text:
We love celebrating bad writing. There's the
for the worst first sentence; the
, which seeks out the weirdest book title; and the
Literary Review
's Bad Sex in Literature Prize, for which the finalists were
Nominees range from James Frey and Stephen King to Sebastian Barry and Haruki Murakami. The
posted snippets from the worst offenders on their
On Canaan's Side
, by Sebastian Barry: "We got rid of our damned clothes, and clung, and he was in me then."
Ed King
, by David Guterson: "…at the moment of their mutual climax, Ed made sure Diane was on top."
Dead Europe
, by Christos Tsiolkas: "My tongue furiously worked the craters."
The Final Testament of The Holy Bible
, by James Frey: "Every part of my body sang some song I had never heard."
Here's the complete list of nominees:
The Great Night
by Chris Adrian
The Land of Painted Caves
by Jean M Auel
On Canaan's Side
by Sebastian Barry
The Affair
by Lee Child
The Final Testament of the Holy Bible
by James Frey
Ed King
by David Guterson
by Stephen King
by Haruki Murakami
Parallel Stories
by Péter Nádas
Outside the Ordinary World
by Dori Ostermiller
Dead Europe
by Christos Tsiolkas
Everything Beautiful Began After
by Simon Van Booy


text:
Related Publications
- Related by Author
- Related by Topic
Related Links
Participation and Leadership of Senior Citizens; Implications for Programming
By Felice Perlmutter, CherylAnne Lieberman
Jewish Communal Service Association of North America (JCSA), National Conference of Jewish Communal Service, Fall 1971
Topic: Jewish Community Centers (JCCs), Survey, Jewish Organizations, Affiliation, Aging, Elderly, Community Centers
Name of Publication: Journal of Jewish Communal Service
Editor: Sherman, Sanford N.
Volume/Issue: Vol. 48/No. 1
Page Number(s): 85-90
Genre: Article
Coverage: Philadelphia, Pennsylvania
Language: English
Copyright Holder: Publisher
Copyright Information: Download for personal use, freely distribute link
Bibliographic Information:
Perlmutter, Felice. Lieberman, CherylAnne. Participation and Leadership of Senior Citizens; Implications for Programming. Journal of Jewish Communal Service. Jewish Communal Service Association of North America (JCSA),National Conference of Jewish Communal Service. Fall 1971: 85-90. http://www.bjpa.org/Publications/details.cfm?PublicationID=4479
» View Publication
(PDF, 421 Kb)

subset: commoncrawl


text:
Lorde finally met Royals great George Brett
In case you didn't know, Lorde said that her inspiration for her #1 song 'Royals' was a photo she saw of Kansas City Royals great, George Brett in an old National Geographic magazine
Scheduling conflicts have prevented Brett from meeting Lorde in person on her tour, so he sent her a signed jersey that said "Lorde, you are Royal to me".
BUT, before her show in Vegas, Brett and Lorde finally met up...and thus concludes of Lorde/Royals story....
And now you're Royal. @lordemusic meets @Royals icon George Brett. pic.twitter.com/7BPRW6VYJD
— MLB (@MLB) April 16, 2014
Listen to 'Lorde Radio' on iHeart Radio


text:
Ask E. Jean: The Give and Take Behind Closed Doors
I give and give and give but my boyfriend doesn't return the favor
Dear E. Jean: I give, but I don't receive. My boyfriend of eight months and I have an amazing sex life. He's adventurous, spontaneous, and caring (not to mention good-looking!). There's only one problem—he dislikes performing oral sex on me. He's done it before and I've enjoyed myself a lot, but now he's admitting that it doesn't turn him on and that it mildly disgusts him. To me, giving and receiving oral sex is an important part of a healthy sexual relationship. Is there anything I can do to change his mind? —Giving, Not Receiving
Giving, my girl: What we have here is a simple case of Male Lockjaw—the scourge of modern women—but, huzzuh! We can fix him. Netflix The English Patient. Cue up the scene where Kristin Scott Thomas strolls into Ralph Fiennes' Cairo apartment wearing the white cotton dress. Watch closely as Mr. Fiennes drops to his knees and buries his face between Miss Scott Thomas' legs. Are you watching? Okay. Run it again. But now study Miss KST's reaction.
Stunning! She's beating Mr. Fiennes about the head and shoulders! She's forbidding him the treat! It's the oldest trick in the book: If you beg a man for a treat, he'll recoil; if you refuse him a treat, he'll burn to have it. "Hunger is intensified by fasting," as Guy de Maupassant says about sex.
Move forward a scene...stop! Where are Mr. Fiennes and Miss Oscar Nominee now? That's correct. In the bathtub. I suspect your boyfriend has suffered a "cleanliness" thing since childhood and is put off by the exotic perfumes of sex. Make the tub and shower your training ground, and, with a little deft maneuvering, voilà!
E-mail your questions to firstname.lastname@example.com


text:
IPO Education Foundation Rewards Innovation and Creativity at Awards Dinner on Monday, December 10
05 Dec, 2012, 11:32 ET from Intellectual Property Owners Education Foundation
WASHINGTON, Dec. 5, 2012 /PRNewswire-USNewswire/ -- On Monday, December 10, 2012, Intellectual Property Owners Education Foundation will honor 39th Annual National Inventor of the Year Alex Kipman, 2012 Distinguished IP Professional Judge James Holderman, and the six winners of the Second Annual IP Video Contest, in a ceremony at the Smithsonian American Art Museum and National Portrait Gallery. Members of the media can RSVP to attend by contacting Colleen Wellington-Caban at 202/507-4502 or email@example.com.
The National Inventor of the Year Award fosters the spirit of American innovation. This year the Foundation will present its award to Alex Kipman from Microsoft for his role on the team that invented Kinect, the motion sensing input device developed for the Xbox 360 video game system and Windows PCs. According to an article in New York Times Magazine on May 31, 2012, Kinect set "a Guinness World Record for the fastest-selling consumer device ever," selling 8 million units in the first 60 days after its release. Kinect revolutionized personal entertainment with its ability to fully recognize and adapt a human's form and gestures into video game and other entertainment experiences. Among other honors, Kipman was named one of TIME Magazine's 2011 100 People of the Year.
The Distinguished IP Professional award recognizes an individual who has demonstrated extraordinary leadership in the intellectual property community and a lifetime commitment to invention and innovation. This year the Foundation recognizes the Honorable James F. Holderman, Chief Judge, U.S. District Court, Northern District of Illinois. During his more than twenty-five years on the bench, Chief Judge Holderman has presided over numerous cases in all areas of federal jurisdiction. Currently the Northern District of Illinois is one of fourteen United States district courts participating in a ten-year program designed to evaluate the adjudication of patent cases. Chief Judge Holderman teaches IP courses at John Marshall Law School and at the University of Illinois College of Law. He has been honored numerous times for his contributions to the intellectual property community.
The Foundation created its IP Video Contest in 2011 to educate teens and the public about the importance of the patent system. Young adults in three age categories are asked to illustrate in an original video why they think the patent system is important. Winners receive scholarships and cash prizes. The 2012 winners are Alexis Salcedo of Bethesda, MD and Sam Marlott of Elmhurst, IL in the 13-15 category, Lewie Kloster of Minneapolis, MN and Jason Girouard of Brimfield, MA in the 16-18 category, and Reggie Schickel of Urbana, IL and Matthew Kim of Temecula, CA in the 19 and over category. Their outstanding videos are posted on the contest website at www.ipvideocontest.com.
SOURCE Intellectual Property Owners Education Foundation


text:
Registration takes less than 1 minute.
A group of 32 chief executive officers wrote a letter to the White House, saying they are willing to work with the administration to "modernize" the deal rather than on an overhaul that starts from scratch, the Wall Street Journal reported.
Heavy rains and flooding throughout the Great Lakes and St. Lawrence River region have authorities considering shutting down the seaway for shipping until water levels recede.
The Canadian government will provide C$867 million (U.S. $643.1 million) in federal loans and loan guarantees to the country's forestry industry as it battles U.S. countervailing duty measures against softwood lumber shipments bound for the United States.


text:
The role of angular momentum in collision-induced vibration–rotation relaxation in polyatomics
McCaffery, Anthony J., Osborne, Mark A., Marsh, Richard J., Lawrance, Warren D., & Waclawik, Eric R. (2004) The role of angular momentum in collision-induced vibration–rotation relaxation in polyatomics. Journal of Chemical Physics, 121(1), pp. 169-180.
|PDF (191kB)
Impact and interest:
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Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.
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|Journal Article
|Past > QUT Faculties & Divisions > Faculty of Science and Technology
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|Copyright 2004 American Institute of Physics
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text:
With the advent of gaming becoming so popular, sooner or later it will affect specific industries and target new customers including adults. One such industry is the legal industry where there is a game using data from statutes, cases and other state-specific rules. Even though this game targets those who are interested in being a trial lawyer, other attorneys could find benefit as well whether or not they have any previous courtroom experience.
There are several other industries where games are starting to make impact such as:
- military
- music
- business
- urban planning
- fitness
- medicine
- education
- dentistry
- engineering
- relationships
- construction
What do you think? Which industry-focused games do you enjoy and think actually benefit the end user with realism and enhancing skills?


text:
Payday Loan Kitchener
Financial hardship is a very difficult thing to endure, so if you're facing these circumstances, you may want fast cash. For some consumers, a cash payday loan can be the approach to take. Keep reading for many helpful insights into Payday Loan Kitchener, exactly what you need look out for and the ways to make the best choice.
Hidden fees are very prevalent when dealing with Payday Loan Kitchener. You have no method of knowing what you're charged if you do not ask. Make sure the questions you have are clear and direct. Some people find out that they owe a lot more than they originally thought after getting a loan. Steer clear of this pitfall by making sure to read all the documents and asking all critical questions.
Never be dishonest on a loan application! You may be tempted for one reason or another, but it's illegal and can get you into trouble.
Consider simply how much you honestly require money that you will be considering borrowing. If it is something could hold off until you have the money to purchase, put it off. You will likely realize that Payday Loan Kitchener are not an affordable option to buy a big TV for the football game. Limit your borrowing through these lenders to emergency situations.
Check with the BBB to make certain the payday lender you are looking for has a good rating. Check their BBB ratings for virtually any complaints prior to signing for a pay day loan with any organization. If you discover any complaints, you then should probably hunt for another company. If you find none, then its probably safe to use them.
Are you having difficulty paying your bills? Do you need to get hold of some money without delay, and never have to jump via a lot of hoops? If so, you might want to think about obtaining a payday loan. Before the process though, look at tips in the following paragraphs.
There is an abundance of payday loan companies that are desperate to loan you cash. If this type of loan should be used, be sure to review the lender's history before proceeding. Find out if others also have good experiences with them. A quick online search can present you customer reviews and complaints.
You must have an ongoing work history one which just qualify to secure a payday loan. Many lenders should see proof a minimum of 90 days worth of employment before granting that loan. The lender in most cases require you to submit pay stubs to them as evidence of your valid work history.
Be aware with the deceiving rates you're presented. It may seem to become affordable and acceptable to be charged $ 15 for each one-hundred you borrow, nevertheless it will quickly add up. The rates will translate to be about 390 percent of the amount borrowed. Know exactly simply how much you will be necessary to pay in fees and interest beforehand.
Do not think the process is nearly over once you have received a cash payday loan. Put your paperwork in a safe place, and write down the payoff date for the loan for the calendar. Not making payments find yourself being too costly and those costs and consequences quickly add up.


text:
Kid Hygiene: Brush Your Teeth Printable
I was talking to my sister-in-law about my kids' cavities this morning. She mentioned her kids had a few cavities the last time they went to the dentist so she had to really start getting on them about flossing.
Flossing? Man, I struggle to remind them to brush!
I needed a better way to get my kids' more concerned about their dental hygiene. We all know by now my consistency level is pretty low, so even when I try to "remember," it's spotty at best.
{I barely remember where my cell phone is less than a minute after it leaves my hand.}
I wanted to come up with a painless way to reward them for brushing their teeth. I love sticker charts (grab my potty training chart here, or my morning routine chart here), so I figured, why not a brushing and flossing chart? I like to use sticker charts just long enough to start a habit. After that, the novelty has worn off, and it goes back to me trying to remember to remind them to use it.
Which defeats the purpose.
So I whipped up a quick little flossing chart. It's bright and colorful and your kid gets a reward when the chart is full!
For all my kids struggle with brushing their teeth, they love new toothbrushes. What better reward for a full brushing and flossing chart than a brand spanking new toothbrush?? However, if your kid is resisting brushing their teeth at all, I would start by letting them pick out a new toothbrush (Spiderman or Cinderella toothbrushes, anyone?), some new kid-friendly toothpaste, and maybe some bubble gum scented floss!
Let them pick a different reward entirely, or perhaps something else teeth-related. Did you know they have pre-brushing mouthwash for kids that turns their teeth blue? When the blue is all gone, they can stop brushing!
Are you ready for your freebie? Click below to get a free printable Brush and Floss chart!
Do your kids struggle with brushing their teeth? Do you struggle to remind them?
2 Responses to Kid Hygiene: Brush Your Teeth Printable
[…] And finally, my 9-almost-10-year-old gives her review: "It's AWESOME!" For further motivation and inspiration for toothbrush battles, check out my free "Brush Your Teeth" printable! […]
Skylanders Giants CynderFollowing on the heals of a angking outfitters
woodstock hours successful campaign in the first place.
They are the ancient ones and the earliest gatekeepers of
the Skylands.


text:
News By Tag
Industry News
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Industry News
Sports Litigation Alert Reports on Chicago Bears Case
Illinois District Court upheld the decision in a Chicago Bears Case
The United States District Court for the Northern District of Illinois has upheld the decision of an arbitrator that members of the Chicago Bears could not pursue workers' compensation claims in California and must do so in Illinois. The Court held that the players were unable to establish any basis for concluding that the negotiated agreements between the parties must conform to California public policy.
In 2009 and 2010, three Chicago Bears football players, Michael Haynes, Joe Odom, and Cameron Worrell, filed claims for workers' compensation benefits with the California Workers' Compensation Appeals Board. The Bears filed grievances with the players, arguing that they violated their contracts by pursuing their claims in California rather than Illinois.
Other case summaries include:
Coach Fails to Establish Retaliation Claim
Minnesota State Appeals Court Upholds Award to Assistant Coach
Famous Athletes Lash Out at Those Who Use their Name, Likeness or Other Personal Attributes Without Permission
Harassment by Athletes Fails to Meet Threshold
Articles Include:
New Laws Help Student-Athletes Ask the Right Questions During the Recruiting Process
Officials Share Insights as to Why Emerging Sports Leagues Have Been Successful
NBA Season at the Crossroads
Colangelo Begins Work on a New Project -- the Jerry Colangelo School of Sports Business
When Lightening is Imminent Stadium Evacuation Procedures Take Center Stage
Pace Joins Arent Fox as Partner in New York Office
Read more in the latest edition of Sports Litigation Alert.
Coming out 24 times a year, the Alert features a searchable archive of more than 1000 case summaries and articles pertinent to the sports law field.
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text:
Proof of Tea Party Racism? Mooooo....
Posted in the Grand Rapids Forum
1 - 20 of 160 Comments Last updated Apr 26, 2014
#1 Mar 14, 2014
[When asked by a Fox news reporter for examples of Tea Party racism liberal protesters get uneasy. According to one woman, "they're racist against Blacks, Hispanics...I think their racist against...women."]
The video is both sad and laughable. It's no wonder they voted for a community organizer, with virtually no economic, leadership, business or foreign relation experience, based entirely on his skin color and a bunch of untenable giveaway promises.
#2 Mar 14, 2014
Low information voters come from Progressive "useful idiots"..... Lenin would be proud........
#3 Mar 14, 2014
Hey Stupid ..... I already addressed this B.S. about three weeks ago. Here's the truth on this Faux ambush and trick video.
The faux 'correspondent' asking the questions was David Webb a paid Faux contributor and Breibart columnist.
The video shows Webb asking marchers to give examples of racism by the Tea Party. This is the sort of AMBUSH TACTIC that serves no purpose other than to create a negative impression of the respondents. First of all, Webbs video showed him interviewing ONLY four people out of the more than 80,000 who attended the march. Without the UNCUT VIDEO we have no idea if there were forty others who supplied Webb with bona fide examples of Tea Party racism that he left on the cutting room floor. Its easy to splice together just the remarks that make his point and discard the rest.
Furthermore, the respondents were NOT official spokespeople for the protest and they did not come prepared to have answers for Webbs LOADED questions. Its unreasonable to expect that random citizens participating in a march to protest specific policies of North Carolinas ultra-right Republican administration will be carrying documentation of Tea Party racism to an event that isnt related to that subject. Yet that is precisely what was expected of the four victims of Webbs inquisition. Fox Nation even placed a story about this at the top of their website with a sensationalized headline that implied that liberals as a group were unable to cite examples of bigotry in the Tea Party.
So you fail again Stupid. How does it feel to be slapped around again today Tutu?
#4 Mar 14, 2014
Did aliens rape you or something......... What is wrong with getting paid at a job....... You should be required to wear a helmet.........
#5 Mar 14, 2014
Its not about Webb getting paid Dumbo -- its about Faux Ambush Tactics. This is another faux nose video that they use to make people like you even more stupid than you are, if that's even possible.
And You're really that stupid aren't you Hot sauce boy?
#6 Mar 14, 2014
Old Soviet tactic being used by the left. Accuse and separate.
#7 Mar 14, 2014
Your late for work poledancer!
#8 Mar 14, 2014
Sorry for the mis spelling. I no it irritates u.
Ur late for work poledancer!
#9 Mar 15, 2014
Ambush? Those people interviewed claim they were activist so they should know political landscapes. They are the low information voter like you...... When was your last grey visitor in for the probe.
#10 Mar 15, 2014
I don't know, when, if ever, I ever get slapped around I'll tell you. Thus far you've only managed to slap yourself silly with your own ignorance.
This response, like the last time you posted it - and undoubtedly the next dozen times you regurgitate it ad nauseam - does virtually nothing but offer a lame excuse of why there remains NO proof of racism in the Tea Party.
These poor saps were wasting their time protesting the "ultra-right", and still couldn't provide a single incident of racism. Not ONE!
I'm not even protesting and I can provide countless incidents of racism coming from Obama-supporting radicals, from King Shahalababa-shithead screaming about "killing all dem cracka babies and dey cracka mommas..." to Louis Farrakhan, to the Rev Wright, to your very own moronic vice president Blowhole referring to President Mom Jeans as,I mean, you got the first mainstream African-American who is articulate and bright and clean and a nice-looking guy, he said.I mean, thats a storybook, man.
From your little radical figure head Nancy Pelosi taunting Tea Party members by traipsing arrogantly and unnecessarily through their ranks with a gigantic gavel in her hand, to the the black caucus members and Emmanuel Cleaver FALSELY claiming a Tea Party member spit on him and hurled racial epithets ...
... you radicals have been trying and failing to prove racism in the Tea Party ever since the movement began - and you've FAILED every single time. So, FOX calling you low info retards on your false narrative is absolutely fair game.
#11 Mar 15, 2014
Who needs to ask a liberal marcher to provide the proof when you can get the news straight from the GOP. The following is just part of the sad story of a Tea Party Darling.....
"GOP congressional candidate Drew Turiano has been branded a racist by the Yellowstone County Republican Party and turned away from the groups key political event.
We asked Mr. Turiano not to attend our event because we have no intention of allowing him a platform to spread hate and intolerance, said Jennifer Owen, Yellowstone County Republican chairwoman.There is simply no place for racism in this party.
#12 Mar 15, 2014
Turiano who?
A completely insignificant candidate who, if this story is even true, was rightly dismissed immediately.
If this story is even true it only proves how quickly racists are dismissed by the right when they crop up.
When are you libtards going to address Biden's bigoted gaffe about how clean a black guy Barry is?
Oh that's right, racism is allowed on the left - in fact, it's elected!
#13 Mar 15, 2014
Yup, as soon as you provide a credible story of a racist member of the tea party, Dingbat reverts to his own version of childish insults and refuse to either admit the facts or find evidence to refute it....... Who's surprised about that one?
"Russian ties?"
Since: Mar 09
#14 Mar 15, 2014
We asked Mr. Turiano not to attend our event because we have no intention of allowing him a platform to spread hate and intolerance, said Jennifer Owen, Yellowstone County Republican chairwoman.There is simply no place for racism in this party.
Thanks for the proof that the Tea Party is NOT racist.
Too bad we cant say the same thing about Obama's own minister Reverend Wright.
I think it's sad that those on the left have to keep using the race card because they have no other excuse.
#15 Mar 15, 2014
I get that you found some story about a nutball racist who claimed to be a Tea Party "member", but that's hardly damning proof. Everything I read about this guy (and there wasn't much) who no one had even heard of, seems to point to the fact he was summarily and publicly rejected by republicans for his racist views that do not reflect the party's philosophy.
Using that logic, I guess if the OWSer movement were still around I could claim to be one, run around like a black teen knocking out innocent, unsuspecting white people, and then call that proof of the OWS's violent, racist behavior??
#16 Mar 15, 2014
I see more racism from progressives policy to close charter schools and eliminate school choice......... How about the bigotry from SEIU when Conservatives give $100 million to a hospital to help pay for care..... Where are the libs to donate to charities....... Top libs in the country give very little.... Hey, make sure you split extra wood for your heat tonight....... And stop bugging the women at Pappy's bar..........
#17 Mar 15, 2014
Don't forget crapping over everything like libs do........
#18 Mar 16, 2014
Like the other village idiots in that movement, comprehension skills are NOT required.
If you had read the entire article, you would note that Mr. Turiano claims to represent the Tea Party. It was the mainstream republicans, also known as RINO's that decided that they didn't want to listen to his racist rants.
Radical Conservatism is the real mental disorder......
#19 Mar 16, 2014
Of course it isn't damning proof to you. He wasn't known to you, but he was known to the republican RINO's in that state, and they didn't want to listen to his racist bagger crap.... That's the proof!
Time to change the subject now that proof has smacked you upside your melon once again.
How's that BENGHAZI investigation going?
Any more Obamacare horror hoaxes?
#20 Mar 16, 2014
Pssst, Bobbie, you're Projecting again..........
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text: What lovely pictures the Sun carried last week of Prince William and his crew during Royal Navy manoeuvres in the azure seas off Montserrat. Shame, then, that blog Photoshop Disasters should spoil the fun by pointing out that the pictures on the website and the pictures that appeared in the printed edition didn't seem to quite match up. A charming piece of ethnic cleansing, Photoshop disasters said. It seems one gentleman, presumably the man powering the craft through the cool waters of the Caribbean, was surplus to the requirements of the newspaper, which removed from the image. All of him. The whole lot. Except his knee and lower leg.


text:
Special Consulting Services
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text:
Technology: The Great Growth Hope
By Michael Mandel
Every decade has its hot industries -- the ones that drive local growth and turn some cities into superstars. In the 1990s information technology was the main engine of prosperity, boosting incomes, creating new jobs, and sending real estate values soaring. Tech leaders such as San Jose, Calif., Seattle, and Austin, Tex., home of Dell Computer (DELL ), rode the wave. And even after the tech bubble burst, much of their gains still remained.
Now states and regions around the country, seeing their factory and back-office jobs slip away permanently to China and India, are hoping to emulate these winners. But rather than pinning all their hopes on trying to lure big factories -- like they might have in the past -- states like West Virgina, Florida, and Ohio are formulating plans to attract and encourage technologically innovative companies and industries.
Such reasoning is right on the mark. Innovation drove the New Economy, and it seems like a region's best hope for remaining economically relevant today. The U.S. still has a comparative advantage over its main competitors in education, technology, and the ability to finance and support risky and innovative startups.
There's a problem, though. Because of the unpredictable nature of technological change, relying on innovation as an economic-development strategy is far more risky than, say, trying to attract big manufacturing operations. If a state offers big incentives to Toyota (TM ) or Mercedes-Benz (DCX ) to get them to set up a new car plant, it most assuredly gets a factory that produces motor vehicles and employs a lot of workers.
It's very hard, however, to guess what the next big growth sector is going to be. That's the fundamental nature of innovation. No one guessed in the early 1990s that info tech was going to be able to lift local economies the way that it did. In 1994 the San Jose Mercury News, for example, published an article that was pessimistic about Silicon Valley's prospects, forecasting that the local economy would "slog along throughout most of the decade as firms continue to expand elsewhere."
Similarly, in the early 1990s the "Massachusetts Miracle" seemed to be over, as outfits such as Data General, Prime Computer, and Digital Equipment laid off hundreds of thousands of employees. And in Seattle, who knew that tiny Microsoft (MSFT ), which employed a paltry 15,000 workers globally in 1994, was going to end up being as economically important -- let alone more so -- for the region than Boeing (BA ), with a workforce then of 115,000. (In 2001, Boeing moved its corporate headquarters to Chicago.)
However, while the risks of an innovation-driven economic-development strategy may be greater, so are the potential rewards. The key is for regions to diversify their bets as much as possible.
Several technology areas have the potential for driving local growth. These include telecom, biotech, energy, nanotech, and space, each with its own positives and negatives. With biotech, the advantage is that the first biotech drug was developed more than 20 years ago, implying that the technology is maturing. But the disadvantage is that drug-approval process is necessarily a lengthy one.
Or take nanotech, which covers a range of new technologies, all of which have to do with building new materials up from individual atoms for a variety of purposes. Nanotech can potentially revolutionize manufacturing -- which in many industries has been technologically stagnant -- and thus help stem or even reverse the massive outflow of factory jobs. The problem, though, is that nanotech is still in the very early stages, meaning that it's very high-risk.
In addition to investing in a range of technologies, regions should also spend on the crucial inputs for innovation. Education is a key area. According to one economic study, workers in metropolitan areas with a higher percentage of college graduates get higher wages compared to similar workers elsewhere.
Another essential ingredient is finance -- in particular, the sorts of risk capital that new and growing companies need. The track record of government-backed venture-capital operations isn't particularly promising, since the choices have often been motivated more by politics than viability. Moreover, public agencies often have difficulty coping with the sheer uncertainty of innovation and the fact that most new businesses fail. Nevertheless, finance is so important for innovation that some sort of government action is probably needed to improve the flow of money to innovative startups.
Trying to accelerate innovation's progress in a region can be difficult and frustrating. But the potential payoffs are big -- and in the end, it's the only game in town.
Mandel is BusinessWeek's chief economist
Edited by Patricia O'Connell


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ARCADIA, Calif. (AP) -- Street Icon won the $58,000 feature for 3-year-olds by three-quarters of a length at Santa Anita on Thursday.
Ridden by Corey Nakatani, Street Icon ran 6 1/2 furlongs on the hillside turf course in 1:11.76 and paid $6.20, $4.20 and $2.60.
Gangnam guy returned $11.20 and $5, while 6-5 favorite Toowindytohaulrox was another three-quarters of a length back in third and paid $2.40 to show.
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text: Politics 4 March 2010 Steve Dyson gets misty-eyed reading a proper evening newspaper - the Evening Standard Standard has potential to turn a profit in his three-year game plan. Sign up for our weekly email * Former Birmingham Mail editor Steve Dyson gets quite misty-eyed today reviewing the free Evening Standard on his round-Britain blog of regional newspaper reviews over on Holdthefrontpage. Its devotion to proper, on-the-day, breaking news sees Dyson "greedily devouring the Standard from back to front" and saying "despite its switch in ownership, the Evening Standard is currently still a great paper, an important part of London's heritage and one the nation needs to shout much louder about wanting to keep at this level". There are 600,000-plus copies a night of the Standard currently flying off the distribution racks (without the need, sadly, for many of its network of vendors who seem to have largely disappeared). It must represent an awesome vehicle for advertisers, targeting - as it does - the most affluent and influential newspaper reading audience in the UK. If owner Alexander Lebedev can hold his nerve, and keep up the editorial quality of the Standard, I'd put money it turning a healthy profit well within his three-year game-plan. It is a far superior product to the two free newspapers -- London Lite and thelondonpaper -- which it has seen off against all odds. And Steve's right, we should rejoice in it. Taken from Press Gazette: http://blogs.pressgazette.co.uk/wire/6225. Dominic Ponsford is editor of Press Gazette Subscribe from just £1 per issue More


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Architectures, Bangkok, Culture, Historical Sites, Nature, Photographs, Thailand, Travels
Weekend Photo #16 : Reflections
Ancient City, Muang Boran. Gateway to Thailand's Cultural Heritage.September 12, 2010
Ancient City, Muang Boran. Gateway to Thailand's Cultural Heritage.September 12, 2010
His feature is striking, he seems calling my name. Perhaps he's lonely. He needs a company to cheer him up.August 14, 2010
Plunge into a summer cool break not far away from Manila.May 29, 2010
I miss the old lake, a portrait where my childhood was painted and sea shells flourished.May 23, 2010
Taken just before Sunset, a trek over the sea cliff and a magnificent white rock formation.May 9, 2010
Going Turkish in Dubai.April 25, 2010
Shhh… there's some secret in Tagaytay.April 11, 2010
Up, Up and Away.April 4, 2010
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There are so many exciting things happening in businesses in Iowa and around the world. The world of business is constantly evolving and we are committed to offering high quality education in a way that prepares students for their real-world experiences. We pay attention to industry trends and the needs of our students. Graduates of the Iowa State University College of Business become involved in student organizations, study abroad, participate in internships all over the country, and go on to work in some of the most amazing places.
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[VIDEO PICK: Off the Post] David Hovorka took his first touch with his tuchus and it was enough to beat Meteorem's goalkeeper in Sparta Prague B's 3-0 win.
This butt goal was no accident. Hovorka adjusted his body just right for a rear strike as he leaped into the cross.


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What is in this article?:
- On the Journey to a Smart Manufacturing Revolution
- Catalysts Driving Smart Manufacturing
- Next Steps to Ubiquitous Smart Manufacturing
A convergence of emerging technologies and process improvement initiatives has the potential to radically improve the way manufacturers thread processes and systems in the entire product value chain in order to deliver more options and new service models to customers.
More About:
In the 1970s and 80s, we witnessed a revolutionary wave of productivity improvements in manufacturing. New technologies, including personal computers (PCs), numerically controlled (NC) machines, programmable logic controllers (PLCs), and computer-aided manufacturing (CAM), combined with new process improvement ideas like Total Quality Management (TQM), Just-In-Time, and Six Sigma yielded great new levels of productivity and efficiency in many manufacturing industries.
Now, in this decade, we are seeing a similar convergence of technologies and process improvement initiatives with the potential to radically improve the way manufacturers thread processes and systems in the entire product value chain in order to deliver more options and new service models to customers.
Several organizations that bring together manufacturers, technologies and information systems, organizations like MESA (Manufacturing Enterprise Systems Association), the Industrial Internet Consortium (IIC), and the Smart Manufacturing Leadership Coalition (SMLC), are working on initiatives including the Industrial Internet of Things (IIoT) and Smart Manufacturing to coordinate this convergence of technologies and realize the process improvement potential sooner rather than later.
Smart Manufacturing is an initiative to bring about a revolution in manufacturing business strategy, turning traditional factories from cost centers into profitable innovation centers, through the integration of industrial automation, IIoT, and information technology (IT) including cloud services, 3D models, mobile computing, intelligence, and integration platforms.
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|Tweet Topic Started: Jan 4 2013, 09:27 AM (475 Views)
|Jan 4 2013, 09:27 AM Post #1
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|Jan 6 2013, 01:19 PM Post #2
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any ideas of lures that catch as well as the got-cha plug?
that will catch Spanish and blues off piers or other elevated spots
bucktail jigs
jighead and grub
any other ideas?
As versitile and as many different species as a gotcha catches,I'll stick with the real deal...
Nothing, absolutely nothing, catches blues and spanish like a Got-Cha. Why mess with perfection?
Clark Spoons work great down here in Florida as well. As a matter of fact many anglers prefer a Clark Spoon over a Gotcha Plug especially from an elevated pier, jetty, bridge.
A good technique is to tie a small egg or barrel sinker above a swivel and have the spoon trailing on about three feet of leader. The weight gets the spoon down in the water column a bit while retrieving from the higher elevation.
However, a Gotcha Plug is still a go to lure down here as well.
Let me know if you find something cheaper that works better.
You've used tree rigs haven't you? Slow them down a bit and you'll usually find a few small blues.
Three packs in Southport are about $9.00 but it's still a deal considering the amount of fish it can yield.
Bluefish--Trust me I've caught many a Spanish mackerel, bluefish, and bonito with a Clark Spoon in that fashion. It definitely works and is highly effective. It's a very popular technique down here in Florida on both coasts.
find gotchas all day here under three bucks. up til last year when one shop closed near MHC their price was 2.15 for a long time. dunno how much cheaper ya can get.
the remakes like the tsunami gotcha imitations dont work good in the water.
always have a half dozen of the small, and a handful of MAG gotchas in the boat bag...never know..
Clark spoons work really well on the Troll they also work casting.A small 1 oz trolling weight usually makes them even more effective.As soon as the water reaches 72 degrees we start to catch the Spanish.We caught about 2300 Spanish on a Clark spoon this season. Alot of them were caught less than 40 yards away from the Sandbridge and Virginia Beach piers.A cheep alternative would be to pour your own 1 oz trolling weights and smash them in a vise afterwards put a snap ring on one end with a treble hook,spray paint them gold,silver,red,white or chartreuse.
I like Gotchas but I've been catching Spanish and blues with Clarks for as long as I can remember. I always trolled with them but I'm gonna try that trolling lead and casting idea a couple of you mentioned.
I make my own Gotchas from old BIC pen barrels.
Some wire, a couple of treble hooks and a homemade lead head. A swivel on the front end and a dab of paint. C2
any one ever try a straw rig?
Yep we make them out of drinking straws,coffee stir sitcks,heat shrink tubing and other fly making materials.
i hate gotcha plugs..catch plenty fish..but dont like the jiggin part..i use stingsilvers...and catch as many as anyone around me
If you already have some Clarkspoons try out the Clarkspoon caster.


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Gallery: Bcl10 (C78F1) Rabbit mAb #4237
Western Blotting Protocol
For western blots, incubate membrane with diluted primary antibody in 5% w/v BSA, 1X TBS, 0.1% Tween® 20 at 4°C with gentle shaking, overnight.
NOTE: Please refer to primary antibody datasheet or product webpage for recommended antibody dilution.
A. Solutions and Reagents
From sample preparation to detection, the reagents you need for your Western Blot are now in one convenient kit: #12957 Western Blotting Application Solutions Kit
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.
- 20X Phosphate Buffered Saline (PBS): (#9808) To prepare 1 L 1X PBS: add 50 ml 20X PBS to 950 ml dH2O, mix.
- 10X Tris Buffered Saline (TBS): (#12498) To prepare 1 L 1X TBS: add 100 ml 10X to 900 ml dH2O, mix.
- 1X SDS Sample Buffer: Blue Loading Pack (#7722) or Red Loading Pack (#7723) Prepare fresh 3X reducing loading buffer by adding 1/10 volume 30X DTT to 1 volume of 3X SDS loading buffer. Dilute to 1X with dH2O.
- 10X Tris-Glycine SDS Running Buffer: (#4050) To prepare 1 L 1X running buffer: add 100 ml 10X running buffer to 900 ml dH2O, mix.
- 10X Tris-Glycine Transfer Buffer: (#12539) To prepare 1 L 1X Transfer Buffer: add 100 ml 10X Transfer Buffer to 200 ml methanol + 700 ml dH2O, mix.
- 10X Tris Buffered Saline with Tween® 20 (TBST): (#9997) To prepare 1 L 1X TBST: add 100 ml 10X TBST to 900 ml dH2O, mix.
- Nonfat Dry Milk: (#9999).
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- Bovine Serum Albumin (BSA): (#9998).
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- Biotinylated Protein Ladder Detection Pack: (#7727).
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NOTE: Volumes are for 10 cm x 10 cm (100 cm2) of membrane; for different sized membranes, adjust volumes accordingly.
I. Membrane Blocking
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- Wash three times for 5 min each with 15 ml of TBST.
II. Primary Antibody Incubation
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- Wash three times for 5 min each with 15 ml of TBST.
- Proceed with detection (Section D).
D. Detection of Proteins
Directions for Use:
- Wash membrane-bound HRP (antibody conjugate) three times for 5 minutes in TBST.
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- Incubate substrate with membrane for 1 minute, remove excess solution (membrane remains wet), wrap in plastic and expose to X-ray film.
* Avoid repeated exposure to skin.
posted June 2005
revised November 2013
Western Blot Reprobing Protocol
Reprobing of an existing membrane is a convenient means to immunoblot for multiple proteins independently when only a limited amount of sample is available. It should be noted that for the best possible results a fresh blot is always recommended. Reprobing can be a valuable method but with each reprobing of a blot there is potential for increased background signal. Additionally, it is recommended that you verify the removal of the first antibody complex prior to reprobing so that signal attributed to binding of the new antibody is not leftover signal from the first immunoblotting experiment. This can be done by re-exposing the blot to ECL reagents and making sure there is no signal prior to adding the next primary antibody.
A. Solutions and Reagents
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalently purified water.
- Wash Buffer: Tris Buffered Saline with Tween® 20 (TBST-10X) (#9997)
- Stripping Buffer: To prepare 100 ml, mix 6.25 ml of 1M Tris-HCl pH 6.8, 10 ml of 20% SDS and 700 μl β-mercaptoethanol. Bring to 100 ml with deionized H20. Make buffer fresh just prior to use.
B. Protocol
- After film exposure, wash membrane four times for 5 min each in TBST. Best results are obtained if the membrane is not allowed to dry.
- Incubate membrane for 30 min at 50°C in stripping buffer (with slight agitation).
- Wash membrane six times for 5 min each in TBST.
- (Optional) To assure that the original signal is removed, wash membrane twice for 5 min each with 10 ml of TBST. Incubate membrane with LumiGLO® with gentle agitation for 1 min at room temperature. Drain membrane of excess developing solution. Do not let dry. Wrap in plastic wrap and expose to x-ray film.
- Wash membrane again four times for 5 min each in TBST.
- The membrane is now ready to reuse. Start detection at the "Membrane Blocking and Antibody Incubations" step in the Western Immunoblotting Protocol.
posted June 2005
revised October 2016
Immunoprecipitation for Native Proteins
This protocol is intended for immunoprecipitation of native proteins for analysis by western immunoblot or kinase activity.
A. Solutions and Reagents
NOTE: Prepare solutions with reverse osmosis deionized (RODI) or equivalent grade water.
- 20X Phosphate Buffered Saline (PBS): (#9808) To prepare 1 L of 1X PBS, add 50 ml 20X PBS to 950 ml dH2O, mix.
10X Cell Lysis Buffer: (#9803) To prepare 10 ml of 1X cell lysis buffer, add 1 ml cell lysis buffer to 9 ml dH2O, mix.
NOTE: Add 1 mM PMSF (#8553) immediately prior to use.
- 3X SDS Sample Buffer: Blue Loading Pack (#7722) or Red Loading Pack (#7723) Prepare fresh 3X reducing loading buffer by adding 1/10 volume 30X DTT to 1 volume of 3X SDS loading buffer.
- Protein A Magnetic Beads: Use Protein A (#8687) for rabbit IgG immunoprecipitation.
- 6-Tube Magnetic Separation Rack: (#7017).
- 10X Kinase Buffer (for kinase assays): (#9802) To Prepare 1 ml of 1X kinase buffer, add 100 µl 10X kinase buffer to 900 µl dH2O, mix.
- ATP (10 mM) (for kinase assays): (#9804) To prepare 0.5 ml of ATP (200 µM), add 10 µl ATP (10 mM) to 490 µl 1X kinase buffer.
B. Preparing Cell Lysates
- Aspirate media. Treat cells by adding fresh media containing regulator for desired time.
- To harvest cells under nondenaturing conditions, remove media and rinse cells once with ice-cold 1X PBS.
- Remove PBS and add 0.5 ml ice-cold 1X cell lysis buffer to each plate (10 cm) and incubate on ice for 5 min.
- Scrape cells off the plate and transfer to microcentrifuge tubes. Keep on ice.
- Sonicate on ice three times for 5 sec each.
- Microcentrifuge for 10 min at 4°C, 14,000 x g and transfer the supernatant to a new tube. The supernatant is the cell lysate. If necessary, lysate can be stored at -80°C.
C. Immunoprecipitation
Cell Lysate Pre-Clearing (Optional)
- Vortex to mix beads.
- Add 10-30 µl of 50% Protein A magnetic bead slurry of to 200 µl cell lysate at 1 mg/ml.
- Incubate with rotation at 4°C for 30-60 min.
- Pellet beads using magnetic separation rack. Transfer the supernatant to a fresh tube.
- Proceed to immunoprecipitation below.
- Add primary antibody (at the appropriate dilution as recommended in the product datasheet) to 200 µl cell lysate at 1 mg/ml. Incubate with rotation overnight at 4°C.
- Add protein A magnetic beads (10-30 µl of 50% bead slurry). Incubate with rotation for 10-30 min at 4°C.
- Pellet beads using magnetic separation rack. Wash pellet five times with 500 µl of 1X cell lysis buffer. Keep on ice between washes.
- Proceed to analyze by western immunoblotting or kinase activity (section D).
D. Sample Analysis
Proceed to one of the following specific set of steps.
For Analysis by Western Immunoblotting
- Resuspend the pellet with 20 µl 3X SDS sample buffer. Vortex, then microcentrifuge for 30 sec at 14,000 x g.
- Heat the sample to 95-100°C for 2-5 min and microcentrifuge for 1 min at 14,000 x g.
- Load the sample (15-30 µl) on a 4-20% gel for SDS-PAGE.
- Analyze sample by western blot (see Western Immunoblotting Protocol).
NOTE: To minimize masking caused by denatured IgG heavy chains (~50 kDa), we recommend using Mouse Anti-Rabbit IgG (Light-Chain Specific) (L57A3) mAb (#3677) or Mouse Anti-Rabbit IgG (Conformation Specific) (L27A9) mAb (#3678) (or HRP conjugate #5127). To minimize masking caused by denatured IgG light chains (~25 kDa), we recommend using Mouse Anti-Rabbit IgG (Conformation Specific) (L27A9) mAb (#3678) (or HRP conjugate #5127).
For Analysis by Kinase Assay
- Wash pellet twice with 500 µl 1X kinase buffer. Keep on ice.
- Suspend pellet in 40 µl 1X kinase buffer supplemented with 200 µM ATP and appropriate substrate.
- Incubate for 30 min at 30°C.
- Terminate reaction with 20 µl 3X SDS sample buffer. Vortex, then microcentrifuge for 30 sec.
- Transfer supernatant containing phosphorylated substrate to another tube.
- Heat the sample to 95-100°C for 2-5 min and microcentrifuge for 1 min at 14,000 x g.
- Load the sample (15-30 µl) on SDS-PAGE (4-20%).
posted December 2008
revised November 2013
|Western Blotting
Bcl10 (C78F1) Rabbit mAb detects endogenous levels of total Bcl10 protein.Species Reactivity: Human, Mouse, Rat Species predicted to react based on 100% sequence homology: Monkey
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Ser60 of Bcl10.
Bcl10/CIPER/CLAP/mE10 is a widely expressed CARD (caspase recruitment domain) containing protein shown to induce apoptosis and activate NF-κB (1-5). The CARD domain mediates self-oligomerization, interactions with other CARD proteins and is necessary for NF-κB activation, although the precise mechanism which Bcl10 regulates these processes is not fully understood. The discovery of Bcl10 came from observations of the chromosomal translocation t(1;14)(p22;q32) from B cell lymphomas of the mucosa-associated lymphoid tissue (MALT) (1,5). This translocation results in deregulated expression of a truncated form of Bcl10 which lacks apoptotic activity and enhances transformation. Studies from Bcl10 deficient mice demonstrate that Bcl10 is essential for the activation of NF-κB by T- and B-cell receptors (6). One third of Bcl10 deficient mice developed lethal exencephaly. Surviving mice were unaffected by various apoptotic stimuli, but were severely immunodeficient and defective in antigen receptor-induced NF-κB activiation. PKC or T-cell receptor signaling results in a downregulation of Bcl10 protein levels, attenuating both NF-κB activation and cellular proliferation and also provides a negative feedback regulation of the NF-κB signaling to T cell signaling (7).
1. Willis, T. G. et al. (1999) Cell 96, 35-45.
2. Koseki, T. et al. (1999) J. Biol. Chem. 274, 9955-9961.
3. Srinivasula, S. M. et al. (1999) J. Biol. Chem. 274, 17946-17954.
4. Yan, M. et al. (1999) J. Biol. Chem. 274, 10287-10292.
5. Zhang, Q. et al. (1999) Nature Genetics 22, 63-68.
6. Ruland, J. et al. (2001) Cell 104, 33-42.
7. Scharschmidt, E. et al. (2004) Mol. Cell. Biol. 24, 3860-3873.
For Research Use Only. Not For Use In Diagnostic Procedures. Cell Signaling Technology is a trademark of Cell Signaling Technology, Inc. U.S. Patent No. 5,675,063.


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This is a special expanded article, covering both December and the full year 2011.
12 deals were priced in December and the calendar ended abruptly about a week before the holiday season began in earnest. Except for one company that braved late December, it felt to most like a too-early holiday.
There were 19 new filings during December so the pipeline remains healthy. Some notable ones include Proofpoint, AVAST Software (Information Security) and Tumi (high-end luggage and accessories).
Eight deals were withdrawn in December. That's about double the usual number. Many of these had unusual teams of underwriters and faced a critical market. Seemed like they wanted to go back to the drawing board.
As we gear up for 2012 the IPO outlook is decent. The pipeline is there and market conditions are generally supportive, at least for quality companies. It probably will not be a smooth ride, though. Europe remains mired in reform battles and still has growth and debt problems. The US seems to be muddling through, but 2012 is an election year. Our best guess is that Obama wins a second term but along the way there are likely to be programs, proposals and rhetoric that can move markets. (We have no political affiliation and our Obama guess is based on fairly reliable long- term precedent.)
First let's look at the month of December and then examine overall performance for the class of 2011 and also the rest of our IPO ecosystem.
December Performance
December was another tough month, with the average stock down 4%. Combined with the 6% drop in November the October gains are gone. The top 10 names were up 15% and the bottom 10 were down 29%. December didn't bring much cheer.
The best performer was Imperva (NYSE:IMPV), a hot new IPO in Information Security. That success is likely to spur even more filings in the space.
NetSpend (NASDAQ:NTSP) rebounds as kind of a "poor man's Green Dot" within the consumer finance sector. Envestnet (NYSE:ENV) is an interesting potential on "break away advisors" which is the trend in asset management.
Tax loss selling appears to have driven the loser list. All those names are down big for the year and worth more dead than alive in many portfolios.
December was a short, low-volume month. We should get some better price direction signals in January.
In terms of our class of 2011, the average deal is down 13% from where it priced. (Remember we track only growth names and avoid banking, REIT stocks, and commodities.) Only 20 deals are trading above their IPO price!
Three of the top names are technology driven stories (Imperva, InvenSense & Fusion-io (NYSE:FIO)) and two are more traditional opportunities in large markets. We've been a fan of InvenSense since the beginning and we are covering them in RealVR practice.
Moving on to the dogs, the near-total loss of FriendFinder (FFN) should close the door for all adult-oriented content companies in the public markets. Nobody wants to own this stuff even when it's disguised as "adult social networking."
China was a big theme turned flash in the pan due to widespread accounting irregularities and so-so management. Most institutions avoided these names anyway.
Finally, semiconductors remain a challenging business due to the long cycle times, high investment levels and cutthroat pricing.
Turning to the pre-2011 IPO class, the performance was sobering there as well. Only 18 companies were positive for the year and the average loss was 29%!
There's no sure way to make money in the IPO market but it would appear that a good way to lose money would be to try and find winners among the losers. Winners can have corrections but so far there have been few, if any, real turnarounds.
At the top of the pre-2011 we find e-commerce infrastructure player SPS Commerce. The company was up 53% in 2011 and exceeded our IV estimate.
Other winners were Accretive Health (+50%), SolarWinds (+45%), Convio (+31%), and SodaStream (+25%).
The big losers have appeared frequently in our monthly losers table so the names are familiar: Motricity (-95%), SemiLEDS (-88%), Camelot Info (- 88%), Ming Yang Wind (-82%) and Pacific Bio (- 81%).
We've included additional tables in the back of this report showing all the performance details along with the usual overview and pipeline spreadsheets.
IPO Candy Folio Update
The IPO Candy Folio continued to languish with the market and was down 1.73% in December. For the year the folio was down 24.87% versus a decline of only 5.45% in the Russell 2000.
The first big discovery we made was that the lack of hedging in the Folio forced it to suffer large losses in July and August that were at least partially avoidable. Unfortunately, there is little we can do about this. We may try bringing in some inverse ETF names in 2012 as a test.
The other big change we made (supported by the performance data above) was to shift to more concentrated positions. We didn't do this until the middle of Q4 but we eliminated many names and concentrated our holdings more. [See the last Candygram for a list of the changes.]
Today there are 26 positions in the Folio and we have 21% in cash. After the November house cleaning we feel that the portfolio is solid. Some minor adjustments are planned for January and we may begin to experiment with some hedging techniques.
More information and disclosures regarding the IPO Candy Folio can be found at: ipocandy.com/invest.
The Pipeline
We've updated the pipeline for new filings and priced deals. The total stands at about 130 deals.
No word yet on the big Facebook IPO but the market will be eagerly awaiting it.
Coverage And The Calendar
This month we will see banker coverage for the few deals that priced in December – Jive Software, Michael Kors and Zynga. Zynga stands to get the best boost from coverage since JIVE and KORS are up over 30% from their IPO prices.
Lockups coming off this month include Zillow, Skullcandy, Francescas, Dunkin Brands, Tangoe, Horizon Pharma, Chefs Warehouse and Teavana.
Disclosure: I have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours.


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The #Takeoff series is about crowdsourcing issues important to Canadian small businesses. They tell us about their defining moments and we write about their stories, the issues, and strategies for success or how to overcome obstacles.
In 2010, entrepreneur Christopher Thierry hired a CEO to run Etelesolv Inc., his Montreal-based software startup that had stalled and was bleeding cash because of the recession.
The new hire, experienced with an advanced degree, was supposed to be the "silver bullet" that would save the company, which had developed a platform for corporations to manage telecom and IT expenses. The chief executive officer was to start on a Monday morning and Mr. Thierry had an important meeting set up for them to pitch their product, TeleManager, to a Toronto bank.
On Sunday night he got a call saying the new CEO had accepted an offer with another company.
Mr. Thierry had a horrible night, and then he had an epiphany. He was going to learn how to run the company.
"I was in this mode of really doubting everything I was doing," he says. "But I realized, this is my mess, I've got to clean it up. I have my house on the line."
Robert Simon, managing partner with the IT Venture Fund at the Business Development Bank of Canada, said it was a good move.
"Christopher did the right thing, he jumped back in," Mr. Simon said. "As outside board members and investors, we prefer that the founder continue to make the transition because they are so personally invested in the success of the business."
This is especially true, he adds, when the business in the $10-million to $20-million revenue range. Important ingredients for success are the willingness to listen and learn from mentors, coaches and other executives.
This is exactly what Mr. Thierry did.
Then in his early 30s, he knew he was much better at starting things than running them. So he embarked on a journey to reinvent himself. He enrolled in the Entrepreneurial Masters Program run by the Entrepreneurs' Organization, which was being hosted by MIT.
The book that became his bible was Mastering the Rockefeller Habits by management guru Verne Harnish, one of the organization's founders.
"There was a checklist — 30 things great companies do," Mr. Thierry said. "I had three of them, and that was a real eye-opener. I realized how many things I was not doing. I was just scrambling for survival."
He learned that he had to lift his head up out of the daily grind and begin to think strategically, to focus on long-term growth, rather than simply making money short term. And he had to carefully consider if he had the right management team in place to make the plan work.
When he got back from his first session and started talking about core values, messaging and creating culture, he ran into a "brick wall."
"The team had been there putting out fires. They said, 'Let's not waste our time figuring this stuff out. Let's get out there and let's make some money. Let's sell!' "
He realized that he had to educate his team and make some tough choices about who was on it. He eventually fired one of his key managers who did not share the vision and has since been more careful about hiring people who fit in.
Mr. Thierry learned that to create the kind of cohesive and growth-oriented culture he envisaged, he would have to learn how to communicate better with his employees.
He found help in the writings of Vancouver-based CEO coach and entrepreneur Cameron Herold.
"Culture is the glue that aligns," explains Mr. Herold. "Culture is about the buzz, the feeling, the core purpose, the core values – bringing in more and more people who 'get it' and 'live it.' "
Mr. Thierry introduced an exercise designed by Mr. Herold called A Painted Picture, which asked staff to envisage where the company would be in three years. It inspired them without creating pressure by demanding immediate results, he says.
One recent example that put Mr. Thierry's communication skills to the test involved helping salespeople understand that they might make less money this year because of plans to launch a new product that would boost business in 2015.
Three years after the first exercise, Mr. Thierry is amazed by what has been accomplished. The company has rolled out the new product – called Cimpl – which is more user friendly and designed to provide a more global reach. Etelesolv is on track to have 100 employees this year, he says, and revenue is in the $5-million to $10-million range. And the company is profitable.
"But even revenue, for the most part, is secondary to vision," Mr. Thierry says. "We want to create recurring value, take a dramatic leap and get way ahead of our competition."
He says his transition was a "humbling experience."
"When I started focusing in on direction and strategy and culture, it crystallized my job and I stopped running around doing all the little things. I started to trust my team. People were getting it and they were following through. At a certain point you can't hold on to things."
And that includes being in charge. Eventually, he says, he might need to fire himself and try again to find someone else to run the company.
That's a valuable way of thinking, according to Tony Ritlop, partner with Ernst & Young's Advisory Services.
"Entrepreneurs often make the transition to CEO – but not always successfully," he says. "Those entrepreneurs who do make a successful transition have extraordinary drive, ambition, energy and ideas. Most importantly, though, they surround themselves with people who are capable of filling the gaps they cannot – and then they empower those people to bring in new ideas and make decisions.
"In some cases, great entrepreneurs know when not to become the CEO, because they recognize they lack some of the required skills. In those cases, they might become chairperson of the board and still influence decisions, but leave the day-to-day running of the business to professional managers."
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Reactions to tighter hurricane intensity/SST link
There was another twist to the hurricanes/global warming issue in Science Express on Friday where a new paper from the Webster/Curry team just appeared. This study, lead by Carlos Hoyos, crosses a few t's and dots a couple of i's on the connection of increasing numbers of intense hurricanes (Cat. 4 and 5) to sea surface temperatures (SST). Basically, they looked at a number of other key variables for hurricane intensity (like wind shear and humidity) and examined whether there was any pattern to those variables across the different ocean basins that they study. Bottom line? None of the other variables have as much explanatory power for the long term trends as SST which is the only consistently trending constituent in the mix. So far, so un-surprising. However, one interesting aspect of this story is that almost all the key players in the ongoing debate were interviewed by different journalists in various media and those comments are probably more useful for gauging the state of play than the details of the new paper itself.
First off, Chris Landsea, a serious researcher in the 'dissenting' camp, in the WSJ story (reprinted here) and in a Newsday article is quoted as saying that the data (particularly from the early 70s and the Northern Indian Ocean) aren't good enough to come to these conclusions. However, Curry riposts that for the doubling of Cat 4 + Cat 5 storms to be an artefact, half the Cat 1 + Cat 2 storms in the early records would have had to have been mis-classified Cat 4 storms instead and she thinks that unlikely. More oddly, Landsea also makes the point that the sensitivity of the hurricane intensity disagrees with model predictions and theory. This is odd, not because it's not true (and is the principle reason why the attribution of more intense hurricanes to GW is not yet set in stone), but because Landsea has previously been much more of a champion of favoring observations over modelling.
In the same National Geographic piece, Roger Pielke Jr. is broadly supportive and makes his standard comment that the increasing damages from hurricanes is mostly related to increased development rather than changes in intensity, but that obviously, future potential increases in intensity will be an additional factor.
Fox News interviewed Kerry Emanuel (author of a related study last year, which was slightly modified following comments by Landsea in Nature), who is also unsurprised that the longer term trends are related to SSTs and not to any of the other factors. Kevin Trenberth (also in the Fox News piece) made a good point though. The authors of the study used the NCEP reanalysis as the source of their data. A reanalysis is a re-running of the current state-of-the-art weather forecasting model for all the sources of data that were available in the past (i.e. a hindcast of what all the 6 hour weather forecasts would have been if they had used today's model). These projects (and there are two main ones – NCEP and ERA-40) have a problem in that the amount of useful data increases as you go along – most significantly around 1979 when satellite data starts to be significant. So estimates of key quantities are likely to be worse prior to 1979. Not mentioned, but conceivably important is that the NCEP reanalysis is tied in some respects to the radiosonde data, which, as we discussed last year, may have some spurious trends. This doesn't obviously affect the results significantly, but it does suggest that doing the analyses again using the ERA-40 data might be a useful check.
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True Seekers Deluxe Video on Demand Package – $19.99
This is a special deluxe package designed for the TRUE SEEKERS! Be sure to gift the package to 2 friends and help spread the word. More info
(Click here if you want to order just the film on demand. Ahora disponible en español!)
If you are new to "on demand", having trouble downloading or viewing the film, check out the frequently asked questions.
'TIME IS ART' feature film (88 min) + BONUS SCENES AND ADDITIONAL CONTENT:
– Interview with Simon G. Powell "Synchronicity and Self-Organization" (21 min)
– Bonus scene with Jill Purce "Voice as a Spiritual Medium" (13 min)
– Bonus scene with Rupert Sheldrake "Synchronicity & Telepathy" (23 min)
– Bonus scene with Nina Elshof "Power Places" (12 min)
– Extended scene with Graham Hancock (19 min)
– Also includes the original film soundtrack (http://thesyncmovie.com/soundtrack/)
TRUE SEEKERS Deluxe Package on Blu-ray & DVD
High Definition movie + bonus scenes and interviews with Simon G. Powell, Jill Purce, Nina Elshof, Graham Hancock and Rupert Sheldrake.
DVD + True Seekers 'On Demand' Package / $25
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Does not include bonus scenes
Original Film Soundtrack – $12
1. Something Fiction – Lucid Dream Machine (Spud Crowley's Glass Realm Remix)
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3. Dream Circle – Dark Star
4. Bachan Kaur – Luz del Bosque
5. Diana Zinni – Kill the Hope
6. It's Not Night It's Space – The Gathering
7. WāKEN – Shamanista (Feat. Betty Kay)
8. Dream Circle – The Medicine Man
9. East Forest – Pendulum
10. Diana Zinni – The Moon
11. Dream Circle – So Many Things
12. East Forest – Carry Water
COMING SOON! 'Time is Art' the Book
The film has inspired the book of the same name and includes in depth conversations with people featured in the film + additional scholars such as Stephanie South as well as writings and poetry by Jennifer Palmer. Also includes artwork from artists featured in the film.
THANK YOU for supporting this conscious raising film!


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Anna PurDia Model
Aimee MaeModel Female PRATHER, California, US
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About Me
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Have you worked with Aimee Mae? Add Credits for Aimee Mae! >>
Credit Notes
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36 yrs old, braces 12+ years no breaks. Recent months my orthodontist began closing a large space, I asked him if the lips drooping over my top teeth is due to closing of the space, he said no because he had not moved my teeth up nor down in a long time. Also, side teeth are less visible. I have had temp filler hylauralic acid injected in my lips many times in the past, but nothing since 2008 because for some reason, they maintained their fullness. But why? Is this related to my recent problem?
Please see update posted here.


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Myoglobin/gold nanoparticles/carbon spheres 3-D architecture for the fabrication of a novel biosensor
- First Online:
- Received:
- Revised:
- Accepted:
DOI: 10.1007/s12274-009-9019-6
- Cite this article as:
- Chen, X., Zhang, J.J., Xuan, J. et al. Nano Res. (2009) 2: 210. doi:10.1007/s12274-009-9019-6
- Citations
- 602 Downloads
A novel biosensor based on a myoglobin/gold nanoparticles/carbon spheres (Mb-AuNPs-CNs) 3-D architecture bioconjunction has been fabricated for the determination of hydrogen peroxide (H2O2). Cyclic voltammetry (CV), Fourier transform infrared (FT-IR) spectroscopy and scanning electron microscopy (SEM) were used to characterize the bioconjunction of the AuNPs-CNs with Mb. Experimental results demonstrate that the AuNPs-CNs hybrid material is more effective in facilitating electron transfer of the immobilized enzyme than CNs alone, which can be attributed to the unique nanostructure and larger surface area of the bioconjunction. The biosensor displayed good performance for the detection of H2O2 with a wide linear range from 0.28 μmol/L to 116.5 μmol/L and a detection limit of 0.12 μmol/L. The Michaelis-Menten constant KMapp value was estimated to be 0.3 mmol/L. The resulting biosensor exhibited fast amperometric response, and good stability, reproducibility, and selectivity to H2O2.