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Business Coaches In North Carolina
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Terry Poling BA, MA, Plus 2nd Master's Degree in Counseling Psychology; Counseling & Coaching Certificate, and Accredited by the Institute for Independent Business.
Executive Coach, Leadership Coach, Business CoachInterviewed by Noomii
I work with leaders and high potential persons, such as CEOs, Department Heads, and Business Owners, interested in taking their leadership/careers to "the next level" of performance and fulfillment. See Full Profile →
Christine Brunet CPC
Career Coach, Business Coach, Performance CoachThose who are frustrated with their career, whether they are looking for a new job or just struggling where they are-I can help you find that fresh perspective within yourself. See Full Profile →
Akilah Ensley BA, MBA
Life Coach, Business Coach, Leadership CoachTo coach business professionals, entrepreneurs and you in your professional development and personal growth and overall enlightened living. Enabling the best and most productive change for you. See Full Profile →
Get a Coach Recommendation!
Yol Swan
Life Coach, Spirituality Coach, Business CoachI am passionate about helping spirit-led women, Indigo adults and conscious entrepreneurs to create an authentic, abundant and empowering life and business in alignment with their soul! See Full Profile →
Dr Kris Williams-Falcon Phd BA, MS, PhD, Certified Life Coach
Money and Finance Coach, Business Coach, Family CoachOur counseling and life coaching styles brings training, experience, care, skills and absolute confidentiality for all our clientele. You will be provided the opportunity to bring any concerns that you have in your life about marriage, relationships, pers See Full Profile →
Donna Strater CHC
Business Coach, Entrepreneurship Coach, Health and Fitness CoachI coach female entrepreneurs who are passionate, teachable and truly want to be successful both short and long term. I help my clients learn how to work to live, not live to work. See Full Profile →
James Murphy NLP, Hypnosis, Time Line Therapy
Executive Coach, Business Coach, Entrepreneurship CoachMen, age 25-55 who are experiencing emotional challenges in job performance, confidence, purpose, focus or business and personal relationships. Re-engage your personal power, purpose and passion. See Full Profile →
Regina Mize Licensed Profiting From Your Passions Coach
Entrepreneurship Coach, Business Coach, Life CoachI help motivated, heart-centered women gain clarity around their purpose and maximize their unique genius to build a thriving and profitable lifestyle business doing work they love. See Full Profile →
Bill Johnson
Business CoachI really enjoy working with small companies that need direction and focus to exceed customer expectations while delivering products and services that meet the needs their customers. See Full Profile →
Yolanda Dragon BA Communications/ Psychology [minor]
Life Coach, Business Coach, Relationship CoachI coach business professionals through use of guided practices to disrupt routine patterns of behaving that has resulted in stagnant careers, unfulfilled relationship, and lost visions. See Full Profile →
Michelle Fleckner BA, Bachelor of Divinity
Entrepreneurship Coach, Business Coach, Family CoachMy ideal client is looking for effective strategies and tools on how to consistently achieve their goals, effectively resolve obstacles, create meaningful relationships and develop a deep inner trust. See Full Profile →
Crystalyn Roberts
Life Coach, Business CoachSee Full Profile →
DR NATALIE MONTAGUE Six Sigma Yellow Belt, SCRUM Foundations Certified
Life Coach, Spirituality Coach, Business CoachWe are here to support your movement forward, to provide strength when courage wanes, to inspire faith when doubt arises, and to keep you accountable when old patterns surface. See Full Profile →
Can't find a neaby coach? We have a solution to that!


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Would you like to save as your currency permanently or for this visit only?
Me and my family just had to stay over the night. We should drive further north the next day. The hotel was laying on a beautiful place close to a big lake.
Beautiful outdoor surroundings. Nice buildings and very friendly staff. Good value for the price we paid for the room. Dinner cannot be recommended, but breakfast was fine.
Friendly staff members. They were Dutch family. Very friendly people. Yes, definitely recommend if you want to learn about swedish wildlife.
Very quiet, good countryside upper class style, very pleasant service people no

subset: commoncrawl


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@thecolumbian Tweetup
The Columbian
Thursday, March 1, 2012 from 6:30 PM to 8:30 PM (PST)
Event Details
We at @thecolumbian are happy to announce our very first tweet-up. We've gotten to know each other online over the past year; join us so we can get get acquainted offline, too!
The fine folks at Pizza Schmizza in Salmon Creek have agreed to host us for the first event. As a bonus, they're offering 25% discounts on all food and soda purchases for all tweetup attendees. Wi-Fi will be available for all those hoping to live-tweet the festivities.
Web Editor Libby Clark and Social Media Coordinator Matt Wastradowski will be on hand, along with some of your favorite Columbian reporters. Please introduce yourself!
Have questions? E-mail firstname.lastname@example.com or tweet @thecolumbian. Hope to see you there!
When & Where
Pizza Schmizza
910 NE Tenney Road
Suite B119
Thursday, March 1, 2012 from 6:30 PM to 8:30 PM (PST)
Add to my calendar
The Columbian
Southwest Washington's leading source of news and information.


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Subject: [htdig] bad words list & external parser
From: Mentos Hoffmann (email@example.com)
Date: Tue Apr 04 2000 - 08:40:49 PDT
It seems as if the external parser functionality does not make any use
of the bad words list. i.e. use the external parser and the bad words
list is ignored. Is this true and intended?
I can implement the bad words filter in my external parser, but using
the feature in the digger (as it's allready there) seems to be faster
and sensible.
Thanks for any comment on this,
-- Mentos Hoffmann, Roonstr.17, D-76137 Karlsruhe, Germany email: email@example.com
------------------------------------ To unsubscribe from the htdig mailing list, send a message to email@example.com You will receive a message to confirm this.
This archive was generated by hypermail 2b28 : Tue Apr 04 2000 - 07:39:39 PDT


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Labrouste (1801–75) pioneered the use of glass and iron to create soaring, light-filled, cathedral-like interiors, like the ones found in his two great libraries, the Bibliothèque Sainte-Geneviève and the Bibliothèque Nationale, both in Paris. This show, which includes some 200 objects—drawings, watercolors, photographs, films and architectural models—is the first ever U.S. survey devoted to the 19th-century French architect.
|Event phone:
|Event website:
To improve this listing email: firstname.lastname@example.com


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USA TODAY's Mike Foss previewed the World Cup, which kicks off Friday, in a live chat Thursday. Follow the conversation by clicking on the Cover It Live container below:
Reid Cherner has been with USA TODAY since 1982 and written Game On! since March 2008.
He has covered everything from high schools to horse racing to the college and the pros. The only thing he likes more than his own voice is the sound of readers telling him when he's right and wrong.
Michael Hiestand has covered sports media and marketing for USA TODAY, tackling the sports biz ranging from what's behind mega-events such as the Olympics and Super Bowl to the sometimes-hidden numbers behind the sports world's bottom line.


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Fun day in the minors for Cubs fans. Homers by Javier Baez and Kris Bryant, C.J Edwards racking up K's in his debut, Armando Rivero heating up his right arm, and even Dillon Maples has gone 10 straight innings without a walk. Rubi Silva extended his hit streak to 14 games and Zeke DeVoss upped his on-base streak to 20 games.
C.J. Edwards fanned the first seven hitters he faced in his Cubs organizational debut as the 21-year-old right-hander got the start Sunday for Daytona against Palm Beach. Acquired along with Mike Olt and Justin Grimm for Matt Garza, Edwards was also making his High-A debut and he didn't disappoint. He tossed five shutout innings allowing an infield single and finished with a line of 5IP, 1H, 0R, 1BB, 8K. Edwards said in an interview before the game he was excited for the opportunity and liked to go after hitters and get ahead in the count. That's exactly what he did throwing first-pitch strikes to 11/17 he faced. "New team, same C.J." he told Daytona play-by-play announcer Cody Dunlap after the game. Edwards said he doesn't try to strike hitters out but goes right at them, relying on his defense. He said he put his faith and trust in catcher Chadd Krist in his first start for Daytona, and threw what he called. More on Edwards' start in Daytona game recap
AAA—Oklahoma 4, Iowa 3
A two-run homer in the sixth off the bat of George Springer gave Oklahoma City (59-50) the win over Iowa (51-58)
At the Plate: Ty Wright (.261/.318/.384) had three doubles to lead the Iowa offense driving in a run and scoring one. Luis Flores (.189/.284/.318) and Edgar Gonzalez (. 293/.326/.512) were 2-4 while Jae-Hoon Ha (.214/.261/.313) doubled and scored.
On the Mound: Nicholas Struck (5-8 6.29 ERA) took the loss with a line of 5.1IP, 5H, 4R 3ER, 2B, 3K 2HR. Marcus Hatley (2-1 3.96) got the final two outs in the sixth and Chang-Yong Lim made his AAA debut with two strikeouts in two innings with two hits.
AA—Birmingham 8, Tennessee 5
Javier Baez blasted a pair of two-run homers but it wasn't enough as Tennessee (21-14, 54-49) fell to Birmingham (22-14, 65-40)
At the Plate: Javier Baez (.232/.284/.634) hit a two-run homer in the first and added a two-run bomb in the ninth but the Smokies didn't score in the other seven innings despite 12 hits and three walks. Baez has 10 homers in 20 games since his promotion to AA and has 27 HR and 76 RBI on the season. Chad Noble (.250/.312/.310) ripped a RBI double in the ninth and scored on the Baez homer. Matt Szczur (.280/.349/.368) and John Andreoli (.302/.370/.469) had two hits each while Rubi Silva (.287/.307/.499) extended his hitting streak to 14 games going 2-4.
Video of Baez's 26th homer of the season
On the Mound: Eric Jokisch (8-10 3.84 ERA/1.38 ERA) experienced his second straight tough outing giving up nine hits and three walks in five innings. Jokisch was charged with six runs, five earned, and threw 95 pitches with four strikeouts. P.J. Francescon (1-0 4.11/1.33) allowed a run in two innings on four hits and Kevin Rhoderick (1-4 5.36/1.86) worked a scoreless eighth despite two walks. Marcos Mateo (1-0 1.04/1.50 8.2 IP) surrendered a run in the ninth on two hits and walk.
Smokies Notes: Arismendy Alcantara (.268/.341/.453) got a day off from the field but was in the lineup as the DH and went 0-5. Alcantara is hitting .195 in his last 10 games and .220 in July.
High A—Daytona 2, Palm Beach 1
J.C Edwards fanned eight in his Cubs debut and a throwing error in the seventh gave Daytona (55-43) the win over Palm Beach (47-54)
At the Plate: A throwing error on Zeke Devoss' well placed bunt down the third base line scored Taiwan Easterling and Brad Zapenas for the Cubs only runs. Dustin Geiger is heating up as the first baseman went 2-4 and is hitting .333 in his last 10 games. Benjamin Carhart, Dustin Easterling and Zapenas all finished with two hits. The Cubs streak of 21 straight games with an extra-base hit was snapped as all nine of their hits were singles. DeVoss should have been credited with hit on his bunt but walked in the ninth and has reached base in 20 straight games.
On the Mound: C. J. Edwards made his Cubs organizational as well as his Class High A debut and he was impressive. The lanky right-hander fanned the first seven Cardinal hitters he faced, five swinging. He worked five innings and the only hit was as infield single, and Palm Beach didn't hit the ball out of the infield. Slinging a fastball in the mid-90s and a breaking ball in the low 80s, Edwards dominated the 17 hitters he faced, getting eight on strikes, and three to foul out. The 21-year-old threw 63 pitches, 41 for strikes…..Lendy Castillo (1-0 1.80 ERA/1.40 WHIP) recorded his first win at Daytona allowing an unearned run in three innings. Castillo gave up a hit and three walks with three strikeouts…..Austin Reed (1-0 4.25/1.47) earned his third save pitching the ninth.
Cubs Notes: Zeke DeVoss went from April 30 to May 22 without even attempting a SB and didn't swipe a bag until June 7 when he stole three. Since then, 20 SB and caught once. He also lowered his strikeout percentage from 20.3% in 2012 to 18.1%…...Cubs RHP Scott Baker will make his fourth rehab start on Monday for Daytona.
Low A—Kane County 6, Peoria 3
Kane County (40-60) scored four times in the third and beat Peoria (56-46) to even the series.
At the Plate: Rock Shoulders (.260/.357/.479) had the big hit of the game with a bases clearing double to plate three runs in the third. Shoulders was 2-5 and is nine for his last 20. Giuseppe Papaccio (.244/.306/.289) batted leadoff and went 2-5 and scored twice. Jeimer Candelario (.251/.337/.377) was 2-4 with a RBI and a walk while Albert Almora (.333/.379/.482) went 2-5 with a run. Daniel Vogelbach (.291/.365/.457) had a RBI going 1-2 with two walks.
On the Mound: Armando Rivero (0-0 6.06 ERA/1.59 WHIP) is settling in as the Cuban fireballer earned his first pro save and extended his scoreless streak to 7.2 innings with 14 strikeouts. The 6-foot-4 right-hander blanked the Chiefs the final two frames fanning five with one walk. Rivero had three tough outings in his first six games but since then has been dominating…...One pitcher the Cubs are counting on is Juan Paniagua (0-2 8.22/2.87), who made his third appearance for the Cougars. The right-hander had problems getting into the U.S. due to visa issues and threw four games in the DSL while he waited. Paniagua had problems finding the strike zone Sunday walking five and allowing three hits in two innings. The Chiefs scored two runs and he didn't strikeout a hitter…..Nathan Dorris (5-3 2.99/1.34) got the win pitching out of a jam in the third and adding another shutout inning with two strikeouts….. RHP Starling Peralta worked three scoreless innings after joining the team today. He allowed two hits and a walk and fanned two.
Cougars Notes: LHP Michael Heesch (3-8 3.82 ERA/1.33 WHIP/ 96.2 IP) was placed on the disabled list and RHP Starling Peralta was assigned to Kane County from Mesa. Peralta has been in Arizona on rehab from Daytona after getting injured in May.
Short-Season—Boise 3, Spokane 1
The arm of Dillon Maples and the bat of Kris Bryant gave Boise (24-20) the win over Spokane (22-22).
At the Plate: Kris Bryant walloped his second homer of the season, a two-run blast in the fourth, and the first-round pick added a sacrifice fly in the seventh to knock in all three Boise runs. Daniel Lockhart, Yasiel Balaguert and Jordan Hankins all had two singles.
On the Mound: Dillon Maples (2-0 1.38 ERA) threw five strong innings allowing a run on five hits with five strikeouts for the win. For the second straight game, Maples didn't walk a hitter. In 34.2 IP at Kane County, Maples walked 31…..Corbin Hoffner (2-0 1.21) celebrated his 20th birthday two days early tossing three scoreless innings with a pair of strikeouts. The 6-foot-5 right-hander has not allowed a run in his last 14 innings.……….Tyler Bremer (0-2 2.50) must have seen highlights of the Cubs-Giants game Saturday night as the right-hander loaded the bases in the ninth and promptly struck out the side for his fourth save.
Hawks Notes: Shawon Dunston missed his seventh straight game after colliding with teammate Chris Bote and hurting his quad. Jacob Hannemann is still out of the lineup after a wrist injury and is also recouping from an ankle sprain.
Arizona Rookie League—Diamondbacks 13, Cubs 3
The Diamondbacks (16-14) scored six times in the third and whipped the Cubs (14-17).
At the Plate: Kevin Brown delivered a two-run single and Jessie Hodges added a RBI double in the Cubs three-run fourth. Jeffrey Baez was 2-4 with a run and is hitting .284 with a four-game hitting streak (8-16). Charcer Burks, the first high school product selected in the 2013 draft (9th round) had his second straight multi-hit game going 2-4 with a double, his first career extra-base hit. The 18-year-old is hitting .263 in 12 games. Brett Jackson was 0-4 and is 1-14 during his rehab.
On the Mound: Erick Leal, (0-2 3.46 ERA) acquired in the Tony Campana trade, got the majority of the work Sunday night tossing four innings. The right-hander allowed seven hits, three run (one earned), fanned three, and faced 20 hitters, getting eight ground ball outs…..Jose Arias, rehab from Kane County, got the start surrendering three runs on three hits and two walks in 1.2 frames….. RHP Ethan Ellis gave up six runs on five hits and a walk in an inning…..Luis Villalba (0-0 1.69) got the final four outs allowing a hit.
Dominican Summer League—Cubs
Had the day off
Venezuelan Summer League—Cubs
Had the day off.


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This is a recent card we made at my uppity-uppity-upline, Glenda's, group meeting. We stamped on the canvas sheets that are currently in the Spring mini catalog.
Posted at Apr 23, 2013 09:36 PM | Comments [0]
Here are 5 of the 6 cards we made at last month's Basic Card Class -
Be sure to join us at the next Nasic Card Class! We make 6 wonderful, quick cards for $15!
Posted at Apr 18, 2013 09:59 PM | Comments [0]
Sale-a-Bration Stamp Camp Cards Part 3
Here is the final set of cards from my Farewell Sale-a-Bration Stamp Camp - CASED from Ilina Crouse. All 5 cards use the free Sycamore Street Designer Paper with matching button & ribbon pack and Madison Avenue stamp set.
Posted at Mar 23, 2013 11:41 PM | Comments [0]
Sale-a-Bration Stamp Camp Cards Part 2
Here's another set of cards we made at my recent Farewell to Sale-a-Bration Stamp Camp. All of the cards in this set were created with the free Sale-a-Bration stamp set called Bloomin' Marvelous.
Posted at Mar 23, 2013 12:19 AM | Comments [0]
Sale-a-Bration Stamp Camp Cards Part 1
Last Sunday was my Farewell Sale-a-Bration Stamp Camp. The ladies all made a TON of cards and I'll show them over the next couple of days. They made 5 card SETS using 5 of the Sale-a-Bration exclusive stamp sets.
This set of three full sized cards uses the stamp set called Feeling Sentimental.
This sweet little set of 3x3 love notes uses the free Sale-a-Bration stamp set called Pretty Petites and the free matching punch.
This fun colorful set of tiny cards uses the free Sale-a-Bration stamp set called Patterned Occasions along with the free designer paper pack called Sycamore Street.
Posted at Mar 21, 2013 10:11 PM | Comments [0]
Sale-a-Bration (Stampin' Up's biggest sale time of the year) comes to a close this week. So, I thought I'd show you some final samples using some of the free Sale-a-Bration goodies.
This cute little 3x3 card uses the Patterned Occasions stamp set and the Sycamore Street designer paper that you can earn for free.
Another 3x3 card - this one CASED from Angela McKay. It uses the Sycamore Street designer paper again, along with the free Sale-a-Bration ribbon and the free Madison Avenue stamp set.
This beauty was CASED from Julie Davison. It uses lots of free Sale-a-Bration goodies too - the Vintage Verses stamp set, the Vintage Faceted Buttons, and again the Sycamore Street designer paper!
Posted at Mar 18, 2013 11:34 PM | Comments [0]
Basic Card Class is coming up on March 21st. You may RSVP for the 2-4pm session or the 7-9pm session. Everyone makes 6 quick, but fabulous cards for $15 (or for free with a $25 order). And if you bring a new adult friend to stamp, you get to make double the cards! Here are some of the cards from last month's class -
This card looks great done up in any of the In Colors.
I am so in love with this stamp set called "Blooming With Kindness".
CASED from Dawn Olchefske
These final two cards were both CASED from the talented Mindy Backes.
Posted at Mar 12, 2013 09:41 PM | Comments [0]
Here are three cards with the great single stamp called "Just Thinking".
CASED from Angela McKay
CASED from Angie Juda
These bottom two cards use Stampin' Up's Core'dinations cardstock. It's super cool stuff. You emboss it, rub a sanding block over it, and the lighter core of the cardstock shows through!
Posted at Mar 11, 2013 09:59 PM | Comments [0]
Wow! Stamping Class is coming up, so RSVP quickly. At this class we make 3 amazing projects that will "wow" your recepients. They usually teach a cool technique or neat fold or use a fun, new product. Class cost is $10 or free with a minimum $25 order placed at class. You may choose between Sunday, March 10th at 2pm or Monday, March 11th at 7pm. You may also choose to take Scrapbooking Class at the same time. Here are last month's Wow! Stamping Class projects -
CASED from Becky Roberts
This great card was used to teach the chalkboard technique, which is currently all the rage in the crafting world.
CASED from LeeAnn Greff
When you pull on the white lid of this coffee cup card, it reveals a gift card holder. Perfect for giving a Starbucks gift card to someone special!
CASED from Deb Valder
We embossed the beautiful Swallowtail stamp with vanilla embossing powder and then sponged our springy ink colors all around. So pretty!
Posted at Mar 04, 2013 12:13 AM | Comments [0]


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Snorri the SealBy Dan Piepenbring
It's Banned Books Week, and everyone is rallying around the classics: your Gatsbys, your Catcher in the Ryes, your Mockingbirds and Lady Chatterleys. No one is giving any love to Snorri the Seal—to my eye one of the handsomest books ever to face censorship.
Snorri is a Norwegian children's book written and illustrated by Frithjof Sælen. Published in 1941, during the Nazi occupation of Norway, it tells the story of "the vainest little seal in the Arctic Ocean"—that's our Snorri!—who whiles away his seal-days delighting in his own good looks. And who wouldn't, with a luxurious coat like his? He's so self-absorbed that he fails to see trouble on the horizon in the form of Brummelab, a distinctly Soviet polar bear. Read More


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8 p.m. Tuesday — "How to Survive the Zombie Apocalypse," a talk by Max Brooks, author of The Zombie Survival Guide and World War Z, in the Silver Eagle Suite at the UNT Union, one block west of Welch and West Prairie streets. A book signing follows. Part of UNT's Fine Arts Series. Tickets are $20 for the general public; $10 for UNT faculty, staff and Alumni Association members; and free for UNT students. Call 940-565-3805 or visit http://untuniontickets.universitytickets.com .
10 a.m. to 4 p.m. Oct. 13 — "Pumpkin Patch Mania" at the Denton Civic Center, 321 E. McKinney St., for kids ages 5 to 11. Kids will create Halloween crafts before heading to a local pumpkin patch for a hay ride, bounce house, petting zoo and more. The fee is $20 per child. Register by Oct. 11 by visiting www.dentonparks.com or by calling 940-349-7275.
12:15 to 1 p.m. Oct. 18 — "Haunted Denton," a virtual tour of Denton's reportedly haunted places by librarian Laura Douglas, in the Commissioners Courtroom at the Courthouse on the Square, 110 W. Hickory St. Free. Visit http://dentoncounty.com/chos .
6:15 p.m. Oct. 18 — "A Night of Mystery on Hospitality Hill," a progressive dinner with stories by Tejas Storytellers, benefiting the United Way of Denton County. Participants will meet at the Courtyard Marriott, 2800 Colorado Blvd., proceed to the Hilton Garden Hill and finish at the Best Western Premier. Cost is $60 per person or $100 per couple. For tickets, call 940-566-5851, ext. 102. Visit www.unitedwaydenton.org or e-mail email@example.com .
6 to 8 p.m. Oct. 19 — Halloween Harvest at Denia Recreation Center, 1001 Parvin St. Event includes carnival games, black-light games, a bounce house, a costume contest and a storytelling hayride. The carnival is free; rock climbing costs $1, and low-priced concessions will be available. Register at the door by 7 p.m. for the costume contest. Winners will be announced at 7:15 p.m. Call 940-349-8285.
8 a.m. Oct. 20 — Jack-O-Lantern Jog, a 5K race and one-mile fun walk, at North Lakes Park, 2001 W. Windsor Drive. Check-in starts at 7 a.m. Register early for $15 by 4 p.m. Oct. 18. Registration at the event will be $20. Entry fee includes a T-shirt, snacks and drinks. Visit www.dentonparks.com or call 940-349-8287.
6 to 8:30 p.m. Oct. 26 — Denton Green Mile presents a free community costume bike ride for all ages. Gather in costume on the Square at 110 W. Hickory St. for a one-mile ride. Pedestrians and wheelchair users are welcome to join the event. Free. An after-party with music will take place at the Love Shack, 115 E. Hickory St. Visit www.dentongreenmile.info or www.facebook.com/DentonGreenMile .
9 a.m. to 6 p.m. Oct. 27 — Selwyn Pumpkin Fest at Selwyn College Preparatory School, 3333 W. University Drive. Festival includes a car show, music, a health fair, a costume contest, children's activities, craft booths, food vendors and more. A 5K run starts at 7 a.m., followed by the Pumpkin Chase Fun Run at 8 a.m. Admission is free. Tickets for activities and concessions cost 50 cents each. Call 940-382-6771, or visit www.selwynschool.com or www.facebook.com/SelwynPumpkinFest .
11 a.m. to 10 p.m. Oct. 27 — Denton's Day of the Dead festival all along Industrial Street in downtown. Enjoy booths, children's games, a costume parade, live music, and the all-ages Halloween musical Cirque du Horror at Dan's Silverleaf 103 Industrial St. Admission to festival is free; coffin races and musical include fees. Visit http://on.fb.me/SVutP2 .
Weekends through Oct. 28 —Screams Halloween park, opens at 7:30 p.m. on weekends at 2511 FM66 in Waxahachie. Admission is $24.99. For more information, including ticket discounts, visit www.screamspark.com or call 972-938-3247.


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Sony will be bringing a white 500GB PlayStation 3 to the US later this month. Beginning on January 27, players will be able to purchase the Classic White PS3 Instant Game Collection Bundle for $299.99. In addition to the new color and larger hard drive, the set also includes a one-year subscription to PlayStation Plus, which currently provides cloud storage for saves and a selection of 12 PS3 games, six PS Vita games, and various discounts that is updated monthly.
Official Site: PlayStation.com – PS3 Classic White Bundle


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GM Leads Innovation With Most Patents
Smug journalists across the internet are poking fun at the possibility that President Barack Obama might have referred to the 2013 Shelby GT500 Mustang as "sick" during his visit to the Washington D.C. Auto Show.
True or false, his remarks about the muscle car don't really matter. What's slightly more significant is the speech he made to herald General Motors' return to the throne as the world's highest volume automaker.
While it isn't surprising that the President would want to talk about something like that, it is a good chance to point out that GM is doing more than taking the Costco approach to selling cars.
In fact, GM is leading more than just the number of vehicles sold. They're also the industry's top innovator, according to The Patent Board. This is actually the fourth consecutive quarter that the Detroit giant can claim that title. An impressive 1,123 U.S. patents were granted to the company in 2011 for global product engineering, global powertrain engineering, global research and development and OnStar organizations.
It's interesting because we don't always think of GM when imagining who will come out with the latest breaking tech or engineering feats, yet they emerged victorious over 183 other firms. It seems like most of the automotive wizardry starts overseas in Europe and makes its way to domestic vehicles a little while later.
Blind spot detection is a great example of that. Volvo was the first to introduce it, but companies like GM and Ford are on board with the bandwagon.
Among GM's recent patents, there is technology for quieter brakes, better OnStar voice recognition and something called eAssist Thermal Management which controls engine shutoff to ensure occupant comfort in extremely hot or cold weather.
That begs the question: what's next from some of the greatest minds in Michigan?


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MACHIASPORT – The Rev. Betty E. Seidle passed away Nov. 6, 2012, at a Bangor hospital. Betty was born Dec. 7, 1938, in Philidelphia, daughter of the late Charles Stanley and Hattie Elizabeth Seidle.
Betty received her education through Temple University and was a retired elementary school teacher. She taught for 20 years in the Hicksville, N.Y., school system before making the coast of Maine her home. Betty was a proficient musician and music was always a joy for her whether playing or listening. She played the French horn, piano and keyboard. For a number of years Betty shared her musical gifts with residents of many longterm care and rehabilitation homes in Maine and Canada. She was also a certified nursing assistant working at Down East Community Hospital and a volunteer ombudsman for state programs. Betty's love of our Lord led her to study in preparation for the deaconate in the Episcopal church. On June 19, 2004, she was ordained to the Sacred Order of Deacons at St. John's Episcopal Church, Bangor. Betty was assigned by the Bishop of the Episcopal Diocese of Maine to serve at St. Aidan's Episcopal Church, Machias, which she did faithfully until the time of her death.
Betty is survived by her two friends of 40 years, Betty Phillips and Pam Miller, both of Machiasport; sister, Kim Terra Nova; and niece, Jessica Terra Nova, both of Colorado. She leaves behind her beloved great dane, Domino; and our chocolate cocker, Logan.
There will be a memorial service at a later date. In lieu of flowers, memorial donations may be made to Machias Food Pantry.


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Fullback Ajagbe shines when number is called
Published: Monday, September 2, 2013 at 6:01 a.m.
Last Modified: Monday, September 2, 2013 at 12:02 a.m.
His last name is pronounced uh-JOB-ee.
You won't hear his teammates saying it, though.
They call him the 'Nigerian Nightmare.'
"He's African," Mack Brown said, "and he's a nightmare."
The Florida running back faced Gideon Ajagbe in practice for three years when he played linebacker for the Gators.
This past spring, Ajagbe moved over to the offensive side of the ball at fullback. According to Brown, the 6-foot-2, 244-pounder gave his old position group nightmares throughout fall training camp.
"All linebackers felt some pain from Gideon at some time during camp," Brown said. "He's a strong guy."
In Saturday's 24-6 season-opening win over Toledo, Ajagbe showed off his physicality — and some pass-catching skills as well.
On Florida's scoring drive in the third quarter, quarterback Jeff Driskel found him open in the flat on second-and-10 at the Toledo 22-yard line. Ajagbe was immediately met at the line of scrimmage by a Rockets defender, but broke the tackle with a spin move and rumbled ahead 12 yards for a first down.
"He made a guy miss," Driskel said. "It could have been an easy two-yard gain. Instead, he turned it into a big play."
Two downs later — on third-and-goal — Ajagbe hauled in a four-yard touchdown reception on a play-action pass from Driskel.
"He did a good job on the touchdown of really stretching the defense and creating a good window for me," Driskel said. "He's a big body, he has good range and he has good hands. He's a target I like throwing to."
With Hunter Joyer still slowed by a hamstring injury, Ajagbe made the first start of his career.
"I haven't really played much these last three years," he said. "So for me to be a starter, it was a blessing. It just felt good to know the coaches trusted me. The opportunity to play with my teammates and be a big contributor, it was fun."
Moving forward, Ajagbe feels he can continue to be a factor through the air and not just a blocker.
"I believe I can be a double threat," he said. "I have pretty good hands. I've been practicing and doing real well catching balls in camp.
"I think when the coaches saw that, they thought, 'OK, we can use him in the passing game.' It just added more dimensions."
Fullbacks haven't scored many touchdowns for the Gators in years past, but Ajagbe may shake up the status quo this season.
"He's done an outstanding job blocking, protecting and catching the football," UF coach Will Muschamp said. "He'll throw his face in the fan. He's a guy that's really blossomed in the position. That's why you always try and cross-train guys at different spots and see what they can do, and he did a fantastic job.
"We've got a lot of confidence in Gideon. As good of a player as we think Hunter is, we think Gideon is a good player as well."
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


text: If we are going to feed 9 billion people by 2050, we want to do it using existing farmland, because using more land for farming would be a tragedy, Mike Mack, CEO of Syngenta, told CNBC Thursday. Although the crops are safe, genetically modified food wonâ??t be adopted in the euro zone because of opposition, Mack said.


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text:
Name Variations Edit
- strozzapreti
About Strozzapreti Edit
Wikipedia Article About Strozzapreti on Wikipedia
Strozzapreti is a kind of pasta. Its name is from the Italian for "priest choker", and is said to reflect the cook's wishes that priests choke on the food.
The pasta's shape that resembles a rolled towel.


text:
Julia Roberts
News about Julia Roberts, including commentary and archival articles published in The New York Times.
Highlights From the Archives
Hello, Again
Julia Roberts returns to the big screen as a leading lady in "Duplicity," now on DVD.February 10, 2009 moviesNews
Julia Roberts Is Coming to TV. We Have Some Ideas for Her.
The movie star will be adapting a novel, "Today Will Be Different," for the small screen. But could she survive the Upside Down?...
December 16, 2016, Friday
At the Cannes Film Festival With Julia Roberts and Jessica Chastain
The stylist Elizabeth Stewart gives T a look inside her whirlwind week preparing both stars for the red carpet....
May 18, 2016, Wednesday
'Captain America: Civil War' Tops North American Box Office
"Money Monster," which was released Friday, came in third, but the studio behind it was very happy with that result....
May 16, 2016, Monday
Review: In 'Money Monster,' a Broke Investor Holds a Grudge and a Gun
George Clooney plays a financial news talk-show host, and Julia Roberts is his producer in this self-assured hostage drama....
May 13, 2016, Friday
Review: 'Mother's Day' Is a Goopy, Glossy Sentimental Mess
Jennifer Aniston, Kate Hudson and Julia Roberts star in this holiday-themed film that generates inadvertent laughs and has predictable plotlines....
April 29, 2016, Friday
M.T.A., as Victim, Wants Transit Thief's Profits From Hollywood Movie Deal
The transportation authority said it would move to recover any money Darius McCollum may make from selling the story of his thefts of trains and buses for a film in development starring Julia Roberts....
March 22, 2016, Tuesday
Review: 'Secret in Their Eyes,' a 13-Year Hunt for a Killer
This remake of an Argentine Oscar-winning film centers on the murder of the daughter of an investigator for the Los Angeles District Attorney's Office....
November 19, 2015, Thursday
Julia Roberts, in 'Secret in Their Eyes,' Turns Her Famous Smile to Grief
The star talks about working with her husband on "Secret in Their Eyes," gender disparity in Hollywood and her coming movie with George Clooney....
November 15, 2015, Sunday
Duchess Kate's Visit, Julia Roberts's New Gig and Leonardo DiCaprio's Mob of Models
Plus, Taylor Swift's BFFs, the rise of beard baubles and more from the week in style....
December 12, 2014, Friday
Nature Talks Back, and Sounds a Lot like Edward Norton
Edward Norton, Julia Roberts and other actors give voice to soils, seas and other natural assets....
October 14, 2014, Tuesday
Rss Feeds On Julia Roberts
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Receive My Alerts e-mails on topics covered on this page.More Alerts >>


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As regards her leading man, Gabby Concepcion, whom she had worked with many times in the past, Maricel Soriano admitted that their chemistry and rapport extend beyond the silver screen.
Napakaganda ng bonding naman. Andami naming napag uusapan, at yung usap namin, may depth na hindi kagaya dati na panay fancy talk lang. Now we talk about life, mga anak namin at even ang mga pelikula namin before at iba pang mga nakatutuwang bagay, she said.


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text:
Stanley Krippner, Adam J Rock, Julia Beischel, Harris L Friedman and Cheryl L Fracasso (Editors) Advances in Parapsychological Research 9. McFarland, 2013.
It is sixteen years since the previous Advances in Parapsychological Research, volumes of which used to be produced every three or four years, and this volume is substantially slimmer than its predecessors. Of the ten papers published here, only two really summarise advances in mainstream parapsychology; Sherwood and Roe's study of post-Maimonides dream studies programmes, and Modestino's survey of physiological responses as unconscious measures of psi.
The large majority of the studies reviewed in the former were conducted in the twentieth century, some as much as thirty years ago. The future might lie with the physiological response however, and this seems to have the possibility of avoiding the ambiguities of subjective judging that one gets in the former, yet I get the sense that even here things are made unnecessarily complicated. Both these papers are highly technical in parts, and rely much on statistical analyses.
The large majority of the studies reviewed in the former were conducted in the twentieth century, some as much as thirty years ago. The future might lie with the physiological response however, and this seems to have the possibility of avoiding the ambiguities of subjective judging that one gets in the former, yet I get the sense that even here things are made unnecessarily complicated. Both these papers are highly technical in parts, and rely much on statistical analyses.
Roger Nelson's paper on The Global Consciousness project also relies on statistics to analyse supposed anomalies in the production of random numbers associated with global events, in this study mainly 9/11. It still remains as clear as mud exactly what, in ordinary lay terms these anomalies are, but I am willing to accept that they are 'anomalies' of some sort. If these had started suddenly moments after the first plane struck then that would have been an interesting coincidence at least, but they actually start about four hours beforehand. This is explained as precognition, but of course if you start invoking precognition and retrocognition you will be able to fit the anomalies to anything. Given the wide definition of these events (not just major disasters, but pop concerts, political rallies, wars and rumours of wars, meditations, religious festivals and anything else you might come across) it seems doubtful that even a week goes by without some 'event' somewhere in the world, only a minority of which would be reported in the western media. An anomaly over the last few days might be correlated to the Mediterranean refugee boat disaster, the Phillipines typhoon and/or the England-Germany football match.
Several of the papers are of more general philosophical character, though still heavily laden with technical jargon; the lay person cannot get much enthused about a study of 'Frequentist, Bayesian and [I think 'or' is actually meant in the context rather than 'and'] Quantum Modelling of Ganzfield ESP' or 'Operationalizing Psi Conducive Altered States'. All this technicality because everything depends on barely detectable statistical anomalies.
If that level of obscurity is not enough for you, you can always invent new jargon, try 'psychopraxia' a term invented by Australian parapsychologist Michael Thalbourne. In his paper his student Lance Storm compares psychopraxia to 'Psi Mediated Instrumental Response' and synchronicity as models for psi. I suspect it would be just as helpful to compare samifarts, boojums and snarks as explanations, all being as meaningless as one another. One can't help feeling that as mainstream science often uses lots of specialist technical jargon, parapsychologists think, as a sort of scientific cargo cult, that if they use enough technical sounding jargon they will become scientists.
The need to escape from this off-putting jargon and technicalism, so as to actually engage with a wider public is one of the points made by William Braud in his concluding essay 'Expanding Psi Research', however outside this, and the obvious point that people who take part in experiments should be treated as people not guinea pigs, many of his suggestions mean abandoning science all together. He might have a point, human beings may be just complicated ever to be scientifically studied, but the price will be that all thoughts of recognition of psychical research by mainstream science will, have to be abandoned.
Another reason for the jargon may be to actually hide what they really think. When their claims become expressed in compressible terms, one can see how radical some of these are. Stephen Braude (no relation, I think, of William) in his obituary of Jule Eisenbud points to his work with Ted Serios and his psychic photos, not a claim likely to gain support among mainstream scientists anytime soon.
Nor are the claims in the paper on surrogate treatments using 'energy psychology'. Now energy psychology is about treating people's psychological problems by tapping them on acupuncture points while humming. Surrogate energy means you tap yourself and hum to yourself to cure someone else, who may not even be in the room. Here we have it all; claims of near miraculous sudden cures by an unknown mechanism, largely based on personal testimonial, complete with irrelevant references to entanglement, the Higgs Boson, zero point energy and string theory, and with references which quote from scientific, pseudo-scientific, popular and frankly promotional material quite promiscuously. Now you know that if some sceptical journal was to do a knocking piece on this, parapsychologists would rush over themselves to complain that serious parapsychology was being unfairly tarred with the brush of quackery. Yet this appears in Advances of Parapsychology. – Peter Rogerson


text:
That SO COOL.Ā Now I want to get an army of us together all dressed as Tron dorks, and start a Frisbee sports team!

I was thinking about trying something similar with UV LED's and florescent pigment.Ā This would lend its self well to sunlight but maybe less well in darkness.Ā Thoughts?

On Mon, Jan 3, 2011 at 12:55 PM, Laura Khalil <firstname.lastname@example.com> wrote:

 Sean that's an awesome suit! Congratulations on making something really cool and thanks for sharing something constructive (and related to hacking) with the list.

You've got my vote.

Laura

On Mon, Jan 3, 2011 at 11:11 AM, Sean Cusack <firstname.lastname@example.com> wrote:

 Helllllloooo Noisebridge!

As some of you may know - I love making dumb costumes. The shinier it is, the more I'm interested in it. For the new Tron movie, I made a Tron suit (in the nouveau style) that is entirely lit by LEDs (about 190 of them). You can't see the pesky points, and but you do have an epic, diffuse, overly bright white glow. I wrote an instructables article on how to do it, and even if you aren't the slightest bit interested in Tron, but you are interested in wearable electronics, I'd say to head to the below link and check it out! Hopefully you at least get some ideas on how to get 190 LEDs onto an easily washable outfit quickly :).

BTW, its up for the laser cutter contest, so if you love it - *vote for it to win it*! I can't put a laser cutter in my apartment, so that means it'll be coming to Noisebridge if I win it (scouts honor and pinky swear!)

http://www.instructables.com/id/LED-lit-Tron-v20-suit/

Sean

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text:
Shed some light on your campaign with this light bulb promotional stress reliever.
The original Press n' Stick Custom Calendar - named one of the five most innovative products for over 100 years in Promotional Products.
The Light Bulb Promotional Jar Opener is a bright idea for your next promotion.


text:
|René Nyffenegger's collection of things on the web
René Nyffenegger on Oracle - Most wanted - Feedback
- Follow @renenyffenegger
Loading dates with external tables in Oracle
The following file contains some holidays for the year 2007:
New Year's Day,Jan 1 2007 Inauguration Day, "Martin L. King, Jr. Day",Jan 15 2007 President's Day,Feb 19 2007 Memorial Day,May 28 2007 Independance Day,Jul 4 2007 Labor Day,Sep 3 2007 Columbus Day,Oct 8 2007 Veteran's Day,Nov 11 2007 Thankgsiving Day,Nov 22 2007 Christmas Day,Dec 25 2007
In order to access it from Oracle, a directory is created:
create or replace directory c_temp as 'c:\temp';
Now, the external table can be created. The records are seperated by commas (fields terminated by ','). However, some holiday names (Martin L. King, Jr. Day) contain a comma, so they are enclosed with " in the file. Accordingly, the access parameters have a
optionally enclosed by '"'.
Also, the date format (or date mask) is specified: Mon dd yyyy which specifies that a date consists of the first three letters of a month's name followed by a space followed by a two digit number specifying the day again followed by a space followed by a four digit number specifying the year.
drop table holidays; create table holidays ( name varchar2(30), day date ) organization external ( type oracle_loader default directory c_temp access parameters ( records delimited by 0x'0a' fields terminated by ',' optionally enclosed by '"' missing field values are null ( "NAME", "DAY" DATE "Mon dd yyyy" ) ) location ('holidays.txt') ) reject limit unlimited;
Now, the table can be selected from:
select * from holidays;
NAME DAY -------------------------------------------------- ------------------- New Year's Day 01.01.2007 00:00:00 Inauguration Day Martin L. King, Jr. Day 15.01.2007 00:00:00 President's Day 19.02.2007 00:00:00 Memorial Day 28.05.2007 00:00:00 Independance Day 04.07.2007 00:00:00 Labor Day 03.09.2007 00:00:00 Columbus Day 08.10.2007 00:00:00 Veteran's Day 11.11.2007 00:00:00 Thankgsiving Day 22.11.2007 00:00:00 Christmas Day 25.12.2007 00:00:00
See also this link.


text:
Researchers have created a Cupid so small that each arm is the width of a human hair.
This tiny Valentine is an example of big technology. Just a few hundred nanometers from foot to bow (a nanometer is a billionth of a meter), this Cupid is made from carbon nanotubes in a process that has been used in fields as diverse as mining and health care.
To make the tiny Cupid, physics students at Brigham Young University (BYU) first created the bow-wielding cherub shape with microscopic iron beads, Discovery News reported.
They then blasted the beads with a puff of heated gas, which triggers the microscopic beads to sprout a tiny forest of into carbon nanotubes only 20 atoms across.
The resulting structure is as delicate as new love.
"Blowing on it or touching it would destroy it," BYU physics professor Robert Davis said in a statement.
Davis and his colleagues have ways to take the technology past the realm of fragile Valentines, however.
Along with BYU physicist Richard Vanfleet, Davis has developed methods to strengthen the nanotube structures by coating them with metals and other materials.
One application is building itsy-bitsy nanofilters with great precision - these filters have holes about a tenth the circumference of a human hair, each perfectly spaced. Such nano-filters can be used in compressed gas systems in mining, health care and scuba diving, Davis said. (ANI)


text:
Dr. Egon R. Casanova M.D.
Internal Medicine – Hematology
Assistant Professor of Hematology
Pathophysiology Department
Faculty of Biologic Science
University of Concepcion
Concepcion – Chile
Non-Hodgkin lymphoma (NHL) is a heterogeneous disease including a large variety of different diseases. The broad category of NHL includes indolent as well as aggressive lymphomas. MALT lymphomas (Mucosa Associated Lymphoid Tissue) lymphoma arise in the extranodal, mucosal lymphoid tissue and represent as many as 7.6% of all lymphomas. This type of NHL has only been recognized as a distinct entity in recent years (1). It may affect extranodal structures such as the eye, gastrointestinal tract (GIT) specially the stomach, thymus, larynx, pharynx, lungs and salivary glands. The NHL-MALT type is generally of low grade and has indolent course. However, about 10% of cases have regional lymph nodes and bone marrow involvement.
NHL-MALT type arises in areas where chronic inflammation is often present such as GIT, respiratory tract (BALT: Bronchus-Associated Lymphoid Tissue lymphoma), salivary and lachrymal glands. Most of those organs lack native lymphoid tissue but acquire MALT in close association with chronic inflammation or autoimmune processes being the typical examples NHL-MALT type in the stomach associated with H. Pylori and parotid MALToma with Sjögren syndrome. The frequency of NHL-MALT type is in GIT 50%, respiratory tract 10%, head and neck 10% (orbit, sinuses, thyroid gland, salivary glands and Waldeyer's ring) and others 30% (kidney, urogenital tract as prostate, uterus and Fallopian tubes, liver, breast, pancreas, gallbladder).
Salivary glands involvement by NHL-MALT is associated in 10% of cases with Sjögren syndrome. Parotid is the most frequently involved salivary gland (70%), followed by submaxilar glands (30%). Primary parotid NHL represents 1% of all NHL and 8.6% of all parotid neoplasm (2). The presence of intraglandular lymph nodes are common in parotid glands. NHL arising from these lymph nodes are not MALT type but low-grade follicular lymphoma that typically does not involve the salivary tissue.
The goal of this paper is to present a clinical case of parotid gland NHL-MALT type reviewing our present state-of-the-art of our knowledge on the molecular biology of maltomas.
A 40-year-old married woman, who had been well until three months earlier when a painless slow growing lump in the right parotid gland appeared. There was no history of fever, sweats or weight loss but she had a history of rheumatoid arthritis and Sjögren syndrome five years earlier. She is moderate smoker (10-12 cigarettes/day for 20 years) and have no allergy and no alcohol intake. Normal menstruation. On physical examination a 4 cm in diameter, non tender, rubbery consistency and solitary parotid tumor was found. No lymphadenopathy and Waldeyer's ring compromise was present. The lungs, heart, and breasts were normal. The liver and spleen were not felt, and no abdominal tenderness or mass was detected. The extremities were normal. Parotid glands echotomography showed a solid substitution within the right parotid confirmed with computed tomography (CAT) scan of the neck. A tumorectomy was performed. Biopsy: diffuse infiltration of small monocytoid and centrocytic lymphocytes that distorted the normal arquitecture of the parotid gland. Pan B markers; CD19, CD20 (+) in 80% of cells, Pan T markers CD3, CD5 (+) in 20% of cells, cyclin D1 (-), and Bcl-2 (+), concluding in Malignant Diffuse non-Hodgkin Lymphoma MALT-type. The values for Beta-2-microglobulin, plasma uric acid, LDH, VDRL, blood sugar, creatinine, C-reactive protein, HIV, TNF-alpha, IL-6, TSH, ANA and complete blood count were all normal. Rheumatoid factor: 228 IU/ml (<20), VHS: 41 mm/h, IgA, IgM, IgE, C'3, C'4 all normal, IgG: 2815 mg/dl (700-1800), plasma protein electrophoresis policlonal increase of gamma globulin, immunoelectrophoresis of heavy and light chains normal (increase normal IgG). ECG, plain chest-X-ray, bone marrow biopsy, chest and abdominal CAT scans all normal. Reticulocytes count: 0.5%, Ferritin 13 ng/ml, blood iron 48 ug/dl, transferrin 220 mg/dl, transferrin saturation 21%. Diagnosis: 1) Primary Non-Hodgkin lymphoma-MALT-Type Stage I-E of right parotid. 2) Collagen-vascular disease: Rheumatoid Arthritis, Sjögren syndrome. 3) Chronic tabaquism. The patient was treated with local-regional radiotherapy (4500 cGy) with total recovery. Two years later she consults for the appearance of spots and ecchymoses in the skin of the trunk and in both upper and low extremities. On examination blood pressure was 120/70, pulse 68x' and no fever. The parotid glands were normal. She presented right epistaxis and petechiae on the body, no enlarged lymph nodes and no liver or spleen felt. Complete blood count Hto: 38.3%, Hb: 12.8 g/dl, MCV and MCHC normal, white blood cell count (WBC) 2700/ul, differential 1-1-0-0-4-52-39-3 and platelets count 4000/ul. A diagnosis of autoimmune thrombocytopenic purpura was made receiving the patient a course of prednisone (60 mg/day) recovering the WBC and platelet count to normal 16 days later. At present, five years later, she is in well condition with abscense of parotid tumor.
Primary NHL of the salivary gland is an uncommon tumor and within its rarity most often occurs in the parotid gland (70%) and belongs to MALT type (3). NHL-MALT-type of the parotid gland generally is localized or occasionally may be one component of a disseminated lymphoma (4,5). MALT are the extra-nodal equivalent of monocytoid (marginal zone) B-cell lymphomas that occur in lymphoid organs such as the lymph node. MALT lymphomas regardless of organs of origin, have similar clinicopathological and molecular features; they are generally indolent, tends to remain localized for long period of time even without treatment and eventually the tumor may disseminate or transform to a higher grade. In the parotid gland this low-grade MALT lymphoma is rare usually arising in a background of benign lymphoepithelial lesion or myoepithelial sialadenitis that is associated with collagen-vascular disease specially with the autoimmune disease Sjögren's syndrome, however, occasionally may develops in patients who do not have a history of autoimmune disease (5,6,7,8). It has been reported that 80-85% of primary parotid gland tumors are benign and 15-20% are malignant and within this, 1-5% are malignant lymphomas. The histological distinction of myoepithelial sialadenitis from low-grade B-cell MALT lymphoma can be a difficult diagnostic challenge. Immunophenotyping by flow cytometry analysis may be useful in showing an aberrant phenotype or immunoglobulin light-chain restriction, may help to support a diagnosis of malignant lymphoma in most cases. Molecular genetic analysis for immunoglobulin gene rearrangements also may be useful in showing monoclonality (5,8,9). Chronic inflammatory process other than Sjögren's syndrome may provide in addition, a substrate for the development of parotid MALT lymphoma (4). Sjögren's syndrome is usually seen in middle-aged women (9 out of 10 patients are women) but may also occurs in all age groups and in children. It is a chronic autoimmune disease that ends in the destruction of the gland, characterized by concurrent keratoconjunctivitis sicca, xerostomia, and rheumatoid arthritis. The benign lymphoepithelial lesions that occur in this syndrome appear as unilateral or bilateral parotid swellings. Enlargement of the parotid gland is seen in approximately 50 percent of patients with Sjögren's syndrome and as pointed out before, patients with Sjögren syndrome have increased risk of developing lymphoma. In summary, we can say that lymphoid proliferations of the salivary glands can be either reactive (lymphoepithelial sialadenitis of Sjögren syndrome) or no-reactive or malignant (NHL-MALT type in 80% of cases derived from lymphoepithelial sialadenitis) (10).
In the thymus, the relationship between lymphofollicular hyperplasia and NHL-MALT-type is uncertain. Parrens et al (11) analyzed 14 cases with a diagnosis of thymic follicular hyperplasia in patients with connective tissue disease (n = 2), myasthenia gravis (n = 11), or both (n = 1). In 11 cases, well-defined reactive lymphoid follicles were surrounded by a continuous layer of medullary epithelial cells, with polyclonal rearrangement of the immunoglobulin heavy chain gene (IgH). In 3 cases, ill-defined lymphoid follicles with sheets of centrocytic-like B cells disrupting the medullary cytokeratin epithelial network were observed on certain sections. These cells expressed the phenotypic features of memory B cells with CD20, CD79a, and Bcl-2 positivity and CD5, CD10, CD23, and Bcl-6 negativity, and a monoclonal rearrangement of the IgH gene.
In the ocular adnexa malignant lymphomas and reactive lymphoid hyperplasia are sometimes difficult to differentiate morphologically and have often been categorized together as a lymphoproliferative disorder. Immunogenotypic characters of these diseases have not yet been well clarified. In one study MALT lymphoma constituted 86% of the primary lymphomas and an autoimmune mechanism may be involved in the lymphomagenesis of ocular adnexal MALT lymphoma (12).
a) Translocations: Translocations play a central role in the pathogenesis of MALT lymphomas, being the most important t(11;18)(q21;q21) present in about 50% of cytogenetically abnormal low grade MALT lymphomas. Other translocations are t(11;14)(q13;q32), t(1;14)(p22;q32) and t(1;2)(p22;p12) being the last two rare but recurrent translocations.
a.1) t(11;18)(q21;q21): This translocation, appearing to be the key genetic lesion in MALT lymphomas (present in about 50% of cases), yields overexpression of a chimeric transcripts encoding structurally distinct API2/MALT1 fusion protein (API2 = APoptosis Inhibitor-2 / MALT-1 = Mucosa Associated Lymphoid Tissue lymphoma Translocation gene-1). API2 gene sequence located in chromosome 11q21 encode Inhibitors of APoptosis (IAPs) known as c-IAP2, HIAP1, and MIHC, while MALT1 alias MLT (MALT Lymphoma-associated Translocation) is in chromosome 18q21 encoding several Ig-like C2-type domains. Pathophysiologically, the increase of API2 encoding IAPs leads to the inhibition of apoptosis yielding long-lived or immortal cells with genetic instability that survive long enough to acquire other DNA damage (e.g.: p53 gene alteration or deletion, overexpression of Bcl-10) ending in a malignant process (13,14,15). In fact, MALT lymphomas with the t(11;18) translocation manifest increased nuclear staining of Bcl-10 in addition to overexpression of MALT1 (16,17).
a.2) t(1;14)(p22;q32) and t(1;2)(p22;p12): The presence of these genetic anomalies mean the translocation of Bcl-10 gene (1p22) to the immunoglobulin heavy chain locus (14q32) or to the immunoglobulin kappa light chain locus (2p12) resulting in deletion of regions of the Bcl-10 gene and/or dysregulation (overexpression) of Bcl-10 protein leading to increase cell proliferation and gene instability (17,18).
Interest has focused on the cytoplasmic regulatory protein Bcl-10, thought to play an important role together with API2/MALT1 chimeric gene in the genesis of extranodal, marginal zone (MALT) lymphomas. Normally, Bcl-10 is expressed only in lymphoid tissues and the breasts. It is expressed in addition, in the malignant counterpart B-cell lymphomas. The presence of Bcl-10 may be demonstrated by immunohistochemistry of formalin-fixed and paraffin-embedded tissues using mouse anti Bcl-10 monoclonal antibodies. In normal B-cell follicles, Bcl-10 protein shows different expression among various B-cell populations of the B-cell follicle, being expressed abundantly in the germinal center, weakly in the mantle zone and moderately in the marginal zone. This fact indicates that Bcl-10 function is essential for normal T and B-cell development (proliferation, maturation and regulation of apoptosis). Irrespective of their stage of B-cell maturation, Bcl-10 is predominantly expressed in the cytoplasm. In T and B lymphocytes Bcl-10 acts as a regulator of lymphocyte proliferation that specifically connects antigen receptor signaling to NF-kB activation and promote apoptosis and suppress malignant transformation in vitro. The NF-kB proteins are normally activated by Bcl-10 after lymphocytes encounter their antigens (e.g.: invading organisms such as bacteria) causing lymphocytes to fully multiply and mature and release antibodies and effector lymphocytes targeted against those specific antigens. Experimentally in mice lacking the Bcl-10 gene, lipopolysaccharide (LPS) or endotoxin failed to stimulate B cell proliferation. Bcl-10 belongs to a family of gene/proteins containing caspase recruitment domains (CARD) involved in regulation of apoptotic pathway accomplishing antioncogene function promoting apoptosis and suppressing malignant transformation in vitro. It has been reported that Bcl-10 and MALT1 cooperate in a final common cascade of events leading to increased activity of the NF-kB signaling pathway (16,17). It is not surprising that the critical NF-kB pathway should be involved in MALT lymphomas, given that this family of transcription factors is activated by both antigenic stimulation and inflammatory cytokines. The contributory factors that currently support the model of MALT lymphoma pathogenesis is given by a milieu of chronic infection, chronic inflammation and lasting oxidative stress providing all a common background for the development of MALT lymphomas leading to chromosomal translocations and mutations (4,10). Interestingly, Chlamydia species share many features with H. pylori, because they too are associated with chronic persistent infection; induce a polyclonal lymphoid infiltrate in extranodal mucosa-associated sites; and have been implicated as cofactors in the development of both carcinoma and lymphoma (18). These common threads may prove to be part of the fabric of MALT lymphoma pathogenesis. MALT lymphomas with t(1;14)(p22;q32) showed strong Bcl-10 expression in both the nucleus and cytoplasm and MALT lymphomas lacking the translocation may exhibit Bcl-10 expression in both the nucleus and cytoplasm although at a much lower level. Follicular and mantle cell lymphomas generally displayed Bcl-10 expression compatible to their normal cell counterparts. In MALT lymphomas the subcellular localization of Bcl-10 is frequently altered in comparison with their normal cell counterparts, suggesting that ectopic Bcl-10 expression may be important in the development of this type of tumor (19). Finally, Bcl-10 has been described associated to colon cancer, germ cell tumor, lymphomas (MALT, follicular), mesothelioma and sezary syndrome.
a.3) t(11;14)(q13;q32): Generates the chimeric gene Bcl-1/IgH in B-cell malignancies. This translocation will be analyzed in the next paragraph cyclin dependent kinases.
b) Cyclin dependent kinases: Physiologically, DNA damage activate checkpoint pathways producing G1 or G2 cell cycle arrest. At G1 the DNA may be repaired or if such repair is not feasible apoptosis is induced, while G2 checkpoint prevents inappropriate mitosis of unrepaired DNA. Cell cycle progression is driven by cyclin-dependent kinases (CDK) in association with specific cyclin proteins. The tumor suppressor p53 re-enforces G2 arrest through the CDK inhibitor p21. Genotoxic stresses stabilize p53 protein allowing it to function as a nuclear transcription factor that induces expression of several target genes including p21, Bax (pro-apoptotic protein) and the inhibitor of p53 Mdm2 (20,21). Mdm2 (Murine double minute 2) protein binds to p53 inactivating and targeting it for destruction by ubiquitinaton. p21 functions as a universal cyclin-dependent kinase inhibitory (CDKI) protein, with affinity for G1 and G2 cyclin-CDK complexes. Most human cancers contain mutations in the cell cycle proteins (oncogenes) that lead to inappropriate stimulation of the cell cycle, and hence uncontrolled cell division. Cyclin-dependent kinases (CDKs) are key regulators of cell cycle progression whose function is frequently deregulated in most human tumors either by increased expression (overexpression) of activating cyclins (e.g.: frequently cyclin D and E); decreases expression of inhibitory peptides (e.g. p16 and p21); or substrate loss (e.g. p53, retinoblastoma gene deletion). Cyclin D1 alias Bcl-1 (B-cell leukemia/lymphoma-1), CCND1 (CyCliN D1) or PRAD1 (parathyroid adenomatosis 1) may be overexpressed in malignancies being detected by monoclonal antibodies in paraffin sections. Bcl-1 controls cell cycle at G1/S transition (restriction point) by the binding to CDK4 and 6 (cyclin D1-CDK4-6 complex inhibited by p15, p16, and p21). The complex cyclin D1-CDK4-6 phosphorilates Rb releasing E2F that induce the synthesis of proteins required by the cell to move from G1 to S going on to the cell division. The Bcl-1 sequence is located in chromosome 11q13. The translocation t(11;14)(q13;q32) generates the chimeric gene Bcl-1/IgH in B-cell malignancies placing Bcl-1 on chromosome 14 near JH (junction genes of IgH). This translocation implies no fusion protein but promoter exchange resulting in that the Ig gene enhancer stimulates the expression of Bcl-1 being this the oncogenic mechanism that results in overexpression of Bcl-1 which accelerates the cell transit through the G1 phase. The expression of cyclin D1 protein (nuclear localization) is cell cycle dependant with maximal expression at the end of G1 keeping high levels until M. t(11;14) is more frequently found in mantle cell lymphoma, B-prolymphocytic leukemia, splenic lymphoma with villous lymphocytes and rarely in chronic lymphocytic leukemia and multiple myeloma. The prognosis vary according to the disease.
c) Adhesion molecules: In general, the expression of adhesion molecules on neoplastic cells imply the attachment of malignant cells to their tissue of origin with low probability of metastasis, the contrary occurs in the absence of such molecules. Expression of adhesion molecules in low-grade B-cell NHL-MALT-type of the gastrointestinal tract has been reported in recent years. Yi-Xuan Liu et al (22) examined the lymphocytic homing receptors 4ß7 integrin, L-selectin, VLA-4 and Mucosal Addressin Cell Adhesion Molecule-1 (MAdCAM-1) in low-grade lymphoma of the gastrointestinal tract and other organs such as the ocular adnexa and thyroid, observing changes in the expression pattern associated with high-grade transformation. Neoplastic cells in gastrointestinal low grade NHL-MALT-type were found to be 4ß7 integrin (+) and L-selectin (+) (keep the aherence to tissue of origin) while in gastrointestinal high-grade lymphoma and diffuse large B-cell lymphoma 4ß7 integrin and L-selectin were negative (-) (high risk of metastasis). Endothelial cells in gastric MALT lymphomas expressed MAdCAM-1. Most cases in the ocular adnexa with low-grade MALT lymphoma were 4ß7 integrin (-), L-selectin (+); and in the thyroid, most cases of both low- and high-grade MALT lymphoma were 4ß7 integrin (-), L-selectin (-). These findings show that 4ß7 integrin and L-selectin may play an important role in the lymphocyte homing of gastrointestinal low-grade MALT lymphoma and in the loss of 4ß7 integrin expression throughout the course of high-grade progression.
Treatment: Currently, stage I malignant lymphoma including intermediate or high grade MALTomas originating in the parotid gland may be successfully treated by surgical procedure directed to remove the tumor (tumorectomy), total parotidectomy and/or local-regional radiotherapy. In stage II radiotherapy plus chemotherapy (CHOP) is the treatment of choice (18). However, at present new ways of treatment are under study, one of these is the use of cyclin dependent kinase inhibitors, that produce cell cycle phase arrest by inhibition of CDK phosphorilation acting as tumor suppressor (23). Other currently assay is the use of Mdm2 inhibitors that may exert an anti-tumor effect restoring normal p53 activity in malignant cells with Mdm2 overexpression (24). On the other hand, Bcl-10 overexpression is associated to colon cancer, germ cell tumor, lymphoma (follicular, MALT), mesothelioma and Sezary syndrome so the development of drugs that block the activity of Bcl-10 (inhibitor of apoptosis and regulator of lymphocyte proliferation) could be in addition an effective treatment.
The parotid gland maltoma developed in our patient was associated with Sjögren syndrome that gave an autoimmune substrate for the development of such malignancy. In addition, she was cyclin D1 negative meaning that there was not overexpression of cyclin D1, being this an important fact in the indolent behavior of NHL-MALT type, making a difference with mantle cell lymphoma and B-prolymphocytic leukemia that have an aggressive behavior. On the contrary, Bcl-2 was positive in our patient signaling that the apoptotic machinery was normally functioning making the malignant cells sensitive to chemotherapy and radiotherapy as it was confirmed by the response to radiotherapy administered. Currently five years later, the patient is in well health condition enough time to be considered cured from NHL-MALT type of the right parotid gland.
As a corollary, we may say that indolent or aggressive characteristic of malignant cells depend on their biological behavior that ultimately rests on the DNA. As greater is the DNA damage affecting different cell functions, the major is the aggressiveness of the malignant cells. This emphasizes the importance of the laboratory work in establishing the different DNA damage characterizing the several kinds of cancers being for this purpose quite useful the DNA microarray technique. This knowledge allow us to establish from the clinical viewpoint, the prognosis and the likelihood of the response to treatment and in addition the development of new more specific and effective drugs to control the malignant diseases.
Citation: Casanova ER. Parotid gland non-Hodgkin lymphoma – MALT type. Clinical Case. Molecular analysis. www.egoncasanova.cl 2005
1. Isaacson P.G. The MALT lymphoma concept updated. Ann Oncol 1995;6:319-320
2. Sarris A.H, Papadimitrakopoulou V, Dimopoulus M.A. Primary parotid lymphoma: The effect of International Prognostic Index on outcome. Leuk Lymphomas 1997;26:49-56
3. Von Stritzky M, Wereldsma JC, Pegels JG. Parotid mass as first symptom of a malignant lymphoma. J Surg Oncol. 1998;67:25-27.
4. Trevor J.I. McGill, Chin-Lee Wu. A 13-year-old girl with a mass in the left parotid gland and regional lymph nodes. New Engl J Med 2002;346:1989-1996
5) Hyjek E, Smith WJ, Isaacson PG. Primary B-cell lymphoma of salivary glands and its relationship to myoepithelial sialadenitis. Hum Pathol 1988;19:766-776.
6) Achuthan R, Bell SM, Leek JP, Roberts P, Horgan K, Markham AF, et al. Novel translocation of the BCL10 gene in a case of mucosa associated lymphoid tissue lymphoma. Genes Chromosomes Cancer 2000;29:347-349
7) Tworek JA, Michael CW. Parotid gland mucosa associated lymphomas and their cytologic mimics. Semin Diagn Pathol. 2001;18:147-150
8) Rubin Ochoa E, Lee Harris N, Zion Pilch B. Marginal Zone B-Cell Lymphoma of the Salivary Gland Arising in Chronic Sclerosing Sialadenitis (Küttner Tumor). Am J Surg Pathol 2001;25:1546-1550
9) Susan L. Abbondanzo, MD. Extranodal marginal-zone B-cell lymphoma of the salivary gland. Ann Diagn Pathol 2001;5: 246-254
10) Harris NL. Lymphoid proliferations of the salivary glands. AM J Clin Pathol 1999;111:94-103
11) Parrens M, Dubus P, Danjoux M, Jougon J, Brousset P, François Velly J, et al. Mucosa-Associated Lymphoid Tissue of the Thymus Hyperplasia vs. Lymphoma. Am J Clin Pathol 2002;117:51-56
12) Mannami T, YoshinoT, Oshima K, Takase S, Kondo E, Ohara N, et al. Clinical, Histopathological, and Immunogenetic Analysis of Ocular Adnexal Lymphoproliferative Disorders: Characterization of MALT Lymphoma and Reactive Lymphoid Hyperplasia. Mod Pathol 2001;14:641-649
13) Stoffel A, Chaurushiya M, Singh B, Levine AJ. Activation of NF-kappaB and inhibition of p53-mediated apoptosis by API2/mucosa-associated lymphoid tissue 1 fusions promote oncogenesis. Proc Natl Acad Sci U S A. 2004;101:9079-9084
14) Dierlamm J, Baens M, Wlodarska I, Stefanova-Ouzounova M, Hernandez J M, Kurt Hossfeld D, et al. The Apoptosis Inhibitor Gene API2 and a Novel 18q Gene, MLT, Are Recurrently Rearranged in the t(11;18)(q21;q21) Associated With Mucosa-Associated Lymphoid Tissue Lymphomas. Blood 1993;11:3601-3609
15) Willis TG, Jadayel DM, Du MQ, Peng H, Perry AR, Abdul-Rauf M, et al. Bcl10 is involved in t(1;14) (p22;q32) of MALT B cell lymphoma and mutated in multiple tumor types. Cell 1999;96:35–45
16) Liu H, Ye H, Dogan A, Ranaldi R, Hamoudi RA, Bearzi I, et al. t(11;18) (q21;q21) is associated with advanced mucosa-associated lymphoid tissue lymphoma that expresses nuclear BCL10. Blood 2001;98:1182–7
17) Lucas PC, Yonezumi M, Inohara N, McAllister-Lucas LM, Abazeed ME, Chen FF, et al. Bcl10 and MALT1, independent targets of chromosomal translocation in malt lymphoma, cooperate in a novel NF-kappa B signaling pathway. J Biol Chem 2001;276:19012–9
19) Ye H, Dogan A, Karran L, Willis TG, Chen L, Wlodarska I, et al. BCL10 expression in normal and neoplastic lymphoid tissue. Nuclear localization in MALT lymphoma. Am J Pathol 2000;157:1147-1154
20) Levine AJ. p53, the cellular gatekeeper for growth and division. Cell 1997, 88: 323-331
21) Agarwal A, Taylor WR, Chernov MV, Chernova OB, Stark GR. The p53 network. J Biol Chem 1998, 273: 1-4
22) Yi-Xuan Liu, Yoshino T, Ohara N, Oka T, Zai-Shun Jin, Hayashi K, et al. Loss of Expression of 4ß7 Integrin and L-selectin Is Associated with High-Grade Progression of Low-Grade MALT Lymphoma. Mod Pathol 2001;14:798-805
23) Go JH. Methylation analysis of cyclin-dependent kinase inhibitor genes in primary gastrointestinal lymphomas. Mod Pathol. 2003;16:752-755
24) Flores C, Sobrevia L. Tumorogénesis y proteína mdm2. Rev. Méd. Chile. 2000;128:539-546


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CARMARTHENSHIRE-L ArchivesArchiver > CARMARTHENSHIRE > 2004-01 > 1073601393
From: Pat Powell <>
Subject: Re: [Cmn-L] 1901 census
Date: Thu, 8 Jan 2004 22:36:33 +0000
In-Reply-To: <000001c3d611$5c6f6c20$5036b5c8@cdrsoftware>
Hello Dilys
If you go back to enum dist 23 and find folio 149 then No19 Wern road is
at schedule 206.
If you are ever wondering about another address in the 1901 census then
you can check if it is there by doing what I did for this address.
It won't cost any money.
If you select address search and then in this case of 19 Wern Road I put
in Wern* and Llanelly.
That gave me all the addresses present in Llanelly that contained the
word Wern - and 19 was included - so then I went and had a look on the
In message <000001c3d611$5c6f6c20$>, dilys karen
rees <> writes
>Three years after buying the 1901 census, I'm finally looking through it for
>my Hopkins family and I've come up against a little difficulty. I decided to
>look up their address from the 1991 census, wern rd.which I found in
>enumeration district 23 but only the right side of the road, ie, the even
>numbers. I need the left side, uneven numbers as I'm looking for number 19.
>I've looked in enu. districts 21,22,24, 25 but haven't found Wern Rd. again.
>Can someone give me a clue how this works?
>Dilys karen Rees - Goiânia, Brazil
>==== CARMARTHENSHIRE Mailing List ====
>Carmarthenshire Place Names Database - Looking for a farm etc you cannot find -
>Contact - - Let him know the name of the Farm House
>etc - He will search the Database
Pat Powell
This thread:
|Re: [Cmn-L] 1901 census by Pat Powell <>


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Persons using assistive technology might not be able to fully access information in this file. For assistance, please send e-mail to: firstname.lastname@example.com. Type 508 Accommodation and the title of the report in the subject line of e-mail.
Surveillance for Cholera -- Cochabamba Department, Bolivia, January-June 1992
Following the epidemic spread of cholera in Peru (1), in April 1991, health officials in neighboring Bolivia established a surveillance system to detect the appearance and monitor the spread of cholera in their country. The first confirmed case in Bolivia was reported on August 26, 1991; by December 31, 1991, a total of 206 cases had been reported, and 21,324 probable and confirmed cases were reported during 1992. This report summarizes cholera surveillance in Cochabamba department (1992 population: 1,070,000) in central Bolivia (Figure 1) for January-June 1992; the assessment was one element of the Data for Decision Making (DDM) Project conducted by the Child and Community Health Project, Bolivia's Ministry of Social Security and Public Health (MSSPH), the U.S. Agency for International Development (USAID), and CDC.
In April 1991, the MSSPH established three categories of case definitions for cholera surveillance: 1) suspected -- acute diarrhea in a person living in an area where Vibrio cholerae O1 had not been reported previously (stool cultures were obtained from patients with suspected cases); 2) probable -- diarrhea with dehydration, vomiting, and leg cramps in a person living in an area with reported cholera cases or related epidemiologically to another person with cholera (stool cultures were not recommended for patients with probable cases); and 3) confirmed -- diarrhea in a person with a stool culture positive for V. cholerae O1. A two-page case-report form was designed for tabulating and investigating each case and was distributed to all health units in the country. In July 1992, the two-page cholera surveillance form was replaced by a quarter-page surveillance form that collected data on fewer variables.
Cases reported during January 1-June 30, 1992, were analyzed. During this period, 4087 cholera cases in residents of Cochabamba department were reported to the MSSPH; surveillance forms were submitted for 2962 (72%) and oral reports for 1125 (28%) cases. Data about the 2962 cases reported on the surveillance form were used to evaluate the form and to characterize the epidemiology of cholera in Cochabamba department. Of the forms received, data on patient's age, sex, address, and outcome were available for 97% of reported cases; however, information on signs and symptoms of illness was reported for approximately 63% of cases.
The 2962 reported cases included 2667 classified as probable and 295 classified as confirmed and represented an incidence of 2.8 per 1000 population in Cochabamba department. Of the 2962 persons, 1527 (52%) were male (Table 1); 2539 (86%) were aged greater than or equal to 15 years, and 157 (5%) were aged less than 5 years. A total of 1621 (55%) cases occurred in residents of urban areas and 1341 (45%) in residents of rural areas. Of 2878 patients for whom hospitalization status was known, 2449 (85%) were hospitalized; hospitalization rates were similar in urban (83%) and rural (87%) areas. Forty-three persons died (overall case-fatality rate {CFR}=1.4%). Thirteen deaths occurred among all urban cases (CFR=0.8% for urban areas), and 30 deaths occurred among 1328 reported rural cases (CFR=2.2% for rural areas).
Reported by: G Pereira, MD, Ministry of Social Security and Public Health, La Paz; Child and Community Health Project, La Paz; J Flores, MD, Chief of Epidemiology, R Agudo, Health Unit, Cochabamba; US Agency for International Development, Bolivia. US Agency for International Development, Washington, DC. Pan American Health Organization, Washington, DC. Data for Decision Making Project, International Br, Div of Field Epidemiology, Epidemiology Program Office; Foodborne and Diarrheal Diseases Br, Div of Bacterial and Mycotic Diseases, National Center for Infectious Diseases; Div of Field Svcs, International Health Program Office, CDC.
Editorial Note
Editorial Note: Features of the cholera epidemic in Bolivia have been similar to those in neighboring countries: the disease has predominantly affected adults in both rural and urban areas (1). The overall CFR for cholera in Latin America has been approximately 1% (2) -- lower than that in other epidemics (3). The CFR has been higher in rural areas of Latin America (as demonstrated in Cochabamba department), reflecting factors such as lack of access to health care, inadequate distribution of oral rehydration salts, and delays in providing prevention and treatment education outside urban areas (4).
The challenges associated with cholera surveillance in Bolivia are similar to those in other Latin American countries that initiated cholera prevention and control programs after the epidemic began in Peru. For example, surveillance systems established to detect and investigate the earliest cases initially were effective; however, as the number of cases increased, available resources for reporting were strained because 1) complex case definitions constrained reporting and interpretation of data; 2) lengthy and detailed surveillance forms that were useful in investigating the earliest cases were subsequently unnecessary and cumbersome (in Cochabamba department, reporting using the two-page form was considered incomplete, inefficient, and was often delayed for cases in rural areas; essential data elements could be listed on the quarter-page form, and since its introduction, all cholera cases reported to the MSSPH have been reported with the form); and 3) laboratories in areas of intense cholera activity were inundated by requests for cultures to confirm suspect cases. CDC and the Pan American Health Organization have recommended measures to simplify cholera surveillance and facilitate rapid dissemination of surveillance information for Latin America and the Caribbean (see box) (5).
Analysis of surveillance information at levels below the national level provides health authorities with more immediate information on local disease activity, allowing appropriate decisions to be made regarding the distribution of treatment supplies and/or support personnel. The evaluation of cholera surveillance in Cochabamba department for January-June 1992 is a component of the DDM Project in Bolivia. The USAID-funded DDM Project, in which Bolivia is one of five countries collaborating with CDC, aims to increase data-based decision making in public health for formulating health policies and for program planning, monitoring, and evaluation. In 1992, the MSSPH requested assistance from USAID/Bolivia and CDC to provide training to 41 national, regional, and district program managers, epidemiologists, and other health officials in applied epidemiology, management, biostatistics, and communication skills. The evaluation of cholera surveillance in Cochabamba department was one of the 41 applied epidemiology projects conducted as part of this training program. The results of the evaluation described in this report have been used to strengthen cholera surveillance efforts and prevention activities in Bolivia.
Disclaimer All MMWR HTML versions of articles are electronic conversions from ASCII text into HTML. This conversion may have resulted in character translation or format errors in the HTML version. Users should not rely on this HTML document, but are referred to the electronic PDF version and/or the original MMWR paper copy for the official text, figures, and tables. An original paper copy of this issue can be obtained from the Superintendent of Documents, U.S. Government Printing Office (GPO), Washington, DC 20402-9371; telephone: (202) 512-1800. Contact GPO for current prices.**Questions or messages regarding errors in formatting should be addressed to firstname.lastname@example.com.
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Anita's Swing Coat by Plymouth Yarn Design Studio
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Anita's Swing Coat
Short-sleeved cardigan with single button at the top.
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Sweet Black Angel
Product Details
This strain is the result of crossing some of most prized plants in history owing to their scarcity. We‰ۡó»ve combined the most Indica of the Sativas with the most Indica of the Indicas, Black Domina, to produce this hybrid that represents a new generation of super fast flowering plants that will soon be setting the standard in growrooms across the world. Ready in just over 7 weeks! With her sweet, musky taste with blueberry overtones, whoever tries this sweet beauty will fall under her spell.
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The rural independents have dared the Coalition to put up or shut up, and stop looking for excuses to walk away from its pledge to try to collapse the government by moving a no-confidence motion in Parliament.
They believe the latest qualification surrounding the Coalition's motion is another excuse to back away from the threat issued by Opposition Leader
The Opposition has now decided not to move the motion unless the independents indicate first whether they would support it – a departure from the original position on March 22, the day after
The tactic was designed to pressure the independents to publicly back the government or otherwise.
"And it will be up to the independent members of Parliament to look into their consciences, to consult with their electorates,'' Mr Abbott said on March 22.
However, the Coalition reneged on the budget week threat and Mr Pyne said he would delay until after it was delivered because the budget would be a disaster and would provide further momentum for the motion to pass.
"After the budget, it will be even more apparent how useless the government is and a no-confidence motion will be even more appropriate,'' Mr Pyne said on May 7.
Pyne 'frightened or embarrassed'
Now, Mr Pyne has written to Mr Windsor, Mr Oakeshott and others saying that should the motion pass, the government would be pushed into caretaker mode and an election would be held as early as August 3.
However, it is understood that should the requisite crossbench support not be forthcoming, the motion will not be put.
Mr Windsor told the AFR Weekend that Mr Pyne was either "frightened or embarrassed'' about the original threat and was looking for an excuse not to proceed.
He believed the Coalition was trying to make the independents responsible by putting the onus on them as to whether it was moved or not.
Thus, he said he and Mr Oakeshott were prepared to test the issue next week. "It would be a worthwhile exercise, as we draw to the conclusion of the Parliament, for MPs to express their views on its performance and I would welcome that debate,'' Mr Windsor said.
Mr Oakeshott challenged the Coalition to put their words into action.
"If Mr Abbott, and Mr Pyne and his colleagues truly believe this to be the worst government in the history of the world. . . I invite them to put their case on the floor of the Parliament,'' he said.
"Grovelling to the crossbench. . . and threatening to do something for week upon week upon week builds the view that this is just the shallow tactic of destabilising and has nothing to do with the substance of the most serious charge they are making.''
The Australian Financial Review


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DORSET appear to be closing in on victory in their final Unicorns Championship match of the season against Cornwall at Dean Park.
Chris Park's team lead their visitors by 158 runs with just the final five wickets to find after a strong second day in this low-scoring contest.
Mark Wolstenholme (5-65) stamped his authority on proceedings with a quick-fire treble to tidy up the tail-end as Cornwall were restricted to 147 in their first innings.
But Dorset's quest to build on their 57-run lead got off to sluggish start as Michael Porter and Ryan Scott fell for single figures with the hosts restricted to 22 for three.
Their tally was boosted by a belligerent performance from Jake Lintott (47) but the hosts were still struggling with deliveries from Neil Ivamy (4-71) and laboured to 110 for seven.
Wolstenholme (25), Sam Thomson (24*) and James Hayman (21) put up a strong fight as Dorset eventually mustered 189, taking the ball with a healthy lead of 246.
Tom Hicks tumbled two wickets with Wolstenholme, Hayman and Lintott all claiming scalps as Cornwall finished the day on a meagre 88 for five.


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Little Elm HS was again the site of the annual District 5-4A track meet. The two-day event was not concluded by press time – see our Facebook or Twitter sites for updates. Competing on day one were hurdler Bailey Uptmore and district champ discus thrower, Tyler Shemberger. Joining him as a regional qualifer: pole vaulters Sarah Hall and Brooke Smith and discus standouts Katy O'Dell and Maddie Parkison. Photos by Mark K. Campbell
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