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Create Your First VM In Azure
Jul 25, 2017.
Cloud computing can be a complex term nowadays, as there are already many services that can run on Cloud. Services like Data mining, Machine learning, creating virtual machines, host APIs for mobile applications and many other endless services.
Learn Web API : Using SQL Helper Class
Jul 25, 2017.
This article demonstrates how to use Web API Using SQL Helper Class with easy to use data base access in Visual Studio 2017.
Component In Angular 2 and How to Create Nested Component in Angular 2
Jul 25, 2017.
In this article, we will learn about Angular 2 components and we will also see how to create a nested component.
Creating A Weather Forecast Feature With Microsoft Flow, SharePoint And MSN Weather
Jul 24, 2017.
Today, we are going to create a solution using Microsoft Flow, Microsoft SharePoint and MSN Weather to control the weather forecast feature of my company´s branches in our intranet and I will show you how we can show this information in a simple way to our users.
Creating An Azure SQL Database And Connecting Through SQL Server Management Studio
Jul 23, 2017.
This article demonstrates how to create an azure SQL Database, setting the Firewall rule and connecting through the SQL Server Management Studio.
Pipes In Angular And How To Create Custom Pipes
Jul 23, 2017.
Pipes in Angular 2 and how to create custom Pipe in Angular 2.
Internationalization In ASP.NET Core MVC
Jul 21, 2017.
Globalization is a process of supporting different cultures. Globalization allows us to create multilingual web sites with ASP.net core.
Custom Actions Using CSOM For SharePoint Online - Part Two
Jul 20, 2017.
This is the second post of the Custom Actions Using CSOM for SharePoint Online series. In this post we will see how to create Ribbon Custom actions for different types of lists (Custom List, Document Library and Calendar).
Code First Development Approach With Entity Framework
Jul 20, 2017.
Which one to use in your project is completely your choice and also what you already have in place. Meaning are you designing/developing something from scratch or you already have got DB or domain classes, and also what are your preferences, meaning do you prefer to design classes first and then let your DB gets developed from those classes or you like to design visual class diagram first.
Using PowerShell To Create Log/CSV Files And File Out Commands
Jul 19, 2017.
In many instances while developing using Powershell we need to get the logfile in a specific folder and format.
Learn Angular *ngFor Directive
Jul 19, 2017.
*ngFor is a structural directive and built-in directive that is used to iterate over collections like an array and create a template for each item. To setup Angular2 project in your Visual Studio, Download the "Quick Start Project" from the below given link and use the contents from downloaded folder into your project.
Get User Profile Properties Data in SharePoint Designer 2013 Workflow
Jul 18, 2017.
Workflows helps SharePoint users to collaborate on documents, list items and to manage tasks by implementing business processes on documents and list items. Creating and assigning tasks to Manager is a very common scenario in workflows. All the user related information is stored in User profile service application (UPA). Although this sounds very straightforward, getting the user profile properties of the logged in user is very tricky in SPD 2013 workflow.
Chat Bot with SharePoint authentication - Part One
Jul 18, 2017.
Here we will create a chatbot using LUIS and SharePoint.
Create List With Default Items In SharePoint 2016 Using VS 2015
Jul 18, 2017.
In this article, I would like to share the steps to create SharePoint list with default items using VS 2015. In a previous article we saw how to create document library with predefined folders.
UITableView in Xamarin iOS App
Jul 18, 2017.
In this article, you will learn how to create a list using UITableView in Xamarin iOS, using Xamarin Studio. Xamarin is a platform to develop cross-platform and multi-platform apps (for example, Windows phone, Android, iOS). In Xamarin platform, the code sharing concept is used. In Xamarin Studio, Visual Studio is also available.
BoxView In Xamarin Cross Platform With Example
Jul 17, 2017.
The BoxView is a simple view, useful for drawing solid color rectangles. BoxView is a useful stand-in for images or custom elements when doing initial prototyping. BoxView has a default size request of 40x40. Used creates border property in page.
Creating C# Wrapper Over Firebase API For Basic CRUD
Jul 17, 2017.
Firebase is a platform provided by Google, which provides many services. Firebase Realtime Database is one of them. Firebase provides many SDKs for different platforms as well as it provides REST API to interact with database. Here we will build wrapper in C# around REST api to easily perform CRUD operations in our C# applications.
Create A Microsoft Azure Cognitive Service Face API Application In 30 Minutes
Jul 17, 2017.
In this article, we are going to create Microsoft Azure Cognitive Service Face API in half an hour. Microsoft Azure Cognitive Services are set of APIs and Services available for the developers to make their applications more interactive and intelligent. This was formerly known as Project Oxford. Here Microsoft uses Machine Learning in the background to create these APIs.
Taking Script From Database In SQL Server In Different Mode
Jul 17, 2017.
This article explains how to take the script from database in SQL server in a different mode. Normally we take back up our entire database as ".bak, .mdf, .ldf" file but sometimes we need to alter, update or delete then create our database based on our database modification.
Create SSRS Drilldown Report
Jul 17, 2017.
Create SSRS drill down report, add link enable/disable based on specific condition, adding download links in reports.
Multithreading In C# .Net
Jul 16, 2017.
If you have a program that execute from top to bottom, it will not be responsive and feasible to build complex applications. So .Net Framework offers some classes to create complex applications.
Take Picture With Android Camera Using Xamarin Native Application
Jul 16, 2017.
Reading this article, you will learn how to create camera application in Xamarin application for Android Platform with XAML and Visual C# in cross platform application development.
Python Program To Find All IPs Assigned In A Network
Jul 15, 2017.
This is just a overview how you can create programs to find Network IP. You can do it in more interesting way by using raw_input to assign ip directly from user instead of writing it. Let me know if you need any help or if you are having problem in understanding.
How To Create Simple Game Play Application Using Cross Platform
Jul 15, 2017.
Xamarin is a platform that allows us to create multi-platform mobile applications like (Windows phone, Apple iOS , Android) through a single integrated development environment (IDE). This platform allows the designers to develop and design various mobile platform applications within a limited period. We will discuss how to create game applications using Xamarin.Forms (or) cross platform from VS2017. There are many plugins available including Stack Layout, Label and button.
Uploading File To AWS S3 Using ASP.NET
Jul 14, 2017.
In this article, I will show you how to upload a file (image/video) to Amazon S3 Bucket through a Asp.Net web application. For this first you need to have an account in Amazon web services. You can create an aws free tier account which is valid for 12 months. Visit this link to know more about a free tier account.
How To Create And Deploy Azure Web Apps
Jul 14, 2017.
In this article, we are going to learn how we can create Azure Web App and how to deploy it. Unlike other services, Azure Web Apps service enables us to build and host web applications in the programming language of our choice without managing infrastructure. It offers auto-scaling and high availability, and supports both Windows and Linux.
Best Practices For MVC
Jul 14, 2017.
Add a class library project to the solution, named Store.Model. This library is where we 'll keep all of our domain objects. Entity Framework will count on them in order to build the database but we are not going to configure Code First using DataAnnotations attributes on this project. Instead, we are going to put all the Code First configuration in specific Configuration classes using the Fluent API. Add a folder named Models.
Create A Content Type In SharePoint 2013
Jul 14, 2017.
Here I am going to explain how to create a content type in SharePoint 2013 or SharePoint online and use the same content type in SharePoint list .
Deploying Visual Studio 2017 In Azure Portal
Jul 13, 2017.
In this article, I am going to demonstrate how to create and deploy Visual Studio 2017 in the Microsoft Azure portal.
Creating DLP Policies In Office 365
Jul 13, 2017.
Many organizations and large-scale companies are now making their way to Office 365, leveraging various services offered by Microsoft such as SharePoint, Exchange, Project Online, Microsoft Dynamics etc.
How To Create A List/Library Programmatically In SharePoint 2013
Jul 13, 2017.
We need to install Visual Studio in our machine for creating a list using SharePoint Server Object Model. The Server Object Model will be executed in the server side & it provides a rich set of classes in representing & manipulating SharePoint objects. Server object model is like production server environment to access the data where Sharepoint is installed on the machine.
Create Document Library With Folders In SharePoint Using VS 2015
Jul 12, 2017.
In this article I would like to share the steps for creating the document library with folder in SharePoint using visual studio 2015. In previous articles we saw how to create document library manually in SharePoint online Site.
Creating A Database-Driven MVC Image Gallery With Thumbnails
Jul 12, 2017.
MVC Image Gallery, Save Image in a database, Retrieve Images from a database, Create Image thumbnail from the database, Upload Image through Ajax, Fancy Box Gallery
Promoted Links WebPart In SharePoint
Jul 12, 2017.
In this article, I have explained how to create and use a promoted links webpart in SharePoint.
Creating Internet Connectivity Load Balancer Using Azure Portal
Jul 11, 2017.
Azure provides a variety of networking capabilities that can be used together or separately. But In this Article we will see about the one of the key capabilities (i.e Internet Connectivity).
Creating Our Own TabControl In C#
Jul 11, 2017.
In this article we will create our own TabControl component using Buttons and Panels in very easy steps
Custom Observable In KnockoutJS
Jul 10, 2017.
Knockout JS is famous and widely used for its two-way binding concept. While developing application we uses ko.observable() to declare a knockout object. Here we will discuss how to create our own custom observable which will work same as observable but with our own functionality.
Azure DevTest - Create A Claimable Virtual Machine
Jul 10, 2017.
This article is a continuation of my previous one in which we were dealing with Azure DevTest for creating a Lab environment for testers and developers to host their applications on cloud which will walk with a smart path for them. Click here to surf for it.
Task For Creating Web Part And Assigning It To Document Library Or Lists
Jul 10, 2017.
How to Create Document Library and Assign Web parts to it and assign Another Document Library to these Web parts.
React Tutorials - Day Five - Router
Jul 10, 2017.
Today we learn about the routing in React, we learn how to setup routing configuration and also learn how routes work in React. If we want to create a single page application then we need the routing to redirect from one page to another and read the route parameters. To perform the routing in React we should have to install the "react-router-dom" packages.
Create SharePoint Project And Deployment Steps Using Visual Studio 2015
Jul 07, 2017.
In this article, I would like to share the steps to Create SharePoint project using Visual studio 2015. It is hosted in IIS Worked process i.e. W3WP.exe can affect the whole farm when we run the code. IIS application pool will be recycled when we retract or deploy the farm solutions.
Get Started With Azure DevTest Creating Server Machines With Artifacts
Jul 07, 2017.
Azure DevTest is an effective resource that Azure has come up with for supporting developers and testers to avoid environment delays, allow self-service actions on turning the VM's (Virtual Machines) on or off, and works with simple cost effective solutions to leverage the application which we host on the cloud.
Microsoft Azure Cloud Shell Startup And Creating A Linux VM WebServer Using Cloud Shell
Jul 06, 2017.
Microsoft Azure Cloud Shell is very interactive, easy and browser accessible shell platform for creating, maintaining and managing all Azure resources using portal only. Azure Cloud Shell provides you access to Azure CLI browser based experience which supports built in tasks.
Overview Of Community Site Template In SharePoint
Jul 06, 2017.
In this article, I explained how to create and use community site template in SharePoint online. Community site is a new site template which provides a forum experience in Sharepoint online. Use communities to categorize and cultivate discussions among a broad group of people across organizations in a company.
Deploying A Simple Bot With Bot Builder SDK Using Visual Studio 2017
Jul 05, 2017.
In this article , I am going to show how to create and configure a bot using visual studio and also how to run that bot using Bot Emulator in our local system. This article also shows how to build a bot by using the Bot Application template and the Bot Builder SDK for .NET, and then testing it with the Bot Framework Emulator.
Simulate SharePoint Online Timer Jobs Using Azure Functions
Jul 05, 2017.
SharePoint Server provides native Timer Jobs that inherit SPJobDefinition class to run at regular intervals defined in the SPSchedule object. This way we can create solutions that have to be iteratively run to process logic at regular intervals. However, in case of SharePoint Online Native Timer Jobs cannot be used.
Form Inputs And Sizing In Bootstrap
Jul 04, 2017.
In this article we will about how to create a bootstrap from inputs and sizing, Bootstrap provides several form control styles, layout options, and custom components for creating a wide variety of forms.
Deploying An Azure SQL Database In Microsoft Azure Portal
Jul 03, 2017.
This article shows how to create and configure the firewall and how to run sample sample queries in the SQL Database using Azure Portal.
Microsoft Azure Automation With RunBook Using PowerShell
Jul 03, 2017.
In this article I will show you how to create Microsoft Azure Automation Runbook using PowerShell
Two-Class Boosted Decision Tree
Jul 03, 2017.
Two-Class Boosted Decision Tree module creates a machine learning model that is based on the boosted decision trees algorithm. A boosted decision tree is an ensemble learning method in which the second tree corrects for the errors of the first tree, the third tree corrects for the errors of the first and second trees, and so forth. Predictions are based on the entire ensemble of trees together that make the prediction.
ASP.NET MVC Tooltip Using Web API, Bootstrap Popover And jQuery UI Dialog
Jul 03, 2017.
I am sharing an article on how to create a help tooltip for a HTML element using Web API, Bootstrap Popover and jQuery UI dialog.
Create A Bot With Microsoft Bot Framework Using Node.js
Jul 03, 2017.
In this article, you will learn how to create a Bot using Bot Framework with newly launched Custom Vision service.
Creating TreeView For MVC 5
Jul 03, 2017.
We're going to extend JsTree from JS to MVC and we'll render HTML tags from the database using custom development in the model.
Raycasting In Unity
Jun 30, 2017.
In this article, I am going to explain about Raycasting in Unity. I hope you understand how to create the object and destroy it using C# scripts in unity.
Deploying A Simple QnA Bot Using Bot Services In Microsoft Azure
Jun 30, 2017.
In this demonstration , I am going to show how to create and deploy the QnA bot in Microsoft Azure using Bot Services.
Create Stop Watch Android Application
Jun 30, 2017.
Android is one of the most popular operating systems for mobile. So, I will show you how to create stop watch Android applications using Android studio. Android is the kernel based operating system. It allows the user to modify the GUI components and source code.
FAQs Answering bot using Bot Framework and QnA Maker service
Jun 30, 2017.
In a previous article, I have explained how to educate QnA maker for questions and answers. In this article we will discuss about how to consume QnA maker service in Bot applications created using Microsoft Bot Framework.
Debugging With Chrome In Visual Studio 2017
Jun 30, 2017.
Debugging client side script using IDE is a most exciting feature in Visual Studio 2017, recently I have updated my IDE and after creating a new ASP.Net Core application I have noticed the below splash screen before starting the application, soon later I realize about the new exciting feature and then I decided to explain it to others.
Building Mobile Apps Using Xamarin.Forms With .NET Standard
Jun 30, 2017.
The .NET Standard Library is a formal specification of .NET APIs that is intended to be available on all .NET runtimes. It is a single library with a uniform API for all .NET Platforms including .NET Core. You just create a single .NET Standard Library and use it from any runtime that supports .NET Standard Platform.
ASP.NET MVC CRUD With Dapper (Micro ORM)
Jun 30, 2017.
In this article, you will learn about CRUD (Create, Retrieve, Update, Delete) functionality in ASP.NET MVC with the help of DAPPER, the Micro ORM tool.
How To Create A Grid Dynamically Using Angular
Jun 30, 2017.
Create a grid dynamically with angularjs without hardcoding column names. AngularJS provides various features. One of them is 2 way data binding. In this article I will explain how you can create a grid dynamically from Angular.
Emotion Recognition In Xamarin.Forms With Microsoft Cognitive Services
Jun 29, 2017.
Microsoft Cognitive Services offer awesome APIs and services for developers to create more intelligent applications. You can add interesting features, like people's emotions and video detection, face, speech, and vision recognition and speech and language understanding into your application.
Deploying A Simple LUIS Bot Using Microsoft Azure Bot Services
Jun 28, 2017.
LUIS stands For Language Understanding Intelligent Service which offers a fast and effective way of adding language understanding to applications. With LUIS, you can use pre existing, world class, pre built models from Bing and Cortana whenever they suit your purposes and when you need specialized models, LUIS guides you through the process of quickly building them.It is also part of Microsoft Cognitive Service.
Creating Applications In Ruby On Rails
Jun 28, 2017.
In this article you will learn how to create simple applications in Ruby on Rails.
Cognitive Services APIs In Azure
Jun 28, 2017.
Microsoft Cognitive services provides good number of API and services for vast developers that helps you to create more intelligent applications.
Deploying An IoT Hub Using Microsoft Azure
Jun 27, 2017.
In this article , I am going to create an IoT Hub using Azure.
Deploying A Proactive Bot Using The Microsoft Azure Bot Service
Jun 27, 2017.
This article demonstrates how to create the proactive bot using Microsoft Azure Bot Services.
Working With Variables In Windows PowerShell
Jun 27, 2017.
Windows PowerShell variables are quite different when you compare them with Cmd.exe variables. In Command-prompt, all the variables are environment variables and they can only store a string of text. But in Windows PowerShell, variables can store more than just text, they store objects.These variables help you to create reliable scripts.
Deploying A Form Bot Using Microsoft Azure Bot Service
Jun 26, 2017.
This article shows how to create,deploy and test the Form Bot using Microsoft Azure Bot services.
Creating Custom Routing Constraint In ASP.NET Core MVC
Jun 26, 2017.
In this article, we'll learn how to create a custom routing constraint in ASP.NET Core MVC. Routing constraint is responsible for matching the constraint rules with incoming requests.
Create A Rolling Ball Game With Force And Gravity In C#
Jun 26, 2017.
In this article, I am going to explain about creating a rolling ball game with force and gravity in C#.
How To Create Azure SQL Database And Access It Through Visual Studio Code
Jun 26, 2017.
In this article, I'm going to cover how to create Azure SQL database and how you can access it through Visual Studio code.
Getting Started With Microsoft Azure Cognitive Services APIs Account
Jun 25, 2017.
Microsoft Cognitive Services offer awesome APIs and services for developers to create more intelligent applications. You can add more interesting feature like people emotion and video detection, facial, speech and vision recognition and speech and language understanding into all the applications.
Working With PowerShell Drives
Jun 25, 2017.
Windows PowerShell drives are data store locations that you can access like any other ?le system drives in Windows PowerShell. The Windows PS providers create some drives for you, such as the ?le system drives (including C: and D:). Below examples provides you how to work with PowerShell Drives in Windows PowerShell.
Creating A Function App And Integrating With Azure Logic Apps
Jun 24, 2017.
In this article you will learn how to create A Function App And Integrate With Azure Logic Apps.
Building Apps With Polymer And ASP.NET Core
Jun 23, 2017.
How To Operate With Data Persistence In Xamarin.Forms - Part Two
Jun 23, 2017.
In this one, I'll show you how to use the file system to save data using Xamarin with the .Forms UI Technology and the PCL (Portable Class Library) code sharing strategy.
React Tutorials - Day Three - Components
Jun 23, 2017.
Today, we will learn about components. Component are the heart of React, components let you split the UI into independent and reusable sections. In React to create a component we need to extend the "React.Component" class.
Learn About Bootstrap Tables
Jun 21, 2017.
In this article we will see how to create Bootstrap tables.
How To Create A Sub Site In SharePoint Online
Jun 21, 2017.
In this article you will learn how To Create A Sub Site In SharePoint Online.
Bootstrap - Progress Bars, Alert, Labels
Jun 21, 2017.
In this article we see about how to create a Bootstrap - Progress Bars, Alert, Labels.
Xamarin.Android - List View Using SQL Server Database
Jun 21, 2017.
In this article you will create a Xamarin Android List View using SQL Server.
Bootstrap Pagination And Pager
Jun 21, 2017.
In this article we will see how to create Bootstrap pagination & pager.
Create List Using SharePoint 2013
Jun 21, 2017.
Create List/Library using SharePoint 2013.
Deploying A Virtual Network With Multiple Subnets Using Microsoft Azure
Jun 21, 2017.
This Article shows how to create the Virtual Network and to create multiple subnets
Create Database Project In Visual Studio 2015
Jun 20, 2017.
Create Database Project In Visual Studio 2015.
Creating Azure Data Lake Analytics Using Microsoft Azure Portal
Jun 20, 2017.
This article shows how to create a data-lake analytics using Azure portal.
Creating ASP.NET Web App In Azure
Jun 19, 2017.
Creating ASP.NET Web App In Azure.
Deploying A Simple Bot Using Microsoft Azure Bot Service
Jun 19, 2017.
This article shows how to create a bot using Azure bot services and deploy it.
Accessing Twitter In Azure Active Directory B2C
Jun 19, 2017.
In this article, we will create a Twitter app to access the Twitter account of consumer in Azure Active Directory B2C.
Creating A Multi-Language Store Site With nopCommerce
Jun 18, 2017.
In this tutorial, we will cover topics related to creating a multi-language store site with nopCommerce.
Creating A Nano Scripting Language Using ANTLR And Roslyn
Jun 17, 2017.
A primer into creating a simple scripting language using ANTLR and Roslyn together.
Scripting With C# In Unity
Jun 16, 2017.
In this article, I am going to explain about how to create C# scripts in Unity.
Marking Methods "Obsolete" In C# Class Library
Jun 14, 2017.
In this article, I will explain how a method can be marked as obsolete in C# class library.
How To Create Microsoft Azure Container Service With Mesosphere DC OS Orchestrator
Jun 14, 2017.
How To Create Microsoft Azure Container Service With Mesosphere DC OS Orchestrator.
Creating Bots Using NodeJS Template
Jun 13, 2017.
Bot Creation Using NodeJS Template.
Understanding React Components On SPFx
Jun 13, 2017.
In this article, let us see how React JS components work along with multiple class hierarchy using SharePoint Framework components.
How To Create ChatBot In Xamarin
Jun 13, 2017.
How To Create ChatBot In Xamarin.
How To Create Calendar View In Android Application
Jun 12, 2017.
How To Create Calendar View In Android Application.
Creating VNet Using PowerShell Cmdlets
Jun 12, 2017.
Creating VNet using powershell cmdlets.
About Creating-Class
File APIs for .NET
Aspose are the market leader of .NET APIs for file business formats – natively work with DOCX, XLSX, PPT, PDF, MSG, MPP, images formats and many more!


text:
Ravenna — After a two-week civil trial, a visiting judge will issue a written decision whether two men convicted of a 1988 murder in Hiram Township and who served prison time are innocent of the crime.
Retired Summit County Common Pleas Judge Marvin Shapiro heard two weeks of evidence from plaintiffs Bob Gondor, Randy Resh and their attorneys, plus evidence from assistant county prosecutors.
Prosecutor Victor Vigluicci said he expects the judge's "findings of fact and conclusions of law" to be filed next week.
If the pair gets a finding of "actual innocence" from Shapiro, they can petition the Ohio Court of Claims for financial compensation for wrongful imprisonment.

subset: commoncrawl


text:
Magnify the power of your logo with this customized magnifier and paper weight.
Add a little excitement to your desk with a solar powered logo flower that happily dances and moves all day.
Give your logo plenty of space to shine on this USA made custom rain gauge.
Your company logo will bloom as big as this fun novelty promotional pen.


text:
President Obama wants to end the George W. Bush tax cuts for the wealthy when they expire this year, aides said today.
"He will not support extension of the upper-income Bush tax cuts," said White House press secretary Jay Carney.
"He could not be more clear," Carney added.
The comments came as former president Bill Clinton and others suggest that a temporary extension of all the Bush tax cuts may be necessary so that Congress can work out a long-term deal to reduce the federal debt.
The Bush tax cuts expire at the end of the year, but no action is expected before the Nov. 6 election.
Obama wants to extend the Bush tax cuts only for middle-class taxpayers, and end them for individuals making more than $200,000 a year and couples making more than $250,000 annually. He says the wealthy should contribute more to reduce the federal debt.
Said Carney: "The president's position is that we absolutely should extend the tax cuts for the middle class; we should not extend and he will not extend tax cuts for the highest-income Americans."
The president and congressional Republicans agreed in 2010 to a two-year extension of all the Bush tax rates, the deal that ends this year.
As they did two years ago, Republicans say no one's taxes should be raised in a slow economy.
"It's pretty obvious that the economy needs the certainty of the extension of the current tax rates for at least a year," sad Senate Minority Leader Mitch McConnell, R-Ky. "That would also give us the time to begin to grapple with something we all agree we need to do on a bipartisan basis, which is to reform the whole tax code."
David's journalism career spans three decades, including coverage of five presidential elections, the Oklahoma City bombing, the 2000 Florida presidential recount and the 9/11 terrorist attacks. He has covered the White House for USA TODAY since 2005. His interests include history, politics, books, movies and college football -- not necessarily in that order. More about David
Follow the Oval on Twitter: @The Oval, @djusatoday.
Also contributing to the Oval: Richard Wolf @richardjwolf; Aamer Madhani @AamerISmad


text:
|Thread Tools
We're pretty committed to cloth diapers but when we were away over Christmas we used disposables on my 15-month-old. She often had a very mild diaper rash, but this cleared up completely over the holidays. Now that we're home she's back in cloth, and the diaper rash is back. I was told cloth was better than disposable for diaper rash, so I'm wondering what's going on.
We use AMP with hemp prefolds, often with a flushable liner. We wash with Allen's natural detergent and sometimes vinegar. We often use a butt cream or zinc cream, with the flushable liner so it doesn't get on the diaper.
Any help or advice? We'd really rather not switch to disposables because of the cost and the environment, but I'm not sure I want to be weighing my daughter's health against the environment.
Have you tried maybe using a fleece liner? Or using a pocket dipe that has fleece or suedecloth? This would wick moisture away from the skin and might help with a rash.
The other thing that springs to mind (mostly because we have been dealing with the dreaded yeasties for soooooooome time now ) is a possible yeast rash that could be hanging out in your dipes. You can throw vinegar or GSE in the rinse cycle to kill yeast that's hanging out on a diaper. Might be worth a shot . . . .
Good luck!
L, student nurse and married to A, my union man. Happy parents to little S!
We just went through this too. I think that it helps clear up rash because the disposables wick the moisture away very quickly, and the baby stays drier. My daughter's rash was completely cleared up within 2 days of using disposables. My plan is to leave her in disposables for now and strip her diapers, in hopes that even cleaner diapers than usual will help prevent her from getting further rashes. For the record, my general method of washing included vinegar every time.
One thing you could try is fleece liners, as fleece is supposed to wick away moisture.
bedsharing, knitting, toddler-nursing, nerdy, babywearing mama!
We did the exact same thing over the holidays (disposables are easier when travelling let's face it) and we had the same outcome, diaper rash cleared up. I have no idea why. My DS can only use 1 brand of disposables though (Seventh Generation) as all others give him MAJOR rash within minutes. I too am curious as to what others have to say. We use plain old DSQ prefolds and covers and although his diaper rash is not what I would consider 'bad' it's still there. Every single time we use the SG sposies it clears up. :sigh
mama to one DS and one DD, equally amazing.
Same thing happened to us! However I already use fleece liners and vinegar in every rinse cycle and my DD still had a hint of diaper rash that never ever went away.
She was in sposies for 1 week, no rash and didn't need any diaper cream. FWIW we are using 'green' diapers. I haven't put her back in cloth yet because I was going to strip my dipes.
Sposies are drier, and contrary to what people are always saying, they are more breathable than most cloth diaper covers, which aren't breathable at all. Fleece and wool covers are an exception to that rule, of course, but PUL covers are not breathable. Have you tried not using the vinegar? Also, have you tried not using the disposable liner? Did you keep diaper cream on her when she was in sposies? If not, maybe she's sensitive to the cream itself, although I think that would be relatively uncommon.
Honestly, I think it could be simply that you need to change her more often when she's in cloth, and perhaps try either a wool or fleece cover or some diapers you can use without a cover. Those PUL covers get everything hot and sweaty. Please don't take that to mean I think you're not conscientious about changing your baby. I'm not saying that at all. Some little ones just have SUPER sensitive skin and need to be changed a lot, lot, lot more often than your average baby. So if it were me, I'd get a couple fleece or wool covers and change every time she peed, as soon as she peed. I'd check ALL the time. My guess is that's probably the problem - her skin's just irritated from being hot and sweaty and wet. Obviously, that's just a guess. Whatever it is, good luck getting it worked out. :)
Consider flushable's fault. When I tried them for my son overnight, he had penis inflamation and we had to take him to a doctor. He was 3 m.o. then
I posted something similar on Diaperswappers a week or so ago - we have the same problem. DD has been wearing 'sposies at night because she is a super heavy wetter and was peeing right through her nighttime dipes, and every morning she wakes up dry and rash free. She's in GMD prefolds and Thirsties covers throughout the day and as the day goes on she gets redder and more irritated, but it always clears up magically overnight when she's in the 'sposie
I'm going to Joann fabric on Friday and am picking up some microfleece to make my own liners. I'm also considering ditching the PUL covers in favor of wool or fleece as a PP mentioned - I just ordered a couple from here to try, they are having an awesome sale so you mamas may want to check it out...
We're not giving up CDing without a fight! Although I'm sure DH wouldn't mind
~ Sarah ~ Living the mountain life with DH Dan & DD Lillian 1.6.10 and DS Jack 10.22.11 Trying to find time to !!
Same issue here. Rash (really bad--red spots, like yeast but I don't think it was yeast because I did multiple yeast strips and bleach runs, that eventually became bleeding sores) in cloth, no rash in disposables (like, the rash would be gone within a few hours of putting her in sposies). I almost gave up on cloth because of it. I tried so many things--tons of different wash routines and detergents, multiple strips--I even switched from prefolds and Mother-Ease Airflow covers to fleece pockets (Kawaii) in the hopes that the fleece would keep her dry and get rid of the rash. Nothing helped except disposables and Desitin.
After a few weeks, though, a fairly mild rash started coming back when she was in disposables. That made me go back to cloth since if she had a rash in either, I figured she might as well be in cloth (the environment is my main reason for wanting her in cloth). What we do now is put her in Kawaiis (or sometimes cotton fitteds without covers) during the day and a disposable diaper at night.
I'm still not totally sure what the issue is, though. When I put her back in cloth I cut out a lot of things I'd been doing, sort of a cloth elimination diet, to see if I could pinpoint the issue. The things I stopped using were:
- flushable liners
- coconut oil on her bottom
- any other creams or lotions on her bottom
- cloth wipes (we use disposable Kirkland brand wipes from Costco now)
- laundry additives (I'd tried vinegar, Grapeseed extract, and a few other things at various times)
- an older type of Kawaii diapers that had a funny feeling fleece (maybe it was microsuede or something?) in them
- cloth diapers at night
I've since sloooowly added things back into our routine, one at a time, checking for reactions. So far the flushable liners are back in use without a problem, as are the older Kawaiis. Next up I'll try adding the cloth wipes back in.
I did change our wash routine, too. Previously I'd tried Country Save, Tide, and a homemade detergent made from Borax and washing soda. Now all I use is a big squirt of blue Dawn, and a scoop of Oxyclean. That's it. It seems to work very well. I have a portable apartment top loading washing machine and it has no trouble with the Dawn. I do a full wash cycle on cold with nothing in it but the diapers, and the a heavy duty hot cycle (two wash cycles, one rinse) with the Dawn and Oxyclean. She stays pretty much rash-free now. Once in a while she gets an immediate bad reaction to a poop; if that happens, we put her in a disposable with Desitin and it's gone by the next diaper change.
The frustrating thing (for a perfectionist like me) is that I still don't know what the source of our issues were. Was it the detergents? Was it the cloth wipes, for some reason (the disposable ones seem much softer and gentler to me)? Was it the cloth-friendly diaper creams I used (Baby Bottom Better, coconut oil)? I do think she might be allergic to coconut oil, since it seems like she gets red when I put it on her face. Was it being in cloth all night for 13+ hours at a go, and being in a disposable at night is the golden ticket? Is it that she was teething and so her poop was really acidic for a long time, and she needed the Desitin barrier that we could use when she was in disposables? I'm still not sure.
All that to say that if you really want to stick with cloth, you could try doing what I did:
1) Put her in disposables and slather on the Desitin.
2) Wash all your cloth diapers with a splash of bleach, in hot water. Then wash them a couple of times with a squirt of blue Dawn and a scoop of Oxyclean to remove any possible detergent residue. Rinse several times. Machine dry.
3) Leave her in disposables until her rash completely clears up, plus another week or two after that.
4) Put her back in disposables. Don't use any liners or creams. Use very simple fragrance-free disposable wipes (the Costco ones are great). Put her in a disposable at night (we actually do two disposables, one on top of the other, for nighttime!) See if she stays rash-free (or mostly rash-free) for a few weeks. If so, add back other things you might want (like liners or cloth wipes), one at a time, very slowly. If she gets a rash, cut out the thing you just added back and see if she stays rash-free.
No guarantees, because she might have totally different issues than my DD, but that's what we've been doing! Keep us posted--believe me, I KNOW how frustrating this can be and I don't even want to think of the hundreds of hours I've spent thinking and working on and researching this issue! My DH wanted me to give up just so I'd quit angsting about it.
Yes this happens to us too. I alternate between cloth and seveth generation diapers all day. It's the only way she stays rash free.
No matter what type- I find that the cloth has to be changed pretty fast. Not even 2 hours and there will be red skin.
We had the same problem recently. So DD has been in sposies since. But I spoke with the lady from where I had bought my diapers and she says it might be a soap residue causing the rash...so I am now stripping my diapers with the oxyclean...we'll see if it works.
Memz, with my and mommy of born 01/17/10 and 3
***4** *8***12***16***20***24***28***32***36**40
Astrea, those are some great tips, thank you. We cut out the cloth wipes as well, but I've been using Oxyclean since the beginning with every wash. I like your method of using dish soap + Oxyclean in the hot cycle instead of the cold, I will try that today when I strip our dipes and see how we do.
Also, for anyone in No. Cal who's having this problem whose LO is in 'sposies temporarily, I've found the Full Circle brand diapers from Raley's/Nob Hill to be the BEST 'sposies we've ever used! They're cheap and made with corn too! We've tried every "green" 'sposie, from Seventh Generation to Nature Baby Care to Earth's Best. These are the only ones that not only keep her rash-free, but don't smell weird and give her skin that grayish-brown tint that freaks me out. If I wasn't so committed to CD I'd switch to these permanently
~ Sarah ~ Living the mountain life with DH Dan & DD Lillian 1.6.10 and DS Jack 10.22.11 Trying to find time to !!
Thanks everyone, especially Astrea. I like your method of eliminating everything and then adding back gradually. The diapers are in the wash right now with Oxyclean - I'll keep you posted on how it goes.
make sure the dipes rinse totally clean. S got a horrid rash the first time we used oxi - but not the subsequent times where I double rinsed everything (which I probably should have thought to do the first time 'round ). Could have been a fluke, but who knows?
L, student nurse and married to A, my union man. Happy parents to little S!
I had the exact same experience.
I think disposables are the most absorbent so least rash.
I initially used cotton/hemp prefolds and I think they were not that absorbent plus they created friction on my baby's leg. I switched to the poly fleece stuff and the rash got better.
So now I use disposables at night when the kids are in dipes the longest. I use poly fleece cloth the rest of the time.
I do think the disposables are best for diaper rash so I try to balance this against my environmental concerns. This is the balance I have come up with for us.
I've had both experiences. With my first sehs was very sensitive to wetness but at the same time seemed to get these weird kinda friction rashes from sposies if used all the time.. she also reacted to poly fabics so I needed both all cotton and stay dry which of course doesn't exist.. The best combo turned out to be good assorbant cotton diaper sby day where I could change ASAP and sposies at night.. Our local Kroger diapers turned out to be the best even over all the expensive "green" choices...
My current gets rashy from sposies fast Huggies Supreme (re pack) seem to so far work the best but I have to use then carefully... She however does great in cloth. and handles both all cotton and stay dry well.
I would run the diapers through the wash a couple of times with no detergent. I've read a bunch of articles lately about how people tend to use WAY too much detergent, and that it sticks in the clothes and the washer, which damages the washer and makes the clothes get dirtier faster as stuff sticks to the detergent. If you are using a front load washer you barely need any detergent at all.
It may be worth a shot!
Also, my older daughter had bacterial diaper rashes that also would get a lot better in disposables (though didn't go away entirely). If your washer has a sanitize cycle that would be something to try. We didn't have that when she was in diapers, and the only thing I found that helped (besides changing her like ALL the time) was Calendula ointment, the type in petroleum base. I don't usually like petroleum bases, but it really did seem to help more than the Calendula creams and gels.
Mama to 3 awesome girls: DD1 born 2001, DD2 born 2002, DD3 born March 2011
Yep, here too. DS has always had very sensitive skin, and I'm CONSTANTLY trying to find a diapering system that works for us that doesn't include disposables. So far, I'm no further ahead than when he was a newborn. I've tried only using stay-dry inners, only using suedecloth inners, only cotton, only breathable covers, etc. So many permutations and combinations! Each type of diaper seems to clear up one problem and start another.
Currently our problem is a rash just below his abdomen. It typically clears up at night in the sposie, but by evening the next day is back. Sometimes it's quite red and angry and other times it's just red spots.
For the past couple of days, I've tried putting zinc cream (Aveeno) on the rashy area and then using a disposable liner inside his diaper. So far it seems to be working. I hate having to toss the liner (don't want to wash b/c of the cream, and have a septic system I don't want to overload so I only flush the poopy ones) but much better than tossing a whole sposie. I'm hoping if I can get the rash completely cleared up, I won't have to be so vigilant with the liners and cream - I feel like I'm playing with fire with my diapers at this point.
I would really like him to be exclusively in cloth, but at this point the night-time diaper needs to be a sposie to break the rash cycle. I buy "greener" sposies at least, but don't fool myself that they make much difference.
I have to also agree - PUL diapers are not my son's friend. I use them when we're out and about, but at home, I try to avoid them and use fleece or wool. It makes his skin look SO much better.
(Also, EC helps... quite a bit when I'm on the ball)
Sorry - what's PUL?
We were using Gdiapers (had tons of them given to us before DS was born so figured why not, the cloth version, not disposable) but had similar rash problems. Tried many disposables but have only been able to use 7th Gen as he gets immediate rashes from any others...kind of scary ones with one particular "green" brand - Natural Care I believe...white packaging. Was looking at trying cloth again so I'm interested in what you all have found.
PUL is polyurethane laminated fabric. It's the material that makes most commercial all-in-one diapers and diaper covers waterproof. It's not breathable, though, so babies who are prone to rash get issues because it traps the moisture inside. Fleece and wool are more breathable but less waterproof.
bedsharing, knitting, toddler-nursing, nerdy, babywearing mama!
I would say it's PUL as well. My sons rash cleared up in sposies and then came back when we were in cloth. I experimented a bit and found out synthetic fibers caused the rash and that the PUL just made it worse. So we use fitteds and wool or prefolds/flats with g-diapers. G-diapers have a nylon liner and it is as breathable as wool and causes no rashes. At night we use gdiaper disposable inserts with a hemp or bamboo booster under it because he wakes if he feels wet. Bamboo velour just doesn't cut it for nights.
I find this conversation very interesting. I CD'd my daughter, and now my little guy, and while I knew that disposables definitely kept their bottoms clearer (but at a high cost, IMO), I've never heard anyone say that they found that PUL is a problem. I wonder why there aren't more nylon products out there - I haven't found a nylon pocket at all. I am in the process of buying a couple of Bummis nylon covers, and Kushies makes something they call "taffeta" which is also nylon, but not as good quality, but as far as I know, the only AIO-type with a nylon cover is Bumkins, which I wouldn't say is high quality. I also have a couple of Gdiaper covers that I use with flats but I can see they're not going to last very long in heavy rotation. Has anyone come across any others?
I'm a big believer in fresh air. If i'm home and going to put my baby down for a bit I try to put her on a towel with a naked bum. Towels usually gets peed on and has to go to the wash but rarely pooped on. Harder to do now that she snake crawls off the towel. Baby also spends a fair amount of time with a loose trifold diaper between my lap and her bum but not hooked. Mostly she's in CD and they do get damp from one pee which is sooner than I change her
I'm just here to commiserate and second what most posters have said. I cd my older son for a year when all the sudden we started having yeast issues and I couldn't beat them, even after trying what others have posted with the addition of sunning the dipes for DAYS in hopes to get rid of any yeast. So he has been in sposies for 6 months now and so is our newborn son right now too because he already has a rash and I don't want to exacerbate it.
I have hundreds of dollars of diapers just sitting her looking cute and crying out to be used! So frustrating!
And dh is soooo not on board about going back to cloth because he's gotten use to the laziness of sposies. Some how the huge amount of money we're spending on sposies doesn't seem to bother him!
We think green! Gentle mama to 3 amazing kiddos. Recovering from religion.
LIFEschooling. Extended NAKing. Graduated cloth diaperer.
What I've found with both my kids (who have both been mainly CD but with periods of DD), is that they get fewer rashes overall when wearing CDs, but if they do get a rash it clears up faster with DDs. If they get a rash when wearing DDs (which they both did - and horrible ones) then those rashes clear up when wearing CDs. In fact, that's what got me started on CDs when my oldest child was a baby - recurrent bad diaper rashes that wouldn't clear up.
PUL is polyurethane laminated fabric. It's the material that makes most commercial all-in-one diapers and diaper covers waterproof. It's not breathable, though, so babies who are prone to rash get issues because it traps the moisture inside. Fleece and wool are more breathable but less waterproof.
Wool diaper covers don't leak unless they need to be lanolized. I just wanted to put that out there, lest anyone think they'd be trading breathability for dry clothes. That's not the case at all. Fleece covers can have compression leaks, but I'm on baby #2 now and have used nylon, wool, PUL, fleece, specially coated cotton, and every other kind of cover there is, I think. Wool covers will not result in wet clothes unless your diaper isn't absorbent enough, in which case your PUL would leak anyway, or unless you need to add lanolin to the cover. However, in the case of not enough lanolin, you'll know well before you get to the leaking stage that you need to add it, simply by the fact that the outside of the cover will start to feel the tiniest bit damp when the diaper is soaked. I've literally never had a leak with wool, although I've had them with every other type of cover and disposables. :)
I tried wool (that expensive Danish brand, Lana something) covers (soakers, I guess?) with Willow at night a few times. I lanolized them well before using, and they were secondhand and had been cared for before that by a knowledgeable mama, but she leaked through them every time. She never leaked through at night before that (and I used the exact same stuff inside the wool as I used inside her PUL covers), and she never has since, except sometimes in sposies if I forget to double them up.
Are you supposed to use wool with no clothing overtop of it?
I've noticed rashes when I use too much detergent. I try to keep a balance between too much (which causes red butt) and too little (which causes stinky diapers).
I'm on #4 in cloth diapers and we absolutely do not have to use sposies ever. Here is what works and is important for us:
1. My kids need stay-dry cloth diapers. FuzziBunz, Rumparooz and bumGenius one-size pockets are our favorite. These all have PUL outers but we have no problems at all. Prefolds will give us a rash, even with wool or fleece covers.
2. We have to use a cloth diaper detergent. I have been fine with Vaska, Rockin Green, bumGenius and Allens. Tide caused the mother of all rashes.
3. You cannot use a lot of detergent. We use 1 Tablespoon for 40 diapers. REALLY. Almost everyone I see with problems IRL is using way too much or the wrong detergent.
4. We wash the pocket diaper shells on hot in a separate load b/c they need so little detergent (1 tsp.) and they cannot handle the Sanitary cycle.
5. We wash the pocket inserts and wipes on Sanitary with 1 Tbsp. detergent and some "free" oxygen bleach.
6. For both loads, we do two cold rinses and then a hot rinse.
7. Once a month, I bleach the pocket inserts with 1 Tbsp chlorine bleach as we have well water with no chlorination.
8. Toddlers need to be changed often, even though they are busy and don't want to be changed. Toddler pee is stronger and before you know it, 5 hours will have passed and their pee will have given them an ammonia rash.
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We're getting to be a cynical and jaded lot, many of us out here in the electorate. It's reached the stage where some of us would rather sit through six episodes straight of Big Brother than face another appearance by a politician of any stripe. Closer to the actual election, make that 10 episodes of Big Brother.
Anyway, it made me think about what makes a successful politician and I've come up with 10 easy steps.
Firstly, the records show being male goes a long way. You are less likely to be lampooned for your clothing and hairstyle choice, apart from for the colour of your ties.
Learn to smile, smile, smile. The skill is in cultivating a smile that fully extends to the eyes and thus appears genuine. Avoid a mere baring of teeth that will forever be associated with a certain NSW ex-pollie pursued by a relentless media.
Say what you have to say in a tone that expresses authority without being arrogant, is friendly without being smarmy. Have a few handy phrases (oh, definitely don't call them slogans) up your sleeve. Having learned them say them over and over, while our frustration level goes up and up.
I don't have to tell you about kissing babies. You learned that in Kindergarten for Pollies classes. But do aim to kiss the baby, not the mother. Likewise be prepared to eat whatever is proffered to you at a sausage sizzle or shopping centre. Just chew, swallow and smile.
If you are in government, become skilled at statements that in one breath tell us our country could be better, but of course you've still done a great job in the past three years. If in opposition, tell us the country is in a terrible mess, but it will only take you winning the election to fix everything.
Surround yourself with family whenever possible. Give them drills in perfecting that same genuine smile. Come across as ordinary, throw in a few Aussie idioms. But let shine that indefinable aura that marks you out for leadership.
There, that's it. Oh, if you dispute there aren't 10 steps here, the final one is to be rubbery with figures.
Joan Brown
Heckler wants readers to focus their infuriation on electoral matters until polling day. Send your 400 words of ballot bile to firstname.lastname@example.com
Read at smh.com.au/comment


text:
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
Adjuvants are crucial components of vaccines. They significantly improve vaccine efficacy by modulating, enhancing, or extending the immune response and at the same time reducing the amount of antigen needed. In contrast to previously licensed adjuvants, current successful adjuvant formulations often consist of several molecules, that when combined, act synergistically by activating a variety of immune mechanisms. These "combination adjuvants" are already registered with several vaccines, both in humans and animals, and novel combination adjuvants are in the pipeline. With improved knowledge of the type of immune responses needed to successfully induce disease protection by vaccination, combination adjuvants are particularly suited to not only enhance, but also direct the immune responses desired to be either Th1-, Th2- or Th17-biased. Indeed, in view of the variety of disease and population targets for vaccine development, a panel of adjuvants will be needed to address different disease targets and populations. Here, we will review well-known and new combination adjuvants already licensed or currently in development—including ISCOMs, liposomes, Adjuvant Systems Montanides, and triple adjuvant combinations—and summarize their performance in preclinical and clinical trials. Several of these combination adjuvants are promising having promoted improved and balanced immune responses.
Adjuvants are crucial components of vaccines, both for human and animal applications. Adjuvants were initially developed empirically by co-formulating vaccine antigens with a variety of molecules including oils, salts, and carbons. Our growing understanding of the immune system, however, and in particular the innate immune system, has enabled us to develop adjuvants according to a more rational and focused approach rather than through "trial and error." Indeed, adjuvant research has become an integral part of vaccine development. It combines a variety of disciplines, including chemistry, biochemistry, molecular biology, and immunology. Many novel adjuvant technologies have been developed or are in the pipeline for future vaccine candidates. Such novel technologies include combination adjuvants, which consist of more than one adjuvant component and which often act synergistically by stimulating and activating a variety of cells and immune mechanisms. Here, we will review several of the best-known combination adjuvants, including liposomes, ISCOMs, montanides, nanoemulsions and Adjuvant Systems, and summarize their performance in preclinical and clinical trials.
Cationic liposomes have been studied for many years as delivery vehicles/adjuvants. Liposomes protect antigens from degradation, deliver them to antigen presenting cells (APCs), and can be used for mucosal delivery. Many liposomes mediate retention of the vaccine at the site of delivery, and some have immunostimulatory properties, although frequently other compounds such as toll-like receptor (TLR) ligands need to be incorporated for optimal adjuvanticity. Cationic liposomes may contain the following lipids: dimethyldioctadecylammonium (DDA), 3-(
DDA has been used as adjuvant in animal trials since 1966 [
MPL (a TLR4 ligand) and MMG, two of the other compounds combined with DDA, are both found in bacterial cell walls and promote Th1-biased immune responses. MPL is derived from LPS, a TLR4 ligand, and when included in an Ag85B-ESAT-6—DDA liposome formulation, it enhanced protection against tuberculosis both in mice and in cynomolgus monkeys [
DOTIM was originally used for
Liposomes and TLR agonists: Clinical studies.
|Vaccine antigen
|No study results posted
|ClinicalTrails.gov identifier NCT00922363
|HIV peptide cocktail AFO-18
|Induction of T-cell responses in some of the vaccinees; no significant changes in viral load or CD4+ T cell counts
|ClinicalTrials.gov identifier NCT01141205 [
|JVRS-100 adjuvant
|No study results posted
|ClinicalTrials.gov identifier NCT00662272
|JVRS-100 adjuvant
|No study results posted
|ClinicalTrials.gov identifier NCT00936468
Immune stimulating complexes (ISCOM) are ring-like structures containing cholesterol, phosphatidylcholine and saponins, mostly QuilA. ISCOMs have been tested in a variety of species, including small and large animals. The actual ISCOM matrix can directly associate with antigens or be formed first and then added to the formulation at a later time. An important advantage of ISCOMs is their excellent stability for over one year at 4 °C. While the exact mechanism of action is still unclear, ISCOMs have proven to be highly effective when delivered via mucosal surfaces.
ISCOMs interact with dendritic cells (DCs) and can enhance cross-presentation of the incorporated antigen [
ISCOMs and IC31®: Preclinical and clinical studies.
|Individuals with advanced melanoma
|Study ongoing
|ClinicalTrails.gov identifier NCT 00518206
|ISCOM and PANFLUVAC
|Healthy Adults
|Study ongoing
|ClinicalTrails.gov identifier NCT00868218
|IC31®/Ag85B-ESAT-6 (TB vaccine)
|Neonatal murine model
|↓ Bacterial growth, differentiation of CD4+ T cells into multifunctional Th1 and Th17 cells secreting IL-2, TNF-α and IFN-γ, antigen-specific DCs expressing co-stimulatory molecules CD80, CD86 and CD40 in the DLNs
|IC31®/Ag85B-ESAT-6 (TB vaccine)
|Cynomolgus macaques
|↓ Clinical infections and prevents reactivation of latent infections
|IC31®/Ag85B-ESAT-6 (TB vaccine)
|Cynomolgus macaques
|↓ Clinical infections and prevents reactivation of latent infections
|IC31®/Ag85B-ESAT-6 (TB vaccine)
|Healthy mycobacterially naïve individuals
|Potent and persistent antigen-specific IFN-γ+ T-cell responses, sustained for 2.5 years
|IC31®/Ag85B-ESAT-6 (TB vaccine)
|Prior TB-infected individuals
|Strong antigen-specific T-cell responses, sustained for 32 weeks
|IC31®/H1N1 (Influenza vaccine)
|Young and aged mice
|↑ HI titers, IgG2a Abs and IFN-γ producing CD4+ T-cell responses, sustained for 200 days after a single dose vaccination
|IC31®/HSV-2 (Genital herpes vaccine)
|High neutralizing HSV-specific Ab responses and splenic IFN-γ responses
Montanide-based adjuvants have been used in both veterinary and human vaccines. These oil-based formulations have been successfully commercialized and are now available for animals in a vaccine against FMD. For human application, Montanide-based therapeutic vaccines have been developed for cancer [
Montanides can be improved by combining them with other adjuvants or immune modulators. An example of a Montanide-based adjuvant is the Incomplete Seppic Adjuvant (ISA™, SEPPIC Inc. Fairfield, NJ, USA), which acts as oil-emulsion adjuvant, and which has been tested in combination with a number of experimental vaccines including a malaria vaccine [
Montanides have been evaluated in several clinical trials. For example, the Montanide ISA 51 was tested in combination with cancer antigens and cytokines including an evaluation of the effects of local Granulocyte-Macrophage Colony Stimulating Factors (GM-CSF) on skin DCs in melanoma patients [
Polycationic peptides enhance cellular uptake of proteins or bacterial DNA by cells [
Based on the ability of cationic compounds to enhance uptake, IC30 was combined with CpG ODN, a TLR9 agonist. The combination of IC30 and CpG ODN induced stronger antigen-specific T cells responses, which were detectable even one year after injection [
The two components of IC31®, KLK and ODN1a, act via different mechanisms. Subcutaneous injection of fluorescent-labeled OVA, KLK, and ODN1a in mice led to depot formation at the site of injection, which was detectable up to 58 days after injection. However, co-administration of fluorescent-labeled OVA and ODN1a resulted in rapid clearance from the injection site, indicating the potential of KLK to induce a depot at the injection site [
Being the only professional APCs, DCs are specialized in processing and presenting antigens to naïve T cells and induce activation of antigen-specific immune responses [
Various combination adjuvants consisting of a variety of molecules have been developed in recent years and are currently being tested in preclinical trials. This includes both dual and triple combinations and includes polymers such as poly(lactic-co-glycolic) acid, chitosan and polyphosphazenes [
Adjuvant systems™ (GlaxoSmithKline (GSK)) are various combinations of classical adjuvants and immunostimulators specifically designed to tailor the adaptive immune responses against specific pathogens in a target population including children, elderly and immunocompromised individuals. Various adjuvant systems have been developed and a few are in clinical trials. AS03 and AS04 have already been licensed for use in humans. AS03 was approved for H5N1 prepandemic and H1N1 pandemic influenza vaccines and AS04 for human papilloma virus (HPV) (Cervarix™) and hepatitis B virus (HBV) (Fendrix®). AS04 was also licensed for herpes simplex virus (HSV) but was recently terminated due to low efficacy in clinical trials [
The TLR4 agonist lipopolysaccharide (LPS) is a potent adjuvant but it is very toxic and causes septic shock. MPL is a "detoxified" derivative of LPS isolated from the Gram-negative bacterium
When combined with alum, MPL still retains its ability to interact with TLR4 and activate innate immune responses. This leads to activation of NF-κB and transient production of pro-inflammatory cytokines (IL-6, TNF-α, and IFN-γ) and chemokines, such as CCL2 and CCL3 at the injection site [
Since water-in-oil emulsions were too reactogenic for use in humans, GSK developed AS03, an oil-in-water emulsion. AS03 consists of
Injecting antigen and AS03 72 h apart or in different limbs resulted in reduced influenza-specific antibody titers suggesting that AS03 adjuvant activity depended on the spatial and temporal co-localization with the antigen [
AS02 is a combination of oil-in-water emulsion with MPL and QS21 (MPLA+QS21+o/w emulsion) and was initially developed for malaria vaccines. QS21 has been shown to induce antigen-specific antibody, cell-mediated and CTL responses, including development of immunological memory in nonhuman primates [
Adjuvant system (AS): Clinical studies.
|AS04/HPV-16/18 (CervarixTM)
|Girls and women (10–75 years)
|Ab responses in serum and cervicovaginal secretions up to 36 months
|>8,000 women (15–25 years)
|Vaccine efficacy 92.9% against cervical intraepithelial neoplasia grade 2 and above (CIN2+) 34.9 months post vaccination and high vaccine efficacy against CIN2+ associated with 12 non-vaccine oncogenic strains (cross-protection)
|HIV-seronegative young African girls (10–25 years)
|100% seroprotection, which sustained up to 12-month post-vaccination, high neutralizing Abs and total IgG titers sustained for 8.4 years post-vaccination
|Young girls (9–15 years)
|Co-administered HPV-16/18/AS04 with inactivated hepatitis A and B (HAB) or dTpa-IPV: immunogenicity was no inferior than any of the vaccine alone
|AS04/HBV (Fendrix®)
|Elderly, immunocompromised and renal insufficiency patients
|Rapid and high seroprotection at 3 month (74%
|AS03 + Influenza A (H1N1 vaccine)
|II and III
|Volunteers (18–60 years), high-risk elderly (61–88 years) and children (3–9 years)
|Higher seroconversion levels and 4-fold Ag-sparing effect compared to nonadjuvanted vaccine, ↑ H1N1 specific CD4+ T cells
|AS03 + Influenza A (H1N1 vaccine)
|Children (6 months–12 years)
|Higher immunogenicity compared to nonadjuvanated vaccines
|AS03 + H1N1 influenza pandemic vaccine 2009
|Multiple populations
|Vaccine efficacy: 72%–97%
|AS02+RTS,S (Malaria vaccine)
|131 semi-immune adults
|Vaccine efficacy: 71% in 9 wks, strong Ab and T-cell responses to CSP
|2,022 children (1–4 years)
|Vaccine efficacy: 29.9% for first clinical episodes and 57.7% for severe malaria. Vaccine efficacy: 48.6% at 18 months for several malaria cases
|AS02 + Mtb72F (TB vaccine)
|Purified Protein Derivative (PPD)-negative adults (18–40 years)
|↑ Humoral and polyfunctional CD4+ T-cell responses expressing CD40L, IL-2, TNF-α and IFN-γ, sustained for 9 months and 1 year after primary and booster immunization, respectively
|450 healthy individuals Renal insufficiency patients; inprior HB vaccinated individuals
|High seroprotection rates after first (75.9%) and second vaccine doses (99.7%) Seroprotection rate (76.9%) Seroprotection rates were 89.0% one month post-booster vaccination
|Advanced tumor patients, Lung cancer patients
|Anti-MAGE-A3-specific Ab responses in 96% of the advanced tumor patients and 30% patients showed ↑ IFN-γ responses
|AS01/RTS,S (malaria vaccine)
|Rhesus monkeys
|↑ Ag-specific Ab and IFN-γ producing Th1-type responses
|AS01/MSP-1 (malaria vaccine)
|102 healthy human volunteers
|Vaccine efficacy was higher (50%) compared to RTS,S/AS02A vaccine; ↑ CSP-specific IgG titers and polyfunctional CD4+ T cells expressing IL-2, IFN-γ, TNF-α, or CD40L
|AS01/M72 (TB vaccine)
|110 PPD-negative human volunteers
|Vaccine specific Th1 CD4+ T-cell responses compared to M72/AS02 vaccine
|AS01/M72 (TB vaccine)
|540 children, aged 5–17 months
|RTS,S/AS01E induced higher CD4+ T-cell responses as compared to RTS,S/AS02D
|AS01/F4 (HIV-1 vaccine)
|180 healthy volunteers (18–40 years)
|High frequencies of polyfunctional CD4+ T-cell responses characterized by CD40L, IL-2 in combination with TNF-α and/or IFN-γ, which persisted for 44 days post-vaccination.
Malaria vaccine adjuvanted with AS02 has shown great promise. However, to further increase the efficacy and to eliminate the infected hepatocytes, the AS01B adjuvant system has been evaluated by GSK. The AS01 adjuvant system is a liposomal formulation comprised of immune-stimulants MPL and QS21 (MPLA+QS21+a liposomal suspension). When tested in rhesus monkeys, RTS,S/AS01 elicited higher antigen-specific antibody and IFN-γ producing Th1-type responses compared to any other adjuvant formulations [
In view of the strong induction of cell-mediated immunity, AS01B was also evaluated in a human clinical trial with a TB vaccine in comparison to AS02. In this study, M72 antigen was formulated with either AS02 or AS01. While both M72/AS01 and M72/AS02 had an acceptable safety profile and elicited robust polyfunctional M72-specific CD4+ T-cell and antibody responses, the highest CD4+ T-cell responses were induced by M72/AS01 [
Nanoemulsions have a mean droplet diameter of 50–1,000 nm and are particularly suited to mucosal delivery. Although not as extensively studied as liposomes, one nanoemulsion is licensed and several have progressed to human clinical trials. One of the best characterized nanoemulsions is MF59, an oil-in-water emulsion of ~250 nm consisting of the metabolizable oil squalene, Tween-80 and Span 85 (reviewed in [
Two other oil-in-water nanoemulsions, when formulated with smallpox, HIV-1, influenza, or hepatitis B antigens and delivered intranasally, mediated the production of not only robust virus neutralizing antibodies, but also IFN-γ and TNF-α, as well as elevated IgG2a and mucosal IgA levels. These oil-in-water emulsions, designated W205EC and W805EC, consist of 1% cetyl pyridum chloride (CPC), 5% Tween 20 or Tween 80, 8% ethanol in 64% soybean oil and 22% water (NanoBio Corporation, Ann Arbor, MI, USA). When formulated with smallpox, HIV-1, influenza, or hepatitis B antigens and delivered intranasally, these adjuvants mediated the production of not only robust virus neutralizing antibodies, but also IFN-γ and TNF-α, as well as elevated IgG2a and mucosal IgA levels. W805EC was evaluated in a human clinical trial with Fluzone®, which demonstrated that this adjuvant is well tolerated. Volunteers received a single intranasal dose with increasing antigen and adjuvant amounts. The highest dose (10 µg) of antigen in combination with 20% W805EC, induced increased serum hemagglutination inhibition antibodies reactive with three influenza strains, as well as antigen-specific IgA in the nasal wash [
MF59 has been combined with either a CpG ODN or a TLR4 agonist, E6020, in an influenza soluble trivalent egg-derived antigen formulation. While addition of CpG ODN or E6020 to MF59 did not increase influenza-specific antibody titers, a shift towards a more Th1-biased response was observed which suggests that co-formulation of MF59 with a TLR ligand may tailor the immune response to be more Th1 biased [
Many of the vaccines that have been recently developed, or will be in the future, consist of highly pure pathogen-derived antigens. This approach is necessary for vaccine development against live-threatening infectious diseases and cancers. For these antigens to induce robust immune responses, formulation with adjuvants is critical. Adjuvants can enhance the speed and magnitude of the development of immune responses, reduce the amount of antigen and/or vaccinations needed, increase cross-protection and reduce non-responsiveness, in particular of specific populations such as the very young or elderly. In view of these multiple roles, the current trend in vaccine formulation against both cancer and infectious diseases is to include at least one and often multiple components to engage PRRs, and thus activate the innate immune response, as well as at least one compound that stabilizes or targets antigens to the appropriate immune cells. Engagement of PRRs by their ligands is critical for induction of the innate immune response which then directs the adaptive immune response to be either Th1-, Th2- or Th17-biased. This ability to tailor the immune response is particularly important for vaccine development against difficult targets such as chronic bacterial or viral infections and cancer. Several classes of PRRs have been identified, including TLRs, NOD-like receptors (NLR), RIG-I-like receptors (RLRs) and C-type lectin receptors (RLRs). As described in this review, TLR agonists have been most extensively studied as adjuvants ands shown to be very promising. The TLR agonists often act synergistically with other classes of adjuvants used in the formulation or even with other TLR or NLR agonists. In fact, it is now known that one of the most effective vaccines, the live-attenuated yellow fever vaccine, activates multiple DC subsets through TLR2, TLR7/8 and TLR9, which leads to a robust balanced immune response. Aluminum salts and muramyl-dipeptides are two examples of NLR agonists used in licensed vaccines and clinical trials, respectively, and as more agonists of these additional classes of PRRs are identified, we can expect more to be tested as adjuvants.
Currently there are four licensed vaccines that contain multiple TLR agonists, BCG that contains TLR2 and TLR4 agonists, Cervarix and Fendrix that contain alum and MPL, and Cadi-05 (Immuvac) (
In this review we summarized recent and relevant information about many known and new adjuvant combinations including ISCOMs, liposomes, Adjuvant Systems, Montanides and triple combination adjuvants is clear that combinations of adjuvants have multiple advantages, and are critical to achieve the desired degree of vaccine efficacy against many new, challenging disease targets. Furthermore, there is strong evidence supporting inclusion of at least one PRR agonist. As these pathogens target different organs and tissues and cause different types of pathogenesis, there likely will be a need for a panel of combination adjuvants for specific disease targets, routes of delivery and/or populations. As recently described [
Research in the authors' laboratories is funded from a variety of funding agencies including the Canadian Institutes of Health Research (CIHR), the National Science and Engineering Research Council (NSERC), the Saskatchewan Health Research Foundation (SHRF), the Alberta Livestock and Meat Agency (ALMA), the Saskatchewan Agriculture Development Fund (ADF), the Pan-Provincial Vaccine Enterprise and the Krembil Foundation. The manuscript was published with permission of the Director of VIDO as manuscript #675.
B. Levast wrote the ISCOM and IC31 sections, S. Awate wrote the adjuvant systems section, L. Babiuk critically read the review, G. Mutwiri wrote the Montanide section, V. Gerdts wrote the introduction, IC31 and triple adjuvant sections and S. van Drunen Littel-van den Hurk wrote the liposomes, nanoemulsions and conclusions sections and was responsible for the final submission.
The authors declare no conflict of interest.


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Should Professor Horatio Kharon's dancing man counterpart have I seperate page? They're kind of like independent characters. The dancing man actually spoke while Horatio Kharon is just a picture. I'm sure if the author actually appeared in the flesh they'd probably be voiced by the same person, but at the moment if we made on page for them the voice actor section would be referring to his dream counterpart. I don't know if this would matter to some? I guess could make my own conclusions, but I'd be interested to hear what some of you have to say. -- Anythingspossibleforapossible (talk) 09:17, April 1, 2013 (UTC)
- I've seen "Nightmare in Red" in Spanish, and I would recommend not separating them based on that episode. --RockSunner (talk) 15:44, April 1, 2013 (UTC)


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Southfire Systems Inc.6984 NW 173rd Drive Suite #610Miami, FL 33015ph: (954)-520-5940fax: (305) firstname.lastname@example.com
...a new approach to building customer dedication...
Affordable, top-quality fire and security alarm sales, support and service. Offering low-cost monitoring, inspections, installation and maintenance from the most basic to the most advanced needs of customers throughout the South Florida area.
2007 Copyright Southfire Systems, Inc. All rights reserved.


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Anathema_P... Photographer
Elle DegenerateModel Female Richmond, Virginia, US
My MM URL: http://www.modelmayhem.com/EllenDegenerate
Mayhem # 668877
About Me
I stopped modeling for a while but am looking to get back into it on the side. I work full time as a manager at a clothing store so mondays and tuesdays are really the best times to shoot (my usual days off) otherwise it needs to be planned 2 weeks or more in advance.
Tattoo wise I have two traditional style revolvers on my abdomen in between my hips with a banner around each, one reading east the other punks, on my back in between my shoulder blades I have a large celtic trinity with the words "Creator, Inspirator, Mother" surrounding it and a banner above that says "Edita", on my left upper arm I have a rockabilly zombie girl with a banner around her that reads "Brains and Beauty" and underneath the portraits of Buddy Holly, Johnny Cash, and Elvis Presley in zombie form with a blood splattered leopard print background. I also have a 50's styled microphone with a banner around it that says cold hearted on the center of my chest.
piercing wise I have a spider bite on my nose (two piercings close together), two facial anchors under my right eye (they basically sit under the skin with screw on toppers, mine are pink gem stones) and my ears are pierced
Any nude shoots I do have a fee but I am willing to negotiate so just message and ask
Concept I want to shoot:
-sexy zombie girls (maybe a calander?)
-demented alice in wonderland
-sex,drugs,rock N' roll
PLEASE PLEASE PLEASE!!!!! like my facebook fan page. I started it a couple months ago and am finally getting around to trying to use it and I need 25 likes total to get an actual URL for it. The link is up at the top with my name labeled Facebook Fan Page
Have you worked with Elle Degenerate? Add Credits for Elle Degenerate! >>
Anathema_P... Photographer
SickMedia Photographer
Cara Jean VA Model
Feygin Foto Photographer
Urdaneta Photography Photographer
Swartz Photography Photographer
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Democracy Now! is a non-profit organization funded through individual donations and foundation
grants. We do not accept any corporate underwriting, advertising, or government support. Your support is vital to
sustain and grow Democracy Now!
Congolese Citizens Caught in Crossfire of Battle for Region's Lucrative Resources
Bush Admin Pushes Through Last-Minute Deregulation that May Be Hard to Undo
Michelle Obama's Biographer on Nation's First African American First Lady
Democracy Now! is a 501(c)3 non-profit news organization. We do not accept funding from advertising, underwriting or government agencies. We rely on contributions from our viewers and listeners to do our work. Please do your part today.


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|City Receives Excellence Award for DPR Project
The City of Wichita Falls received the Municipal Excellence Award from the Texas Municipal League for the Direct Potable Reuse Project during the TML open general session at the 103rd annual TML conference being held in San Antonio. Complete Story
| In this section you will find helpful information about the Wichita Falls Public Works Department. The department consists of four divisions and four water related divisions:


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The Procedure Committee, in its first report of 1996 (PP 194/1996), recommended a scheme for the interpretation and application of section 53 of the Constitution, based on the foregoing analysis. Essentially, the scheme would require bills which appropriate money, either directly or indirectly, to contain an appropriation clause and to be first introduced into the House of Representatives, and bills which increase taxation to be treated as bills imposing taxation, and would provide for certifications by the government as to whether particular amendments moved in the Senate would increase expenditure from an indefinite appropriation, with statements of reasons for such certification. This proposal has not yet been adopted by the Senate.
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text: Translation of Chinese calligraphy in English Translation Traductor Traduction Tradutor Traduttore Übersetzung Перевод Μετάφραση Çeviri لترجمة 翻訳 번역 Översättning การแปล Oversættelse Traducere Переводити Oversettelse Tłumaczenie अनुवाद Fordítás Vertalen תרגום ترجمه Translation Dictionary Thesaurus Tools Chinese calligraphy Translation Online Translation > English Translation > Chinese calligraphy Translation Babylon 10 The most popular translation software Download it's free Local Translation: Traductor Traduction Tradutor Traduttore Übersetzung Перевод Μετάφραση Çeviri لترجمة 翻訳 EnglishFrenchItalianGermanPortugueseSpanish--------------ArabicCatalanCastilianCzechChinese (s)Chinese (t)DanishGreekHebrewHindiHungarianPersianJapaneseKoreanDutchNorwegianPolishRomanianRussianSwedishTurkishThaiUkrainianUrdu To Choose A LanguageEnglishFrenchItalianGermanPortugueseSpanish--------------ArabicCatalanCastilianCzechChinese (s)Chinese (t)DanishGreekHebrewHindiHungarianPersianJapaneseKoreanDutchNorwegianPolishRomanianRussianSwedishTurkishThaiUkrainianUrdu Full Text Translation Dictionary definition of Chinese calligraphy Synonym of Chinese calligraphy in thesaurus More Languages:[top] Chinese calligraphy Translation On Other Language: English Get Babylon's Translation Software Free Download Now! Chinese calligraphy in English Chinese calligraphy is a form of calligraphy widely practiced in China and revered in the Chinese cultural sphere, which often includes Japan, Taiwan, Korea and Vietnam. The calligraphic tradition of East Asia originated and developed from China. There is a general standardization of the various styles of calligraphy in this tradition. Chinese calligraphy and ink and wash painting are closely related, since they are accomplished using similar tools and techniques. Chinese painting and calligraphy distinguish themselves from other cultural arts because they emphasize motion and are charged with dynamic life. According to Stanley-Baker, "Calligraphy is sheer life experienced through energy in motion that is registered as traces on silk or paper, with time and rhythm in shifting space its main ingredients." Calligraphy has also led to the development of many forms of art in China, including seal carving, ornate paperweights, and inkstones. See more at Wikipedia.org... Copyright: © This article uses material from Wikipedia® and is licensed under the GNU Free Documentation License and under the Creative Commons Attribution-ShareAlike License Dictionary source: Wikipedia English - The Free Encyclopedia More: English to English translation of Chinese calligraphy Babylon Products Popular Translation Premium dictionaries About Babylon Online Dictionary Online Translation Online Thesaurus Webmaster tools Translation Software Human Translation Learn a Language English for Kids Translation Apps spanish translation english to spanish translation spanish to english translation french to english translation english to german translation Oxford Dictionary Merriam Webster Dictionary Encyclopaedia Britannica Privacy Policy Terms of Use Sitemap Copyright © 2014-2017 Babylon Software Ltd. All Rights Reserved to Babylon Translation Software


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Ross William Ulbricht has been indicted on charges he was the mastermind behind the secret website Silk Road, which brokered more than $US1 billion in transactions for illegal drugs and services.
An indictment unsealed in New York on Tuesday charged Ulbricht with drug trafficking, computer hacking, money laundering and other counts. Ulbricht's attorney said his client will plead not guilty at an arraignment scheduled for Friday.
The 29-year-old Ulbricht was arrested late last year; he denied the charges at the time. Authorities say he operated the Silk Road site under the name "Dread Pirate Roberts", an apparent reference to the movie The Princess Bride.
The website allowed users to anonymously browse through nearly 13,000 listings. Authorities say the categories included "Cannabis", ''Psychedelics" and "Stimulants." Purchases were made using the virtual currency bitcoin.


text:
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S33 Ep30: 2015 Subaru WRX & 2014 Chevrolet Camaro SS 1LE
Video duration: 26:48Expires: 04/07/15Video has closed captioning.
In this episode, we get track-happy in Subaru's rebooted WRX. We'll see if an up-to-date Chevrolet Camaro is still up to the challenge. Our Success Story this week profiles an off-site airport shuttle bus company in Atlanta, Georgia. We explore how men and women think differently when shopping for a new car. Pat Goss buffs up our know-how down at Goss' Garage.


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Mobile Device Security Best Practices
Your tablet, smart phone, or e-reader is easy to use around campus because it is portable. However, it also carries a risk of being lost, stolen or misplaced. In addition, such devices may have weak authentication mechanisms that can be compromised or easily disabled. The risk to you and The University of Chicago is even greater if the device can access and store confidential data, or what the University has defined as sensitive data.
In order to help mitigate the risk, we provide guidance on actions you should take to protect your own data and that of others.
General Security
- Password protect your device and enable auto-lock. Choose the strongest password that your device can support.
- Consider using an image that provides a contact point should someone find your device and wish to return it. For example, the "If Found Lock Screen" for Apple products.
- Follow standard security protocols, such as making sure all operating system and application updates and patches are installed.
- Wipe the data on your mobile device before disposing of it. Also enable a remote wipe feature in case you have to do so if it is lost. This may include features that will delete stored data on your mobile device if a password is entered incorrectly after a certain number of times. Check with your mobile device provider for specific information concerning your device. Users of who are running Microsoft Exchange (xMail) on their mobile device can wipe an entire device when removing their xMail data remotely. Blackberries have to be using ITS xMail services and use Blackberry Enterprise Services (BES) for syncing. To request a data wipe, email IT Services or call 773-702-5800. Some devices may be listed, but their support varies by official phone vendor. Jailbroken, rooted, non-manufacturer ROM-based devices may not respond to the wipe command.
- Report lost, stolen, or misplaced mobile devices to the police immediately. Wipe its data remotely. If your mobile device contained UChicago sensitive data email IT Security or call 773-702-2378 immediately. For technical assistance email the ITS Service Desk or call 773-702-5800.
Transmission Security
- Disable wireless access, such as Bluetooth or Wi-Fi, etc., when not in use to prevent unauthorized wireless access to the device.


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Avalon Doily by Kathryn White
Welcome! You are browsing as a guestWould you like to see 4 projects made from this pattern and much more? create a free account What am I missing?
Avalon Doily
This pattern is available from e-patternscentral.com for $2.49.
Errata available: e-patternscentral.com
Skill Level: Intermediate
• DMC Cebelia size 20 crochet cotton
(415 yds per ball):
100 yds each #210 violet
and #712 cream
75 yds #524 light green
• Size 9/1.25mm steel crochet hook
or size needed to obtain gauge
Rnds 1–7 = 13/4 inches; Flowers 1–24 = each 7/8 inch in diameter; Large
Flowers 1–24: each 11/2 inches in diameter
For more information, see: https://www.e-patternscentral.com/detail.html?prod_i...


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Beginning Sounds Match-Up: Put It Away
What do box, book, and ball have in common? They all have the same beginning sound! Start your preschooler on the road to phonics success with this worksheet that asks him to match the pictures with the same beginning sound.
© Learning Horizons Inc. All rights reserved.
Click to find similar content by grade or subject.


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Angelina Jolie With Twins Vivienne and Knox in Malta
Angelina Jolie Has the Twins in Her Arms and Shiloh by Her Side For Another Bowling Day
Start Slideshow
Angelina Jolie Has the Twins in Her Arms and Shiloh by Her Side For Another Bowling Day
Angelina Jolie carried both Knox and Vivienne in her arms and Shiloh walked closely behind as they left a bowling alley in Malta today. Angelina also brought all six kids to the lanes last week as they explore the local attractions, like the water park where the whole Jolie-Pitt family was pictured together. Pax and Maddox got another special treat when the two older Jolie-Pitt boys visited Brad Pitt on the set of World War Z over the weekend. Their overseas stay may be all about Brad's work schedule, but Angelina is currently grabbing the spotlight for her own career. Angelina Jolie was one of the highest-paid actresses last year with both she and Sarah Jessica Parker earning $30 million each.


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I am basically a hill walker gone wrong. Happily making my way round the Munros minding my own buisness. A friend of mine mentioned to me that he was a climber and did I fancy coming out. Two years later and I am cragging, doing easy mountain routes and now winter climbing. Munro tally has come to a shuddering halt!
Best Climbing Experience
Climbing my first grade 3 with my good mate Bobby Motherwell!
Recent Postings
Interests Outside Climbing
Got a young family no time for anything else!
Photo Gallery
Click to view Areteroute's gallery. (5 photos)
Click to search for photos of climbers called Areteroute.
Click to list photo comments written by me. (6 comments)
I've voted for 4 photos, average vote 4.2.
(25% superb - 75% good - 0% average - 0% poor - 0% rubbish)
Anything Else We Should Know
Yeah, please say hello and engourage me as I try and drag my sorry ass up some snow filled gully or ice covered crag, cause I am scared and kind words help!!!!!!!!!!!
Been Climbing For
4 to 10 years
Best Onsights
Winter - II/III
Main Sport/Activity
Favourite Crag/Rock
Quad rocks Largs
I Climb...
Most weekends
In the UK
Favourite Climbs
Anything in Glencoe!
Latest Climbs
West Gully III
Chockstone Gully II
Summit Gully II
Pinkerton's Corner S
Kristeen's Crack VD
Strawberry Crack S
Broken Arete VD
Willie's Route S
... list all 8 climbs
Ticklists BETA
... not setup
Climbs Wishlist
... not setup


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One of the most important stories in the U.S. economy these days is the rise of extreme inequality.
Over the past 30 years, a larger and larger portion of America's income growth has gone to those in the top 10% of incomes, and especially those in the top 1%. This is a major change from the prior 60 years, in which the top 10% and the bottom 90% shared in the income gains.
A stark and startling example of this trend is the fact that, adjusted for inflation, "average hourly earnings" in this country have not increased in 50 years.
The Middle Class Is Broke: Pew Study Reveals Real Problem With Economy | Daily Ticker - Yahoo! Finance
Current Status: Published (4)
Seeded on Thu Dec 6, 2012 12:16 PM
keyboard shortcuts: V vote up article J next comment K previous comment


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Megachurch pastor Rick Warren remains as ill-informed on gay identity as ever. Unfazed by the notion that there may be a biological cause for homosexuality, Warren told Piers Morgan on CNN this week that acting on same-sex attractions is no different from "punching a guy in the nose" or consuming arsenic:
WARREN: Here's what we know about life. I have all kinds of natural feelings in my life and it doesn't necessarily mean that I should act on every feeling. Sometimes I get angry and I feel like punching a guy in the nose. It doesn't mean I act on it. Sometimes I feel attracted to women who are not my wife. I don't act on it. Just because I have a feeling doesn't make it right. Not everything natural is good for me. Arsenic is natural.
Rick Warren: Being Gay Is Like 'Punching A Guy In The Nose' Or Consuming Arsenic
Current Status: Blessed (1)
Seeded on Sun Dec 2, 2012 5:22 AM
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2 Recommendations
JustEliana's recommendation
A hair product that protects against hair straighteners, hair dryers and curling irons. Specifically made to protect against extremely high heat settings.
My Collections:
nikkig1's recommendation
Chi hair products are great. If you want quality then this is a great product for you. I will be adding more chi products to my collection. I don't no off any other hair spray that provides you with Thermal guard.


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Ok I decided on how to spend my first 1500 DSi points for Christmas:
Mario vs. Donkey Kong: Minis March Again (looks interesting and I really like custom level creators)
Paper Airplane Chase (Good time-waster)
Art Style: BOXLIFE (Looks like a good puzzle. Please don't try to convince me to switch this to PiCTOBiTS)
But I don't know what to do with the rest. Can anyone suggest a good 500 point game? I'm up for a casual or hardcore game as long as it isn't sudoku (I like it but I have the original full Brain Age) and it's 500 points
EDIT: I just remembered I'm going to get Trajectile, but I might get two points cards for Christmas (I did last year) and I'll probably use it on DSiWare so recommend any point games please
Edited on by Vander
go to www.virtualhamgames.com for great original independent games, a help service, and reviews for our games.
-a Virtual Ham Games fan


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Hippie Mandala Round Tapestry Beach Throw Yoga Mat Towel Indian Feather Roundie 50"
- Cotton
- Imported
- Fabric = cotton, color = Multi (This Is Not A Towel Fabric)
- size= 50 inch. Approx. CARE: Dry Cleaning Or Cold Water Wash
- EXCLUSIVE PRODUCT WITH BRAND PACKAGING. UNAUTHORIZED SELLERS WILL FACE INDEFINITE BAN. WE HAVE FEW AUTHORIZED RE SELLERS WHOM WE GIVE RIGHTS FOR SELLING ON AMAZON WITH PROPER BRAND PACKAGING. IF THE PRODUCT REACHES YOU WITHOUT THE PACKAGING REPORT TO AMAZON IMMEDIATELY WITH PICTURES OF THE PRODUCT MADE IN INDIA:-Beautifully Hand Crafted/Sketched By Local Artists. Please note that it is Hand Made Item.
- Made In India,This gorgeous piece of art can be used as Beach Throw, Towel Fabric, Yoga Mat
- Note:-This is to clarify this product is with the label of Brand name TRADITIONAL INDIA in the prime quality of cotton fabric .We are not liable for any of the seller selling a product with any other brand name. We have given authorization to limited seller which is under