text:
Projection + Breast Augmentation Q&A
600CC Silicone Implants Look Small on Me
My first Ba I had 340cc overs mod profile and was unhappy as they looked too small. I had my 2nd ba 3 months ago and went for 600cc HP silicone under... READ MORE
Advice for Breast Augmentation Revision to Lessen Projection?
I had my breasts augmented two years ago. I was a 32 full B cup, breastfed two babies, and had VERY minor ptosis. My BWD is 12.5, the implants I... READ MORE
5'9" and Lean & Atheletic. Desiring B cup. 255 cc or 285 cc? (photos)
I am 5'9", 130 lb, wear 34A but do not fill, BWD 12 cm, band width 33.5". BA is scheduled for 5/20. Desire small implant for active lifestyle &... READ MORE
How Much Difference is There Between HP Vs Mod + Silicone Implants?
I have decided to undergo lollipop mastopexy along with breast augmentation. I am 5'4 125-130lbs wearing 34C-34D bra with good amount of tissue.... READ MORE
Saline or Silicone for Someone with Adequate Breast Tissue?
Getting BA done next month.My doctor usually recommends silicone because most of his patients have an A cup.After my exam, he said I could go with... READ MORE
Changing implant profile for more defined cleavage? (photo)
I am 2 months post op with 280cc anatomicals. My current implants are moderate profile. My PS actually got me almost exactly to the wish picture I... READ MORE
Would It Be Possible for Me to Have Low Profile Implants? (photo)
I'm interested in getting a very natural look and from what i've seen the lower profile implants look far more natural. i prefer a flatter look with... READ MORE
Any Hope for Nipple Projection if I Get Breast Implants? (photo)
In 2003 had a breast reduction with free nipple graph. I noticed mass amounts of skin coming off in healing process around and on my nipples. I Spoke... READ MORE
What is a Large Volume, but Low Projection Breast Implant Going to Do for Me? (photo)
I have a very broad chest with a bwd of 17cm. I am trying to decide what size implants to go with and I am confused as to the volume because at some... READ MORE
Small breast implants. Will they drop and project more in a few months? (photos)
My goal size was a C cup and I chose the 350cc high profile sub muscular. (I had to get 325 cc in one breast to even them out. I was a 32A before and... READ MORE
Can the Root/base of the Breast Be Altered?
I have shallow breasts w/ wide+tall "roots". My under bust measurement is 29", bust 35.5", and my cup volume is ~400cc (water replacement test). I... READ MORE
What is the Real Difference in Mod+ Versus HP? (photo)
I have Natrelle 15s in 286cc mod+ and I like the shape, but I am considering a revision because I want more fullness. Would this be achieved with... READ MORE
What Size Implant to Get Best Projection and Upper Pole Fullness? (photo)
I'm currently a saggy 34DD, very heavy as you can see. I'm looking for a great lift with upper pole fullness and projection. I want to stay the same... READ MORE
2 mths post-op 375cc moderate plus profile, silicone implants are small & flat. Minor projection & lack overall fullness?(photo)
Pre-op cup 34 A and I wanted full, natural and shapely results. I requested a full B to small C cup, but my surgeon (HE IS AWESOME btw) recommended... READ MORE
Is it possible for drop and fluff to have already occurred 2.5 weeks post op? (Photo)
Had breast op 3 weeksago am unhappy they are way to small than planned i know that most swelling has gone down they already started to get more shape... READ MORE
Too much projection: 285 HP textured Sebbin: 10.3cm base/5cm projection. Armpit incision. 18 mths PO. 31 y/o. Short 5'2." (photo
If I go MP 200cc (10.4 / 3.4 cm) or 220cc (10.8 / 3.5), will I lose the upper pole unnatural fullness without needing a lift or pocket revision? Don't... READ MORE
What Projection Should I Get? (photo)
The "look" I'd like to achieve: cleavage, upper pole fullness, slightly natural, not too much projection. Large D, 425+ CCs Silicone A PS recommended... READ MORE
425cc under the muscle implants. 1 week post op, will I get more projection once the implants settle? (photos)
I realize a week post op is very soon to be unhappy with results. With that being said, most women think they are too big right after surgery, I do... READ MORE
Can you help me decide whether to go with mastopexy alone or with implants? (Photo)
I'm 41, 148 pounds and 5' 3"..After breastfeeding 3 kids and a 60 lbs. Weight loss im embarrassed and don't feel sexy naked. Currently 38C in bras.... READ MORE
Can I Avoid a Lift? (photo)
I am happy with the size of my Areola, and their placement on my breast. I am also happy with my over all breast shape. All I want is for my breast to... READ MORE


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NYC Tries GPS to Track Snowplows
(John Keefe, Transportation Nation) As meteorologists forecast more snow for New York City, City Hall plans to track where the streets are being cleared -- with GPS-equipped plows.
In the post-Christmas blizzard two weeks ago, cars, buses and ambulances were stranded throughout the city, and many streets remained unplowed for days. City officials and Mayor Michael Bloomberg were widely criticized for their response to the storm.
At a press conference this afternoon, Bloomberg said last time, "there was a discrepancy between information coming into and out of City Hall and what people were actually experiencing on the streets."
In a pilot project that will be tested if the snow flies tomorrow, GPS-enabled plows -- many of which are modified garbage trucks -- will roam the Brooklyn neighborhoods of Midwood, Flatbush and Ditmas Park, and also parts of Kensington.
Bloomberg said the tracking devices have become so cheap that eventually all 1,700 plows could be tracked, providing information not only on snow removal but also salting and trash pickup. Drivers of municipal vehicles in other cities, and in NYC taxi cabs, have fought such tracking systems as an invasion of their privacy.
Whether snowplow location information will be made public remains an open question. The Mayor's spokesman, Stu Loeser, said in a phone interview with TN that the city could expand the number of plows with GPS's. If it goes well tomorrow, he said, that could happen as soon as next week. As for making the data public in real time, "we wouldn't rule it out." In other cities, public access to real-time tracking data lets residents know when they can expect plows and buses.

subset: commoncrawl


text:
London, April 10 (Reuters): Robert Edwards, a British Nobel Prize-winning scientist who pioneered the development of "test-tube babies" conceived through in-vitro fertilisation (IVF), died today after a long illness, his university said. He was 87.
Edwards, who won the Nobel Prize for medicine in 2010, started his research in the 1950s, and the first so-called test-tube baby, Louise Brown, was born in 1978 as a result of his pioneering research. He founded the world's first IVF clinic in his home town of Cambridge, eastern England in 1980.
"It is with deep sadness that the family announces that Professor Sir Robert Edwards, Nobel Prize winner, scientist and co-pioneer of IVF, passed away peacefully in his sleep," Cambridge University said.


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Reginald Murphy Centre
Community venue in Kings Cross
Located in the heart of Kings Cross, the Reginald Murphy Community Centre is easy to access.
The centre hosts several educational courses, lunch meals, social activities and programs.
Community groups can also hire the venue for their own meetings and events.
We refurbished the centre in 2016 with a new office space, more flexible community areas and upgrades to the bathroom and kitchen.
Contacts19 Greenknowe Avenue
Potts Point NSW 201102 9265 email@example.com enquiries form
Venue hire information
Suitable for meetings, gentle exercise groups, rehearsals and small functions. The centre is located in the heart of Kings Cross.
It is available for hire Monday to Friday from 5pm to midnight and on weekends from 7am to midnight.
The room is 10 metres by 13.5 metres.
- dinner: 60 people
- cocktail party: 60 people
- theatre: 60 people.
Kitchen with:
- microwave
- hot water urn.
- 5 trestle tables (each seats 6 people)
- 40 chairs
- 6 lounge chairs
- ceiling fans
- piano and guitar.
Special considerations
- Noise needs to be kept to a minimum, residential area.
- Additional cleaning can be arranged.
- Some functions may require additional security.
- Alcohol is not permitted.
- Furniture to be put back exactly as found.
Wheelchair access is available from Greenknowe Avenue and the accessible toilet can be used by prior arrangement.
Transport and parking
- Kings Cross train station is within walking distance.
- Bus route 311 stops on Macleay Street, near Orwell Street.
- Bus routes 323, 324, 325, 326 and 327 stop on Bayswater Road, near Darlinghurst Road.
- Limited on-street parking.
- Ward Avenue parking station is nearby.
Standard room hire fees
- weekdays until 5pm: $42 per hour
- weekdays after 5pm, all day on weekends and on public holidays: $46 per hour
- day rate (Monday to Friday, 9am to 5pm only): $252 per day
- weekend full day rate, including public holidays (8am to midnight): $460 per day
- election surcharge: $1,140 per election
- security deposit (fully refundable): $300
- key deposit (fully refundable): $35
- community hire rate: 50% discount on standard hire rate.
Before hiring a City of Sydney community venue we ask that you read and understand the conditions of hire.
Last updated: Tuesday, 18 April 2017


text:
Fall 2013 edition of EY Navigator
Meet Mark Weinberger, our new Global Chairman and CEO
On July 1, 2013, EY proudly announced that Mark Weinberger will serve as our new Global Chairman and CEO. Mark, 51, has had a distinguished career with a track record of leadership both inside and outside EY. He previously served as the Global and Americas Head of Tax and on the Global and Americas Executive Committee. He has been a senior Advisory partner for many of EY's largest clients, and he also served on the Global Markets Executive Committee and Global Public Policy Committee. Mark was the Assistant Secretary of the U.S. Treasury (Tax Policy) under President George W. Bush and was appointed to the US Social Security Advisory Board by President William Clinton.
"It is a privilege to lead this great organization in these dynamic times, and I'm looking forward to tackling the challenges ahead," said Mark. "EY has a proud history that stretches back more than a century. Over that time we have forged our reputation based on quality, trust and integrity. We are building on our history and our reputation to create our future."
At EY, we make a promise to our people: whenever you join and however long you stay, the exceptional EY experience lasts a lifetime. We are proud of the relationships we have with our alumni, many of whom go on to serve in industry, government and even the not-for-profit sector.
We also regularly welcome back former team members who choose to rejoin EY — so regularly, in fact, that we have a name for them: EY boomerangs. These individuals return with valuable experience and perspectives that enrich our organization, which is exactly what new Global Chairman and CEO and four-time EY boomerang Mark Weinberger intends to do.


text:
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Although the administrators and moderators of this website will attempt to keep all objectionable comments off these pages, it is impossible for us to review all messages. All messages express the views of the poster, and neither Crash Media Group nor Crash.Net will be held responsible for the content of any message. We do not vouch for or warrant the accuracy, completeness or usefulness of any message, and are not responsible for the contents of any message. If you find a message objectionable, please contact us and inform us of the problem or use the [report] function next to the offending post. Any message that does not conform with the policy of this service can be edited or removed with immediate effect.
Tiago is cool.
Weather Relevant,attitude straight human couple county sale tree real fully pretty regular want date employer answer behind call generate whereas block award actual typical such outcome include case credit really dream stock sale equal love reason income launch serve college push clearly bone lovely permanent since when distinction organise suitable skill represent flight propose other scheme parent immediately create anyone citizen responsible let story meaning customer due night claim retain beyond ask human iron ignore jump floor pull constant upon describe appearance because body terms accept fly


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I want to get the CC Pro bundle but I don't know if it'll be available in my region. I don't have any CCs at all and the Pro looks much better. If it's not available, I'll have to buy the game and the controller separately.
Let's play some Monster Hunter 4 Ultimate! Let me know who you are before you add me.
3DS Friend Code: 4098-3796-9042
× steam


text:
Oregon Historical County Records Guide
Grant County Records Inventory
Mining Claim Records
Series documents actions filed with the county related to mineral interest claims. Types of actions include mineral rights and royalty assignments, mineral interest claims, lease releases, interest stipulations, corrections, bills of sale and conveyance assignments, and location notices. Information includes names of involved parties; action types and dates; and volume and page numbers. The series may also include copies of claim location notices giving descriptions and details of individual claims.
Since 1990 mining claims have been recorded in the clerk's Recorded Instruments (Clerk and Recorder Official Filings).
Records at the Oregon State Archives:
Miscellaneous [Mining Claims], 1862-1880 (1 reel of microfilm);
Rock Creek Mining District Record Book, 1864-1871 (1 volume).
Records at the Grant County Courthouse, Clerk's Office:
Affidavit of Posting Notices-Mining Claim, vol. 1, 1907-1940 (1 volume);
Direct and Indirect Index to Mining Claims [serves as claim register], vol. 1, n.d. (1 volume);
Dormant Mineral Interest Record, vol. 1, 1985 (1 volume);
Index to Mining Records Canyon Creek and Marysville [includes water rights], 1862-1863 (1 volume);
Mining Claim Record [includes water rights-with index], vol. C, 1864-1879 (1 volume);
Mining Claims [Records-with index], 2011-present (3 binders);
Mining Record Canyon Creek and Marysville [includes water rights], 1862-1863 (1 volume);
Mining Record [title varies-with index], vol. D-Z, 27-84, 1879-2005 (87 volumes);
Patented Mining Claims [Record-with index], 1880-1907 (1 volume);
Record [Mine Claim Notices], vol. B, 1878-1900 (1 volume);
Record Mining Claims Conveyance [with index], vol. A-B, 1864-1881 (2 volumes);
Record of Affidavits of Posting Notices [includes mining claims-with index], vol. 2, 1928-1968 (1 volume);
Record of Mining Claims & Notices Granite Dist. [District], 1877-1880 (1 volume);
Records Mining Claims Conveyance [with index], vol. C, 1882-1901 (1 volume);
Request for Notice to Mining Claimants [with index], vol. 1, 1956-1960 (1 volume).
Records at the Grant County Courthouse, Clerk's Office, Side Room:
[Mining Record-includes river claims, bills of sale, bank claims, gulch claims, and water rights], 1862-1865 (1 binder);
Misc. Information Letters, Land Records, Mining Claim [includes deeds, land grants, mining claims, and related records], 1869-1893 (1 binder).
Records at the Grant County Courthouse, Clerk's Office, Break Room:
Dormant Mineral Interests [Record], vol. 1, 1985 (.50 inch of aperture cards);
Miscellaneous BLM Surveys & Volumes [Mineral Survey Records-General Land Office/Bureau of Land Management], ca.1872-ca.1952 (3 inches of microfiche);
Mines Book [Claims], vol. 41-75, 1971-1990 (24 inches of aperture cards).
Records at the Grant County Courthouse, Assessor's Office, Surveyor's
Storage Room:
[General Land Office/ Bureau of Land Management Survey Records-includes some mineral surveys], ca.1865-ca.1997 (5 inches of microfilm).
Records at the Grant County Courthouse, Basement Vault:
Mines [Mining Record-with index], vol. 53-75, 1980-1990 (13 inches aperture cards);
Mining [Mine Location Notice Records-includes related documents], ca.1889-ca.1919 (7 binders);
Record Certificates Issued to Co-owners [mining claim sales], vol. 1, 1904-1943 (1 volume);
Record Notices & Affidavits Co-owners [mining claim sales], vol. 1, 1904-1943 (1 volume).
Records at a Related Web Site:
Mining Record Canyon Creek and Marysville [includes water rights-with index], 1862-1863 (FamilySearch.org);
Online Land Records [includes various federal land survey records related to Oregon such as survey plats and field notes, mineral surveys, and historical indices], ca.1850-present (Bureau of Land Management).


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Hey gang today enjoy the hunt , enjoy the meal but most of all enjoy the time with family and friends.
Moderators: Tealer, Indaswamp, Dep6, Preacher1011, lostpup, La. Hunter, steve-o
cootlover wrote:I have hunted the last six day's.Taking today off to spend with the family. Happy Thanksgiving and let's remember what's today about NOT WHAT Walmart think's it's about
Jarbo03 wrote:Those two are nothing but life support systems for vaginas
Users browsing this forum: No registered users and 6 guests


text:
All Android applications categories
Alligator Wallpapers
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★Save images as wallpaper.
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An alligator is a crocodilian in the genus Alligator of the family Alligatoridae. There are two living alligator species: the American alligator (Alligator mississippiensis) and the Chinese alligator (Alligator sinensis). In addition, several extinct species of alligator are known from fossil remains. Alligators first appeared during the Oligocene epoch about 37 million years ago.
The name alligator is an anglicized form of el lagarto, the Spanish term for "lizard", which early Spanish explorers and settlers in Florida called the alligator.
Copyright notice: All images copyright their respective owners.
Legal notice: We believe our images fall under the fair use doctrine as they are reduced size and excerpted for informational purposes. However, if you would like to request removal of an image from our collection for copyright reasons, feel free to contact us at and we'll be happy to oblige.
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text:
I start in a week and a half but being in high school gives me time to work on my mando
I start in a week and a half but being in high school gives me time to work on my mando
I think it's okay as it is, the helmet doesn't have to be exactly the same as boba/jango's
I'm making mine similar to the TOR version (BH)
I think I want it flatter. My bucket's kinda got this bubble head look to it. LoL... I start school tomorrow and today's my mom's birthday so I doubt I'll get anything done for a while. But I aim to finish it this year.
Man I wish I was homeschooled. I hated high school so I dropped out when I was 16
But college is soooo much better, I enjoy going to school now...start back tomorrow on my 2nd year of a Game design program.....sorry for the off topic.
Ordeyn your armor and helmet are looking very good so far, just make sure you get it done by Halloween so you can show it off!
VERY nice work! I sat down and read thru the entire thread today, because I will be building THREE sets of female armor out of trashcans in the near future. Ok, near enough that I bought two trashcans *today* as a start. Fortunately, two of the females are quite small - 9 and 4 - so I won't need as much trashcan material *&* won't need to dish the breastplates. Excellent thread and very gorgeous work.
Oh, and we don't start our homeschooling back up until Sept. I think I'll put armor-making on the cirriculum this year and have the two older kids work on their own armor and have the verd'ika (that right? littlest one?) "help" with hers.
Yeah. Homeschooling is awesome, for those it works for.
I was homeschooled from 2nd grade on through High School (finished at 12), and I loved it. I just ran through everything really fast, and didn't have to wait for everybody else to finish. My sister hated it though, and wound up going to private school from Jr. High on.
Works for some, not for others, I suppose.
And Doc, verd'ika means "little soldier/warrior". Ad'ika would be "little son/daugher". You're the coolest buir ever. I wish my schooling had included Mando making.
Ad'ika also means little one... as in not your child but someone elses, or someone who is small in stature.
Very true, Kal. Thanks. My Mando'a is a little rusty
no prob happy to help out
Yea my high school dayz were terrible, c's and d's all the way, but when I went to college, a's and b's, I guess it's because I got to CHOOSE WHAT TO TAKE, (mostly.. I still need a few classes for my Degree).
hmm... sounds familiar, except I had a lil better results in HS, just not good enough to get any scholarships . however... did just fine in college. In fact... have to start my masters soon.
I do however have a BS in BS Actually I am working on my BSN, then later will go for my MSN, but higher education is worth it.
Amen! lol, same here... i can't go to the range without my 4 yr old wanting to tag along. It's very important to teach kids the value of safety at an early age, it prevents stupid accidents like the ones we see increasingly happening with adults who were never exposed to good safety training. I was never a boy scout, but I know that they, as well as 4-H, most "Sherriff's camps" and many state LE sponsored summer camps such as Trooper Island Camp in Kentucky do offer such opportunities for kids... I know because I worked at both a 4-H and Trooper Island Camp once upon a time as one of the riflery instructors. Kudos to you ner vod for teaching your kids the important things in life, and not focusing them in on videogames and TV!
Kal Waco
Hey, guys, sorry Ive been away for so long! School and soccer are crazy. I'm playing for a school team and a club team at the same time. Homework, practices, and games take up most of my time. I barely squeezed this message in, LoL. But I'll get that backplate attached eventually! I'll keep you posted on any progress I make best I can.
Glad to see your still alive!!! isnt the life of a soccer player great? I miss doing what you are describing... Now I only play in a few pick-up games everynow and then. It is so hard to find a good team when you are here in AZ and everyone plays mexico style soccer, and you are playing European style...
GO SOCCER soccers a great game eh
I'll convert you all to West Brom supporters yet, who needs your Man United and Chelseas? Just because they win things all the time? Nah? You want a local British club for local people like, er, those in the US, and not hunt the glory! West Brom is just that... [/soapbox moment]
What is this "Soccer" you speak of? I know of 'football'..
I never understood why us Yanks call Football Soccer? I mean , you use your feet for Soccer and your hands for Football?!?!
Edit, if you want me to take that last pic down I will, just lemme know
Oh question, which of these look more painful
Last edited by adonian; Aug 28, 2009 at 5:40 PM.
ok... time for a quick bump up post! Ord'ika, any progress?
Yeah, what's happenin?


text:
Dan Bauch, Kyle Brightwell, Matthew McKay, and Craig McNutt, Directors
Open to advanced percussion players.
Auditions held in September. To schedule a September audition, contact the Preparatory School office after August 1st at (617) 585-1160 or at firstname.lastname@example.com.
For more information, click here.
Rehearsals – Saturday, 1:00 – 2:30 PM


text:
Building Community University Engagement: A Program Theory Approach
Delaforce, Wayne H. (2004) Building Community University Engagement: A Program Theory Approach. In Social Change in the 21st Century Conference, 29th October, QUT, Brisbane.
|PDF (131kB)
The Queensland University of Technology (QUT), like other Australian Universities, is seeking to advance collaboration across external boundaries through "community engagement" in response to policies at National and State levels that invoke rationales such as resource efficiency and coherence in regional educational delivery. As a result, an alliance of regional education sector providers including QUT established the Northern Corridor Education Precinct (NCEP) in 2001. The alliance recognised that no individual provider, organisation or community can fully deliver a complete learning experience in isolation. In an environment of changing education landscape the NCEP has reaffirmed that it exists to develop and provide cross-sectoral leadership by introducing and maximising a co-ordinated approach to learning for our community. While these goals have been formulated as a means of operationalising regional level initiatives, QUT's articulated organisational strategic requirement is to identify and operationalise 'best practice' standards. Meaning a clearer framework and model are needed to articulate the logic analysis processes and desired outcomes of collaboration. This is a complex task with university engagement policy articulated at three levels of governance national, state and specific university level. Thus it is necessary to examine the policy logic at each of these levels to identify the relationships assumed to be at stake in bringing about community engagement. In order to do this the paper first begin to explore the concept of program theory as a level of analysis suited to identifying the logic of policies and their implementation in programs. Secondly, the paper examines the current national and state education sector policies developing a framework of the articulated policy, as desired outcomes and mechanisms. The QUT strategic vision and logic of collaboration, QUT Blueprint 2004 is also examined from an organisational and systemic context. As a result of the examination, this paper outlines the articulated logic underpinning the three levels of policy informing community engagement strategies and identifies the relationships and the emerging articulated language and rhetoric. Thirdly, a brief examination of research around education sector engagement identifies a conceptual gap in the mechanisms and application for such initiatives. It is suggested that in the context of the development of learning regions in a knowledge economy, universities have a leadership role at the level of ideas and values and that, 'boundary spanning' is required as a means of achieving the collaborative relationships identified in policy. The paper argues that in order to undertake regional, collaborative, cross-sectoral education and community engagement a conceptual framework that identifies the processes and issues involved is needed. The proposal is raised and will be developed further in subsequent papers that 'boundary spanning' and sectoral, community interface occur at a symbolic dimension and the work of Benedict Anderson on "Imagined Communities" informs this process and allows a working framework to emerge.
This framework will reflect the work in the NCEP over the past three years as vehicles to create in the words of Donald McNeill (2001) "Spaces of Engagement" in which community engagement can occur. The paper proposes that this approach sheds new light on the processes of organisational boundary spanning that need to occur if universities are to engage with their constituent communities. This represents one way to fill the identified process gap and transcend the strategic operational divide.
Impact and interest:
Citation counts are sourced monthly from Scopus and Web of Science® citation databases.
These databases contain citations from different subsets of available publications and different time periods and thus the citation count from each is usually different. Some works are not in either database and no count is displayed. Scopus includes citations from articles published in 1996 onwards, and Web of Science® generally from 1980 onwards.
Citations counts from the Google Scholar™ indexing service can be viewed at the linked Google Scholar™ search.
Full-text downloads:
Full-text downloads displays the total number of times this work's files (e.g., a PDF) have been downloaded from QUT ePrints as well as the number of downloads in the previous 365 days. The count includes downloads for all files if a work has more than one.
|ID Code:
|Item Type:
|Conference Paper
|Community Engagement, Programme Theory, Collaboration, Higher Education Policy Framework
|Current > Research Centres > Centre for Social Change Research
Past > QUT Faculties & Divisions > QUT Carseldine - Humanities & Human Services
|Copyright Owner:
|Copyright 2004 Wayne H. Delaforce
|Deposited On:
|28 Jun 2005 00:00
|Last Modified:
|09 Jun 2010 12:26
Export: EndNote | Dublin Core | BibTeX
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text:
A Phase I Study of BMS-690514 in Patients With Advanced or Metastatic Solid Tumors
This study has been completed.
Bristol-Myers Squibb
Information provided by:
Bristol-Myers Squibb
ClinicalTrials.gov Identifier:
First received: May 19, 2006
Last updated: January 24, 2011
Last verified: August 2009
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
No Study Results Posted on ClinicalTrials.gov for this Study
|Study Status:
|This study has been completed.
|Study Completion Date:
|July 2009
|Primary Completion Date:
|July 2009 (Final data collection date for primary outcome measure)
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Soria JC, Baselga J, Hanna N, Laurie SA, Bahleda R, Felip E, Calvo E, Armand JP, Shepherd FA, Harbison CT, Berman D, Park JS, Zhang S, Vakkalagadda B, Kurland JF, Pathak AK, Herbst RS. Phase I-IIa study of BMS-690514, an EGFR, HER-2 and -4 and VEGFR-1 to -3 oral tyrosine kinase inhibitor, in patients with advanced or metastatic solid tumours. Eur J Cancer. 2013 May;49(8):1815-24. doi: 10.1016/j.ejca.2013.02.012. Epub 2013 Mar 13.


text:
Press Releases
CONTACT: Charles Schuler
Associate Deputy Airport Director
Communications and Marketing
(650) 821- 5031
San Francisco International Airport Welcomes Lufthansa's A-380
Super Jumbo Jet Begins Regular Service Between SFO and Frankfurt
SAN FRANCISCO —Another milestone in San Francisco International Airport's history was marked today as Lufthansa becomes the first carrier with regularly scheduled A-380 service between Frankfurt and SFO. The Airbus A-380 is the world's largest passenger aircraft and is configured to accommodate 526 passengers, with eight seats in First Class, 98 seats in Business Class and 420 in Economy Class.
Officials on hand to welcome the inaugural flight included Supervisor David Chiu, President of the Board of Supervisors of the City and County of San Francisco, Airport Director John L. Martin, Joe D'Alessandro, President and CEO of the San Francisco Travel Association, Richard Carcaillet, Airbus' Director of Product Marketing for the A-380, and Carsten Spohr, CEO Lufthansa Passenger Airlines. Also, as part of the welcoming celebration, the Airport and Lufthansa co-hosted a " Plane Spotting" party at Millbrae's Bayshore Park.
"San Francisco's International Terminal was designed and built to specifically accommodate aircraft such as the A-380," said Airport Director John L. Martin. "We are extremely pleased that Lufthansa will be the first airline to have regularly scheduled A-380 service to San Francisco and we warmly welcome their passengers as they arrive in North America's finest airport."
Lufthansa's flight 454 is scheduled to depart Frankfurt at 9:33 a.m. and arrive at SFO at 11:55 a.m. The return flight, LH 455, is scheduled to depart SFO at 2:20 p.m. and then arrive in Frankfurt at 10:05 a.m. the following day.
About San Francisco International Airport
San Francisco International Airport (SFO) offers non-stop links with more than 31 international points on 29 international carriers. The Bay Area's largest airport connects non-stop with more than 69 cities in the U.S. on 20 domestic airlines. For up-to-the-minute departure and arrival information, airport maps and details on shopping, dining, cultural exhibitions, ground transportation and more, visit www.flysfo.com. SFO was voted "North America's Best Airport" in 2010 by passengers for its modern and efficient facilities and its multi-modal transportation systems. .


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Many of you are hoppin' mad about D.C. United's deal with Comcast SportsNet, one that provides live coverage of just 16 matches and leaves as many as nine games absent from the TV schedule. Your anger is justified. In this day and age, everything is on TV. Heck, cameras are focused on Brandi Chastain and Kareem Abdul-Jabbar diving into a pool. (What, Luis Suarez wasn't available?)
CSN has essentially made a summer commitment: 14 consecutive matches between May 8 and Aug. 3, with an additional game in both mid-August and mid-September. The channel has the option of picking up more matches — at the moment, five of the last 10 have no TV assignments — but that decision will hinge on summer ratings, available time slots and financial considerations. United will undoubtedly press CSN to add games, but in the end, it's the channel's call.
Production costs start at $35,000 per game, and as part of the contract, CSN is covering all such expenses. (Production costs are lower for away games when talent is not on site.) Could United pay for additional games? It could — but probably won't. Why? It sets a precedent for "buying" air time and paying its own way, when, in the long run, the club wants to position itself as a entity worthy of a channel's interests — and its financial commitment. This approach, however, is no consolation to the average spectator, who simply wants to watch a potentially important late-season match and doesn't care about business posturing.
If CSN doesn't want to show those games, perhaps an over-the-air channel (Channel 20 or 50) would want them? Well, maybe. But they are not going to pay production costs when they can fill time slots with their network shows at no additional expense. And let's be frank: United matches do not draw enough viewers for a station to alter its schedule and spend large sums when it already offers original programming.
What should be noted here is United appears to have forged a good financial deal with CSN. While almost all other MLS clubs offer more local programming than United, many are also paying entire production bills. CSN is picking up the tab in Washington. Which raises the question: What is United doing with those savings? After all, the club did not spend an enormous amount on player acquisitions this winter. I don't have a definitive answer, but money saved on TV could provide the resources for a major signing during the summer transfer window. Or more likely, it's a matter of thrift: Until United opens a new stadium, revenue streams are limited and the club is trying to slow the bleeding.
United is also saving money by not sending announcers Dave Johnson and John Harkes to away matches. Calling a game off monitors in the CSN studio in Bethesda is minor league, but again, financial considerations won out. (The announcers work for the team, not the network.)
United officials say they had three credible offers for a local TV partner. They wouldn't name the other two, but my hunch is one was Verizon FiOS, which has limited availability. So why did they sign with CSN? Three key factors were in play: time slots, reach and money.
*Without baseball, CSN has abundant time to fill in the summer. Mid-Atlantic Sports Network, the region's other sports outlet, carries both the Washington Nationals and Baltimore Orioles almost every day from April to October.
*CSN is available on myriad cable systems and is synonymous with Washington sports coverage — for both game coverage and studio production. Being on CSN means you are part of the regional sports landscape.
*CSN agreed to pay production costs.
United's choice was clear; it was just a matter of working out the best possible deal.
The pact is for three years, which is good and bad. On the bright side, we won't have to go through this anxious waiting period the next two springs and United has a long-term commitment that doesn't saddle the club with production expenses. On the gloomy side, the terms are the same: 16 games per year, with CSN's option to add more.
What United is trying to do is line itself up for future growth: Now that the club isn't spending money on TV — in recent years, the club split production costs with CSN — United believes the next step (in at least three years) is to begin making money on TV. That, however, would require sustaining a quality on-field product (winning = public interest = ratings = rights' fees) and reaching a stadium deal.
Without a new venue, United will continue to tread water in a highly competitive sports market (Redskins, Ravens, Wizards, Capitals, Nationals, Orioles, University of Maryland football and basketball, Georgetown basketball and more). Remaining at RFK, which has seen better days and is too large for MLS purposes, while continuing to lose a ton of money also feeds the general public's perception that United may someday skip town for greener pastures. A new stadium would bring permanency and a destination for casual fans. For all of its wonderful history and spirit, RFK is not on most people's weekend planner. While in a perfect world, everyone would turn out solely for the 90 minutes of competition, the stadium experience remains a significant selling point in American sports business.
Another issue on the TV front is the rapid changes in our viewing habits. While United's game tonight at Kansas City and next weekend against New York are not on a standard channel in the Washington area, they are available on MLS's pay packages: Direct Kick (cable and satellite) and MLS Live (online and mobile devices).
Increasingly, people are turning to non-TV alternatives for sports and entertainment video. Hardcore soccer supporters have been going this route for years. But if United — and soccer, in general — wants to grow, it needs to appeal to a broader audience. The way to do that is by arranging for more games on standard TV, not fewer.


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- Joined 9/2007
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When did garlic scapes start costing more than asparagus?
- Joined 2/2007
- Location: Central Kentucky---where the bluegrass meets the mountains
- Posts: 6453, Reviews: 29
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Garlic scapes began to become an in ingredient four or five years ago, and in some places sell for as much as $15/pound. So, if you're paying two bucks for a six ounce packet you're ahead of the game. That would only be four dollars for the modern 12-ounce "pound."
- Joined 2/2007
- Location: Central Kentucky---where the bluegrass meets the mountains
- Posts: 6453, Reviews: 29
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- Joined 5/2006
- Location: CANTON GEORGIA was Palm Beach Florida,New York City
- Posts: 3365
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- Joined 7/2008
- Location: Central PA
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The fundamental problem for the smaller farmers is that they have three different kinds of products: the expensive gourmet ones that only wealthy people and sometimes chefs buy, the inexpensive ones that everyone wants in vast quantity, and the ones that ought to be products but nobody seems to want.
Type A example: funny-colored beets. Chefs love them, fancy gourmet types love them, locals often won't touch them, or want to pay the same as for regular beets per pound. If you're going to grow them at all, you have to keep the quantities down and the prices up or you get hosed.
Type B example: tomatoes. The danger is that you can easily get undercut by the next farmer over, everyone buys his first because they're 5 cents cheaper per pound, and now you've got 10 pounds of tomato seconds that you can't sell for almost anything. So although these are your mainstays, they're very volatile and research-intensive.
Type C example: unusual types of onions. An onion is an onion is an onion, says almost every purchaser, unless it's a Vidalia or something. You might get a hair more if you have an heirloom variety, but you won't move much product. The stuff just hasn't become a hot ingredient yet, so nobody's interested.
So here I am, the organic farmer, and suddenly garlic scapes are the hot ingredient. Can you blame me for shifting them from Type C to Type A? You have no idea how close to the red these guys live. The prices you cite strike me as very high, but I'm thinking of the northern Vermont summer market, which is quite different (like, less expensive because less hip because hard to get to from New York). Nevertheless, any organic farmer worth his manure will seize on any opportunity to jack a price and maybe (cross fingers) make a profit this year. Until, of course, the freak rainstorm wipes out this week's greens....
So, I am a HUGE supporter of local organic produce, but, I think the real problem for farmers is that having a small organic farm with a very diverse crop is not a business model that works -I'm not saying they all should plow their land and plant one crop, that is terrible for the land, but being a little less diverse, finding a middle ground between commercial and small organic farms (closer to the small side) and focusing on 4 or 5 heirloom products might be a more profitable? I don't know? I'm not a
farmer. -so I probably don't know what I'm talking about. But I've seen too many idealistic go down in flames, because they forgot they were running a business.
- Joined 5/2011
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Buoana boy, I am an organic gardener and I think there is something you should know about diversity in crops.
When a gardener plants his field, let say full of peppers and tomatoes, potatoes in the fall and carrots, in the spring kale, swiss chard and just continues to use those staple crops year after year, they are ignoring a very important concept and practice when it comes to small scale farming; it's called crop rotation. Many organic gardeners impress this idea about crop rotation and it's main purpose is to prevent disease. If you come upon the mass disease occurrances and it gets on everything, then your crop is ruined. Chemicals can prevent it, but there goes your organic out the window.
A way to combat the natural occurrance of diseases from multiple years of planting the same plant in the same spot is plant diversity. If you keep switching your crop and grow lots of vegetables, then the disease bacterias will fade away preventing the local organic gardener from using chemicals. Hope that helps you understand the reasons why some have lots of diversity.
- Joined 2/2007
- Location: Central Kentucky---where the bluegrass meets the mountains
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OG, perhaps you didn't notice, but this thread is two years old, and I don't recall seeing any recent posts from buoana boy in some time. So don't be surprised if there's no response from him.
That aside, your comments re: rotation seem grossly oversimplified. They certainly overstate the case.
In theory, crop rotation is practiced for two reasons: to prevent depletion of nutrients, and to deter pests and disease. The first is totally in disrepute. Whether you are organic or use conventional chemical farming, it doesn't truly apply---and likely never did. Either way you are replacing nutrients. The only difference between you and a synthetic chemical proponent is that you are creating healthy soil and the other guy isn't. But both of you are replacing depleted nutrients on an on-going basis.
Pest and disease prevention only makes sense if 1. You have an incredible amount of land (not true for the typical diverse organic grower), or can so arrange your crops that neither the original species nor any relative is within migration distance of an infection---difficult with soil-borne organisims, nearly impossible with air-borne ones.
Let's say you had a problem with tomatoes in one area, and have enough space to safely move them out of the way (which can mean not planting them downwind, as well as planting them far away). The list of things you cannot plant in the original area (or even close to it) includes peppers, eggplant, potatoes, and, to stretch a point, tobacco. Disease bacteria do not just fade away. Self-sanitation can take as much as three or four years; three or four years in which you cannot return the original or its relatives to that location. So the question becomes, do you have enough land to grow them far enough away? Or do you drop them altogether? And, if the latter, what do you replace them with that is marketable?
On the other hand, if you've never had a significant infection, there's no reason not to grow tomatoes in the same ground, year after year.
I'm not suggesting that crop rotation is totally ineffective. But it's not the panacea many growers have been led to believe. And the mechanics of it can drive you to drink.
Edited by KYHeirloomer - 5/22/11 at 6:12pm
- Joined 11/2008
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So, I fell in love with duck hunting several years ago, but for reasons I won't go into, I now have no places to go hunt, no calls, and virtually no experience. The only things I do have, are my shotgun, and a dozen mallard decoys. Now, I don't have much money at the moment, so getting more decoys is pretty much out of the picture, I could maybe afford 1 decoy by hunting season, and I wish I was exaggerating. Also, I'm painfully aware that with my lack of experience, calling is probably going to do more to scare the birds away then bring them in this season. Anyway, on to what I'm asking for, though any general advice is more than welcome.
I live in Potsdam NY, and I'm looking for a place within 30 minutes if possible, but definitely no further than an hour. I do have a boat I could use if I need it, but I'd prefer somewhere shallow enough to retrieve with waders. I have no dog, btw.
I would like a call or two this season, if for no other reason than to get some experience calling and seeing the bird's reactions(like I said, I don't expect to have any success calling this season, but the sooner I make my mistakes the sooner I can learn from them). So, considering that my decoys are for mallards, I imagine a mallard decoy would be best, but I don't know what brand or type of call to look for. Also, in the past I've had widgeon, blacks, and wood ducks come into mallard decoys, so I would like a call(if possible) that will have some effect on these birds, even if it's not ideal for them.
That said, any general advice would also be greatly appreciated.


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PALS - Pediatric Advanced Life Support Provider for Healthcare Providers at CHI SERMC
CHI Health St. Elizabeth Regional Medical Center
Wednesday, April 5, 2017 from 8:30 AM to 4:00 PM (CDT)
Who's Going
San Francisco, California
London, United Kingdom
Florence, Italy
Event Details
THIS IS A TWO DAY COURSE Dates listed are start dates. This is 16 Hours Total Day 1 (8 hours and Day 2 8 Hours)
The AHA's PALS Course has been updated to reflect new science in the 2015 AHA Guidelines Update for CPR and ECC. This classroom, Instructor-led course uses a series of videos and simulated pediatric emergencies to reinforce the important concepts of a systematic approach to pediatric assessment, basic life support, PALS treatment algorithms, effective resuscitation, and team dynamics. The goal of the PALS Course is to improve the quality of care provided to seriously ill or injured children, resulting in improved outcomes.
This course if for first-time students that have a current BLS certification or those who have let their previous PALS card expire.
Completion results in a certification card that is valid for two years. All participants are required to review the student manual prior to coming to class.
Location: CHI Health St. Elizabeth Hospital
***You will recieve a followup email with Course Location, Pre Course Info & an Invoice once you are signed up.
Cost: Our cost is $250.00. Cash or Check (made out to "Code Blue")
If you have any questions please call Ashley at 402.980.3197 or email: email@example.com Thank You!
When & Where
CHI Health St. Elizabeth
555 S 70th St
Lincoln ,
Wednesday, April 5, 2017 from 8:30 AM to 4:00 PM (CDT)
Add to my calendar
CHI Health St. Elizabeth Regional Medical Center
Questions please call Ashley 402-980.3197 or email@example.com


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Typically a recycling program fails because of apathetic citizens. But just the opposite has been the problem of Missoula's glass-recycling program.
"It has been a victim of its own success," says MontPIRG campus organizer Chris Zeech. "There's just way too much supply and not enough demand."
It seems the Missoula City/BFI glass-recycling program was doomed to fail from the beginning. Last year, both the Missoula City Council and Mayor Mike Kadas signed a pledge committing themselves to the recycling effort.
However, the commitment couldn't change the fact that the only use for collected glass was as fill in roadbed cushion. Now the city's Public Works Department has more glass fill than its needs, says Zeech.
Problems surfaced when environmentally-minded people from all over the county flocked to the recycling centers with bags and boxes full of glass. Because the cushion in the roadbeds is made up of only 10 percent glass fill, and there are only so many roads being laid, the city quickly found itself with a glass surplus.
"I would have had to order 80 years worth of cushion to use all the glass we have," says city street Superintendent Brian Hensel.
When the city stopped needing glass, the centers had nothing to do with the recyclables and had to stop accepting them.
Even if the demand for glass fill didn't dry up, there would be other obstacles to overcome. The glass is typically crushed into three-eighths of an inch-sized pieces. But sometimes longer, thinner shards pass through the crushers' screens and these shards pose a safety risk. Not only are they dangerous for crews working on the roads, but they can be a hazard to pedestrians, says Hensel.
"Can you imagine laying these out on the streets?" he asks. "Sometimes they can't pave these streets right away. I don't want my kid walking out on that."
All these problems have grabbed the attention of Rep. Tom Facey (D–Missoula), and members of the Montana Public Interest Research Group (MontPIRG). After examining the issue, they have come to the conclusion that this problem is far bigger than just Missoula.
"What has been going on in Missoula is what has been going on across the state," says Zeech of the collected glass surplus. "So it needs to be the whole state, not just towns, who find the solution."
Facey and MontPIRG plan to make the uses for glass more desirable to both the state and private sector. Facey hopes the state will purchase a few small, portable crushers that cost around $50,000 apiece. These units are capable of pulverizing glass so fine and so clean that it's safe enough for use in children's sandboxes. In this form, it could be used not only in roadbeds but in concrete and asphalt, says Facey.
"The idea behind this is to establish a market for crushed glass in Montana," he says.
One seemingly obvious solution would be passing legislation requiring all new state roadbeds to be made up of 10 percent glass fill. The drawback to this plan is that Montanans don't use enough glass to provide that much fill, which means the state would be stuck importing glass—the cost of which would make the project impracticable, says Facey.
Another solution, which also seems palpable, is recycling old bottles into new ones. This isn't as simple as it sounds. Because Montana doesn't have a bottling plant, the glass must be shipped out of state, probably to Seattle or Denver, to be recycled and is too expensive. Recycling companies gave up on this years ago because the price of glass became too depressed to turn a profit, according to Cindy Atkinson, marketing and sales director for Rocky Mountain Recycling.
While the politicians, activists and companies try to find an agreeable solution, Tom Ernst, the owner of Missoula Valley Recycling, urges people to keep pressuring decision makers. In a newsletter sent to his customers Ernst wrote:
"Ask your favorite county commissioner, or city council member to get back to the table, and solve this issue. One road construction supervisor related, 'If the city really wanted to get rid of their glass, you wouldn't have a problem.'"
Because it may be months until the area sees glass recycling return to Missoula, people dedicated to the effort need to come up with their own solutions. Something as simple as not buying glass is a great place to start, says Ernst.
After Ernst realized that about 85 percent of the glass his company picks up are beer bottles and the amount of beer cans they pick up is increasing, something dawned on him.
"We don't have to throw out our glass or buy PBR in cans," he says. "You can't always change the system, but you can change habits."
In fact, Missoula Valley Recycling is purchasing half-gallon growlers, which will be delivered to the company's customers free of charge. On the back of the bottles will be a list of local breweries and taverns where the containers can be filled. Each time a person opts to fill up one of these growlers, 5.3 beer bottles will be eliminated from the waste stream headed toward the Missoula landfill, says Ernst.
While glass only makes up about 6 percent of Missoula's landfill, saving landfill space for the toxic, non-inert substances is one of the main reasons to recycle or reuse glass, says Ernst.
One final alternative is offered by the Good Food Store. The store accepts glass jars with openings of two inches or wider, says lead cashier Chris Elliott. They can be dropped off clean any day of the week.


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About a year ago I stated that the ViewSonic VP211b was the best desktop screen I had ever seen, but now ViewSonic is trying to trump the VP211b with the VP231wb. The VP211b was 21.3in screen with a native resolution of 1,600 x 1,200 and a stand that was head and shoulders above the competition. The VP231wb is a 23in screen with a massive native resolution of 1,920 x 1,200 and the same VP series stand. So, on paper at least, it looks like the VP231wb is set to steal the crown from the VP211b.
As the b at the end of the model name suggests, the VP231wb is finished in matt black. The black bezel means that this screen can only receive a TCO '99 rating as opposed to the newer TCO '03 which insists on a light-coloured bezel. Personally though, I prefer black bezels and don't put a huge amount of stock in the TCO standards anymore.
Despite the screen's impressive dimensions, the bezel has still been kept very narrow, in keeping with the rest of the VP range. ViewSonic has also kept the branding and labelling on the bezel very subtle, so as not to spoil the clean lines.
Below the screen, set into the front fascia, you'll find the usual five buttons that adorn all ViewSonic monitors. On the far right there's the power button with an indicator light next to it – this glows green when the screen is active and yellow when it's in standby. As usual there are up and down arrow buttons, and two buttons marked 1 and 2, which equate to Menu and Select.
The OSD is pretty comprehensive and you'll find a decent amount of adjustments to get your image just about perfect. Of course, if you're connecting the VP231wb to your computer via DVI, you won't need to make many adjustments – as long as you have a graphics card and driver that supports reduced blanking, you should be able to manage the native 1,920 x 1,200 resolution over a single link DVI. If you do decide to connect up the VP231wb via an analogue D-SUB, you'll still get a good image, and the extensive colour adjustments will help you get the image just right. That said, the auto adjust option does a very good job, and saves you a lot of time and effort.
Because the VP231wb shares the same stand as the rest of the VP range, it benefits from some great features like dampened height adjustment – this makes it easy to get the screen to the right height with minimum effort. You can also pan the display from side to side easily, as well as tilt it forwards and backwards. The screen is mounted on a central telescopic column with two angled feet that make the whole device very stable, but without resulting in an overly large footprint. Down the back of the central column, there are three cable tidies which help to keep those clean lines unsullied protruding cables.
One feature that is missing is the ability to pivot the screen, which is a real shame. All of the other monitors in the VP range will allow you to pivot the screen into a portrait format, allowing you to view far more of a long document than you could in landscape mode. ViewSonic said that the portrait mode was disabled because the screen would hit the desk when being twisted, and this is probably true. However, the lack of pivot function is a limitation of the standard VP stand, since it doesn't rise high enough to facilitate pivot functionality with a screen this size. The stand on the hp 2335 however, allows for a couple more inches of vertical movement, and thus gives you enough room to pivot a large 23in screen.
At the rear you'll find both DVI and D-SUB ports, a power socket and a hard power switch. Unfortunately, the power supply isn't integrated into the screen or base, so you have to accommodate a very bulky external power brick, although the flip side is that you have a very slim power cable routing to the screen itself. Also at the rear is a USB 2.0 hub with one upstream and four downstream ports. This is a pretty useful addition if you keep your PC on the floor, especially since it operates at the faster USB 2.0 standard rather than the older USB 1.1.


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Miniature Flirts - Smile Photo Props - Set of 2
Product Info
This set includes two props: the miniature Flirt (puckered smiles) in both red and pink. A drawstring cotton bag is included.
• Molded in hard plastic - they're durable and sanitary!
• Great to use for kids portraits and parties
• Can be used as cupcake toppers
• Large quantities are available
Dimensions: Approx. 1.5" wide, each on a 4" stick.
Find other miniature sets here:
Plastic • Durable • Sanitary • 3D • Handmade in America
Shipping information, FAQs and shop policies are available here:


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I have a client who has worn pink-and-white acrylic for years, but all of a sudden all her nails have begun lifting from the nail bed. It's a very small amount, only on the right side of the nails. It almost looks fungal. She has not changed anything, diet, medication, etc., that we can think of. Do have any ideas what this could be?
You are describing onycholysis, which is when the nail separates from the underlying bed. In this scenario, air under the lifted nail appears as a white or yellow discoloration. You will observe the normal white tip of the nail begin to track toward the cuticle. This may occur for a number of reasons. New onset onycholysis can indicate that something is going on with the thyroid. Your client should be referred to her dermatologist or primary care physician for laboratory testing. Another scenario and the more likely cause is that your client may have developed an allergy to one of the chemicals in the acrylic causing the nails to separate. Even if the client has been wearing acrylics for years an allergy can still develop. The other possibility is that the nails are being cleaned with an implement too vigorously. This can cause separation of the nail from the underlying bed. Regardless of the scenario, your client should be seen by a dermatologist so that she can be treated in a prompt manner. Onycholysis is relatively easy to treat if caught early, but if it persists it can cause permanent separation of the nail from the underlying nail bed.
— Dana Stern, M.D. is a board-certified dermatologist specializing in nails. She works in private practice in New York City.
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ACM TechNews is published every week on Monday, Wednesday, and Friday.
To send comments, please write to email@example.com.
India's fast-growing software industry is worried that political trends in the United States will mean a pullback from offshore outsourcing from that country. India's software industry trade group, Nasscom, held a meeting in Bombay this week with executives from American firms, but discussion on new legislation in New Jersey was cut short by one of Nasscom's vice chairman out of fear it would make the issue even larger in the public eye. American delegates said the issue was best played down because of the strong emotions evoked. Like manufacturing jobs that left the United States in previous decades, white-collar IT jobs are now leaving the United States as the majority of the world's largest 500 companies outsource overseas. Recently, Sen. Shirley K. Turner (D-N.J.) proposed a bill that would require public agencies to contract only to firms using American-based workers unless the skills necessary could only be procured elsewhere. Other states, including Connecticut, Maryland, Wisconsin, and Missouri are looking at similar legislation, and Nasscom has dispatched a public relations firm and lobbyists to turn political sentiment in the United States. The group is also considering appealing to the World Trade Organization, since Nasscom President Kiran Karnik says such laws amount to nontariff trade barriers. Research firm Gartner suggested recently that Indian software firms take a proactive stance to promote the benefits of overseas outsourcing to the public and not just to corporate clients.
(Access to this site is free; however, first-time visitors must register.)
The Defense Department has awarded over $20 million in contracts to develop the Total Information Awareness (TIA) system, a program that aims to integrate private and public databases so they can be mined for signs of potential terrorist activity. Jan Walker of the Defense Advanced Research Projects Agency (DARPA) reports that 26 bids were submitted, while four companies received contracts; DARPA has outlined five years for TIA development, three of which would be spent on developing ideas and demonstrations, and two to focus on the most promising concepts. Critics of TIA such as Sen. Ron Wyden (D-Ore.) are concerned that the system will be used to spy on innocent citizens and undermine Americans' civil liberties, while the Defense Department responded to this criticism by announcing a TIA oversight panel and denying allegations that it is gathering a massive database. TIA contractors include Raytheon, Telcordia, and Cycorp, which is working on a prototype database; Cycorp President Doug Lenat notes that company researchers have already created a system designed to recognize phone-calling patterns that could be typical of potential overseas terrorists. The contractors note that they are using bogus data in their TIA work.
To read about ACM's reactions to TIA, visit http://www.acm.org/announcements/tia.html.
An international team of physicists raised the bar for high-performance computing last November by sending 6.7 GB of uncompressed data at 923 Mbps between California and Amsterdam in 58 seconds using the Internet2 broadband network. The transfer took place at a rate 3,500 times faster than an average household broadband connection; the California PC ran RedHat Linux and the Amsterdam-based PC ran Debian GNU/Linux. Data transmission was handled by 9,000-byte jumbo frames, which outsize the packets usually sent over the Internet by a factor of six, while a router was supplied by Cisco. Stanford Linear Accelerator Center director of computer services Les Cottrell says such speed upgrades are essential if physics researchers around the world are to share knowledge and collaborate in real time, especially with terabytes of data being generated each day. High-speed computing, for example, will be critical if American scientists are to access data gathered by the Large Hadron Collider (LHC) in Switzerland, notes Internet2's Greg Wood. Cottrell adds that high-speed data transfer will also be a boon to the fields of astronomy, the Human Genome Project, and telemedicine. The international team hopes to beat their speed record through a collaborative project with Intel and the Los Alamos National Laboratory.
A team of scientists from several universities and research institutes have derived a way to coordinate more closely massive parallel processing applications from models found in nature. The researchers studied the growth of crystals and used a mathematical equation from that process to keep parallel processing in sync. Simulating large battlefield scenarios or managing cell phone networks requires huge amounts of processing power and programs that distribute the workload among connected machines. Keeping those distributed operations running smoothly and in sync has previously been achieved by central systems, but the newly discovered method found a more efficient way that does not use central management. Instead, each computer in the network is linked to those nearest it, as well as to one other random computer further away. The result is a small-world network similar to the social networks that allegedly link every person on the planet through six degrees of separation. The computers do not have to wait for the entire group to come into sync periodically, as with traditional models, but only have to check with one other computer. How closely the processing is synched can be varied with the frequency of the checks, which is controllable through the equation used. The research team found that the system model scales well to large networks and is likely to be ready for application in two years. Researchers involved in the project are from Mississippi State University, Rensselaer Polytechnic Institute, Los Alamos National Laboratory, and Florida State University.
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Dire predictions of terrorists launching "an electronic digital Pearl Harbor" against critical U.S. infrastructure espoused by former White House cybersecurity adviser Richard Clarke and others are being disputed by some experts, given the complexities involved in launching a coordinated cyberattack and a shortfall of technical skills in potential terrorist states. Center for Strategic and International Studies analyst James Lewis downplays Internet security problems, noting that essential U.S. networks are far more heterogeneous, profuse, redundant, and capable of self-repair than alarmists have indicated. He adds that the intricacy of critical infrastructure systems--some of which are very old and are separate from the Internet--is another barrier. "A hacker or even a large group of hackers would need to find vulnerabilities in multiple systems to significantly disrupt the power supply, and even then, an attack might only disrupt service for a few hours," Lewis postulates. Righard Zwienenberg of Norman Data Defense Systems reports that cyberterrorists could conceivably cripple the Internet through a global denial of service attack, but notes that they will only have a short window of opportunity to exploit it before computer security firms update their detection software to handle it. Meanwhile, Symantec says in its Internet Security Threat Report for the second half of 2002 that analysis of Internet attacks demonstrates that hackers in possible terrorist nations have insufficient know-how to launch serious cyberattacks, and are further impaired by their reliance on outdated methods. Gartner concludes that such attacks will have minimal impact on the nation, given terrorists' current level of technical proficiency, though Gartner research director French Caldwell predicts that a targeted attack on a critical component of U.S. infrastructure will be developed within the next two years.
The United States is suffering a significant decline of proficient technology professionals--the National Science Foundation declared last week that the number of graduating science and engineering Ph.D.s slipped to 25,509 in 2001, while 41.1 percent of the doctorates were awarded to American citizens, compared to 43.3 percent in 1998. Meanwhile, France, Spain, China, Russia, India, and other countries are becoming more competitive in their research and development push. The United States is also outsourcing many tech operations to nations with lower labor rates in an effort to cut costs. The United States should adopt a three-pronged strategy in order to revive its tech workforce, writes Michael Kanellos. Invigorating the educational system to lure more high-school graduates to the science and engineering fields is one step. Key to this is clarifying such fields to students. Another step is to encourage the emigration of foreign students and workers to the United States by awarding green cards to graduates and Ph.D.s, for instance. The third stratagem is for the country to analyze its basic tech strengths, such as project management and marketing.
At the recent VSLive show in San Francisco, industry veterans Alan Brown and Alan Cooper discussed many of the problems endemic to software project management. Cooper, who is thought to have fathered the Visual Basic programming language, said that software programmers are frequently mislabeled as engineers, the difference being that engineers find solutions while programmers implement them. "Web designers are called programmers, programmers are called engineers, and engineers are called architects, and architects don't seem to ever get called," he exclaimed. Brown, who directs Rational Software's Rational Development Accelerator Initiative, noted that productivity could be significantly improved through component-based development so that software can be reused across disparate projects. He argued that at one end of the project management spectrum are projects developed according to individual input, and at the other are teams that operate consistently and predictably, and follow an unchanging life cycle. Cooper said that software developers generally work without supervision, which is a recipe for disaster; he advised that software projects should include people who have users' needs in mind to keep developers on track. Furthermore, he pointed out that an "adversarial relationship" between managers and programmers often leads to inaccurate time estimates.
The buildup of obsolete electronics in landfills can be reduced significantly thanks to a bevy of recycling and reuse programs, some of which are organized by computer manufacturers themselves. For instance, owners of old computers can visit Dell's Dellexchange.com and choose to either auction off their hardware, donate it to a nonprofit, exchange it for a newer model, or recycle it. Meanwhile, Best Buy customers with old electronics can drop them off at annual recycling events held by several stores nationwide. Cell phone makers such as AT&T allow people to turn in outdated products at their retail outlets. Montgomery County, Md., has a permanent place to drop off spent electronics in Rockville, which is managed through its Computer Recycling Program. Recycling the plastic components of electronics is difficult, and one alternative is to use a biodegradable polymer, according to Philip DeShong of the University of Maryland. Some manufacturers are designing more environmentally-friendly products, such as smaller cell phones and desktops with lead-free flat screen monitors. However, the EPA estimates that over 3.2 million tons of used electronics are dumped in landfills each year, while only 11 percent of obsolete computers were recycled in 2001. Proponents such as DeShong advocate a two-pronged strategy for electronics recycling: Manufacturers must design their products to be less detrimental to the environment, while consumers must adopt better recycling habits.
Accenture researchers Dana Le and Owen Richter have created a prototype portable computer that can record conversations, what time they took place, and the location where they occurred. The device, known as a personal awareness assistant, could be used to remind users of critical information gleaned during social interactions--people's names, phone numbers, and so on--without being too obtrusive, according to Le. The first prototypes included a wearable computer with Global Positioning System (GPS) electronics, speech recognition software, an earbud, and two microphones, one of which records ambient sound in a 30-second loop while the other records user cues. The device's refinement was largely based on two realizations: That people are more comfortable carrying cell phone-like devices and earbud accessories rather than a full computer, and only keeping audio files on the device allows it to be less intrusive. Richter says his lab created the personal awareness system to demonstrate future technology to Accenture customers rather than for commercial gain. The Accenture researchers say the most obvious application for the device would use the location-stamping feature, such as to remind wearers to buy products whenever they are near a grocery store; another would be to enhance collaboration by having one person feed information to the wearer via the earbud. However, Steve Mann of the University of Toronto says that many people are uncomfortable wearing earbuds, and is skeptical that audio information alone is enough to support collaboration and other activities. Meanwhile, Charmed Technology COO Joe DeVita muses that the technology's adoption by mainstream users could be hampered, since recording conversations are often viewed as a violation of privacy.
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Perl creator Larry Wall is gearing up for a dramatic makeover of the programming language that resembles natural language in many ways. For version 6, Wall has taken more than 300 requests for change into consideration, from what some consider to be the most dedicated and innovative development community. In his design documents released to the public, Wall has hinted at the changes to be implemented. Nat Torkington, Perl project manager for version 6, says the new iteration will clear out some outdated legacy code that made previous versions of Perl backwards compatible, but complicated the integration of new features. Perl 6 will also have support for some more recent features, such as threading and Unicode, built in from the ground up, with the help of a new interpreter called Parrot. Torkington also says the new regular expressions in Perl 6 add capabilities and make adapting the language to newer technologies easier. However, those involved in the project do not expect Perl 6 to gain fast popularity, and instead expect a gradual migration over several years, similar to how businesses moved from Perl 4 to Perl 5. Perl expert Randal Schwartz says that development on Perl 5 will continue from the most current stable version, Perl 5.8, to Perl 5.10 and even Perl 5.12, since developers realize businesses cannot easily switch over to new platforms for their mission-critical applications.
The Immigration and Naturalization Service's annual report estimates that approximately 17 percent of 1,064,318 immigrants who were granted permanent residence in the United States in fiscal 2001 were admitted under employment-based preferences, and only 7.9 percent of that number qualified under a category requiring at least a bachelor degree. Some people in this category were brought in on H-1B visas. The percentage of immigrants in the U.S. population--8 percent--is at its lowest point in almost 80 years. The United States should develop programs to attract more immigrants with IT skills, as the European Economic Commission has done, writes Ronald A. Zisman. He adds that qualifications for U.S. immigration should include being highly educated, first-generation professionals capable of earning high incomes and who pass their work ethic on to their children. Zisman argues that critics concentrating on H-1B workers are overlooking a transformative event in the technology industry--global software development outsourcing, which is being spurred by increasing numbers of educated workers overseas, falling product manufacturing costs, and Internet-based transfer of modular technology. Both European and American companies are outsourcing to overseas firms or building in-house offshore sites, which is significantly reducing the incidence of "bodyshopping" that ran rampant during the IT boom of the 1990s. U.S. companies were expected to spend $7 billion on global software outsourcing in 2002, up from $5.5 billion in 2000.
Former Forbes ASAP editor and author of "The Microprocessor: A Biography" Michael S. Malone warns that the high-tech industry's fixation on Moore's Law, which dictates that processing power and chip density double every 18 months, is an invitation to disaster. He does not doubt the veracity of Moore's Law, but writes that re-invigorating the electronics industry should be of greater concern. Malone argues that blind adherence to Moore's Law by entrepreneurs hoping to capitalize on e-commerce--which was encouraged by investors, stock markets, and venture capitalists--led to the dot-com boom and bust and the resulting economic fallout. A similar meltdown occurred in the telecommunications sector, while the biotechnology industry is on track to suffer the same fate. Malone points out that many high-tech experts are realizing that the evolution of business and society cannot keep pace with physics. He cites Google CEO Eric Schmidt's announcement several months ago that his company will not adopt the Itanium superchip as a watershed event that symbolizes a major change in thinking away from Moore's Law. Google has opted instead to embed smaller and less expensive chips in future servers because Schmidt says he is after "maximum functionality" rather than "maximum power." Companies that do not recognize this revolutionary shift in thinking will suffer greatly, predicts Netscape co-founder Marc Andreessen.
At an IEEE 802.15.3a Task Group conference held last month in Florida, a group of five companies organized its own forum to mull an ultrawideband (UWB) standard involving multiband technology. However, most ultrawideband developers favor a singleband approach and have devoted considerable resources to its development. The group, consisting of Intel, Discrete Time, Time Domain, General Atomics, and Wisair, all decided separately that "It's going to be difficult to deploy this commercially as singleband," according to Mark Bowles of Discrete Time. At present, the FCC allows UWB equipment to run in the 7.5 GHz-wide transmission band. In contrast, multiband technology splits the spectrum into 500 MHz bands that work together to skirt data around interference from outside systems. Ben Manny of Intel Research and Development says multiband technology is advantageous because it can work with multiple systems (especially with 802.11a-based WLANs), can scale to fit faster data rates in coming years, and is flexible enough to adjust to various spectrums worldwide. On the other hand, a multiband approach is more difficult, costly, and power-hungry than singleband technology. The informal coalition will have opportunities to formally present its proposals to IEEE in March and July, but an official standard could take up to 18 months to be established.
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Kris Hammond, founder and director of Northwestern University's Intelligent Information Laboratory (InfoLab) and Information Technology Development Laboratory (DevLab), studied and developed artificial intelligence for 12 years at the University of Chicago, and moved to Northwestern to apply his research to real-world problems. He says the purpose of InfoLab is "to reduce the friction that people constantly encounter when trying to find information, both online and offline" through a combination of artificial intelligence, information retrieval, and cognitive science. Hammond founded DevLab as a facility to help transfer academically-developed technologies to the commercial sector and build thriving, Chicago-based tech businesses; both labs dovetail with Northwestern's goal of nurturing students' programming and software engineering skills. He says "our students would like to know how to be not just programmers, but software engineers." Projects under development that Hammond thinks hold great potential include Watson, an information retrieval system that employs artificial intelligence, and a program incorporated into a TiVo box that collates closed-caption information from TV programs and presents relevant data in a micro-site built in real time. Hammond thinks the local business community would benefit significantly by using the university as a resource to solve problems, while academics would gain a better knowledge of business problems. He says that DevLab's chief purpose right now is to build value rather than make money, and praises Northwestern for not subscribing to the traditional license-and-leave practices of many tech transfer programs.
Dr. Gordon Moore, the co-founder of Intel, said his dictum that semiconductor density would continue to double every two years will remain true for another decade at least. After that, he said advances in silicon-based computing may slow, but there is no brick wall engineers' creativity cannot surmount. Moore spoke at the International Solid-State Circuits Conference's 50th anniversary meeting in San Francisco. "No exponential is forever," he told the gathering. "Your job is to delay forever." Heat and power leakage are the most dangerous threats to Moore's Law, he said, warning that a laptop requiring a kilowatt of electricity would be "very uncomfortable." Recently, Red Herring magazine reported that Moore's Law threatened the viability of the semiconductor industry since consumers would not be willing to pay for maximum performance when they already have access to suitable functionality (see news item above). Moore said such thinking did not take into account the cost-reduction aspect of rapid technological advance, and said as long as the speed of innovation kept up, companies necessarily had to compete on that front. He also said alternative platforms such as nanotechnology, molecular computing, and quantum computing would not be able to displace silicon technology for a long while, and estimated a cumulative $100 billion had been spent on silicon development to date. However, Moore did say that those technologies would likely supplement silicon-based computing eventually.
The rapidly growing tide of junk email, or spam, is inundating ISPs, infringing on email users' privacy, and eroding people's trust in the Internet, and thus far efforts to control it through grass-roots activism, spam filtering software, and legislation have been ineffective. Spammers have been aided by the email explosion of the early 1990s, as well as by service providers hungry for market share and the Internet's relatively open architecture. The FTC keeps a vast database of spam samples submitted by consumers, yet cannot really put pressure on spammers, since spam is not considered obvious fraud and therefore unlawful, despite the fact that spammers use deceptive means to evade being tracked down. Popular spam filtering programs become less effective as time goes on, because spammers are constantly looking for new ways to circumvent such blocks. Another problem with filtering programs, be they built into email programs by ISPs or developed by independent programmers, is the risk of them blocking legitimate email; solutions that may reduce the occurrence of false positives include programs such as SpamAssassin, which labels email as spam using an ever-growing system of rules and points, such as the appearance of certain words, requests for credit card numbers, etc. A more recent filtering technique is probabilistic filtering, in which the software tracks all words in each email and determines their statistical probabilities as spam-indicators--but even this method is not foolproof. Anti-spam legislation has been stymied by both corporate marketers and Internet supporters' reluctance to accept government regulation, although the Direct Marketing Association recently admitted that a lack of legal safeguards will be detrimental to legitimate marketers. Consumer Project on Technology director James Love argues that fining spammers would be an effective deterrent, as would an international anti-spam treaty; another, simpler solution would be to make it illegal to forge Internet headers and require unsolicited bulk email to be tagged as such.
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Despite its recognition as a hardware company, Intel also is a formidable software operation with more than 6,000 programmers in its ranks. Late last year, Intel created four Intel senior fellow positions at the top of its research division, two of them going to director of microprocessor research, Justin R. Rattner, and general manager of software and solutions, Richard Wirt. The pair say compiler software is becoming more effective through OpenMP, which allows programmers to prepare the code for hyperthreading and multithreading beforehand, and through dynamic compilers, which will optimize operations even as the program is running. Rattner says the key to this type of dynamic optimization is program instrumentation that gives the compiler visibility into runtime execution. Wirt says Intel aims to build more and more parallelism into its hardware; first through threaded single processor operations, then by placing multiple threaded processors on the motherboard, and finally through huge strings of multi-core processors. Existing applications can take advantage of this parallel processing with helper threads that line up data that is usually missing and make it ready for the main thread, yielding between 1.3 times and 1.6 times performance boosts on average. Wirt says Simple Object Access Protocol (SOAP) on the commercial side and Message Passing Interface (MPI) on the technical side will let application functions work together in a large distributed computing environment.
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The U.S. entertainment industry has conducted a long and often frustrating legal campaign to shutter the popular Kazaa file-sharing service, and been thwarted at many turns by Kazaa's decentralized operational structure, which is spread out across several nations. The software Kazaa uses is located in Estonia and on a remote island off the British coast; the Kazaa.com domain is registered to LEF Interactive in Australia; and Kazaa's interface, FastTrack, is now owned by Sharman Networks, which is based on the island republic of Vanuatu and runs its servers in Denmark. Attempts by Hollywood lawyers to root out Sharman's investors and board members were deflected because Vanuatu is a haven for maintaining business confidentiality, but this did not stop them from seeking out Sharman CEO and LEF Director Nikki Hemming, who eventually was deposed in Canada. At a hearing in late November, U.S. District Court Judge Stephen Wilson believed there was a case of jurisdiction against Sharman, but Sharman, in anticipation of such a ruling, has been trying to change its image by bundling Kazaa with the Altnet peer-to-peer network, which compensates copyright owners for use of their works and gives them control over their distribution. The prosecution dismissed this claim for legitimacy as a delaying tactic to sell more advertising. Brilliant Digital Entertainment CEO Kevin Bermeister believes that Altnet could be used to encourage more sharing of sanctioned content if Hollywood comes aboard, but the fact remains that the number of downloadable files on Altnet pales in comparison to the volumes of files Kazaa offers for free. Furthermore, the wider appeal of Kazaa's services brings in more users, expanding Sharman's consumer base and revenue opportunities.
A roundtable of technology experts debated how computers are encroaching on the engineering profession by automating engineering tasks, and what this holds for the future. When asked what he thinks is the most significant effect computers have had, Stevens Institute of Technology professor Lawrence Bernstein described a revolution in structural design that has led to, among other things, earthquake-resistant buildings in Japan; he also anticipated a bioengineering explosion soon thanks to the use of computers in analyzing proteins, RNA, and DNA. Meanwhile, Columbia University professor Al Aho, formerly of Bell Laboratories, said he foresees a time when machines and human beings are interchangeable, and believes that computers with computational power and memory equal to that of human beings will emerge within 20 to 30 years. However, consultant Jeff Harrow did not think computers are "anywhere close" to supplanting engineers, because they lack creativity and are chiefly concerned with carrying out "scut work." In his opinion, the most exciting trend in computing is the application of computers beyond the computing field, computerized surgery being an example. Nicholas Donofrio of IBM said computers play a key role in designing new computers, and forecasted that they will be able to learn more from people in the future; he was very excited that computers are replacing physical construction and testing of products via simulation, which greatly streamlines the development process. Harrow, Aho, Donofrio, and others maintained that there will always be a need for engineers for a number of reasons, including the flood of new ideas and the widening of the field's scope. Harrow said, "[I]f we ever get to the point where there's nobody who understands what...[computers do], we're in deep trouble, because then we'll never be able to make any additional moves forward." He also speculated that the move to biologic computers could spawn self-replicating machines.
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