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State Backs Activists In Challenging Vermont Yankee License
05/25/11 7:34AM By John Dillon
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(Host) The state of Vermont has joined anti-nuclear activists in a legal challenge to Vermont Yankee's new 20-year operating license.
The state says the Nuclear Regulatory Commission skipped a step when it issued the license extension in March.
VPR's John Dillon has more:
(Dillon) At issue is a Clean Water Act permit that the state says is required in order for the NRC to grant Yankee the license extension.
The state administers the Clean Water Act, and it says Yankee does not have approval under section 401 of the act for its site on the Connecticut River.
Natural Resources Secretary Deb Markowitz says the NRC needs to withdraw the license extension until Yankee shows that it has complied with state and federal water quality laws.
(Markowitz) "To get a new license the Entergy power plant has to have a section 401 certification. And so what we did was file a petition for review in the DC circuit seeking to overturn the federal NRC license based on this narrow issue - that the license had been issued even though Entergy hadn't sought or received a section 401 certificate."
(Dillon) Markowitz said the legal action was not linked to Yankee's federal lawsuit that challenges the state's authority over the nuclear power plant.
(Markowitz) "It's a technical deficiency in the license. And we filed the petition to protect Vermont's rights under the Clean Water Act to require a 401 permit."
(Dillon) Yankee spokesman Larry Smith said that the company believes it does have a valid Clean Water Act certificate.
(Smith) "The Vermont state environmental agency was very involved in and commented specifically on water quality issues in the NRC's license renewal process for Vermont Yankee. At to our knowledge at no time in that process did they comment whether the certification that we currently have was sufficient."
(Dillon) The state is joined in the case by the New England Coalition, a group that opposes a new license for the Vernon reactor. The coalition's lawyer is Chris Kilian, the Vermont director of the Conservation Law Foundation.
Kilian said the record is clear. Entergy does not have the required Clean Water Act approval to operate for another 20 years past March of 2012.
(Kilian) "So the unlawful act here was issuance of a license without a water quality certification. And at this juncture, Entergy Vermont Yankee hasn't even applied for a water quality certification."
(Dillon) Kilian says the water quality approval is needed for any potential discharges from Yankee's Vernon site, including stormwater run-off.
He says a previous water quality certificate - first granted when the plant was built 39 years ago - may not take into account more recent pollution issues, such as discharges through groundwater contamination from radiation leaks.
For VPR News, I'm John Dillon in Montpelier.


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Jacques Reymond, chef
I go on my motorbike, that's my big toy. I've always had a bike, since I was 14 years old, wherever I've been in the world. It's a Ducati. I go with my son, who has a Ducati as well. We usually have a three-hour ride going through the Dandenongs up to Gembrook. When you are on these fabulous machines the emotion you get and this immense pleasure of driving this powerful thing that you can control ... You evade yourself completely, because you can't think of anything else than riding your bike. You feel really tired physically but you are in contact with nature, with the air. And there is nothing like taking a nice bend on a motorbike.
Andy Griffiths, children's author
Most likely Santa has come early and bought some bikes for my two daughters, so I imagine we'll spend a fair bit of time on the Williamstown beach bike track. We spend a lot of time down there and the beach as well. There's a nice park across the road too, which my three-year-old is very fond of. To keep cool it would probably be the beach or the little paddle pool in the backyard. You lose hours at the beach, just playing in the sand and paddling, and the girls love going on the rocks looking for shells and things. It's a great way to absorb an afternoon.
Paul Bangay, landscape designer
I like to pack up and go to my place at Woodend, an hour north of Melbourne. It's 800 metres above sea level, so it's always five degrees cooler than Melbourne, which is perfect in summer. I've had it since 1997. It was the old school for Woodend. I've got five acres, which I've converted into gardens, so I can go out into the garden and work. I've put a pool in, so I can sit by the pool. (The best thing) is the peace and quiet, the garden and the sense of space.
Douglas Wegener, department store Santa
Hopefully we'll get some cooler weather because I want to play some golf. I'm a mad golfer. I have a friend who's retired who I can ring just about any time. My favourite (course) would be Morack, because that's the hardest one. It's very challenging. It's not flat, it's got a lot of variety to the fairways and I can't beat it. I play better at other places ... (but) the fairways there are crooked and up and down. I've got a long way to go before I can say I'm reasonable there. I'm trying to break 50 for nine holes, which is not all that good, but that's what I'm aiming at.
Kit Willow, fashion designer
Chilling out seems so rare. I love eating at night when the sun goes down in St Kilda. At any one of the restaurants outside there's a fantastic energy down there and beautiful light. Definitely Stokehouse, and Donovans. Anywhere along the beach is stunning, or even in Fitzroy Street and Acland Street, there's plenty of energy around there. I love going for early-morning walks ... along the beach with my dog, Ushka. And then just lying in a park, like the Botanic Gardens, and just reading. Being able to just read all day, to me, is very, very relaxing.
Nikki McCarthy, Postcards presenter, Channel Nine
We traditionally make the epic pilgrimage down to Sorrento. My parents have a house down there, so we go down for Boxing Day until the end of January. We spend most days doing the same thing, which is just making a picnic lunch, taking it down to the front beach with the kids, and we sit there pretty much from 10.30am to 5pm. I love all the cafes down there, the restaurants. The Baths (restaurant) is great. They've got a balcony that's right on the sand, so you can watch the kids playing while you're having coffee or lunch or dinner.
John So, Melbourne Lord Mayor
To relax I like to spend time, of course, with the family, with the children. Going out for a meal, walking around the city - there are so many interesting places in the laneways, arcades, where you can spend many interesting hours. I love Italian cuisine. I always like to try the different cafes, particularly on Lygon Street - they've got beautiful spaghettis, pizzas, very tempting! I really enjoy gardening. On weekends I like to prune my bed of roses or plant some vegetables. I like the tomatoes. To escape the heat it would be a good idea to spend a couple of hours in a movie.
Jennifer Keyte, news presenter, Channel Seven
We're going to head down to Barwon Heads as often as possible. We have a family beach house there so it's family coming and going over this whole period and with two young children it's the perfect getaway. There's always lots of aunts and uncles and grandparents willing to help and you actually get a chance to put your feet up. It's one of those beach houses where you can curl up on the couch and it doesn't matter if it's raining or blowing a gale or it's 40 degrees outside, you can find a quiet corner.
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5 Job Post Writing Tips to Get the Right ContractorGuest_Blogger | May 15, 2012
One of the most challenging things for clients when they first get started on Elance can be the process of writing a job post. You put up your post, only to find that either no one submits a proposal, or you get dozens of unqualified bids to sort through. In some cases, you might wind up spending hours answering questions about the project from interested contractors, only to come up without a satisfactory prospect. Finding the right contractor on Elance is, in part, reliant on your job post. You need to create a job post that accurately reflects the work you want to have done, as well as the type of contractor you want to do it.
Here are several elements you need to include in your job post if you want to find the right candidate the first time:
1. Create a descriptive job title.
Your job title needs to be succinct, but it also needs to contain some essential bits of information. "Writer needed" might be accurate, for example, but it doesn't tell contractors what kind of writing you need to have done. Try to include at least the specific type of work you need to have done. For example, your title might be "Sales page writer needed," or "Blog post writer needed."
2. List your actual project budget.
One of the more frustrating experiences for clients occurs when they either simply accept the default project budget, or when they put in a budget that doesn't reflect their actual willingness to pay.
If you want to have 50 blog posts written and you list your budget as $500, for example, you're not going to get bids from those contractors whose rates are above $10 per post. That's not a problem if that's the level of writing you're looking for, but if you can afford $20 per post and want higher quality, you've got to set the budget correctly.
3. Include specifics in the job description.
You also need to be specific and detailed in the way you describe your job. Consider the following two examples:
"I would like to have some blog posts written about finance topics."
"I would like to have 50 blog posts of 500-750 words written about personal financial management."
The second example is only five words longer than the first, yet it gives potential contractors a wealth of additional information. It tells the contractors what sort of expertise you're looking for as well as the exact parameters of the job in terms of word count and number of blog posts.
The first job description will likely garner you many bids—perhaps as many as 30 to 50. Most of those bids won't fit your project because you haven't provided a scope. You'll wind up having many discussions with potential contractors about approximate word count and number of posts that could have been avoided with just five additional words in your description.
4. Mention any special requirements.
If you're looking for someone to provide the work in a specific format, say so. For example, if you want contractors to provide the 50 blog posts in Word Perfect format, mention that in the job description. This usually isn't a problem, but some contractors may not have access to the specialized applications or skills you're looking for.
5. Be honest about the potential for additional work.
If you want to try out a bunch of different contractors to see if you can find one that might fit your needs before you hire one long-term, say so. However if you're just sort of testing the waters and it's going to be another year before you're actually ready to start the long-term project, don't dangle that in front of your contractors.
Here's a little secret from the contractor perspective: it's not too hard to tell whether a client is being truthful when they say that a project can lead to additional work. Unfortunately, there are those out there who use this promise of additional work to get reduced rates, with no real intention of giving additional work. Contractors can be a jaded, skeptical bunch at times, and such statements without supporting evidence (such as a long client history on Elance) are likely to be dismissed.
Finding the right contractor on Elance doesn't have to be a long, difficult process. There are plenty of qualified contractors here with the skill sets you need. By putting some real thought into your job posting you'll save yourself the headache of having to search over and over again, or of coming up dry altogether.
About the Author:
Bob Younce is the owner of Composing Business, a freelance copywriting firm currently ranked in the Top 50 writing providers on Elance. Composing Business is dedicated to helping other small businesses get ahead with high-quality, compelling copy. Contact Bob on Elance or visit his website at www.composingbusiness.com.
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June 11, 2012 - 10:24am
very nice post thanks to you for sharing....
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June 13, 2012 - 10:47am
Hi Bob,
This is valuable advice both for buyers and providers. Strange, how just a little bit more targeted effort can actually lead to reaching your goals.
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June 18, 2012 - 8:21pm
Great post! One additional point, from a provider's perspective: Many buyers want work done fast, cheap, and well. Most of the time you can have only two of the three:
Fast and well done (high cost - the provider is making a living wage while focusing on your project )
Fast and cheap (quality often suffers unless the job is a tiny one - provider is doing lots of cheap projects to boost stats or to make ends meet)
Well done and inexpensive (slow turnaround time - provider fits your work in between other projects or is a new provider trying to get his or her profile off the ground)
Best of luck! There are many excellent providers here, and at least one of them is sure to be a great match for your project.
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June 29, 2012 - 12:23amsanakhan87
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November 29, 2012 - 4:52pm
Thank you for so usefull information!
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I went to Växjö in Sweden for two days last week, I had to stay over night since the travelling all the way back and forth between Copenhagen and Växjö is time consuming.
So I was booked into a hotel, but this time I was very much on my own, since Johan who used to live here moved to London.
So after I went out to eat I just took a single beer and headed back to the hotel to do some work instead, I should have had a beer for Johan aswell - and Johan would problably have drunk two, so I would have had to have two for myself aswell... it was good I just went back to the hotel.
Missed Johans company though...


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11083 Hwy D, Louisiana, Missouri 63353
Total inspections: 2
Last inspection: June 11, 2007
Classification: Nitrogenous Fertilizers
Last enforcement: Unknown
Formal enforcement: 0
Informal enforcement: 0
This facility has not been out of compliance in the past 12 quarters.
View detailed information from the Environmental Protection Agency. Note: There are no mandated limits for power plant discharges into waterways for many common chemicals such as arsenic, lead and mercury. However some facilities are monitored for these pollutants by state regulators and report the findings to the E.P.A.


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Lolo Jones agreed to try bobsledding because she needed something to take her mind off the rigors of her Olympic track season.
Three weeks later, she's got a spot on the national team.
Jones, a two-time Olympic hurdler, was one of 24 athletes selected to the U.S. bobsled team Thursday. She's one of six women's push athletes selected, a group that also includes Olympic sprinting gold medalist Tianna Madison.
"I just came out here and kind of needed to get away from track for a bit, kind of wanted to get some motivation," Jones told The Associated Press. "I thought coming out here with the other girls that we could help each other, we could benefit from one another. I could help them with their speed and they could help me with my strength. And just being around them, hearing their goals gave me new goals and refreshed me."
Jones was fourth at the London Games, the second time she's gone to an Olympics and come home without a hurdles medal. She was the favorite for gold at Beijing in 2008, then hit the next-to-last hurdle and finished seventh.
She still plans to compete in hurdles at the 2016 Rio de Janeiro Olympics. Only now, a trip to the 2014 Sochi Games in a bobsled might come first.
"This is a breath of fresh air cool, very cool, cold air," Jones said.
Jones and Madison were among a small number of track athletes invited to Lake Placid for bobsled's push championships this month by U.S. coach Todd Hays. He believed veteran Olympians would, if nothing else, help some of the team's younger competitors and raise team morale.


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Tesis Hukum Manual
On this page you can read or download Tesis Hukum Manual in PDF format. We also recommend you to learn related results, that can be interesting for you. If you didn't find any matches, try to search the book, using another keywords.
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PDF pages: 54, PDF size: 1.34 MB
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Nikki Saeli Model
Lexxxibabe1414Model Female San Diego, California, US
Mayhem # 2569782
About MeIm looking to do some really creative work with some talented photographers. I have a different look if you haven't noticed....Please understand that Lexi is only someone that comes out in pics and I want someone who can help me show her off, ( I am M) Are you able to make me look amazing!?
I am not looking for generic emails. Please tell me about your work and your thoughts with me! I am always adding to the shots I would like in my tags...This is the type of work Im looking for...very edgy - edited - implied shots - semi nude - nude....and my shoots are always tfp currently...willp consider nude for tfp
I am currently looking to start up my own little online empire! Looking for fun and outgoing models to work with in the FETISH world....Love girls with the same curves and build I have!
I am not petite or fragile...I want hot sexy pics!
Have you worked with Lexxxibabe1414? Add Credits for Lexxxibabe1414! >>
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Nikki Saeli Model
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This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/).
The study was conducted to investigate the promoted immune response to ovalbumin in mice by chitosan nanoparticles (CNP) and its toxicity. CNP did not cause any mortality or side effects when mice were administered subcutaneously twice with a dose of 1.5 mg at 7-day intervals. Institute of Cancer Research (ICR) mice were immunized subcutaneously with 25 μg ovalbumin (OVA) alone or with 25 μg OVA dissolved in saline containing Quil A (10 μg), chitosan (CS) (50 μg) or CNP (12.5, 50 or 200 μg) on days 1 and 15. Two weeks after the secondary immunization, serum OVA-specific antibody titers, splenocyte proliferation, natural killer (NK) cell activity, and production and mRNA expression of cytokines from splenocytes were measured. The serum OVA-specific IgG, IgG1, IgG2a, and IgG2b antibody titers and Con A-, LPS-, and OVA-induced splenocyte proliferation were significantly enhanced by CNP (
Vaccination remains the most effective and cost-efficient means to prevent infectious diseases. The latest trend towards novel and safer vaccines utilizes well-characterized antigens, like purified proteins, peptides, or carbohydrates. These so-called subunit vaccines enable the focusing of the immune response to the desired specificity without the risks associated with vaccines based on whole inactivated or live attenuated pathogens. Unfortunately, such subunit antigens are often poor immunogens when administered alone [
However, strong adjuvant activity is often correlated with increased toxicity and adverse effects. The unique capacity of the extract Quil A from the bark of
The ability of biodegradable microparticles to promote vaccine-specific immunity has been recognized for more than 80 years [
Chitosan is a natural nontoxic biopolymer produced by the deacetylation of chitin, a major component of the shells of crustaceans such as crab, shrimp, and crawfish. Recently, chitosan has received considerable attention for its commercial applications in the biomedical, food, and chemical industries [
Five-week-old female ICR mice (Grade II) weighing 18–22 g were purchased from Zhejiang Chinese Medical University Animal Research Center (Hangzhou, China) and acclimatized for one week prior to use. Rodent laboratory chow and tap water were provided
Chitosan (CS) was obtained from the Chitosan Company of Pan'an, Zhejiang, China (degree of deacetylation, 95%; average molecular weight, 220 kDa). Ovalbumin (OVA), concanavalin A (Con A), 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT), lipopolysaccharide (LPS), RPMI-1640 medium, and rabbit anti-mouse IgG peroxidase conjugate were purchased from Sigma Chemical Co., Saint Louis, MO, USA; goat anti-mouse IgG1, IgG2a and IgG2b peroxidase conjugate were from Southern Biotech. Assoc., Birmingham, AL, USA; Quil A was kindly provided by BrenntagNordic A/S, Denmark. Fetal calf serum (FCS) was provided by Hangzhou Sijiqing Corp., Hangzhou, Zhejiang, China. Cytokines (IL-2, IL-10, IFN-γ) detecting ELISA kits were from Rapidbio Lab., West Hills, CA, USA. Trizol was from Invitrogen, China; revert Aid™ M-MuLV reverse transcriptase was from Fermentas, USA; diethylpyrocarbonate (DEPC) and ribonuclease inhibitor were from Biobasic, Canada; oligo (dT)18 were from Sangon, China.
Human leukemia K562 cell lines, sensitive to natural killer (NK) cells, were purchased from the Institute of Cell Biology, Chinese Academy Sciences, Shanghai, China. They were maintained in the logarithmic phase of growth in RPMI 1640 medium supplemented with 2 mM
Chitosan (CS) was obtained from the Chitosan Company of Pan'an (Zhejiang Province, China). The degree of deacetylation was about 95% as determined by elemental analysis, and the average molecular weight of the chitosan was 220 kDa as determined by viscometric methods [
A stock CNP suspension or CS solution with a concentration of 3 mg/mL was prepared. The CNP was sterilized by passing it through a 0.22 μm Millipore filter, CS was autoclaved to remove any contaminant and then analyzed for endotoxin level by a gel-clot
Five-week-old female ICR mice were divided into five groups, each consisting of six mice. Animals were injected twice subcutaneously on the back with CNP at a single dose of 0.15, 0.3, 0.75, 1.5 mg in 0.5 mL saline solution at weekly intervals, and monitored daily for 14 days. Saline-treated animals were included as control and the toxicity was assessed by lethality, local swelling and loss of hair at the site of injection.
Five-week-old female ICR mice were divided into six groups, each consisting of six mice. Animals were immunized subcutaneously with OVA (25 μg) alone or with OVA (25 μg) dissolved in saline containing QuilA (10 μg), or CS (50 μg) or CNP (12.5, 50, 200 μg) on day 1. The boosting injection was given 2 weeks later. Saline-treated animals were included as controls. Splenocytes and sera were collected 2 weeks after the secondary immunization for measurement of OVA-specific antibody, natural killer (NK) cell activity and proliferation assay.
OVA-specific IgG, IgG1, IgG2a, and IgG2b antibodies in sera were detected by an indirect ELISA. In brief, microtiter plate wells (Nunc) were coated with 100 μL OVA solution (25 μg/mL in 50 mM carbonate–bicarbonate buffer, pH 9.6) for 24 h at 4 °C. The wells were washed three times with PBS containing 0.05% (v/v) Tween 20 (PBS/Tween), and then blocked with 5% FCS/PBS at 37 °C for 2 h. After three washings, 100 μL of a series of diluted sera samples (initial dilution 1:50) or 0.5% FCS/PBS as control were added to triplicate wells. The plates were then incubated for 2 h at 37 °C, and then washed three times. Aliquots of 100 μL of rabbit anti-mouse IgG horseradish peroxidase conjugate diluted 1:10,000, goat anti-mouse IgG1 peroxidase conjugate 1:8000, IgG2a peroxidase conjugate 1:8000, and IgG2b peroxidase conjugate 1:8000 with 0.5% FCS/PBS were added to each plate. The plates were further incubated for 2 h at 37 °C. After washing, the peroxidase activity was assayed as follows: 100 μL of substrate solution (10 mg of
Spleen collected from the OVA-immunized mice under aseptic conditions, in Hank's balanced salt solution (HBSS, Sigma), was minced using a pair of scissors and passed through a fine steel mesh to obtain a homogeneous cell suspension. The erythrocytes were lysed with ammonium chloride (0.8%, w/v). After centrifugation (380×
Spleen collected from the OVA-immunized mice under aseptic conditions, in Hank's balanced salt solution (HBSS, Sigma), was minced using a pair of scissors and passed through a fine steel mesh to obtain a homogeneous cell suspension, and the erythrocytes were lysed with ammonium chloride (0.8%, w/v). After centrifugation (380×
Splenocytes (5 × 105 cells/well) from the immunized mice prepared as described before were incubated with ConA (final concentration 5 μg/mL) in 24-well culture plates at 37 °C in 5% CO2. After 48 h, the plate was centrifuged at 1400×
Splenocytes from the immunized mice prepared as described before were seeded into 24-well lat-bottom microtiter plate (Nunc) at 5 × 106 cell/mL in 1 mL complete medium, then ConA (final concentration 5 μg/mL) was added giving a final volume of 2 mL (triplicate wells). The plates were incubated at 37 °C in a humidified atmosphere 5% CO2. After 12 h treatment, cells were collected by centrifugation (380×
As shown in
Data were expressed as mean ± standard deviations (S.D.) and examined for their statistical significance of difference with ANOVA and a Tukey post hoc test by using SPSS 16.0.
As shown in
The endotoxin level in a stock CNP with a concentration of 3 mg/mL was measured to be less than 0.5 endotoxin units (EU)/mL. Therefore, the CNP samples used in this study were excluded from endotoxin contamination. When the animals were administered subcutaneously twice ranging from 0.15 to 1.5 mg at weekly intervals, no harm was observed. Local swelling or loss of hair was not observed in mice at the test doses. The results suggested that the safety dose of CNP used for animals was at least up to 60 mg/kg.
The OVA-specific IgG, IgG1, IgG2a and IgG2b antibody levels in the serum were measured by the indirect ELISA method two weeks after the last immunization (
The effects of CNP on natural killer (NK) cell activity in OVA-immunized mice were shown in
The effects of CNP and QuilA on splenocyte proliferative responses to ConA, LPS and OVA stimulation are shown in
The contents of cytokines IFN-γ, IL-2 and IL-10 in the supernatants from cultured splenocytes in the mice immunized with OVA-CNP were significantly higher than those in OVA and OVA-CS control mice (
As shown in
Immunization has been the most effective way to protect individuals and the community against debilitating infectious diseases, thereby preventing the potential economic losses and morbidity associated with such diseases [
In the previous studies, chitosan particles could activate components of the nonspecific immune system such as macrophages and NK cells, and could induce nonspecific immunity to bacteria, fungi, and tumors [
The cellular immune response plays an important role in the host response to intracellular pathogens by limiting replication and accelerating clearance of infected cells as well as in the generation of both humoral and cell-mediated responses to vaccination. Among the T-lymphocytes, helper T cells induce B-lymphocytes to secrete antibodies, and cytotoxic T-lymphocytes help phagocytes to destroy ingested microbes and to kill intracellular microbes. Humoral immunity, however, mediated by antibodies which are produced by B-lymphocytes, functions by neutralizing and eliminating extracellular microbes and microbial toxins. The capacity to elicit an effective T- and B-lymphocyte immunity can be shown by the stimulation of lymphocyte proliferation response. It is generally known that Con A stimulates T cells and LPS stimulates B cell proliferation [
Evidence now exists to clearly suggest that Th1 or Th2 responses, generated upon antigenic stimulation, can be modulation
In order to clearly establish that Th cell-derived cytokines were involved in the adjuvant activity of CNP, we analysed the Th1/Th2 cytokines secretion profiles in OVA-immunized mice using ELISA. CNP not only significantly enhanced the production of Th2 cytokine IL-10, but also strongly increased the production of Th1 cytokines IL-2 and IFN-γ from splenocytes in the OVA-immunized mice (
Natural killer cells (NK cells) are the type of cytotoxic lymphocyte that constitute the major component of the innate immune system. NK cells and CTL play the important role in the defense against tumors and cells infected by viruses [
Based on the findings presented herein, our data suggested that CNP has immunological adjuvant activity on the specific cellular and humoral immune responses to OVA in mice. Taking account of its natural origin and good biocompatibility, and without lethal toxicity to humans and animals, CNP may be a safe and efficacious adjuvant candidate suitable for a wide spectrum of prophylactic and therapeutic vaccines, for which a balanced and potent stimulation of both the cellular and humoral responses is required. Research on CNP with various types of antigen, including vaccines clinically used in other animal models, verify the adjuvant effect. Moreover, the mechanism of the action of CNP has still not clearly been explained. Therefore, more studies on the mechanism of the adjuvant effect of CNP are needed to elucidate in more detail.
We thank Hongxiang Sun for donating the OVA antigen and antibodies for ELISA test, Jun Liu for technical assistance in gene expression, and Mahmoud Azzam for checking language.
Morphology of chitosan nanoparticles (CNP). (
Effect of CNP on OVA-specific IgG, IgG1, IgG2a and IgG2b antibody titers in OVA-immunized mice. Mice (
Effect of CNP on NK cell activity in mice immunized with OVA. Mice (
Effect of CNP on mitogen- and OVA-stimulated splenocyte proliferation in the mice immunized with OVA. Bars with different letters are statistically different (
Effects of CNP on cytokine production in splenocytes from the OVA-immunized mice. Splenocytes were prepared and cultured with Con A for 48 h. The levels of IL-2, IFN-γ and IL-10 in the culture supernatants were determined by ELISA as described in the text. Values are expressed as means ± S.D. of six animals. Bars with different letters are statistically different (
Eeffect of CNP on the mRNA expression of cytokines and GAPDH in splenocytes from the OVA-immunized mice. Lane M, DNA marker; lane 1, OVA; lane 2, QuilA; lane 3, OVA-CNP (12.5 μg); lane 4, OVA-CNP (50 μg); lane 5, OVA-CNP (200 μg); lane 6, OVA-CS (50 μg).
Sequences of primer used for Reversed Transcript-Polymerase Chain Reaction (RT-PCR). GAPDH, glyceraldehyde-3-phosphate dehydrogenase.
The mRNA expression level of cytokines in splenocytes from the OVA-immunized mice.
|15.0 ± 1.4
|45.6 ± 2.1
|26.6 ± 1.4
|38.8 ± 2.1
|50.6 ± 2.2
|16.0 ± 1.2
|15.8 ± 1.6
|40.4 ± 2.3
|29.0 ± 1.4
|38.8 ± 2.3
|44.0 ± 2.5
|16.0 ± 1.6
|15.0 ± 1.4
|45.0 ± 2.7
|22.4 ± 1.8
|30.4 ± 2.2
|44.8 ± 2.7
|18.2 ± 1.7
Means within a row with different letters (a, b, c) differ significantly (


text:
OPN Specialized allows partners to showcase their expertise in selling and implementing Oracle solutions. Customers select specialized partners because they have the knowledge, experience and commitment to help their business succeed. Oracle teams with specialized partners because they meet stringent competency and business requirements giving them in-depth product and industry knowledge to accelerate the sales cycle and deploy successful implementations.
Specialized partners at the Gold, Platinum and Diamond levels can showcase the depth and breadth of their global implementation resources in our Advanced Specialization program. To qualify for Advanced Specialization, eligible partners must meet standard OPN Specialized business and competency criteria for Specialization, plus have 50 or more Oracle-certified implementation specialists on staff.
Select Specialized OPN members with the confidence that they will deliver the solution you need to solve critical business problems.
Engage with an insightful, knowledgeable partner who is an expert in the defined product or industry area and able to successfully develop, architect and implement an Oracle specific solution.
"Learn how OPN Specialized can help customers select the right partner with the right skills and certifications to support their critical business needs."
Hear what Oracle customers say about their experience of working with a Specialized partner.
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Customers can be confident choosing a partner's Oracle Exastack application and expect:
"Learn why customers value Oracle Exastack Optimized partners."
Many Oracle partners provide solutions that are integrated with one or more Oracle Applications. With Oracle Validated Integration, Oracle customers can be confident that:
OPN partners are rapidly taking advantage of Oracle Validated Integration to position their solutions with proven integration to Oracle Applications.
Note: Partners are responsible for providing first-line support for their solutions and integrations. Oracle will provide support for Oracle products as determined by Oracle Support policy. Inclusion of a partner on this website, and / or achievement of Oracle Validated Integration, does not constitute an endorsement or warranty by Oracle of any partner's products or services.
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text:
Fashion in 50 Seconds 10/10 With Diesel, Diesel Jean's, Diesel Advertisements
Fashion in 50 Seconds 10/10 With Diesel, Diesel Jean's, Diesel Advertisements
The excitement over Diesel's 30th Anniversary party has reached a fever pitch for the fashion media as it would appear that Diesel oriented subjects are literally all anyone can talk about including us.
Renzo Rosso is hosting 17 parties in eight time zones for Diesel's 30th Anniversary — from Tokyo to New York via the likes of Dubai, Zurich, Munich and Oslo — all on Saturday night. We personally are looking forward to the New York party because it is our 25th and it happens to be in Brooklyn.
In addition, Diesel will be selling limited edition 'Dirty Thirty' jeans, which would normally sell for around £200 but the company has dropped the price tag to just £30. Alas even jeans pricing is no longer in dollars.
In other Diesel news WWD has a feature on its unique approach to retailing which differentiates each store to its market making the shopping experience more personal and more culturally appropriate.
And finally, Diesel is publishing "XXX Years of Diesel Communication" a retrospective on their controversial advertising campaigns through the years. But the best tidbit? "My dream is to do a soap opera for the Internet, our very own 'Dallas' in the Diesel spirit, in a modern and fresh way," said Rosso.
Balenciaga has signed a deal with Coty Inc.'s Coty Prestige division to create, develop and distribute fragrance lines under the Balenciaga nameplate. The first fragrance is tentatively slated for a spring 2010 launch.
Shoppers are poor at math J.C Penney's has concluded, doing away with tiered discount systems such as "take another 30% at the register."


text:
Accession Number : ADA455421
Title : The National Shipbuilding Research Program. Environmental and Occupational Safety and Health Inspections: A Guide for Shipyard Managers and Employees
Corporate Author : COLLIER SHANNON RILL AND SCOTT PLLC WASHINGTON DC
Personal Author(s) : Wittenborn, John L. ; Hill, Michael O. ; Austin, Dana M.
PDF Url : ADA455421
Report Date : 29 JAN 1997
Pagination or Media Count : 44
Abstract : This document is intended to provide, in outline form, legal advice concerning the various factors that shipyards should consider with respect to facility inspections relating either to environmental (e.g. clean air, clean water, hazardous waste) or occupational safety and health (hereafter referred to as OSHA l) issues. The outline discusses steps that shipyard legal and environmental department personnel, managers and employees should take generally (even when no particular inspection is expected), as well as steps that should be taken when a particular inspection is anticipated, is occurring, or has recently occurred. The outline is devoted primarily to issues raised by federal environmental and occupational safety and health statutes. Additional requirements imposed by state or local laws may dictate that other steps be taken. These requirements should be considered in implementing procedures for a particular shipyard to follow in the context of environmental or OSHA inspections. Additionally, the outline references various checklists and other materials that should be reviewed in the context of specific types of inspections (e.g. those related to compliance with OSHA, the Clean Air Act, the Clean Water Act, etc.). Finally, a shipyard safety and environmental agency inspection checklist is included as an appendix to this document. This checklist was developed to serve as ready reference for the shipyard contact during an inspection by a safety or environmental agency.
Descriptors : *HEALTH, *INSPECTION, *SHIPYARDS, *SAFETY, JOBS, UNITED STATES GOVERNMENT, AIR QUALITY, SHIPBUILDING, CHECKOUT PROCEDURES, LAW ENFORCEMENT, HAZARDOUS WASTES, MANAGEMENT PERSONNEL, FACILITIES, ENVIRONMENTS, WATER
Subject Categories : Air Pollution and Control
Solid Wastes Pollution and Control
Environmental Health and Safety
Distribution Statement : APPROVED FOR PUBLIC RELEASE


text: Alvin T. Black Alvin is disgusted with Denise. Denise is over Alvin. (This is what happens when I... more »Alvin is disgusted with Denise. Denise is over Alvin. (This is what happens when I try my tonsils at voice acting for animation. Written and produced by me. Character names by me. Both voices provided by me. Animation by GoAnimation.) « less Rafael 'Sito' Henriquez November 26, 2013 72 Views More Info Full Credits Rafael 'Sito' Henriquez Uploader Additional Credits Me Stats & Data 6Funny0Die 72 Views November 26, 2013 Published Category Animation Dumb People Sketch Tags Cartoon sweaty hot wet Up Next: Hammered AUTOPLAY Up Next In: 10 Hammered Nailing it First World Problems First World Problems 2 First World Problems 3 Follow Browse Related Comments 20+ more View All ▶ Rafael 'Sito' Henriquez Vaguely Related Videos Vaguely Related Pics & Words Advertisement Tags: Cartoon sweaty hot wet Advertisement


text:
I noticed an icon in my Gmail sidebar above one of the traditional ads.
I think this is new. Newish. The result is a new type of ad that looks like an email message.
As Google says;
It's a new type of ad that you can save to your inbox or forward on. If you dimiss this ad, you won't see it again."
Have you seen this before?
What do you think of the approach? I quite like it; it feels like a natural social ad and has the potential to be a word of mouth/recommendation too. At the same time it doesn't get in the way of my Gmail experience and does not feel creepy.


text:
Vijay Shanker
Adjunct Associate Professor of Law
Email: firstname.lastname@example.com
Vijay Shanker is an attorney in the Appellate Section of the Criminal Division at the United States Department of Justice. He has briefed and argued several dozen criminal appeals, including three en bancs, in ten different federal circuit courts and prepares draft briefs for the Solicitor General for filing in the Supreme Court. He has briefed criminal issues ranging from Fourth Amendment search and seizure to sentencing to criminal forfeiture. Vijay has received six Justice Department Special Achievement Awards for "sustained superior performance of duty."
Vijay received his B.A. in Public Policy Studies, cum laude, from Duke University in 1994. He received his law degree in 1999 from the University of Virginia School of Law, where he was named to the Order of the Coif and was awarded the Roger & Madeleine Traynor Prize and the Law School Alumni Association Best Note Award. He served as a Notes Editor on the Virginia Law Review and also published a note, "Alcohol Direct Shipment Laws, the Commerce Clause, and the Twenty-First Amendment."
After graduating from law school, Vijay served as a law clerk for the Honorable Chester J. Straub on the United States Court of Appeals for the Second Circuit in New York. Following his clerkship, he practiced general civil, white-collar criminal, and appellate litigation, first at Covington & Burling and then at Mayer Brown. He joined the Justice Department in 2005.
Currently Teaching
There are no classes currently associated with this professor.
Degrees & Universities
- J.D., University of Virginia School of Law 1999 (Order of the Coif)
- B.A., Duke University 1994 (cum laude)
Selected Publications
- Vijay Shanker, Note, Alcohol Direct Shipment Laws, the Commerce Clause, and the Twenty-First Amendment, 85 Va. L. Rev. 353 (Mar. 1999).


text:
Do you think about money a lot these days? Worried about whether you'll have enough cash to retire on time — or ever? Afraid of what will happen to your family if an emergency strikes, since you don't have enough of a cushion in your bank account?
You're not alone. American savings are desperately low right now.
Much of the mayhem that has been wreaked on U.S. savings is attributed to the financial crisis. But some of the fallout is self-inflicted as 401k investors and older American workers get dangerous and sometimes desperate with their nest eggs.
Here's some of the trouble that's going on:
Loans of Last Resort
If you have a decent nest egg, you can take loan out of your 401k at a reasonable interest rate and with minimal penalties. But if you fail to repay that loan, it's as good as an early withdrawal and subject to a 10% haircut.
The motivation for this kind of 401k depletion is clear: desperation. Families tap their nest egg to get through a rough patch — such as the loss of a job or an ARM adjusting up its interest rate — but never get their heads back above water in time to repay the loan.
If you think this kind of behavior was only a function of the 2008-09 downturn, think again. According to a stark report by the Brookings Institution and Navigant Economics, many Americans still are borrowing against their 401k plans, and many are failing to pay the cash back and being hit with the penalties.
Defaults are sucking out up to $37 billion annually, and researchers project the default rate between July 2011 and May 2012 was 17.4% — down from a peak of 19.8% during the depths of the financial crisis, but an ugly number all the same. Before the recession, default figures were half that at under 10% for summer 2008.
Day Trading Retirement Funds
Of course, some older Americans aren't immediately feeling the burn. They can keep the lights on with their current situation … though admittedly, retirement seems wholly out of reach.
The result is increased risk-taking among this group as they try to make up for lost time (and money). A recent report from Aon Hewitt shows the average 60-year-old has only $114,500 in his or her 401k — which is a measly $4,580 annually if you plan on living another 25 years. But the scary part is that half have less than $37,300 in total.
The result is, in a word, panic. Older workers will try just about anything to juice returns, even if it's risky.
In a recent Los Angeles Times article, Jeff Fischer at The Motley Fool said as many as 40% of people trading options at the site do so in retirement accounts like 401k or IRA plans.
"There is — I don't want to use the word 'desperation' — but it's close to that," Fischer told the Times. "Ten years of a flat stock market bumps up against reality for people in their 50s or 60s who are running out of time to see appreciation."
Smart investment decisions, of course, will grow your money faster. The risk is very real.
Lower Savings Rates
Click to Enlarge In the depths of the recession, many employers cut their 401k match plan and many employees rolled back their savings rates. After all, the need to survive was much more important than a need to plan long-term — and that goes for both businesses and workers alike.
But while things have improved across the board, roughly a quarter of companies aren't as generous with their retirement benefits.
A November 2011 report from business consultant Towers Watson shows that 75% of the 260 companies they surveyed have restored their retirement benefits to the same level, but 23% aren't offering as rich a package.
Many employees have been making up the difference by stowing more cash in their 401k funds in recent months as some measure of stability has returned to Wall Street and the broader economy (at least compared with the financial crisis). But it's clear they are choosing retirement planning above any other form of savings.
39% of percent of people surveyed by the National Foundation for Credit Counseling said recently that they carry a credit-card balance over from month to month. That's down only a tiny bit from the 44% peak in 2009.
A survey from Sun Life Financial shows that only a quarter of working Americans are "very confident" that they will have enough money for basic living expenses in retirement, down from 42% last year.
Oh yeah, and general savings have gone down the tubes. According to Bankrate.com, Almost half of Americans say they don't have a rainy-day fund that will last them three months of expenses if tragedy strikes in the form of illness, joblessness or other harsh events. More disturbing is that one in four don't have a penny in emergency savings at all.
What to Do?
The million-dollar question Americans have right now is what to do with their money to stay safe and hopefully provide for retirement. Well, here are a few tips — presuming you have the means to be proactive and aren't stuck in an unfortunate situation where you simply don't have the income to pay the bills, let alone save.
- Don't panic: Money matters are stressful, but if you are gainfully employed and have a sustainable budget, there is no reason to flip out. The most important thing is that, unlike some less-fortunate Americans, you are financially solvent. Take comfort in this instead of freaking out about the flaws in your budget.
- Build up a rainy-day fund first: If your daily budget is sound, start building a rainy-day fund and have the discipline to leave it alone. Start shuffling a few hundred dollars a month into a savings account that is liquid and at your disposal for emergencies. Don't spend a dime of your tax return in April, and instead plow it into savings. Give your spouse a "birthday present" of savings. It will take time — maybe a year or two — but is crucial to your financial health. Otherwise, one car breakdown or medical issue could ruin any other plans you have.
- De-leverage high-interest rate debt if you can: If you have rainy-day funds, then start taking care of your debts by prioritizing interest rates. An auto loan at 3% or less is basically just pacing inflation — so focus on that credit card balance charging 15% instead. Even an extra $20 or $50 in principle each month can dramatically whittle down balances over time.
- Put money to work, even modestly: If you have relatively low debt and an emergency fund, now it's time to put your money to work. Contribute the full 6% allowed by tax law into your 401k, or consider opening up an IRA. If the markets scare you, then at the very least consider a CD, even a short-term one, which can offer you significantly higher interest than a retail bank's savings account.
- Take the long view: Big financial decisions are not about picking the right number on the roulette wheel for one spin, but about a long-term commitment to your goals. Plot a clear course and revisit it regularly, but have the patience and discipline to see things through. It might seem pointless to save a mere $200 a month here and there or to contribute a mere $2,000 a year to a 401k plan. But if there were easy ways to amass the money you need and deserve, you would be golfing right now instead of surfing the Web for tips. Keep the long term in mind.


text:
Olivea says farewell with a dinner deal tonight
It's the last day of service at Olivea, 719 East 17th Avenue. Owners/husband-and-wife Stephanie Bonin and Keith Arnold have decided to pursue personal plans back East.
See also: -Olivea, one of Denver's top restaurants, is closing in mid-January -First impressions of Olivea -A conversation with John Broening, of Duo and Olivea
The Mediterranean-inspired restaurant is offering a special, three-course menu for $25 as a parting gift to its patrons, and while most of the reservations are sold out, there are still a few seats available after 9:30 p.m.
Olivea opens at 5 p.m. this evening for the last time; call 303-861-5050 for more information.
For information on dozens of culinary events around town, visit our online Food & Drink listings -- and if you have information for a culinary event you'd like included in our online calendar, send it to firstname.lastname@example.com.
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Denver, CO 80203
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text:
"Patterns of the Soul" Review
First Published: 07/08/99
"Patterns of the Soul" is a solid episode if you overlook its several flaws. The most important feature is that we finally get to see Marjean Holden's character, Dr. Chambers.
The Excalibur is rerouted by an Earth Force general to investigate a group of colonists who left Earth during the Drakh attack and may be infected. Gideon's mission is complicated by two factors: the presence of a second group on the planet who may have been infected by the colonists and suspicions that the general may not be telling Gideon the whole truth about his motives for taking the colonists into custody.
Dr. Chambers plays a large role in this episode since she must diagnose whether the colonists are infected. Marjean Holden turns in a performance which, while not spectacular, is acceptable for someone so new to the character. Carrie Dobro is settling into Dureena's shoes well, portraying sincere emotion when she makes her shocking discovery.
It is refreshing that instead of finding a convoluted Catch-22 type solution to the problem, Captain Gideon takes the simplest approach, which turns out to be effective and makes perfect sense. However, we must wonder if the general will check up on Gideon's story.
On the down side, this episode has several problems. First, why is the Excalibur selected for this mission? The general should have selected a captain he could trust more, even if the order truthfully came from President Sheridan. Second, the blood test to determine infection takes several hours, but the doctor is seen later using a handheld device that beeps when it is near contaminated food. Third, Gideon transmits the communication with the escaping ship to the general. Dr. Chambers is clearly seen in the background. When she turns up alive, the general will know he's been tricked.
The most unforgivable flaw is the nano-shield. Please, Joe, this is just too Star Trek. Did this really get past the science advisors at JPL? Obviously the purpose is to not hide the actors behind breathing masks, but surely there is a better solution. This technology could be abused too easily in future episodes and also reduces the apparent danger of the plague.
Good performances from the two leaders of the renegade colonists help to overshadow this episode's flaws, setting it firmly in the middle of the five episodes shown to date.


text:
After just recovering from an emergency appendectomy, Bret Michaels was rushed to the hospital last night after experiencing severe headaches. Turns out he suffered a brain hemorrhage and is now listed in critical condition. TMZ reports:
According to Cedars-Sinai Medical Center, people who don't receive proper medical treatment after suffering a subarachnoid hemorrhage have a 20% to 30% chance of experiencing a second bleed within the first month — and the odds of surviving a second bleed are extremely slim.
Cedars states, "Recurrent bleeding has a 70% mortality rate."
Fortunately, Michaels is reportedly being treated in a capable medical center.
However, it appears as though Michaels is already beating the odds — Cedars reports that roughly 1/3 of people who have a subarachnoid hemorrhage die during the hemorrhage because of extensive brain damage. Obviously, Michaels has already cleared that hurdle.
As a show of support for Bret Michaels, The Superficial Writer will bang twice the normal amount of strippers tonight which will put me at a whopping 0.5 in one evening.
I should probably stretch.
UPDATE: Bret's dad says he's "doing good" and resting which is great because I can't keep sexually satisfying all these groupies. Or even one. The clitoris is a myth!


text:
average rating: -- / 10
Jeune psy parisienne, n'ayant pas beaucoup de temps pour cuisiner... sauf le we!
City: 75020 paris
Ratings given by this member
This member has not given a rating yet.
I wanna cook
Cooking something?
Whatever it is, sell a few portions on Super Marmite! It's a great way to interact with your local community and to get real feedback on your cuisine :)Post a meal


text:
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100 kick-ass comments100 of your comments are neither buried or moderated. Popular is your middle name!9%
Keen reader – Level: godlike ninjaYou have voted for 100% of the entire collection of FMLs to date.23%
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The return of the thumbYou have thumbed 5000 comments.0%
The thumb strikes backYou have left your thumbprint on 2500 comments.0%
MobilityYou are connected to FML via the mobile site or an app. How modern.17,600%
Up and coming moderatorIt's nice of you to help us sort out the submissions, using FML's moderate feature.17,100%
I agree, my mouse works.200 "I agree" votes is a good start.3,159%
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JudgmentalYou have voted "You deserved it" over 100 times.68%
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Today, my son drew in Sharpie all over the wall, so I spanked him as punishment. When my boss came over for dinner, my son shouted, "Daddy made me take my punishment in the butt." FML
By ohcrap / Tuesday 2 August 2011 04:58 / United States
Today, after I successfully blew up a really large balloon, my mom said, in front of my older brother's friends, "Wow, you're going to make some man really happy one day!" FML
By e_edge - / Sunday 5 June 2011 06:48 / United States
Today, my "friend" put itching powder in my cast while I was sleeping. FML
By scratchy / Tuesday 8 February 2011 21:39 /
Today, I was walking with and hugging my girlfriend at the same time. I tried to be funny and touched her breast, saying "Boob" in a silly voice. In reply, she slapped me in the crotch, saying "Dick" in the same voice. FML
By Anonymous - / Sunday 21 November 2010 08:01 / Mexico


text:
JACKSON — The University Research Center recently updated the online data resource, the Mississippi Handbook of Selected Data, which contains maps, graphs and tables displaying socio-economic data relevant for Mississippi.
Last updated in 2002, the handbook is published exclusively on the web and features an interactive table of contents for ease of navigating through the publication.
"The Mississippi Handbook of Selected Data has always been a valuable resource," said Dr. Darrin Webb, state economist and director of the University Research Center. "The new interactive table of contents makes it more accessible, while the real time updating keeps the data current. We encourage users to send us their comments and suggestions for making this even more useful."
Rather than periodically publishing a single document, the new Mississippi Handbook of Selected Data will be updated on a continuous basis, with each page being updated as new data become available. An icon on each page allows users to send an email to notify the University Research Center when new data are available. Users can also use this icon to direct questions or comments to URC staff members.
The Mississippi Handbook of Selected Data is posted on the University Research Center website at www.mississippi.edu/urc. Users can also access other URC publications at this site such as Mississippi's Business, The Mississippi Outlook, and Economic Trends.


text:
Is it possible that you are not aware that you are the King of Pannonia?
It came up, he says, from Hungary and Pannonia and extended to Britain.
The part next to Gaul is wetter, and that next to Pannonia and Noricum higher and more windy.
During that time the news we received from Pannonia was far from being satisfactory.
Presently they were in possession of Pannonia, the empty nest of the Vandals.
Mad, indeed, had I been not to have looked for him in the ranks of Pannonia's army.
They now entered into relations with the Empire, and were settled on lands in Pannonia.
A message must be sent to Bertram telling him to return to Pannonia at once.
The inscription recorded that it had been erected by Pusinna to the memory of her husband Dagvaldus, a soldier of Pannonia.
Unfortunately for his own schemes, he fell ill in Pannonia, en route to Zaarfburg.
ancient name of the region roughly corresponding to modern Hungary.


text:
Get an overview of this hotelMotel in LaPlace with 24-hour front desk
Popular property highlights
Situated in LaPlace, this motel is 10.8 mi (17.4 km) from Destrehan Plantation and within 20 mi (32 km) of Susan Park and Esplanade Mall. Zephyr Field and Pontchartrain Center are also within 20 mi (32 km).
Property Features
A 24-hour front desk and free WiFi in public areas are available at this motel.
Room Amenities
All 28 rooms offer TVs with cable channels and conveniences like refrigerators and microwaves. Free local calls and showers are also available to guests.
Guest Highlights
- Clean guestrooms
LaPlace Motel
Hotel Amenities
Hotel Amenities
Public areas are equipped with complimentary wireless Internet access.
- 24-hour front desk
- Total number of rooms - 28
- Number of floors - 2
- Free WiFi
Family Friendly Amenities
- Free Wi-Fi
- Refrigerator
- Microwave
Available in some public areas: Free WiFi
Room Amenities
- Air conditioning
- Free local calls
- Microwave
- Refrigerator
- Private bathroom
- Shower only
- Television
- Cable TV service
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
- In-room accessibility
Hotel Policies
Check-in time starts at 3 PM
Minimum check-in age is 18
Check-out time is 10:30 AM
Payment types
Children and extra beds
- Children are welcome.
- Rollaway/extra beds are not available.
- Cribs (infant beds) are not available.
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on property policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
No rollaway/extra beds available
No cribs (infant beds) available
Hotel Name
- LaPlace Motel


text:
optic atrophy type 1
Optic atrophy type 1 is a condition that affects vision. Individuals with this condition have progressive vision loss that typically begins within the first decade of life. The severity of the vision loss varies widely among affected people, even among members of the same family. People with this condition can range from having nearly normal vision to complete blindness. The vision loss usually progresses slowly.
People with optic atrophy type 1 frequently have problems with color vision that make it difficult or impossible to distinguish between shades of blue and green. Other vision problems associated with this condition include a progressive narrowing of the field of vision (tunnel vision) and an abnormally pale appearance (pallor) of the nerve that relays visual information from the eye to the brain (optic nerve). Optic nerve pallor can be detected during an eye examination.
Optic atrophy type 1 is estimated to affect 1 in 50,000 people worldwide. This condition is more common in Denmark, where it affects approximately 1 in 10,000 people.
Optic atrophy type 1 is caused by mutations in the OPA1 gene. The protein produced from this gene is made in many types of cells and tissues throughout the body. The OPA1 protein is found inside mitochondria, which are the energy-producing centers of cells. The OPA1 protein plays a key role in the organization of the shape and structure of the mitochondria and in the self-destruction of cells (apoptosis). The OPA1 protein is also involved in a process called oxidative phosphorylation, from which cells derive much of their energy. Additionally, the protein plays a role in the maintenance of the small amount of DNA within mitochondria, called mitochondrial DNA (mtDNA).
Mutations in the OPA1 gene lead to overall dysfunction of mitochondria. The structure of the mitochondria become disorganized and cells are more susceptible to self-destruction. OPA1 gene mutations lead to mitochondria with reduced energy-producing capabilities. The maintenance of mtDNA is also sometimes impaired, resulting in mtDNA mutations.
The vision problems experienced by people with optic atrophy type 1 are due to mitochondrial dysfunction, leading to the breakdown of structures that transmit visual information from the eyes to the brain. Affected individuals first experience a progressive loss of nerve cells within the retina, called retinal ganglion cells. The loss of these cells is followed by the degeneration (atrophy) of the optic nerve. The optic nerve is partly made up of specialized extensions of retinal ganglion cells called axons; when the retinal ganglion cells die, the optic nerve cannot transmit visual information to the brain normally.
It is unclear why the OPA1 gene mutations that cause optic atrophy type 1 only affect the eyes. Retinal ganglion cells have many mitochondria and especially high energy requirements, which researchers believe may make them particularly vulnerable to mitochondrial dysfunction and decreases in energy production.
Some individuals with optic atrophy type 1 do not have identified mutations in the OPA1 gene. In these cases, the cause of the condition is unknown.
This condition is inherited in an autosomal dominant pattern, which means one copy of the altered gene in each cell is sufficient to cause the disorder.
- autosomal dominant optic atrophy
- autosomal dominant optic atrophy Kjer type
- dominant optic atrophy
- Kjer type optic atrophy
- Kjer's optic atrophy
- optic atrophy, autosomal dominant
- optic atrophy, hereditary, autosomal dominant
- optic atrophy, juvenile
- optic atrophy, Kjer type
- Centers for Disease Control and Prevention: Vision Loss Fact Sheet (PDF)
- Cleveland Clinic: Color Blindness
- Cleveland Clinic: Coping with Vision Loss
- Cleveland Clinic: Optic Atrophy
- Disease InfoSearch: Optic atrophy 1
- Kids Health: What's Color Blindness?
- MalaCards: autosomal dominant optic atrophy, classic form
- Merck Manual Consumer Version: Overview of Optic Nerve Disorders
- Orphanet: Genetic optic atrophy
- The University of Michigan Kellogg Eye Center: Optic Atrophy
- Washington University, St. Louis: Neuromuscular Disease Center
- Amati-Bonneau P, Milea D, Bonneau D, Chevrollier A, Ferré M, Guillet V, Gueguen N, Loiseau D, de Crescenzo MA, Verny C, Procaccio V, Lenaers G, Reynier P. OPA1-associated disorders: phenotypes and pathophysiology. Int J Biochem Cell Biol. 2009 Oct;41(10):1855-65. doi: 10.1016/j.biocel.2009.04.012. Epub 2009 Apr 21. Review.
- Cohn AC, Toomes C, Hewitt AW, Kearns LS, Inglehearn CF, Craig JE, Mackey DA. The natural history of OPA1-related autosomal dominant optic atrophy. Br J Ophthalmol. 2008 Oct;92(10):1333-6. doi: 10.1136/bjo.2007.134726. Epub 2008 Jul 24.
- Ferré M, Bonneau D, Milea D, Chevrollier A, Verny C, Dollfus H, Ayuso C, Defoort S, Vignal C, Zanlonghi X, Charlin JF, Kaplan J, Odent S, Hamel CP, Procaccio V, Reynier P, Amati-Bonneau P. Molecular screening of 980 cases of suspected hereditary optic neuropathy with a report on 77 novel OPA1 mutations. Hum Mutat. 2009 Jul;30(7):E692-705. doi: 10.1002/humu.21025.
- Fuhrmann N, Alavi MV, Bitoun P, Woernle S, Auburger G, Leo-Kottler B, Yu-Wai-Man P, Chinnery P, Wissinger B. Genomic rearrangements in OPA1 are frequent in patients with autosomal dominant optic atrophy. J Med Genet. 2009 Feb;46(2):136-44. doi: 10.1136/jmg.2008.062570.
- Zanna C, Ghelli A, Porcelli AM, Karbowski M, Youle RJ, Schimpf S, Wissinger B, Pinti M, Cossarizza A, Vidoni S, Valentino ML, Rugolo M, Carelli V. OPA1 mutations associated with dominant optic atrophy impair oxidative phosphorylation and mitochondrial fusion. Brain. 2008 Feb;131(Pt 2):352-67. doi: 10.1093/brain/awm335.


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New York Yankees' center fielder Curtis Granderson decided to see in person what had happened in the aftermath of Hurricane Sandy. Granderson went to Staten Island to get a first hand look of one community rocked by the super storm.
"It just lets you know what things are really important," he said of his trip to Staten Island as reported by MLB.com. "The home you've worked your whole life for — family, friends, food, hot water. The bare necessities are really all you need. Everything else is luxury. That community over there is experiencing that. They're still very positive. They're very optimistic. They're going to come back. They're going to come back stronger than ever. If you've ever had a broken bone, you know it heals stronger than what it was."
Granderson's The Grand Kids Foundation wanted to help families who were ravaged by Hurricane Sandy, so Curtis in along with PricewaterhouseCoopers donated 2,000 backpacks to local children.
Curtis while in Staten Island visited local PS 39 to interact with students and see how they were coping with what had happened in their lives and help distribute school supplies. He also spoke to residents and saw how they were cleaning up and trying to get their lives back to normal.
"You see photos, video and you hear stories about different devastated areas, but until you get a chance to go out there and witness it first-hand, words can't do it justice to see a house that was barely touched next to a house that's completely gone," he said. "The community's out there helping out with help centers where you can get water and a hot meal. Generators are coming into the area, and you've got the police there. You've got different people helping out. And then the community, hearing their stories about how a lady had to swim out of her house because she didn't evacuate in time. Families having to run up to the top roof. Families that all they can say is, 'I used to live here. My house isn't here anymore.' But they're all coming back, and whatever issues you had before you put it aside."
The Grand Kids foundation was started in 2007 and has raised more than $80,000 to help the education of our youth. PWC has themselves made a $160 million investment in teaching financial literacy in schools throughout the country and also include more than 37,000 of community service by their employees.
Besides Staten Island students in Coney Island, the Rockaways and Sheepshead Bay will benefit from the foundation and program.
Tags: Baseball, Curtis Granderson, Hurricane Sandy, MLB, New York, New York Yankees, Staten Island, The Grand Kids Foundation


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France, the US and other countries are showing little confidence in the week-old ceasefire in Syria and are increasing the pressure on President
Fifty-seven countries, meeting in France, voted to tighten sanctions on Syria as Russia accused Persian Gulf nations of arming opposition fighters. Members of the so-called Friends of Syria group are openly supporting the rebels with non-lethal assistance, such as communications equipment, and weighing gestures to further cast Mr Assad's regime as a pariah, including the expulsion of Syria's ambassadors, according to European diplomats who are not authorised to speak to the media.
Although the daily death toll has dropped, Mr Assad has not lived up to the terms of the UN-backed peace plan, which include a pullback of his forces and steps toward democratic reforms. Even as the first UN monitors arrived in Syria, Mr Assad's tanks continued attacking Homs and other areas, US State Department spokesman Mark Toner said.
Joshua Landis, director of the Centre for Middle East Studies at the University of Oklahoma at Norman, said: "The long-term prospects of ceasefire are not good, primarily because it addresses none of the underlying issues." Furthermore, some countries wanted only one outcome – the end of the Assad regime.
The Sunni Muslim Gulf countries want to weaken Shiite Muslim Iran by ousting its closest regional ally, Mr Assad. "They don't think dialogue is possible, and anything that falls short of replacing the regime is a defeat," Mr Landis said.
Qatar's Prime Minister, Sheikh Hamad Bin Jasim Bin Al Thani, entering an Arab League meeting with UN special envoy
"Nothing has changed for me personally in the situation as I see it," he told journalists in Qatar.
A UN diplomat said the widespread view was that although there was little chance the ceasefire would work, it offered an opportunity to deploy observers in the country. The ceasefire monitors, if deployed, would be in a position to assess the military actions of Mr Assad's forces and the armed opposition, as well as to document possible war crimes by the regime.
Six UN monitors, led by Moroccan Army colonel Ahmed Himmiche, have arrived in Syria. Another 25 to 30 observers were expected to follow in the next few days, Mr Toner said.
In Paris, the Friends of Syria held a meeting to consider ways to increase financial pressure on the Syrian leadership. Officials represented the European Union, the Arab world, the US and other nations sympathetic to the anti-Assad movement.
French Foreign Minister
Russia and China have blocked efforts at the United Nations to punish Syria for its crackdown. Still, individual countries have frozen Syrian assets and barred regime officials from visiting. The Paris meeting participants discussed freezing individuals' assets, as well, one of the European diplomats said.
Other efforts include the U.S. equipping opposition forces with communications gear, a Gulf-funded plan to pay salaries to opposition fighters and coaching by several countries, including the U.S., to help the fractious opposition groups become a more cohesive force, the diplomats said.
Onus on Assad
Russian Foreign Minister Sergei Lavrov said yesterday on state television that "outside forces" continue to give the opposition arms and encouragement in order to undermine the cease-fire.
In Syria, government forces killed 39 people yesterday, mainly in the northern province of Idlib, the Local Coordination Committees in Syria reported on its website.
The "erosion" of the cease-fire is unacceptable, Toner said yesterday in Washington. Noting that the opposition has "has held its fire and lived up to its side of the agreement," Toner said that "the onus is on the Assad regime" to comply with the UN peace plan. In Annan's six-point plan, Assad committed to undertake a Syrian-led political process, cease all violence, provide humanitarian assistance, release detained prisoners, allow journalists to move freely and respect Syrians' right to demonstrate peacefully.
"They've barely fulfilled one," Toner said.
'Last Best Efforts'
Landis said the Assad regime may benefit if the cease-fire prevents the issue from reaching the Security Council and enables Syria to pressure the West to limit support for the opposition. "In many ways, this plays into regime hands," Landis said.
The U.S. ambassador to the UN, Susan Rice, said that wasn't so. The monitors "are perhaps the best, and potentially the last best, efforts to resolve this situation through peaceful diplomatic means," Rice said yesterday in New York.
"It may be impossible to do so," she added, if the regime insists on continuing to use violence "as long as it can get away with it."
The tenuous cease-fire may give the opposition time to regroup and enable the Syrian Free Army to improve its command and control, Landis said. "They've taken an incredible beating from the regime," he said. "They're fragmenting, bickering, falling apart."
The opposition can't wait too long before it starts testing the cease-fire, Landis said. "The longer they take to get organized, the more distracted the international community will get," he said. "A lot of things can come up to steal the fire of the Syrian Revolution."
--With assistance f
Bloomberg , Bloomberg


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after running e2fsck -v -y /dev/hda2 it says segmentation fault then goes back to konsole but it says (none)#_____ any ideas how to fix this?
ok i finally got BT loaded on to laptop but its still saying i need to run 2fsck -v -y dev/hda2 or something ive done it 5 time and it wont do anything else, is says sign in as user by typing control-d or use root pw to perform maintence well ive done the maintenance it didnt really help at all so i tried to log in by typing "control-d", holding control and d i dont know i must be retarded how do i log in?
after running e2fsck -v -y /dev/hda2 it says segmentation fault then goes back to konsole but it says (none)#_____ any ideas how to fix this?
After you hit ctrl-d it should drop you to a login prompt.
Make sure you video tape it and put it on YouTube.going to smash computer
when i hit control-d it reboots everything and tells me the same thing "manually run 2xfsck on hda2"...."log into user account by typing control-d"..."or enter root password to enter maintenenace". i dont know what else to do i reformated that partition in windows and using Gnome partition and changed file system to ext2 and it still says it
Sounds like you have a harddrive with physical bad sectors.
Might be time to buy a new one.
A third party security audit is the IT equivalent of a colonoscopy. It's long, intrusive, very uncomfortable, and when it's done, you'll have seen things you really didn't want to see, and you'll never forget that you've had one.
Test your Hard Drive if its still good with a DFT test (Drive Fitness Test)
Download this program at this site
This will create a bootable floppy disk. A CD image is also available for download
then just run the floppy or cd which ever one you make and do advanced test on your hard drive
If it passes you'll get a green screen, that mean your hard drive is fine
If you get a red screen it means you have a bad hard drive and show what section is bad.


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I spend a lot of time fighting Islamaphobia. I want to stress at the start of this article that it is not about Islam. It is, however, about those employing Islam as a tool to grab and hold power. To me the psychology and motives of The Muslim Brotherhood and other Islamic politicians are the same as those represented by the political Christian Right in America who just lost in the last election. It is a great temporary benefit to be be able to say to unsophisticatedand often illiterate people, "Vote against me or disagree with me, and you are disagreeing with God." The problems come once the election is won, and the people see that you are employing the same tactics as the regime you were to replace and working to fit the facts and religion to support your position. To the simple people, it will God who let them down.
There was a recent article in the Egypt Independent (www.egyptindependent.com) which I seeded that discussed this subject. The article, along with another on the changes taking place in Egyptian thinking since the revolution, have given me new hope that the revolutionaries who marched into Tahir Square may be victorius yet. I have discussed matters of faith with Egyptians who have put their religion "on hold" and who are questioning those they once felt should never be questioned. The Imams in the mosques are no longer trusted to be good, honest men. More and more they are seen as politicians seeking power to control others and to force others to observe their brand of Islam.
I was very surprised when I asked Egyptians why the Salafi were making such a big deal out of allowing girls to marry at 10 and were opposed to articles against human trafficking (slavery). It was explained to me that many rich Salafi are engaged in the arrangement of child brides (short term marriages) to rich pedophiles in Saudi Arabia and the Emirates. This is but one example of behavior that is making many Egyptians put their religion "on hold" and to question the motives of those professing to be "protectors of the faith." Most in Egypt know Islam is not about growing a beard or wearing a veil. Often when these issues are discussed, I see a twisting of the wrist which means,"What is this?"
The Brotherhood is seen as people after power only; the only relationship they are seen to have with Islam is the word "Muslim" in their name. They are acting just like Mubarak. Mubarak used guns to control the people; The Brotherhood wants to use God. The President of ALL Egyptians is so addicted to this "Islamic cause" that he could not bring himself to attend the coronation of the Copt's new pope. I heard more comments about this from Muslims than I did from Christians. His actions did not reflect the spirit nor the goals of those who faced death in Tahir Square. The Brotherhood wants the people to fear God and consequently them. They forget Rumi's "Those who thirst and fill a cup with water will see God's face in it, but those who do not LOVE God will see only their faces" The members of The Brotherhood are mistaking the reflections of their faces for that of God.
It is a shame The Muslim Brotherhood and President Morsy have chosen the course they have. They could have done a lot to help Islam and democracy in Egypt. The first step they should take is to remove ALL references in the new Constitution that restrict religious freedom in any way. The same with all articles that limit other freedoms. Let then lead by example. Let them provide freedom for the people, end corruption, really listen to differing opinions, and involve the people of Egypt in building what should be the richest country in the Middle East. Let them discuss with the clerics in the mosques to talk about more than women as evil, sex, and how terrible everyone else is. The Egyptian people need a message of hope, of God's forgiveness (remember it is "God, the most merciful and all compassionate" - not God a nasty old man who wants to send everyone to Hell). In other words, it is time for The Muslim Brotherhood to prove the good of Islam by their example, not words. Let them encourage Muslims to help Christians rebuild or renovate churches that have been neglected. Let them encouarge "brotherhood" dialogues and speak out when Muslims are in the wrong.
All the time I have been in the Middle East, I have never heard an Arab say, "We were wrong." The Brotherhood could lead a national dialogue in Egypt about how Egypt needs to change, what are traditions and what is religion. You cannot have a revolution without self-examination and an open discussion of the future and how to get there.
The youth who went to Tahir Square brought out the best of Egypt. I hope they do not have to go to the streets again because old men want to play old games and hold on to old power. The Muslim Brotherhood now faces a choice, lead Egypt into true freedom for ALL Egyptians or play the old political games and pave the way for the next bloody revolution. Your true religion is how you lead your life - not how you try to force other to lead theirs.


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Patient police work and a clever piece of computer programming have helped convict a pedophile who preyed upon his own daughter.
The man, who cannot be identified to protect his young victim, was jailed for 6˝ years yesterday after a County Court jury convicted him last week of one count of incest and four counts of performing an indecent act with a child under 16.
Judge Graham Anderson said the man had filmed and photographed his daughter while she was naked, on several occasions between 2000 and 2002. She was 12 at the time of the first offence.
Judge Anderson said the man had initially denied any inappropriate contact after the girl told first her mother and then police of the abuse.
Police searched his home in August 2002 but were unable to find photographs or footage described by his daughter.
Instead, they found a large encrypted file on the man's computer hard drive that could be opened only with a password.
When the man refused to reveal the code, a police computer specialist set up a program to crack the password by cycling through endless combinations of letters.
"After 19 weeks of continuous operation that password was found and access gained to the file," Judge Anderson said.
Inside the file were 895 images and pieces of footage, mostly downloaded from internet child pornography sites.
That evidence persuaded the man to plead guilty to a charge of possessing child pornography and helped the jury convict him of five of the seven other charges, to which he had pleaded not guilty. He was found not guilty of one charge of committing an indecent act and one count of incest.
Judge Anderson said the man had shown no remorse. "During the course of the trial his daughter was branded as shifty and as a liar," he said.
The man will serve a minimum sentence of 3˝ years.
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Maybe Accepting Guests
- Last login over 1 year ago
Join Couchsurfing to see Marion's full profile. It's free!
About Me
Meet lots of people all around the world
I'm a generous person who like having a good time with my friends, making party or just have a drink and talk. I like having friends dinners.
Enjoy the life and having fun is one thing very important for me!!!
Don't worry be happy!!!
Happy Days! Positive attitude ;D
Croque la vie a pleine dents, on ne vit qu'une fois alors profite a fond du moment présent!!!
Why I'm on Couchsurfing
For the moment I can't host people but, It will be a pleasure to take a drink or show you around my wonderful town!!!
I had one CS experience in New Zealand at Gisborne, it was very good experience, my host were very friendly!!!
I love dancing, listening all kind of music, discover new city by walk and trying typicals foods, more and more things.
- culture
- dancing
- cooking
- partying
- drinking
- traveling
- music
Music, Movies, and Books
Films: Requiem for a dream, le dernier jour du reste de ta vie...
One Amazing Thing I've Done
Studding in Scotland my first travel experience, huge experience I had to find a flat by myself, studding, learning English, I could never forget this year.
Visiting New Zealand during 8 months, it was a wonderful year, I met a lots of people, very kind and Happy to share with you there culture!!!
Teach, Learn, Share
I can teach French.
I can share some cooking staff cause I love cooking!!!
Countries I've Visited
Belgium, Benin, Czech Republic, France, Germany, Italy, Netherlands, Spain, Togo, United Kingdom
Countries I've Lived In
France, New Zealand, United Kingdom


text:
The Real Reason For Gulf Oyster Decline and Other Top News From @slashfood For Aug. 5
What's Cooking at Slashfood
We love Slashfood so much that every Thursday we round up its most delicious stories. Here are this week's finds:
- The largest threat to Gulf oysters isn't BP's spill — it's an influx of freshwater.
- Martha Stewart talks about her upcoming TV show, Martha Bakes.
- Robert Sietsema discovers BK's new burger bar is a whopping disappointment.
- Sign of the times: McDonald's is preaching its locavore practices.
- Chatting with the latest exiled Next Food Network Star, Brad Sorenson.
- Luscious libations that are suitable for kids, and sophisticated to boot.
Image Source: Thinkstock


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On a winter day, the landscape at the Clearview ski resort is awash with white. So it's easy to spot near the foot of the mountain, a solid black shed of a cottage, its gabled roof offering just a hint of camouflage.
As the colour makes clear, this is an exceptional building, especially among the suburban log cabins in the neighbourhood. The boldly contemporary chalet is a getaway for a Toronto family, and they were willing to take a leap: They hired the young architecture and interior design firm Atelier Kastelic Buffey, and gave them carte blanche.
The result is a house that is, under its black-stained cedar façades, full of surprising decisions and details. Its inexpensive windows are framed with deep trim that makes them look substantial. The siding itself forms a nuanced pattern of slats and boards – horizontal in places, and vertical in others, forming lines that continue right up through soffits and gables to the top of the roof. "We're using a traditional language," explains architect Kelly Buffey, "but twisting it to create something more subtle and original."
Subtlety and originality are exactly the qualities that are getting AKB, led by Ms. Buffey and her husband, Rob Kastelic, noticed. Since meeting in the office of Kuwabara Payne McKenna Blumberg a decade ago, they've formed a partnership that has made them favourite architects for a very sophisticated set of art-loving, affluent Torontonians. They will be at the Interior Design Show this week showing off a small work – a revamped chair, for the Cherish charity auction. Having developed their unique aesthetic through bigger projects, from renovation jobs up to an 8,000-square-foot house and a church, they are ready for serious attention.
The Clearview house, one of four they've designed in Ontario ski country, demonstrates their finesse. Built on a restrained budget and intended almost exclusively for the winter season, it combines inexpensive materials with a bracingly clear aesthetic concept: Dark on the outside, light on the inside.
Through the front door is the foyer, a massive wet room geared for après-ski mess. A rubber-lined cabinet cradles ski gear; a large boot-warming machine, a wall of storage cubbies and a washer/dryer complete the amenities. Then you take a right turn into the kitchen and living room, and the house's aesthetic reveals itself clearly. Nearly every surface in sight is white, from the kitchen cabinetry (bought from Ikea) to the walls and window coverings. To the left, large windows show views of the countryside galloping away to the horizon. The floors are concrete, polished to a high sheen.
The interior was detailed by Ms. Buffey, who worked as an interior designer for about a decade with top firm Yabu Pushelberg as well as KPMB before she went back to school and studied architecture. In this house, she was able to largely express her favoured approach, a spare and careful minimalism. "The trouble with a minimalist or reductivist approach is that you can go too far, and it looks banal," Ms. Buffey says. "You have to introduce the right level of detail."
Here, that means a few graphic touches – including a Moooi pendant lamp that hangs gauzily over the dining table – and then a careful massaging of the building's structure and envelope. Ms. Buffey and Mr. Kastelic, who focuses more on structural and technical details, proportioned the house's inner spaces in unusual ways. For example: The living and dining area has a peaked ceiling that makes it feel expansive and barn-like. But where, in a barn, you can see the bones of the roof, here you're seeing an illusion. The ceiling is at a different angle from the roof above and it peaks in a different place, at the dead centre of the living room. This demanded some complex structural work, but Ms. Buffey believes it was worth it. "We'd rather spend money on things you might not notice, but that make you feel better without you knowing why they make you feel better."
That's a fine definition of the effect of fine architecture. And you will notice (or not notice) that quality throughout this house. Walk downstairs, past a very thick half-wall that lines the stairs and provides a sense of separation. Above, relatively tight eight-foot ceilings shelter you on your way to the lower level, which opens up to ground level at the back as the site slopes away. It is basically a dorm. The hall is lined with bedrooms – four of them, most with multiple beds – and two bathrooms, one of which is split into two separate rooms for shower and toilet. At the far end of the hall is a master suite, which can be hidden by a sliding door. Its washroom is visible at the end of the corridor, where its mirror creates shimmer and shadow at the furthest reaches of the view. It is a smart and tiny design move, which cost nothing.
Likewise, the bedrooms employ Ikea components rather than custom millwork. Wardrobe units are built into the walls, and small dressers (all white) are raised on platforms and built in as well. "I like how sensible that is," Ms. Buffey says of these purchases. "After all, the owners are not here all of the time." So, she implies, why be extravagant? It's an excellent question, and it reflects the intellectual rigour with which AKB does its work. Custom furniture would be unnecessary and, in an aesthetic sense, it would be wrong. This house, tough and wintry, is a perfect expression of its purpose. It asks: Why get fancy? Let's hit the slopes!Report Typo/Error
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Today's Devotional
Two SorrowsWhen have you sensed a heavy and consistent guilt?
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This course is designed to help you enter the furniture industry at many levels. It is suitable for both young people and mature students looking for a change in career. Successful candidates can enter the furniture industry as cabinet makers and wood machinists, or become self employed makers.
The focus of the course is to develop the practical woodworking skills necessary to produce high quality work, together with a good understanding of design and of the furniture industry.
· Health and Safety training – safe working practices
· Hand-tools techniques
· Machine woodworking – basic and advanced techniques
· Portable power tools techniques
· Traditional and modern cabinet making: joints, construction and fittings
· Materials technology: timber and timber based materials
· Technical drawing/CAD
· Veneering techniques
· Polishing and finishing techniques
· Furniture design and history of furniture
· Industrial studies
A range of related subjects
Yr 1 – City & Guilds 5780-01 - Level 1 Certificate in Furniture Making Yr 2 - City & Guilds 5780-22 - Level 2 Wood Machining DiplomaYr 2 - City & Guilds 5780-20 - Level 2 Diploma in Furniture Making
Assessment is via a portfolio of work produced during the course, timed assessment pieces question papers and short essays.
Fill in an application form and you will be invited in for an interview.
Minimum qualifications: Level 1
16-18 year olds: English & Maths at grade 4 or above
19+ years: an interest and a commitment to working with wood to produce high quality furniture
Applicants will be invited to attend an interview
As the course progresses from samples to complete pieces, there will be a charge for the cost of the materials of the items produced.
You can view more on our furniture YouTube channel
Furniture & Furnishings home page https://www.warwickshire.ac.uk/courses/subject_areas/art,_design_and_media/furniture_and_furnishings.aspx
English and Maths
English and maths qualifications are vitally important for future employers and universities, so the government has made it a priority for students to improve these skills.
Entry Level / Level 1 and Level 2: We're here to help you on your journey, so if you do not achieve grade A*-C in GCSE English and/or maths, then you will study English and/or maths as part of your college course.
Students who achieve a D grade will be placed on the relevant GCSE programme, while students who achieve an E or below will be assessed to ensure they are placed on the right study programme for their ability.
Level 3 programmes: You will need to meet the course entry requirements specified on the course information above. For the majority of our Level 3 courses, students will need grade A*-C in GCSE English and/or maths. If this is not specified in the course entry requirement, then you may be able to study English and/or maths as part of your college course.
On successful completion of this course you will be able to seek employment in the furniture industry as a cabinet maker, fitter or wood machinist and many other woodwork related careers. Alternatively, there will be opportunities to progress onto the Level 3 City & Guilds Furniture Design & Making course
Call: 0300 45 600 49 or email us now
Course tuition fees are free for UK students under 19 years, or students with an Education, Health and Care (EHC) plan and Local Authority funding.
All students may be charged for materials e.g. equipment, clothing etc.
UK students aged 19 and over will need to pay tuition fees as well as any materials, registration and exam fees. Some adults may be eligible for free tuition. Please contact us for more fee information.
We make every effort to ensure that these course details are accurate. Warwickshire College reserves the right to make alterations. Fees may be indicative at the time of publishing.