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What Are Enzyme Markers?
Enzymes are highly specialized complex proteins that aid chemical changes in every part of the body. For example, they help break down food so your body can use it effectively, and they help your blood clot. They're present in every organ and cell in your body. Your body needs enzymes to function properly.
Enzyme markers are blood tests that analyze specific enzyme activity in the body. Some inherited diseases or conditions can cause these enzymes to stop working or be less efficient.
Monitoring the rise or fall of enzyme levels can aid in the diagnosis of a variety of conditions. Your doctor can order a blood test for enzyme markers or a routine blood test to help them discover abnormalities. In some cases, you may need to take the test multiple times over the course of several days to measure changes over time.
What Are the Common Types of Enzyme Markers?
CPK Isoenzymes
The CPK isoenzyme test measures the creatine phosphokinase (CPK) in the blood. CPK enzymes are in the heart, brain, and skeletal muscles.
CPK-1 resides mostly in the brain and lungs. Increased levels of CPK-1 can be due to:
- brain cancer
- brain injury, stroke, or bleeding in the brain
- pulmonary infarction, which is the death of lung tissue
- seizure
- electroconvulsive therapy
CPK-2 levels rise following a heart attack. Increased levels of CPK-2 may also be due to:
- open heart surgery
- inflammation of the heart muscle
- heart injury
- defibrillation
- electrical injuries
High CPK-3 levels can be a sign of muscle stress, a crush injury, or injury due to:
- muscle damage, dystrophy, or inflammation
- intramuscular injections
- electromyography, which is a muscle and nerve function test
- recent surgery
- seizures
- strenuous exercise
Heart Enzymes
Some heart enzymes slowly enter your blood if you've had a heart attack and your heart is damaged as a result. A general test for emergency room patients with heart attack symptoms is a test for the presence of heart enzymes in the blood.
Liver Enzymes
Elevated liver enzymes may be due to inflammation or damaged liver cells. Usually, elevated liver enzymes aren't the result of a serious or chronic liver disease. They can be due to:
- prescription medications, such as statins
- over-the-counter (OTC) medications, such as acetaminophen
- alcohol consumption
- heart failure or heart attack
- liver disease, such as hepatitis, fatty liver disease, cancer, and cirrhosis
- obesity
- celiac disease, which is a digestive condition
- viruses, such as cytomegalovirus infection, mononucleosis, and Epstein-Barr virus
- inflammatory diseases, such as dermatomyositis, pancreatitis, and gallbladder inflammation
- muscular diseases, such as muscular dystrophy or polymyositis
- hemochromatosis, which is a disorder in which there's too much iron in the blood
- an underactive thyroid
- Wilson's disease, which is a disorder in which there's too much copper stored in the body
How Are Enzyme Marker Tests Performed?
The test is a routine blood test, and it takes place in a laboratory. No fasting or special preparation is necessary. However, tell your doctor about all prescription and OTC medications and supplements you take.
A blood test involves the following steps:
- A healthcare provider will use an antiseptic to clean a small area of your arm, usually the inside of your elbow or the back of your hand.
- They'll then wrap an elastic band around your upper arm to create pressure and make it easier to access a vein.
- They'll insert a needle into your vein and blood will flow into a small vial. You'll likely feel the stick of the needle or a stinging sensation.
- After filling the vial, the healthcare provider will remove the elastic band and the needle.
- They'll place a bandage over the puncture site and send the sample to a lab for analysis.
The procedure should take only a few minutes.
What Are the Risks Associated with Enzyme Marker Tests?
Your arm may be sore at the puncture site and you might have some mild bruising or brief throbbing.
Most people have no serious or lasting side effects from a blood test. Rare complications include:
- bleeding
- lightheadedness
- fainting
- infection, which is a small risk whenever the skin is broken
Contact your doctor immediately if you have any of these symptoms.
What Do the Test Results Mean?
Abnormal test results can indicate a variety of problems from disease to a simple muscle strain because enzymes are present in every cell of your body. Your doctor will be able to determine a proper course of treatment based on your exact enzyme marker levels and the symptoms you're having.


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Shindand security transitions to Afghan forces
Shindand security transitions to Afghan forces
HERAT CITY (PAN): As part of the third phase of transition, the security responsibility for the Shindand district of western Herat province was handed to Afghan forces, officials said on Thursday.
A ceremony marking the security switch was held on Wednesday afternoon, with Afghan National Army (ANA) officers, civilian officials and NATO representatives in attendance.
Provincial police chief, Brig. Gen. Rahmatullah Safi, told Pajhwok Afghan News Afghan security forces had the capability to maintain peace in district.
Security responsibility for 12 districts of the province has already transitioned to Afghan forces. Chasht-i-Sharif and Oba districts would change hands in near future, Gen. Safi added.
Related Article
Download "Pajhwok" mobile App, on your smartphone to read and access latest news, features, interviews, videos and photos about Afghanistan.

subset: commoncrawl


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Vinyl fence gate rubs
238 Attachment(s)
About a month ago I had a new vinyl fence installed by a contractor. I am happy with the fence, but recently the gate door has seems to stick a little when I try to close it. The vinyl part of the door hits the latch bolt on the fence part and seems to need an extra good tug to close fully. I'm affraid someone is going to leave it open partly and the dog will get out.
The post doesn't look too off level, and if I push the fence to the left some, its enough to fully clear the bolt. Is there an easy way to fix this? The posts are 3 ft in the ground, but only concreted about a foot deep. We have had a lot of rain lately, so It may be possible the ground softened up some and the weight of the gate pulled the post to the right some. There is only one section left of the gate (we butted up to our neighbors post)
If I called the contractor back, would that be "nit-picky" ? Can I fix it myself?
Post a picture.
I would have set the gate post with 2 bags of concrete in a tapered shaped hole.
Sort of level tells us nothing, you need to use a real at least 2' level to check it.
May be as simple as changing latches, some are self adjusting.
238 Attachment(s)
Here are the pics:
The level pics at the bottom are in the order as the picture with the numbers for your reference - I took the leveling from the inside of the fence though (if that matters any).
238 Attachment(s)
more Pictures:
238 Attachment(s)
I thought about trying to push in the fence some and secure it with a screw inside the post tube.
Any other thoughts? Should this be something the contractor should make good on? The wife is after me to have this fixed.
199 Attachment(s)
That's unacceptable, call the contractor back and make him fix it.
Those vinyl gates almost always start to sag shortly after installing so I alway install an adjustable turn buckle as I'm installing the gate. There's only thin walled vinyl to attach it to so I use Stainless steel round head machine screws long enought to go all the way through and cap nuts with washers under them.
Also that style latch counts on nothing having moved. I use one that looks just like yours but the metal rod part is not fixed on the ones I use.
It can move up and down slightly. There sold right next to the one you have in the hardware dept at Lowes or HD.
I know for a fact wet 4 X 4's are going to bend and twist so I try to set my gate post further apart to allow for that.
I'm a contractor myself, and I think your contractor should be held responsible. We actually have a lifetime guarantee on material AND labor for vinyl fence, but I know that's unusual. Still, ANY contractor should be guarantee the work for one month! And if it's that bad after a month, how is the fence going to be after a year?
We generally set our posts in at least two feet of concrete and use metal inserts for added support on the gate posts.
238 Attachment(s)
Well it hasn't gotten any worse but it's not better either. I tried calling the contractor 4 times - twice on his office line and twice on his cell phone (left voicemails each time) and haven't heard a single response back. The guy apparently doesn't even have the decency to call me back :furious:
I'm thinking of putting in a claim with superpages since I got his information from there. They offer some type of guarantee on the contractors they list.
My brother in law gave me an idea but I'm not sure if it will work. He suggested staking the corner post back so it pulls the gate left then filling the tube with cement and hope it drys to the new contour. Sounds good on paper, not sure in practice...Any thoughts? All the tubes shown are empty inside.
I also thought of installing a metal handle on each side of the gate so you can close it harder. No haven't done anything yet because I keep hoping he will call me back...
Oh and did I mention since this week the springs don't work on the hinges so it doesn't automatically close anymore either....
Are the hinges adjustable?
Hard to tell from your pics; they are too far away to get any details.
I had a similar issue last year but try the easy stuff first.
238 Attachment(s)
Not that I can tell - they are bolted to the post. The hinge fits right onto the corner and appears to be fixed.
There are quite a few problems with this hack. Should have 3 hinges on a 6 ft' gate, should be hinged on the high side of a hill not the low reasons are frost heaves, the fence sections seem to follow grade and the gate does not, looks tacky, should have noticed the down spout and water run off next to gate, makes you wonder if the cement cured properly, gate posts should be cemented totally not just a foot, I could go on but you deserve all your money back from this thief.
238 Attachment(s)
Yeah it looks like I got screwed. He still hasn't returned any of my phone calls. I would have thought someone on super pages would be ok (at least that's how they advertise).
When he was finishing up the work one of the hinges broke when he was trying to adjust the tension. I'm glad he was at the end because he immediately got into a rage fit, yelling the F word in front of all my neighbors, threw his ladder on my lawn, threw a screw driver into the street barely missing my neighbors cars, then slammed his wooden toolbox off his truck onto my sidewalk busting it into a million pieces with parts everywhere.
I was highly embarrassed and refused to pay him the remaining deposit half until the hinge worked. He left and his son came the next day to fix the hinge and apologize for the actions of his father, the guy didn't even have the decency to apologize himself.
The gate worked when the son was finished and it wasn't until a little later it started to hit, I guess like you said it sagged some.
I'm not sure really where to go from here. I'm honestly scared to call him back but the wife is after me to have him fix it...but he won't return my calls...
Might check out these hinges:
Local fence place used them on my PVC and they are excellent and allow for adjustment. A bit pricey but if they work...
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|by jpflys
|Date Added: Sunday 08 January, 2012
I ordered this thinking that it would fit my casserole and it was too small. I didn't see any measurements listed and thought that they must be right and I was wrong.....but nope...I should have ordered the 2 1/2 size to fit my 1 1/2. Duh....and now I have to deal with the exchange.
|Items 1 - 1 of 1 reviews


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I am only on day three of Invisalign, but so far everything is going fine. I was pretty miserable for the first two days from the pressure and tightness of the trays, but I was told that's when the teeth move the most. I took Ibuprofen which took some of the edge off. When I woke up today most of the discomfort was gone. Now I'm just trying to get used to the mouth full of plastic. I have friends who have done the whole treatment and say their experiences were similiar, but it was well worth it. So far, I think I can handle it.
I am only on day three of Invisalign, but so far...
Was this review helpful? {{ voteCountOthers + ' other' + (voteCountOthers == 1 ? '' : 's') }} found this helpful


text:
Mobile Notary Service + Less than 5 Travel Miles
Notarial Services are $10.00 per Notary Stamp (Do not allowed anyone to charge you more than the amount specified above. The State of Florida only allows a maximun of $10.00 per Notary). Our milleage is always measure from our central office. This means it doesn't matter where we are at the moment you call us, we will only charge milleage as if we were coming from our central office, wich address is:
4281 Reflections Blvd South. Sunrise, Florida 33351. Call us:
Open the Door & Sign Your Testimonial


text:
Learn about l'amour à la française during this discussion series covering Gallic sensuality. Cultural historians and writers weigh in at "Did the French Invent Love?" (Nov 20 at 7pm), sex therapist Esther Perel talks about common sexual fantasies at "Inside the Erotic Mind" (Dec 2 at 7pm) and biological anthropologist Helen Fisher explains the science of love and lust at "Behind the Boudoir: The Secrets of Sex Appeal" (Dec 9 at 7pm).
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|French Institute Alliance Française
22 E 60th St
New York
|Cross street:
|between Madison and Park Aves
|Subway: N, Q, R to Fifth Ave–59th St; 4, 5, 6 to 59th St
|$20–$25, three-talk package $50–$65
To improve this listing email: email@example.com


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Archive Home
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Study Says High School Students Falling Behind In Financial Literacy
Tuesday, 06/21/11
Steve Zind
A survey of Vermont high schools finds that while some form of financial literacy is taught in many of them, the courses are elective and they vary in what's being taught. Earlier: Spaulding Launches Financial Literacy Program
 MP3 Available
Vermont Edition
Program Seeks To Raise Financial Literacy
Monday, 06/20/11
Steve Zind
Personal finance has become more complex, making it even more critical for people to understand how to manage their money. An ambitious program at Champlain College aims to improve what Vermonters understand about saving and investing, credit and debt.
 MP3 Available
VPR News
Spaulding Launches Financial Literacy Program
Friday, 06/04/10
Lynne McCrea
Vermont's state treasurer was in Burlington Thursday to kick off a statewide "financial literacy" program for kids.
VPR News
A Look At Financial Literacy
Tuesday, 04/13/10
Jane Lindholm
Annamaria Lusardi, Director of the Financial Literacy Center speaks with VPR's Jane Lindholm about the importance of knowing basic skills to manage money and understand the financial system.
 MP3 Available
Vermont Edition
Financial Literacy
Tuesday, 04/13/10
Jane Lindholm
A down economy and confusing, complex choices are testing our ability to make wise financial decisions. We'll talk about how to improve our financial literacy. Plus, part two of our interview with author John Irving and a behind-the-scenes look at the interview.
 MP3 Available
VPR News
Weekend Conference Offers Youth "Financial Fitness"
Wednesday, 11/11/09
Ross Sneyd
A group of volunteers hopes to help Vermont youth get in shape in this time of economic recession.
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The days are gone when the term "manic depression," which pretty much referred to people who experienced both mania and severe depression, was all there was to describe the illness now called bipolar disorder. Today, the characteristics of each form of bipolar disorder allow for more precise definitions and diagnoses, for the different forms are indeed different, both in the severity of some symptoms and in the way the illnesses affect people over time.

There are three major bipolar disorders along with some more specialized diagnoses. We'll begin with a look at each of them, and then go into more detail about the types of episodes.

The Forms of Bipolar Disorder

1. Bipolar I Disorder: Also known as Bipolar 1, the single defining characteristic of this illness is that the patient has had, or is having, a manic episode. In most cases, the patient also has major depressive episodes, mixed episodes and/or hypomanic episodes. For in-depth information, see:

What Is Bipolar I Disorder? How Is It Diagnosed?

2. Bipolar II Disorder (also known as Bipolar 2): Patients with this illness have both hypomanic and major depressive episodes. In Bipolar II Disorder, the tendency is to have more and longer depressive than hypomanic episodes, and over the patient's lifetime, to have more days ill than people with Bipolar I. For comprehensive information:

What Is Bipolar 2 Disorder?

Diagnosing Bipolar II Disorder

And for a close look at the differences between Bipolar 1 and 2:

Bipolar I and Bipolar II - What's the Difference?

3. Cyclothymia is less well-known than either of the other forms, but it is still an illness that can have a profound and serious effect on those who have it. Patients with cyclothymia experience the same hypomanic episodes as people with Bipolar 2, but the depression they experience is not severe enough to constitute major depressive episodes. For detailed information, read:

What Is Cyclothymia?

Diagnosing Cyclothymia

There is also Bipolar Disorder Not Otherwise Specified (NOS). For information on this diagnosis, see:

Diagnosing Bipolar Disorder NOS

The Moods of Bipolar Disorder

The three defining moods of the bipolar disorders are mania, hypomania, and depression. Periods of these moods are called manic episodes, hypomanic episodes, and, for Bipolar I and II, major depressive episodes. Mixed episodes are possible as well, where the patient experiences periods of both mania or hypomania and depression.

1. Mania is an extremely serious condition. In addition to a mood that is over the top or extremely irritable, someone having a manic episode may experience psychosis, need to be hospitalized, and/or have his or her life seriously disrupted by the symptoms. For a close look at mania, see:

What Is Bipolar Mania? How Is It Diagnosed?

Symptoms of Mania and Hypomania

2. Hypomania, while not as severe as mania, is nevertheless a mood that can cause serious problems. For example, during a hypomanic episode, many of the same dangerous behaviors present in manic episodes, such as spending money recklessly or indulging in risky sexual behavior, may occur, having heavy consequences. In addition to the article "Symptoms of Mania and Hypomania" above, here is comprehensive information about hypomania:

What Is Hypomania? How Is It Diagnosed?

3. Major Depression in bipolar disorder is no different from the depressive episodes of Major Depressive Disorder. Here are in-depth articles on depression, including a quiz that can help you identify your condition:

What Is a Major Depressive Episode?

Warning Signs of Depression

Quiz: Could I Be Depressed?

4. Mixed Episodes can be primarily manic or hypomanic, or primarily depressed, but in each case symptoms of the opposite mood are present. The current official description of mixed episodes in the DSM IV will likely be revised in the upcoming DSM V. These two articles give information about the present diagnostic criteria:

What Is a Mixed Episode?

Diagnosing a Mixed Episode


text:
January Boxer of the Month
January Boxer of the Month
(Bio Coming soon!)
Here is Ren's Bio:
Name: Serenity May
Age: 3 years, 8 months
Nicknames: Ren, Renners, Wigglebutt, Bebé, Pretty Girl
Favorite Toy: Pink Dino Cuz, Rory the big, purple dragon & Mr. Squiggles (R.I.P.)
Favorite Treat: Peanut Butter & Coconut Oil
Favorite Activity: Playing outside or boxing with her Daddy in the house
Favorite Pasttime: Snuggling next to Mama on the couch or stealing affection from her skin babies
How did you select your boxer: We were very lucky to end up with Serenity! I came across her posted for sale through an ad online. Instantly we fell in love with her sweet face and I contacted the breeder. She was 9 weeks old when we brought her home to live with us.
As it turned out we were her 2nd owners ~ the first woman who bought her from the breeder paid for her with a fake check so the breeder got the police involved. Once the woman was found, the breeder was able to get her puppy back. She was only gone for about a week, but we were told by the breeder that when she got her back you could tell she had been malnourished because you could see her ribs and she was even possibly abused during that time...
I believe in my heart that Serenity was meant to be a part of our family. :hrtbeat: To this day Im still not quite sure who rescued who!
Lovely lady!!!! Congrats, Serenity!
Congrats, Ren! You're so beautiful!
What a picture,grats Ren!
May you have a beautifull year without any hives or bug bites :lol:
Congrats Ren! I just so love Ren...her face is one of the cutest I have ever seen :)
That's a great picture!
Congrats Ren! :D :D :D
Well, you can't argue with that face. Congrats.
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Dim the lights and break out the…eggs? These 10 foods will kick your sex drive into high gear.
15 signs that it's more than just the blues
From your diet to your medication to your mindset, here are 13 culprits of low libido.
Here are 16 facts you need to know to protect yourself from contracting or spreading a sexually transmitted disease.
Banish belly rolls for good with these easy moves to sculpt strong, sexy abs
Avoid these 8 hard-on-your heart foods.


text:
BMW 4-Series Forums (http://www.4-seriesforums.com/forum.php)
- Introductions (http://www.4-seriesforums.com/5-introductions/)
- - 428 XDrive, M Sport! from NYC (http://www.4-seriesforums.com/5-introductions/337-428-xdrive-m-sport-nyc.html)
428 XDrive, M Sport! from NYC
Just ordered my 428! AWD, MSPort... w/ Tech Pkg, Cold Weather, Driver Assist, Dynamic Handling in Alpine White and Red Leather...
Got my prod# and I should see it in mid Oct!
Welcome to the 4-series forums! White over red is a smashing combo on the 4.
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Indians sign RHP Matt Capps
Associated Press | Last updated January 31, 2013
The Indians have signed free agent pitcher Matt Capps to a minor-league contract. Capps' deal includes a non-roster invitation to spring training camp. The 29-year-old has 138 career saves in 444 appearances for Pittsburgh, Washington and Minnesota. He opened last season closing for the Twins and had 14 saves in his first 15 chances. But Capps was slowed by shoulder inflammation and pitched just four innings after June 15. The Twins declined their $6 million contract option on Capps for 2013, instead paying him a $250,000 buyout. Capps was the winning pitcher for the National League in the 2010 All-Star game. That season, he had a career-high 42 saves and a 2.47 ERA in 74 games for the Nationals and Twins. He has recorded at least 14 saves each of the past six seasons.
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text:
|Ziemer, Cherie
|Sharp, Richard
|Stern, Marshall
|Cotta, Michael
|Whitehead, Terence
|Stahl, David
Submitted to: Conference on Rumen Function
Publication Type: Abstract Only
Publication Acceptance Date: 11/16/1995
Publication Date: N/A
Citation: N/A Interpretive Summary:
Technical Abstract: Small subunit (SSU) rRNA was extracted from samples taken from the rumen (daily for 4 d) and directly from fermenters (daily, from 96 to 168 h of operation). Samples were hybridized to radiolabeled SSU rRNA-targeted DNA oligonucleotide probes which targeted total SSU rRNA, bacteria, eucarya, archaea, Fibrobacter genus, F. succinogenes, F. intestinalis, and two F. succinogenes subgroups. Data were analyzed using General Linear Models procedures of SAS. Single degree of freedom contrasts compared ruminal and fermenter samples. Expressing population data as a percentage of total SSU rRNA, ruminal samples had higher eucarya (52.23% vs 1.83%), lower bacteria (48% vs 84.4%) and archaea (1.32% vs 2.11%) than fermenters. While there were no differences between ruminal and fermenter samples for Fibrobacter (2.60%), F. succinogenes was lower (.47% vs .92%) and F. intestinalis was higher (.05% vs .01%) in ruminal samples compared with fermenter samples. F. succinogenes subgroup 1 was higher (.53% vs .18%) and subgroup 3 was lower (.81% vs 1.41%) in the rumen compared with fermenters. With the exception of protozoa, continuous culture fermenters supported a diversity of key ruminal populations comparable to that found in the rumen environment.


text:
Riot Games • Page 3
Uncharted 3 game director Justin Richmond leaves Naughty Dog for Riot Games
Uncharted 3 game director Justin Richmond has left Naughty Dog for League of Legends developer Riot Games.
League of Legends Team Builder is out of beta and ready for you to queue
Riot Games has announced Team Builder for League of Legends is out of beta and "here to stay." The queue was designed to help members nominate their chosen role, champion and position before joining a team. Plenty of information on Team Builder can be found through the link. Thanks, TenTonHammer.
League of Legends betting scandal errupts after player attempts suicide
A former professional League of Legends player from South Korean, after exposing a match-rigging scandal he'd "unwittingly become a part of" is in critical condition after attempting suicide.
League of Legends introduces Team Builder queue
League of Legends is most fun when you're playing with a good crew, who know how to fill the various roles essential for victory. Riot Games has introduced a new kind of queue designed to help enable that kind of play, even when you're matchmaking with strangers.
Vel'Koz is the latest League of Legends champion to be spotlighted
Vel'Koz is the latest League of Legends champion to be spotlighted, and the creature is a Void beast which "kills to learn and learns to kill." Also known as the Eye of the Void, Vel'Koz is a ranged champion which makes use of Plasma Fission, Void Rift and Tectonic Disruption. Repeated attacks will build up […]
League of Legends attracts 27 million players each day
League of Legends developer Riot Games has quietly announced an almost ridiculous new set of usage statistics, including word that the free-to-play MOBA brings in 27 million players every single day.
League of Legends will hopefully last "decades" says Riot
League of Legends developer Riot Games has discussed the longevity of its popular MOBA, and compared eSports' biggest hitters to long-standing physical sports, suggesting that the game could last decades.
League of Legends updates blocked by UK's anti-porn filter - report
League of Legends fans have reported difficulties downloading updates for the game thanks to the UK's new and apparently over-eager anti-porn filter.
League of Legends: Little Wraith team members handed ban after server crackdown
League of Legends pro team Little Wraith's players have been hit with bans just a couple of months after qualifying for the Intel Extreme Masters Regional Invitational. Riot Games has since responded to the matter.
League of Legends - new players to receive a "static roster of free champions" for first few levels
League of Legends will be easier for new players to get into, thanks to a free batch of champions Riot Games will unlock in a future update.
League of Legends patch 4.1 is about "refinement and retuning," contents discussed
League of Legends developer Riot Games has shed light on its 4.1 patch. Find out what's what in here.
Former WoW lead systems designer Greg Street joins Riot Games
Greg "Ghostcrawler" Street, who was lead systems designer on World of Warcraft until he announced in November he was leaving the firm to pursue a "great opportunity for something new and exciting" has joined League of Legends developer Riot Games. The news popped up on his LinkedIn resume, and was posted by Reddit. Before his […]
Battle.net & League of Legends services down, following DDoS attacks
Battle.net and League of Legends services have been taken down by DDoS attacks, following a similar assault on Steam and EA's Origin store.
Riot all about building "engagement", not "money hungry" ARPU metrics - Merrill
League of Legends developer Riot Games doesn't focus on revenue metrics, preferring to believe that if it builds a great game, money will just turn up, according to president and co-founder Marc Merrill.
League of Legends: "non-essential" EU updates on hold to ensure stability over the holidays
League of Legends developer Riot Games has placed all of the the MOBA's non-essential updates on hold until January, to ensure server stability over the holidays.
League of Legends update 3.15 adds Yasuo, patch notes inside
League of Legends developer Riot Games has released patch notes for its 3.15 update, which is rolling out today from 7:30 am PST. It adds new champion Yasuo and the usual barrage of gameplay tweaks and balancing.
League of Legends pro streaming bans lifted
Riot Games has elected to change policies on professional League of Legends players' streaming activities following negative community reaction.
League of Legends pros banned from streaming competing titles
League of Legends players who sign on to professionally in Season Four are contractually obliged not to livestream gameplay sessions of competing products.
League of Legends adds Yasuo the Unforgiven to its roster
League of Legends has added a new champion its roster, and its Yasuo the Unforgiven. The close-combat melee character packs around a samurai sword and various skills such as: Way of the Wanderer, Steel Tempest, Wind Wall, Sweeping Blade, and Last Breath. You can read up on the character more through the latest LoL blog […]
League of Legends Season 3 World Championship had over over 32 million viewers
Riot has announced that over 32 million people watched the League of Legends Season 3 World Championship finals in October.
Riot Games latest
League of Legends introduces Team Builder queue, will enter beta servers soon
League of Legends' latest champion is the "loose cannon" Jinx
League of Legends minion XP bug being fixed by Riot Games today
EVE Online lead designer joins Riot Games to work on League of Legends
League of Legends' female characters banned in Iranian tournament
League of Legends hacked, encrypted credit card details compromsied
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Drugs for the Treatment of Parkinson's Disease
Volume 88 of the series Handbook of Experimental Pharmacology pp 307-323
Anticholinergic Drugs and Amantadine in the Treatment of Parkinson's Disease
- A. E. Lang
- , R. D. G. Blair
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Anticholinergics and amantadine both result in mild to moderate improvement in Parkinson's disease. These drugs still have an important role to play in the treatment of the disease despite the greater clinical effects of levodopa and dopamine agonists. They may be used either as monotherapy or as adjunctive treatment. Benefit can be obtained in all stages of the disease, but it is typically most noticeable early on when disability is less marked. Many neurologists utilize these drugs initially in hopes of delaying the need for levodopa and later to permit the use of lower doses of this agent because of increasing concern that early treatment with levodopa may create many of the long-term problems faced in the later stages of the disease. In this chapter we will review anticholinergic and amantadine treatment of Parkinson's disease, emphasizing the proposed mechanisms of action, what is known of the pharmacokinetics, the clinical effectiveness and side effects.
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- Title
- Anticholinergic Drugs and Amantadine in the Treatment of Parkinson's Disease
- Book Title
- Drugs for the Treatment of Parkinson's Disease
- Pages
- pp 307-323
- Copyright
- 1989
- 10.1007/978-3-642-73899-9_12
- Print ISBN
- 978-3-642-73901-9
- Online ISBN
- 978-3-642-73899-9
- Series Title
- Handbook of Experimental Pharmacology
- Series Volume
- 88
- Series ISSN
- 0171-2004
- Publisher
- Springer Berlin Heidelberg
- Copyright Holder
- Springer-Verlag Berlin Heidelberg
- Additional Links
- Topics
- Industry Sectors
- eBook Packages
- Editors
- Editor Affiliations
- 1. Division of Neurology, UBC Health Sciences Centre Hospital
- Authors
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- Simon A. Levin, Princeton University, Department of Ecology and Evolutionary Biology, Dirk Brockmann, Humboldt-Universität zu Berlin, Department of Biology. Princeton-Humboldt Cooperation and Collective Cognition Network
- Jan-Werner Mueller, Princeton University, Department of Politics, Silvia von Steinsdorff, Humboldt-Universität zu Berlin, Department of Social Sciences. Constitutions Under Stress: Comparative Perspectives
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- Clifford P. Brangwynne, Princeton University, Department of Chemical and Biological Engineering, Simone Reber, Humboldt-Universität zu Berlin, Quantitative Biology, Sabine Petry, Princeton University, Department of Molecular Biology. How to Shape Living Structures - Mesoscale Self-Organisation of Non-Membrane Bound Cellular Structures
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S1: Paralympic Injuries
Video duration: 3:21Video has closed captioning.
Cheri Blauwet, seven-time Paralympic medalist and now a medical doctor, talks about injuries, athlete classifications, and doping controls. "I loved competing," she tells MEDAL QUEST, and she's proud to be working now to improve rights and health for all individuals with disabilities.


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I have 91 GMC Sonoma regular cab with a bench seat. I've been reworking everything to make it as I see fit and would really enjoy having a fold down arm rest. Is there any way to create a fold down arm rest in a bench seat? Or is there another seat that I could replace this with? This is my first time working with the seats of a vehicle. I'm not afraid to replace the bench with buckets if I had guidance in how to do so... Any help would be appreciated.
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