text:
Having an unplanned encounter with the famous British actor, Nicole says she doesn't have the courage to greet and talk to him.
It was an unplanned encounter when "America's Next Top Model" cycle 13 winner Nicole Fox met Robert Pattinson for the very first time. Recounting the surprise run-in with the heartthrob, she tells E! News that it happened backstage at "Live with Regis and Kelly", where she made an appearance.
"I was backstage going to the bathroom - in a bathroom I probably wasn't supposed to be using," Nicole opens up. "But when I came out, [Pattinson] was in the hallway, like two feet away from me, [just] standing there. I was shaking." Asked if she approached the "Twilight" leading actor and talked to him, she answers "I didn't. He was surrounded by his throng of people. And so I didn't want to feel like a dorky fangirl. I just looked down at my shoes and walked away."
Nicole, furthermore, enthuses "I actually don't know that much about [Pattinson]. I haven't seen the 'Twilight' movies or anything like that. But I definitely have friends who are obsessed. For this Halloween, actually, I helped out one of my friends with her costume. She wanted a bigger-than-life portrait drawn of Robert Pattinson on her shirt. I drew that portrait - which is partially why I recognized him when I saw him in the hallway."
She goes on telling E! News, "I was like, Oh! That hair! I know that hair. I've drawn that hair!" adding "Perhaps I will begin to watch the Twilight movies now that I saw him in real life."


text:
Global profiling of genes modified by endoplasmic reticulum stress in pancreatic beta cells reveals the early degradation of insulin mRNAs
- First Online:
- Received:
- Accepted:
- Citations
- 868 Downloads
Pancreatic beta cells respond to endoplasmic reticulum (ER) stress by activating the unfolded protein response. If the stress is prolonged, or the adaptive response fails, apoptosis is triggered. We used a 'homemade' microarray specifically designed for the study of beta cell apoptosis (the APOCHIP) to uncover mechanisms regulating beta cell responses to ER stress.
Materials and methods
A time course viability and microarray analysis was performed in insulin-producing INS-1E cells exposed to the reversible ER stress inducer cyclopiazonic acid (CPA). Modification of selected genes was confirmed by real-time RT-PCR, and the observed inhibition of expression of the insulin-1 (Ins1) and insulin-2 (Ins2) genes was further characterised in primary beta cells exposed to a diverse range of agents that induce ER stress.
CPA-induced ER stress modified the expression of 183 genes at one or more of the time points studied. The expression of most of these genes returned to control levels after a 3 h recovery period following CPA removal, with all cells surviving. Two groups of genes were particularly affected by CPA, namely, those related to cellular responses to ER stress, which were mostly upregulated, and those related to differentiated beta cell functions, which were downregulated. Levels of Ins1 and Ins2 mRNAs were severely decreased in response to CPA treatment as a result of degradation, and there was a concomitant increase in the level of IRE1 activation.
In this study we provide the first global analysis of beta cell molecular responses to a severe ER stress, and identify the early degradation of mRNA transcripts of the insulin genes as an important component of this response.
KeywordsApoptosis CPA Cyclopiazonic acid Diabetes mellitus Endoplasmic reticulum stress Insulin Interleukin-1 Pancreatic beta cells
- aa-cRNA
aminoallyl antisense cRNA
activating transcription factor
immunoglobulin heavy chain binding protein
cyclopiazonic acid
C/EBP homologous protein
- eIF2α
eukaryotic translation initiation factor 2α
endoplasmic reticulum
ER-associated degradation pathway
- iNOS
inducible nitric oxide synthase
inositol-requiring ER-to-nucleus signal kinase 1
oxygen-regulated protein 150
proprotein convertase subtilisin/ kexin type 1/2
protein kinase RNA-dependent-like ER kinase
sarcoendoplasmic reticulum Ca2+-ATPase
unfolded protein response
X-box binding protein 1
Pancreatic beta cells function as nutrient sensors, responding to increases in circulating nutrients by synthesising and releasing insulin. During functional stimulation by glucose, insulin synthesis represents nearly 50% of the total protein biosynthesis by beta cells [1]. This places an enormous burden on the endoplasmic reticulum (ER), the organelle responsible for the synthesis and proper folding of secretory proteins [2], rendering beta cells vulnerable to agents that perturb ER function [3]. Disturbances in normal ER function lead to the accumulation of misfolded proteins and activate the unfolded protein response (UPR) [2]. The UPR is mediated through three ER membrane proteins, namely, protein kinase RNA-dependent-like ER kinase (PERK; also known as eukaryotic translation initiation factor 2-alpha kinase 3, EIF2AK3), activating transcription factor 6 (ATF6) and inositol-requiring ER-to-nucleus kinase 1 (IRE1; also known as ER to nucleus signalling 1, ERN1), the latter responsible for Xbp1 mRNA splicing and activation of the protein. The UPR decreases ER protein levels and restores ER function by (1) attenuating translation via activation of PERK and subsequent phosphorylation of the eukaryotic translation initiation factor 2α (eIF2α); (2) activating the transcription factors ATF6 and XBP1, which upregulate the expression of genes encoding ER chaperones and thus increase the folding capacity of the ER; and (3) degrading misfolded proteins via the ER-associated degradation pathway [4]. A fourth pathway has been recently described in Drosophila, namely, the degradation of mRNAs encoding ER-targeted proteins by IRE1, thus halting the production of new proteins in the organelle [5]. Failure of the UPR to solve ER stress leads to activation of the apoptosis pathway [6]. The mechanisms linking ER stress and apoptosis remain to be clarified, but may involve activation of the transcription factors C/EBP homologous protein (CHOP; also known as DNA-damage-inducible transcript 3, Ddit3) and ATF3 and the kinase JNK [4, 6, 7, 8, 9].
Homozygous mutations in the gene encoding PERK cause beta cell death and diabetes in Wolcott–Rallison syndrome in humans [10] and in a transgenic mouse model [11]. Even a partial reduction in eIF2α phosphorylation, when coupled with a high-fat diet, triggers beta cell failure and diabetes [12]. Prolonged inhibition of eIF2α dephosphorylation also triggers beta cell death [13], suggesting that an effective modulation of ER function is necessary for beta cell viability. In line with this, we and others have recently shown that NEFA and cytokines, agents that may contribute to beta cell death in type 2 and type 1 diabetes, respectively, cause beta cell apoptosis, at least in part, by triggering ER stress [13, 14, 15, 16, 17, 18]. Moreover, beta cells are particularly sensitive to agents that deplete ER Ca2+, such as the sarcoendoplasmic reticulum Ca2+-ATPase (SERCA) blockers cyclopiazonic acid (CPA) and thapsigargin [15, 18, 19]. We have recently shown that exposure of INS-1E cells to CPA for 6–12 h triggers severe ER stress, characterised by increased Chop, Bip (also known as heat-shock 70 kDa protein 5, Hspa5) and Xbp1 spliced mRNA expression and activation of a UPR-luciferase reporter construct [18].
Against this background, we have combined high-throughput and conventional experimental approaches to reveal the mechanisms regulating beta cell responses to ER stress. For this purpose, we used an 'in-house' spotted rat oligonucleotide microarray, the APOCHIP, containing 60-mer probes for nearly 600 genes selected for the study of beta cell apoptosis [20]. The APOCHIP provides reproducible data, and compares well with the Affymetrix GenChip [20]. Time-dependent profiles of the genes available in the APOCHIP were measured in INS-1E cells exposed to the reversible SERCA blocker CPA to create an ER stress compendium of several thousand measures. Elucidation of the global pattern of beta cell gene expression in response to ER stress involved statistical analysis of this large data set and confirmation by real-time RT-PCR of some genes. The results of this experiment indicated that ER stress causes an early and marked decrease in Ins1/2 mRNA expression, and this was independently tested in insulin-producing cells and primary beta cells exposed to CPA, thapsigargin or cytokines (IFN-γ+IL-1β).
Materials and methods
Cell culture and treatments
INS-1E cells were cultured in RPMI 1640 medium (Invitrogen, Paisley, Scotland) [21], while primary rat beta cells were FACS purified and cultured in Ham's F-10 medium (Invitrogen) [21]. Cells were plated and cultured for 48 h prior to the addition of test agents. The SERCA blockers—CPA and thapsigargin—were solubilised in DMSO and were used at concentrations of 25 μmol/l and 1 μmol/l, respectively. DMSO (0.125%) was used as the control condition in the experiments involving SERCA blockers. This concentration of DMSO does not affect gene expression or survival in INS-1E or primary beta cells ([15, 18]; data not shown). Recombinant rat IFN-γ (R&D Systems, Abingdon, UK) was used at a concentration of 0.036 μg/ml (±100 U/ml), and human recombinant IL-1β (a gift from C.W. Reinolds, National Cancer Institute, Bethesda, MD, USA) was used at a concentration of 10 U/ml for the INS-1E cell experiments and 50 U/ml for the primary beta cell experiments. The inducible NO synthase (iNOS) blocker NG-methyl-l-arginine (LMA; Sigma, Steinheim, Germany) was used at 1.0 mmol/l. CPA, thapsigargin, cytokines and LMA concentrations were selected based on our previous time course and dose–response studies [15, 18, 22].
Assessment of INS-1E cells viability
INS-1E cells were exposed to CPA or DMSO (control) for the time periods indicated. CPA was then removed by changing the medium, and the cells were subsequently incubated for a further 24 h before assessment of viability. For comparison, cells in some experiments were also treated with CPA for the last 9 and 12 h of the experiment. The percentage of viable, apoptotic and necrotic cells was determined as previously described [15, 18].
Preparation of the target for array analysis
INS-1E cells were exposed to CPA or DMSO (control) for 2, 6 or 12 h, or for 6 h followed by a 3 h recovery period in the absence of CPA. Cells were then collected, and total RNA was isolated using the RNeasy Mini Kit (Qiagen, Venlo, The Netherlands). Double-stranded cDNA was prepared and was used as template for aminoallyl antisense cRNA (aa-cRNA) synthesis [20]. The aa-cRNA was purified and coupled to a fluorophore, either indocarbocyanine (Cy3) or indodicarbocyanine (Cy5) (Amersham, Diegem, Belgium). The labelled aa-cRNA was fragmented, precipitated and resuspended in RNAse-free water for spectrometric quantification [20].
Hybridisation and data analysis
An aliquot (1 μg) of control target was mixed with 1 μg of CPA target labelled with the other fluorophore; all hybridisations were replicated with dyes swapped [20]. Microarrays were scanned with a GenePix 4000B scanner (Axon Instruments, Union City, CA, USA). Spot and surrounding local background intensities were quantified with GenePix Pro 5.0 (Axon Instruments) using the irregular spot feature. The gene expression log2-ratios were calculated from the spot intensities (with background intensity subtracted) and used for normalisation. Housekeeping gene-based Lowess normalisation of the microarray data was carried out using the tRMA package [23] written in R code (http://cran.r-project.org, last accessed in January 2007). The normalised log2-ratios of each dye swap were averaged. The means for the three independent experiments were then used for a Student's t test. To address the problem of multiple hypothesis testing, a method controlling for a false discovery rate (FDR) was applied [24, 25] using the Q-value package (http://faculty.washington.edu/~jstorey/qvalue/, last accessed in January 2007). Genes were considered as significantly modified by CPA if they had a q value equal or less than 0.06 (FDR of 6% among the significant genes) for at least one of the four time points studied.
Real-time RT-PCR, RNA stability and Ins1 promoter activity
For assessment of Ins1 promoter activity, INS-1E cells were transfected using lipofectamine (Invitrogen) with 250 ng of the rat Ins1 promoter-luciferase construct (a kind gift from G. Holz, New York University School of Medicine, New York, NY, USA) [28], and the pRL-CMV plasmid (50 ng; with Renilla luciferase used as an internal control for transfection efficiency). Twenty-four hours after transfection the cells were exposed to CPA or DMSO (control) for 6 or 12 h. Luciferase activities in the cell lysates were determined and expressed as firefly/Renilla (relative luciferase activity).
Statistical analysis
Data are shown as means±SEM, and comparisons between groups were made by the paired Student's t test or by ANOVA followed by the Student's t test with the Bonferroni correction, as indicated. A p value of ≤0.05 was considered statistically significant.
Viability of INS-1E cells exposed to a CPA-induced ER stress
In the presence of CPA, the percentage of apoptotic INS-1E cells had increased by the 4 h time point, and increased with time to study end, with 17% of cells apoptotic by the 12 h time point (Fig. 1). There was no significant increase in the proportion of necrotic cells (data not shown), confirming our previous observations that SERCA blockers kill beta cells by apoptosis [15, 18]. When beta cells were exposed to CPA for 9 h, and then washed and cultured for an additional 24 h without the SERCA blocker, the percentage of apoptotic cells was similar to that observed in beta cells exposed to CPA alone for 9 h (12.5 ± 1.3% vs 12.7 ± 1.2%, respectively; means±SEM, n = 4). Similar results were observed after exposure to CPA for 12 h, with or without a further 24 h incubation in medium alone (data not shown). This indicates that the effects of CPA are reversible, and suggests that beta cells trigger defence mechanisms that allow them to survive and recover once ER stress is removed. Based on these and previous experiments [18], we selected periods of 2, 6 and 12 h exposure to CPA for the subsequent array analysis. An additional group of cells exposed to CPA for 6 h, followed by a 3 h recovery period, was included to allow the identification of genes expressed in the early phase of ER stress recovery.
Identification of ER stress-modified genes by microarray analysis
Confirmation by real-time RT-PCR of CPA-induced modifications in mRNA expression of a selected set of changed genes from the microarray experiment
6 h
6 h
12 h
12 h
2.5 ± 0.2**
5.7 ± 0.9**
2.6 ± 0.2*
7.6 ± 0.6***
2.6 ± 0.3*
3.3 ± 0.5**
3.1 ± 0.3**
6.2 ± 1**
0.9 ± 0.02*
1 ± 0.1
0.8 ± 0.03*
0.9 ± 0.1
1.3 ± 0.08*
2.6 ± 0.4*
1.5 ± 0.1*
4.4 ± 0.4**
1.5 ± 0.3
2.8 ± 0.6*
2.1 ± 0.3*
4.9 ± 1.1*
1.3 ± 0.05*
3.6 ± 0.5**
1.6 ± 0.1**
4.1 ± 0.4**
Another group of genes modified by ER stress were those involved in beta cell differentiated functions (ESM Table 1). Thus, we observed a decrease in the expression of Ins2, Pcsk1, Pcsk2, Rab3a, Pdx-1, Isl-1, HNF-1α and HNF-3α. Inhibition was most marked for Ins2, the expression of which was decreased by 60–80% after 6–12 h (ESM Table 1). We also observed a 50% decrease in levels of Ins1 transcript after 6–12 h (data not shown); however, this gene failed to pass our statistical test.
ER stress induces a marked decrease in insulin mRNA expression in INS-1E cells and primary beta cells
In the present study we used the APOCHIP, a rat oligonucleotide microarray [20], to determine the molecular mechanisms regulating beta cell responses to ER stress. Two groups of genes were particularly sensitive to CPA: those involved in the response to ER stress, which were mostly upregulated, and those related to differentiated beta cell functions, which were mostly downregulated.
The genes encoding the ER chaperones Bip, calreticulin and Grp94, the ER stress-related transcription factors ATF4, ATF3 and Chop, the pro-apoptotic caspase 12 and the ER-protein translocator Sec61 were all upregulated by CPA, while the gene for cyclin D1 was inhibited during ER stress as a mechanism to prevent cell division [30]. Bip, Grp94 and calreticulin—three of the most abundant chaperones in the ER—are involved in the correct folding of nascent protein. They also carry out the following important functions in this organelle: (1) Bip and calreticulin are involved in the ER 'quality control' system, which leads to the destruction of malfolded proteins via the ER-associated degradation pathway (ERAD) via the proteasome [31, 32]; (2) Grp94 and calreticulin have a high calcium binding capacity, and are therefore involved in ER Ca2+ homeostasis [32, 33]; (3) Bip also plays a key role in the regulation of the three UPR transducer proteins ATF6, PERK and IRE1 via a binding-release mechanism [31]. Sec61 is involved in the formation of channels across the ER membrane, permitting the evacuation of malfolded protein from the ER lumen to proteasomes in the cytosol [34]. The transcription factor ATF4 regulates a set of protective genes related to amino acid import/metabolism and resistance to oxidative stress [35], and is also involved in the regulation of the pro-apoptotic protein Chop [36, 37]. ATF3, Chop and caspase 12 are three potential mediators of ER stress-triggered beta cell apoptosis, as suggested by (1) partial protection against cell death in Chop knockout islets exposed to NO [8] and in ATF3-deficient islets exposed to IFN-γ plus IL-1β [7]; (2) Delayed diabetes onset in Akita mice with an homozygous deletion of Chop [9]; (3) decreased expression of Bcl2 in Chop-overexpressing cells [38], an effect suggested in the present study by the inverse relationship between Chop and Bcl2 expression (ESM Table 1) (4) resistance of renal tubular epithelium and neurons from caspase 12 null mutant mice to ER stress-induced apoptosis [39]; (5) diabetic phenotype secondary to beta cell loss in mice overexpressing ATF3 [7].
In the present study, expression of ATF3 and Chop returned to basal levels after the 3 h recovery period, while expression of the Bip and Grp94 remained elevated. This pattern of gene expression may explain how beta cells endure 9–12 h of severe ER stress without reaching the 'point of no return' for cell death; indeed, as soon as CPA was removed, the induction of apoptosis was arrested in the surviving cells.
CPA induced a marked decrease in the expression of several genes involved in the maintenance of a beta cell differentiated phenotype. There was a decrease in the expression of Ins2, Pcsk1/2 (whose protein products, the prohormone convertases 1 and 2, are responsible for the conversion of proinsulin to insulin [40]), Rab3a (which encodes Ras-related small GTP binding protein 3A, involved in insulin exocytosis [41]) and Pdx-1, Isl-1, HNF-1α and HNF-3α (which encode transcription factors involved in the maintenance of a differentiated beta cell phenotype [42]). Beta cell exposure to the cytokines IFN-γ and IL-1β, which induce ER stress [15], results in the inhibition of expression of Pcsk1/2, impairing the conversion of pro-insulin into insulin [43, 44], and the decreased expression of Pdx-1 and Isl-1 [26]. These cytokines also decrease the expression of SNAP-25, VAMP-2 and Rab3a, whose protein products are involved in granule fusion with the beta cell membrane [22, 45], preferentially decreasing the first phase of exocytosis [45]. The present data suggest that these effects of cytokines are, at least in part, secondary to ER stress.
The most marked effect of CPA was the decrease in the expression of Ins1 and Ins2 mRNAs. Similar findings were observed in INS-1E cells exposed to thapsigargin or cytokines (IFN-γ plus IL-1β) and in primary beta cells exposed to the same agents. Cytokines inhibit Ins1/2 mRNA expression and pro-insulin biosynthesis in rat and mouse islets [46, 47, 48]. The decrease in Ins1/2 levels is secondary to NO production [22], a finding confirmed in the present study. Cytokine-induced ER stress is prevented by iNOS blockers [15], suggesting that the inhibitory effects of cytokines on Ins1/2 mRNA expression are, at least partly, secondary to ER stress.
It has been recently shown that ER stress causes the rapid degradation of mRNAs targeted for translation at the ER in Drosophila cells. This degradation is mediated by IRE1 activation, and complements other UPR mechanisms by selectively halting the production of non-vital proteins at the ER [5]. The two insulin gene transcripts are the most abundant mRNAs directed to the ER of rat beta cells, and a rapid decrease in Ins1/2 mRNA expression could represent a novel mechanism of beta cell adaptation to ER stress. Against this background, we evaluated whether CPA-induced ER stress activates the IRE1 pathway in INS-1E cells, as measured by Xbp1 splicing, and whether the observed decrease in Ins1/2 mRNA is due to mRNA degradation. Our results indicated that this was indeed the case. Thus, CPA induced early and intense Xbp1 splicing, which was paralleled by the early degradation of both Ins1 and Ins2 without affecting the activity of the Ins1 promoter.
Acute 'physiological' and prolonged 'pathological' exposure to high glucose triggers several markers of the UPR; however, while short-term (1–3 h) exposure to high glucose favours insulin biosynthesis, long-term (3–7 days) exposure decreases Ins1/2 mRNA expression [49]. Phosphorylation of IRE1α is observed under both conditions, but Xbp1 splicing is only detectable after a long term exposure to high glucose [49]. Xbp1 splicing therefore seems to be a marker that differentiates between 'physiological' and 'pathological' activation of the UPR. In this study, CPA exposure clearly induced Xbp1 splicing (Fig. 6). In addition, we have recently completed another study on the regulation of Chop mRNA expression by diverse ER stresses in insulin-producing cells [37], where the effects of CPA, at the concentration used in the present study, induced ER stress similar to that induced by cytokines and by the NEFA palmitate. Moreover, it was recently described that ER stress markers are present in islets obtained from diabetic db/db mice and patients with type 2 diabetes [50]. These observations suggest that the present data reflects a 'pathological' beta cell situation of potential relevance to the diabetic state.
The present study reports the first global analysis of beta cell molecular responses to severe ER stress, and identifies the early degradation of Ins1 and Ins2 mRNAs as an important component of this response. We suggest that massive degradation of Ins1/2 mRNA, the most prevalent ER-targeted mRNA in beta cells, alleviates functional demand on the ER. This, together with a vigorous upregulation of ER chaperones, contributes to beta cell survival and recovery once the source of ER stress is removed.
This work was supported by grants from the European Union (STREP SAVEBETA, contract no. 036903 in the Framework Programme 6 of the European Community), the Fonds National de la Recherche Scientifique (FNRS; National Fund for Scientific Research; Belgium) and the 'Communauté française de Belgique-Actions de Recherche Concertées' (ARC; French Community of Belgium-Concerted Research Actions) to D. L. Eizirik, and a JDRF Transition Award Grant to A. K. Cardozo. We gratefully acknowledge G. Høj for advice on the microarray procedure and G. Pirot for developing the handmade tools to dry the arrays. We also thank M. A. Neef, G. Vandenbroeck and R. Leeman for excellent technical support. This paper is dedicated to the memory of Professor Claes Hellerström, who made many crucial contributions to our understanding of pancreatic beta cell function and dysfunction.
Duality of interest
The authors declare that they have no duality of interest in connection with this study.

subset: commoncrawl


text:
This is so cheerful!
simple and beautiful !
With the way the art style it, it almost reminds me of the guy who did "Howells Moving Castle" or "Spirited Away". ^_^
It looks like a hand done painting on canvas! I love your brush techniques! Very, very, pretty!
Why are you so good? <3 And why this deviantian doesn't have any comments? D: This is really awesome... colours, atmosphere, everything. : )


text:
Life is
full of a million moments when we are reminded that
delight is not a word... Moments that have inspired us
to build a world for you,and around these delightful
experiences and make it our life's work to deliver them.
Day in and day out through, action, thought, word,
intent. In every transaction that we conduct. In every
relationship that we build. So that it becomes a way of
life. And everything about us becomes
Bangalore Office
Goel Ganga Realty Pvt. Ltd.
Ganga Chelston, Silver Spring Road, Behind Bageecha
Restaurant, Kundanhalli Gate, Marathalli, Bangalore
Phone No. : 080 41269486 / 41482153
Member of Credai Pune (PBAP) | (c) All Rights Reserved
By Goel Ganga Group | Site Designed By


text:
Number of items: 2.
Bonarini, A. and Bonacina, C. and Matteucci, M.
An approach to the design of reinforcement functions in real world, agent-based applications.
IEEE Transactions on Systems, Man, and Cybernetics - Part B, 31 (3).
pp. 288-301.
Bonarini, A. and Invernizzi, G. and Labella, T.H. and Matteucci, M.
An architecture to coordinate fuzzy behaviors to control an autonomous robot.
Fuzzy sets and systems, 134 (1).
pp. 101-115.
This list was generated on Mon Sep 10 16:52:03 BST 2007.


text:
by Staff Writers
London, UK (SPX) May 09, 2014
"What a curious feeling," says Alice in Lewis Carroll's tale, as she shrinks to a fraction of her size, and everything around her suddenly looks totally unfamiliar. Scientists too have to get used to these curious feelings when they examine matter on tiny scales and at low temperatures: all the behaviour we are used to seeing around us is turned on its head.
In research published today in the journal Nature Communications, UCL scientists have made a startling discovery about a familiar physical effect in this unfamiliar setting.
Phase transitions are a category of physical phenomena in which the properties of a sample and the relationships between the particles that make it up suddenly change. Phase transitions include familiar events such as water turning to ice when temperature drops, or a magnet losing its magnetisation when temperature rises.
On human scales, and at ambient temperatures, phase transitions are well understood. They are linked to the temperature (and hence the vibration, orientation and movement of particles) of an object. In quantum physics, however, phase transitions behave slightly differently, and can even occur close to absolute zero, when virtually no heat is present in a sample.
These occur when a factor which affects the whole sample, such as a magnetic field, is changed. But in certain cases, quantum phase transitions can also happen when varying a highly localised factor, such as changing the coupling between a single pair of particles on the edge of such a system. These are called boundary phase transitions and would be like melting an entire iceberg by touching a corner of it with a hot poker.
Dr Abolfazl Bayat and Professor Sougato Bose (both UCL Physics and Astronomy), along with colleagues at other institutions, have probed the nature of boundary phase transitions in quantum systems. For the first time they have identified a measurable quantity that can label the distinct phases of such a system.
"When phase transitions happen, scientists often talk of an 'order parameter'," says Bayat. "This is the value which suddenly changes, such as the orientation of magnetisation in a metal, or the spacing of atoms in a sample which determines whether it is liquid or solid. Getting a handle on order parameters in quantum boundary phase transitions is much harder, but we have identified one in this research."
Bayat and Bose studied a system in which a tiny change applied to a single pair of impurities causes a change in the entire system. The two impurities can either be entangled with each other, or can separately be entangled with the left and right hand parts of the system. Changing the pairing of the impurities acts like a switch on the whole system, triggering a phase transition in the form of a sudden change in the entire sample. "We found that that a quantity called the Schmidt gap has all the features of an order parameter for this phase transition," says Bose. "That means that mathematically it characterizes all the features of the phase transition in an analogous way to how magnetisation does for a magnet".
However, unlike magnetisation, which can be easily measured, the Schmidt gap is a non-localised quantity which requires every particle in a system to be individually measured. Although, this a challenging task, it is becoming viable in recent experiments in ultra-cold atoms.
This research opens up new possibilities for exploring phase transitions in quantum physics. In particular, where conventional methods which use localised order parameters are not applicable, this gives a new means of studying phase transitions. It may help to determine new phases of matter and shed light into the structure of complex systems.
An order parameter for impurity systems at quantum criticality is published in Nature Communications on 7 May 2014.
Related Links
University College London
Beyond the Ice Age
|The content herein, unless otherwise known to be public domain, are Copyright 1995-2014 - Space Media Network. All websites are published in Australia and are solely subject to Australian law and governed by Fair Use principals for news reporting and research purposes. AFP, UPI and IANS news wire stories are copyright Agence France-Presse, United Press International and Indo-Asia News Service. ESA news reports are copyright European Space Agency. All NASA sourced material is public domain. Additional copyrights may apply in whole or part to other bona fide parties. Advertising does not imply endorsement, agreement or approval of any opinions, statements or information provided by Space Media Network on any Web page published or hosted by Space Media Network. Privacy Statement All images and articles appearing on Space Media Network have been edited or digitally altered in some way. Any requests to remove copyright material will be acted upon in a timely and appropriate manner. Any attempt to extort money from Space Media Network will be ignored and reported to Australian Law Enforcement Agencies as a potential case of financial fraud involving the use of a telephonic carriage device or postal service.


text:
The Chinook vibrated with deeper and deeper groans until its twin engines managed to heave up our dead weight.
We get in line, and on the count of three, we heave a log onto our shoulders.
Silently you assume positions of leadership, oh so subtly giving slackers the heave ho.
But Lomax can heave a small sigh of relief, at least for now: Legislative reform to the 1033 program will not happen in 2014.
They made me anchor in the outer roads and told me to heave out my dead.
The basket danced inquiringly, tipped, and began to heave upward.
We pull still further out in the wake of the ship, and heave up again; something ripples here abeam of us.
"heave, and I'll hoist up the bag," suggested Mayo at the rail.
Cochrane, at the moment, felt an impulse to heave him out an airlock as a probable danger.
Old Gordon was startled and he tried to heave up out of his chair.
Old English hebban "to lift, raise; lift up, exalt" (class VI strong verb; past tense hof, past participle hafen), from Proto-Germanic *hafjan (cf. Old Norse hefja, Dutch heffen, German heben, Gothic hafjan "to lift, raise"), from PIE *kap-yo-, from root *kap- "to grasp" (see capable).
Related to Old English habban "to hold, possess." Intransitive use by c.1200. Meaning "to throw" is from 1590s. Sense of "retch, make an effort to vomit" is first attested c.1600. Related: Heaved; heaving. Nautical heave-ho was a chant in lifting (c.1300, hevelow).
1570s, from heave (v.).
A shelter: Heave. Any shelter used by a policeman to avoid the elements (1950s+ Police)
To vomit; barf (1868+)


text:
Green Strapless Georgette Dresses by Nicole Miller
This is such a cute dress for St. Patrick's Day!
A women's green t-shirt that says "Irish today, hungover tomorrow." How clever.Added 9 Years Ago from Amazon.com
A green t-shirt with a large distressed shamrock on the front.Tags: t-shirts, Clothes, fashion, style, green, shamrocks, St. Patrick's Day, distressedAdded 9 Years Ago from Amazon.com
This shirt is true for the majority of people who celebrate St. Patrick's Day.Added 9 Years Ago from Amazon.com
Bright green Converse sneakers. There is no reason NOT to buy them in green!
Green Ralph Lauren sunglasses. Hopefully there is sun for St. Patrick's Day!Tags: Ralph Lauren, polos, fashion, sunglasses, accessories, style, green, St. Patrick's Day, ralph sunglassesAdded 9 Years Ago from Kitson
An Alice and Olivia knit dress. It has a tie around the waist and ombre stripes throughout.Tags: Clothes, fashion, style, dresses, green, St. Patrick's Day, Alice and Olivia, ombreAdded 9 Years Ago from ShopBop
Neon green bell bottom pants. I think I would wear these all the time, not just on St. Patrick's Day.
Alice and Olivia green twill cuff shorts. St. Patrick's Day is a perfect excuse to buy green shorts!Tags: fashion, style, green, cuffs, twill, shorts, St. Patrick's Day, Alice and Olivia, ClothesAdded 9 Years Ago from ShopBop
A forest green leather bomber jacket. Has a zipper closure and extra zippers on the sides for decoration.
A green oversized Chloe cardigan sweater. Has two front pockets and buttons down the front.
A green camisole that is reversible. A great way to show your St. Patrick's Day spirit.Tags: vintage, Clothes, fashion, style, green, camisoles, reversible, St. Patrick's Day, tank topsAdded 9 Years Ago from ShopBop
Green So Low pants that say Peace on the fold. They are comfortable and stretchy (good for drinking activities).
Each earring has two four leaf clovers on it. They are made of 18K gold and have diamonds in each leaf.
14K gold clover earrings with a clear rhinestone detail.Added 9 Years Ago from Neiman Marcus Online
A basic green t-shirt that says "love and luck" on the front in white.
A gray Hello Kitty t-shirt that has Hello Kitty in green and says "Don't Pinch Me.Tags: fashion, Clothes, style, t-shirts, hello kitty, tees, St. Patrick's DayAdded 9 Years Ago from Wet Seal
A bright green t-shirt that says "This is my lucky shirt." Perfect for St. Patrick's Day and I guess for days you need luck in general.
I'll definitely fake it for some corned beef, cabbage and potatoes!Tags: t-shirts, Clothes, fashion, irish, style, white, funny shirts, Womens Tees, St. Patrick's DayAdded 9 Years Ago from Forever 21
Classic Chuck Taylor inspired emerald green high tops. Beautiful and bold color.
I'm in love with this style of blouse by Robert Rodriguez ruffled blouse. he hue of this green is amazing, almost an emerald, a deep emerald. Make the best of this trend seen at mb fashion week and pair with a pair or Robert rodri... I'm in love with this style of blouse by Robert Rodriguez ruffled blouse. he hue of this green is amazing, almost an emerald, a deep emerald. Make the best of this trend seen at mb fashion week and pair with a pair or Robert rodriguez super wide leg trouser pants. This top has a ruffled collar and front, a tie waist and gathered in the back. You can't lose in this fab top.


text:
Rent Textiles and Apparel in the Global Economy 3rd edition today, or search our site for other textbooks by Kitty G. Dickerson. Every textbook comes with a 21-day "Any Reason" guarantee. Published by Prentice Hall.
Need help ASAP? We have you covered with 24/7 instant online tutoring. Connect with one of our tutors now.


text:
It is one of the largest underground substations ever attempted in the
It is PECO Energyís first and largest underground substation.
It is the only PECO substation which is contained entirely underground.
Completed in 1966, Mall Substation took several years to plan and more
than one year to construct.
The floor of Mall Substation is 30 feet below ground level.
order to allow plants life to flourish above it, the roof of Mall Substation
is 8 feet below ground level.
substation is a big, concrete box, 75 feet wide by 225 feet long, with
21 foot ceilings and 18-inch thick walls. Because it is below the water
line, the entire structure is encased in a waterproof membrane made of
four-ply felt and bitumen (tar-like substance.)
The small, aboveground entrances (for personnel and equipment) were screened
with red brick walls to blend with the colonial effect of the surrounding
The substation became necessary when construction of the Federal Court
and Office Buildings at 6th and Market Streets meant the demolition of
PECOís three-story Franklin Substation.
order to complete Mall Substation, PECO developed three highly reliable
duct seals which have since been adopted as an industry standard design
for positive pressure seals.
Mall Substation
is totally automatic and requires only periodic check-ins.
Mall Substation currently feeds electricity to 1,587 major Center City
business customers.
Mall Substation was constructed in two sections separated by a concrete
wall. The idea is to insure that one of the two sections continues to
operate in the event of a major malfunction in the other.
Peco Energy


text:
» Show All «Prev «1 ... 2281 2282 2283 2284 2285 2286 2287 2288 2289 ... 5022» Next»
Jacobs, Edward
Ref: KBp123
Status: Located
Balls Pond Road Jewish Cemetery (Kingsbury Rd), London, 1. England, UK
Notes: Balls Pond Jewish Cemetery: Opened in 1840/3 and closed in 1951. Owned by West London Synagogue Described as being neatly kept and full of very large tombstones by Mrs Basil Holmes in London Burial Grounds 1896, Fisher-Unwin.
For further information on burials at Balls Pond go to http://www.apex.net.au/~tmj/balls-pond/
General views of the cemetery can be found here
Status: Headstone photos - COMPLETE
If you have any photos you would like to donate to the Cemetery Scribes please Contact Us THANK YOU!!


text:
Go to Toro
Toro Super Recycler
Spark Plug Conditions
Spark Plug Conditions
Printer-Friendly Version
Page 45
If your spark plug shows any of the conditions besides Normal, the spark plug must be replaced.
Replacing a Spark Plug
See your Owner's Manual for the correct spark plug for your specific model. .
Disconnect the spark plug wire from the spark plug.
Remove the spark plug with a spark plug wrench.
When installing the new spark plug, ensure the spark plug has the proper air gap spacing. Measure the spark plug's air gap with a gap tool.
Gapping a Spark Plug
copyright 2004 OneCARE, Inc.
Reinstalling the Spark Plug
: Install the spark plug with a 13/16" spark plug socket and ratchet wrench (tighten it to 180 inch pounds torque). If you do not have a torque wrench, tighten firmly. Consult your Owner's Manual for your specific spark plug's socket size.
On the Web


text:
Roguelike puzzler Road Not Taken launches on PlayStation 4 on 6th August 2014, developer Spry Fox has announced.
A Vita version launches later this autumn, Spry Fox boss David Edery wrote on the PlayStation blog.
In Road Not Taken you play a magical ranger who must save lost children in a forest comprised of a series of single-screen puzzles.
Each screen's exit is blocked and you have to sort out what to do to unlock it. Given that you're a magic wizard, you can levitate any object and toss it around.
However, every action you take depletes your stamina, and when that's all gone it's game over. No restarts. No continues.


text:
November 15 2008
Nicholas Brendon to return to Criminal Minds. On the November 19th episode, Nick will be reprising his role as Kevin Lynch.
You need to log in to be able to post comments.
About membership.
This site will work and look better in a browser that supports web standards, but it is accessible to any browser or Internet device.


text:
Could Donald Trump Be the Next Governor of NY?
Donald Trump for governor?
The New York Post is reporting that GOP bigwigs in the Empire State want the Donald to run against Gov. Andrew Cuomo in next year's New York state election.
Via the New York Post:
"So far, Trump, who only recently learned of the effort, which is backed by state GOP Chairman Ed Cox and other party leaders, hasn't said a flat "no.'' Asked for comment by The Post, Trump left open the possibility of entering the race and blasted Cuomo, and even Cuomo's dad, ex-Gov. Mario Cuomo, for their records in office."
The Post's article was apparently the first Trump heard of the GOP's desire to get him to mount an election campaign. The effort is being backed by state GOP Chairman Ed Cox and other party leaders.
Photo Credit: Getty Images


text:
If you intend to purchase a private jet plane either for business or pleasure, it is importaan airport nt to consider some factors before you spend your hard-earned money on it. There are a myriad of brand new and used private jets available in the market, and the amount that you should pay for one all depends on the features and size of the jet. Before you decide to buy one, make sure that you know and you have thought about what you really want. Think about the number of passengers or the an airport you will travel most of the time. In that way, you will have an idea on what you should have. You can ask some people who are knowledgeable about private jet, or you can also look around in the internet to know the average prices of the jet planes that you are looking for.
Private Jets can cost about five million dollar just for the standard size plane. To charter a jet can be about five thousand dollars a trip. This can be expensive especially if you have to go out a hire a pilot with great experience. Private Jets are use a lot of gas and you can spend ten thousand dollars on a complete tank refueling. As with any form of transportation, private jets have a huge risk when going to an airport. The Jet will have to pass the FAA test, just an inspection on a vehicle. Owners have to be careful to not overload the place with baggage which can weigh the plan down. Just to make sure things are right every owner should read over the rules and regulations.
In this day and age of heightened security at all the airports of the world, chartering a private jet can be not only a delightful way to travel, but it can be convenient and less expensive. No longer just in the realm of the rich and famous, private jet charters are being utilized, more and more by large businesses and corporations to, not only, avoid wasted time in airports, but to meet tight schedules in a fast world and conduct business in route. Time is money. Private air charters can be seen in all the major airports in an airport and there are planes to meet all needs. With speeds in excess of 300 miles per hour and ranges approaching 6000 miles, there are charter jets that can accommodate anywhere from four to over 60 passengers. Private jets offer luxury, comfort, impeccable service and are well equipped with business in mind.
More and more businesses are buying part ownership of a jet. It is almost like buying into a time share program. They own up to one fourth of the plane. They are allotted a certain amount of hours to use the plane. They help pay for expenses and keeping up on the plane. It is the perfect solution for many businesses and corporations who have employees who need to travel to an airport. It can be convenient and cost conscious all at the same time. These planes can be bare bones or luxury planes. It will depend on the needs of the clients. Many times they are converted commercial planes. At one time they were used by a commercial airline, but have been sold to be used privately. For the business who could benefit from this type of service, it is certainly an excellent option. Private jets are the best way for business people to get to their destination on time and stress free.
سكس مقاطع للسكس, سكس فديوه, سكس_شرموطه, صورازباب كبيره كامله, تنقل الحيوانات اسباب, سكس وكس فرنسى, أكبر زب في العلم, صورةزب ظخم, افضل نيك بالعالم, صناعه كوس, نيك الذب فيديو, البنت التى لها زبر مثل الرجال, سكس مبشر, شي سكس, نياكةزب داخل كس , موسيقى اللي في المطار, طيران محج قلعة, المسافر للخارج والذ متعه لنيك, طيارات الي سالزبورغ, شيمبو, أرقام الطرق في ولاية أركنسو, صور مطار دالاس بولايه تكساس, فورت براج, مطار دالاس التنفيذي, الطائرة الخفيفة, كم عدد مقاعد falcon 900b, جزيرة بانجاسينان, فيرفيلد, افضل الطائرات التجارية الصغيرة, carbondale ولاية


text:
In 1963, the Board of Trustees of the Amon Carter Museum of Western Art in Fort Worth, Texas invited the University of Texas at Austin School of Architecture to participate in a survey of nineteenth century historic buildings in Texas. The Amon Carter Museum (ACM) had recently opened in 1961 and planned to use the photographic documentation from the survey as part of its exhibition development program. The survey would be uniquely focused on Texas, modeled on previous national efforts such as the Historic American Building Survey (HABS) operated by the National Park Service. The Texas Architecture Survey (TAS) would document nineteenth-century buildings, including those at risk of demolition or being condemned.
John Garner began work as Field Director of operations on January 27, 1964. Garner was a Master's student in the University of Texas School of Architecture, working with Professors Martin Kermacy and Blake Alexander. Garner drove throughout Texas, establishing local contacts and documenting buildings with 35 mm slide transparency film. These slides, and his field notes (called "Building Description Lists") [both found in Series B], were reviewed by the university steering committee. The committee and ACM then created building lists for professional photographer Todd Webb to shoot in large format film.
The TAS designated eight geographical districts within the state of Texas. Field Director Garner worked by district, recording notes about visited counties, cities, communities, and buildings. Garner (and collaborators) used a classification system based on abbreviations for these districts, counties, and cities to identify and organize the slides. Each building within a city was given a sequential number. Garner worked in District One first, mostly in Spring 1964.
Although it appears that the TAS planned to visit all 254 counties and eight districts in Texas, their
efforts actually focused on central and eastern Texas. Garner completed his fieldwork and resigned as Field
Director on June 1, 1965, thus concluding all primary data acquisition for the TAS. In his final report,
dated June 24, 1965, Garner noted that
Todd Webb, commissioned by the Amon Carter Museum as a professional photographer, worked from a prescribed
building list developed by the Texas Architecture Survey. Although Field Director Garner did not work in
West Texas, Todd Webb was able to photograph several buildings in the region. His photographic coverage
often followed Garner's preliminary work but does not mirror it. No documentation exists to establish the
terms or period of employment for Todd Webb, but his shot logs date from
All materials accrued by the field investigation were deposited [as of 1965] either in Fort Worth or Austin by Field Director Garner upon termination of his duties. Principally, all record photographs were left in the security of Professor Alexander at the University of Texas, while all equipment and supplies were returned to the Carter Museum. Todd Webb continued working throughout 1966.
The TAS also relied on external collections of historical photographs to aid the selection of outstanding buildings for the survey and publications. The Amon Carter printed negatives produced by architect and historian David Williams. The TAS also acquired the Gus Cranz collection of historic Texas architecture from his widow and son. Records also include what was internally termed by the TAS as the "Texas Frontier Architecture File."
Todd Webb's work was intended for gallery exhibition at the ACM and publication in two architectural history books. The TAS collection contains all of his shot logs, contact sheets, contact and study prints, negatives, and a selection of large prints. The descriptive information is not standardized, although many photographs are identified by building name, street address, general location, city, county, previous resident, or other data.
Todd Webb did not use the same classification filing system for his photographs as Garner. The Webb photographic negatives are arranged by Amon Carter Museum (ACM) accession numbers.
Two books resulted from the TAS project, which are illustrated exclusively with Todd Webb photographs:
In 1969, the Amon Carter transferred the bulk of the TAS collection to the University of Texas. Professor Blake Alexander may have retained some items as well. The "Texas Frontier Architecture File" records were donated by Garner in 1986, followed by another gift of large exhibit panels from the Amon Carter in 1987. The large exhibition panels are not considered part of the collection. In 2002, the Amon Carter transferred several boxes of material including the Gus Cranz and David Williams reference collections, and Todd Webb photographic material. In 2004, the Visual Resources Collection donated the field slides (35 mm) taken by Garner.
Todd Webb (1905-2000) was an American photographer who befriended Alfred Stieglitz and Georgia O'Keeffe, with works held by over 15 museums, including the Museum of Modern Art, NY; the Metropolitan Museum of Art, NY; the Chicago Art Institute, IL; and the George Eastman House, Rochester, NY. Referred to as "an historian with a camera," Webb was an established photographer when commissioned by the Amon Carter Museum to produce photographic works for the Texas Architecture Survey. Webb was already working with the Carter to exhibit a solo show,
Todd Webb had two successful exhibitions at the Amon Carter featuring his work with the TAS:
The collection includes the administrative records of the Texas Architecture Survey (1963-1966). The strengths of this collection are (1) the documentary "building description lists" containing information on individual buildings and (2) photographic documentation of nineteenth century buildings in Texas as they appeared circa 1964 and 1965. Building description lists may include field notes about building dates of construction, names of former owners, and notes on architectural details of public buildings, private homes, and other structures. The Texas Architecture Survey (TAS) created two sets of images for its own mission. Field Director John Garner took 35 mm slide transparencies for reference and review, while Todd Webb produced professional, documentary photographs using 120 mm or larger film negatives. The UT School of Architecture purchased Garner's original set of slides, which are now part of the Texas Architecture Survey records. Todd Webb's photographic documentation includes negatives, contact sheets, contact prints and large prints, indexes to buildings photographed, and shot logs. The TAS relied on reference collections of prints and negatives acquired by Professor Alexander, Gus Cranz, David Williams and other photographers. These reference materials guided location scouting and survey selection.
Materials are arranged into six series, based on creator.
Where possible, items are arranged chronologically by date or trip survey sequence. Series A is
arranged without original order, and priority has been given to comprehensive or informative summary
reports. Slides are arranged alphabetically by county, then city. Todd Webb negatives are arranged by item
number and size format. Photographic prints are arranged alphabetically by county or city when possible.
Please refer to additional arrangement notes throughout this finding aid.
Related materials providing additional documentation for the work of the Texas Architecture Survey can be found both at the University of Texas at Austin and at the Amon Carter Museum in Fort Worth, Texas.
Collections at the Alexander Architectural Archives:
Drury Blakeley Alexander: An Inventory of his Drawings, Papers, and Photographic Material, [1887]-1995
David Reichard Williams: An Inventory of his Photographs, Negatives, and Records, 1916-1978
Records at the Harry Ransom Humanities Research Center at the University of Texas include Todd Webb photographic prints, and originals of John Garner's Building Description Lists and Field Reports. Texas Architecture Collection (Discrete Collection 136.01-136.35)
Collections at the Amon Carter Museum of Fort Worth, Texas:
Institutional Records, contact archival staff.
This collection is open for research. Researchers must register and agree to copyright and privacy laws before using archival materials. As all or portions of this collection may be housed off-site, advance notice of at least three working days is required for retrieval. Certain items may require additional time for flattening or humidifying before they can be viewed. Access is by appointment only. Please contact the archives' reference staff for further information.
Manuscript collections and archival records may contain materials with sensitive or confidential information that is protected under federal or state right to privacy laws and regulations. Researchers are advised that the disclosure of certain information pertaining to identifiable living individuals without the consent of those individuals may have legal ramifications (e.g., a cause of action under common law for invasions of privacy may arise if facts concerning an individual's private life are published that would be deemed highly offensive to a reasonable person).
The Alexander Architectural Archives operate in accordance with applicable federal or state laws and regulations, providing unrestricted access to university records not covered by state and federal right to privacy acts.
The Alexander Architectural Archives, The University of Texas Libraries, and The University of Texas at Austin, assume no responsibility for infringement of literary property rights and copyright or for liability to any person for defamation or invasion of privacy that results from a researcher's use of collections.
Researchers agree to indemnify and hold harmless The University of Texas at Austin, and their officers, employees, and agents from and against all suits, claims, actions, and expenses arising out of use of collections held by the libraries. Please alert staff if anything inappropriate is found during research.
Copyright interests in this collection may not have been transferred to the University of Texas. Researchers assume full responsibility for observing all copyright, property, and libel laws as they apply. Additionally, the public use of material must be cited. See citation information below.
Texas Architecture Survey records, Alexander Architectural Archives, University of Texas Libraries, The University of Texas at Austin
Processing completed by Alexandra Myers and Donna Coates in
The Texas Architecture Survey (TAS) was active from 1963-1966, followed by a period of record management of Todd Webb prints (and negatives) by the Amon Carter Museum until 2002. John Garner served as Field Director of the Survey from January 1964 until June 1965, working across Texas to document historical building facts and acquire preliminary reference imagery. TAS administrative documents include field reports, correspondence, academic reports, and a card index of regional personal contacts. Administrative documents from the Amon Carter Museum detail operating budgets and indices of Todd Webb photographic negatives, prints, and images as published in the two resulting architecture books. These indices are excellent resources for locating photographs within a Texas city.
Series A is arranged without original order, and priority has been given to comprehensive or informative summary reports.
The following documents were produced during the administration and management of the Texas
Architecture Survey from
Note: Progress Report #1 contains a map of the Texas counties and districts
In 2002, the Amon Carter Museum of Fort Worth, Texas de-accessioned all remaining items from the Texas Architecture Survey, including their own administrative records detailing catalog indices and accession records for Todd Webb photographic images and negatives. The accession record numbers assigned by the Amon Carter Museum cover all Todd Webb negatives, and begin with P1977.12.1 for his first frame. An administrative binder maintained by the Museum was disassembled and items were sequentially rehoused into archival folders 2-12 through 2-18. The binder was entitled "Index to the Texas Architecture Survey Negatives by Todd Webb 1966." The indices to Todd Webb photographs are a useful resource for locating information about buildings in a specific town. It is also advised to use the indices in conjunction with the two published books, as the indices include detailed references to page numbers and image plate numbers.
As Field Director, Garner created 35 mm slides and paper documentation of historical buildings to supplement additional slides created by Professor Alexander and others. All slides were reviewed by the Texas Architecture Survey and were later re-used in architecture lectures. Slides are hand-labeled with the county-city-building number abbreviation system used by Garner and the TAS. Descriptive labels were added later by Visual Resource Collection staff in the School of Architecture, following the bulk purchase of the original slide collection. Slides are stored in metal cabinets and are arranged alphabetically by Texas county. Within each county, slides are grouped by city. There are also a few slides from Mexico. Slides can be examined against information in the building description lists, although there is not perfect accordance between the two.
In his "student research report to Professor Kermacy" (1964) Garner states,
After being transferred to the School of Architecture in the late 1970's, the slides were duplicated on request. Red marks indicate slides duplicated for Professor Blake Alexander, yellow marks indicate duplicates for lecture series, and dark blue represents special requests by faculty. There is also a separate set of slides, with 271 duplicates made for the Amon Carter Museum.
The electronic index to the TAS slides details known information for each slide, with descriptions indentifying the District, County, City, Building, Street Address, Date of Building, Item Count, View (Exterior, Interior), TAS Building Code, and Archivists' Notes.
Todd Webb was commissioned by the Amon Carter Museum (ACM) to professionally photograph selected sites and buildings, using information from Field Director Garner's initial survey work. Todd Webb (TW) recorded extensive shot logs, detailing trip sequences (labeled A-H) and roll numbers for his 120 mm film. Todd Webb also worked with 4x5 inch film, 5x7 inch and 8x10 inch film, recording detailed images of hundreds of Texas buildings. His entire body of work is in black and white, consisting of 3,609 frames. Frequent building types photographed include county courthouses, churches, and historical homes from nineteenth-century Texas.
To locate buildings, cities, counties, or construction styles of interest:
The ACM initially cataloged all Todd Webb negatives, assigning sequential accession numbers to 819
photographic shot locations (P1977.12.1-819), encompassing a total of 3,609 frames.
The following
Provenance is unknown for the Todd Webb print numbers that appear on the reverse of select enlargements in Subseries C6.
Researchers interested in the exhibition history of Todd Webb's work should contact the Archives of the Amon Carter Museum of Fort Worth, Texas.
The paper card index, arranged alphabetically by town or city, lists every building and location photographed by Todd Webb using 120 mm film. The creator of the index is unknown. The index cards provide the city, subject matter, Todd Webb film roll number, and frame number (for example: GALVESTON, Interior Stairway of old Federal Courthouse, Roll 7C, frames 1-5). This information can be used to locate the image on the Todd Webb contact sheets, which are arranged by Rolls 1-35, then Rolls A-H, with every roll given a number (for example: Roll A2, A3). This subseries also includes a folder of photographic listings.
Three different, unique sets of contact sheets were printed from Todd Webb's 120 mm film negatives. Provenance for each set is unclear, although they may have been used for editing purposes to compile images for the two book publications or two museum exhibitions. Set 1 contains accompanying shot logs (typed) detailing the subject and location of images. A copy of the shot log (titles) for the negatives can also be found in the Administrative Records of the Amon Carter Museum, in Subseries A2.
The complete set of black and white contact prints for all large format negatives from ACM accession number negatives P1977.12.303 through P1977.12.819. Most of the individual prints are labeled with an adhesive label from the Amon Carter Museum (ACM).
Some Webb prints were originally stored in binders at the ACM, prior to the transfer to the Alexander Architectural Archives in 2002. These prints may have been work or study prints for internal use at the Amon Carter or by the Texas Architecture Survey, as a printing date is not indicated. Some prints are contact prints. There are frequent duplicates. Many prints include Amon Carter accession numbers and some include Todd Webb shot roll numbers. All prints are black and white. Loose prints are arranged alphabetically by city.
Several indices are available to all Todd Webb negatives, including searchable electronic resources (see below). Photographic negative size formats consist of 120 mm, 4x5 inch, 5x7 inch, and 8x10 inch black and white negatives shot by Todd Webb in 1966. He recorded 3,609 frames. When working with 120 mm film rolls, Webb often captured 9 or 12 image frames per roll.
Negatives are arranged sequentially by Amon Carter Museum accession number. The ACM number incorporates the roll and frame number of every image. The 120 mm roll film negatives were given accession numbers in the range (P1977.12.1-302), but individual negatives are identified by the additional suffix number 1 through 9, which corresponds to the handwritten number present on the contact sheets (for example P19220.127.116.11 refers to Roll #136, Frame 8). Larger format negatives have been assigned these accession numbers: P1977.12.303-326 (8x10 inch), P1977.12.327-681 (5x7 inch), and P1977.12.682-819 (4x5 inch). The photographic negatives are not stored in alphabetical order by city, but in sequence by Amon Carter accession number.
An electronic spreadsheet index for all Todd Webb negatives is available in two formats, please
click to download a
Arrangement: alphabetical by Texas county, then by city
Twelve oversize boxes house 10x13 inch enlargements (289 prints) of select Todd Webb prints. The selection decision for printing these images is not clearly documented in the collection, but these are a representative sampling of the Webb's work done for the two books and two exhibitions. Additional information can often be found on the reverse of prints (such as a numbering system with examples like "TW-217") and has not been included in this finding aid. Some prints are mounted on boards while other prints are unmounted. There are duplicates among the prints and across multiple boxes. The prints have been re-arranged since original receipt and are now stored alphabetically by Texas county. Documentation listing original receipt order has been saved and is included in the records.
Little is known about Gus Cranz of Fort Worth, Texas. His photographic collection appears to have been acquired by the Texas Architecture Survey and Amon Carter Museum during its operations. Original ACM binder storage numbers are written on the folders to preserve original order as received.
An index to Gus Cranz prints is available in two formats to download, click to select a
Note: all prints are sleeved (sleeve has not been determined as archival yet) and some items have a sticker with a handwritten number.
In his "student research report to Professor Kermacy" (1964), Field Director Garner notes that:
Garner continues writing, saying that,
Records do not clearly indicate if this plan was successfully completed, as there is no clear original order or detailed identification for the prints.
Note: some prints have other prints mounted verso. These include images of Austin and San Augustine.
The Texas Frontier Architecture File (1937, 1964) includes sixty-six files arranged alphabetically by county, fronted by one file entitled Texas General. The folders contain 191 black and white prints, 44 negatives, printed material, notes, and maps possibly associated with previous survey efforts by the National Park Service. These items were donated directly to the repository by John Garner.
This series also includes a reference file that possibly belonged to Professor Blake Alexander, with working prints from Todd Webb (with other photographers possibly present).


text:
STROUDSBURG, Pa. (AP) – Authorities say one person is dead after a fire broke out at a Stroudsburg apartment complex that is home to many senior citizens.
Police say the fire started in a fifth-floor apartment in the Westgate Apartments around 8:45 p.m. Thursday and was mostly contained to that part of the building.
Residents were quickly evacuated, but Stroud Area Regional Police say one person is dead.
Firefighters had to carry some residents down from upper floors because they were in wheelchairs or weren't able to walk down the stairs.
More than 100 people live in the building.
Authorities say residents have been evacuated to the a nearby high school gymnasium.


text:
We are going to my cousin's in Jerusalem as we do every year and we always bring the charoset, chicken soup with matza balls and dessert. I always try to bring a different dessert.
I am still trying decide what to bring this year. Maybe one of these:
- Torta di Carote from the Veneto region
- Persian Rice Cookies
- Super Moist Banana & Almond Cake
- Chocolate Almond Torte with cinnamon, allspice, cloves and a dark chocolate glaze
Last year I made Gâteau à l'Orange et au Gingembre from one of my favourite blogs, Chocolate & Zucchini. It is a moist cake that has an intense orange and ginger flavour. I might be tempted to make it again this year. It was a huge hit. And, it is very easy to make.
Orange and Ginger Cake From Chocolate and Zucchini
3 small oranges or 2 large oranges (preferably organic)
6 eggs
250g (1-1/3 cups) sugar
250g (1-1/3 cups) almond flour or almond meal
Thumb-sized knob of fresh ginger
1/4 C candied ginger
1 teaspoon baking powder
Zest and juice of a lemon
60 g (1/3 cup) thick sugar crystals, the type used as a topping for chouquettes or brioches
Preheat the oven to 190°C (375°F). Grease a 24 cm (8-inch) springform cake pan.
Clean and scrub the oranges well. Put them in a medium saucepan, and cover with water. Put the saucepan over medium heat, and simmer for two hours, adding a little hot water when the level gets too low (note : you may, like me, find the smell of whole oranges boiling very unpleasant, but it has nothing to do with the smell or taste of the finished product). Drain, and let cool. Cut in quarters and puree in the food processor.
Peel and chop the fresh ginger. Cut the candied ginger in small dice. In a large mixing bowl, beat the eggs with a fork. Whisk in the orange puree, the sugar, the almonds, the baking powder, the fresh ginger, until well blended. Fold in the bits of candied ginger.
Pour the batter in the cake pan, and bake for about an hour, until puffy and golden. Let cool for a few minutes on a rack, while you prepare the frosting. Run a knife around the cake to loosen it, and remove the sides of the pan.
Put the sugar crystals in a small bowl with the lemon juice and zest. Spoon this mixture evenly onto the top of the cake. Let cool completely before serving. It can be made a day ahead, wrapped in plastic and stored in the refrigerator.
The second dessert I made were chocolate-covered Weesper Moppen, which are Dutch almond cookies. They are chewy cookies with a wonderful almond flavour which can be made plain and rolled in coarse sugar or covered in dark chocolate. I like them because they are not very sweet.
250g (8oz + 2 tablespoons) coarse almond paste or grind 125g//1/2 cup of blanched almonds and 125g (1/2 cup) of fine sugar
1 tsp lemon zest
1 small egg
200g (8oz) 80% dark chocolate (Valrhona or some other premium brand), melted
Mix everything except the chocolate together until you have a soft paste.
Wet your hands with cold water, and roll the paste into log. It will still be very sticky and a bit hard to manage. You could roll them in a little kosher for Pesach icing sugar or put the dough in plastic wrap and roll it into a log and place into the refrigerator for 10 minutes to firm up a little.
With a sharp knife (wipe it between cuts) cut the dough into 20 rounds about 1/2 inch or 1cm thick. Place them cut side down on a baking sheet lined with baking parchment or a silpat liner.
Let them dry out for about 2 hours. I put them in a cold oven, with the fan on, for one hour, which worked excellently!
Then, preheat the oven to 200 C / 375 F. When the oven is hot, bake the cookies for 8-10 minutes. Check that they don't brown too much. Remove them from the sheet, let them cool.
After they have cooled, dip them in the melted chocolate. You can either cover the entire cookie or just one side.
They will dry out a bit more as they cool, but they should still be slightly chewy. They are best served the same day or the following day.


text:
originally posted in:Forerunners Descent
We have exactly 4 months till we are finally roaming and firing up our swords into battle. This is our final countdown till BLAMING!-BLAST OFF!!, So Do not lose this Flame, Keep it held deep within your soul Until THAT DAY!. And let it go. Our eyes are no longer Starside, nor Cloudside, nor Earthside...It's FORERUNNERS DECENT-SIDE. "Hoorahhhh!" NINJV-(2nd Commander). "The link above is what I shall represent in battle"
Posting in language:


text:
There is no argument. I'm not even going to get into that conversation. You're stealing! It's stealing, that's what it is. It's not free for us to make these records. These records are on sale in many, many places where you can pay your money to buy the product that we are selling. Anything outside of that is stealing. There is no conversation to be had. There's no, "Well, I just wanted to check it out, and then I liked it so I bought the record." I don't give a fuck. It's stealing. Everyone can say that, "I just wanted to check it out," or "There's no way for me to get music where I live." That's bullshit. It's fucking bullshit! I've been doing this for way too long. I sold records in the '80s and '90s before there was an Internet, and no one seemed to have a problem going out and buying a shit ton of records back then. The whole record industry has collapsed because people are stealing. That's the end of the story.Actually, the whole record industry has collapsed because the market has determined that the product they are selling is not worth very much. This whole time, musicians seem to have convinced themselves that their product was their music.
Not so. Their product was their brand, and the most valuable thing about it was the packaging. Thanks to technology and changing social attitudes, the packaging of music just isn't as valuable as it used to be. Absent the packaging, what are you getting exactly? A copy of a recording, and it's not even a true copy. It's a copy made up of little slices of the original sound, and your ear is so dumb it can't tell the difference.
You want me to pay you for that? Well, alright...but don't expect very much for it.


text:
Get Rid Of Warts
- November 19, 2012
( 4)
ATTENTION: All wart sufferers, this is the day to stop the shame....How I Cured My Warts Forever... And How You Can Cure Yourself Of Warts Naturally In 3 Days! With No Blisters, No Scars, And No Pain ! Without medication or expensive procedures 100% natural treatment of warts, Cure planters warts,Genital warts, mouth warts, warts on your neck,warts on hands, warts on fingers,warts on face, warts on toes. Cure all types of warts, find out what causes warts ? Effective natural treatment of warts !
Thank you


text:
Wallabies selectors should judge Christian Lealiifano on his impressive start to the Super Rugby season and not on his one-on-one battle with Berrick Barnes tomorrow night, ACT Brumbies coach Jake White says.
Lealiifano has put himself in contention for Test selection after leading the Brumbies to the top of the Australian conference after nine Super Rugby games, but faces a potential road-block tomorrow night against Barnes, a proven Wallabies flyhalf. The Brumbies have scored 16 tries in their past three matches and Lealiifano has been instrumental in the attacking onslaught.
Lealiifano started the season at inside centre, but made a permanent move to flyhalf when Matt Toomua ruptured his anterior cruciate ligament at Canberra Stadium in March.
His form has convinced White that the 24-year-old playmaker is ready to step up to the Test rugby arena.
''I'd like to believe what Christian has shown in the past couple of weeks is not going to get judged on one Saturday against Berrick Barnes,'' White said.
''Anyone who has watched him the whole season knows that [he's in good form] and I'd like to believe he won't get judged on one performance.
''He just has to keep doing what he's been doing and if he focuses on those things, everything will fall into place.''
The Brumbies have named the same back line for the third consecutive match.
While their back line is beginning to fire, constant injuries have forced the Waratahs to re-shuffle and they're still trying to their combinations.
Former Brumby Adam Ashley-Cooper has been named at fullback again and will pose a constant threat when the Waratahs attack. Barnes has moved to flyhalf after beginning the season at inside centre.
But Brumbies and Wallabies inside centre Pat McCabe expected the Waratahs back line to finally click in defence and attack.
''We've seen what they did last week [against the Crusaders] … if they defend with the same formation they'll be a lot better for the run,'' McCabe said.
''With combinations the first week is by far the hardest in getting an understanding of what guys do and getting comfortable each other. But if we run the plays we want to, hopefully we'll have some success.''
The Brumbies haven't beaten the Waratahs since 2009 and McCabe - yet to record a victory over NSW - said there was an ''extra edge'' and hype around the interstate match.


text:
"We need to win a game. Playing on the road in six of your first 10 is not easy," said Bill Self. "We are 3-3 and the road. We will welcome coming home and I hope the fans will welcome the guys. They need a pick-me-up."
The Jayhawks are fresh off their worst week of the season, losing to Oklahoma State by 20 on Monday night and at unranked Nebraska by 19 on Sunday afternoon. KU has now lost three straight road games. The Jayhawks hadn't dropped consecutive league games by double-digits since losing to Oklahoma (95-72) and Oklahoma State (85-74) under Ted Owens in 1983.
"Winning on the road in any league is hard to do when talent is relatively comparable. You have to be really good when you go away from home," said Self.
KU, which is 4-4 in its last eight games, hopes to find a cure for its recent woes in the friendly confines of Allen Fieldhouse, where the team hasn't played since a commanding 96-77 win over Texas Tech on Feb. 7.
"Confidence is a weird thing and right now we are just not as confident as we were a week ago. That is obvious. Good performance and good practice can change that overnight," said Self.
The Bears (7-16 overall, 2-8 Big 12) have also lost two straight games, and are coming off a 91-58 defeat at Oklahoma State on Saturday. The Jayhawks are undefeated all-time against Baylor in Lawrence (5-0).
"If we think Baylor will be easy -- that is not the case at all," cautioned Self.
Wednesday's meeting will be the 10th all-time between Kansas and Baylor, with the Jayhawks holding an 8-1 series lead.
KU's three-point shooting is steadily improving at 36.4 percent in its last five games. However the Jayhawks are suddenly struggling from the free throw line with 62.5 percent in their last five games.
Simien has been a beast as of late, averaging 18.6 points on 55.9 percent shooting over the team's last five games, while Miles' numbers in conference play are impressive -- 8.2 points, 4.1 rebounds and 8.8 assists per game. Langford's scoring has been down recently, as he's averaging just 12.0 points on 41.1 percent shooting over his last five contests. Kansas' defense is allowing 65.9 points per game on 38.7 percent shooting from the floor.
BU scores 64.9 points per game on 41.8 percent shooting from the field. Terrance Thomas paces the Bears with 16.6 points per game on 40.6 percent shooting from the field, while also grabbing a team-high 7.4 boards per contest. Harvey Thomas chips in with 15.9 points per game on 40.6 percent shooting from the floor.
"I haven't seen any of their guys play," said Self.
"They have done a good job down there, holding it together. They have some momentum now. If I was a Baylor fan, with all of the stuff they have gone through and looking for a fresh start, I would be really proud to be a guy who supports the program."
Baylor is coached by Scott Drew, who is 7-16 in his first year with the Bears, 27-27 in his second season as a head coach overall.
"I think Scott (Drew) is doing a great job," said Self.
"They are very athletic is some spots. They will do some things that are a little different. The guards will screen for the bigs to get perimeter shots and they will play a lot of zone."


text:
Cielito by Kristen Jancuk
Welcome! You are browsing as a guestWould you like to see 7 projects made from this pattern and much more? create a free account What am I missing?
© lizkwan
This pattern is available for $5.50 USD
buy it now or visit pattern website
buy it now or visit pattern website
Cielito is a versatile baby blanket inspired by the dancing clouds and bright stars of an endless sky. It features a zig zag garter stitch border at top and bottom, framing a complimentary central stitch pattern--diagonally traveling columns of eyelets bordered by small star stitches. The sample was worked up in a tonal yarn, but try a tweed or heathered yarn for a different look!
Directions are both charted and written.
For more information, see: http://www.knitpicks.com/patterns/Cielito_Baby_Blank...


text:
The Second Tuesday Race Forum is a place to learn about Race in our lives through monthly conversations about Race. Look at the pictures from our meetings and have a look around the site; at About Us, at the Blog and the Resources Pages.
We are always open to new members. Go to our Contact page to see how you can join us by trying out a meeting or by signing up for our email list.
Talking about Race can be a scary thing. We can't promise you will always be comfortable, but we can say that you will be safe from harm.


text:
udoh etido
Black Squire - Poem by udoh etido
Dark wings, dark words;
bring back what is lost;
Dark wings, dark words;
fly from the east to the north.
Let your flight be sudden;
let the dawn be sullen;
Dark wings, dark words;
fly to deliver strange thoughts.
Mortal grief abound;
moments of sorrow surround;
only your wings shall be on course;
even defying cosmic hailstorms.
Black as the night;
swift as the dart;
wings of justice;
sometimes breaks our promise.
Dark wings, dark words;
an ancient's message to the dust;
Convey messages through the realm;
blurt the sky with your whim.
Scavengers fill the sky;
waiting to thwart your flight;
Snows cover the mountains;
making strange beards on her face.
Dark wings, dark words;
a proverb to the lost;
Deciphering every vile and sorrow;
where life can never be hollow.
A strange creature you are;
a strange message in your hands;
Dark chains on your neck;
wool strapped to your legs.
Kings beseech thee;
maidens crave your speech;
Castles anticipate your landing;
on her walls filled with magic.
The realm is all for thee;
even riders cant beat your speed;
Let your messages filter the lands;
let your wings dispatch great sounds.
Dark wings, dark words;
message for the wildlings behind walls.
Dark wings, dark words;
the crow beats them all.
Form: epic
Comments about Black Squire by udoh etido
Read this poem in other languages
This poem has not been translated into any other language yet.
I would like to translate this poem »
udoh etido's Other Poems
Famous Poems
Phenomenal Woman
Maya Angelou
Still I Rise
Maya Angelou
The Road Not Taken
Robert Frost
If You Forget Me
Pablo Neruda
Langston Hughes
Annabel Lee
Edgar Allan Poe
Caged Bird
Maya Angelou
Rudyard Kipling
Stopping By Woods On A Snowy Evening
Robert Frost
A Dream Within A Dream
Edgar Allan Poe


text:
Motlow College Foundation and Advancement Office
Ms. Jan Casey Rogers
Director of Advancement
(931) 393-1692
(800) 654-4877 Ext. 1692
Motlow College Foundation Scholarships
SCHOLARSHIP HONORING RUTHERFORD COUNTY INDUSTRIAL DEVELOPMENT BOARDThis scholarship is to be awarded one time only in the amount of $1500. Application deadline is August 30, 2013 and will be awarded on October 15, 2013.
- Applicant must be enrolled as a full-time student in the Mechatronics program at Motlow College, Smyrna/ Bridgestone, Lavergne.
- Applicant must reside in Rutherford County.
- Minimum GPA of 2.5 is required
How to Apply:
Complete the following application: Rutherford County Industrial Development Board Scholarship Application
Mail completed application to the following address:


text:
Arthritis & Rheumatism, Volume 63,
November 2011 Abstract Supplement
Abstracts of the American College of
Rheumatology/Association of Rheumatology Health Professionals
Annual Scientific Meeting
Chicago, Illinois November 4-9, 2011.
Vibratory Sense in Patients At High Risk of Knee Osteoarthritis.
Thorlund1, Jonas B., Shakoor2, Najia, Ageberg3, Eva, Sandal1, Louise F., Block2, Joel A., Roos1, Ewa M.
Research Unit for Musculoskeletal Function and Physiotherapy, Institute of Sports Science and Clinical Biomechanics, University of Southern Denmark, Odense, Denmark
Rush University Medical Center, Chicago, IL
Department of Health Sciences, Lund University, Lund, Sweden
Patients with knee osteoarthritis (OA) have impaired proprioception and vibratory sense. Vibratory sense is a separate yet closely related sensory pathway to proprioception, but is able to be more reliably tested than proprioception. It remains unclear if sensory deficits, which may alter neuromuscular activity and affect mechanical knee joint load, precede or follow as a consequence of OA. Young patients with previous anterior cruciate ligament injury are at high risk of knee OA. Furthermore, middle-aged patients with degenerative meniscus tears are suggested to be at high risk of knee OA or have early changes of knee OA. As such, they represent two distinctly different groups of patients to study early factors involved in OA pathogenesis. The aim of this study was to investigate the hypothesis that patients at high risk or with very early changes of knee OA would already display characteristic OA sensory deficits compared with age-matched controls.
Patients: 39 ACL injured patients (ACL) (24.0±5.2 yrs, BMI 24.0±2.9 kg/m2, time since injury 21.9±21.6 month) were compared with 28 controls (ACL-C) (25.6±4.4 yrs, BMI 23.6±2.2 kg/m2). Furthermore, 22 patients meniscectomized for a degenerative tear (APM) (49.6±4.8 yrs, BMI 24.7±2.7 kg/m2, time since surgery 49.6±5.0 month) were compared with 25 controls (APM-C) (49.4±5.2 yrs, BMI 25.2±4.9 kg/m2).
Self-reported outcomes: The Knee Injury and Osteoarthritis Score (KOOS) was used to assess knee-related pain, symptoms, function in daily life (ADL), sports and recreation function (Sport/Rec) and quality of life (QOL). Separate subscale scores from 0 to 100, worst to best, were calculated.
Vibratory perception threshold (VPT): VPT was assessed using a biothesiometer at two different sites (i.e. the most prominent point of the medial malleolus (MM) and the medial femoral condyle MFC)). The mean of two measurements was noted as the VPT (i.e. higher value indicates worse vibration sense).
ACL self-reported substantially worse than ACL-C on all KOOS subscales (p<0.001). APM self-reported worse QOL (p=0.007) than APM-C and a tendency for more pain (p=0.079) and symptoms (p=0.084) than controls. No difference was observed between APM and APM-C in ADL and Sport/Rec. In contrast, no evidence of somatosensory deficit was observed in either the ACL or the APM group. Linear regression (adjusting for age and sex) showed no sign of sensory deficits (i.e. increased VPT score) in ACL compared with ACL-C at either of the two sites (MM: 9.4 (8.6 10.3) vs. 11.0 (9.7 12.3) volts, p=0.034 MFC: 15.7 (14.0 17.5) vs. 18.1 (15.8 20.4), p=0.122 in the patients and controls, respectively) or in APM compared with APM-C (MM: 14.4 (12.2 16.6) vs. 16.6 (13.6 19.6), p=0.182 MFC: 18.9 (15.9 21.9 vs. 23.0 (19.3 26.8), p=0.092 in the patients and controls, respectively).
These data do not support the hypothesis that sensory deficits precede overt OA in post-traumatic OA, at least in young ACL-injured patients and middle-aged meniscectomized patients at high risk or in the very early phase of knee OA. Further study is necessary to distinguish the time course of somatosensory loss in OA.
To cite this abstract, please use the following information:
Thorlund, Jonas B., Shakoor, Najia, Ageberg, Eva, Sandal, Louise F., Block, Joel A., Roos, Ewa M.; Vibratory Sense in Patients At High Risk of Knee Osteoarthritis. [abstract]. Arthritis Rheum 2011;63 Suppl 10 :1088


text:
"Rays Word of the Day" CONTEST
- General. By participating in this contest, sponsored by WWSB-TV/ABC 7 ("The Station"), the participant and entrant acknowledge and agree to all of these Official Rules. NO PURCHASE NECESSARY. Void where prohibited. Contest begins at 5:00PM on APRIL 25, 2013 and ends at 11:59PM on SEPTEMBER 19, 2013. All times in this contest refer to Eastern Standard Time. By entering the contest, participants and entrants agree to waive any right to claim any ambiguity or error in these Official Rules, or the contest itself, and agree to be bound by these Official Rules and by all decisions of The Station, whose decision is binding and final in its sole judgment and discretion. The Station reserves the right to withdraw the transmission of this contest and award the prize from among entries received prior to the date of the withdrawal. The Station also reserves the right to amend these contest rules, including retroactive amendment, at any time. Failure to comply with these rules may result in disqualification from this contest.
- Eligibility. All Entrants must reside in The Station's Designated Market Area (DMA) as defined by Nielsen. Those counties include: Sarasota, Manatee, Charlotte, Desoto, Hardee, Citrus, Hernando, Highlands, Hillsborough, Marion, Pasco, Pinellas, Polk and Sumter. All Entrants must be 18 years of age or older as of April 25, 2013. Employees of The Station, contest sponsors, their respective parent companies, subsidiaries, affiliated companies or agencies, officers, directors, agents and members of their immediate families and household are not eligible.
To claim prize, each Weekly Winner must present a valid Photo ID at WWSB-TV in Sarasota. Failure to provide proper identification constitutes forfeiture of prize.
- How To Enter. To enter, viewers must watch ABC 7 News every Thursday between 11:00pm-11:35pm April 25, 2013 through September 19, 2013 for the "Rays Word of the Day". Viewers must then visit MySuncoast.com and enter that day's correct word by 11:59PM that night to be eligible for the daily prize. As part of the entry/registration process, the Participant must enter his/her first and last name, address, phone number and email address. Participants may only enter the contest once per week. Odds of winning depend on the number of eligible entries received.
On each week of the contest, the Weekly Winner will be selected by random drawing from all correct entries received that week.
- PRIZES. There will be two weekly prizes. The prize will include two tickets to a Rays game.
Prizes cannot be exchanged for cash, and restrictions may apply to prizes. The Station makes no warranties with regard to the prizes. Transfer of any prize is prohibited. All taxes and other expenses, costs or fees associated with the acceptance and/or use of the prize are the sole responsibility of the winner. The Station reserves the right to substitute a similar prize of equal or greater value at its sole discretion. Each winner must be approved by The Station, in its sole judgment and discretion, and complete an affidavit of eligibility and liability release or the prize will be forfeited and alternate winner selected. If any sponsor withdraws support for the contest, The Station is not responsible for continuing the contest.
- Notification of Winners. Winners will be notified by telephone or email at the phone number or email address provided by the Participants. Winners will be required to sign and return to the Sponsor an affidavit of eligibility and liability release. If any prize notification is undeliverable, or in the event of non-compliance with any of these requirements, the prize will be forfeited, and an alternate winner will be selected at random from the remaining eligible entries.
- Disclaimer. The Participants and Entrants of all winning entries assume all liability for any injury or damages caused or claimed to be caused by his or her participation in the contest and/or the acceptance and/or use of any prize, and releases The Station, contest sponsors, their respective parent companies, subsidiaries, affiliated companies or agencies, officers, directors, agents and employees, from any such liability. The Station, contest sponsors, their respective parent companies, subsidiaries, affiliated companies or agencies, officers, directors, agents and employees are not responsible for technical, hardware, software, or telephone malfunctions of any kind, lost or unavailable network connections, or failed incorrect, incomplete, inaccurate, garbled or delayed electronic communications caused by the user or by any of the equipment or programming associated with or utilized in this contest or by any human error which may occur in the processing of the entries in this contest. Entry constitutes permission (except where prohibited by law) to use winner's name, city, state, likeness and/or voice for purposes of advertising, promotion and publicity without additional compensation. The winner's name and city of residence will be posted online and mailed to those who request it.
- Internet. If the contest is not capable of running as planned for any reason, including infection by computer virus, bugs, tampering, and unauthorized intervention, fraud, technical failures, or any other causes beyond the control of The Station which corrupt or affect the administration, security, fairness, integrity of the contest, The Station reserves its right in its discretion to disqualify any individual it believes has tampered with the entry process, and/or cancel, terminate, modify or suspend the contest. The Station, contest sponsors, their respective parent companies, subsidiaries, affiliated companies or agencies, officers, directors, agents and employees are not responsible for any error, omission, interruption, deletion, defect, delay in operation or transmission, communications line failure, theft or destruction or unauthorized access to, or alternation of, entries: (ii) are not responsible for any problems or technical malfunction of any telephone network or lines, computer on-line systems, servers, or provider, computer equipment, software, failure of any email to be received by The Station on account of technical problems, human error or traffic congestion on the Internet or at any website, or any combination thereof, including any injury or damage to the Participant's or any other person's computer related to or resulting from participation or downloading any materials in this contest.
- Terms of Use Agreement & Privacy Policy.
- By entering this contest, you agree to the use of your personal information as described at:
- By entering this contest, you agree to the use of your personal information as described on our contest page:


text:
Robert E. Lee on Leadership
Robert E. Lee on Leadership
Executive Lessons in Character, Courage, and Vision
Crown Forum, Paperback, 9780761525547, 256pp.
Publication Date: August 24, 2000
-A masterpiece--the best work of its kind I have ever read. Crocker's Lee is a Lee for all leaders to study; and to work, quite deliberately, to emulate.- -- Major General Josiah Bunting III, superintendent of the Virginia Military Institute
In this remarkable book, you'll learn the keys to Lee's greatness as a man and a leader. You'll find a general whose standards for personal excellence was second to none, whose leadership was founded on the highest moral principles, and whose character was made of steel. You'll see how he remade a rag-tag bunch of men into one of the most impressive fighting forces history has ever known. You'll also discover other sides of Lee--the businessman who inherited the debt-ridden Arlington plantation and streamlined its operations, the teacher who took a backwater college and made it into a prestigious university, and the motivator who inspired those he led to achieve more than they ever dreamed possible. Each chapter concludes with the extraordinary lessons learned, which can be applied not only to your professional life, but also to your private life as well.
Today's business world requires leaders of uncommon excellence who can overcome the cold brutality of constant change. Robert E. Lee was such a leader. He triumphed over challenges people in business face every day. Guided by his magnificent example, so can you.
"A masterpiece—the best work of its kind I have ever read. Crocker's Lee is a Lee for all leaders to study; and to work, quite deliberately, to emulate."
— Major General Josiah Bunting III, superintendent of the Virginia Military Institute
"A splendid and inspiring book, Robert E. Lee on Leadership offers enormously valuable lessons for all of us today, and should be required reading in the White House, the State Department, and the Pentagon, at least."
— Caspar Weinberger, former Secretary of Defense, chairman of Forbes magazine
"As Harry Crocker reminds us, the principles that guided Robert e. Lee were grounded in the finest traditions of American values. Robert E. Lee on Leadership is a timely and valuable reflection on character, and on the personal and spiritual convictions that make for great leaders."
— S. Patrick Presley, director of Federal Government Affairs, British Petroleum
"A moving and illuminating look at Lee the man, so that thoughtful people can learn from him how to succeed in the business of life."
— Dinesh D'Souza, author of Ronald Reagan: How an Ordinary Man Became an Extraordinary Leader
"Harry Crocker has provided a great service by reminding us through this moving and tightly written biography that winning isn't the only thing: faithfulness and honor live in our memories after the guns are silent."
— Marvin Olasky, author of the bestselling Renewing American Compassion and The American Leadership Tradition


text:
Celebrity Inspired Handbags | Celebrity Bags
Perfect place to buy handbags, wallets and purses inspired by the designers. Find Tote bag, clutch bags, shoulder bags at wholesale price - all in one place.
Shop online for studded handbags, designer bags at low price at Bag INC. These studded handbags are perfect for the rocker chick in all of us! Studs are a hard, solid that makes you the center of attention.Tags: designer handbags, cheap wholesale handbags, celebrity inspired handbags, Shoulder Handbags, Handbags for Sale, studded handbags, rocker chick shoulder bag, cheap designer bagAdded 6 Years Ago from Baginc