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These authors contribute equally to this work.
This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
Pancreatic cancer is one of the most lethal malignancies with poor prognosis. Previously, we found that a subpopulation of cancer stem cells (CSCs) in the Panc-1 pancreatic cancer cell line could propagate to form spheres. Here we characterized the malignant phenotypes of the pancreatic cancer stem CD44+/CD24+ cells, which were enriched under sphere forming conditions as analyzed by flow cytometry. These cells demonstrated increased resistance to gemcitabine and increased migration ability. Moreover, these cells exhibited epithelial to mesenchymal transition characterized by a decreased level of the epithelial marker E-cadherin and an increased level of the mesenchymal marker vimentin. Notably, abnormal expression of Bmi-1, ABCG2, Cyclin D1 and p16 were found in Panc-1 CSCs. Our results suggest that targeted inhibition of CSCs represents a novel therapeutic approach to overcome chemoresistance and metastasis of pancreatic cancer.
Pancreatic cancer is currently the fourth leading cause of cancer-related mortality in Western countries. Despite advances in tumor biology and the development of cancer therapeutic strategies, the prognosis of pancreatic cancers remains miserable, with the five year survival rate less than 5% [
The discovery of cancer stem cells (CSCs) has changed our view of carcinogenesis and cancer therapy. It is proposed that subgroups of cancer stem cells within the tumor sustain the formation and growth of the tumor and account for tumor recurrence due to their self-renewal and differentiation abilities, metastatic potential, and resistance to conventional therapeutics [
In a previous study, we found that a subpopulation of cells in the Panc-1 pancreatic cancer cell line could propagate to form spheres, and strikingly these cells exhibit features of CSCs such as extensive self-renewal, proliferation, differentiation, and tumorigenesis [
Cell surface markers have been widely used to isolate stem cells. The surface markers CD44, CD24, and ESA have been well defined for isolating CSCs from primary pancreatic adenocarcinomas [
As the first step to characterize the phenotypes of the pancreatic CSCs, we sought to determine their chemosensitivity. Both Panc-1 cells and Panc-1 CSC were exposed to the most widely used chemotherapeutic agent: gemcitabine. The cell viability was determined by MTT assay and the results demonstrated that while Gemcitabine inhibited the proliferation of Panc-1 cells and Panc-1 CSC in a dose dependent manner, Panc-1 CSCs showed a relative resistance to gemcitabine compared to Panc-1 cells cultured in monolayer, and the difference between the growth inhibition rate of these two groups was statistically significant (P < 0.05) (
Recent evidence suggests that CSCs may drive the progression and metastasis of malignant cancer [
Tumor metastasis is often correlated with loss of epithelial properties and acquisition of the fibroblast-like phenotype of cancer cells, a phenomenon known as EMT [
We further explored the possible mechanisms responsible for the malignant phenotypes of Panc-1 CSCs as shown above. Multidrug resistance is an important mechanism for pancreatic cancer to acquire chemoresistance and ATP-binding cassette (ABC) transporters participate in pumping the drug out of the cancer cells and endowing multidrug resistance. By Western blot analysis, we found that ABCG2/BCRP1 was overexpressed in Panc-1 CSCs compared to Panc-1 cells. In addition, Cyclin D1, an important regulator of cell cycle progression and proliferation, was overexpressed in Panc-1 CSCs. p16, one of the important regulators of cellular senescence and apoptosis, was downregulated in Panc-1 CSCs. Bmi-1, which is an oncogene and stem cell renewal factor, was also highly expressed in Panc-1 CSCs (
The cancer stem cell theory posits that a small population of progenitors with extensive self-renewal properties determines the initiation and behavior of tumors. Mounting evidence has demonstrated the important role that cancer stem cells play in tumor initiation, maintenance, progression and recurrence [
We further explored the possible mechanisms by which the resistance to chemotherapy may be regulated in Panc-1 CSCs. The epigenetic regulator Bmi-1 belongs to the polycomb group family, which plays essential roles in the self-renewal and propagation of normal and cancer stem cells [
Interestingly, we found that the expression of the ABC transporter ABCG2 was increased in Panc-1 CSCs compared to Panc-1 cells cultured in monolayer. ABCG2 belongs to the ABC transporter family, which protects cells by pumping a variety of cytotoxic agents out of the cells. This property endows the multidrug resistance to cancer cells and is a major obstacle to successful cancer chemotherapy [
Our results also demonstrate that p16, a regulator of cell senescence and cell cycle, was downregulated in Panc-1 CSCs. Loss of p16 function may be involved in the carcinogenesis and aggressive behavior of pancreatic cancer [
Cyclin D1 is an important regulator of cell cycle progression. The overexpression of cyclin D1 has been linked to the development and progression of pancreatic cancer through promoting abnormal growth and resistance to chemotherapy [
Recent evidence has supported the link of chemoresistance and EMT with stem cell phenotype [
The pancreatic cancer cell line Panc-1 originated from ATCC (Manassas, VA, USA), and was cultured in DMEM supplemented with 10% fetal bovine serum, 100 U/mL pencillin and 100 U/mL streptomycin at 37 °C with 5% CO2. The culture conditions for Panc-1 cells to form tumor spheres in suspension was as described previously [
Panc-1 cells were dissociated with trypsin-EDTA solution (trypsin, 0.25%; EDTA, 0.02%) and washed twice with phosphate-buffered saline (PBS) and resuspended in PBS at a density of 1 × 106 cells/100 μL. The dissolved cells were stained using APC antihuman CD44, PE anti-human CD24 and ESA-FITC (Biolegend) at a dilution of 1:40, incubated for 20 min on ice and then washed twice with PBS. The respective isotype controls were used at concentrations according to the manufacturer's instruction. The samples were analyzed on a flow cytometer (BD LSR II, America) and the data were analyzed with the BD FACS Diva software.
Three groups were divided: blank group (no cells), control group (no treatment), experiment group (gemcitabine treatment). Cells were plated in 96 well plates with a density of 10,000 cells/well. 24 h later the cells were incubated with medium containing various concentration of gemcitabine (Eli Lilly) for 48 h. Then 5 mg/mL of 3-(4,5-dim ethylthiazol-2-yl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) (Sigma) was added to each well. After incubation for 4 h, the supernatant was replaced with 150 μL of dimethyl sulfoxide (Sigma). The absorption (A) was read at 490 nm using a spectrophotometer. The inhibition rate of cell proliferation was calculated as: (Acontrol − Ablank) − (AexperimentAblank)/(Acontrol − Ablank) × 100%. The experiments were performed in triplicate and repeated twice.
The migration assay was performed using transwell cell culture chambers (8 μM pore size polycarbonate membrane, Costar). Briefly, cells were resuspended in DMEM with 1% FBS to a concentration of 5 × 105/mL. The upper chamber was loaded with 100 μL of cell suspension and the lower chamber was loaded with 600 μL of DMEM with 20% FBS. After incubation for 24 h at 37 °C with 5% CO2, the filter was fixed with 4% paraformaldehyde and stained with hemaroxylin. The cells on the upper side of the filter were wiped off with a cotton swab. The cells migrated to the undersurface of the membrane were counted under microscope. Ten microscopic fields (400×) were randomly selected to count cells. Each assay was done in triplicate.
Pancreatic cancer cells were lysed in lysis buffer (20 mM Tris pH 7.5, 150 mM NaCl, 1% Triton X-100, 0.1% NP40, 0.5% sodium deoxycholate, 1 mM of phenylmethylsulfonyl fluoride and gabexate mesilate). The protein concentration of the lysate was quantitated by BSA method. Equal amounts of lysate were loaded and separated by SDS-polyacrylamide gels, and transferred onto nitrocellulose membranes. The membranes were blocked with 5% non-fat milk powder in TBS for 1 h and probed with primary antibodies against vimentin (Sigma, 1:200 dilution), E-cadherin (Santa Cruz, 1:500 dilution), p16 (Santa Cruz, 1:400 dilution), ABCG2 (Santa Cruz, 1:300 dilution) or GAPDH (ProMab, 1:8000 dilution). After washing with TBS-T, the membrane was incubated with secondary horseradish peroxidase-coupled antibodies and visualized using enhanced chemiluminescence.
The differences between different groups were evaluated using the Student's t test. P < 0.05 was considered significant.
In summary, our results indicate that cancer stem cells are enriched in Panc-1 spheres and they demonstrate an EMT phenotype and increased resistance to gemcitabine and motility. Overexpression of Bmi-1, ABCG2 and cyclin D1 and downregulation of p16 could contribute to these phenotypic changes of Panc-1 cancer stem cells.
This study was supported by grants from the National Natural Science Foundation of China. (No.30801100), Ph.D. Programs Foundation of Ministry of Education of China (No. 200804871112), the Hubei Key Laboratory of Biological Targeted Therapy of China (2007B09) and Young Scientists Funds of Health Department of Hubei Province (QJX2008-8).
The Panc-1 cell cancer stem cell (CSC) subpopulation (CD44+/CD24+) was enriched under sphere-forming conditions. The right upper quadrant (Q2-2) indicates the distribution of the CD44+/CD24+ subgroup of cells as analyzed by flow cytometry. The experiment was repeated 5 times and the data are expressed as mean ± standard deviation, statistically significant differences were determined by Student's t test, the difference between the Panc-1 group and the Panc-1 CSC group was significant, p < 0.05.
Panc-1 CSCs have increased chemoresistance to gemcitabine. Panc-1 CSCs or Panc-1 cells were treated with various dosages of gemcitabine for 48 h. Cell viability was determined by MTT assay. Panc-1 CSCs showed increased resistance to gemcitabine compared to Panc-1 cells cultured in monolayer.
Panc-1 CSCs have increased migration ability. The migration of Panc-1 CSCs or Panc-1 cells was determined by transwell migration assay. After the filter was fixed and stained, the number of cells migrated to the undersurface of the filter was compared. Left side: Panc-1 CSCs had increased migration ability compared to Panc-1 cells, (40× fold). * p < 0.05. Right side: images of Panc-1 cells (top) and Panc-1 CSCs (bottom).
Panc-1 CSCs demonstrate a phenotype suggestive of epithelial to mesenchymal transition (EMT). The expression levels of E-cadherin and vimentin in Panc-1 CSCs and Panc-1 cells were determined by Western blot analysis (left). Densitometry analysis revealed the differences between Panc-1 CSCs and Panc-1 cells (right). * p < 0.05.
Abnormal expression of Bmi-1, ABCG2, Cyclin D1 and p16 in Panc-1 CSCs. The levels of Bmi-1, ABCG2 and p16 in Panc-1 CSCs and Panc-1 cells were determined by Western blot analysis and normalized to GAPDH (left). Densitometry analysis revealed the differences between Panc-1 CSCs and Panc-1 cells. * p < 0.05.


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Free Cake Baking Tips
Seeing so many people get discouraged over baking inspired me to compile a library of the best baking tips and tricks that ensure a perfect cake every time...
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subset: commoncrawl


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54kg/156cm Oringinal Small B Cup and Just Got 305cc I Regret Not Getting 325cc. After one week my breast already fall softer. They are not too high above my chest and already look natural.. Are they supposed to feel soft already.. Still little pain but bearable.. My friend got hers same time as me, and she is in more pain and her boobs are still very hard so I'm worried why mine have softened a little and numbing has gone.. They still look big as they originally did after surgery. Should I be worried if they softened to early?
Doctor Answers 7
Softness soon after surgery.
1 Week PO, Did My Boobs Soften Too Early?
I would not have any concern about the implants feeling normal this early. Every patients recovery is different, and depends on many factors. I would fret about 20 cc--less than half a shot glass. It is doubtful that 20 cc would make a noticeable difference. All the best.
Breast softening
Everyone heals at a different rate and can have different post-op results and symptoms. I would not worry too much and just allow the healing process to progress.
You might also like...
#Breasts Softening too Early After #BreastAugmentation
Your breasts being soft is not an issue, however the implant volume could be. If they look too small already - at one week, they are not going to get bigger with time. Choosing the appropriate sized implant is critical to success, but you should wait to allow the implants to fully settle before deciding what to do next.
Continue to follow up with your surgeon to ensure that you progress as planned.
Best of luck,
Vincent Marin, MD
San Diego Plastic Surgeon
Learn more: http://www.marinaesthetics.com/breast-augmentation/
Swelling resolves at different rates in breast augmentation patients.
Consider yourself lucky if your breasts are soft soon after surgery. This is not a problem but just a potential outcome.
Learn more: http://www.zubowicz.com/subpag,13-atlanta-breast-augmentation.htm
Soft breasts are great
It sounds as though you are doing great and do not need to worry. It is possible that you are doing well because you did not go with larger implants.It usually takes larger implants longer to become soft, and even with time larger implants often never get as soft as smaller implants. Also, larger implants often lie higher on the chest initially.
Did My Boobs Soften Too Early after Breast Augmentation?
No, you should not worry; if anything, it sounds like you are doing quite well. Enjoy the outcome of the procedure performed.
Best wishes.
Learn more: http://www.poustiplasticsurgery.com/Procedures/Procedure_breastAugmentation.htm
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


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Ive lost the wire off my bra in the washing machine, how do i find it before it breaks my machine?
Try the filter.
Who invented a machine called a lasting machine that stitched the leather of a shoe to its sole?
Jan Ernst Matzeliger invented the lasting machine. The lasting machine places and attaches the leather upper part of the shoe to the sole. A native of Dutch Guiana born in 1852, Matzeliger develope...
Read More »
Need a wood cabinet for Kenmore sewing machine model 148-280 and how old is this machine and what is it worth?
Used Kenmore sewing cabinets sell for between $10 - 20. I'm unsure of the exact year your machine was manufactured but the resale value of this sewing machine is approximately zero ($0.00). There i...
Read More »
How to Change a Washing Machine Filter when the Machine Is Full?
This is a messy job but sometimes you have no choice but to clear the filter in a washing machine while it is still full of water if your washing machine stops working because of a blockage. This a...
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Which part of the sewing machine regulates the operation of the machine?
While different parts control different operations on a sewing machine, such as the feed dogs that pull fabric under the presser foot, the main part regulating sewing machine operation is the foot ...
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Location: Huntsville, AL
Member since 8/13/2010
- 1 total post
- 1 comment
Recent comments from Telescope
Thanks for posting. I'm 42 with 2 kids in grade school and am in pretty good shape but I had a pad of fat under my belly button that just wouldn't go away. I thought my only option was a tummy tuck and I didn't want full abdominal... READ COMMENT


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Somerset Co. man pleads guilty to voluntary manslaughter
Somerset County
Man pleads guilty to voluntary manslaughter
A Meyersdale man avoided a potential life sentence under a plea agreement Wednesday when he agreed to plead guilty to voluntary manslaughter in connection with the choking death of his ex-girlfriend in 2012.
Jonathan Beal, 24, of Meyersdale also pleaded guilty to abuse of a corpse and tampering with evidence for burying the body of 19-year-old Justine Jackson near the Great Allegheny Passage hiking and biking trail outside Meyersdale.
Her remains were found Nov. 11, nearly two months after the date Beal acknowledged killing her — Sept. 14, 2012.
The potential maximum prison sentence for voluntary manslaughter is 10 to 20 years. Beal, who originally was charged with murder, could have faced a mandatory life sentence if he were convicted of first-degree murder
Somerset County public defender Steve Miller said Beal didn't mean to kill Jackson when they argued about whether to reconcile, according to The Associated Press. Miller says Beal didn't want to resume their relationship.
District Attorney Lisa Lazzari-Strasiser said prosecutors agreed to the lesser charge because they weren't sure they could prove Beal intended to kill, according to wire reports.
Judge John Cascio ordered a pre-sentence investigation and scheduled sentencing at 9 a.m. Nov. 26.


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NEW YORK (The Deal) -- A top Securities and Exchange Commission regulator acknowledged Friday that certain types of market-moving tweets by startup or fund executives could inadvertently disqualify a company from raising capital for 12 months as part of an investor protection requirement under review by the agency for ad-friendly private deals.
"We recognize in the proposal that there could be inadvertent tripping, so it is an issue that we are aware of," Keith Higgins, director of the SEC's Corporation Finance unit, told The Deal after speaking at a conference in Washington. "Under the rule as proposed it would be problematic. That was the proposal. We recognize that people might not know what a general solicitation is, that it could be inadvertent, and we've gotten a lot of helpful comments on it."
At issue is an SEC proposal that would increase protections for investors when they allocate capital to startup businesses, buyout shops and hedge funds that employ a new rule allowing them to publicly advertise private placements. The proposal would increase obligations associated with an SEC filing requirement known as Form D, which is available publicly on the agency's website and reports who is making an offer, its size and other details.
Firms and funds raising capital privately aren't punished for failing to file a Form D, and many don't. The SEC has proposed to toughen the Form D filing requirement as an added investor protection following the 2012 JOBS Act's removal of restrictions on advertising for private placements.
Startups and angel groups, in particular, are concerned about a provision that would require them to file about a wide variety of "communications," potentially including market-moving tweets, as soon as they make them or even perhaps in advance. Failure to file the material on time would disqualify a firm from raising capital for 12 months. That's an eternity for emerging companies, who argue that it could drive their businesses into bankruptcy.
Marianne Hudson, executive director of the Angel Capital Association, argued on the sidelines of the conference, which was held by the Angel Capital Association, that the disqualification provision is hugely problematic. She said startup companies would like to see some sort of ability to appeal a disqualification before a firm is prohibited from raising capital for 12 months.
Higgins said the issue is on the agency's list. "We know it is something that we have to accommodate and fix and make work," he said.


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AntonioGPh... Photographer
Marques RModel Male Mableton, Georgia, US
My Website: facebookMy MM URL: http://www.modelmayhem.com/marq1792
Mayhem # 2732598
About MeHello Model Mayhem. My name is Marques and I am back in action. I've been modeling for almost 2 years now and I'm getting ready of a change this year. I had to put it on hold because of personal issue now I'm back and ready. I am also a singer too so anything that is dealing with music will definitely work. If interest in working with me just inbox me and I will get back to ASAP. :-)
-Twitter: @youngsouljerguy
-Instagram: king.model & marqthemodel
Have you worked with Marques R? Add Credits for Marques R! >>
Credit Notes-IDream Croture Fashion Show 2013
AntonioGPh... Photographer
akis photography Photographer
JVLADIMIR Photographer
IAMCarlosF... Model
Barins Photography Photographer
King 1031 Photography Photographer
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Beaded Knitted Scarf by Jane Davis
Welcome! You are browsing as a guestWould you like to see 6 projects made from this pattern and much more? create a free account What am I missing?
Beaded Knitted Scarf
Pattern Notes:
Description: This scarf is begun at the center of the scarf. Knit in seed stitch to one end. You then slide pre-strung beads into a variation of plaited and twisted stockinette stitch to create an elegant bead pattern. Add a delicate bead fringe and you will have created a fabulous bead knitted scarf.
Finished size: 8" x 52", not including fringe. You'll also need 96 grams or 3 1/2 oz. of size 6 purl toned seed beads, 28 grams or 1 oz. size 11 purl toned seed beads, DMC perle cotton size 12 or beading thread size B or D. Bead resource given on pattern.


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Joseph A. Rogers, Executive Director
Joseph A. Rogers joined Mental Health Association of Southeastern Pennsylvania (MHASP) in 1984 and was appointed executive director in July, 1997. Rogers' work has included setting up more than two dozen consumer-run programs at MHASP, organizing the first national consumer conference, and advocating for the closure of state hospitals and the creation of community support services.
Rogers has testified before Congress on patients' rights issues. He served on the Congressional Task Force on the Rights and Empowerment of Americans with Disabilities, which was instrumental in getting the landmark American with Disabilities Act passed, and on the Executive Committee of the President's Committee on Employment of People with Disabilities. He is a past president of the board of directors and a former chairman of the advisory board of Pennsylvania Protection & Advocacy Inc.
Rogers has frequently served as a consultant on consumer issues both here and abroad. He was an invited speaker in 1987 at the World Congress for Mental Health in Cairo, Egypt, and at the 1989 World Congress in New Zealand. In 1993, 1994 and 1995, he provided technical assistance to Poland's growing consumer movement, and met there with consumers, service providers and government officials.
Rogers has appeared on numerous television and radio shows, ranging from the Oprah Winfrey Show to Science Friday on National Public Radio, to talk about consumer issues and the rights of people with mental illness.


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By Jeffrey Gold, AP Business Writer
NEWARK, N.J. Diversified manufacturer Honeywell International Inc. reported a 17.8 percent rise in fourth-quarter profit while recording growth in all four of its business segments. Its stock rose almost 4 percent Friday.
The Morris Township-based company late Thursday said it earned $689 million, or 91 cents per share, for the three months that ended Dec. 31, up from $585 million, or 72 cents per share, a year earlier.
The company had projected net income of 89 cents to 91 cents a share, while analysts surveyed by Thomson Financial were expecting 91 cents a share.
Fourth-quarter sales gained 12.1 percent to $9.28 billion from $8.28 billion in the same period a year ago. The analysts had projected sales of $8.94 billion.
Sales in aerospace, Honeywell's largest segment, rose 10.6 percent to $3.27 billion.
Sales for the automation and controls segment gained 13 percent to $3.44 billion, while transportation systems sales increased 11.1 percent to $1.33 billion. Specialty materials sales rose 14.5 percent to $1.24 billion.
"Our great positions in good industries, together with favorable macro trends, drove growth across each of our four business segments in 2007," Honeywell Chairman and CEO Dave Cote said in a statement.
"While we anticipate softer global economic conditions in 2008, we remain confident in Honeywell's ability to outperform," Cote said. "We will continue to invest in innovation, expand globally, and execute on productivity initiatives to drive double digit earnings per share growth and higher free cash flow in 2008."
Honeywell's contingency plans for an economic slump focus on deferring spending, Chief Financial Officer Dave Anderson said Friday.
"Each of our businesses is prepared to delay some investment spending," Anderson said. Asked if the plans include layoffs, Anderson said, "They could, but more than likely it would be spending in R&D, selling a major investment ... the launch of a new product."
Anderson noted that 60 percent of Honeywell's revenue growth in 2007 came from outside the Americas, a proportion that is likely to increase.
"The company will become increasingly international. The U.S. will always be an important market for us and will continue to grow, but the international markets are growing at a greater rate ... and we are increasing our presence there," he said.
Analyst David Lee Smith at The Motley Fool agreed. "The international is carrying the day," Smith said, adding Honeywell to a list of companies, including Caterpillar Inc. on Friday, that have not reported overseas pullback.
Analysts generally applauded Honeywell's results, with Jeffrey T. Sprague of Citigroup praising the cash flow.
The company reaffirmed its 2008 guidance, issued last month, of $36.1 billion to $36.7 billion in annual sales, with earnings per share of $3.65 to $3.80.
For the full year, Honeywell's profits rose 17 percent to $2.4 billion, or $3.16 a share, compared to $2.08 billion, or $2.52 a share, in 2006. Revenues rose 10.3 percent to $34.59 billion from $31.37 billion.
Its shares rose $2.05, or 3.7 percent, to $58.25 Friday. The stock has traded from $43.14 to $62.29 over the past year.
Copyright 2008 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Avenguard Greece
AVENGUARD is a one man metal band.
I am marching in the metal fields the last 20 years with the 6 string lady by my side...
Also mixing, editing and arranging my songs via sequencer in my personal studio.
Guitar player and songwriter
Metal Greetings from Greece ... more
Streaming and Download help


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This game was classified by the community with the following category scores - Violence=0/3, Sex=0/3, Mature Content=0/3. Practice your math while picking Apples from the Apple Orchard. Fill the Apple Tree with 10 Apples and learn your score!
Buy Xbox content on Xbox.com. Your Xbox 360 console will automatically download the content next time you turn it on and connect to Xbox Live.Learn More
Click to create and send a link using your email application


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Build a Website for Medical consultation with doctors
Budget $250-750 USD
I want to get an experienced freelancer to build a website where users (patients) can meet doctors online, get recommended to labs registered on the website and also schedule an appointment with doctors. The website will also serve for real time consultation and patients can chat and have video sessions at scheduled time.
84 Freelancer bietetn im Durchschnitt $581 für diesen Job an
Good day, We can do this project for you!!! Make an impact with the top notch design; we are ready to work on your project. We offer professional services of innovative graphic design at a very reasonable price. O Mehr
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Hi, I can assist you with this project. Here is a sampling of the few of my work contained at my portfolio: http://www.divulgetechnologies.com/ Please reply back so we can discuss. Regards, DT
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HI, -We will provide responsive WordPress theme please share more detail for your website. -All modules will be fully managed from an admin. -Please share how many pages do you need?if you have any reference webs Mehr
Dear Sir, Is this possible for you to available on freelancer chat so we can discus more about your project positively. Waiting for your reply Thanks & Regards, Gaurav Sharma
Hello, We have gone through your requirement and are confident that we can successfully execute the project within the timeline. We are an established Web Design, Web Development & Mobile Apps Development Company ha Mehr
Hi there, I read the requirements and I am happy to assist you on your project, I am Albert and I have 5+ years of experience in Web Development, I can assure you about quality work and you will receive fast and Mehr
Hello, my name is Olya. I got acquainted with Your description of the task, ready to create Your website for medical consultation with doctors as soon as You need. However, I shall discuss about the requirements and Mehr
We are happy to discuss our proposal with you. KEY POINTS THAT MAKE US DIFFER FROM OTHERS: ~ We have 5+ years of experiences in Unity 3D, Xcode, CoCoa 2d, Phonegap and major iOS and Android developement. ~ 150+ su Mehr
Dear Client , We gone through project description We are Really intrested to do work with you , We are Web & Software development company having more than 8 year experience in Software development we totally commit Mehr


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Snakes Alive!
This optical illusion was created in September 2009 by Akiyoshi KITAOKA, Professor in the Department of Psychology, Ritsumeikan University, Kyoto, Japan.
He calls the illusions 'Morays', and observes that the top and bottom snakes appear to be moving to the right, while the middle two snakes appear to be moving to the left.
Professor Kitaoka owns the copyright of this image. You can see more illusions on his web site.


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Few fighters have had more of a roller-coaster career of late than Brian Viloria. In August 2006, Viloria -- a Hawaiian of Filipino descent -- had a 108-pound belt, an undefeated record through 19 fights, a strong and growing fan base, an exciting style in the ring and, in the form of the old "Hawaii Five-0" theme, the catchiest ring entrance music in the business.
Then he ran into Omar Nino Romero. Looking surprisingly flat and uninspired, Viloria struggled with his Mexican opponent, dropping a unanimous decision and losing his belt. Three months later, he and Romero fought to a majority draw that was later called a no-contest after Romero flunked a drug test. Viloria's old title was declared vacant, but in his third consecutive disappointing outing, he failed to win it back when he dropped a majority decision to Edgar Sosa in April 2007.
Two years later, "Hawaiian Punch" seemed reborn, capturing a belt with a late stoppage of Ulises Solis; and then just like that, it all looked over again after a 12th-round TKO loss to unheralded Carlos Tamara.
But now Viloria's career has entered a third act. He moved up to 112 pounds, won another title and, in his most recent outing, defended his belt in an impressive eighth-round stoppage of Giovani Segura. On Saturday, he will meet Romero for the third time, this time in Manila, in a bout that will be shown in the United States on Integrated Sports PPV. Should he finally dispatch his nemesis, plenty of interesting opponents await Viloria. Here are five:
Edgar Sosa (45-7, 27 KOs). Two years after defeating Viloria to annex a junior flyweight title, Sosa lost it inside two rounds to Rodel Mayol and was outpointed in his only subsequent title tilt by longtime champ Pongsaklek Wonjongkam. But Sosa remains a credible contender, and if Viloria can avenge his first defeat, what better way to show that this time he's for real than by reversing his second loss?
Hernan Marquez (33-2, 25 KOs). In ESPN.com's divisional rankings, Viloria is ranked No. 2 while fellow titlist Marquez is No. 1. Marquez's 2011 war with Luis Concepcion was fight of the year stuff. A unification clash with Viloria would almost guarantee action.
Sonny Boy Jaro (34-10-5, 24 KOs). Normally, Jaro wouldn't belong anywhere near this conversation, but after sending Wonjongkam to his first defeat since 1996, the journeyman suddenly finds himself holding a title belt. This could be a natural in the Philippines, and even though Viloria would be a big favorite, his habit of dropping fights he shouldn't could lend this an intriguing air.
Milan Melindo (26-0, 10 KOs). Another potentially attractive all-Filipino clash could see Viloria taking on the undefeated rising youngster. Melindo is the No. 1 ranked contender for Viloria's belt, so this match could be the most likely to be made.
Roman Gonzalez (32-0, 27 KOs). This is probably the least likely of Viloria's potential fights, with Gonzalez still campaigning at 108 pounds. But what a mouth-watering challenge it would be. "El Chocolatito" is one of boxing's best-kept secrets, a terrific young fighter with outstanding knockout power. A fight with the veteran Viloria could raise Gonzalez's profile in the United States overnight.


text:
Come to the Ace for Great Deals on the Hottest Products!
Acebeach Company Everett, WA 98208
Customer Service: Please Call: 425-273-6382
Email: email@example.com
Acebeach Company takes pride in offering the best prices on the internet for all our products. We try our best to offer the lowest available prices on hard to find items, same day shipping, and accurate delivery.
We use UPS, and USPS ___________________________________________________________
** Accepting All Major Credit Cards and Paypal **
** All Items are Brand New ** ___________________________________________________________
"Serving you on the web since 2005"
Our contact information
By email:
Business email address (email@example.com is the default)
By standard mail:
Your business name
Street number and name
City, State, Zip code
By phone:
555 555-1212 (between H a.m. and H p.m. time zone)
Shipping Information:
Enter information about how long it takes for orders to be filled from your store. Use a conservative estimate so you set buyer expectations accordingly.
Refund, Returns and Cancellation Policies:
Enter details of your refund, return, or cancellation policies (if any). Provide instructions for when and how buyers can get a refund, return merchandise, or cancel an order. Review the refund policy of other stores to get an idea of the different approaches and then create the policy that works best for your store.
Frequently Asked Questions:
Answer any questions that buyers are likely to have such as how they can check an order's status, how can they contact you if they have immediate questions, or what shipping options your store offers.


text:
Working for AfriSam
These comments by our employees bear testimony to the care we take in looking after our people. We place great importance in health and safety in the working environment, but there are other common themes that run through these testimonials. Care and respect for our people results in our employees having a sense of worth and belonging and a genuine passion for the work they do.
I am driven to be passionate about my work as I work with a group of people who feel the same. The company values are the same as mine and that makes me feel at home. My hard work does not go unnoticed and I always feel like I am a valuable member of my team.
Matshidiso Twala
Sales Consultant
AfriSam is a dynamic company to work for. The work environment is professional and very committed. While this is the case, we make time to play so that when we work, we are able to give our all.
Bradley Herbert
General Manager
I am a contractor based at SSC and I must tell you that I feel like I am part of this family. I work quite closely with AfriSam employees to ensure that we deliver the products in a manner that satisfies the customer. We share the same passion of pleasing the client and feel equally responsible for creating customer value. I am a part of AfriSam and I am proud to be here.
Nondumiso Faku
Klipstone Control Supervisor
This company is a goal driven organisation and that automatically rubs off on me as the employee. I know what I want in life and work hard towards it. My opinion in the work place also counts as I am encouraged to contribute towards decisions that affect me. Take safety for example, I know that I need to take my and the team's safety into consideration all the time and I have a say in how that is done.
Helena Venter
Admin Assistant – Slagment
I am fairly new in AfriSam and compared to my previous experiences, this company is amazing. I feel like I'm working with the best of the best as the people come with a wealth of knowledge which they are not afraid to share. I'm learning all the time and that keeps me on my toes. In the short period I've been here, I am truly comfortable and feel like I've been here forever.
Mishack Tolom
AARM Systems auditor
I am fairly new in the company and my experience so far has been great. I have been given a lot of support and assistance and that has helped me feel confident enough to carry out my duties. The company also values team work and therefore promotes fun activities that allow us to get to know each other well. This makes the work environment very relaxed and we feel like this is our second home.
Brilliant Mbangwa
Credit Controller
As I go about doing my daily chores, I am amazed at how the people here value their customers. In my job, I tend to overhear a lot of the conversations and it is not hard to tell that a lot of effort is put towards pleasing the customer. The people here have welcomed us contractors as a part of the family and treat us well. As a result, I feel like I have a role to play.
Daisy Mathebula
Contractor -Prestige
There's not a day when I get up dreading to come to work. This environment is so light and positive that it does not feel like work. I really look forward to my job all the time as I know that I am treated with respect, even when I make mistakes. This encourages me to aspire to be better at my job. I am learning all the time and that keeps my mind active.
Edward Tshivhidzo
Dispatch Clerk – Roodepoort
The working environment at AfriSam is energetic and positive, always cutting edge. The company is not scared to take well thought out risks. The focus is always on the customer. We are an organisation that is professional in all that we do and pride ourselves in always doing things right the first time.
Ziyaad Vawda
Logistics Planning Manager
I've been working for AfriSam since 1988. It has been a long but wonderful journey. Daily, I travel a long distance just to be here but it's still a pleasure for me to do it. I've had some fun moments, funny moments, sad moments, happy moments, but through them all, I am treated like a valuable individual. This is what makes it all worthwhile.
Janet Gerry
Credit Controller
I left the company for a while and then came back. That, in itself speaks volumes. I am back because I had the opportunity to compare with what's out there. I can say for sure that no other company can compare. In every decision that is made, management makes sure that its effect on me as the employee is well considered. Just looking at the emphasis placed on my safety, I can honestly say that say that I am appreciated. This allows me to do my job with ease and pride. Even when you look at the remuneration, it is well above industry average.
Edson Matshinge
Batcher - Wynberg B Plant


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About the Book
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Adrian Barber
Manchester, England
Adrian Barber is a photographer and film-maker based in the North West of England specialising in social documentary and community arts. Previous funders include SIPA, ACE, Bolton at Home, Regenda Housing, Contour Homes, Oxfam, Bolton Museums and Archives and many more.
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Futuristic Lamp Controlled By Floating Switch Orb
Finally, the Fiat Lux has given me something to replace my adorable koala bear lamp. It's not quite as cute, but the cool factor more than makes up for it. Powered by a magnetic switch, the lamp is on when the switch sphere is floating below it — suspended by magnets. To turn it off, [...more]


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he chemo was causing more harm than good.
That day I made life a changing decision (either way), I told the oncologist I want the chemo to stop and the remainder of my "treatment" to be an opportunity for me to heal myself holistically. She wasn't happy but gave me an appointment for the 23rd May 2012. Saying they will still follow protocol and treat me even if I don't take the chemo. I wondered whether she didn't worry too much because she probably believed I wouldn't be alive on the 23rd May.
Around that time I met some interesting people on facebook who had a lot to say about cannabis oil curing cancer, I did all the research I could do and could only come up with positive things about the plant. The testimonials of people who have been cured were incredible. I can't mention names, but I wrote on the wall of one of the groups that are fighting to legalize cannabis, asking if anyone knew where I could get my hands on some cannabis oil. I already knew about the benefits while on chemo.
A few days later the universe hooked me up with just the right person – and within days I was sorted.
I managed to connect with some people who are taking the legal issue to parliament. These people knew some people who were growing the herb to heal people with cancer. I paid R7200.00 for 6 syringes for the full dose needed to ingest to kill the cancer, which was 6 syringes full. (Depending on the exchange rate, R7200 South African Rands = $900-1000 US Dollars.)
Cannabis is very strong and the idea is to build up the daily dose over time. One dose is a drop on your finger about the size of "half a grain of rice". The syringe is the easiest way to store and produce one drop of oil at a time. I took all 6 syringes, which totalled 18 grams, in 46 days. Most people take about 90 days.
Now, after doing more research, I plan to buy a Vaporizer to get the oil (like Shona Banda) or will juice raw cannabis, which will work out MUCH cheaper.
There are loads of sites about cannabis oil, one of the best is Phoenix Tears, if you are looking for more information on the subject. http://phoenixtears.ca/make-the-medicine
I started my new treatment on the day I walked out the hospital, declaring my "independence". It's been a journey…Mostly hilarious, but some not so funny experiences as well.
I feel strong, brave, invincible…and I'm so loved…that's worth staying for, I would say! [ read more at link]
Lindsey: Cures Colon Cancer With Cannabis in 48 days | Chris Beat Cancer
he chemo was causing more harm than good.
keyboard shortcuts: V vote up article J next comment K previous comment


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APPLE has let another cat out of the bag - well, almost. A preview of Mountain Lion, as Mac OS X 10.8 is called, has been released to software developers so they can update applications in preparation for the release of the public version in about September.
It will be available only from the online Mac App Store - no boxes. Apple's view is that from now on, everything will come from the cloud.
And while Apple likes to keep its secrets, it has told us a good deal about this Mountain Lion - in particular, that it further integrates desktop and mobile devices, apps and services.
''Mac'' has been removed from Mountain Lion's official moniker, making it just OS X. Apple will also provide annual updates through the Mac App Store, thus replacing software updates.
So iCloud, Apple's internet-based communication and storage system, will be everyone's home base and all-round oracle. Anything stored in an iCloud account, from a contact or an email down (or maybe up) to the text of your last will and testament, will be available simultaneously on all your devices - iPad, iPhone, iPod Touch and Mac - wherever you connect to the internet.
MobileMe did that to a limited extent but iCloud, which soon will replace it, takes things much further. It's also free, including five gigabytes of storage.
iCloud arrived with Lion and more than 100 million users have registered with it. Its function will be much extended by Mountain Lion, for which - as for its successors, and presumably also for iOS - Apple will provide annual updates via the Mac App Store. The trend clearly is ultimately to produce one operating system for all Apple devices.
Mountain Lion won't arrive for another seven months but Apple has given us a taste by releasing a public beta of Messages, the replacement of iChat. Messages brings the mobile devices' iMessages system to the Mac. It's fast and free and likely to eat further into SMS traffic volumes on mobile phone networks.
But for many people, the big feature in Mountain Lion will be AirPlay Mirroring. This was introduced to the iPad and other mobile devices to stream music, videos and photos wirelessly to an Apple TV (the second-generation black one) and thus to a HD TV set.


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The Galaxy made it official Tuesday that Brazilian midfielder Marcelo Sarvas has signed with the club on a free transfer from Costa Rican champion Alajuelense.
Sarvas last week told a Costa Rican website that he had agreed to a two-year deal with the Galaxy, choosing it over a three-year offer from Alajuela, and L.A. boss Bruce Arena acknowledged his signing during a media teleconference Monday.
"We've signed that player, and we will in the next day or two get out a release on him," Arena said. "He's a good, experienced, two-way midfielder I think is going to help our team. ...
"He's played against us twice this year [in the CONCACAF Champions League]. Good player. Good passer, experienced, a two-way midfielder. I think he's going to be a good addition."
The agreement is pending a physical exam and receipt of his International Transfer Certificate. No terms were announced.
Sarvas, 30, began his pro career with Corinthians in Sao Paulo and played for clubs in Sweden and Poland before signing last January with Alajuelense, with which he's made 27 appearances in 36 league and CONCACAF Champions League games this year.
He has one more game to go in Costa Rica: Sunday's second leg of the Invierno final at Herediano. The clubs drew, 1-1, in the first leg last weekend in Alajuela.
YOUTH IS SERVED: The academy players the Galaxy are looking to sign to Home Grown Player contracts, a source with knowledge of the situation said, are midfielder Jose Villareal (Inglewood/Leuzinger HS), a U.S. under-23 national team pool player, and defender Javan Torre (Santa Monica/Crossroads HS), who has made a verbal commitment to UCLA. The Galaxy have been pursuing for several months a signature from Villareal, who had a September trial in Belgium with KVC Westerlo. He also has options in Europe.


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Yes I know that its only Thursday but I have decided to remind you today to vote for your favourite BunnyTune. A love song in honour on Val & Tiny's day anybun?
- Current Mood: loved
- Current Music:We're Bonded
( 5 comments — Leave a comment )
( 5 comments — Leave a comment )


text:
Signs and symptoms of Klinefelter syndrome vary widely among males with the disorder. Many boys with Klinefelter syndrome have few noticeable signs, and the condition may go undiagnosed until adulthood. For others, the condition has a noticeable effect on growth or appearance.
Signs and symptoms of Klinefelter syndrome also vary by age.
Signs and symptoms may include:
See a doctor if you or your son has:
Klinefelter syndrome occurs as a result of a random error that causes a male to be born with an extra sex chromosome. It isn't an inherited condition.
Humans have 46 chromosomes, including two sex chromosomes that determine a person's sex. Females have two X sex chromosomes (XX). Males have an X and a Y sex chromosome (XY).
Klinefelter syndrome can be caused by:
Extra copies of genes on the X chromosome can interfere with male sexual development and fertility.
Klinefelter syndrome stems from a random genetic event. The risk of Klinefelter syndrome isn't increased by anything a parent does or doesn't do. For older mothers, the risk is higher but only slightly.
Klinefelter syndrome may increase the risk of:
A number of complications caused by Klinefelter syndrome are related to low testosterone (hypogonadism). Testosterone replacement therapy reduces the risk of certain health problems, especially when therapy is started at the beginning of puberty.
Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below.
Mayo Clinic is a not-for-profit organization and proceeds from Web advertising help support our mission. Mayo Clinic does not endorse any of the third party products and services advertised.
A single copy of these materials may be reprinted for noncommercial personal use only. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.


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China says confident in North Korea's new leader
China Monday voiced confidence in the new leader of its impoverished ally North Korea after his father Kim Jong-il died, promising to support Pyongyang as it enters into a uncertain transition.
We feel incomparably anguished, and offer our deepest condolences to the entire North Korean people, said China's top leaders, in a statement read out on state television's main evening news.
The Chinese people will always cherish his memory, said their message, which called Kim a great leader who was a close friend of China.
We are sure that the North Korean people will abide by Comrade Kim Jong-il's will and unify around the Korean Workers' Party, and under the leadership of Comrade Kim Jong-un turn their anguish into strength, it added.
Impoverished and squeezed by international sanctions for conducting a series of nuclear and missile tests from 2006, North Korea has reached out to Moscow and Beijing for help to fill the gap left by the drying up of South Korean and the U.S. economic assistance.
Over the past 18 months, Kim, who in the past rarely travelled abroad, visited China four times and in August made his first trip to Russia in nearly a decade.
We are convinced that with the shared efforts of the two sides, the friendship between the parties, governments and peoples of China and the North Korea will be strengthened and developed, said the statement. The Chinese people will always stand beside the North Korean people.
Kim's visits were mainly aimed at winning economic support, and raised speculation he may finally be opening one of the world's most closed economies.
During Kim's China visit in May, the two sides vowed that their alliance, sealed in blood, would pass on to their successors.
For China, its much smaller and poorer neighbor is both a buffer and a burden.
China sees North Korea as a strategic barrier against the United States and its regional allies. But that barrier comes with an economic and diplomatic price.
As the North's ties with South Korea and much of the outside world have soured, Kim has leaned more on ally Beijing for support, which has cost China both in economic aid and in strains with South Korea and other nations alarmed by North Korea's nuclear weapons development and military brinkmanship.
China has sought to draw North Korea closer with incentives, and bilateral trade hit $3.1 billion in the first seven months of 2011, an 87 percent increase from the same period last year, according to Chinese customs statistics. Growth was propelled by a 169.2 percent jump in the value of Chinese imports.
Beijing has shored up its support for Pyongyang in the past two years, despite regional tension over North Korea's actions, including nuclear weapon tests in 2006 and 2009 that drew U.N. sanctions backed by China.
(Editing by Jonathan Thatcher)


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Slideshow: More Gin Cocktails
Slideshow: More Classic Cocktails
- Servings: Makes 1 drink
- 2 ounces gin
- 3/8 ounce maraschino liqueur
- 3/4 ounce fresh lemon juice
- 3/8 ounce violet liqueur
- 1 marasca cherry
How to make this recipe
Fill a cocktail shaker with ice. Add all of the ingredients and shake until chilled. Strain the drink into a coupe glass and garnish with a marasca cherry.
Contributed By Eric Alperin Photo © Dave Lauridsen Published February 2010


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Now, reasonable yoga teachers can and do disagree about what constitutes a Platonic perfect Bow.
My Platonic ideal is the hole-in-the-wall seafood joint, Swan Oyster Depot.
Will and Diane really do represent a Platonic ideal of partnership.
He wants his audience to wake up from their sleep, emerge from their Platonic cave, and see the world as it truly is.
But when pressed on the nature of their relationship—which Stiviano has characterized as Platonic—Sterling clammed up.
Among them is very probably included the Platonic Parmenides itself, distinguished as it is for extreme subtlety.
We also find the Platonic division into appetitive, spirited and rational.
Doctrine of the Sophistês — contradicts that of other Platonic dialogues.
The Menexenus has more the character of a rhetorical exercise than any other of the Platonic works.
Not even in the case of an aged hypocrite who probably posed as the Platonic friend?
1530s, "of or pertaining to Greek philosopher Plato" (429 B.C.E.-c.347 B.C.E.), from Latin Platonicus, from Greek Platonikos. The name is Greek Platon, properly "broad-shouldered" (from platys "broad;" see plaice (n.)). His original name was Aristocles. The meaning "love free of sensual desire" (1630s), which the word usually carries nowadays, is a Renaissance notion; it is based on Plato's writings in "Symposium" about the kind of interest Socrates took in young men, which originally had no reference to women. Related: Platonically.


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Not just a construction boom! Schools in Dubai to grow by 70% in less than a decade
Based on the education sector's historical growth over the last 10 years, 110 new schools are expected to enter the market in the next seven years
The growing demand for education in Dubai will increase the number of schools by 70 per cent in less than a decade, the Knowledge and Human Development Authority (KHDA) has predicted.
Speaking at Destination Dubai 2020 conference on Tuesday, Kalthoom Al Beloushi, director of institutional development at KHDA, said that based on the education sector's historical growth over the last 10 years, 110 new schools are expected to enter the market in the next seven years to accommodate 130,000 students.
KHDA is a regulatory authority that is responsible for the growth, direction and quality of private education and learning in Dubai. It supports the improvement of schools, universities, training institutes and other human resource sectors.
Al Beloushi said the entry of new schools is expected to slow down the growth of tuition fees in Dubai. A number of expatriates, which make up the majority of the population, send their children to private schools in the country and are finding that the high education cost is eating up a major portion of the household budget. A research by HSBC showed that the UAE is the fourth most expensive country for foreigners to study and live in.
More options
"The entry of new schools will somehow slow down the increases or shake up the market, because that would mean there will be more options for people to choose from," Al Beloushi said.
The new schools will mainly be operated for profit, although the KHDA is also encouraging the entry of non-profit educational institutions. Dubai is home to 153 private schools offering programmes to 225,000 students across 15 different curricula. Private schools cater to the majority of Dubai's population, about 88 per cent.
Al Beloushi said there is a rising investor interest to tap Dubai's fast-growing market for education. "We see investors on a daily basis. A lot of people are interested in opening early learning centres as well as higher education and training institutes. There is a high demand for education. Dubai as a destination is a nice place to be in. It's safe and you have everything around you," he added.
Top Headlines
- Al Tayer bucks the US department store trend with Bloomingdale's Kuwait opening
- Gulf Islamic banks set to outperform conventional banks for second year: Moody's
- Jordan secures EU finance for socioeconomic and environmental programs
- Same-day service deliveries in GCC an untapped market: Wing CEO
- Will terror attacks damper Arabs' appetite for European holidays?
- al mawakeb schools to increase fees by just 8 per cent
- Saudi hospitality sector to create 2.3 million jobs by 2020
- House of Patel's US$25 million 'Natasha Riverdale' project - 75 percent sold out in less than two months since its UAE launch
- Starck and Hitchcox Design Company Refuses to Settle for 'Anything Less Than the Best'
- Ground Reality rather than Speculation to Drive Growth in Middle East Construction Sector


text:
Welcome to UNC Dining Services... where "We Feed The Bears!"
Summer 2017 is here!!
We're pretty excited that the dining rooms are open for the summer!! And don't forget... select Retail Dining locations are open now!!
- Summer Hours of Operation
- Summer Meal Plans
- Summer Weekly Dining Room Menus
- Purchase Meal Plans and Dining Dollars
Navigating through life can be a little challenging at times... making time for healthy, tasty, and nutritious meals shouldn't have to be!
Dining Room Options
Students who choose to carry a meal plan have the convenience of enjoying meals at any of our dining rooms on campus... including the UC Food Court and Bears Bistro.
Our dining rooms offer a large variety of foods, including fresh fruits and veggies, vegetarian and vegan options, allergen-free options... and Holmes Dining Hall & Tobey-Kendel Dining Room are both "all you care to eat" locations that have a gourmet salad bar available every day. There are to-go options available as well if you don't have time to sit down and eat with us.
Hungry and don't know which dining room to try? We have LOTS of choices. Dining room menus are posted online every Friday, so take a look at what's being served this week. You're not required to eat at any one location, so why don't you try them all!? Check out the Dining Room hours of operation here.
Dining Dollars
In a rush and just want to stop by for a cup of coffee and a bagel? Why don't you use your Dining Dollars??! Dining Dollars are very handy to have loaded onto your UNC Card, and we have lots of different locations where they are accepted. Check out the Retail Dining hours of operation here.
Registered Dietitian Available
Do you have any specific dietary issues that you need us to know about? We can usually accommodate most requests, but we recommend you speak with our Registered Dietitian about it first... he will be able to tell you what we can offer. You can contact Matthew Doyle, RDN, at 970-351-1961 or email@example.com.
Can't find what you're looking for? Have more questions? No problem... contact Dining Services at 970-351-2652, email us at email@example.com, or stop by Tobey-Kendel Hall (room 120) and ask us in person! "We Feed The Bears!"


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Shakespeare Under the Stars 2008: Much Ado About Nothing
Presented by Austin Shakespeare at Zilker Park
May 1 - May 25, 2008
The 'Merry War' of the sexes erupts in Austin Shakespeare's production of Much Ado About Nothing, to the accompaniment of music & dance. Starring Austin's Babs George and Matthew Radford (Actor of the London Stage. Check out these great Show Photos.
Much Ado launches the 23rd annual presentation of a beloved Austin favorite, 'Shakespeare Under the Stars.' Artistic director, Ann Ciccolella, brings a delightful fresh perspective to this Shakespearean comedy favorite.
2100 Barton Springs Road
Austin, TX 78704
Admission Info:
Free Admission
General Day and Time Info:
Thursday-Sunday 8:00pm
Accessibility Information: Currently, no accessibility information is available for this event.
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text:
must be a truck,car,or van modle for 1960 to 1978
Members: 85
Latest Activity: Aug 13, 2013
Started by Robert Bernier Jan 8, 2011.
Started by Robert Wimer Nov 9, 2009.
Started by tucker. Last reply by Goodsons14 May 22, 2009.
I need a 78 Ford Ranchero GT gas tank with the float already in it . THANKS call Jerry at 731-772-9514 Brownsville Tn.
this is my 1966 ford f100 it one of kide truck i have


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Woods Hole Oceanographic Institution
Weifu Guo
Front Page
Curriculum Vitae (external file)
Isotope fractionations associated with microbial nitrate reduction
Clumped isotope calibration in aragonites
MIF associated with SO2 UV photolysis
Clumped isotope in speleothems: Natural observations
Sulfur isotope of VOSC
Stable isotope cosmochemistry
Clumped isotope fractionation associated phosphoric acid digestion
Methods of clumped isotope analyses
Clumped isotope of stratospheric CO2
PhD Dissertation
Aqueous alteration of CM chondrites
Carbonate clumped isotope thermometry
Guo, W.
, Granger, J., Sigman, D. M. ,
Nitrate isotope fractionation during biological nitrate reduction: Insights from first principles theoretical modeling
, Eos Trans. AGU, Fall Meet. Suppl. Abstract PP34A-08, 2010
Coupled fractionations of N and O isotopes during biological nitrate reduction provide important constraints on the marine nitrogen cycle at present and in the geologic past. Recent laboratory experiments with mono-cultures of nitrate-assimilative algae and plankton, and denitrifying bacteria demonstrate that N and O isotopic compositions of the residual nitrate co-vary linearly with a constant ratio (i.e., Δδ18O: Δδ15N) of ~1 or ~0.6 [1]. These systematic variations have been inferred to derive from the kinetic isotope fractionations associated with nitrate reductases. The isotope fractionation mechanisms at the enzymatic level, however, remain elusive. Here we present models of isotope fractionations accompanying the nitrate reduction (NO3-→NO2-) by three functional types of nitrate reductases, using techniques from ab initio, transition state and statistical thermodynamic theory.
We consider three types of nitrate reductases: eukNR (eukaryotic assimilatory nitrate reductase), NAR (prokaryotic respiratory nitrate reductase) and Nap (prokaryotic periplasmic nitrate reductase). All are penta- or hexa-coordinated molybdo-enzymes, but bear considerable differences in protein geometry among functional types. Our models, based on the simplified structures of their active sites, predict N and O isotope effects (15ɛ and 18ɛ) ranging from 32.7 to 36.6‰ and from 33.5 to 34.8‰, respectively, at 300K with 18ɛ:15ɛ ratios of 0.9-1.1. The predicted amplitudes of N and O isotope fractionations are in the range measured for eukNR in vitro (~27‰, Karsh et al. in prep), and also correspond to the upper amplitudes observed for denitrifiers in vivo (~25‰, [1]). Moreover, the computed 18ɛ:15ɛ ratios corroborate the consistent relationships of ~1 observed experimentally for eukNR and the respiratory NAR. These findings indicate the enzymatic reduction is likely the rate-limiting step in most biological nitrate reductions. In addition, the predicted similarity of 18ɛ:15ɛ ratios among different nitrate reductases suggests that the nitrate isotope fractionations by nitrate reductases are governed by the kinetics of the O-N bond cleavage, which incurs negligible differences from variations in surrounding moieties at the active sites. However, our model similarly predicts a 15ɛ of 36.6‰ and 18ɛ:15ɛ of 0.9 for the auxiliary Nap, although it exhibits a 15ɛ of ~15‰ and 18ɛ:15ɛ of ~0.6 in vivo [1]. This discrepancy is suspected to arise from slower binding and release of NO3- from Nap, which could be partially rate-determining in this enzymatic catalysis, or from the assumptions of our modeled enzyme structures.
By extending our above models to include the multiply-substituted (clumped) isotopologues, we predict that isotope fractionations during biological nitrate reduction decrease the proportion of 15N-18O bonds in the residual nitrate relative to their expected equilibrium abundances (~0.02‰ decrease for every 1‰ kinetic enrichment in nitrate δ15N). Future quantification of 15N-18O clumped isotope anomalies in natural nitrate may provide additional constraints on the nitrogen cycle in the ocean.
Woods Hole Oceanographic Institution
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Senior Enlisted Leader
Master Chief Sermeno was born in El Paso, Texas. He graduated from Onate High School in 1999 and entered the United States Navy in June of that same year. He completed recruit basic training at Recruit Training Center Great Lakes, Illinois followed by Basic Radioman "A" School. His first assignment was USS ESSEX (LHD-2) at San Diego, California where he participated in the Navy's first Large Deck hull swap to USS BELLEAU WOOD (LHA-3). During his tour onboard USS BELLEAU WOOD he qualified as Enlisted Surface Warfare, Enlisted Aviation Warfare and Communications Watch Officer. In February 2005, he reported to NCTAMS EURCENT at Naples, Italy where he participated in the decommissioning to NCTS Naples. During his tour at NCTS Naples he qualified as FTOC Watch Officer. In March of 2008, he reported to USS MAKIN ISLAND (LHD-8) where he was part of the pre-commissioning crew. During his tour onboard USS MAKIN ISLAND he assisted in establishing and qualified in Enlisted Information Dominance Warfare Program, Combat Systems Training Teams and deployed on the maiden voyage 2009 and MAKIN ISLAND's first deployment. It was onboard USS MAKIN ISLAND where he was selected to Chief Petty Officer. In December 2012, he reported onboard USS BLUE RIDGE, during his tour he qualified as Damage Control Training Team, Anti-Terrorism Training Team and managed the 3M program. Master Chief Sermeno assumed the duties as the Senior Enlisted Leader to OIC NCTAMS LANT det Jacksonville in Feb 2016. His personal awards include: Navy and Marine Corps Commendation Medals, Navy and Marine Corps Achievement Medals, Good Conduct Medals and various unit and campaign awards. He is authorized to wear the Enlisted Surface Warfare Specialist (SW), Enlisted Information Dominance Warfare Specialist and Enlisted Aviation Warfare Specialist (AW).
US Navy Recruiting | No Fear Act Data | FOIA
US Navy | US Marine Corps | Navy Reserves
US Navy FAQ | USA.gov | Section 508/Accessibility


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Michigan freshman Mitch McGary was cast into the recruiting spotlight over a year ago with his strong play and physical gifts. What separates him is his no pain, no gain mentality and the nose for the ball that allowed him to corral 10 rebounds in 20 minutes against Saginaw Valley State Monday night, and 9 boards in 17 minutes against Northern Michigan.
"I think everybody has really big expectations but I'm just trying to go out there and have fun and win the game," said McGary. "My main job is just to get rebounds and thats what I like doing. I'm happy not scoring a point and getting rebounds."
McGary's aggressiveness and energy is obvious. So much so that he found himself in some first half foul trouble, accumulating three in the first 20 minutes of play.
"He's done a better job in practice cause we're pretty sure in practice we probably call fouls that aren't fouls just to make sure he knows," said coach John Beilein. "And he's really done a better job than --- Jon Horford and Jordan Morgan continue to have habits of fouling. I think he's done a pretty good job."
"He'll get better at it but his intensity, we're not going to turn that down," added Beilein. "He's got to keep playing hard but smart."
McGary may not be concerning himself too much with his offensive game and that development but the Chesterton, Indiana native showed flashes of what he's capable of.
In the first half McGary gained position in the mid-post, turned to his left between two defenders and laid one in off the glass.
In the second half, McGary used his defensive instincts for an easy bucket, intercepted an entry pass at the top of the key, chasing the deflected ball down and picking it up just in time for a windmill right handed slam that had the bench and fans at Crisler Center buzzing.
To watch video of McGary after the win over SVSU, press play below.


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Field Operations · District 4 Home Page
Welcome to the District 4 web page. This district covers the seven Eastern Washington counties of Adams, Ferry, Lincoln, Pend Oreille, Spokane, Stevens, and Whitman. The district headquarters is located in Spokane and detachment offices are located in Colfax, Colville, and Ritzville.
District 4 employees are assigned to traffic law enforcement, criminal investigations, auto theft, narcotics investigations, commercial vehicle enforcement, vehicle inspections, communications, fire protection, and support services. A crime laboratory is also located within district confines.
Captain Otis is honored to serve the citizens of this state as the District 4 Commander. "I am proud of the efforts of the men and women of District 4. Every day we strive to enhance the safety and security of our state and provide the best in public safety services."
Goals & Objectives
Focus Statement:
District 4 and its employees are dedicated to achieving the goals and objectives of the Washington State Patrol. District 4 personnel serve the citizens of seven counties in Eastern Washington through traffic law enforcement, quality investigations, criminal interdiction, motorist assists and terrorism prevention.
Address Directory
Headquarters & Communications:
6403 W Rowand Rd, Spokane, WA 99224-5300 - (509) 227-6566
Eastbound travelers, take Interstate 90 east to Spokane, Exit 276 (Geiger). At the end of the ramp, turn left, crossing over I-90 to the four-way stop. Turn right, then turn right again on Rowand Road. The Spokane complex is on the right, across from Rowand Machinery. For Westbound travelers, turn right at the four-way stop off Exit 276 (Geiger) and then right again on Rowand Road.
Colfax - 840 W Fairview St, Colfax, WA 99111-9515 (509) 397-3600
Spokane Port of Entry:
Spokane Port of Entry -Westbound I-90, Milepost 298, (509) 838-9400
Vehicle Inspections:
Call (509) 227-6630 for correct times and locations.
Problem Oriented Public Safety
The State Patrol's style of community policing is called Problem Oriented Public Safety, or POPS. The foundation of POPS is based on a philosophy of taking the concerns of the motoring public by addressing persistent problems. When a problem is identified by a citizen, trooper, or anyone with a concern, the POPS trooper works with other agencies and groups to develop the best achievable solution to address the origin of the problem. Solutions to various problems may range from simply educating the public to major construction projects.
POPS Coordinator:
Lieutenant Chuck Arnold
Resource Links & Travel Information
Please note that some of the documents provided on this page are available in Adobe® PDF format only and will require the Adobe® Reader in order to view or print them from your Web browser.
District Information


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Get an overview of this hotel3.5-star hotel, walk to Senado Square
Popular property highlights
Situated in a shopping district, this hotel is within a 10-minute walk of Cineteatro Macau, Senado Square, and Leal Senado. Ruins of St. Paul's Cathedral and Fortaleza do Monte are also within 15 minutes.
Hotel Features
A restaurant, a coffee shop/café, and 24-hour room service are available at this hotel. WiFi in public areas is free. Additionally, a business center, meeting rooms, and concierge services are onsite.
Room Amenities
All 240 rooms provide free WiFi, 24-hour room service, and cable TV. Guests will also find minibars, free bottled water, and hair dryers.Information missing or incorrect? Tell us!Opens in a new window
Hotel Sintra
Hotel Amenities
Hotel Amenities
The hotel offers a restaurant and a coffee shop/café. Public areas are equipped with complimentary wireless Internet access. This 3.5-star property offers access to a business center and meeting rooms. This business-friendly hotel also offers tour/ticket assistance, concierge services, and laundry facilities.
Hotel Sintra has designated areas for smoking.
- Total number of rooms - 240
- Concierge services
- Breakfast available (surcharge)
- Business center
- Coffee shop or café
- Safe-deposit box at front desk
- Dry cleaning/laundry service
- Elevator/lift
- Free ferry terminal shuttle
- Designated smoking areas
- Tours/ticket assistance
- Free WiFi
- Laundry facilities
- Meeting rooms
- Luggage storage
- Restaurant
- Shopping on site
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Room Amenities
- Air conditioning
- Minibar
- Hair dryer
- Free bottled water
- Daily housekeeping
- Private bathroom
- Free toiletries
- Slippers
- Shower/tub combination
- Desk
- Iron/ironing board
- In-room safe
- Cable TV service
- Free WiFi
- Room service (24 hours)
Where to Eat
Buffet breakfasts are available for a surcharge and are served each morning between 7 AM and 11 AM.
Sintra - This restaurant specializes in Chinese cuisine and serves breakfast, lunch, and dinner. Guests can enjoy drinks at the bar.
24-hour room service is available.
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
Hotel Policies
Check-in time starts at 3 PM
Minimum check-in age is 18
Check-out time is noon
Payment types
Children and extra beds
- Children are welcome.
- Rollaway/extra beds are not available.
- Cribs (infant beds) are not available.
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on property policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- No onsite parking is available.
No rollaway/extra beds available
No cribs (infant beds) available
Optional extras
- Fee for buffet breakfast: HKD 130 for adults and HKD 130 for children (approximately)
Hotel Name
- Hotel Sintra
- Hotel Sintra Macau
- Sintra Hotel
- Sintra Macau
- Sintra Hotel Macau


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SlimLipo Overview
The Slim in SlimLipo is an acronym that stands for "Selective Laser-Induced Melting". The manufacturer claims SlimLipo's laser wavelength melts fat 3-5 times better than SmartLipo. The procedure is also designed to reduce the side effects and recovery time associated with traditional liposuction. Typical areas for fat reduction and skin tightening include the stomach, hips, thighs, arms, neck and chin. SlimLipo is sometimes referred to as Lifesculpt.
Was this guide helpful? Thanks for your feedback


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The MLB Network on Monday announced the hiring of three studio hosts and reporters, including Alanna Rizzo, who used to work as a weekend sports anchor and reporter for WISC-TV (Channel 3) in Madison.
Rizzo joined the MLB Network from ROOT Sports Rocky Mountain, where she co-hosted "Rockies All Access," reported on Colorado Rockies telecasts, served as a sideline reporter for the telecasts of University of Colorado basketball games, University of Denver basketball and hockey, as well as high school football games.
Rizzo is a native of Colorado, and has both a B.A. and M.A. from the University of Colorado in broadcast journalism.
MLB Network also hired Lauren Shehadi, formerly of CBSSports.com and CBS Sports Network, and Scott Braun, formerly of ESPN and CBS Sports Network.
Read more at the Milwaukee Journal Sentinel where this story was originally published.


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Hundreds celebrated the 50th anniversary of a St Paul's Cray church with a memorable fun day.
The event at St Barnabus Church in Rushet Road featured bouncy castles, a barbeque, cream tea and lots of stalls and games including a coconut shy and beat the goalie.
A pony also made an appearance, on which children could ride.
Mary Thomson, who has been going to the church for 40 years and organised the event, said: "This is just one of the things we have going on to celebrate 50 years.
"It was lovely - that day had started off with a huge downpour but after that it warmed up - it was too warm if anything."


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It's been a couple of weeks since we had our annual Cranky Concierge staff meeting, which means I can now look back to judge its effectiveness.
Because everyone works remotely in the company, I like to bring some of our core people together once a year for a few days to bond and to think strategically about our operations.
It went pretty well this year. I tried to get us a meeting room at a local hotel, but no one had a small room available for a decent price. So, we did what a lot of small businesses do: We improvised. We took over a corner of the lobby at the hotel where our visiting employees were staying. This proved to be a great (and free) space for the four of us since there were couches and tables that were perfect for collaboration. Oh, and the Wi-Fi was fast and free of charge.
As predicted, we couldn't spend whole workdays discussing long-term strategy, because we had a lot of clients to assist. But in the end, we spent half the day working together, which I think was enough time.
We devoted our first session to talking about business problems and figuring out how to fix them. Some of these were small, such as updating the contact information we have for some vendors, so that the right people within our organization get contacted when there are problems. Simple and stupid, I know. But we also talked about more substantive things, such as a concern that our change fees are too low when it comes to award travel. We worked through ways to address that.
We spent our second session focusing on ways to grow the business. I don't want to get too specific in this blog post, but we identified some opportunities to grow our client base in industries that generate a lot of travel and aren't as price-sensitive as our current markets. We also talked about new services we might offer, including an option for helping clients figure out how to earn more frequent flier miles (not just spend them).
By the end of the staff meeting, I had a long list of things to follow up on, and that's what I had hoped for. The ideas and solutions that surfaced should help guide us over the next few months.
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Lighting & Mobile Electronics (I.C.E.)
Xenon lighting, HID kits, fog lights, BMW head units, navigation, speakers, subwoofers, In Car Electronics (I.C.E.), carputers, DDEs, angle eyes, halos, LED tail lights, interior lighting, etc.
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Registered User
Join Date: Jan 2004
Location: SAN JOSE
Posts: 129
My Ride: 2001 330i
diamond audio12'' macdaddy and chrome ppi amp
diamond audio macdaddy 12'' sub in custom box (their patented sealed/ported box covered in dark grey carpet)
precision power ppi1400 - one channel 400w amp at 4 ohm that i run at 2 ohm and i think it puts out 800w. i'm next to positive it is one ohm stable at which point it produces 1200w. the amp is chrome and i think it's some sort of limited edition which is besides the point because it's show quality power and looks. for sale for best offer.
(looks like this guys http://cgi.ebay.com/ws/eBayISAPI.dll...category=18796 )
these two together are one of the best sub/amp combos i've ever heard. everyone always thought i had 3 12's.
i may also have an alpine flex5 amp for sale for best offer. (4channel at 75w per channel +1 channel at 180w)
this next part is just what www.diamondaudio.com said about this sub
MacDaddy HEX Subwoofers - Maximum woof.
In the world of high-end automotive bass reproduction, it's all about power, control, and displacement (diameter X excursion). With a total of over 50 years of pro-sound experience (including touring with the most famous artists in Rock) the engineers at Diamond Audio know bass. They have synthesized the latest in CAD engineering and space age composites (quite literally) into massive amounts of controlled cone travel and power handling in a small box design. The result is a new reference in LOW. Power, control, efficiency, clarity. Make no mistake, this has no equal - This is the"MacDaddy".
MacDaddy Subwoofers feature:
· Proprietary Hexacone Technology - Backed by a thin glass fiber shell. Manufactured in Germany, internationally patented.
· Huge 3-Inch Diameter Voice Coil - Heavy gauge pure copper wire on a 3-inch vented aluminum former handles all the power you've got. Efficient 4-layer design turns that power into SPL.
· 2-Inch Peak-to-Peak X-Max! - Our Extended Pole Piece architecture (unique in mobile audio) creates a uniformly symmetrical magnetic field above and below the top plate for improved dynamic linearity. Dramatically extends usable X-max.
· Santoprene Rubber Surrounds - Long excursion in all temperature extremes for superior bass response. Excellent damping characteristics. Impervious to sun and moisture.
· Custom-Cast Aluminum Alloy Frames - Antimagnetic, non resonant, very ridged. The perfect environment to maintain our precision driver geometries. Assures linear response after installation and for a lifetime. Laboratory treated to a weatherproof, electrostatically applied, 3-layer Diamond Dust finish.
· Dual Mirror-Image Flat Progressive Spiders - Two spiders (as no single spider made can take the power) insures precise voice coil centering and accurate dynamic linearity in the face of tremendous power applications. Mirror-image configuration cancels any minor push-pull non-linearity.
· "Intercooled" Motor - The high efficiency motor assembly is dynamically cooled via dual radiused, aero-vented pole. This design effectively pumps hot air out, and cool air.
· One-Piece Pole/Backplate - Magnetically and thermally efficient for highest output and power handling.
· 4 and 8 Ohm Impedance - Affords complete flexibility of system design to maximize amp power and damping.
just sold my 03 zx6r 636, fully done up integra, and my life to get a white 330i bmw.
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Related Topics:
I am trying to find out the size of the aqueous cleaning market for a presentation. Do you know an approximate figure? By the way, your "Practical Guide to Industrial Metal Cleaning" has been a great training tool. B.B.
Thanks for the feedback, it is always appreciated. I tried to do some digging to come up with an answer to your question and was not able to find much. I forwarded your question to a company that should know more than I do about market size. Jeff Beard is North American Sales Manager for Petroferm. They are in the chemicals formulating/sales end of the business as well as contract cleaning. His response to your question is as follows (I guess I don't feel that bad that I couldn't answer it):
In regards to your question, "How big is the aqueous cleaning market?" Here's where we are…
We have thought about it, wondered about it, talked about it, pontificated about it and all theories lead back to the same answer. There is no published answer and as near as we can tell, there is no way to come up with a good answer quickly. I am not sure speculation could even get us close. Here is why this is so hard to pin down.
This market is extremely fragmented. There are large companies selling aqueous products for a variety of uses and markets. There is an aqueous fluid for virtually every application imaginable, from floors to lens. For every one "large" company there are what… 20, 50, 100 "smaller mom and pop"-type companies making very good, effective aqueous cleaners for customers in their specific city, state, region. Virtually all of these companies are private, so there is no sharing of sales information or volumes produced/sold.
I decided to open up the Indianapolis Yellow Pages. Inside I found 30 chemical suppliers. Now multiply that by every city in the United States and you quickly see the problem to developing an educated answer to your question. –Jeff


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Amazing footage of attempts to rescue ship stranded in Antarctic ice
South Korean vessel reaches Russian ship and its 32 crew members — who had been stuck in thick sea ice for 10 days.
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The 'hole' of Lake Berryessa is a life-saver
What looks like a terrifying hole to the underworld is much more benign.
What's so dangerous about Jacob's Well?
A central Texas getaway lures daredevils and those simply wanting to cool off.
Antarctica's 'lost meteorites'
Antarctica is oddly barren of iron-based meteorites. What could have happened to them?
The mystery of Devil's Kettle Falls
2 waterfalls send half of a river on its way to Lake Superior. Where did the other half go?
Why are humpback whales rescuing orcas?
Scientists are baffled at this seemingly altruistic behavior.


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Home > Institut Curie > Information Area > Press Area
Press area
Welcome to the Institut Curie press aera.
This is the place where you will find scientific, medical, institutional and promotional news, press releases and press kits, publications, information about the Institut Curie, as well as a direct link to the photo library.
- Press releases and kits
- Periodical publications
Institut Curie


text:
by Dejan Dizdar
Related Editions
Ebook, Apple iPad format
About the Book
A collection of more than 150 fine art nudes, taken in the deserts of Israel, South Africa and Namibia by Dejan Dizdar, EFIAP.
Features & Details
- Category Fine Art Photography
Standard Landscape, 10×8 in, 25×20 cm
160 Pages
- Hardcover, Dust Jacket: 9781320025935
- Softcover: 9781320025928
- Hardcover, ImageWrap: 9781320025942
- Publish Date Nov 13, 2010
- Language English
- Tags beauty, body, landscape, fine art, female, photo, erotic, israel, woman, photography, desert, nude, naked
About the Creator
Born in Belgrade, Yugoslavia where I studied music and electrical engineering. From late 70's till now exhibited worldwide at close to 400 group exhibitions winning prizes and awards and held 25 one-man shows in Serbia, Croatia, Bosnia, Israel, South Africa and Russia. Photographs published in numerous magazines and books and sold to collectors in places as remote as New Caledonia or Tasmania. Teaching the Art of Nude in a photographic studio in Tel Aviv and in subject-dedicated workshops. Holding the EFIAP (Excellence, Federation Internationale d'Art Photographique) title. Currently living in Israel, with frequent visits to Europe. In 2010 established the International Photographic Art Center in Serbia.
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3 Comments
Wayne M. Hope I just received my copy of your "Mirages" book and I'm very happy with it. Lots of great photos, but if you want to know my favs, they are pp 23, 48, 73, 89, 97, 113, and 157. The models are all quite lovely!
lecriveur Stunning as ever. So glad to see that you've made this book. I have a couple of your prints that I picked up on eBay.
Best Regards,
Wayne M. Hope Very nice work!


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All class groups
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Voters and designers. Read me.
About the sumbitted designs and the election of a design.
Javier Rubacha
2009-12-18 16:25:44
2009-12-19 03:11:11
1. Voters and designers. Read me.
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Javier Rubacha - 2009-12-18 18:49:47
While browsing through the designs that where sumbited, I noticed that some of them have bugs, have a broken structure in some (or all) of the preview pages, or have compatibilty problems with different browsers and resolutions.
I think that these designs are not complete and it's not fair for the authors that invested time and effort making a design that doesn't break in the different type of previews and is compatible with the most common browsers.
This seems that some designs where submited as a "preview" of how the site will look if they win the contest, leaving structure and compatibilty problems for later.
I read in another post that there wasn't enough time to check all the designs in all types of pages and in different browsers, so, the approval or rejection of the designs was based on the default type of page (is this correct?).
I think that this information should have been supplied when the submission period started, so authors could decide if they wanted to invest their time in a more good looking design or more solid, bug free and compatible design.
If you have already voted, I want to know if you previewed the theme in different types of pages and paid attention to structure thing or you just thought that "ok, I really like this one and don't care about bugs, will be fixed in the future".
If you are about to vote, take your time to see all types of preview, and in my opinion, this thing of an uncomplete design should also be taken into account (valuing the work required for that). Again, that is my opinion.
If you have subbmited a design proposal I want to know if you had a similar feeling about this topic.
Would like to read some feedback.
2. Re: Voters and designers. Read me.
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Roberto Aleman - 2009-12-19 01:59:38 -
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i agree with you, i sent a proposal compatible with all browser and others at the elefant pretty have many many bugs, this not is correct..the designs with problems not |deberian| are in the competence, neither must be accepted that show a double design, the one which has in the Web site www.phpclasses.org and the one which places in your web
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Manuel Lemos - 2009-12-19 03:11:11 -
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from Javier Rubacha
The problem is not that there was no time to review, but rather that there is an infinite number of combinations of site resolutions, types of pages, types of users to check for every design.
Even if it was feasible to review all proposals in that aspect, probably no design would pass because it is not hard to find a combination that a given proposal would not look good.
The site imposed no requirements on that sense. Instead, the voters will be able to vote on the most appealing theme, and if the winner still have issues that were not fixed, the author can fix them before using the theme in the site.
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Grandparent visitation case appealed to ND Supreme Court
GRAND FORKS — A couple here who were sued by the man's parents for visitation with the grandchildren is appealing the case to the state Supreme Court.
That's after a judge confirmed his ruling that Cory Bjerke and his longtime partner, Naomi Sterf, must allow their 16-year-old to visit her grandparents any time she wishes, and must allow the couple's other two younger children to see Bjerke's parents.
State law says grandparents may be given visitation, as long as it's in the children's best interests and doesn't interfere with the parent-child relationship.
Bjerke and Sterf argue that the 16-year-old's unfettered visitation rights laid out in the order by Grand Forks County District Court Judge Lawrence Jahnke do interfere with their parent-child relationship.
They argue that by giving their teenage daughter free rein to leave for her grandparents' home anytime she likes, the teen has an opportunity to get out of discipline, chores or other sources of disagreement with her parents, thereby undermining their parental authority.
The elder Bjerkes asked the court to hold their son and his partner in contempt, saying they hadn't been following Jahnke's instructions that guaranteed the grandparents would spend many holidays with the three children.
The parents admitted at a Sept. 10 hearing that they hadn't followed the judge's order but reiterated their belief that it interfered with their parenting rights.That hearing drew about 20 people who demonstrated in front of the Grand Forks courthouse in protest of the judge's order.
Jahnke ruled Sept. 25 that he would defer holding Bjerke and Sterf in contempt for failing to follow his order. However, he said in his ruling that Bjerke and Sterf had not shown that the visitation the 16-year-old was granted had actually created any problems with their parenting.
The judge wrote that he hoped the bad feeling between the two sets of adults could be set aside, especially as holidays approached.
"It's time for the Respondents and Petitioners, for the sake of their children and grandchildren, to once again attempt to re-establish a civil dialogue with one another. They can't expect the court to repair their fractured relationship," Jahnke wrote. "Only they themselves can do it."
Bjerke and Sterf declined to comment for this story, as did the elder Bjerkes.
No date has been set for the case to be heard by the state Supreme Court.