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Due to Brad Arnold��s recent bout of laryngitis, 3 Doors Down regretfully announce some changes to their forth coming European dates.�� In order to facilitate a smooth and full recovery for frontman Arnold, doctors have advised the band to refrain from playing too many shows in a row as they return to the road in Europe.
To accommodate the doctors�� orders, these shows have been cancelled:
Thursday 16th October 2008 Wulfrun Hall, Wolverhampton, UK �� CANCELLED
Tuesday 28th October 2008 Zenith, Munich, Germany – CANCELLED
Wednesday 5th�� November 2008 Tradgarn, Gothenborg, Sweden�� CANCELLED
The following date is moved from Friday 24th October to the following
Wednesday 29th�� October 2008 Stadthalle, Offenbach, Germany �� RESCHEDULED
For the rescheduled date, original tickets remain valid. People with tickets for cancelled shows should contact their point of purchase for refunds.
BradArnold �� "I just want to say that I��m very sorry to have to cancel these European shows. We have been touring relentlessly and it just finally caught up with me.�� I apologize to all the people who have tickets for these shows and promise we��ll make it up to you. Thanks very much for your understanding and support��
All other dates on the European tour through Octoberand November 2008 remain the same.
The band is touring to support the recent release oftheir self-titled, fourth studio album through Island Records.�� �� The album debuted at #1 on the BillboardTop 200 Chart in May, 2008, and has remained on the charts while the bandcontinues to tour behind its success.��
For furtherInformation:
�� ��Taut musicianship, well-crafted songs and potent vocals make this a landmark album in an already multiplatinum career.�� �� Billboard review of latest album ��3 Doors Down��
�� ��Taut musicianship, well-crafted songs and potent vocals make this a landmark album in an already multiplatinum career.�� �� Billboard review of latest album ��3 Doors Down��


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ZPT-9-FRM Floor Outlet Round PVC Support Frame Accessory
This is the frame to mount an outlet to, then in turn, glue onto the ZPT-9-CAN electrical conduit box when the final floor height is known.
Works with our Victorian Design Floor Outlet Cover Plates.
Frame Measurements:
Made of high impact thermoplastic PVC. Suitable for concrete, wood or carpeted floors.
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Vintage Hardware & Lighting ~ 2000 W Sims Way ~ Port Townsend, WA 98368 ~ 360-379-9030
Vintage Hardware, Vintage Lighting, and Vintage Hardware and Lighting are Registered Trademarks. - All rights reserved.
© Vintage Hardware & Lighting 1999-2017
We reserve the right to change or modify policies, prices, sizes, and/or designs at anytime, without prior notification.

subset: commoncrawl


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Contact us 24/7: +1 877 678 9627
View product details
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- - True to size
- - Fitted design
- - High-waisted style
- - Model is 177cm/ 5'10" and is wearing a size XSmall
The FW11 runways were alive with bold polka dot motifs and Marc Jacobs led the pack with his ladylike yet playful approach. Emulate the statement runway look and team this wool-fleece pencil skirt with the matching top and leather boots.
Shown here with: DANNIJO ring, Michael Kors shoes, Jimmy Choo clutch.
- Marc Jacobs high-waisted pencil skirt: black and white polka dot stretch wool-fleece, elasticated waist band, back vent. Back zip fastening. 93% fleece wool, 7% polyester. Dry clean.
Product Code: 169749
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text:
Far Cry 3 – Review
Far Cry 3 demands your attention like a flare in a black night. Read More>>
ZombiU – Review
An excellent day one example of the Wii U's twist on gameplay. Read More>>
Assassin's Creed 3 – Review
Assassin's Creed 3 survives its continental transplant with flying red, white and blue colours. Read More>>
News & Gossip / PC/Mac / Playstation 3 / Wii U / Xbox 360
Ubisoft and New Regency to partner for Assassin's Creed film
Attachment of actor Michael Fassbender to project confirmed. Read More>>
Assassin's Creed 3: Liberation story trailer released
Assassin's Creed Cajun style. Read More>>
ZombiU – Hands On Preview
We come away suitably impressed with Ubisoft's bespoke Wii U zombie title. Read More>>
PC/Mac / Playstation 3 / Previews / Wii U / Xbox 360
Assassin's Creed 3 – Hands On Preview
At home on the range, where the deer and the antelope play. Read More>>
Watch Dogs – Preview
Sadly, not a videogame reprisal of Anne Robinson's customer complaints show. Shame we say, shame! Read More>>
Assassin Creed 3′s amazing grace unveiled in latest trailer
A brief glimpse of war on the high seas as well as the familiar acrobatics of AC's land-based heroics Read More>>


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The new YZ250F… designed specifically for the 250cc class competition.
Introducing the new 2010 Yamaha YZ250F. The key development concept behind this awesome new machine is excellent cornering and handling performance. In other words, the new 2010 YZ250F "does exactly what the rider wants".
The year was 2001 and Yamaha introduced the first modern 250cc 4-stroke motocrosser. We have taken the original concept of "Ultimate Quick Turn Performance" and elevated it to an entirely new level.
The all new Bilateral Beam aluminum frame centralizes mass for exceptional cornering and handling performance. The 250F is more compact than the pervious generation chassis for superior cornering. The optimized engine delivers a new level of power in the low-to-midrange, with a great torquey feel, exactly where riders want it. Mix in improvements to the intake and exhaust system, lighter valve train, new carburetor settings and you have a winning combination that will be hard to beat.
Key Features
• The all-new, Bilateral Beam frame is specific to the 250 and is more compact than the previous generation chassis. This places the rider closer to the front wheel, which delivers superb rigidity balance for unmatched lightweight handling and cornering. This nimbleness lets the rider get on the gas sooner out of corners and cross the finish line with less fatigue – even on long motos.
• The optimized engine delivers a new level of power in low-to-midrange, with a great torquey feel, exactly where riders want it. That is due to the new straight intake boot that enhances breathing, new carburetor that provides excellent throttle response and fuel atomization, and redesigned valve train components that reduce inertial mass and boost low end torque. Exhaust is also enhanced with a new D-shaped exhaust port and newly designed exhaust system. Ongoing refinement to the suspension and engine produces an amazingly balanced, light-handling machine with performance that's accessible to all levels of riders.
• All new styling emphasizes the bike's light weight and nimble handling character. The sharp, horizontal lines set the bike apart, with a clean, aggressive look.
KYB® suspension has been recalibrated front and rear and is tuned to work with the new Bilateral Beam frame for unmatched handling. The clutch lever has a lighter pull feel even though the clutch has stronger engagement. The new clutch also has a wider engagement range that will give riders an advantage off the line. . . shift after shift, moto after moto.
• There's no disputing the YZ250F's unmatched four-stroke prowess – it was the 1st four-stroke 250 motocross bike on the market, the 1st to win an international race, the 1st to win an AMA® Supercross ® and the 1st to take an AMA® U.S. Supercross Championship® title, as well as the first to win an AMA® National race.
Features and Benefits
• For 2010 the YZ engineers have focused on optimizing the intake & exhaust systems, lightened the valve train, revised the carburetor settings and improved the ignition advance characteristics. These improvements result in improved low to mid power and a more rider friendly engine with a more linear power delivery for improved drivability and control.
• New, liquid-cooled, 250cc, DOHC, 5-titanium valve, 4-stroke engine features a 13,500-rpm redline.
• Short skirt forged piston reduces weight and vibration, plus offers excellent durability.
• The 13.5:1 compression ratio provides fast, controlled combustion and excellent engine performance.
• Optimized 5-valve (3-intake & 2-exhaust) combustion chamber design provides the most efficient intake and exhaust flow for maximum power.
• Titanium valves decrease weight by more than 40% over a conventional steel valve train and reduce reciprocating mass for faster-revving.
• All new aluminium valve retainers reduce inertial mass for faster throttle response
• New "load reduced" valve springs reduce the amount of force required to open the valves and thereby minimizes power losses associated with friction and improves torque in the low and mid ranges.
• Special chromium nitride coating on the tips of the intake valve stems reduces wear.
• Exhaust port shape has been revised from a round to a "D" shape to optimize flow and improve performance and engine character
• Revised intake cam profile further improves performance.
• The lightweight "liner less" aluminium cylinder features a ceramic composite coating which insures faster, more uniform heat dissipation, reduced friction and a longer service life.
• Cylinder design features cutaways that allow the air trapped under the piston to enter a side chamber (or cutaway) to reduce horsepower-robbing "pumping losses."
• Revised lightweight engine crankcase also utilizes special cutaways to reduce "pumping losses." The crankcase cutaways match the cutaways in the cylinder for maximum efficiency.
• Relocated convenient oil sight glass window and oil drain plug.
• Lightweight magnesium cylinder head cover.
• Dry sump lubrication system uses a remote oil tank reservoir positioned in front of the engine. This revised oil tank is lighter and more compact for 2010 and features a partition in the centre of the tank that improves the air-oil separation function. This tank is positioned low in the chassis which centralizes mass and lowers the centre of gravity for exceptional handling and a light feeling.
• Oil volume in the engine has been optimized to reduce weight and "oil drag" related power losses.
• Revised, 5-speed transmission features "involute splines" on the transmission axles to ensure smooth shifting and instant hook-up under power. The gear ratios for 3rd and 4th gears and the engagement dog shape have been changed to maximize the engine improvements. 3rd gear ratio = 26/18(1.444) while 4th gear ratio is 22/18(1.222).
• Lightweight engine counterbalancer reduces vibration for improved rider comfort and less rider fatigue.
• Revised multi-plate wet clutch features a revised clutch boss insert for improved wear, clutch spring load has been increased and the length of the push lever cam has been revised to change the lever ratio for an easier clutch lever pull and improved clutch feeling.
• Lightweight, "quick-access" outer clutch cover provides fast, easy access for clutch maintenance.
• Compact design automatic cam chain tensioner reduces maintenance and mechanical engine noise
• Revised Keihin FCR-MX37 flat-slide carburetor with throttle position sensor (TPS). The carb settings have been revised to accentuate the improvements in the intake and exhaust systems. The cam for the accelerator pump has been optimized while the shape of the carburetor "throat" on the air box side has been modified for improved air flow.
• The air box assembly has been revised for improved performance. The funnel shape at the air box "outlet" is optimized, while an all new straight design "boot" between the air box and the carb also improves air flow.
• Washable, dual-stage, foam air filter.
• No fuss auto decompression system means fast, easy starting. The YZ250F restarts in any gear.
• Convenient, handlebar-mounted hot start lever ensures fast starts when the engine is hot.
• Revised CD ignition system delivers a precise spark and monitors engine rpm to insure optimal timing for fast, strong response at all rpms. The ignition timing advance curve has been revised for improved performance.
• Direct ignition system means the ignition coil is integrated into spark plug cap to reduce weight and complexity.
• New compact, lightweight, single core, dual radiators provide outstanding cooling efficiency. The location of the rads has been lowered and moved rearward for improved performance and protection while also lowering the all important center of gravity and centralizing mass. The thickness of the cores has also been increased. For 2010, the revised rads mount to the new frame at 3 points.
• Lightweight titanium exhaust header pipe reduces weight, improves performance and allows hassle-free replacement of the oil filter.
• The lightweight exhaust system utilizes a 4-stage expansion format that improves the cylinder filling induced by the exhaust pulse effect, resulting in excellent power characteristics.
• Revised rigid mount muffler assembly is 50mm longer than last year for improved performance and reduced noise levels. The size of the internal diffuser pipe and the noise reducing "punched hole pipe" have been modified to achieve optimum performance.
• The muffler can be repacked to maintain peak performance and reduced noise. The lightweight aluminium / stainless steel muffler complies with current CMRC & AMA noise regulations for 2010.
• Trick, oversized "barrel adjuster" on the clutch lever perch allows on-the-fly clutch adjustments.
• All new, compact "bilateral beam" aluminium frame centralizes mass for exceptional handling and cornering ability. This 250cc class specifically designed frame consists of forged, extruded and panel aluminium parts. This all new frame is more compact than the last generation and offers significantly improved "rider – machine communication" (a.k.a. feedback). The key goal of this new chassis is faster and easier cornering … one of the keys to winning races.
• The engineers started with a clean sheet of paper and designed the chassis based on the requirements of a 250cc motocrosser. Note: the YZ250F frame is unique unto itself.
• The rigidity balance of this new frame has been optimized and features increased lateral and torsional rigidity compared to the last generation frame. It also contributes to a feeling of lightness, agility and traction.
• The head pipe (steering head), wheelbase, caster and trail dimensions are optimized to accentuate the new engine and frame character. The benefit is incredible turning ability and quick, stable handling.
• New removable rear sub frame is constructed of square-section, lightweight aluminium pipe. Its detachable design allows easy access when servicing rear suspension components.
• Lightweight, tapered, aluminium swingarm is produced using "hydro forming", a special method that uses high pressure water to form shapes. The swingarm design provides great overall chassis "balance" for precise cornering and a light handling feel.
• Forged aluminium upper triple and lower triple clamps reduces weight and improve strength.
• Pro Taper handlebars are one of the most sought after style of bars. The Pro Taper bars provide excellent strength and durability. Foam handlebar pad is included.
• Handlebar position has been raised 5mm for 2010 to suit the new, more compact frame. The revised handlebar holders (with the upper triple clamp), offer a total of 4 different positions, and an adjustment range of 30mm, to better suit a wide variety of riders.
• Revised 48mm, adjustable, inverted, Kayaba cartridge fork features a twin-chamber design. The twin chamber design means the damper unit is in a separate structure which prevents aerated fork oil from entering the inner damper assembly and degrading its damping abilities. Since the inner damper is pressurized, it also prevents air bubbles forming in the oil. Front fork adjustments include: 20-way compression damping and 20-way rebound damping.
• Optional fork springs are available through Genuine Yamaha parts.
• Fork damping settings have been revised for 2010. The shape of the outer fork tubes, the inner piston rod design, and the low friction fork oil seals are also revised. The engineers focused on the enhancing the ground holding capabilities of the front wheel, a key for precise cornering.
• The 48mm inverted KYB fork also features a Transfer Control Valve (TCV) system. The TCV enhances the damping force of the inner damper from mid stroke to full stroke and improves bottoming characteristics. The benefit of TCV is more precise control throughout the full stroke. The TCV is located on the upside of the spring and its function is controlled by piston speed, not piston position … hence the term "Speed Sensitive fork".
• Front wheel travel is 300mm or 11.8″
• Revised, large "wrap-around" plastic fork protectors provide excellent lower fork tube protection. The "self-supporting" design reduces friction for smoother fork operation.
• Revised Monocross link rear suspension system features a fully adjustable Kayaba, piggyback shock which features separate adjusters for high- and low-speed compression damping. Adjustments include: spring preload, 20-way rebound damping, 20-way low-speed compression damping and 2 turns of high speed compression damping.
• The shock spring location has been lowered 29mm to accommodate the new intake boot.
• The shock uses an 18mm diameter piston rod. Kashima coating is used in the shock body and sub tank to reduce friction and improve suspension performance during a long moto. The Kayaba shock utilizes a full rebound oil lock system for excellent suspension function and great ride quality.
• Rear wheel travel is 307mm (12.1″).
• 250mm floating front wave-style disc reduces weight and is squeezed by a Nissin twin piston caliper.
• 245mm rear disc brake features a lightweight "wave-style" disc and a single piston Nissin caliper.
• Compact and lightweight rear master cylinder is an integrated design (fluid reservoir is integrated into the top of the master cylinder) for strong stopping power with excellent feel and control.
• Newly designed rear pedal tucks in tighter to the engine / frame and reduces weight.
• Newly designed, compact body work includes front number plate, front fender, rad shrouds, fuel tank, side panels and rear fender
which enhance the lightweight feel and look of the new YZ250F. This new "minimal " bodywork is a flat design, allowing fast, easy rider movements. The ergonomics provide a natural and roomy riding position. The body has been designed to maintain it good looks throughout the life of the machine.
• The lightweight, plastic resin 6.4 litre fuel tank compliments the chassis and has been moved closer to the rider for centralization of fuel tank mass and compactness.
• Redesigned seat is unique to the 250F. The surface texture has been designed to give a grip when needed, yet still allow easy rider movements. The "gripper" style seat cover has been designed to resists clogging with dirt or mud to ensure long lasting good looks.
• New lightweight Sun Star rear sprocket.
• Lightweight, 21″ front and 19″ rear Excel rims provide exceptional durability and help reduce unsprung weight for optimal suspension performance and handling.
• Rear wheel assembly uses a large 25mm diameter axle and a rear hub design which features a second bearing on the sprocket side for increased rigidity and durability.
• Bridgestone knobby tires offer competition-spec traction and excellent wear. Front = M403 / rear = M404.
• All new rugged polypropylene engine and integrated water pump protector plate reduces weight.
• "Shorty" adjustable front brake lever. Adjustment range is 5.5mm.
• New heavy duty plastic rear caliper and lower rear disc protectors.
• Large fuel cap and filler hole ensures easy opening and fast, hassle-free refuelling.
• New lightweight, extra wide foot pegs are 5mm higher and provide excellent grip and improved rider comfort.
• Lightweight header pipe heat shield.
• Serrated rear brake pedal for extra grip.
• Folding gear shifter tip.
• Stainless steel inner clutch cable provides excellent strength and durability.
• Lightweight chain guide / support helps reduce chance of chain derailment. It also helps protect rear sprocket from damage too.
• Heavy duty rubber swingarm protector.
• Heavy duty DID 520 drive chain.
USA Specifications
MSRP*$7,090 (White/Red) Available from September 2009
$6,990 (Team Yamaha Blue/White) Available from September 2009
Type: 250cc liquid-cooled DOHC 4-stroke; 5 titanium valves
Bore x Stroke: 77.0mm x 53.6mm
Compression Ratio: 13.5:1
Fuel Delivery: Keihin® FCR MX37
Ignition: CDI
Transmission: Constant-mesh 5-speed; multiplate wet clutch
Final Drive: Chain Drive
Suspension/Front: Speed-Sensitive System inverted fork; fully adjustable, 11.8-in travel
Suspension/Rear: Fully adjustable single shock; 12.0-in travel
Brakes/Front: Hydraulic single disc brake, 250mm
Brakes/Rear: Hydraulic single disc brake, 245mm
Tires/Front: 80/100-21
Tires/Rear: 110/90-19
Dimensions Length: 85 in
Width: 32.5 in
Height: 51.3 in
Seat Height: 38.9 in
Wheelbase: 57.7 in
Ground Clearance: 14.8 in
Wet Weight: 224.8 lb
Fuel Capacity: 1.7 gal
Warranty: 30 Day (Limited Factory Warranty)
For discussion on the Yamaha YZ250F or on Yamaha Motorcycles clink on link.


text: My husband is over 10 years older than me. This means he is over 40. I am curious if this could cause some fertility issues once we start preparing for a child. Is there any concern? Is there anything that may help to ensure we will have a child? Suggestions needed.


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Snowman Prep Bowl Set of 3
Holiday bakers unite with fun holiday themed bowls for baking and entertaining!
This is perfect for under a coat or if the wind isn't blowing wear it alone. Rule one ALWAYS WEAR A ZIP UP! If you wear a pull-over you will regret it. There will be snow everywhere and most likely down the back of your shirt.
When you are inside: Pair with an oversized sweater (perhaps your bf's?) When you are outside: Hide them under some jeans or yoga pants. Either way they will keep you warm and dry!
This ornament reminds me of Christmas at my grandparent's house deep in the woods outside Little Rock, Arkansas. Sitting by the fire watching the wildlife outside. Just simple peace and quiet and sometimes a little snow.
a chubby snowman to help you get chubby over the holidays!
This is a fun platter for a cheese ball and crackers. When the cheese ball has been eaten, there is a fun little scene to be enjoyed!Tags: entertaining, snow, platters, serving trays, holiday, Christmas, snowmen, fabulous, chuckAdded 10 Years Ago from Target


text: There will be a special Halloween show of Hotel Transylvania at the Charlestowne 18 Theatre. Come dressed in your Halloween costume and join us Saturday, October 26th at 10:00 a.m. This event is Free and is sponsored by the St. Charles Bank & Trust Company. Hotel Transylvania: Welcome to the Hotel Transylvania, Dracula's lavish five-stake resort, where monsters and their families can live it up, free to be the monsters they are without humans to bother them. Dracula has invited some of the world's most famous monsters to celebrate his daughter Mavis's 118th birthday. For Drac, catering to all of these legendary monsters is no problem, but this could come crashing down when one ordinary guy stumbles on the hotel and takes a shine to Mavis.


text:
Little Girl Cheers on Gator Cheerleaders
Published January 21st, 2011
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Aubree Ford is a little girl of many interests. But at five years old, most of her passion is seen rooting for the people who cheer on the Gators. She knows every cheerleader by name, knows most of their majors, and even their injury history. But Aubree has a physical ailment of her own. It's not keeping her down from her cheerleading dream, and instead is acting as a fuel for Aubree's determination and desire to overcome, no matter what the obstacle.
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- Tebow's First Run Draws Cheers From Jags Fans
- Ninja Cheers Are Plentiful For Aja Paculba
- 12th Annual Little House Gator Homecoming Parade


text:
hi all ,, hope u doing gd and having gd time ..
i was using bt4r1 and wanted to update it to r2 i followed the steps that are mentioned here Upgrading - BackTrack Linux
and when i reached the step fix-splash ,,, i restarted the pc ,, logged in,,typed startx
then it tells me that there is a problem and no screen found :S
any idea guys ???
and another question .. could we see a new release of backtrack soon ?


text:
Comparison of GSK134612 in Subjects Previously Vaccinated Against Meningococcal Disease Versus Non-vaccinated Subjects
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
In this study, subjects who were vaccinated with a meningococcal polysaccharide vaccine in a previous study (whose objectives & outcome measures are presented in a separate protocol posting with NCT number = 00227422) will be vaccinated with a new vaccine using conjugation technology.
These subjects will be compared to subjects vaccinated with the new vaccine, but who were not previously vaccinated with a meningococcal polysaccharide vaccine.
|Infections, Meningococcal
|Biological: Meningococcal vaccine GSK134612
|Phase 2
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Prevention
|Official Title:
|Immunogenicity & Safety Study of GSK Biologicals' Meningococcal Vaccine GSK134612 Administered in Healthy Subjects Either Previously Primed With Mencevax™ ACWY or naïve to Meningococcal Vaccination.
- Meningococcal rSBA titres [ Time Frame: One month post-vaccination ]
- Meningococcal rSBA titres [ Time Frame: Prior to vaccination ]
- Anti-meningococcal polysaccharide concentrations [ Time Frame: Prior to and one month post-vaccination ]
- Anti-tetanus toxoid antibody concentrations [ Time Frame: Prior to and one month post-vaccination ]
- Vaccine response to meningococcal antigens [ Time Frame: Prior to and one month post-vaccination ]
- Occurrence of solicited local and general symptoms [ Time Frame: Day 0 to Day 3 post-vaccination ]
- Occurrence of unsolicited symptoms [ Time Frame: Up to one month post-vaccination ]
- Occurrence of Serious Adverse Events [ Time Frame: Day 0 to study month 6 ]
- Occurrence of specific adverse events of rash, new onset of chronic illness(es), conditions prompting ER visits and/or any event related to lack of vaccine efficacy (i.e. documented meningococcal disease [ Time Frame: Day 0 to study month 6 ]
|Study Start Date:
|May 2008
|Study Completion Date:
|June 2009
|Primary Completion Date:
|December 2008 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: MPS
Subjects who were vaccinated with Mencevax™ ACWY in a previous study
Biological: Meningococcal vaccine GSK134612
one dose, as intramuscular injection
Experimental: noMPS
Subjects who were never vaccinated with a meningococcal vaccine (or not in the previous 10 years)
Biological: Meningococcal vaccine GSK134612
one dose, as intramuscular injection
Detailed Description:
GSK Biologicals has developed a meningococcal conjugate vaccine (GSK134612). This candidate vaccine has been shown to be well tolerated and immunogenic in toddlers, children aged 3-5 years, and adolescents/young adults. Repeated vaccinations with unconjugated meningococcal polysaccharide vaccine has shown to induce hyporesponsiveness to re-vaccination, this for serogroup C, and a recent publication suggest the same may be true for other serogroups.
This study will evaluate GSK Biologicals' candidate vaccine's ability to induce satisfactory immune response for the serogroups it contains across subjects 4.5 through 34 years of age who previously received a tetravalent meningococcal polysaccharide vaccine when aged 2-30 years. A non-randomised age-strata matched group of subjects, who have not previously received (or not received within the preceding 10 years) any meningococcal vaccine, will also be administered the GSK134612 vaccine for comparison.
|Ages Eligible for Study:
|4 Years to 34 Years (Child, Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Only subjects who the investigator believes that they and/or their parents/guardians can and will comply with the requirements of the protocol should be enrolled in the study.
- For the MPS group, a male or female between, and including, 4.5 and 34 years of age at the time of the study vaccination, who has been vaccinated in GSK Biologicals' study 102394.
- For the noMPS group, a male or female between, and including, 4.5 and 34 years of age at the time of the study vaccination.
- Written informed consent obtained from the subject/ from the parent or guardian of the subject.
- Healthy subjects as established by medical history and clinical examination before entering into the study.
- Previously completed routine childhood vaccinations to the best of his/her knowledge.
- If the subject is female, she must be of non-childbearing potential, or if she is of childbearing potential, she must practice adequate contraception for 30 days prior to vaccination, have a negative pregnancy test and continue such precautions for 2 months after completion of the vaccination series.
Exclusion Criteria:
- Use of any investigational or non-registered product (drug or vaccine) other than the study vaccine within 30 days preceding administration of the study vaccine, or planned use during the complete study period (active phase and extended safety follow-up).
- Chronic administration (defined as more than 14 days) of immunosuppressants or other immune-modifying drugs within six months prior to the study vaccine dose.
- Planned administration/ administration of a vaccine not foreseen by the study protocol within 30 days of administration of the study vaccine and up to 30 days after the study vaccine.
- Concurrently participating in another clinical study, at any time during the study period (active phase and extended safety follow-up), in which the subject has been or will be exposed to an investigational or a non-investigational product (pharmaceutical product or device).
- For the MPS Group, vaccination against meningococcal disease after completion of study 102394
- For the noMPS group, previous vaccination, or vaccination within the last 10 years, against meningococcal disease (of any serogroup).
- Previous vaccination against tetanus within 30 days.
- History of meningococcal disease.
- Any confirmed or suspected immunosuppressive or immunodeficient condition, including human immunodeficiency virus (HIV) infection, based on medical history and physical.
- A family history of congenital or hereditary immunodeficiency, unless the child has previously been documented, through laboratory testing, to have normal immune function.
- History of reactions or allergic disease likely to be exacerbated by any component of the vaccine.
- Know hypersensitivity to any component of the vaccine.
- Major congenital defects or serious chronic illness.
- History of seizures (this criterion does not apply to subjects who have had a single, uncomplicated febrile convulsion in the past) or progressive neurological disease.
- Acute disease at the time of enrolment
- Administration of immunoglobulins and/or any blood products within the three months preceding the first dose of study vaccine or planned administration during the active stage of the study period.
- Pregnant or lactating female.
- Female planning to become pregnant or planning to discontinue contraceptive precautions.
- History of chronic alcohol consumption and/or drug abuse.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00661557
|GSK Investigational Site
|Beirut, Lebanon, 1107-2020
|Study Director:
|GSK Clinical Trials
Additional Information:
Study Data/Documents: Informed Consent Form
For additional information about this study please refer to the GSK Clinical Study Register
For additional information about this study please refer to the GSK Clinical Study Register
For additional information about this study please refer to the GSK Clinical Study Register
For additional information about this study please refer to the GSK Clinical Study Register
For additional information about this study please refer to the GSK Clinical Study Register
For additional information about this study please refer to the GSK Clinical Study Register
For additional information about this study please refer to the GSK Clinical Study Register
|Responsible Party:
|ClinicalTrials.gov Identifier:
|NCT00661557 History of Changes
|Other Study ID Numbers:
|Study First Received:
|April 14, 2008
|Last Updated:
|September 9, 2016
|Individual Participant Data
|Plan to Share IPD:
|Plan Description:
|Patient-level data for this study will be made available through www.clinicalstudydatarequest.com following the timelines and process described on this site.
Keywords provided by GlaxoSmithKline:
Booster vaccination
Meningococcal vaccine
Meningococcal disease
Additional relevant MeSH terms:
Meningococcal Infections
Neisseriaceae Infections
Gram-Negative Bacterial Infections
Bacterial Infections
Immunologic Factors
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on June 23, 2017


text:
Andreas Whittam Smith With the markets in turmoil, the risk of deflation is high
In the UK and France, inflation is running at 0.2 per cent; Germany is at 0.3 per cent and the US at 0.5 per cent
In the UK and France, inflation is running at 0.2 per cent; Germany is at 0.3 per cent and the US at 0.5 per cent
Tech giant 'avoided' paying more than $1m every hour due to use of international loopholes
Crops from potatoes and peas to cereals are being hit, leading to increased reliance on imported produce
The BBC came under heavy criticism from its own trustees today after selling the Lonely Planet travel guides business to an American billionaire and making a loss of £80 million.
Irreversible changes in consumer behaviour, disruptive technologies, and recession are together destroying our High Streets. I know, send for the Queen of Shops!
Pilotless civilian aircraft could start to become a common sight in British skies within the next 10 years, it was claimed today.
HMRC chief denies turning blind eye to global giants avoiding massive UK tax bills
President François Hollande, facing an unprecedented meltdown in his popularity, today criticised the impatience of French voters but promised that his softly-softly approach would triumph in the end.
FIFA have vowed to keep empty seats to a "strict minimum" at the next World Cup.
The creator of Red Bull, who became one of the world's richest men thanks to the success of the fizzy, caffeine-laden drink, died yesterday in Bangkok of natural causes. Chaleo Yoovidhya was 89.
The Institute of Fiscal Studies was busy last week. First, the IFS calculated that the Government's public-sector pension reforms will not save the Exchequer any money.
Rising numbers of Chinese, Saudi and Brazilian retail tourists seeking heavily discounted, tax-free luxuries have contributed to soaring Boxing Day sales figures in London's West End.
They journeyed from the East to pay homage to the boy king bearing gifts of gold, frankincense and myrrh. But they would struggle to complete the feat today. Times for wise men have never been tougher. Gold prices are soaring on commodity markets, myrrh crops have been hit by drought – and now frankincense could soon be no more.
Cocoa farmers on the small African island of São Tomé in the Gulf of Guinea used to struggle to make a living. They were getting a very low price as they had to sell their cocoa by the roadside to middle men.
The film industry brought in billions of pounds to the UK economy last year but a cut to tax breaks could see growth collapse, according to a report from Oxford Economics.
French scramble to prop up prices as the world's biggest trader sells stock
Shadow Chancellor says safeguarding Britain's credit rating will be his priority


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My neighbors don't know. They might have guessed if they've seen me walk my pelican case to my car with my green ammo can, but I don't talk to them about it.
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My neighbors don't know. They might have guessed if they've seen me walk my pelican case to my car with my green ammo can, but I don't talk to them about it.
Come to think of it, my 80 acres is probably only a few steps away from being declared a compound.:smile:
In the sticks, I don't sweat it.
The neighbors across the street from me are hunters, NRA members, the homeowner is a CCW holder as well. So I have engaged conversation about certain things. We never say what we have or how much of this or that. We just know who can watch our back when the zombies walk down the street.
by the way, i am from Toledo OH, and going back there a few years ago...I would tell nobody that I had firearms. No offense but some of the area gave me bad vibes but I have no idea what neighborhood it was.
I don't hide it and I don't advertise it.
But... I sometimes do political ranting (pro 2A) on Facebook, so those folks must think I'm armed.
no. why advertise?
No they do not.
Only the closest neighbor (friend) knows the other don't need to know. I surely would not tell new people in the neighborhood. IMHO.
If two people know, it's not a secret. EDC night and day, 24/7.
No. Not ever. If asked it's a heart monitor.
Only the mailman suspects from my mail
The UPS guy knows...
UPS: "What's in this box, a load of bricks?"
Me: "No. 700 rounds of ammo."
UPS: :embarassed:
I had to repair my mailbox post after the mailman crammed 500 rounds of 230 LRNS in it.
I live in a small town in Alabama, I would bet that over 80% of the households have guns
Years ago we bought SA. All berdan primed. The ups guy was not happy!
Then several years later we got the Greek .06 not happy again
No ammo lately but they hate tires


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Hello I am doing a homework project. Can someone please give me an explantion of why the 10 precepts and the duties of monk will help you to gain enlightenment? and what are the benefits of each one
how is it like what the buddha did to gain to gain enlightenment


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