text:
Tony-winning Broadway great Marian Seldes dies at 86
NEW YORK (Reuters) - Tony-winning actress Marian Seldes, regarded as one of the great ladies of the American stage and famed for never missing a single performance during an entire four-year Broadway run of "Deathtrap," died her Manhattan home on Monday at age 86.
Her death, which followed a prolonged illness, was announced by her brother, Timothy Seldes, in a statement issued through a longtime publicist, Sam Rudy.
In a career spanning six decades, Seldes performed in film, television and radio but was most celebrated for her theater work, making her Broadway debut in 1948 in the Robinson Jeffers adaptation of "Medea," directed by John Gielgud and starring Judith Anderson in the title role.
Seldes earned five Tony nominations, winning the award her first time out in 1967 for her supporting role in "A Delicate Balance" by the playwright Edward Albee, with whom she had a long association. She also appeared in productions of Albee's "The Play About the Baby," "Tiny Alice," "Counting the Ways" and "Three Tall Women."
She received a Tony Lifetime Achievement Award in 2010 honoring her contribution to the theater. Taking the stage to accept the accolade, she famously placed her hand over her heart, gazed out at the audience of stage luminaries and exited without uttering a word.
She later explained, "They said to keep it short, so I decided I would just say nothing."
Seldes' influence on American theater and the world of entertainment at large extended to her work as a renowned acting teacher at the Juilliard School, and later as an adjunct professor at Fordham University.
Among her better-known students were such stars as Kevin Kline, Laura Linney, William Hurt, Kelsey Grammer, Christopher Reeve, Kevin Spacey, Patti Lupone, Viola Davis and Robin Williams.
Born and raised in Manhattan, Seldes secured a place in the Guinness World Records book, and in Broadway lore, for appearing in Ira Levin's "Deathtrap" from 1978 until late 1982 without missing a single show. Continued...


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SCCR34: Atmospherics of WIPO negotiations on a broadcasting treatySubmitted by thiru on 1. May 2017 - 3:28
Currently, the WIPO Standing Committee on Copyright and Related Rights (SCCR) is engaged in negotiations on a Treaty for the Protection of Broadcasting Organizations, an exercise dating back to 1998. (Source: Timeline of WIPO negotiations on a Treaty for the Protection of Broadcasting Organizations).
WIPO SCCR 34 May 1, 2017 Day 1: Agenda and Election of New Chair and Vice ChairsSubmitted by Manon Ress on 1. May 2017 - 2:40
The DG, Franci Gurry, started the SCCR meeting with a summary of the issues to be discussed, some old (Broadcasting treaty, Limitations and Exceptions for libraries, archives, museum and education and for people with other disabilities) some new or "exploratory" (GRULAC proposal on copyright and digital works and resale rights):
How Sanofi Prices Its MS Drug Aubagio (Teriflunomide) in the U.S. and Five Reference CountriesSubmitted by Zack Struver on 28. April 2017 - 12:31
The U.S. Army recently rejected requests by public interest groups, Senator Bernie Sanders, and almost a dozen House Democrats to refuse to grant Sanofi an exclusive license on patents on a Zika virus vaccine, or, alternatively, to ensure that the license included terms assuring that U.S. taxpayers would not pay a higher price than other high-income countries. Specifically, KEI proposed the following terms to be included in the contract:
U.S. Army Rejects Pricing Concerns in Grant of Exclusive Patent License to Sanofi on Zika VaccineSubmitted by KEI Staff on 24. April 2017 - 11:41
Today, KEI received a letter from the U.S. Army dated April 21, 2017, signed by Barry M. Datlof, in which the Army largely rejected concerns raised in comments submitted by KEI and various other public interest groups related to the proposed grant of an exclusive license to the French drug company Sanofi on a U.S. Army-invented vaccine for Zika virus.
2017: KEI, UACT Request that Trump Administration Reevaluate Xtandi PetitionSubmitted by Andrew Goldman on 19. April 2017 - 10:55
Knowledge Ecology International and the Union for Affordable Cancer Treatment sent a letter to Secretary Tom Price of the Department of Health and Human Services, and to Secretary Jim Mattis of the Department of Defense, requesting that the Trump Administration reevaluate the January 2016 Xtandi petition that the government use its rights in patents under the Bayh Dole Act (35 U.S.C.
KEI Statement on House Letter to President Trump on the Protection of Taxpayers' Rights in Federally-Funded InventionsSubmitted by Zack Struver on 4. April 2017 - 10:26
CONTACT: Zack Struver, email@example.com or +1 (202) 332-2670
In a letter sent today, Representative Lloyd Doggett, D-Texas, and 50 other democratic members of Congress requested that President Donald J. Trump issue guidance for the use of Bayh-Dole Act march-in rights in order to protect taxpayer's rights in federally-funded patented inventions.
The following statement should be attributed to James Love, Director of Knowledge Ecology International (KEI):
"The letter from members of Congress on the need to protect taxpayer's rights in the inventions they fund is important, timely, and directly related to the challenge of providing affordable health care to everyone. Federally-funded inventions are now routinely placed on the market at extremely high prices. Astellas charges more than $350 per day for the prostate cancer drug Xtandi, and BioGen is charging $1.125 million for the first two years of Spinraza, which is used to treat spinal muscular atrophy in mostly young children. The notion that the federal government will not engage on the pricing of these products runs counter to the explicit provisions in the Bayh-Dole Act that require inventions be made 'available to the public on reasonable terms.' The President can curb high prices for these drugs without new legislation, and without putting patients at risk."
KEI filed the most recent march-in request with the federal government on the prostate cancer drug Xtandi.
The letter is available as a PDF here and below in plain text.
Representative Doggett's office issued the following press release: https://doggett.house.gov/media-center/press-releases/congressional-democrats-trump-we-re-calling-your-hand-lower-prescription
Democrats in House and Senate introduce new drug pricing billSubmitted by James Love on 29. March 2017 - 16:18
The House version is HR 1776. Attached below. The Senate bill is identical, and also attached.
Senator Franken's press release is here.
Representative Schakowksy's press release is here:
Senator Franken's facebook statement is here.
KEI statement: 21st meeting of the WHO Expert Committee on the Selection and Use of Essential MedicinesSubmitted by thiru on 27. March 2017 - 6:17
On Monday, 27 March 2017, Knowledge Ecology International (KEI) delivered the following oral statement to the Open Session of the 21st Meeting of the WHO Expert Committee on the Selection and Use of Essential Medicines. The program for the open session can be found here.
Dr. Elias Zerhouni defends Sanofi/Army proposed license on Zika patents, and KEI respondsSubmitted by James Love on 22. March 2017 - 7:42
On March 21, 2017, the New York Times published a letter signed by Dr. Elias Zerhouni, defending the proposed Sanofi monopoly on the US Army patents to the Zika virus. The letter is available from the NYT from the following link, and also reprinted here, followed by commentary.
To the Editor:
Re "Trump Should Avoid a Bad Zika Deal" (Op-Ed, March 11):
Maryland House of Delegates passes bill on prescription drug price gouging by vote of 137 to 4Submitted by James Love on 21. March 2017 - 12:24
On March 20, 2017, the Maryland House of Delegates approved a prescription drug price gouging bill by a vote of 137-4. A copy of the bill, as it passed the House, is attached.
This is a March 20, 2017 Report by Erin Cox, published in the Baltimore Sun:
Maryland's attorney general could sue drug companies for price gouging under a bill approved by the House of Delegates Monday.
Leaked document: March 15, 2017 Note by Switzerland on India EFTA TEPA IP ChapterSubmitted by James Love on 21. March 2017 - 9:35
Attached is a March 15, 2017 note by Switzerland on the India EFTA TEPA IP Chapter.
The EFTA is the The European Free Trade Association. The EFTA member states are Iceland, Liechtenstein, Norway and Switzerland. The document refers to a proposed "Trade and Economic Partnership Agreement," or TEPA, between India and the four members of the EFTA. The EFTA page on this negotiation is here.
Patients, Members of Congress Ask Chilean Government to Issue Compulsory Licenses on Prostate Cancer and HCV Drug PatentsSubmitted by Zack Struver on 21. March 2017 - 7:13
CONTACT: Zack Struver, email@example.com, +1 (202) 332-2670 (office) / +1 (914) 582-1428 (cell)
Luis Villarroel, firstname.lastname@example.com, +56 9 9827 9673
Santiago, Chile — Members of the Chilean Congress and a group of 6 patients visited the Chilean Ministry of Health yesterday to ask that the government use its authority under Chilean law to end patent monopolies on the prostate cancer drug enzalutamide (U.S. brand name Xtandi) and on sofosbuvir-based combination drugs for the treatment of hepatitis C virus (HCV).
The patients and members submitted a petition that outlined the legal authority and public policy rationale for the grant of compulsory licenses on the patents for the drugs described in the petition. Those compulsory licenses would allow prescription drug manufacturers to produce affordable generic versions of the drugs, subject to a reasonable royalty.
Leaked: Three documents from RCEP negotiationsSubmitted by James Love on 21. March 2017 - 6:56
The Regional Comprehensive Economic Partnership (RCEP) is a proposed trade agreement involving 16 countries in the Asia/Pacific region, that have a combined population of 3.5 billion persons, and about 30 percent of world GDP. They include the members of the Association of Southeast Asian Nations (ASEAN) (Brunei, Cambodia, Indonesia, Laos, Malaysia, Myanmar, the Philippines, Singapore, Thailand, Vietnam), and six additional countries: Australia, China, India, Japan, South Korea and New Zealand.
14 March 2017 - Senate Finance Committee grills Robert Lighthizer (USTR nominee) on trade and IPR policiesSubmitted by thiru on 20. March 2017 - 3:39
On 14 March 2017, the U.S. Senate Finance Committee held confirmation hearings for Robert Lighthizer, President Donald Trump's appointee for United States Trade Representative. During the Reagan administration, Lighthizer served as Deputy US Trade Representative with the rank of Ambassador (Source: http://www.presidency.ucsb.edu/ws/?pid=41174). Prior to his tenure as Deputy USTR, from 1981 to 1983, Lighthizer served as Chief Counsel for the U.S. Senate Finance Committee. Currently, he is a partner at Skadden Arps.
KEI Testifies in Maryland on Drug R&D Cost Transparency Bill (HB666/SB437)Submitted by Zack Struver on 16. March 2017 - 15:01
James Love and Andrew Goldman represented KEI on March 16, 2017, in a working group meeting of a subcommittee of the Maryland General Assembly House of Delegates Health & Government Operations Committee, where they testified on HB666/SB437, a bill that would establish transparency of R&D costs for prescription drugs sold in Maryland.
Vincent DeMarco of at Health Care for All! and Dr. Reshma Ramachandran of the Johns Hopkins Bloomberg School of Public Health also testified at the hearing.

subset: commoncrawl


text:
Brick Township Offering Amnesty for Work Done without Permits
Brick Township residents who did work to their properties before or after super storm Sandy without permits will get a chance to file the proper paper work without being penalized.
Mayor John Ducey and the Township Council are offering an amnesty program the entire month of June. "The amnesty period is for one-month only, from June 1 to June 30. As soon as July 1 comes, then penalties can be assessed up to $2,000," said Ducey.
The amnesty excludes commercial properties Ducey said, "It's for all residential zones R-3 and R-5, which are the homes, the apartments, the rentals, single family condos."
Ducey said some people may not have realized they needed permits for work done and noted the amnesty program is for safety purposes. "What it really does is really promote safety. We want to make sure the people who did the work, who live in those homes are safe, but not only those people, but obviously their neighbors as well are safe. A lot of different electrical type work has been done and we don't want to see a rash of fires due to it not being done properly," he said.
Residents can go to Town Hall, 401 Chambersbridge Road, during normal business hours Monday through Friday, between 8:30 a.m and 4:30 p.m. the entire month of June to apply for permits without being penalized. Inspectors will be sent to the properties once the paper work is filed.
"Also, on June 17, I'm having one of my Mayors In Nights and it's going to actually be located down in the Building Department. And we're going to have the entire Building Department Staff there. That starts at 6 p.m. and will continue until the last person leaves," Ducey said. "And what that does, it gives people an opportunity. They don't have to take a day off to come in for permits. They can come after-hours and be able to do all the work they have to do without having to miss any of their own work."


text:
Price: $56500
.Befour TFPS (also known as the PS-6600 ST) is the 'gold standard' of wrestling scales and the 2010 edition is the best ever, now with push-button calibration.
Price: $57500
.The TFPS57 is designed for maximum portability. It features the same capacity, accuracy and famous Befour quality, but with alkaline battery power, so there is no outlet or re-charging needed. TFPS57 has 13' x 13' platform,
Price: $61500
.The TFPS67 is designed for maximum portability. It features the same capacity, accuracy and famous Befour quality, but with alkaline battery power, so there is no outlet or re-charging needed. -TFPS67 has the 16' x 18' ST platform
Price: $77500
.Accurate And Versatile, the newest digital tabletop Scoreboard Timer Easy to OperateFour Period IndicatorIndividual Scoring ControlsBright 4 LED Numerals for Score and TimeCounts Down from Your Pre-Set TimeLoud Horn Sounds when time expiresSolid State CircuitryConvenient Carry handleUsuable for Multiple SportsProgrammable Training ModeManufactured in the U.S.A.Two-Year WarrantyTotal Weight - 22 lbsScoreboard Size - 33 x 8 x 2Console size - 7 x 6 x 5
Price: $2,75900
.Designed for true 360° visibility, this 3-sided tournament scoreboard has more helpful features, user-friendly controls, and a durable design that ensures years of trouble-free service. Operating the it is so easy that even untrained scorekeepers can master it within minutes; the control layout is simple and logical.
Price: $9299
.• Custom-designed for the BEFOUR scales • Safely stores scale platform, readout console, and cables • Great for storage, protection, and transport
Price: $24999
. • Durable hard-shell carry case for added protection • Interior foam securely holds the PS-6600 in place • Lock and keys included
Price: $24999
.HARD SCALE CASE for the Befour #TFPS57 & TFPS67


text:
"Is exactly as described. The quality of the paper and printing is very good. It made our giveaways look even more polished and sophisticated. It's simple, chic, and modern."
"nice & modern. this was hip and trendy without going overboard. The colors printed nicely. I chose the blue. Definately recommend!"
"As I am the type to either remember to buy a gift OR a card these easy, yet fabulous, sticker gift labels are perfect for when it's a gift! I love them!"
"These little labels are so festive. I had them printed with just my daughter's name so I can use them in books, personal belongings and also as gift tags. The color and quality are superb as with every Tiny Prints order. A great value and it's wonderful how many uses you can come up with for these little labels!"
"I ordered these stickers on a whim. I ended up using them on the birthday favors! Everyone got a bottle of wine wrapped up in foil, tied up with ribbon and I put a sticker on each one!!! It was PERFECT!!!! Everyone raved how creative I was!!"
Copyright © 2004-2017 Shutterfly, Inc | Tiny Prints | Terms of Use. Designated trademarks and brands are the property of their respective owners.


text:
Zannichellia palustris
Horned pondweed is a bay grass with long, thread-like leaves and distinctive horned seeds in spring. It grows in fresh and medium-salinity tidal waters of the Chesapeake Bay and its rivers.
Horned pondweed is made up of long, thread-like leaves that taper to a point at the tips. Leaves can be up to 3 inches long and grow opposite or in whorls along slender, branching stems. In spring, slightly curved seeds with tiny horns grow in groups of 2 to 4 at the leaf axil. Horned pondweed has thin rhizomes and short, tendril-like roots. It grows in two forms: an upright form with free-floating branches, and a creeping form with roots that anchor the plant to the bottom. The second form is common in winter and in areas with lots of waves.
Grows in low- to medium-salinity tidal waters. Generally found in shallow waters, but can grow to depths of 16 feet. Able to grow in both muddy and sandy sediments. Dies back in early summer when water temperatures warm.
Found throughout the upper and middle Chesapeake Bay and its rivers.
Migratory waterfowl feed on the plant and its seeds.
Horned pondweed only reproduces sexually. Seeds form in the spring and are released into the water by June. After releasing their seeds, the plants die back. Seeds generally germinate during the same year. This cycle may repeat itself in autumn if horned pondweed grows back after water temperatures cool.
Click tabs to swap between type and habitat.


text: Retail Black Friday 2015: A Big Deal for Online Retailers? 26th November, 2015 Black Friday has become one of the biggest shopping days of the year and, for anyone living on another planet, it's with us again this week. A few years ago, the discounts and deals day was little more than an American marketing ploy … Read more Sarah Furbank Senior content marketing specialist


text:
- log in
- account
A new Rung on the Social Technographics Ladder
Posted by Emily Riley on January 19, 2010
- 726 Recommendations
- 2 comments
We are bringing the Social Technographics ladder into 2010 with a new rung called "Conversationalists" to represent the very active communication style that has arisen recently within social media platforms like Twitter and Facebook.
Many months ago, several of us at Forrester started monitoring these emerging behaviors and mulling over how to represent them appropriately. We toyed with adding tweets and status updates to the "Creator" activities, but that would overshadow the more measured content contributions of bloggers and viral video creators. We thought of adding themto "Joiner" behavior, but that masked the fact that this wasn't about being part of a social graph, but rather communicating within the graph in a new and important way.
The beauty of the ladder is in its simplicity: the bottom represents the most passive social media participation, and types of participation increase as you go up, with "Creators" at the top. Now we will place "Conversationalists" between Creators and Critics. Deciding to change it wasn't easy; It's proven to be so valuable at showing growth in various social behaviors that we haven't needed to change it, until now. Today, we have a new ladder that keeps the best of the original, but adds to it new important behaviors for Interactive Marketers to learn about.
There are three key reasons for Interactive Marketers to care about Conversationalists:
- 33 % of adults are Conversationalists. In other words, they represent one third of your online target audience.
- By following Conversationalists, you get free consumer insights. Conversationalists are your customers and they are talking about you. Listen to them!
- By communicating with Conversationalists, you embrace change. Interacting with your customers in an ongoing way, in a conversation, creates lasting learning on both sides.
The purpose of the ladder is to provide consumer behavior insight to Interactive Marketers, so we reserve the right to alter it to fulfill this purpose. If you have thoughts about the new rung, or other behaviors emerging on the social landscape, let us know!
To see the entire ladder, and get more insight, check out the report here.
re: A new Rung on the Social Technographics Ladder
Comment from Alexis Ceule (not verified) on Wed, 01/20/2010 - 11:46
Emily, I think "conversationalist" is dead on! Brilliant. I am going to be watching anxiously to see how this plays out for you. I see it fitting in just right. Keep us posted!
re: A new Rung on the Social Technographics Ladder
Comment from null on Wed, 01/20/2010 - 22:12
Will you be updating the tool on the Groundswell page with the new category?
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text:
2. Angle eyes fixed.
whats the matter with the angel eyes?
2. Angle eyes fixed.
whats the matter with the angel eyes?
Thanks for all the help guys...
Right.. after reading around and getting anooied I just said F it and just brought these POWERFLEX REAR TRAILING ARM BUSH BMW E36 3 SERIES + M3 | eBay as lots of people say you dont need special tools to fit!
They were on the car when I got it but had a look this evening and abit of a play.. the bulbs look ok.. not sure how to test the rings but Im guessing it might be the inverters, so Ive just brought 2 of these aswell! lol.
Is it probably them?
They were on the car when I got it but had a look this evening and abit of a play.. the bulbs look ok.. not sure how to test the rings but Im guessing it might be the inverters, so Ive just brought 2 of these aswell! lol.
Is it probably them?[/QUOTE]
could be.could always try a battery on them do double check or maybe loose wires going in the sidelight plugs
You will have to drill and cut the old bush out still as you don't have the tool to remove the trailing arm bush. They take no longer than 1/2 a hour with the tool.
Ok firstly, Angle Eyes are fixed :-) ... Replaced the inverter's last night and now they are fine!
Secondly.. Whilst at It i decided to have a quick look at what I was up against on this bush and took the back wheel off. Now, to be honest I couldnt really find what I should be looking at! When the chap at the garage ramped it up, he showed me it and it was clear and easy to see.. also, from memory, the bush looked to be white.
Now this is a picture of the only thing I could find that looks like a bush and it does look and feel like the rubber inside is flaky and dead.. but im sure this isnt what I saw in the shop!.... Is this the right thing???
Also... its the first time I'd of done it.. where in particular should I put the car stands underneath? what hard point should I put them under? Im gunna just take both wheels off and put the whole back end in the air (chocking the front obviously xD)
Yes that bush is knackered, the arm shouldn't be touching the side like that, you can see in the picture the bush is pulled out.
Richy--Roo (27-02-2012)
Phew... Ok.. Thanks Ronnie... Now I know where It is and looking at various guides I can match up bits and feeling abit more confident about it now!
Try my mechanic mate, known him ten years or so, top bloke.
Kev muddyman owns a garage called prestige in eling totton,
I drop my car off the night before, he gives me a loan car for the night then I pick mine up the next day work all done.
His number 02380 667819 or 07831573957 hope this helps.
Spirit (29-02-2012)
So, Ive been reading around on here alot last couple days... And Ive seen a few threads about faulty Rear Shock Mounts.. and the symptoms of this being rear banging when over potholes and bumps.. and this is pretty much my exact issue.
Are the chances its this causes the main issue instead of the bushes?
Really annoying if so.. Wont be able to get any delivered in time for this weekend when I'm hoping to do all the work :(
Well, that was a complete and utter failure if ever Ive seen one!
Got the Trailing Arm down and bits..
The bush that was in there.. the inner rubbery bit basically fell out with a quick push on the flathead screwdriver but only on a closer look and seeing that the new bushes wouldnt fit it..
That metal bit around the edge in the photo was still in the arm.. it looks like its been in there so long that its basically fused to the arm itself..
No matter how much banging, drilling, wedging I tried it just wasnt going anywhere! :@ :@
In the end (getting dark) Ive had to just slot the old bush back into place and leave it like that...
Gunna HAVE to get some garage to do it! :@ :(
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News About Golden Rose Odds
2016 Golden Rose Betting Update: Omei Sword Back Up Top
The Golden Rose Stakes 2016 betting markets for this afternoon' feature at Rosehill Gardens remain a battle for favouritism between Astern and Omei Sword with the latter regaining top spot in the odds.
Chris Waller's last start Silver Shadow Stakes winning filly Omei ...
Golden Rose Stakes 2016 Tips & Odds Update
The 2016 Golden Rose Stakes runs at Rosehill Gardens on Saturday, betting tips and the latest odds on the three-years-old classic detailed below.
Running as Rosehill Race 6 at 3:10pm (AEST), this year's $1 million Group 1 ...
2016 Golden Rose Form Guide & Betting Preview
A line-up of the season's best three-year-olds face off in the Golden Rose 2016 in Sydney on Saturday, a comprehensive form guide analysis and betting update for the Rosehill Gardens classic found below.
Due to run as Rosehill Race 6 at 3:10pm (AEST) ...
2016 Golden Rose Betting: Omei Sword New Favourite
Despite the poor overall record of fillies in the race the bookmakers are taking no chances with the Chris Waller-trained Omei Sword installing her as the new Golden Rose Stakes 2016 betting favourite for this weekend.
The ...
Rain Could Wash Good Standing Out of Golden Rose Stakes
James Cummings will resort to a Listed Melbourne run at Flemington this Saturday if the rain comes down in Sydney ruining the top three chances of his colt Good Standing in the 2016 Golden Rose Stakes.
Fourteen ...
Bowman Chases 5th Golden Rose win on El Divino
One of Sydney's champion jockeys Hugh Bowman gets a chance at a fifth Golden Rose Stakes winning ride this weekend jumping aboard the Gai Waterhouse & Adrian Bott-trained El Divino in the classic.
A below-capacity field ...
Street Smart Derryn Raids Golden Rose Field 2016
The sole Victorian visitor in the 2016 Golden Rose Stakes field this weekend in Sydney is the Lindsay Park-trained Derryn who co-trainer Tom Dabernig as described as being more "street smart" than his earlier runs.
Berry Lets Hawkes Choose 2016 Golden Rose Stakes Ride
Ace Sydney hoop Tommy Berry will let the Hawkes Racing stable choose which of their two top Golden Rose Stakes 2016 hopefuls he will partner in Saturday week's Rosehill Gardens classic.
Blinkers on Yankee Rose in Golden Rose 2016
The now Queensland-based David Vandyke is expected to add blinkers to the gear of 2016 Golden Rose hope Yankee Rose in Saturday week's Group 1 to try and bring the best form out of the filly.
Astern Leads Updated 2016 Golden Rose Odds
A smart win in the Run To The Rose last Saturday has pushed the John O'Shea-trained Astern to the top of the pre-field Golden Rose Stakes 2016 odds for Saturday week's Group 1 classic in Sydney.
Over the weekend jockey James McDonald guided the ...


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Efficacy and Safety of BMS-690514 in Combination With Letrozole to Treat Metastatic Breast Cancer
This study has been completed.
Bristol-Myers Squibb
Information provided by (Responsible Party):
Bristol-Myers Squibb
ClinicalTrials.gov Identifier:
First received: February 12, 2010
Last updated: September 23, 2015
Last verified: September 2015
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
The purpose of this study is to determine if BMS-690514 + letrozole will be more effective than lapatinib + letrozole in patients who have metastatic hormone receptor positive breast cancer after developing progressive disease immediately following adjuvant antiendocrine therapy
|Breast Cancer
|Drug: BMS-690514 Drug: Lapatinib Drug: Letrozole
|Phase 2
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|An Open-Label Randomized, Parallel, Two-Arm Phase II Study Comparing BMS-690514 + Letrozole With Lapatinib + Letrozole in Recurrent and Metastatic Breast Cancer Patients Who Are Hormone Receptor Positive Despite HER2 Status And Who Relapsed While Receiving or After Completing Adjuvant Antiendocrine Therapy
Resource links provided by NLM:
Genetics Home Reference related topics: breast cancer
MedlinePlus related topics: Breast Cancer
Drug Information available for: Letrozole Lapatinib Lapatinib DitosylateU.S. FDA Resources
Further study details as provided by Bristol-Myers Squibb:
Primary Outcome Measures:
- Clinical Benefit Rate defined as percentage of subjects with a complete response, partial response, or stable disease for at least 6 months [ Time Frame: Every 8 weeks according to CT scan ]
Secondary Outcome Measures:
- Progression Free Survival: defined as time to disease progression [ Time Frame: Every 8 weeks ]
- Objective Response Rate: defined as percentage of subjects with 'complete response' or 'partial response' [ Time Frame: Every 8 weeks ]
- Frequency and severity of adverse events in all subjects [ Time Frame: Every 4 weeks ]
|Study Start Date:
|June 2010
|Study Completion Date:
|December 2010
|Primary Completion Date:
|December 2010 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Active Comparator: BMS-690514 + Letrozole
Drug: BMS-690514
Tablets, Oral, 200 mg, once daily, ~ 12 months depending on responseDrug: Letrozole
Tablets, Oral, 2.5 mg, once daily, ~ 12 months depending on response
|Active Comparator: Lapatinib + Letrozole
Drug: Lapatinib
Tablets, Oral, 1500 mg, once daily, ~ 12 months depending on responseDrug: Letrozole
Tablets, Oral, 2.5 mg, once daily, ~ 12 months depending on response
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Documented invasive breast cancer
- Greater than 10% tumor cells positive for estrogen receptor and/or progesterone receptor
- HER2+ and HER2- (Human Epidermal growth factor Receptor) disease
- Rapid disease progression despite treatment with tamoxifen, anastrozole or exemestane
- ECOG Performance status = 0 or 1
Exclusion Criteria:
- Prior hormonal therapy for metastatic disease
- Prior hormonal therapy with letrozole for adjuvant disease
- Symptomatic brain metastases
- Prior treatment with any tyrosine kinase inhibitor
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01068704
Please refer to this study by its ClinicalTrials.gov identifier: NCT01068704
|United States, Texas
|Texas Oncology-Abilene
|Abilene, Texas, United States, 79606
|Texas Oncology-Beaumont
|Beaumont, Texas, United States, 77702
|Us Oncology Central Pharmacy
|Fort Worth, Texas, United States, 76177
|United States, Washington
|Yakima Valley Memorial Hospital/North Star Lodge
|Yakima, Washington, United States, 98902
|Local Institution
|Rosario, Santa Fe, Argentina, S2000DSK
|Local Institution
|La Rioja, Argentina, 5300
|Local Institution
|Colima, Mexico, 28030
|Local Institution
|Lima, Peru, 34
Sponsors and Collaborators
Bristol-Myers Squibb
|Study Director:
|Bristol-Myers Squibb
|Bristol-Myers Squibb
More Information
Additional Information:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on June 23, 2017
Additional Information:
For FDA Safety Alerts and Recalls refer to the following link: http://www.fda.gov/MEDWATCH/safety.htm
|Responsible Party:
|Bristol-Myers Squibb
|ClinicalTrials.gov Identifier:
|NCT01068704 History of Changes
|Other Study ID Numbers:
2009-016622-13 ( EudraCT Number )
|Study First Received:
|February 12, 2010
|Last Updated:
|September 23, 2015
Additional relevant MeSH terms:
Breast Neoplasms
Neoplasms by Site
Breast Diseases
Skin Diseases
Antineoplastic Agents
Protein Kinase Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Aromatase Inhibitors
Steroid Synthesis Inhibitors
Estrogen Antagonists
Hormone Antagonists
Hormones, Hormone Substitutes, and Hormone Antagonists
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on June 23, 2017


text:
" Brand: Orla Kiely / Gender: Women "
This rich aromatic fragrance blends notes of earthy geranium with opulent myrrh, creating a scent that is truly comforting and warming. Presented in a stylish Orla Kiely gift box. Set contains: Geranium and Myrrh Mini Candle 75g Geranium and Myrrh Mini Diffuser 30ml.


text:
Ampersands have long been the character in a typeface with which typographers can indulge themselves. Sweeping curves, flirtatious finishes and bold statements – these are the things that make ampersands an exciting character to use and, better still, to design. There are, however, two problems.
Smashing (2008). Articles>Typography>Graphic Design>Fonts
It doesn't matter how many hours of video and megabytes of graphics can be stuffed onto a silver platter, typefaces still serve an essential function that can't be duplicated by other means--transmitting complex intellectual and emotional messages in a very concise and precise way.
Will-Harris, Daniel. Typofile. Design>Typography>Fonts>Emotions
I like bit-mapped screen fonts. In fact, I prefer old-fashioned bit-mapped screen fonts to anything that ATM, TrueType, or Speedo can throw up on the screen. If we're expected to read documents on screen, we need better type than they can offer.
Will-Harris, Daniel. Typofile (1996). Design>Typography>Fonts>Online
The purpose of the Character Design Standards is to state the general rules for character shapes in Latin based languages in digital fonts. Primarily defining the guidelines designers use for character alignments, both vertical and horizontal and how these relate to other similar characters or character groups.
Microsoft (1999). Design>Typography>Fonts>Online
Comic book writers aren't the only ones who can use silly, wacky and irreverent fonts. You, too, can give your work a fresh and light-hearted look with one of these fine, fun fonts.
Strizver, Ilene. Upper and lowercase Magazine (2008). Articles>Typography>Fonts
A Comparison of Two Computer Fonts: Serif versus Ornate Sans Serif
Fonts are described in terms of their face, style, size and color. There are two main types, namely, serif and sans serif. Serif fonts have small appendages at the top and bottom of the letter. Serif fonts are the preferred fonts for large blocks of text, since the serifs are thought to help to distinguish each letter and thus, make it easier to read strings of characters. Sans serif fonts consist of only primary line strokes and are therefore simpler in shape, e.g. Arial and Futura. In standard typography these fonts are used primarily for short phrases, e.g. headings. This study compares reading performance between an ornate sans serif font (Gigi) and Times New Roman. The traditional measures of reading speed, comprehensibility, and subjective preference were employed.
Morrison, Sarah and Jan Noyes. Usability News (2003). Design>Typography>Fonts>Online
Graphic designers love the convenience of today's computer-created type designs, but too much perfection can get boring. When your eye gets tired of all those flawless, digitally-precise letters, it's time to explore distressed typefaces. They're weather-beaten, inconsistent, and utterly, irresistibly human.
Strizver, Ilene. Upper and lowercase Magazine (2007). Articles>Typography>Fonts
Don't Be Afraid of Serif Fonts
As the practice of Web design ages, some common rules and "best practices" inevitably embed themselves in the craft. Among these are the processes for using specific types of semantics when coding your site, like using divs as hooks in your X/HTML for your CSS, and making your page beautiful and functional that way. Another is to ensure readability of your site by choosing a proper number of fonts (generally, no more than three or four, and for the minimalist, one or two).
Rodriguez, David. Web Page Design for Designers (2008). Design>Web Design>Typography>Fonts
Eighty Beautiful Typefaces For Professional Design
Which typefaces are "bulletproof"? What fonts can be used effectively in almost every Corporate Design? And what are the options for unique, but still incredibly beautiful typefaces? We have answers. Over the last few days we've browsed through dozens of type foundries, read dozens of designers' articles about typography, analyzed font rankings and visited bookmarked font-related suggestions. So this post has 'em all. Well, OK, at least many of them.
Friedman, Vitaly. Smashing (2007). Articles>Typography>Fonts
Typographically, the Euro symbol had a difficult birth. Instead of defining a currency symbol, the European Commission dictated a logo. The inclusion of the character in computer fonts is being delayed. Both copywriters and designers struggle with inadequate solutions. The five-year history of the Euro mark, or: How typeface designers and corner-store owners restore the health of a character.
Siebert, Jürgen. Font Magazine (2003). Design>Typography>Fonts
Everywhere You Look: Helvetica
As a technical communicator, I am fascinated by typography. Different typefaces can create different moods, reduce or improve readability, and affect the overall persuasiveness of a communication. Helvetica, however, seems to transcend these characteristics of type.
Opsteegh, Michael. Putting Your Best Font Forward (2009). Articles>Typography>Fonts
Examining the Legibility of Two New ClearType Fonts
This article introduces six new ClearType fonts developed by Microsoft. Legibility of two of the serif fonts, Cambria and Constantia, is compared to the traditional serif font Times New Roman. Results show that the legibility, as measured by the number of correct identifications of briefly presented characters, was highest for the new font Cambria, followed by Constantia, and then Times New Roman. Old style digits, such as 0,1, and 2, used in Constantia resulted in confusion with the letters o, l, and z. Times New Roman symbols were confused with both letters and other symbols.
Chaparro, Barbara S., A. Dawn Shaikh and Alex Chaparro. Usability News (2006). Design>Typography>Fonts>Online
Helvetica is back, bigtime. On the street, it's in campaigns for companies as different as IBM and The Gap. At the online font retailers, it tops the sales charts. In the metaculture, Getty Images uses it to express control of the visual world. It's quite shocking to look at the font sales charts, and realize that the serif genre has dropped off the map. But you know this already, because whenever you try a serif font in a layout it doesn't look right — too oldfashioned. But perhaps that's the wrong term, because the sans faces ruling the roost today are anything but contemporary, mostly dating from the mid-20th century, many from a lot earlier.
Shinn, Nick. ShinnType (2003). Design>Typography>Fonts
Their logo is COPPERPLATE. We can't shop here.
PVP Online (2009). Humor>Typography>Fonts
The @Font-Face Rule And Useful Web Font Tricks
The possibility of embedding any font you like into websites via @font-face is an additional stylistic device which promises to abolish the monotony of the usual system fonts. It surely would be all too easy if there was only one Web font format out there. Instead, there's quite a variety, as you will get to know in this article.
Hermann, Ralf. Smashing (2011). Articles>Web Design>Typography>Fonts
Acrobat's intelligent font substitution is a godsend for office documents, but it can be a nightmare in situations where font fidelity is important. If you're a graphic designer, then you need to know how to work with fonts in PDFs.
Perets, Shlomo. Creative Pro (2004). Design>Typography>Fonts>Adobe Acrobat
One of the original ideas behind the Web is that readers should have control over how things look, since only they know what color combinations, point sizes, and so on they find easiest to read on their particular combination of hardware and software. That said, there's a difference between designing for the World Wide Web, where your documents can be read by anyone, and designing for an intranet, an internal network that's accessible only to people within your organization. On an intranet, you can (theoretically) know exactly what hardware and software your readers are using, so you can control the look to a much greater extent.
Ivey, Keith C. Editorial Eye, The (1997). Design>Typography>Fonts>Web Design
Sometimes a simple idea can make a big difference in your work. One recent improvement to major design applications is the addition of glyph palettes. This handy feature will help you find and use the exact character you're looking for – even if your font has thousands to choose from!
Strizver, Ilene. Upper and lowercase Magazine (2007). Articles>Typography>Fonts>Software
Help, I'm Lost in a Sea of Typefaces! (Part 1)
Decisions, decisions, decisions! One of the most challenging aspects of any design project is choosing the typefaces. There are now more than forty thousand fonts on the market and that number is growing daily, which makes the search for the "perfect" typeface only slightly more daunting than looking for that proverbial needle in a haystack. With a little planning, however, you'll find that selecting appropriate typefaces is far more manageable than it appears.
Strizver, Ilene. Upper and lowercase Magazine (2002). Design>Typography>Fonts
The history of Helvetica includes a number of twists and turns. There are, in fact, two versions of Helvetica. The first one is the original design, which was created by Max Miedinger and released by Linotype in 1957. And secondly, in 1983, D. Stempel AG, Linotype's daughter company, released the Neue Helvetica® design, which was a re-working of the 1957 original.
Strizver, Ilene. Upper and lowercase Magazine (2008). Design>Typography>Fonts
HTML E-Mail: Text Font Readability Study
The computer screen is a much different medium than the printed page. The resolution is much less, about 72 dots per inch (dpi) for the computer screen vs. 180 dpi or 300 dpi or even higher for printed matter. My readers clearly prefer sans serif fonts to serif fonts for body text. Therefore, in my HTML e-mail newsletters -- and on my websites -- I am moving toward 12 pt. Arial for body text, and Verdana for 10 pt. and 9 p. fonts.
Wilson, Ralph F. Web Marketing Today (2001). Articles>Web Design>Typography>Fonts
There is no denying that the most important thing about eLearning is solid content. But could you be inadvertently making your content harder to read and understand by using the wrong fonts? Is good font selection really important? Read on to discover the many surprising ways fonts can affect your content.
George, A.J. I Came, I Saw, I Learned (2010). Articles>Typography>Fonts>Education
Increase Your Font Stacks With Font Matrix
I have put together a matrix of (western) fonts showing which are installed with Mac and Windows operating systems, which are installed with various versions of Microsoft Office, and which are installed with Adobe Creative Suite. The idea of the matrix is that use can use it to help construct your font stack.
Rutter, Richard. Twenty-Four Ways to Impress Your Friends (2007). Articles>Web Design>Typography>Fonts
Live Font Interpolation on the Web
We all want to design great typographic experiences—while serving users on a huge array of devices. But today's type is inflexible and doesn't scale. We can solve this problem by making webfonts more systemized and context-aware, and live web font interpolation—the modification of a font's design in the browser—can help us get there. Andrew Johnson points the way.
Johnson, Andrew. List Apart, A (2015). Articles>Web Design>Typography>Fonts
Mark van Bronkhorst's recent type family MVB Verdigris is easier on the eyes than many of the existing typefaces that are used for text at small sizes.
Berry, John D. Creative Pro (2004). Design>Typography>Fonts>Online


text:
Bathing your toddler
Most toddlers love bath time each day because once the washing has been done, they can have wonderful time playing with the water. Stock up on plastic cups and bottles, funnels, along with boats and squirters, and your great challenge at bath time with be convincing your toddler to get out of the bath!
Having a bath at the end of a day of play and exploration, is the best way to encourage your busy toddler to unwind, relax and prepare for bedtime.
Some toddlers become afraid of the bath. If this happens, take your toddler's fears seriously, as they are very real to her. To help overcome a fear of the bath you can try:
- taking a bath with your toddler
- letting her sit in the bath without water in it
- getting her to leave the bathroom before you take the plug out, as some toddlers are afraid of getting sucked down the plug hole
- having a shower with her
- letting her sit in the baby bath in the big tub (if she still fits)
This article was written by Ella Walsh for Kidspot. Sources include Raising Children Network
Related Topics
- 1. How much sleep does my toddler need?
- 2. Going to bed problems
- 3. Reading with toddlers
- 4. Learning songs
- 5. Cooking with a toddler
- 6. Best books for toddlers
- 7. Play stages for toddlers
- 8. Feeding toddlers
- 9. Encouraging your toddler to eat
- 10. Toddlers and fussy eating
- 11. Toilet training basics
- 12. Discipline tips for 1 - 3 year olds
- 13. Toddler fears
- 14. Why does my toddler lie?
- 15. Best toddler tips
- 16. 10 tips to deal with tantrums


text:
If you want to read Yiddish on the Internet, you need to have Hebrew fonts installed on your computer and use a browser that supports Hebrew encodings.
Attention Machintosh users: The Macintosh version of the Microsoft Internet Explorer doesn't seem to support Hebrew letters at all. The recommended browser for Mac is Mozilla/Firefox on OS X v.10.2 or higher.
|Back to Homepage| Subscribe| Contact Webmaster


text: "Daniel P. Berrange" <berrange redhat com> wrote: ... > No, they are all correct AFAIK. The *existing* code was buggy using > the wrong macros in many places. ... > You need to compare with the function context shown in the patch, rather > than assume the original code was correct :-) Yeah, "assuming" can cause trouble ;-) It would help others down the road if there were a note in the ChangeLog that this change set also fixes several bugs. Some might even prefer to put the minimal bug-fix-only change into its own change set. From an N-year maintenance perspective, that's preferable: less risk of it interfering with other changes. Otherwise, the fixes are buried under all the similar-looking-but-syntax-only changes. If you don't mind splitting this patch, I'll be happy to supply the equivalent pair of replacement change sets.


text:
Will this work alright?
2 Attachment(s)
Wanting to check my work before I begin. Thx.
Looks like the old trap is going directly into a main drainline. This would also serve as a vent for that short of run. Going as far as your drawing indicates (looks to be at least 5') would require a seperate vent line. This vent would go back to and connect to the main vent. Maybe I am misreading your drawing.
No it is not too far really. It is maybe 3' where I will be putting the new drain/trap that's all.
So would that be fine if it was within about 3'. The T section would be even closer than that. The drain/trap would be about 36" from original. Not very far at all. Also: When I cut into the 2" drain to put my T in, will the pipe give me enough lateral play to slip the T in?
1 Attachment(s)
If you have the room in the bay in the floor, this is what I would do.Good luck.
So your saying to cut into the 2" drain and run my P trap into it then raise the other cut half coming from the wall of the 2" that extends back to the vent up and Wye into the 2" after the P trap?
So I would just use a reducer to go from my 1 1/2" P trap and go straight into the exhisting 2" drainline. Now for the vent. After I cut the drain line would I use the back half of the 2" drain line or just go from the vent going up the wall and get rid of the old T for the old trap and run new 1 1/2" pipe for the vent? Then would I use a Wye and tie into the drainline? Approximately where would I Wye into the drainline after the trap? I really appreciate the help. Your pic helps alot. Picture is worth a thousand words. All of this would then be the "professional" way to go?
Look right now fellas?
1 Attachment(s)
http://www.diychatroom.com/attachmen...1&d=1226104778I hope you can understand this. lay-out the new fixture drains location at the waste & overflow outlet, that is where the trap inlet goes. the whye goes before the trap when looking at the sketch your left, the vent runs from the branch of the y & street 45 towards the vent on your right. You may have to offset the horizontal vent at the partition to align with the existing vertical vent.
The y is going to be 1-1/2" you can reduce the existing 2" before the y with a 2" by 1-1/2" reducing coupling. this will give you a little more room to work with.
THANK YOU so much. I think I can handle that. Don't see what was so hard about it. Just couldn't get the right details. Any specific distance to put the Y before the trap? I can basically cut out the old T where the old trap went into the vent and just run the vent to the Y then. That old plumbing by that wall is actually in the way of the whrilpool sitting closer to the wall anyways.
And just to double check there is no problem going from the ABS to pvc,sch40 as long as I use the "transition cement"
I can just cut this out and makehttp://i12.photobucket.com/albums/a2...gfortub005.jpg it tighter to the wall or come up from underneath inside the wall correct?
Mass does not allow the transition from ABS to PVC using the cement , we either use a male to female adapter or a no-hub coupling. If I were you I woud use the ABS rather than the PVC. Less expansion in ABS plus it seems the right thing to do keep it uniform.
The Y should not be closer to the trap than two pipe diameters nor more than 5 feet away. Varies in different states
Once again thank you. You have helped tremendously. I was beginning to think I was gonna have to call a plumber but after you took time to show me I don't see why I can't handle it myself do you? I live in Ohio and i'm not sure about code for ABS to PVC. I already got the cement. I actually didn't see any ABS, I thought it was rare nowadays. You wouldn't have an example photo or a link to show what kind of connection your referring to?
Also if I wanted to provide more room for the plumbing under the floor could I run from the wye 1 1/4" pipe to the 1 1/2" vent for sake of space? Or would that be cobbling?
ONCE AGAIN I thank you greatly appreciate your time and knowledge.
http://www.fernco.com/NH.asp no-hub coupling photo 4 band best
1-1/4 is allowed in ma but parts difficult to get same with ABS. ABS or PVC Male adapter & female adapters self expanitory or look them up on the web.
Thx again plumcass for the diagram. Been sick all weekend so haven't got much done. I got the tub drain/overflow on and 2 of the island walls done so now I know where the whirlpool will sit. I have to cut a decent section of the subfloor out to do the new plumbing work. I might go ahead with the Fernco no hub connectors. I see HD and Lowe's has them. The way it will be vented routed as to your diagram and everything would be to code if it was inspected? Not going to be, but I don't like to half ass. I like to do things right. I take pride in my work even if I am just a DIY'er.
Got to run the dedicated circuit still but that will be simple. Lots of work left to do but I got plenty of time. I will keep you posted. Thx again.
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text:
Well, how do you fare compared to the Zeitgeist?
Chat up your fellow wooters and let us know how lame this poll was or what obvious choices we missed.
For example: Was this poll a) STUPID, b) DUMB, c) POINTLESS or d) ALL OF THE ABOVE?
Belgian ales.
When I was in a beer mood, it was more a brand than style choice. I liked trying different Dogfish Head Brewery experiments/regulars.
Whiskey until you can't taste the beer, then whatever. Usually more whiskey though, honestly.
I don't always drink beer, but when I do, it's either Sorachi Ace (Saison) or Monster Ale (Barleywine).
thestone wrote:Belgian ales.
Yes, Belgian beer is the best!
What's wrong with the Pilsner?
My favorite is Posthumous Pale Ale or maybe Dewback Dry.
Do I see a side sale in the making?
Nut Brown Ale
pils/pale ale really. . . but i went IPA since it's the closest
The kind that involves hard liquor and not beer.
I said IPA but I love a good Chocolate Bock.
Please, please, please let this mean we have a new .woot coming!
FrostByte wrote:Please, please, please let this mean we have a new .woot coming!
I prefer the beer of a root variety. IBC Rootbeer or Barq's Rootbeer.
I prefer pale ale over India pale ale, and I like a good amber, too.
I'm beer stupid, I can never remember the difference except the colors go with the names and dark isn't always bitter. I like not bitter, but I'm willing to try new ones all the time. Kinda the same with wine. Can't remember what I like, so always trying something new.
Oktoberfest Marzen, preferably mine.
cole103 wrote:Oktoberfest Marzen, preferably mine.
Oh, yes. Paulaner & Spaten make a great Oktoberfest Marzen. I LOVE those German beers, and have not been able to make one as good as that at home.
My tastes for beer kind of change with the seasons.
In summer, I like lighter German lagers, IPA's, Pale Ales, amber ales, etc...
In the winter, the Stouts, Porters, cask-conditioned stouts, more IPA's, I love the Russian Imperial Stouts (North Coast makes a great one...).
Our sports bar had Obsidian Stout on nitrogen tap. Oh, yeah...
Of course, a quality 12+ year old single malt scotch, with one rock, is good too...
All styles, but right now, probably sours.
A&W Root Beer.
Never got the taste of Beer, Coffee, Dark Chocolate.
(Gasps of Horror)
I basically love all types of beer but I'd say my favorite style is gueuze.
Mmm... beer.
(That's pretty much went through my head when I was reading through the choices and picturing which one I would like to be drinking right now.)
Pilsner, Belgian, chek, german
There's a couple of Porter's that I can drink any day, but I usually go more IPAs when it's summer, something light on the golf course, and something heavier on the mountain after snowboarding.
I love a good Nut Brown, it's just hard to make a good one!
My favorite kind of beer is ROOT.
~I'm a Mormon.~
Interesting that this popped up in a feed today...
Hefeweizen overall probably, my favorite brewery is Boulevard in Kansas City, MO and they make a fabulous wheat beer. I also love a good stout, so that's a close second. Favorite seasonal beer is pumpkin ale by far.
I'm off work early today and am drinking Weihenstephaner Original, one of the best lagers in the world. ;)
FrostByte wrote:Interesting that this popped up in a feed today...
Love this! Plus the descriptions of my favorites: amber, stout, and pumpkin. Although some of my all-time favorites are Oktoberfests and a good porter every now and then...
Right now I really like Sours, particularly Femme Fatale from Boneyard Brewery in Bend, OR.
fubar1982 wrote:+1
to quote Lister, from Red Dwarf,
Being underage, I have only had a sip of a bad IPA, which happened to be a bad bottle. However, while this may not count I have brewed several batches of ginger beer. I would recommend it highly to anyone who doesn't like "real" beer. My personal favorite store bought brand is Reed's Jamaican style ginger beer
I'm in middle school. Therefor, I don't think I can say. Ask this poll again when I'm 21 and I'm sure I will know.
Whatever someone else is buying.
My favorite kind of beer is ROOT.
View All →


text:
Historically, it is the responsibility of the United States Congress to focus on the national interests of their country, not that of the nation of Israel. After three decades of conflict with the nation of Iran, a group of five leading countries banded together to hammer out an agreement to cap Iran's work on nuclear weapon development. It does place limits on this work, but to Senator Schumer and fellow Republicans and Democrats compelling Iran to halt work on nuclear weapons is selling out Israel. Prime Minister Benjamin Netanyahu terms the agreement an "historic mistake." Israel President Shimon Peres disagrees, "the success or failure of the deal will be judged by results,not words." Perhaps, Senator Schumer believes President Peres wants to sell out Israel?
Bibi Netanyahu has refused to work with Palestinians in order to reach an agreement. He has sabotaged the rights of Palestinians, he has insulted Palestinians, he has hampered a Palestinian government which seeks peace with Israel. THAT, is an "historic mistake!"


text:
In the Catedra UNESCO of Sustainable Development, we are teaching Online Courses of building simulation models in Ecology and Environment. You can find more info in: http://www.catunesco.upc.es/cursos/angles.htm
Students need to work in this course 20-40 hours, depending on what they know previously in this field, and depending of how deep they want to understand the contents of the course. This means 3-6 weeks usually. This is a self-paced course: you decide how fast you like to work on it. When you will finish this course you are going to be able of create models with the dynamic simulation software Vensim, which is like Stella, Powersim, ithink, Dynamo and similar ones.
This is a course addressed to people with few hours to study, and the contents has been elaborated trying to avoid unnecessary materials, and really I am very happy seen how fast the students achieve the skills to build interesting models.


text:
Jadee Shaw Makeup Artist
Jadee - Formerly NikoleModel Female South Hill, Washington, US
My MM URL: http://www.modelmayhem.com/jadeeshaw
Mayhem # 40473
About Me
Please visit my MUA profile as that is where most of my work and passion is being currently directed! I keep my modeling cameos to a very select few now-a-days...
Let's see... where to start. Well, I started modeling at age 12, but wasn't really able to apply myself until the age of 18. Since then, I have had the privilege of shooting with some of the NW's best photographers and help new ones grow. I'm a very fun person that likes to get to know people. There's always so much to learn!
FYI's: I have 3 tattoos--a triquetra knot in between my shoulder blades, a quarter sized piesces symbol lower left abdomen, and a brush stroked Ohm symbol with cherry blossoms on top of my right foot. I have my lip pierced but this can come out for shoots if requested.
Have you worked with Jadee - Formerly Nikole? Add Credits for Jadee - Formerly Nikole! >>
Credit Notes
To name a few (I know I missed a ton! Sorry!):
Lund Photography
Paris Photography/Don Conrad
Fred Dimaano
Ted Leung
Orion Ahrensfeld
Roy Harper
Peter Mui
Brady Photography
Barry Druxman
Tammy Murray Photographics
Tracy Zabriskie
Keen Photography
David Stratton
R. Olson Photography
Matt the Photographer
Jadee Shaw Makeup Artist
falco Photographer
pMui photography Photographer
Paris Photography Photographer
Alex_Lim Photographer
Lund Photography Photographer
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