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The shock exit of England's sixth highest wicket-taker, mid-way through an increasingly traumatic Ashes tour, has left the selectors with a huge hole to fill at 3-0 down with two Tests still to play.
Monty Panesar travelled down under as Swann's deputy and joined him in a losing side at Adelaide, but an SOS has also been sent to Durham leg-spinner Scott Borthwick and Kent tweaker Tredwell.
Borthwick, who has been playing Grade cricket in Sydney, will be available for the Boxing Day Test in Melbourne, with limited-overs mainstay Tredwell joining up in time for the series finale in Sydney.
That leaves England with three viable alternatives by the end of the series but Tredwell insists the challenge of matching Swann, who claimed 255 wickets in 60 matches, is a daunting one.
"I've shown what I can do over the last few months, certainly in the one-day game, and I've played a Test before, so I think I've proved I can do it at this level," the 31-year-old told Sky Sports News.
"But it's about showing you can do it over a period of time. It's not going to be easy to emulate Swanny's feats over the last few years, but it's there for someone like myself to put my hand up.
"There's no doubt his accomplishments are vast and to fill those shoes will be quite difficult but that is the challenge of sport.
"A lot of people compare him to (England's most prolific spinner) Derek Underwood and the feats he accomplished...for him to put in the match-winning performances he has over his England career is something to behold and it's going to be a real challenge for the next person."
With Borthwick still relatively raw, Tredwell is in no doubt who will get the first chance to stake their claim but has promised to do what he can to press his own case.
"Monty is obviously in the box seat at the moment and he is going to get the first opportunity," said Tredwell.
"(But) I'm there for the fifth Test in Sydney and that can be the ground in Australia that can turn at times. I'm just going to go out there and do what I can to put my name in the ring and see what comes.
"If you get that opportunity you want to take it with both hands and make contributions to a winning team."
Tredwell, who has successfully stood in for Swann with the white ball in the past - taking 36 one-day wickets at 24.88 - was keen to play down suggestions of a dressing room rift.
He may not be in Australia at present, but he has been around often enough to believe Swann's comments about certain international players being "up their own backsides" was not aimed at his own colleagues.
"Sometimes you get in a scenario in a press conference or interview when you say odd little phrases that get construed the wrong way," Tredwell said.
"The England cricket team over the last however many years, when it has been very successful, has had cohesion in the group.
"I can't see that being an issue."Reuse content


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Compare home loan quotes in Woodburn, Oregon! Browse our directory of Woodburn mortgage brokers or simply fill out the quick form above to compare a Oregon mortgage from lenders in Woodburn, Oregon.
Before working with a mortgage broker, use our various tools to calculate your budgeted monthly home loan payments, track local mortgage rates and learn about the many lending products and services available.

subset: commoncrawl


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Thanks to media exposure and some helpful citizens, El Dorado County sheriff's officials have apprehended a suspect in the $7,000 theft that occurred in El Dorado Hills earlier this month.
On May 20 a previously unknown man broke into the Town Center Bike and Tri shop on Town Center Boulevard. When he left the shop he took a bicycle and bicycle accessories worth approximately $7,000. Photographs were obtained of the suspect and through the media the public was asked to help identify him.
Thanks to the media and those in the public who responded to the Sheriff's Office's request for assistance, Det. Troy Morton was able to identify the suspect and obtain a search warrant for a location in Sacramento and another location in West Sacramento. While serving the search warrant Morton recovered the Town Center Bike and Tri stolen property and other stolen property from a crime committed in another jurisdiction. Morton took the suspect, 40-year-old Brandon Lee Rose, into custody.
Sheriff John D'Agostini and his staff expressed thanks to the media and the public for their assistance in solving these cases and remind residents to stay vigilant. If someone observes any activity, person or circumstance that appears suspicious, report it.


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Godsmack's Sully Erna Talks Historical Single '1000hp'
Listen to Godsmack Radio on iHeartRadio
Godsmack is nearing its 20th anniversary. So frontman Sully Erna says it felt right that the group ended up writing the song "1000hp," which deals with the band's beginnings.
Erna says they probably couldn't have penned the lead single and title track from their new album at any other point in their career. Plus, he notes that it only came together once they were all in the same room after writing some of the other new songs separately. In Erna's mind, that's when they came up with the album's strongest material.
[RELATED: Watch Godsmack Perform At The iHeartRadio Theater!]
Godsmack recently performed at the iHeartRadio Theater in New York City recently. Check out their performance of "1000hp" below!
The guys also spent some time backstage before their exclusive iHeartRadio show ... saying nice things ... in Godsmack fashion. Check it out:
Photo: Getty Images


text: On Wed, 11 Jun 2008 16:04:59 +0100, Richard W.M. Jones wrote: > On Tue, Jun 10, 2008 at 12:24:36PM -0400, buildsys fedoraproject org wrote: > > ocaml-deriving: > > F8-updates > F9-updates (0:0.1.1a-4.fc8 > 0:0.1.1a-3.fc9) > > > > ocaml-gsl: > > F8-updates > F9-updates (0:0.6.0-4.fc8 > 0:0.6.0-3.fc9) > > > > ocaml-json-static: > > F8-updates > F9-updates (0:0.9.6-4.fc8 > 0:0.9.6-3.fc9) > [etc etc] > > Is this wrong? > > I'm afraid to say that a lot of packages I have do this. The reason > is that I develop and build packages on Rawhide, then backport them to > F-8. However when backporting to F-8 I have to bump the release > number up, typically because I have to add an ExcludeArch: ppc64[*] > for F-8, but may be because of other packing twiddling too. That's no reason. %if 0%{?fedora} > 8 # something %endif Effectively, you can create a spec file in "devel" which you can copy unmodified to older branches. If, however, you really need to modify'n'bump an older branch only, increase the "Release" value in the least-significant position at the very right, 4%{?dist} => 4%{?dist}.1 => %{?dist}.2 => and so on but if it's just minor modifications, you better use the %fedora macro as above. > I wasn't aware that there had to be a strict increase in package > numbering between branches. (In fact, I wasn't aware that Fedora even > allowed updating between Fedora releases). What do you think why does Anaconda support distribution upgrades? It has been the official upgrade method for many years (as with old Red Hat Linux), and our users do also Yum/Apt-based dist-upgrades.


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Courtney Stodden's Sham Marriage Might Be Sham Disintegrating
- Courtney Stodden, 17, and her 52-year-old husband Doug Hutchinson have been cast on VH1's "Couples Rehab," which means their sham marriage may be on the rocks. You guys! This would the biggest breakup since Robsten! Bigger even! [Rolls eyes.] [TMZ]
- "Ghostbusters 3″ news: Dan Ackroyd says production will begin next year, but Bill Murray will not be involved in the film. Lame. [Celebrity Cafe]
- Katie Couric is dating a new dude: financier John Molner. What is it with these famous women dating men whose job title is "financier"? Where can an average girl like me find one of those? [People]
- Heidi Montag "wouldn't really recommend" that you have 10 plastic surgeries all at once like she did. So now you know not to do that. [Celebuzz]
- LaToya Jackson will film a reality show for Oprah's network, OWN. She's the one with a psychic hotline, right? [Celebrity Cafe]
- If only Disney movies had modern technology in them, things might have turned out much differently for these famous characters. [Em & Lo]
- Your body is the same size as an Olympic athlete's — here's how to find your match! [Gurl.com]
- Russell Brand allegedly harassed a wardrobe girl to show him her tits on the set of his new film. [Jezebel]
- Vegan diets might not be as healthy as you think. [Yahoo Shine]
- "Saturday Night Live"'s Seth Meyers is developing a comedy called "Hotel California" about running a swanky L.A. hotel. [Hollywood Reporter]
Contact the author of this post at [email protected] Follow me on Twitter and Tumblr.
[Photo: SplashNews]


text:
Electrical Questions? Ask an Electrician Online.
Hi Jason,
Sorry it took so long to update you on the issue, but I haven't had a day off work since October 2nd and just didn't have time to work with the breakers or wires.
I did get the issue resolved. There was a bad breaker which I did replace, and I found the open ground to an old model baseboard heater. The heater doesn't work and was on my list to replace, so I just removed it and disconnected it from the breaker box completely. I doubt that had anything to do with the main issue, but figured it couldn't hurt.
After that, I really couldn't get the problem to repeat no matter what I tried, so I think the problem is resolved. But I did go ahead and put the furnace on its own dedicated breaker anyway.
Thank you so much for all the information. I would have never figured this out on my own and was getting quite frustrated.
I am very happy with the help you gave. Thank you again.


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LOS ANGELES -- In most Hollywood fare, when a woman is complicated, it just means she can throw a punch.
It's a point not lost on January Jones as we sit down for an interview in a Beverly Hills hotel.
"That's so true," she says in a Canadian newspaper exclusive. "Female complexity does mean you have to be masculine in a way."
Jones, if you haven't guessed, is the decidedly unmanly exception.
Consider her role as brittle, miserable, graceful, rigidly feminine housewife Betty Draper in TV's Mad Men. In the past four seasons, the suave 1960s-set series has both celebrated her demure genetic classicalism -- Alfred Hitchcock surely would have cast her as a chilly, inscrutable blonde in one of his thrillers of obsession -- and subverted it.
The results have earned Jones both acclaim as an actress (she's been nominated for an Emmy) and status as a style icon (Donatella Versace hailed her as the most glamorous actress of our time).
"For an actor, especially for a woman, it's a dream come true because there are so few roles that are written so complex and layered and strange and ugly," she says, calling the decision to sign on to Mad Men "the biggest risk I've ever taken in my career. You're signing five years of your career and life away with two lines in a pilot. And I'd never done TV. It could have gone so horribly wrong."
After all, back in 2007, Mad Men was the first series launched by then-upstart cable network AMC. Its star, Jon Hamm, was an unknown. And its creator Matthew Weiner, while a veteran writer of The Sopranos, had never run a show before.
"Matthew wasn't even sure Betty was going to be a part of the show. So for him to take not two lines in the pilot and have him verbally promise me he'd give me something interesting, and to have what I've gotten over the past four years with Betty, is amazing. It keeps challenging me.
"It keeps giving me harder, weirder, more emotionally challenging things."
It has also put Jones -- whose pre-Mad Men credits included The Three Burials of Melquiades Estrada and American Wedding -- in high demand.
Case in point: On Friday, she stars opposite Liam Neeson in the psychological thriller Unknown. She portrays another strong spouse: the wife of a doctor (Neeson) who, after a car crash during a business trip in Berlin, wakes up from a coma to discover he's been replaced by an imposter (Aidan Quinn).
Confounding the mystery and his dilemma is the fact his wife doesn't recognize him. (What was I saying about Hitchcock blonds?) Eventually he's aided by a cab driver (Diane Kruger) and a former East German spy (Bruno Ganz) in unravelling the conspiracy.
"It was something I hadn't done before. I hadn't done an action film before," Jones says. "The character was undefinable in that you don't know whether she's a good guy or a bad guy or what the reality is. And getting to shoot in Berlin with Liam and Diane, it just seemed like a fun time. It was a really smart script and a director I really liked. Everything just added up. Sometimes you take that chance and the movie could just be so-so, but I'm very, very pleased -- it's a great film."
And she will follow Unknown with two more big-screen roles: opposite Nicolas Cage in the thriller The Hungry Rabbit Jumps, and as the manipulative mutant Emma Frost in the prequel X-Men: First Class.
"The whole fun part of this job is the risks you take. Sometimes you may not succeed, but the times you do, it's so much fun and exciting. That's what makes it worth it, I think."
Despite the burgeoning film career, she also expects to return to Mad Men for a fifth season in the near future. As of yet, there's no word when the series will be back.
"I never know until they tell me to be at work, literally. Each season, there's always the drama of whether Matthew Weiner will be back and is he going to sign a deal and he always does.
"So it's just a matter of time. We don't have a set pocket of when we have to start shooting or need to air. I'm not too worried about it."
Nor does she think just because Betty and advertising executive Don Draper (Hamm) have divorced and re-married that her role will be reduced.
"I think she'll come back a lot more this season. I think because Don and Betty aren't together you're not going to see the home life as much. I'm not sure what will happen there. I think somehow their lives intertwine more."
When I suggest Don and Betty should start cheating with each other on their new spouses, Jones smiles. "That's what I said too. That would be awesome. You always want what you can't have. I've already put my two cents in about that storyline.
"Jon and I get along really well, so we'd have fun with that. We wouldn't have to yell at each other all the time."
Then again, because it's such a tantalizing prospect, it probably means it will never happen.
"Matthew doesn't like to write for an audience. He's not going to give you what you expect ... It's fun for him and it's interesting for everyone that way."
Jones thrilled with 'X-Men' prequel
LOS ANGELES -- The new X-Men prequel continues to mutate even though it's scheduled to open in June.
"Poor (director) Matthew Vaughn is going to have to edit it in three days," January Jones says, laughing. "That's been a blast. We've all had so much fun making that movie."
Entitled X-Men: First Class, the film chronicles the origins of Marvel's super-powered mutant population. Set in the 1960s, it stars James McAvoy and Michael Fassbender as a youthful Professor X and Magneto, respectively. Jones joins the franchise as Emma Frost aka The White Queen, a scantily clad blond with telepathic powers.
Vaughn's previous credits, including Kick-Ass and Layer Cake, may inspire confidence, but usually when a film is still shooting this close to its release date, it signals trouble.
Jones, however, predicts fans will be pleased.
"I think it was unrealistic for them to think they were going to make such a huge movie in whatever we had -- two months or something. So of course we went over (schedule). I think I have a couple more days to shoot.
"We're almost done. The fact we've had to push the wrap date but they haven't moved the release date is really interesting to me. I guess they must know what they're doing. I have a lot of faith in Matthew as a director and an editor; I think his movies are great. And I think they've been cutting as we've been going. We should be fine."
As is true of most female comics characters, Frost isn't known for being over-dressed. And neither apparently will Jones be in the movie.
"Everybody wants to know about the costume," she says. "I didn't really know much about her beforehand, but when I did my research, she's a very -- specifically visually -- iconic character. Nobody talks about the fact she's got the most bad-ass powers.
"But yeah, she has very skimpy outfits. So we had a lot of fun with that."
More Artists


text:
Metformin / repaglinide Side Effects
In Summary
Commonly reported side effects of metformin/repaglinide include: lactic acidosis, diarrhea, hypoglycemia, and nausea. Other side effects include: decreased vitamin b12 serum concentrate. See below for a comprehensive list of adverse effects.
For the Consumer
Applies to metformin / repaglinide: oral tablet
In addition to its needed effects, some unwanted effects may be caused by metformin / repaglinide. In the event that any of these side effects do occur, they may require medical attention.
Major Side Effects
You should check with your doctor immediately if any of these side effects occur when taking metformin / repaglinide:More common:
- Anxiety
- blurred vision
- body aches or pain
- chills
- cold sweats
- coma
- confusion
- cool, pale skin
- cough
- depression
- difficulty in breathing
- dizziness
- ear congestion
- fast heartbeat
- fever
- headache
- increased hunger
- loss of voice
- nasal congestion
- nausea
- nervousness
- nightmares
- runny nose
- seizures
- shakiness
- slurred speech
- sneezing
- sore throat
- unusual tiredness or weakness
Minor Side Effects
Some of the side effects that can occur with metformin / repaglinide may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common:
- Diarrhea
- vomiting
For Healthcare Professionals
Applies to metformin / repaglinide: oral tablet
Very common (10% or more): Gastrointestinal system disorder (33%), diarrhea (19%), nausea (15%)
Very common (10% or more): Gastrointestinal system disorder (36%)
Common (1% to 10%): Diarrhea, nausea
Postmarketing reports: Pancreatitis
Very common (10% or more): Gastrointestinal system disorder (48%), diarrhea (30%)
Common (1% to 10%): Nausea[Ref]
Postmarketing reports: Severe hepatic dysfunction including jaundice and hepatitis[Ref]
Nervous system
Frequency not reported: Headache[Ref]
Very common (10% or more): Upper respiratory tract infection (11%)
Very common (10% or more): Upper respiratory tract infection (11%)
Common (1% to 10%): Upper respiratory tract infection (11%)[Ref]
Postmarketing reports: Hemolytic anemia[Ref]
Postmarketing reports: Stevens-Johnson syndrome, alopecia[Ref]
Cardiovascular events were evaluated in trials comparing repaglinide to sulfonylureas. Serious cardiovascular events including ischemia with this drug were higher at 4% (51/1228) than for sulfonylurea drugs (3%; 13/498). No excess mortality was associated with this increase. Selected cardiovascular events including hypertension, abnormal EKG, MI, arrhythmias, and palpitations were observed at 1% or less and no more frequently with this drug than with comparator drugs.
Across 7 repaglinide clinical trials, 6 serious events of myocardial ischemia occurred in combination use with NPH-insulin compared with 1 event in patients using insulin alone. Repaglinide should not be used in combination with NPH insulin.
Common (1% to 10%): myocardial ischemia, angina, chest pain
Frequency not reported: Hypertension, abnormal EKG, MI, arrhythmias, palpitations
The most frequently reported adverse reactions included hypoglycemia and headache.
Very common (10% or more): Symptomatic hypoglycemia (33%)
Very common (10% or more): Symptomatic hypoglycemia (11%)
Common (1% to 10%): Subnormal vitamin B12 levels
Rare (less than 0.1%): Lactic acidosis
1. "Product Information. PrandiMet (metformin-repaglinide)." Novo Nordisk Pharmaceuticals Inc, Princeton, NJ.
Not all side effects for metformin / repaglinide may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about metformin/repaglinide
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- Pricing & Coupons
- En Español
- 0 Reviews – Add your own review/rating
- Drug class: antidiabetic combinations
Consumer resources
Other brands: PrandiMet
Professional resources
Related treatment guides
Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.


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Aleph Number:
Collection is open to research.
However, access to some records is limited to photocopies of the original documents.
Researchers must register and agree to copyright and privacy laws before using this collection.
All or portions of this collection may be housed off-site in Duke University's Library Service Center. There may be a 48-hour delay in obtaining these materials.
Please contact Research Services staff before visiting the David M. Rubenstein Rare Book & Manuscript Library to use this collection.
The copyright interests in this collection have not been transferred to Duke University. For more information, consult the copyright section of the Regulations and Procedures of the David M. Rubenstein Rare Book & Manuscript Library.
[Identification of item], J. Walter Thompson Company. Corporate Documentation, David M. Rubenstein Rare Book & Manuscript Library, Duke University.
The J. Walter Thompson Company. Corporate Documentation collection was received by the David M. Rubenstein Rare Book & Manuscript Library as a transfer in 1987 with additions in subsequent years.
Processed by Richard Collier, September 2007
Encoded by Richard Collier, September 2007
Materials may not have been ordered and described beyond their original condition.
Corporate Documentation primarily consists of minute books to the regular meetings of JWT's stockholders and Directors; administrative and finance records; and reports from JWT's subsidiaries, committees and other institutional bodies. Topics covered include annual assessments of agency performance; planning; by-laws; stock incentive plans and retirement plans; and efforts to standardize operational practices across the many offices of JWT. The collection also includes background information relative to annual meetings, and the anniversaries of various offices.
The collection derives from the RG1 record group,
Records have been arranged into five topical series:
Includes correspondence 1942-1964
[Unbound materials including: Thompson Briggs Company, 1911; J. Walter Thompson Advertising Company, 1931-1936; New Jersey and New York incorporations]
[Nancy Fitzpatrick was Vice President and Assistant Secretary of JWT]
[Luther Orange Lemon (1900-1957) was Treasurer and Director of JWT]
[John J. Cronin was President of the Toronto Office of JWT]
[Primary task of the Committee on Standardization was to establish uniform practices across all JWT offices and operations]
Includes minutes and annual reports
Includes Agency Art Associates; Channel 3 Workshop; Diogenes Marketing Research; Ficho & Corley, Inc.


text:
H.R.2949 - Eurasia Foundation Act110th Congress (2007-2008)
|Rep. Wexler, Robert [D-FL-19] (Introduced 06/28/2007)
|House - Foreign Affairs | Senate - Foreign Relations
|Latest Action:
|11/06/2007 Received in the Senate and Read twice and referred to the Committee on Foreign Relations. (All Actions)
This bill has the status Passed House
Here are the steps for Status of Legislation:
- Introduced
- Passed House
Subject — Policy Area:
- International Affairs
- View subjects
Summary (2)
Text (3)
Actions (10)
Titles (3)
Amendments (0)
Cosponsors (28)
Committees (2)
Related Bills (1)
Summary: H.R.2949 — 110th Congress (2007-2008)All Information (Except Text)
Shown Here:
Passed House amended (11/05/2007)
Eurasia Foundation Act - (Sec. 3) Directs the Secretary of State to make an annual grant to the Eurasia Foundation to: (1) promote civil society, private enterprise, and public administration and policy in the countries of Eurasia; (2) strengthen indigenous institutions that foster national development, social change, economic growth, and cooperative international relationships consistent with U.S. interests in Eurasia; and (3) conduct programs in the region that would be difficult or impossible for an official U.S. entity.
Expresses the sense of Congress that: (1) an appropriately funded Foundation can contribute significantly to the political, economic, and social development of democracy and human rights in the countries of Eurasia; (2) organizations that seek competitive grants typically perform in a more transparent and effective manner; and (3) the Foundation should seek competitive grants to supplement federal appropriations.
(Sec. 4) Sets forth grant eligibility provisions.
(Sec. 5) Directs the Foundation and any successor or related entity to the U.S. Russia Investment Fund (as defined by this Act) to enter into a memorandum of understanding for the purpose of coordinating activities carried out by the Foundation and the successor or related entity.
(Sec. 6) Defines "countries of Eurasia" as Armenia, Azerbaijan, Belarus, Georgia, Kazakhstan, the Kyrgyz Republic, Moldova, the Russian Federation, Tajikistan, Turkmenistan, Ukraine, and Uzbekistan.
(Sec. 7) Authorizes FY2008-FY2009 appropriations.


text:
Large hail stones smashed the Sunshine Coast as a line of storms moved across south-east Queensland.
A storm warning for the south-east was cancelled about 3.30pm, but not before hail and damaging wind struck coastal areas.
Earlier, the bureau reported ''tennis ball sized hail'' at Buderim, with large hail also reported at Mooloolah and Maroochydore.
Two of these are not like the others. Seen bucketing down on Qld's Sunshine Coast today. Pic by @HigginsStormCh pic.twitter.com/nOVbdc8wjg— ABC News (@abcnews) November 16, 2013
''Very dangerous thunderstorms were detected on weather radar near Maroochydore, the area between Boonah and Beaudesert and waters off Maroochydore,'' the bureau said.
''These thunderstorms are moving towards the east to north-east.''
Large hail picked up in Maroochydore this hour. Pic: Peter Angelo #qldstorm #bnestorm pic.twitter.com/vWOcKLmKOB— QPS Media Unit (@QPSmedia) November 16, 2013
"Very dangerous" thunderstorms were moving eastwards and were expected to affect Jacobs Well and Russell Island by 2.45pm..


text:
We stock a great selection of Dog Travel for Greyhounds.
Most of the Dog Travel below work well for the typically sized Greyhound.
We're happy to help! Click the "Help" button to your left for assistance in finding the perfect Dog Travel for your Greyhound! Plus, with our 365 day return policy, you can shop with confidence!


text:
Celebration of Motherhood
Healthy Start Coalition of Orange County
Thursday, May 8, 2014 from 8:00 AM to 10:00 AM (EDT)
Who's Going
San Francisco, California
London, United Kingdom
Florence, Italy
Event Details
Please join us for our annual Celebration of Motherhood Breakfast Fundraiser. Registration begins at 8:00am, and the event is from 8:30am-10:00am. Breakfast will be served, and there will be a silent auction.
Sarah Sprinkel, former director of Early Childhood Orange County Public Schools, is this year's guest speaker. The event concludes by honoring and recognizing mothers who were nominated for the role they fulfill as a mother.
When & Where
The Citrus Club
255 South Orange Avenue
Thursday, May 8, 2014 from 8:00 AM to 10:00 AM (EDT)
Add to my calendar
Healthy Start Coalition of Orange County
The Healthy Start Coalition of Orange County's mission is to improve maternal and child health in Orange County through community partnerships. Our vision is to be the leader in maternal and child health to ensure that all babies have a "healthy start." For more information about Healthy Start and other programs and classes offered, visit us on our website www.healthystartorange.org.


text:
The latest news in the Bollywood entertainment industry are related to the eviction Seema Parihar from the house of Bigg Boss. She and Sameer Soni and Khali were nominated to go from the reality show, but in the end the audience decided on her. However, anyone can say that Seema did play the game quit well, considering that she managed to stay in the show for quite a long time.
Probably the main reason for her long participation was the fact that she had an honest conduct and managed to era a large number of votes. Even though she does not possess a glam factor she impresses everybody thanks to her polite behavior.
During the evolution of the show, Seema was the only one who could have a good relationship with every member of the house. She even managed to have a good report with Shweta Tiwari. But how everything has to come to an end so did her participation in the Bigg Boss House. Now everyone is curious who will go next.


text:
To The Editor:
Does the data support the marketing plan?
I would like to compliment the Washington School District on its marketing approach to passing a tax increase on to all the residential, commercial and industrial real estate and personal property owners.
A demographic study was completed in 2011 (137 pages), at the request of the school district, which states, "A slight rebalancing of the enrollment through adjusting attendance lines would help with elementary school issues"; "just redrawing the boundary lines slightly could rebalance the enrollment at the elementary schools to ease whatever crowding issues might cropup."
Instead we get trailers and the reasoning that changing boundary lines would require longer bus rides and larger transportation costs. Really taking all of the sixth- to eighth-grade students four miles east of the central location in Washington, to the new campus on St. John's Road isn't going to affect many more students with longer bus rides?
Larger transportation costs are not only going to be for the school district but the families. They will be closing elementary schools which are now handy to their neighborhoods and possibly closing the smaller schools because they have taken away their sixth grade; Labadie had only 107 students in 2012.
According to DESE, Department of Elementary and Secondary Education, except for South Point (+ seven students), Washington West (+ six) and Campbellton (+ three), the elementary schools, middle school and high school decreased in attendance in 2012. The district was down nearly 100 students from the previous year's enrollment. There were only 88 pre-k students district wide in 2012.
Many of the taxpayers don't have school-age children. Thirty-two percent (32) send their children to private schools, homeschool or other public schools. They will be paying even more for a system they don't access. The U.S. Census Bureau reported a decrease in Franklin County's population for 2012.
Schools are the heart of every community. Technology and updating existing school buildings is obviously necessary. We have great teachers! Let's follow the demographic study, adjust attendance lines, get rid of trailers and use the space we already have available.
Please reference the Washington School District website for the demographic study, DESE website and U.S. Census article in the Weekend Missourian March 16-17.
Editor's Note: Name withheld per request.


text:
Recent Posts
Tuesday, March 6, 2012
Next month, perfumer Frederic Malle will release limited edition travel spray cases in collaboration with shoe designer Pierre Hardy. A "total of 500 of the individually hand sprayed cases will be sold within the US exclusively at the Frederic Malle NY Boutique, Barney's New York and Beverly Hills for $285 beginning in April." The cases are designed to hold Frederic Malle's 10ml sprays, sold separately.
Frederic Malle [official site]
Frederic Malle Travel Spray Cases [Now Smell This]
2 comments:
- littlebadwolf said...
what? now we're supposed to schlepp our lampshades to parties in custom airbrushed
cases like our bitch aunts used to drag their wigs around in? and our bitch great aunts
did with their hats?
i think once in central florida i saw a storefront-ful of custom airbrushed caskets, but it was the other way from disney.
- March 7, 2012 at 5:15 AM
- Alcira Molina-Ali said...
I love all of Malle's products, alas, a bitter taste was left in my mouth when, as a young and impressionable journalist I interviewed him in Paris at his Rue de Grenelle boutique. As soon as he saw I was a young American he became condescending, patronizing, rude -- everything one would expect from someone who squeezed a career off the shoulders of great ancestors who created some of the most legendary fragrances in the world.
It was a shame, because I was so in love with the whole Editions de Parfum concept and the experience burned a hole in that somehow.
Perhaps next time Monsieur Malle would do well to show a little noblesse oblige rather than behaving like a nouveau aristo.
Cheers, Alcira
- March 8, 2012 at 10:43 AM


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Our flight was canceled do to engine maintenance? Had to switch planes terminals. What a start! Once we landed in Jamaica we were the last to exit the plane because my wife had a walker which was loaded first. This made us the last people...More
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Veterans Health Administration
MOVE! to a New You in 2012
Men and women learn to incorporate excercise in their daily routine in the MOVE! program at the Maryland VA Medical Center.
VA's MOVE! program has helped hundreds of Veterans lose weight and start living a healthy life style.
Here's a whole bunch of success stories to inspire you.
We know you are facing the holiday season with all those parties and all that food.
Here are some great suggestions from MOVE! to get you through the end of the year.
Special occasions such as parties, celebrations, or holiday meals can pose risks for overeating.
Consider the weight loss you have achieved so far and what you have done to get to this point. Is splurging really worth it?
Avoid drinking alcoholic beverages as they are empty calories and make it harder for you to avoid temptation.
Be prepared.
Eat a small meal or snack before the special occasion so that you are less hungry.
Fill up ahead of time on water or other low calorie beverages.
Don't deny yourself.
Go ahead and have a taste of those special foods, but limit your portion sizes. Eat these special foods slowly and enjoy every morsel.
Choose low calorie munchies such as crunchy vegetables for balance.
Keep your hands and mouth occupied.
Focus on the conversation and having a good time rather than the eating. Get out on the dance floor! Chew gum.
Keep a glass in your hand containing a low calorie drink. It is hard to overeat if your hands are busy.
Great! You made it to 2012!
Now, visit your VA Medical Center today and sign up for the MOVE! program.
MOVE! has been tailored to meet the individual needs of each Veteran. MOVE! provides guidance on nutrition and physical activity and allows you to set the pace through goal setting and a stepped level approach.
The MOVE! health care team at your local VA medical center will provide you with lots of support and follow-up. Happy, healthy New Year!


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The Story of Fatima, Portugal
The Blessed Virgin Mary, the Mother of God, appeared 6 times to 3 sheperd children; Lucia, Francisco, and Jacinta; between May 13 and October 13, 1917. She came to the little village of Fatima which had remained faithful to the Catholic Church during the recent persecutions by the government. Our Lady came with a message from God to every man, woman, and child of our century. Our Lady of Fatima promised that the whole world would be in peace, and that many souls would go to Heaven if Her requests were listened to and obeyed. She told us that war is a punishment for sin; that God would punish the world for its sins in our time by means of war, hunger, persecution of the Church and persecution of the Holy Father, the Pope, unless we listened to and obeyed the command of God. At Fatima, Pope John Paul II said on May 13; " the message of Fatima is more relevant and more urgent " then when Our Lady first appeared. The message is an anguished appeal of our Heavenly Mother, Who sees us in great danger and Who comes to offer Her help and advice. Her message is also a prophesy, a clear indication of what was about to transpire in the 20th century, and what is still going to happen infallibly in the near future, depending on our response to Her requests.
As a great sign of the whole message truly coming from God, a marvelous miracle was worked in the sky above Fatima before 70,000 witnesses on October 13, 1917 at the time, date and place that Lucy and the other two children had prophesized in the name of Our Lady of Fatima. The children were told by Our Lady that God would perform a miracle so that people would believe in the apparitions. The date the children was October 13, 1917, in Fatima. On that date, 70,000 people came to see the phenomenon. The miracle occurred with the sun. All could stare perfectly at the sun without blinking, or even hurting heir eyes. While all were watching the sun, it rotated, got large and small, got close to the people, and got far away from them. The sun " danced ". Every single person who was there testified to seeing the sun dance, even non- believers who immediately dropped onto their knees and begged for forgiveness.
MIRACLES TODAY Our Lady of Fatima continues to work miracles today through Fatima water which is sent from Fatima, Portugal around the world. This Fatima water sprang up in Fatima at the spot the Bishop told people to dig, very near where Our Lady appeared at the Cova de Iria (the Cove of Peace) in Fatima. The water is known to cure people with sicknesses and poor health. Still, other people are cured when they go on pilgrimage to Fatima, which is about 90 miles north of Lisbon, Portugal.
If we do not heed Our Lady's warnings soon, Her horrible prophesy may well be realized in the near future, even in our own back yards. She told us that God had chosen to use Russia as the instrument of chastisement to punish the whole world if we did not, by our obedience, prayers, and sacrifices, obtain conversion of Russia to the Catholic faith. She promises us: " If my requests are granted, Russia will be converted and there will be peace. " But She also warned us: " If My requests are not granted, Russia will spread her errors throughout the world raising up wars and persecutions against the Church, the good will be martyred, the Holy Father will have much to suffer, various nations will be annihilated. " She has told us that the whole world (the part surviving) will be enslaved by the atheistic tyrants of Russia.
(Medjugorje, a small Croatian farming village nestled in the hills of Herzegovina (its name translates to "between the mountains"), was first mentioned historically in 1599. The current parish of Medjugorje was founded in 1892, pastored by Croatian Franciscan friars and dedicated to the apostle St James the Greater, patron saint of pilgrims. The current church building replaced the original church in 1969, to accommodate parishioners from the five local villages, which make up the parish of Medjugorje.
One of these villages, Bijakovici, is situated along the base of a rocky hillside that borders the fertile valley. This tiny hamlet of stone houses is home to the six children who, in the summer of 1981, experienced something that would change their lives and their Parish forever. On the evening of June 24, 1981, Feast of St. John the Baptist, around 6:00 pm two teenage girls named Ivanka and Mirjana were walking near the outskirts of their vil1age when they noticed the figure of a beautiful young woman holding an. infant in her arms, standing among the rocks and bramble on the hillside. She did not speak but gestured for them to come closer. Some other children alerted by the girls also saw the vision. The children were surprised and frightened and ran home, although they immediately thought the woman to be the Blessed Virgin. Mary.
On the following evening, June 25th, six of the children returned to the spot. They were Ivanka Ivankovic, Mirjana Dragicevic, Vicka Inabkovic, Ivan Dragicevic, Marija Pavlovic and Jakov Colo ages 10 - 16. Their families and others who had heard of the experience followed them. Upon reaching the place, they saw a flash of light, and looking up the hillside, saw Our Lady, this time without the child. She was smiling, joyful and indescribably beautiful. She gestured with her hands for them to come closer and when they came before her, the children immediately knelt and began to pray with Our Lady. She spoke with the children and telling them not to be afraid, introducing Herself as the Queen of Peace. On the evening of June 26th, the children sprinkled holy water onto the vision saying "If you are the Blessed Mother please stay but if you are not go away from us.". At this Our lady smiled and stayed. Since then, many have come to the village, both believers and skeptics. The children and priests underwent many trials and tests, especially from the communist government, but Our Lady remained, to bring hope and peace to the world through the six village children who were the first to respond to her call)..
|Fatima Tours (requires Internet connection)


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iCore initiative addresses two key issues in the context of the Internet of Things (IoT), namely how to abstract the technological heterogeneity that derives from the vast amounts of heterogeneous objects, while enhancing reliability and how to consider the views of different users/stakeholders (owners of objects & communication means) for ensuring proper application provision, business integrity and, therefore, maximize exploitation opportunities.
The iCore proposed solution is a cognitive framework comprising three levels of functionality,reusable for various and diverse applications. The levels under consideration are virtual objects(VOs), composite virtual objects (CVOs) and functional blocks for representing the user/stakeholder perspectives.
VOs are cognitive virtual representations of real‐world objects (e.g. sensors, devices, everyday objects) that hide the underlying technological heterogeneity. CVOs, on the other hand are cognitive mash‐ups of semantically interoperable VOs, delivering services in accordance with the user/stakeholder requirements. The iCore solutions will be equipped with essential security protocols/functionality, which span all levels of the framework, and consider the ownership and privacy of data, as well as controlling the actual access to objects. To validate the proposed solutions iCore addresses the following usecases: ambient assisted living, smart office, smart transportation, and supply chain management.


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Dietary habits influence the risk of cancer of the oesophagus and oesophago-gastric junction, but the role of proportions of the main dietary macronutrients carbohydrates, fats and proteins is uncertain.
Data was derived from a nationwide Swedish population-based case-control study conducted in 1995–1997, in which case ascertainment was rapid, and all cases were uniformly classified. Information on the subjects' history of dietary intake was collected in personal interviews. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated using logistic regression, with adjustment for potentially confounding factors.
Included were 189 oesophageal adenocarcinomas, 262 oesophago-gastric adenocarcinomas, 167 oesophageal squamous cell carcinomas, and 820 control subjects. Regarding oesophageal or oesophago-gastric junctional adenocarcinoma, a high dietary proportion of carbohydrates decreased the risk (OR 0.50, CI 0.34–0.73), and a high portion of fat increased the risk (OR 1.96, CI 1.34–2.87), while a high proportion of protein did not influence the risk (OR 1. 08, 95% CI 0.75–1.56). Regarding oesophageal squamous cell carcinoma, the single macronutrients did not influence the risk statistically significantly.
Citation: Lagergren K, Lindam A, Lagergren J (2013) Dietary Proportions of Carbohydrates, Fat, and Protein and Risk of Oesophageal Cancer by Histological Type. PLoS ONE 8(1): e54913. https://doi.org/10.1371/journal.pone.0054913
Editor: Manlio Vinciguerra, Foundation for Liver Research, United Kingdom
Received: October 1, 2012; Accepted: December 18, 2012; Published: January 22, 2013
Copyright: © 2013 Lagergren et al. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Funding: Funding was provided by the Swedish Research Council (ID 80749601; http://www.vr.se/inenglish.4.12fff4451215cbd83e4800015152.html). The funder had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.
Competing interests: The authors have declared that no competing interests exist.
Oesophageal cancer is characterised by a poor prognosis (the 5-year survival rate is less than 10%) and a high incidence (the 8th most common cancer globally) [1]. Squamous cell carcinoma is the dominating histological type in non-industrialised countries, but its incidence has decreased in industrialised countries [2]. The incidence of adenocarcinoma of the oesophageal and oesophago-gastric junction, on the other hand, has increased rapidly in Western populations, [3] and currently adenocarcinoma is more common than squamous cell carcinoma in several industrialised populations, particularly in white men [2]. The main risk factors for oesophageal squamous cell carcinoma in industrialised countries are tobacco smoking and alcohol abuse, while adenocarcinoma is mainly associated with gastro-oesophageal reflux and obesity [4]. Moreover, dietary habits have been associated with risk of both histological types of oesophageal cancer. A high dietary intake of fruit (antioxidants), vegetables and fibre is associated with a decreased risk of adenocarcinoma and squamous cell carcinoma of the oesophagus, while a diet high in fat and meats, particularly red meats, seems to be associated with an increased risk of these tumours [5]–[9]. Several other dietary items and patterns have been found to possibly influence the risk of oesophageal cancer, but the current evidence is more limited. No study has addressed how the proportions of the main dietary nutrients, i.e. carbohydrates, protein, and fat, influence the risk of these tumours. Therefore, this study aimed to reveal associations between the proportions of the three main dietary nutrients and the risk of developing oesophageal cancer by histological type.
Ethics statement
All participants provided both written and verbal informed consent to participate in this study. The study was approved by all six regional ethics committees in Sweden, i.e. The Regional Ethical Review Board in Stockholm, The Regional Ethical Review Board in Uppsala, The Regional Ethical Review Board in Umeå, The Regional Ethical Review Board in Linköping, The Regional Ethical Review Board in Göteborg and The Regional Ethical Review Board in Lund.
Study design
The design and organisation of this population-based and nationwide Swedish case-control study have been described in detail elsewhere, [10] and the aetiological roles of reflux, body mass, tobacco smoking, alcohol consumption, and infection with Helicobacter pylori for oesophageal and oesophago-gastric junctional cancer have been evaluated in this case-control study [10]–[13]. In brief, cases and controls were prospectively included and data collected in 1995 to 1997. The study base was the entire Swedish population aged below 80 years. All newly diagnosed cases of adenocarcinoma of the oesophagus and oesophago-gastric junction, and half of the cases of squamous cell carcinoma of the oesophagus (those born on even numbered dates) were eligible as cases. The reason for including only half of the squamous cell carcinoma cases was that this cancer type was more common in Sweden during the study period, and the main focus of the study was on adenocarcinoma. Population-based control subjects were randomly selected from 10-year age and gender strata in the entire Swedish population. The controls were frequency-matched regarding age and sex to the cases of oesophageal adenocarcinoma.
Assessment of nutrient proportions
All case patients and control subjects were personally interviewed by professional interviewers from Statistics Sweden to provide data on background variables and various exposures, including a detailed food frequency questionnaire. The interviewers could not be blinded to the case/control status of the interviewees, but they were unaware of the study hypothesis and were urged to treat the cases and controls in a strictly equal manner. This food frequency questionnaire used was adopted from a validated standard questionnaire, which has been found to have high validity and reproducibility regarding assessment of dietary patterns [14], [15]. The information from the food frequency questionnaire was used to assess the relative proportions of the three main dietary components, i.e. carbohydrates, protein, and fat, of each study participant. The exposure data was based on a selected set of items regarding food and beverages, and we calculated the number of grams of carbohydrates, protein, and fat for each of the included items. To do this, we calculated the frequency of the consumption of each item and multiplied it by the average portion size. The portion sizes were assessed by the measures given by the Swedish National Food Administration. Thereafter, we calculated how many grams of carbohydrates, protein, and fat that each subject consumed per month by multiplying one hundred grams of the food or drink variable by how much each dietary item contained per 100 grams. The total consumption of carbohydrates, protein and fat was then transformed to energy intake in calories (1 gram carbohydrates = 4000 calories, 1 gram protein = 9000 calories and 1 gram fat = 7000 calories). The total monthly energy intake was then estimated for each participant and the proportion of carbohydrates, protein and fat of the monthly energy intake calculated. The proportions of intake of carbohydrates, protein, and fat were first grouped into quartiles based on the consumption among the control subjects, i.e. the cut-offs in 4 exposure groups of each of the 3 nutrient groups were based on 4 equally sized groups of control subjects. Finally, the relative distribution of all three macro nutrients was categorised into 6 groups. These 6 groups were created on the basis of a cut-off of the median consumption among the control subjects as high or low in each of the components: 1) a diet high in carbohydrates (≥48% of the total), low in protein (<37%) and low in fat (<24%) (reference category), 2) a diet high in carbohydrates (≥48%), high in protein (≥37%) and low in fat (<24%), 3) a diet high in carbohydrates (≥48%), low in protein (<37%) and high in fat (≥24%), 4) a diet low in carbohydrates (<48%), high in protein (≥37%) and low in fat (<24%), 5) a diet low in carbohydrates (<48%), low in protein (<37%) and high in fat (≥24%), and 6) a diet low in carbohydrates (<48%), high in protein (≥37%) and high in fat (≥24%).
Assessment of cancer cases
All 195 Swedish hospital departments involved in the diagnosis or treatment of oesophageal cancer patients collaborated in the recruitment of cases. The six regional tumour registries enabled us to identify missing cases. There was a protocol for uniform documentation and classification of the tumours. At endoscopy, the distances between the oesophago-gastric junction (defined as the point where the proximal longitudinal mucosal folds begin in the stomach) and the upper and lower borders of the tumour, were measured. The protocol also prescribed that serial biopsy specimens should be taken every 2 cm from the proximal stomach, through the oesophago-gastric junction, in the oesophagus, until normal squamous-cell epithelium was reached. Additional specimens were to be obtained proximally, distally, and laterally to the tumour. Surgeons and pathologists completed standardised and detailed descriptions of the location of the cancer in operated cases. Moreover, 97% of all biopsies and surgical specimens were re-examined by one pathologist. An adenocarcinoma of the oesophago-gastric junction had to have its centre within 2 cm above, or 3 cm distal to the junction. If Barrett´s oesophagus was detected adjacent to the tumour, [16] it was classified as oesophageal, irrespective of its location.
Statistical analysis
Unconditional logistic regression was used to analyse the exposures as continuous variables in relation to risk of the studied tumours and to analyse defined exposure categories as presented above, providing crude and adjusted odds ratios (OR) with 95% confidence intervals (95% CI). The cases in each cancer category were first compared with all controls, and in a second analysis, cases of adenocarcinoma of the oesophagus or oesophago-gastric junction were analysed jointly. In crude models, no adjustments were made, but the frequency matching provided similar distribution of age and sex. In the multivariable model, the results were adjusted for age, sex, reflux symptoms (heartburn or regurgitation at least once a week occurring at least 5 years before the interview, yes or no), body mass index (categorised into four groups from high to low by quartiles among the control subjects), tobacco smoking (never-, previous- or current smokers 2 years before the interview), alcohol use (grams of pure alcohol categorised into four groups from high to low by quartiles among the control subjects), years of formal education (>12 years, 7–12 years, or <7 years), and total energy intake (categorised in quartiles based on the consumption of the control participants).
Study participants
The study included 189 cases of oesophageal adenocarcinoma (87% participation rate), 262 cases of oesophago-gastric adenocarcinoma (86% participation rate), 167 cases of oesophageal squamous cell carcinoma (73% participation rate), and 820 control subjects (73% participation rate). Characteristics of the participating case and control subjects are presented in Table 1. The median ages ranged from 66 to 69 years in the four groups of participants. There was an expected male predominance. Tobacco smoking and alcohol drinking were most common among the cases of oesophageal squamous cell carcinoma, while reflux and obesity were most common among the cases of oesophageal adenocarcinoma (Table 1).
Risk of oesophageal adenocarcinoma
High proportions of consumption of carbohydrates were followed by a possibly decreased risk of oesophageal adenocarcinoma (Table 2). The model with continuous exposure showed an adjusted OR of 0.77 (95% CI 0.58–1.03) per 10% increase in proportion of carbohydrates of total energy intake. Subjects in the highest quartile of the proportion of carbohydrates consumption were at a possibly decreased risk compared to those in the lowest quartile of consumption (adjusted OR 0.68, 95% CI 0.40–1.16). A correspondingly high proportion of consumption of protein did not influence this risk (adjusted OR 0.86, 95% CI 0.51–1.45). The highest quartile of proportion of fat intake indicated an increased risk of oesophageal adenocarcinoma compared to a low proportion of fat intake (adjusted OR 1.82, 95% CI 1.07–3.10), and a 10% increase in proportion of fat showed an adjusted OR of 1.65 (95% CI 1.07–2.55). Compared to a diet high in carbohydrates and low in both protein and fat, a diet low in carbohydrates and high in protein and fat (adjusted OR 1.46, CI 0.90–2.37), a diet low in carbohydrates, low in protein and high in fat (adjusted OR 1.68, CI 0.85–3.32), and a diet low in carbohydrates, high in protein and low in fats (adjusted OR 1.46, CI 0.71–3.00), were followed by a possibly increased risk of oesophageal adenocarcinoma, but the results were not statistically significant (Table 2).
Risk of oesophago-gastric junctional adenocarcinoma
A high proportion of carbohydrate intake (highest quartile) was associated with a more than halved risk of oesophago-gastric junctional adenocarcinoma compared to a low proportion (adjusted OR 0.41, 95% CI 0.26–0.66) (Table 3). 10% increase in the proportion of carbohydrates showed an adjusted OR of 0.73 (95% CI 0.58–0.92). The proportions of protein consumption did not influence this risk. A high fat proportion intake increased the risk, and those who consumed protein in the highest quartile were at a 2-fold increased risk of oesophago-gastric junctional adenocarcinoma compared to those in the lowest quartile (adjusted OR 2.10, 95% CI 1.33–3.32), with a 10% increase corresponding to an OR of 1.62 (95% CI 1.14–2.30) in the model with continuous exposure. A diet with a low proportion of carbohydrates and a high proportion of both fat and protein increased the risk by over 50%, compared to a diet with a high proportion of carbohydrates and low proportions of protein and fat (adjusted OR 1.57, 95% CI 1.05–2.35) (Table 3).
Risk of oesophageal or oesophago-gastric junctional adenocarcinoma
Since oesophageal and oesophago-gastric junctional adenocarcinomas are closely located and share many characteristics and aetiological factors, these tumours were combined in an analysis to increase statistical power. A high proportion of carbohydrates decreased the risk of these tumours (adjusted OR 0.50, CI 0.34–0.73), while a high proportion of fat increased the risk nearly 2-fold (adjusted OR 1.96, CI 1.34–2.87) (Table 4). A high proportion of protein seemed not to influence the risk of oesophageal or oesophago-gastric junctional adenocarcinoma (adjusted OR 1.08, CI 0.75–1.56). These results were supported by the model with continuous exposure (Table 4). Compared to a diet high in carbohydrates and low in both protein and fat, a dietary distribution low in carbohydrates, low in protein and high in fat (adjusted OR 1.73, CI 1.09–2.75), a diet low in carbohydrates, high in protein and low in fat (adjusted OR 1.69, CI 1.03–2.79), and a diet low in carbohydrates, high in protein and high in fat (adjusted OR 1.51, CI 1.07–2.12) increased the risk of these tumours (Table 4).
Risk of oesophageal squamous cell carcinoma
The proportions of consumption of carbohydrates did not influence the risk of oesophageal squamous cell carcinoma (Table 5). Participants in the highest proportion quartile of carbohydrates had no decreased risk of this cancer compared to those in the lowest quartile (adjusted OR 1.05, 95% CI 0.61–1.80). Higher proportions of protein consumption were followed by a tendency towards an increased risk, but not statistically significantly (Table 5). The highest quartile of proportion of fat consumption indicated a possibly decreased risk of oesophageal squamous cell carcinoma compared to the lowest quartile (adjusted OR 0.73, 95% CI 0.42–1.27),and a diet distribution low in carbohydrates, low in protein, and high in fat entailed a decreased risk compared to a diet high in carbohydrates, low in fat and low in protein (adjusted OR 0.32, 95% CI 0.12–0.81). No statistically significant associations were found when the macronutrients were analysed as continuous variables (Table 5).
Generally, the crude ORs were similar to the fully adjusted ORs (Tables 2, 3, 4, 5).
This study indicates that a high proportion of carbohydrate consumption of the total energy intake decreases the risk of oesophageal and oesophago-gastric junctional adenocarcinoma, whereas a high proportion of fat in the diet increases the risk of these tumours, and proportions of protein consumption do not influence this risk. These nutrient proportions did not clearly influence the risk of oesophageal squamous cell carcinoma.
Strengths of the study include the population-based design with high participation rates, the thorough and uniform classification of all tumours, the ability to adjust the results for all established risk factors, and the complete and rapid case ascertainment, which enabled personal interviews with all participants. Among weaknesses is the misclassification of the exposure, which might be increased by the fact that we asked about dietary habits 20 years prior to interview. This method of assessment of dietary items 20 years earlier has, however, been validated with good results, showing that such assessment captures a combination of previous and current dietary habits [17]. Moreover, the exposure misclassification should be non-differential, i.e., similar between cases and controls, and thus the true risk estimates are probably underestimated as a result of dilution [18]. The assessment of nutrient proportions based on food frequency questionnaires might be a rough method prone to misclassification, but it is still the most validated and used measure of such exposures. Another concern is whether the assessment of proportions in relation to risk of oesophageal cancers actually measures the influence of proportions, or whether it is just an effect of specific carcinogenic dietary items within these groups of nutrients. Nevertheless, the diverging results for adenocarcinoma and squamous cell carcinoma indicate a role of proportions. These diverging findings also indicate that recall bias might not be a major issue, which is otherwise a threat to case-control studies with data collected from interviews. Finally, chance error cannot be excluded. There were a relatively small number of cases in each tumour group, which limited the precision. Moreover, the many comparisons conducted might introduce multiple testing errors.
Recent studies have provided further evidence that fruit and vegetable intake is associated with decreased risk of oesophageal and oesophago-gastric junctional adenocarcinoma and oesophageal squamous cell carcinoma, whereas meat and nitrate decreases the risk of these tumours [5]–[8], [19], [20]. A diet rich in foods of animal origin and poor in foods containing vitamins and fibre increases the risk of oesophageal cancer in general [5]. Moreover, a high-fat diet is associated with increased risk of both oesophageal cancer and junctional adenocarcinoma. Higher intake of meat, particularly red meat, is associated with an increased risk of oesophageal adenocarcinoma, while higher intake of meats such as poultry, and high-fat diary is associated with increased risk of junctional adenocarcinoma [19]. While previous studies have typically focused on the food items themselves or on other dietary patterns, this study addressed the role of proportions of energy intake between the macro nutrients carbohydrates, fats, and proteins in relation to oesophageal cancers. Most previous studies have found similar patterns of association between dietary factors and adenocarcinoma and squamous cell carcinoma of the oesophagus, but the differences in patterns found between the histological types in this study of macro nutrient proportions seem to indicate separate dietary aetiologies. The fat proportion in particular seemed to influence the risk of adenocarcinoma and squamous cell carcinoma of the oesophagus in opposite directions.
The oesophageal cancer specific mechanisms that might explain the findings of the present study can only be speculated upon. A high fat proportion might be followed by an increased prevalence of obesity, which in turn entails an increased risk of adenocarcinoma of the oesophagus and oesophago-gastric junction, but the results of the present study were thoroughly adjusted for the influence of BMI. Residual confounding by BMI cannot be entirely excluded, but alternative mechanisms should be considered. A high fat proportion diet might cause a slower passage of food through the stomach, i.e. inhibition of gastric emptying by intestinal peptides, [21] which in turn might result in an increased occurrence of gastro-oesophageal reflux. Although reflux symptoms were adjusted for in the analysis, an increased occurrence of asymptomatic (physiological) reflux cannot be dismissed as an explanation for the finding. The lack of any increased risk of oesophageal squamous cell carcinoma among a proportionally high-fat dietary pattern would support this hypothesised mechanism, since this cancer is not associated with reflux. The seemingly beneficial effects of a high dietary carbohydrate proportion specific to oesophageal and junctional adenocarcinoma would probably not be through high consumption of fruit and vegetables, since such consumption is at least as protective for squamous cell carcinoma of the oesophagus. A high proportion of carbohydrates might simply reflect a low proportion of fat, which in turn seems beneficial.
In conclusion, this population-based and nationwide Swedish study indicates that a high proportion of consumption of carbohydrates decreases the risk for oesophageal and oesophago-gastric junctional adenocarcinoma, while a high proportion of consumption of fat increases the risk and protein proportions did not influence this risk. Macro nutrient proportions did not much influence the risk of oesophageal squamous cell carcinoma. These differences indicate some separate dietary aetiology for the main histological types of oesophageal cancer.
Author Contributions
Conceived and designed the experiments: KL JL. Performed the experiments: KL AL JL. Analyzed the data: AL. Wrote the paper: KL JL. Critically revised the manuscript for important intellectual content: KL AL JL.
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- 13. Ye W, Held M, Lagergren J, Engstrand L, Blot WJ, et al. (2004) Helicobacter pylori infection and gastric atrophy: risk of adenocarcinoma and squamous-cell carcinoma of the esophagus and adenocarcinoma of the gastric cardia. J Natl Cancer Inst 96: 388–396.
- 14. Khani BR, Ye W, Terry P, Wolk A (2004) Reproducibility and validity of major dietary patterns among Swedish women assessed with a food-frequency questionnaire. J Nutr 134: 1541–1545.
- 15. Levitan EB, Westgren CW, Liu S, Wolk A (2007) Reproducibility and validity of dietary glycemic index, dietary glycemic load, and total carbohydrate intake in 141 Swedish men. Am J Clin Nutr 85: 548–553.
- 16. Sharma P (2009) Clinical practice. Barrett's esophagus. N Engl J Med 361: 2548–2556.
- 17. Wolk A, Bergstrom R, Hansson LE, Nyren O (1997) Reliability of retrospective information on diet 20 years ago and consistency of independent measurements of remote adolescent diet. Nutr Cancer 29: 234–241.
- 18.
Rothman KJ (2002.) In: Rothman KJ, editor. Epidemiology: An introduction Oxford University Press. 95–112.
- 19. Navarro Silvera SA, Mayne ST, Risch H, Gammon MD, Vaughan TL, et al. (2008) Food group intake and risk of subtypes of esophageal and gastric cancer. Int J Cancer 123: 852–860.
- 20. Terry P, Lagergren J, Hansen H, Wolk A, Nyren O (2001) Fruit and vegetable consumption in the prevention of oesophageal and cardia cancers. Eur J Cancer Prev 10: 365–369.
- 21. Karhunen LJ, Juvonen KR, Huotari A, Purhonen AK, Herzig KH (2008) Effect of protein, fat, carbohydrate and fibre on gastrointestinal peptide release in humans. Regul Pept 149: 70–78.


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Best Of :: Food & Drink
Working your way through the six salsas at Jarro Cafe is like taking a master class on the Scoville scale. The offerings range from eye-opening (the chunky oregano and chile-accented onion salsa) to sneaky-hot (the sweetened chile arbol paste) to volcanic (the bright green tomatillo-serrano slurry). Beneath the heat lurk complex flavor profiles, perfectly matched to the peerless Mexico City-style fare turned out by Memo Pinedo's kitchen. Not for nothing has this Spring Branch favorite already been written up this year in both The New York Times and Texas Monthly. It's also the perfect place to test the mettle of visiting guests who claim they like to eat spicy food.
Los Dos Amigos holds court with other old souls Wabash Feed Store, Guadalajara Bakery and Laredo Taqueria as reminders of Washington Avenue's not-so-distant past, and it's held on this long for good reason: The food, especially the enchiladas, seems to get better the longer Los Dos sticks around. And the gooey, surprisingly greaseless cheese enchiladas with a fried egg on top are the best dish here, available on the dinner menu even though most people order them for breakfast. Kicked up with a shot of the vinegar-based red sauce on each table, these enchiladas are truly the breakfast of champions.
The tequila selection alone at Hugo's — more than 40 choices, counting its bottles of mezcal — should indicate that you're in for a serious cocktail at this Mexican favorite. Sommelier Sean Beck dreams up exciting twists on the classic cocktail, like El Sueño Profundo with smoky mezcal, but it's the standard Hugorita for $7.50 that we like best. Created with Sauza Silver, Hiram Walker Triple Sec, simple syrup and fresh lime juice, it's mixed tableside. We also love the Y Porque No margarita for only $5 during its weekday happy hours.
One could argue that the real people-watching goes down in the valet drive that's shared by Philippe and its next door neighbor, RDG + Bar Annie. But the younger set always makes its way up Philippe's grand staircase, and that's where the pretty young thing-watching commences. Celebrities both local and national — think Robert Kardashian and Carolyn Farb — love this little slice of glitz and glamour in Houston, and especially love being seen with its handsome chef, the eponymous Philippe Schmit. But even regular schmoes like us can enjoy Philippe, too; the French-Texan menu is surprisingly affordable, as is its excellent wine list.
Southwestern cuisine stopped being hip in Houston somewhere around Cafe Annie's millionth year in existence, long before its closure last year. So imagine our surprise when TQLA swooped in with Southwestern vet Tommy Birdwell at the helm and made it cool again. (Of course, having 167 different varieties of tequila, many of them on tap, doesn't hurt either.) The updated Southwestern cuisine here incorporates Tex-Mex influences as well as our own Gulf Coast cuisine, and the result is a fresh, lively menu that features excellent dishes such as crawfish corncakes with lime butter and blue corn-fried oysters with chorizo cream.
The best salad in town at a place best known as a palace to pork, a monument to meat? Yes. And that's because Stella Sola treats its vegetables with as much care and love as it does its many proteins. The Dal Giardino salad — which translates to "from the garden" in Italian — epitomizes this attitude toward showcasing fresh, local produce. Seasonal lettuce and other vegetables, like curling tendrils of watercress, mingle with pickled carrots in a Meyer lemon vinaigrette that sings brightly through the greens. Its crowning glory? A farm-fresh poached egg, whose orange yolk mixes with the vinaigrette to create a pitch-perfect dressing.


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A Retrospective of Yves Klein Blue
Color Diary: Yves Klein Blue
I'm excited to present a story from one of my favorite sites, ShelterPop!
Named for the French artist obsessed with its pure qualities, Yves Klein Blue has been inspiring designers for decades.
There has to be something very special about a color if it inspires an artist to create an entire series of work around it. Such was the case with French artist Yves Klein who did exactly that with the eponymous color he created — Yves Klein Blue, also known as International Klein blue.
In the late 1950s he embarked on a series of monochromatic works and performances in which naked models were painted in the color and then used to mark canvases with their bodies. The rich, lapis-lazuli toned blue was the works' central theme. According to Gabriel Riera, Director of Communications for the Smithsonian Institute — where the Hirshhorn Museum is having a major retrospective of Klein's work until September 12th — Klein saw more to this breathtaking color than just a pretty shade of blue.
"The blue canvases acted as a starting-off point or gateway to Klein's real artwork, which represented the idea of a pure, expansive void," he says. This all stemmed from a spiritual experience Klein once had at the beach with friends, where he was enchanted by the vastness of the ocean and sky. "In person, the large blue canvases vibrate and the pure color almost jumps off the painting," says Riera. This unique effect is a result of the way this color is created. Ultramarine blue pigment is placed — not mixed — into a liquid binder, causing it to stay suspended. Riera adds, "The physical properties make the color hard to reproduce."
But that hasn't stopped people from loving and using it. In face, several other interior designers and architects have been enchanted with the color — using it in their clients' homes, as well as their own. New York City-based interior designer Miles Redd remembers his first experience with Yves Klein Blue. "The first time I ever became aware of Yves Klein was at age 10. GQ had done a fashion story inspired by the parties Klein used to throw, where he would paint models in cobalt blue. Everyone was blue and dressed in tuxedos and gowns. The color and images really fascinated me and I became curious about the artist."
Continue reading for more Yves Klein blue!
Redd has since used the color in several of his clients' homes — considering it a neutral of sorts. "It's such a strong, intense cobalt, yet it can be [used] in any room. The very nature of its strength makes other colors pop," he says. "I designed the hallway of a young Manhattan couple and lacquered the walls in Yves Klein Blue. Applying it as a lacquer really brought out the color's inherent luminosity and made it work with bold reds and other primaries." It can also bring a modern edge to a room. "That apartment was filled with very traditional Virginian brown furniture. The color made everything look young, fresh and ultimately timeless."
But what makes it so versatile and timeless? Interior designer Amie Weitzman has a theory and it relates to her background in fashion. "Basic menswear fabrics serve as the base of so many rooms that I design — gray flannel, a neutral brown tweed — they all are neutrals that go with everything." And what's the number one neutral in clothing? Denim. "You can wear denim with any color or any style and the finished look works," she says. She designed the room (at left) to serve as a cigar lounge for a music industry executive. "I wanted to take something really classic, like a simple tufted sofa in a cotton velvet, and make it really pop. That, combined with edgy contemporary art and turn-of-the-century wood paneling, created an interesting juxtaposition."
The color also helps to highlight a home's architectural elements. Architect Joe Serrins worked with photographer Annie Schlechter to create a sharp, clean dining room that included a freestanding blue wall (seen above). The color was really Schlechter's idea. "She suggested it, and by suggested, I mean she had a eureka moment and told me this was the only option." Luckily, the color complements the space. "It acts as an anchor and focal point for the room and as a beautiful background for the other vivid colors and furnishings."
Whether you use a little or a lot of it, in a modern or traditional room, this color will make a statement. And if history is any indicator, Yves Klein Blue will remain fresh and timeless for countless years to come.
The Yves Klein Blue retrospective is on display until September 12th.
Check out some more of my favorite stories from ShelterPop!


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Uganda - Diagnostic Trade Integration Study Update : Prepared for the Enhanced Integrated Framework
No abstract is available for this item.
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|Date of creation:
|Apr 2013
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Phone: (202) 477-1234
Web page: https://openknowledge.worldbank.org
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References listed on IDEAS
Please report citation or reference errors to , or , if you are the registered author of the cited work, log in to your RePEc Author Service profile, click on "citations" and make appropriate adjustments.:
- George J. Stigler, 1971. "The Theory of Economic Regulation," Bell Journal of Economics, The RAND Corporation, vol. 2(1), pages 3-21, Spring.
- Richard A. Posner, 1974.
"Theories of Economic Regulation,"
Bell Journal of Economics,
The RAND Corporation, vol. 5(2), pages 335-358, Autumn.
- Richard A. Posner, 1974. "Theories of Economic Regulation," NBER Working Papers 0041, National Bureau of Economic Research, Inc.
- Ole Boysen & Alan Matthews, 2009. "The Economic Partnership Agreement between Uganda and the EU: Trade and Poverty Impacts," The Institute for International Integration Studies Discussion Paper Series iiisdp307, IIIS.
- Ingo Borchert & Batshur Gootiiz & Aaditya Mattoo, 2014. "Policy Barriers to International Trade in Services: Evidence from a New Database," World Bank Economic Review, World Bank Group, vol. 28(1), pages 162-188.
- Borchert, Ingo & Gootiiz, Batshur & Mattoo, Aaditya, 2012. "Policy barriers to international trade in services : evidence from a new database," Policy Research Working Paper Series 6109, The World Bank.
- Paul Conway & Giuseppe Nicoletti, 2006. "Product Market Regulation in the Non-Manufacturing Sectors of OECD Countries: Measurement and Highlights," OECD Economics Department Working Papers 530, OECD Publishing.
- George A. Akerlof, 1970. "The Market for "Lemons": Quality Uncertainty and the Market Mechanism," The Quarterly Journal of Economics, Oxford University Press, vol. 84(3), pages 488-500. Full references (including those not matched with items on IDEAS)
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BT Financial Group has marked life insurance as one of its biggest growth opportunities, as the wealth giant aims to entice under-insured Australians onto its books.
"We don't have the legacy issues of others ... we don't underwrite any group life insurance," he argued.
Life insurers, particularly group life providers that sell policies through super funds, are under siege from skyrocketing claims, badly priced insurance policies and customers cancelling their cover .
"It was a very informed decision [not to go into group life]," Mr Cooper added. "Our plans are to continually upgrade the capability of our distribution advisers and bank managers."
Market share growth
BT controls 8.5 per cent or $685 million of the life insurance market when measured by in-force premiums. New sales market share have improved from just under 8 per cent to 10.5 per cent in the last three years.
New research from the Financial Services Council and KPMG showed that Australians are grossly under-insured for income protection, sparking a $304 billion insurance gap that could leave tens of thousands of people in the lurch if they suffered permanent disablement.
BT currently generates around $737 million or around 10 per cent of Westpac's group cash earnings. Mr Cooper is hoping to dial up the division's contributions to circa 15 per cent of the bank's cash earnings in the next five years.
"There's a much higher volatility in earnings in wealth compared with banking," Mr Cooper said about growing the wealth arm's contributions to the wider group.
Tapping into SMSF
BT is also eyeing the booming self-managed super fund sector which represents the fastest growing segment of Australia's $1.6 trillion superannuation industry.
One way BT is hoping to tap the growth of the sector stems from existing products and making a margin on investment options including managed accounts, property loans, managed funds and term deposits.
"Our group strategy for the last two years and probably for the next 18 months is much more around the product margin in the underlying investments," Mr Cooper said.
The first component of BT's NextGen investment platform is expected to be rolled out by March, and includes a cash hub that would be targeted towards self-managed super fund trustees.
The Australian Financial Review


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Trend Analysis with Value Breakdown reports null on graph using IBM Rational Change
Technote (troubleshooting)
When using the Reports function in Change 5.2, the value of NULL shows up in the label of the graph for Trend Analysis with Value Breakdown.
The null word shows in the graph.
This issue was identified as a product defect under APAR PM62150.
The defect is because the report application needs a new version of BIRT to resolve it (version 2.3.1). The inclusion of the fix can only be done at a full version release.
The defect is reported here:
IBM Rational Change Report Builder
Diagnosing the problem
The null value shows up in the Trend Analysis with Value Breakdown graph.
Resolving the problem
Requires running multiple reports to work around this issue.
Document information
More support for:
Rational Change
General Information
Software version: 5.2, 188.8.131.52, 22.214.171.124, 188.8.131.52, 220.127.116.11, 126.96.36.199, 126.96.36.199, 22.214.171.124, 5.3, 220.127.116.11, 126.96.36.199, 184.108.40.206
Operating system(s): Linux, Solaris, Windows
Reference #: 1615804
Modified date: 31 October 2012
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As this printing ink is of a greasy nature, it will leave the roller only for the lines of the design, which remain quite dry.
Bronze blue affords a striking example of a printing ink of this character.
Always object to a parcel being put up in newspaper, as the printing ink will rub off and soil the article enclosed.
It also has the power of conveying many of its own good qualities to any printing ink with which it may be incorporated.
Substitute for lithographic stone; a firm, black, copying, printing ink; method for photographing in colors.
Air-drying can only be accomplished by adding to the printing ink a proportion of some suitable drier.
Impressions may be taken from the plates formed in this way, by means of printing ink and the copper-plate press.
The ink employed in this kind of printing, is similar in its composition to other kinds of printing ink.
I just moved the molecules of pigment in the printing ink and reassembled them in the opposite cards.
Impressions may be taken from the plates formed in this way by means of printing ink and a copperplate press.


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Search Results
Title: The Kanawha Valley : its resources and developments ; also, special business directory of Charleston and other cities
Author: Gibbons, J.A.
Publication Info: Charleston, W. Va. : Gibbens, Atkinson & Co., Printers, 1872.
subjects: [Kanawha River Valley (W. Va.)--Economic conditions] [West Virginia--Description and travel]
Title: Resources of West Virginia
Authors: Maury, Matthew Fontaine, 1806-1873., West Virginia. State Board of Centennial Managers., Fontaine, William Morris, 1835-1913.
Publication Info: Wheeling : The Register Company, 1876.
subjects: [Centennial Exhibition (1876 : Philadelphia, Pa.)] [West Virginia--Economic conditions] [West Virginia--Description and travel]
Title: Sketch of western Virginia for the use of British settlers in that country.
Publication Info: London : Edward Bull, 1837.
subject: [West Virginia--Description and travel]
Title: The West Virginia hand-book and immigrant's guide : a sketch of the state of West Virginia ...
Author: Debar, Joseph Hubert Diss.
Publication Info: Parkersburg : Gibbens Bros., 1870.
subject: [West Virginia--Description and travel]


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Book clubs, cooking clubs, bunco, bridge…what is the unifying theme to most women's gatherings? Wine! If you can add in the opportunity to do...
FlipKey is a vacation rental marketplace with more than 240,000 rentals around the
world. Find the perfect place to stay for your trip, and get great value along with the
space, privacy and amenities of home.


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Click on the image to enlarge.
Size: 830 x 485mm (Framed approx. 1160 x 810mm)
Photograph: Printed on Hahnemuhle Fine Art Photo Gloss 'Baryta' 325gsm paper, using giclee printing and HP Vivera inks guaranteeing an acid-free, fade resistant product with a lifespan of 200-300 years.
Printer: HP large format Z3200 photographic printer.
Mount and backing paper: Archival conservation quality 100% cotton.
Frame: Heavy black wooden frame, hand-crafted by Fine Arts Trade Guild registered framers.
Glass: Conservation UV glass, which deflects sunlight and absorbs damaging UV rays for full protection.
Framed: £1645.00 - Unframed: £1475.00


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customer service - Discount code terms and conditions
Discount codes valid only at the time of booking. They are not applicable if flights are subsequently changed.
Discount is an addition to the normal internet discount of £15 per passenger per return flight.
Discount codes are only valid for scheduled flights.
Discount not applicable to infant passengers.
To redeem a discount code, enter it on the payment page when you make booking.
Discount codes cannot be used against airport taxes, charges or fees.
Where the flight base fare is less than the value of the discount, we will only be able to discount by the value of the fare, thereby giving the customer less than the advertised discount.
We reserve the right to withdraw a discount code without prior notice.