler is set for May 8th. Residents can drop-off items that day only at the municipal swimming pool parking lot.
Panning Excavating is offering a curbside pickup of brush and yard waste for Deshler residents on the dates of April 21st and 28th. No bags will be allowed in this pickup. And residents of Deshler can drop-off brush for free at the Panning Excavating location along state route 18 during the days of April 21st through 25th. This offer is being made in celebration of Earth Day.
And the Deshler American Legion has announced they will be making a donation to the fish stocking program at the village reservoirs this year.


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by Staff Writers
Paris, France (ESA) Jul 10, 2012
Over a dozen radio signals that have hindered data collection on ESA's SMOS water mission have been switched off. The effort also benefits satellites such as NASA's Aquarius mission, which measures ocean salinity at the same frequency. We all know what happens when you place a cell phone too close to a speaker: seconds before the phone rings, that obnoxious buzz interrupts your favourite song.
This is radio interference - an unwanted reception of radio signals. Not only can it interrupt the music from your stereo, it can also impede satellite measurements.
ESA's Soil Moisture and Ocean Salinity (SMOS) satellite was launched in 2009 to improve our understanding of our planet's water cycle. In order to do this, it measures the microwaves emitted by Earth in the 1400-1427 MHz range.
SMOS immediately revealed that many unlawful signals were being transmitted around the world in this frequency range, rendering some of its measurements unusable for scientific purposes.
Over the years, ESA has investigated exactly where the interference is coming from.
As national authorities have collaborated with ESA to pinpoint the origin and switch these unlawful emissions off, the interference has waned.
One of the largest areas of contamination in the northern hemisphere is over the North Pacific and Atlantic oceans, primarily from military radars.
Over recent years, authorities from Canada and Greenland have been asked to take action. Canada started to refurbish their equipment in late 2011, while Greenland switched off their transmitters in March 2011.
At least 13 sources of interference have now been switched off in the northern latitudes. This has significantly improved SMOS observations at these high latitudes, which were previously so contaminated that accurate salinity measurements were not possible above 45 degrees latitude as the satellite headed north.
However, the few remaining sources can contaminate areas 3000 km away, especially as SMOS climbs north towards North America.
The efforts to reduce interference will benefit other missions carrying similar detectors, such as NASA's Aquarius satellite, which was launched last year.
Aquarius also observes ocean salinity and, in addition, it measures sea-surface roughness to help understand how roughness affects salinity measurements.
A unique feature of SMOS is that it also measures soil moisture. SMOS and Aquarius readings are highly complementary: SMOS repeats coverage faster and at finer detail, while Aquarius has better 'pixel by pixel' accuracy.
Scientists are trying to combine both sets of measurements in the best way to improve global salinity maps.
"Combining SMOS and Aquarius new observations will allow us to map ocean surface salinity with an unprecedented spatial and temporal resolution," said Nicolas Reul from the French Research Institute for Exploration of the Sea.
"In particular, salinity fronts and the movement of water across tropical oceans and within strong currents - such as the Gulf Stream - shall be better detected and tracked than with single-sensor observations."
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text: Export-Import Bank is vital, necessary for continued growth and prosperity By Jeff Wasden on July 11, 2014 WASDEN: PRIMARY MISSION IS JOB CREATION Too often, politics hamper the ability of businesses to expand and put Americans to work. What used to be an important bipartisan reauthorization of the Export-Import Bank has now fallen firmly in the crosshairs of some members of the GOP. Charges of crony capitalism and big governmental overreach flow […]This content is only available to subscribers. Login or Subscribe Share this:EmailTwitterFacebook Default, GUEST COLUMNIST, Jeff Wasden


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TOP STORY >> Sherwood I-440 route submitted
Leader staff writer
The state Highway and Transportation Department has picked a preferred route for the controversial Sherwood segment of the North Belt Freeway, commissioner Carl Rosenbaum said Tuesday night at a reception hosted by the Jacksonville Chamber of Commerce.
If the proposal stands up to scrutiny by the Federal Highway Administration and at public hearings planned for area residents, the route will run from Hwy. 67-167 across Sherwood north of the route rejected last time but south of the northernmost proposal.
The route would run roughly like this: It will pass north of Indianhead Lake, cross Hwy. 107 south of Fears Lake, then north of Oakdale Road, crossing Kellogg Acres Road. From there it would cut across to Wayside Road, then southwest to Batesville Pike, where it will join the previously determined route through the southern edge of Camp Robinson and on to I-40 and I-430, near Crystal Hill.
If money were available, the route could be open within about five years, Rosenbaum said. There is, however, no money for the project unless the portion between Hwy 67/167 and Hwy. 107 is built as a toll road. The tolls there could pay about 90 percent of the $90 million needed for the project. It would carry an estimated 40,000 vehicles per day, he said. Two public hearings on the proposed route will be held next month, Rosenbaum said.
The meetings will be from 4 p.m. to 7 p.m. Tuesday, March 20 at the Church of the Nazarene, 9860 Brockington Road and Wednesday, March 21 at Cato Elementary School, 9906 Jacksonville Cato Road. Jacksonville chamber members learned that the $2 million relocation in front of Lowes Home Center of the northbound entrance ramp onto Hwy. 67/167 from T.P. White Road should be completed by late this year. It will include a new traffic signal at the intersection of T.P. White and Madden roads.
The department will study the notion of also adding an exit ramp in the same area. Jacksonvilles road list includes many wishessome as small as a sidewalk, others as expensive and complex as completion of the North Belt Freeway. The wish list includes the needs or dreams of various Jacksonville officials, developers and others in the community, and several of the smaller items on the list have been undertaken and completed relatively quickly in recent years.
As a result of these chamber get-togethers, the John Harden Drive-Vandenberg Boulevard in-tersection has had lanes added to minimize southbound congestion and in recent years the ramp dumping traffic from Hwy. 440 onto northbound Hwy. 67/167 has been lengthened to make the highway both less congested and safer.
Sidewalks from James Street to Dupree Park along Redmond Road have been completed and a Highway Department grant has been approved to extend the sidewalk from Dupree Park on to the Community Center on Municipal Drive, said the mayor.
Engineering has been completed and the right-of-way purchased to move the Hwy. 67/167 northbound from its current location across from Lowes Home Improvement Center further north and out of Vandenberg Boulevard congestion. Jacksonville Mayor Tommy Swaim said hed also like to see a new off-ramp built in that area, but thats not yet approved or funded and is far from certain.
Engineering has begun for the widening of Graham Road from Loop Road to Oak Street and the project is approved for the future, but not yet funded, according to Swaim. That project will cost about $5 million, with the citys share about $1 million. This is an opportunity to visit with the leadership of the Highway Department and the commissioners, said Swaim, who called the list a compilation of the wishes and needs of chamber members and local government officials.
The list includes widening of U.S. Hwy. 67/167 from I-40 to North Belt Loop to six lanes. Most of that is currently completed with the widening of the northbound lanes from Keihl to Redmond Road just beginning, with the final segment to be the southbound leg from Redmond to Keihl, according to Metroplans Richard McGee.
Until the entire route from I-40 to the North Belt and Redmond Road is completed, Hwy. 67/167 will continue to function as a four-lane highway. Also on the wish list is increasing Hwy. 67/167 to eight lanes between the North Belt Loop and Main Street and widening from four to six lanes the highway from West Main to Hwy. 5 at Cabot.
Both Metroplan and the state Highway Department have approved making both John Harden Drive and T.P. White Drivethe Hwy. 67/167 frontage roadsinto one-way roads between the James Street overpass and Vandenberg Road, but there are not currently funds available, Swaim said.
John Harden eventually will be one-way south and T.P. White will be one-way north, with a flyover turnaround at James Street allowing motorists on John Harden to get easily over to T.P. White and another flyover or cross under at Vandenberg to allow motorists on T.P. White to get over to John Harden. The new highway structures and one-way frontage roads are still well in the future, businesses and others are frequently resistant to the change to one way, said Swaim. Holding hearings early on would help alleviate their fears as well as fine-tune the project to minimize disruption.
Motorists would be expected to adapt quickly to one-way frontage roads and turnarounds as they have further south along Hwy. 67/167 between Wildwood/Trammel roads and McCain. Apart from the turnarounds to accommodate the frontage roads, local officials also want improvements to the James Street overpass and the Vandenberg Boulevard area.
The list of long-term projects includes several proposed by the Dupree family, the developers of the Legacy Center, but not currently approved by either Metroplan or the state Highway Department. The Duprees and their supporters would like the section of the North Belt Loop from Hwy. 67/167 to Hwy. 107 built next, to include a full interchange at Oneida Street.
The Highway Department has no current plans to close the Redmond Road ramps on Hwy. 67/167 in favor of a full-fledged interchange constructed between West Main Street and the North Belt Loop. Metroplan and the Highway Department say theres not sufficient room between those two interchanges for a third one, but the Duprees engineer disputes that claim. That study has been given to the Highway Department.
They also say it would facilitate a second east-west traffic corridor through the city, this one in the developing southern part.
Completion of the four-laning of state Hwy. 107 from Kellogg Road to the west gate of Little Rock Air Force Base is complete or underway in most sections, with the segment from Brockington Road to Bearpaw Lane being designed and work from Gravel Ridge to General Samuels yet to be completed, according to Richard McGee of Metroplan.


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October 2000 News
|Greeting from the Chair
Welcome to Literature colleagues, students, and staff as we begin the academic year 2000-2001. I hope you had a pleasant and productive summer.
Let me begin by thanking you for your concentrated efforts over the past two years as we have faced the challenges and opportunities in the Humanities, generally, and in comparative literature and cultural studies, particularly. In this, my last year as chair, we will continue these efforts, especially by focusing on the ways in which we wish to grow as a department in the decade ahead. This will involve in-depth discussions about new faculty positions, new areas of study, the refinement of our graduate program, and our relation and collaboration with programs, colleges, and departments across the campus.
We have two new faculty members this year: Jin-kyung Lee, Assistant Professor of Comparative Asian Literature and Culture, and Nicole King, Associate Professor of 20th c. African American Literature and Culture. Please join me in welcoming them to our Department.
Faculty recruitment will be a continuing effort this year. We will be recruiting again for two positions that we did not fill successfully last year: in Modern and Contemporary Chinese Literature and Culture, and in African American Dramatic Literature (this latter will be a joint appointment with the Department of Theatre and Dance). In addition, I am happy to report that recruitment is now underway for two new ladder-rank faculty positions: in Literatures of the Americas, and in Fiction Writing and Literature. Candidates for all four searches will be visiting the campus in January and February. I thank you in advance for your interested participation in these searches.
My best wishes for a successful academic year.
Lisa Lowe
Nicole King joins our department as Associate Professor of 20th c. African American Literature and Culture. A specialist in Caribbean and Black U.S. literature, Professor King received her B.A. from Princeton University in 1986 and her Ph.D. from the University of Pennsylvania in 1994; she has taught for the past six years in the English Department at the University of Maryland. Nicole King is the author of Circles of Influence: C. L. R. James and the Idea of Creolization (forthcoming, University of Mississippi Press). Her new research addresses African American literary and cultural production in the latter half of the twentieth century.
Jin-kyung Lee is a newly appointed Assistant Professor of Comparative Asian Literature and Culture, with an emphasis in modern Korean studies. Professor Lee received her B. A. in English Literature from Cornell University in 1986 and her M.A. in Comparative Literature from the University of Wisconsin-Madison in 1990. She received her Ph.D. in Comparative Literature from UCLA in 2000. Her doctoral dissertation is titled "Autonomous Aesthetics and Autonomous Subjectivity: Construction of Modern Literature as a Site of Social Reforms and Modern Nation-Building in Colonial Korea, 1915-1925."
We are pleased to announce the arrival of three new staff members over the past several months:
Gretchen Hills joined the Undergraduate Office staff last Winter Quarter. She provides information to students on academic requirements and policies, coordinates audio-visual and textbook orders, prepares the quarterly course description booklet and majors newsletter, processes student petitions and forms, distributes mail, and maintains key control. She acts as primary receptionist and provides general support to the faculty and Undergraduate Office.
Diane Lucette Wells joined the Undergraduate Office during the summer. She advises students on major/minor requirements and forms processing, schedules classes, makes room changes, collect grade reports and oversees course evaluations. She provides assistance to Nancy Hesketh, the Undergraduate Program Coordinator.
Ron J. Kennedy is providing support to both the Graduate Program and Academic Files Offices, filling in as needed on a temporary basis.
And please join us in conveying our appreciation and belated best wishes to former staff members Teresa Cain, now in Student Affairs at Revelle College; Tiffany Larsen, once again living and working in Paris; and Susan Snee, who has retired following 14 years with the Department of Literature.
Steve E. Benson, Lecturer
Thomas J. Cardoza, Lecturer
Andrea D. Fishman, Lecturer
Jeffrey Geoghegan, Assistant Director,
Revelle Humanities Writing Program
Raiford A. Guins, Lecturer
Karen Hollis, Lecturer
Naomi H. Iizuka, Lecturer
Patrick J. Ledden, Provost, Muir College
Jeyseon Lee, Lecturer
Sandra A. Logan, Lecturer
Douglas A. McCannel, Lecturer
Janet M. Roberts, Lecturer
Gail Scott, Lecturer
Jill Steiner, Lecturer
Malama Tsimenis, Lecturer
Jennifer Tuttle, Lecturer
Yong-gyu Kim, Ph.D., Instructor at Kyoungseung University and Korean Maritime University, Pusan, Korea, is a Visiting Scholar, under the sponsorship of Masao Miyoshi, through February 2001. His research project is titled "Critical Pursuits in the World System: a Critical Scrutiny on Fredric Jameson, Franco Moretti and Masao Miyoshi."
James Kyung-Jin Lee is a UC President's Postdoctoral Fellow for the 2000-2001 academic year, under the mentorship of Rosaura Sánchez. He received his Ph.D. in English from UCLA this past June (2000) after completing a dissertation entitled "Multicultural Dreams, Racial Awakenings: The Anxieties of Racial Realignment in American Literary Works of the 1980s." His current research will focus on brokered political identities among contemporary U.S. writers.
Christopher Morray-Jones, Lecturer, Religious Studies Program, UC Berkeley, is a Visiting Scholar, under the sponsorship of Arthur Droge, through August 2001. He is conducting research on Jewish mysticism and Christian origins.
Kyung Hee Suh, Associate Professor, English Department, Kwangju University, Korea, is a Visiting Scholar, under the sponsorship of Don Wayne, through August 2001. Her research concerns Jacobean city comedy.
Dorothy Wang (Ph.D., UC Berkeley, 1998) is spending a second year at UCSD as a UC President's Postdoctoral Fellow under the mentorship of Michael Davidson. She will continue to work on a book project dealing with experimentalism and minority writers, before moving on to begin a new position at Northwestern in the Fall of 2001.
Yin Xu, Associate Professor, Education College of Hubei, Wuhan, Hubei, PRC, is a Visiting Scholar, under the sponsorship of Wai-lim Yip, through March 2001. Her area of interest is postmodernism and literature.
Stephen Cope
Daphne Brooks has been awarded a
2000-2001 Instructional Improvement Program Grant in support of her proposal, "Black
Alternative: African-American Experimental Fiction and Popular Music in the Post-Civil
Rights Era." The goal of the project is to expand and redevelop the critical scope
and range of LTEN 187--Black Music/Black Texts: Communications and Cultural Expressions.
Exams and Defenses
The following graduate students successfully completed qualifying examinations, comprehensive examinations, or defenses during Spring and Summer 2000:
Spring 2000
Summer 1999
University of Frankfurt
Film Director (Berlin), will discuss and show slides from her new film project on Clara
lst Annual UCSD All-Grad Symposium, Saturday, November
18, 2000
Research Grants (Academic Senate Committee on Research)
The center, located near Chapel Hill, NC, offers private studies, a reference library,
editorial and software assistance, and support for information technology. Applications
and letters of recom-mendation must be postmarked by October 15, 2000.
For application materials, contact The Fellowship Program, National Humanities Center, P O
Box 12256, Research Triangle Park, NC 27709-2256; or http://www.nhc.rtp.nc.us
2001-2002 Conferences. HRI conference grants range from $5,000 to $15,000, but rarely exceed $10,000. Grants require at least 50% in matching funds from campus or other sources. The HRI Advisory Committee will award conference grants for 2001-2002 at its Fall 2000 meeting. Proposals must be received by October 16, 2000.
2001-2002 Seminars. HRI seminar grants range from $3,000 to $5,000 and are awarded with the expectation of an addiitonal 50% in matching funds. Proposals should address the benefits of hosting a one- or two-day event that assembles scholars from the UC system and other universities to discuss a particular research issue. The Advisory Committee will award seminar grants for 2001-2002 at its Fall 2000 meeting. Proposals must be received by October 16, 2000.
2002-2003 Resident Research Groups. HRI is currently inviting proposals for research groups to be in residence at the institute in 2002-2003. The Advisory Committee will select recipients at its Winter 2001 meeting. Proposals must be received by December 15, 2000.
Further information is located on the HRI website at http://www.hri.uci.edu/.You
may also wish to discuss proposal ideas with Lisa Lowe, UCSD representative on the
2000-2001 Advisory Committee.
Residential Grants. Each year the Getty Research Institute invites applications from senior scholars working on projects related to a specific theme. The 2001-2002 theme is "Frames of Viewing: Perception, Experience, Judgment." Categories of theme-related support include nine-month Getty Scholarships and one- to three-month Visiting Scholarships. In addition, Library Research Grants provide short-term support to scholars (all levels) whose projects will benefit from research in the library's collections.
Nonresidential Grants. Grantees are welcome to use the Getty Library but may pursue their research wherever necessary to complete their projects. Nonresidential grants include Collaborative Research Grants, Postdoctoral Fellowships, and Curatorial Research Fellowships.
For detailed information and application instructions, visit the Getty Grant Program
website: http://www.getty.edu/grant/research
or address inquiries to the Getty Grant Program, 1200 Getty Center Dr, Suite 800, Los
Angeles CA 90049-1685. The deadline for all Getty Research Grants is November 1,
Rockefeller Fellowships in Black Performing Arts offer support to scholars whose research examines the character and global influences of black arts and culture with a specific focus on performance. Research that furthers the understanding of the links between humanities, performance and arts generally within the specific area of black studies, or by placing black performance in a comparative context, will also be supported. Candidates should be at least three years beyond receipt of the Ph.D. or M.F.A. Two awards are anticipated--one to a senior and one to a junior scholar. The application deadline is November 1, 2000.
External Faculty Fellowships are designed to offer research opportunities to members of humanities departments and to other scholars interested in humanistic issues. Candidates should be at least three years beyond receipt of their Ph.D. Six to eight residential fellowships are offered to senior and junior scholars. The application deadline is November 15, 2000.
For the above categories of awards, stipends of up to $40,000 are offered to senior scholars and up to $25,000 to junior scholars, with an additional housing/moving allowance of up to $12,500.
Shared Research Group Fellowships are designed to foster research on topics in which a residential research group of senior and junior scholars has a shared interest. The Shared Research Group consists of two senior faculty fellows and two postdoctoral fellows. The two successful faculty applicants identify candidates for the postdoctoral positions (selection of the faculty fellows' own former graduate students is discouraged). One Shared Fellowship will be awarded for the 2001-2002 academic year. The application deadline is also November 15, 2000.
Additional information is available from Barbara Saxon or at http://shc.stanford.edu


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Cats can have a great time too. In a room designed just for them, cats enjoy oversized condos that face a large aquarium for their viewing enjoyment. Cats are offered frequent exercise in a secure outdoor enclosure where they can roll in the grass, hide under a bush, or climb a small tree. Because they are nocturnal by nature they receive additional exercise time at night.
All our condos include the following luxury amenities:


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Search Results
Title: Wilmington directory for the year 1853 : containing the names, occupations, places of business, and places of residence of heads of families and persons in business : to which is added the census of the city, a list of public institutions, and interesting statistics.
Author: Held, Joshua T.
Publication Info: Wilmington, Del. : Joshua T. Heald, 1853.
subject: [Wilmington (Del.)--Directories]


text: 6/24/10 6/24/10 POPSUGAR Celebrity Bar Refaeli Pictures of Bar Refaeli Allure June 24, 2010 by Celebrity 0 Shares Chat with us on Facebook Messenger. Learn what's trending across POPSUGAR. View on One Page Photo 2 of 5 Start Slideshow ADVERTISEMENT () Share This Link Copy ← Use Arrows Keys → 2 Previous Next AllureBar Refaeli


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Last March, Intuit's LoveALocalBusiness.com competition awarded a $30,000 small business grant to SailProud Apparel, a Boston-based eco-apparel company that creates clothing from recycled landfill materials like plastic bottles. The company was founded by then-college seniors Phil Tepfer and Charles Bogosian in 2007 with $25,000 in borrowed funds from family members, and became a quick success. SailProud's revenues were in the mid-six figure range for 2010.
Intuit's grant money is now helping the company to expand even more quickly. "Intuit's grant has helped us to reach out and connect with our community better, develop several new products, and really spotlight our business in the hustle and bustle that is the apparel industry," says Tepfer.
SailProud put a portion of the grant money towards sponsoring a booth at Boston's GreenFest environmental festival last August. More than 75,000 environmentalists attended the event, and it provided an ideal opportunity for SailProud to reach their target demographic through face-to-face interaction. The company even manufactured limited-edition GreenFest shirts, made from recycled plastic bottles, for the event. "We removed nearly 90,000 cubic inches of landfill space in making them," Tepfer says.
The company also invested a portion of their grant money into product development, spinning off a new product line called BeProud, which focuses on yogawear. They're now in the process of developing an apparel line for cyclists called GearProud, with consulting assistance from Duct Tape Marketing.
Finally, SailProud is using the remainder of the Intuit grant to work towards a goal that will benefit both the company and the environment: to recycle one million cubic inches of landfill space into shirts by Earth Day (April 22). "This goal isn't just focused on boosting production," says Tepfer, "but it's a way to prove to the world that environmental change on a large scale is possible — and that we can do it together."
Help Your Business Thrive
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Alternative flash content
XeniaLights News:
December 3, 2015
The 2015 season is underway and we have a great new layout for you to see and enjoy. We have made a major change this year from traditional christmas lights to pixel strings which allows much more variety in our display. Lights will be on from 6:00 to 10:00 PM each evening through January 1st. 2016.
For up to date new and information look for us under XeniaLights on facebook.
Thanks to everyone who attended our lightshow this year. It was the best year yet for donations to IHN. 100% of all donations recieved go to IHN.
Interfaith Hospitality Network of Greene County DONATIONS to date!!!
Again many thanks to each of you who supported our designated charity. For the last three years we have accepted donations for IHN. Each year we have taken the total donated, rounded up a little and added a little from XeniaLights for a final total donation:
In 2012 $485 donated at box, Total Donation was $750.00
In 2013 $641.36 at the box, Total Donations was $900.00
In 2014 $1,783.34 at the Box. Total Donation will be $2050.00
This is awesome and I appreciate all that attended and donated.
December 1, 2014
It is a new Christmas Season and Xenialights is once again bringing light to the holidays. Our display will be on each night from 6:00 PM to 11:00 Pm through January 3, 2015. This years display has two new features. The first is a 180 degree 14 ft. GECE based Pixel Tree that is 24 strands wide by 36 pixels high and is controlled by two Sandevices E-682 controllers. The tree only takes 3 to 4 hours to erect compared to the three days it takes to put up our led string based mega-tree that has 64 strands of 200 count lights sets. I think this may be the last year for the traditional Mega-Tree. I will be looking to replace it with a large pixel based tree.
The other new element added to our display this year is a video projector that projects images onto our garage door as part of the light show. This is featured in our new song for this season which is "Let It Go" from the movie Frozen.
October 24th 2014
Our Halloween display is up and running and will run through November 1st 2014. We have added video to the display this year. If you missed the edisplay you can see a couple of the songs by visiting our Youtube site at:
November 26, 2013
Hard at work setting up the display for this year. I had hoped to launch the show Thanksgiving evening but the weather has put me behind on my setup schedule. So the plan for now is to have the first showing Friday night, hopefully starting at 5:30 and running until Midnight. Normal hours for the display will be Sunday - Thursday 5:30 to 10:30. Friday, Saturday, Christmas Eve and New Years Eve - 5:30 to Midnight. The show will run from November 29th through January 3rd.
October 2, 2013
The Halloweenlights are going up in just over three weeks and here is a video of the first test of my new Monster Quartet. All sequencing (face animation for this song was done by Xenialights)
September 22, 2013
Fall is here and we are hard at working getting ready for our Halloween and Christmas Light Shows. The Halloween lights will be up for one week from Friday night October 25 to the following Friday night November 1st. We will probably run the lights from 6 PM to Midnight on Friday and Saturday nights and 6 PM to 10 PM the other nights.
We have built new singing monster faces for this year. They are the same design as last year but twice as big. I hope to add a couple of new songs also but singing faces take a long time to program.I hope to launch the Christmas Lights on Thanksgiving night this year and run through the first week of the new year. I am also adding four singing faces to our Christmas display this year. There will be Santa, one of his elves and two singing Christmas trees. I think the kids will really enjoy the new Christmas faces which I hope to complete this weekend.My biggest challenge between now and Thanksgiving will be to find enough hours to do the sequencing required for the new faces and songs I am contemplating.And because giving back is important to us we will be once again sponsoring a donation box for the Interfaith Hospitality Network.So make plans to stop by and enjoy the lights this year!!
The XeniaLights 2012 Christmas display is history and we hope you enjoyed the show! We are actively planning and making purchases for the 2013 season. We will also once again plan to have a small Halloween display the week of Halloween.
2012 Display Videos are available on Youtube under "Xenialights"
Hello and welcome to our site, XeniaLights! We hope you find our Christmas Light display and website site interesting and enjoyable. During the Christmas season and at Halloween we would love for you to drive by and enjoy our light shows. This page is for news and announcments about our display. To listen to our lights, tune to 104.1 FM. To keep up with our progress start with our "How This All Got Started" article and then vist the "Occaisional Blog" and the rest of the website to check our progress.
Giving Back 2012! - Total donations to IHN is $775.00.
Thanks to all who gave to this worthy cause.
Especially during the Christmas Season, we should look for ways to help those less fortunate than we. As such, XeniaLights is accepting monetary donations on behalf of the Interfaith Hospitality Network of Greene County. IHN is committed to providing housing, meals, and assistance to homeless families of Greene County on a temporary basis bringing hope and a safe haven for their guests while they seek employment and permanent housing. XeniaLights is proud to sponsor this for IHN. 100% of all Donations received here will go to IHN. There is a donation box at the curb close to our mailbox.
The Donation Box is also our Candy Cane stand. Candy Canes are free to children and those young at heart and require no donation.
The XeniaLights display is fully funded by the owners and no donations will go to the display. The display is our gift to the community.
Merry Christmas from XeniaLights!
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Dessert Plates in Rose and Gold (set of two)
Suite One Studio
Out of stock
A set of two supremely glamorous dessert plates made from smooth white porcelain and a variegated handmade pink glaze that sports all the charm and variety of a watercolor painting.
The edge of each organic hand-formed plate is painted with genuine gold. The gold trimmed plate is then fired in the kiln for a third firing making these plates food safe and durable enough for daily use.
Approx. 6.5"
The Suite One Studio shop is updated every Tuesday at 7 PM EST. If you missed this top seller this week please check back during next week's update.


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A unique
column of finds in New York from the eyes of someone who is a
The Olympics are in full swing. Show your colors in statement making
twiggy LONDON
UNION JACK Ballet Flat: The Union Jack is everywhere these days. It is the
ubiquitous symbol of the UK. Iconic British super model, turned designer,
Twiggy, has fashioned it into a stylish ballet flat in three different color
variations. Available at: www.hsn.com, $49.90
TOPSHOP London
Love Ankle Socks: London has opened its arms to the world and everyone is in
love with this exciting city. Show your love with these adorable socks made of
a comfortable cotton blend. Available at:
www.topshop.com, $8.00
Gina Drew
Slingback Platform: There is nothing subtle about these elegant slingbacks that
are embellished with a Union Jack design made of shimmering Swarovski crystals.
The shoes are from Gina, creators of luxury footwear for nearly sixty years.
The British company was named for Gina Lollobrigida, founder Mehmet
Kurdashs favorite actress. Available at:
www.harrods.com, £875.00
Sebago Spinnaker
Patriot : Guys can get in on the mania for
all things British with these two-tone, classic, leather boat shoes. The Union
Jack is displayed on the slip resistant, rubber sole. Available at:
www.sebago.com, $125.00
Keds Champion
Patriotic : Root for team USA in these canvas sneakers
inspired by the Stars and Stripes. Enjoy 25% off the regular price now through
August 9, 2012. Available at: www.keds.com, $45.00
TOMS Stars and
Striped Canvas Shoes : You are never too young to catch the Olympic spirit. These
distinctive shoes are sized for children and for every pair purchased, TOMS
will donate a pair of shoes to a child in need. Available at:
www.neimanmarcus.com, $29.00 to
Havaianas Brazil
Flip Flops : The games of the XXXI Olympiad will be in Rio de Janeiro in
2016. Long before the world gathers in Brazil, you can sport these
quintessential flip flops, decorated with the Brazilian flag. They were
originally designed for the 1998 World Cup. Available at:
www.havaianas.com, $24.00
Continue to DFR: Daily Fashion


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Do Eye Shields Need to Be Used with Exilis for Facial / Under Eye Wrinkles?
Do Eye Shields Need to Be Used with Exilis for Facial / Under Eye Wrinkles?
Doctor Answers 3
No Eyeshields Needed with Exilis...
No, eyeshields do not need to be worn when treating under eye wrinkles. Radio frequency is not a laser, however, the provider who is treating you should take extra care of staying on the bone of your orbital rim...
Good luck. Exilis is a great treatment.
Dr. Grant Stevens
Learn more: http://marinaplasticsurgery.com/
Eye Shields Not Required With Exilis Treatments
Eye shields are not required when treating the face or underneath the eyes when undergoing Exilis treatments. Exilis is a radio frequency technology, not a laser thus will not damage the eyes.
We have had incredible success in our office at reducing fine lines around the eyes with Exilis! Visit the link below to see some photos of our actual patients.
Learn more: http://www.feelbeautiful.com/gallery/exilis
No eye shields needed for Exilis
Because Exilis is a radio-frequency device and not a laser, eye protection is not needed.
However, care should be taken around the eyes, as radiofrequency energy generates heat in the treatment zone. We stay outside of the bony eye socket to avoid "heating up" the eye.
Our patients have been very satisfied with Exilis, as have we.
You might also like...
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


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New Music Report: Expert Picks - Week of March 20th
There has been a lot of great new music released over the last few weeks. You can find out what was released this weekend in our New Music Report, but take a look at what we've been listening to lately. Our editors Nicole and James have shared some of their Expert Picks for the week. Check it out below:
Nicole's Picks:
Future & Rihanna - "Selfish"
I can NEVER get enough Rihanna. Before Anti came out, I was counting down the days I could listen to some new tunes from Badgalriri. Now it's been over a year since Anti has been out in the world, and since then, I've enjoyed her Drake collab "Too Good," her Calvin Harris collab "This Is What You Came For." But now Rih has teamed up with Future on "Selfish," and I selfishly can't get enough (see what I did there).
"Selfish" is from Future's HNDRXX album, which is the second album he released this year. The rapper has been busy having released HNDRXX and FUTURE only days apart. And while there are plenty of great new songs to listen to off these albums, this little gem caught my attention. Listen to "Selfish" on iHeartRadio HERE.
Also, Lorde's a fan too:
February 25, 2017
Which brings me to my next pick...
Lorde - "Green Light"
It's been a few years since Lorde released any new music. And up until she released her new single "Green Light," she had been pretty secretive about it -- but having heard the new song, it's understandable why. "Green Light" is different from the Lorde we heard on her 2013 debut Pure Heroine. The new single is much more upbeat, but is still packed with the same honest lyrics that know and love Lorde for.
Lorde recently told me of her new single, "I don't think it's what anyone could have predicted or expected, and I think since I had been gone, pop music had changed a lot, and I was definitely like, 'If I came back and did the same thing, it wouldn't feel fresh at all.' I would be so bored doing that. So 'Green Light' just felt like this very strange, confident thing of, here I am, this is where I'm at right now. Like if you want to come with us, you can come with us. People have come with us, so it's good."
Well, I am SO here for this song.
Ed Sheeran - "Supermarket Flowers"
Ed Sheeran's ÷ (Divide) is, not surprisingly, an amazing album. Every song on the new record taps every emotion -- I laughed, I smiled, I danced, I cried. All the feels came out. But this song stopped me in my tracks. "Supermarket Flowers" is one of the most -- if not THE most -- emotional song on the album, and when I first heard it, I sobbed all the way through it.
Ed explained in an interview that the song was written about his grandmother (who passed away), but from the perspective of his mother (who you might expect the song to be about after hearing the lyrics "You were an angel in the shape of my mom"). He also explained that he almost didn't put it on this album, but his grandfather encouraged him to include it. And I'm so glad he did.
If you haven't heard this album yet, please do yourself a favor and listen to it. And definitely make sure to listen to this song. Just make sure you have some tissues nearby.
Follow Nicole on Twitter: @NicoleMastr0
James' Picks:
Stargate featuring P!nk & Sia - "Waterfall"
Throwing P!nk and Sia on a song together deserves utmost attention. Even though the video isn't quite as enticing as we'd like (without appearances from either chart-topper), the Stargate-produced song, which was co-written by Diplo and Jr. Blender, is a pleasant blend of two pop titans' voices. Sure, it's a bit repetitive, but it is P!nk and Sia singing together, and we're appreciative of just that.
"Waterfalls" is the result of a collaboration with the hit-making Norwegian songwriting duo. Sia linked up with them when they co-wrote Rihanna's "Diamonds" and was the one that recruited P!nk for the upcoming single.
Stargate might not be a household name, but you've surely heard their discography. Among their noteworthy hits are Beyoncé's "Irreplaceable," Rihanna's "Don't Stop The Music," Selena Gomez's "Same Old Love," Fifth Harmony's "Worth It" and Katy Perry's "Firework."
Katy Perry - "Chained To the Rhythm" (Hot Chip Remix)
In their output since 2015, Hot Chip's Alexis Taylor and Joe Goggard give Katy Perry's "Chained to the Rhythm" a slinky facelift. On the almost-six-minute recut, the pop star's politically-charged track hits house music territory, courtesy of the London band. They speed up the BPM and chop up her vocals, inevitably concocting the perfect addition to a Saturday night dance floor playlist.
Follow James on Twitter: @newyorkinstinct


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Novel Looks At The Division Of Rutland
10/10/11 12:50PM By Nina Keck
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(Host) In 1880, Rutland was Vermont's largest and most prosperous city. But a controversial political move in 1886 forever changed that.
As VPR's Nina Keck reports, a new novel delves into the events and the man behind the division of Rutland.
(Keck) Writer Linda Goodspeed grew up in Rutland, but says she knew very little about Redfield Proctor - the founder of the Vermont Marble Company.
(Goodspeed) "When I was working on this book people would ask what are you working on, and I would say something about Redfield Proctor and the responses would almost always be, oh, yes, he's the one who divided Rutland."
(Keck) Goodspeed says she became interested in Proctor while doing research for a book on Pico Mountain, which Redfield Proctor had owned at one time. She soon found herself going through Proctor's personal papers, state archives and old newspaper clippings.
(Goodspeed) "Redfield Proctor was a very extraordinary man. I was captivated by him.
(Keck) This summer, her book Redfield Proctor and the Division of Rutland was published by the History Press.
(Goodspeed) "I wrote it as a historical novel so it is a work of fiction based on the major events of Proctor's life. But many of the words that come out of Proctor's mouth are actually drawn right from his papers."
(Keck) Goodspeed says she kept to the facts, but took liberties with character development and some dialog. She says Redfield Proctor's charisma, accomplishments and ruthlessness needed no embellishing.
(Goodspeed) "In 1869 he took over a bankrupt marble mill. He was 38 years old at the time. And within a very few short years he had turned that marble mill into the largest marble operation in the world. "
(Keck) Proctor became one of the richest and most powerful men in Vermont, holding nearly every political office in the state, including Governor. Goodspeed says in the years after the Civil War, Vermont was staunchly republican. But the many ethnic marble workers in Rutland began to organize with other labor groups and they shocked many in Vermont when they elected a democrat to the statehouse.
(Goodspeed) "Proctor of course could not abide this. He also had his eye on the national election of 1888. I think he had his eye on national office. And so he really saw an opportunity to divide Rutland in 1886 and get it back into the Republican column."
(Keck) At the time, each Vermont town had one vote in the statehouse. Proctor pushed to have Rutland carved into three smaller towns. The newly proposed towns of Proctor and West Rutland contained Proctor's Marble quarries, carving facilities and most of his employees. Vermont historian Don Wickman says that allowed Proctor to exert enormous control over how the towns voted.
(Wickman) "He would control by having company stores and company housing. So they were more or less subservient to him. I think the other catch is that those people - the ethnic groups and the laborer did not have a lot of clout in the town."
(Keck) And any clout they had begun to generate in the early 1880s was new and fragile. If Proctor got his way, one town's democratic vote would be turned into two and possibly three republican votes.
(Goodspeed) "There was enormous opposition to this proposal."
(Goodspeed) "In her novel, Linda Goodspeed includes testimony from public meetings and labor groups, letters and editorials by the Rutland Herald condemning Proctor's plan.
(Goodspeed) "And he just rammed it through. He did what he had to do to get it through the house and senate. He actually hired every lawyer in the county on retainer just to keep them away form the opposition."
(Keck) For Redfield Proctor and his fellow republicans the division was a success. The party gained two seats in Montpelier and Proctor went on to become Secretary of War and a U.S. Senator. Historian Don Wickman.
(Wickman) "I think it shows that local people did not have a lot of power at that time. Things were going to be debated up at the Statehouse. You can almost see the cigar smoking back rooms there. For Rutland I think it just changed the entire character of the community at that time. It lost probably some of its flavor back in 1886.
(Keck) Author Linda Goodspeed says Rutland lost a lot more than its flavor.
(Goodspeed) "All of the marble quarries were split off from Rutland so it's tax base was diminished by about 4/5ths. We've never really recovered from this."
(Keck) Goodspeed and other historians says what's ironic is that local citizens at the time had no say or vote on the matter. Redfield Proctor clearly benefited as did his family. Both Proctor's sons and his grandson served as governor. Redfield Proctor died in 1908 at the age of 76.
For VPR News, I'm Nina Keck in Rutland.


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The body might have been tired - after all, he had only just arrived from Europe on Thursday night - but the limbs were still lean and tan and the eyes keen and as quizzical as ever while John van 't Schip watched his players at Epping Stadium ahead of Sunday's clash with A-League champions Central Coast Mariners.
It was at once familiar and similarly all different as the tall Dutchman, dressed once again in the red, white and grey training gear of Melbourne's ''other'' A-League club, took charge of the session.
Van 't Schip, who was Heart's founding coach, the man who did such a lot to create the club and took it to a finals appearance in just its second season, is back in charge.
The circumstances, as he admitted, are far from ideal: his main involvement with Heart this year was supposed to be as a part-time technical director and mentor to the club's inexperienced second-year coaches John Aloisi and Hayden Foxe.
He found himself at Epping, in Melbourne's northern suburbs on Friday, having answered an SOS from the club's hierarchy after its patience ran out following Heart's 12-game winless start to the season.
Instead of guiding Aloisi and Foxe for the latter part of the campaign, he is replacing them after Aloisi was axed last Sunday and Foxe walked in support of his colleague and friend. ''It's never nice to come in a situation like this,'' van 't Schip said. ''I was only here just over a week ago, was watching games and being close to John Aloisi and Hayden, but we all know how football works.
''When the club asked me to help, I was back in Europe. I had a talk with my wife and decided to do it and help the club because it's a club I am very close to, I helped build it up a few years ago … for me, it was not difficult to say OK, I will come and help out for the rest of the season.''
Van 't Schip says he is not planning on a total revolution with change for change's sake. But he does want to alter the players' mindset, remove the fear that has haunted their performances, and get them playing with joy and enthusiasm.
He will not play youngsters for the sake of it, but he is likely to give fringe players and young players a chance.
''I am not just going to come here to make changes, I am going to have a good look at players who are willing to play, who have no fear. That might not always be the better player, for a lot of people, but it's about the team now, that's important.
''And I am also looking at some younger players, if I can see some knocking on the door then for sure they will get an opportunity to step in. At the moment is a bit difficult, but I will always have an eye for younger players.
''I believe in this team, otherwise I wouldn't have taken the job. They are at the bottom but that doesn't say that that's the quality of the team. There is a lot of quality here. For us, it's important now to get results and win games, but most importantly to start playing more free football.
''It's a mindset that has to change - to enjoy being on the pitch and expressing yourself as an individual and as a team. I think that's something maybe the last few months, because of the results, because of the pressure that got into the players, they didn't perform as well as they can.''
Van 't Schip so often exudes an air of coolness but despite his tiredness and the task that confronts him, he is excited at the challenge of lifting the club off the bottom of the table.
''Of course I am excited,'' he said. ''Being on the pitch today and coming out, I am a little bit exhausted but it gives energy. I feel we can still do some good things here, which is why I accepted the offer to come.''
He had been working with the Cruyff Institute, a soccer ''consultancy'' business set up by the great Dutch player Johan Cruyff, a man who was 50-year-old van 't Schip's mentor when he was a young player alongside the then-veteran legend at Ajax Amsterdam.
''I have a deal with them and one of the deals is that I am a coach,'' he said. ''When I am not coaching I work for them - I have a contract with them - but my main job is coaching the team I am with and that is now Heart.''


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Antique Silver Christmas Snowflake Charms Set F
Set of six silvertone metal flat back reversible winter Christmas snowflake charms. Colour shiny antique effect silver with black.
Sizes approx 20 mm inc loop x 15 mm, no jump rings. Material metal. You will receive six of the silver Winter Christmas snowflake flat back reversible pendant charms embellishments shown. Reverse is the same design as the front. Please note the charms are a brighter silver than appears in the photograph. A lovely design ideal for card making, scrapbooking, paper crafting, jewellery design projects etc. Add to charm bracelets, wine glass ring charms, handbag key ring fobs etc.
Price £2.35


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A post has been circulating around the web, "Helping Little Hearts Overcome Sin" about how to raise children.I want to say that it is obvious we have a seriously devoted parent here. She wants to raise her kids well. She clearly loves her children. It's a scary world out there, and the fear it may cause can be overwhelming. Lisa and I have raised three children who are now adults. Sometimes I think I would never ever want to do that again. Especially through their teen years. Other times I … [Read more...]
training up a child in the way she should go
August 29, 2013 by 28 Comments


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Sasha summarises Professor James Coyne's recent no-holds-barred talk on the PACE trial and points you to the slides, video, audio and transcript.
Discuss the article on the Forums.
Update on Alex3619: in hospital but doing well
Discussion in 'General ME/CFS News' started by WillowJ, Feb 27, 2013.
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Page 4 of 15


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Replug Audio Jack Saves Your Devices
You could have imagined this scenario before — You plug in your headphones with a short length wire to the audio jack of your music device. Halfway into your playlist, a human or animal entity decides to come between you and your treasured laptop or hifi system, either treating it as a 100-metre race ending tape or a high-jump pole. What's next? Murphy's law has already predicted that you will need to replace your audio jack or worse, the entire system. The breakaway audio jack designed by Replug could be the answer to your worst fears.
The Replug breakaway jack is designed much like a lizard's tail that it breaks off as an act of sacrifice to protect the more expensive device at the end of the cable. After the accidental break, it can be reconnected back to normal as the points are ingeniously held together by magnetism.
From the image above, it can be seen that the breakaway will work fine when the angle of the pulling force is between 90 to 180 degrees, which bends the cable. I reckon that if you tug the cable in the same direction of the jack of a lighter device, it will be dragged along as well (Try it with a magnet and you'll understand). Therefore I think would make more sense to use this to protect the heavyweights such as laptops and hifi systems rather than an iPod shuffle for example.


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About Forefront
About Forefront
Forefront is a place where expertise and partnership come together with a passion to save lives.
Mission: Forefront advances innovative approaches to suicide prevention through policy change, professional training, campus- and school-based interventions, media outreach, and support for persons affected by suicide.
Goal: To reduce the suicide rate in Washington State by twenty percent by 2020. Once successful, Forefront will broaden its outreach to other states where the rates of suicide in the U.S. are the highest.
Values: Everybody has a role to play in suicide prevention. Through education, program evaluation and system-level changes, we can increase timely and appropriate responses that can prevent many suicides.
At Forefront, we know most suicides are preventable and that the time to act is now.