text:
Octreotide, Tamoxifen, and Chemotherapy in Treating Women With Breast Cancer
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RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining hormone therapy with chemotherapy may kill more tumor cells.
PURPOSE: Randomized phase III trial to study the effectiveness of tamoxifen, octreotide, and chemotherapy in treating women who have stage I or stage II breast cancer.
|Breast Cancer
|Drug: cyclophosphamide Drug: doxorubicin hydrochloride Drug: octreotide pamoate Drug: tamoxifen citrate
|Phase 3
|Study Type:
|Study Design:
|Primary Purpose: Treatment
|Official Title:
|A Clinical Trial to Evaluate the Benefit of Adding Octreotide (SMS 201-995 PA LAR) to Tamoxifen Alone or to Tamoxifen and Chemotherapy in Patients With Axillary Node-Negative, Estrogen-Receptor-Positive, Primary Invasive Breast Cancer
|Study Start Date:
|May 1997
|Study Completion Date:
|March 2006
OBJECTIVES: I. Determine whether the addition of octreotide pamoate to tamoxifen alone or to tamoxifen and chemotherapy improves the disease free survival of patients with primary invasive breast cancer with estrogen receptor (ER) positive tumors and histologically negative axillary lymph nodes or histologically negative sentinel lymph nodes if participating in NSABP B-32. II. Determine whether the rate of endometrial cancer associated with tamoxifen is altered by the concurrent administration of octreotide pamoate. III. Determine whether the addition of octreotide pamoate to tamoxifen decreases the rate of opposite breast cancer more than tamoxifen alone. IV. Evaluate the incidence of gallstone formation (including the development of symptoms and complications of biliary tract disease), hyper and hypoglycemia, hypothyroidism, and vitamin B12 deficiency in patients treated with octreotide pamoate in comparison with patients not treated with octreotide pamoate.
OUTLINE: This is a randomized study. Patients are randomized into one of four treatment arms. Arm I: Patients receive oral tamoxifen (TMX) daily continously for 5 years. Lumpectomy patients receive breast radiotherapy following recovery from surgery. Arm II: Patients receive TMX as in Arm I and octreotide pamoate (SMS 201-995 pa LAR) intramuscularly (IM) every 21 days for 4 doses, followed by octreotide pamoate IM for 28 days for 23 additional doses. Lumpectomy patients receive breast radiotherapy following recovery from surgery. Arm III: Patients receive doxorubicin (DOX) IV and cyclophosphamide (CTX) IV every 3 weeks for 4 courses and TMX as in Arm I. Lumpectomy patients receive breast radiotherapy after recovery from chemotherapy. Arm IV: Patients receive DOX and CTX as in Arm III, TMX as in Arm I, and octreotide pamoate as in Arm II. Patients receive TMX and octreotide pamoate on day 1 of first course of chemotherapy. Lumpectomy patients receive breast radiotherapy after recovery from chemotherapy.
PROJECTED ACCRUAL: Total accrual of 3,000 patients will be acrrued for this study over 5 years.
|Ages Eligible for Study:
|Child, Adult, Senior
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
DISEASE CHARACTERISTICS: Histologically confirmed Stage I, IIA or IIB invasive adenocarcinoma of the breast with T1-3, pN0 and M0 classification Must have undergone total mastectomy or lumpectomy followed by an axillary dissection or sentinel node resection if participating in NSABP B-32 Histologically negative axillary lymph nodes OR Histologically negative sentinel lymph nodes if participating in NSABP B-32 Lumpectomy and axillary dissection acceptable only if margins of resected specimen are histologically free of invasive tumor or ductal carcinoma in situ and other dominant masses within the ipsilateral breast remnant are histologically confirmed to be benign Additional operation after resection is allowed in order to obtain clear margins No bilateral malignancy of the breast ER positive tumors as defined by at least one of the following: At least 10 fmol/mg cytosol protein by either dextran-coated charcoal or sucrose density gradient methods Positive or not definitely negative results by the enzyme immunoassay method (EIA) or by immunocytochemical assay No more than 63 days from time of initial cytologic or histologic diagnosis of breast cancer till randomization No bone metastases (confirmation must be made for those with skeletal pain) Tumor must be no greater than 5 cm in its greatest dimension for patients who are treated by lumpectomy and axillary dissection Hormone receptor status: Estrogen receptor positive
PATIENT CHARACTERISTICS: Age: Not specified Sex: Female Menopausal status: Not specified Life expectancy: At least 10 years (excluding diagnosis of cancer) Performance status: Not specified Hematopoietic: WBC at least 4,000/mm3 Platelet count postoperative at least 100,000/mm3 Hepatic: Bilirubin normal SGOT/SGPT normal Renal: Creatinine normal Cardiovascular: No cardiac disease that would preclude the use of doxorubicin (for patients who are to receive adjuvant chemotherapy in this study), including: Myocardial infarction Angina pectoris that requires antianginal medication History of congestive heart failure Arrhythmia associated with concurrent heart failure or cardiac dysfunction Valvular disease with cardiac compromise Cardiomegaly or ventricular hypertrophy unless left ventricular function is within normal limits Poorly controlled hypertension Other: No prior invasive breast cancer or ductal carcimoma in situ No systemic disease that would preclude patients from any part of study No history of symptomatic gallbladder or biliary tract disease unless patient has undergone cholecystectomy No ulceration, erythema, infiltration of the skin or underlying chest wall (complete fixation), peau d'orange, or skin edema of any magnitude No prior nonbreast malignancies in past 10 years except: Squamous or basal cell carcinoma of the skin that has been effectively treated Carcinoma in situ of the cervix that has been treated by operation only Lobular carcinoma in situ of the ipsilateral or contralateral breast treated by segmented resection only No psychiatric or addictive disorders Not pregnant or nursing Negative pregnancy test
PRIOR CONCURRENT THERAPY: Biologic therapy: No prior biologic therapy for breast cancer Chemotherapy: No prior chemotherapy for breast cancer No prior anthracycline therapy for patients who are to receive adjuvant chemotherapy in this study Endocrine therapy: No prior endocrine therapy for breast cancer Must discontinue any sex hormonal therapy before prior to and during study Radiotherapy: No prior radiotherapy for breast cancer No breast radiation therapy before randomization for patients who receive lumpectomy Surgery: See Disease Characteristics At least 2 weeks since last surgical procedure Other: No concurrent cyclosporine therapy No concurrent heparin or warfarin anticoagulation therapy
Please refer to this study by its ClinicalTrials.gov identifier: NCT00002967
Show 108 Study Locations
|Study Chair:
|Richard G. Margolese, MD
|Jewish General Hospital
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
|ClinicalTrials.gov Identifier:
|NCT00002967 History of Changes
|Other Study ID Numbers:
|Study First Received:
|November 1, 1999
|Last Updated:
|June 20, 2013
Keywords provided by National Cancer Institute (NCI):
stage I breast cancer
stage II breast cancer
invasive ductal breast carcinoma
Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
Liposomal doxorubicin
Antibiotics, Antineoplastic
Antineoplastic Agents
Topoisomerase II Inhibitors
Topoisomerase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
Antirheumatic Agents
Antineoplastic Agents, Alkylating
Alkylating Agents
Myeloablative Agonists
Estrogen Antagonists
Hormone Antagonists
Hormones, Hormone Substitutes, and Hormone Antagonists
Antineoplastic Agents, Hormonal
Selective Estrogen Receptor Modulators
Estrogen Receptor Modulators
Bone Density Conservation Agents
ClinicalTrials.gov processed this record on June 23, 2017


text:
Kevin Stewart is an Academy graduate who has enjoyed a smooth transition to life in the first-team squad under the guidance of Jürgen Klopp.
The boyhood Reds supporter arrived on Merseyside from Tottenham Hotspur in the summer of 2014, and was initially viewed as a full-back capable of playing on either side of the defence.
But, when Connor Randall was taken ill prior to a fixture against Norwich City in December 2014, the former Spurs man was deployed in a central midfield role - and immediately impressed.
A month later, Stewart joined League Two outfit Cheltenham Town on a month-long loan before returning to Anfield on February 2.
The defender was on the move again at the end of March, heading to Burton Albion for another spell of first-team football.
That loan stint was punctuated with a dramatic winning goal against Cambridge United on the final day of the 2014-15 season, which saw Burton seal the League Two title.
In July 2015, Stewart agreed a loan switch to League One outfit Swindon Town, but he was recalled by Klopp in January with injuries mounting at Anfield.
After impressing in training, he was subsequently given a first-team debut against Exeter City in the FA Cup, a game which saw a young team earn a 2-2 draw and a home replay.
Stewart featured again as the Grecians were beaten 3-0 on Merseyside, and in the subsequent fourth-round double-header against West Ham United - a 0-0 home draw and cruel 2-1 defeat in London.
Five days later, the midfielder's progress was rewarded with a Premier League debut as Aston Villa were thrashed 6-0 at Villa Park on Valentine's Day.
And he made six further league appearances across the remainder of 2015-16, establishing himself as a crucial member of Klopp's squad.
On November 8, 2016 Stewart put pen to paper on a new long-term deal with the club.

subset: commoncrawl


text:
Software vendor Oracle Corp. Monday announced that it is working with Wells Fargo & Co. to integrate Oracle's B2B (business-to-business) Exchange software with the U.S. financial services company's electronic marketplaces.
The tie-up should provide Oracle Exchange users with a range of Internet-enabled B2B commerce services, including credit, electronic payment and settlement, as well as digital certificate-based trust services, Oracle said in a statement. Users will also have access to international trade technologies such as online letters of credit.
Wells Fargo expects to offer users of OracleExchange.com and Oracle-powered exchanges services that are part of its WellsXchange offering which allows members of e-marketplaces to conduct domestic and international transactions without leaving a marketplace site.
"Services to buyers and sellers are through Oracle Exchange, right on the market site," said Deborah Ball, e-business manager, wholesale Internet solutions at Wells Fargo. "So it's more efficient and faster."
Ball sees the partnership between Oracle and Wells Fargo as a significant move in changing B2B commerce. "I think financial services are crucial to the growth of B2B markets because e-markets really enable buyers and sellers to transact business online," she said. "It's quick, efficient and convenient for them."
Wells Fargo is part of the Oracle Exchange Partner Initiative (OEPI) that provides services for Oracle Exchange operators, suppliers and buyers worldwide.
Oracle, based in Redwood Shores, California, can be reached on the Web at http://www.oracle.com/. Wells Fargo, based in San Francisco, California, can be reached on the Web at http://www.wellsfargo.com/.


text:
1 fryer chicken, trimmed of fat, cut into bite size
3 stalks of lemongrass (remove the tough part)
1/4 clove of garlic
2 – 10 birds eye chilies or Thai Dragon
1 T garlic oil
1 T shallot oil
1 T sugar
1/2 tsp. salt
In food processor, turn spice into paste. Mix paste
with cut up chicken pieces. This step can be done a
day ahead.
1/4 C fish sauce (there is no substitute here)
1 T dark soy sauce
1/2 C chicken broth or water
Have ready: 1/4 C brown sugar
In a hot wok with high heat, drizzled with 2 or 3 T
oil, sear the chicken pieces. Do it in 3 or four
batches. This is an important step. Remove each batch.
Let wok heat up again before you add more chicken. If
it burns a little bit, that's good. When the last
batch is removed from wok, sprinkle in the brown sugar
and let it caramelize. Don't worry about the smoke,
just don't burn the sugar. Return the chicken to the
wok for the next 3 to 5 minutes. Keep stirring. Then
add liquid. Stir well. Cover and cook for 7 to 10
Uncover. The cooking process is done when the sauce
clings to the meat and is not runny.
Garnish with scallions and cilantro (1/2 C mixed)
Tip: When a recipe calls for searing, use the highest
heat possible. Never crowd the pan.


text:
Now it's time to enjoy the bounty. The Waterloo Community Garden at the corners of Swift Street and E. Wright Ave., behind Lake Country Christian Church and the water tower, needs volunteers to harvest the produce and take care of the plot through the end of the season. Garden Manager Jennifer Dressing tells us a project like this draws people from all over the village who are interested in fresh food.
They have summer squash, cucumbers, eggplant, 4 different kinds of peppers, broccoli, cauliflower, herbs, and some tomatoes. As the need arises they will use more of the parcel.
You can reach Dressing at (315) 220-8127 to volunteer.


text:
///M3 Forum
The BMW E46 ///M3 is the M version E46 and puts out an amazing 333 HP and 262 lb-ft of torque at stock specs! There are an amazing amount of modifications for both the coupe and convertible models so read up and get started modifying your cars today!
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Registered User
Join Date: Jan 2012
Location: Los Angeles
Posts: 2
My Ride: M3 Vert
The Most Horrible Noise My Car Has Ever Made! .. .Mp3 Attached!
I was, hoping that maybe some of you experienced guys could help me out. I have a 2001 M3 vert. With 61,000 miles When I pulled into my garage tonight, I heard a strange popping & groaning sound coming from underneath the car. I pulled out the voice recorder on my phone and kneeled down on the driver side in right in front of the back tire just in time to catch the car make the most horrible noise (you will hear this in the first 5 seconds of the recording, but it spudders and pops for like 2-3 more minutes) The car was off and keys out of ignition, and yes I am up on all of my matinince, fluids ect... No codes from the peake. The only thing that I have noticed lately is that my gas mileage is pretty bad - approx 12-14mpg. I was wondering if it could be the fuel pump heading on its way out? I am really hoping you guys can give me a hand with this. Thanks.
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A window into health in California.
« Full episode for
Feb 15-17, 2013
Huge advances in medical science are letting people living with HIV rekindle dreams, including those of having a family. A San Francisco program that's helped HIV-positive women have babies for years has recently launched a program thought to be the first of its kind. The program helps straight HIV-positive men become dads. Reporter: Mina Kim
Never miss an episode of The California Report.
The California Report is a production of KQED Public Radio.
Generous support for The California Report is provided by:
Eric and Wendy Schmidt |
The James Irvine Foundation |
Barracuda Networks |
The California Endowment |
California HealthCare Foundation |
Bracamontes & Vlasak, P.C. |
Blach Construction |
The Westly Foundation |
Digital Foundry


text:
Using a built-in dishwasher as a stand alone
We were recently given a built-in dishwasher that we would like to install, but our kitchen is far too small, and we currently don't have the means to re-do our cabinets to accomodate the built-in dishwasher. I've read that it is possible to use the built-in dishwasher as a freestanding or stand alone dishwasher. So my questions are:
1. Is that true?
2. If true, HOW would I go about converting the built-in dishwasher to a freestanding one?
You would need to build a cabinet that you could roll around, and would have to get the connection kit for the hoses, that allows it to connect to the faucet, then also install a cord that would allow you to connect it to an outlet, when needed. If you own the place, taking out a wall like we did, to expand our Kitchen into the dining, allowed us to move the fridge over, so the portable dish washer could sit between the sink and fridge.
If renting, you could still run into an issue of no space to place the unit, when not in use.
Sorry, I think I may have miscommunicated what I wanted to do. Basically, I want to take my built-in dishwasher, and instead of placing it under the countertop by my sink, I want to have it sit in a different part of my kitchen. I don't want to have to hook it up to the faucet every time I run it. I would like it to sit as a stand alone appliance, but have it run like a built-in dishwasher as opposed to a freestanding/stand alone dishwasher. Could I just buy extension tubes or something?
There is a reason why they make portable dishwasher units, so you do not have to buy a base cabinet or make a frame that the under counter unit will fit into, and then have to buy the parts to make the under cabinet unit able to hook up to the hot water line, and then you have to figure out a way to plumb it into the waste line, and vent.
It just becomes too much work to create a unit that would sit away from the sink & waste/water lines inside the base cabinet, but could be done, if you know what you are doing.
Just easier to leave it where it is, or get a portable unit as I stated before.
you can not use a built in dishwasher as a "stand alone". As greg said you will need some sort of cabinet around it as it will not stand on its own without tipping over. Then you would have to plumb it and wire it.
Can it be done? Sure! Is it practical? No.
Mine stood on its own, when I removed it...
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My Nonprofit Reviews
Review for Effortz Foundation Inc, East Falmouth, MA, USA
As the manager of the nation's largest workplace giving campaign, I see a lot of nonprofits doing great work in every possible cause, in nearly every possible location. I am impressed with the dedication and passion of the board of EfforTZ and the work they are doing to change individual lives. I give a large portion of my own personal donation to EfforTZ each year, and I am certain they make the best possible use of my donation.
More Feedback
How does this organization compare with others in the same sector?
Quite well
How much of an impact do you think this organization has?
A lot
Will you recommend this organization to others?
When was your last experience with this nonprofit?


text:
Double standards in Bali
TWO INDONESIAN words seem useful in describing the relationship of Australians to the island of Bali.
Halus, meaning refined, can be applied to the interest in the fine paintings, the dances and the rich spiritual life of Bali, as well as its dramatic scenery of volcanos, terraced rice fields, jungles and palm-fringed beaches.
Its antonym, kasar, or crude, goes with the blokey (and blokette) milieu of Kuta Beach and other mass tourism locales, featuring excessive drinking, recreational drugs and sexual adventure.
Apart from a few wafty souls, most of us, to be honest, hover between halus and kasar on our excursions to the much-proclaimed paradise, enjoying both the traditional art and the cosmopolitan resort culture.
Next Friday, the Australian consulate-general in Denpasar will hold a memorial service for the moment five years ago when a dreadful crime interrupted this ambiguous idyll: the bombing of two nightspots at Kuta by Islamic extremists, which killed 202 people including 88 Australians.
But what have we, and the Balinese, learnt from this experience, which was reinforced in October 2005 by a second round of bombings, which killed 23 people.
A new book on Bali, Under the Volcano, by the veteran foreign correspondent Cameron Forbes, implicitly reminds us that the bombings could have triggered a hellish communal bloodbath.
Building on the work of scholars such as Adrian Vickers and the US academic Geoffrey Robinson, he portrays a society in a delicate psycho-social balance, trying to contain internal caste and political divisions and fend off pressures from outsiders, and always aware of a treacherous geology.
We are not quite a century away from Bali's last puputan - the ritualised charge to the death against an overwhelming enemy - when thousands of men, women and children in the Klungkung kingdom went out with their raja, armed only with their sacred daggers, against the machine-guns of the Dutch Army.
Just over 40 years ago, Balinese rose up at the instigation of the Indonesian Army, and slaughtered about 80,000 of their own for real or rumoured connections to the Indonesian Communist Party.
The island has a very bloody history, in which mass killing is often read as the divinely ordained consequence of impurity. After the Bali bombings, when the tourist dollars stopped flowing, the Balinese could easily have turned on the outsiders from other parts of Indonesia.
Instead, Bali has bounced back. Tourism is back to pre-bombing levels, though with fewer Australians. Forbes reports a "core of optimism" that Bali's culture will cope both with the foreigner influx and the weakening of its own Hindu caste hierarchy.
Are we rising above the bombings? A curious media debate suggests we are still struggling.
Early last month, the Indonesian Supreme Court rejected a plea for a case review by the three convicted Bali bombers, Amrozi, Ali Ghufron and Imam Samudra.
This ended their final chance for an appeal through the Indonesian legal system. Only commutation by the President, Susilo Bambang Yudhoyono, can prevent them going before a firing squad in coming weeks.
Their lawyer has said the three will not plead for presidential clemency themselves.
Amnesty International, which opposes the death penalty in all circumstances, has suggested we do it for them. The result is an outcry against Amnesty by some bereaved families of the Bali victims, whipped up by the Murdoch tabloids.
Amnesty and others point out that Australia is now in the position of approving the application of Indonesian law in the case of the Bali bombers, but opposing it in the case of the nine drug couriers from Australia caught in Bali, six of whom received death sentences.
In 2006, when the young Australian drug mules were sentenced, the Prime Minister, John Howard, admitted the double standard.
The Foreign Affairs Minister, Alexander Downer, last week confirmed that Australia would not be lodging any appeal for commutation in the Bali bombing case.
Yet Amnesty, and Forbes in his book, make a compelling case for doing so, on the pragmatic ground it would bolster clemency appeals for Australian drug convicts (unless you share the tabloid view that all drug smugglers should be shot or hanged). Others point to the loss of potential intelligence against other terrorists, should the convicts change their thinking during imprisonment and start to talk.
It would also be a halus way of denying the terrorists a kind of victory, their martyrdom. So far in the war on terrorism, has not the West largely done what al-Qaeda and Jemaah Islamiah were trying to provoke?
When news happens: send photos, videos & tip-offs to 0424 SMS SMH (+61 424 767 764), or us.
Did you know you could pay less than $1 a day for a subscription to the Herald? Subscribe today.


text: "I work for a charity, doing something I love that I think is important. But I don't earn much. I grossed $35,000 last year. According to an entry in Wikipedia, that makes me lower middle class, but I just did my tax returns, and now I feel poor. "I believe my federal with-holding was done correctly, but I still had to write a big check to the federal government, and my situation with my state government is an even worse problem. "I had more than $12,000 in medical expenses last year, mostly dentistry. But after spending the better part of two days reading through tax instructions, applying all the rules, and adding up all the numbers, I just missed having enough qualifying expenses to itemize. "It doesn't seem that it would have made much difference anyway, even if I had barely qualified. "I also found, in one small paragraph in the tax instructions, something indicating that I probably qualify for a fine for not doing enough federal withholding. But everyone I've consulted seems to agree that my with-holding was done correctly. I just owe more money. And somehow, when I do the numbers, it still seems that I qualify for this fine. "The situation with my state taxes is even worse. My state has no mechanism for doing my with-holding because the non-profit for which I work is headquartered in another state. The company that does the payroll for my employer expressed despair when they learned where I live. Apparently my state is notorious for this problem. And the tax collection bureaucrats in my state won't do anything to help fix it. As a result . . . "No state with-holding is done for me. I have to pay it all in one lump sum at the end of the year, or make quarterly estimated payments. The forms involved are mind-numbingly complex, the worst I've ever seen. And I can't help fearing that the state will fine me for all this, even though the problem is theirs, and not mine. "I suppose I'm at the point where I need to hire professional help. But that's expensive, with no guarantee that I'll actually owe less tax as a result. I can barely pay the bills I already have . . . "When I added my total tax payments for the year and my total medical expenses, the result was shocking. These two expenses consumed more than half of what I made in 2007. And it wasn't as if I had any really serious medical problems. Plus, I actually have health insurance, but my out-of-pocket was still huge, and most of it had to be paid with credit cards, at a very high rate of interest. "I can't help thinking that this whole set-up is a backdoor corporate welfare scheme for the credit card companies. But it gets worse . . . "What if I added up my sales taxes, and my property taxes? My net income would look even worse. And what about all the hidden tariffs and excise taxes and corporate taxes that are passed on to me in the cost of the things I buy? Then there's the inflation tax. I know the government has been expanding the money supply. All of my costs are rising, but my income isn't. "I also know that the government has distorted the health care market, causing costs to soar, and I know that the government was responsible for the housing bubble too, making housing unaffordable for me, even though I'm supposedly middle class. "At this rate, how will I ever save for retirement? Social Security isn't enough to live on, and it's in trouble anyway. "The politicians constantly claim they're doing things to help people, but I feel like they're crushing me. "All of this makes me see the value of Ron Paul's health care bill. His tax credit would make a huge difference for me. And I'd like to be able to save more in my HSA for when I have real health care problems, and not just the minor things I had last year. "I hope Downsize DC can get this bill passed, and cut the size of government in general. I really need it."**** Well, we think that says it all. Please send another message to Congress asking them to pass Ron Paul's health care bill. Please also help us grow stronger by contributing just a few dollars a month: $5, $10, $15, $20, or $25. All of those amounts equal less than a dollar a day. Please start a monthly credit card pledge to make us grow. You can do so here. Or, you can make a one-time contribution to help us make budget for April. We need just four more $100 contribution to win the $1,000 matching donation from Jack Mullen. You can contribute here. Thank you for being a part of the growing Downsize DC Army. Jim Babka President DownsizeDC.org, Inc.


text:
A friend recently asked me what my backup strategy is for the large number of photo's I've taken since my daughters birth. I used to be pretty comfortable with 'Time Capsule' as an answer but with the falling cost of cloud storage and growing number of sync services, a pure Time Capsule strategy feels a little antiquated. If I were discussing this with a client, I'd point out the obvious omission of an offsite backup.
As such, I decided to move my iPhoto library to a cloud-based service.
First step was to check it was possible: A quick search showed many others have done this, and many have written guides. Great.
Next I checked the size of my iPhoto library – 40GB! How did that happen? I looked through the iPhoto folder structure to see if iPhoto was doing something crazy. I tallied the folder sizes in the Masters which seem like the right ball park, so ok, maybe I've been a touch overzealous with the shutter button. Fine, I'll deal with this later.
Now I knew my space requirements, I needed to choose a service. I started by looking at Dropbox, who charge $9.99 per month for 100GB – this seemed a little pricey, so next port of call was Google Drive – 100GB for $4.99 a month? Done.
Now to get syncing! With a fresh installation of the Google Drive app on the Mac and quick file sync, all seemed as expected, so I followed the cautious advice of other bloggers and copied my iPhoto Library to Google Drive.
All seemed well at first, but after a while I noticed the nice animated icon in the Mac taskbar had stopped spinning. Umm, que? Mouse over the icon and I get the spinning beach ball. Forever. I restarted Google Drive and put it down to stage fright, but the same thing happened again. A search turned up several potential solutions to this, mostly blaming a Mac OS bug, but unable to find a resolution, I downgraded my Drive storage and switched to Dropbox.
I purchased the 100Gb from Dropbox, but bought a year in advance ($99 – 17% off) and also paid using my Paypal account, so it didn't feel like real money anyways 🙂 Checked the Dropbox app – 103.1GB free. Right then!
With a greater confidence in Dropbox's syncing capabilities, I threw caution aside and moved my iPhoto library into the Dropbox folder – much quicker than waiting for 40GB to copy across. What's the worst that can happen?
Note: I also switched the power settings on the Mac to never sleep the computer because I wanted it to sit there and do a complete sync.
Over the next few days I checked back on Dropbox's progress – seemed to be progressing nicely at first, and then I started noticing that it was getting closer to the 40GB mark, but seemingly still had a high number of files to sync…strange. My first thought was that Mac OS filesystem was doing some kind of compression under the covers, but as I passed the 50GB, 60GB, 70GB mark, something was obviously wrong.
When the sync had finally finished, Dropbox was 80% utilised. So, what the huh happened there? The disk still says 40GB, but Dropbox says 80GB. A quick search, and I found the answer here. Was this originally an iPhoto 10 library? Yes. Was this upgraded to an iPhoto 11 library? Yes. Does Dropbox support Symlinks? No.
If you're not au fait with the term, symlink is short for 'Symbolic Link', which is basically a file which points to another file or folder. When you open that symbolic link, you actually end up opening the file or folder it points to. They are good because you can use two different names for the same file or folder. But they're bad if you're cloud service doesn't support them.
Fortunately, the aurelio article nicely summarises the workaround which removes the symbolic links, cleans up all that unnecessary Dropbox space and (hopefully) keeps iPhoto working in the process. As I've written this, I've been watching Dropbox gradually tidy itself up, with the percentage used slowly dropping down to the expected 40%. I'm at 68.1% and falling. Fingers crossed!
Wrap-up notes:
1. The top tip for anyone migrating an iPhoto library to a cloud service is to check, and fix, any symbolic links in their library before making the move – the engineer inside me shudders at the 40GB of duplicated data I created in my Dropbox account. Apparently this isn't a problem if you started with iPhoto 11, but definitely check first anyways.
2. Whether the issues with Google Drive were related to my specific version of Mac OS X Mountain Lion, or whether they were actually related to the symlinks, I don't know, but for the cost associated with Google Drive, I definitely wouldn't suggest everyone rules it out.
3. Unless you want your iPhoto library downloaded onto every computer that you sync to, don't forget to configure the Selective Sync settings everywhere else.
4. I'm only syncing my iPhoto library with one Mac and I don't know how well this technique works if you're syncing and modifying the library with two Macs. My gut says dragons be here.
5. If you use Time Capsule, I recommend switching it off whilst all this moving and symlink fixing activity is going on. I can imagine it would get quite irate at the types of changes I've made.
6. Google Drive isn't very to-the-minute in reporting your free space. If you delete a bunch of files, it takes some time to update the available storage displayed. Strange.
7. Lifehacker have a great article comparing Google Drive and Dropbox. I'd read this if you're trying to justify the additional spend.
8. Other guides rate this process as 'Easy'. I'd actually bump that up to 'Medium' if you're not a computer aficionado
Update: The Dropbox cleanup sync took about 5 hours in total, and following this my iPhoto library still works fine. Phew!
Update: I've since moved away from Dropbox for iPhoto backups, as detailed here.


text:
average rating: -- / 10
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After you sequence PuTTYgen you might go to a display someplace you could have a pair of cream of the crop: Produce, to build a whole new public/private pitch brace, or maybe Put in for you to burden within the continuing living personal crucial. This will enable a good assailant toward pretend that for being an individual for almost any volume of hope conference. Considering magazines, they remain a superb strategy for getting to made known with a massive number of individuals. | After you boast gone for the sort of main you would like, moreover the effectiveness of the real key, bear down on the Spawn option and also PuTTYgen will become the technique of truly cranking out the true secret. Former, a move forward piece motivation look as well as PuTTYgen force request that you walk the computer mouse surrounding to get chance. 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I wanna cook
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Whatever it is, sell a few portions on Super Marmite! It's a great way to interact with your local community and to get real feedback on your cuisine :)Post a meal


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Today's data center is rife with duplicated data. The duplication ranges from the same operating systems running across hundreds of servers, to matching database fields, to test and development copies of data, to multiple copies of the same email attachments saved across multiple user's home directories. IBM industry-leading inline deduplication solutions reduce or eliminate duplicate data to help organizations of all sizes protect all their data on disk-based storage more efficiently and manage the exponential growth of new data.
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Powerful IBM ProtecTIER® data deduplication solutions improve backup and disaster recovery operations while lowering operational costs and energy usage . ProtecTIER native replication technology enables the automated electronic replication of backup data between one or more data centers, remote offices and offsite storage locations for enhanced disaster recovery and business continuity. Eliminating the need to transport physical tape/cartridges lowers TCO by up to 96% and ensures that data can be recovered faster and more reliably, enabling systems to get back online quickly in the event of a disaster or major system outage.
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Fast, reliable and easy-to-deploy backup and recovery solution for growing small & mid-sized environments
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Feline Panther Bracelet
Designed by:
Difficulty: Beginner
Start by threading 1x Bicone, 1x BeCharmed bead and 1x Bicone on an eyepin, then loop the end as close
as possible to pull the beads tightly together.
Next thread on a single bicone on an eyepin, then again loop the end as close as possible to
the bead.
Repeat Step 2 making an equal amount of them to fit your wrist.
Connect them up (an equal amount on either side of the BeCharmed bead). Attach your
lobster clasp to one end and the chain extension on the other end.
Make sure you get the materials you need to create this design yourself! Click the button below to add everything you need to your basket in one go. You can edit the list too just in case you want to make more than one, or you already have some supplies at home.Get the items you need to make this


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The Millennium Acorn Gumball Machine
Perfect accessory for any adult that wants to have a little fun AND rot their teeth. We used to have one until my kids got old enough to get gum out without using money. It's now in storage until they are 18.
What kids would not love these Bubble Gum Eggs?Tags: candy, Yummy, gum, Bubble Gum EggsAdded 8 Years Ago from Bibelotshops


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By: GeoEx Staff on October 08, 2013
On Sunday, Nov. 10, acclaimed Buddhist scholar and GeoEx trip lecturer Dr. Robert Thurman will be appearing in conversation with Wanderlust editor in chief Don George at Cavallo Point in Sausalito, California. The duo will discuss the lessons Dr. Thurman has gleaned from his own sacred journeys and the notion that every journey, and every day, is a pilgrimage. The evening will begin with a reception from 5:00-6:00pm, where appetizers and drinks will be served. The conversation will take place from 6:00-7:15pm. This event is a benefit for Tibet House US. All proceeds from the $100 ticket will go directly to the organization's work in preserving Tibetan culture, and the cost is fully tax deductible for attendees.
To reserve your space at the event, please purchase tickets in advance.
Don George, Editor
Don George is Editor in Chief of Wanderlust: Literary Journeys for the Discerning Traveler. He has been Travel Editor for Salon.com and the San Francisco Examiner and Chronicle, as well as Global Travel Editor for Lonely Planet Publications. Don is the author of "The Way of Wanderlust: The Best Travel Writing of Don George" and of "Lonely Planet's Guide to Travel Writing." He has also edited eleven anthologies, including A Moveable Feast, The Kindness of Strangers, and An Innocent Abroad. E-mail him at [email protected].
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Join Date: Apr 2002
Posts: 2,450
Tuesday, January 16, 2007 at 10:14AM
The A-cone is OK for most people, the dimethicone is a PEG one so supposedly comes off OK, in any case it's low enough on the LOI to not be too much of a concern, so it could work. Just be careful because it also has wheat protein, one that some people seem to have problems with (but maybe you won't). If you plan to use this regularly there is a possibility that you may have to shampoo on occasion.
2A/3A, medium length, layered, colored dark/medium ash blonde - "CGer" since April '02.
"Converting the 'curlskeptics' one curly head at a time..." HWHC


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Last Activity: 08-31-06 10:07 AM
About Me
- About girlsrace2
- Biography
- Oh what to say....Im 20, really really into anything that has to do with cars and things like that...have questions? Just ask!
- Location
- Newark, Ohio
- Interests
- Cars, friends, listenin to music, racing, etc.
- Occupation
- Comission Sales
- Car 1
- 1990 Acura Legend
- Dont cry when a girl beats your ass in a race, it'll be ok
Yes I'm a girl and yes I can work on cars!
Hi...My name is Tacara..... :p
- Dont cry when a girl beats your ass in a race, it'll be ok
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You can walk around wearing advertisements on your head for some musician who should be paying you, or you can pop in a pair of subtle earbuds that also happen to deliver top-quality stereo sound and come with an inline remote and microphone. The newly-arrived Ultimate Ears 600vi Noise-Isolating Headset with Mic and Remote from Logitech fits the latter type and is compatible with a wide range of smartphones, tablets, notebooks and portable players.
The 600vi headset employs specially tuned, top-firing, balanced armature speakers and audio filters to deliver stereo sound with extended high-frequency response and awesome detail. The in-ear headphones come with five sizes of soft, ergonomic silicone eartips and two sets of memory foam tips. The assortment enables you to find a perfect fit for stability and comfort. A custom fit also impedes unwanted ambient noise while improving the bass response.
The earphones are not bad to look at either. With silver and black housing, a tangle-resistant cord and a right-ear piece that is easy to identify because it is uniquely red (alliterative with "right"), you'll be donning your Ultimate Ears to answer a call within a few of notes of the ring tone.
The in-wire mic and three-button remote enable you to make calls, take dictation, control music playback and adjust volume on compatible devices including smartphones and MP3 players. The 600vi works with the iPhone, iPod touch and iPad as well as Blackberry smartphones. (See the specification chart for more detailed information.) A hard plastic carrying case is included for storage.
|Design Type
|Driver Type
|Singe, top-firing armature
|Frequency Response
|20 Hz – 20 kHz
|13 ohms, 1 kHz
|115 dB SPL/mW, 1 kHz
|Noise Isolation
|Microphone Frequency Response
|200 Hz – 10 kHz Microphone sensitivity: -58 dBV/Pa
|Blackberry, iPhone, MP3 Players, Computers, Home Audio Systems and Gaming Consoles with standard 3.5mm jack
|Input Type
|Input Connector
|1/8 inch (3.5mm)
|Cable Length
|46 inch (116.8 cm)
|Note about Remote
|The remote and mic are supported only by iPod nano (4th and 5th generation), iPod classic (120GB, 160GB only), iPod touch (2nd, 3rd generation and 4th), iPhone 3GS, iPhone 4, iPad 2 and iPad. The remote is supported by iPod shuffle (3rd generation).
|Note about Audio
|Audio is supported by all iPod models. Requires latest iPod software. Volume control functionality not available with BlackBerry devices. Audio is supported by most music-enabled smartphones with 3.5mm jack.


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WRXtuners Member
Join Date: Aug 2008
Location: Louisiana
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Myself (09 WRX) spent hours and hours looking for "my" perfect exhaust. I went SPT, yes it is alittle louder than You Tube. DO NOT make your choice strickly by You Tube!! I am totally stocked with it, nice deep rumble, not too loud, no cabin drone. I have a buddy (08 WRX) that just got the TurboXS, and he does not like it TOO loud, funny thing was that he offered to trade me plus some cash. HAHA yeah right. My best advice of finding your perfect exhaust I recommend listening to as many as you can IN PERSON. Just my ¢02. Good luck on the pursuit in finding that exhaust.
^ That's what I have (HKS Carbon Ti) on my 07 WRX and it's pretty loud.
If 0 was a "quiet" exhaust and 10 was a "loud" exhaust, I'd classify:
Stock cat back = 1
SPT cat back = 5
HKS Carbon TI = 8
I don't know how else to describe it. The HKS Hi Power cat back is pretty loud. Let's just say that when my car is backed up against the house (still several feet away), when I turn the car on in the morning, it shakes the whole house and you can hear and feel vibrations throughout the entire house. It is also really easy to set off car alarms in parking garages. It's that loud
nice i like this. where you think a borla hush and greddy sp2 would go?
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