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MRI and mammograms as annual checkup post-treatment?
- Question from Radha: Do you recommend MRI along with mammograms as part of the annual checkup, for someone who has had triple-negative breast cancer high grade, stage I, who has been through the standard AC plus radiation treatment after lumpectomy? ACS recommends MRI be done in high-risk survivors. Insurance is not likely to agree even if the oncologist agrees to do it. Should one try to insist on MRI as part of the testing?
- Answers - George Sledge, M.D. I think the MRI recommendations made by the American Cancer Society (ACS) are reasonable. In essence, the ACS has recommended MRIs for women who are BRCA1 or BRCA2 mutation carriers, or women who have a lifetime risk of breast cancer of 20% or greater. I think certainly for standard screening, I only recommend MRI for such really high-risk women. For a woman who has already had breast cancer, such as the case you describe, there is no striking reason to believe that that would need to be imaged in a different way than the normal breast cancer patient. It is important to recognize that for any woman with an invasive breast cancer, the greatest risk is not the risk of a secondary breast cancer tumor but rather the risk of a distant metastasis of her first breast cancer. So while continuing imaging of the breast is important, that is likely to be determined by whether or not she has had appropriate therapy to prevent a systemic recurrence.
- Beth Baughman DuPree, M.D., F.A.C.S. I agree with the ACS recommendation in the BRCA-positive patients and women with a 20% risk. The other subgroup that I will use MRI for screening is the group of women whose breast cancers were undetectable by mammography, whose mammograms didn't reveal the primary tumor. This is typically a group of women whose mammograms reveal very dense fibroglandular tissue that reduces the sensitivity to detecting an ipsilateral [same breast] recurrence or a contralateral [other breast] primary cancer. This is a small subset of patients, but the inability for the mammogram to have detected the first cancer decreases my confidence in the mammogram to be used as that patient's only screening tool.
The Ask-the-Expert Online Conference called Triple-Negative Breast Cancer featured George Sledge, M.D. and Beth Baughman DuPree, M.D., F.A.C.S. answering your questions about triple-negative breast cancer and its treatment.
Editor's Note: This conference took place in July 2008.
The materials presented in these conferences do not necessarily reflect the views of Breastcancer.org. A qualified healthcare professional should be consulted before using any therapeutic product or regimen discussed. All readers should verify all information and data before employing any therapies described here.
A production of LiveWorld, Inc.
Copyright 2010. All rights reserved.


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Pond Owners Learn How to Solve Common Pond Issues
Submitted by alexmerk on Wed, 06/05/2013 - 14:04
Pond owners from Lee and Henry counties enjoyed an evening ouside learning how to care for and maintain a healthy ecosystem for their pond wildlife, fish, and plants. Allen Pattillo, Natural Resource Ecology and Management Extension Program Specialist answered questions and discussed common issues at a local pond in Henry County.
Here are pictures from the Pond Management meeting:
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2nd Annual Robert A. Wise Chili Cook Off
Event Dates and Times
11 a.m
National Guard Armory, 1225 Easterwood Drive, Tallahassee, FL
The 2nd Annual Robert A. Wise Chili Cook Off will be held Saturday, November 9 at 11 a.m. at the National Guard Armory, 1225 Easterwood Drive, Tallahassee. Held in memory of a local soldier who gave all for his nation, this event honors all who have served and sacrificed. Event proceeds will benefit Honor Flight Tallahassee and the Collegiate Veterans Association at FSU.
The entry fee for a team is $20 and participants are encouraged to register early. Entry forms and complete rules can be found at the 2nd Annual Robert Wise Chili Cook Off page on Facebook or by emailing firstname.lastname@example.com. Cash prizes or trophies will be awarded in several categories.
Admission is $10 in advance or $12 on the day of the event. Ticket includes chili and two beverages (beer, water or soda.) Kids 12 and under are free.
We will also have college football on TV, music and kid's activities.
MSG John Condo
Facebook: 2nd Annual Robert Wise Chili Cook Off
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The purpose of this blog is to help focus the immigration challenge through reporting on this critical topic. We aim to put a human face on this issue, to offer strategies to raise awareness, to catechize, to mobilize and to inspire one another to make our voices heard.
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If there's one thing federal Tories hate more than Thomas Mulcair's facial foliage, it's a carbon tax.
Perhaps unaware that Her Majesty's loyal subjects in beautiful British Columbia are still standing, despite a levy on carbon use, including gas at the pump, since 2008, the Conservatives repeatedly dismiss such a tax as the Darth Vader of economic destroyers.
"It would impact on virtually everything and the cost of living of all Canadians," stormed federal Environment Minister Peter Kent, during a recent, late-night yawn fest in the House of Commons, known to parliamentary insiders as the committee of the whole shebang.
"Let me clear the air [hehe]once again, Mr. Chair [see Romper Room, 1962] This government will not now or in the future impose a carbon tax on Canadians."
Chimed in mild-mannered Mr. Kent's Daily Planet colleague Michelle Rempel: "A carbon tax is a tax on everything, that would hurt jobs in this country, and our government will not do that."
This followed Foreign Affairs Minister John Baird's rant a few days earlier that a carbon tax is so lethal, imposing it would actually "kill and hurt Canadian families."
Now that's scary. Has something dire been happening in carbon-taxed British Columbia that we don't know about? Is Premier Christy Clark's vaunted "Families First" agenda just a cover-up to mask a hidden body count of families, asphyxiated by paying an extra 7.2 cents a litre for gas?
Yet there was our Premier this week, freshly returned from her sojourn to Seoul, journey to Japan and march on Manila, still espousing "well-paying jobs for B.C. families," even at the risk of death via carbon tax.
Definitely more frightening than the beard of Thomas Mulcair.
The apprenticeship of Tony Clement
By the way, if you're wondering where hard-hearted Treasury Board President Tony Clement schooled himself in saying "no" to so many worthy ventures, other than those in his own riding, the secret is out.
As a callow youth, Mr. Clement earned money as an usher at the Ontario Film Institute auditorium. "I had to shine my flashlight on old ladies crumpling their lozenges a little too loudly," he told a reporter.
Say no more.
The magic of Matisse
Excuse me for buzzing. I'm still lost in the magic of Matisse.
Imagine seeing a collection of the brilliant French artist, as I did at a preview on Thursday, right here in good old Vancouver, a mere block from where I work.
There's even a local angle to the stunning exhibition of paintings, mostly Matisse, collected by the wealthy Cone Sisters of Baltimore, who were long dead before The Wire came along to show a different side of Babe Ruth's hometown.
In the early 1950s, Vancouver Art Gallery curator J.A. Morris thought he had a Canadian coup for the young institution – an agreement to transfer a number of paintings by the incomparable Matisse from an exhibition in Los Angeles for a special showing here.
Alas, at the last moment, Matisse, then in his early 80s, fell ill. He asked for his world-class works to be sent back to France, before they could be displayed in Vancouver.
Mr. Morris was heartbroken. He tried to save the show with a direct appeal to the painter himself. Cleverly, the VAG curator wrote his letter in French, playing up that Canada, as a bilingual country, had special ties with France.
The aging artist, who died two years later, was touched. He responded with a personal, typewritten letter from his Riviera residence to Mr. Morris on West Georgia Street, expressing regret that it was too late to reconsider. At the bottom is the distinctive signature that identified all those framed, vibrant splashes of colour and craftsmanship that hang in museums around the world.
The Morris-Matisse exchange is on display as part of the Matisse collection, which opens Saturday at the Vancouver Art Gallery. Guaranteed to enchant your socks off.
Besides, where else can you see a painting entitled Large Odalisque in Striped Pantaloons?
Yes, about time, but let's still applaud the choice of former NDP premier Dave Barrett to receive the Order of British Columbia.
As colourful and impassioned a politician as ever there was, Mr. Barrett rarely held back his left-wing views. And he joked incessantly. Claiming to be bilingual, he once quipped: "I speak fluent capitalism and fluent socialism." No one disagreed.
The old ball game
Did you hear that federal Labour Minister Lisa Raitt was at a Blue Jays game the other day? When the umpire hollered, "Strike!" Ms. Raitt took the next flight back to Ottawa to prepare back-to-work legislation.Report Typo/Error
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The alluringly warm water is just steps away from your luxurious accommodations, and offers many opportunities for relaxation, or excitement. Your experience will be shared with playful dolphins, manatees, pelicans, egrets, osprey, seagulls and a variety of shorebirds. Walk the beach, stretch out in the sun or enjoy fishing, boating, Kayaking, and many other local water activities. The tropical climate makes outdoor activity available and enjoyable nearly year-round. Wherever you go and whatever you do you'll experience the island hospitality that brings people to Siesta Key and the Gulf & Bay Club year after year.
Located right on Siesta Key Florida, Turtle Beach Marina is the only full service marina, restaurant and bar on Siesta Key. Siesta Key is known for some of the greatest fishing in the Gulf, if not the United States. The fishing, whether from a kayak, pontoon boat, or our center console boat, is second to none.
Florida Boater's Guide
Siesta Key Marina
Canoeing and kayaking, with dozens of canals and inland waterways giving rowers access to the Sarasota area that is inhabited only by wildlife.
Located in the Siesta Village, Robin Hood Rentals offers discounts to any Gulf and Bay Resident who wants to rent, as well as offer delivery to Gulf and Bay.
Sarasota Fishing Charters
If you are looking for fun on the gulf coast of Florida, it's CB's Saltwater Outfitters on Siesta Key. You can find everything you are looking for, from fishing tackle to sunglasses & flip flops or a day on the water.
The Gulf of Mexico waters off Sarasota and Siesta Key has a large variety of charter fishing options and we target the best deep sea fishing grounds at any time of the year maximizing the chance of a superb catch and having a an enjoyable time out on the water.
Charter fishing at Siesta Key, enjoy offshore sport fishing charters with Double Nickel. Affordable prices for both experienced and family/kid orientated fishing charter trips. The Double Nickel, Siesta Key deep sea charter fishing boat offers half day fishing charters, 6 hour fishing trips, full day charter fishing trips, extended charter fishing and sport fishing charter trips for parties of up to six people. We also cater to families with small children and we arrange group offshore sport fishing charter trips from Siesta Key with advance notice.


text: Pop Culture Duff Beer 24 Can Pack Lacrosse Playground / February 4, 2012 You've slaved away all day at the power plant. It's time for a beer! So grab yourself a cold one from the Duff Beer 24 Can Pack and celebrate like everyone's favorite All-American layabout. Based on the iconic beer Continue Reading Share


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To illustrate how you may benefit from OTRC membership, we will briefly identify some of the principal functions that we fulfill:
1. OTRC serves as a disseminator of information, passing along announcements of tobacco-related grant opportunities, major new research findings from within and outside Oklahoma.In addition, we encourage research that addresses the multi-dimensional aspects of tobacco use, addictions, and treatment in Oklahoma through direct OTRC funding opportunities...OTRC has set up listservs specific to such purposes so that members can see those they wish to and avoid email clutter with those they do not.
2. OTRC hosts presentations and seminars with prominent researchers and policy influentials from inside and outside Oklahoma.In addition to lectures open to the public, we also host small-group breakfast and luncheon seminars on timely and controversial tobacco and nicotine issues, open by invitation only to OTRC members.In addition to their inherent interest, these seminars help to foster the development of useful new collaborations among OTRC colleagues.
3. OTRC's website (http://www.ouhsc.edu/otrc) that identifies OTRC's tobacco and nicotine researchers and briefly describes their areas of interest (with links to their home pages, if they so desire).Specific studies and news events are featured, if and when members wish them to be publicized.Information about the website is distributed to other tobacco researchers and interested journalists and policy makers.
What we ask of you to be listed as a member of OTRC is simply your permission to include your name and the modest bit of information requested on the attached page (most of which we can fill in for you if you submit a recent CV with the form).The success of OTRC for us as individuals, and for our institutions, depends entirely on the OTRC's ability to span the wealth of tobacco and nicotine research resources in Oklahoma.Please click on the Membership Application form, fill it out and submit. If you prefer fill in the contact information Click the Membership box on the form and email your CV/Biosketch to OTRC at email@example.com or by fax at 405-271-2808.
If you are interested in applying for membership, please click link (above).


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I admit it, I look at the headlines of press releases and if interesting, the first paragraph. But three press releases from last week required a revisit because the topics were so...interesting.
First off, Depiction, which offers a "what if" visualization tool announced (press release) at State of the Map apparently (I'm not sure why but I guess it uses OMS?) a new product: DepictionPrep. The idea: it's software to help you and your neighborhood prepare for an upcoming emergency. No details on pricing; it's coming this fall. I have mixed feelings about this and note that Glenn just shared another related offering: Safety Maps which creates a custom "we'll meet here in case of emergency" map for free and is built on OpenStreetMap. And licensed under CC.
Second, Fox, the bike shocks folks joined the Ant+ alliance teamed with and Garmin the GPS folks (press release) to walk users through setting up the suspensions on the their moutain bikes. It's a proof of concept that does not require GPS. As I undrstand it, sensors in the pumps (that serve as shock absorbers best I understand, I'm a road biker) talk to the Garmin Edge and walk the user through the process. You can then save different settings for different terrains. I wonder if this is a solution in search of a problem. I'll have to ask my mountain biking friends.
Finally and this is the most big brother of them all: CrowdOptic (press release) has a platform to keep track of where cell phones are "looking" during an event like a football game or a concert. Then, that information can be used to feed more info (say stats on the player) or ads (Time for a coke!). The release does not say but I'm guessing you'd have to give the company access to your location and compass info. Sadly, this also suggests that at such events people spend a good deal of their time taking pictures from, lookng through or looking at their phones.


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Recent Portfolio Updates
Recent Blog Updates
Pentecost and Baptism
So…this is the third iteration in a series of art pieces. It's only the second piece made for semi public…
Chaos and Disconnection
When I first completed this art piece, heck when I first envisioned the piece, the message behind the…
Beyond the lights
I have been reading a lot about the spiritual/emotional experience of the dark night of the soul. I know I've…
From Fatwa to Jihad by Kenan Malik
"By exploring these myths, Kenan Malik provides an important primer to revaluate the key drivers in current responses to ISIS,…
Uncertainty and Doubt
I've tried writing this a dozen times over the last year at least. So, because I haven't put pen to…


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Anderlecht winger Mbark Boussoufa seems to have welcomed speculation linking him with a move to Newcastle United.
Mbrak Boussoufa – flattered by Newcastle's interest
There has been news this week that Mbark's Belgian club, Anderlecht are keen to keep him and their sponsors KIA Motors of South Korea, have even offered to help with his wages to keep him at the club.
However, today Mbark says he flattered by Newcastle's interest in him:
"I'm flattered by Newcastle's interest. It is always nice to know clubs are watching me." "I spent two years with Chelsea, so I know what English football is all about. I learned a lot from their players, especially Gianfranco Zola."
"I was on the point of breaking into their first team when Roman Abramovich arrived. He signed seven star players, and the youngsters were not given their chance."
"I would not say no to a good offer from England. If Newcastle want me they must first speak to my club – and then I'll gladly listen to what they have to say."
Reports are that Newcastle want an answer to their bid for Mbark by the end of this week. We don 't know if that's true but by Boussoufa's own words he seems quite interested.
In fact saying you are flattered is a come-on to Newcastle, so it may be the chances are high that if Kevin really wants Mbark, he would come to Newcastle.
What do you think?
Comments and opinions welcome.


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McDonalds Diet
Someone decides to lose weight only eating McDonald's meals.Top Rated Diet Shakes of 2017
No, you don't need to have your eyes examined. This really is called the McDonald's Diet, named for the fast-food giant who put french fries and cheeseburgers on the international map. The diet did not come out of one of their test kitchens, but rather the mind of Merab Morgan of North Carolina.
Restricting herself to only 1,400 calories/day, her plan was to eat at Mickey D's three times every day. Over the course of her three-month diet, Morgan lost a little more than 30 pounds.
Do You Know the Best Diet Shakes of 2017?
- Shows you that in moderation, anything is possible
- Sheds a positive light on McDonald's image
- Eating McDonald's every day
- Expensive
- Regular diet of fast food proven to have detrimental health effects
You're probably asking what someone eats on a McDonald's Diet for only 1,400 calories/day. Especially when you consider this - one meal including a Quarter Pounder with cheese, medium fries, medium Coke and an apple pie is a whopping 1,240 calories!
Morgan's diet included a sausage burrito and medium Diet Coke (300 calories, all from the burrito) for breakfast. The rest of the time it was cheeseburgers (300 calories each) and salads (a Southwest Salad with Grilled Chicken has 320 calories).
Morgan's McDonald's Diet was certainly not the first. A New Hampshire woman gave herself a 2,000 calorie McDonald's diet and lost more than 35 pounds. Guinness Book of World Records features Don Gorske, the famed gentleman who has eaten well beyond 19,000 Big Macs since the early '70s. Don's a slender 6', 180 pounds.
However, let's not forget Morgan Spurlock who filmed a 2004 documentary following him on his 30-day, McDonald's-only adventure. We watched his belly expand and health climb to dangerously high blood pressure, cholesterol and other life-threatening illnesses.EXERCISE
No guidance provided or suggested.CONCLUSION
While limiting yourself to a healthy daily caloric intake is advisable, you would be strongly encouraged to speak with your doctor before pursuing a McDonald's Diet. Then be prepared for a scolding.Common Misspellings
Macdonalds, Mcdnalds, Mcdees, Mcd'sHow Does McDonalds Diet Compare?
- Product Name
- User Rating
- Has Good Appetite Suppressant
- Has Only Natural Components
- Good Taste
- 18Shake
(Editor's Choice)
- 97/100
- Yoli YES
- 92/100
- Isagenix
- 83/100
- Ideal Protein
- 71/100
- Vega One
- 66/100
- McDonalds Diet
- /100
User Feedback(Page 1 of 3, 47 total comments)
I've been on this diet for a couple of months and I've lost 20 pounds so far, that being said, I keep the regular diet which I would normally eat, such as a quarter pounder with cheese, add Mac sauce and lettuce, or a big Mac, or a double cheeseburger, add Mac sauce add lettuce, and a large coke, no fries.
On another note, I'm more concerned by all the people drinking diet pop an decaf coffee with this diet. Diet pop has aspartame and aspartame turns in to formaldehyde when your body processes it. Also, decaffinated coffee beans are apparently dipped in paint thinner to make them decafinated,
Wow.....it's been six or seven years and this is still being talked about? It just goes to show what can happen when you make a bet on a construction site. How do you make national news without being arrested?
I another question????
what happened to your breakfeast sandwich??
the one with canadian bacon,
'cheese and egg .....I didn't care for the new bread at all.
why don't you make some of your great coffee drinks with decaf?
so many of us would really like have cappicino ....but are not suppose to have caffine....for medical reasons....
I lost 50LBs on the diet. IT IS NOT BAD FOR YOU. You can have an egg muffin in the morning (NOT THE SAUSAGE) You get a GRILLED Chicken Salad for Lunch and eat a healthy dinner at home or if you're in a hurry eat another salad.
It really is not much different from just eating healthy anywhere else (home) but for people that don't have the time like busy professionals it's a great to know that you can eat healthy even at McDonalds or most restaurants for that matter if you order the right stuff and have portion control (don't eat everything on your plate just because it's there)
For all of you screaming "Watch Super Size Me!", you need to watch "Fat Head". It has some very good points that blow Morgan Spurlock's movie out of the water. I've just started the McDonnald's Diet, and... I'm lovin it!
I actually went on a McDonald's diet in 2004 and it worked quiet well. I wouldn't say it's the healthiest but who cares as long as you are losing weight. In the morning I had a dunkin donuts Coffee Roll (which is larger than a standard donut), then for lunch I had from McD's: Double Cheeseburger(440 calories), McChicken(360 calories, 4 PC nuggets (170 calories). The key was the last food consumed was by 4 PM. I figured I was getting a good amount of protein (50+ grams) so my muscle mass wouldn't break down because of starvation. Diet soda and water were the only thing I drank. So I slept hungry. I shed weight real fast, it was great.
The mcd's diet sounds preTty terrible if you ask me. YOU MAY lose weight but with major health risks DIABETES, HIGH BLOOD PRESSURE AND CHOLESTEROL AND EVEN DEATH! If you want to destroy your body, say hello to mcd's but if u r like me hv the occasional burger - do not live on burgers! Are you out of your minder. No wonder America is the fattests nation!
Wow - it's been over nine months and I'm still eating a cheap moderately low calorie McDonalds lunch every day. McDouble, side salad (I like the Italian dressing) and a parfait is now my mainstay. Meat, bread, dairy, leafy greens and a little bit of fruit. Three bucks!!
And for those that think eating hamburgers leads to clogged arteries, do some research. That is a contentious topic among researchers.
You may look thinner after this diet but how will your clogged arteries look??????...... We all know that you do not have to be over weight to have clogged arteries.....
I love the negativity about this. A carefully chosen diet of McDonald's food is almost certainly better for you than the average American's diet. And it need not be expensive either. I've been doing my lunches at Mickey D's for about six weeks now and have dropped about 10 pounds (172 to 162 @ 5'10"). I eat exclusively from the dollar menu and spend $2-$3 per meal. McDouble, Grilled Spicy Chicken, side salad & Fruit & Walnut salads are my mainstays. I haven't modified my other eating habits except to be a bit more careful about portions sizes.
The end reference to "Super Size Me" and that fellows resulting health concerns is quite irrelevant to the topic. Everyone knows you can eat poorly at McDonalds - or at your local grocery or health food store.
Fast food is terrible for you, ive been running since I was in 3rd grade, and now am a sophmore in highschool, im 6' 120 pounds, my point: RUN AND EXCERCISE youll be in way better shape than slammin down a big mac 3 times a day, eat fruits
mcdonalds di9et is the best i lost 10 pounds in 6 days
best diet in the universe
This is stupid as hell. You'll lose weight on ANY diet restricting the amount of calories you consume. I could eat cake and ice cream, but as long as I'm at a calorie deficit, I'll lose the weight. It'll be unhealthy as hell, expensive, and you'll get sick of it fast, but as long as you're consuming less calories than you're burning, then you will lose weight.
People. Come think. Mcdonalds is no different then your grocery store. You can waddle your big but to the grocery store and buy a package of hamburger, a package of cheese and a bag of hamburger buns. And you can go to Mcdonalds and eat fruits, vegtables. And they get it from the same suppliers as the grocery stores. I am a Restaurant manager there. I know. Its your choice what you eat. When you go into your Mcdonalds, look at how many restaurant manager are in shape. Thats because were are able to make intelligent choice. And guess what? We can eat Mcdonalds for free, EVERYDAY!
I tried the Mc's diet for 3 months and lost 41 pounds. I know I probably could have lost more weight going to the store and buying green food, but some people dont like that. If you going to eat at Mc's anyway, might as well make better food choices there and loose the weight at the same time.
Featured Diets and Supplements
Related Diets: Subway Diet, Fast Food Diet, Eat This Not That, Eat This, Not That for Kids
McDonalds Diet?


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The Kinect. Microsoft's add-on that allows for a controller-free gaming experience. It's different, let's start with that. It definitely separates itself from the Wii's motion controller and the Playstation Move. From menu navigation to in-game actions, everything is done through gestures. But is it accurate? Does it hold up well in games? And how is the launch lineup?
Hopefully you've read my Kinect Preview blog post, and I think a lot of what I wrote in terms of the experience is still true. Regardless, I'll still summarize here.
Setup was a breeze. The Kinect comes with a power adapter for those who have the original 360. If you have the 360 S, it's possible to disconnect the adapter and plug the camera directly into the console. This saves you a power outlet. After turning on my Xbox, the new Xbox Update runs and begins to calibrate your Kinect. You dont really need to do anything but read some directions and press A. The system really does everything itself. It's very easy.
Kinect ID
If you plan on playing a lot (which I hope you do) it's a good idea to go through and create a Kinect ID. This process involves tying your body structure to your profile. After signing in with an account, Kinect will take you through a couple of steps and poses in order to link you with your account. This is for games like Kinect Adventure where you simply walk in front of the camera and it will use your avatar. Same goes for signing in during future sessions.
Gestures & Cursor Movement
Not once did I ever feel like I was fighting with the peripheral. Yes, it takes some getting used to. I've spent so much time with arrows, d-pad, mouses and game controllers that simply moving my arms to navigate was awkward at first. But after a few minutes I was up and moving without any problems.
In my Kinect Preview, I mentioned trying out some games like Joy Ride and Adrenalin Misfits. Those games didn't really capture my attention even though they were really fun. The real standouts were Kinect Adventures and Dance Central. The Kinect camera comes with Kinect Adventures while I had to order Dance Central from Amazon
Dance Central: It is what it's hyped up to be. Not only are you dancing and getting a workout, but you're actually learning moves from the artists' music videos and performances. Harmonix had some great choregraphers working on this, and the development team does a great job with giving the characters fluid animations and awesome style. The main dancing characters fit the songs they are assigned to dance to. Dance Central does a good job of letting you know when you're on and off the beat or dance moves by changing the color of the ring around the character's foot (red is bad, green is nice, white is flawless). I played this for about an hour before my parents and sister came home. They immediately saw it, jumped in, and had a great time. It makes for a great party game when you have friends over and a great workout game when by yourself.
Kinect Adventures: Today I only played Reflex Ridge because that's the one mode I really wanted to squeeze in before bed. I haven't had the chance to really try out the other modes, but I will tomorrow and may provide an update to this. Reflex Ridge will give you a better workout than Dance Central. All the jumping, ducking and stretching will make you tired, but you'll have gotten some great exercise and had fun doing it. Forget the Wii Fit, Kinect is where you'll really get your workout.
As I mentioned before in my preview, there's a little bit of a lag between my gesture and the result on-screen. But I knew that and still felt it offered a fun gaming experience (and it still does). I waited in anticipation for two weeks, and today, I'm not disappointed at all. Yes, there are a ton of valid concerns about the Kinect featuring hardcore games. To be honest, I'm doubtful that they will be successful. The Kinect is best suited for casual games, and it will probably stay that way.
At $150, the Kinect is quite expensive. Unless you've tried Kinect and Dance Central and absolutely love it, or you don't mind casual games, it might be wise to hold off on the purchase and wait for developers to release more games. If you want to exercise and have fun doing it, I highly recommend the Kinect. I was sure I wanted to spend the money on it because I had tried it out beforehand. I think it's a great add-on to the 360 and beats out anything I've seen for the Move and Wii. If you're considering it, I suggest trying it out before making a decision.


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What does the term five by five in a radio check mean, and where did it come from?
Mark Matthews responds:
The term five by five refers to the two measures of signal strength and readability; it is derived from older HAM radio instruments that were scaled from zero to 10 with 10 being the strongest. A five by five would be interpreted as 50 percent signal strength and easily readable, perhaps with some static or band clutter. A 10 by two would have a strong signal, but be broken and hard to understand, while a two by 10 would contain a weak signal, but be perfectly clear. A 10 by 10 would be very strong and crystal clear.
Mark Matthews
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About Phoenix
Recognised R&D Centre
Make-in-India Products
The Impact
This advanced treatment for jaundice in newborns
Jaundice is the primary reason why newborns are readmitted to hospitals worldwide, and millions are not receiving effective treatment.Award-winning medical device nonprofit D-Rev launched its latest newborn product this year — Brilliance Pro, an advanced version of its Brilliance Classic product from 2012, which treats newborn jaundice with sophisticated phototherapy.
The Next Gen CPAP
Wouldn't you love an intelligent machine which shares the same passion as yours to save a baby from RDS?
Neonatal RDS occurs in infants whose lungs have not yet fully developed. Respiratory distress syndrome (RDS) is a major contributor to neonatal mortality worldwide.
Most cases of RDS occur in babies born before 37 weeks. The less the lungs are developed, the higher the chance of RDS after birth.
The objective was to bring a next generation neonatal respiration support device and ultimately decrease the rates of RDS-specific mortality.
Mondiale LifePod
Each year eight million children die before their 5th birthday.
Three million of these deaths occur in the first 28 days and there is nothing more saddening than to watch helplessly as a new born babies life ends before it had had a chance at life. It doesn't have to be this way. Many of these deaths are preventable if babies are placed in the safety and warmth of a neonatal incubator.
Spinning the wheel of empowerment
A person with lower limb disability may have to use a wheel chair for the entire life. In a conventional wheelchair the user spends time in a seated position all the time. This constraint gives rise to many physical as well as mental health related issues such as sore body, building of pressure points leading to pressure sores, lowered blood circulation, and dependence on other people for basic needs. One solution to this problem is to provide mechanisms in the wheel-chair to assist the person to stand.
Refreshable Braille Display
Refreshable Braille Display (RBD) is a device that enables people with visually impairment to read digital text through tactile interface. Textual content in Portable Document Format (PDF), word documents etc. can be read using the display without having to emboss/print on braille paper.
Free from the demerits of both auditory devices and paper-embossed braille and at a price point below one-seventh of that of commercially available displays, RBD has been developed deeper penetration in both developed and developing countries.
Dr. Emanuel C Gracias
"The Phoenix DT 100 is an excellent delivery table. The patient can lie on it for several hours without any discomfort. The mattress is long lasting and easy to disinfect. The movements of the table are smooth and it is easy to operate. There hasn't been any breakdown issue"
Dr. Shrinath Mugali
I have been using Phoenix infant care systems and resuscitation unit since 2001. CFL Phototherapy until 2004 and other equipment since 2004.They are in excellent condition . Service is too good and fast. I wish them all good luck for the future.
Dr. R. Shanmugasundaram
I have been associated with Phoenix from the day of its inception. Quality has never taken a back seat in Phoenix products. I wish them all the best.
Times of India, Economic Times, The Wall Street Journal, Hindu Business line and more have featured Phoenix Medical Systems showcasing our approach, effort and impact.


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Public hearing set for 'Tallmadge Town Center' project
The Tallmadge Planning and Zoning Commission scheduled a public hearing for a real estate developer's request for a conditional zoning certificate for a property near the Circle.
The public hearing is set to take place at 7:02 p.m., March 6, at City Hall.
Mota Design Group Inc., a company affiliated with Testa Companies of Cuyahoga Falls, is requesting a conditional zoning certificate for a portion of the property at 76 North Ave., the lot to the north of the city's municipal building. The change in zoning is for the second of three phases of its planned mixed-use development called "Village at Town Center."
The developer has requested conditional zoning that would allow buildings for medical, office and child and adult daycares.
During the public hearing, the Commission will allow the developer to speak about its plans for Phase II and the public to comment about the request.


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Awaken and Replenish shampoo & conditioner! Hair loss and hair growth shampoo and conditioner with natural Trichogen botanical extract formula for thin & thinning hair. Deep cleans while building body, volume and thickness!
Deep conditioning that helps hair look and feel thicker. Ideal for thin hair, thinning, and hair loss. Trichogen extract formula, panthenol and herbal extracts excite and stimulate scalp circulation. Ideal for men and women.
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Bioten's best-selling hair growth products for faster growing hair! Shampoo, conditioner, and hair vitamins enriched with Biotin, extracts, panthenol, Emu Oil and a complex of 17 natural amino acids, vitamins and minerals to get your hair fast and strong!
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text: CALGARY, April 2, 2012 /PRNewswire/ - Oncolytics Biotech Inc. ("Oncolytics") (TSX:ONC, NASDAQ:ONCY) announced today that it has completed enrollment in the first, 80 patient stage of its Phase III clinical trial examining REOLYSIN ® in combination with paclitaxel and carboplatin in patients with platinum-refractory head and neck cancers (REO 018). "This is an important milestone for this study," said Dr. Brad Thompson, President and CEO of Oncolytics. "A data analysis that will involve examining evolving progression free survival will now be performed on this patient group to determine the probability of success in the second stage of the study." The randomized, two-arm, double-blind, multi-centre, two-stage, adaptive Phase III trial will assess the intravenous administration of REOLYSIN with the chemotherapy combination of paclitaxel and carboplatin versus the chemotherapy alone in patients with metastatic or recurrent squamous cell carcinoma of the head and neck, or squamous cell cancer of the nasopharynx, who have progressed on or after prior platinum-based chemotherapy. All patients will receive treatment every three weeks (21 day cycles) with paclitaxel and carboplatin and will also receive, on a blinded basis, either intravenous placebo or intravenous REOLYSIN. All dosing takes place in the first five days of each cycle, with all patients receiving standard intravenous doses of paclitaxel and carboplatin on day one only, and on days one through five, either intravenous placebo or intravenous REOLYSIN at a dose of 3x10 10 TCID 50. Patients may continue to receive the trial combination therapy for up to eight, 21-day cycles and, thereafter, blinded placebo or blinded REOLYSIN until the patient has progressive disease or meets other criteria for removal from the trial. The primary endpoint for the trial is overall survival (OS). Secondary endpoints include progression free survival (PFS), objective response rate (complete response (CR) + partial response (PR)) and duration of response, and safety and tolerability of REOLYSIN when administered in combination with paclitaxel and carboplatin. The first stage of the trial is non-adaptive, and was designed to enroll 80 patients. The second stage is adaptive, and is designed to enroll between 100 and 400 patients with the most probable statistical enrollment being 195 patients in this stage. This adaptive trial design allows data evaluation to determine if the probability of reaching a statistically significant endpoint has been achieved.


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Youth Arts Program – Studio 93, for Children Ages 6 to 13
Bell Arts Factory's after-school and Saturday art programs provide a creative and nurturing environment for children to engage in art-making experiences. These free classes allow youth to enjoy a variety of artistic media, interact with others, and build self-confidence.
We welcome all, and the day's program may include painting, drawing, Native American crafts, recyclable art, mixed media or drama. There is an emphasis on multicultural lessons, which demonstrates there are many different peoples who contribute to our world of art.
Classes are held in Studio 93 on Tuesdays and Thursdays 3:00 to 5:00 PM and Saturdays 10:00 AM to 12:00 PM. Ages 6 to 13 may attend.


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PVC Sprinkler Leak at T Joint
My PVC sprinkler system has a T joint at a certain point.
Water has begin to leak out of one of the ends of the T joint. There are no cracks in the pipe, it just leaks out of the T joint over the pipe going into the joint.
I tried putting some PVC glue/cement around that joint but the water still is breaking through.
Is there any way I can seal off this leak without replacing the T joint which would mean cutting apart three different pipe lines?
Is there some kind of combination of glue / cement and a certain tape that will keep the joint from leaking?
No, nothing short of replacing the joint will solve the leak, unless you believe the TV ads for some kind of miracle putty. However, there is an excellent fitting for only a couple of dollars. It is called an EZ span T. EZ span makes couplings that extend with an O-ring for replacing inline leaks. Simply push the ends toward the center about 1 1/2 inches (in a closed position if you will), measure how much you need to cut out of the damaged pipe then glue and extend the ends of the EZ span over the old pipe somewhat like an old fashioned radio antenna. A couple of years ago they came out with these Ts and they are a lifesaver for repairs at a T in the middle of a run.
BTW- they are only a couple of dollars, maybe three.
Sorry, don't know about an online source. Any plumbing supply near you should have one but might not find one at the big box stores.
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for Health Care Providers
Pulmonary Manifestations of HIV
Back to: Image Library | Pulmonary Images
Pneumocystis jiroveci (formerly carinii) pneumonia: chest X ray with bilateral, diffuse granular opacities
Chest radiograph of an HIV-infected patient, CD4 count of <200 cells/µL, revealing bilateral, diffuse granular opacities. This radiographic presentation is characteristic of Pneumocystis jiroveci pneumonia, which was microscopically confirmed by examination of induced sputum.
Laurence Huang, MD, University of California San Francisco
See related article in the HIV InSite Knowledge Base:
Pulmonary Manifestations of HIV


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Cadillac Escalade, EXT and ESV Forum - 2007-2014 Discussion, New Transmission Upgrade 07 Escalades in Cadillac Escalade Forums; I recently took my 07 escalade to the dealership for the 30,000 mil service. In addition to the 30,000 mil ...
- 04-01-09 12:42 PM #1Cadillac Owners Member
- Automobile(s): Cadillac
- Join Date
- Nov 2008
- Posts
- 8
New Transmission Upgrade 07 Escalades
I recently took my 07 escalade to the dealership for the 30,000 mil service. In addition to the 30,000 mil service i told them i was having trouble with the transmission. i.e. when i would put the car in drive or revers the car would jerk back and forth kinda. Also when i would stop at a red, there would be a thumping feeling. At first they blamed it on the oversize wheels, but after looking into it they told me that there is a transmission upgrade. they mentioned something about recalibration. If anyone is having the same problem take your car in and ask them to upgrade (re program) your trani system
Re: New Transmission Upgrade 07 Escalades
What they're likely refering to is a simple lubing of the tailshaft/yoke on the rear of the transmission. For whatever reason, GM is having a problem with this in 2007 at least, trucks/SUVs. They've got some super slippery lube they're putting on the transmission tailshaft to address this problem. What you're feeling is the yoke "suddenly" sliding in, giving the feeling of getting a good bump in the rear. It's very annoying...
- 04-02-09 09:18 AM #3Cadillac Owners 10000+ Posts
- Automobile(s): 2012 Escalade, 2014 SRX
- Join Date
- Apr 2003
- Location
- H.V., Pa/Town of Webb, NY
- Posts
- 13,307
Re: New Transmission Upgrade 07 Escalades
There was a software update for the trans soon after the 07's were released, several members that had problems with their transmissions had this done and saw improvement. Personally my two 07's could not have a better transmission, both shift strong on both upshifts and downshifts
- 05-15-09 07:56 PM #5Cadillac Owners Member
- Automobile(s): 2007 Escalade
- Join Date
- May 2009
- Posts
- 2
Re: New Transmission Upgrade 07 Escalades
I have a 07 Escalade that I purchased 5/06, I have had nothing but issues with the transmission. I first reported that there was a hesitation upon starting from a dead stop, "lag" at 40, rough shifting. All I hear is that the module controls the trans, they "tuned" module, took back, "tuned" module, took out the driveshaft and all of the other stuff but….this has gone on since I had truck. One time the transmission man said he had no idea what computer program was in the module, I tried to calmly explain that his dealership has done all of the work since I bought the truck from them. I get tired of bringing it in so I was just living with it until the other day when upon rapid acceleration the truck nosedived between shifts, this happened twice, and then developed a whining noise that gets louder until trans shifts and then starts again. Off to the dealership, service manger drove and heard noise, left vehicle, now there is no noise that they can find. The truck sits in the lot and they have no idea how to proceed…….thoughts?


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Luck-E-Strike Freak Deep Diver Crankbait
Sale price: Clearance price: Starting at: Sale starting at: Clearance starting at: Reg. price:
Designed by Elite Series Pro Rick Clunn, the Luck-E-Strike Freak Deep Diver Crankbait signals a drastic change to deep diving lures and the way they perform. Fitted with a square bill, the Freak deflects off cover in deep water as its shallow cousin does. However, a unique lip design gives the Freak a completely new water displacement signature that bass haven't seen or felt before. This lip design also allows the crankbait to maintain a very tight action that's not characteristic of other deep divers. While other deep divers feel mushy in really deep water, the Freak allows anglers to maintain contact. Another unique feature is this lure's flat tail which gives it a more natural appearance. After all, no baitfish has a round tail.
- Casts farther than other crankbaits
- Flat tail
- Square bill deflects lure off cover in deep water
- Unique lip design for a new water displacement signature
Need Help? 7 days a week: 7am to 10pm CT or call 1.800.227.7776 anytime


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Music plays a significant role in our lives. It brings us comfort, spurs us to action, keeps us company, and challenges the norm.
Unfortunately, just like any tool, music can be used for nefarious purposes.
I'm a sucker for a good love song (All of Me by John Legend, anyone?), but sometimes music is just another art form abused by a punk wanting to mouth off.
And then there are instances of sweet poetic justice where a dad fights back and it goes viral.
As the father of two little girls I am dreading the day boys start calling and knocking on the door. Mostly because I remember what I was like when the hormones kicked in.
I'm already praying for our daughters and working hard to set an example of what a good man/husband looks like.
It's difficult not to worry, but videos like this make me laugh and remember two things:
1. God is in control
2. I'm not afraid to fight dirty
P.S. You can follow the awesome dad who created this epic video right here on Twitter.
Build Your Digital Toolbox
Tired of trying to organize the chaos of work, life, and home? Get it sorted and remember everything with these tools.


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Welcome to Renniks Hire
Renniks Hire is your one stop shop for major events, festivals, large or small exhibitions, custom designed stands, conference, weddings and parties and are THE premier hire company in South Australia you can rely on!
Based in Adelaide, Renniks Hire can provide all of your temporary infrastructure requirements from the basic to the extravagant with pagodas, pavilions and marquees. There is a temporary solution for all of your needs.
In addition our product range includes flooring, indoor and outdoor furniture, catering equipment, crockery, cutlery, glassware, linen, lighting and more!
With the event and exhibition industry constantly changing along with tight and conflicting deadlines and budgets, our clients have come to rely on us year after year to ensure all phases of planning and implementation are smooth.
Renniks Hire offers complete event integration services providing you with a one stop shop for not only your on site venue exhibition or exhibition needs, but also your off-site gala dinner or welcome cocktail reception.
The team at Renniks Hire have the ability to manage your project efficiently, reliably and most importantly within your budget.
Subscribe to our newsletters
Renniks Hire have the best seats in town! Sign up here for all the news in the event and exhibition world!
When you subscribe you will also receive a $10 gift voucher for use on your next purchase.


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La. public school funding short $55M this year
BATON ROUGE - State lawmakers have learned that they face education financing gaps totaling $105 million over two years.
Superintendent of Education John White told the House Appropriations Committee on Tuesday that his department is $55 million short of what is needed to cover the costs of this year's public school funding formula.
White says more than half the shortfall is tied to having higher-than-estimated student enrollment at public schools. The rest of it he described as a "cash-flow issue" that he says Gov. Bobby Jindal's administration would explain.
No one from the governor's budget office immediately responded to the request for an explanation.
Meanwhile, White told the committee Jindal's budget is short $50 million of what's needed to cover the school financing plan submitted by the state education board for next year.
Image: WBRZ


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Comerica Quarterly Earnings and Conference Call April 17
19 Mar, 2012, 12:20 ET from Comerica Incorporated
DALLAS, March 19, 2012 /PRNewswire/ -- Comerica Incorporated (NYSE: CMA) will announce its first quarter 2012 earnings prior to the market opening on Tuesday, April 17, 2012.
(Logo: http://photos.prnewswire.com/prnh/20010807/CMALOGO)
Comerica will host a conference call to review first quarter 2012 financial results at 7 a.m. CT Tuesday, April 17, 2012. Interested parties may access the conference call by calling (800) 309-2262 or (706) 679-5261 (event ID No. 62064995). The call also will be accessible via Comerica's "Investor Relations" page at www.comerica.com. A telephone replay of the conference call will be available approximately two hours following the call through April 30, 2012. The conference call replay can be accessed by calling (855) 859-2056 or (404) 537-3406 (event ID No. 62064995). The replay also will be accessible via Comerica's "Investor Relations" page at www.comerica.com.
Comerica Incorporated is a financial services company headquartered in Dallas, Texas, and strategically aligned by three business segments: The Business Bank, The Retail Bank, and Wealth Management. Comerica focuses on relationships, and helping people and businesses be successful. In addition to Texas, Comerica Bank locations can be found in Arizona, California, Florida and Michigan, with select businesses operating in several other states, as well as in Canada and Mexico. Comerica reported total assets of $61 billion at December 31, 2011. To receive e-mail alerts of breaking Comerica news, go to http://www.comerica.com/newsalerts.
SOURCE Comerica Incorporated


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a great place for the killbillet community to meet each other and share ideas
If your thinking about joining the site you need to stop here first and read............
If your new here at KB tell us a bit about yourself......
Yesterday, 07:59 AM
The member directory is to help find members in your area and if you are in a pinch while traveling to find some help near by. Place your information in the state you live. Add any details that may help fellow members while traveling i.e. tools to use, space to crash (tent space), friendly place to stop by and say hi. Phone number optional, members can always contact you via PM.
Yesterday, 02:51 PM
There are currently 14 users browsing this forum. (0 members & 14 guests)


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When was 28 Painthorpe Lane WF4 built?
Asked on Feb 6 2011, General in Wakefield | Report content
Answers (1)
As long as the property is registered then you will be able to obtain a copy of the title deeds from your local Land Registry office or website. They will contain the date that the property was built.
Web reference: https://www.landregistry.gov.uk/wps/portal/Property_SearchAnswered on Sep 12 2011, Report content
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German Shepherd Dog Forums (http://www.germanshepherds.com/forum/)
- Breeding - General (http://www.germanshepherds.com/forum/breeding-general/)
- - Question for breeders about hand-washing (http://www.germanshepherds.com/forum/breeding-general/451674-question-breeders-about-hand-washing.html)
Question for breeders about hand-washing
Ok, I have two litters, one with 2 six week old pups, and one with 7 four week old pups. On Monday, I mowed the lawn and got sun-poisoning again -- you would think I would learn. Well, anyway, my hands are a mess.
And, I am washing them so much that they are cracked and bleeding all over. I wash them after I pick up puppies for whatever reason, and I wash them between dealing with the different litters, like, after I clean the one box, I will wash my hands and then go in and clean the other box, and then wash my hands. I feed them 4 times a day, and wash my hands before and in-between feeding each litter, and then when I am done.
And I will play with them when they are not eating, and then wash my hands.
Does anyone have any tips on what to do to promote healing for my hands. This is one thing where gloves are out of the question. But somethering my hands it lotions seems like a bad Idea as well.
Darn. No gloves or lotion. There went my ideas.
When I used to do that same thing (washing hands every 5 minutes all day) sometimes I would have to resort to either hydrocortisone lotion (at most twice a day for a couple days) or a liberal application of a good lotion (Neutragena's Norwegian Formula) and then into a pair of plastic gloves for the night.
Outside of that, maybe a moisturizing hand soap. Are you using an alcohol based hand sanitizer after washing? Those can dry skin out like crazy, and with proper hand washing technique they aren't necessary.
I wreck my hands at work, grease, dirt, welding heat, chemicals, multiple washing etc... They end up getting cracked, bleeding. Just use lotion a time or two before bed otherwise you'll just wash it off again. Usually works in a couple days for me.
Bag Balm from the feed store. Better than any lotion you can buy.
No alcohol based hand sanitizers. I use the bottle of reddish germ-killing stuff that they use on dogs, real common, the name will not come up. Starts with a b, I think. Or antibacterial dial soft soap in the bathroom, and dishwashing liquid in the kitchen. Just depends which direction I am going in next as to where my hands get washed.
I can apply lotion before bed, I will try that. I have some aveno stuff that seems pretty good. I do have sensitive skin anyway. I have also been accused of being a chronic hand washer by one of my doctors years ago, just hard on the skin. I am very careful to avoid unnecessary scented stuff in soaps, etc, anyway. And with the sun, well, I can't be outside for more than a few minutes without getting some reaction.
Out of curiosity, why no gloves?
quit the antibacterial soap. It's unnecessary & actually harmful as it builds more drug resistant bacteria. Also hard on your skin.
Use good quality lotion (Eucerin is one brand) or cream. Cheap or moderate lotion just isn't the same.
For soap my dermatologist said to use just basic dove bar soap. I have really bad eczema I ended up having to leave my job because the excessive washing where I had to wash my hands like three different times within a five minute period for eight hours or more. I was literally scratching chunks of skin off it was so bad by the time I ended up quitting.
For lotion before I was prescribed with Mometasone Furoate I used Aveeno Eczema lotion which was great but I also used Bag Balm.
I also used latex free nitrile gloves anytime I had to come in contact with water or something that would make me need to wash my hands excessively.
Good luck with the itching, cracking and bleeding hands :( I know it's a tough one to deal with.
During winter, my hands 99% of the time end up with cracks, sometimes bleeding. What has worked best for me anyway is vit e oil. I just poke a hole in the capsules, squeeze the oil out spread on my hands. I'll layer it sometimes with coconut oil, but have to watch out that the brats don't follow me around trying to lick the coconut off.
And yeah, the antibacterial soap .... is making your hands worse with the drying.
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Follow Harriet on Twitter
About Harriet
- The Poetry Foundation's blog for poetry and related news.
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- Archive
Poetry News
Call Heather Christle!
Heather Christle's new collection, The Trees The Trees, available from Octopus Books, just dropped, and while it's still hot you can call her, and she will read you a poem from said collection!
According to an article in The Guardian:
The American author, whose poems have appeared in the New Yorker, has just published her second collection, The Trees The Trees, and rather than relying on the usual publicity tour, has decided instead to list her phone number on her website. At set times every day until 14 July she will read a poem to anyone who calls her.
"The book itself is full of references to phones and phone calls, and the speaker often seems to mistake the technology of the page for that of the telephone, imagining that the reader is right there in the moment," said Christle. "My father is a merchant mariner, and when my sister and I were small we would record messages to him on cassette tapes. I'd often ask questions and then pause for his response. There's something so lovely and sad about the hope that another actual person is on the other end of any technology. So I thought it would be interesting to bring that dynamic forward, to read these poems (which frequently address a 'you') directly to another person, across the intimate distance a telephone creates."
So far she has received around 60 calls, from a multitude of different readers, from a couple from Toronto looking for a love poem to a class in western Massachusetts. "I've been amazed at how variously people respond. Some callers state quickly that they're calling for a poem, listen, say thank you, and then promptly hang up. Others want to chat a little bit about the project. I love it when people tell me where they're calling from. One man called on his break from work, which made me glow. If people seem chatty I'll often tell them where I am as well, because I think it's exciting to know that the poem they just heard was read in the middle of the shampoo aisle at the supermarket," Christle said.
"I didn't feel particularly anxious ahead of time. I trust poetry to make good things happen, and so far that's been the case. When I was writing these poems I so often had this mysterious 'you' just in front of me, just behind the page. When people call it's as if that imagined figure has suddenly come to life."
"This isn't the most terribly original idea," said Christle. "Another antecedent I should mention is the 'Dial-a-Poem' project, started by John Giorno in the late 60s, though that featured recordings, rather than live readings."
Speaking of John Giorno, let's get all intertextual up in this piece.
Are you scared to call her? Then you can at least hear her read here, but it probably won't be as fun.
Posted in Poetry News on Tuesday, July 5th, 2011 by Harriet Staff.


text: NEW YORK, April 3, 2014 /PRNewswire/ -- S&P Capital IQ announced today that it has commenced Standard & Poor's Factual Stock Report coverage on BioCorRx Inc. BioCorRx Inc. (OTCQB: BICX) offers a comprehensive and cost-effective recovery program for the treatment of alcoholism called the Start Fresh Program which the company believes incorporates all of the essential elements for successful alcohol addiction recovery. The Start Fresh Program is designed to treat and to heal both the mind and the body. The company's alcohol rehabilitation program is a two-part program that includes the insertion of a Naltrexone Implant, by a licensed medical physician, that is believed to reduce physical cravings of alcohol; and life coaching that focuses on the mental addiction of alcoholism. BioCorRx aims to make the Start Fresh Program the preeminent, long-term alcohol recovery program used by treatment centers around the world for alcoholics, as well as their family and friends. The Start Fresh Program is a comprehensive treatment program used by treatment centers that is designed to significantly reduce or virtually eliminate the physical cravings for alcohol by using the time-release implant of the drug, naltrexone. BioCorRx says that, with cravings out of the way, patients can address the psychological reasons for their alcohol abuse through the company's personalized Life Coaching Program. On March 4, 2014, BioCorRx announced the expansion of its Start Fresh Program to include treatment of opioid dependence. According to the company, naltrexone, the pharmaceutical component of the implant used by the Start Fresh Program, is FDA approved for the treatment of opioid addiction and has been used successfully for this purpose for many years all over the world. Treating this type of addiction varies however from the treatment of alcohol addiction, which is currently the main focus of the Start Fresh Program. Therefore, patients entering the new portion of the Start Fresh Program must meet certain criteria to qualify. On March 18, 2014, the company announced that it had entered into a letter of intent to sell the exclusive license and distribution rights for its Start Fresh Program in certain Midwestern states to Fresh Start Private Midwest, LLC (Midwest). Under the terms of the pending agreement, Midwest will agree to pay BioCorRx an upfront license fee plus an ongoing upfront fee per program order in the states of Minnesota, Missouri, and Oklahoma. The company was formerly known as Fresh Start Private Management Inc. and changed its name to BioCorRx Inc. in January 2014. BioCorRx Inc. is based in Santa Ana, California. S&P Capital IQ's Factual Stock Report coverage on BioCorRx Inc. will also be accessible on an ongoing basis to the investment community by scores of buy-side institutions and sell-side firms that utilize S&P Capital IQ research and information platforms daily. Millions of self-directed investors also have access to the report via their e-brokerage accounts. Please visit http://www.biocorrx.com for additional information. About S&P Capital IQ's Factual Stock ReportsCurrently profiling approximately 500 issuers, Standard & Poor's Factual Stock Reports, produced by S&P Capital IQ, increase market awareness of issuers in the investment community with insightful commentary and key statistics and information. Standard & Poor's Factual Stock Reports provide factual research coverage about company fundamentals and business prospects, thereby enabling information about covered companies to reach a wide investor audience of Buy and Sell-side investors. Updated weekly with the latest pricing, trading volume, and other data, the reports include recent developments, a financial review, key operating information, industry and peer comparisons, institutional holdings analysis, Street Consensus and opinions, performance charts, business summary, fundamental data, and news. Because coverage of these reports is underwritten by the issuer, S&P Capital IQ does not offer investment opinions concerning the advisability of investing in these stocks. Standard & Poor's Factual Stock Reports are produced separately from any other analytic activity of S&P Capital IQ or related organizations. S&P Capital IQ does not trade on its own account.


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Indybay FeatureRelated Categories: Palestine | International
Israel spurns UN call for monitors
Israel has rebuffed a UN call for an international monitoring force to be deployed in Lebanon as it continued to attack the country.
Kofi Annan, the UN secretary-general, had called earlier on Monday for a "cessation of hostilities" between Israel and Hezbollah to enable a well-armed international "stabilisation force" to be put together.
Speaking from the sidelines of the G8 summit in Russia, Annan had said: "We need to get the parties to agree as soon as practicable to a cessation of hostilities to give us time and space to work.
"I appeal to the parties to focus their targets narrowly and to bear in mind that they have an obligation under international humanitarian law to spare civilian lives [and] to spare civilian infrastructure."
Annan, who had earlier spoken to Tony Blair, the British prime minister, also said: "The sooner decisions are taken by the council, the better it is, but the parties need not wait for their full implementation to start the cessation of hostilities and to spare civilians."
But Israel, which has been attacking targets all over Lebanon in retaliation for missile attacks by Hezbollah, the armed Lebanese group which is also holding two Israeli soldiers, said it was too soon to consider such a proposal.
Miri Eisin, an Israeli government spokeswoman, said: "I don't think we're at that stage yet. We're at the stage where we want to be sure that Hezbollah is not deployed at our northern border."
Elsewhere at the summit in St Petersburg, the French president announced that he was to send his prime minister to meet the Lebanese prime minister in Beirut in a gesture of solidarity.
Monday Jul 17th, 2006 4:26 AM
British Prime Minister Tony Blair and United Nations Secretary-General Kofi Annan called Monday for the deployment of an international force in southern Lebanon, in order to end the spiraling conflict between Israel and Hezbollah.
But Israel reiterated Monday its opposition to the initiative. The Prime Minister's Office said Sunday night that Israel would not agree to the deployment of any troops in south Lebanon, save for the Lebanese army.
Israel is concerned that an international force would make it more difficult for the IDF to respond to future attacks from Lebanese territory.


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IC Holiday Shun Cheng Hostel
Room 2503, Building B, Shuncheng Superior Apartmen, Wuhua District, Kunming, China
- Air conditioning
- Free Wi-Fi
- Self-Catering Facilities
- 24 Hour Reception
- 24 Hour Security
- Airport Transfers
- Bar
- Bicycle Parking
- Breakfast Not Included
- Cable TV
- Cafe
- Common Room
- Currency Exchange
- Elevator
- Fitness Centre"
- Free City Maps
- Free Internet Access
- Hair Dryers
- Hot Showers
- Housekeeping
- Internet Access
- Jobs Board
- Key Card Access
- Laundry Facilities
- Linen Included
- Luggage Storage
- Meals available
- Meeting Room
- Mini Supermarket
- Nightclub
- Outdoor Terrace
- Parking
- Postal Service
- Reading Light
- Restaurant
- Shuttle Bus
- Tea/Coffee Making Facilities
- Telephone Fax Facilities
- Tours/Travel Desk
- Towels Included
- Washing machine
- Wheelchair Friendly
- WiFi
Check-in / Check-out
Earliest check-in: 14:00
Latest Check-out: 12:00
- Child Friendly
- Non Smoking
Group booking?
Group of 15 or more traveling to Kunming?
Private Rooms
Superior 2 Bed Apartment Ensuite
Sleeps 2
Room types
Private Room
Private Bathroom
Superior 2 Bed Apartment Ensuite
Sleeps 2
Room types
Private Room
Private Bathroom
Superior 6 Bed Apartment Ensuite
Sleeps 6
Room types
Private Room
Private Bathroom
Deluxe Double Bed Private Shared Bathroom
Sleeps 2
Room types
Private Room
Shared Bathroom
Superior 6 Bed Family Room Ensuite
Sleeps 6
Room types
Private Room
Private Bathroom
About IC Holiday Shun Cheng
IC Holiday Shun Cheng is conveniently located in the city center of Kunming with easy access to any place of the city. Downstairs is one of the biggest shopping malls in Kunming, Shun Cheng Shopping Mall. Lots of restaurants, coffee bars, clubs, shopping malls and banks are within 5 minutes' walking distance. Sightseeing within walking distance: Yunnan Provincial Museum, Flower & Bird Market, Zheng Yi Fang, Nanping Pedestrian Street, Jinma Biji Square and Green Lake.
All the apartments and rooms are fully furnished with 32-inch LED TV, washing machine, refrigerator, iron and hair dryer, etc. All the kitchens here are always in a usable state, you can cook by yourself if you don't want to go out for eating. Of course, the whole property is covered with free Wifi; broadband internet is accessible as well.
Here we also provide lots of extra services like car renting and tickets booking. Our English speaking staff is willing to provide you any information on daily life, travel or transportation.
Accommodation Information
---------- Conditions ----------
- Airport & Train Station pick up service upon request (10:00 - 22:00);
- Free telephone translation service;
- Car Renting, Travel booking and consulting;
- Iron & Hair Dryer;
- Laundry Service / Washing Machine;
- Kitchen with refrigerator and other cooking utensils;
- Gym;
- 24H Check-in (free late check-out upon request)
Location Information
- City center of Kunming, upstairs of Shun Cheng Shopping Mall;
- Within 5 minutes walking distance to lots of city sightseeings like Golden Horse Square, The Flower & Bird Market, The Muslim Street, Nanping Pedestrian Street and Zheng Yi Fang;
- Downstairs are supermarket, shopping mall, restaurants, coffee shops, banks and money exchange staion;
- Walking distance to Green Lake, Kundu Night Market, etc.
Cancellation Policy
Customers can cancel their reservation free of charge up to 1 day before arrival. After this date, charges will be applied by the property up to the first nights cost of the reservation, unless otherwise stated in the property's conditions. Deposits paid are non refundable.


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British Pound Declines Slightly As Dealers Assay U.S. Tax Call
In a relatively inactive day on London's foreign-exchange market yesterday the spot rate on the pound slipped slightly, closing at $2.7852. For the most part dealers appeared to be restrained in trading while attempting to assess the probable impact on the international market of President Johnson's call for a 10 per cent tax surcharge.
August 05, 1967
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Todd Stradford, Geography & Geology
|Home | Office Hours | Courses | Summer in Japan | Maps | UWP Home | Contact Me |
Student Success Center
|Mission Statement
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Career Center
To receive help with writing a resume, cover letter, or to find internship, co-op, and full-time career related employment opportunities, please call the Career Center at 608.342.1183 to schedule an appointment with a Career Consultant. The Career Center is located in Ullsvik Hall, Room 0200.
If you need assistance with test-taking strategies, managing your schedule, study tips, and/or finding ways to enhance your college experience, please contact the First Year Experience office in 120 Brigham Hall or via phone (342-1081) or e-mail (email@example.com).
For International Students
U.S. federal regulations state that all international students on an F-1 or J-1 visa must register and maintain a full-course of study (12 credits for undergraduates and 9 credits for graduate students) during the fall and spring semesters. Prior to dropping below full-time status, international students should consult the International Student & Scholar Services (ISSS) Office in Royce Hall (first floor) or call 608-342-1852 if they are experiencing difficulties maintaining a full-time course load. Visit www3.uwplatt.edu/isss for more information.
Karrmann Library
Your library provides free access to scholarly and peer-reviewed online and printed resources. Librarians are skilled in helping you critically evaluate materials, narrow the focus of your research, and find just what you need--within library walls and around the world. Visit our Web site at: www.uwplatt.edu/library
"If you need an accommodation due to a disability, please make an appointment to see me during my office hours. A VISA from Services for Students with Disabilities authorizing your accommodations will be needed. Contact 608-342-1818 for more information about SSWD."
Undergraduate research (including creative activity and scholarship) is an inquiry or investigation conducted by an undergraduate in collaboration with a faculty mentor to make an original intellectual contribution to the discipline. Visit or contact the Office of Undergraduate Research and Creative Endeavors at 515 Pioneer Tower or firstname.lastname@example.com for more information on research opportunities or URCE activities.
If you need tutoring for this class, contact Writing and Tutoring Resources (WATR) at 608.342.1615 or visit 314 Brigham Hall. Tutoring is either free (Writing Center) or the cost is minimal ($1.50/hr).
Materials for this course can be found in Desire2Learn. To access Desire2Learn, go to www.uwplatt.edu/Desire2learn. Click the Log In with NetID button and enter your username and password (the same that you use for email). Courses are arranged in order by semester. Scroll down the page to locate this course and click on the link. Course materials can be found by clicking on the Content link. If you need assistance with Desire2Learn, please contact the Helpdesk - 608.342.1400 or email email@example.com.
Religious Observances
"Students have the right to miss class for religious observances. Students wishing time off for this reason should let the instructor know within the first two days of class."


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Home > News & Events > News > Articles > The Institute of Politics Talks Millenials in the 2012 Election Cycle at the DNC
Youth vote advocates, media and public opinion experts gathered in Charlotte, NC to discuss the engagement and importance of younger voters in the 2012 election cycle at the Institute of Politics panel discussion prior to the Democratic National Convention's opening night.
IOP pollster John Della Volpe kicked off the Sept. 4 event underscoring that turnout by Millennials, 18 to 29-year-olds, was "incredibly important" to Barack Obama securing a presidential victory in 2008, particularly in battleground states like Virginia, Indiana and the 2012 Democratic National Convention host state of North Carolina.
However, Della Volpe also presented a summary of IOP spring 2012 polling data showing the ideological tide may be turning among this critical demographic group, revealing younger Millennials today – the group eligible to vote in their first Presidential election this fall – are significantly more conservative in their political ideology than older Millennials.
Among 18 to 19-year-olds, 42 percent self-identify as "conservative" with only 34 percent identifying as "liberal." At the other end of the Millennial age spectrum, those self-identifying as liberal outnumber those calling themselves conservative particularly among the 25 to 27-year-olds with 36 percent saying they are "liberal" and 32 percent "conservative." Among 28 to 29-year-olds 38 percent are "liberal" and 32 percent "conservative."
Moreover, Della Volpe showed Obama's margin over Republican presidential candidate Mitt Romney gets weaker among younger Millennials. While Obama's advantage over Romney is 16 percentage points among all 18 to 29-year-olds, his margin over Romney is twice as large among 25 to 29-year-olds, 23 percent, than seen among younger Millennials, 18 to 24-year-olds, 12 percent. Della Volpe asserted a key driver behind the numbers is younger Millennials coming of age within a political environment marked by an uncertain and struggling economy.
A panel discussion following Della Volpe's presentation focused on younger voters being increasingly "turned off" by today's politics – possibly leading to lower turnout among Millennials in 2012. The panel featured Della Volpe along with MTV News Correspondent Andrew Jencks, Campus Progress Director Anne Johnson, Rock the Vote President Heather Smith and panel moderator and IOP Director Trey Grayson.
Jenks discussed his experiences as an MTV News Correspondent travelling in battleground states around Super Tuesday and talking with Millennials who still "don't feel a part of the political process and don't know how to engage." During Smith's work in the younger voter advocacy world for the past 15 years, she agreed that young people feel disconnected from politics these days, but stressed, "We can't give up. We have to work harder. If we do the hard work, I believe they will show up in November."
Grayson underscored one of Della Volpe's key themes that millions of younger voters would be very interested in participating in the political process; they just need to be targeted, engaged and to be asked. "Our data shows that if you have a more receptive audience you can reach them more effectively," said Greyson.
The Institute produced a series of onsite events at the Republican and Democratic National Conventions as part of its Election 2012 programming.
Complete results from twelve years of IOP polling research on the political views of younger voters are available at www.iop.harvard.edu.
Pictured from L to R: Trey Grayson, director of the IOP; Anne Johnson, director of Campus Progress; Heather Smith, president of Rock the Vote; Andrew Jencks, MTV correspondent; and John Della Volpe, IOP director of polling.


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5 Wk VI Charter Wanted
My wife and I are experience sailors who have chartered directly from owners for about 4-5 years. We are looking for a 35-45'' modern monohull in the US or Brit VIs for a 5 wk charter beginning about mid Feb thru the end of March 2003. Also looking for a 3-4 stateroom cat (to accomodate family/kids) for either the week before or after our 5 wks on the monohull. Please respond off list to email@example.com
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text: Style Ionic Air System Hair Dryer | Remington Products $13.69 $27.99 + Free Shipping Remington Coupons See Deal About this Deal with code HC25 Flag this deal Edit deal What's the matter? Choose a reason Dead deal Duplicate Bad link Spam Inaccurate No value Alive again Comments (1) dropslike Sep 22, 2012 This dryer look very good. I have an old one you need to replace it. Reply Cancel Load More Comments


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Our reader is crazy about her guy but not sure where they stand despite nearly a year of dating. Let's help her out.
She writes:
From what you've said, things with this guy sound like they are great. But I have to wonder why then you are so afraid to ask him to define your relationship. It seems to me like there must be something making you doubt his feelings for you or his intentions toward your relationship if you are afraid having the Talk would ruin things. Pushing for commitment too early could be a bad move, but I think after nine months, you should both be ready to at least discuss it. I mean, your relationship could have had a baby by now.
So, if he really means that much to you, it's time to ask him what your relationship is. If it means you lose him, I know that will be very sad for you, but I'm not sure how much you'll really be losing. I know you care about him, but you seem to be missing some intimacy or maturity in your relationship if you can't talk about whether or not you're a couple. It's time to put your bond to the test and find out.
Best-case scenario: You'll ask him how he feels about the relationship and find out that he's on the same page as you and has just been feeling too nervous to ask. But if that's not the case, at least you'll know to move on to a relationship where you can feel free to discuss your feelings without being afraid to lose the guy. Wishing you luck!
Do you guys think nine months is too long to be dating without having the Talk? Relationships can move at their own pace, but I definitely think that's long enough to be comfortable getting serious! What's your advice for our reader?


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After Fireworks Party: Friday July 4 at Havana Club
The Havana Club
Friday, July 4, 2014 at 8:00 PM - Saturday, July 5, 2014 at 3:00 AM (EDT)
Who's Going
San Francisco, California
London, United Kingdom
Florence, Italy
Event Details
Come celebrate what America's all about, what our founding fathers have done for us, and the people who stand for it. Enjoy the festivities with us after the Lenox Mall fireworks show at Atlanta's premier night club. . Havana Club features 3 unique rooms with Live Djs & over 2000+ guests. Top 40 Room features Superstar DjRos, Gallery plays house music with London Thomas & Studio brings you latin music by Dj Harold. For table reservations & VIP specials contact us at email@example.com or call us at (404)-941-4847
When & Where
Havana Club
3112 Piedmont Rd NE
Friday, July 4, 2014 at 8:00 PM - Saturday, July 5, 2014 at 3:00 AM (EDT)
Add to my calendar
The Havana Club
Voted Best Nightclub in Atlanta
The breathtaking design of our luxurious venue captured the hearts of Atlanta's elite social groups on day one. The evolution of Havana Club began in 1996 with a humble yet popular cigar bar that withstood a miraculous transformation, developing the supreme nightclub destination you frequent today. Our venue fuses the appeal of an ultra exclusive lounge and a high-energy nightclub. We consist of three separate environments. Each individual room has plush VIP seating, a specific music genre, sensual lighting, custom sound systems, exclusive DJ's, & weekly themed events. The extraordinary design & ambiance of each room furthered our reputation of uniqueness amongst Atlanta's other leading venues. Havana Club was designed with your party in mind. With 15,000 square ft of space, our venue can comfortably accommodate large corporate/private parties. With our bungalow/cabana sections, we are perfect for your intimate gatherings. Each room is available for rent individually.
Hours Of Operation: Friday & Saturdays (8PM to 3AM)
Dress Code (Strictly Enforced): No sneakers/tennis shoes. No work boots. No flip flops. No shorts. No T-shirts. No athletic wear. No baggy clothing. No hats.
You are welcome to send all questionable clothing inquiries to our email.
Smoking is permitted.
Main Room:
Music: Top 40's (Current Hits)
Seating: Exclusive Stage Sofa, Premier VIP Sofas, Cabana/Bungalow Sections, Humidor area, Banquets
Our main room has hosted many of Atlanta's most successful holiday parties, corporate events, bachelorette parties, & themed events. It has been the permanent & temporary home to celebrity DJs worldwide. The humidor area is equipped with a full cigar bar stocked with your favorite brands.
The Gallery:
Music: House, Electronic, EDM
Seating: Premier VIP Sofas, High-tops
Our Gallery room will light up your world. From LED walls to lasers, we have one of the most prestigious lighting systems that this city has ever seen. This area is also fully equipped with a custom sound system built to produce high energy dance music with electrifying audio.
Latin Studio:
Music: Salsa, Merengue, Bachata
Seating: VIP sofa sections
Our latin studio is sure to heat things up! Offfering Salsa, Merengue, & Bachata music styles from 8PM until 3AM. Whether you're looking for a night of dancing, or a fun first date idea, our Latin Studio has everything you're looking for. VIP seating is also available in this room.
8:30pm to 3:00am
Alcohol: Full Bar
Smoking: Yes
Bar Style: Cigar, Dance, and Lounge
Audience: 21+
Atmosphere and Personality: Trendy
Features: Afterhours, Disc Jockey, Entertainment, Late Night, Live Performances, and Specialty Cocktails
Bar Style: Cigar, Dance, and Lounge


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Loren Shealy, a rising junior on the North Carolina field hockey team, has been named Sports Illustrated's College Athlete of the Year in recognition of her academic and athletic success.
"We're honored that Loren has been recognized this way," UNC Director of Athletics Bubba Cunningham said. "She's outstanding in all areas, truly an example of a student who is excelling at the highest levels both academically and athletically. We appreciate Sports Illustrated highlighting Loren as a representative of what's great about collegiate athletics and we're proud that she's a Tar Heel."
Shealy, who is from Charlotte, N.C., and attended Charlotte Country Day School, is majoring in business and is a member of the prestigious Robertson Scholars program, through which she attends Duke in addition to UNC.
She ranked second in goals for the 2012 Tar Heels, who won their second consecutive Atlantic Coast Conference title and reached field hockey's NCAA Championship game for the fourth year in a row. At the championship, Shealy received the NCAA Elite 89 Award as the player at the final four site with the highest GPA. Shealy was named to the ACC All-Tournament Team as well as the All-ACC Academic Team.
"I'm thrilled to see Loren honored with this award," UNC head field hockey coach Karen Shelton said. "She's an outstanding representative of our program and our University. While she's very intelligent and athletically gifted, she also works so hard to be successful and maximize her potential and it's great to see that recognized. We're all so happy for her and congratulate Loren, as well as her parents, on this honor."


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Algorithm Research Paper
Posted On November 9th, 2007 | Research Paper Writing
Algorithm research papers are commonly assigned to students engaged in studying mathematics, computing, linguistics and related disciplines. The problem of algorithm was firstly analyzed in 1928 by David Hilbert; algorithm was defined as a cohesive unity of subsequent procedures which serves to solve some mathematical problem. Nowadays the spheres of the tasks algorithms are intended to solve cover more problems than simply that of mathematics. Each issue which needs to be investigated as a unity of the instructions to keep to for reaching the necessary results may become the subject of algorithm research paper.
For example, you may be signed to write an algorithm research paper on computing. In this case you are most likely to investigate the use of specific programming language; you will analyze the basic principles of composing algorithms which will lead to a highly organized computer program. If you are assigned to write an algorithm research paper on mathematics you will deal with doing some sums, solving of which is impossible without the implementation of the algorithm.
Our advice before indulging into writing algorithm research papers is to study the essence of the algorithm. Various manuals and researches on algorithm may turn useful for understanding the way algorithm works and realizing its functions in the process of solving the problems.
The next thing you should do while writing an algorithm research paper is to consult the professor about his/her requirements to your work, as they will be the burning aspect attracting the professor's attention.
While doing the research on your algorithm research paper we warn you to be concrete and precise: arrange the data gathered in the way the most appropriate to you, write out the needed information about the sources used to facilitate the work when writing entries for your algorithm research paper bibliography.
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The 10 Mistakes First-Time Homebuyers Make
Buying your first home is an intimidating enterprise. If you're thinking about taking the plunge, then check our list of what not to do.
1 Not Getting Qualified for a Mortgage First
YinYang/Getty Images
2 Buying With Your Heart—Not Your Head
Martin Barraud/Getty Images
3 Doing Due Diligence on the Neighborhood
mcdc/Getty Images
4 Not Understanding Closing Costs
Rob Daly/Getty Images
5 Not Having Cash on Hand for Unexpected Expenses
tazytaz/Getty Images
6 Forgetting About Operational Costs
Mint Images/ Tim Pannell/Getty Images
7 Skipping the Home Inspection
Imagesbybarbara/Getty Images
8 Not Using a Buyer's Agent
PhotoAlto/Eric Audras/Getty Images
9 Diving Into Remodeling
peepo/Getty Images
10 Hoping to Cash In
Fuse/Getty Images


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Zinc and BDNF
Byron's Comments:
The important role of zinc in nerve health.
Study Title:Antidepressant-like activity of zinc: further behavioral and molecular evidence.
Study Abstract:
Zinc exhibits antidepressant-like activity in preclinical tests (the forced swim test and tail suspension test) and in olfactory bulbectomy and chronic unpredictable stress; two models of depression. Zinc also enhances the treatment of depression in humans. In the present study we evaluated the antidepressant activity of zinc in another model of depression-chronic mild stress (CMS) and the effect of zinc treatment on BDNF protein and the mRNA level. In CMS zinc hydroaspartate (10 mg/kg) exhibited a rapid (after 1 week of treatment) antidepressant-like effect. Chronic treatment with zinc induced a 17-39% increase in the BDNF mRNA and protein level in the hippocampus. These data indicate a rapidly acting antidepressant-like activity of zinc in CMS and the involvement of zinc in the regulation of BDNF.
Study Information:
Sowa-Kućma M, Legutko B, Szewczyk B, Novak K, Znojek P, Poleszak E, Papp M, Pilc A, Nowak G. Antidepressant-like activity of zinc: further behavioral and molecular evidence. J Neural Transm. 2008 September Epub ahead of print.
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