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It's not long to go now until the release of the new Sanguine Hum album 'What We Ask is Where We Begin'.
A look back at the beginnings of the 2012 prog award nominees 'What We Ask is Where We Begin' consists of an extended master of the original Joff Winks Band album 'Songs for Days' alongside a second disk of tracks rarities and unreleased compositions from the period.
If you haven't already seen the promo video, featured exclusively on Prog Magazines website in December 2015, then its time to whet your appetite!
"The entire album is genius"
John Deaux All About The Rock.co.uk
We were also thrilled to se that Sanguine Hum were voted number 88 in Prog Magazine's readers poll for "The 100 Greatest Artists of All Time"!


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Lush kozmetikler
İlgili konuları keşfedin
Skincare Update! // LUSH Cosmetics - Manifest Yourself
our massage bars - ready to go, and ready to make your skin glow!
Harbor East :: LUSH Fresh Handmade Cosmetics
pinterest- ❥@britttanym12❥
Ocean Salt Cleanser | Cleansers | LUSH Cosmetics | Read reviews great for people with large pores, oily and combo skin, and mild acne {ALL ME} Must try!!!
Pinterest: @DaniJennner
Ambition- be able to afford all this lush stuff - #crueltyfree&natural=expensive-but worthit.
Globe & Mail's Best texturizer: Lush Cosmetics Sea Spray, $12.95 at Lush (www.lush.ca).
Christmas Lush Haul 2016 | Sugar Plum Fairy Lip Scrub
Lush Rosy Cheeks Mask

subset: commoncrawl


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Healthy Vegan Oat and Pb Pancakes
Recipe by Megannnnnnnn
easy!! modified from ppk.
Top Review by Ransomed by Fire
I've eaten this a few times, and I really like it. I make it 1/3 at a time; so, my measurements aren't exact. And I use a whole packet of Splenda. I've used varying amounts of banana in it. Even when they don't work out for me (usually because my frying pans aren't very non-stick), worst case scenario, I eat it as a porridge type dish; and it's good then too. Thank you so much for a recipe that's helped spice up my breakfasts while I diet and that I'm about to eat, even though I've taken a week off from dieting. It's just that good!
See Discussion:1 Review
Ingredients Nutrition
- 1 1⁄2 cups oats
- 1 teaspoon baking powder
- 1⁄2 large banana
- 1 1⁄4 cups soymilk lite
- 3 tablespoons peanut butter, natural style
- 1 teaspoon stevia
- nonstick cooking spray
Directions See How It's Made
- Put oats in blender and blend until a flour is formed. Pour into a big bowl and combine with baking powder and stevia.
- In a seperate bowl, mash the banana and mix with the soy milk and peanut butter.
- Combine wet and dry ingredients. Mix well and let the batter set 5 minutes.
- Prepare as you would any vegan pancake! Grease a skillet and pour the batter out, cooking on both sides for about 2 minutes or so. Serve with maple syrup or even more peanut butter, if you like. I like to chop up a banana and serve over it.


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Erratum to: A review of recent research into aerodynamics of sport projectiles
- First Online:
DOI: 10.1007/s12283-013-0120-4
- Cite this article as:
- Goff, J.E. Sports Eng (2014) 17: 73. doi:10.1007/s12283-013-0120-4
1 Erratum to: Sports Eng DOI 10.1007/s12283-013-0117-z
In the original version, the buoyant force on a baseball has been incorrectly published as 1.5 % of the ball's weight (found between Eqs. (6) and (7)).
The correct buoyant force is 0.15 % of the ball's weight.
Copyright information
© International Sports Engineering Association 2013


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April 28, 2013
I'm a relatively new Python developer. I'm working on a web application using Django.
Well organized, very informative and useful.
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text:
posted by mark .
A soccer ball leaves the foot of a player with an intitial velocity of 22 m/s at an angle of 30 degrees above the positive x-axis.
After flying through the air, the ball lands with a velocity of m/s at an angle of degrees above the x-axis
the speed and angle on impact are the same as on takeoff. Just the direction has changed from up to down.


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We appreciate the many volunteers from our school and the whole community who came together to make Octoberama fun for all of us. Thank you for your commitment and your generous spirit!
Thanks to our Octoberama Committee
for all their hard work!
for all their hard work!
- Silent Auction: Amy Price and Tina Fernandez
- Grade Level Gift Baskets: Natasha Ulack
- Student Art Project: Emily Johnson,
Jennifer Binford & Carrie Heinley
- Games: Dani Willard and Adriana Morin
- Prizes: Tina Cannon
- Entertainment: Coby Ramirez
- Food: Marion Cimbala
- Volunteer Coordination: Elizabeth Breston
- Layout & Setup: Cisco Gamez
- Recycling: Germaine Curry
- PTA Treasurer: Ernest Rodriguez
Thanks to the community organizations
who volunteered time at our event!
who volunteered time at our event!
- UT Alpha Epsilon Delta (AED)
- UT Circle K International (CKI)
- UT Gamma Beta Phi (GBP)
- Masonic Lodge #12
- Dance Associates


text:
Skip to main content
Wilton Newcomers Club
Wilton, Connecticut
(Inc. 1802)
About WNC
Activities & Events
Join Us!
Wilton Links
Contact Us
Member Login
President's Letter
Welcome to The Wilton Newcomers Club!
Whether you are new to Wilton or have lived in this amazing community for some time, if you are interested in meeting new people we would love to meet you!
The motto of the Wilton Newcomers Club is friends, fun and community, and that is truly what we as an organization are all about. Throughout the year we offer a variety of social activities
including family events, ladies' and men's nights, cultural outings, couples dinners, game nights, morning coffees and much more. We
add activities to our calendar so please be sure to check it often.
In addition to all of our social activities, we pride ourselves in being a part of and giving back to our community. As an organization we have developed fundraising efforts throughout the year as a way to support our local social service organizations.
Please look through our website and join us! New friends and fun times are waiting for you! Feel free to contact us (
) if you have any questions or if you or your family would like to join us for one of our events prior to joining the club.
Warm regards,
Devon Rayment and Tammy Ward
WNC Co-Presidents 2016-2017


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About Me
My name is Kelsi, a.k.a. Koofie, and I invite you to join me and my family on our journey to learn about how our everyday choices impact our environment and what we can do to live more naturally. Natural living is not something that happens automatically; it is a process to change that requires a concerted effort to make eco-friendly choices in everything we do. We strive to do our part and help others learn to live a more natural lifestyle.
Koofie is the nickname given me by my brother as I was growing up. While still too young to correctly pronunciate my name, my baby brother came up with "Kesi" which somehow manifested into "Koofie" and eventually stuck. Only those that know me best call me Koofie – they are the people that have seen me migrate to a "greener," more eco-friendly lifestyle. Welcome to my inner circle, where I share all the things I learn to help others make less of an impact on the planet. You can learn from my trials and errors! Besides "greening" myself, I love gardening, reading, spending time with my family, and I'm even learning to like housekeeping and cooking.
I live in near Frederick Maryland on a farm, about an hour from where I grew up near Washington DC. My family is made up of myself, my two daughters, our Australian Shepherd, Rory, and our cats, Tigger and Titus. In "real life" I'm a homeschooling mom and flower farmer.
I love hearing from you so please leave a comment to any post that catches your eye or e-mail me!


text:
posted by Nicholas Lim .
Given g(x)=px+q where p and q are constants.If g^2(x)=16x+15 find the possible values of p and q?
I am confused by your data
if by g^2(x) you mean g(x)*g(x)
then it would be (px+q)^2
= p^2x^2 + 2pqx + q^2
but that was equal to 16x + 15
there was no x^2 term , so p=0
But that contradicts that 2pqx = 16x


text:
With Instructables you can share what you make with the world, and tap into an ever-growing community of creative experts.
Tell us about yourself!
pepper (curry) spray! survival against enemies
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Homemade Heating Pad
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Let your inbox help you discover our best projects, classes, and contests. Instructables will help you learn how to make anything!
© 2016 Autodesk, Inc.


text:
There are various techniques that can be used with your Pinion wood and most of them involve allowing your wood to burn slower and smoke more. With the pinion wood for sale, the sweet aromatic smoke is what you want to take advantage of. If you light it on fire and all it does is burn up, you have really lost the qualities of this fine gymnosperm that can repel bugs and mosquitoes in the summer and create a wonderful aroma during the Thanksgiving and Christmas season. If you are looking to buy pinion wood online we are a national distributor of this fine New Mexico firewood. It is a staple of the New Mexico resident and is known as the best choice for chiminea wood. Thanks for stopping by and let us know how we can serve you. There are many uses for pinion wood for sale - pinyon wood for sale - pinyon wood for sale for firepits and chimineas and even outdoor fireplaces and indoor fireplaces. Pinion wood has a high btu so it is great for heat for firewood for sale. Pinion wood at #growokc can supply your chiminea wood and pinyon wood - pinon wood - pinion wood needs year round. We ship our firewood straight to your door for the best convenience! Most people in the midwest and the on the east coast haven't smelled the aroma of pinion wood but may have vacationed in New Mexico. ow you can bring this smell to your own backyard!
GrowOKC is a Professsional Organic Horticulture Company. We have pinion wood, organic products, smoking wood pellets and cooking wood chips. #growokc
Hi Hank,
Yes, the smell of pinion wood does bring back some great memories if you were around it in your youth. If you need a semi of pinion wood you might want to try another state that has mass amount. If you need need homeowner amounts or a little more we'd be glad to help.
Let us know if you have any other pinion wood questions!
Yes, pinion wood reminds people of the festive time of the year because of the very unique smell. A lot of people have been to Santa Fe, New Mexico or Taos, New Mexico and smelled the air and they often ask what is that smell. It's the smell of pinion wood, often spelled pinyon wood or pinion wood being used in the wood stoves that the natives are using for heat or in their cook stoves. I've lived in New Mexico and if I'm away from the smell of pinion wood for sale, I miss it. Pinion wood lights easy and it has a pretty high BTU meaning the heat it puts off. It is also a long burning firewood for sale. Most people use it as chiminea wood, indoor fireplace firewood and outdoor fireplaces. When it comes to burning "green" pinion wood or seasoned pinion wood, I have done both. I don't see much of a difference in my tastes. I wish pinion wood was a smoking wood or cooking wood but it is not good for that because it is a gymnosperm tree and the sap is not swell for cooking. In the summer times of the year, bugs and mosquitoes do not like the smell of pinion wood so it makes a great natural insect repellant.
Thanks for your question!
Let me know if you need further help,
I have fond memories of going to new mexico as a child and smelling the pinion wood smell in the air. Glad to see someone selling it. Do you sell semi loads of pinion wood? Thanks
Hi Jack,
Our pinion wood for sale is great for chiminea wood fires, outdoor fireplaces and often used as a indoor heating wood fuel source. This pinion wood coming from New Mexico is used in all these fashions. The only way a pinion wood is not used is in cooking and smoking meat. Since pinion wood is a gymnosperm it has sap that doesn't work well in smoking meat and foods like hickory wood, pecan wood and oak wood for sale. Pinion wood also repels bugs and mosquitoes because they do not like the smell of it which is great. If you are looking for a smoking wood then some of our other smokig woods for sale at www.growokc.com will work a lot better. But for a campfire or campfire wood and roasting marshmallows, pinion wood has one of the most fabulous smells in the nation. Thanks for your pinion wood question!
Pinion wood is a great smelling firewood that makes it special to the Southwest. It is also spelled pinyon wood and pinon wood. The thing we do at #growokc firewood for sale is mix it with some other really nice smelling firewood. Mixing pinion wood for sale with hickory wood helps the fire burn longer and really gives it a unique firepit or outdoor fireplace smell. This also is great for a chiminea wood. Hickory has a unique smell and is our southern hickory wood for sale. Hickory firewood is used in cooking and as a smoking wood because of its unique southern smell. We can also mix our pinion wood for sale with pecan wood. Pecan wood is also a smoking wood and provides a unique smell for your outdoor chiminea or indoor fireplace. At www.growokc.com we also use instagram to show our pinion wood options at https://www.instagram.com/growokc_homestead/ and in the past we have mixed our pinion wood for sale with mesquite wood, mulberry wood, maple wood and persimmon wood. All these pinion wood blends and mixes make for a great evening by the fireplace.
I hear pinion wood is great for chimineas, outdoor fireplaces and indoor fireplaces. How does it repel mosquitoes in the summer time? do bugs hate the smell? I wish I could use it in cooking but it sounds like the sap ruin the meat. Is this true? Id like to order your pinion wood for sale and let me know. I'll email you, thanks
I was curious about the pinion wood for sale. I have heard it can repel mosquitoes in the summer time and also be a great smelling firepit wood or chiminea wood. Can I smoke meat with pinion wood or did native americans use it ? Thanks for offering pinyon wood or pinon wood or pinion wood
can pinion wood be used for furniture building other then using it for fire wood
Pinion wood is not a smoking wood for meat and other foods. I have never heard a good report of using it for cooking and smoking. But, the interesting part is that it is used in New Mexico for this because it is the one firewood for sale they have a plentiful supply of. Pinion wood is very sappy and it is a gymnosperm. Gymnosperms, pines, are not a good smoking wood for sale. One thing it is creates a lot of creosote which not only puts a thick film in the insides of your BBQ smoker but it coats your food. Since I have heard bad report after bad report, I have not tried it because I don't like wasting meat I just bought. But for chiminea wood and fireplace wood it is amazing. It is the only firewood for sale we have that is not used for smoking meat. Pinion wood for sale is amazing, just not for cooking and smoking meat. Thanks for your question, it was a great one Randy. Upchurch Cooking Firewood http://CookingFirewood.com
I've noticed that when I soak the pinion wood chunks in water that they are really able to smoke more. More smoke, more great smell. Thanks! Jacob, West Virginia
Can pinion wood be used for smoking meat? I have heard different things about pinion wood for sale and cooking and smoking. Since it is a pine and gymnosperm, I don't know. Thank you, Randy in Memphis
There is quite a bit of information on Pinion wood and why it is a favorite in the United States. Pinion wood, also spelled Pinon and Pinyon is a type of pine tree that grows in the Southwest parts of the United States. Pinion wood is a harder wood than Ponderosa Pine although may smell fairly similar the Pinion wood does smell better when it is analyzed. Pinion nuts are valuable in New Mexico and are sold similar to Pecan nuts are valuable in the Midwest. Pinion wood can be used in a chiminea, outdoor fireplace or outdoor fireplace. Upchurch Cooking Firewood sells pinion wood year round because it can be used 365 days a year. It is a well known mosquito and bug repellant in the summer time. We have been having some major insect problems and spraying deet and Off on your skin is very dangerous. Just simply light a pinion wood fire and the bugs will flee. Pinion wood for sale is also referred to as the "smell of Christmas" and is wonderful around the holidays. An important part of pinion wood is that it is not a cooking wood. No firewoods in the pine family are used in cooking. So buy your pinion wood for sale online today!
I love Pinion wood.
I love the Pinion wood for sale you have. I've used it before to repel bugs and mosquitoes. Being from Taos, NM I love the smell of pinion wood and it reminds me of home. Thanks for making it available and closr to me


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News & Press
Notice of Public Hearing 2017-2018 Budget
- Details
- Published: Friday, June 16, 2017
When: June 27, 2017 at 12:00 p.m.
Where: Board Room (Room #116) - 2100 J Street, Eureka
The Eureka City Schools Governing Board will hold a public hearing to receive public comment concerning the adoption of the 2017-2018 school year budget.
At the hearing, any resident in the District may appear and object to the proposed budget or any item in the budget. The hearing may be concluded on the proposed budget when there are no requests for further hearing on file.
Paul Ziegler
Assistant Superintendent Business Services
Eureka City Schools – Tel: 441-2412


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Central Arkansas vs Florida Atlantic (Mar 28, 2007)
Mar 28, 2007 at Boca Raton, FL
|Singles competition
|1. Claudia Kecht (FAU) def. Keilova, Petra (UCA) 6-2, 6-3
|2. Elodie Wendling (FAU) def. Colclough, Charissa (UCA) 6-1, 6-1
|3. Katherine Bartnik (FAU) def. Miller, Rebecca (UCA) 6-3, 6-1
|4. Natalia Totevska (FAU) def. Miller, Heidi (UCA) 6-0, 6-2
|5. Pia Terol (FAU) def. Paine, Jenny (UCA) 6-2, 6-4
|6. Danielle Simone (FAU) def. McCullough, Rebecca (UCA) 6-0, 6-0
|Doubles competition
|1. Claudia Kecht/Katherine Bartnik (FAU) def. Keilova, Petra/Miller, Heidi (UCA) 8-1
|2. Natalia Totevska/Pia Terol (FAU) def. Paine, Jenny/Colclough, Charissa (UCA) 8-3
|3. Elodie Wendling/Danielle Simone (FAU) def. Short, Jordan/Short, Lindsey (UCA) 8-3
|Match Notes
|Order of finish: Doubles (3,1,2); Singles (6,4,2,3,5,1)
Generated on 3/28/2007
Women's Tennis Season Ends in C-USA Tournament
Women's Tennis Opens C-USA Tournament Thursday
Bianca Biglione Named To Conference USA All-Aca...
Women's Tennis Wraps Up Regular Season Versus FIU
Women's Tennis Falls 5-2 Versus No. 45 Miami
Gutierrez, Owls Win Sixth Straight 6-1 Over Towson
FAU Player of the Week Honors go to Trio of...


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23 April 2017
This is always a favourite "last stop" when heading South out of Christchurch. The big sized bags especially the discount broken bags never fails to disappoint!
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08 January 2017
Disappointing compared with their Queenstown shop. No fresh cookies but a lot of packaged ones and souvenirs.
789 Main South Rd Templeton Christchurch


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In Project Diva 2 on PSP, Meiko get to have her own song and to be honest, it was the first time I see Meiko sing and dance. I never know how sexy she can be until I saw her doing "Change Me".
I like this number music arrangement together with choreography of the dance move. I never know Meiko can be so mature in her voice and look as the Meiko toy I have she look really cute.
More of my cute Meiko toy review.
For the game part, I manage to just clear the extreme stage of this song "Change me". It was not easy but still can manage to clear it with some practice. For those who want to know what "Change me" song is all about, here's one super MV with english lyrics.
So how much do you love Meiko now?
27 August 2010
Meiko Change me Project Diva 2
Done deal on Friday, August 27, 2010
Tag: Game , Project Diva , vocaloid
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text: University of Otago, Christchurch School of Medicine and Health Sciences http://hdl.handle.net/10523/224 Christchurch School of Medicine and Health Sciences 2017-06-24T01:42:30Z The key components of cancer nurse coordination: An integrative review http://hdl.handle.net/10523/7355 The key components of cancer nurse coordination: An integrative review 2016 Kerr, Christine With one in three New Zealanders experiencing a diagnosis of cancer during their lifetime, the New Zealand (NZ) national health care system plays a pivotal role in providing services to ensure optimal health outcomes for people diagnosed with this disease. In 2003 the NZ Cancer Control Strategy (NZCCS) set overall aims and objectives for improving care and reducing inequalities, and as one of many programmes driven by the strategy, the Cancer Nurse Coordinator Initiative (CNCI) was launched in 2013. The aim of this initiative is to practically support individuals and targeted populations who may otherwise experience barriers to accessing timely cancer care, and to provide this support the Cancer Nurse Coordinator (CNC) role was created. The CNC role is an advanced practice nursing specialty that is new to NZ, which resulted in a level of confusion and uncertainty regarding the concept and components of the role. The objectives of this dissertation were to identify common key components associated with care coordination services for cancer patients provided by nurses, and compare these with the NZ CNCI. An integrative review of international literature was performed to examine the topic. In order to best compare international practice to the NZ situation, inclusion and exclusion criteria were created that were in line with the current parameters of service for the CNCI; that is newly diagnosed adults with cancer, who were not receiving palliative care. Three synthesised findings were found, these focused on: the care given to the patient, interactions with health professionals and the system surrounding the patient, and the characteristics surrounding the role of the nurse. The findings from the integrative review were examined further and compared to the 2015 evaluation of the NZ CNCI programme. It was found that the key components of cancer care coordination as demonstrated by the CNC of NZ correlate with those articulated in the international literature for similar nursing roles. 2017-06-11T20:43:43Z Application of emerging sequencing and genomic technologies to diagnostic molecular genetics. http://hdl.handle.net/10523/7330 Application of emerging sequencing and genomic technologies to diagnostic molecular genetics. 2017 Kennedy, Hannah Louise The advent of massively parallel sequencing (MPS) has provided much broader opportunities in the field of molecular genomics. Previously, sequencing approaches were limited to a small number of single genes or exons. MPS has enabled assessment of hundreds or thousands of genes associated with a particular phenotype simultaneously, providing the clinical scientist with more information than ever before. This thesis examines the processes and challenges of introducing whole exome sequencing (WES) technologies into a clinical laboratory in three families, each with a distinct segregation pattern of an undiagnosed clinical condition. The challenges associated with the sequencing, analysis and interpretation of sequence variants, as well as elucidating mechanism(s) of pathogenicity of detected variants, were the focus of this thesis. One family with five male siblings affected with intellectual disability were initially investigated for a suspected X-linked disorder. Although candidate variants were identified, the results did not ultimately detect any clearly pathogenic variants or therefore a diagnosis. In a second family, a single affected daughter presented with an undefined ageing disorder. We identified a novel de novo X-chromosome variant in the gene BCL-6 co-repressor (BCOR), a G to A transition at c.3907G (p.Gly1303Ser). Although functional studies were not performed and definitive pathogenicity was not established during the course of this work, the BCOR variant was considered a strong candidate for this phenotype. Skewed X-chromosome inactivation was identified in this individual which is suggestive of an X-linked disorder, further supporting the role of BCOR dysfunction in her symptoms. The bulk of this thesis then focused on the analysis of a third pedigree in which four children have acute alcohol sensitivity and pronounced cardiac fibrosis, two of whom died suddenly. Exome sequencing revealed compounding mutations in the PPA2 gene, inherited recessively in all four children. PPA2 had not been previously associated with human disease, however, the enzyme encoded by PPA2 localises to the mitochondria, which implicated this enzyme in this family's disorder. In silico algorithms supported a damaging effect of both variants upon the protein, and early functional experiments in yeast and zebrafish were suggestive that PPA2 was important in cardiac function. This finding led to the identification of three additional families with PPA2 mutations in collaboration with laboratories in Germany and Austria. The phenotype of affected individuals in the European families was more severe resulting in infantile death, whereas the NZ family experienced death in the second decade of life following ethanol exposure. This work has established PPA2 as a new cardiac disease gene, and ended a diagnosis odyssey for a NZ family. It has also instigated an ongoing investigation into the mechanism of PPA2-associated disease. Exome sequencing in these three families has highlighted both the power of MPS to provide a diagnosis, and the challenges associated with analysing such complex data. In particular, the work has established a pipeline for the clinical laboratory which will need an associated laboratory for extensive follow-up functional analysis of candidate variants where a clinically significant impact has not previously been proved. 2017-05-21T22:02:59Z The role of hydrogen sulfide, substance P and Kupffer cells on inflammation and liver sinusoidal endothelial cells in sepsis http://hdl.handle.net/10523/7327 The role of hydrogen sulfide, substance P and Kupffer cells on inflammation and liver sinusoidal endothelial cells in sepsis 2017 Gaddam, Ravinder Reddy Sepsis is life-threatening organ dysfunction caused by a dysregulated host response to infection. The inflammatory response is an integral part of sepsis and leads to the systemic inflammatory response syndrome (SIRS) and multiple organ failure. The overall objective of this thesis was to investigate whether hydrogen sulfide (H2S), substance P (SP) and Kupffer cells modulate the inflammatory response, organ damage and liver sinusoidal endothelial cells (LSECs) fenestrations in sepsis. H2S is a key mediator of inflammation and recent studies have implicated H2S in the pathogenesis of sepsis. However, these studies have limitations due to the disadvantages of the H2S-synthesising enzyme inhibitor and H2S donors used to conduct the experiments. Gene deletion technology offers a definitive approach to investigate the role of H2S in sepsis. The aim of this thesis was to investigate the potential role of endogenous H2S synthesised through cystathionine-γ-lyase (CSE) using CSE knockout (CSE KO) mice in caecal-ligation and puncture (CLP)-induced sepsis. This thesis also aimed to examine the underlying mechanisms by which CSE-derived H2S regulates inflammation and to determine the interaction between H2S and SP in regulating the inflammatory response in sepsis. Kupffer cells are tissue-resident macrophages in the liver that play an important role in inflammation associated with infection. The studies described in this thesis investigated the potential roles of Kupffer cells on liver and lung injury, inflammation and the systemic inflammatory response in sepsis using gadolinium chloride (GdCl3) to inactivate these cells. LSECs are specialised fenestrated endothelial cells in the liver that undergo structural alteration during inflammation and infection. The structural alterations in LSEC fenestrae following CLP-induced sepsis were examined and the effect of GdCl3, CSE gene deletion and PPTA gene deletion (PPTA, a SP encoding gene) were determined. The final aim was to investigate the alteration of circulatory H2S and SP levels and their association with the inflammatory response in patients with sepsis compared to non-septic patients with similar disease severity and organ dysfunction admitted to the hospital Intensive Care Unit (ICU). Following CLP-induced sepsis in mice, increased expression of liver and lung CSE (liver: ~1.98 fold; lung: ~2.49 fold), increased liver H2S-synthesising activity (~1.27 fold) and plasma H2S levels (~1.45 fold) were observed. Mice deficient in the CSE gene showed significantly reduced sepsis-associated tissue (liver and lung) myeloperoxidase (MPO) activity, tissue (liver and lung) and circulatory levels of cytokines (TNF-α, IL-6 and IL-1β) and chemokines (MCP-1 and MIP-2α), and histological changes in the liver and lung. In addition, mechanistic studies revealed that the proinflammatory role of CSE-derived H2S was mediated by the activation of the ERK1/2-NF-B p65 signalling pathway. SP and NK-1R expression have been shown to play an essential role in sepsis-associated liver and lung injury. Mice with CSE gene deletion had significantly reduced tissue (liver and lung) and circulatory SP levels (liver: ~0.50 fold; lung: ~0.42 fold; plasma: ~0.61 fold) and tissue (liver and lung) NK-1R expression (liver: ~1.11 fold; lung: ~0.93 fold). This study showed that CSE-derived H2S in sepsis could upregulate SP and NK-1R expression, thereby contributing to liver and lung injury and inflammation. Examination of the effect of GdCl3 on the inflammatory response and organ injury following induction of sepsis showed there was protection against injury in the liver, as there was reduced MPO activity, cytokine (TNF-α, IL-6 and IL-1β) and chemokine (MCP-1 and MIP-2α) levels and histological changes in the liver. In contrast, administration of GdCl3 failed to reduce lung injury and inflammation (as there was no change in MPO activity, cytokine and chemokine levels and histological changes) and the systemic inflammatory response (as evidenced by no change in circulatory cytokines and chemokines) in sepsis. Study of LSEC fenestrae following induction of sepsis revealed that CLP-induced sepsis was associated with defenestration (decreased diameter, frequency and porosity) and gaps formation in LSEC fenestrae (~9 fold). Mice with CSE gene deletion, PPTA gene deletion and mice treated with GdCl3 showed less defenestration (increased diameter, frequency and porosity) and fewer gaps (~0.16 fold) in LSEC fenestrae following sepsis. Studies of septic patients admitted to the ICU showed higher circulatory levels of H2S and SP compared to non-septic patients, which correlated with the inflammatory response in septic patients. In conclusion, the results presented in this thesis have shown that the CSE-derived H2S, SP and Kupffer cells all play a key role in modulating inflammation, associated organ damage and LSEC fenestrae in experimental sepsis. This thesis has also shown that higher circulatory levels of H2S and SP are associated with inflammatory response in septic patients and are consistent with results from experimental sepsis, suggesting that CSE-derived H2S and SP play an important role in the inflammatory process of sepsis in both experimental and human sepsis. This study contributes to a better understanding of the pathogenesis of sepsis and highlights novel potential approaches to the treatment of sepsis. 2017-05-18T02:08:05Z Characterisation of the x-ray source and camera in the MARS spectral system http://hdl.handle.net/10523/7326 Characterisation of the x-ray source and camera in the MARS spectral system 2017 Shamshad, Muhammad This thesis reports on the characterisation of two modules of the MARS spectral CT system: the x-ray source and the x-ray camera. Understanding each of them directly improves material identification and quantification. A parameterised semi-analytical x-ray source model was developed. This work led to five published conference proceedings. Imaging performance of the CdTe-Medipix3RX detector was characterised. This research work gave rise to two provisional patents: an algorithm for unstable pixel identification; and a method for using unstable pixel clusters reliably; and in addition two published conference proceedings. As a part of the MARS development team, my research work has been and will continue to be used within the group for improvement in the MARS spectral capabilities. The primary feature sought from the parameterised semi-analytical x-ray source model is off-axis spectral variation. This aspect is overlooked in existing x-ray source models but is helpful in spectral CT. In addition, the models which do provide off-axis information do not match well with the specification of the x-ray tubes used in MARS spectral systems. This is an important aspect to consider in spectral CT since spectral detectors are sensitive to the polychromatic structure of the x-ray beams. Incorporating such variation in spectral image processing can improve the image quality. Our model provides off-axis information within ±17◦ along vertical direction (θ) and ±5◦ along horizontal direction (φ) of the central axis in the diagnostic imaging energy range (30-120 kVp). Comparisons of our model with existing models at central axis show good agreement (within 4%). In addition, the off-axis comparison of the model with experimental data collected with the MARS scanner was consistent within 3%. Temporal stability of the detector with different bias voltage settings was analysed by investigating variations in count with time. These investigations revealed that significant instability occurs within the first 5-10 minutes, after the application of the bias voltage. This showed that warm-up is required for a few minutes for stable operation of the detector. This instability was correlated with a rise in ASIC temperature. The effect of this instability decreases with increased bias voltage, which favors the use of higher bias voltages. The investigation of pixel behaviour facilitates the classification of pixels into malfunctioning, non-working and well-behaved pixels. Further investigations on the malfunctioning pixels revealed the slow drifting pixels which are hard to detect. To identify these malfunctioning pixels, a pixel masking technique is developed. A significant reduction in streaks and ring artefacts is observed with this technique. Further, it was identified that some clusters of malfunctioning pixels have correlated behaviour. This shows that when such clusters are treated collectively, they behave the same as a well-behaved pixel. This allows their use in image processing with minimal characterisation. In summary, an accurate beam modelling of an x-ray source and better understanding of the detector enable us to improve the spectral outcome of the MARS spectral system. 2017-05-17T04:42:55Z Genetic variation and mRNA splicing in familial breast cancer genes http://hdl.handle.net/10523/7319 Genetic variation and mRNA splicing in familial breast cancer genes 2017 Lattimore, Vanessa Germline variants in high-penetrance breast cancer susceptibility genes BRCA1 and BRCA2 are often identified through routine diagnostic gene screening, typically performed for individuals from high-risk breast-ovarian families. Many BRCA1 and BRCA2 variants are known to increase breast cancer risk by disrupting mRNA splicing and compromising the tumour suppressor function of these genes, which work to repair single and double stranded breaks in DNA. A significant number of BRCA1/2 sequence variants are located in or near splice sites and splicing regulatory regions and may disrupt mRNA splicing; however, the relative level to which mRNA splicing is modulated by these common or rare DNA sequence variants has not been ascertained. Splicing assays undertaken to assess the clinical relevance of rare sequence variants in BRCA1 and BRCA2 typically utilise a PCR-based approach and are able to detect the presence of aberrant isoforms and/or the absence of naturally occurring isoforms. The isoforms expressed are useful for determining the disruptive potential of each variant using the classification guidelines recommended by the ENIGMA (Evidence-based Network for the Interpretation of Germline Mutant Alleles) consortium. However, to date PCR-based assays used to evaluate potential BRCA1 and BRCA2 spliceogenic variants have typically only provided qualitative expression profiles. Thus, detection of quantitative and allele-specific expression changes, which may be associated with variants conferring disease risk, has been limited. Advances in sequencing platforms over the last decade have produced technologies that generate quantitative and high throughput expression information, simultaneously overcoming many of the limitations previously reported for PCR-based approaches in splicing assays. The work presented here exploits the capabilities of a targeted RNA-seq platform to generate the first comprehensive expression profile of normally expressed BRCA1/BRCA2 mRNA isoforms from lymphoblastoid cell lines (LCLs). Although a high degree of mRNA expression variability was identified across samples, the calculated expression levels made it possible to highlight changes present in rare variant samples outside the expected natural range. Additionally, results from this work identified instances where PCR-based assay primer design prevented isoform detection in variant samples. Targeted RNA-seq was coupled with allele-specific expression (ASE) analysis to further explore the potential spliceogenic impact of genetic variation in BRCA1 and BRCA2, highlighting ASE changes to natural mRNA isoforms for carriers of a rare variant. While the common variants included in this work were not found to have an obvious impact on splicing, observed allelic imbalances indicate that additional factors are likely to be influencing the mRNA expression variation seen. Exploration of this hypothesis found that common culturing practices, including liquid N2 storage and treatment with a nonsense mediated decay inhibitor, did not impact the mRNA isoforms expressed in a single LCL over time. However, the technology used for mRNA detection was found to play a significant role, with a direct relationship between the number of alternative events detected and the read depth in each sample. Further work into the extent to which cellular heterogeneity contributes to the observed mRNA variability was undertaken with a novel in situ hybridisation platform (RNAscope) to establish the level of variability in mRNA expression between individual cells. The results from this work highlighted how the inter-cell variation in BRCA1 and BRCA2 expression patterns is considerable, potentially explaining why variability is commonly observed when studying mRNA expression at a cell population level. Candidate gene analysis was completed for four patients who have a history of breast cancer but do not carry any disease-associated variants in BRCA1/2. This work did not identify any variants in other known susceptibility genes that are likely to have contributed towards their disease and further investigation into unexplored regions of the genome would be required to identify an underpinning genetic cause. Many women predicted to be high risk for breast cancer have yet to have their genetic basis successfully identified through genetic testing. The work undertaken here has established a technique to quantitatively assess BRCA1 and BRCA2 mRNA isoforms, while identifying technical and biological factors that influence the observed variability. This comprehensive analysis would benefit patient management as it provides a more informative base for variant classification from a better understanding of how disruptive any given genetic variant is likely to be. Clinicians and genetic counsellors will have the capacity to council patients more effectively as more variants of unknown clinical significance will be able to be given a classification that more informatively highlights their associated genetic risk. These more conclusive genetic test results will mean that patients are also less likely to be subjected to the stress and uncertainty that would otherwise be present with reported variants that remain unclassified. This work provides the basis for further studies to extend this work to other known breast cancer susceptibility genes, providing a more comprehensive assessment to identify variants that are likely to be influencing disease risk in high risk women. Such data will be critical for the future interpretation of splicing analyses in a diagnostic setting. 2017-05-14T20:57:00Z Neuropsychological Functioning and Ghrelin Secretion in Women with Binge Eating http://hdl.handle.net/10523/7273 Neuropsychological Functioning and Ghrelin Secretion in Women with Binge Eating 2017 Taylor, Kathryn Jan Aims: Binge eating disorders have a substantial impact on the lives of those affected, both psychologically and physically. The trend towards using a transdiagnostic model to understand binge eating disorders highlights the importance of understanding specific characteristics associated with binge eating rather than relying on diagnostic groupings to inform treatment. The aims of the current study were to examine neuropsychological functioning and ghrelin secretion patterns in women with binge eating to contribute to understanding factors that may be involved in the development and maintenance of binge eating. Method: Participants were 112 women with transdiagnostic binge eating using DSM-IV- criteria, who were recruited for the Binge Eating Psychotherapy Study (BEP), and 50 healthy control women. All participants completed the CANTABeclipse neuropsychological battery, the National Adult Reading Test-Revised and the Trail Making Test. A biological assessment of the neurohormone ghrelin, (total ghrelin and C-ghrelin), insulin and glucose after an overnight fast and then following an oral glucose challenge test was completed on 51 of the women with binge eating disorders and 46 of the heathy control women. Results: Key findings were: - No significant impairments were found in neuropsychological functioning in the domains of pre-morbid intelligence, attention, visuo-spatial perception and memory, and set-shifting in women with binge eating compared with women who do not binge eat. - Women with binge eating disorder performed more poorly on a test of verbal recall compared to women with bulimia nervosa and women who do not binge eat. -Neuropsychological functioning was not associated with higher rates of eating disorder severity, depression, anxiety or impulsivity in women with binge eating. - Total ghrelin secretion is blunted in women with binge eating compared with women who do not binge eat. - Some aspects of eating disorder pathology including frequency of binges, frequency of vomiting, extent of exercise, perfectionism and drive for thinness were associated with total ghrelin levels. - Ghrelin levels were not associated with neuropsychological functioning in women with binge eating. Conclusion: Results of the current study suggest that neuropsychological functioning is not significantly impaired in women with binge eating, and if relative impairments are present they are unlikely to have a major impact on overall functioning. However, it is possible that the specific neuropsychological tests used may have been of insufficient difficulty to demonstrate differences in this population. Significant differences in ghrelin secretion were found in women with binge eating suggesting that this may be a useful area to study further in order to understand binge eating. Further research in this area is warranted, with a particular focus on exploring factors which may contribute to the variation in ghrelin secretion among binge eating individuals. 2017-04-05T23:01:55Z Coping with the Impact of Multiple Sclerosis: A Grounded Theory Study http://hdl.handle.net/10523/7258 Coping with the Impact of Multiple Sclerosis: A Grounded Theory Study 2017 Keramat Kar, Maryam Introduction: Multiple sclerosis (MS) is an autoimmune disease that affects the central nervous system. MS generally progresses gradually, with alternating periods of remission, good health and disabling flare-ups. The impact of the disease results in people living with MS and their spouses having to confront a variety of changes and challenges in daily, family and social life. The aim of this study was to explore how people living with MS and their spouses cope with the impact of MS on their lives including daily activities, family and social functions. Methods: This qualitative study was conducted using a constructivist grounded theory approach. A purposive sample of 16 people with MS and 12 spouses were recruited in Qazvin in the north of Iran. Data were collected through semi-structured interviews with participants from October 2014 to January 2015. People with MS and their spouses were interviewed separately. Data collection continued until data saturation was reached, involving 37 interviews with people living with MS and their spouses. The interviews were digitally recorded and analysed using initial coding in the field of study. The recorded interviews were then transcribed and analysed through focused and theoretical coding. Throughout the analysis, codes and categories were constantly compared, and memos were written about them. Finally, codes, categories and memos were integrated through theoretical sorting and diagramming. A model of coping was developed with the core category and its connection with related categories demonstrated. Results: The analysis revealed the pathway, pattern and process of coping with the impact of MS. People with MS described a coping pattern with a certain direction and orientation. Direction of coping was related to the anticipated outcomes in relation to disease, self or others. Therefore, the sub-themes of anticipatory coping was categorised into self-directed, disease-directed or other-directed. Participants then focused on the orientations of coping drawing on certain strategies including actions, reactions, interactions and counteractions. The analysis also found that concurrent to the development of patterns and processes of coping, people living with MS managed their own or others' coping style through a concept named as "Meta-coping". Meta-coping was also the main coping pattern employed by spouses in order to deal with their partners' coping style. In meta-coping, participants changed their coping style through shifting between coping orientations mainly from reaction to interaction. They also worked through a process of meta-coping including considering, reflecting and responding. During the process of developing a coping pattern, participants moved between different pathways of coping which were identified as the "main", "transitional" and "maintenance" pathways. In the main pathway, participants coped directly with the situation through anticipatory coping and meta-coping. Participants sustained their main pattern of coping through the maintenance pathway or alternatively moved from the main pathway to the additional one in order to manage stress and promote their health. Participants also described coping in the context of commitment to coping, self-outlook, outlook to MS and life and support. Conclusion: This study has generated new insight into coping with MS through the perspectives of people living with MS and their spouses. The results suggest that coping starts with the anticipation of stressors, and coping is not limited to managing stressors; it can be used for dealing with coping for self and others through meta-coping. A model of coping has been developed contributing to theoretical development in the field and with clinical implications to enhance practice. 2017-04-04T21:10:36Z Exploring the anti-cancer and anti-inflammatory properties of isothiocyanates http://hdl.handle.net/10523/7254 Exploring the anti-cancer and anti-inflammatory properties of isothiocyanates 2017 Spencer, Emma Sue Isothiocyanates are a class of phytochemicals responsible for the characteristic tastes and odours of cruciferous vegetables. Epidemiological evidence indicates that increased consumption of isothiocyanates is associated with improved outcomes in a number of diseases, including inflammation and cancer. While many biological activities of isothiocyanates have been observed in vitro and in vivo, the detailed mechanisms that underlie isothiocyanate action are largely unknown. In this thesis, a library of structurally diverse isothiocyanates were examined for their ability to inhibit the pro- inflammatory cytokine macrophage migration inhibitory factor (MIF), and to trigger apoptosis. Isothiocyanates are known to covalently modify the N-terminal proline residue of MIF, inhibiting its tautomerase activity. The isothiocyanate library was tested for its ability to inhibit recombinant human MIF and also MIF activity in a human T-cell line. Structural differences in isothiocyanates were shown to influence their inhibitory capacity, with several compounds exhibiting low micromolar IC50 values in both systems. Inhibition of tautomerase activity was associated with a loss in the biological function of MIF in two physiological models. While MIF is known to have anti-apoptotic activity, there was no correlation between the ability of isothiocyanates to inhibit MIF tautomerase activity and their ability to trigger apoptosis. This suggests two independent pathways. It also indicates that isothiocyanates can be developed as MIF inhibitors that are not directly cytotoxic. Isothiocyanate-induced cytotoxicity was examined in more detail by investigating the role of the Bcl-2 family of pro- and anti-apoptotic proteins. Phenethyl isothiocyanate (PEITC) induced apoptosis via a classical apoptosis pathway involving Bax and Bak, and required the BH3-only proteins Bim and Bid. Intriguingly, however, the anti- apoptotic protein Bcl-2 could not protect the cells from phenethyl isothiocyanate (PEITC). Indeed, the Bcl-2 overexpressing cells were more sensitive to PEITC. The isothiocyanate has a greater effect on mitochondrial metabolic activity in the Bcl-2 overexpressing cells than wild-type cells. This suggests that isothiocyanates bypass the action of Bcl-2 by acting directly on mitochondria, and this information could be valuable for designing novel isothiocyanates that target Bcl-2 overexpressing cancer cells. 2017-04-04T02:25:52Z


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The abandoned border posts
The refugee crisis has reinstated the issue of the free movement of persons between the countries which signed the Schengen Agreement in 1997 on the agenda. This media helped the Polish photographer Josef Schulz to promote his series of images of the frontier military posts of the Old Continent, Ubergang, which explores the abandonment of these once austere infrastructures.
Schultz travels dozens of European sites in search of these stations in weather conditions that help integrate their present state into the landscape: fog, rain and poor visibility.
Today, Creative Boom explains, these posts do not belong to anyone, but simply remain without any kind of rehabilitation, manage their decay and merge past and present.
"Although the border police have long disappeared and the buildings themselves are defenseless, they still provoke a feeling of uncertainty, the result of the bad memories of a past that has divided Europe," the site continues. "The borders were lines drawn not only between territories, but also in our heads," concludes Josef Schulz.


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Had to do the same thing when I went to a Tigers game, and that was in DETROIT as well. Park close, stay together, carry some OC spray, and keep up your SA. You'll be just fine. Enjoy the game!
This is a discussion on Wish me luck within the Concealed Carry Issues & Discussions forums, part of the Defensive Carry Discussions category; I am getting ready to depart on a trip to PNC park in Pittsburgh to see the Phillies. I'm going with another father and his ...
I am getting ready to depart on a trip to PNC park in Pittsburgh to see the Phillies. I'm going with another father and his two sons and a daughter along with my son and daughter. I have to leave my gun at home for two reasons. One, I can't carry in the park and the hotel doesn't have a safe. Two, I'm reasonably sure that the other father who is driving wouldn't appreciate me carrying and leaving it in the car while we watch the game. I guess you call that living on the edge.
Had to do the same thing when I went to a Tigers game, and that was in DETROIT as well. Park close, stay together, carry some OC spray, and keep up your SA. You'll be just fine. Enjoy the game!
Better to die on your feet, than to live on your knees.
good luck!
God is love (1 John 4:8)
Good Luck!
"You can say 'stop' or 'alto' or use any other word you think will work but I've found that a large bore muzzle pointed at someone's head is pretty much the universal language."
NRA Member
Very safe area. Love PNC Park. Although I'm sure, like me, you feel like you're missing something anytime (and all the time) you aren't carrying, feel secure while you visit that area of the city. A lot of people and high police presence. Have a great time!!!!
"A strong body makes a mind strong. As to the exercises, I advise the gun. While this gives a moderate exercise to the Body, it gives boldness, enterprise, and independence to the mind . . . Let your gun therefore be the constant companion of your walks."
--Thomas Jefferson August 1785
Well I know you would rather be packin, but keep your SA and be safe.
Oh yea, enjoy the game!
I hate when I have to leave the gun at home. It's not a guarantee of safety but it sure feels better having it with than at home.
DEMOCRACY IS TWO WOLVES AND A LAMB VOTING ON WHAT TO HAVE FOR LUNCH. LIBERTY IS A WELL ARMED LAMB CONtestING THE VOTE.
Certified Instructor for Minnesota Carry Permit
NRA Pistol and Personal Protection Insrtuctor
Utah Permit Certified Instructor
Good Luck!
Does My Wallet Make Me Look Fat? It shouldn't because Obama is taking all my money.
I don't think they'll let you take OC into PNC park. On the other hand, if the security is like Heinz field, they don't check you very thoroughly and they don't have metal detectors. I'm not saying you should break the rules here.
When I had to go to Heinz Field a week or two ago, I ended up just leaving my gun in the car. My girlfriend did somehow sneak OC spray in. She handed it to me leaving the stadium. I don't even know...
PAFOA: Going to Heinz Field Tonight
"A well regulated militia being necessary to the security of a free State, the right of the People to keep and bear arms shall not be infringed."
You need more than luck to stay safe...stay alert.
Proverbs 27:12 says: The prudent see danger and take refuge, but the simple keep going and suffer for it.
Certified Glock Armorer
NRA Life Member
Luck to you, compadre.
And have fun.
I thought I read on another board about that park having storage lockers for people carrying to the game......
"The right of the whole people, old and young, men, women and boys, and not militia only, to keep and bear arms of every description, not such merely as are used by the militia, shall not be infringed, curtailed, or broken in upon, in the smallest degree..."
Nunn v. State GA 1848
ah, that uneasy feeling of traveling and attending a game without your
peace maker at your side. well good luck to ya.
stay safe and enjoy the game.
(SHERIFF BUFORD T. JUSTICE) "what the hell is
the world coming too"
good luck and have fun!
Glock 27,Hi-Point .380, S&W 3913, RIA 5" Tactical
NRA Member/Supporter
"Government is not the solution to our problems; government is the problem." - President Ronald Reagan


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103 Pins61 Volgers
DIY Tin Can Lanterns | Recycle tin cans into beautiful lanterns for just about any holiday or occasion!
Make mittens out of a shrunken sweater. | 27 Cheap And Easy Gifts To Make With Kiddos
idée pour placement de table pour fêtes de fin d'année :-)
make simple felt stars
upcycling tutorial.
Beautiful DIY Tea Candle Whisk Latern inspired by The Hundred-Foot Journey Movie Party – In Theaters August 8th
The little tutorial the teach you to do with broken cloth pattern T-shirt. Summer is coming, and your wardrobe to become more diverse
Concrete (sement) pine cones. Made with a mold. DIY on site (in danish)
DIY menu balloon ☆


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Friday, June 23, 2017
Warner Bros. Preps More Superhero Pics
With The Dark Knight breaking box-office records left and right, Warner Bros. is not surprisingly keen on bringing more Batman and other superheroes from the DC Comics universe to the ... Continue Reading →
Cage Will Kick-Ass
Mark Millar's bloody comic book Kick-Ass is headed to the big screen with actor Nicolas Cage attached to the cast, according to The Hollywood Reporter. The film is being directed ... Continue Reading →
Jackson Commits to Hobbit
Daily Variety reports that Lord of the Rings director Peter Jackson and screenwriting collaborators Fran Walsh and Philippa Boyens have officially announced their participation in New ... Continue Reading →
McAvoy, Blunt Mull Gnomeo Voice Work
Once in development by Walt Disney Feature Animation, the CG-animated feature film Gnomeo and Juliet is now in the works at Miramax and Elton John's Rocket Pictures, and may have ... Continue Reading →
Setback for Warner Bros. in Watchmen Suit
Warner Bros.' upcoming big-screen take on the Alan Moore graphic novel Watchmen could be one of next summer's biggest hits, or it could never be seen by audiences at all. ... Continue Reading →
Knight Vanquished by Thunder
After four weeks atop the North American box office chart, Warner Bros.' The Dark Knight has finally been knocked down a peg by the DreamWorks/Paramount comedy Tropic Thunder. ... Continue Reading →
Cryptozoo Discovered by Hollywood
Cryptozoo Crew from Jerry Carr and Allan Gross is the latest graphic novel series to get a big-screen deal. Daily Variety reports that Andrew Kosove and Broderick Johnson have acquired ... Continue Reading →
Relativity Eyes Voltron Movie
Ryan Kavanaugh's Relativity Media is in talks to pick up film rights to the giant robot anime series Voltron: Defender of the Universe, which was put into turnaround at 20th Century ... Continue Reading →
Animated Space Race in Theaters
Two animated movies set in outer space compete at the North American box office this weekend as Lucasfilm Animation's Star Wars: Clone Wars squares off against the stereoscopic ... Continue Reading →
New Release Dates for Bolt, Potter
Disney's upcoming CG-animated family flick, Bolt, will hit the screen sooner than anticipated, while Warner Bros. will leave Harry Potter fans waiting a bit longer for the next ... Continue Reading →


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Ginger Shrimp and Pea Pod Stir Fry
READY IN: 30mins
Recipe by PanNan
This is a very quick and delicious meal. It was inspired by another web site chef quite some time ago, and became a family favorite.
Ingredients Nutrition
- 1 lb jumbo shrimp, peeled and de-veined
- 2 green onions
- 1 cup chicken broth
- 1 tablespoon soy sauce
- 1 tablespoon sherry wine
- 1 tablespoon cornstarch
- 3 tablespoons water
- 2 cloves garlic
- 2 thin slices ginger
- sesame oil, for stir-frying
- 1 teaspoon sugar
- 1 1⁄2-2 cups pea pods
Directions See How It's Made
- Boil broth, soy sauce and sherry.
- Remove from heat and keep warm.
- Mix cornstarch with water and set aside.
- Stir fry garlic, ginger and green onion for 1 minute in oil.
- Add shrimp and stir fry for 2 minutes or until barely opaque.
- Remove from wok and set aside.
- Add more oil and stir fry pea pods.
- Add broth mix and boil.
- Add shrimp and heat through.
- Stir in cornstarch to thicken.
- Serve with rice right away.


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Resident Services & Special Events Facilitator
Cause Areas
WhenIt's flexible! We'll work with your schedule.
Where11201 Veterans Memorial Dr.Resource CenterHouston, TX 77067
Rainbow Housing Assistance at Champion Townhomes on the Green needs a volunteer to help out as a Facilitator for training classes, special events and general Resource Center Assistance. We only need about 5 hours per week. Regular set hours would be terrific, but we can be flexible.
Rainbow's Resource Centers provide assistive training, job services, agency referrals and youth programs to low-income housing residents in communities across the country. These are the people hardest hit by the economy, so your help is greatly needed, as well as appreciated!
- Mathematics
- Accounting
- Spanish
- Youth Services
- Environmental Science
- Customer Service
Good Match For
Kids Teens People 55+ Group
Requirements & Commitment
- Background Check
- Must be at least 18
- Orientation or Training
- Very Flexible schedule


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|Property type
|Minimum Stay
|2 nights
Silver Pines Estate is located in southeastern, Ohio in Coshocton County. It is 12 miles south of Sugarcreek, which is known as the Little Switzerland of Ohio. It is surrounded by beautiful pines and situated on a hill that gives you a spectacular view of the valley.
It is located among many Amish farms, and tucked away on a rural township road. It gives you the opportunity to rest and relax in the country, and leave your worries behind.
On the estate you will fall in love with the beauty and splendor of the countryside. The lodging consists of an A-frame built in 1982. It has four bedrooms, two full baths, kitchen, family room, living room, two wood burning fireplaces, walk out basement, and much more, all situated on twenty-six acres.
There are many walking trails on the property, as well as a small pond, that is stocked with fish.
The address for Silver Pines Estate
30281 Township Road 227 Fresno, Ohio 43824
Our names are Scott & Betsy Meyer. We have owned Silver Pines since 2002. We bought it for a place to get away, and wanted to offer it to other people to enjoy it as much as we do.
Scott Meyer purchased this cabin in 2002
We love the area. It is so peaceful, and the country side is breathtaking.
No major traffic congestion, just the occasional clip clop of an Amish buggy. All the amenities of home, but not the worries.
Always a great get away and so refreshing ! We love the quiet and the beautiful surrounding areas
Celebrated a friend's milestone birthday and it was so relaxing and quiet. Very clean and well stocked. Thank you Scott and Betsy.
Wonderful home in secluded wooded area with country views. Close to villages with many shopping options. Have made this a girls getaway destination once or twice a year for many years!
I would definitely recommend this house to anyone. The only problem is parking is a little tight if u have more than 2 vehicles.
From the moment we arrived I knew I wanted to come back. Beautiful property and the cabin is much more than a cabin, because it has so many amenities. It is very well maintained with a lovely view from every direction.
Even though you are out in the country, you are only 20 or 30 minutes from Amish country shopping and nice places to eat. The owner of the property makes everything easy for you. Looking forward to coming back. If you like to relax, this is the place.
John Tewell
The house and property are Great. We loved the layout of the house and it's location. The Grandkids enjoyed the loft to sleep and play in. Overall we enjoyed our stay, but it was to short. The directions to the property are accurate and the photo's we seen of the house where good. I would recommend this property to family and friends. Shop was close enough to enjoy. Our plan for the weekend was to relax and to enjoy the outdoors. We accomplished our plan and had a great time. This is the 5th time we have used homeaway.com for a family vacation and every location has been Great!
|Rate Period
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2 night minimum stay
|Notes: Rates are based on 4 guests; add $20 per night, per additional guest
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Rates are subject to change until reservation is confirmed.
100% refund if canceled at least 60 days before arrival date. After that date, a 90% refund will be issued.
Check in is at 3:00 pm and check out is at 12:00 pm


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Shakespeare's Globe has announced its exciting Summer of Love lineup which kicks off with Romeo and Juliet, then closes with Tristan Bernays' bold new ancient history play which tells the story of queen, warrior and rebel Boudica.
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Bankside is full of attractions that will make for an exciting trip, while not hurting your wallet.


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Stanley Wong (III)
Stanley Wong was born on June 8, 1987 in Louisiana, USA. He is an actor and editor, known for Now You See Me (2013), 21 Jump Street (2012) and 22 Jump Street (2014). See full bio »
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Welcome to Librarium Online!
Join our community of 80,000+ members and take part in the number one resource for Warhammer and Warhammer 40K discussion!
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hey all, first, i apologize if this thread is redundant. I played WHFB for several years, but quit right about the time the undead was split into TK and VC (5th ed? or was it 4th?) anywasy, at the time, i played a Nagash army, led by the same (still think he was the most broken special character ever) and when the split happened, i seem to recall them saying something about a 3 way split. 2 of the incarnations we have now, but the 3rd, which i assume was the armies of nagash, have never been brought back to life (yeah i know). so my question is, how do i go about making a nagash army? do i just use the VC list and not take any vampires? In the book it mentions in the index the bloodlines, as well as those commanded solely by necromancers, but then nothing more is said that i can find. i noticed there is a necro codex in the works in the forums, but i want something that i could take to a tourney if i so desire. again, please forgive me if this has been discussed before, but i couldnt find any answers to my satisfaction. i can;t even find out what the new story on nagash is, fluff-wise. any help would be greatly appreciated.
Armies: Dark Eldar
Space Wolves
(I don't like armies people actually play/write codexes for)
Remember Stigmar did kill Nagash. How great can he be =). You are right he was one of the most busted special characters.Originally Posted by Corporal Punishment
Vampire Counts recieved the short end of the staff from the Older Codex. Most of Nagash Items and Fluff went to Tomb Kings. I suggest you look to them first if you want to model after the old undead. We are almost complete different from the older army. We lack any of the old shooting elements. Mummies, Plague Carts, even Carriors were more tailoried to Tomb Kings. Vampire & Wights is the pretty much the only thing we carried over.
You can build necromancers list with out vampires, although without Vampire you will find you units lacking in brute power. You can always take Necrachs Blood Line, The Magic heavy blood line, and supply it with necromancers.
I think VC would be better because Nagash was a necromancer.. Since he was a fair good fighter as well you could use the rules for a Vampire Lord to represent him.
Also, there is still rumour of a Rise of Nagash campaign in the next year or two. GW said after SoC that he was 'too powerful' to have a model and rules again, maybe he'll get an army anyway...
The LO ANZAC Clan!
The Pirate's Haven BFG clan! Breathe life into this fantastic GW system.
One of the recent US WD's had a very undead"ish" army list in it. It described new units and stuff and brought back things such as mummies. This could be a precursor to the old Undead army and I actually am desperately hoping that something similar to the old Undead list will be released with the new army book.
You might want to take a look at that magazine if you are looking to play a Nagash type army. I'm not sure how well it will match up with your ideal, but hopefully it will come close.
are you referring to WD 308-310? with the heinrich keimler(sp?) army list? if so, your right, it is a lot closer to what i was looking for, though i would like something that can be used outside of friendly battles.
I like this rumor of a campaign, hopefully more info will become available on that.
Last edited by Corporal Punishment; March 14th, 2006 at 18:03.
Armies: Dark Eldar
Space Wolves
(I don't like armies people actually play/write codexes for)
Oh ok, good. You know about it already.
I didn't realize that this was for other than friendly games, so yeah, I guess you'll have to find a way to make a list within the current two "undead" armies.
I think your own suggestion was the best: Use the VC list and don't take any vampires... Or DO take a vampire and use the "counts as" rules and say that your vampire is actually something else while still using the rules for it. I only say this last part because a VC list without Vampires is really hard to do well. I've seen my friends try it and I typically crush them mercilessly with my Dwarves and Beastmen.
Hope that helps.
you know... if you really wanted nagash ... take a necrarch vamp lord... use a sweet looking semi nagash lookin model and call him nagash hes a strong catserjust liek nagash would be... I think itd be cool and well themed
What you are we once were. What we are you will become!!!
Too Powerful?!?! I can't believe that, yeah he would be a kick ass necromancer and okay in a scrap but look at other special character and you could say the same thing. Lord Kroak, almost 1300 point (I think) and Zach the Everling, rides a zombie dragon, (he's pushing 1200 points).Originally Posted by strewart
As for a proxy type character you could use in friendly games with friends permission... just use Zach the Everling on foot (point cost available in Vampire Counts Army Book). Seems like a good solution to the probelm until GW do decide if he should be allowed back onto the fields of war.
Ps I'd never let you use Zach he is way too powerful, mebbe play you once then when you finish the game with four time more models than you started with I would refuse to play you again.


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The Meadows of Rainbow City
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The Meadows of Rainbow City is good. The staff was very nice and caring. They have some activities, but I really wish they had a little more activities. The rooms were nice, clean, and spacious. Very reasonable in price plus it was two minutes away from where I live.
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Product / Service Categories
Project Name
Talk about this portfolio piece--who you did it for and why, plus what the results were (potential customers love to hear about real-world results). Discuss any unique facets of the project--was it accomplished under an impossible deadline?--and show how your business went above and beyond to make the impossible happen.
Product / Service Categories
Project Name
Talk about this portfolio piece--who you did it for and why, plus what the results were (potential customers love to hear about real-world results). Discuss any unique facets of the project--was it accomplished under an impossible deadline?--and show how your business went above and beyond to make the impossible happen.
Our First Project – Introduction to Project Management for Kids – Update Saturday, February, 11, 2017
Our group is a project management group and for our first project we taught teaching kids beginning Project Management and Coding/Programming skills in a 3 day class. Classes took place Saturdays, December 3 and 10, 2016 and January 7, 2017 at The MADE.org in Oakland , CA USA. Each day the first 2 hours of the 3.5 hr classes focus on project management and the last 1.5 hours focus on Scratch Video Game Coding/Programming. Scratch is a tool developed by MIT to teach kids 8-16 to code/program video games (https://scratch.mit.edu/about). We developed a project plan and roadmap to introduce the kids to project management tools, methods and concepts. The kids' projects were the actual 3 part class and a published video game on the Scratch site http://scratch.mit.edu. After completion of the class, each kid received a Certificate of Completion or Participation, a Scorecard and Superhero character (To use to represent their work and hide their real identity for safety reasons). Copies of each of our tools are at the bottom of this page.
Our Project – Create a Scratch Game: We partnered with The MADE (The Museum of Art and Digital Entertainment) in Oakland, CA, the Oakland Public School District and the Oakland Technology Exchange West to offer an introduction to Project Management and Video Game Programming class to students ages 9-15 years old. The Oakland Technology Exchange West is providing free recycled computers to our low income kids. Initially, we allowed a couple of 8 year olds to join the class with siblings. We also saved seats for kids who only signed up for Scratch Video Game Programming classes for that portion of the class. We invited a younger kid who was very good at programming and when we asked if he would help other kids he graciously said, "Yes". We didn't know until his mom returned the registration form and application that he was only 6 years old -wow (little genius).
We taught beginning project management classes from 8-10am and then our kids participated in The MADE Scratch Video Game Programming class. Our program consists of 3 mandatory classes to receive a Certificate of Completion in beginning project management and coding/programming of video games. Kids who participated but didn't complete the mandatory 3 classes received a Certificate of Participation. We offered a makeup class for kids who missed any of the first 2 sets of classes. We're working on making an online version of the class available for kids who miss 1 class.
The MADE has 15 laptops and workstations. For the first class (Saturday, December 3rd), 12 kids signed up and 8 kids attended the project management portion of the class. 9 more kids joined the Scratch portion of the class so we had 17 students and had to double up on a couple of laptops.
Since this is a pilot project, both PJMan & The StarGazers and The MADE were a little unprepared for the size of the group and the range of computer experience. All of the kids had experience playing video games but there were a few who had no or little computer experience. Because of this and all the excitement from the kids, the teachers didn't get to finish the game on the first day of class (Dec. 3, 2016). This was the biggest class ever for The MADE. There were times where they had to stop class to show a couple of kids how to right mouse click and copy and paste. As a result, for the next class (Saturday, December 10th) we took 30 mins. of the project management portion to teach beginning computing and an overview of Scratch.
Fortunately, during the second class on December 10th we were able to cover the project management material, the computing and Scratch overview information and complete the Scratch Video Game Programming class.
11 kids attended the project management section and 2 more kids joined us for the Scratch Video Game Production class. The kids created a maze game. It was amazing to see that each kids was able to follow the class and ensure that their game worked. Only problem was that they were spending so much time customizing their games that as the final new feature was added we ran out of time to do a final test. …and another feature of our project that I keep forgetting about is that when you take a class (always free) at The MADE you get to play the games in the museum – Old game like Atari and Nintendo (the old versions). So unfortunately, when the teach just announced we're out of time the kids took off for the games.
A makeup class was offered December 17th for any kids who missed any of the first 2 classes. 1 kids showed up for the project management portion and 6 kids joined the video game coding / programming portion of our class. The game taught was the Hippo Farm.
If you'd like to see our kids' work, go to http://scratch.mit.edu , use search to find our projects using pjmanthestargazers or click this link "pjmanthestargazers", Check in either the project or studio tab. Example_Maze_120316 and Example_HippoFarm_121016 are examples of how the games are supposed to work. Some games met their objectives while others didn't.
Since this is a beginning class, and unfair to the students we didn't get to complete the first game on December 3rd and we ended the class without fair warning December 10th when we met for our last class January 7th we will use this experience to further explain how real life IT projects work where you can have multiple iterations and testings (Betas, User, Alpha etc….). About 15 members of our project management group are in the process of testing the kids' game and offering feedback and encouragement.
As mentioned above, we are also partnering with the Oakland Technology Exchange. They provide free recycled to computers to low incomed families in the East Bay. Out of the 14 kids who are initially showed interest in our project, more than half of the families are low-incomed and working with Oakland Technology Exchange to receive free recycled computers.
Once all the kids have computers at home, we're going to give the kids (whose game don't have all of the features taught) the opportunity to remix their game so it has all of the features and works. You will be able to find the remixed games with our Scratch projects on the Scratch site.
Our final class was Saturday, January 7th. In spite of many challenges, 5 kids finished all classes with perfect attendance. 3 more need to makeup the last class. The last day of class I was getting over the flu and still suffering with laryngitis which I had for 3 weeks. One the first of a number of major storms in the Bay Area hit the morning of the last class.
Each kid received a Certificate of Completion or Participation, a Scorecard, feedback regarding their games, tools to management school projects and information regarding future classes and activities. We will also cover Lessons Learned for the kids projects and our programs: PJMan & The StarGazers / Project Management and The MADE.org / Video Game Coding-Programming.
Special thanks to the following:
The MADE.org (Museum of Art and Digital Entertainment) https://themade.org/
Thanks for teaching our kids beginning coding/programing in such a patient and fun way. It's nice to see teachers enjoying kids experience the joy of learning a new skill. We really commend this group for the work they are doing – all as volunteers.
Al Sweigart– Teacher: TypeRacer & The Maze, incoming Educational Director
Alex Handy– Program Director
Josephine Tsay– Educational Director (expecting momma)
Mark – Assistant teacher: Hippo Farm
Russell Spitzer – Teacher: Hippo Farm / Assistant Teacher: Type Racer & The Maze
Oakland Technology Exchange – http://www.techexchange.org/
Thanks for providing our low-income families with free recycled computers. In particular, Rayna and Domingo.
Lifelong Kindergarten Group at the MIT Media Lab
For developing Scratch to teach kids beginning coding / programming skills
Scratch is developed by the Lifelong Kindergarten Group at the MIT Media Lab. See http://scratch.mit.edu
Oakland Unified School District – Claire Shorall, Manager – Computer Science
Thanks for helping with recruiting efforts for the class.
My Elesson – Heman Johar
Thanks for use of Speedometer chart to use to explain stop light reporting (vs. rearview reporting) and for the kids scorecards. … and mostly for offering your assistance.
Construx Solution, Inc – Michael and Richard Pinks
Thanks for use of your free scheduling tool for our program and kids' project.
PJMan & The StarGazers Team Members and students:
Team members: Thanks for volunteering some of your extra time! Some of our team member volunteer hours and hours of time to bring this project to life. Others gave up about 30 minutes to an hour during the busiest time of the year (December 14, 2016 – January 3, 2017) to QA Test our kids' games. Most of our member's are from our LinkedIn group: PJMan & The StarGazers. Others were family and friends.
Sonja C. Stewart, PMP Founder / Project Manager/Curriculum Developer / QA Tester / Instructor
Donna Jacobs Quality Assurance Director / QA Tester
Brooke Dawson Quality Assurance Advisor/Project & QA Advisor / QA Tester
Elaine Jackson, PMP Holistic Project Management Consulting Creator of Student Application
Chantil Brown (Asia Stewart-Washington) – Bay Appeal Marketing Photographer / Videographer / QA Tester
Lynette Burris QA Tester
Hamed Fateminia QA Tester
Clara Jones (BingoBabe – Sonja's mom) QA Tester
Robert Rivas QA Tester
Kathy Soliz QA Tester
Kim Smith (SupeWoman) – Actress QA Tester
Sophia Stewart QA Tester
Howard Ware – The Financial Quest QA Tester
Students and future Coders/Programmers & Parents:
Thanks for waking up early to arrive at class for 8am on your Saturdays. Click on superhero name to see game,
Basketballman 10 years old BasketballMan's 2nd Game 01/07/17
Batman 8 years old
CatGirl 13 years old CatGirl's 2nd Game 01/07/17
CatWoman 10 years old
CP Dash 9 years old CP Dash's 2nd Game 01/07/17
Gizmo 13 years old
Jarock 11 years old
OOO 9 years old
Pandaman 11 years old PandaMan's 2nd Game 01/07/17
Redhood 13 years old
Raxxessroar 6 years old
SpiritDragon 9 years old
TQ 10 years old
Oh, yes. We do code. Teachers games:
Brooke Dawson, PMP aka ChimChim-Cheree
Donna Jacobs aka PrimaDee
Sonja C. Stewart, PMP aka PJMan This is the game that started this project. I created this game by building from scratch. I took a class on Coursera then created this game. I then tried another game and ran into a problem. I found out about The MADE . They were teaching free Scratch classes for kids. I was going to crash the class but I found out the class was for kids first, then their parents then adults.
PJMan's 3rd Game during Global Game Jam @ The MADE 012117
Project Management Tools:
Project Plan (Coming soon!)
For more information, contact Sonja @ (510) 269-4814 or firstname.lastname@example.com.


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I only stayed one evening but the stay was nice or the rate. staff was VERY nice and professional. The exterior looks a little dated so I was worried about the rooms. They were nice and clean my only complaint was the pillows and quality...More
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Getting you more information on this room
"If you have to stay here, I would suggest you preview the room BEFORE YOU PAY."


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In this most recent body of work, Bec Juniper relates to the remote Western Australian landscape as distinctively feminine, despite many of the area's activities, such as mining and fishing, being traditionally associated with a masculine gender. Drawn to the desert and open spaces in a meditative way, Juniper uses intuition, employing different techniques with a buffet of natural materials from oxides and ochres. In the midst of nature and surrounded by the vastness of space, she feels the landscape's overwhelming depth of colour and sensation more than she could ever imagine. This quality of interaction is inspiration for her new body of work: More Than I Can Imagine.
Bec Juniper Talks About Her New Series


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my 2001 toyota MR2 won't start,won't even make a sound,just the click of the key and only starts when ever
won't even make a sound,just the click of the key and only starts when ever,some times
i'll drive it for days with out any problems but then i'll go to the market and just won't
start,some times i have to leve the car seat for hours or even days so that it will start
again..do you know the answer??
3 Answers
It may be a bad ground, grounding issue, or a loose starter cable nut
I did when I turn the key I can hear the fuel pump but the car don't do anything
check the kickstarter
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DB Peru's core mission is to provide medical treatment and care to the people in the villages along the lower Napo River. This international volunteer effort includes doctors, nurses, nurse midwives and technicians working along side local healthcare professionals in the jungle. Temporary clinics are most often set up in the village schoolhouses. Medicines and supplies are either donated by private persons or businesses, or purchased from the Minister of Health in Peru.
All patients are registered and most of the healthcare needs are addressed in the villages. Those with chronic conditions, more serious illnesses or injuries receive follow up visits. However, when patients are in urgent need of more advanced care and treatment, they are transported to local clinics and/or hospitals.