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- Take the Blood Disorders Quiz
- Patient Comments: Polycythemia (High Red Blood Cell Count) - Cause
- Patient Comments: Polycythemia - Experience
- Patient Comments: Polycythemia - Symptoms
- Patient Comments: Polycythemia - Treatment
- Find a local Hematologist in your town
- Polycythemia facts
- What is polycythemia?
- What are normal ranges of hematocrit, red cell counts, and hemoglobin?
- What causes polycythemia?
- What are the causes of primary polycythemia?
- What are the common causes of secondary polycythemia?
- Can other sources of erythropoietin (EPO) cause polycythemia?
- What is relative polycythemia?
- What are the risk factors for polycythemia?
- What is stress polycythemia?
- What are the symptoms of polycythemia?
- When should I see a doctor about polycythemia?
- How is polycythemia diagnosed?
- What is the treatment for polycythemia?
- What are the complications of polycythemia?
- Can polycythemia be prevented?
- What is the outlook (prognosis) for polycythemia?
Quick GuideLow Testosterone (Low T) Treatments
What are normal ranges of hematocrit, red cell counts, and hemoglobin?
- Hematocrit is the ratio of the volume of red cells to the volume of whole blood. The normal range for hematocrit varies between sexes and is approximately 45% to 52% for men and 37% to 48% for women.
- Red cell count signifies the number of red blood cells in a volume of blood. The normal range in men is approximately 4.7 to 6.1 million cells/ul (microliter). The normal range in women range from 4.2 to 5.4 million cells/ul, according to NIH (National Institutes of Health) data.
- Hemoglobin is a protein in the red blood cells that carries oxygen and gives blood its red color. The normal range for hemoglobin may differ between the sexes and is approximately 13 to 18 grams per deciliter for men and 12 to 16 grams per deciliter for women.
What causes polycythemia?
Causes of polycythemia are primary or secondary. In primary polycythemia, abnormalities in red blood cell production cause an increase in red cell count. In secondary polycythemia, factors external to red blood cell production (for example, hypoxia, sleep apnea, certain tumors) result in polycythemia.
What are the causes of primary polycythemia?
Primary polycythemias are due to acquired or inherited genetic mutations causing abnormally high levels of red blood cell precursors. Primary familial and congenital polycythemia (PFCP) and polycythemia vera (PV) are in this category.
Polycythemia vera
Polycythemia vera is a rare condition. One study indicated that there were 65,243 patients with PV in the United States in 2003. Polycythemia vera is typically associated with an elevated white blood cell count (leukocytosis) and platelet count (thrombocytosis). An enlarged spleen (splenomegaly) and low erythropoietin levels are other clinical features of polycythemia vera.
Until recently, the exact mechanism of polycythemia vera was not well understood. In 2005, genetic mutations of the JAK2 gene were found to be responsible for most cases of polycythemia vera. These mutations are thought to possibly increase the sensitivity of the red blood cell precursors to erythropoietin, thereby, increasing red blood cell production.
Primary familial and congenital polycythemia (PFCP)
Primary familial and congenital polycythemia (PFCP) is also thought to be caused by genetic mutations resulting in increased responsiveness to normal levels of erythropoietin. Most cases are caused by different mutations to the EPOR gene.


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Warship forum
A forum for the Allied Warships section.
Re: USS PC-1128
Posted by: David Jackson, Jr ()
Date: November 20, 2009 02:50AM
My father (David Jackson) was the executive officer of the ship when it went through Typhoon Louise. I have a significant amount of paperwork, pictures, etc that my Dad left me. He had to go back to the ship with the salvage crew to get whatever they could from the ship as it was stuck on the reef. He had been with the ship for several months including action in the Phillipines. My son in law has a couple hours of video that he recorded several yrs ago when Dad opened up about the war. He talks about his time in the Navy including all his experiences on the ship. Would love to share copies of information including any picture others may have.
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subset: commoncrawl


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S8 Ep8: Season 8, Episode 8
Video duration: 55:00Video has closed captioning.
Hot Town Poster: What role did this striking poster play in the explosive events of 1960s America? Face Jug: Did the artist mean to scare someone with the grimace on this face jug? Lost City of Gold: What does the inscription on a rock tell us about when Spain first arrived in America?


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Hal Leonard Bass Fretboard Basics Book
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Hal Leonard
General Bass Guitar Instruction Books
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Master the bass fretboard with this extremely useful reference book.
Bass Fretboard Basics gives you all you need to know about the bass fretboard, including scales, intervals, triads, modal patterns, and fundamentals; keys, fingerings, position playing; arpeggios, turnarounds, walking bass lines; horizontal and vertical playing; and more! For all styles of playing!


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"Babygirl?" I looked up at Harry through my eyelashes,...
Worth Dying For (Call Of Duty Modern Warfare fan fiction)
- by BVB_Army08
- Rating:
- Published: 18 Feb 2014
- Updated: 26 Sep 2014
- Status: In Progress
I have been play Call Of Duty for a long time now and I figured I should write a fan fiction about it. This is the story of Chris "Specter" Hansen, a 23 year old Lieutenant with the group known as Task Force 141. He normally carries an AK-47, an LSASS, and a Desert Eagle.
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Cross-checking Guidelines
Back to Rules of Cribbage
Cross-checking Guidelines
General considerations:
Detailed information is available from the ACC regional tournament commissioner.
Avoid "serpentine" seating arrangements that make the room one big table.
A private location for checking is always an asset.
Too much help is preferable to too little help.
Corrections made while checking should be initialed by the checker.
Determine the number of qualifiers per the section entitled "Play-off Brackets and Byes."
Collect all players' scorecards. Count them to be sure.
Separate cards by game-point totals, disregarding seating assignments. Place in four piles: definite qualifiers, probable qualifiers, probable nonqualifiers, and definite nonqualifiers (the "dead zone"). Check player's game points
games won to be certain that the two numbers are not transposed (e.g., 14 game points with 29 games won).
Check game-point totals for all but the "dead zone" by going down the
plus spread
column and mentally adding
game points
. Compare with the player's recorded total, and correct it if necessary.
Check point-spread totals in the piles of definite qualifiers and probable qualifiers. Make any needed corrections.
Tiebreakers are, in order:
game points
games won
net point spread
plus points
Segregate the number of needed qualifying cards plus one extra (the presumed "high nonqualifier"). Take note of the high nonqualifier's score.
Separate all of the scorecards by table number, but keep the qualifying and nonqualifying in separate piles. Put each pile in order by seating assignment.
Cross-check in pairs, by tables, with one checker reading to the other. Usually, the person with the qualifying cards reads to the other checker what should be recorded on the nonqualifying cards (e.g., "Seat 5, game 8, lost by 15").
Correct any discrepancies as follows: Do
consult the players involved to adjudicate scorecard errors!
Disadvantage is
to the apparent qualifier. For example, qualifier A claims a 21-point win; opponent claims a 16-point loss; qualifier A's card changed to 16-point win.
Disadvantage can be to two apparent qualifiers. For example, qualifier B claims a 17-point win; qualifier C claims a 16-point loss; qualifier B's card changed to 16-point win and qualifier C's card changed to a 17-point loss.
If the point spread is marked on only one card, this number is accepted for both cards and recorded on the blank card.
If both cards record a win, both cards are changed to losses, with the lower point spread accepted, if relevant.
If only one card records a win but both cards put the spread points in the same column (whether win or loss), the win stands and the spread points on the incorrect card are changed to the appropriate column.
Make sure that game-point and spread-point totals are adjusted, if necessary.
"No harm, no foul": if an apparent qualifier's discrepancy is already to his or her disadvantage, no change is necessary. For example, qualifier D claims a 15-point win; opponent claims a 20-point loss; no change is necessary, and both cards stand as recorded.
If scorecard errors result in a change in the
of qualifying, the tournament director informs the affected player, with the relevant scorecards as evidence.
Check dead-zone cards after each table is cross-checked to be sure that no qualifying cards have been overlooked.
Assemble qualifiers' scorecards in order.
Before posting or announcing play-off pairings, recount and recheck dead-zone cards again.
Post the names of the qualifiers.
Back to Rules of Cribbage
Printable Rules 2016
Membership Form (pdf)
Youth Membership Form (pdf)
For Judge's Test,
send request to:
Al Miller
12 Michael Avenue
Nashua, NH 03062-1418


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On the other side of the ledge, Tom Howard battled with the scar-faced man.
Close by his side, Tom Howard grappled with the scar-faced islander.
If scar-faced Charley, as you call him, can act so well, why doesn't he go on the stage and earn an honest living?
But the eye of Andy, then and thereafter, whenever he was near the five, kept steadily upon the scar-faced man.
Stand up, scar-faced Johnny, and answer the questions I shall ask you.
scar-faced Charley is sitting on a bench on the opposite side of the stockade, with his face buried in his hands.
No sooner had Pete touched Tom than Strong had his paralo-ray gun leveled at the scar-faced man.
It was after making this decision that he and Tom spotted the scar-faced man sitting alone in one corner.
Strong noticed that the scar-faced man paid for them and smiled to himself.
"Pete," answered Strong, suddenly realizing he didn't know the scar-faced man's last name.


text: 9/28/09 9/27/09 POPSUGAR Living Michelle Obama Michelle Obama Walking Bo on the South Lawn September 27, 2009 by Pets 1 Shares Chat with us on Facebook Messenger. Learn what's trending across POPSUGAR. View on One Page Photo 9 of 10 Start Slideshow ADVERTISEMENT () Share This Link Copy ← Use Arrows Keys → 9 Previous Next Bo ObamaMichelle Obama


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TRURO - The impact of the Truro Bearcats' Fred Page Cup winning season was still being felt Thursday in Colchester County.
The Hubtown's junior A hockey team was recognized for its outstanding 2012-13 campaign as it was named the Outstanding Club Team 16 to 20 years during the 30th annual Truro Sport Heritage Society Awards Dinner at Best Western Glengarry.
"It feels great, especially for the guys who played here last year and couldn't make it tonight," Bearcats captain Phillip Fife said. "Obviously it means a lot."
About 350 people attended the event, which featured a meal and dessert before CBC news and sports reporter Bruce Rainnie took to the mike to tell stories about his recent adventures in Sochi, where he was covering the Olympic Winter Games.
The Bearcats were given the nod over the CC Riders under-14 girls Tier 2A soccer squad.
The Bearcats made their first ever appearance at the RBC Cup national championship in May after clinching their first Fred Page Cup Eastern Canadian title on home ice in a thrilling 3-2 double-overtime final over the rival Summerside Western Capitals. Fife notched the winner in that game.
The Bearcats showed they were a force to be reckoned with right out of the gate, rolling through their first 18 regular-season games without a regulation loss. They went on to finish the Maritime Junior Hockey League schedule second overall with 38 wins in 52 games and battled through the Kent Cup playoffs to the final, eventually losing to Summerside just a week before the Fred Page Cup tournament opened at newly minted RECC.
Bearcats coach and general manager Shawn Evans said it was a special season.
"That's something you never know if it's going to happen again," he said. "We had been to the Fred Page before and had no success. That was a special week in a new facility with a great group of players. It's going to be tough to duplicate it."
The evening was also special for both Karlee Burgess and Peter Millman, who were repeat winners of the female athlete 15 and under and male athlete 16 to 20 awards.
Burgess, edged out Erin McCavour and Julia Schmitt for the award.
"Erin McCavour and Julia Schmitt are amazing athletes as well and I'm just really honoured right now," said Burgess, a 15-year-old Hilden resident. "I knew I was going up against some really good athletes and I was happy just to get nominated."
Burgess, who throws second stones for the Mary Fay junior curling rink based out of Chester Curling Club, helped her team win a provincial under-21 title in December. The foursome also claimed the provincial and Atlantic under-18 crowns, storming through Atlantics with a 6-0 record.
As a member of the CC Riders under-16 soccer team, Burgess led the Highland Soccer League in scoring with 16 goals in nine games and was provincial champion in the 400m in track and field. She also won the same event at the Atlantic Legion meet.
"Last year I really wanted to make the legion team and I feel I put a lot of time into track and getting ready for going to legions," Burgess said. "And in curling we were just building and we got a lot of opportunities to get help with our physical and mental fitness."
For Millman, it was his third consecutive nomination for the award. The 20-year-old Truro native and Olympic development program member, finished fifth and seventh respectively in the shot put and hammer events at the Pan American Track and Field Championships in Medellin, Colombia, in July.
A member of the Lethbridge Pronghorns, under the tutelage of Olympic throwing coach Larry Steinke, Millman was named the Can-West conference rookie of the year and Lethbridge's track and field male athlete of the year.
Mike Schmitt took home the coach of the year award after guiding the Truro Pye Chevrolet Bearcats peewee AAA hockey team to a provincial championship. The team posted a 41-19-8 record and also recorded wins in two tournaments and claimed silver in another.
But Schmitt was quick to deflect the credit to his players.
"It's just a reflection of what the team did last year," he said. "Every time I brought something new to the team they accepted it and they just got better and better as the season went on. They were the most excellent group of kids I've ever coached."
Following are winners from Thursday's 30th annual Truro Sport Heritage Society Awards Dinner at the Best Western Glengarry:
Male 15 and under - Gregory McCarthy
Female 15 and under - Karlee Burgess
Club Team 15 and under - CC Riders Tier 2A boys soccer
Junior High Team - South Colchester Wolves boys soccer
Male 16 to 20 - Peter Millman
Female 16 to 20 - Madison Clarke
Club Team 16 to 20 years - Truro Bearcats junior A hockey team
High School Team - South Colchester Wolves girls slo-pitch
Male 21 to 50 years - Jake MacKenzie
Female 21 to 50 years - Anastasia Callaghan
Team 21 and over - Colleen Pinkney curling
Senior Female Athlete 50 and over - Jane Richards
Coach of the year - Mike Schmitt
Volunteer of the year - Raj Makkar
Merit Awards
Truro Daily News - APEX Invitational Golf Association
Tim Hortons - GoTruro.ca
Johnson Saunders - Cobequid Lawn Bowls Club
Special Olympian - Makayla Hadley
Truro Sport Heritage Chair Award - Jake Borden


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Account Director
- Recruiter
- Major Players
- Location
- City of London
- Salary
- £45000 per annum
- Posted
- 07 Nov 2012
- Closes
- 05 Dec 2012
- Ref
- 62037
- Contact
- Rebecca Toll
- Function
- Account Director
- Discipline
- Press / Media Relations
- Hours
- Full Time
- Contract Type
- Permanent
You will need to have a demonstrable track record in running successful campaigns for brands in these fields. You will also need to have a strong working knowledge of social media, an ability to develop creative, brand-building PR campaigns and add strategic value at all levels.
You'll have:
- strong account management skills
- excellent verbal and written skills
- excellent presentation skills
- good understanding of the UK media across all channels including social media
- ability to deliver creative thinking - brainstorms etc..
- strong people management skills
- proven new business track record
- excellent network of contacts
You will be instrumental in driving forward the PR division within the integrated agency and be well suited to work closely with the leadership team to drive the success of the PR division.


text:
How should a facility handle a lay summary that is returned "undeliverable?"
The requirement to communicate results to the patient can be fulfilled by mailing the lay summary to the patient (at the patient's last known address), even when the lay summary is returned to the facility and marked as "undeliverable." While this will satisfy the MQSA requirement, the facility may still be responsible for further attempts at patient communication under their State requirements or Standards of Care. This is especially true where the results are "suspicious" or "highly suggestive of malignancy.
Back to Communication of Results to Patients


text:
"Goodbye America" says the page-three headline in this morning's Metro newspaper.
After 66 years, the story reports, Marvel Comics, is finally laying to rest Steve Rogers, a.k.a. Captain America. The superhero has beaten the Nazis, the commies, terrorists and mutants. But he was brought down by a sniper's bullet as he left a courtroom.
But it was time for him to go. Captain America was invented to defend the land of the free. But now, after the War on Terror… the Patriot Act… and the Prescription Drug Bill… what freedom is left? We are free to dye our hair purple, dress up as a priest and wed a two-headed calf. But that is not the freedom we once looked for.
And so it goes. Every great empire begins in deceit, develops into farce and ends in disaster. The farce – at a high point in the Clinton and Bush administrations – has been great fun. But in order to see what lies ahead we have to be looking far behind. And if we look far enough behind, what we see is old Rome in grand decline. Mind you, it was not a bad time for a man with money and a villa on the coast of Dalmatia. But it was a very sad one for someone who had to rub against the sweating masses thronging the center, or try to hold back the barbarians crowding the periphery.
The Roman emperors spent too much money – on war, on bread, on circuses. They had to clip the coins, rob the citizens, and squeeze the whole empire for tribute to keep up with it. But it couldn't go on forever. The barbarians grew bolder while the empire's own forces weakened. Finally, the Vandals swept across the frontier and brushed aside the remaining defenders, and Rome itself – the capital city of the greatest empire in history – was sacked.
It is an old story. Does it tell us anything useful about the future?
"If there is one thing that can bankrupt America, its health care," said Comptroller General David Walker.
Walker has been giving speeches lately, warning Americans that they are spending too much money. On '60 Minutes' recently, he explained that the Bush administration's Medicare Prescription Drug Bill was the single most disastrous piece of legislation to come along in many decades.
At the center of America's empire is a jolly pack of clowns, liars, and cowards. As to the prescription drug bill, the Bush administration told the nation that it would cost $400 billion in its first 10 years. Now, says Walker, the bill is sure to be closer to $1 trillion. At the present rate of growth, he explained, Medicare and Social Security alone will take up the entire federal budget by the year 2040.
That obviously wouldn't leave much money for keeping the barbarians outside the gates. But here, too, the dissemblers rush in to back up the fools. It was foolish to waste the nation's troops and treasure in a messy war in Mesopotamia. Rome did it… and regretted it… more than once. Now, American centurions patrol the streets of Baghdad while the Caesars on the Potomac inflate the casus belli – all the while deflating the cost estimates.
What happens? What gives? How does it end? We can tell you. Farce gives way to disaster. Sooner or later, the commitments can't be met. The total value of all the household wealth in America is about $50 trillion – about the same amount as the total net 'financing gap' of the Federal government. Which means, dear folks, we are already broke.
But it is not only the feds whose spending is out of control. The U.S. trade deficit, born out of runaway consumer spending, is also careening down a winding road at top speed. Each year, the deficit effectively transfers more U.S. capital to foreign hands. According to figures we found yesterday, now more than half of new federal debt is going to foreigners.
The U.S. current account first went negative in the mid-80s… about the same time that Alan Greenspan took over at the Fed. But it took another 20 years before the total of U.S. assets in foreign hands was so great that the net income from overseas investments turned against the United States. That milestone was passed last year.
Warren Buffett described the situation in his annual report to shareholders last week:
"The 'investment income' account of our country – positive in every previous year since 1915 – turned negative in 2006. Foreigners now earn more on their U.S. investments than we do on our investments abroad. In effect, we've used up our bank account and turned to our credit card. And, like everyone who gets in hock, the [United States] will now experience 'reverse compounding' as we pay ever-increasing amounts of interest on interest…
"Our citizens will also be forced every year to ship a significant portion of their current production abroad merely to service the cost of our huge debtor position. It won't be pleasant to work part of each day to pay for the over-consumption of your ancestors. I believe that at some point in the future, U.S. workers and voters will find this annual 'tribute' so onerous that there will be a severe political backlash. How that will play out in markets is impossible to predict – but to expect a 'soft landing' seems like wishful thinking."
Empires do not typically land softly. They blow up… loudly.
Bill Bonner
for Markets and Money


text:
John Hem Items6 textbooks were found
Study and Interpretation of the Chemical Characteristics of Natural Water (United States Geological Survey Water-Supply Paper 2254)
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text:
Beach volleyball league draws Olympic stars
There wasn't the same amount of media attention. There wasn't the same crowd. There weren't even bleachers. But it was beach volleyball on American soil, and most of the sport's biggest names were present.
Olympic gold medalists Kerri Walsh and Phil Dalhausser, along with the United States' No. 2 women's team, Jen Kessy and April Ross, all played in the National Volleyball League's (NVL) Miami Beach event last September.
Kessy and Ross won the women's competition, but the NVL scored the real victory by getting all the players in the same place.
This week Kessy and Ross return, along with Dalhausser and 2008 gold medalist Todd Rogers, as the teams open NVL's season at Baltimore Beach. The competition then moves to the infield of Pimlico Race Course, where the Preakness will be held Saturday.
Kessy and Ross and Dalhausser and Rogers have qualified for the London Olympics.
The Association of Volleyball Professionals (AVP) Tour went bankrupt in 2010, leaving the United States, the defending Olympic gold medalists in both men's and women's beach volleyball, without a domestic tour.
In its wake came the NVL, the brainchild of 42-year-old Albert Hannemann, an 18-year beach volleyball veteran. Hannemann wanted a tour for the players, created by the players that filled the holes that ultimately sank the AVP.
That meant starting smaller, keeping costs down, and building up from the grassroots.
"It wasn't like I was coming into a situation that was positive," Hannemann said. "It was tough in the marketplace to convince brands to trust in what I was trying to build and get back involved with beach volleyball when beach volleyball didn't exist anymore."
Being one of the best self-promoters as a player, Hannemann found some sponsors to get the league going. Now the task is getting more. That comes from consistently getting the top players to play.
"The one thing that could potentially hold back the sport from growing and getting back to where it was is the players all being on the same page," said Sinjin Smith, a member of the Volleyball Hall of Fame and the leader of the National Collegiate Sand Volleyball Association (NCSVA)."Albert is doing his best to get the top players on board and when he does, when he can tell sponsors and television he has the top players, then he's able to put together events."
With the star players come more sponsors. The NVL announced sponsorships with Asics and Club Med this week.
In addition, amid the music and the roughly 100,000 fans at Pimlico , the NVL will host its event's semifinals and finals. It's the second consecutive year the NVL will be at Pimlico.
By partnering with a larger event, the NVL gets a built-in crowd and cuts costs by only having to pay for the volleyball-related expenses.
"What we're trying to bring is the beach atmosphere to these college fans that are running around," Hannemann said. "They had over 110,000 people there last year and we loved every minute of it. This year it's even bigger because we're working directly with the Jockey Club and we're in their schedule."
But the NVL isn't alone in its quest to grab the U.S. beach volleyball market. The Jose Cuervo Beach Volleyball Tour started around the same time of the NVL and the AVP, under new ownership, plans to make a return soon.
With a fight for the stars possibly on the horizon, it helps that Hannemann is a former player.
"Right when we heard about (the NVL), we were going to support it, because it was run by a player, because he kind of knew what the players wanted," Kessy said.
Hannemann says more than one domestic tour can survive, simply because everybody is doing something different. He says, the NVL for example, is thinking long term.
The league has partnered with junior volleyball events and Smith's NCVSA College Tour, which provides college students the opportunity to compete in regionals around the country.
"The grassroots is something the AVP never really cared about," Hannemann said.


text:
About Us
Interlink Direct Parcel Delivery Service
Interlink Direct is part of Interlink Express which has 99 franchised depots, strategically located throughout the UK and within easy reach of all UK major cities. You'll receive an excellent parcel delivery service from your local courier.
You don't need to set up an account - you simply pay with your credit card / PayPal account and we'll do the rest.
Interlink Direct is the ideal way to take care of all your parcel delivery needs.


text:
|Claim this listing
Shark City Bail Bonds, Inc. is located in San Jose, Ca and is here to help you get your friend or loved one out of jail ASAP. If you have a warrant, Shark City Bail Bonds, Inc. will also assist you in taking care of that warrant, without you having to be taken into custody. Please feel free to call anytime at (408) 221-9922


text:
STV provided design and post-design services for the design-build of a three-story, 138,000-sf Brigade and Battalion Headquarters at Fort Stewart. In addition to architectural and interior design, STV provided civil, structural, mechanical, electrical, plumbing and fire protection engineering. The project includes administrative areas; operations areas; classrooms; and special use spaces for a Secure Compartmented Information Facility, Brigade Operations Center and Network Operations Center. STV incorporated the Southern Colonial Revival style of architecture into its design for the facility, which houses the 4th Infantry Combat Brigade.
See More Projects Like This


text:
When it comes to obtaining short term cash loans, it's very important to do your research first. While you may be feeling like you're in a desperate financial situation, it's crucial to remember that short term cash loans often come with very high-interest rates – so if you're not careful about the loan you accept, you can often find yourself in a much worse financial situation several months down the line.
In this guide, we're going to offer you a few alternatives that can help you to secure the cash you desperately need right now, without risking your long-term financial security. With this in mind, let's dig into the options we have for you.
1 – Use a co-signer
If you have a bad credit rating, it can often be difficult to secure a quality loan with favorable terms and conditions. Of course, the side effect of this is that you're stuck with cash loans that are designed for people with poor credit rating, and these loans often have extortionate interest rates.
However, one option still available to you is to ask a cosigner to cosign the loan with you, and borrow some of the positive credit rating to help you secure a better loan. Of course, your co-signer will need to be someone who deeply trusts you, so this person will usually be a close friend or family member. Ultimately, this is a great way to secure a better loan without risking the exposure to incredibly high-interest rates that can cripple your long-term financial future.
2 – Ask relatives for cash
Another option available to you is to simply ask your friend or family member for cash loan directly. It can be difficult to ask for a loan in this way, but there's no denying that someone who cares about you is likely to give you a better deal than a traditional bank.


text:
21-665 - Solder Aid Kit
Six piece kit includes heat sink, self-closing tweezers, small Phillips screwdriver, brush/scraper, pointed/slotted probe and curved point/scraper
21-7985 - Replacement Tip Cleaning Sponges - 75mm x 45mm
Specific sizes designed for Tenma Stations, ideal for use with any soldering equipment Heat resistant material is unaffected by soldering iron temperature Clean soldering iron tips are essential for maximum life span and effective soldering Sold individually
27-610 - DC Lighter Plug 3A Fuse
DC LIGHTER PLUG 3A FUSE Cigarette Lighter Receptacle, In-line plug, Current Rating: 3 A, Features: With fuse, DC plugs for use in mobile applications
21-1045 - Rosin Core Solder 60/40 Tin/Lead 6OZ.
Rosin Core Solder(six ounces)
Ideal for general purpose electronic repair and assembly use. Tin/lead formulation provides the lowest possible melting point.
21-4773 - Pro-Wick Desoldering Braid - .098" x 5' Blue
Pro Wick® is based on pure rosin (Type R Flux) and meets all of the most stringent soldering standards for worldwide applications: MIL-F-142560D Type R, NASA specification NHB5300.4, NPC200-4, and SP-5002. The advanced braid design has a strong ca...
Easy to find products and order. Items shipped and arrived without hassle.


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Conditional sentence for Bible Hill man who breached probation
TRURO - A Bible Hill man convicted of multiple counts of breaching his probation terms by drinking has been handed a six-month conditional sentence.
Thomas Michael Johnson, 21, of 42 Wright Ave., was ordered to spend the first three months of his sentence at the Harvest House addiction centre in Moncton.
For the following three months he is to be subject to a curfew from 11 p.m. to 6 a.m.
Johnson was also convicted of stealing from the NSLC and of breaking a sprinkler at the Truro police station.
His sentencing conditions also include not possessing or consuming alcohol or illicit drugs, staying away from establishments where booze is sold and successfully taking counselling for alcohol or drug use. As well, Johnson was ordered to not associate with
anyone with a known criminal record.
Impaired driving results in house arrest, probation
TRURO - A Truro man convicted of impaired driving was hit with a four-month conditional sentence and placed on probation for 12 months.
Perry Vincent Shearer, 52, 343 Robie St., Apt. 2, also had his licence revoked for two years.
Shearer is to spend the first month of his sentence under house arrest and the final
three months under a 10 p.m to 7 a.m. curfew.
Sentencing conditions also include not possessing or consuming alcohol or illicit drugs, not entering drinking establishments and being assessed regarding counselling for alcohol use and mental health.
Failure to take counselling results in community service
TRURO - Failing to take counselling as directed and not performing a court-ordered 20 hours community service has led to a six-month conditional sentence for a Truro man.
Alexander Kris Faulkner, 47, of 54 Alice St., Apt. 1, was ordered to spend the first three months under house arrest. For the following three months he is to adhere to a curfew from 10 p.m. to 7 a.m.
During the six months, Faulkner is not to possess or consume alcohol or illicit drugs, stay away from drinking establishments and take counselling for alcohol and drug use and
mental health.


text: oracle-l-bounce@xxxxxxxxxxxxx gravou em 2005-08-12 15:25:19: > PostgreSQL is not a commercial product. Yes, it is. There are several vendors to it. From the top of my head, at least SRA and dbExperts, but I am sure there are others. Fujitsu is funding it, BTW. > I will not comment on that one; Ingres > used to be quite good in the old days. It is still there, but I understand QUEL has been corrupted. > About IBM DB2, which DB2 flavor do you mean? it was a brilliant move from IBM > marketing to call all their (mutually nonexchangeable and even non-comparable) What do you mean by 'nonexchangeable and even non-comparable'? > database products "DB2". If you refer to the mainframe product, I > sort of agree > -- although even that product lacks some serious stuff. For example? > The other products they > call DB2 are inferior to Oracle. Can you specify why do you think it so? I'd be grateful. > SQL/PSM is *not* part of core SQL Yet it is important. > and I personally think the Oracle > proprietary PL/SQL language is much better and more efficient Why? > The other two issues you mention (DATE datatype and > CONNECT BY) were implemented many, many years before even the very first and > lousy SQL standard (SQL86) was established. And badly so. > Backward compatibility issues make > it tough to "fix" such things Borland dit that in a quite elegant way: a switch specifying proprietary or compliant behaviour settable by each application as it gets ported to ISO SQL. -- Leandro Guimarães Faria Corcete DUTRA Administrador de Bases de Dados +55 (11) 4390 5383 Toyota do Brasil Ltda ldutra@xxxxxxxxxxxxx São Bernardo do Campo, SP BRASIL This message (including any attachments) is confidential and may be privileged and intended solely for the use of the person/entity to whom it is addressed. If you have received it by mistake please notify the sender by returning via e-mail as well as delete this message from your system. Any unauthorized use or dissemination of this message in whole or in part is prohibited. Please note that e-mails are susceptible to change. TOYOTA DO BRASIL LTDA (including its group companies) shall not be liable for the improper or incomplete transmission of the information contained in this communication, neither for personal, nonbusiness related information nor opinion sent through this email or even for any delay in its receipt or damage to your system. TOYOTA DO BRASIL LTDA (or its group companies) does not guarantee that the integrity of this communication has been kept nor that this communication is free of viruses, interceptions or interference. -- http://www.freelists.org/webpage/oracle-l


text:
I'll sail another liner, claims Costa captain
The captain of the Costa Concordia, which ran aground off the Italian island of Giglio a year ago with the loss of 32 lives, claims that he will return to the helm of a cruise ship.
Francesco Schettino is facing charges of manslaughter and abandoning ship. Asked outside an employment tribunal, where he was trying to reclaim his job, if he would command a cruise liner again, he replied: "Yes, certainly."
The judge in the tribunal has agreed to the cruise line's request to fast-track the dismissal procedure and said he would announce his decision by the end of next week.
Captain Schettino said: "I have confidence in all the people involved in this process."


text:
Neil deGrasse Tyson
The astrophysicist Neil deGrasse Tyson has spent a distinguished career bringing the universe down to earth in authoritative, innovative and engaging ways. The director of the Hayden Planetarium in New York and the host of the PBS program NOVA ScienceNow, he is a research associate in the Department of Astrophysics at the American Museum of Natural History and the author of 10 books, including Space Chronicles: Facing the Ultimate Frontier.
This event is sold out.
Date: Thursday, April 4, 2013
Time: 7:00 PM
Location: Hammerschmidt Memorial Chapel
Ticket Information:
General Admission: SOLD OUT
Contact Information:
Name: Lu Aiello
Phone: (630) 617-3390
Email: firstname.lastname@example.com


text:
Rapper, producer, actor, and entrepreneur Sean 'P. Diddy' Combs left college while still a teen and within two decades his incredible knack for business has made him a multimillionaire. As the founder and CEO of Bad Boy Entertainment, Combs has been responsible for the careers of many of rap and hip-hops biggest stars. He also started the Sean John clothing line, a successful restaurant chain, created several successful television shows, and secured a major 50/50 partnership and branding deal with Ciroc Vodka brand. He strives to employ young people at his businesses and supports philanthropic efforts to feed and provide for homeless people. In 2013, Diddy started his own television network Revolt TV. As of 2014, Diddy is worth $580 million.
- Born: November 4th, 1969, in New York City
- Height: 5' 11"
- He was nicknamed "Puffy" when a child because he would huff and puff when upset.
- Attended Mount Saint Michael High School in the Bronx -- graduated in 1987.
- Started his career as an intern for the now defunct Uptown Records, and was a dancer in Father MC's video "Treat Them Like They Want to be Treated" in 1991.
- Attended the prestigious historically Black college Howard University and majored in Business.
- His mother, Janice Combs, was a model.
- Successfully ran the New York City Marathon on November 2nd, 2003, two days before his 34th birthday, despite a bum knee, cramps, and minimal training. Combs' highly-publicized effort was for charity, and some of the celebrities who contributed were Eminem, Jay-Z, Ben Affleck, Jennifer Lopez, Busta Rhymes, and Ashton Kutcher.
- In 2008, he received a star on the Hollywood Walk of Fame.
- "I feel safe in white because deep down inside, I'm an angel."
- "It feels like I could go outside with a bikini thong on right now.'"
- "It's okay to be crazy, but don't be insane."


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Results 1 to 6 of 6
Thread: Some mods. That you might like!!
Threaded View
- Join Date
- Feb 2012
- Posts
- 4
Some mods. That you might like!!
Here are a couple of modifications you can do which I think can give you an edge, as it did for me. I use a peep eliminator and think that it is a good product, but I have always thought that the V is too large for an accurate shot. I did this little mod. which made a huge difference for me.
By shaving off the left side of the "V" I was able to line up the vertical pins on my Trophy Ridge sight with the yellow dot on the peep eliminator (see video). It gives me a better view and more accurate alignment.
The Dovetail on the Trophy Ridge sight is quite long which gives me a decent distance between the front and back sight. You can see it in action on youtube at the link below. The view is clearer and the pins can be aligned with greater precision than before. You can see it in action by clicking on the first link below.
The second modification (shown in the second link) gave me the biggest boost in consistancy I have ever gotten with any mod. in my tinkering around.
Let me know what you think or if you have a similar set-up.
Similar Threads
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Prices, specials, features and availability subject to change.
Contact for details
Spacious efficiencies, 1 and 2 bedroom apartments with several different layouts available in this quiet tree lined community as well as beautifully renovated apartment homes. Woodmere is centrally located to all major Transportation Routes as well as the Patco Train Station to Philadelphia. Rowan University is within walking distance to the property and Camden County College is just a short drive away. On site management and 24 hour emergency. Utilities included are heat and hot water. We are conveniently open 6 days. Schedule an appointment today to view one of our apartments.
Pet Policy: Cats ok, 2 pet max. $20 a month pet rent. $250 non-refundable pet deposit. 2 Pet Maximum.
Cats Allowed. Call for service animal policy.
222 units
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OK for the price. I don't like that they control my heat, and that i can hear my neighbors 24/7. rent is low Read More for a reason. I won't be renewing my lease, but the price fit my situation at the time.
November 18, 2014
Bedbugs Poor Maintance
January 14, 2014
The management office is aware of an issue over a year ago, where bed bugs were identified in an apartment. The management office re-acted immediately to this tenant generated issue and resolved the issue with three treatments over the course of 30 days performed by a highly regarded professional.
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What Our Clients Are Saying
"As the Director of Human Resources for a company with over 5000 employees, I rely on FYI Screening to assure me that all background checks sent to them are reliable and accurate. Background reports are always returned in a timely fashion, and I would recommend their services to any of my colleagues."
~ Jennifer Goldring, Director of Human Resources - Ultimate Services, Inc.


text:
Welcome to Meridian Park Radiation Oncology Center
"Always remember you are
braver than you believe,
stronger than you seem, and
smarter than you think"
- A.A. Milne
6489 SW Borland Rd.
Receiving a diagnosis of cancer can be frightening and confusing. To help you and your family better understand the treatment options available to you, we have created this Web site to explain how radiation therapy is used to safely and effectively treat cancer.
The physicians and staff at Meridian Park Radiation Oncology Center are dedicated to provide the highest quality of care to each of our patients. We listen to each patient and their family's particular concerns and needs. We strive to provide excellent and state-of-the-art treatment.
The information on this site was created by physicians and other members of our radiation oncology team with expertise on the topic presented. However, this material is informational only and should not be used in place of specific advice from a medical professional. If you have questions about a specific treatment, please ask your radiation oncologist.


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Structural RNAs:
A. Ribosomal RNA analysis
SILVA rRNA database project (Max Planck Institute for Marine Microbiology, Bremen, Germany ) - provides comprehensive, quality checked and regularly updated datasets of aligned small (16S/18S, SSU) and large subunit (23S/28S, LSU) ribosomal RNA (rRNA) sequences for all three domains of life (Bacteria, Archaea and Eukarya).
RNAmmer 1.2 - predicts 5s/8s, 16s/18s, and 23s/28s ribosomal RNA in full genome sequences (Reference: Lagesen, K et al. 2007. Nucl. Acids Res. 35: 3100-3108)
The Ribosomal Database Project (RDP(Michigan State University Centre for Microbial Ecology, U.S.A.) - provides ribosome related data and services, including online data analysis and aligned and annotated Bacterial and Archaeal small-subunit 16S rRNA sequences.A tutorial is provided here.
Ridom - Ribosomal RNA analysis for clinically relevant bacteria - (University of Würzburg, Germany)
Rifle - (Universitat Bielefeld, Germany) The RIFLE system compares restriction patterns of 16S rDNA amplicons against a database of theoretical restriction patterns generated from a 16S rDNA database
rRNA prediction (hmm_rRNA) - predicts rRNA by using HMMER 3.0 to identify DNA reads containing rRNA sequences. (Reference: S. Wu et al. 2011. BMC Genomics 12:444).
B. Transfer RNAs (tRNA) - for additional information see the genomic tRNA database GtRNAdb or Transfer RNA database tRNAdb
tRNAs: tRNAscan-SE- (Univerisity of California, Santa Cruz, U.S.A,) is incredibly sensitive & also provides secondary structure diagrams of the tRNA molecules (Reference: Lowe, TM, & Eddy, SR. Nucleic Acids Res. 1997. 25: 955-964). tRNAscan-SE 2.0 can also be accessed here. Alternatively use ARAGORN (Reference: Laslett, D. & Canback. 2004. Nucleic Acids Research 32:11-16) or FindtRNA - (D. Paul & Md. Aftabuddin, West Bengal University of Technology, India) - identifies tRNA genes without introns or with introns at canonical or non-canonical positions.
ARWEN - is a program to detect tRNAs in metazoan mitochondrial DNA sequences (Reference: D. Laslett & B. Canbäck B. 2008. Bioinformatics 24:172-175)
Rfam - The Rfam database is a collection of RNA families, each represented by multiple sequence alignments, consensus secondary structures and covariance models (Reference: Gardner, P.P. et al. 2008. Nucl. Acids Res. 37, Database issue D136-D140)
TFAM - unlike other tRNA gene-finders, TFAM uses information from the total sequences of tRNAs and not just their anticodons to predict their function. Therefore TFAM has an advantage in predicting initiator tRNAs, the amino acid charging identity of nonstandard tRNAs such as suppressors, and the former identity of pseudo-tRNAs. New TFAM models are available including a proteobacterial model for the bacterial lysylated isoleucine tRNAs, making it now possible for TFAM to correctly classify all tRNA genes for some bacterial taxa.(Reference: H.Tåquist et al. 2007. Nucleic Acids Res. 35 (suppl 2): W350-W353).
tmRNAs: ARAGORN, tRNA (and tmRNA) detection - detects transfer-messenger RNAs which function to free ribosome-stalled mRNAs. (Reference: Laslett, D., et al. 2002. Nucleic Acids Res. 30: 3449-3453, 2002) .
C. Micro RNAs (miRNAs) are small, non-coding RNA (~20-22 nucleotides) that negatively regulate gene expression at post-transcriptional level.
mirTools - users can: (i) filter low-quality reads and 3/5' adapters from raw sequenced data; (ii) align large-scale short reads to the reference genome and explore their length distribution; (iii) classify small RNA candidates into known categories, such as known miRNAs, non-coding RNA, genomic repeats and coding sequences; (iv) provide detailed annotation information for known miRNAs, such as miRNA/miRNA*, absolute/relative reads count and the most abundant tag; (v) predict novel miRNAs that have not been characterized before; and (vi) identify differentially expressed miRNAs between samples based on two different counting strategies.(Reference: Zhu, E.L. et al. 2010. Nucl. Acids Res. 38 (suppl 2): W392-W397).
MiRPara - is a SVM-based software tool for prediction of most probable microRNA coding regions in genome scale sequences (Reference: Wu Y.et al. 2011. BMC Bioinformatics. 12(1):107).
miR-BAG predict miRNAs from the genomic sequences as well as from Next Generation Sequencing data. It applies a bootstrap aggregating approach to create an ensemble of three different approaches (naïve Bayes, Best First Decision tree and SVM) to achieve a high accuracy. At present miR-BAG includes 6 different species, 4 for animals (Homo sapiens, Canis familiaris, Mus musculus, Rattus norvegicus) alongwith one nematode (Caenorhabditis elegans) and one insect species (Drosophila melanogaster). miR-BAG was found to perform consistently with accuracy level higher than 90% for several species.(Reference: Jha, A. et al. 2012. PLoS ONE 7(9): e45782.)
Small nucleolar RNAs (snoRNAs) - can be detected with Snoscan for methylation-guide for snoRNAs and snoGPS for pseudouridylation-guide snoRNAs (Reference: P. Schattner et al. 2005. Nucl. Acids Res. 33: W686-W689). Test sequences.
sRNAtoolbox: an integrated collection of small RNA research tools. Includes: sRNAbench: Expression profiling of small RNAs and prediction of novel microRNAs from deep sequencing data; sRNAde: Differential expression analysis; sRNAblast: Blast analysis of deep sequencing reads against a local nt/nr (NCBI link) database.(Reference: A. Rueda et al. 2015. Nucl. Acids Res. 43 (W1): W467-W473).
RNA folding:
LocARNA - Multiple Alignment of RNAs - is a tool for multiple alignment of RNA molecules. LocARNA requires only RNA sequences as input and will simultaneously fold and align the input sequences. LocARNA outputs a multiple alignment together with a consensus structure. For the folding it makes use of a very realistic energy model for RNAs as it is by RNAfold of the Vienna RNA package (or Zuker's mfold). For the alignment it features RIBOSUM-like similarity scoring and realistic gap cost. (Reference: C. Smith et al. 2010. Nucl. Acids Res. 38: W373-377).
CARNA is a tool for multiple alignment of RNA molecules. CARNA requires only the RNA sequences as input and will compute base pair probability matrices and align the sequences based on their full ensembles of structures. Alternatively, you can also provide base pair probability matrices (dot plots in .ps format) or fixed structures (as annotation in the FASTA alignment) for your sequences. If you provide fixed structures, only those structures and not the entire ensemble of possible structures is aligned. In contrast to LocARNA, CARNA does not pick the most likely consensus structure, but computes the alignment that fits best to all likely structures simultaneously. Hence, CARNA is particularly useful when aligning RNAs like riboswitches, which have more than one stable structure. (Reference: A. Dragos et al. 2012. Nucleic Acids Reseach 40: W49-W53).
FOLDALIGN - folds and aligns RNA structures (make a foldalignment) based on a lightweight energy model and sequence similarity. The current version makes pairwise fold alignments. (Reference: J. H. Havgaard et al. J. PLOS computational biology. 3:e193, 2007).
For RNA folding use MFold - N.B. The data can be presented in a number of graphic formats. This is my "go to" site if I'm interested in a secondardy structure for a fragment of RNA or DNA (Reference: M. Zuker. 2003. Nucleic Acids Res. 31: 3406-3415).
Vienna RNA secondary structure prediction (University of Vienna, Austria). I have found this site useful for drawing tRNAs in cloverleaf format.
CONTRAfold is a novel secondary structure prediction method based on conditional log-linear models, a flexible class of probabilistic models which generalize upon stochastic context-free grammars by using discriminative training and feature-rich scoring. By incorporating most of the features found in typical thermodynamic models, CONTRAfold achieves the highest single sequence prediction accuracies to date, outperforming currently available probabilistic and physics-based techniques. It provides MARNA-like output couples with hairpin structures (Reference: Do, C.B. et al. 2006. Bioinformatics 22: e90-e98).
RNAiFold 2.0: a web server and software to design custom and Rfam-based RNA molecules - providing a user-friendly pipeline to design synthetic constructs having the functionality of given Rfam families. In addition, the new software supports amino acid constraints, even for proteins translated in different reading frames from overlapping coding sequences; moreover, structure compatibility/incompatibility constraints have been expanded. With these features, RNAiFold 2.0 allows the user to design single RNA molecules as well as hybridization complexes of two RNA molecules. (Reference: J.A. Garcia-Martin et al. 2015. Nucl. Acids Res. 43 (W1): W513-W521).
Web-Beagle: a web server for the pairwise global or local alignment of RNA secondary structures. (Reference: E. Mattei et al. 2015. Nucl. Acids Res. 43 (W1): W493-W497).
Rclick - this web server that is capable of superimposing RNA 3D structures by using clique matching and 3D least-squares fitting. Rclick has been benchmarked and compared with other popular servers and methods for RNA structural alignments. In most cases, Rclick alignments were better in terms of structure overlap. It also recognizes conformational changes between structures. (References: Nguyen MN, & Verma C. 2015. Bioinformatics 31:966-968).
Kinefold RNA/DNA folding predictions including pseudoknots and entangled helices. Provides (i) a series of low free energy structures, (ii) an online animated folding path and (iii) a programmable trajectory plot focusing on a few helices of interest to each user. (Reference: A. Xayaphoummine et al. 2005. Nucl. Acids Res. 33: W605-W6). Structure of GGGAGAUUCCGUUUUCAGUCGGGAAAAACUGAA is shown below:
pknotsRG (Universität Bielefeld, Germany) - is a series of 3 tools for folding RNA secondary structures, including the class of simple recursive pseudoknots. Unfortunately to optimally view the results one needs Microsoft.NET framework (massive) and PseudoViewer(School of Computer Science and Engineering, Inha University, Korea).
HPknotter: A Heuristic Approach for Detecting RNA H-type Pseudoknots - offers a variety of tools including pknotsRG, PNOTS and NUPACK (Reference: C
.-H. Huang et al. 2005.Bioinformatics 21: 3501-3508).
HotKnots - Predict RNA secondary structures with pseudoknots prediction (Reference: Ren, J. et al. 2005. RNA 11: 1494-1504).
vsfold5: RNA Pseudoknot Prediction Server (Chiba Institute of Technology, Japan). Offers lots of control on parameters.
RNAstructure - Predict a Secondary Structure Web Server - combines many separate prediction and analysis algorithms: calculating a partition function, predicting a maximum free energy (MFE) structure, finding structures with maximum expected accuracy, and pseudoknot prediction. This server takes a sequence, either RNA or DNA, and creates a highly probable, probability annotated group of secondary structures, starting with the lowest free energy structure and including others with varied probabilities of correctness.
DotKnot - pseudoknot prediction including kissing hairpins - Intramolecular kissing hairpins are a more complex and biologically important type of pseudoknot in which two hairpin loops form base pairs. They are hard to predict using free energy minimization due to high computational requirements. (Reference: Sperschneider J et al. 2011. RNA. 17:27-38).
IPknot - IP-based prediction of RNA pseudoKNOTs. Provides services for predicting RNA secondary structures including a wide class of pseudoknots. IPknot can also predict the consensus secondary structure when a multiple alignment of RNA sequences is given. IPknot runs fast and predicts the maximum expected accuracy (MEA) structure using integer programming (IP) with threshold cut. (Reference: Satto, K. et al. 2011. Bioinformatics 27: i85-i93.)
Promoters, terminators and other regulatory elements:
Virtual Footprint - offers two types of analyses (a) Regulon Analysis - analysis of a whole prokaryotic genome with one regulator pattern and (b) Promoter analysis - Analysis of a promoter region with several regulator patterns (Reference: R.
Münch et al. 2005.Bioinformatics 2005 21: 4187-4189).
WebGeSTer - Genome Scanner for Terminators - my favourite terminator search program is finally web enabled. Please note that if you want to analyze data from a *.gbk file you need to use their conversion program "GenBank2GeSTer" first. A complete description of each terminator including a diagram is produced by this program. This site linked to an extensive database of transcriptional terminators in bacterial genome (WebGeSTer DB) (Reference: Mitra A. et al. 2011.
Nucl. Acids Res.39(Database issue):D129-35).
ARNold - finds rho-independent terminators in nucleic acid sequences using two complementary programs, Erpin and RNAmotif. The program colors the terminator stem and loop (References: Gautheret D, Lambert A. 2001. J Mol Biol. 313:1003–11 & Macke T. et al. 2001. Nucleic Acids Res. 29:4724–4735 ).
FindTerm (Softberry Inc.) - is one of only two tools on the internet for mapping rho-independent terminators. You might consider using the advanced feature options and minimally increase the default energy threshold to -12.0.
TransTermHP (A. Villegas, Public Health Ontario, Canada) - an online version of TranstermHP, Reference: Kingsford, C. et al. 2007. Genome Biol. 8: R22) an updated version of TransTerm (Reference: Ermolaeva, M.D. et al. 2000. J Mol Biol301: 27-33)
RibEx: Riboswitch Explorer - scans <40kb DNA for potential genes (which are linked to BLASTP) and several hundred regulatory elements, including riboswitches. If you click on the "search for attenuators" it finds terminators and antiterminators. (Reference: C. Abreu-Goodger & E. Merino. 2005. Nucl. Acids Res. 33: W690-W692).
RegRNA 2.0 is an integrated web server for identifying functional RNA motifs in an input RNA sequence. These include Splicing sites (donor site; acceptor site); Splicing regulatory motifs(ESE; ESS; ISE; ISS elements); Polyadenylation sites; Transcriptional motifs (rho-independent terminator; TRANSFAC); Translational motifs (ribosome binding sites); UTR motifs (UTRsite patterns); mRNA degradation elements (AU-rich elements); RNA editing sites (C-to-U editing sites); Riboswitches (RiboSW); RNA cis-regulatory elements (Rfam; ERPIN); Similar functional RNA sequences (fRNAdb); RNA-RNA interaction regions (miRNA; ncRNA). (Reference: Chang TH et al. 2013. BMC bioinformatics 14 Suppl 2:S4).
RegRNA - A Regulatory RNA Motifs and Elements Finder - RegRNA is an integrated web server for identifying the homologs of regulatory RNA motifs and elements against an input mRNA sequence. Both sequence homologs and structural homologs of regulatory RNA motifs can be recognized. The regulatory RNA motifs supported in RegRNA are categorized into several classes: (i) motifs in mRNA 5'-untranslated region (5'-UTR) and 3'-UTR; (ii) motifs involved in mRNA splicing; (iii) motifs involved in transcriptional regulation; (iv) riboswitches; (v) splicing donor/acceptor sites; (vi) inverted repeats; and (vii) miRNA target sites.(Reference: Huang HY et al. 2006. Nucleic Acids Res. 34(Web Server issue):W429-34).
siRNA Design Software - compares existing design tools, including those listed above. They also attempt to improve the MPI principles and existing tools by an algorithm that can filter ineffective siRNAs. The algorithm is based on some new observations on the secondary structure. (Reference: S. M. Yiu et al. (2004) Bioinformatics 21: 144-151).
ARTS (Alignment of RNA Tertiary Structures) - aligns two nucleic acid structures (RNAs or DNAs) in pdb format and detecting apriori unknown common substructures. The identified common substructures can be either large global folds or small local tertiary motifs with at least two successive base pairs. (Reference: O. Dror et al. 2005. Bioinformatics 21 (Suppl 2):ii47-ii53)
CopraRNA is a tool for sRNA target prediction. It computes whole genome predictions by combination of distinct whole genome IntaRNA predictions (Reference: P.R. Wright et al. 2014. Nucl. Acids Res. 42 (W1), W119-W123).
OligoWalk - calculates thermodynamic features of sense-antisense hybidization. It predicts the free energy changes of oligonucleotides binding to a target RNA. It can be used to design efficient siRNA targeting a given mRNA sequence. (Reference: Lu, Z.J. & Mathews, D.H. 2008. Nucleic Acids Res.36:640-647).


text: Happy new year !!! eBanner 2.2 has been released. eBanner is a versatile banner app. I've added following features to it. * Sequential display of multiple messages with varoious styles * Emoji Keyboard Unlocker(You canan use beautiful Japanese picture character) * Improved rainbow color mode. Screenshots You can see a demonstration video at http://www.twitvid.com/E3288 Please visit App Store for more information. WebSite : AcroSoft iTunes Link : eBanner eBanner Lite


text:
Statewide, Wilson placed fifth among the top 10 counties with the lowest unemployment for June 2012. Williamson County was first with a jobless rate of 5.9 percent. Robertson County was 10th with 7.5 percent. Sumner County was eighth with 7.3 percent, and Rutherford County was ninth with 7.4 percent.
Scott County in East Tennessee continues to have the highest unemployment rate in Tennessee at 18.5 percent for June.
The rate increased in all counties in June, according to a news release from the department.
Tennessees unemployment rate for June rose to 8.1 percent, up from the May revised rate of 7.9 percent. The national unemployment rate for June 2012 was 8.2 percent, unchanged from May.
The state unemployment rate is seasonally adjusted while the county unemployment rates are not. Seasonal adjustment is a statistical technique that eliminates influences of weather, holidays, the opening and closing of schools and other recurring seasonal events from economic time series.
Knox County had the states lowest major metropolitan rate of 6.7 percent, up from 6.0 percent in May. Davidson County was 7.3 percent, up from 6.7 percent the previous month. Hamilton County was 8.3 percent, up from 7.4 percent, and Shelby County was 9.7 percent, up from the May unemployment rate of 8.8 percent.


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The two brothers involved in the Boston bombings and their family received as much as $100,000 in government benefits from Massachusetts, according to reports.
The largesse included cash and food stamps as well as help with housing in 2002-12.
In the documents that have yet to be released publicly, an anonymous source with direct knowledge of the details told the Boston Herald the welfare payments received over the 10 years were "stunning" in their breadth.
A full-scale investigation by a committee of the U.S. House of Representatives is set be launched shortly to determine how the substantial sums involved were authorized and why they were granted over such an extended period of time.
[related_links /]
David Linksy, a Massachusetts congressman, told the Herald the committee would thoroughly review all the details of the case.
Americans have a "substantial right to know what benefits, if any, this family or individuals accused…
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Ask Health Experts and Get Answers to Your Health Question ASAP
Dear customer,
I am Dr.Charles and I'm happy to help with your question today.I need the following information from you,so that I can provideyou the complete & best answer:
Is she overweight?
Does she have vertigo or dizziness?
Is there any other known medical illness?
I am online and is waiting for your reply.Kind Regards- Dr. Charles
Overweight - yes, 11st 7lbs height 5ft 4ins
Vertigo - no longer as she received successful treatment for BPPV a year ago
No other medical illness other than occasional bouts of IBS
Muscular pains in the leg, possibly due to statins, but not diagnosed.
(Great difficulty in getting anything diagnosed!!)
Dear XXXXX,Thanks for the valuable info you had given.I've taken a close look at your question & the reply and come up with the following answer:
The symptoms your wife is having can be due to cervical spondylitis and/or spondylosis.It is most likely caused by age-related changes in the intervertebral disks.It is generally caused by the compression of spinal nerves. Any compromise of the nerve space in the spinal column can lead to compression of the nerve endings and can cause the pain & other symptoms.
This occurs because of lumbar radiculopathy,spinal disc herniation,wear and tear or degeneration of the discs. Being overweight is a common cause of this.
She need following tests:
-Electromyography(EMG)-Nerve conduction studies,-Certain blood tests,-Electro physiological studies -Nerve conduction velocity (NCV)
Treatment includes soft cervical collar, analgesics,anti-inflammatory, local heat, possibly traction , and isometric exercises.Exact diagnosis can only be made after physical & clinical examination.So I advice for your wife to make an appointment with her ortho doctor for these tests & examination to know the exact cause & then treatment will be done accordingly.
Till than she can take tab. Ibuprofen 400mg from the counter. It is available as OTC(over the counter) without prescription & will help you greatly.
Hope this helped Your satisfaction is my prime goal and I'm happy to answer any follow-up questions you may have.Please feel free to ask if you have any other question.
Thank you for using again just answer website.
Kind Regards- Dr Charles
Doctor Charles,
Very many thanks indeed. We do feel that your diagnosis is exactly right and we wonder why we have been unable to get this diagnosis from our doctor and from the maxillofacial "experts".
We will now try to get the tests you suggest. Fingers crossed!
Kind regards,


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Unlike conventional surgery, which requires one large incision, laparoscopic surgery is done through several small openings in the abdomen. For patients, that means improved cosmetic outcome, less postoperative pain and a quicker recovery, thus a faster return to work and normal activities.
Who is a candidate for laparoscopic nephrectomy?
Laparoscopic radical prostatectomy is an alternative to standard surgery for removing a cancerous prostate. It can be used in patients who meet special criteria and offers benefits in recovery.
Although not a new procedure, this technique of removing the prostate for patients afflicted with prostate cancer is associated with significantly less blood loss, a hospital stay of less than 48 hours and a fast recovery.
Many men and women with bladder cancer require bladder removal to cure their cancer. Unfortunately, the procedure, called a radical cystectomy, requires the creation of a urinary stoma for urine collection which, although effective, is not aesthetically or socially acceptable to many patients. By using the patient's own intestines, we can create a new bladder that closely resembles and functions like the original organ. We have recently reported our experience with this technique and found that in the majority of both male and female patients, excellent urinary control was achieved. In addition, quality of life and self-image were improved significantly.
In conjunction with Radiation Oncology, a comprehensive program is available to men with prostate cancer who are candidates for this treatment. Many patients have been treated with brachytherapy with excellent results. However, we emphasize individual, customized treatment so that only patients who are good candidates for seed implantation are treated.
Traditionally, the treatment for kidney cancer has been to remove the entire kidney. However, it has recently been shown that in the right patients, removing only the portion of the kidney affected by a tumor offers equal results with the advantage of preserving more renal function.
Minimally invasive, outpatient procedures for BPH include indigo laser therapy and microwave thermal therapy.
Urinary incontinence is a frequent problem that may not respond to conservative measures. Mayo Clinic's incontinence unit offers the latest in surgical correction, such as sling procedures and artificial urinary sphincters. By appropriately selecting the right procedure for each patient, this severe condition can be improved in almost all cases. In addition, our staff offers national expertise in anti-incontinence injection therapies.
In men with Peyronie's disease (abnormal curvature of the penis), reconstructive surgery can straighten the penis with excellent functional results. Similarly, penile prosthetic surgery is offered to individuals for whom other forms of treatment for erectile dysfunction have failed.
This new technique involves placing a small probe directly into the kidney tumor and obliterating the tumor using radiofrequency energy. This is an outpatient procedure done under local anesthesia and does not require overnight hospitalization. Patients also avoid a large incision.
Original article: http://www.mayoclinic.org/departments-centers/urology/florida/services/novel-surgical-procedures
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When does America carry it that it is the fattest mortal surrounded by the world?
When enough race die off so that the birth/death rate reach equilibrium. Then they will care.
Hopefully remarkably soon...
America has to shift its lifestyle we all are aware of it however few want to concordat with the problem pave the way on because it seems similar to such a daunting task
There are tons causes of heaviness besides a sedentary lifestyle and over consumption of wrong calories.There is a host of metabolic problems that go along beside that.Education is key,near should be more emphasis on nutrition lessons in school.Certain fast food restaurants should be forced to serve well again options and consistent foods should be banned.The school need to bring rear legs recess so the kids can stir out and play.There should be better after school comfort for children,and places of work should have breaks for exercise and walking during the daytime.If we want to change America it is going to hold every single person collaborating together.Obesity is not an individual problem its a problem of a society too used to convenience beside little exercise.We need to return to temper and balance.
why is this put somebody through the mill under allergies?


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Luke Le
Luke is the Design Director at Snail Game, the lead and manager for all designers at the studio. Producer of acclaimed titles Black Gold, MiHoo, Dark &Light and Amber.
Project - 5 Street-2, Black Gold, Amber
3ds Max, Beast, HumanIK, Kynapse and Scaleform
Revolution for the MMOG by the magic power of middleware


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Type of Document Dissertation Author Williams, Alicia Marie Author's Email Address email@example.com URN etd-11032008-220541 Title The Hydrodynamics of Ferrofluid Aggregates Degree PhD Department Mechanical Engineering Advisory Committee
Advisor Name Title Vlachos, Pavlos P. Committee Chair Battaglia, Francine Committee Member Paul, Mark R. Committee Member Puri, Ishwar K. Committee Member Stremler, Mark A. Committee Member Keywords
- Ferrohydrodynamics
- Ferrofluid
- Kelvin-Helmholtz
- Magnetic Drug Targeting
Date of Defense 2008-08-01 Availability unrestricted AbstractFerrofluids are comprised of subdomain particles of magnetite or iron oxide material that can become magnetized in the presence of a magnetic field. These unique liquids are being incorporated into many new applications due to the ability to control them at a distance using magnetic fields. However, although our understanding of the dynamics of ferrofluids has evolved, many aspects of ferrohydrodynamics remain largely unexplored, especially experimentally.
This study is the first to characterize the stability and internal dynamics of accumulating or dispersing ferrofluid aggregates spanning the stable, low Reynolds number behavior to unstable, higher Reynolds numbers. The dynamics of ferrofluid aggregates are governed by the interaction between the bulk flow shear stresses acting to wash away the aggregate and magnetic body forces acting to retain them at the magnet location. This interaction results in different aggregate dynamics, including the stretching and coagulation of the aggregate to Kelvin-Helmholtz shedding from the aggregate interface as identified by focused shadowgraphs.
Using TRDPIV, the first time-resolved flow field measurements conducted in ferrofluids reveal the presence of a three-stage process by which the ferrofluid interacts with a pulsatile bulk flow. An expanded parametric study of the effect of Reynolds number, magnetic field strength, and flow unsteadiness reveals that the increased field results can result in the lifting and wash away of the aggregate by means of vortex strengthening. In pulsatile flow, different forms of the three-stage interaction occur based on magnetic field, flow rate, and Reynolds number.
Filename Size Approximate Download Time (Hours:Minutes:Seconds)
28.8 Modem 56K Modem ISDN (64 Kb) ISDN (128 Kb) Higher-speed Access Williams_Dissertation_Final.pdf 8.01 Mb 00:37:04 00:19:04 00:16:41 00:08:20 00:00:42
If you have questions or technical problems, please Contact DLA.


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Montana Sen. John Walsh caught up in plagiarism flap
Published 5:50 pm, Thursday, July 24, 2014
Helena, Mont. -- Sen. John Walsh remained steadfast Thursday amid allegations that he plagiarized a research project required for a master's degree.
The revelations about his 2007 U.S. Army War College thesis, known as a strategy research project, "will not change Sen. Walsh's commitment," his campaign said.
Montana Gov. Steve Bullock appointed the former lieutenant governor to the Senate in February when Democratic Sen. Max Baucus resigned to become ambassador to China
Walsh, a former National Guard general and the only senator who served in the Iraq war, is seeking election in November.
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Walsh said that when he wrote the thesis, he had post-traumatic stress disorder from his service in Iraq, was on medication and was dealing with the stress of a fellow veteran's suicide.
The apparent plagiarism was reported Wednesday by the New York Times. The thesis, titled "The Case for Democracy as a Long Term National Strategy," borrows from a 2003 article in Foreign Affairs, a paper published by the Carnegie Endowment for International Peace and a 1998 paper published by a research institute at Harvard University.


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Would you like to save as your currency permanently or for this visit only?
Large clean room with huge bed and daily room service. Excellent view. Many facilities were not in operation- where was a working spa? Pool needs scrubbing, Internet extremely poor, difficult to use, expensive, didn't get the time we paid for, never experinenced anything so slow. Added an extra night but weren,t given a good rate. Had to pay more! Repainting needed.
Nice, clean and very big bedroom with nice pool/seaview. Great swimmingpool and very good breakfast buffet


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This funny Unicorn Parts T-Shirt labels all the different parts of a unicorn including rainbows, happiness, magic, love and...rump roast? Perfect for unicorn lovers with a sense of humor!
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Brisbane - Apr 14, 2003
Sooner or later, it's hoped, we will reach out to space in a serious way. Not to merely stick another flag on the moon or throw more money at a space station but to gain a permanent foothold out there.
Few people seem to realise the full repercussions of a nation obtaining this kind of capability. Its further reaching in its implications than most of us might care to imagine and bears great importance to the future of arms control. Along with the national prestige and technological spinoffs which would doubtlessly result, from say a Mars mission, there would also be a way of possibly neutralising the nuclear arms buildup.
Nuclear bombs are arguably the most devastating military weapon ever deployed by humankind. As a consequence of their development we have ironically enjoyed generations of relative peace on this planet.
Everyone is just too frightened to start another world war. However, the holiday may be coming to an end as nuclear proliferation starts to escalate uncontrollably. In the beginning only the US had access to this technology and used it to finally end the greatest war this world had ever witnessed. Right or wrong, nobody can seriously question the total unconditional surrender of Japan as not being a direct consequence of the Hiroshima and Nagasaki bombings.
Now the nuclear club is growing towards double figures although many of its new members aren't "officially" recognised. Many nations leaders are unhappy about the way some other countries have the bomb and they don't.
Even those in as close proximity to the US as Mexico have expressed grievances over this issue. It is believed that more than a couple of countries are taking matters into their own hands by developing nuclear weapons arsenals secretly.
It certainly wouldn't be the first time and a nuclear strike is not so intimidating a threat when everybody has the ability to counterstrike. As the number of global arsenals increase so grows the possibility they might in fact be used. Then all hell breaks loose and you can kiss your pension goodbye. We had many close calls during the cold war and can look forward more in the future. It might be the result of international tensions. A flock of birds mistakenly judged by radar operators to be a first strike. Perhaps a terrorist act or a meteor.
One time the Russians mistook a rocket carrying a weather satellite on its way to study the aurora borealis as being a thermonuclear warhead targeted for Moscow. Accidents happen. How do you say sorry for mistakenly decimating a capital city. Is any nation on earth pussy enough not to retaliate if it has the means?
Something of course needs to be done but nobody has any workable answers. Clearly everyone can't be trusted to disarm. Not in the real world. The temptation to hide some warheads would be too great and the shifts in international power would impact us in quite devastating ways. Conventional wars wouldn't be stymied by the nuclear card any more. What if all the racial tensions, political turmoil and religious zeal that has brewed and festered in its kettle for past generations proved stoppable only by the nuclear genie? China would probably invade Taiwan for a start.
Nukes have made more conventional weapons pale into insignificance and countries like North Korea, India, Pakistan and Israel realise the political clout afforded to them by ballistic missiles with nuclear warheads attached. It seems to be a vicious circle we can't escape but can only watch tighten around us.
Only one weapon can do to the nuclear arsenals of this world what nuclear arsenals have done to conventional arms. Yes, a bigger stick does exist although it isn't much talked about. One that makes nukes a less attractive poor cousin by comparison.
Inertia weapons have that potential. What's an inertia weapon? On a smaller scale, inertia weapons known as cars kill over a million people every year. To nations wanting the ultimate weapon no matter what the cost, a space inertia weapon is the holy grail.
We are no strangers to this horror. It has visited numerous mass extinctions upon us in the past. Some of them responsible for removing up to 95% of life on Earth in one swift hammer blow. Everybody now knows that the most likely cause for the demise of the dinosaurs was a comet or asteroid striking around 65 million years ago.
They also know that this created an opportunity for our small furry rat like ancestors to step in and take control. In fact its now believed the biosphere of our planet has almost started over from scratch many many times because of such planetary impacts.
There has been much talk of late on how we might detect and even defend ourselves from such a catastrophe in the near future but nobody seems to be asking the next obvious question. Could such a weapon now be wielded by humans? The answer is a definite yes.
While a nuclear explosion might destroy a maximum radius of approximately 37km due to the curvature of the earth, a large asteroid could decimate an entire continent. Asteroids require no replenishment of fissionable elements or other expensive maintenance and there are millions of them within easier reach than the moon.
It's just like playing billiards. Every object in the universe in accordance with Newtonian laws travels in a straight line unless another force is applied to it.
Unlike billiards there is virtually no friction in space so an object will maintain any velocity and heading indefinitely. At least until its redirected or something stops it.
A spacefaring nation would have no trouble calculating the mathematical solutions for precisely changing an asteroid's trajectory. Then its a simple matter of nudging it. Push in the right spot and maintain the pressure until your gun is pointed at an appropriate target. This might be achieved in many ways.
Reaction mass to drive your inertia weapon could be rocket propellant or the asteroids own mass. Just attach explosives or a few mass drivers. Whoever reaches deep space first will therefore be faced with the choice of utilising these 'inertia weapons' and the temptation will be great indeed. A big space rock could wipe out any enemy and the threat alone would equate to political clout beyond human comprehension.
A city can after all be evacuated if a nuclear strike is threatened, but a country?
If a nation chose to conquer the high ground of space then keeping everybody else out of it would be all that's necessary to ensure world dominance. Inertia weapons cannot proliferate unless more than one nation can actually reach them. The race to space could therefore end up being a race for control of the earth and solar system. I doubt any of this has escaped our leaders, both east and west.
Would this be a bad thing? No worse than the first atomic bomb. The fact that it's unavoidable if we want space travel makes the question absurd. Why wouldn't a space faring nation seize a weapon ensuring it world dominance? Suppose this capability fell into the wrong hands though or was allowed to be owned by many spacefaring nations. Should that happen we might still see nuclear weapons become redundant and inertia weapons replace them as the newest threat to humanity.
It would mean a new "Cold War" on a scale to dwarf the previous US and Russian one. A nuclear war despite all the bad press is in fact survivable. Not all human life would be eradicated and if all the nukes in the world were launched then we in the west might be set back a century. It would be nasty but not the end. It might seem like it but we would eventually recover.
The same can't be said for a space war where mountains are directed at the earth.
When the first space probe experimentally landed on the asteroid Eros recently, that celestial bodies motion was imperceptibly changed by the gentle bump of a manmade spacecraft for the very first time. A herald of greater things to come maybe. Nobody can accurately predict the future and I don't want to add my name to the long list of failed seers in history.
The technology however is more than a prediction and has existed for a very long time. A new space race looks set between the US and enthusiastic newcomer China which I would call a safe bet. Now what do we do if China one day announces Ceres to be on course for the US and they want Taiwan in exchange for "assistance"?
We might truly learn what it means to see the sky falling.
In the movies "Armageddon" and "Deep Impact" we saw nukes save the earth in from both a rogue asteroid and a comet. Perhaps it will ironically prove to be the other way around. The threat of genocide from space might be persuasive enough to make nations disarm.
Ultimately averting a future nuclear war. Expensive nuclear warheads would become second rate weapons.
Expensive and redundant ones in the face of that firepower.
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Nuclear Space And Fears Of Nuclear Proliferation
Brisbane - Mar 25, 2003
According to New York's Democratic Senator Charles Schumer, "It doesn't matter how good our airport security is if all it takes to bring a nuclear device right into midtown is putting it on a ship or bringing it in on a truck."
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David McLaughlin has worked in both federal and provincial PC campaigns and been Chief of Staff to former prime minister Brian Mulroney, New Brunswick premier Bernard Lord, and finance minister Jim Flaherty.
Progressive Conservative leader Tim Hudak has set the focus of Ontario's election campaign.
His platform – the Million Jobs Plan – is dominating the election narrative. Few other promises by any of the leaders have caught public attention; neither Liberal leader Kathleen Wynne's provincial pension proposal nor NDP leader Andrea Horwath's GST cut on hydro rates.
Mid-stream, this campaign is all about jobs. Specifically, one million private sector jobs Mr. Hudak hopes to create and 100,000 public sector jobs he plans to cut.
That plan is now under attack. That was to be expected and, indeed, welcomed. Cries that 'It can't be done' or 'don't cut government jobs' would simply validate their message and man. It was political catnip to the opposition and they predictably pounced.
Having successfully made its platform the defining issue of the campaign to date, it is the unexpected reasons that are threatening the PC campaign's strategy. The calculations adding up to the million new jobs are being attacked as wrong. Not wrong in principle, but evidently wrong in math.
This is a dangerous moment for Mr. Hudak. His core campaign thrust and credibility risks being blunted. Never mind that neither the Liberals nor the NDP have provided full detailed costing of their platforms. The PC platform's unapologetic brashness and clarity made it a target.
In politics, bold can easily become rash. The PC platform illustrates the perils when the former slides into the latter.
It need not be this way. Successful election platforms have their own strategic political calculus. Three factors matter most.
First, and foremost, platforms are campaign documents. They are a tool to win the election, not the full roadmap to govern after the election. They are meant to tell voters what issues matter during the election, not an exact plan for every government decision expected to be taken during the next four years. Their most important shelf life is about thirty days. That is why campaigns make conscious choices about what goes in a platform and what does not.
Second, platforms are communications documents, for voters and candidates alike. The words and messaging are meant to both resonate with targeted voters and keep candidates focused on the issues, promises, and language the campaign wants. They seek to tell voters what matters most for them in this campaign by setting out priorities, such as jobs or health care or education. Since 99 per cent of voters do not read a platform in its entirety, simple, activist language with lots of easy-to-follow bullet points is the norm.
Third, platforms are tactical documents, meant to shape the pace and pattern of the election, undermine opponents, while eliminating any weaknesses in your image or positions. The PC platform shows this in action. Releasing it first and early in week one, as Mr. Hudak did, shifted the focus to him and his party capturing the media oxygen that breathes life into every campaign. It undermined any momentum the Liberals had with their own budget just days before. And it addressed, at first at least, lingering doubts about Mr. Hudak's readiness for governing by offering up a coherent plan.
The PC platform actually passes muster from this overall calculus. But, none of this matters if a platform fails to meet the iron rule governing all platforms: do no harm. An unexpected mistake, contradiction, or just an unambiguous promise can grow into something more meaningful and menacing to a campaign.
That is what the Ontario PCs now face. The promise to cut 100,000 government jobs was meant to be controversial. The million new jobs promise was not.
It is not often a party and a leader have so personified an election platform. Jean Chrétien did with his 1993 federal election Red Book and, of course in Ontario, Mike Harris did with his Common Sense Revolution in 1995. Both were successful.
Mr. Hudak and his platform are now one.
This makes it impossible for the PC leader to disown any or all of his platform, even if he was so inclined. Voters may prove to have a more benign view of the significance of this current controversy. Lots else can happen between now and June 12th.
However this turns out, one thing is clear. Mr. Hudak has the campaign he sought. But his opponents now think they do too.Report Typo/Error
Follow us on Twitter: @GlobeDebate


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Selena Gomez and The Weeknd can't keep their distances from each other!
The hot and heavy couple was spotted at 1Oak nightclub Sunday night for Rihanna's after-party after the 59th Annual Grammy Awards. The duo arrived separately, but when it was time to call it a night they left together in the same car. RiRi's star-studded party also included appearances by French Montana, James Harden and Scott Disick.
A source also told us that The Weeknd "hung out in a booth on the patio the whole time." Earlier in the evening The Weeknd attended Republic Records' after-party at Catch that was sponsored by Fiji Water and Freixenet Cava.
While these two were partying the night away after The Weeknd's performance, Gomez's ex-boyfriend, Justin Bieber, was using Instagram's live feature to shade his ex's current boyfriend. The 22-year-old singer sarcastically quipped that his "favorite song of the moment" was "Starboy" by The Weeknd. He and his friends then broke out into hysterical laughter.
"Oh s--t, that was funny," Bieber's friend says off camera.
"We gotta end it now, y'all," Bieber added. "Y'all, that was too funny."
Of course, fans know that this wasn't the first time the Biebs has called out The Weeknd. In January TMZ caught up with Bieber and asked if he enjoyed The Weeknd's tunes.
"Hell no, I can't listen to a Weeknd song," Bieber replied. "That s--t's whack."
Neither Gomez nor The Weeknd has publicly acknowledged Bieber's comments, but they're obviously paying no mind.


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Utah Red Cross workers were providing temporary shelter, food and clothing to two elderly women after an early Thursday morning fire damaged their Millcreek home.
Unified Fire Capt. Clint Mecham said the 8:13 a.m. blaze at 4312 S. 615 East is believed to have been caused by a malfunctioning freezer located in the home's kitchen.
The women, one in her 90s and the other in her 70s, called 911 when they saw smoke billowing from the kitchen. Firefighters arrived within four minutes and safely evacuated the women and their pet dog from the residence.
No injuries were reported.
Crews extinguished the flames by 8:32 a.m., but in doing so had to remove sections of sheetrock walls and ceiling. Smoke and water also added to damage, which was not immediately given a dollar value but was sufficient to render the home temporarily uninhabitable.
Twitter: @remims