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Dispatch in 24 - 48 Hours. Whatsapp +91-9811535600 for any Queries. CASH on DELIVERY
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Saffron for Pregnant brings Best Quality 100% Pure Kashmir Saffron during Pregnancy Purpose Online
Saffron Milk for Fair Baby during Pregnancy
Pregnancy is a time when you receive advice from every mother about your diet, with one general suggestion being to take saffron (kesar) in your food. The world's costliest spice is the most sought after product by pregnant women who want to give all the best things on earth to the baby in their womb.
Before you begin taking kesar during pregnancy, consult your doctor. Saffron cannot be safe just because it is a herb. Even herbs can have adverse effects on you and your baby.
Once your OB/GYN gives you the go-ahead, saffron can prove to be a fantastic remedy for you during your pregnancy. Just like everything else in life, moderation is the key to enjoy the benefits of Saffron during Pregnancy.
Saffron acts as an anti-depressant and helps elevate your mood .When you are happy, you will glow and look beautiful. So the next time you look in the mirror and get upset about your ballooning belly, just have some saffron-based snack to feel happy and good about yourself.
It is Scientifically Proven that saffron helps reduce blood pressure. So if you are pregnant, this unique property of saffron is something that you want to use to your advantage. Potassium and crocetin present in saffron helps you lower your blood pressure .
While the thought of expanding your family is a beautiful feeling, morning sickness can take away this joy. You can combat nausea and dizziness with saffron.
Bloating, gas and constipation go hand-in-hand with pregnancy. The growing fetus exerting pressure on your digestive tract and the hormonal surges are responsible for this. Saffron could be your best friend during pregnancy if you want to take pleasure from optimal digestion. It boosts blood flow to your digestive system and enhances your metabolism. This, in turn, aids in better digestion
Pregnant women are usually anemic. That is why when you get pregnant, your OB/GYN tells you to consume food rich in iron. Foods Like Pomegranate , Jaggery etc. Saffron is replete with iron and can help boost your hemoglobin levels. It is best to consume saffron in food to ensure optimal results.
Saffron for pregnant is initiative by IKS Saffron for Pregnant to help pregnant women across globe understand the merits / demerits of kesar during pregnancy .
Saffron in some parts of the world is also known by the name of Zafran and better known by the name of Kesar in India. Other than culinary benefits of the wonder spice , it is many medical benefits that have been suggested by medical science as well. One of its several benefits includes the intake of kesar by women during pregnancy. This practise is very popular in Asian countries like India where women prefer to consume kesar milk.
IKS has been the leading marketer of saffron and by products in all regions of India especially the capital city of New Delhi. People in India have a belief that consuming Kesar milk by the women will lead to babies with fair complexion. It is because of the same property of saffron, there have been many cosmetic products claiming to have saffron in them so that people can have fairer complexion.
It has been more than a decade since Indian Kashmir Saffron has been providing its clients with best quality saffron of different varieties. Other than cosmetic purposes, It is also used in adding a unique aroma to food ranging from lassi, kheer and Biryani. Elderly people in India advice women to drink a glass of saffron milk every day during pregnancy so that they can give birth to a baby with fair complexion. However, certain medical experts claim that there is no proof for such benefit of Kesar as the complexion of the baby depends a lot on genes or genetics.
Other than the above mentioned propertied, saffron in milk also keeps the body temperature in control and keeps a check on the body pain level of pregnant ladies. There are many more benefits associated with the wonder spice and the same can be felt if one takes a deep look into the ancient history of medical studies. The quality of service offered by IKS can be seen through the long list of satisfied clients that have been associated with us for a long period of time. IKS ensures that clients get what they pay for thereby saving them from malpractices like saffron adulteration that is widespread in different parts of the world.
Kashmir Saffron Price per Gram is 850 INR @ IKS – Saffron for Pregnant – ( www.saffronforpregnant.com)
Is it safe to drink saffron (kesar) milk during pregnancy and will it influence my baby's complexion?
Yes, Absolutely, it is 100 Percent safe to consume Saffron (alternatively known as Kesar or Zaffran ) with milk . But assumingly it is another spice / herb so the quantity should always be monitored. We at Saffron for Pregnant team highly advice to consult your doctor or Gynecologist before you start consuming saffron. We are 100 % Sure about our product Quality but in Regards to Quantity we highly recommend to consult your Doctor.
Due to healing powers of this golden spice, Saffron is used over decades for Healing purposes. It is very popularly used to relax stressed muscles. It is also used very commonly to relieve stomach aches. Saffron is used during pregnancy to improve digestion & help expecting women's to increase their appetite. & In regards to Baby Complexion , it is more of combination of Genes Effect but since ages our elderly people have been advising pregnant women to consume saffron for fair child.
When can I start Taking Saffron during Pregnancy?
As such there is no Best time to start consuming saffron during pregnancy, However We at Saffron for pregnant Team Highly Recommend to start it as soon as possible. Usually it is recommended to be taken with Milk since Milk is good source of Proteins & Calcium. Just add 3-4 Strands of Pure Kashmir Saffron to a glass of milk and add sugar as per taste, Add some cardamom & Dry Fruits to enhance the taste and Enjoy Milk in Morning and at Night hours. Alternatively you can add few saffron strands to kheer , lassi , Biryani and many other recipes.
What should I keep in Mind before buying Saffron?
Considering Saffron is Highly Expensive product so it is found many times being adulterated by some odd elements. Buy Saffron from Branded Portals only. Do not Buy Saffron in loose without proper packing . Do check for Crop Year on the pack of saffron while buying such spice online. We at India Kashmir Saffron supply the saffron which is procured from Recent Crop year of Dec 2016. Our is Spice board of India Registered Company and also the Saffron we sell is lab tested before Dispatching.
How should I Store Saffron purchased from Saffron for Pregnant?
We at Saffron for pregnant understand it is very important to store the expensive spice in right manner to maintain the aroma and Quality of the Product. We usually Dispatch the Product in 1 Gram Packs. Which mean if you ordered 10 Grams Saffron, we will be sending 10 Packs * 1 Gram = 10 Grams. So we usually recommend you to open 1 Pack at a time and store remaining packs in cool dry dark place.
List of States & Union Territories in India where IKS – Saffron for Pregnant deliver Pure Kashmir Saffron?
Note:- We deliver to each and every PIN Code in India, So place your order for IKS Saffron without any delivery hassle.
States:- Andhra Pradesh (Hyderabad), Arunachal Pradesh (Guwahati), Assam (Dispur), Bihar (Patna), Chhattisgarh (Bilaspur), Goa (Panjim), Gujarat (Gandhinagar), Haryana (Chandigarh), Himachal Pradesh (Shimla), Jammu & Kashmir (Srinagar), Jharkhand (Ranchi), Karnataka (Bangalore / Bengaluru), Kerala (Thiruvananthapuram), Madhya Pradesh (Bhopal), Maharashtra (Mumbai), Manipur (Imphal), Meghalaya, Mizoram (Aizawl), Nagaland (Kohima), Odisha (Bhubaneswar) (Orissa), Punjab (Chandigarh), Rajasthan (Jaipur), Sikkim (Gangtok), Tamil Nadu (Chennai), Telangana (Hyderabad), Tripura (Agartala), Uttar Pradesh (Allahabad), Uttarakhand (Nainital), West Bengal (Calcutta / Kolkata).
Union Territories:- Andaman and Nicobar Islands, Chandigarh, Dadra and Nagar Haveli, Daman and Diu, Lakshadweep, Delhi – National Capital Territory, Puducherry (Pondicherry).
Can you deliver IKS Kashmir Saffron to my Country?
Yes we can deliver it to following countries Worldwide:-A – Afganistan, Argentina, Australia, Austria.
Is Saffron Effective for Fair Complexion of baby ?
Yes , Pure Saffron is Believed to give fair complexion to baby as told to us by Ayurvedic generation , However Scientifically a lot credit goes to person genes and various combination of factors aswell. How ever consuming Saffron Milk is a good choice during pregnancy because of numerous benefits attached to it for mother and baby health.
When will my Saffron Expire?
Usually the Shelf Life of Product is 3 years starting from crop year.
Should you require any further Help just Drop us e mail – firstname.lastname@example.com
Or What's app – 09811535600


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Scent Sends Bees Down Memory Lane
January 29, 2004
Honeybees can be induced to return to a food source simply by being reminded of its smell, researchers report in a Brief Communication in the January 29, 2004 Nature. A particular scent can prompt bees to leave the nest and journey to a previously visited site associated with the same scent - even though food may no longer be present when they get there.
Bees use odour as well as visual cues to find their way to food sources that are often several kilometres away. If the scent of a previously visited source is blown into the hive, bees take off towards the site where they learned the smell, report Judith Reinhard and colleagues.
This process probably works independently of the 'waggle dance' used by bees to describe food locations to their nestmates, the authors add. Bees who arrive home smelling of a particular nectar may jog other bees' memory of the scent, spurring them to make a similar trip.
Abstract © 2004 Nature
"Scent-triggered navigation in honeybees," Judith Reinhard, Mandyam V. Srinivasan, Shaowu Zhang, Nature, January 29, 2004
Judith Reinhard, The Australian National University, Canberra

subset: commoncrawl


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Article Preview
THE DANCE: AMERICAN BALLET IN DEBUT; A New Group Emerges From Training for First Public Tour -- Local Performances of the Week
By JOHN MARTIN. ();
November 04, 1934,
, Section DRAMA-SCREEN-MUSIC FASHION-ART-RADIO, Page X8, Column , words
THE American Ballet of New York, which was established here a little over a year ago with Georges Balanchine as artistic director and choreographer, plans to emerge from its training period and make its first public appearances next month.
November 04, 1934
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Or, purchase this article individually for $3.95 and download a high-resolution PDF.
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text:
Revisited is a fashion and home goods label created by fashion designer Adriana Sanz and industrial designer Joris Debo in Brooklyn, New York, in 2010.
Together they curate, revisit, create collections of minimal, effortless, unique pieces.
Currently they split their time between Antwerp, New York and Barcelona.
For sales related matters please email us at email@example.com.
And for any other information at email@example.com


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Member since 10/30/2013
- 2 total posts
- 2 questions
Questions from viraj4
How soon after septorhinoplasty can I go back to kissing my girlfriend without worrying about damaging the result?
Worry about damaging septorhinoplasty result?
Hi. I am just over a year post-septorhinoplasty. I still worry about causing harm to the result. A few times I've woken up face down with my head buried into the pillow - will... READ MORE


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By Vincent Gono in Masvingo
A Zimbabwean man was stunned to silence after he came face to face with a naked old woman - vampirically sucking his daughter's breast in the middle of the night, The Zim Diaspora can exclusively reveal.
The shocking incident has left people in headman Masunda's area, Chivi district, Masvingo dumbfounded and horrified.
Although the case was not reported to the police, headman Chinodya Jongore Masunda confirmed the incident and said he presided over the matter at his community court last week.
Headman Masunda told our correspondent during a visit to the district last week that the man claimed to have come face to face with the witch who then quickly vanished into the thickness of the night.
The man, headman Masunda said, claims that his daughters were always complaining of breast pain and he decided to visit a prophet who gave him some holy water that he sprinkled in the house before they retired to bed.
The holy water was meant to give him power to see the witch when she came into the house.
They then went to sleep and at midnight the man claims to have seen the woman stark naked going into his children's bedroom and he followed her.
He claims to have seen the woman kneeling down sucking the breasts of his teenage girl who had allegedly been complaining of breast pain.
The man claimed that he moved closer but the woman felt that something was wrong and she quickly got up and vanished into the dark night leaving the man stunned in horror.
In the morning, headman Masunda said, the man got up early, took his axe and went to the forest where he cut a branch of a tree known in Shona as "chizhuzhu'' that he took to the woman's house and blocked the entrance to her kitchen.
The headman told the our correspondent that the branch of the tree had a cultural significance that meant that the man was convinced that the woman was a witch.
The headman said the man was therefore accusing the woman of witchcraft.
The woman, however, was well aware of the significance of the branch of the tree that had been put by the man and reported the matter to the village head who in turn referred the case further to the headman's court.
Headman Masunda, however, said the man, despite talking with so much conviction, failed to prove his allegations when he was brought to the headman's court and was charged for witchcraft accusation. He said the problem was that the man failed to catch the alleged witch in the act so this presented a problem to the court.
He was initially asked to pay two beasts and 200 rand by headman Masunda's court but leniency was exercised and the fine was reduced to a single beast and 200 rand.
The headman said the man, who believes that he was being punished unjustifiably, had not yet paid anything.
"It is true that there was such a case in my area that I presided over. The man, however, failed to prove his case against the woman and my court convicted him. He was alleging that he had so much faith in the prophet who gave him the holy water and was so convinced that he saw the woman kneeling and sucking the breasts of his teenage girl. Asked why he didn't catch the woman, the man said the woman quickly vanished into the night after feeling his presence,'' said headman Masunda.
The traditional leader decried the increase in the number of prophets in his area saying it had led to an increase in the number of cases involving witchcraft accusations.
Attempts by our correspondent to get a comment from the man were fruitless as he was said to have gone to Mashava.


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I have am EM hard www.emsp.no on my test net with more than 2000 rules, only
if the net bandwith is very hard, we have a little problems. The problem
more detected is
With many connections from the same protocol, specially pop3 , from an IP
and to one IP.
A lot of static routes is a hard work to the m0n0 if the hard is a low
But the maintenance for a high rules number is very hard, for this I prefer
sonicwall 1260 or 2040.
Best regards
Tech Services Terapies.org
Jan Arbona
-----Original Message-----
From: Odette [mailto:odette dot nsaka at libero dot it]
Sent: Tuesday, June 06, 2006 4:15 PM
To: m0n0wall at lists dot m0n0 dot ch
Subject: [m0n0wall] Rules number limit?
Hi all,
I need to substitute our production firewall, and I'd like to use M0n0wall
which I've already successfully used for home or small office environments.
The solution I'm going to substitute is based on Linux-iptables which
requires more than 1000 rules. I need more than 25 static routes, and 5
Furthermore, in the next future we are migrating 2 of 3 network branches on
I'd like to try with m0n0, but my boss (I'm sure) will kill me in the event
I spend half a week in setting up the new m0n0 and writing down all the
rules to see that m0n0wall is not the right solution.
Is there a rules number limit or a session number limit implemented in m0n0?
Does somebody have some expertize in similar situations?
Anybody able to supply info or suggenstions?
Tanks in advance
To unsubscribe, e-mail: m0n0wall dash unsubscribe at lists dot m0n0 dot ch
For additional commands, e-mail: m0n0wall dash help at lists dot m0n0 dot ch


text:
Join as a member. There's a certificate with your name on it.
Download uc_ajax_cart-6.x-2.2.tar.gztar.gz 28.62 KB
MD5: 9e52134d29612c0eb09a651275eb4dde
SHA-1: 9ca9c4969dd21059a3f7cb9d77dfa9ab54f89ec0
SHA-256: 974bec41e2af346b440d94af7d9334777f0350645e3b8fb8529b721b0c8d670b
Download uc_ajax_cart-6.x-2.2.zipzip 33.73 KB
MD5: dfad2a2b6e832c1554f7666789bb930a
SHA-1: 9dd1f5897616474ecdc74e63cdcb462c43e40b39
SHA-256: 4a57ac6f370cbc7d03ed5f965a6f8091d62aa6e08aab58a263ce1c47d0379011
Release info
Created by: stewart.adam
Created on: 6 Jan 2013 at 18:33 UTC
Last updated: 7 Jan 2013 at 06:47 UTC
Core compatibility: 6.x
Release type: Bug fixes
Release notes
This release is a primarily bugfix release. It resolves issues blocking the 6.x-2.2 blocker tag.
Note: Issue 1881758 is currently being investigated, 6.x-2.2 may have broken the cart contents block for anonymous users when caching is enabled.
Issues resolved:
- #1429944: Duplicate message when remove item from cart
- #837176: Less Intrusive Status Update for Customer
- #1493398: Hitting Enter when changing a quantity resubmits the form and can lead to further issues
- #1637656: Use AJAX cart/Add to Cart buttons only when viewing website on mobile device?
- #1664188: Invalid argument in foreach in uc_cart.module on line 1614 on /uc_ajax_cart/update
- #1635010: Call undefined uc_product_get_attributes() method in uc_ajax_cart_add_to_cart()
A patch from hanoii also caused some restructuring in the module to make the popup messages generated by JavaScript more themeable using Drupal.theme(). The refactoring also resolves #1778548: Popup message simply says "cart"... customers assume something is broken.


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Here's how you can install Wine 1.6 in Linux Mint 15.
1. Open a terminal window.
2. Type in the following commands then hit Enter after each.
To install it by PPA, use these commands:
sudo add-apt-repository ppa:ubuntu-wine/ppa
sudo apt-get update
sudo apt-get install wine1.6 winetricks
To install it from sources, use these commands:
sudo apt-get install flex bison qt3-dev-tools qt4-qmake
wget -c http://prdownloads.sourceforge.net/wine/wine-1.6.tar.bz2
tar -xjvf wine-1.6.tar.bz2
cd wine-1.6*
cd tools
The official release announcement has many details about what's in Wine 1.6. Be sure to read it before doing an install of Wine 1.6.
If you run into problems, see the Linux Mint Forum for help. There are a lot of very experienced Linux Mint users there that might be able to assist.
Read more: Linux Geekster
This article is published as part of the IDG Contributor Network. Want to Join?


text:
Inergy Mind Spas
Mental Fitness at Work
Scientific Evidence
Light and Sound technology has been researched for many decades. More and more scientific studies are proving its many benefits. No longer are mind and body technologies getting the cold shoulder by the medical, wellness or preventative health communities.
Rather, the research, like that listed here, is proving that light and sound technology is becoming a mainstream treatment for complete, or genuine whole person treatment.
- Comprehensive Review of the Psychological Effects of Brainwave Entrainment
- Time Flashes: A Short History of Sound and Light Technology
- The Clinical Guide to Sound and Light
- Audio-Visual Entrainment: The Application of Audio-Visual Entrainment for the Treatment of Seasonal Affective Disorder
- A Pilot Investigation of Auditory and Visual Entrainment of Brain Wave Activity in Learning Disabled Boys
- Applying Audio-Visual Entrainment Technology for Attention and Learning
- Audio-Visual Entrainment: History and Physiological Mechanisms
- The Science Behind Holosync® and Other Neurotechnologies
Sample A Session
"For Best Results Listen with Headsets."
Here are 8 samples of our empowering sessions. Have a listen.
You will need the latest version of Flash Player available here.


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|Trad, 100'
|YDS: 5.9 French: 5c Ewbanks: 17 UIAA: VI ZA: 17 British: HVS 5a [details]
|New Route:
|Page Views:
|Submitted By:
|Matthew Fienup on Aug 20, 2008
|Comments on Unknown, South of Tree Route
|Add Comment
|Show which comments —
By Matthew Fienup
From: Ventura, CA
Oct 14, 2009
This is an AWESOME first pitch alternate to Anti-Jello. From the bolted anchor, head straight up into the classic tips crack.
The route is also a useful diversion while waiting in line for the Tree Route.
By Schiffhauer
From: Bakersfield
May 10, 2010
|...Also makes a good first pitch to Tree Route.
By Cunning Linguist
Sep 19, 2011
|Tacky anchor next to a perfect 2"-3" crack, contrived crux that is easily moved past on the right, crispy small edges-not a classic for sure and pales when compared to its 4/5 star neighbors. Other than convenience to get a few more feet of climbing in and a quick rap, I wouldn't reccommend this one.
By Fat Dad
From: Los Angeles, CA
Aug 13, 2013
rating: 5.8 5b 16 VI- 15 HVS 4c
|A better start to Anti-Jello, and fun, but pretty contrived. Apart from a 5.9 move at the very start (which can be made easier by stepping off a large flake to the right), I'd say the climbing is pretty standard 5.8. It can be rapped or TR'ed with a 60 m.
By nathanael
From: Riverside, CA
Jun 15, 2016
|Fun start that makes Anti-Jello a hair more sustained.


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Prime Minister David Cameron has defended the decision to charge VAT on hot food served by shops and supermarkets.
Mr Cameron said that the move - which will add 20% to the cost of hot pies and pasties sold by shops such as Greggs - would defend takeaway restaurants against competition from major chains.
Chancellor George Osborne was accused of being out of touch after he was unable to recall when he last bought a pasty as he answered questions on Tuesday about the so-called "pie tax" in Parliament.
But Mr Cameron was quick to declare himself a keen pasty-eater, telling reporters he recently bought a large one from an outlet at Leeds station, adding: "And very good it was too."
Greggs chief executive Ken McMeikan has said ministers had "lost touch" and did not appreciate the impact the changes to VAT rules would have on ordinary people. The high street chain saw millions wiped off its shares after the Budget closed a loophole that has meant some hot takeaway foods, such as sausage rolls and pasties, escaped the duty.
But speaking at a Downing Street press conference, Mr Cameron said: "Many, many small businesses in this country, whether selling fried chicken or fish and chips or hot takeaway pies, are already paying VAT. What the Government has to try to do is make sure the VAT rules are fairly applied.
"I don't think it is fair that the small businessman running a fried chicken takeaway is having to charge his customers VAT but the big supermarket isn't having to pay VAT on fresh hot chicken. It's about trying to have a sensible VAT arrangement where the boundaries are sensible."
Leeds station's last pasty shop closed earlier this month. The Cornish Bakehouse concession stands empty in the main concourse. Workers said the station once had a branch of the West Cornwall Pasty Co but it shut in 2007.
Labour leader Ed Miliband talked to the press outside a Greggs outlet in Redditch, where he and Ed Balls made a brief stop to buy eight sausage rolls at a cost of £4.70. He said: "There is a serious point here which is that the Government is hitting people's living standards in every way they can."
Mr Cameron did not appear exactly sure of the details of his pasty purchase when he mentioned it during a Downing Street press conference about the Olympics: "I am a pasty-eater myself. I go to Cornwall on holiday, I love a hot pasty. I think the last one I bought was from the West Cornwall Pasty Company. I seem to remember I was in Leeds station at the time and the choice was whether to have one of their small ones or one of their large ones."


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> I can't say how much time it would take to reinstall the user's choice
> of ports, but they have to be reinstalled whether one does a fresh
> install or a PBI upgrade.

In my case I started the 1.5 patch on my 188.8.131.52 system around 0037Q and finished around 0130Q. After that I started installing my ports and completed most of them around 0505Q that night.

The only problems I had during the upgrade was having to re-install my shell before starting a desktop but that is understandible when ones using one from ports.

I was very happy to see though that while it seems that the update did pkg_delete on every thing, it did not just up and delete every thing in /usr/local/. I have Vim 7 compiled from source code and it still works perfectly fine hehe.

TerryP.

--
 [SAS]_Spidey01
 Regimental Sergeant Major
 22nd Special Air service EVR


text:
Emir Kusturica launches new Kustendorf Film Festival in Serbia
Emir Kusturica has announced a new international film festival to be held in his villageDrvengrad at the mountain Mokra Gora in the Southwest of Serbia. The first Kustendorf Film Festival will be held Jan 14-21, organised by Kusturica's production company Rasta Film International and under the auspices of the Ministry of Culture of Serbia.
Restricted Content
Registration is required to read the entire article and to gain access to other restricted areas of the website


text:
Recent Memorial Pages by Tetched1963
1–2 of 2 results
James Nathaniel Keen Memorial Page
by Tetched1963 and others can contribute.
Created 06 Apr 2013
A Kinmundy Williams Clan
A place to tell the store of one family, it's people, places and history so that other interested persons may learn and enjoy.
by Tetched1963 and others can contribute.
Created 14 Jul 2010
What is a Memorial Page
Memorial Pages are a new way to collect and share everything you know about someone or something. Learn more.
Search millions of Memorial Pages and start contributing to that page. Search Memorial Pages »
Create a new page from scratch. You can create a person, place, event, organization, or topic pageCreate a New Page
Popular Titles
Civil War Pensions Index
WWII "Old Man's Draft" Registration Cards
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text:
The Shakespeare Conference: SHK 10.1972 Friday, 12 November 1999.
Date: Thursday, 11 Nov 1999 15:43:48 +0100
Subject: Who is William Shakespeare and how do I start reading him?
Cheers to everybody!
This is a question (or rather a pack of questions) from a German
highschool teacher.
Imagine a friendly, linguistically gifted pupil, aged 15 to 17, a
bookworm maybe, comes up to you and says: "Well, I


text:
Winterlude was designed and knit for the 2010 Winter Knitting Olympics. Worked from the bottom up with increases on each edge this triangluar shape lace shawl incorporates BOTH lace and cables on a ribbed base. As with all my designs the pattern is both charted and written out. The "really cool loopy i-cord" edging I devised for this piece can be worked with, or without, beads.
Pattern is delivered electronically upon purchase in PDF format. You will need Adobe Reader to view/print this pattern.
Please contact a Nelkin Designs stockist if you would like to purchase a hard copy of this pattern.
No duplicating except for personal use. Please do not copy and share with your friends or colleagues; each sale of a pattern helps support my designing. Items knit from this pattern may not be sold except with permission of the designer.


text:
*Midfielder Chris Pontius underwent additional surgery on his left hamstring this week in Santa Monica, Calif., and will miss another four to six months. On that timetable, he might not return this season.
Pontius, an MLS Best XI selection two years ago, had an operation in November and was expected to return in time for the season opener in March. However, he suffered setbacks during preseason and discontinued workouts several weeks ago. Plans for further surgery first emerged last week.
*Goalkeeper Bill Hamid is training regularly after missing three matches with a toe injury. In his absence, Andrew Dykstra has conceded one goal and given steady performances. With Hamid available this Saturday night against FC Dallas at RFK Stadium, does Coach Ben Olsen face a lineup dilemma?
"I wouldn't call it a dilemma," Olsen said. "I would say Dykstra did a great job and I would continue to say I have three very good goalkeepers and that I feel very comfortable relying on any of them this weekend."
*Midfielder Luis Silva, out for three matches with an ankle injury, and defender Chris Korb, sidelined since preseason with a knee ailment, are participating in regular training sessions and under consideration to return to the game-day roster this weekend. Midfielder Chris Rolfe is fine after treating a sore quadriceps upon his exit from Saturday's match. Defender Sean Franklin received several stitches from an elbow to above the eye against the Crew. Forward Michael Seaton is training without issues after departing early in the Richmond Kickers' match Saturday with an ankle injury.
*Olsen's reaction to the referee organization's review of a missed red card at Columbus:
"It wasn't something I was surprised at. It was a no-brainer to me. It's good they do [the reviews]. They have been more transparent with how they interpret the laws. It's positive. But when I read it, it just pisses me off again."
That said, Olsen reiterated his club should have secured three points in Columbus.
"We had plenty of chances to kill that game off. This game shouldn't have come down to the last 10 minutes. We had plenty of chances to make it 2-0. We certainly all understand we should have been up a man for a longer duration. … We're pissed off about the two points we left on the table, and hopefully the lessons we've learned week in and week out will not repeat. It's important they don't show themselves every other week — that was a big issue last year. We went over things and we didn't necessarily learn."
*Olsen, on Eddie Johnson's scoreless rut through six matches:
"I am sure he is frustrated but he also has a smile on his face because we are doing okay. We're on a four-game unbeaten streak. He is genuinely a team guy right now, and he understands that is what this is about – his team having success. I talked to him about, at the end of his career, is he wearing any rings? He is going to score goals. But put a ring on that finger. Hopefully that is his focus right now."
*After Saturday's match in Columbus, Rolfe joined his family for Easter in his hometown of Kettering, Ohio, a Dayton suburb. "The last time I was there for Easter I was finding eggs in the backyard," he said of the gap since last making it home for the holiday. On Monday he loaded up his car with personal belongings, including his bicycle, and drove 475 miles to Washington.
*United academy players called into recent national team camps:
Defender Suli Dainkeh (Reston, Va.; University of Maryland): U.S. under-20s at Dallas Cup
Midfielder Jose Carranza (Woodbridge, Va.; Prince William Soccer): U.S. under-15s in Italy
Midfielder Ronald Ventura (Kensington, Md.; Potomac Soccer): El Salvador under-20s
Midfielder Jorge Calix (Alexandria, Va.; Team America): Honduras under-20s
Alexis Cerritos, son of former MLS and Salvadoran international Ronald Cerritos, scored in DCU U-14 squad's 3-0 victory over Virginia Rush.
*United's open training session at Cardozo High School in Washington, postponed because of weather early this month, has been rescheduled for next Monday at 3:30 p.m. Admission is free. [Details]
*Fresh off its first victory, the Washington Spirit embarked on a two-match road trip this week, visiting the Seattle Reign tonight (10 p.m. ET) and the Chicago Red Stars on Saturday (8 p.m.). The NWSL live streams all matches on YouTube.


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Vital Statistics at Time of Disappearance
Details of Disappearance
Shu was last seen at approximately 8:00 a.m. in the vicinity of the 2400 block of Sacramento St. in San Francisco, CA. Shu is believed to have traveled to Tokyo, Japan on January 8, 2005. Shu may be in the China, Japan, or Great Britain area.
Investigating Agency
If you have any information concerning this case, please contact:
San Francisco Police Department
(415) 558-5551
Source Information
National Center for Missing Adults


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Each spring, a profusion of pink and white blossom scent fills the air. The reserve offers a short self-guided nature trail with emphasis on other plants of the north coast area.
Seasons/Climate/Recommended Clothing
Coastal/temperate. Summer 50-60. Morning and evening fog is common. Winter 40-50 with 35" of annual rainfall occurring mostly November - May.
Hiking Trails
Nature Trails
Picnic Areas
Directions: 5 miles north of Arcata, take the McKinleyville exit (Central Ave) off of Hwy 101. Drive 2 miles east on North Bank Road and turn left into the reserve.(Latitude/Longitude: 40.9186 / -124.0772)
Azalea State Reserve
5 miles north of Arcata
Humboldt , CA


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Washington » Interior Secretary Ken Salazar told a Senate committee Wednesday that there is no "hidden federal agenda" to unilaterally designate national monuments in Utah and around the West.
Salazar, testifying before the Senate Energy and Natural Resources Committee, downplayed a leaked Interior memo highlighting 14 potential new monuments (including two in Utah), saying it was simply an effort to gather ideas from his staff.
"There's no hidden agenda on the part of my department," Salazar said. "As secretary of the department, I'm interested in finding out what my employees are thinking. ... I do think there are a lot of other people out there who have ideas. No one should be too worried that there is a hidden federal agenda because there is not."
Rep. Rob Bishop, R-Utah, released the Interior memo two weeks ago, arguing that he had unearthed what could be plans by the Obama administration to convert public lands in Utah and other states to national monuments -- a move that would block any development or oil and gas drilling in those areas.
Two of the sites listed are in Utah: San Juan County's Cedar Mesa and Emery County's San Rafael Swell.
Bishop's finding set off a flurry of letters and comments by Utah politicians wary of such federal action, remembering how then-President Bill Clinton used the century-old Antiquities Act to name the Grand Staircase-Escalante National Monument in 1996. That move came only days after administration officials denied they were pursuing any action.
Sen. Bob Bennett, R-Utah, rattled off the Clinton administration's behind-the-scenes efforts that set aside tens of thousands of acres of federal lands in Utah and noted that the state had been "burned" before and was suspicious of any talk of more monuments.
"Maybe you felt we overreacted," Bennett said, "but that's because you had not lived through this experience."
Pressed by Bennett, Salazar vowed that no one from the White House was pushing any monument designation.
"Let me assure you, Salazar said, "that there is no direction from the White House on any of this to the Department of the Interior -- zero."
Bennett said he buys that. "I accept at face value your assurance that this is just a discussion."
Salazar was appearing before the Senate energy committee to speak about his department's budget request but fielded his first question of the day from the panel's chairman, Sen. Jeff Bingaman, D-N.M., about the national monument issue.
Salazar said his department's approach on wilderness and protection designations would mirror the committee's recent actions, including Utah's Washington County lands bill, a compromise measure signed into law last year and backed by environmentalists, local leaders and developers.
"That's the kind of approach that we intend to take," Salazar said. "We will listen to the people of this country, state by state."


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Deep in Snow Ebook
by Mike O'Brien & Marthe Bijman
Other versions of this book
Print Book
About the Ebook
Photos of Revelstoke, British Columbia, in winter. We like Revelstoke. It's about 7 hours' drive from Coquitlam, via Highway 1, north from Mission to Kamloops, then east through Salmon Arm and winding passes to the town next to the railway. We like it because it's a real, working town. It doesn't have many aspirations to glamour. Down-town, where the old railway houses, like little wooden jewellery boxes, sit propped up in the snow, the heart of Revelstoke will always beat just as it has done for centuries. And we, the visitors, will pass on through, leaving nothing but ski tracks in the snow.
About the Creator
Marthe Bijman designs books with her own photos as well as the excellent photos taken by Mike O'Brien, a Geologist, on his travels around the world.
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Will the cost the same for Invisalign whether its one arch or both? My dentist told me I need my only lower anterior to have Invisalign but I have notice my upper teeth start to have a bit of a gap. Btw, I am wearing veneers - 9 teeth (upper).
What's the Invisalign Cost for One Arch?
Doctor Answers 2
Invisalign cost for an arch
Invisalign charges the same for one or both arches. I too usually treat both arches to get the very best long term result for my patients. It is very difficult to get a bite right when you treat only one arch. An unstable bite leads to unstable results and a greater chance for relapse or jaw issues.
Invisalign Cost: One Arch vs. Two
Invisalign charges the same amount for one arch as they do for two. I almost always treat two arches together (unless my patient has just finished a porcelain smile design on the uppers). In doing so, I can make sure both get ideal alignment. I also have more control over the bite by treating two. My suggestion - treat both arches since the cost is the same.
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


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Former treasurer Chris Bowen says he will not seek the Labor leadership.
"I have decided I will not be a candidate for the leadership of the Labor party," he told reporters in Canberra on Monday.
Mr Bowen said it was his decision not to run.
"There's an obligation on each of us to make ourselves available for positions of leadership if we feel genuinely that we are the best possible candidate at any particular time," he said.
"Equally, there's an obligation not to put our names forward if we don't feel that.
"The conclusion I've reached will be obvious to you."
Mr Bowen said he would fill any role the new leader wanted him to carry out, including that of shadow treasurer.
Mr Bowen said Labor in opposition needed to be united and focused, to hold the new Abbott government to account and to heed the message from Saturday's federal election.
"We need a period of reflection to determine how best to determine that united and stable opposition but we need to provide it from today," he said.
Labor also needed to build on its "successes and achievements" in government over the past six years.
"We need to acknowledge and build on our strong record of economic growth in difficult circumstances," Mr Bowen said.
"Our ability to introduce landmark reforms like DisabilityCare and better school funding."
Mr Bowen said the deputy Labor leadership was a separate matter.
"We'll see how the leadership pans out," he said.
"Again, there will be a number of very good people interested in the deputy leadership if that should be vacant."
The Kevin Rudd supporter also said the former prime minister could make an "ongoing contribution" to Labor and Australia, although it was up to him to decide what that might be.
"He should be given all the time he needs to make that decision and those announcements and it's entirely a matter for him," Mr Bowen said.
Mr Bowen said Labor had a talented team and noted some names had already been mentioned as possible leadership contenders.
"I think all of those potential candidates are people of great talent and ability," he said.
"They, I know, are going through the process that I have gone through over the last 24 hours to consider their options and they'll make their own plans in their own good time."
Those touted as future Labor leaders include Anthony Albanese, from the Left, and Bill Shorten, from the Right.
If they both decided to stand, the matter would go to the grass roots membership for a vote.
If only one stood, Mr Bowen said that person would automatically be declared the leader.
"If there is only one candidate that doesn't indicate anything other than the fact that there is a consensus emerged, and that is not a bad thing necessarily," Mr Bowen said.
He said his own decision not to stand was made after he reflected on the qualities he thought he could bring to the job, the qualities of other possible candidates and the point in the electoral cycle.
He also considered what he might be able to contribute as shadow treasurer.
"I decided the best fit for me was that role going forward," he said.
Mr Bowen declined to endorse another Labor MP for leader, saying he'd wait to see who nominated.


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Cutting spending in Congress is so difficult because every area of the budget is defended by an army of special interests and perverse alliances that often defy reason and common sense. Nowhere is this more evident than with the federal government's ludicrous $6 billion subsidy of ethanol, which I and Sen. Ben Cardin, D-MD, have proposed to eliminate.
A recent post in The Examiner illustrated why the ethanol subsidy endures despite widespread opposition from the Left and the Right. On one hand, your writer declares, "government support for ethanol is among the most destructive and wasteful giveaways to special interests today."
Yet, on the other hand, he says doing away with the subsidy is a "tax-hike" that would leave money in appropriators' pockets, at which point many Republicans run for the hills.
This analysis is inaccurate and destructive on several levels.
First, the ethanol subsidy is a spending program, not a tax relief measure. If it were solely in the discretionary budget and controlled by the appropriators it would be unmasked as a rank cash payment. Instead, Congress has shifted the spending program to the tax code to protect it from being cut.
Two, this cash payment is nothing more than corporate welfare not-so-cleverly disguised as a tax break that, in the real world, has the impact of a tax increase.
As Pete Sepp with the National Taxpayers Union says, "the refundable VEETC is a prime example of tax policy at its worst. Congress needs to focus on simplifying the tax law and cutting rates for everyone, rather than manipulating the tax law and distorting our economy."
Another damning assessment comes from Matt Kibbe, president of Freedomworks: "[P]olicymakers in Washington have opted for a fuel that can only exist in a world of subsidies and distortions. The energy sector is a prime example of Washington's inability to second guess the marketplace; it is a confusing world of myriad and simultaneous subsidies, taxes, spending programs, monopolies, trade barriers and regulations. Current ethanol policy is bad for the economy and for the environment, and seems driven more by corporate interests rather than any concern for the nation's energy supply."
Ethanol distorts and manipulates the economy by increasing the price of food and energy. While I'm pleased groups like Americans for Tax Reform, who previously opposed the elimination of the subsidy are now neutral, their neutrality is supporting a de facto tax increase on every American consumer.
For instance, the Congressional Budget Office has said the "cost to taxpayers of displacing a gallon of gasoline with a quantity of ethanol that provides the same amount of energy as a gallon of gasoline is $1.78." How's that for efficiency?
Regarding food prices, CBO said, "The increased use of ethanol accounted for about 10 percent to 15 percent of the rise in food prices between April 2007 and April 2008. In turn, that increase will boost federal spending for the Supplemental Nutrition Assistance Program (SNAP, formerly known as the Food Stamp program) and child nutrition programs by an estimated $600 million to $900 million in FY 2009."
The subsidy also exacerbates hunger internationally, which we pay for with increased food aid and defense spending -- both of which are financed with taxes and borrowing.
Emira Woods with Africa Action calls it a "shameless subsidy." She writes, "In the midst of a global food crisis and rising hunger, the ethanol industry expropriates land in Africa and elsewhere to grow food that fuels cars."
Finally, the ethanol subsidy is a tax on anyone who owns a car. In short, the subsidy makes it more expensive to drive to the grocery store to buy more expensive food. Ethanol is a third less efficient than gasoline -- it burns at 68 percent of the energy content of regular fuel. And, by EPA's own admission, ethanol reduces fuel economy, ultimately leading to the burning of more fuel to travel the same distance.
If that isn't bad enough, the ethanol subsidy may damage your engine. AAA, the nation's biggest motoring organization, has said higher ethanol blends may damage exhaust systems, engines and fuel pumps, and destroy catalytic converters.
In a perfect world, the hundreds of earmarks and programs I have targeted for elimination in my years in Congress would be immediately rolled into lower tax rates for American citizens. The next best option is to simply cut stupid spending in whatever form it exists. Using the tax code to pick winners and losers in the market should be anathema to conservatives. Eliminating this shameless expenditure should be a no-brainer, especially on this side of the Iowa caucuses.
Source: http://coburn.senate.gov/public/index.cfm/editorialsopinions?ContentRecord_id=e4401167-640c-4519-a358-497376b7c1bf&ContentType_id=efd17605-54a8-44be-90b1-f3794c91987a&Group_id=44ab2b65-c608-40a2-851b-3b51f4e315c9


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Live show January 31, 2016 benefiting "A Promise For Haiti" which supports nurses being sent to Haiti to care for those in need. This was a multimedia show, with several of Claudia's songs visually supported. The "Gunsmoke" footage seen here was created by Kitnkaboodle. She has an entire youtube page dedicated to Amanda Blake!
Filmed November 23rd, 2016 at the Folk Alliance Regional Midwest conference. This song was inspired by one of Claudia's best girlfriends. An appaloosa named Misty Starlight.
"His Left Side"
The cover picture is of Claudiia and her father riding in the Elk Grove Western Festival parade. Claudia on Misty, Dad on a horse called "Dan" by Claudia's sister, but called "son" by her father. No wonder the horse got confused about where he was going! This is probably Claudia's most requested song. Have a tissue handy.
"La Petite Mort"
Live at the Vail Theatre of the Arts in Tucson, AZ on November 16, 2015
Filmed during the "Funny Females of Folk" show featuring Cheryl Wheeler, Christine Lavin, and Cosy Sheridan, the show broke the theater's attendance record!
"Big Country"
With vintage images from Ellis Island and spectacular scenery of American Landmarks, this song tells the story of immigration in America. "Katrina & Ole" in the second verse are actually Claudia's great grandparents Ole & Ingeborg. The blizzard footage was shot 90 miles from where her mother was born and raised in Grenora, ND.
"I Wonder If I'll Miss You When You're Dead"
Filmed during a showcase at the Western Arts Alliance Conference in Los Angeles, CA in August 2013 Watch this video all the way to the end!
Claudia won the Kerrville Folk Festival songwriting competition with this song and another entitled "Georgia Boy". This video is from a live performance at the Folk Alliance Region Midwest Conference in Chicago on October 9th, 2010.
Live performance at Concerts on the Cumberland. It includes footage of actual coyotes in the wild, and captures their howling. The howling was difficult to find because they don't really howl as much as they scream like a dog hit by a car!


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Team Blake Loses Two as Top 12 is Revealed on 'The Voice' [VIDEO]
It's down to the top 12 on NBC's 'The Voice.' America saved Austin Jenckes and Cole Vosbury, leaving the fate of Shelbie Z, Ray Boudreaux and Nic Hawk in the hands of coach Blake Shelton.
Blake struggled with his decision on who to keep saying, 'I hate this part. All three of you are some of the greatest singers, or else you wouldn't be here at this point. I'm proud of all of you. The only thing I can really do is make a call based on my gut. The person I think I can affect change with the most is Ray.' Shelbie Z and Nic Hawk were eliminated.
@NBCTheVoice #VoiceResults my mind is blown right now. 'Merica!!!!!!
— Austin Jenckes (@AustinJenckes) November 8, 2013
We're backstage at the #VoiceTop12Party with @AustinJenckes pic.twitter.com/8DAIKUwsEM
— The Voice (@NBCTheVoice) November 8, 2013
Wow! Still in shock. Thank you so much to everyone who voted me through! Love y'all! #VoiceResults #TeamBlake @NBCTheVoice
— Cole Vosbury (@ColeVosbury) November 8, 2013
"@NBCTheVoice: We're backstage at the #VoiceTop12Party with @katrowbeeshow @ColeVosbury pic.twitter.com/tmq0fpvHXq" Some 1 hug Jonny for me.
— nun ya (@ladyotl) November 8, 2013
We're backstage at the #VoiceTop12Party with @RayBoudreaux pic.twitter.com/nAnymgpTlO
— The Voice (@NBCTheVoice) November 8, 2013
Team Blake Eliminations
Before the eliminations, #TeamBlake took the stage to perform 'Free Ride.'
Team Blake 'Free Ride'
Team Blake will go against the top 3 artists from the other teams.
Team Adam
James Wolpert, Tessanne Chin – America saved
Will Champlin – Adam saved
Team Xtina
Matthew Schuler, Jacquie Lee – America sasved
Josh Logan – Christina saved
Team Cee Lo
Caroline Pennell, Jonny Gray – America saved
Kat Robichaud – Cee Lo saved
The Top 12 take the stage to perform for America's vote Monday night at 8 on NBC. Who are you rooting for this season? Since I predicted Austin Jenckes this year's winner for Team Blake, I'm pro Austin. Although Tessanne may prove to cause Team Blake problems. That girl can sannnng!


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Ashley Putnam
Count Waldner is determined to save his family fortune through a suitable marriage for his daughter Arabella (Ashley Putnam). But his other daughter, Zdenka (Gianna Rolandi) -- who was raised as a boy to save money -- is in love with Arabella's suitor, Matteo (Keith Lewis). Meanwhile, Arabella falls for mysterious stranger Mandryka (John Bröcheler) in this superb production of Richard Strauss's opera from the Glyndebourne Festival Opera Company.


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Johannesburg: Disgraced Australian cricket legend Shane Warne is set to return to South Africa just after the World Cup final for a series of lucrative speaking engagements.Warne, who was suspended from all cricket for twelve months after failing a drugs test for a banned diuretic, has been signed up to speak at functions in Durban on March 26 and in Johannesburg on March 28."Although Shane has been banned from the game, the dates were fixed before that time and I have no problems with him coming here," Ross Fraser, the head of organising body CorporateSport, told on Friday.Warne left South Africa for home on February 11, the day of Australia's opening World Cup match against Pakistan at the Wanderers, when news of his positive test broke."He will be involved in three functions - the two in Durban and Johannesburg as well as a golf day which has yet to be finalised," added Fraser."Originally, he was going to stay on after the tournament, but of course those plans changed. He will probably now come on the Monday after the final as he has no desire to interfere with the Australian team."Tickets for the two morning functions, entitled the 'What Now Warnie?' breakfasts, cost 342 Rand ($ 42)."I think Shane has been very brave in agreeing to talk about what has happened," said Fraser."He could easily have decided to hide away but there will be a question and answer session where people can ask him about what has gone on."The 33-year-old Warne returned the positive test on January 22, which forced him home from what would have been his last World Cup.After earlier denials that he had taken more than one diuretic pill, Warne eventually admitted that he had first taken the banned diuretic on December 12 - to get rid of an alcohol-induced double chin.Warne also said that he took a diuretic given to him by his mother to look good for a press conference to announce his retirement from international One-day cricket.He also admitted to being silly for not checking what tablets he was taking, and said he should have listened more to Australian Sports Drug Agency (ASDA) briefings on banned substances.Warne estimated the ban from all cricket could cost him around three million Australian dollars ($ 1.8 million).The Australian star has enjoyed a hugely successful career with 491 Test wickets helping him to be named as one of Wisden's top five cricketers of all time.Copyright AFP 2001
Kapil the Devil in SA as cheerleader number 1
Hadlee, Akram the best quicks Ive faced: Aravinda


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Topic: Radiation-induced Cardiac Disease
Hi, everyone,
http://www.oncologypractice.com/special … 4f3a.html?
God bless.
cholangiocarcinoma.org :: Cholangiocarcinoma Foundation Discussion Board
a resource for patients, friends, caregivers and loved ones.
You are not logged in. Please login or register.
Cholangiocarcinoma Foundation Discussion Board → Radiation Treatments & Options → Radiation-induced Cardiac Disease
Hi, everyone,
http://www.oncologypractice.com/special … 4f3a.html?
God bless.
Good to know, Percy and something patients should mention to their physicians.
Thanks Percy, I have a very strong family history of heart disease. I have been so inactive the last couple of years, I am starting to exercise but its a slow go.
Thanks for that as well Percy. When my dad was going to day care centre each week he got to know this guy really well who couldn't do chemo for his cancer due to heart disease that he had as well.
Thanks again,
The information expressed is not medical advice. The discussion boards are not intended to replace the services of a trained health professional or to be a substitute for the medical advice of physicians or other healthcare providers. Read the full disclaimer.


text: Bad Teacher Red Band Trailer by Alyssa Caverley at February 24, 2011 6:06 am. Comments Cameron Diaz in the new trailer for the R-rated comedy Bad Teacher Share Tweet Email Edit Delete Like Movies? Sign up for our daily newsletter and receive the latest movie news delivered to your inbox for free! Movie: Bad Teacher Genre: Comedy Related Videos: Bad Teacher Videos, Comedy Videos Related Post: Bad Teacher Red Band Trailer Uploaded by: Alyssa Caverley Uploaded: February 24, 2011 Duration: 157 seconds


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4 arrested in grow house bust in Fort Myers
Published: Saturday, March 2, 2013 at 9:27 p.m.
Last Modified: Saturday, March 2, 2013 at 9:27 p.m.
FORT MYERS — Cranking the air conditioner when it's cold outside led Lee County authorities to arrest four men operating a marijuana grow house.
Acting on a complaint, detectives with the sheriff's office narcotics unit went to a Fort Myers home this week. Authorities found water hoses and pipes on the walls in the back of the home and three air conditioners hooked up to the pipes.
After obtaining a search warrant, four men were arrested on Friday on marijuana trafficking charges. A fourth person was also charged with possession of weapons by a convicted felon. Several guns were found throughout the home.
A sheriff's office statement says having the air conditioners turned on in 64-degree weather "was just one of the many telltale signs" that this home was a grow house.
Reader comments posted to this article may be published in our print edition. All rights reserved. This copyrighted material may not be re-published without permission. Links are encouraged.


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Deferasirox for the Treatment of Chronic Iron Overload in Transfusional Hemosiderosis
Deferasirox for the Treatment of Chronic Iron Overload in Transfusional Hemosiderosis
Purpose: This report describes the Food and Drug Administration's review of data and analyses leading to the approval of the oral iron chelator, deferasirox for the treatment of chronic iron overload due to transfusional hemosiderosis.
Experimental Design: The FDA reviewed findings of a controlled, open-label, randomized multicenter phase III study of deferasirox vs deferoxamine in 586 patients with beta-thalessemia and transfusional hemosiderosis. The study results as well as the results of the FDA review of chemistry, preclinical pharmacology, and supportive studies are described.
Results: Following 48 weeks of treatment in the phase III study, patients' liver iron concentrations (a key endpoint variable) had decreased an average of 2.4 mg of iron (Fe)/g dry weight (dw) and 2.9 mg Fe/g dw in the deferasirox and deferoxamine groups, respectively, despite continued blood transfusions in both cohorts. Deferasirox was associated with serum creatinine increases in approximately a third of patients. Common adverse events included gastrointestinal symptoms and skin rash. Other data provided supportive evidence of deferasirox safety and efficacy.
Conclusions: The FDA granted deferasirox accelerated approval on November 2, 2005, for use in treating chronic iron overload due to transfusional hemosiderosis in patients ≥ 2 years of age. The sponsor must obtain clinical data demonstrating the drug's long-term safety and effectiveness.
Red blood cell transfusion therapy administered on a long-term, recurrent basis is a mainstay in the treatment of several chronic congenital and acquired anemias.[1-3] However, patients receiving such transfusions may consequently develop transfusional hemosiderosis, a major complication of iron overload that sometimes results in heart failure, cirrhosis, diabetes mellitus, or other endocrinopathies.[4-6]
Lessening the body's iron burden through chelation therapy with the parenteral agent deferoxamine has been shown to prevent or delay the complications of transfusional hemosiderosis.[1,2] However, the pharmacologic features of deferoxamine require its prolonged infusion, usually for 8 to 12 hours at least 5 days a week. This inconvenience and infectious complications associated with the route of administration limit compliance with the deferoxamine regimen, and patients may consequently develop progressive manifestations of transfusional hemosiderosis.[7,8]
Deferasirox (Exjade) was developed for use as an orally administered therapeutic iron chelation agent.[9,10] Its safety and efficacy were demonstrated in 48-week controlled clinical trials (with some patients entering extension studies of up to 3 years duration). This review summarizes the major clinical and supportive data and the regulatory process leading to the US Food and Drug Administration's (FDA's) approval of deferasirox for use in the treatment of chronic iron overload resulting from transfusional hemosiderosis in patients ≥ 2 years of age.[11]
Regulatory Background
Prior to the approval of deferasirox, the only drug approved by the FDA for the treatment of transfusional hemosiderosis was deferoxamine.[12,13] Because deferoxamine must be administered parenterally over 8 to 12 hours, the FDA regarded an oral alternative to deferoxamine as an important, unmet medical need. The original deferasirox investigational drug application was submitted on June 30, 1999, and deferasirox received FDA Fast Track status on February 21, 2003. The Fast Track program facilitates development and expedites review of new drugs for serious or life-threatening conditions not otherwise being addressed. Additionally, because of the relative rarity of transfusional hemosiderosis, the FDA designated deferasirox an Orphan Drug (a product that treats a disease affecting fewer than 200,000 Americans). On November 2, 2005, deferasirox received accelerated approval; this approval category requires the sponsor to demonstrate the drug's long-term safety and efficacy.[11]
Iron Metabolism and Chelation Therapy
The process of iron metabolism in the human body (including the limitations on iron excretion) has been well described.[4,5] In a state of metabolic balance, the human body absorbs 1 to 2 mg of iron daily from the diet and loses a similar amount through cellular sloughing. Iron administration in excess of this amount results in sequestration within the body, where it accumulates in end organs and can result in toxicity and organ damage. Since transfusional therapy may require administration of 2 to 3 units of red blood cells per month (each unit containing 200-250 mg of iron [Fe]), patients may present evidence of transfusional hemosiderosis within a few years of monthly transfusions.[14]
Methods to monitor iron stores in patients undergoing long-term transfusion therapy are limited in utility and meaningfulness. Serum ferritin measurement is convenient but correlates incompletely with the body's iron stores.[4] Measurement of iron concentration in a liver tissue biopsy sample is thought to more accurately reflect total body iron stores. Normally, iron concentration in the liver is < 1.5 mg Fe/g dry weight (dw). In patients with hemosiderosis, liver iron concentration (LIC) usually exceeds 2 mg Fe/g dw and may reach ≥ 55 mg Fe/g dw. A patient's cumulative blood transfusion history has been shown to correlate with LIC.[1,4]
A correlation between LIC and the risk of cirrhosis and cardiac damage has not been established.[6,15] However, exploration of the clinical utility of LIC has been especially limited by the invasive nature of liver biopsy. This limitation has prompted the development of noninvasive methods to measure LIC. Assessment techniques such as magnetic resonance imaging and magnetic field detection procedures using a superconducting quantum interference device (SQUID) were partially explored in the deferasirox clinical development program.
Deferasirox is the active component of Exjade tablets for oral suspension. Designated chemically as 4-[3,5-Bis (2-hydroxyphenyl)-1H-1,2,4-triazol-1-yl]-benzoic acid, this agent is a white to slightly yellow powder with a molecular formula of C21H15N3O4 and a molecular weight of 373.4. The structural formula of deferasirox is shown in Figure 1.
The drug product is a tablet in three strengths: 125, 250, and 500 mg. Doses should be calculated so that whole tablets will be used (rounded to the nearest whole tablet). Tablets are not swallowed directly but are dispersed in 3.5 oz of liquid for doses < 1 g or in 7.0 oz of liquid for doses > 1 g. Patients should drink the resulting suspension. The suspension should be used immediately after preparation.
Pharmacology and Toxicology
Deferasirox is a member of the tridentate iron chelator class of drugs. Two molecules of deferasirox bind one ferric atom.
Absorption, Distribution, Metabolism, and Excretion
Deferasirox was rapidly absorbed following single oral doses in mice, rats, dogs, marmosets, monkeys, and humans. The drug and its iron complex were extensively bound (> 98%) to plasma proteins in all species tested, including man. Whole-body autoradiography tissue distribution studies in rats showed the highest levels of radioactivity in the gastrointestinal tract and excretory organs (liver, kidneys, and intestine). Regardless of the route of administration, deferasirox was excreted predominantly via bile/feces in all tested species. Renal excretion of deferasirox and its metabolites was approximately 8% of the administered dose.
The major target organ of deferasirox toxicity in all tested animal species was the kidney; toxicity in other target organs (eye, heart, gastrointestinal tract) varied according to species. Deferasirox was not tumorigenic in rats and transgenic mice.
Human Experience
In humans, peak deferasirox plasma levels were achieved 1 to 4 hours after oral administration. The mean maximum blood concentration (Cmax) and area under the concentration—time curve (AUC) values of deferasirox and its iron complex increased in a dose-related manner within a dose range of 2.5 to 80 mg/kg. Deferasirox steady-state was achieved after 3 days of daily dosing. The drug's terminal half-life ranged from 8 to 16 hours following oral administration. In vitro metabolism studies in human liver microsomes and human hepatocytes have shown deferasirox to be primarily metabolized by glucuronidation, with an acyl-glucuronide being the major metabolite.


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2.0ml, mini version of the Vivi Nova. Takes the same replacement atomizer head as the full size Vivi Nova. This tank based system allows for the atomizer heads to be replaced and the rest of the tank system reused, this reduces overal running costs. The tank holds over 2.0ml and comes with a drip tip. We find the Mini Vivi Nova takes time to break in and reach its optimal usage point.
Please note : Over tightening of the replacement heads in to the cartomizer body/central column may cause a short. Please do not use excess force when screwing in any cartomizers/atomizers.
Please note : The replacement Metal Tanks for the full sized Vivi Nova do not fit the Mini Vivi Nova.
The cartomizers do only have a limited life span. They can last from 2-3 weeks plus depending on usage. They are warranted for DOA only.
Replacement atomizer heads for the Vivi Nova and Vivi Nova Mini.
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EU gives Germany a smack on the wrist over tobacco
The European Commission has sent "reasoned opinions" to Germany and Luxembourg for their failing to convert a European law about advertising and sponsorship of tobacco products into their national law. The two countries have already received formal notices and now have just two months to comply otherwise the EU will take them to the European Court of Justice. The court can impose fines.
"The Commission must ensure that EU law is upheld," said European Health and Consumer Protection Commissioner Markos Kyprianou. "I am determined to enforce this piece of legislation, which is essential in the fight against smoking. I am sure that all governments realise that glamorising smoking through fancy advertising can have devastating effects, in particular on young people. So I strongly urge non-compliant countries to come back into line and help us defend European citizens' health."
The Commission is also investigating countries where things have not been done correctly and says that it will not hesitate to take action if it is proved that the countries involved "have implemented exemptions or granted derogations which go against the provisions of the directive".
The directive bans tobacco advertising in the print media, on radio and over the Internet. It also prohibits tobacco sponsorship of cross-border events or activities. The directive was passed by the European Parliament and Council in 2003 and came into force on July 31 last year.
|Print News Story


text: Case | HBS Case Collection | June 2008 (Revised May 2017) Cook Composites and Polymers Co. Deishin Lee, Michael W. Toffel and Rachel Gordon This case describes how a company improves resource efficiency and process quality in its manufacturing process by developing a waste by-product into a new product. The case describes how CCP cleans production equipment between batches using styrene, which becomes a costly hazardous waste. Having worked on minimizing waste for the past 20 years, CCP believed it could not reduce the use of styrene without risking product quality. Instead, CCP was exploring the development of a by-product from its "rinse styrene," but faces uncertainty regarding the operational, financial, and environmental implications of doing so. This case contains data to support quantitative analyses of financial, operational, and environmental issues including some basic life-cycle analysis (LCA) calculations that focus on greenhouse gas emissions. Keywords: Innovation and Invention; Product Development; Business Processes; Performance Efficiency; Natural Environment; Wastes and Waste Processing; Pollution and Pollutants; Environmental Sustainability; Chemical Industry; Manufacturing Industry; Citation:Lee, Deishin, Michael W. Toffel, and Rachel Gordon. "Cook Composites and Polymers Co." Harvard Business School Case 608-055, June 2008. (Revised May 2017.) View Details CiteView DetailsEducatorsPurchase Related


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Vin Diesel's 'Riddick' Wins Weekend Box Office with $18.7M
The man who can see in the dark is a box office winner.
Riddick, the third installment of The Chronicles of Riddick film franchise, grossed some $18.7 million this weekend, according to The Hollywood Reporter.
Lee Daniels' The Butler and the Spanish-language comedy Instructions Not Included finished in the top three with $8.9 million and $8.1 million, respectively.
Vin Diesel returns as the title character in Riddick, which follows our antihero as he tries to escape mercenaries and alien predators.
The film, which comes nearly a decade after the last installment, 2004's The Chronicles of Riddick, also stars Karl Urban, Katee Sackoff and Matt Nable.
Last week's topper One Direction: This is Us dropped to sixth place, with another $4.1 million in the bank. The 3-D documentary about the hottest group in the universe has grossed nearly $24 million to date.
On deck for next week: Insidious: Chapter 2.
[Lead photo courtesy of Universal Pictures]


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DANNY Lewis believes Harriers can kick-start their promotion chase when they take on Skrill Premier strugglers Lincoln City away tomorrow (3pm ko).
The Aggborough outfit go into weekend ninth in the table, four points off the play-off spots.
But with games in hand over higher-placed Nuneaton, Halifax and Salisbury, Harriers are still very much in the hunt for the Football League.
While the country has been hit hard by heavy rain in recent weeks, Lewis is confident the match at Sincil Bank will not to be in jeopardy.
That's in stark contrast to Harriers, who saw last week's clash against Cambridge called off because of the wet weasther.
He said: "Josh O'Keefe had a spell at City and he said that the drainage and pitch are excellent there and they don't really have games off.
"After losing to Gateshead we wanted to play as soon as we can and put things right but obviously the Cambridge game was called off which was frustrating.
"People may look at the table and see we're four places behind the play-offs but we have games in hand on quite a few of the sides and above us. If we can start stringing a few results together we'll be back in the top five."
With their training ground at Brintons Chainwire too wet to use, the team has been training on Sutton Coldfield Town's 3G pitch and at Wyre Forest Glades Leisure Centre.
Manager Andy Thorn said the squad had a few bumps and bruises to assess and that striker Anthony Malbon had been affected by a virus this week.
Meanwhile, 16th-placed Imps have bolstered their squad by adding former Luton midfielder Arnaud Mendy and Birmingham City keeper Nick Townsend on a youth loan. Winger Mitch Austin has been recalled by Cambridge.
Fans unable to make the clash can follow all the action with The Shuttle's live match updates, followed by a report and reaction.


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Now that the draft has sorted itself out, and the Sixers have an apparent need for a veteran PG, let's take a look around the league and see who's going to be in the market for a PG, and which PGs are available.
- Lakers - Derek Fisher, Jordan Farmar, Shannon Brown (Restricted FA)
- Magic - Jameer Nelson, Anthony Carter (Unrestricted FA), Tyronn Lue (Unrestricted FA)
- Cavaliers - Mo Williams, Delonte West
- Rockets - Aaron Brooks, Kyle Lowry
- Nuggets - Chauncey Billups, Ty Lawson, Anthony Carter (Unrestricted FA)
- Celtics - Rajon Rondo, Eddie House (Player option), Stephon Marbury (Unrestricted FA)
- Hawks - Mike Bibby (Unrestricted FA), Jamal Crawford, Jeff Teague
- Pistons - Rodney Stuckey, Will Bynum
- Heat - Mario Chalmers, Chris Quinn (Player option), Luther Head (Restricted FA)
- Sixers - Andre Miller (Unrestricted FA), Jrue Holiday, Lou Williams
- Mavericks - Jason Kidd (Unrestricted FA), Jose Barea
- Spurs - Tony Parker, Jacque Vaughn, George Hill
- Hornets - Chris Paul, Darren Collison
- Jazz - Deron Williams, Brevin Knight (Unrestricted FA), Ronnie Price (Restricted FA), Eric Maynor
- Trailblazers - Steve Blake, Jerryd Bayless
- Thunder - Russell Westbrook, Earl Watson, Shaun Livingston
- Wizards - Randy Foye, Mike James, Gilbert Arenas, Javaris Crittenton
- Nets - Devin Harris, Keyon Dooling, Rafer Alston
- Knicks - Chris Duhon, Nate Robinson (Restricted FA)
- Bucks - Ramon Sessions (Restricted FA), Brandon Jennings, Luke Ridnour
- Raptors - Jose Calderon, Roko Ukic
- Bobcats - DJ Augustin, Raymond Felton (Restricted FA)
- Bulls - Derrick Rose, Kirk Hinrich, Lindsay Hunter (Unrestricted FA)
- Timberwolves - Ricky Rubio, Jonny Flynn, Sebastian Telfair
- Grizzlies - Mike Conley, Marko Jaric
- Suns - Steve Nash, Leandro Barbosa, Goran Dragic
- Kings - Tyreke Evans, Beno Udrih, Sergio Rodriguez
- Warriors - Monta Ellis, Stephen Curry, CJ Watson (Restricted FA), Acie Law, Speedy Claxton
- Indiana - TJ Ford, Travis Diener (Player option), Jamaal Tinsley, Jarret Jack (Restricted FA)
- Clippers - Baron Davis, Mardy Collins
- Philadelphia
- Portland
- Detroit
- Dallas
- Atlanta
- New York
Now, here's the list of who I consider to be worthwhile free agent point guards. Meaning, guys who could probably handle a starting job, which is what the Sixers are looking for, I assume:
- Jason Kidd
- Mike Bibby
- Andre Miller
- Ramon Sessions
- Jarret Jack
- Raymond Felton
With Brandon Jennings going to Milwaukee with the #10 pick, I'd say it's a good bet that Sessions will not return to Milwaukee.
Charlotte will probably bring Felton back as well. Brown likes having multiple guys who can run the point and I don't see a huge market developing for him.
I'd say the odds are better than 50/50 that Bibby's days are done in Atlanta. Jack is a wild card, no way to tell what Indy is thinking. They may match an offer for him, or he may just play for the qualifying offer and test the waters next year as an unrestricted FA.
For me, the intrigue is going to come from Bibby, Kidd, Sessions and Miller. I assume Portland would like to have any one of them, and they have enough cap space to top the MLE, but I'm not sure they're willing to do it. They may be more likely to try to work a sign and trade, and save the cap space for a wing. Let's assume they do use the cap space for one of them, that would pretty much leave Dallas and Philly as prime destinations for the remaining three, possibly Detroit as well. The rub here seems to be that at least two of these guys are going to have to either re-sign with their current teams, or accept the MLE from one of the other teams in need of a point. There's also the possibility that a contender, like the Cavs, will try to lure someone like Kidd for the MLE to further their "all in" push for a championship with aged veterans.
From the Sixers' perspective, this is how I'd rank the possibilities:
1. Kidd for 2 years, full MLE (possible)
2. Bibby for 2 years, full MLE (doubtful, I think he wants more money, more years)
3. Re-sign Miller for 2 years, $8M per (this should keep them under the luxury tax. I don't go to three years)
4. Sign and trade with Dallas, we send Miller and Dalembert, we get back Kidd (signed to a two-year deal), Dampier, and a future pick.
5. Sign and trade with Portland, we send Miller get back Blake and Outlaw. Not ideal in my mind, but both are expiring contracts so they could be flipped. Blake could be a serviceable point for one season.
There's also another option. We could sink or swim with a PG platoon of Lou and Holiday this season. Maybe add a low-priced veteran like Brevin Knight to the mix and then save the MLE for another piece, like Gortat.
Thoughts in the comments, as usual.
by Brian on Jun 28 2009
Tags: Basketball | Free Agents | Offseason | Sixers |
Tags: Basketball | Free Agents | Offseason | Sixers |


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Beijing • Asian stock markets were mostly lower Monday as investors looked ahead to U.S. corporate earnings following last week's strong job numbers.
Oil declined but stayed above $104 per barrel.
China's benchmark Shanghai Composite Index was off 0.1 percent at 2,059.65 points and Hong Kong's Hang Seng was down 0.1 percent at 23,517.08. Taiwan, Sydney, Seoul and Singapore also registered small declines.
Markets gave up some of last week's gains that followed news the United States generated a stronger-than-expected 288,000 jobs in June, a sign an economic recovery might be gaining traction.
"The market saw another piece of evidence that the U.S. economy is gathering steam while at the same time central bank rhetoric remains dovish," said Credit Agricole CIB in a report.


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PACER Website Redesigned
We recently blogged about changes to the fees for PACER, the federal court system's online records database. Now PACER's website has just been redesigned.
Frequently used links such as registering for a new account are accessible at multiple points on the home page. Answers to frequently asked questions and important news updates are now more prominently displayed. There are also helpful resources for PACER users, such as a guide to case type codes and a user manual.
One new feature announced recently by PACER is the availability of digital audio recordings online. These digital recordings are a fraction of the cost of obtaining a CD at a court clerk's office.
PACER is a subscription service, but you can use it for free at the Federal Clerk's Office of the U.S. District Court for the State of Utah at 350 South Main Street in Salt Lake City.


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Madeleine Potter
The White Countess
Blinded by a traumatic event that took the lives of his wife and daughter, disenchanted ex-U.S. diplomat Todd Jackson (Ralph Fiennes) dreams of owning a gentleman's club. But his life changes forever when he crosses paths with an exiled Russian countess (Natasha Richardson). Acclaimed director James Ivory helms this romantic drama about two lonely people who find hope amid the political turmoil of 1930s Shanghai.


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Governor Malloy of Connecticut recently sent a letter to his fellow Governors asking us to join him in declaring a moment of silence in our respective states on the one-week anniversary of the tragedy in Newtown, Connecticut.
This moment of silence would be accompanied by the ringing of bells by buildings that have the ability to do so, such as schools and houses of worship. The bells would ring 26 times -- once for each life taken at Sandy Hook School, 20 students and 6 educators.
I believe that Governor Malloy chose the number 26 because this particular tribute is focused on the horrible events that unfolded at Sandy Hook School last Friday. The time of 9:30, for example, marks the commencement of the shootings at the school.
We, of course, have honored Governor Malloy's request and followed his lead in shaping this tribute to the victims of the Sandy Hook School shootings. Of course, particular institutions can express their remembrance in the way with which they are most comfortable.
Source: http://www.rigovmedia.com/2012/12/statement-from-governor-lincoln-d-chafee_21.html


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Touran Backpacker Hostel Hostel
No.3 Si Yan Jing, Hupao Road, West Lake District, Hangzhou, China
- HostelBookers
- Hostels
- china hostels
- Hostel hangzhou
- Touran Backpacker Hostel
- Touran Backpacker Hostel Map
Atmosphere 85%
Cleanliness 75%
Facilities 78%
Location 78%
Safety 87%
Staff 90%
Value 88%
- Air conditioning
- Free Wi-Fi
- Lockers
- Self-Catering Facilities
- 24 Hour Reception
- 24 Hour Security
- Adaptors
- Bar
- Bicycle Hire
- Bicycle Parking
- Board Games
- Book Exchange
- Breakfast Not Included
- Cafe
- Common Room
- Free Internet Access
- Free Parking
- Games Room
- Hair Dryers
- Hair Dryers For Hire
- Hot Showers
- Hot Tub
- Housekeeping
- Internet Access
- Key Card Access
- Laundry Facilities
- Linen Included
- Luggage Storage
- Meals available
- Mini Supermarket
- Nightclub
- Outdoor Terrace
- Parking
- Pool Table
- Postal Service
- Reading Light
- Restaurant
- Safe Deposit Box
- Tours/Travel Desk
- Vending Machines
- Washing machine
Important Information
Our Chinese address is ?????????3?
Check-in / Check-out
Earliest check-in: 11:00
Latest Check-out: 13:00
- Age Restriction
- Child Friendly
- Credit Cards Accepted
- No Curfew
- Non Smoking
- Pet Friendly"
- Taxes Included
Group booking?
Group of 15 or more traveling to Hangzhou?
Map and Directions
No.3 Si yan Jing, Hupao Road, West lake District, Hangzhou
(20 meters from the traffic light at the crossroad of Hupao Rd. and Manjuelong Rd.)
The bus stop that's closest to us is "Hangzhou Zoo(????)". If you are coming from
1. Hangzhou Railway Station:
By Taxi: About 30 RMB
By bus Step1 Take subway Line1 to Longxiangqiao Station. 2stops, 4 RMB.
Step 2: Walk through D2 extra and take bus 504 to the Hangzhou Zoo.
After you get off at Hangzhou Zoo bus stop, you just need to walk back for 200 meters on the same road (Which is Hupao Rd
2. Hangzhou Xiaoshan Airport: By Taxi: About 130 RMB (Recommended if you are a group of more than two people)
By Bus:
Step 1: Take the airport shuttle (25RMB/per person) to the Hangzhou Railway Station.
Step 2: Transfer to a taxi, or take subway to the Longxiaongqiao and exit from D2 entrance. And then transter to the bus504 to the Hangzhou Zoo(???) bus stop.
3. Hangzhou South Bus Station:
By Taxi: About 25 RMB
By Bus: Take bus K808 to Hangzhou Zoo.
4. Hangzhou West Bus Station:
By Taxi: Around 35 RMB
By Bus:
Step 1: Take bus K102 to Qing Bo Gate.
Step 2: Transger to K4 and get off at Hangzhou Zoo.
5. Hangzhou North Bus Station: By Taxi: About 50 RMB
By Bus:
Step 1: Take bus K188 to The First Hospital.
Step 2: Walk to Pinghai Road and find the bus station named Longxiang Qiao.
Step 3: Take bus 504 to the Hangzhou Zoo.
6. Hangzhou JiuBao Bus Station:By Taxi: About 80 RMB
By BUS:
Step 1: Take suberway to Long Xiang Qiao 10stops,5RMB.
Step 2: Walk from D2 extra and take bus 504 to the Hangzhou Zoo.
7. Hangzhou East Railway Station
By Taxi: About 80 RMB
By subway:
step 1 :Take subway Line1 to Longxiangqiao Station. 6stops, 4 RMB.
Step 2: Walk through D2 extra and take bus 504 to the Hangzhou Zoo.
After you get off at Hangzhou Zoo bus stop, you just need to walk back for 200 meters on the same road (Which is Hupao Rd
By bus :Take 31 bus to the Hangzhou Zoo.
You will see a 3-floor old Chinese private building on the left after you cross an intersection.


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After two months of not writing for Just a Gwai Lo, I still haven't come up with anything important (urgent!) to write about. Quality control needs improving, and the best idea I could come up with was to hire an editor. Which would mean, in essence, paying someone to tell me what to write about.
(How many blogs are edited in the traditional sense? With assignments, deadlines, correction, feedback, rejection? Has the nature of editing and roles of editors changed because of blogging? Are individual editors relevant anymore that we "crowdsource" the process?)


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What evil lurks behind those innocent-looking cards. . . .
Match the monsters to reveal it!
BlackDog's Halloween Party
Thanks to Eric Harshbarger for BlackDog's Halloween match game applet.
How to Play:
Click on one of the spider cards to turn it over and reveal a
monster. Continue clicking on the cards until you match all the monsters.
When you've matched them all, click on the hidden image to see all of it and to start
the game again.
Careful! Don't let the monsters get you!
Back to the Game


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Love Pets? Here's What to Look for in a HouseRead More
How to identify single family house styles
There are many common house styles found throughout North America. Here's a good infographic that can help you distinguish the differences in some common styles. Source: PartSelect.comRead More
New Year's Resolution – Reducing Your Carbon Footprint
So, it's New Year Day and you may have already started to forget or stray from your resolutions. Instead of being upset with yourself. How about trying a few simple things that will help you reduce your carbon footprint? Here's a few things you can do to reduce your home carbon footprint: Programmable thermostat – […]Read More
City Codes and Guest Houses
Guest House: AKA Granny Unit, Second Dwelling Unit, In-Law Quarters, Accessory Dwelling Unit, Accessory Living Unit, Companion Unit, In-Law Apartment are all ways of describing a second, self-contained unit with its own kitchen located on a property that is zoned for single family residences. If you are looking for extra space for a family member […]Read More
Design is More Than a Floor Plan
A few years ago, a potential client came to me and brought me a floor plan that was completed by a designer. He just wanted me to finish the "plans" so that he could get a permit. In his mind, he had spent months working with this designer to come up with this floor plan […]Read More
What I did during…
Spring and Summer 2016. The end of summer is just about here. The children have gone back to school and we are starting to think about fall and Halloween. Getting together with friends usually means answering the question, "What did you do this summer?" Well, we took one family vacation to New York City, I […]Read More
Approval Process with a Planning Commission or Design Review Committee
If you build a new home or a significant remodel/addition to your existing home anywhere in the San Francisco Bay Area, it is likely that your City, Town or County will require the design to be reviewed and approved by a Planning Commission or Design Review Committee. I recently assisted a client in the Town […]Read More
Step-By-Step Guide To Design, Build A New Home
Q: "I'm planning to purchase a property in Saratoga, CA and build a new house. What is the process from design through construction?" A: When you've chosen a property and have decided to build a new home, first interview several architects. You will want an architect that will help you through the entire process. To […]Read More
Remodeling Your Bathroom – And Complying to CA Codes
If you live in California and you are remodeling your bathroom, you may be surprised to find out that you can't go into any California home improvement, lighting or plumbing fixtures store and buy what they are selling. Many of these stores are owned by companies that are not headquartered in California and they don't […]Read More


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Cancer: The Emperor of All Maladies
Finding the Achilles Heel
Video duration: 1:52:40Video has closed captioning.
This episode starts at a moment of optimism: Scientists believe they have cracked the mystery of the malignant cell, and the first targeted therapies have been developed. But very quickly cancer reveals new layers of complexity and a formidable array of defenses. Many call for a new focus on prevention and early detection as the most promising fronts in the war on cancer.


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The Waltham Forest Guardian has teamed up with the Mall shopping centre in Walthamstow in a competition to make the business dreams of budding retail entrepreneurs a reality.
The Retail Factor contest provides start-up businesses with the chance to trade for free from a Retail Merchandise Unit (RMU) stall at the Mall for two weeks.
There will be multiple spots available and at the end of the period a national winner will be picked from entrants across centres in the Mall chain.
Prizes include the chance to continue trading at a RMU with discounted charges, £500 cash for stock and a place at the Oxford Summer School Academy Course in August 2013.
Entrants are encouraged to submit an application form with their proposals. Applicants will be judged on the strength of the business idea, their consumer understanding, their sales and marketing strategy and their trading strategy.
Alasdair Curry, General Manager of The Mall Walthamstow, said: "We are very excited to be providing local people with a stepping stone to take their business to the next level, particularly given the difficult economic climate, which has made it hard for some great businesses to get off the ground.
"Walthamstow is home to many budding entrepreneurs and we are looking forward to finding and nurturing the next retail rising star."
Tim Jones, editor of The Waltham Forest Guardian added: "The Waltham Forest Guardian is delighted to be supporting this competition, which provides a fantastic local business opportunity.
Due to the current economy we are seeing more and more people starting up on thier own, perhaps doing something they have always dreamed of.
"The Retail Factor will help to kick-start these dreams and turn them into a reality and we look forward to seeing a wide array of entries from our talented community."
The competition is only open to people in Walthamstow.
Visit http://www.themall.co.uk/business/retailfactor.aspx to apply online or pick up a form from the Mall.
The deadline is February 24.


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Saturday's Washington Post is topped by a photo of Barack and Michelle Obama with Pope Benedict, but the image might be misleading, if you think there's an actual story on the Vatican visit in the Post. Instead, the visit is buried in the last two paragraphs in an article praising Obama's personal and racial charisma in Italy. Post reporter Michael Fletcher found great import in the color of the president's skin and his father's history:
White House aides said that during the discussions on hunger this week, Obama personalized the appeal for more aid, pointing out to other world leaders in the room that he still has relatives in Kenya who live in villages mired in poverty.
"You could have heard a pin drop," said a U.S. official who briefed reporters about the meeting.
Obama said after the summit that he had talked about his father's journey from Kenya to the United States in search of better educational opportunities. At that time, he said, the per-capita incomes in Kenya and South Korea were comparable. South Korea has since become highly industrialized and prosperous, he said; Kenya and many other developing nations still struggle.
"The question I asked at the meeting was, 'Why is that?' " Obama said. "The point I was making is: My father traveled to the United States a mere 50 years ago, and yet now I have family members who live in villages -- they themselves are not going hungry -- but live in villages where hunger is real. And so this is something that I understand in very personal terms."
The Post's smoochy account didn't explain how Obama's Aunt Zeituni, an illegal immigrant from Africa, lives in Boston public housing. Isn't that Obama inaction "in very personal terms"? How many of his own book-royalty millions has he pledged to feed his relatives in Africa?
Fletcher's story never answered Obama's question of why Kenya has struggled. It seemed merely designed to showcase Obama's charisma. The headline of the story was "G-8 Countries Pledge Food Aid for the Poor," that G-8 countries pledged to raise $20 billion for food aid for the world's poorest countries. (It's not clear if this is a big headline or press-release blather, since the figure was "up from a $15 billion pledge that Obama secured in the spring during a meeting with world leaders.") Fletcher helpfully cited the White House claims that rising food costs have left "as many as 100 million people at risk of abject poverty."
Obama's Vatican visit was disposed of in paragraphs 19 and 20, in 67 words. They weren't about the Pope's latest encyclical or Obama's liberal stands on abortion and embryo-destroying stem cell research, but about Ted Kennedy:
At the summit's conclusion, Obama went to Vatican City, where he, first lady Michelle Obama and their two daughters had an audience with Pope Benedict XVI.
Afterward, Obama gave the pope a letter from Sen. Edward M. Kennedy (D-Mass.) and asked the pontiff to pray for him, White House national security aide Denis McDonough said. Kennedy, a Catholic, was diagnosed a year ago with terminal brain cancer.


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Is reggae superstar Bob Marley bigger than Jesus? That's debatable, but the music legend who died 28 years ago is about to challenge Elvis Presley and Michael Jackson for the title of richest dead celebrity. A deal with the music superstar's estate is set to generate more than $1 billion in worldwide annual sales by 2012.
Richest dead celebrity: Bob Marley
Current Status: Blessed (1)
Seeded on Fri Nov 20, 2009 9:16 AM
keyboard shortcuts: V vote up article J next comment K previous comment


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Promoting your business with technology products is easy and cost effective with ePromos. Our ever-widening selection includes USB drives, battery chargers, headphones, and Bluetooth speakers. All backed by ePromos' 110 percent guarantee on every purchase. Impress customers with products that they can use every day in their own homes, cars, and on the go to enhance their lives. Place your company logo on the items that your customers will really appreciate by completing a customer order today or call in to work with our brand consultants who love making our clients look great.
This custom cell phone charger will charge your mobile devices with a Micro USB input at the same rate as most wall chargers.
A high quality compact Bluetooth promotional speaker that allows you to share your music anywhere.
This custom electronics case features double pockets and is perfect for carrying audio devices or cell phones.
An aluminum cube-shaped promotional speaker that works with most Bluetooth/wireless enabled devices is perfect to keep in the home or office.
Keep touchscreens clean while reminiscing about your childhood with this building block inspired promotional stylus and screen cleaner.
Always keep an eye on your cell phone with this building block inspired promotional cell phone holder imprinted with your logo.
Filling up all of your USB ports and need more space? This 4-in-1 Custom USB Hub w/ Phone Stand is the solution, with its 4 USB ports!
Never worry about money or electronic devices getting wet with this handy promotional pouch.
Charge on-the-go with this Mini Portable Custom Phone Charger w/ Key Ring! Clients will never be without a charger, simply hook to your keys and you are ready to go.
The Gumbite Spinni promotional cable organizer prevents your cables from tangling by wrapping the cable around the center spindle and closing the outer shell to keep them in place.
Charge two mobile devices at once with this promotional mobile charger that features two USB ports.
This textured faux leather custom tablet sleeve uses magnetic closures that allow folding to create a tablet stand.
Protect your iPad or tablet with this flexible and durable custom iPad sleeve.
Keep your electronics smudge and fingerprint free with this round shaped custom cleaning cloth.
Listen to the radio or music from your mobile device with these Bluetooth custom headphones.
This promotional memory card reader accommodates SD, SD-Ultra, SDHC, MMC, RS-MMC, and HS-MMC memory cards.


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Coffee Shop Retro Gift Set
huge coffee mugs with cool vintage coffee advertising designs, and love the matching canister to keep my coffee super fresh!
This is way too sweet for me, but a cute product none the less. Heart shaped measuring cups and spoons.Tags: home, kitchen, baking, accessories, gifts, home decor, chef, pink, plasticAdded 9 Years Ago from Benblanc
seriously cool bento, the clear part unfolds to become your place mat inside is a lunch container with a cup inside and of course the silverware is included
Set a place for your favorite dinner guests with a decorative and easy to clean up party mat! Match the design to the mood of the meal or just make it fun with a few happy go lucky table covers!Tags: home, kitchen, entertaining, gifts, tables, plates, drinks, snacks, disposableAdded 9 Years Ago from Themacbethcollection