text:
View a PDF file of this information here
This is for 90 to 95% of patients
You will be up on your feet the same day of surgery and walking with the help of hospital staff (or the next day, if your surgery is late in the day.) Your hip may be swollen and warm. You will use ice and keep the leg elevated to help with the swelling. It is normal to have some swelling and warmth in the hip for up to eight months. It should, however, decrease gradually over time.
The hospital staff will help you work on your motion, strength and walking with the help of a walker.
You will be discharged from the hospital. For example: if you have surgery on Monday you will be discharged on Thursday. If your surgery is on Wednesday, you will be discharged Saturday. If your surgery is on Friday, you will be discharged on Monday. You will either go home from the hospital or to a rehabilitation center.
Continue with physical therapy. The physical therapy may be at a rehab center, in your home, or as outpatient therapy. You must work hard and be diligent about your exercises.
First post-op visit in the office. We will check your wound, swelling and motion. You will also have an x-ray this visit. You may begin hip abduction exercises, which we will show you in the office. These exercises involve activities such as stairs and strengthening the outside muscle of your hip to help bring your leg out to the side. By this time, you should be using a single cane.
You may return to driving if you are not taking pain pills. Make sure you practice first on a side street or parking lot to make sure that you can drive safely. You may feel safe enough to stop using the cane. You may use some lotion on the scar. You may use whatever kind of lotion that you like. Rub the scar up and down, side to side and in small circles. This will help the scar become less sensitive and help it fade.
You will walk with no cane and will feel your strength increasing and pain decreasing.
Most patients will have reached maximum strength and improvement.
Hiking, biking, walking, golf, doubles tennis, cross-country skiing (with care).


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Like The American Legion, Department of Maine on facebook
Click on Post Locator to Find an
American Legion Post
SMILE & latest Membership Report click here.
Get the latest free version of Acrobat Adobe Reader here:
The American Legion
Department of Maine
June 16-18, 2017
Spectacular Event Center
395 Griffin Road
Annual State Convention Agenda
Registration/Banquet/Installation Forms & Information
Dirigo Boys State
June 18-22, 2017
Thomas College
180 West River Rd.
Waterville, Maine 04901
The American Legion, Department of Maine is proud to announce its 70th Annual American Legion Dirigo Boys State program at Thomas College in Waterville during the week of June 18-22, 2017.
Click here for a copy of the 2017 Dirigo Boys State Announcement Brochure
For more questions and information, please or contact us via email at email@example.com; firstname.lastname@example.com or call Department Headquarters at 207-873-3229.
The American Legion
National Convention
August 18 - 24, 2017
Reno, Nevada
If you are interested in attending National Convention,
please click on the National Convention Housing Form and Information and follow proper instructions.
National Convention Housing Form and Information
MAY 2017 Issue
Click here for TML Archives
The American Legion, Department of Maine
100th Anniversary Members Directory
The American Legion, Department of Maine is working on its 100th Birthday Celebration. In order to make this a special event, we are offering all members the opportunity to be part of the history of our 100th Anniversary.
The American Legion, Department of Maine has partnered with PCI (also known as Publishing Concepts) to produce our new 100th Anniversary Members Directory. PCI is a company that publishes directories for educational institutions, fraternities, sororities and military organizations across the nation.
This hard-cover, yearbook style directory offers members of their survivors the opportunity for a permanent commemoration of the Legionnaires' Legion career, including a narrative and photographs. Participation is voluntary.
This benefits our organization in three ways:
1. It helps chronicle and commemorate our membership's Legion experiences as our Centennial celebration approaches.
2. Our directory will be analyzed and updated, completing missing information and removing outdated and/or incorrect information.
3. Our inactive members will be asked to participate and encouraged to renew their membership.
The names, addresses and information provided to PCI by The American Legion, Department of Maine for the publication of the Directory will be held confidential by PCI.
The Directory will be made available only to members of The American Legion, Department Maine. Upon completion of the project, PCI will return to The American Legion, Department of Maine any and all electronic files that have been supplied by The American Legion, Department of Maine or produced by PCI in connection with the production of the Directory.
Only members of The American Legion, Department of Maine may purchase this Directory.
The total duration of the Directory is about 12 months. Types of questions that will be asked are: Organization/Membership background, military Branch of Service, length of time, tour of duty and military awards with a short story to follow, status after the military, current job, are you retired, are you active within the American Legion, do you volunteer to work with Veterans or within the community and what was your greatest achievement in your post military career. You will also have the opportunity to provide a picture from the past or a current one.
PCI representatives will be requesting your participation at some point throughout the next year. In the meantime, those that do wish to participate can gather photographs and narratives they may wish to share.
Frequently Asked Questions
Charles Schmidt was elected national commander of The American Legion on Sept., 1, 2016, during the organization's 98th National Convention in Cincinnati, Ohio.
Click here to learn more about Charles Schmidt, or visit www.legion.org
Please click here to learn about National Commander Schmidt's Pin Incentive Program
National Commander's Incentive Pin Certification Form
Please click here to learn about National Commander's Honor Ribbon
National Commander's Honor Ribbon Form
Click here for Department of Maine Posts
Click here for District Meeting Dates
Please click here if you have already renewed your membership online and need to reprint another temporary membership card
Access to MyLegion is now open to all Legion Members and Post/Department Leaders.
MyLegion.org is a website designed to connect members of The American Legion to their Post and Department leadership, other veterans with similar interests, and the vast array of services offered at every level of the organization. Click here for more information and access to Mylegion.org.
Since its founding in 1922, USAA has been dedicated to helping those in military and their families. They have what you need to make it simple, including insurance, free financial advice, banking, investing, member discounts and shopping - all delivered according to our core values of honesty, integrity, loyalty and service. Click here to visit USAA website or call 1-877-699-2654.
Your valued status as a Legionnaire entitles you to LegionCare, up to $5,000.00 in NO COST benefits. But Confirmation is required for full activation.
$5,000.00 NO COST To You Accidental Death Protection if traveling on official American Legion business.
$1,000 Accident Protection for all covered accidents.
Legionnaires can sign up for the "No Cost" AD&D by visiting www.theLIT.com/no-cost-legioncare or by calling the toll free number 1-800-235-6943.
NEW: Click here and fill out the attached form. Email form to email@example.com or print a copy and mail to The American Legion, Department of Maine
5 Verti Drive, Winslow, Me. 04901
To learn more about Member Benefits, please click here.
As the war on terrorism continues, more young American military men and women are coming home bearing the scars of battle. Many continue to recover physically and emotionally from severe injuries including loss of limbs, mobility, and psychological trauma.
The American Legion and the Department of Defense have teamed up to provide these outstanding and dedicated Americans all the help they need to re-establish their lives when they come home.
It is a pillar of The American Legion- "to consecrate and sanctify our comradeship by our devotion to mutual helpfulness".
If your post has agreed to participate in the Heroes to Hometown program because a comrade is coming home to your community, download this guide and visit the National Heroes2Hometowns website. These resources will provide you with information you need to ensure that the servicemember and their family will get full assistance for a successful transition back to civilian life.
IRS Filing Requirement for All Posts/Units
Annual Electronic Filing Requirement for Small Exempt Organizations -- Form 990-N (e-Postcard)
Small tax-exempt organizations whose annual gross receipts are normally $25,000 or less may (will for The American Legion) be required to electronically submit Form 990-N, also known as the e-Postcard, unless they choose to file a complete Form 990 or Form 990-EZ.
If you do not file your e-Postcard on time, the IRS will send you a reminder notice but you will not be assessed a penalty for late filing the e-Postcard. However, an organization that fails to file required e-Postcards (or information returns - Forms 990 or 990-EZ) for three consecutive years will automatically lose its tax-exempt status. The revocation of the organization's tax-exempt status will not take place until the filing due date of the third year.
This filing requirement will be mandatory for all American Legion posts and units previously exempted because they did not meet the minimum income level of 25,000 to file a 990 or 990-EZ.
Due Date of the e-Postcard:
The e-Postcard is due every year by the 15th day of the 5th month after the close of your tax year. For example, if your tax year ended on December 31, the e-Postcard is due May 15 of the following year. You cannot file the e-Postcard until after your tax year ends.
Military Discharge Requests
If you are a veteran whose home of record at time of entry into the service was the State of Maine then a copy of your DD-214 (or equivalent) may be on file at the Bureau of Veteran's Services.
Please click on the Application Request for Military Discharge link below if you are requesting a discharge from the State of Maine and mail application to the Bureau of Veteran's Services for processing. For more information, please visit www.maine.gov/dvem/bvs/military_discharges.htm
Application Request for Military Discharge
The National Personnel Records Center (NPRC) has provided the following website for veterans to gain access to their DD-214s
online: http://vetrecs.archives.gov
This may be particularly helpful when a veteran needs a copy of his DD-214 for employment purposes. NPRC is working to make it easier for veterans with computers and Internet access to obtain copies of documents from their military files.
Military veterans and the next of kin of deceased former military members may now use a new online military personnel records system to request documents.
Other individuals with a need for documents must still complete the Standard form 180, which can be downloaded from the online web site. Because the requester will be asked to supply all information essential for NPRC to process the request, delays that normally occur when NPRC has to ask veterans for additional information will be minimized. The new web-based application was designed to provide better service on these requests by eliminating the records centers mailroom and processing time.
Please pass this information on to former military personnel you may know and their dependents.

subset: commoncrawl


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"I used this card to showcase some of my own photography. All the information on the card is easy to read and the black and white photos make a subtle statement. Perfect."
"I am an artist and was looking for a design to showcase a painting or two on my business card. This was a perfect fit. I love that you can also print on the backside of the card. My only complaint would be that the recommended 8 pt type is too small for anyone over 40 to read without glasses!"
Copyright © 2004-2017 Shutterfly, Inc | Tiny Prints | Terms of Use. Designated trademarks and brands are the property of their respective owners.


text:
Version 1.10.0 of the Firebug web development tool has been released.
Information on new features can be found on this
page; they include a new cookie manager, command editor syntax
highlighting, autocompletion, CSS style tracing, and more. "Firebug
doesn't slow down Firefox start-up time anymore! It's loaded as soon as the
user actually needs it for the first time. Only the Firebug start-button
and menu is loaded at the start up time."


text:
5 Quick Reasons Why Your Startup Failed
Being a first time entrepreneur is fun and exciting, but nothing prepares you for the day you finally realized that things aren't working out. My partner and I ran a tech business for about two year...Read More
Fail Fast: 5 Weeks and $52 Dollars Later
A lot is said on how to plan a huge launch for your startup, then get a lot of people to see it and after this figure out if you are providing something that is valuable. I have unsuccessfully tried...Read More


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"Toddlers to Pre-Teens" is the 2nd of 4 talks in the series, "Turning the Titanic: Chastity Formation from Toddlers to Teens," presented by Katrina...
Dr. Bob Schuchts is a licensed marriage and family therapist who begins his talk, "Healing Broken Relationships" by discussing the various relationships, good and bad, that we all experience in our lives. Relationships define us, and we all need healing from the broken relationships that have left us wounded.
Is sanctity just for priests & nuns? Christopher West shows how the common vocation of marriage provides all of the necessary means to answer the universal call to holiness. A beautiful & inspiring talk! (1 DVD/2 CD set)
What is really essential for being a good husband or wife; a holy spouse? Christopher West contrasts ideas from the past with the down to earth theology of John Paul II in addressing this vital question.


text:
NIOS Class 10th English Question Paper 2013, NIOS Secondary Class 10th (X) 2013 English Question Paper NIOS Class X English Question Paper 2013 Secondary Students Free Download NIOS 10th – X English Model Question Paper for Students with Answers and Solution 2013 NIOS Board Exam Papers for Class 10 (X) std NIOS 2013 Sample English Question Bank with Full Details
Maximum Marks – 100
Time – 3 Hours
1. One of the ________ that I bought yesterday is broken. (cup/cups)
2. I need a pair of _________. (scissors/scissor)
3. Leena broke her ________. (spectacle/spectacles)
4. The _______ should help the poor (rich/riches)
5. It is wrong to sit _________. (idle/ideal)
6. I visited the trade ______. (fair/fare)
Click Here for more NIOS 10th Question Paper
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NIOS 10th English Question Paper 2013 Free Download For Secondary NIOS 2013 Exam Sample Model Paper
Want to know splr paper of eng 10 nios
Want to know splr paper of eng 10 nios


text:
Don't Forget To Vote In Today's Local Election
Make sure you get out and vote today! Every vote counts, besides local elections are just as important, if not more important, because they affect us immediately and directly. Find out what's on the ballot here.
Calcasieu Parish voters have a few tax propositions, judges, city councilmen and mayors to vote out or in today. Of course your precinct and district will determine what's on your ballot today. On a broad scope, here's what's at stake in today's April 5th election in Calcasieu Parish. Polls will be open from 8:30 A.M. – 6:00 P.M.
There are four tax propositions for voters to make decisions on and they include:
1.) A ¼ cent sales tax to expand sewage lines in unincorporated areas. Parish Administrator, Bryan Beam explained, "A lot of the sewage from individuals systems around the parish and residential areas especially goes into our rivers where people love to have recreation activity." Beam added, "We've had requests from hotels to be near the airport, but they require sewage."
2.) Maintenance tax renewal affecting Waterworks District Five of Wards Three and Eight. Director of Public Works, Allen Wainwright said, "It represents about 25% of the overall revenue in budget and so it's very significant to be able to take care of the assets the district owns and provide good clean water for those citizens."
3.) Mosquito control tax is up for renewal for the entire parish.
4.) Finally, a criminal justice tax renewal.
Other items that may show-up on your ballot are:
District Judge 14th Judicial District Court, ES 1, Div. F
Mayor City of Sulphur
Councilman Districts 1-4, City of Sulphur
Remember to have your photo I.D. and voter registration card to speed up the process or call 721.4000 if you have any questions. For voting precincts, times and places or to find out what's on your precinct ballot click here. For details call the Registrar of Voters office at 337-721-4000.


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[color=olive][/color]I'm making a pair of slippers that have an argyle pattern on the top. I found them in a book called Weekend Knitting. It says not to carry the yarn behind the work, and instead to cut it.
two questions:how do i make sure it stays together?how do i keep my brain sane when looking at each row of dangling strings?
and a third: where are all these strings going to go!? i know they belong woven into the fabric when it's done, but i have no idea how they're all going to fit.[/u]
happyskrappy,I don't have the book so I'll have to guess here.I'm thinking they are suggesting you work in intarsia. If the piece is worked in the round you won't be able to do an intarsia pattern in the normal method, instead, you would need to cut the yarn each time.
If you are not to work the piece in the round, I would suggest you wind some bobbins and not cut the yarn each row. There are lots of resources for basic intarsia. Almost any intro book for knit will cover it on some level.
As for your two questions, they are really one in the same, you would secure the yarn and ensure a hole-free fabric by weaving in your ends properly. I recommend you read this article from knitty:http://knitty.com/ISSUEfall04/FEATfall04tt.html
Use this technique to work your threads cleanly into fabric and make sure you do so in such a manner that you secure one color section to another.
I hope this helps.
Marnie, that's a great link, with great illustrations. I'll put it up on the site, at least until I can get around to making a video on weaving in ends!
Happyskrappy,I haven't done argyle socks before! But one of these days I'll do it, and when I do, of course I'll probably turn it into a video! LOL
I'm sure there are all sorts of tricks to doing argyle, and different ways. As Marnie said, you can cut each color change on every row, and work in the ends (lots of ends!).
But I'm wondering if it would be plausible to use this trick I just read about, for doing intarsia in the round....(Without cutting the yarn!) This trick will give you a seam up the back, and is sort of a combination of knitting flat and knitting in the round:
The idea is, you knit your way through one round, and then purl your way back (unusual for circular knitting!). You choose the point where you will be turning the work, probably at the back of the sock, and in a place where a seam stitch will be least noticed. You will increase an extra stitch here before you begin the first round of intarsia. This stitch will be the "seam", and will be slightly different looking than the other stitches. So, you create this seam stitch, and knit all the way around, doing intarsia, ending by knitting this seam stitch. Turn the work, and slip the seam stitch. Purl your way back around to the seam stitch and purl the seam stitch. Turn the work. Slip seam stitch, and work the round, ending by knitting seam stitch. Continue this way, always beginning a round by slipping the seam stitch, and ending the round by knitting or purling it.
This, of course, is total cheating for argyle! But why not?!
I haven't tried it, but it seems (seams!) like it would work! LOL
Another cheat would be just to work the piece flat, and then sew up the seam, and work with circular needles after the argyle pattern.
Now you've got me interested in trying argyle! I don't think I'd have the patience to do it any other way than a cheating way!


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Isner is 'putting it all together' in Cincinnati
by JAMES HENRY
CINCINNATI – Top-ranked American John Isner is basking in success on home soil again. But he's not done yet.
"I'm just very happy. Playing tournaments of this magnitude and being able to get wins like that on a packed stadium court full of American fans cheering me on, it's an unbelievable feeling," he said. "It's one that I haven't had too much at a tournament this level."
Isner defeated Juan Martín del Potro 6-7 (5), 7-6 (9), 6-3 to advance to the end of the Western & Southern Open in Cincinnati.
It was his third consecutive win against a top-10 player. He beat Milos Raonic, the newest and youngest member of the ATP World Tour Top 10, in the third round and World No. 1 Novak Djokovic in the quarterfinals.
Isner, who is projected to climb back into the top-20 rankings next week, will battle resurgent World No. 3 Rafael Nadal in the final, which is scheduled to start at 12:30 p.m. Sunday. The Spaniard ousted Tomáš Berdych 7-5, 7-6 (4).
"I've never beaten Rafa," Isner noted of their three previous encounters.
But, he added, he is up for the challenge.
It will be his second Masters 1000 final. He was the runner-up to Roger Federer in Indian Wells last year.
"It's awesome to be at this level, be at this stage. Again, I should say these are the toughest tournaments in the world, given the player field," he said. "It's a smaller draw, and everyone's entered. It's not a Grand Slam. Those are a much bigger draw. But everyone in the main draw is in the top 50 in the world. To be able to get to this stage, you've got to beat a lot of good players, and you have to have a lot of things go your way, which I have this week. I've caught a few breaks here and there. I'll take it and see what I can do tomorrow."
"It was a great experience last year in Indian Wells. I'll try to go out tomorrow and play as best as I can and see what happens."
Isner noted his playing level has improved recently.
"This tournament is where I'm really starting to put it all together. No offense to the other guys I've beaten prior to this, but like you just said, I've beaten three top-10 guys in a row," he said. "For me to do that, I have been playing well really in pretty much all facets of my game. There's definitely some stuff I can always improve on, but I do think I'm playing well."
He conceded, though, that he needs to perform better in competitions in other countries.
"I'm just comfortable in the U.S. It's something I need to prove on. Really sort of saved my season the last four years every time the summer rolls around in the states," he said. "I'm probably always going to play my best tennis in the states, but I can always improve over in Europe. One thing is these are surfaces I'm comfortable on, but also the support that I have from the fans and whatnot, it helps a lot."
"What it all comes down to is me being comfortable. I think that's the main key."
Following their match, Isner praised his semifinal opponent as "one of the better guys on the tour."
"There's no doubt about that. You ask anyone, and they will say the same," he said. "That's just how he is. He's a very, very good guy. I have nothing but the most respect for him."
"You know, we are good friends in the locker room. We're always saying, 'Hi.' We're very, very cordial with each other – as I said, he's a class act and a very good guy."
"Just as, you know, I think guys at the top of our game right now are all very, very classy individuals."
Photos by James Henry for OnTheGoTennis


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Free personalized radio that
plays the music you love
Angie Stone
Stone, a native of Columbia, South Carolina, began singing gospel music at a young age at First Nazareth Baptist Church. Her father, a member of a local gospel quartet, would take his only child to see performances by gospel artists such as the Singing Angels and the Gospel Keynotes. During her youth, she wrote poetry, played sports, and, after high-school graduation, was offered college basketball scholarships. While working dead-end jobs, Stone began saving money to record her own demos at a local studio called PAW. She joined Gwendolyn Chisholm and Cheryl Cook in the rap trio the Sequence, who recorded hits for Joe and Sylvia Robinson's Sugar Hill label -- "Funk You Up," a remake of Parliament's hit "Tear the Roof Off the Sucker" called "Funky Sound (Tear the Roof Off)," and "I Don't Need Your Love." Soon after, Stone was working with futuristic rap group Mantronix and rocker Lenny Kravitz, and she later formed the classy R&B trio Vertical Hold, who first charted with the Criminal single "Summertime." Besides "Seems You're Much Too Busy," the group's self-titled A&M album spawned another charting single, "ASAP." The group split after its second album.
Stone subsequently signed to Arista as a solo artist and recorded 1999's Black Diamond, a Top Ten R&B album that was certified gold on the strength of the singles "No More Rain (In This Cloud)" and "Everyday" (one of several songs she has written either for or with D'Angelo). The album won her a pair of Soul Train Lady of Soul Awards. She shifted to J for 2001's Mahogany Soul, another gold seller. Released in 2004, Stone Love fared just as well commercially, yet she moved to the revitalized Stax label for her fourth studio album, 2007's The Art of Love & War. It topped the R&B/Hip-Hop Albums chart and featured two of her best singles, "Sometimes" and "Baby" -- the latter of which received a Grammy nomination for Best R&B Performance by a Duo or Group with Vocals.
Throughout the next several years, the singer's studio output remained consistent in terms of chart performance, despite a series of label changes. Unexpected, released on Stax in 2009, hit the Top 20 of the R&B chart. Saguaro Road issued Rich Girl, Stone's most stylistically diverse set, three years later, and it peaked slightly higher. For Dream, released in 2015, she joined the veteran-loaded Shanachie roster. The next year, the Goldenlane label issued Covered in Soul, for which Stone updated classics popularized by the Guess Who, the Five Stairsteps, and Carole King. Also an actor, she has appeared in several movies, including The Fighting Temptations, Pastor Brown, and Scary Movie 5, as well as the television programs Moesha, Girlfriends, and Lincoln Heights. ~ Ed Hogan & Andy Kellman
Selected Discography
Track List: Covered In Soul
Track List: Dream
Track List: Rich Girl
Track List: Unexpected
Track List: The Art Of Love And War
Track List: Dance Vault Remixes - Bottles & Cans
Track List: Dance Vault Mixes: I Wasn't Kidding
Track List: I Wasn't Kidding
Track List: Stone Hits: The Very Best Of Angie Stone
Track List: Stone Love
Track List: Dance Vault Mixes - I Wanna Thank Ya
Track List: Mahogany Soul
Track List: Black Diamond
Track List: Black Diamond (Deluxe)
Similar Artists
Black Brother...St r o n g Brother
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text:
Four thousand run from the bulls in Virginia event
By Gary Robertson
PETERSBURG, Virginia (Reuters) - About 4,000 people - dressed in everything from thongs to superhero costumes - dodged 1,000-pound bulls as they sprinted down a quarter-mile dirt track on Saturday in rural Virginia's version of the running of the bulls in Pamplona, Spain.
It was the first event of what promoters say will be a nationwide, 10-city bull-running tour modeled on the annual Pamplona event.
"I just didn't want to die, to get trampled by bulls and die," said Cat Jones, 22, who works in engineering and traveled from New York City for the run.
"It was a rush ... a shot of adrenalin," she said.
Jones had such a thrill dodging bulls and watching them race by at break-neck speed that she paid $30 to run again in the afternoon.
The first six runs were conducted with about 500 runners each, chased by 12 bulls, and the last run featured 24 bulls chasing about 700 runners.
About 8,000 people came to watch the runs, said Rob Dickens, co-founder and chief operating officer of the Boston-based Great Bull Run. Most of those who signed up were 18 to 40 years old, and about 40 percent were women.
At least one runner suffered an injury that required a trip to a hospital. Another went to see a medic after being knocked down and stepped on by other runners. Continued...


text:
The Sixties designer of the 330-foot-tall Portland House in Victoria had a heart of concrete, judging by the grim-grey look of the place.
The architect chosen by Land Securities to convert the former cement-company headquarters into 206 flats is Sir David Chipperfield — and a look at the plans drawn up by the designer of the Turner Museum in Margate should bring a sunny glow to the hearts of locals, now being shown a leaflet of the plans.
The tower will be stripped to it concrete core. Two offset curved blocks clad in "high-quality masonry" will cup what is left. Owners will be able to stand on glass-fronted balconies supported by fluted Grecian columns.
There are 15 crash-pad studios and 43 one-bedroom flats. But the tower will be mostly filled with 75 two-bedroom and 73 three-bedroom flats. Don't all rush at once. Work does not start till 2015.
- More about:
- Architects
- Architecture
- Bedroom
- Bricklayer
- Greece
- Margate


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After last month's propaganda coup with its bomb attack on Hammersmith bridge in west London, the dissident republicans planted a small device on the Belfast-Dublin railway at Newry three weeks ago. It was its sixth attack in Northern Ireland this year, and was followed by a car bomb in Stewartstown, Co Tyrone.
There have been no injuries in any of its operations this year. But the railway bomb was a wake-up call to the security forces.
The small device was designed to entice them to the scene. Waiting for them was a bomb containing 250lb of homemade explosive, the plan being to kill as many RUC and army personnel as possible.
It was a favoured tactic of the Real IRA's former comrades in the Provisional IRA, from whom they split in autumn 1997. The dissidents were opposed to Sinn Fein signing up to the former US senator George Mitchell's principles of peace and democracy, the cornerstones on which the Good Friday agreement was to be built.
The Real IRA's subsequent campaign culminated in the Omagh car bombing of August 1998, the largest single atrocity of the Troubles. Although it is unlikely that the terror group intended murder, so reckless and amateurish was the operation that 29 died.
It called a ceasefire soon afterwards, and laid low. But a year later, the group's leader, a 50-year-old businessman from Dundalk, Co Louth, formerly an IRA quartermaster, restarted operations.
Its plans for a campaign in Britain initially stuttered. Attempts to smuggle homemade explosives and a car bomb from Irish ports in January and April 1998 were foiled as Gardai penetrated the outfit, and an incendiary bomb campaign that summer was also prevented.
But security sources feared in the aftermath of the Hammersmith bridge bombing that an active service unit had been established in England. Yesterday's operation appears to support fears that such a unit could strike again.
The loose alliance of dissident republicans, including Continuity IRA, more a flag of convenience these days for Real IRA activity, is thought to number about 120. As few as 30 are active terrorists.
The IRA's initiative on putting its arms beyond use, its offer to break the decommissioning crisis, boosted Real IRA support, although security forces are unable to quantify it. But a recent recruit was an IRA engineer with particular expertise in manufacturing mortars.
He joins a Dublin-based motorcycle courier who is the Real IRA's chief bomb-maker. He made the timing devices used at Omagh, and forensic scientists detected his hand in the Hammersmith device.
Its recent activities are an attempt to entice IRA members dubious about the decommissioning initiative and the policing bill. It is also raising two fingers at mainstream republicans, selecting Hammersmith bridge, which the IRA twice attacked unsuccessfully, and targets in the south Armagh area.


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Earlier today we told you that some retailers have been selling the tablet on Friday even though the launch date is actually July 30th. Which brings us to one of our loyal readers who managed to purchase one of the new Nexus 7 tablets from a GameStop today. After taking home the tablet and using it for 10 minutes, look at what happened to the Nexus name on the back of the tablet. As you probably know, ASUS is the company behind the Google Nexus 7, both the OG and the new versions of the slate.
Has anyone else had any sort of problem with the build quality of their new Nexus 7? Let us know by dropping a comment in the box below.
Thanks, Anonymous Tipster!


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Hello all! I'm so excited to announce Hell & High Water (THIRDS, Book 1) has placed 4th for Best Gay Paranormal Romance in the 2014 Rainbow Awards! How amazing is that? There were 520 books entered and nearly 170 judges in this fantastic event. So many wonderful books and authors. I'm honored to have made runner up. Thank you to everyone involved and congrats to my fellow authors and artists who won and placed in the awards.
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By Zelie Pollon
Issue 144 – September/October 2007
Later, when Monroe was a student at the University of Massachusetts, she'd stop black women on campus to ask if they were from Africa, and if so, if they were midwives. She was on a mission: to connect with the African midwifery tradition, and to imbue her own midwifery journey with its wisdom.
In 1982, the first of Monroe's seven children was born, with a Jewish midwife in attendance—at that time, there were no black midwives in Boston. It was obvious to Monroe there was a need to be filled, and she decided to create a network for black women. The result, the International Center for Traditional Childbearing (ICTC), was incorporated in 1991, in Portland, Oregon. Since then, the organization has become not only a training center for women in the Portland area, but an information clearinghouse for black women around the country who want to find support and kindred spirits in their areas. ICTC has since branched out across the country and to Africa and South America. And in 2002, the ICTC sponsored the first annual Black Midwives and Healers Conference. Monroe's dream of community—one that includes men and women—was beginning to emerge. "This is not a feminist movement, it's a family movement," she says—white families as well as black.
Part of Monroe's mission is to teach African Americans their history. She wants midwives of all cultures to remember the important position they once held in community health care—a place she feels they should hold again. It was midwives who kept communities together, serving every aspect of health and every member of a family. For Monroe, being a midwife—particularly for the African-American community—means playing a key role in educating black women about their health, reducing infant mortality, and showing women how to raise healthy children with tenderness and attention. These are goals to which Monroe—she won't give her age, but seems to have more dynamism and energy than most teenagers—has dedicated her life. She hopes that, through ICTC, other African-American midwives will carry on the tradition after she's gone.
ICTC is one of the few organizations in the country dedicated to educating and training black midwives. Any doubt about the need for such training is quickly dissipated by a glance at the statistics: Overall, the US has one of the highest rates of infant mortality in the developed world, and the rate for African Americans is almost twice that: 13.6 deaths per 1,000 live births, according to a National Vital Statistics Report.2 The reasons for this are intrinsic to the system we live in, says Monroe, who adds that training and supporting midwives is part of the answer.
"We have a legacy, and we should have ownership of this," Monroe says of black midwives. "We need to build up the infrastructure in this society and deal directly with the issues that affect us, including higher levels of poverty, lack of access to quality health care, and higher levels of stress." According to Monroe, the women who enter the ICTC want to be empowered to have the best birth experiences possible, but are subject to health care and societal systems that discriminate against them.
So Monroe sees her job—and the job of any midwife—as also one of making alliances within the black community in the areas of family, work, and education. She makes home visits during which she spends time with each member of the family just celebrating the baby. She makes sure everyone is adjusting well, and may assist with breastfeeding, or show a new dad how to bathe the baby.
ICTC works hard to teach black families about the benefits of doulas, also referred to as sisterfriends and birth companions. In some cases, Monroe invites her clients to attend doula trainings, where they can learn about the labor, postpartum, and breastfeeding support services doulas provide. Last year in Oregon, Monroe helped 200 people, graduated 25 doulas, gave free doula services to 65 low-income women, and taught hundreds of hours of infant-mortality prevention classes.
To Monroe, building a community begins at ground level. ICTC's Sistah Care program gives teenage girls interested in midwifery and women's health care an opportunity to train in these areas for one year. The program includes learning childbirth skills, cultural awareness, and the history of midwifery practice. There's a three-and-a-half-day training workshop for doulas, and a two-year online midwife-training program is being developed.
The ICTC's Black Midwives and Healers Conference is one of the biggest builders of community. Practitioners from around the world gather at this annual event to discuss health, community, and midwifery practice. The fifth conference was held in the fall of 2006 in Phoenix, Arizona, and offered workshops on everything from doulas to dads. But the most important part of the conference is creating a network.
Cultural awareness and historical awareness are parts of every ICTC program, and figure prominently in Monroe's speaking engagements, weekly meetings, and annual conferences. Slavery affected generations of black families' childrearing practices. "If we yell at our children, 'I'm going to whip you with a switch!,' well, that's from enslavement. We've copied the language of our oppressor," Monroe asserts. ICTC teaches African-centered childrearing practices including extended breastfeeding, babywearing, positive physical contact and affection, and nonviolent discipline methods.
Karen McFee, now a 23-year-old nursing student, is a graduate of Sistah Care. She recalls that it was through the program and Monroe's mentorship that she found her inspiration and her calling. "Seeing someone who is my race doing this encourages me to keep going, and shows me that I can do it too." Through the training, McFee learned details that she never knew, such as the basics of nutrition, particularly for African Americans. Dairy foods, for example, aren't good for the large numbers of black people who are lactose-intolerant. In Africa they had goats, not cows, McFee learned, so many black people do better with goat milk. She learned about other technical aspects—of delivery, drugs, and health—but the more important lessons were about caring for one another and for the community.
Ruth Kaufman, a white woman who runs a small midwifery practice in Albuquerque, New Mexico, joined ICTC last year. She sees the ICTC training—which incorporates all of a community's health issues—as an answer to failing US health systems and the poor health statistics of minorities. Kaufman's work now is to meld ICTC's midwife-training program with larger health issues in New Mexico, such as teen pregnancy and sexual assault.
Kaufman feels that, just as people should be seeking out midwives, midwives should be seeking out new models of caring for their communities. "Shafia is a model for that," she says. As traditional practices in other countries continue to be abandoned, and replaced with what people think are "more advanced" Western methods, Monroe's work is not likely to get any easier. "Now, in some [African] countries, they're doing things we did in the 1950s: holding the baby up [at birth], slapping it on the butt." Countering such cultural shifts requires a lot of awareness and cultural sensitivity—and money. ICTC's budget—mostly from grants, and membership and conference fees—covers only about a third of what Monroe feels the center needs to fully fund its necessary work.
In the coming year, the organization's efforts to get people involved will extend to Internet classes. The ICTC won't hold the Black Midwives and Healers Conference this year, and will focus instead on expanding the number of ICTC chapters and representatives. ICTC will also be cosponsoring this year's Midwives of North America Conference. Monroe believes it's time for midwives, particularly African-American midwives, to own their own legacy and stop being isolated and marginalized. "We want to give women pride. Now black women say, 'Thank you for providing a place for us to learn about our culture and the contributions we have made to midwifery.'"
For the notes to this article, see www.mothering.com/articles…legacy-black-midwives-notes.html.
International Center for Traditional Childbearing (ICTC): 2823 N. Portland Blvd., Portland, OR 97217; 503.460.9324; [email protected]; www.blackmidwives.org. Sistah Midwife International: PO Box 11303, Portland, OR 97211; 503.281.1688; [email protected]; www.sistahmidwife.com. Purchase Shafia M. Monroe's Black Midwives and Prenatal Providers Directory: Essential Recipes and Words of Wisdom for Expecting and New Parents from Sistah Midwife International.
Zelie Pollon is a freelance writer based in Santa Fe, New Mexico.


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An academic who apparently received his doctorate in a short time when regulations stipulate normal studies should be three to six years, is at the centre of a storm of controversy after being appointed to a scandal-hit Welsh business school, The Eye can reveal.
Major questions are also now being raised by senior staff at Swansea university about whether due process was followed in the appointment of Professor Steve Chan to the institution's School of Management, which hit the headlines when the then Dean resigned suddenly following a series of scandals exposed by us.
A source within the university told The Eye: "This whole thing is highly suspicious".
Another said: "Apparently, he (Professor Chan) is Director of 'Swansea University's Network/Relationship Science Analytics Programme' which almost no-one has heard of here at Swansea."
Professor Chan was awarded his 'untitled' doctorate in 2013, when university rules dictate that normally the minimum 'candidature' for a full-time Ph.D student is three years, and six years if studies are taken part-time.
He lists a series of posts elsewhere, indicating he was not a full-time student, so must have been available for a minimum of 35 hours per week, suggesting he was studying for at least two years at Swansea university.
The only alternative is if a doctorate candidate had been a Ph.D student at another high-quality institution such as Harvard or Massachusetts Institute of Technology (MIT) and transferred to Swansea, following a recommendation from the relevant head of school, so that the period of study at the institution is recognised.
At Swansea Professor Chan is "Professor of Smarter Cities for a Safer Planet and the Internet of Things as well as Chair of Cyber Analytics and Network/Relationship Science".
His Ph.D was supervised by the Dean of the School of Management, Marc Clement, his present boss, who has retained his role at the university's medical school, and he was also a 'Fellow' at a controversial scholarship project run by Professor Clement, where serious irregularities were identified by auditors.
His work was also supervised by Mark Rees, another academic at the medical school.
One of the Swansea university sources told The Eye: "Given his (Professor Chan's) alleged area of expertise in big data science, which one can assume his Ph.D was researching, why then are two medical professors supervising this student?
"You would expect professors from the university's renowned 'Department of Computer Science' to be doing this.
"Such supervisory practices would not normally be allowed by any academic institution as it would be expected that supervisors are experts in the field being studied by their doctoral students.
"In terms of the academic credibility of Swansea university, the real question is how someone who has just been awarded a Ph.D can become a chair almost immediately at our institution."
The university is at the centre of inquiries about Professor Chan, who also has connections with Hawaii university.
His official CV says: "At Hawaii Pacific University, (I am) a Research Professor of Sensemaking and Visualization Analytics."
Swansea say Professor Chan "is the Director of Swansea University's Network/Relationship Science Analytics PhD Programme, focusing upon those Sensemaking methodologies and tools that will facilitate moving from Big Data to Big Insights to effectuate more robust decision-making when approaching the Big Problems that necessitate Big Decisions – the realm of Context Computing,"
The Eye have asked what this means.
A series of questions is also being posed by staff at the university.
One of the internal sources told The Eye: "Did Steve Chan do the minimum time of study required by the Ph.D regulations?
"Who were the 'external examiners'?"
But his superior, Professor Clement, is no stranger to controversy either.
When he was named as the new Dean of the management school in the summer, senior academics warned that his appointment may be "a disaster waiting to happen".
At the university's college of medicine he supervised the work of a large number of students, and was in charge of the University of Wales before it virtually collapsed.
Commentators said at the time they believed the school needed a full-time official in charge, after being engulfed in scandal over the former Dean, Nigel Piercy.
Sources within Swansea university told The Eye Professor Clement was the wrong official for the job.
Professor Piercy resigned suddenly as Dean in July, after calling his critics "grubby little people".
His son Niall, also quit the school two weeks after his father, but his wife, Nikala Lane, remains.
One source told The Eye at the time: "It is worth noting that whilst he (Marc Clement) was Vice Chancellor of the University of Wales, he was supervising ELEVEN Ph.Ds at Swansea University (all awarded in 2010).
"Who allowed him to do this?
"No wonder he didn't have time to focus on ensuring the University of Wales survived.
"He is now going to be doing the same at the School of Management whilst … supervising far too many research students.
"What will happen to academic standards within the School of Management?
"It is another disaster waiting to happen and would never happen in other universities."
The Eye have revealed further controversies about the past of Professor Clement.
He was a key figure in a scholarship project at the centre of a scandal over funding, where Professor Chan has connections.
Under the £11.4 million Prince of Wales Innovation Scholarship (POWIS) high-flying graduates from all over the world were meant to be singled out for Ph.D projects that would see them embedded in new hi-tech companies creating employment opportunities.
Each student was to receive a stipend of £20,000 a year, as well as a research grant of £5,000 and get all tuition fees paid.
Prince Charles said when it was launched: "It seeks to take the best of Wales to the world and bring the best of the world to Wales.
"The scholarships are, I think, a very practical and very exciting response to how higher education can help the Welsh economy in a time of crisis."
But in 2011 the Cardiff bay Government's Welsh European Funding Office (WEFO) withdrew financial backing from POWIS, which was run by the University of Wales where Professor Clement was Vice Chancellor, after serious irregularities were identified by auditors.
In their report three men, including Professor Clement, were identified as having overlapping interests in seven companies.
It was also revealed that one of the first beneficiaries of POWIS was the daughter of Professor Richard Davies, Vice Chancellor of Swansea University, his overall boss.
Yet she did not hold a first-class degree as the scheme stipulated.
As well as POWIS, Professor Clement was also closely linked to the ill-fated Technium initiative, which was designed to foster new companies.
Some Techniums have had extremely poor occupancy rates and six were scrapped five and a half years ago.
He was also the senior official in charge at the University of Wales, when a huge row erupted over the validation of bogus degrees.
In November 2010, BBC Wales screened an episode of their TV current affairs series Week In Week Out which claimed that Fazley Yaakob, a pop star and head of Fazley International College, a University of Wales partner in Malaysia, held bogus degrees.
Following a second BBC investigation, the vice-chancellors of Cardiff, Swansea, Aberystwyth, Bangor and Glamorgan universities – known collectively as the St David's Day Group – called for an end to the University of Wales.
Yet Professor Clement controversially exercised an 'option to return' to Swansea as the University of Wales effectively abolished itself following a 'merger' with Trinity St David's.
Six days ago The Eye submitted a series of questions about Professor Chan and his appointment to Swansea university.
There has been no answer.
Perhaps they need lessons from their 'professor of sensemaking'.
Tomorrow – huge questions about ranking system hailed by Swansea university officials for placing them at 161, but which puts little known institutions at the top.


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Just in case if you didn't know, I'm a 16-year-old boy. This is a romantic comedy/drama about an old couple's marriage. That's not exactly the type of movie that I want to see. By the look of the trailers, the movie looks like it could be a good time and the movie got really good reviews to boot. And surprisingly, I really did enjoy Hope Springs. It's nothing great, it's nothing that you should run out and see, but it's a really good movie.
Hope Springs is about a married couple which consists of Kay (Meryl Streep) and Arnold (Tommy Lee Jones). Their marriage isn't going too well. They hardly talk to each other, they barely kiss, and they don't even sleep in the same room. Kay wants to spice things up but Arnold isn't getting the message. She signs her and Arnold up to go to a couple's specialist (Steve Carell) in order to save their marriage.
So, that's not exactly the movie that a 16-year-old boy would see but I actually did like the story in Hope Springs. To the best of my knowledge we haven't had a movie about marriage problems recently and Hope Springs is an original movie. I will always give props to that. The story is entertaining and is well told with much of that having to do with the characters.
Kay and Arnold seem like real people. Sometimes in these types of movies you have strange and weird people so nobody can relate to them. While I personally don't relate to Kay and Arnold for obvious reasons, they came off as realistic which is always a plus. Meryl Streep and Tommy Lee Jones are excellent actors and they both give good performances here. Steve Carell as the marriage counselor was also good as he came off as a real person too.
As a comedy, this movie didn't really make me laugh. Again, I'm 16-years-old so maybe that's why but I didn't see too many moments where it would be funny. I would honestly say this movie is more of a drama. I felt for both of the characters, the subject matter really isn't that funny, and the characters aren't exactly happy. The only funny thing this movie could have going for it is the awkwardness of the whole thing. Other than that, it's not really a comedy which is what the trailers made it seem.
There's really not much to say about Hope Springs. I enjoyed the movie and I liked the characters and performances. I was expecting a comedy but got more of a drama. That's certainly not a bad thing but it was kind of strange. If you were interested in Hope Springs then you will like the movie. If you didn't care about it then it's nothing too special and not worth your time. But then again I didn't really care for it and I enjoyed it so keep that in mind.


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Fri, May 12, 2017, 7:00 pm - 9:00 pm
Cape Cod Theatre Company
105 Division St. West Harwich, MA, 02671
Longitude X Latitude: -70.12133840000001, 41.6676972
Cape Cod Arts, Cape Cod Events, Cape Cod Theatre, Cape Cod Theatre Company, Musicals, Plays, West Harwich
Wrinkles, The Musical opens on Thursday, May 11, 2017, at the Cape Cod Theatre Company in West Harwich. The play will run through June 11, 2017. Shows start at 7:00 pm on Thursdays, at 7:30 on Friday and Saturday evenings and the Sunday Matinee starts at 4:00 pm. There will be no show on Thursday, May 25.
The Cape Cod Theatre Company presents the premiere of Wrinkles, the Musical, A Celebration of Women and Aging written by Naomi Turner and Wilderness Sarchild; directed by Nina Schuessler; with music by Grammy Award winner Jason Howland, Cape recording artist Sarah Burrill, and composer and musical director Malcolm Granger.
In 2008, two dear friends celebrated their 60th birthdays. One went on a silent retreat for three weeks and wrote poetry. The other got a personal trainer, cosmetic dentistry, Botox, Juvaderm, and laser treatments. Using one of the poems, Hags and Crones as their inspiration, the two created the Wrinkles Review. The work was further shaped, developed, and directed by Broadway producer and longtime friend, Dani Davis as a "work in progress" performance at WHAT in 2010.
Sold out houses and standing ovations encouraged the writers to keep working toward the development of an evening-length, two-act musical. With the intention of empowering older women, the writers based the script on real stories of Cape women ages 60-95 shared in workshops, interviews, and seminars.
The piece is written for a mature audience.
For more information or tickets, see the company site.
We try to be as accurate as possible with our listings. We recommend that you check the event's website, organizer or the event venue before you plan your trip. Sometimes the dates or the times are incorrect and at other times, the event might be canceled because of bad weather or other circumstances. Please let us know if you find a mistake in our Massachusetts events listings. Contact us and let us know how we're doing.
MORE Southeast Massachusetts Events
Master Artist ExhibitThe Cape Cod Art Association presents its Fourth Annual Master Artist Exhibit, an exhibition honoring the creative talent of their Master Artist Members. The show runs from Monday, June 5 to Sunday, July 9, 2017. The reception for the exhibition is on Thursday, June 8, from 5:00 to 7:00 pm. The CCAA's Master Artists have [...]
Yarmouth Summer KickoffYarmouth welcomes summer with a kickoff celebration that runs for five days. The celebration features a sand castle building contest, nature walks, yoga, baseball, a painting class, a farmers market, free movies on the beach, ballroom dancing, a fishing derby, an ice cream social, a dog parade, a blessing of the boats, and more. The [...]
Middleborough CarnivalMiddleborough celebrates the Fourth of July with a five-day carnival and fireworks. The carnival runs from Friday, June 30 to Tuesday, July 4, 2017. The events and special offers for the carnival vary almost every day. On Tuesday, July 4th, the fair opens early. Daytime wristbands are available from 1 to 5:00 pm and Nighttime [...]
Braintree 4th of JulyBraintree celebrates the fourth early on Saturday, July 1, 2017. The community has scheduled an entire day chocked full of events for the entire family at Braintree High School. The celebration includes a parade, games and carnival rides, local food vendors, a salute to veterans, raffle drawings, and an extensive list of performers that start [...]
Halifax Family Fun DayHalifax will celebrate the Fourth of July with a full day of activities on Saturday, July 1, 2017. There is a Family Fun Day on the town green at noon and fireworks at the school in the evening. The family event features bounce houses, a DJ, balloon animals, face painting, local food vendors, games, and [...]
Hingham FireworksHingham celebrates the Fourth of July with two days of celebrations. The fireworks are part of a community event hosted by the local Lion's Club. The event begins at 3:00 pm at the Hingham Harbor Gazebo. Children's and family activities include patriotic face painting, a bounce house, balloons and more. At 5:00 pm the pre-concert [...]
Halifax FireworksHalifax will celebrate the Fourth of July with a fireworks display on Saturday, July 1, 2017. The evening's festivities begin at Halifax Elementary School at 6:00 pm. There will be local food vendors and a balloon animal artist before the show starts. The fireworks are scheduled to begin at dusk, or about 9:15 pm. Earlier [...]
Braintree FireworksBraintree celebrates the fourth early on Saturday, July 1, 2017. The community has scheduled an entire day chocked full of events for the entire family. Events include a parade, games and carnival rides, a Food Truck Festival, a salute to veterans, raffle drawings, and a long list of performers that start about 3:00 pm and [...]
Brewster Historical Society Farmers MarketThe Brewster Historical Society Farmers Market is a new seasonal Farmer's Market for 2017. The market is open from June 25 to September 24. The hours are every Sunday morning from 9:00 am to 1:00 pm PM at Windmill Village. adjacent to Drummerboy Park). The market features fresh local produce, seafood, organic meats, plants, and [...]
Orleans FireworksOrleans celebrates the 4th of July with a fireworks display on Sunday, July 1, 2017, and a patriotic parade on Tuesday, July 4, 2017. The fireworks program begins at 8:30 pm and runs till 9:30 pm. The show should start around dusk. You can view the show from the waterfront near Rock Harbor on Bay [...]


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Long-term impact of alcohol on the brain
While researchers have found that moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence,[1] excessive alcohol consumption is associated with widespread and significant brain lesions. The effects can manifest much later—mid-life Alcohol Use Disorder has been found to correlate with increased risk of severe cognitive and memory deficits in later life.[2][3] Alcohol related brain damage is not only due to the direct toxic effects of alcohol; alcohol withdrawal, nutritional deficiency, electrolyte disturbances, and liver damage are also believed to contribute to alcohol-related brain damage.[4]
Adolescent brain development[edit]
Consuming large amounts of alcohol over a period of time can impair normal brain development in humans.[5] Deficits in retrieval of verbal and nonverbal information and in visuospatial functioning were evident in youths with histories of heavy drinking during early and middle adolescence.[6][7]
During adolescence critical stages of neurodevelopment occur, including remodeling and functional changes in synaptic plasticity and neuronal connectivity in different brain regions. These changes may make adolescents especially susceptible to the harmful effects of alcohol. Compared to adults, adolescents exposed to alcohol are more likely to exhibit cognitive deficits (including learning and memory dysfunction). Some of these cognitive effects, such as learning impairments, may persist into adulthood.[8]
Mechanisms of action[edit]
Ethanol can trigger the activation of astroglial cells which can produce a proinflammatory response in the brain. Ethanol interacts with the TLR4 and IL-1RI receptors on these cells to activate intracellular signal transduction pathways. Specifically, ethanol induces the phosphorylation of IL-1R-associated kinase (IRAK), ERK1/2, stress-activated protein kinase (SAPK)/JNK, and p38 mitogen-activated protein kinase (p38 MAPK). Activation of the IRAK/MAPK pathway leads to the stimulation of the transcription factors NF-kappaB and AP-1. These transcription factors cause the upregulation of inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2) expression.[9] The upregulation of these inflammatory mediators by ethanol is also associated with an increase in caspase 3 activity and a corresponding increase in cell apoptosis.[9][10] The exact mechanism by which various concentrations of ethanol either activates or inhibits TLR4/IL-1RI signaling is not currently known, though it may involve alterations in lipid raft clustering [11] or cell adhesion complexes and actin cytoskeleton organization.[12]
Changes in dopaminergic and glutamatergic signaling pathways[edit]
Intermittent ethanol treatment causes a decrease in expression of the dopamine receptor type 2 (D2R) and a decrease in phosphorylation of 2B subunit of the NMDA receptor (NMDAR2B) in the prefrontal cortex, hippocampus, nucleus accumbens, and for only D2R the striatum. It also causes changes in the acetylation of histones H3 and H4 in the prefrontal cortex, nucleus accumbens, and striatum, suggesting chromatin remodeling changes which may mediate long-term alterations. Additionally, adolescent rats pre-exposed to ethanol have higher basal levels of dopamine in the nucleus accumbens, along with a prolonged dopamine response in this area in response to a challenge dose of ethanol. Together, these results suggest that alcohol exposure during adolescence can sensitize the mesolimbic and mesocortical dopamine pathways to cause changes in dopaminergic and glutamatergic signaling, which may affect the remodeling and functions of the adolescent brain.[13] These changes are significant as alcohol's effect on NMDARs could contribute to learning and memory dysfunction (see Effects of alcohol on memory).
Inhibition of hippocampal neurogenesis[edit]
Excessive alcohol intake (binge drinking) causes a decrease in hippocampal neurogenesis, via decreases in neural stem cell proliferation and newborn cell survival.[14][15] Alcohol decreases the number of cells in S-phase of the cell cycle, and may arrest cells in the G1 phase, thus inhibiting their proliferation.[14] Ethanol has different effects on different types of actively dividing hippocampal progenitors during their initial phases of neuronal development. Chronic alcohol exposure decreases the number of proliferating cells that are radial glia-like, preneuronal, and intermediate types, while not affecting early neuronal type cells; suggesting ethanol treatment alters the precursor cell pool. Furthermore, there is a greater decrease in differentiation and immature neurons than there is in proliferating progenitors, suggesting that the abnormal decrease in the percentage of actively dividing preneuronal progenitors results in a greater reduction in the maturation and survival of postmitotic cells.[15]
Additionally, alcohol exposure increased several markers of cell death. In these studies neural degeneration seems to be mediated by non-apoptotic pathways.[14][15] One of the proposed mechanisms for alcohol's neurotoxicity is the production of nitric oxide (NO), yet other studies have found alcohol-induced NO production to lead to apoptosis (see Neuroinflammation section).
- ^ Lang, I.; Wallace, R. B.; Huppert, F. A.; Melzer, D. (2007). "Moderate alcohol consumption in older adults is associated with better cognition and well-being than abstinence". Age and Ageing. 36 (3): 256–61. PMID 17353234. doi:10.1093/ageing/afm001.
- ^ Caroline Cassels (July 30, 2014). "Midlife Alcohol Abuse Linked to Severe Memory Impairment". Medscape. WebMD LLC.
- ^ Kuźma, E. B.; Llewellyn, D. J.; Langa, K. M.; Wallace, R. B.; Lang, I. A. (2014). "History of Alcohol Use Disorders and Risk of Severe Cognitive Impairment: A 19-Year Prospective Cohort Study". The American Journal of Geriatric Psychiatry. 22 (10): 1047–1054. doi:10.1016/j.jagp.2014.06.001.
- ^ Neiman, J. (Oct 1998). "Alcohol as a risk factor for brain damage: neurologic aspects". Alcohol Clin Exp Res. 22 (7 Suppl): 346S–351S. PMID 9799959. doi:10.1111/j.1530-0277.1998.tb04389.x.
- ^ Tapert SF, Brown GG, Kindermann SS, Cheung EH, Frank LR, Brown SA (February 2001). "fMRI measurement of brain dysfunction in alcohol-dependent young women". Alcohol. Clin. Exp. Res. 25 (2): 236–45. PMID 11236838. doi:10.1111/j.1530-0277.2001.tb02204.x.
- ^ Squeglia LM, Jacobus J, Tapert SF (January 2009). "The influence of substance use on adolescent brain development". Clin EEG Neurosci. 40 (1): 31–8. PMC 2827693 . PMID 19278130. doi:10.1177/155005940904000110.
- ^ Brown SA, Tapert SF, Granholm E, Delis DC (February 2000). "Neurocognitive functioning of adolescents: effects of protracted alcohol use". Alcohol Clin Exp Res. 24 (2): 164–71. PMID 10698367. doi:10.1111/j.1530-0277.2000.tb04586.x.
- ^ Guerri, C.; Pascual, M. A. (2010). "Mechanisms involved in the neurotoxic, cognitive, and neurobehavioral effects of alcohol consumption during adolescence". Alcohol. 44 (1): 15–26. PMID 20113871. doi:10.1016/j.alcohol.2009.10.003.
- ^ a b Blanco Am, V. S. S.; Vallés, S. L.; Pascual, M.; Guerri, C. (2005). "Involvement of TLR4/type I IL-1 receptor signaling in the induction of inflammatory mediators and cell death induced by ethanol in cultured astrocytes". Journal of immunology (Baltimore, Md. : 1950). 175 (10): 6893–6899. PMID 16272348. doi:10.4049/jimmunol.175.10.6893.
- ^ Pascual, M.; Blanco, A. M.; Cauli, O.; Miñarro, J.; Guerri, C. (2007). "Intermittent ethanol exposure induces inflammatory brain damage and causes long-term behavioural alterations in adolescent rats". European Journal of Neuroscience. 25 (2): 541–550. PMID 17284196. doi:10.1111/j.1460-9568.2006.05298.x.
- ^ Fernandez-Lizarbe, S.; Pascual, M.; Gascon, M. S.; Blanco, A.; Guerri, C. (2008). "Lipid rafts regulate ethanol-induced activation of TLR4 signaling in murine macrophages". Molecular Immunology. 45 (7): 2007–2016. PMID 18061674. doi:10.1016/j.molimm.2007.10.025.
- ^ Guasch, R. M.; Tomas, M.; Miñambres, R.; Valles, S.; Renau-Piqueras, J.; Guerri, C. (2003). "RhoA and lysophosphatidic acid are involved in the actin cytoskeleton reorganization of astrocytes exposed to ethanol". Journal of Neuroscience Research. 72 (4): 487–502. PMID 12704810. doi:10.1002/jnr.10594.
- ^ Pascual, M.; Boix, J.; Felipo, V.; Guerri, C. (2009). "Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat". Journal of Neurochemistry. 108 (4): 920–931. PMID 19077056. doi:10.1111/j.1471-4159.2008.05835.x.
- ^ a b c Morris, S. A.; Eaves, D. W.; Smith, A. R.; Nixon, K. (2009). "Alcohol inhibition of neurogenesis: A mechanism of hippocampal neurodegeneration in an adolescent alcohol abuse model". Hippocampus. 20 (5): 596–607. PMC 2861155 . PMID 19554644. doi:10.1002/hipo.20665.
- ^ a b c Taffe, M. A.; Kotzebue, R. W.; Crean, R. D.; Crawford, E. F.; Edwards, S.; Mandyam, C. D. (2010). "Long-lasting reduction in hippocampal neurogenesis by alcohol consumption in adolescent nonhuman primates". Proceedings of the National Academy of Sciences. 107 (24): 11104–11109. PMC 2890755 . PMID 20534463. doi:10.1073/pnas.0912810107.


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Archive of October 2004
MPs urge action on road deaths
MPs are pressing the Government to overhaul road safety laws and apply tougher sentences and higher fines to those who cause death or injury by dangerous driving.
£7 million ad campaign to cut crime
The Home Office has launched a £7 million advertising campaign in an attempt to cut robbery, burglary and car crime.
Labour tops poll despite Iraq effect
Only two in ten voters agree Britain's unflinching support for the Iraq war was "good" for Britain, according to new poll.
Galloway to work for release of British hostage
George Galloway MP has appeared on al-Jazeera TV to appeal for the immediate release of British hostage, Margaret Hassan.
Kinnock to make case for compulsory voting
European Commissioner Neil Kinnock has pledged to make the case for compulsory voting after he receives his life peerage in the House of Lords.
Jowell willing to consider changes on Gambling Bill
The Culture Secretary Tessa Jowell has today signaled that she is willing to consider amendments to the Gambling Bill as it progresses through its Parliamentary stages.
TUC warning over job cuts
Government plans to axe 71,000 civil service jobs will prove to be a 'false economy' and could obstruct public sector reforms, according to a TUC report published today.
EU treaty vote "in early 2006"
Britain may hold a referendum on the European Union's constitution "in early 2006", the Foreign Secretary said on Friday.
Kinnock and Patten receive life peerages
Two outgoing European Commissioners are to receive life peerages in the House of Lords.
Prescott denies plans to review council housing transfers
Deputy Prime Minister John Prescott has denied he agreed to review the Government's policy on council housing transfers, following widespread reports that a review was underway.
Lords' hunting compromise "not sufficient"
The Government's spokesman on rural affairs in the Lords, Lord Whitty, has said Peers have not gone far enough in seeking a compromise on hunting.
Heroin is biggest threat to Afghanistan, says Straw
Foreign Secretary Jack Straw said today that Afghanistan's opium production was the biggest threat to the war-torn country's attempts to rebuild itself - but added that he expected production of the drug to increase next year.
Blair signs EU treaty
Prime Minister, Tony Blair, has joined EU counterparts in Rome today in a ceremony to sign the historic European Union constitution.
Campaigners call for action not words on climate change
Environmental campaigners have called on the Government to take concrete action against climate change, rather than just launching strategies.
Campaigners urge "fourth way" in council house funding
MPs, trade union bosses and councillors are meeting today in London to discuss how best to push the Government to move to a "fourth way" in council house funding.
Londoners back Olympic Games
According to a new opinion poll from ICM, Londoners are fully behind the capital's bid for the Olympic Games in 2012.
Funding boost for Scotland's national parks
The Scottish Executive has announced a funding boost for Scotland's national parks.
Howard attacks EU Constitution
Conservative Party leader Michael Howard today warned that the EU Constitution would be "a giant ball and chain round the ankle of British business".
ASBOs reviewed
The Government will today release an analysis of how successful its crackdown on anti-social behaviour has been.
National RE framework launched
The Education Secretary has launched a new framework for Religious Education (RE) in England and Wales.
Sir Ian Blair appointed new Met chief
Sir Ian Blair has today been confirmed as the new Commissioner of the Metropolitan Police.
Home Office wins Bicester asylum centre case
The Home Office has won its appeal court case over the siting of an asylum seeker accommodation centre in Bicester, Oxfordshire.
Blunkett apologises for "premature" homicide review announcement
The Home Secretary David Blunkett has apologised to MPs for an announcement on the review of murder law which was released to the press before MPs.
Jamieson confident in Galileo's potential
The Transport Minister David Jamieson has expressed full confidence in the future of the EU's Galileo satellite positioning system.
Ottaway steps down from frontbench
The Conservative environmental spokesman has announced that he is stepping down from his frontbench position.


text:
Detroit art museum warns auction could be death knell
By Nick Brown and Joseph Lichterman
(Reuters) - A top officer at the Detroit Institute of Arts predicts near-certain closure for the museum if Detroit sells major pieces from the 60,000 works in the institute's art collection as a way to address the city's dire financial situation.
In an interview Wednesday, Annmarie Erickson, the DIA's chief operating officer, told Reuters the museum could lose significant funding if pieces from the collection are sold.
"It would certainly mean the closure of the museum, maybe not tomorrow, but eventually," Erickson said. "Our situation is in some respects just as dire as that of the creditors."
But with Detroit facing more than $18 billion in debt and retired city workers confronting cuts to pension and health benefits, the museum could have a tough time making a case for preserving its assets, bankruptcy experts say. Kevyn Orr, the state-appointed financial manager, has not ruled out the sale of DIA treasures to address the city's financial plight.
The rocky outlook for cultural assets like the DIA illustrates the tough choices facing a city once considered the cradle of American vehicle manufacturing. Like General Motors and Chrysler - Detroit titans that survived collapse by having painful decisions thrust upon them via bankruptcy - the city may have to part with cultural gems to bounce back from disaster.
Mark Young, president of the Detroit Lieutenants and Sergeants Association, which represents about 500 mid-level managers in Detroit's police department, said art should not outweigh workers, whose pensions and benefits are likely to face big cuts as Detroit restructures.
"The Van Gogh must go," said Young. "We don't need Monet - we need money."
The Detroit Institute of Art is not the only major cultural institution that could be caught up in Detroit's bankruptcy proceedings. Belle Isle, a 982-acre recreational spot in the Detroit River, as well as the Detroit Zoo could both be sold. Continued...


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Ignoring conservative record, MSNBC's Barnicle claimed that McCain is "in the middle"
Research ››› ››› MATT GERTZ
On Morning Joe, Mike Barnicle claimed that while in "most campaigns," "Republicans begin on the right for their campaign and come to the middle for the fall," John McCain is "in the middle and he has to swing right for the primaries." In fact, McCain has already shifted rightward on immigration and taxes, and McCain himself has asserted that he is a "mainstream conservative."
On the February 11 edition of MSNBC's Morning Joe, co-host Mika Brzezinski asked whether Republican presidential candidate John McCain would "potentially alienate himself from independents and other Republicans" by "trying to appeal to the conservative base." In response, guest co-host Mike Barnicle asserted that McCain "has to figure out, you know, does he remain true to himself, in which he would obviously have immense appeal to independents in the fall, or does he play to the band right now in the spring." Barnicle also claimed that while in "most campaigns," "Republicans begin on the right for their campaign and come to the middle for the fall," McCain is "in the middle and he has to swing right for the primaries." In fact, McCain has already "play[ed] to the band" by shifting rightward on high-profile issues such as immigration and taxes. Further, a prominent study by political science professors Keith Poole and Jeff Lewis indicates that his Senate record is not "in the middle." McCain has also rejected the idea that he is a moderate or "in the middle," instead asserting that he is a "mainstream conservative."
Poole and Lewis' study ranked McCain as the eighth most conservative member of the 110th Senate, the second most conservative member of the 109th Senate, and the fourth most conservative member of the 108th Senate. The Poole-Rosenthal ratings system, developed by Poole and political science professor Howard Rosenthal and known as NOMINATE, has become widely used among political scientists (see here for a list of academic studies that have used the Poole-Rosenthal system to evaluate legislative votes in both the U.S. and other countries). The system uses every non-unanimous vote cast by every legislator to determine his or her relative ideology.
In a February 7 speech at the Conservative Political Action Conference, McCain asserted that he is "proud to be a conservative," adding that his "record in public office taken as a whole is the record of a mainstream conservative." From the speech:
I am proud to be a conservative, and I make that claim because I share with you that most basic of conservative principles: that liberty is a right conferred by our Creator, not by governments, and that the proper object of justice and the rule of law in our country is not to aggregate power to the state but to protect the liberty and property of its citizens. And like you, I understand, as Edmund Burke observed, that "whenever a separation is made between liberty and justice, neither . . . is safe."
While I have long worked to help grow a public majority of support for Republican candidates and principles, I have also always believed, like you, in the wisdom of Ronald Reagan, who warned in an address to this conference in 1975, that "a political party cannot be all things to all people. It must represent certain fundamental beliefs which must not be compromised to political expediency or simply to swell its numbers."
I attended my first CPAC conference as the invited guest of Ronald Reagan, not long after I had returned from overseas, when I heard him deliver his "shining city upon a hill" speech. I was still a naval officer then, but his words inspired and helped form my own political views, just as Ronald Reagan's defense of America's cause in Vietnam and his evident concern for American prisoners of war in that conflict inspired and were a great comfort to those of us who, in my friend Jerry Denton's words, had the honor of serving "our country under difficult circumstances." I am proud, very proud, to have come to public office as a foot soldier in the Reagan Revolution. And if a few of my positions have raised your concern that I have forgotten my political heritage, I want to assure you that I have not, and I am as proud of that association today as I was then. My record in public office taken as a whole is the record of a mainstream conservative. I believe today, as I believed twenty-five years ago, in small government; fiscal discipline; low taxes; a strong defense, judges who enforce, and not make, our laws; the social values that are the true source of our strength; and, generally, the steadfast defense of our rights to life, liberty and the pursuit of happiness, which I have defended my entire career as God-given to the born and unborn.
Those are my beliefs, and you need not examine only my past votes and speeches to assure yourselves that they are my genuine convictions.
Several print publications have recently referred to McCain as a "moderate," despite McCain's record and his assertion that he is "proud to be a conservative":
- In a February 9 New York Times article, staff writers Michael M. Grynbaum and John Harwood wrote that the "fast-fading presidential dreams" of New York City Mayor Michael Bloomberg are "diminished by the success of Senator John McCain, a moderate candidate who has emerged as the Republican front-runner."
- A February 9 Associated Press article reported that Rep. Mike Pence (R-IN) "said he would counsel McCain, a moderate Republican, to pick a conservative as his running mate to gain the support of conservatives."
- A February 8 Washington Post article by staff writers Michael D. Shear, Chris Cillizza, and Glenn Kessler reported that when former Massachusetts Gov. Mitt Romney began his presidential run, he "looked like the ideal Republican candidate -- a conservative who seemed certain to face either McCain or [former New York City Mayor Rudy] Giuliani, both men whose moderate credentials would force them to run as centrists."
Media Matters for America has documented the broadcast and print media's habit of using the label "maverick" when discussing McCain.
From the February 12 edition of MSNBC's Morning Joe:
BRZEZINSKI: He does great with the crowd. But the question, Barnicle, I have for you about this is: In terms of John McCain trying to appeal to the conservative base, maybe even having the president putting his arm around him to help him with the conservative base, does he potentially alienate himself from independents and other Republicans who could go for someone like Barack Obama? Is there a scenario there, or am I too far down the road?
BARNICLE: No, I think that's the trick, that's the trick for John McCain. He has to figure out, you know, does he remain true to himself, in which he would obviously have immense appeal to a lot of independents in the fall --
BRZEZINSKI: Absolutely.
BARNICLE: -- or does he play to the band right now in the spring. I mean, most campaigns, they begin -- the Democrats begin in the left in the spring and have to come toward the middle for the fall. Republicans begin on the right for their campaign and come to the middle for the fall. He's in the middle --
BRZEZINSKI: Right.
BARNICLE: -- and he has to swing right for the primaries.
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Team Associated Caster Block Set (6°)
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text:
Titans quarterback Jake Locker practiced all week despite separating his left, non-throwing shoulder five days ago and is expected to not be limited during Sunday's game in San Diego. And he'll be joined by the Titans' best wide receiver, Kenny Britt , a least for a little while. Britt, who is a year removed from tearing an ACL, has undergone three knee surgeries in the past 12 months. But he appears ready to make his season debut after participating in all practices this week. Britt is expected to be on the field for somewhere between 15-25 snaps.
Fantasy Analysis:
Last week, we were burned by Adrian Peterson when it looked like he would be very limited against the Jaguars. Maurice Jones-Drew and Trent Richardson also saw more playing time than anyone expected, too. I don't know how the Titans will act, but maybe estimated snap counts are overrated.
I understand if you want to wait one more week on Britt and see how he looks. That's probably the route I would take if I owned him. But taking Britt's immense talent into account with the fact that Nate Washington banged up, I have no problem with some people starting him in three-receiver leagues. The matchup certainly doesn't scare me.


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text:
Breast Cancer Screening (Mammography, MRI & Ultrasound) Market & Forecast - Worldwide
|Renub Research
|英文 258 Pages
納期: 即日から翌営業日
|世界の乳癌スクリーニング(マンモグラフィ・MRI・超音波)市場・予測 Breast Cancer Screening (Mammography, MRI & Ultrasound) Market & Forecast - Worldwide
|出版日: 2014年09月09日
|ページ情報: 英文 258 Pages
Breast cancer is the most common cancer among women in both the developed and developing world. Worldwide Breast Cancer Screening Market was in double digit Billion US$ for 2013. United States is the leading market for breast cancer screening globally. China is expected to maintain its 2nd position in the forecasting period due to hefty number of breast cancer cases. Worldwide Breast Cancer MRI Screening Market and Breast Cancer Ultrasound Screening Market are also growing year on year.
Worldwide Breast Cancer Screening population is expected to be little less than 250 Million by 2018. For 2013; China contributes the largest pool of patients followed by United States. Both these countries control double digit population share. Brazil, Japan and Germany occupy the 3rd, 4th, & 5th position respectively.
This is our 4th report on Cancer Sector. Renub Research study titled "Breast Cancer Screening (Mammography, MRI & Ultrasound) Market & Forecast - Worldwide" analyzes the worldwide market for breast cancer mammography screening market, Breast cancer MRI screening market and breast cancer ultrasound screening market. This report studies separate comprehensive analytics for the 20 countries: United States, Canada, European Countries (United Kingdom, France, Germany, Italy, Spain, Netherlands, Norway and Switzerland), Asian countries (India, China, Japan, Korea, Singapore, Thailand, Malaysia and Brazil), Australia and New Zealand.
Annual estimates and forecast are provided for the period of 2014 through 2018. A six year historic analysis is also provided for these markets. This 258 page report with 252 Figures and 14 Tables provides a complete analysis of top 20 countries of worldwide breast cancer screening market. All the 20 countries in the report have been studied from 7 viewpoints.
This report is built using data and information sourced from proprietary databases, primary and secondary research and in-house analysis by Renub Research team of industry experts.
Primary sources include industry surveys and telephonic interviews with industry experts.
Secondary sources information and data has been collected from various printable and non-printable sources like search engines, News websites, Government Websites, Trade Journals, White papers, Government Agencies, Magazines, Newspapers, Trade associations, Books, Industry Portals, Industry Associations and access to more than 500 paid databases.