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The problem is that government does a pretty lousy job of "making sure everybody's got a shot."
Think about it; we spend about $600 billion on public schools, more per pupil than any other country except Switzerland, and the results are consistently disappointing as a whole: "14th out of 34 OECD countries for reading skills, 17th for science and a below-average 25th for mathematics."
The federal government spends about $18 billion per year on "job training" programs, but the GAO has concluded that the data on the effectiveness of job-training programs collecting federal funds is either outdated or nonexistent: "Little is known about the effectiveness of employment and training programs because, since 2004, only five reported conducting an impact study, and about half of all the remaining programs have not had a performance review of any kind." James Bovard laid out the repeated failure of most federally funded job training programs since 1962.
Most of our anti-poverty programs have made no real dent in the problem, despite the fortunes spent on them: "The Census says 46 million Americans remain mired in poverty, and this is greeted as good news, because demographers had been expecting worse. About 15 percent of Americans are poor. That is the same ratio as in 2010 — and slightly higher than in 1966, despite the $16 trillion Washington has spent fighting poverty since Lyndon Johnson declared war on it."


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subset: commoncrawl


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Vintage in the City was last Saturday and was especially fun for me as a Pin Up Model and someone who loves Vintage here in Des Moines. There were fun in store specials, food and fun.
I started the day going to 5 & Diner to get in the mood for it. My boyfriend and I went and had that wonderful diner experience or music, James Dean Paper stand ups, and we even talked Pin UP Pictures with the waitress, ending the event there with her showing me a picture of her from the old days!
Then I went over to Funky Finds Vintage and Retro next to Dorthea's Closet. I had been to some of the other's already as well I had been meaning to go to Funky Finds and showcase this little store.When you go don't forget to go downstairs because I think that is where the magic REALLY happens. I loved everything I saw in there and found lots of items I don't generally see in other vintage stores. You have to go in to see what I mean.
While I was there they had Shirley Temples and Animal Cookies and lots of amazing kewl stuff to look at. I walked away with two cute little aprons for ideas for my Vintage Inspired Apron Line, A Breakfast at Tiffany's Vinyl Album, A Retro Housewife Suburban Wives do it Better Book, and a hug from the owner! What could be better!?
While I was walking around some of the owners from Vintage No. 35 and what is funny is I have been waiting for their new move and planned on going to showcase them in their new shop. I handed off my card and can't wait to hear back from them so I can go take pics and talk them up too!
I still have the card for Vintage in the City and plan on checking out some of these other cool Retro and Vintage stores. I have no clue why Atomic Garage and A-Ok Vintage were not on the list but I want you all to remember those are also great Vintage places to go to.
Here are the other ones on the list in case you missed Vintage in the City as well as my other favorites:
Brass Armadillo Antique Mall
Dorothea's Closet Vintage
The Vintage Clothing Boutique
Found Things
Porch Light
Atomic Garage Valley Junction
A Okay Antiques
American Dream Machines
Vintage Modeling
West End Architectural Salvage
I ended my day changing my Pin Up look a bit and getting Betty Paige Bangs and updating my White Blonde Color over at Aveda Institute Des Moines from my hottest little ruffian Alyxx Peterson. (I'm trying to get her to be a Ruthless Pin Up Girl to showcase the other side of Pin Up here in Des Moines)
Until Next Time … XoXo~TrishaTrixie
Find me at my Model page at Trisha Trixie Model Page
Find more about my Vintage Inspired Fashions at SensaFashion
Trisha Trixie Hunter is a Vintage Inspired Model and Fashionista Fashion Blogger for Fashionista Fun by SensaFashion as well as Fashion Designer for her own line Fashion Femmes Le Boutique bySensaFashion. Follow Trisha on Twitter @TrishaTrixie @SensaFashion or Facebook.


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conaito Technologies Introduces the SIP SDK - A powerful and highly versatile VoIP SDK to accelerate development of SIP applications - Release v3.0
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use the Single License under your Single Service or Product. So, if you have two different Products/Services, then you would have to buy two license keys.
But you are free to use a single license for as many copies of the product/ service for which you have purchased the License Key. The exclusive selling of the conaito VoIP SIP SDK without it being integrated into product/service is not permitted.
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The Support and Maintenance subscription provides you with eMail support for all of our products. In addition your subscription provides all new product releases and updates while your subscription is active.
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You are free to redistribute, as many conaito VoIP SIP SDK incorporated copies of your product or service. conaito Technologies provides royalty free licensing, you don't have to pay any fee or royalty to redistribute your products or services which incorporate conaito VoIP SIP Components. We do not charge any yearly or monthly fee.
Further information can be found in our license agreement or in the download section.


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Choose from Three Options
- $45 for a facial (a $110 value)
- $45 for a 60-minute Swedish, deep-tissue, or shiatsu massage (a $95 value)
- $85 for a facial and a 60-minute Swedish, deep-tissue, or shiatsu massage (a $205 value)
Nani Skin Care
A cast of aestheticians, massage therapists, and beauty professionals work under one roof at Nani Skin Care, where they keep skin glowing with help from products by Bioelements Professional Skin Care. Facials, customized to skin type and condition, incorporate deep cleansing with invigorating massage to restore a vibrant, youthful appearance to dull, aging complexions. Nani Skin care also offers an array of other treatments. For skin below the neck, the aestheticians administer a slew of spa treatments, including exfoliating salt glows and relaxing footbaths.
During 60- and 90-minute massages, aromatherapeutic scents guide muscles into relinquishing any stress or tension. Adults and teens alike can stop in for a Youngblood mineral-makeup lesson or schedule a makeup application to prepare for a wedding day or a night full of dancing and plotting to steal the queen's crown.


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SEVERN Valley Railway (SVR) will play host to modern rail royalty when UK Railtours' Silver King takes to the rails.
Starting its journey in London Marylebone on Saturday, September 6, the 3000 horse powered, air-conditioned train will travel on the Chiltern Line before arriving in Kidderminster.
Once there it will cross on to the SVR and continue through the restored stations at Bewdley, Arley, Highley and Hampton Loade to the end of the line at Bridgnorth.
At Bridgnorth, the train will become available for public use on the return journey to Kidderminster, where visitors will have the opportunity to view the train on the platform.
The Silver King features mark three carriages hauled by a Class 67 diesel electric locomotive, all in silver livery.
At the other end of the train, a matching driving van trailer will be operating in push-pull mode.
Clare Gibbard, marketing and communications manager, said: "The visit of the Silver King is very exciting for the Severn Valley Railway.
"It is unusual to see a modern train on a heritage steam railway, stopping at stations which are over 150 years old.
"SVR passengers on the day will have the opportunity to travel on the Silver King as it will form part of the timetable, so its visit will prove quite an experience for some."
Following the Silver King's visit, the railway will also be playing host to its On The Buses event on Sunday, September 7.
During the day, Bewdley station will be taken over by a display of historic public service vehicles from all parts of the country, including a 1950s double-decker bus, which doubles as a fully-licensed bar.
There will also be sales and information stands, die cast and tinplate toys and the opportunity for visitors to enjoy bus rides around Bewdley town centre.


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|Home > Sport > Article
The reigning Australian road champion finished third overall behind Denmark's Lennie Lange Kristensen of the CSC team, who was equal on time with Astarloza's 17 hours 17 minutes and 45 seconds but declared runner-up on a countback of stage placings.
AG2R veteran Jaan Kirsipuu was out of overall contention but took both intermediate sprints yesterday, denying O'Grady the chance to make up ground on the Estonian's teammate.
Astarloza was full of praise for his team's efforts helping him to his first professional win.
"They did a great job and I really owe it to them," he said. "It's the first time I've ever been the leader in a race."
Despite being helped by several compatriots on rival teams in the two intermediate sprints, O'Grady managed only a third placing on the first sprint to gain one second on Astarloza.
O'Grady was then forced to rely on time bonuses from placing first or second on the stage to have any hope of winning overall.
But he crossed the line fourth as Sydney's Graeme Brown, who had helped lead O'Grady out on the intermediate sprints, claimed the stage win that had narrowly eluded him twice during the 735km tour.
Panaria rider Brown said a deal was done with O'Grady's Credit Agricole team to keep the peloton together for the intermediate sprints and set up an Australian yellow jersey.
"I wasn't originally going to lead him out, we were just going to have my team help his team keep it all together for the sprints," Brown said.
"At the last minute I thought, 'well, I've got good legs, if I can help an Aussie out, I'll help him out'."
The only thing missing from Brown's stage win was the chance to go head to head with Robbie McEwen, who withdrew on Saturday because of a knee injury.
The pair's bitter rivalry reached boiling point last week when Brown was relegated from first on the opening stage following a protest by McEwen, who then beat Brown by less than a centimetre on stage three.
"I wanted to beat him and I thought I could," Brown said.
Australia's Cadel Evans won the King of the Mountain for the German Telekom team while CSC rider Andrea Tafi of
Italy took the sprint jersey.
Uni SA's Gene Bate won the under-23 category and Spanish outfit Once was awarded best team.
The South Australian Government announced it would host the Tour Down Under at least until the end of 2009.
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|Merciless leader ends the dream
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Spring begins on Thursday and Tornado Drill Day
It will be a cold and breezy night, with lows near 30 degrees by early Thursday. Expect a mix of clouds and sun on Thursday, with highs in the 50s.
Spring begins at 12:57pm on Thursday. It will feel like Spring for 2 days. We have highs in the 50s on Thursday and in the 60s on Friday.
This week is also severe weather and flood preparedness week. As part of this week, there will be a statewide tornado drill on Thursday. The drill will happen once in the morning and once in the evening. It is a great opportunity to practice your plan for severe weather at home, work and school. The SkyTrak 13 Weather Team is here to keep you and your family safe, during severe weather. If you are away from home during a severe weather event, you can still stay informed on the go at wthr.com or on the SkyTrak13 Weather App for your smartphone.
After 60s on Friday, we are tracking cooler air for the weekend. There will be a cold front moving through central Indiana later Friday night. A few showers are possible along this front, but the bigger story will be the drop in temperature. Highs will be in the 40s on Saturday and only in the 30s on Sunday. This unusual chill will last through early next week.


text: Meta Battle Subway PokeBase - Pokemon Q&A Login Register All Activity Questions Unanswered Tags Users Ask a Question Rules Chat How do you fix the A and B buttons? 0 votes 139 views This is about pokemon becuase it greatly effects my ability to play it. On my D.S. and even on my new D.S.i the A and B buttons wear out quickly and become softer to push. This is becuase they are the most often pushed buttons especially in b/w where you cannot make L=A. So is there a way to fix them without taking them apart/spending money. maitanence asked Apr 8, 2011 by Speed freak I hate when that happens. My old gamecube controlllers had that happen to them. commented Apr 8, 2011 by trachy Maybe don't bash the buttons so hard? XD Seriously though, I've had my DS for over 5 years and everything still works great. commented Apr 9, 2011 by Pokemaster Me too my old nintendo still is clean shiny and no problem commented Apr 9, 2011 by Pok'e Freak 45 Please log in or register to add a comment. Please log in or register to answer this question. 1 Answer 0 votes As long as you can still play on your dsi it is fine but atleast take better care and I think you will have to spend money answered Apr 9, 2011 by SuperDuperl10 Please log in or register to add a comment. Related questions Does pressing the A and B buttons help increase your chances of catching a Pokémon? What are the shape buttons in the Pokemon summaries and what do they do? is true that if you press the buttons wild pokemon are easiest to catch? What buttons do I press to make the Acro bike jump the stones (Omega Ruby)? What do both buttons do in Team Flares base do? Are there any buttons I can press to give me a better/100% chance to catch a Pokemon? How do I fix a corrupt save file on Crystal? I've got Pokemon Yellow and the save file didn't work. I bought it like a month ago, so how can I fix it? Useful Meta Posts Vote for Sun/Moon moveset questions How to change your username How to add a user avatar Why was my post hidden? The points system Question etiquette Flags vs Downvotes Anime FAQ


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Flames NewsFlames Home > Women's Basketball Home > News
Frazee Named To All-Big South First-Team Roster And All-Academic Team
The five major conference awards were divided between four institutions. Coastal Carolina senior guard Alisha Dill, the fourth-leading scorer in the nation at 22.5 ppg, was honored as the Big South Player of the Year. Kelli Darden, a Radford junior forward/center who leads the conference in blocked shots (2.8 bpg), was tabbed the Defensive Player of the Year. Freshman of the Year laurels went to UNC Asheville guard Kyla Jones, a four-time Big South Freshman of the Week.
High Point, the conference regular season champion, swept the final two honors, as Tooey Loy was named Coach of the Year for the second time in three years and senior guard Leslie Cook took home her second-consecutive Scholar-Athlete of the Year award.
Frazee (Xenia, Ohio) was the lone sophomore among the five members of the all-conference first team. She finished the regular season as the conference leader in both free throw percentage (.782) and three-point field goal percentage (.425). Frazee, the Preseason Big South Player of the Year, ended up second among Big South players in scoring (17.0 ppg), rebounding (8.2 rpg), and defensive rebounding (5.5 rpg). She was also third in offensive rebounding (2.8 rpg) and fifth in field goal percentage (.487).
The Buckeye State native, who tied for the conference lead with 11 double-doubles, became the 10th different Lady Flame to win all-conference first-team laurels in the institution's 16 seasons as a Big South member. Frazee posted seven of the 15 games of at least 20 points and 10 rebounds posted by Big South players this season. She won a quartet of Big South Player of the Week awards during the season, tying her with Dill for the most of any conference player.
A kinesiology major with a 3.865 GPA, Frazee added All-Academic Team status to her previous academic recognition. She was named an ESPN The Magazine Academic All-District first-team selection earlier in the season. Frazee helped the Lady Flames achieve the 14th-highest team GPA (3.338) last season.
Frazee and the Lady Flames will enter the Big South Women's Basketball Championship at the Justice Center as the No. 3 seed. Liberty will open its quest for an 11th-straight conference tournament title Thursday evening at 8 p.m., against No. 6 Charleston Southern.
2007 Big South Conference Women's Basketball Award Winners
First-team All-Conference
Alisha Dill, G, Coastal Carolina
Megan Frazee, G/F, Liberty
Kelli Darden, F/C, Radford
Candyce Sellars, G, High Point
Reba Ross, F, Birmingham-Southern
Second-team All-Conference
Corrie Fertitta, F, Radford
Amanda Elder, F, UNC Asheville
Keena Wicker, F, Charleston Southern
Leslie Cook, G, High Point
Johnette Walker, G, Radford
All-Freshman Team
Kyla Jones, G, UNC Asheville
Marisah Henderson, G, Birmingham-Southern
Lacey Lyons, F, Coastal Carolina
Amanda Stull, G, Coastal Carolina
Devin Rivers, F, Coastal Carolina
Academic All-Conference
Leslie Cook, G, High Point
Reba Ross, F, Birmingham-Southern
Megan Frazee, G/F, Liberty
C.J. Ware, G, Coastal Carolina
Shavon Earp, G, Radford
Ashley Fann, F, Winthrop
Rachel Potts, G, Charleston Southern
Ana Baker, G, UNC Asheville
Player of the Year
Alisha Dill, G, Coastal Carolina
Defensive Player of the Year
Kelli Darden, F/C, Radford
Freshman of the Year
Kyla Jones, G, UNC Asheville
Coach of the Year
Tooey Loy, High Point
Scholar-Athlete of the Year
Leslie Cook, G, High Point


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This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
Most commercial vaccines offered to the aquaculture industry include inactivated antigens (Ag) formulated in oil adjuvants. Safety concerns are related to the use of oil adjuvants in multivalent vaccines for fish, since adverse side effects (e.g., adhesions) can appear. Therefore, there is a request for vaccine formulations for which protection will be maintained or improved, while the risk of side effects is reduced. Here, by using an inactivated salmonid alphavirus (SAV) as the test Ag, the combined use of two Toll-like receptor (TLR) ligand adjuvants, CpG oligonucleotides (ODNs) and poly I:C, as well as a genetic adjuvant consisting of a DNA plasmid vector expressing the viral haemorrhagic septicaemia virus (VHSV) glycoprotein (G) was explored. VHSV-G DNA vaccine was intramuscularly injected in combination with intraperitoneal injection of either SAV Ag alone or combined with the oil adjuvant, Montanide ISA763, or the CpG/polyI:C combo. Adjuvant formulations were evaluated for their ability to boost immune responses and induce protection against SAV in Atlantic salmon, following cohabitation challenge. It was observed that CpG/polyI:C-based formulations generated the highest neutralizing antibody titres (nAbs) before challenge, which endured post challenge. nAb responses for VHSV G-DNA- and oil-adjuvanted formulations were marginal compared to the CpG/poly I:C treatment. Interestingly, heat-inactivated sera showed reduced nAb titres compared to their non-heated counterparts, which suggests a role of complement-mediated neutralization against SAV. Consistently elevated levels of innate antiviral immune genes in the CpG/polyI:C injected groups suggested a role of IFN-mediated responses. Co-delivery of the VHSV-G DNA construct with either CpG/polyI:C or oil-adjuvanted SAV vaccine generated higher CD4 responses in head kidney at 48 h compared to injection of this vector or SAV Ag alone. The results demonstrate that a combination of pattern recognizing receptor (PRR) ligands, such as CpG/polyI:C, increases both adaptive and innate responses and represents a promising adjuvant strategy for enhancing the protection of future viral vaccines.
Viral diseases present a huge problem for the global aquaculture industry, where infectious diseases are estimated to be responsible for a production loss of ten to twenty percent each year [
SAV strains are grouped into six different subtypes (SAV1-6), based on sequencing and phylogenetic analysis [
Most of the commercial finfish vaccines against viruses are, like the above-mentioned SAV vaccine, based on inactivated antigens (Ag) or recombinant subunit proteins formulated in oil emulsions. Oil-based adjuvants are based on creating a depot of Ag, which improves Ag delivery to Ag-presenting cells (APC) or by attracting effector cells to the site of injection. However, side effects due to oil adjuvants have been reported and are expressed both physiologically and morphologically [
The Novirhabdovirus VHSV (viral haemorrhagic septicaemia virus) glycoprotein (G) DNA-vaccine is an intra-muscularly (i.m.) injected vaccine that has been shown to induce early non-specific, as well as long-lasting specific protection against VHSV in trout [
DNA plasmid pcDNA3-vhsG [
The experimental challenge study was performed at ILAB's challenge lab facility at the University of Bergen (Høyteknologisenteret, Bergen, Norway), which fulfil the confinement conditions required for working with GMOs and DNA vaccines. Atlantic salmon, pre-smolt (Fister) with a mean weight of approximately 29 g at time of vaccination were kept in tanks supplied with running fresh water at 11–12 °C and fed with commercial dry feed (Skretting, Stavanger, Norway) based on appetite. The fish were starved for a minimum of 48 h and anaesthetized with metacainum (0.1 mg/mL bath treatment) prior to all handling.
Fish were divided into 7 treatment groups (
Treatments, dose regime, number of fish and schedule for the sampling of organs and blood.
|Total # of fish
|Analysis (# of fish)
|Immune gene expression 12 and 48 hpv
|nsP1 RT-qPCR 3 wpc 1
|Histopathology 5 and 6 wpc 2
|nAb assay
|6 wpv
|3 wpc 1
|6wpc 2
|74 + 1
|8 + 8
|15 + 15
|64 + 1
|8 + 8
|15 + 15
|74 + 1
|8 + 8
|15 + 15
|68 + 1
|10 + 10
|15 + 15
|68 + 1
|10 + 10
|15 + 15
|68 + 1
|10 + 10
|15 + 15
|68 + 1
|10 + 10
|15 + 15
The treatment that is underlined,
Spleen and head kidney (HK) were harvested from 8 fish per group at 12 and 48 h post vaccination (hpv) and were stored according to the manufacturer's guidelines on RNAlater (Ambion, Applied Biosystems, Foster City, CA, USA). RNA isolation, cDNA synthesis and RT-qPCR were executed as described previously [
Serum samples from 8 to 15 individuals per group and time point (see
To measure SAV levels during the viraemic phase, a quantitative real-time RT-PCR (RT-qPCR) was performed on viral RNA extracted from sera 3 wpc from 10 individuals per group, as described previously [
A sample was considered infected when it had a relative value between 1.0 × 100 and the cut off value of 3.0 × 10−7 (
Heart samples for detecting SAV-induced lesions were collected from 15 fish/group at 5 and 6 weeks post-challenge and immediately fixed in 3.5% formaldehyde in buffered saline at pH 7.0 (4.0 g NaH2PO4·2H2O, 6.5 g Na2HPO4·2H2O, 100 mL 35% formaldehyde and 900 mL dH2O). To evaluate the severity of SAV-induced heart lesions, a previously defined scoring system was used (no lesion: 0; minimal: 1; mild: 2; moderate: 3; severe: 4), where scores of 2 and more are defined to be specifically induced by an SAV infection [
All analyses were done in GraphPad Prism 5.0 if not mentioned otherwise. Differences in protection (SAV nsP1 RT-qPCR and histology) were statistically evaluated by the Kruskal-Wallis rank sum test with
Primers and probe sequences for quantitative reverse-transcriptase PCR and PCR efficiency.
|Fw/Rev 200 nM
|SYBR® Green
|Fw/Rev 450 nM
|Fw/Rev 900 nM
|Forward *
|2.09/2.16 *
|SYBR Green 3.75 µM
|Fw/Rev 900 nM
|Fw/Rev 200 nM
|Fw/Rev 900 nM
|Fw/Rev 200 nM
|Fw/Rev 900 nM
|Fw/Rev 900 nM
|Fw/Rev 900 nM
Fw; forward. Rev; reverse. * The same primers were used for SYBR Green as for TaqMan.
Transcription levels of selected antiviral innate genes, as well as selected B- and T-cell markers were analysed at 12 and 48 hpv in HK (
Relative expression of (
Relative expression of (
Results showed that IFNa1, IFNγ and two antiviral proteins induced by IFNs (Mx and Vig-1) were strongly induced by the CpG/polyI:C-adjuvanted treatments, which confirms earlier findings [
PAX5, soluble (s) and membrane-bound (m) IgM were chosen as B-cell markers. PAX5 belongs to the family of paired box transcription factors and is present during early B-cell development, but must be repressed for plasma cell differentiation to take place [
Co-receptors for T-helper cells (CD4) and cytotoxic T-cells (CD8) were used as T-cell markers to further study early adaptive responses. Atlantic salmon contain two shorter CD4 domain molecules (CD4-2a and -2b) in addition to the four classical (CD4-1) domains [
The presence of anti-SAV neutralizing responses in sera was measured at 6 wpv and at three and 6 wpc by a viral neutralization assay. It is well known that heat sensitive factors in serum may augment the neutralizing activity of Ab [
Six weeks after vaccination, all fish were challenged by cohabitation with an SAV Subtype 3 isolate, and vaccine-induced protection was measured at three, five and 6 wpc (
Vaccine-induced anti-SAV neutralizing titres from not heat inactivated (
Heart tissue was sampled at five and 6 wpc to evaluate the severity of SAV-induced heart lesions by histological scoring. Protection based on the reduction of the severity of SAV-induced heart lesions was comparable to the protection shown through the reduction of the prevalence of viremia at 3 wpc for all treatments. Here, only histology data for 6 wpc are presented (
Protection against pancreas disease (PD) in vaccinated and control groups based on (
How innate and adaptive immunity interact upon vaccination affects the outcome of protection. Especially, TLRs, included in the PRR-family, have emerged as key components of the innate immune system, activating signals critically involved in the initiation and maintenance of adaptive responses. Thus, TLR stimuli can be exploited as powerful adjuvants to elicit both primary and anamnestic immune responses. In light of this, our group used a combination of a selected CpG ODN [
Here, to follow up and to extend this model, the CpG/poly I:C combo was i.p. injected alone or combined with an i.m. injection of the VHSV G DNA genetic adjuvant. Montanide ISA763A was included as a control adjuvant, i.p. injected in combination with the genetic adjuvant. This was to determine if any enhanced protective responses were induced, since oil-adjuvanted formulations previously had provided a lower protection, most likely due to depot effects [
Correlating to earlier reports, the present CpG/polyI:C formulation induced a distinctively higher upregulation of early innate antiviral transcripts (IFNa1, Vig-1 and Mx) and also higher titres of nAbs compared to all other treatments [
In higher vertebrates, B-cells activated via PRRs and/or by Ag cross-linking of the B-cell receptor rapidly respond, proliferate and differentiate into IgM secreting short-lived plasma cells (SLPC). T-cell help is needed to induce long-term B-cell memory, represented by memory B-cells or long-lived plasma-cells (LLPC) [
Moreover, Desvignes
B- and T-cell markers were, in general, not, or very modestly, induced for all formulations tested, which could be due to the early sampling time points. The results show that fish treated with SAV Ag CpG/polyI:C had a slight, but notable, increase of PAX5 transcripts levels at 12 hpv in both HK and spleen. In spleen, PAX5 induction occurred in parallel to that of mIgM at 12 hpv, while at 48 hpv, PAX5 expression was reduced and mIgM remained stable. This indicates that an early B-cell development takes place [
The immunological mechanisms behind the full protection provided by SAV Ag alone have been reasoned to depend on a T-cell independent (TI) nAb response, as that formulation did not induced an antiviral immune gene response at 5 dpv [
To our knowledge, very few studies have been performed on teleost to investigate the immunostimulatory and protective effects of an i.p. vaccine injected simultaneously with a DNA-based adjuvant injected i.m. The efficacy of the DNA vaccines based on the glycoprotein G from VHSV and IHNV are well-documented; these vaccines have been shown to induce a long-lasting protection against these viruses [
In regards to humoral immunity, diverse responses were seen in the different groups i.m. injected with vhsG. While the SAV Ag oil vhsG treatment showed reduced nAbs titres compared to SAV Ag oil, the water-based SAV Ag formulation co-injected with vhsG had higher titres than SAV Ag alone at both 6 wpv and 6 wpc. Finally, a reduction in neutralizing responses was present when vhsG was co-injected with the SAV Ag CpG/polyI:C formulation, and the NHI nAbTs were reduced by half or more at all three time points compared to SAV Ag CpG/polyI:C. These data show that vhsG induced a slightly higher production of nAbs for the SAV Ag-treated fish co-injected with vhsG, and it also suggests the presence of factor(s) that cause a reduction in humoral responses when CpG/polyI:C-adjuvanted SAV Ag is co-injected with vhsG. For both mammals and teleosts, it has been shown that polyvalent vaccination often negatively affects the generation of specific Ab [
To summarize, the vaccine based on a suboptimal dose of inactivated SAV whole virus Ag formulated with CpG/polyI:C induced the highest nAb responses, followed by the combined treatment of SAV Ag vhsG and, finally, the oil-adjuvanted SAV Ag formulation. The expression of several innate antiviral immune genes showed consistently elevated levels in the groups injected with CpG/polyI:C compared to the other adjuvants tested. B- and T-cell markers were, in general, not, or very modestly, induced for all formulations tested. For groups receiving the vhsG DNA vaccine, no antiviral immune gene expression was detected at these early time points, but as indicated by Martinez-Alonso
Overall, these data show that CpG/polyI:C is a potent TLR-ligand combo, which could be used in future salmonid vaccination strategies against SAV. Further work should be aimed at investigating the duration of the efficacy of these TLR-ligands as adjuvants, while at the same time facilitating their administration. One potential strategy may be to protect the TLR-ligand/Ag formulation from degradation by encapsulating them in protective vehicles, such as nanoparticles, as recently described in [
The authors would like to thank Niels Lorenzen at the National Veterinary Laboratory (Danish Technical University, Copenhagen, Denmark) for providing the VHSV-G DNA plasmid construct and Barbara Spasowska and Glenn Sundnes at MSD Animal Health Innovation AS for their excellent work with the organization of all fish samples.
HLT carried out all of the experiments for this study except the nsP1qPCR, participated in the data-analyses and drafted the manuscript. SV participated in the design of this study, nsP1qPCR, data-analyses and revision of the manuscript. MMcL carried out the histopathology analyses, KEC contributed to the virus neutralization assay. SG provided some of the qPCR assays. PF participated in the design and revision of the manuscript. JBJ participated in the design, interpretation of the data and revision of the manuscript.
The authors declare no conflict of interest.


text:
Name Index
Geographic Index
Subject Index
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Vixman, Rachel
Interview Date
October 20, 1977
Rachel Vixman, a certified parliamentarian and authority on parliamentary procedure, she founded the Pittsburgh Chapter of Hadassah, served as national vice president of the organization in the United States and as associate director of the Canadian Chapter of Hadassah; birth year, 1887;
[T1S1] parents' emigration from Vilna; number and names of siblings in her family; parents' dairy farm in Connellsville, PA; information about her family name; recollections of life in Connellsville; education, Bellefield Elementary School; her employment as assistant librarian at the Carnegie Library in the Oakland section of Pittsburgh; religious education in the home; marriage in 1914; her family's residence in Oakland; attending Zionist meetings at the Zionist Institution in the Hill District; family residence in the Hill District; selling subscriptions to the Jewish Criterion; becomes assistant to Charles Cooper, president of United Hebrew Relief Association (UHRA) of the Irene Kaufmann Settlement;
[T1S2] member, Daughters of Zion; her work as Charles Cooper's assistant for the UHRA; speaking for the Young Men's and Women's Hebrew Association (YMandWHA); her brother's role in founding the YMandWHA Chapter on Fifth Avenue; her courtship and marriage to Herman Vixman; husband's background information; discussion of meetings at the Zionist Institute; birth of children; her children's lives and families; her role in founding the Pittsburgh Chapter of Hadassah; some history of Hadassah in Pittsburgh; her writings for the Jewish Indicator; 1929, moves to New York; her service as National vice president of Hadassah;
[T2S3] attending the World Zionist Organization's meeting in Switzerland in 1929; her family's travels in Europe during this time; the riots in Jerusalem while they were visiting there; discussion of her role in the Zionist conference of 1921; problems with the conference; her service as a certified parliamentarian; her correspondence course in parliamentary law; her contribution to the publication of a new edition of Robert's Rules of Order in 1967; her service as parliamentarian for the National Federation of Women's Clubs;
[T2S4] further discussion of the Guide and Commentary she published for the new edition of Robert's Rules of Order; her residence in Canada for ten years; taking a tour of Israel with the executive director of Canada's Hadassah, Mrs. Adler, in 1958; becomes associate director of Canadian Hadassah; her activities with the women's movement in the Jewish Congress; her involvement with the American League of Peace and Democracy; her service as president of Women's Division of New York University Jewish Cultural Fund; her work with B'nai B'rith Hillel Foundation; becomes national executive director of Young Judea, 1931-36; her writings for the Anglo Jewish Press;
[T3S5] recipient, Woman of the Year Award in 1957 by the Queens County Council Ladies Auxiliary of Jewish War Veterans of the United States of America; the Rachel Vixman Scholarship at New York University; her service as president of Beth Shalom Synagogue in Pittsburgh; her relationship with other organizations in Pittsburgh; her children's educations; her philosophy of service.
Connellsville (Pa.); Hadassah, the Women's Zionist Organization of America; Hill District (Pittsburgh, Pa.); Robert's rules of order; City and town life; Jews--Social life and customs; Zionism
Birth Date
Occupation (father)
Dairy Farmer
Length (hours)
Selavan, Ida
Collateral Materials
Box 107 FF 9
National Council of Jewish Women (NCJW), Pittsburgh Section Papers, 1894-2003, AIS.1964.40, Archives Service Center, University of Pittsburgh
All rights reserved. University of Pittsburgh
Ordering Interview Copies


text:
Music in the SF street sceneEdit
When we first see the crew walk the street of SF, we hear contemporary 80s pop music, but I am unable to find the title & artist anywhere on Memory Alpha. What was it? Thanks. --K. Shinohara 23:40, 4 February 2008 (UTC)
To quote Odo when stuck in a Cardassian turbolift: Well??? --K. Shinohara 14:22, 6 February 2008 (UTC)
- Did you check the credits, or email the composer? --Alan del Beccio 21:45, 6 February 2008 (UTC)
- Or check Star Trek IV: The Voyage Home (soundtrack) (where this question actually belongs, since this has nothing to do with the year "1986" in canon, it isn't like Admiral Kirk could hear the music). Based on that article, I'd guess that it is one of the arrangements by the Yellowjackets. --OuroborosCobra talk 04:03, 7 February 2008 (UTC)
Reused material? Edit
According to Wikipedia (uncited), Rosenman reused elements from his score for Ralph Bakshi's animated Lord of the Rings. I can hear the similarities, but does anyone know of a source for this? —Josiah Rowe 03:48, 22 February 2009 (UTC)


text:
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text:
The above may be illustrated by considering the equilibrium between rhombic and monoclinic sulphur.
monoclinic crystals common, usually of simple forms, as shown by Figure 75i.
Below this temperature the octahedral, above it the monoclinic, is the stable form.
Sulphur exists in two well-known crystalline forms—rhombic, or octahedral, and monoclinic, or prismatic sulphur.
Pyroxenes crystallizing in the monoclinic system are the most important.
At any point outside this area, monoclinic sulphur can exist only in a metastable condition.
A hydrous silicate of magnesia never in distinct crystals as such, but shown to be monoclinic under the microscope.
The monoclinic crystals are prismatic in habit, with deeply striated prism and dome faces.
The crystals are monoclinic and occur in porphyry almost exclusively.
Occasionally, though but rarely, malachite occurs in small dark-green prismatic crystals of the monoclinic system.
Relating to a crystal having three axes of different lengths. Two of the axes are at oblique angles to each other, and the third axis is perpendicular to the plane that is made by the other two. The mineral gypsum has monoclinic crystals. See illustration at crystal.


text:
- OSI-Approved Open Source (16)
- Public Domain (2)
- Other License (1)
- Grouping and Descriptive Categories (15)
- Linux (15)
- Windows (13)
- Mac (12)
- Modern (5)
Top Apps
- Audio & Video
- Business & Enterprise
- Communications
- Development
- Home & Education
- Games
- Graphics
- Science & Engineering
- Security & Utilities
- System Administration
Open Source Teleprompter181 weekly downloads
Portable Celtx
Portable Celtx is a free, open source software tool for writing and formatting a screenplay to meet the exacting screenplay submission standards set by the theater and film industries.43 weekly downloads
SISC is an extensible Java based interpreter of the algorithmic language Scheme. SISC uses modern interpretation techniques, and handily outperforms all existing Java interpreters (often by more than an order of magnitude).12 weekly downloads
Snagit's image and video capture is powerful, but not complex. All-in-One Capture® grabs your entire desktop, a region, a window, or a scrolling window from any webpage or application—-all with a single hotkey or click. Snagit gives you a simple way to edit. Show a complex process, give detailed feedback, or share important information with the people who need it most. Download your free trial now!Advertisement
Caudium WebServer is a single process multi-threaded webserver. It has a built-in pre-processing language and includes an easy to use web-based configuration interface.11 weekly downloads
The B2B eCommerce Project
This is a working Java Server Pages based Shopping Cart. This project is currently a fully functional JSP eCommerce Application (To be used with Tomcat). I'm currently working on JSPCART to become a B2B eCommerce Software.3 weekly downloads
Annotea Ubimarks
Annotea Ubimarks is an application of Annotea shared bookmarks in Mozilla. It helps users to easily organize Web information by using familiar concepts, share findings with trusted peer groups and benefit from the underlying Semantic Web technologies.
Multiverse Open Source World
The Multiverse Open Source World (OSW) is an organized community effort to develop a working virtual world based on the Multiverse platform built by the Multiverse dev community, for training/educational purposes and general benefit of the community.
Open Source Warehouse Management System
The goal of this project is to provide a high-end, open source warehouse management system: picoWMS. This system does not just track inventory, recieve goods, process orders, creates pick tickets but Manages the warehouse.
Share Management
This software integrate a Cifs Shares with a Microsof Windows Server Domain. The software is intentended to be used by system administrators who have to manage users permissions on cifs shares with an automount script at users logon.
The Last Tutorial Management System
This is going to be a easy to use Tutorial Management System, that will be released on an open source terms. It will feature an administrator interface, a moderator interface, and a user submission page much of the ALPHA release is completed.
VISL Constraint Grammar Compiler
The VISL Constraint Grammar Compiler is a natural language parser generator. It is an implementation of Pasi Tapanainen's CG-2 constraint grammar formalism.
VISL Phrase Structure Grammar Compiler
The VISL Phrase Structure Grammar Compiler is an implementation of a parser generator for ambiguous context-free grammars, ambiguous input, and ambiguous output.
gtk-minimo is web/wap browser base on mozilla engine, it is much more stable and faster than the official one.
What if there was an interface like iTunes that was tailored to everything related to the Asian board game go (wei qi, baduk)? In one interface, one could obtain RSS feeds of go news, access go servers, and communicate with other players.
wjue Xoops Collection
A business oriented collection of modules for Xoops CMS, it aims at providing a complet set of coherent CRM apps. under Xoops. Currently it consists of a WebMail (sqMail), a Help Desk (zenTrackXoops), a Marketing and Sales automation (under development)


text:
Case in point: Twitter signed onto an amicus brief in support of overturning the Defense of Marriage Act (DOMA) and "promotes the Planned Parenthood Action Fund as a success story for its promoted tweets program."
Or Macy's, which like Twitter earned one of the lowest grades (1) because of its support for liberal causes – the iconic department store directly supports Planned Parenthood and the gay rights group, Human Rights Campaign.
"We're trying to inform people and help them make wise decisions with their money," Chris Walker, executive director of 2nd Vote told CNSNews.com.
According to its website, "2nd Vote is a group of conservatives who are dedicated to helping you be informed about the everyday choices you make. We believe you can make a difference, and with 2nd Vote you will.
Walker said the app and its database were put together by conservatives, many of whom worked as researchers for political campaigns, to show people what their purchase could help fund.
"Whether you're buying a cup of coffee or whether your buying a hamburger or an airline ticket were letting you what the companies are doing with the money that your spending with them," Walker said.
2nd Vote "grades" companies from 5 to 1, with 5 being businesses that support directly or indirectly the most conservative causes and organizations, and 1 being businesses that support liberal causes.
Businesses are also graded based on equal support for both conservative and liberal causes and groups that support neither. Businesses are graded in four areas – pro-life, the environment, 2nd Amendment rights and marriage.
Walker said conservatives can make an impact by rejecting goods and services from businesses that finance directly or indirectly groups they disagree with.
He cited the recent case of SunTrust Banks' announcement that the Atlanta-based banking institution was severing its ties with the Benham Brothers Real Estate Group because of their support for pro-life causes and traditional marriage.
"Within 12 hours, they changed their position" and reinstated their relationship with David and Jason Benham, Walker said.
"Time and again we're seeing that if conservatives stand up and actually hold their dollars accountable and say my 2nd Vote has a voice, companies will listen, because they want your business more than anything," Walker said. "We like to say, 'Green beats red and blue every time.'"
Some of the other companies graded include Ben & Jerry's (1), Google (1.3), General Motors (1.3), Facebook (2.5), Knights of Columbus (4.4), Chick-fil-A (4.3) and Bass Pro Shop (3.5).
The app is free, but visitors to the 2nd Vote website are asked to provide their email address to access the scoreboard.


text:
KCRW Presents:
Hanni El Khatib
Bass Drum Of Death, Beach Party
The Glass House
200 W. Second St
Pomona, CA, 91766
This event is all ages
Hanni El Khatib Hanni grew up in San Franscisco, California. The son of Palestinian and Filipino immigrants and the first American in his family, he became obsessed with classic Americana and pop culture of the 1950s and 60s. Influenced by pioneers of early rock and r&b (Johnny Burnette, Sam Cooke, Johnny Cash), El Khatib created a musical aesthetic to match his vision. The multi-instrumentalist serves as singer, songwriter & producer for his one-man band (live he is joined by a drummer) that is part blues, part garage rock, part soul, part folk & part doo whop.
As the creative director for HUF and lifelong skater, El Khatib professes to a love for well-crafted objects: classsic cars, cans pomade and stiletto switchblades. This craftsmanship carries over into his music, where El Khatib is inspired and informed by the specificity of a guitar tone or the fuzziness of an amp sound . His background in DIY and skate culture manifests as a desire to "keep mistakes in" and make things "as raw as possible." Merging primitive rock sounds with punk aesthetics, El Khatib toes lines between all genres and ends up firmly in his own.
His diverse interests in music, zines, art, photography, and film, converge around his singular personal aesthetic, which reveals itself in all of El Khatib's work. Combining the old weird America with the brave new frontier of home recording, El Khatib bridges the past and the present to create music that already sounds timeless and were written for anyone who's ever been shot or hit by a train.
BDOD is lead by John Barrett, tied deep into Mississippi's Cat's Purring Collective, who've fostered releases from Dead Gaze and Dent May to mention a few. Pretty much anything awesome happening in and around the Mississippi garage base is happening within contact of those cats.
Beach Party is the intoxicating bi product of creative brain children, Rob Banks and James Hurst. Formed in late 2012, the duo began recording their first demo, collaborating their musical influences and original ideas to put a whole new spin on hedonistic surf rock with a 60's garage band prerogative. After bringing friend's and fellow musicians, bassist Adam Arcos and drummer Nico Macciocca on board, the stylish brood of libertines was complete, giving life to Beach Party and their distinctive sound. The band quickly gained momentum on both SoCal's Coast and the UKs dive scenes through their dynamic sound and spirited performances. With tracks like "Fun", describing a day of hazy misbehavior entrancing the crowd with lines like "Come on, come on, and let's have some fun!", to The Strokes channeling, swoon worthy, love song that is "Brigitte Bardot", it is no wonder Beach Party has quickly become one of HELL-A's most substantial new bands, having supported established acts such as The Warlocks, Best Coast, and the Black Lips while still in their infancy.
Upcoming Events
The Glass House
Sat, July 29
Saved by the 90's
Sat, August 5
Viva! Pomona, Cuco
Sun, August 6
Viva! Pomona, The Coathangers
Sat, September 2
Sun, September 3
DIY Music Festival 2017


text:
capital noun (CITY)
A2 [ C ] a city that is the centre of government of a country or smaller political area:
› [ C ] the most important place for a particular business or activity:
More examples
- In defiance of the ceasefire, rebel troops are again firing on the capital.
- Fighting around the capital has intensified in the last few hours.
- More people live in the capital than in the whole of the rest of the country.
- There is strong support here for the tough economic reforms ordained in the federal capital, Prague.
Thesaurus: synonyms and related words
Towns & regions: towns, cities & villages (general)
You can also find related words, phrases, and synonyms in the topics:
capital noun (LETTER)
A2 [ C ] also capital letter a letter of the alphabet in the form and larger size that is used at the beginning of sentences and names:
More examples
- Names always start with capitals.
- If you write your emails in capitals, it looks as though you are shouting.
- The company's trademark is written in capitals.
- If the text is in capitals, it is difficult to read.
- For some reason, she always writes in capitals.
- It's considered rude to use capital letters in an email because it looks like YOU ARE SHOUTING.
- The poet e. e. cummings wrote his name with small letters, not capital letters.
- Don't forget to put a capital letter on a proper name, like the name of a place or person.
- Every sentence should begin with a capital letter.
- Romantic, written with a capital letter, refers to a specific movement in art and literature.
Thesaurus: synonyms and related words
capital noun (MONEY)
› [ U ] money and possessions, especially a large amount of money used for producing more wealth or for starting a new business:
More examples
- The central bank has announced controls on capital outflows.
- I want to start my own business if I can raise the capital.
- We're only a small business and don't have the capital to compete with the big boys.
- They'll need to raise £1 million in venture capital if they're to get the business off the ground.
- She leaves her capital untouched in the bank and lives off the interest.
Thesaurus: synonyms and related words
You can also find related words, phrases, and synonyms in the topics:
capital noun (COLUMN)
capital adjective (LETTER)
Thesaurus: synonyms and related words
capital adjective (DEATH)
Thesaurus: synonyms and related words
capital adjective (EXCELLENT)
Thesaurus: synonyms and related words


text:
Fujitsu Siemens has been busy rolling out new tech recently and they unveiled their new ultra-high definition equipped laptop at CeBIT 2005. The Amilio M4438 is a behemoth sporting a 17" widescreen (16:10) display with 256 MB of video RAM that displays a pixel resolution beyond current HDTVs. The video is driven by the NVidia GeForce 6800 which should make the Amilio a gamer's dream machine.
The Amilio is available with Pentium Ms ranging from 1.6 GHz through 2.13 GHz and will handle up to 2 GB of DDR2 RAM. This notebook is hot if you want a true desktop replacement. You can put two hard disks in this baby up to 160 GB each for massive storage and do that with RAID 0 and 1 suppport. Throw in the dual layer DVD burner and you can create DVDs with up to 8.5 GB. Oh, I almost forgot the integrated subwoofer. Don't know how much this is going to cost but if you have to ask….
(via infoSync World)


text:
Topic: Supply Chain Dashboard. An example of using dashboards to assist with the complexities of a logistics system.
Dashboard Spy post: 8 Step Approach to Developing BI Dashboards. The CTO of a healthcare company shares his 8 step dashboard methodology in the Computerworld article Developing Clinical Dashboards.
Hospitals, medical centers and other health systems are increasingly using digital dashboard technology to provide relevant, up-to-the-minute information to clinicians in a visually rich format to improve the quality of patient care.
Designing and using clinical dashboards requires substantial physician involvement and a well-defined process. The University of Pennsylvania Health System, a.k.a. Penn Medicine, is currently in the midst of developing the Penn Data Store, a data warehouse and series of individual dashboards, to serve our clinicians and researchers. The Penn story may be of use to you and your organization as you move forward in the world of dashboards.
So starts the article that details how an organization used Oracle's Business Intelligence Suite to create a single data storehouse with all of their patient, admin, financial and supply chain data.
Here are the 8 steps:
- Meet with users to determine data needs
- Design the presentation layer
- Design the semantic layer
- Design the physical layer
- Develop and test all 3 layers
- Perform QA
- Conduct a Pilot
- Begin general rollout
Here are some particulars. See the article for the full story.
1. Meet with users to determine major data needs
Many users and potential users of dashboards aren't familiar with the systems' power and capabilities. They typically use noninteractive spreadsheets and graphs that present data in fixed rows and columns and lack the flexibility of Web-based tools.
The first step in this phase was to inform clinicians of the many additional possibilities that a more powerful tool offers. We did this by first building sample dashboards to demonstrate the tool's capabilities. We then asked the clinicians to identify several key measures, dimensions and filtering criteria for the dashboards they were interested in.
2. Design the presentation layer
For dashboards to deliver the most benefit, users must agree on presentation standards before the design phase begins. It's crucial to achieve agreement on items such as color schemes, graphical objects and navigation standards so future dashboards will look, feel and behave consistently. This will improve user satisfaction and reduce training demands for each new dashboard.
Designers must think carefully about the hierarchy of the data they want depicted in the dashboards and what levels of the hierarchy will be visible. In our example, the hierarchy is Practice Physician Patient. Depending on a user's security status, he may or may not be able to see the patient data.
Once the hierarchy and associated measures such as year, month and practice name were grouped into a dashboard page, we selected the graphical elements. We chose histograms, line graphs, pie charts and simple tables to present the data in an intuitive fashion that met users' needs and simplified navigation through the dashboard pages.
3. Design the semantic layer
The semantic layer maps the presentation layer to the physical layer. Developers prove their worth in the design of this layer. Defining patient populations by disease categories, grouping drugs hierarchically by therapeutic area and organizing physical locations are examples of the challenges that the semantic layer's designer faces. Users play a key role in formulating those definitions. In-depth knowledge of both the presentation layer design and the physical data models is essential.
4. Design the physical layer
As mentioned, try not to change the design of the physical layer. Whenever possible, avoid creating an entire new physical data structure, because doing so generates the need for additional extract, transform and load (ETL) steps each time the clinical data warehouse is updated. Redundantly storing data produces additional storage, backup and maintenance costs and opens up the risk that duplicate copies of data won't be updated with the same frequency as the original.
5. Develop and test all three layers
Users who are new to the dashboard development process will likely need to see how the systems operate with real data. We have found it useful to introduce clinicians to a working prototype to gain early feedback on the design. Regular weekly demo and review sessions then help developers refine and test the design. When you're engaged in this phase of the project, take care to manage scope creep, since participants might be tempted to request new capabilities or data that weren't in the original design. Put off responding to such requests until a subsequent release of the dashboard.
6. Perform quality assurance
Here are several quality-assurance requirements we developed at Penn Medicine:
- Use data from the actual data warehouse, rather than simulated or test data.
- Include monthly and quarterly data warehouse updates during the QA process, especially when the data being used in dashboards will cross calendar months, quarters and years. A year-end data update would be ideal, but most projects can't wait that long.
- Compare dashboard data to the original source systems, to ensure that no translation or presentation errors were introduced during development.
- Test system performance and response times with large amounts of data to ensure that the dashboard responds effectively to users' needs.
7. Conduct pilot tests
Before making a dashboard available, we ask a small group of users to pilot-test it for a few weeks, as a short extension of the QA phase. This provides additional information on usability, performance and quality. If the pilot group recommends moving forward, we proceed to the general rollout. If the pilot group identifies problems, the development team resolves them.
8. Begin general rollout
This phase involves these major components:
- User orientation: New users may need a brief training session. Those who have used dashboards in the past should be able to use the new dashboard with no assistance — if the presentation layer was designed well.
- Support documentation: Gather design and operational specifications and post them on support sites.
- Help-desk hand-off: Write scripts and give them to the help desk for guidance in responding to support calls.


text:
People to Watch in 2012
maria orozova
President and Creative Director, The MOD Studio
Maria Orozova heads the award-winning agency, The MOD Studio. With over ten years developing successful advertising and branding campaigns for local and national clients, her integrated marketing know-how fuels the MOD Studio's creative print, web, and editorial designs. Her work has earned numeorus ADDY awards and GDUSA American Graphic Design Awards. Orozova is also a featured writer for elite publications such as Entrepreneur Magazine and Texas CEO Magazine, and serves on the board of the Austin Advertising Federation. She is committed to giving back to the community by supporting the Center for Child Protection, Lifeworks, Habitat for Humanity and Austin Sunshine Camps. In addition to her professional and volunteer duties, Orozova also finds time to pursue a wide range of personal interests, including pilates, traveling and interior design. As for her agency, The MOD Studio philosophy is simple: be smart, strategic and creative.
Where were you born or grew up, where do you live, does this effect your design style or sensibility?
I was born in Bulgaria and spent much of my childhood there. I've lived several places in the US and currently call Austin TX home. So much of my inspiration comes from being exposed to different lifestyles and cultures and I think having lived in a variety of cities, states and countries gives me a unique view. Plus I LOVE to travel, I have been to over 20 countries, and each trip is an inspiration.
If you were not a designer, what would you be doing for a living?
Creativity is in my blood; I can't imagine having a job where I had to do the same thing every day! So if I had to choose another industry to develop a business, it would be fashion.
What is your greatest strength and weakness as a designer or design manager?
My greatest strength IS my greatest weakness; I can be incredibly OCD and fuss over every detail, wanting it to be perfect. I know our clients appreciate this attention to detail, but it's sometimes challenging to send an item to press and not be stuck in endless revisions.
Favorite Typeface?
It changes daily, but today, it's Compendium.
Favorite TV Shows?
Modern Family, Project Runway and The Apprentice
Favorite Books?
The Glass Castle, all-time favorite!
Favorite Fine Artist?
Todd White
Favorite Gadget?
That's easy, my iPhone.
Bookmarked Websites?
StumbleUpon, DesignWorkLIfe, Mashable and Gilt Groupe.
Worst Habit?
Coming up with too many ideas to execute at a time.
New Year's Resolution?
Read more!
One Thing You Can't Live Without?
Passion for what I do in my career/company.
Mantra or Saying You Live By?
"The secret to getting ahead is getting started"
– Mark Twain


text:
GENEALOGY-DNA-L ArchivesArchiver > GENEALOGY-DNA > 2010-09 > 1284402561
From: John S Walden <>
Subject: Re: [DNA] Experimenting with Family Finder Chromosome Browser
Date: Mon, 13 Sep 2010 14:29:21 -0400
References: <email@example.com>
In-Reply-To: <firstname.lastname@example.com>
This thread got me to pop the issue of common blocks to the top of my list
In my family I have a Family Finder with results that have 59 matches. (all
There is one block that matches 16 others
None of these are in the "Close or Immediate" category of FTDNA
While not all the blocks same they all fall on chromosome 17 from 66 mB to
most of the blocks are in the 8 cM range.
Am I correct that these could actually be two groups
Each group matching one of the two strands in my families chromosome 17?
Is that really likely? I would think these would all be matching the same
Does this mean that all 17 of us have a common ancestor we can look for?
>From what David F posted earlier he would say NO.
On the other hand this has to be more than happenstance and thus should
be researched - right?
Any thoughts on the meaning of this match?
John W
This thread:
|Re: [DNA] Experimenting with Family Finder Chromosome Browser by John S Walden <>


text: Introduction to Health Economics This module is designed to introduce the basic principles of health economics and equip you with the basic knowledge needed to interpret and appraise applied studies in health economics. The course covers issues including health and health care systems, methods of economic evaluation, setting priorities using health economics and the interface between health economics and health policy. Learning outcomes By the end of the module you should be able to: Demonstrate a knowledge of the roles and limitations of markets and incentives in health systems; Distinguish between the different forms of economic evaluation and show an understanding of the advantages and disadvantages of the various approaches; Critically review published economic evaluations of health technologies; Demonstrate an understanding of the techniques used to measure both costs and benefits in the evaluation of health care. Module outline Monday: Introduction to health economics: Issues in health economics; markets, supply and demand; market failure in health care; health economics and priority setting. Tuesday: Key principles of health economics: Welfare economics and social welfare; the demand for and the production of health; need, equity and efficiency. Wednesday: Introduction to economic evaluation part I: Methods of economic evaluation; measuring costs; measuring outcomes; applications and examples. Thursday: Introduction to economic evaluation part II: Dealing with uncertainty and other issues; frameworks for economic evaluation; using economic evaluation. Friday: Setting priorities using health economics: Practical applications; case studies; presentations of group work; group feed-back session. Credits 20 credits Module Attendance Required 1 block week of teaching Module Dates 2016/17 dates: 26th – 30th September 2016 Assessment 2 x 3000 word assignments (50% each) Academics involved in the delivery of this module Professor Tracy Roberts (Professor for Health Economics) Mr Raymond Oppong (Lecturer - Dept of Health Economics) Stand Alone Course This module can be taken as a stand alone course if required. To apply, please see below. For any further information please contact Helen Evans, Senior Administrator, 0121 415 8324, email@example.com To apply for a stand alone course Please complete the application form and make payment here. Fee if taken as a stand alone course 2016/17 module prices UK/EU - £999 (Public Sector), £1499 (Private Sector) Non UK/EU - £1517 This module can be taken on a stand alone basis however it will not be assessed and no credits will be awarded. Entry requirements if taken as a stand alone course There are no specific entry requirements to take this module as a stand alone, non assessed course.


text:
That was an "Obama initiative" in about the same way that Dunkirk was a Churchill initiative.
He began showing some promise in 2003, taking fifth place at race known as the Four Days of Dunkirk in May of that year.
After a brief stay in London a boat was taken to Dunkirk, and the journey resumed towards Lille.
Did we not tell you that Dunkirk bred men of bone and marrow.
There were then in the fall of 1843 four Norwegian families settled in the Town of Dunkirk.
But his sailors were no match for the onrush of these fiends from Dunkirk.
They turned and with their eyes followed the General's finger pointing at the beach at Dunkirk.
At Dunkirk, he is additionally taught how to get rid of them.
As we were fifteen miles from Dunkirk, and as everything had to be brought out from there, transport was a serious problem.
Both Calais and Dunkirk were bombarded by German destroyers.
The scene of a remarkable, though ignominious, retreat by the British army in World War II. Dunkirk, a town on the northern coast of France, was the last refuge of the British during the fall of France, and several hundred naval and civilian vessels took the troops back to England in shifts over three days.
Note: The term Dunkirk is sometimes used to signify a desperate retreat.


text:
GRD Presents Blue October at The Intersection
Additional Information
97.9 GRD presents Blue October on Tuesday, October 22, at The Intersection in downtown Grand Rapids! Tickets are $25 in advance and on sale at SectionLive.com and the Intersection box office. Keep listening to GRD for your shot at winning tickets!
Watch Blue October's "Into The Ocean"
Subscribe to 97.9 WGRD on


text:
Choose your Campsite
How to
get Connected
Using a USB
WiFi Antenna
Using a Large
Outdoor WiFi Antenna
Share your
WiFi Reception with Others
Choose your Campsite
How to
get Connected
Using a USB
WiFi Antenna
Using a Large
Outdoor WiFi Antenna
Share your
WiFi Reception with Others
Free WiFi RV Directories
WiFi FreeSpot RV Park Directory
RVers Online
RVers Computer Help
Omni-Direction RV WiFi Antenna to
Computer USB port
Weatherproofing a USB Antenna
Choose your
Campsite Wisely
Some locations only have a few RV parks
available, but if there are several parks available then try
searching online for web sites that list free WiFi parks in your
area. Once you find one that you like, call in and reserve a site
that is closest to their WiFi access point. Some RV parks will not
let you reserve sites ahead of time and in this case you will have
to figure out which campsite has the strongest WiFi signal.
When you arrive at the RV park ask that attendant were the WiFi
access point is located. After receiving your answer, take out your
WiFi enabled laptop and walk around from site to site in search of
the strongest WiFi signal. Start at the sites that are closest to
the WiFi access point. Usually the signal strength is represented by
a number of bars next to the WiFI network name when scanning with
your laptop. Be sure to press the refresh icon at each site for an
updated signal strength readout.
When looking for a good site, keep in mind that even one tree can
block your WiFi signal. Try to achieve perfect line of sight to the
outdoor WiFi antenna or RV park office from your campsite. If the RV
park is crowded then it is ok to choose a campsite further back as
long as its has good line of sight to the access point and good
signal strength. These two should relate directly to each other.
Once you find a site that has good WiFI signal strength, write down
the campsite number and request it for your stay.
How to Get
So, you've finished setting up camp and
now your ready to get connected the WiFI Internet. At first, try
connecting using just the WiFi capabilities that are built into your
laptop. If you are unable to get a good connection from inside the
RV or motor home then try positioning the laptop in a window that
faces the RV Parks WiFi Access Point. The walls of an RV can block
your WiFi signal completely, this is why we recommend using the
window as a portal for WiFi.
...Using a USB WiFi
Unfortunately holding your laptop up in
the window is not a greatly comfortable position. This can wear on
your arms after only a few minutes. If you
are experiencing this then your solution is a USB WiFi Antenna
this one). A USB WiFI Antenna should be more powerful then your
average laptops built-in WiFi abilities but in some cases newer
laptops do have very powerful antennas. Place the USB antenna in the
window with suction cups or double sided sticky tape and run the USB
cable to your computer.
Avoid Harmful Radiation
USB WiFi antennas are also a great way to avoid
harmful radiation. You will notice that almost every WiFi device has
an FCC RF exposure warning that tells you to keep it at least
8-inches away from your body. Some people worry about the radiation
that is output from their laptop could cause them health problems
because of their close proximity when using it. Using a USB
Antenna with a USB extension cable will lessen the possibility of
exposure to harmful RF because you can place it further away.
Remember to turn off the built-in WiFi on your laptop when using a
USB antenna or you will remain subject to the harmful radiation.
Turn of the built-in WiFi using a switch or button on your laptop.
Weatherproof your USB Antenna
If you are still unable to pickup the WiFi signal then
you may need to place your USB WiFi antenna outside. It will need to
be located above the roof of your RV or motor home for best
reception. Zip ties work well to secure it to a plastic or PVC pole.
We don't recommend mounting it to a metal pole or object as it could
block or lessen your WiFi reception. If you plan on mounting it
permanently outdoors then you will need to weatherproof it. The
easiest way is to use a plastic bag with some tape around the bottom
to keep water out. While effective, this amature job may become an
eyesore on your rig. For a more professional weatherproofing setup,
try enclosing your USB WiFi Antenna in a PVC pipe with end caps. You
can also use vinyl gutter pipe for better results as it has a little
less resistance to WiFi signals. Here is one example of a
PVC pipe enclosure.
...Using a Large
Outdoor WiFi Antenna
For the best possible WiFi RV park
antenna, use a large outdoor WiFi antenna connected to a powerful
WiFi adapter. This will be your solution for receiving WiFi way out
back where others cannot. If this doesn't work then there's not much
else you can do. how to hook up an outdoor wifi antenna
Point-To-Point WiFi Antenna
For the best WiFi antenna setup, hook up an
outdoor Point-to-Point WiFi antenna on your RV or motor home's roof.
This is a directional type antenna and can really bring in hard to
get WiFi. It is not really a "discrete" antenna but it will get the
job done. You will need to reposition it to face toward the WiFi
hotspot at each campground. The trick is trying to figure out how
the WiFi antenna will mount to the RV. Usually these antennas will
come with mounting hardware that includes a "U-bolt" for attaching
it to a pole.
Share your WiFI Reception with Others
Often at an RV park you will meet people
that are not able to catch the WiFi signal because they are out of
range for their WiFi antenna. It is possible to share your WiFi
reception with them by using a WiFi range extender to repeat your
signal to others. Equipment required includes a 8dbi outdoor
omni-directional WiFi antenna, low-loss coax cable, and a WiFi range
extender with a removable antenna.
First mount the antenna above the roof
of your RV in a spot that it is not blocked in any direction by your
RV. Next run the coax cable from the antenna to the WiFi Range
extender that is located inside. You will need to remove the antenna
that comes on the range extender so that you can hook on the coax
cable. Once everything is connected up properly, plug in the power
to the range extender. It will take a minute to start up. Some range
extenders have a button that can be pressed to repeat the strongest
non-password protected WiFi site in range (like
this one ). In this case, just press the button and the range
extender will do the rest.
In some case where there are a lot of
WiFi site the range extender will not repeat the desired site
because another is stronger. In this case you will need to connect
your computer to it and run the setup so that you can pick your
desired WiFi site.
Ideally you do not want to be too close
to the main WiFi site as you may cause too much interference for it
to work properly. You want to be at least 150 feet away from it but
not out of range of the WiFi signal. If the parks WiFi signal is
weak then you will want to be at a closer site.


text:
Latest question:
How do you think the new GigE standards will influence the machine vision industry?
Respond or ask your question now!
Infrared camera systems measure the radiance of temperature. The cameras, lenses, illumination and software that make up the components of these systems have been used for a wide array of applications. From night vision systems for the military to heat detection systems used to alert authorities to potentially sick passengers in airports, infrared systems have many diverse uses.
The applications for these infrared imagers are as diverse as the components themselves.
Cedip Infrared Systems (Fairfield N.J.) announces ORION�an infrared multispectral imaging system capable of producing IR sub-band images at video rate within the SW-MWIR or LWIR regions. The ORION uses the latest state-of-the-art focal plane array (FPA) detector technology along with large dynamic range, real-time electronics to deliver leading-edge results from applications including IR signature analysis, gas detection, flame analysis and environmental studies.The FPA detector is capable of capturing up to 200 high-quality images per second in snap-shot mode. The camera integration time is software variable and can be different for each filter. Using a continuously rotating filter wheel, synchronised with the FPA detector, the ORION captures a single snapshot image for each filter position enabling true multispectral imaging. It also can be used as a standard IR camera by stopping or removing the filter wheel. Image data is processed in real time by the onboard ALTAIR software. www.cedip-
The new Electrophysics (Fairfield, N.J.) PV320L2Z Broadband Infrared Camera features the broadest spectral response of any infrared camera, with 0.6 to 20 micron sensitivity. The camera achieves its broad spectral sensitivity due to a 320x240 uncooled pyroelectric focal plane array. Advanced features also include a USB 2.0 high-speed digital output, internal automatic image calibration (AIC) and a ZnSe non-fringing detector window (for viewing coherent laser sources). The PV320L2Z can be operated as a stand-alone video-based system with on-camera controls. Connect the camera to any USB 2.0 enabled PC platform view/store to analyze real-time images with Velocity Advanced, a powerful real-time image acquisition and analysis software application. The PV320L2Z is ideal for a wide range of spectral imaging applications. www.electrophysics.com.
FLIR Systems (Boston, Mass.) announces the release of its RTools� v2.3 software package for digital infrared camera systems. RTools is a highly sophisticated software package that enables engineers and scientists to easily acquire, radiometrically calibrate, process, and analyze data from various IR cameras. Recent updates to RTools include more powerful analysis features, advanced triggering and recording, compatibility with the FLIR SC8000 IR camera system, and support for dual high-speed data recording. The RTools software suite consists of five separate modules: RDac��an easy-to-use, real-time data acquisition program; RCal� �to radiometrically calibrate infrared cameras; RView��a high-performance, data viewing & analysis module; REdit�� a file archival, editing and maintenance tool; RPro��for data reduction and processing capabilities. These dedicated tools are especially well suited for facilitating the investigation of complex applications with IR camera technology. They provide a seamless real-time interface to FLIR ThermoVision� SC6000/SC4000/SC8000 systems, as well as many other digital IR cameras. RTools can be used with cameras having a variety of detector types, both cooled and uncooled. www.infraredresearchcameras.com.
ICx Technologies (Arlington, Va.) announces the DefendIR thermal imager is now available with Continuous Optical Zoom (CZ) capability. Much like a traditional CCD camera the DefendIR CZ gives the user the ability to change fields of view while keeping the target in focus at all times. Featuring a 30mm-90mm continuous zoom lens, the DefendIR CZ is the first uncooled infrared camera on the market with this type of capability. Paired with ICx's proprietary VisionSense� technology and continuous 360� panning, the DefendIR CZ ensures constant visual awareness that crosses both visible and infrared wavelengths. ICx Technologies proprietary sensors detect and identify chemical, biological, radiological, nuclear and explosive threats, which deliver superior awareness and actionable intelligence for wide-area surveillance, intrusion detection and facility security. www.icxt.com.


text:
EMERALD STAR CRUISE 5TH TO 12TH JULY, 2014: Emerald Star Cruise Review by LEESRE
Overall Member Rating
Destination: Europe - River Cruise
Embarkation: Other
When the tickets arrived we were very surprised to also receive two very good quality back packs, it stated in the pack that these could be used for our hand luggage, and yes they were very useful.
Also in the pack was a fabric zipped wallet with all the instructions and airline tickets etc, much better than a lot of cruise lines with their paper folders.
We had been scheduled a flight from Manchester airport with Lufthansa and we were met in Munich and then transported by luxury coach to Nuremberg to join the ship, (Barge or boat) not sure what to call a River Vessel.
On arrival we were shown to the Lounge as the cabins were not yet available, we could purchase drinks and food as the offer on our cruise started with our evening meal.
When we went down to our cabin we were quite surprised to find it to be very spacious, bathroom was a little on More the small side but adequate.
This tour included all excursions each day, one on the morning and the other in the afternoon, all coffee and teas, which were excellent, also wine, soft drinks or beer, with both lunch and dinner.
The ship was almost new this being the third cruise since it was built, and it showed, everything was very clean and with lots and lots of glass and mirrors. The dining room and the lounge had very large floor to ceiling windows, which let in lots of light and was excellent when you were sailing to view the countryside etc. There was also an indoor swimming pool which turned into a cinema in the evenings.
Each day after dinner there was various entertainment provided, either music from a man playing am organ or entertainers brought onto the ship.
Food was buffet service for breakfast and lunch, and waiter service for dinner. Overall the food was good, my only comment was that sometimes the food was only warm, but this was soon remedied if you asked the Chef for it to be warmed, or for a hot plate for the buffet. Wine flowed there was never any hesitation to refill glasses etc.
I have to say that the organisation of the whole cruise could not be faulted, in our opinion, from the excursions each day to the run of the ship. The staff were exceptional from the Captain down.
Each night we were informed of the next days schedule, both a talk by the cruise director and a paper on the bed after turn down service. All excursions were included in the price, you had a receiver in your cabin and this was used via an ear phone with the tour guide. You could choose which coach you went on and the coaches each had their own guide.
DAY 1. Arrive Nuremberg
DAY 2, Weltenburg - Regensburg. Included excursions Weltenburg Abbey and Regensburg
DAY 3. Passau - Linz Included excursions Walking tour of Passau
DAY 4 Melk – Durnstein Included excursions Melk Abbey and guided tour of Durnstein
DAY 5. Vienna. Included excursions drive along Ringstrasse and walking tour of Vienna.
DAY 6 Bratislava. Included excursions Home hosted afternoon teas with local Slovakian
Family sightseeing tour of Bratislava.
Day 7. Budapest. Included excursions visit to the Fisherman's Bastion and evening cruise along the Danube, evening show of Hungarian folk dancing and music.
DAY 8. Leave for home.
I would thoroughly recommend Emerald Waterways and next year they will be having two new ships to add to their fleet. Less
Published 07/19/14
Cabin review: D Deck106
overall cabin was very good, small bathroom.
Read Cruise Critic's Emerald Star Review >>
Excellent all round
Loved it.
Danube Delights
Much to see and interesting pl...
Danube delights
Excellent all round
Danube Delights
Pre-cruise Chaos but Cruise Ex...
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??? about 8 lug stuff
Discussion in 'The Garage' started by blublaz, Oct 22, 2005.


text:
Crude prices rise on new hurricane threat
New York
Page Tools
CRUDE oil and petrol prices rose as producers in the Gulf of Mexico evacuated staff and shut rigs and platforms in the path of hurricane Rita.
The storm is forecast by the US National Hurricane Centre to cross the Gulf and grow as strong as hurricane Katrina, which wrecked rigs and closed refineries in Louisiana and Mississippi last month. Rita's track is further south than Katrina's and may extend to Texas, which produces a quarter of the US's refined fuel, by Friday.
"Rita is more an issue for refining than it is for production," Adam Sieminski, an oil strategist at Deutsche Bank AG, said yesterday. "There are more refineries in Texas than there are in Louisiana," so damage could possibly be more severe than after hurricane Katrina.
The price of crude oil for November delivery rose $US1.40, to $US67.60 a barrel on the New York Mercantile Exchange. Prices are 42 per cent higher than a year ago. Oil reached a record $US70.85 a barrel in New York on August 30, the day after Katrina hit the Gulf coast.
Texas' 26 refineries have the capacity to process 4.6 million barrels of crude oil a day, or 26 per cent of the US total.
Get The Age home delivered for as little as $2.70 a week*


text:
TEENAGERS showed nerves of steel by standing up and speaking in front of classmates, teachers and parents plus 80 strangers.
The schoolgoers were in teams of three presenting speeches they had written and entered in Leigh Rotary Club's annual "Youth Speaks" competition at Bedford High School.
Teams entered from Wigan, Rochdale, Bury and Merseyside and Lowton C of E High School trio of Leonie Hull, Matthew Davidson and Ellie Digby gave a polished performance on the subject of people having the right to choose when they die.
The judges commended the students for their in-depth research and skilful presentation of an emotive subject which earned them a place in the next round of the competition.
After each speech Leigh Rotarians Gareth Cheesman and Terence Hargreaves-Stead asked questions which the teams had to spontaneously reply to, making an even more nerve-racking experience.
"The quality of the speeches, the introductions and votes of thanks were quite remarkable and will be a stepping stone for these talented youngsters in their later lives," said Rotary Club spokesman Brian Mills.


text:
Hi, I wonder if we just should add a format code like %R or something similar as a replacement for the %X/%X notion. Having to type something like "(uint32) (state->curptr >> 32), (uint32)state->curptr" everywhere is somewhat annoying. Opinions? Andres -- Andres Freund http://www.2ndQuadrant.com/ PostgreSQL Development, 24x7 Support, Training & Services
Next: From: Josh Kupershmidt Date: 2012-07-03 17:46:46 Subject: Re: Posix Shared Mem patch Previous: From: Dimitri Fontaine Date: 2012-07-03 17:31:39 Subject: Re: Event Triggers reduced, v1


text:
Red Sox fight by Astros
Associated Press
BOSTON — John Lackey returned from the disabled list and pitched six solid innings, David Ortiz drove in two more runs and the Boston Red Sox matched a team record with their 18th win in April by beating the Houston Astros 6-1 Sunday for a four-game sweep.
Lackey (1-1) missed all of last season recovering from Tommy John surgery and went on the DL after leaving his first start this year with a strained right biceps. He allowed five hits, struck out four and walked two. The walks came with two outs in the first and cost Lackey his only run.
Stephen Drew hit a two-run triple and Ortiz had two hits, extending his hitting streak to 20 games dating to last season. Ortiz has 11 RBIs and is batting .516 in eight games since returning to the lineup last weekend.
Bud Norris (3-3) struck out six for Houston and held the Red Sox to three earned runs.
CHICAGO — David Price struck out nine in winning for first time this season, Ben Zobrist hit a go-ahead RBI single in a three-run eighth spurred by Alex Rios' error and Tampa Bay beat Chicago in a game marked by a spat between Price and home plate umpire Tom Hallion.
Price (1-2) allowed three runs and six hits in seven innings. The 2012 AL Cy Young Award winner walked two and threw 119 pitches.
Price and Hallion exchanged words as Price walked toward the dugout after throwing his last pitch. After the game, Price said Hallion used an expletive. Hallion called Price a liar.
NEW YORK — Lyle Overbay sent a knuckleball from R.A. Dickey into the right field bullpen for a go-ahead, two-run homer in the seventh inning and New York completed a four-game sweep of Toronto.
Brennan Boesch homered in the second off Dickey (2-4), pitching in New York for the first time since getting his 20th win for the New York Mets last September.
Dickey allowed a single to Overbay later in the second, then retired 13 of his next 14 batters around a walk. Travis Hafner singled leading off the seventh and, with two outs, Overbay hit his third home run of the season — one more than his total last year.
MINNEAPOLIS — Kevin Correia pitched eight sharp innings, Justin Morneau homered and Minnesota sent Texas to a second straight loss for the first time this season.
Correia (3-1) gave up six hits, struck out two and walked one. He allowed only one runner to reach third base while lowering his ERA to 2.23.
The soft-tossing veteran signed a two-year, $10 million contract with Minnesota in the offseason and has been the Twins' best starter. Using a fastball that rarely broke 90 mph and a variety of offspeed pitches, Correia retired his first seven batters and set down 11 of the last 12.
Alexi Ogando (2-2) allowed three runs on four hits over six innings.
OAKLAND, Calif. — Third baseman Manny Machado made a throwing error on a bunt in the 10th inning and Oakland completed its comeback to snap a four-game skid and keep Baltimore from a four-game sweep.
Down 5-0 in the sixth, the A's tied it at 8 on Yoenis Cespedes' two-run homer with one out in the ninth.
Eric Sogard hit a leadoff single in the 10th and moved to second when reliever Pedro Strop (0-1) made a wide throw to second on Adam Rosales' bunt. Coco Crisp followed with a sacrifice bunt and Machado threw wildly past to shortstop J.J. Hardy covering third, allowing Sogard to score with a headfirst dive.
Chris Davis hit his team-leading ninth home run, a solo shot in the eighth that put Baltimore ahead 7-6. Machado added an RBI double in the ninth.
Jerry Blevins (1-0) pitched one inning for the win.
SEATTLE — Jason Bay and Michael Morse hit solo home runs and Seattle took three of four from Los Angeles to earn its first series victory of the year.
Bay tied it in the seventh with his second homer, connecting on the first pitch of the inning from Jason Vargas (0-3).
Morse put Seattle ahead in the eighth against Vargas, hitting his seventh home run into the Angels' bullpen.
Mariners starter Hisashi Iwakuma struck out eight over six innings, allowing only an unearned run.
Carter Capps (2-1) got the victory and Tom Wilhelmsen closed for his ninth save.
KANSAS CITY, Mo. — Jeremy Guthrie kept Cleveland off-balance, Alcides Escobar and Alex Gordon homered, and Kansas City romped in the opener of the first day-night doubleheader in the history of Kauffman Stadium.
The doubleheader was caused by a rainout Friday night.
Guthrie (3-0) allowed six hits over 6 2-3 innings for his 16th consecutive start without a loss, tying the Royals' record set by Paul Splittorff from Aug. 13, 1977-April 22, 1978.
Escobar's solo shot came in the fifth inning and Gordon's two-run homer came in the eighth. Jarrod Dyson also drove in a pair of runs, and Mike Moustakas had a single and three walks — one with the bases loaded.
Justin Masterson (4-2) allowed seven runs in 6 1-3 innings for the Indians.
ST. LOUIS — Rookie Jeff Locke pitched seven innings of three-hit ball and Russell Martin had two of Pittsburgh's four home runs in a 9-0 victory over the St. Louis Cardinals that gave the Pirates a series win and the NL Central lead.
Jones had three hits and John McDonald added an RBI double for Pittsburgh, which ended rookie Shelby Miller's streak of 14 scoreless innings at home to start the season. The Pirates have won nine of 12 overall, leapfrogging St. Louis for first place.
Locke (3-1) has worked 13 scoreless innings while allowing five hits his last two starts. The Cardinals got just three singles and advanced two runners into scoring position against the 25-year-old left-hander, who earned the fifth spot in the rotation with a strong spring.
Justin Wilson allowed a walk the last two innings to wrap up the Pirates' fifth shutout, tied for the league lead with St. Louis and San Francisco.
Miller (3-2) struggled to put away hitters and was taken out after 113 pitches and giving up two homers in 5 2-3 innings.
MIAMI — Giancarlo Stanton homered twice and drove in four runs, helping the Marlins avert a four-game series sweep.
Ricky Nolasco (2-2) gave up three runs in seven innings and retired the final 15 batters he faced. The Marlins improved to 6-19, still worst in the majors, and 3-10 at home.
They benefited from a rare offensive outburst, scoring more than three runs for only the fifth time this season and twice coming from behind.
Stanton waited 65 at-bats to hit his first homer Saturday, then hit another in the first inning off Carlos Villanueva (1-1) to put Miami ahead 2-1. He homered again leading off in the eighth against Kameron Loe.
Chicago's Dioner Navarro went deep in the ninth against Steve Cishek, who nonetheless earned his third save in four chances.
NEW YORK — Ryan Howard snapped a seventh-inning tie with a pinch-hit double, Cole Hamels earned his first win of the season and the Phillies took advantage of a crucial Mets error to finish a three-game sweep.
Freddy Galvis homered, Chase Utley had an RBI single and Hamels (1-3) overcame six walks, which matched his career high. The left-hander held the Mets to two hits and struck out eight over six innings in his fourth consecutive solid outing.
All-Star catcher Carlos Ruiz went 1 for 4 with a double in his return to the Phillies from a 25-game amphetamine suspension. Even on the road, the popular Ruiz was greeted warmly with a chorus of "Choooooch," and one fan held a sign welcoming him back.
Jonathon Niese (2-2) allowed one earned run in 6 2-3 innings for New York, showing no ill effects from the comebacker that hit him near the right ankle and knocked him out of his previous start Tuesday.
WASHINGTON — Tony Cingrani struck out a career-high 11 — including four in one inning — while pitching two-hit ball through the sixth, and the Reds avoided a four-game series sweep.
Brandon Phillips had a two-run single as the Reds (14-12) improved to a major league-worst 2-9 on the road.
Cingrani (2-0) pitched three perfect innings before Denard Span reached leading off the fourth on a strikeout and wild pitch. Danny Espinosa followed with a double, but Cingrani struck out three more hitters to escape the inning without allowing any runs.
He joined Joe Nuxhall, Mario Soto, Tim Birtsas and Frankie Rodriguez as the only Reds with a four-strikeout inning.
Washington's Ross Detwiler (1-2) allowed three earned runs in five innings, and his 11 hits allowed matched a career high.
Aroldis Chapman earned his fifth save in five opportunities.
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text:
Dr. Dre isn't suffering in this crazy economy.
The rapper, producer and record exec has sold 51% of his audio company Beats Electronics to smartphone manufacturers HTC for $309 million, according to NME.
He set up the company in 2006 with Geffen Records executive Jimmy Iovine and has since launched high-end headphones endorsed by Lady Gaga, Justin Bieber and Diddy, who each put their name to their own signature headphones.
Dr. Dre is currently putting the finishing touches to his new album, Detox, which is due out later this year. It will be his first since 1999.
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