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Volume 623 of the series Methods in Molecular Biology pp 123-136
Strategies in Designing Multigene Expression Units to Downregulate HIV-1
- Jane ZhangAffiliated withBeckman Research Institute of City of Hope Email author
- , John J. RossiAffiliated withBeckman Research Institute of City of Hope
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The treatment of viral diseases such as HIV and HCV is limited by the genetic diversity of the viruses, especially when they are under the selective pressure of drugs. This problem holds true for gene-based therapies using RNAi in which there is evolution of drug-resistant strains under the discriminating pressure of treatment (1, 2). In a gene therapy setting for treatment of HIV, the incorporation of multiple effector molecules, targeting different viral and cellular sequences, can improve viral inhibition by substantially delaying the emergence of escape mutants (3-8). However, for short hairpin RNA triggers of RNAi, high levels of expression by strong Pol III promoters has led to cell toxicity, and even death in experimental animals (9, 10). Here, we describe a new combinatorial anti-HIV gene expression system allowing simultaneous expression of multiple RNAi effector units from a single Pol II polycistronic transcript. Our platform is suitable for the inclusion of any shRNA sequence and can be combined with other types of small RNA antiviral inhibitors.
Key wordsRNAi HIV-1 miRNAs siRNAs Polycistron
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- Title
- Strategies in Designing Multigene Expression Units to Downregulate HIV-1
- Book Title
- RNA Interference
- Book Subtitle
- From Biology to Clinical Applications
- Pages
- pp 123-136
- Copyright
- 2010
- 10.1007/978-1-60761-588-0_8
- Print ISBN
- 978-1-60761-587-3
- Online ISBN
- 978-1-60761-588-0
- Series Title
- Methods in Molecular Biology
- Series Volume
- 623
- Series Subtitle
- Methods and Protocols
- Series ISSN
- 1064-3745
- Publisher
- Humana Press
- Copyright Holder
- Springer Science+Business Media, LLC
- Additional Links
- Topics
- Keywords
- RNAi
- miRNAs
- siRNAs
- Polycistron
- Industry Sectors
- eBook Packages
- Editors
- Wei-Ping Min (ID1)
- Thomas Ichim (ID2)
- Editor Affiliations
- ID1. Dept. Surgery, Pathology & Oncology, University of Western Ontario
- ID2. MediStem Laboratories, Inc.
- Authors
- Jane Zhang (1)
- John J. Rossi (1)
- Author Affiliations
- 1. Beckman Research Institute of City of Hope, Duarte, CA, USA
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TMPRSS2 encodes a protein that belongs to the serine protease family. Additionally we are shipping TMPRSS2 Antibodies (67) and TMPRSS2 Kits (17) and many more products for this protein.
Showing 8 out of 12 products:
TMPRSS2-ERG (show ERG Proteins) role in prostate cancer invasiveness and regulation of MMP-9 (show MMP9 Proteins) and plexin B1 (show PLXNB1 Proteins).
Our results indicate that it is possible to predict pT3 stage at final histology from TMPRSS2:ERG (show ERG Proteins) gene fusion at initial core needle biopsy. FISH determination of TMPRSS2:ERG (show ERG Proteins) gene fusion may be particularly useful for patients scheduled to undergo a radical prostatectomy in order to improve oncological and functional results
Data show there was a good agreement of transcriptional regulator ERG (show ERG Proteins) protein (ERG (show ERG Proteins)) immunostaining with the presence of TMPRSS2:ERG (show ERG Proteins) fusion protein.
A combination of high preoperative serum PSA (show PLAG1 Proteins) and high expression of TMPRSS2-ERG (show ERG Proteins) could be promising in distinguishing those tumors that are aggressive and life-threatening.
Studies showed that urinary TMPRSS2:ERG (show ERG Proteins) transcripts seem to be indicative of Prostate cancer aggressiveness upon biopsy. [review]
Aspirin was associated with a significant reduction in the relative risk of TMPRSS2:ERG (show ERG Proteins) (T2E )fusion positive, but not T2E negative
the type II transmembrane serine protease (show TMPRSS11E Proteins) TMPRSS2 was able to activate hemagglutinin (show HA Proteins) for cell entry indicating that bat (show BAAT Proteins) influenza A virus can utilize human proteases for hemagglutinin (show HA Proteins) activation.
The relatively low rate of ERG (show ERG Proteins)-positive prostatic intraepithelial neoplasia counts in favor of the limited role of chimeric transcript TMPRSS2/ERG (show ERG Proteins) in the differential diagnosis of prostatic intraepithelial neoplasia
TMPRSS2 isoform 1 is expressed in viral target cells.
The TMPRSS2-ERG (show ERG Proteins) Gene Fusion Blocks XRCC4 (show XRCC4 Proteins)-Mediated Nonhomologous End-Joining Repair and Radiosensitizes Prostate Cancer Cells to PARP Inhibition
Genetic inhibition of TMPRSS2-ERG (show ERG Proteins) junction oncogene (show RAB1A Proteins) in prostate cancer by means of siRNA has strong antineoplastic effect in a mouse model and in vitro.
The androgen-regulated protease TMPRSS2 activates a proteolytic cascade involving components of the tumor microenvironment and promotes prostate cancer metastasis
TMPRSS2 as a host cell factor essential for viral spread and pathogenesis of mono-basic H1N1 and H3N2 influenza A viruses.
These results demonstrate that TMPRSS2 expression is essential for influenza A virus replication in vivo.
These data demonstrate that TMPRSS2 is a host factor that is essential for pneumotropism and pathogenicity of H7N9 and H1N1 influenza virus in mice.
Loss of TMPRSS2 serine protease (show F2 Proteins) activity does not influence fertility, reduce survival, result in prostate hyperplasia or carcinoma, or alter prostatic luminal epithelial cell regrowth following castration and androgen replacement.
This gene encodes a protein that belongs to the serine protease family. The encoded protein contains a type II transmembrane domain, a receptor class A domain, a scavenger receptor cysteine-rich domain and a protease domain. Serine proteases are known to be involved in many physiological and pathological processes. This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue. The protease domain of this protein is thought to be cleaved and secreted into cell media after autocleavage. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
, serine protease 10
, transmembrane protease serine 2
, plasmic transmembrane protein X

subset: commoncrawl


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text: Electronically Stored Information: The Complete Guide to Management, Understanding, Acquisition, Storage, Search, and Retrieval By David R. Matthews 2012 | 379 Pages | ISBN: 1439877262 | PDF | 7 MB Although we live in a world where we are surrounded in an ever-deepening fog of data, few understand how the data are created, where data are stored, or how to retrieve or destroy data. Accessible to readers at all levels of technical understanding, Electronically Stored Information: The Complete Guide to Management, Understanding, Acquisition, Storage, Search, and Retrieval covers all aspects of electronic data and how it should be managed. Using easy-to-understand language, the book explains: exactly what electronic information is, the different ways it can be stored, why we need to manage it from a legal and organizational perspective, who is likely to control it, and how it can and should be acquired to meet legal and managerial goals. Its reader-friendly format means you can read it cover to cover or use it as a reference where you can go straight to the information you need. Complete with links and references to additional information, technical software solutions, helpful forms, and time-saving guides, it provides you with the tools to manage the increasingly complex world of electronic information that permeates every part of our world. Buy Premium From My Links To Get Resumable Support,Max Speed & Support Me Code: Download ( NitroFlare ) http://nitroflare.com/view/377E1192E108D92/mouyt.E.S.I.R.rar Oboom https://www.xxxxxxxx/2K8J0DDR/mouyt.E.S.I.R.rar


text: SCHAUMBURG, Ill., March 21, 2013 /PRNewswire/ -- The Shelby Group, a leader in Procurement Optimization, announced today that Scott Dever has joined the company as Vice President of Sourcing Solutions. Mr. Dever will oversee Shelby's Sourcing Solutions business and lead the delivery of the Category Solutions offering, which helps companies achieve double-digit cost improvement and faster speed to savings across a wide range of indirect spend categories. Mr. Dever possesses an extensive background in the procurement industry. He has led global transformations for industry-leading brands resulting in broad-based change initiatives and breakthrough cost improvement. Mr. Dever joins the company from Xchanging plc where he was Executive Vice President and Managing Director for Procurement Services in the Americas. Prior to this, Mr. Dever held positions as Vice President of Procurement for Motorola, Chief Procurement Officer at Hewitt Associates, Vice President of Procurement and Strategic Sourcing at Sears Holdings, and Vice President of Global Procurement at Hasbro. "Over the past decade, Scott has achieved transformational procurement results for leading companies across multiple industries and various corporate cultures," said John Dreyer, President and CEO of The Shelby Group. "We are proud to have Scott as part of our leadership team." Mr. Dever said, "I am very excited to join The Shelby Group and to have the opportunity to work with such a talented team. I am particularly enthusiastic about our new Category Solutions offering, which will provide clients with cost improvement across a broad range of indirect spend categories. The combination of Shelby's technology-enabled process optimization expertise together with solid sourcing support creates a compelling value proposition for our clients." About The Shelby Group The Shelby Group leverages its deep understanding of enterprise procurement processes and technology to maximize savings and optimize business results throughout the procurement lifecycle. Whether you want to create sustainable procurement savings, maximize utilization of current tools, deploy or upgrade new software, move to the cloud, or outsource operations, partnering with Shelby pays off. To benefit from Shelby's experience in meeting the diverse needs of Fortune 500 clients and to learn more about what we can do to help optimize your success, call 312.445.8500. SOURCE The Shelby Group


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No country feels China's rise more deeply than Japan. Through intricate case studies of visits by politicians to the Yasukuni Shrine, conflicts at the East China Sea boundary, concerns about food safety, and strategies of island defense, Sheila A. Smith explores the policy issues testing the Japanese government as it tries to navigate its relationship with an advancing China. She finds that Japan's interactions with China extend far beyond the negotiations between diplomats to include a broad array of social actors intent on influencing the Sino-Japanese relationship. Some of the tensions complicating Japan's encounters with China, such as those surrounding the Yasukuni Shrine or territorial disputes, have deep roots in the postwar era, and political advocates seeking a stronger Japanese state organize themselves around these causes. Other tensions manifest themselves during the institutional and regulatory reform of maritime boundary and food safety issues. Smith scrutinizes the role of the Japanese government in coping with contention as China's influence grows and Japanese citizens demand more protection. Underlying the government's efforts is Japan's insecurity about its own capacities for change and its waning status as the leading Asian economy. For many, China's rise means Japan's decline, and Smith suggests how Japan can maintain its regional and global clout as confidence in its postwar diplomatic and security approach decreases.
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How To Discover A Reputable Driving School
The number of times have you dreamed of driving a car? Countless of times, for sure. So, why not learn to drive a car and deal with the controls from a driving instructor? You can also ask him why he's pushing those foot controls and why he keeps moving gears. By doing this, you will have a great idea how drivers do it and what each automobile control is for. Driving is unlike anything else you will ever learn. It is not a natural skill and it does take some time to master. Although most people will master the skills needed to control the vehicle, there will be some people that will opt for driving an automatic car as opposed to a manual transmission.
What to do in order to start your driving lessons
First, you'll desire your driving licence that is provisionary. No competent trainer must have a student on their initial lesson up till a provisionary licence is seen by them, as it's a vital record you've got to be legal. It is not really difficult to request your provisionary it may take up to 2 weeks to get there be sure to send it to beginning, away nicely ahead.
The theory test
You will likewise need it for your driving theory test, and the useful test so it is a necessary file to have when discovering how to drive. Being prepared and knowing you need a provisional prior to you reserve your driving lessons is essential and without this understanding you will be held back from continuing. In recent years, the theory has got harder to pass as the questions are trickier. The addition of the hazard perception test as also made the test more challenging.
Learning what is important
Identify exactly what is vital. This is one of the most important learning skills to develop. If you are learning to drive a vehicle, getting utilized to the guiding wheel, gas pedal and brake pedal are vital, ideal? All the rest can come later.
Moms and dads will always stress about their kid's safety and up until the youngster reaches an age where they can make their own way home, understanding they have a vehicle and licence to go choose them up is a major merit.
Purchasing car insurance for your kids can be an eye and checking account opening experience. Examine the discount alternatives available to you and you may just discover that you can serious cut down the expenses involved.


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Early signs of bottoming out? 350cc mod plus, 7 weeks post op (photo)
Doctor Answers 8
Early signs of bottoming out? 350cc mod plus, 7 weeks post op
I do see the difference in the 2 sides and the right breast is lower and is at risk for bottoming out. This early after surgery wearing an underwire bra may definitely help prevent the right implant from dropping lower. I would address this with your plastic surgeon.
Web reference: http://www.bostonplasticsurgeryspecialists.com/services/breast-surgery/breast-augmentation/
Early signs of bottoming out? 350cc mod plus, 7 weeks post op
Your implant position looks normal in these photos. Your implants have probably settled over the 7 weeks and as long as they don't drop more, you will have a nice result.
Every doctor has slightly different postoperative protocols. In my experience, many of the differences in protocols between different doctors has a lot to do with how they make the pocket. Most get equal results, so trust your surgeon above any other advice that you get.
Web reference: http://www.nashvillecosmeticsurgery.com/breast-augmentation/
2 months post op, some advices:
Thanks for the question.
In my practice, after performing a BA I recommend to my patients to limit the movement of the arms for two weeks. After that, you can move your arms taking care and always with common sense.
In this regard, it's not advisable to carry heavy weights to prevent the implant out of position, and allow the formation of the physiological capsule around the implant, also to avoid pain and breast swelling.
Kind regards
You might also like...
Am I bottoming out after surgery?
This is early after surgery and I would advise you to check with your local Plastic Surgeon. I might recommend that you consider wearing an underwire bra, realize that a strong position to the implant may have to be considered for the future if this continues to occur after the next several months have passed, and thins can be strengthened with revision if needed.If your implants are textured on the surface, there should be no need for massaging and I doubt there would be further settling or lowering as time moves along.
Good luck to you.
Frank Rieger M.D. Tampa Plastic Surgeon
Web reference: http://riegercosmeticsurgery.comi
Bottoming out?
It does not look like in your photos that you have signs of bottoming out. Follow closely with your surgeon. Best of luck.
Web reference: https://www.stevenwallachmd.com/breast/breast-augmentation/
I agree with you.
While we generally recommend following your surgeon's advice, I will share with you that my own protocol is to indeed wear a bra 24/7 for four weeks after surgery to avoid bottoming out.
If you are concerned I think it would be safe to wear a supportive bra, preferably with an underwire. After discussing with your surgeon, if he or she still recommend otherwise, I would get a second opinion.
Good luck.
Bottom Out?
Your implants appear to be centered under the nipple. This is the ideal position. And its normal for them to become lower in position for the first 12 weeks after surgery. If at 12 weeks, you feel like the implants are sitting too low on your chest, your surgeon can perform a procedure called a capsulorraphy to raise the inframammary fold, if indicated.
Early signs of bottoming out after breast augmentation?
I can understand your concerns and would recommend that you address your concerns with your plastic surgeon again. It may be that after hearing about your concerns, he/she will recommend the use of a more supportive bra and/or additional supportive garment etc. Best wishes.
Web reference: http://www.poustiplasticsurgery.com/Procedures/Procedure_breastAugmentation.htm
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


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Forex: USDJPY downtrend extended to one month low at 90.35
FXstreet.com (Barcelona) - The Yen continued taking ground against the Dollar, and decline from 93.80 high on Jan 7 extended during Asian session as the pair broke below 90.60 support to hit a fresh 4-week low at 90.30 (32.8% Fib retracement of the Nov Jan rally) , before picking up to 90.60 at the moment of writing.
On the downside, below 90.30 session low, the pair might find support at 89.80 (Dec 11 high), and 89.30 (50% Fib retracement of the Nov/Jan rally). On the upside, support levels lie at 90.60/70 and above here, 91.05 (Jan 18 high) and 91.20/35 (Jan 15 high).
EUR/JPY decline from 133.65 resistance area on Jan 14 has found support at 130.00/10 zone, which was tested again on Asian trade. The pair remains consolidating within a range from the mentioned support to 131.00 on the upside. Resistance levels lie at 130.95 and 131.25. Support levels are 130.00 and 129.20.


text: Bigg Boss 5 | Bigg Boss Videos | Sunny | Shakti | Vida | Pooja MishraFilmmaker Mahesh Bhatts darling daughter Pooja Bhatt is enjoying the season of suspense and curiosity over her upcoming movie Jism 2. And all the credit for such unwanted attention goes to Porn star Sunny Leone, whose debut entry in Bollywood has become the recent hottest topic of the nation.After the news that Sunny, during her stay in Bigg Boss 5 has confirmed her debut in Jism 2 has turned out to be a suspense since the recent buzz say that Sunny might walk out of the project due to financial issues. But a smart Pooja Bhatt has decided to keep everyone guessing. I will announce whether Sunny Leone is in the movie or not, but until then, keep guessing, Pooja told Mid Day. I am glad that curiosity has increased so soon. I assure you, we will take this curiosity to the peak. I will not let the heat die down because Jism 2 is going to create a lot more jadoo and lot more nasha, Pooja added.


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Rosie Long Sleeve Blouse
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Get the sheer look with the refined Velvet Rosie Long Sleeve Blouse. A sophisticated statement wardrobe piece, complete with a V-neck, long sleeves and buttoned cuff. Effortlessly style yours with jeans and sandals for a classic look.


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Zooproblematica and mollusca from the Lower Cambrian Meishucun section (Yunnan, China) and taxonomy and systematics of the Cambrian small shelly fossils of China
- First Online:
- Received:
- Cite this article as:
- Parkhaev, P.Y. & Demidenko, Y.E. Paleontol. J. (2010) 44: 883. doi:10.1134/S0031030110080010
- Citations
- 345 Downloads
The monograph presents the results of the study of the Cambrian small shelly fossil fauna of the Meishucun Locality (east of Yunnan Province, China), the reference section for the Cambrian stratigraphy and paleontology of China and the stratotype of the Meishucunian Regional Stage. This publication contains a monographic description of 66 species and 52 genera of zooproblematica and mollusks and an annotated checklist of the small shelly fossil species of the Cambrian of China. The checklist includes 744 nominal species (among them 508 species names are zooproblematica, 220 species names are mollusks, and 16 names represent other groups of organisms). A taxonomic revision of all mollusk and zooproblematic taxa that have ever been described from the Cambrian of China is made at the species and generic levels. We propose that, of the 508 checklisted species of zooproblematica, 221 species should be considered valid, 80 of them are considered as tentatively valid, whereas of the 220 checklisted species of mollusks, 92 species can be considered valid. It was found out that 28 species names of zooproblematica and 7 species names of mollusks should be considered as nomina nuda, since their descriptions do not satisfy the availability criterion. We have to consider 20 species of mollusks and 18 species of zooproblematica as nomina dubia, because these taxa have been described based on unsatisfactory or fragmentary preserved material lacking any diagnostic features. Based on taxonomic work, it has been shown that the great number of synonymous taxa resulted in a more than double overestimation of the real value of the nominal species biodiversity of the Cambrian small shelly fossil fauna of China. The following new taxa are described, i.e. genera: Hexagonellus Demidenko, gen. nov.; Asiapatella Parkhaev et Zhegallo, nom. nov.; Dorispira Parkhaev, gen. nov.; and species: Platyspinites elegans Demidenko, sp. nov.; Mongolodus sulcus Demidenko, sp. nov.; Hexagonellus kuzminae Demidenko, sp. nov.; Halkieria wangi Demidenko, sp. nov.; Asiapatella sinuata Parkhaev, sp. nov.; Pseudoscenella levigata Parkhaev, sp. nov.; Trifistulella tortilis Demidenko, sp. nov.
Based on the analysis of biostratigraphic and chemostratigrahic data, we propose the correlation of the Upper Precambrian-Lower Cambrian boundary deposits of the Siberian Platform and Yangtze Platform. According to this correlation, the base of the Tommotian Stage corresponds to the level within the middle of the Zhongyicun Member of the Zhujiaqing Formation. The monograph contains an extensive bibliography of 379 publications on the subject.


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Should we pay children to read books or to get good grades? Should we allow corporations to pay for the right to pollute the atmosphere? Is it ethical to pay people to test risky new drugs or to donate their organs? What about hiring mercenaries to fight our wars? Auctioning admission to elite universities? Selling citizenship to immigrants willing to pay? In What Money Can't Buy, Michael J. Sandel takes on one of the biggest ethical questions of our time: Is there something wrong with a world in which everything is for sale? If so, how can we prevent market values from reaching into spheres of life where they don't belong? What are the moral limits of markets? In recent decades, market values have crowded out nonmarket norms in almost every aspect of life—medicine, education, government, law, art, sports, even family life and personal relations. Without quite realizing it, Sandel argues, we have drifted from having a market economy to being a market society. Is this where we want to be?
In his New York Times best seller Justice, Sandel showed himself to be a master at illuminating, with clarity and verve, the hard moral questions we confront in our everyday lives. Now, in What Money Can't Buy, he provokes an essential discussion that we, in our marketdriven age, need to have: What is the proper role of markets in a democratic society—and how can we protect the moral and civic goods that markets don't honor and that money can't buy?
©2012 Michael J. Sandel (P)2012 Macmillan Audio
"Book highlights market intrusions in public space"
Sandel articulates the intrusions of market values in public spaces and how that intrusion degrades our coherence as a society and our personal values. His analysis is spot on.
I read nothing that is popular.
"Giving a Buck"
As an Asian descent, my family doesn't buy gifts. Not because we don't believe in purchasing gifts, but we give the gift of cash as our generosity because its convenient and they can buy whatever they want. Although giving money might not be a thoughtful idea to some, but when you give cash or hand them a check, you are not charging some product on a credit card that you have to pay later, and go into debt for something that they will never use.
Giving money might be better for our economy because you need to make sure that you have funds in your account for the check to clear or make sure that you have enough cash to give. The recipient can accept the cash gift and spend it in whatever they want or they can save it for a rainy day. Instead of buying a gift that we cannot afford to give, just give a buck and not be in debt.
When reading this book, start asking yourself what is not for sale and hopefully you will get an ethical stands that money can't buy you everything, but it comes pretty close. Reading what you can actually buy is not surprising because everything is for sale. Paying drug addicts women to not to get pregnant to prevent crack babies, to making your house into a big billboard. Everything is for sale. The most interesting part of this book, is how life insurance got started and how we see death pay out as an investment.
I would never tattoo my body for a free lunch, even it's for a lifetime of free burritos.
Retired Reader
"Mostly common sense"
Interesting but not enough to keep you from setting down the book half way through.
Probably not
Average to middlin'
No way
Not many surprises here. It kind of let me down after hearing the author on TV. I had hoped for a more interesting narrative.
Abu Dhabi, UAE
"I want my Money back on this Waste of Time"
Peter Pan
Not a chance.
He tried to be intellectually honest...but failed.
Page 1 to the end.
This was a painful waste of time.
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Paralysed with silver.
What. A. B*tch.
That girl has some serious issues. I don't own her? Of course I don't bloody own her. And if only she knew what she was saying... "Only my soul" She hasn't got a clue. It would be vaguely endearing if she wasn't so adamant.
Her surface thoughts are so loud, it's like she's shouting them through a microphone at me, but what lies beneath is what I'm after. And she knows it. I pull back, thinking about how I might get into her mind again. The answer clicks. It's so simple. I pull the broken links of silver from my pocket and go behind her. I put my hands on her hips, forcing her to stay still and not turn around. She shouts at me to get off, but I send energy through her figure, paralysing her muscles.
'The bonds of the underworld that you've labelled "hell" have been broken. This mean anything to you?' I send the thought through her and her screaming surface thoughts – dull ordinary things to mask what I want to know – all stop abruptly. Nothing comes to the surface but at least I don't have to hear about some trip she took with a mate a while back anymore.
'No.' She's hiding the truth.
'Liar.' I accuse, putting the silver against her neck. She shivers at the cold touch of the ethereal metal and I bind it to her skin.
'Tell me now?' I ask, walking around to face her again. I pull my glamour back on, the bad boy face, the soft jet black hair, the light dusting of stubble and the defiant look in my eye as my toned six and a bit foot high figure leans in to her. I gently kiss her on the lips and the look in her eyes betrays all. She might not trust me, but I know now what I knew before, the thought only confirmed.
The silver was my channel from before, making whatever pain and suffering that I could feed on as strong and potent as possible. It worked in a similar way now, but at a distance, channelling thoughts and memories instead of pain. Connecting to the silver was not the hard part. Getting the right memory is, though, and I'm being bombarded with useless nonsense. 'Show me your visions' I command through the silver. Gradually they trickle through, the images making only a little more sense than the one I experienced earlier. Frustrated I growl lightly, the cracking glamour distorting. I focus and from the frozen girl's mind, I find all manner of things.
Eventually, I see it. The flashing fire and something about a lock and key to hell. It still makes very little sense, but at least I know I can get what I want from people, regardless of how complex Roxy claims they are.


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4 BR Farmhouse, 65 Acres with Pool, Tennis, Pond, Trails, Guest Cottage(24 Reviews)
The owner has been emailed.
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- Minimum stay:2-7 nights
- Sleeps:12
- Bedrooms:5
- Bathrooms:4
- Property type:Farmhouse
- Internet:Yes
- Pets considered:Yes
- Wheel chair accessible:N/A
About the Property
Farmhouse, 4 Bedrooms (See Description), 4 Baths, (Sleeps 8-10)
The sun filled, roomy farmhouse offers every modern convenience yet retains the charm of yesteryear with stone fireplaces (indoors and out) and a wood burning stove. Traditionally furnished with a combination of antiques and classic pieces, it is comfortable and attractive with plenty of room to gather together yet plenty of room for separate activities and solace.
The fully equipped chef's kitchen, which seats 16-20, offers a professional gas cook top with griddle and warming lamps- perfect for big country breakfasts, double ovens, two dishwashers, a separate beverage refrigerator and an antique farm table- for preparation, or for dining and this room is adjacent to a classic screened in porch- for dining or just relaxing. There is barbeque equipment- gas grill, charcoal grill and smoker off the rear bluestone patio.
After dinner enjoy the outdoor stone fireplace, year round, under the stars or listen to the wildlife from the front porch.
The library/media room has a stone fireplace, flat screen TV with Direct TV service, a VCR, DVD, video games and wireless internet service. This room has a double size pull out sofa. There is a bathroom with shower nearby on this floor.
The sitting room has an upright Steinway piano and is separated from the dining room by a wood burning stove.
There is a guest bedroom on the ground floor with queen bed, double pull out sofa and ensuite bath.
Upstairs, the spacious master bedroom has a queen bed, ensuite bath with heated floor, soaking tub and separate shower.
In addition upstairs, one guest bedroom has a queen bed and another has twin beds. These two bedrooms share a large hallway bath with spa tub and separate shower.
Optional Guest Cottage (only available, at additional cost, with rental of main house) one queen bedroom. Pull out sofa in living room. One bathroom.
Summer/Holiday Rental Rate (will be added to the main house rental rates):
$250/Night Winter, Spring, Fall
$350/Night (Memorial Day, June, July, August, September, Thanksgiving, Christmas & New Year Holidays)
The property is centrally located in the Hudson Valley, 15 minutes to Rhinebeck Village and the Duchess County Fairgrounds for Antique and Craft shows, yet close to the Berkshires; less than 1/2 hour to Catamount for Skiing; or Hudson for antiquing. Convenient to Bard College, Marist, Vassar and the Culinary Institute, as well as local farms for picking apples and berries; the popular fall festivals and convenient to several farm wedding locations. It is just off the Taconic Parkway (less than 1/4 mile) at the Jackson Corners Road exit, 90 minutes from NYC.
You are welcome to e-mail or call with questions.
Keywords: Single Family House
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Member since: 2009
Property Type
- Farmhouse
House Rules
- Children Welcome:
Non Smoking Only:
Comfortable to smoke on screened in porch and outside front porch....moreless
Accommodation Type
- Vacation Rental
- Guests Provide Their Own Meals
Bedrooms: 5 Bedrooms, Sleeps 12, Beds for 8-12
- Other (See Description)
- Bedroom 1: 1 queen
- Bedroom 2: 1 queen
- Bedroom 3: 2 twin/ single
- Bedroom 4: 1 queen, 1 sleep sofa /futon
Bedroom 5- in cottage: 1 queen
This bedroom is located in a separate cottage at addtl cost...moreless
- Queen size Beds (3), Twin or Single Beds (2), Sleep Sofa or Futons (3) 2 Double size; 1 Twin. Additional Queen bed in cottage. (additional cost)...moreless
Bathrooms: 4 Bathrooms
Other Amenities
- Books
- DVD Player
- Games
Music Library:
Ipod hook up into reciever so you can use your ipod. Internet radio....moreless
- Satellite / Cable:
- Stereo
- Television:
- Toys
- Away From It All
- Family
- Historic
- Romantic
- Sports & Activities
- Tourist Attractions
- Churches
- Cinemas
- Festivals
- Health/Beauty Spa
- Live Theater
- Marina
- Museums
- Playground
- Restaurants
- Winery Tours
Local Services & Businesses
- ATM/Bank
- Fitness Center
- Groceries
- Hospital
Leisure Activities
- Antiquing
- Bird Watching
- Boating
- Horseback Riding
- Horseshoes
- Scenic Drives
- Shopping
- Sight Seeing
- Sledding
- Wildlife Viewing
Location Type
Sports & Adventure Activities
- Basketball Court
- Cross Country Skiing
- Cycling
- Equestrian Events
- Fishing
- Fly Fishing
- Freshwater Fishing
- Golf
- Hiking
- Hot Air Ballooning
- Hunting
- Kayaking
- Mountain Biking
- Rafting
- Rock Climbing
- Sailing
- Skiing
- Snowboarding
- Snowmobiling
- Swimming
- Tennis
in addition to dining room, kitchen also features farm table for 8 and round table that expands to seat 12...moreless
- Dining Room
- Seating for 10 people
- Air Conditioning:
- Broadband Access
- Clothes Dryer:
- Computer Available:
- Fireplace:
- Free Long Distance:
- Hair Dryer
- Heating:
- Internet:
- Iron & Board
- Linens Provided:
- Living Room
- Parking
- Parking Off Street
- Coffee Maker
- Cooking Utensils:
- Dishes & Utensils:
- Dishwasher:
- Ice Maker
Professional 4 burner gas cooktop with griddle, potfiller and heat lamps. Two sinks with two dishwashers. Double oven. Microwave. Separate beverage refrigerator...moreless
- Microwave
- Oven:
- Boat:
Deck / Patio:
Rear and side patios, one with outdoor stone fireplace. Large screened in porch, adjacent to kitchen for additional dining....moreless
RatesCurrency Conversion
|Weekend Night
|Monthly *
memorial day weekend
May 25 - May 30, 2017
3 night min stay
Jun 1 - Jun 29, 2017
3 night min stay
July 4th weekend
Jun 30 - Jul 5, 2017
3 night min stay
Jul 6 - Jul 31, 2017
7 night min stay
Aug 1 - Aug 31, 2017
7 night min stay
Sep 4 - Oct 1, 2017
3 night min stay
Oct 2 - Oct 31, 2017
2 night min stay
My Standard Rate
2 night min stay
Additional information about rental rates
- exit cleaning $180
- Taxes Not included
*Guest Cottage available as additional space (only available with the main house) $200 per night, $1000 per week 3,000 per month.
*Exit cleaning fee $150 main house- $75 cottage
*Only small well trained dogs considered
Owner's cancellation policy:
Policy available by contacting owner when booking
Don't forget your vacation protection! Get protected now
Adding our Vacation Protection services can make sure your getaway goes smoothly, no matter what. We offer Cancellation Protection and Damage Protection so you can truly relax.
Car: Necessary
Close to Rhinebeck, Red Hook, Pine Plains, Millerton, Tivoli, Bard College, Marist, Culinary Institute, Vassar, TriArts theater, Hudson antiques, Duchess County Fairgrounds. Dinsmore golf, Catamount for skiing; farms for picking fruit and vegetables, fall festivals, Hudson River historic estates (Clermont, FDR, Vanderbilt) and many area wedding reception sites.
Owner info
Contact us
Send email
- Primary: (917) 848-9187 (New York, USA)
Links to more information:
- Click Here to see All My Rental Listings
Kitchen view from screened porch
Front of house
Pond and Gazebo
Pool, (fenced)
kitchen looking onto screened proch
Dining Room
Living/Sitting Room view from dining room. Sofa (twin converts to single bed.
Master Bath
Upstairs Guest-Twins, shares large hallway bath.
From under a tent, set for reception
Large Outdoor Stone Fireplace on side patio; we use this in January and July!
Pond site, set for wedding
Under gazebo
Tennis and Basketball
screened porch, off kitchen
Library/Media Room with access to side patio. Sofa converts to double bed
Master Bedroom, upstairs, with ensuite bath.
Upstairs Guest Room-Queen, shares large hallway bath.
Main Floor Guest room; Queen bed with bath and sofa that converts to double bed.
Wedding reception evening view
Evening reception
View from front of house
This listing was first published here in 2009.
Date last modified - Tuesday, May 23, 2017
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All Items : Antiques : Furnishings : Furniture : Continental : Neo-Classical : Pre 1837 VR item #1179797 (stock #8734)
Neo-Classical ormolu mounted dressing table in mahogany having a rectangular top with two incurved small drawers and an elevating cheval mirror above a frieze drawer and two cabriole legs ending in hoof form feet on an incurved platform base. Probably Baltic, circa 1830-1840.
Height: 38" (closed)
Height: 38" (closed)
Height: 59.75" (open)
Width: 37.25"
Depth: 16.25"
All Items : Antiques : Furnishings : Furniture : Continental : Neo-Classical : Pre 1900 item #1097928 (stock #6896)
Unusual Antique Green Marble Pedestal, in the form of two columns with a rectangular stepped plinth base and a rotating top for viewing sculpture. The form is reminiscent of Grand Tour memorabilia.
Height: 43.75"
Height: 43.75"
Base: 8.75" x 15.25"
Top: 8" x 14.75"
**plese note: because of the weight, the pedestal is currently in four pieces. It will need to be assembled and glued together for stability


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A proposal to resurrect a gas station at the corner of Vliet and 60th streets drew strong objection from 10 neighborhood residents at Monday's Plan Commission meeting.
"I am definitely asking you to not approve this type of incursion of additional traffic and congestion where it is neither needed nor wanted," Marilyn Mayr said.
Mayr got her wish, at least temporarily.
The commission sent the proposal back to staff for more work, and asked the developer for more detailed plans.
Mayr, like other opponents of the proposal, is a resident of Lombard Court, a short, 10-home cul-de-sac that curls from Vliet Street to a point behind the station. An alley separates the gas station and neighboring business to the west from some of the homes and yards of Lombard Court.
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Eiff said traffic is sometimes "dense" around that corner, and she said she was concerned that gas station customers would add traffic to the court and alley.
The gas station began operating in the mid-1960s, said architect Robert Wold, who appeared on behalf of the applicant, Mandeep Dhawan. Although it has a large canopy and pumps, the station has not sold gas in some time. The current proposal is to add a second canopy and more pumps, and open a convenience store in the building, Wold said.
"I'm not here strictly to speak in opposition," said Alderman Dennis McBride, who appeared on behalf of residents, "but to ask the Plan Commission to take into consideration some of the concerns that the neighbors have just raised."
While many residents who spoke objected to the convenience store element of the plan, pointing to other convenience stores in the immediate neighborhood, McBride said he did not oppose a convenience store in principle.
"I don't think you as a Plan Commission or we as a Common Council are in the business of picking winners and losers," he said. "However, I do think that the traffic concerns are real here, especially for people on Lombard Court."
The Meritage Restaurant, Times Cinema, Highlands Café, Café Perrin, Grandma's House Daycare, Promolux promotional apparel, Sazama remodeling and a beauty parlor are all within a block of the gas station site, and, residents said, contribute to traffic at various times of the day.
"It's a rising community," Commissioner Jody Lowe said.
The commission's unanimous resolution asked the applicant to return within 90 days with plans that show an improved appearance of the business, answer questions about the size of a second canopy, address gas delivery routes and answer other questions. The commission asked city staff for a traffic study of the blocks that would be affected.
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- Wauwatosa News and Notes: Hands-only CPR training offered; Firefly Art Fair is Aug. 6-7
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Worldwide sea piracy has fallen to its lowest levels in four years, according to the International Maritime Bureau, with attacks off the coast of Somalia falling sharply.
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Billions of dollars of goods and up to four per cent of the world's oil supply pass through the Gulf of Aden between Yemen and Somalia.
Somalia has not had an effective coastguard during much of its 20-year civil war that followed the collapse of its central government in 1991.
- More about:
- Africa
- Anonymity
- China
- East Africa
- Gangster And Gangs
- Nairobi
- Navy
- Security
- Somalia


text:
Mr Byatt also warned that while companies have spent pounds 15bn on capital investment over the last five years, spending is now in a trough. "I am concerned les companies may lose their momentum ... the drought has shown the need to provide a more reliable service; this should be done without any increase in prices," he said.
The statement increases the pressure on the industry, which has been widely attacked for failing to invest enough in measures to stop leakage from the water pipes - in some cases as much as 25 per cent.
Mr Byatt's comments come in Ofwat's latest report on the financial performance and investment in the sector. It shows that over the five years to 1994/95, the sector borrowed pounds 3.5bn but that, at present, they are generating enough cash to meet investment needs.
Mr Byatt said that the new price controls which came into effect in April aim to ensure that future profits grow at a "modest rate". Since privatisation, profits have increased by almost 41 per cent in real terms.
- More about:
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- Plumbing
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Mixed Tomatoes And Arugula Salad With Crispy Polenta
- Servings: 6
- 2 cups mixed tomatoes, such as red and yellow cherry, grape, and teardrop, roughly chopped
- Coarse salt
- 12 to 15 large fresh green basil leaves
- 2 cups fresh purple basil leaves
- 1 small red chile, halved, stemmed, seeded, and thinly sliced crosswise
- 3 cups baby arugula, washed and dried
- 3 cups fresh pea shoots
- 1/4 cup extra-virgin olive oil
- 1 tablespoon balsamic vinegar, plus more for drizzling (optional)
- 3 cups Crispy Polenta
- Parmesan cheese, shaved, for serving
Place tomatoes in a large bowl; season with salt. Add green and purple basil; toss to combine.
Add chile, arugula, and pea shoots.
Drizzle with olive oil and vinegar; toss to combine.
Toss in polenta.
Transfer to a large serving platter; top with cheese, and drizzle with more vinegar, if desired. Serve immediately.


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- EarthChoice Colors Opaque Text & Cover
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TICKER SYMBOL (NYSE: UFS) (TSX: UFS) MONTREAL, Dec. 3, 2013 /PRNewswire/ - Domtar Corporation (NYSE: UFS) (TSX: UFS) today announced the fifth update to its award-winning site, The Paper Trail ( www.domtarpapertrail.com) since the debut of this groundbreaking tool in June 2011. Publicly showcasing the company's commitment to voluntary disclosure, The Paper Trail provides a look at the social and economic impacts associated with manufacturing its paper products in North America. As a tool that displays both what Domtar is doing well at its facilities, as well as what it's working to improve upon, the Paper Trail continues to serve as a model for transparency within the industry. The tool will now include even more papers from the environmentally and socially responsible EarthChoice ® product line:


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Spring / Summer
For true western Canadian hospitality, there is no better place to stay than the Hilton Garden Inn West Edmonton. There are 160 newly renovated and beautifully appointed guestrooms and the hotel offers a wide range of services and amenities designed for comfort and convenience. Hilton Garden Inn's friendly and helpful staff will make sure your stay in Edmonton is unforgettable.
Nearby Attractions
Staying in this West End hotel allows you easy access to these great Edmonton attractions:


text:
Taran C.
Nanny in Oak Lawn, IL 60453.
Looking for full or part-time work as a nanny.
Enhanced Background Check not run.
Enhanced Background Check(Not Run)
Basic Background Check Expired
Basic Background Check Expired 12/16/2013
Motor Vehicle Records Check not run.
Motor Vehicle Records Check(Not Run)
First Aid Training
First Aid Training
CPR Training
CPR Training
Oak Lawn, IL
- Age 31
- 10 years paid experience
- Female
Last signed in: This week
Rating (2 reviews)
Taran is the absolute best sitter I have ever had. My 4 year old and one year old love her. I have used her abou...
Preferred Rate $15-$22 per hour
Taran's Bio
I think children need to have fun, respect adults and be free to make mistakes while exploring the world. I believe in kissing boo-boos and time out chairs. I believe that a spoonful of sugar helps the medicine go down and "please and thank you" should be used liberally. I don't hesitate to say no when necessary but I take pride in the fact that I'm a fun-loving nanny who usually says yes. I think that children should be heard and their opinions valued but that "Mom knows best" and actions have consequences. I believe that communication between nanny and parent is the key to a great working environment. I'm always open to exploring alternative parenting styles and can adapt to any family's needs.
During my time as a nanny I have done the following: potty trained toddlers, successfully used and reinforced the teachings of "1-2-3 Magic" by Thomas Phelan and "Happy Sleep Habit, Happy Child" by Marc Weissbluth. I have administered medication including inhalers and nebulizers. I have dealt with colicky babies, children with food allergies and I have some knowledge on nutrition. I also have some experience with cloth diapers. Additionally, I am up to date on my flu and Tdap vaccine.
I love kids and I have a lot of experience with newborns to teenagers. I am the second oldest of six; I have 4 brothers and 1 sister. I am very familiar with Chicago and its surrounding areas so I would love to take the kids on adventures to museums and zoos. I would also enjoy just taking kids to the park or a nearby library. I love to read stories, play games, do crafts, bake and sing songs with the kids. I am Infant/Child CPR trained and I have great references.
Age Specific Experience
10 years of paid child care experience with:
- First year
- Toddlers (1 to 3 years)
- Preschooler (3 to 5 years)
- Grade School (6 to 11 years)
- Pre-teen/Teenagers (12 years and over)
6 to 10 years of infant care experience
Infant Care:
- Instruction (proper swaddling, feeding, changing, bathing)
- Assist with setting a routine
- Overnight care
- Mother's helper
- Occasional care
Availability & Job Preferences
Availability Duration
Has a child who needs to accompany care provider on the job
- Short-term (1 to 3 months)
- Temporary (4 to 12 months)
Job Duration
- Will consider either a part time or full time position
- Start date is flexible
My availability is valid through 11/10/16
- Open availability on weekdays (M-F)
Skills & Abilities
Homework Help:
- Finishing homework
- Checking answers
- Studying for a test
- Proofreading
- Basic Math
- Pre-Algebra
- Elementary Science
- Essay Writing
Additional Services:
- Meal Preparation
- Laundry
- Light Housekeeping
- Swimming Supervision
- Crafts
- Potty Training
- Travel with Family
- Willing to run errands as needed
- Willing to drive children to events, school, appointments, or carpooling
Taran was absolutely fabulous. Both my husband and I were extremely comfortable leaving her with our children. We'll definitely be calling her again!
Taran is the absolute best sitter I have ever had. My 4 year old and one year old love her. I have used her about 6 times and everytime she has a new activity for my daughter to do. FANTASTIC! She understands what it takes to keep a house running while mom and dad are gone and does not hesitate to jump right in. I feel so comfortable leaving her in charge!
|Alicia S. is a reference for Taran C.
|Relationship: Former Employer
|Join Now to Contact Reference
|Katie D. is a reference for Taran C.
|Relationship: Former Employer
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text:
Academic Policies
Governing Policies for Satisfying Academic Requirements
Policies which apply to all Degree Completion Programs (DCP) are set forth in this section. Additional requirements applicable to specific DCP programs are stated in the curricular outlines that appear in the academic programs requirements section of the catalog. DCP observes the general academic policies of the university, except as indicated below.
The ultimate responsibility for understanding university policies and meeting all degree requirements rests with the student.
Students Subject to the Catalog Provisions
All students are subject to the provisions of the catalog which was in effect at the time of their first enrollment at John Brown University, with the exception of charges for tuition, etc., which apply only for a specified period of time. If a student leaves JBU and later returns, that student is subject to the catalog in effect at the time of re-enrollment.
Changes in Requirements and Regulations
The university reserves the right to make modifications in policies, procedures, and regulations: e.g., grading system, transfer of credit, guidelines for degree requirements, housing regulations and charges, tuition and fees, and admission standards, and to make such modifications applicable to any or all currently-enrolled students. When modifications occur, sensitivity to reasonable dates of implementation and appropriate categories of currently-enrolled students affected will be exercised. Students will be notified of such changes through their Advisor, written notices, and campus publications.
Course Credits
The basic unit of course credit is the semester hour.
Prerequisites and Corequisites
Students are not permitted to enroll in courses for which they have not completed all prerequisites. A prerequisite course must have been completed with an acceptable passing grade before enrollment in the given course is permitted. A corequisite is a course in which a student must be enrolled and satisfactorily participating simultaneously to the given course.
Transfer of Credit
Credit which has been earned at another institution will be reviewed by both the Registrar and the Department Head, and the applicability to courses in the chosen degree program will be determined. Each course accepted for transfer must have a minimum grade of 'C'. All work completed at previous institutions will be posted as 'CR' on the student's JBU transcript. Thus, only JBU course work will apply toward the student's grade point average. Credits from institutions which are not regionally accredited may be accepted on a case-by-case basis.
Currently enrolled students planning to take course work at other institutions must receive prior written approval of their Advisor and the Registrar. Official course descriptions of proposed work may be required.
Transfer of Credit into the Major
Some students may previously have completed courses which are deemed equivalent to certain JBU courses. Applicability of credit is determined by the Registrar's Office, who may establish a maximum number of outside credits to be transferred, depending upon the type of curriculum and the awarding institution.
Credit Options
The credit applying toward a degree may include as many as 62 semester hours earned by means of alternative activities, such as credit by exam (30 hours maximum) and credit for prior learning (16 hours maximum) or credit for military training. In addition to taking elective courses, there are several non-traditional credit options available for students to earn credit toward a JBU Degree Completion Program degree, including:
Credit by Examination
Students may earn credit through selected nationally recognized standardized tests. Such tests include the College Level Examination Program (CLEP), the DANTES Subject Standardized Tests (DSST) and certain other tests approved by the American Council on Education (ACE). A maximum of 30 credit hours may be earned by examination.
Credit for Prior Learning (CPL)
The university recognizes that collegiate-level learning may occur outside the college/university classroom and has established specific procedures and policies for evaluating and granting credits for such learning. CPL may be earned only for documented and currently held learning, and is not granted simply for experience. This learning may have resulted from personal study, travel, work experience, workshops and seminars, military training, or other professional or vocational experiences. The guidelines recommended by the Council for Adult and Experiential Learning will generally be followed, except where they might conflict with existing policies of the university.
Some classroom-based corporate or military learning experiences have been evaluated for college credit equivalency by the American Council on Education, Program on Non-collegiate Sponsored Instruction (PONSI), or other nationally recognized organizations. In these cases, official transcripts or other direct documentation must be provided.
To request credit for other types of prior learning, students are required to complete a Petition for Academic Credit and prepare a portfolio which documents the learning. Such a portfolio typically involves one or more of the following:
a. Submission of a Technical and Professional Training (TPT) worksheet which demonstrates learning attained through workshops or other training experiences that have not been evaluated by ACE, PONSI, or other nationally recognized evaluation organizations.
b. A life-learning essay, at least eight pages in length, developed according to the Kolb model and based on experiential learning which may or may not have resulted from formal instruction and is determined to be consistent with the John Brown University curriculum.
In the life-learning essay, the student is to demonstrate how the outcomes of the experiential learning are similar to those of a particular course, or are appropriate to be considered as a topic within a particular subject area. Completed materials are submitted to the Associate Registrar for Degree Completion who then forwards them to a faculty evaluator in the appropriate discipline.
Evaluation of TPT worksheets and life-learning essays is done by the faculty of the university. Faculty evaluators may request additional documentation or restructuring of the student's petition before awarding credit.
CPL based on faculty evaluation (TPTs or life-learning essays) is limited to 16 semester hours total per student. The posting of CPL on a student transcript will be in a category labeled as such. If credit is awarded, a designated course number will be used across the curriculum, with the distinct prefix of a department to indicate the area of learning. The course title will be chosen by the faculty evaluator and the student.
Students will be charged a fee for the portfolio evaluation. Payment of the fee in no way guarantees that credit will be awarded.
Visit with your admissions counselor about non-traditional credit options, or review our class schedules for online and face-to-face elective options at http://www.jbu.edu/dcp/admissions/credit_options/.
Maximum Experiential Credits
The maximum total credit allowed for vocal and instrumental ensembles toward the requirements of a bachelor's degree is four hours.
Traditional Courses Taken at JBU
Students who enroll in any JBU classes that are not part of the Degree Completion Program will be subject to the policies of the traditional university program (parking privileges, drop/add schedules, registration deadlines, fees, etc.) as appropriate. These policies are found in the JBU online catalog.
Enrollment Status
Degree Completion students are considered full-time if they enroll in twelve hours per term.
Students enrolled in the online degree completion majors are full-time if enrolled in a total of twelve hours per 16-week semester (online semesters are comprised of two eight-week terms).
Maximum Course Load
To be considered a full time student, Degree Completion Online students must complete 12 hours during a reporting term. However, students are allowed to complete up to 18 hours during one reporting term (nine hours in Term 1 classes and nine hours in Term 2 classes). Students who have been placed on academic probation will be limited to 15 hours during one reporting term.
Late Enrollment
Any student who enrolls after the close of the regular registration period may be subject to limitations in the course load and a late registration fee.
Attendance Requirements
Because of the intensive nature of the curriculum and the participatory structure of course work in these programs, it is imperative that students attend every scheduled class and participate in each week's activity for courses delivered online.
Hybrid Delivered Programs
Hybrid courses require online and face-to-face activities weekly. In the hybrid programs, missing three sessions, excused or unexcused, will result in a grade of 'F' (face-to-face or online).
For face-to-face classes, students who fail to attend any 15 minute consecutive period of a class session may be considered partially absent. Two partial absences for any one course are the equivalent of one absence of the respective course.
For the online classes, students are expected to login to the Blackboard module regularly (at least 3 days a week) to check the announcements and work schedule, and complete all assignments for the week. (The due date for assignments may not be extended for purposes of achieving attendance.)
An "absence" for online class is defined in two ways (either of which will incur an absence):
1. not submitting any assigned work for the week;
2. not demonstrating evidence of reading assigned chapters or viewing assigned videos, tutorials, or other media posted by the professor.
Evidence includes posting to discussion forums, responding to other students' posts, and generally logging in to participate and engage in course materials.
Excused absences are defined as an absence that are unforeseen, emergency or life threatening (required documentation).
1. Death or serious illness in the immediate family.
2. Local emergencies requiring immediate attention (examples: tornado damage, flooding, etc.).
*Students are responsible for providing written evidence by email with any supporting documentation attached to substantiate "excused absences."
Unexcused Absences are defined as an absence that are cannot be documented or for personal reasons.
1. Non-emergency medical/work/personal reasons, which cannot be documented.
*Instructors are neither obligated, nor expected to permit a student to make up work missed because of unexcused absences. If a student is allowed to make up such work, full credit may not be allowed.
It is the responsibility of the student to notify the professor in advance of any activity that will interfere with class attendance. Such notification must be made in a manner consistent with the stated expectations in the professor's course syllabus (using JBU email).
Late Assignments
Students are required to submit all assignments when due. Homework is designed to prepare students for class collaboration and learning. On a case-by-case basis, instructors may accept late work for partial credit at their own discretion. If late work is accepted it is subject to a 10% reduction per day late. Unless there is an extreme emergency or medical event (documentation is required), assignments will not be accepted for credit, if it is not submitted within seven days of the original due date.
Orientation to Online Learning
This eight week course serves to create an understanding of Christian higher education and orientation experience for incoming students preparing them for success in the program. A passing grade and completion is a mandatory requirement to continue in any DC program. Attendance is critical to overall success in the program.
Textbooks and Other Course Materials
Students have options for obtaining most books and materials for their courses. As part of the preregistration process, students are given the option to receive materials from the bookstore at JBU, which is operated by Follett Corporation, by purchasing new, used, or renting. Students may also choose to purchase materials from other sources, but are responsible to make sure they have the correct edition of texts. Students with adequate financial aid may be able to obtain their materials from the bookstore using that aid.
Inclement Weather Policy
During the winter season, inclement weather sometimes necessitates the cancellation of face-to-face classes. Rather than calling your Center, please take advantage of JBU's communication options.
There are a few ways to know if your class is canceled. The easiest is to register for Information Alerts via the Crisis Alert System on JBU's intranet, EagleNet. The CAS is location specific and is the most up-to-date information available about class cancellation. (Note: class cancellations are an information alert – not a crisis alert – so make sure to register for Information Alerts to hear when classes are cancelled.) Alerts are sent to your JBU email and via a phone call. You may also choose to receive information via text messaging or to an alternative email address. In most circumstances, the decision to cancel is made around 3:00 p.m. Keep in mind, if there is no notification, it's safe to assume that your class will meet.
In addition, we will post closing information on each Center's Facebook page (click the link for each location's page).
- Fort Smith
- Little Rock
- Rogers
The information will also be posted to the JBU Degree Completion website, on the program's Twitter page and broadcast on local television and radio stations when possible.
Note: only face-to-face classes are cancelled due to inclement weather; online classes will continue as scheduled, regardless of weather.
Due to the accelerated nature of our curriculum, all face-to-face Degree Completion courses will require a makeup course session. If your class is cancelled, you can expect to hear from your office manager and/or instructor regarding meeting times for a makeup session.
Your safety is our utmost concern, so if classes are being held but road conditions make it too dangerous for you to attend, please contact your instructor as soon as possible to determine how to submit your missed assignment(s). Again, we ask that rather than calling your Center, you plan ahead by choosing one of the above options to access any inclement weather notifications.
Classroom Demeanor
Students are expected to display classroom and online behavior that is appropriate to a Christian university. A professor may remove a student from a class if, in the professor's judgment, the student displays behavior that is uncivil, defiant, or otherwise disruptive to the classroom learning environment. Students dismissed from a class may not return to the class without the permission of the professor. Online postings require polite behavior; evidenced in font, word use, and grammar that is indicative of college level communication.
Academic Integrity
As a Christian institution of higher education, John Brown University seeks to maintain the highest standards of academic integrity. Violations of these standards will result in substantial penalties. Violations and their definitions are as follows:
a) Plagiarism: Submitting as part or all of one's own work material that is copied or paraphrased from another source, including online sources, without the proper acknowledgment of that source. Examples include: failing to cite a reference, failing to use quotation marks where appropriate, misrepresenting another's work as your own, etc.
b) Cheating: Using unauthorized material or study aids for assistance on examinations or other academic work. Examples include: looking at a peer's exam, altering a graded exam, using notes without permission, etc.
c) Fabrication: Submitting altered or contrived information in any academic assignment. Examples include: falsifying data, text material, or sources.
d) Facilitating academic dishonesty: Helping another student violate this policy. Examples include: allowing one's work to be copied, working together on an assignment where collaboration is not allowed, doing work for another student.
Faculty Action Regarding Violations of Academic Integrity
All violations of the academic integrity policy will be reported to the Dean, who will maintain a file on student offenses.
First offense: In the first case of dishonesty, the faculty member will normally give the student a zero for the assignment or test on which the student has been dishonest. Faculty members are free to impose more severe penalties if such penalties are announced in the course syllabus.
Second offense: A second violation of the integrity policy in the same course or in any other course will result in an F in the course.
Third offense: Any further violations of the integrity policy may result in suspension or dismissal from the university.
A student who feels that he or she has been unfairly accused or unjustly treated may appeal to the Dean.
Grading System
Indication of each student's progress is reported regularly by instructors. Grades are issued following each term. The grading scale used as a basis for letter grades is established by the instructor of each course. Grade points per semester hour (effective Fall 1999) are determined as follows:
|Superior Accomplishment
|Commendable Accomplishment
|Satisfactory Accomplishment
|Minimal Accomplishment
The following are not included in grade point average:
|I - Incomplete Work
|S - Satisfactory
|NC - No Credit Earned
|U - Unsatisfactory
|WP - Withdrew Passing
|WF - Withdrew, Failing
|W - Withdrew
|Earned Grade
Incomplete Grades
In extenuating circumstances, students may be allowed to receive an incomplete ('I') grade for a particular course only with prior approval of the instructor. The remaining work must be completed according to arrangements made with the instructor but no later than one month after the original due date. If the student does not complete the work by this deadline, the instructor will assign a grade based on work received, or the grade will convert to 'F' automatically by the Registrar.
Dropping Courses
If a student wishes to drop a course during a term, the student must notify their Advisor before the first class session. The Student Accounts Representative will credit the student's account for that course's tuition. The course will not appear on the transcript.
If the student withdraws after the beginning of the first class but prior to the third meeting, the student will receive a 'W' for the course. After this time, the student will not be eligible for a grade of 'W'; the student will receive the grade earned. Withdrawal from the university or dropping a course may have implications for student financial aid or veterans' benefits.
Tuition will be refunded to the student and a grade of 'W' or 'F' will be posted based on the following schedule:
Drop Notification/Refunds
Drop Notification/Refunds for Degree Completion OM Cohort Courses
Amount of Refund
Grade Earned
Prior to the date of the 1st session of a course
100% refund
No Grade
On or after the date of the 1st session and before the date of the 2nd session
75% refund
On or after the date of the 2nd session and before the date of the 3rd session
50% refund
On or after the date of the 3rd session date
No refund
Earned Grade
Drop Notification/Refunds for Degree Completion Courses (excluding OM Cohort Courses)
Amount of Refund
Grade Earned
During the first week of classes
100% refund
No Grade
During the second week of classes
80% refund
During the third week of classes
40% refund
After the third week of classes
No refund
Earned Grade
Students taking hybrid courses can only change from hybrid to online or vice versa during week 1. After week 1, changes in modality cannot be made. Please contact your advisor for more information.
Other non-tuition fees are not refundable. See refund policies for Traditional Undergraduate Studies and Graduate Studies if enrolling in courses from those programs.
Re-Enrolling in Courses
If a student drops, withdraws, or fails a course, the student will need to contact their Advisor to determine when the course is offered again and how to re-enroll in the course. The cost for repeated courses (those for which the student received a 'W' or 'F') is full tuition.
Auditing Courses
Degree Completion students may register for courses on a non-credit or audit basis provided the proper procedure is followed, either at initial registration for the term or by official change of registration prior to the stated deadlines. The names of such students will be entered on the class roll, and the class appears in the student's academic record, but without credit and with final grade of 'S' or 'U'. It is the responsibility of the student to obtain a statement of grading criteria for satisfactory participation from the instructor. Tuition is charged at one half of the rate of for-credit registration and subject to the same regulations.
Grade Renewal
A student may repeat any course on his or her academic record with prior approval of the Department Head and the Registrar, with the understanding that all courses and grades will remain on the permanent record. However, only one taking of the course may contribute hours to the total for graduation, and only the highest grade received will be included in the calculation of the student's grade point average. If the student receives permission and renews a grade by means of transferring an equivalent course from another institution, the completed course is posted with a grade of 'CR', and any prior attempts are excluded from graduation hours and the grade point average.
Grade Point Average
To receive a degree the grade point average of all degree work must be at least 2.0, and in the major at least 2.25.
Residence Requirements
Fulfillment of the residence requirements for a Degree Completion bachelor's degree from John Brown University consists of completion by means of courses taken in residence of at least 36 hours of credit presented in fulfillment of degree requirements. Of those, at least 32 hours must be in the major field of study.
Scholastic Probation & Required Achievement for Continued Enrollment
- A student with a cumulative grade point average (CGPA) less than 2.0 will be placed on probation the following term.
- The maximum enrollment per term for any student on scholastic probation is 15 term hours. Students should understand that such limited enrollment may lengthen the time required to meet graduation requirements.
- A student whose CGPA is still below 2.0 after being on probation for two successive terms, or a student with less than a 1.0 term GPA, will be suspended unless a petition for re-enrollment is approved by the Associate Registrar.
- A student may enroll after one term of academic suspension if a petition is approved by the Associate Registrar.
- A student who is permitted to re-enroll after academic suspension may continue to re-enroll if satisfactory progress is being made toward a 2.0 CGPA as determined by the Registrar's Office.
- A student on scholastic probation may remain eligible for some types of financial aid, if standards for Satisfactory Academic Progress are met.
Minimum Total Semester Hours
Completion of any bachelor's degree at John Brown University requires at least 124 hours of academic credit. Certain programs exceed the minimum.
Sufficient courses must be completed to offset any deficiency in total number of semester hours in addition to all other specific requirements, preferably in an area which will enrich and broaden the student's acquaintance with the major areas of knowledge.
Non-Degree Seeking Students
In most cases, a maximum of 15 hours may be completed under non-degree status. Permission to take more than 15 hours is subject to approval by the respective Program Director and the Dean. Students enrolled in degree programs have priority over non-degree students in class registrations and on waitlists. Non Degree seeking students must meet the admissions requirements required for the Degree Completion program in order to register.
Double Major
Students who wish to pursue a second major within the Degree Completion Program must complete all unique hours within the second major. Students are allowed to transfer in up to 25% of the second major from another university. Students who wish to complete a second major must do so prior to graduating. Once a student has graduated they cannot add a second major.
Additional Bachelor's Degrees
For two bachelor's degrees, a minimum of 154 semester hours must be completed incorporating all requirements for both degrees. A maximum of 36 credits by exam may be included. All other stipulations of the residence requirements apply to the second as well as to the first degree.
Fresh Start Policy
A student who re-enrolls in the university after an absence of seven or more years and completes one full-time semester or term with a 2.0 GPA or higher may request a "Fresh Start" by petitioning the Dean. If the petition is approved, none of the credits earned prior to the absence will be included in the GPA calculation and only those with a 'C' or higher may be used to fulfill graduation requirements. In effect, the Fresh Start treats early JBU work as transfer work. After the "Fresh Start" is applied to a student's transcript, those courses with a 'C' or higher will be designated by 'CR' and those with a 'C-' or lower will be designated by 'NC'.
Application for Graduation
An Application for Graduation form, available on-line during the preregistration process, should be completed when registering for the final semester or term in residence before completion of degree requirements. This application provides information regarding the graduation fee, exit assessment requirements, and a final check of the student's name as it is to appear on the diploma and in the commencement program. A graduation application fee will be charged to the student's account at the time the application for graduation has been submitted.
Participation in Commencement Exercises
Degree candidates may participate in commencement exercises only upon completion of all degree requirements no later than the last day of the semester. Any course work in progress at other institutions must be completed during terms ending no later than one week following JBU commencement.
Students not enrolled at JBU during the semester in which they plan to graduate must contact the Registrar's Office in writing during the first two weeks of the term, declaring their intention to participate in commencement. Failure to do so may result in the student not being listed in the printed commencement program.
Eligibility to participate in commencement is limited to the commencement at the end of the student's final semester in attendance or the commencement at the end of the following semester. Furthermore, participation eligibility is dependent upon compliance with all of the deadlines posted on the commencement web site.
Scholastic Awards
Recognition of Superior Achievement
Full-time students attaining certain standards of scholastic achievement are placed on the President's or Dean's List of Distinguished Students at the end of each term. To qualify for the Dean's list, the student must have at least 3.4 term GPA on a minimum of 12 semester hours, and at least 3.8 term GPA for the President's list.
Degree Honors
Upon completion of the bachelor's degree, each graduate who has attained a cumulative grade point average of 3.6 or above is recognized with an appropriate degree honor. Eligibility is contingent upon completion of at least 60 semester hours of graded course work at John Brown University. Graduation honors are indicated on the diploma and by the wearing of an appropriate medal on the gown during the commencement exercises.
Cum Laude-Grade point average at least 3.6
Magna Cum Laude-Grade point average at least 3.8
Summa Cum Laude-Grade point average at least 3.9
Students who have between 39 and 59 semester hours of graded course work at John Brown University and have a grade point average of 3.8 or higher will graduate "with distinction." With Distinction honors are indicated on the diploma and by wearing of an appropriate tassel on the cap during the commencement exercises.
An official transcript of a student's academic record may be obtained by submitting a transcript request form to the Registrar's Office, provided the student has made satisfactory arrangements with Student Account Services with respect to financial obligations. Transcripts are not released unless the student grants permission through a signed statement.
The first official transcript is issued without charge; a $5 fee is incurred for each official transcript thereafter.
Official transcripts of academic credits are not released while the student's account is in arrears. The university engages professional collection agencies to deal with delinquent accounts, as necessary.
Withdrawal from the Program
Students wishing to withdraw from a Degree Completion Program must contact their Advisor.
Academic Grievance Process
To file a complaint about a faculty person—the way they conducts class, lack of objectivity in grading, etc., students should follow the process outlined below.
- Discuss the specific complaint and your desired resolution with the faculty person.
- If talking to the faculty person fails to bring resolution, you may meet with the Department Head and present a concise, well-thought-out, written statement of the problem and the desired resolution.
- The Department Head will offer to meet with you and the accused faculty person. If you are unwilling to attend such a meeting, your complaint will be considered dropped. If you consent to the meeting, then the Department Head will be responsible for documenting the proceedings and the outcome in writing.
- The accused faculty person or you may request a second meeting within seven days to which both the faculty person and you, within the limits set by the Department Head, may invite colleagues and students. The Department Head, at his/her discretion, may request the presence of the Dean of the Degree Completion Program.
- If the problem is not resolved to the satisfaction of either party, a written appeal may be made to the Vice President of Academic Affairs who is empowered to make the final decision. The Vice President of Academic Affairs will respond with a final decision in writing to those involved.
Appeal Procedure
Occasionally a student may wish to appeal an academic action such as a grade, a graduation requirement, or a withdrawal penalty. Such appeals should be made in writing to the Dean of the Degree Completion Program. In most cases the student should first request the support of their Department Head.


text:
The Fire
While one of her friends cried heavily into her shoulder, Sorrow watched her ten year old reading quietly, often sparing a glance at Sharon and his mother.
There was nothing worse for Sorrow when sharon broke up with someone. She would sit for hours, ranting and crying, before drowning herself in alcohol.
This lasted till one in the morning, where Sorrow refused to stay in the same house as her drunken friend. Making their way back, Alex grabbed hold of his mother's arm tightly.
"No. Stay here." he whispered, peeking round the corner carefully. Sorrow herself looked, and found herself in dismay.
"No sign of them, sir." A man reported to another, infront of the burning building. The fire licked up, covering the walls with black, until it began to crack and crunch, falling, bit by bit.
Alex pinched his mother, bringing her out of her stupor. "We gotta run." He told her, puling at her to follow him. The two ran, inbetween houses, through back gardens.
"Go check over there!" Came a shout. A man came into view. Alex morphed his hand into a gun, aiming carefully. He shot the man twice in the legs, before his and Sorrow began to run again. Following her son to a house, with broken windows, and a door with two boards nailsed to it, she watched him beat out a rythmic pattern. The door was pulled open, and they were pulled inside.


text: CH 1: Two Roman Girls Part of Speech and Latin Sentence Structure Salvete, discipuli et discipulae Salve, Magistra Quid nomen tibi est? Mihi nomen est… Mihi placet. Ubi est Adsum. Abest. ? Chapter 1 TWO ROMAN GIRLS Ecce! In pictūrā est puella, nomine Cornēlia. Cornēlia est puella Rōmāna quae in Italiā habitat. Etiam in pictūrā est vīlla rūstica ubi Cornēlia aestāte habitat. Cornēlia est laeta quod iam in vīllā habitat. Cornēlia iam sub arbore sedet et legit. Etiam in pictūrā est altera puella, nōmine Flāvia. Flāvia est puella Rōmāna quae in vīllā vīcīnā habitat. Dum Cornēlia legit, Flāvia scrībit. Laeta est Flāvia quod Cornēlia iam in vīllā habitat. 5 1. Who is in the picture? 2. Who is Cornelia? 3. What else is in the picture? 4. When does Cornelia live in the country house? 5. How does Cornelia feel about living there? 6. What is she doing? 7. Who else is in the picture? 8. Who is Flavia? 9. What are the two girls doing? 10. Why is Flavia happy? 1a. Responde Latine 1. 2. 3. 4. 5. 6. 7. Quis est Cornelia? Ubi habitat Cornelia? Cur est Cornelia laeta? Quid facit Cornelia? Ubi habitat Flavia? Quid facit Flavia? Cur est Flavia laeta? Let's Review •Latin has a more flexible word order than English. •The verb will usually go at the end of the sentence. •The adjective will normally come after the noun •Latin doesn't have articles ("a", "an", or "the"). •A present tense Latin verb can be translated 3 ways sedet: she sits, she is sitting, she does sit Let's Review (Con't) •Latin doesn't use helping verbs, such as is, am, do, does. It's built into the verb. •The girl is running. Puella currit. •When est is used, it's the only verb in the sentence. •Cornelia est puella. •Latin has the same parts of speech as English •Verbs adverbs prepositions •Nouns conjunctions articles •Adjectives interjections pronouns Nomen? Verbum? Adjectivum? In pictura est puella. nomen In pictura est villa ubi nomen Cornelia aestate habitat. nomen Corrnelia sub arbore sedet nomen et legit. In pictura est altera puella, nomine Flavia. verbum adiectivum nomen Dum Cornelia legit, Flavia scribit. verbum Answer the following questions after reading the Introduction on pages xii – xv of your text. 1. Who are the members of the family featured in our reading? 2. When do the readings take place? What important event occurred just prior to the readings? 3. What sort of place was Baiae? Who lived there? What do you think would be a modern equivalent? 4. English is considered to be a hybrid between Germanic and Romance languages. What are the other 5 Romance languages? What other languages do you think are Germanic? 5. How did Latin words come into English? What does English have that Latin does not? Quis est puella? Puella est Cornelia quae aestate in villā rusticā habitat. Cornelia in villā rusticā est laeta quod sub arbore legit. In villā vicinā habitat altera puella Romana, nomine Flavia. Hodie Cornelia in villā sedet et legit. Ubi est Flavia? Ecce! Etiam in villā sedet Flavia. Quid facit Flavia? Flavia scribit dum Cornelia legit. Flavia est laeta quod in villā scribit. Parts of Speech The boy yelled, "Help!" and he saw a brave dog quickly run to the rescue. Noun Pronoun Verb A noun is the name of a person, place or thing. A pronoun is used in place of a noun in a sentence. A pronoun may take the place of the name of a person, place, or thing. A verb tells what action someone or something is doing, or it can express a state of being. Person girl boy teacher Place school home store Thing pencil jacket dog I you he, she, it we you they (y'all) Action run jump sit ask think talk State of Being am is are was were Adjective Article Adverb An adjective describes a noun or a pronoun. An adjective tells what kind, how many, or which one. The words a, an, and the belong to a special group of adjectives called articles. An article can be used before a noun in a sentence. An adverb describes a verb, adjective, or another adverb. An adverb tells how, when, where, or to what degree. What Kind happy brave How Many more six Which One this that A a dog a rabbit An an apple an ant The the boy the bird When today How Where To What Degree quickly outside barely Preposition Conjunction Interjection A preposition combines with a noun or pronoun to form a phrase that tells something about another word in a sentence. It very often refers to location in time or space. A conjunction joins together single words or groups of words in a sentence. An interjection expresses strong feeling or emotion. An interjection can be a single word or a phrase. from over to with until after and but or nor Help! Ugh! My goodness! Oh! Whew! Look out! Ouch! Ah! Oh dear!