text:
3 The Covenant
"Come on, let her make a mess a little bit longer. She's so sweet!" My godmother cheered me on as I demolished my birthday cake, feeding myself without the benefit of fork or plate, and shoving cake into the mouths of anyone who'd get close enough. My godmother shot a look at my dad, convinced of her victory over his unspoken disapproval. Everyone was laughing except him. It was another hazy day in June of 1972, hot and humid, when the jersey was in fashion and women wore flounced skirts.
My birthday party took place in Kralja Aleksandra Street. The house was too small for such a large gathering, and the guests spilled out into the dandelion-strewn yard. Nobody seemed to mind. Though chaotic, everything looked just the way that it should—if you didn't consider the mess I was making of the cake.
"She's five now, and this is the last time she'll be allowed to do something like this," my godmother said. Happy as I was with my powerful ally, I continued to poke around in the cream cake.
And then my father spoke, his deep clear voice filling the room. "Maria," he scolded, "I've told you she simply can't do whatever she wants, whenever she wants. She must learn to behave." Dad clearly was not happy with my behavior. Even at my young age I could tell I'd overdone it.
There was tension in the air, sparks were ready to fly between Dad and my godmother. A clash was imminent. I looked up inquiringly, and his sour smile indicated that he was hesitant to administer punishment on my special day. My stubborn look and his frown were two whirling storm clouds which would produce lightning if they came into contact. It would be several years before the storm reached its climax.
Suddenly, with a deep sigh, he stood, gave my godmother a stern glance, and grabbed me up in his arms. He took me away resolutely to another room, as if to say, "This is my house and my child, and I will have the final word."
"I warned you to stop," he said, as he closed the door, still holding me in his arms. Then, he let me go.
My heart thumped with fear as I fell, feeling each fraction of a second as though I were a discarded toy tossed into a corner. I landed on a big feather pillow, over which my dad had dropped me. I felt as if I'd been thrown away like so much trash. My heart continued to pound—now more with sorrow than fear—as my father walked out of the room and slammed the door behind him.
In a few minutes he returned, and behind him, framed by the doorway, I saw the faces of all my concerned relatives. Dad picked me up and held me for at least half an hour. As I lay wrapped in his arms, I knew that he was no longer interested either in the guests or my spoiled behavior. He only cared that I not be unhappy. By the tears I saw in his eyes I knew that he was terribly sorry for what he had done.
"That's the first and last time I will ever hurt you," he said. "I swear."
These were the words of a new covenant of love established between us. He admitted as much as he was putting me to bed a few nights later. It reestablished my sense of security, and total peace flooded my heart. I was happy again, and thankful for my parents, whom I adored. I soaked up the love offered by my dad. No matter what problems I might face in life, I felt sure again that I could rely on him. I closed my eyes and fell peacefully asleep.
But while I slept, ominous shadows squeezed through the cracks of my fairy-tale world. They mocked my carefree existence, and seemed to ask, "Will Daddy really honor the promise he gave you?"


text:
Spazz: Dwarf Jester Rising (Scene Support Edition) 12"
625 Thrashcore Records
Repressed on purple splatter vinyl! The debut LP from SPAZZ originally released more than 20 years ago in 1994! The rarest of the SPAZZ LPs, "Dwarf Jester Rising" is SPAZZ's most stripped down and raw full length, re-mastered and re-released by 625 for all of the vinyl addicts out there. Scene Support Thrash Pack comes with free copies of the FLIPOUT A.A - Non Fiction 7", EURO THRASH RETRIBUTION- CD comp, and surprise 625 7" (while supplies last). Limited to 150 copies.Tags: 90s hardcore power violence reissues

subset: commoncrawl


text: This report identifies 109 candidate antibiotics in the clinical pipeline, approximately 70% of which are in early development (Preclinical and Phase 1). In contrast, there are just 9 candidates at Phase 3, while there are 31 at Phase 2. These pipeline developments are being progressed by 66 companies, of which nine (14%) are major international corporations and 57 (86%) are Small/Medium Sized Enterprises (SMEs).Executive Summary Chapter 1 Introduction (p.18) 1.1 Antibiotic Resistance1.2 Resistance Mechanisms1.3 The Resistome1.4 Pathogenomics1.5 Strategies and Targets1.6 The Cost of Antibiotic Resistance1.7 Global Surveillance1.8 This Report Chapter 2 Antibiotic Resistance, Global Trends (p.27) 2.1 Antibiotic Resistance2.2 Europe2.2.1 Carbapenem-resistant Klebsiella pneumoniae and Pseudomonas aeruginosa (2005 to 2010)2.2.2 Escherichia coli 2.2.3 Streptococcus pneumoniae 2.2.4 Staphylococcus aureus 2.2.5 Enterococcus faecalis2.2.6 Klebsiella pneumoniae2.2.7 Pseudomonas aeruginosa2.3 Other Countries2.4 China2.5 USA2.6 Kuwait2.7 Discussion Chapter 3 Marketed Antibiotics (p.63) 3.1 Marketed Antibiotics3.2 Mechanisms3.3 Companies3.4 Sulphonamides3.5 Beta Lactams (penicillins, cephalosporins, carbapenems, monobactams)3.6 Aminoglycosides3.7 Tetracyclines3.8 Quinolones/Fluoroquinolones3.9 Macrolides3.10 Combinations3.11 Folate antagonists3.12 Mycobacterials3.13 Glycopeptides3.14 Others3.15 Discussion Chapter 4 Pipeline Antibiotics (p.86) 4.1 Pipeline Antibiotics4.2 Companies4.3 Phase 34.4 Phase 24.5 Phase 14.6 Preclinical4.7 Discussion Chapter 5 Discussion (p.106) 5.1 Background5.2 Mechanisms5.3 Multiple Activities5.4 Marketed Antibiotics5.5 Antibiotics Pipeline5.6 Circumventing Resistance5.7 Resistance Mutations5.8 Virulence5.9 Conclusions References (p.120) Tables Table 2.1 EARSS Surveillance Programme: Countries and Country codes Table 3.1 Developers or companies with marketed antibiotics for bacterial or fungal Infections (Source: Biopharm Reports, 2013). The top 11 companies are indicated in blue Table 3.2 Approved/marketed sulphonamide drugs, which exert their bactericidal effects through folate inhibition (Source: Biopharm Reports, 2013). Table 3.3 Approved/marketed beta lactam antibiotics, which exert their bactericidal effects through the inhibition of cell wall synthesis (Source: Biopharm Reports, 2013). Table 3.4 Approved/marketed penicillins, which exert their bactericidal effects through the inhibition of cell wall synthesis (Source: Biopharm Reports, 2013).


text:
- Fours
- Sixes
- Wickets
- SR Watson 22
- PJ Hughes 12
- RT Ponting 44
- MJ Clarke 23
- MEK Hussey 95
- UT Khawaja 21
- BJ Haddin 24
- MG Johnson 14
- RJ Harris 1
- TA Copeland 12
- NM Lyon 0*
- UWMBCA Welegedara 1/61
- RAS Lakmal 3/55
- HMRKB Herath 3/54
- S Randiv 2/76
- TM Dilshan 1/22
- Overs 1-50
- Overs 51-100
Herath to Watson, OUT, and he strikes first ball! Or does he? Yes, he does. This ball is six overs old, and turns a mile when tossed up by Herath. Watson pushes forward to defends this, the ball pitches short of a driving length, around off, and then breaks away and bounces to take the edge - a healthy one - through to P Jayawardene, who is the best wicketkeeper to spin bowling
SR Watson c †HAPW Jayawardene b Herath 22 (25m 19b 5x4 0x6) SR: 115.78
Lakmal to Hughes, OUT, What a pitch! What a beauty this Test could be. Takes off, explodes, from short of a length. It's close to off, and Hughes is committed to playing at it. The extra bounce means he has to fend at it, and it takes the shoulder of the bat before lobbing to slip. He didn't even run his fingers across this one. Let me remind you this is just the 10th over. Vicious bounce there from a length
PJ Hughes c Paranavitana b Lakmal 12 (39m 31b 2x4 0x6) SR: 38.70
Herath to Clarke, OUT, Review time. Clarke is not picking the arm balls. Again pushes forward, plays for the non-existent turn, and is beaten comprehensively. Prasanna Jayawardene is so sure this is out he doesn't even look up and starts running towards the bowler. Umpire Kettleborough, though, still thinks it's not out. Sri Lanka go for the review this time, and replays show this is hitting the middle of middle stump, and Clarke hasn't even got outside the line of off. Couldn't have been plumber had he been fixing pipes. Strange he wasn't given out originally
MJ Clarke lbw b Herath 23 (60m 45b 2x4 0x6) SR: 51.11
Herath to Ponting, OUT, Gone! Yet another start by Ponting left unconverted into a big one. Just like the last over, Ponting comes down the track and wants to go straight over Herath's head, doesn't quite get close to the pitch of the ball, this one turns more too, making him go inside out The mis-hit stands up in the air, the mid-off is deep enough to take a comfortable catch
RT Ponting c Mathews b Herath 44 (114m 83b 6x4 0x6) SR: 53.01
Welegedara to Khawaja, OUT, Reverse swing! Timber! Khawaja's tentative stay ends. He has always shown the bowlers a tempting gap between bat and pad, and this time Welegedara sneaks through it. This is just short of a yorker length, Khawaja drives away from the body, and the late swing squeezes in to hit the stumps
UT Khawaja b Welegedara 21 (68m 58b 0x4 0x6) SR: 36.20
Randiv to Haddin, OUT, Sharp offbreak, sharp catch! This is quick, turning in sharply, Haddin turns it around the corner... around the corner is Mathews at backward short leg who takes a smart low catch in front of him
BJ Haddin c Mathews b Randiv 24 (44m 46b 3x4 1x6) SR: 52.17
Lakmal to Johnson, OUT, soft soft dismissal after many much more menacing deliveries! This is short and wide, going wider, but Johnson goes for the pull as opposed to the cut, and gets a faint bottom edge through to PJ. It was so innocuous the slips didn't even realise he had edged it!
MG Johnson c †HAPW Jayawardene b Lakmal 14 (36m 33b 1x4 0x6) SR: 42.42
Lakmal to Harris, OUT, Finally they get an lbw out of Kettleborough. This takes a long internal deliberation, though. This is short outside off, Harris doesn't offer a shot, the ball seams back in sharply, and hits him just under the knee roll, just outside off. Because he was not playing a shot, the point of impact was irrelevant. To me, it looked like it would have the the top of off. Kettleborough takes his time before sending Harris on his way. Harris mulls a review, but doesn't ask for it. I tell you what, the ball projection shows this didn't come back in to hit the stumps! Even if Harris thought he was out, he should have gone for that strategic review
RJ Harris lbw b Lakmal 1 (8m 5b 0x4 0x6) SR: 20.00
Randiv to Copeland, OUT, Sharp turn, simple bat-pad catch. This is flighted, draws Copeland forward, who looks to play this to leg, is not close to the pitch of the ball, gets an inside edge onto the pad, and an easy catch accrues for short leg
TA Copeland c Paranavitana b Randiv 12 (21m 16b 3x4 0x6) SR: 75.00
Dilshan to Hussey, OUT, Given leg-before! Again it's the straighter ball from an offspinner that has done the damage here. This pitched outside off, Hussey defended, playing for the spin, the ball went on with the arm, hit the pad, right in front of off. Kettleborough took his time, then raised the finger. Hussey reviewed it just in case. Replays say there is no just in case here
MEK Hussey lbw b Dilshan 95 (246m 177b 7x4 3x6) SR: 53.67
- Overs 1-50
- Overs 51-100


text:
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Browse through the list of Orcieres hotels to find the right hotel at a great price. Each hotel in Orcieres has many photos, reviews and a map of its location in Orcieres to make sure you get the most out of your stay. Booking your hotel in Orcieres couldn't be simpler. Just find a hotel, check the rates and proceed to the checkout. We'll have you enjoying your Orcieres hotel in no time. Quick, easy and secure.


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Dacheng3d.com is a 2 years old domain.
It was registered by Chen Brian , who can be reached at . The site is owned by Brian Chen. Registration details show that it was registered on 30 Nov 2014 through xin net technology corporation and will expire on 30 Nov 2015.


text:
Damian is a brilliant haematologist who always has time for his patients. He is never impatient and has a rare ability to make a patient feel like you are his one and only special patient. I always value his advice and nowadays five years into treatment for CML I just get on with life for if he is not concerned then why should I be.
Short link to review Dr Damian Finnegan: http://iwgc.net/efax4


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from $401 / night help Price for guests, Nights
Detached private 5 bedroom villa. – Home 7816957 Villa
- 5 bedrooms
- 10 sleeps
- 7 nights min stay
Detached private 5 bedroom villa. – Home 7816957
- Villa
- 5 bedrooms
- sleeps 10
- 7 nights min stay
Top Review
Villa / 5 bedrooms / 6 bathrooms / sleeps 10
Key Info
- Swimming pool
- Child friendly
- Air conditioning
- No pets allowed
- Private garden
Description from owner
This is a 4 double bed detached villa with an adjoining 1 bed self contained apartment.It is private and quiet with its own pool.Minutes walking distance to the excellent restaurants of Benahavis village.The property benefits from a fully equipped gym and a games room with a 3/4 size snooker table..
- Great for children of all ages
- No pets allowed
Bed & bathroom
- Bedroom 1: Queen Bed
Bedroom 2: Full bed
Bedroom 3: Full bed
Bedroom 4: Full bed
Bedroom 5: King bed
- 5 En suites, 1 Toilet Only
- Wi-Fi available
- Air conditioning
- Private outdoor pool (unheated)
- Private garden
- Internet access
- Satellite TV
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- Parking
- Secure parking
- Not suitable for wheelchair users
- Check in time:16:00, Check out time:10:00
- If you have any questions about check-in or check-out times, please contact the owner/manager.
- Payment
- This rental can only be paid for online through Holiday Lettings using your credit/debit card or PayPal (never by bank or wire transfer).
- Smoking
- No smoking at this property
- Cancellation policy
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About the owner
Chris W.
Tourist License
Prelimary Number:5082
- Response rate:
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- Calendar last updated::
- 25 Apr 2017
Languages spoken: English
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Generali Second-Quarter Net Climbs 74% on Non-Life BusinessSonia Sirletti and Francesca Cinelli
Assicurazioni Generali SpA, Italy's biggest insurer, said second-quarter profit rose 74 percent as higher non-life earnings outweighed a drop at its life business.
Net income climbed to 478 million euros ($634 million) from 274 million euros a year earlier, Trieste, Italy-based Generali said today. That matched the average estimate of six analysts surveyed by Bloomberg.
Chief Executive Officer Mario Greco is selling non-strategic assets and refocusing on Generali's core business to strengthen finances and boost profitability. The insurer is more than half way to its goal of raising 4 billion euros from asset sales by 2015, after selling its U.S. reinsurance unit and Mexican businesses.
"Generali published mixed results," Raphael Caruso, an analyst at Raymond James Euro Equities, wrote in an e-mailed report to clients. "Earnings were supported by the strong performance of the non-life insurance segment. Nonetheless, the life insurance segment's earnings were significantly hampered by low investment results."
Generali shares declined 0.9 percent to 14.68 euros as of 11:49 a.m., giving the company a market value of 22.9 billion euros. The stock has advanced 6.8 percent this year compared with the 16 percent gain in the 30-company Bloomberg Europe 500 Insurance Index.
Italian Operations
"We have taken significant strides in strengthening our capital position and improving our operational and financial performance," Greco, who took over as CEO last year, said in a statement. "Generali is more focused and profitable than it was a year ago and we are well on track to achieve the targets we have set ourselves," he said, reiterating that Generali expects to report higher operating results this year.
Generali yesterday replaced Raffaele Agrusti with Philippe Donnet as CEO of its Italian operations, which are being restructured.
"The Italian unit restructuring starts now a new step to develop business, which will require several years," Greco said on a conference call. "It was the right move to have a manager with long-term prospective."
Greco said Generali's 6.8 percent stake in Telecom Italia SpA, Italy's biggest phone company, is among the assets that will be sold " under right conditions." Generali, which is the second-biggest shareholder of Telecom Italia, may consider exiting Telco SpA, the group controlling the phone company in September, even if "no decision has been taken yet," Greco said.
BSI Sale
The Italian insurer is also selling its Swiss asset-management unit BSI Group as part of a plan approved in January.
"BSI is a good asset and we want to sell non-core assets at the right price," Greco said. "There is a complicated market at the moment, so a sale at a fair value takes time, requires negotiating, and this is what we are continuing to do."
Bankinter SA of Spain may buy BSI, CEO Maria Dolores Dancausa said in April. The firm offered 1.5 billion euros in partnership with U.S.-based Apollo Global Management, Swiss newspaper L'Agefi reported in March. Generali has said the unit has a book value of 2.3 billion euros.
"The company is on track to achieve attractive earnings growth and returns, driven by the ongoing restructuring," Michael van Wegen, an analyst at Bank of America Merrill Lynch, wrote in a note to clients. "Although the Italian macro remains challenging, in our view Generali still is an attractive investment case for investors comfortable with exposure to Italy."
Mixed Results
Non-life operating profit increased 23 percent to 389 million euros as the insurer reduced costs. Claims and costs as a proportion of premiums, known as the combined ratio, improved to 94.7 percent in the first half from 97.1 percent a year earlier.
Total operating earnings rose 1.7 percent to 1.05 billion euros in the second quarter from a year earlier as profit at the life business fell almost 13 percent to 683 million euros.
Generali's solvency ratio, a measure of its capacity to absorb losses, rose to 139 percent by June 30 from 130 percent a year earlier, the insurer said. As of mid-July, the ratio was 142 percent, excluding a contribution from the sale of Mexican minorities and U.S. assets, the company said.
Generali was one of nine insurers designated systemically important by global financial rule makers last month, which may mean it will face tougher capital standards and tighter regulation. Greco said today the implications of being a systemically important insurer aren't clear and that the company may not be included on the list in the future.
Generali was put on the list because of its non-insurance activities, said Greco, adding that "the position in that list might change over time as they are focusing on core insurance activities, and disposing of non-core assets."


text:
Chapter 1: The Girl in the Bag
"Fwaah! We sure pigged out, eh? I love chowing down after a job! It adds to the flavor, I swear!"
Distorted voices floated through the rough burlap surrounding her. Male. Two of them.
"Heheheh, yeah. And we bagged ourselves a great big catch, too. Boss'll be sure to fix us up good with big rewards, too."
She tried to clear her head. So many questions floated in her head. What had hit her? What on earth had happened? Why was it so hard to remember? How had she ended up in a sack with tape over her mouth and her hands and feet tied together behind her back?
That seems like a good one to start with she thought.
There was the slamming of two doors and the turn of a key.
"Heheheh, it doesn't get any better than this!"
Best to start from the beginning. My name is Rui Noel. I live in the Kanto region with my cousin, Misty.
"Come on, come on you engine. Start!"
I came to Orre to see my grandparents, Eagun and Beluh. They live in Agate Village and are probably worried sick about me.
There was the roar of an engine and the metal floor she was lying on (a truck bed, if she had to guess) began to vibrate.
I got lost. I should have gone north but I went east instead. Curse that faulty GPS!
It sounded like they were moving, though it was kind of hard to tell. She couldn't see, couldn't speak, couldn't move. This was going to get unbearable pretty soon.
"Hey, Trudley! I just got a message from the boss!"
I ended up in Pyrite Town. I saw these two creeps. One had a weird hat, the other had yellow hair with red streaks.
"What's it say, man?"
They had a pokémon... a fighting-type, I think. There was something... odd about it.
"He wants to know, and I quote-"where on the shiny disco ball that is this movin', groovin' party house of a planet"-end quote, are we."
That pokémon wasn't just fighting regular trainer battles against other pokémon... it was attacking people!
"Blast it! He noticed we're late!"
I could also see something else about it. It's aura was… black.
The bumping increased as the truck picked up speed.
"Of course he noticed we're late! We were supposed to go back to Pyrite, not halfway across Orre!"
I've seen a lot of pokémon auras of course, ever since I was little, and the ability's been in my family for generations, but… While each aura is slightly different, I've never seen black before. It felt as though its heart was cold and empty. It scared me.
"Well, it's not my fault that girl's GPS couldn't find sand in a desert! Why did we ever use that thing?"
I went to that policeman... Officer… Johnson, I think?
"Fine. From now on, we won't use free electronics people we're kidnapping just happen to be carrying around. Happy?"
He didn't believe me, but his shouting alerted those two and they ran off.
A strange musical and very rhythmic beat began, even cutting through the sound of the air rushing around the moving truck.
"Drat! He's calling! What do I say, what do I say!"
I felt like I needed to get out of Pyrite right then. I got back on that rental scooter and just drove.
"Uh, hi, boss. How's it going?"
I guess they followed me. It seems like whatever is wrong with that pokémon, no one is supposed to know about it.
"'How's it going?' You idiot! You'll get us fired! Give me that!"
There was what sounded like a brief struggle and what may or may not have been a slap fight.
"Uh, yeah, boss, we got that girl. Just like you told us. She, uh... made it further than we anticipated. But we got her now and we're heading back to the hideout. Uh, yeah. We're actually out south of Eclo Canyon, as it turns out. Like I said, she is really fast..."
That little rental scooter couldn't possibly outrun their truck. They bumped me off the road not long after the chase started.
"Uh, no, boss! We didn't get lost! What possibly gave you that idea?"
I think my scooter went off a cliff after I fell off. I guess I could say I'm lucky that I didn't follow it… but I sure don't feel that way, tied up in a sack and all.
"Uh, yeah. We'll meet you there. Bye!"
I guess they grabbed me while I was out, and really don't want me escaping.
"Okay, it sounds like we aren't fired. Yet."
There was another bump. Harder now.
I need to find a way out of here. I don't think these guys are planning to invite me to tea.
"No thanks to you, genius. So we need to get this girl to Oasisville, huh?"
What did they do to that pokémon! And why is it so secret that no one can know about it? What is going on here?
"Yeah. Miror said he'll have some guys meet us there."
Let's face it. They're going to kill me, aren't they? They're going to kill me and there's nothing I can do about it.
"Well, Folly, buddy, let's go! Step on it!"
No! Rui, get a hold of yourself! She was practically shouting inside her head, using an authoritative tone like what her mom used to use. Don't give up! You aren't dead yet, and until you are, you can escape!
"I am stepping on it, you idiot!"
You have to escape, and tell someone about this! Help stop whatever's going on here! And you better do it while it's just these two idiots and not their boss as well!
"Well, step on it harder! Go!"
Okay, okay. Escaping. Just like they do all the time in the movies. I really should have watched more of those movies. Let's see here. First, I guess I'll need to get out of this sack…
"Well, I guess it's not like it's our truck or anything. Stepping even harder!"
Aw, let's face it, I have no idea how to untie myself and get out of this sack. Great.
The truck accelerated and began hitting rocks again and again, creating a bumpy environment not optimal for thinking in dangerous situations.
Well, one step at a time. Being able to feel my arms would be nice.
But they were tied together at the wrists with pretty thick rope. She would never be able to break that.
Unless, if the knots aren't perfectly tight…
She began twisting and pulling her arms, trying to find any weakness in the knots, which by the sound of it, her captors would be dumb enough to leave. And, as it turned out, there was a little slack that felt like it could be manipulated. Yay.
Well, I guess this is as good of a plan as I'm going to get. I hope it works before we get wherever it is we're going and I learn what these guys have planned for me…
As it turned out, it wouldn't be that long of a wait.
Hey there, just the beginning of my first pokémon fanfic, For Want of a Knight. This is based on the game Pokémon Colosseum, and asks that eternal question: What would have happened to Rui if Wes hadn't come along at the perfect moment to rescue her?
I'll probably update this fairly frequently, but the first few chapters will probably be pretty short.
I hope you enjoy. Please let me know if there are any typos or other things that need fixing.


text:
It only takes a minute to get started. Fill out our uncomplicated sign up form and login to the website.
This step is optional but will dramatically increase your chances of getting interest from other Christian members on the site. Write a few sentences about yourself, your interests and upload any nice photos of yourself.
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Located someone who ticks all the boxes? Drop them a line or just a wink and wait for their response. With a little luck you'll be on your way to discovering your soulmate.
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text:
For the past few weeks, there have been discussions that the Federal Government is considering adding Health & Dental benefits to the list of taxable items for individuals. This would result in a large tax burden to all group benefits plan participants and many will struggle to maintain current levels of quality care. This is a significant tax imposition to employees if implemented by the Federal Government. In addition, some employers may decide to scale back on their programs if the tax is implemented.
A number of associations have come together to address this issue and the OAC has offered to help in this regard.
A website has been set up through which members and their staff can have their say to prevent this tax proposal from happening. The site is www.donttaxmyhealthbenefits.ca and we encourage you to visit it today and share the link to reach as many people as possible.
The OAC will also be writing to the Minister of Finance about the issue and liaising with the noted group of associations as well.


text:
Perfect waterfront getaway! Home offers 2 bedrooms 1 bath all on the main level. Open concept Kitchen/living and Dining area. Free standing wood burning fireplace, main floor laundry and a screened in porch overlooking the lake. There is even a 2 car garage to store all your toys! Property is being sold "as-is" and is subject to HUD guidelines 24 CFR 206.125 JVBS
Features Residential
|Style: 1 Story
|Lake Chain:
|Garage: 2 Car, Detached
|Lake Name: Korth Lake
|Year Built: 0
|River Name:
|Basement Type: Crawl Space
|Water Frontage (feet): 200
|Fin SqFt Total: 1,122
|Lake Size-Acres: 21
|Lot Size: 73616
|High School: VI Northland Pines
|Site Influence: Lake Front
|School District: Northern Pines
|Construction: Frame/Stick
|Short Sale/Foreclosure: Foreclosure


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20642 Elkview Road, Richmond, MN 56368
About the Listing
Stunning views from massive, maintenance free wrap around deck, this 3 bedroom, 2 bath year-round walkout rambler has no exterior home maintenance, updated interior with granite counters, stainless steel appliances, master suite with fireplace. Lower level family room walks out to lakeside. The triple door pole shed is insulated & heated.
Share Listing
Property Details for 20642 Elkview Road, Richmond, MN 56368
Bedrooms: 3
Bathrooms: 1 Full | 1 Three-Qtr
Lot Size: 0.54 Acres
Lot Dimensions: 146x239x50x258
Year Built: 1967
Garage Dimensions: 3 car
Garage: Detached Garage, Insulated Garage
Style: (SF) One Story
Water: Well
Sewer: Private
Square Feet: 1792
Above Ground Sq Ft: 1280
Below Ground Sq Ft: 512 (approx)
Room Information for 20642 Elkview Road, Richmond, MN 56368
Main Floor
Living Room: 15x19
Dining Room: 12x17
Kitchen: 12x15
Bedroom 1: 12x16
Bedroom 3: 9x9
Lower Floor
Family Room: 14x18
Laundry: 10x10.5
Dining Room Description: Kitchen/Dining Room
Family Room Characteristics: Lower Level
School Information for 20642 Elkview Road, Richmond, MN 56368
School District: Rocori
School District Phone: 320-685-4901
Interior Features for 20642 Elkview Road, Richmond, MN 56368
Appliances: Range, Microwave, Dishwasher, Refrigerator, Washer, Dryer, Water Softener - Owned
Air Cond: Central
Heating: Forced Air
Fireplaces: Yes
Basement: (512 sq Finished) Walkout
Exterior Features for 20642 Elkview Road, Richmond, MN 56368
Lot Description: Tree Coverage - Medium
Lot Dimensions: 146x239x50x258
Roof: Asphalt Shingles
Zoning: Residential-Single
Financial Considerations for 20642 Elkview Road, Richmond, MN 56368
Tax Amount: $2,468
Taxes w/Assessments: $2,468
Tax/Property ID: 23140420000
Tax Year: 2016
Monthly Payment = $0
INRIX Drive Time
Calculate Your Drive Time From This Property
Similar Listings For Sale
The data relating to real estate for sale on this web site comes in part from the Broker Reciprocity Program of the Regional Multiple Listing Service of Minnesota, Inc. Real estate listings held by brokerage firms other than the owner of this website are marked with the Broker Reciprocity logo or the Broker Reciprocity thumbnail logo and detailed information about them includes the name of the listing brokers.


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Tastings & Tours
- Bucks County
- and Surrounding Area, PA 18951
- (484) 695-6465
Our special partnerships with the wineries and breweries provide you with affordable private tastings and discounts not normally offered to the general public. We handpicked and customized the "Tastings and Tours" just for you!
- Booking Notes: Must be legal drinking age.
- Cancel policy: INDIVIDUAL CANCELLATIONS: A non-refundable $20 processing fee applies to each individual's reservation. If your reservation is cancelled 5 days or more prior to your scheduled tour, the balance of your fees (minus the $20 processing fee per person) will be refunded. Your event can be rescheduled if done 5 days or more prior to your tour date, and your entire payment (including the $20 processing fee) can be applied to another event within3 months of the original tour date (all fees are non-refundable once a tour is rescheduled). Visit website for GROUP (3 or more individuals) CANCELLATION POLICY.
- Credit Cards Accepted:
- Days & Hours of Operation: Tours by reservations only. Pick up and drop off time varies due to the number of people and pick up locations. Approximate pick up is 11am with a drop off at approximately 5:30pm.
- Deposit policy: We will require a final count and payment for the group at least 2 weeks before the tour date.
- Payment Policy: T&T dates are reserved when paid in full online or by phone. All last minute reservations booked within five (5) days or sooner of the tour date must be paid in full with no refunds or rescheduling allowed.
Group Tours
- Guided Tour - Min/Max Size: We require a minimum of 6 for tours Sunday through Friday. Saturdays are open to any size group.
Facility Info
- Description Let us help plan your perfect corporate event. We can create and customize any package to suit your schedule and budget. Our standard wine package is available which includes VIP tastings, tours and lunch or we can work with you to create your own unique day. We can combine a winery and brewery experience or perhaps an afternoon tour followed by a wine pairing dinner or even a BBQ! We can even arrange tours and tastings at historic landmarks such as Fonthill Castle in Bucks County! There is no limit to what we can do to make your next corporate outing a huge success!


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11. aryst0krat
My Present
My friends got me a present, you know!
They wrapped it with a nice red bow!
Inside was the answer to my prayers!
Inside, beneath those bright red layers!
Inside I'd find the thing I need!
Inside, from evil I'd be freed!
With my new present, the places I'd go!
My precious present, in a pretty red bow!
The present was hidden in the town;
I had to search it up and down!
They sent me on four treasure hunts,
Those lousy good for nothing---
I found my present, I'll have you know!
I found it and its big red bow!
The bow is bright, and shiny and...
The bow is... sticky? And hey, my hand!
It's stuck, but I'll... they got my arm!
This bow is losing all its charm!
The present was a trap, how low!
The present with its glue-like bow.
The gift's inside, and though I'm loose,
I know by now there is no use.
Bureaucracies are not good friends.
I hope they meet with gruesome ends.
Keep my present, I'll just go!
Red tape is not a good red bow!


text:
This is just a demo map that you can delete right away, if you feel like it...
Adoption studies have shown a correlation between IQ scores and biological parents.
Stimulating home environments can influence intelligence.
This is possibly due to biological differences in the brain.
This can be a result of; nutrition, parent involvement, amount of parent knowledge and/or skills, educational opportunities and resources.
The great majority of children are intelligent in their own way.


text:
Wilsons Insurance Agency
Call to quote: (912) 754-6496
What We Offer
- Auto
- Snapshot
- Motorcycle
- Dirt Bike
- Moped/Scooter
- Snowmobile
- RV/Trailer
- Golf Cart
- Segway
- Commercial Auto
Contact Us
- 832 Laurel St
- Springfield, GA 31329
Office Hours
- Mon: 8:30-5:00
- Tues: 8:30-5:00
- Wed: 8:30-5:00
- Thur: 8:30-5:00
- Fri: 8:30-5:00
- Sat: 8:30-12:00
After Hours Contact
By appointment
Languages Spoken
- English
Email Wilsons Insurance Agency
Big discounts for good drivers. Snapshot is a small device you plug into your car to personalize your rate based on how, how much and when you drive. Drive safe for your first policy term, and you can earn a big discount that stays with you for as long as you stay with us. The average driver saves $150.* Join the millions of Snapshot drivers who are saving.
Ask your agent about Snapshot today.


text:
It looks like you're new here. If you want to get involved, click one of these buttons!
And sometimes, professional advice doesn't help either. There's just too many variables for anyone to be sure.
Is it your weight?
Is it your biometrics?
Is it your running style?
Is it your running style and trainers?
Is it your training? (Too much too fast?)
Is it some combination of the above?
Personally, I don't trust instore gait analysis tests, there's no evidence that this works. A big study was done on soldiers in the US where some were gait analysed and others weren't; the gait analysed soldiers were given appropriate footwear and the ones who weren't were given a neutral training shoe.
There were no difference in injuries, or the type of injuries.


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The Little Girl & Her DollMature
She gripped the rag doll in her fingers tightly. The room was a sterile white, you could clearly see that she was uncomfortable sat there. She just didn't seem to fit. Her little head hung down with shame and deep brown hair curled gently around her face as she cried.
She stared at her fingernails and the doll that she loved so dearly. The doll she had tucked into bed every night for three years; good old Jenny. She quickly noticed her fingernails were long and grubby. Something her mother would not approve of at all.
"Wash your hands Ayissa. Quickly now, don't make me help you."
Her mother was long gone, in fact Ayissa hadn't seen a friendly face in so long now that she must have forgotten that kindness exists at all. Jenny wasn't torn like her she was just covered in mud and dust and smelled like cabbage. Cabbage was not a good smell for Jenny. Ayissa loved that doll as if she was her child. It'd been so long now since she had been able to clean Jenny and more importantly herself.
How did she get so dirty? She appeared so innocent but dried blood had become crusted on her face. Her little blue dress was torn and splattered with a deep red. The little girl and her doll just sat there and waited never looking up or moving only for a shudder of tears that escaped Ayissa's cracked and broken lips. The men that found her were only a few steps away, their muttering traveled down the corridor with vengence. She didn't hear them now, she didn't want to hear them. They had been disgusted with her. They looked at her and her doll with pity. She was the girl and the doll that they all forgot.
But that didn't matter now. None of it did. They seemed to have gotten what they wanted now. She wasn't at home anymore, she wasn't anywhere remotely near. She wasn't able to sit out at night on her swing anymore, remembering what was once a reality. She wasn't able to play games any more or go to sleep at night and dream. Her freedom was gone. All that was to come was just a nightmare of a future that she didn't want and wasn't going to accept.
When the world changed she was the one that was left behind. The one no one cared for. The little girl and her doll.


text:
Bill Haas survives final-hole scare, wins Humana Challenge
(Reuters) - Bill Haas survived a scare at the final hole to earn a one-stroke victory over five players at the $5.7 million Humana Challenge in the California desert on Sunday.
Haas took the sole lead with a 10-foot birdie at the 16th hole at the PGA West Palmer course at La Quinta on his way to his second victory in the event formerly known as the Bob Hope Classic.
He carded a 67 to finish at 22-under-par 266 for his sixth PGA Tour victory, leaving the 32-year-old only three short of catching his father, Jay Haas.
Fellows Americans Matt Kuchar (67), Charley Hoffman (64), Brendan Steele (64), Steve Wheatcroft (67) and South Korean Park Sung Joon (65) tied for second on 21-under.
Kuchar had the best chance to get to 22-under, but he missed a 10-foot birdie at the par-five 18th.
Haas parred the final hole but it was anything but routine after he pushed his drive and his ball stopped in the short rough just a couple of inches above the lip of a bunker.
He took an awkward stance in the sand with the ball above his feet, almost at waist height, which left him needing to execute almost perfect contact to avoid potential disaster.
"I could have whiffed (missed) that shot," Haas told Golf Channel after choking down on an iron and successfully punching the ball 80 yards forward.
He eventually tapped in to secure the $1.026 million first prize in front of a gallery that included former U.S. President Bill Clinton, whose foundation is a partner in the tournament. Continued...


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Results 1 to 7 of 7
07-31-2014, 02:14 PM #1Member
- Join Date
- Dec 2010
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- 702
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- 958.4
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Porsche 911 GT3 RS revealed in new patent photos
The first patent photos of the 2015 Porsche 911 GT3 RS have surface online.
Discovered by Car Magazine, the pictures reveal the model will follow in the footsteps of the 911 GT3but adopt a muscular hood and wider, ventilated front fenders. Moving further back, there's double bubble roof, lightweight wheels and rear fenders from the 911 Turbo. The model also has a new engine cover and a sporty rear wing.
Inside, there's sports seats and a roll cage that resides where the rear seats would normally be located.
Porsche has been relatively coy about the model but it could use a 3.8-liter six-cylinder engine that develops more than 475 PS (349 kW). It will likely be paired exclusively to a PDK transmission which has been specifically tuned for use in the model.
Hit up the source link for additional photos
Source: Car Magazine
///A L E X A N D R E 1983 Photography///ALX1983.COM
07-31-2014, 04:56 PM #2Member
- Join Date
- Sep 2012
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- 1,848
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- 2,356.7
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- 24
Holy $#@! that looks like a cup car without stickers! This thing is gonna be so fkin beast! I need it///M5 LCI
"It's like the F10 is the 911 Turbo to the E60's GT3" -Pistonheads (M5 feature)
Patent photos leak out the design of the 2015/2016 Porsche 911 (991) GT3 RS and it will have rear engine intakes
It looks like some of the questions about the upcoming 991 GT3 RS have been settled thanks to these leaked patent photos. The first question was whether for the first time ever a production 911 GT3 RS model would have Turbo inspired engine intake at the rear. The answer is year. It looks like Porsche wants to make sure the engine gets cool air so that no embarrassing engine fire issues pop up again.
The cosmetic items are easy to spot. The intakes, the roll cage, the wider body work, the aggressive wheels, etc. The question remains as to what is under the hood. It likely is a mildly tweaked version of the 991 GT3 3.8 liter flat-6.
Rumors persist about a turbocharged powerplant but spy videos of the test car on the 'Ring sound like the high revving GT3 mill is under the hood. It is unlikely Porsche will turbocharge the GT3 RS as they never have before and where would that leave a potential 991 GT2?
Expect the official reveal with more details in the next few months.
08-01-2014, 07:24 PM #5Member
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I'm very excited for this thing. I will bet any amount of money that it will be NA...anyone wants to take me up on that, I will gladly take the other side.
I think it's going to be NA. The turbo stuff is just people pulling stuff out of thin air.
This thing will be amazing!
EURO 04 M3 Current Mods:GC DAs, Eibach Sways, PF RTAB's, RE RCAs, INTRAVEE II, Black Roundels, ///MFEST Badges, Depo's, Screen protector for NAV display, VCSL Bumper + Race Lip & CF Trunk & CF Rear Diffusor, DIETZ TV in Motion, SS= V1 Headers + catless pipes + X-Pipe + SS Sport Exhaust, Z8 Starter Button, Lamin-X, OEM CSL interior, OEM CSL Steering, OEM CSL Intake, OEM CSL Roof, MSS54HP + OEM CSL Tune, BBS CH's, LIGHTWERKZ, 355mm ST40 BBK, BW Oil Cooler....


text:
Trapped In Love 2
This ain't a game but you're winning,
I feel like i'm drowning when you're singing,
And this is only the beginning,
I need to get away from you.
You corrode my mood like it's a competition,
You like to bully me into submission,
To say i love you is a contradiction,
I need to get away from you.
When i see you i will be truthful,
And i won't cave in like usual,
Because you are too spiteful,
I need to get away from you.
The moment comes and i'm ready,
But i open my mouth and you hit me,
And i find myself scream "i'm sorry!"
I'll never get away from you.


text:
Sign up for exclusive offers
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Our gym isn't just one of the best you'll find in a hotel, it's one of the best you'll find in South Wales. Serious equipment, a great pool, fully-qualified staff and a great timetable of fitness classes. From the valleys and the hillsides, and the streets of the capital, South Wales loves our Cardiff gym.


text:
My husband found some outgoing bills of one of our neighbors in the bushes
during one of his many walks. I encouraged the neighbor to report it,
which he did. The Postal Inspector happened to be there and advised him to
always put his outgoing bill payments in one of the official blue postal
boxes or the outgoing in the Post Office to avoid ID theft. When a thief
has your outgoing check, he has your account number, the bank routing
number and your signature...they don't need much to set up a fake. So
sorry, I know this must have been a real pain. Hope you weren't out too
much. Many banks have a limit on your responsibility.
We are still in the middle of a terrible drought...worst one in 98 of the
last 100 years. Even if we have a wet winter, the weather people are
saying that it will take 10 years to recover and get back to normal because
our rain fall is fairly evenly distributed throughout the year rather than
in one season. September did bring us some rain but not enough to help the
ground water...if you dig down three feet, you hit bone dry soil. Right
now, the only thing that is helping is the TVA dam system...else, we would
all be out of water. I'm letting most of my plants survive on their own
and hope they make it. UGH.
> [Original Message]
> From: Johnson Cyndi D Civ 95 CG/SCSRT <email@example.com>
> To: <firstname.lastname@example.com>
> Date: 11/5/2007 10:45:12 AM
> Subject: RE: [CHAT] Everyone must be....
> Busy but alas, not gardening. I got one pot - one - into the greenhouse.
> Saturday morning husband sat down to do bills and discovered that early
> last month someone had stolen our outgoing mail, with paid bills in it,
> and was busy writing checks around town using our account. So we spent
> hours at the bank backtracking all that stuff and more hours online
> trying to make sure they hadn't gotten into anything else. I still need
> to make the police report. Did you know (I didn't) that they don't even
> need your checks? The ones that were cashed were complete fakes, they
> just put our account number on the bottom. And poor fakes at that,
> anyone who really looked at it would have seen the typos and weird
> lettering, but oh well. We are hoping they are small-time criminals
> since all the activity happened a few days after the theft and nothing
> in the last couple weeks. What a PITA.
> What gorgeous weather we are having! In the back of my mind is the
> little voice that says we need rain, but it's just so wonderful now...no
> wind, sun, temps in the high 70s. Beautiful. Sunday I went hiking for a
> couple hours and then we loaded up my horse and went out to where
> husband's horse is being trained and boarded. My sister met us there and
> we went for a trail ride. More dirt roads than trails, but we hadn't
> been out there before so at least we didn't get lost. The rabbitbrush is
> blooming now and we were surrounded by hundreds of acres of sunny yellow
> (don't get too close, it smells atrocious). Ah you can't imagine how
> pretty the day was.
> My sycamores are dropping leaves now, so I guess it's time to start
> raking. And my poor rhododendron looks awful. We had the water rationing
> last week so all the sprinklers were off. Only a week of not watering,
> and it wasn't seriously hot, but the poor plant looks really bad. I am
> now feeling irresponsible for keeping this cool woodland plant here in
> the desert, I've always been kind of smug about having one but now I
> wonder - given our water problems - if I should be keeping it. Well, if
> it doesn't recover now that we're watering again, problem solved.
> Everything else looks fine.
> Cyndi
> -----Original Message-----
> From: firstname.lastname@example.com [mailto:firstname.lastname@example.com] On
> Behalf Of james singer
> Sent: Sunday, November 04, 2007 9:59 AM
> To: Garden Chat
> Subject: [CHAT] Everyone must be....
> busy this weekend. Not much happening here. Kinda chilly when I got
> up--55 degrees--but that's relative, I guess. Started a bunch of
> cuttings of strawberry guava [Psidium cattleianum (aka P. littorale)]
> for a friend in India. Don't know if they'll root; apparently the
> cuttings can be somewhat stubborn. Interesting and odd thing about the
> plant: it's invasive in Hawaii's rainforest [where wild pigs spread the
> seeds] and in central Florida [where birds spread the seeds], but not
> here--and in fact, I can't get it to grow from seed for some reason.
> And my friend in India is batting zero-for-two trying to grow them from
> seeds also.
> If you've never seen this plant, it's a nice, large, multi-stem shrub
> with very nice stem color and contour--somewhat like crepe myrtle but
> without the peeling [and suckering]. The local library has several that
> have been trimmed up as small trees, and they're quite eye-catching.
> Island Jim
> Southwest Florida
> Hardiness Zone 10
> Heat Zone 10
> Sunset Zone 25
> Minimum 30 F [-1 C]
> Maximum 100 F [38 C]
> ---------------------------------------------------------------------
> To sign-off this list, send email to email@example.com with the
> message text UNSUBSCRIBE GARDENCHAT
> ---------------------------------------------------------------------
> To sign-off this list, send email to email@example.com with the
> message text UNSUBSCRIBE GARDENCHAT
To sign-off this list, send email to firstname.lastname@example.com with the
message text UNSUBSCRIBE GARDENCHAT


text:
Guest reviews
Overall rating
9.3 Excellent
Based on 37 reviews
Recent reviews
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Find reviews that mention:
Featuring free WiFi, Inn Delovoi Vizit is situated in Volgograd, 3.1 miles from Motherland Monument. Free private parking is available on site. Every room at this inn is air conditioned and has a flat-screen TV. You will find a kettle in the room. Every room has a private bathroom. Extras include bathrobes and slippers. There is a 24-hour front desk at the property. Volgograd Arena is 3.7 miles from Inn Delovoi Vizit, while River Port is 5.6 miles away. The nearest airport is Volgograd International Airport, 7.5 miles from the property.


text:
Komperdell Guide Foam Trekking Pole with Camera Mount - Anti-Shock $34.95 + $2.95 S/H @ sierratradingpostGet Deal
posted 48 years ago by
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text:
The Soprano Scholar
As he strode after Hathaway and Charles, Lewis caught snatches of their conversation.
"What subject do you do?" Hathaway was asking.
"Theology," said Charles, missing the wince of memory that passed through Hathaway's face. He knew this life well; he had once been at Cambridge training to be a priest.
He was a much better policeman by all accounts.
Lewis caught up with the taller men's paces at the door to the college. The porter behind his glass door, smiled at Charles as if he had not just been fighting another man. The porter's glance to the policemen was, however, much less than friendly.
"Hello?" He questioned them with more than the word.
"We're here for the, err, Vivaldi show. Yeah, we're a bit earlier than your expected lot, but we were…in the area." He jabbed his thumb behind him.
"Of course, sir, come on in. Charles, will you be attending the concert?"
"Verity's part of the choir, so I might," replied the boy.
They wandered into the lavish first quad (though Lewis was pretty certain that all the OxfordUniversity quads were so well made), a squat square of mown grass, surrounded by old stone that towered. Hardly living quarters. They didn't have the softness about them.
"The chapel's through there – where you'll be seeing the performance. It's quite big, in case you were about to make a comment."
Lewis closed his mouth and refrained from adding any more.
"Look, I'm sorry about earlier. Can I just go and freshen up? My room's in the Hive, that new area through the buildings there. It's quite easy to find."
"Go on," Lewis said.
As the boy scampered away, the Detective Inspector studied him. His nobility was in his body, not quite in his head.
"I don't trust him."
"I know you don't," Hathaway remarked. "We should keep an eye on him in case, but best just to alert the porter to any further trouble."
"What, that porter?"
"Good point. For now, can we just enjoy the Gloria?"
Lewis shrugged. "Whatever you want. I'd rather just settle in with some telly."
"These people here are just clever students. Just because we happen to pass a few exams, doesn't mean we're all snobs, you know," said Hathaway. He did have a point.
They slunk together into the labelled chapel door. The high roof slanted to a point on the inside as well as outside; wooden beams were broad and obvious in the otherwise stone architecture.
Amongst the typical solid pews was situated a portable organ – presumably belonging to the chapel itself; when Lewis craned his head (and saw that Hathaway was doing the same with an impressed look on his face), he spotted the grand organ behind him, melded efficiently with the shape of the building.
At the front of the chapel milled students dressed in their formal robes, black with a strip of red for the colours of St. John's. They were almost a swarm to the sight of Lewis. Again, most looked up at their presence, but then turned back to arrangement their seating in no time.
A woman swathed in white with no gown crossed over to them. Her pale hair reflected the shine from the electric lights above, and her hands were dainty. When the young woman spoke, her eyes sparkled to remind Lewis of a sunlit sky.
"Oh, you're a little early," she said in the light voice of something from Bambi.
"Guess who that is," he heard Hathaway hiss in his ear.
"Sorry, we are. Happened to be passing and all that."
"Oh." Cassandra Porter's fingers twitched at her opposite cuff. She was nervous.
Lewis sat and smiled at the girl, trying to make her feel welcome. "Is everything all right? All going well?"
Cassandra appeared startled that he would say something like that. Her fidgeting increased in almost robotic proportions, tapping here and twitching there. Lewis recalled to mind what Charles had said. Certainly, she wasn't batty, but she was not a settled soul, either.
"I have a question," said Hathaway, before Lewis could stop him. "How did you get the position of soprano so easily? Am I wrong in thinking that, even for a Choral Scholar, it is difficult to rise up without prior performances?"
Cassandra's eyes widened and heat burned from her white cheeks. "Oh, that's quite a question. Yes, a fair point: this is my first performance as a Choral Scholar. I guess it's not fair, either, but I one the place fairly, via audition. So, yes, sir, that's how."
"Thank you," Lewis said with another smile. "You'd better get back to it. I'm sure tonight'll be top notch."
Cassandra nodded her head and scampered off. When he had finished watching her, Lewis turned to Hathaway. "You didn't have to accuse her of witchcraft. I thought you were here to enjoy, not to criticise."
"I was just…testing a theory."
Lewis ignored the sergeant for a moment and instead sat back in his pew, thinking, waiting for the concert to begin.


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Fibroblast growth factors 7 and 10 are expressed in the human embryonic pancreatic mesenchyme and promote the proliferation of embryonic pancreatic epithelial cells
- First Online:
- Received:
- Accepted:
DOI: 10.1007/s00125-004-1638-6
- Cite this article as:
- Ye, F., Duvillié, B. & Scharfmann, R. Diabetologia (2005) 48: 277. doi:10.1007/s00125-004-1638-6
- Citations
- 647 Downloads
The fibroblast growth factor (FGF) family consists of 22 members. In rodents, several FGFs are expressed in the pancreas, where they participate in epithelial–mesenchymal interactions. Our objective was to describe the pattern of expression of FGFs in the human embryonic pancreas and to analyse their effect on pancreas development.
The expression of FGFs was analysed by RT-PCR. To investigate the cell types expressing FGF7 and FGF10, we separated epithelial from mesenchymal cells using immunomagnetic beads linked to E-cadherin antibodies and performed real-time PCR. The effect of FGF7 and FGF10 on proliferation of human embryonic pancreatic epithelial cells was evaluated in vitro by measuring BrdU incorporation.
We found that different FGFs are expressed in the human embryonic pancreas, and we focused on FGF7 and FGF10. We defined a new approach to separating epithelial cells (containing the pancreatic progenitor cells) from mesenchymal cells. This allowed us to demonstrate that human embryonic pancreatic mesenchymal cells express both FGF7 and FGF10. We next demonstrated that FGF7 and FGF10 were able to induce the proliferation of the epithelial cells in vitro.
These findings indicate that it is now possible to efficiently separate human embryonic pancreatic epithelial from mesenchymal cells, an important step to characterize and expand progenitor cells. This method allowed us to demonstrate that human embryonic pancreatic mesenchyme expresses FGF7 and FGF10 that act on epithelial cells to activate their proliferation. Such growth factors could thus be used to expand human embryonic pancreatic epithelial cells.
KeywordsDevelopment Embryonic FGF Human Pancreas
- BrdU
early growth response 1
fibroblast growth factor
- FGFR2b
fibroblast growth factor receptor 2b
- Pdx1
pancreatic and duodenal homeobox factor 1
reverse transcriptase polymerase chain reaction
Type 1 diabetes is caused by an autoimmune destruction of pancreatic beta cells resulting in insulin deficiency and consequent hyperglycaemia. Recent data have shown that the replacement of damaged beta cells by the transplantation of islets from donors could be used to provide a continued insulin reserve and a long-term glycaemic control [1]. The major obstacle remains the insufficient supply of cells. Thus, alternative sources of beta cells have to be found.
Recently, the potential of different human cell types and tissues to differentiate into beta cells has been evaluated. For example, human embryonic pancreata at an early stage of development were used [2]. In this model, it was shown that when human embryonic pancreata at 6–9 weeks of development that contain very rare insulin-containing cells were grafted under the kidney capsule of NOD/scid mice, the tissue grew, increasing in weight 200 times within 6 months, and the endocrine cells differentiated.
While data related to the control of pancreas development in rodents accumulate, little is known about the factors that control the proliferation and the differentiation of the precursors in the human embryonic pancreas. In rodents, it is now established that pancreas development is controlled by signals derived from different tissues that contact the endodermal regions. In the case of signals derived from the pancreatic mesenchyme, it has been shown that ligands of receptor tyrosine kinases are implicated in the control of pancreatic epithelial cell proliferation and differentiation. This is for example the case for members of the fibroblast growth factor (FGF) family. Specific ligands for fibroblast growth factor receptor 2b (FGFR2b), 47 and FGF10, are expressed in the pancreatic mesenchyme [3], and data based on loss or gain of function experiments indicate that both FGF7 and FGF10 are implicated in the control of pancreas development [3, 4, 5, 6].
In the present study, we have examined the expression of FGF7 and FGF10 in human embryonic pancreata at 6–9 weeks of gestation. We next designed a new experimental approach based on the separation of epithelial from mesenchymal cells and showed that in human embryonic pancreas, FGF7 and FGF10 are expressed in mesenchymal cells. Finally, we examined the role of FGF7 and FGF10 and demonstrated that both factors activate the proliferation of embryonic pancreatic epithelial cells.
Materials and methods
Human tissues
Human pancreata were extracted from embryonic tissue fragments obtained immediately after voluntary abortions performed between 6 and 9 weeks of development, in compliance with the current French legislation.
forward: 5′-CAGGTCCTGGCATCTTGTCC-3′
reverse: 5′-TTGCTGGTCTTGCCATTCCT-3′
forward: 5′- AGTGGGCACAGATGGTGTGA-3′
reverse: 5′- TAGGTGGAGTCCCAGGCGTA-3′
forward: 5′- CCTCACCTGTGAAGTGGATGC-3′
reverse: 5′- CAACGGCAAAGTTCTCTTCCA-3′
forward: 5′-ATCAGGACAGTGGCAGTTGGA-3′
reverse: 5′-AACATTTCCCCTCCGTTGTGT-3′
forward: 5′-CACATTGTGCCTCAGCCTTTC-3′
reverse: 5′-AGGTGATTGTAGCTCCGCACA-3′
forward: 5′-ATCATATGCCTGACCCCTTGC-3′
reverse: 5′-TTTCCCCCAAGTGAGGACCTA-3′
Selection of pancreatic epithelial cells from mesenchymal cells and SYBR Green real-time PCR
An immunomagnetic separation system (Dynabeads, Dynal) was used to separate epithelial from mesenchymal cells. Human embryonic pancreatic tissue was digested with 250 U/ml of Collagenase IV (Worthington), and the cells were mechanically dispersed through 18-, 23-, and 25-gauge needles. Cells were next incubated with anti-E-cadherin antibody raised in rats (a gift from Dr Kemler) and incubated with Dynabeads M-450 sheep anti-rat IgG (Dynal). Dynabead-bound cells were collected by Dynal magnetic particle concentrator (Dynal). Total RNAs from cells bound or unbound to beads were extracted for real-time PCR analysis and processed using the SYBR Green PCR Core Reagent Kit (Applied Biosystems) according to the manufacturer's instructions. Each sample was amplified in duplicate.
FGF treatment
Human pancreatic rudiments were cultured on Millipore filter inserts in 12-mm tissue culture plates in RPMI 1640 medium, and treated with 50 ng/ml of human recombinant FGF7 or FGF10 (both from R&D Systems), or PBS/BSA as control, for 1 h without serum (for EGR1 expression experiment ) or for 24 h with 1% serum (for cell proliferation experiment). During the last hour, 10 μmol/l bromodeoxyuridine (BrdU, Sigma) was added.
Paraffin-embedded, 4-μm-thick sections were processed for immunohistochemistry with antibodies directed against BrdU, pan-cytokeratin, vimentin, E-cadherin, and Pdx1 as described in [8]. The fluorescent secondary antibodies were Texas red anti-mouse, FITC anti-rat, and FITC anti-rabbit antibodies.
Expression of FGF7 and FGF10 in pancreatic mesenchyme
Effect of FGF7 and FGF10 on the proliferation of embryonic pancreatic epithelial cells
In human embryonic pancreas, the inability to separate the pancreatic epithelium from the mesenchyme has represented a technical limitation to studying epithelial–mesenchymal interactions. Kobayashi et al. [9] recently defined an approach to solving this problem in the rodent pancreas at late stages of development, by using Dolichos biflorus agglutinin (DBA) as a specific marker of epithelial cells, and the Dynabead system. Here we used another epithelial marker, E-cadherin, and magnetic beads, to separate human epithelial from mesenchymal cells. Our data indicate that human embryonic pancreatic fractions enriched or poor in E-cadherin–expressing cells can be obtained. Such cell populations will be useful in the future to compare the transcriptome of these two fractions. Here, we used this approach combined with real time PCR as an alternative to in situ hybridization to define whether FGF7/10 was expressed by epithelial or mesenchymal cells. Using the approach described above, we demonstrated that FGF7 and FGF10 are expressed by mesenchymal cells, as in rodents. The next step was to define whether human embryonic pancreatic cells were sensitive to FGF7/10. Another group has recently shown that FGF7 treatment activated beta cell development from human fetal pancreatic cell preparations grafted to athymic rats. No effect of FGF7 was seen in vitro, suggesting that the growth effect of FGF7 was indirect [10]. Here, we show that FGF7 and FGF10 also have a direct effect on embryonic pancreatic cells. This was demonstrated by their capacity to rapidly induce the expression of EGR1. Moreover, we were able to show that FGF7 and FGF10 specifically activated epithelial cell proliferation. FGF7 and FGF10 could thus be used to expand human embryonic pancreatic epithelial cells that could potentially be useful for therapeutic approaches.
In conclusion, we have used a new method of separation of epithelium and mesenchyme from human embryonic pancreas, which allowed us to demonstrate that FGF7 and FGF10 were expressed by mesenchymal cells. Next, we provide evidence that FGF7 and FGF10 are capable of inducing the proliferation of the pancreatic epithelium in a direct fashion, thereby amplifying the pool of precursor cells. Our discovery of this direct mitogenic effect of FGF7 and FGF10 provides a novel approach to enhancing the quantity of pancreatic progenitor cells that represent a potential source of beta cells.
We would like to thank Dr Kemler for antibodies. We are indebted to the medical staff in the department of gynaecological surgery at the hospital R. Debré (Pr Blot and Pr Oury). This work was supported by the Juvenile Diabetes Research Foundation (JDRF Center for beta cell therapy in Europe), the Association française des Diabetiques (AFD), and the Fondation pour la RechercheMédicale.


text: Beautiful 3 bedroom, 2 1/2 bath twin in thepopular Timberidge. One of the more private, larger lots in the subdivision. Tree Lined lot! Step inside this freshly painted home with neutral tones, New Flooring throughout. Great floor plan. Slider doors in the Living Room lead to a great deck. Below you will find a finished walk out basement w/ sliders to a patio. This home is a must see! Schedule your showing today!


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We had an hour or so to spare during our stopover in Delta Junction. We had read about the roadhouse so we called by to take a look and are so glad we did. It is an original...
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We had an hour or so to spare during our stopover in Delta Junction. We had read about the roadhouse so we called by to take a look and are so glad we did. It is an original roadhouse from the stagecoach days (albeit moved a couple of times) and gives an excellent view of travelling life in days gone...
This is a free attraction which is well worth a visit, if it is on your route (not special enough for a specific trip out as it is so far off the beaten track). Good point to break your journey North (or South for that matter) between Tok and Fairbanks.
I spent a couple of hours happily immersed in the recent past in the log cabin that has been transported to its present position in Delta Junction. The personal letters and artefacts really brought home to me the life of the pioneers in Alaska in a way that isn't possible just by reading about them. The place was set out...
Great place to stop and get a feel for what it was like years ago in Alaska. Nice photos and displays that represent this history of the area.
After visiting the friendly staff at the Visitor's centre walk across the road to visit this historic cabin, well worth it. There is a farmers market here on a Saturday morning.
A good museum showcasing the roadhouse system and lifestyle of the late 1880's-early 1900's. It is free!
We were lucky enough to be there when no one else was and the gentleman gave us our own private tour. He was very knowledgeable about the Sullivans and history of Alaska. Definitely worth the stop and check out the crystallized egg tin - who knew they had powdered eggs back in the 1800's!
This authentic roadhouse had a wonderful gentleman who was full of stories and history. We peppered him with questions and spent a most enjoyable hour learning about the roadhouse history so important in Alaska's past. Worth the stop at Delta Junction
This is a treasure tucked away in Delta Junction. A wonderful museum that was an actual roadhouse along the Valdez Trail. The community has brought it to life with authentic stories and items of the period, knowledgable local folk and quaint events that are charming. A great piece of significant Ak history, and it's FREE!
The cabin is amazing. There's a lot of history inside and a lot of the original pieces to look at. What's really cool, so make sure you check it out, is that they have the story from when the United States Army moved the cabin to its current location from its former location just by helicopters and a lot of...
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Improve measured latency with Intel® Ethernet networks by knowing what latency is, why it's important, and how to measure and improve. (v.1.2, Jun. 2012)
Intel sales engineers offer advice and support to maximize your design. Whether you are looking for design advice or help finding the right Intel partner, we can help.


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1. Re: What's fixed (or not) in v1.4.3laurieb52 Jun 29, 2012 1:22 AM (in response to DeanGibson)With the update, paragraph/punctuation markers and random numbers are showing up in the book descriptions under "view details" on both the "shop" and "library" sections, making it difficult to read the blurbs. I'm seeing this on about 80 per cent of the books I've checked.
2. Re: What's fixed (or not) in v1.4.3petesnook Jun 29, 2012 7:31 PM (in response to laurieb52)
Good catch. It's also happening to apps and magazines. But my hit rate is closer to about 40 percent on books and only occasionally on apps and mags.
3. Re: What's fixed (or not) in v1.4.3Schwa Jun 29, 2012 10:09 PM (in response to DeanGibson)
Before when clicking BUY on a Harry Potter listing it would direct you to open the browser and visit Pottermore yourself. Now the SHOP actually opens the appropriate Pottermore page in the browser for you when you click BUY.
4. Re: What's fixed (or not) in v1.4.3DeanGibson Jun 29, 2012 10:57 PM (in response to DeanGibson)
Newly broken:
- Once an app is downloaded, the download icon at the bottom keeps flashing until reboot. I don't know if this is a rooted-specific problem.
5. Re: What's fixed (or not) in v1.4.3flyingtoastr Jun 29, 2012 11:06 PM (in response to DeanGibson)
DeanGibson wrote:
Newly broken:
- Once an app is downloaded, the download icon at the bottom keeps flashing until reboot. I don't know if this is a rooted-specific problem.
Hm, not happening with my stock unit.
6. Re: What's fixed (or not) in v1.4.3junonia-shell Jul 1, 2012 11:34 AM (in response to DeanGibson)I second what laurieb52 said. My page turns are all messed up too. I do not use that animate page turns and have to keep going into the reader settings and check and uncheck the animate page turns. It lasts while I'm reading the book, but once I go to do something else like surf the internet or use an app, it goes back to animating the page turns. Both my tablet and NC have updated to 1.43 and both have the same problem.
7. Re: What's fixed (or not) in v1.4.3Reisnice Jul 3, 2012 8:58 PM (in response to DeanGibson)Does anybody else find it amusing that BN - a BOOK company - puts out a reader 'update' with such an obvious and easy to find bug in it? Granted, there are quite a few places to test changes in, but it sounds to me like nobody actually USED the applications before they were released. Since there are no advertised release dates, the only timeline was management imposed, and could have slipped a couple weeks to get things right. Or maybe I'm just more sensitive to these things because I do them for a living...
8. Re: What's fixed (or not) in v1.4.3Reisnice Jul 3, 2012 9:08 PM (in response to DeanGibson)And am I just expecting too much, or should there be more real enhancements in the time there was between 1.4.2 and 1.4.3? I realize that BN isn't a software company, but if they' re outsourcing development, they need to be looking for a new contractor. Of course if Microsoft is pushing them to Windows 8 now, I guess we're lucky to get anything at all in Android-land.
9. Re: What's fixed (or not) in v1.4.3KittyTea Jul 5, 2012 9:46 AM (in response to DeanGibson)My Living Language Essentials Spanish 1 now works - before the update it would not download. Thanks BN.
10. Re: What's fixed (or not) in v1.4.3lopaka47 Jul 15, 2012 1:57 PM (in response to KittyTea)
I still haven't received the update, wi-fi is only turned on long enough to dl books and then I shut it off again to conserve the battery. And since my Tablet apparently isn't on wi-fi long enough to get itself updated, I honestly don't know whether I should be feeling happy or disappointed right now.
11. Re: What's fixed (or not) in v1.4.3Irishelf Jul 15, 2012 5:00 PM (in response to lopaka47)Unless you're into comics, the update is useless.
12. Re: What's fixed (or not) in v1.4.3OHCholla Jul 20, 2012 11:04 AM (in response to DeanGibson)
My NT just got the update a couple days ago. Not sure whether this is a fix or a bug, but in certain apps the screen no longer times out. Sometimes it's convenient but other times I'm afraid that it may be too big a drain on the battery if I walk away with a PDF open and the Nook does not shut itself off.
13. Re: What's fixed (or not) in v1.4.3Reisnice Jul 26, 2012 6:59 PM (in response to DeanGibson)I just ran into something else apparently fixed, or at least improved, in 1.4.3. With the two previous releases, my NT would detect the public wifi router in the lobby of my office building, but never connect. Now, it still hangs on 'getting IP address', rejects the connection, but then retries and immediately connects. Weird, but much better, since we aren't allowed to get on public email systems from company PCs, and can't use wifi in the office. Saves lugging my laptop in when I expect an important email.


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By: William Larsen – Civilians News – "News For All Views" – November 2015 –
To whom it may concern, at The Board of Education,
I feel cheated, used and degraded, by the education I received from the American Board of Education.
How egocentric are we as a nation….. to focus strictly upon our own history? Furthermore, how mundane are curriculum's that don't properly divulge the history of our land, before the European invasion of 1492…..?
20 million Native Americans occupied this land before 1492. Yet, even during my college history courses, very little was ever spoken about this time period in American history. (A time period rich in conservation and becoming 1 with nature….)
With that in mind, it seems obvious as to why xenophobia is becoming such an issue in the United States today. Are we so cynical as a nation, so proud as a nation, that we cannot focus on; South American, Russian, Australian, African, Asian, Middle Eastern, Chinese, Japanese, Native American and European histories?
Einstein once said, history is the most important class in general education…….
Einstein also said, that he was discouraged by the mundane nature of public schools, as he applauded the importance of imagination……. Granted, Einstein was taught mostly from European institutions, his point rings true today…… How is it that an education system remains stagnant and mundane, decade after decade……? How is it that science and technology change every single year, yet our students are still learning in the same monotonous fashion as they were 50 and 60 years ago? Are we so closed minded as a nation, as to think that we can't evolve the sheer process of learning itself?
I myself can attest, that after reaching graduate school, post college graduation, that I often couldn't even string together proper grammar, for some years after college. In many ways I still struggle with grammar today, due to my disdain for the monotony, which has all but destroyed America's public education system.
As an American student myself, only 5 years ago, not only was my education insufficient….. but the mundane and monotonous form of teaching that is so common in America today, almost turned me away from reading entirely.
It was not until I discovered philosophy, ON MY OWN, when I truly began to break the surface of what I was capable of as a student….. And even then, I didn't fully grasp the capability of my mind until I began searching for answers on my own, through science, physics and philosophy…… In hindsight my time in American public schools nearly ruined these subjects for me, as opposed to igniting the desire to explore the fields of science and philosophy. Furthermore, at no point in my public education was I ever inspired to truly grasp the wonder of my imagination.
The standard practice; memorization, memorization, and more memorization, taught me nothing. I learned almost nothing memorizing answers for teachers, who often times asked, that I simply repeat the views they themselves held. While I will admit, some of my public educators did in fact take the time to motivate me as a child, most did not. In fact most of my teachers growing up pushed me away from learning altogether, due to close minded and rigid styles of practice, administered by the US Board of Education.
For this reason, I can also attest first hand that CHEATING is becoming a crippling issue in American public schools today…. This is a practice, that I believe is an offset of outdated education techniques… Cheating in public schools is something I think has long been overlooked by the U.S. Board of Education!
I believe this is occurring, not because of technology…. but because of the rigid and close minded parameters of an education system which no longer rewards thinking or imagination, but simply focuses on memorization and fact checking!
It felt so cumbersome, to memorize and repeat, memorize and repeat, because today's American classroom is so mundane and monotonous!
Not only that, in high school, my school commenced far too early in the morning!
My school started at 7:15am……. Well, after waking up at 5:30am, waiting for the bus at 6am, arriving to school at 7am and missing breakfast due to time constraints…. I was half awake most days by the time 1st period rolled around…. How are we to spark the minds of students, as adults, when teenagers in high school can barely stay awake!
These are but a few of the complaints I have, regarding American Public Education today. I hope this letter is carefully examined by the Board of Education. Furthermore, I hope this letter finds someone who genuinely CARES, because this is about the students who will one day lead this great country of ours….. At the root, the very core of our country, is the U.S. Board of Education…. and it would seemingly be unforgivable to corrode another generation, the way my generation was corroded, through mundane and outdated public education today.
Thank you for your time.
-William Larsen
An Open Letter To The Board Of Education


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After twenty years of leading the travel blog revolution, we're sorry to announce that TravelPod is closing its doors, on June 19, 2017.
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4300 Sovran "Morning Sun" shows like new!
Incredibly attentive,knowledgeable and caring owner and it shows.
Realistically and seriously offered.
Low hours,Pod oil pump updated,air-box/hull drain updated,pulleys/idler arms updated,drive seals updated,sea strainer updated,cooling system-aftercoolers serviced,line cutters and a host of other items; see full specs section.Additional details available from the Central Agent.
Central Agent is personally familiar with the vessel which is displayed just steps from the Broker's office.Note photos!
Beautiful Awlgrip Hull;2014 Huckins Yacht- two coats and clear coat ,custom hard top,Bridge Air,Joy Stick controls,bow thruster,system upgrades as noted in "Full Specs" section.
IPS Drives allow for two full staterooms, each with it's own head.
Volvo D6 IPS 500 370 HP.
Many will prefer this engine model which provides good performance,fuel efficiency,without maximum horsepower increase on basically the same engine as seen with 'higher' HP ratings,and still delivers excellent performance- Cruise 23 Knots @ 3030 RPM.
Berthed inland Jacksonville,covered slip.
Convenient to see,by appointment.
Contact Central Agent Mike Webster directly
Cell 904-923-0033 firstname.lastname@example.com
Vessel is convenient to see at the Lambs Yacht Center "Floating Showroom",by prior appointment to assure service.
Striking lines and appearance.
Blue hull,fiberglass hardtop with integrated windshield.
Air conditioned bridge features lounge seating,table,wet bar.
Open cockpit with sunshade extension,fore and aft seating.Excellent engine room access via electric lift hatch.
Extended transom platform and transom trunk.Wide side decks provide solid footing.
Luxurious interior featuring two staterooms,each with their own separate head.Forward stateroom with queen berth on center.
Open salon with convertible settee to starboard and full service "L" shape galley to port.
Full size guest cabin aft with it's own privacy door-not curtains.
Solid surface counter tops,teak paneling and Tiara signature Teak & Holly flooring.
Entire vessel looks and feels near brand new-note photos.
Volvo IPS-A Drives updated to D features.Receipts avaiable.Original drives were replaced.Updated oil system,SST drive ring and springs.
Drives serviced,oil & filter change May 2016
Routine scheduled oil sample analysis reports
Routine trial run mid June 2016;wide open throttle-3530 RPM,34.3 MPH
Cruise 27 MPH @ 3030 RPM
Bow Thruster
Onan Generator 508 hours
Present owner renewed generator sound shield and installed digital gauges
220V/50 amp & 125V/30 amp shore power
Glendinning Cablemaster
Charles 100 amp battery charger
(5) batteries; 2 Odyssey AGM House,3 Optima AGM main engine & generator
Galvonic Isolator
(4) Zone marine reverse cycle air conditioning,including bridge
Racor fuel filters
Single fuel tank with Port & Starboard fuel fills for convenience
(4) Bilge pumps;2 in engine room,2 forward
Lube oil/filter change May 2016
See Mechanical section for Pod update details
High Water Alarm
Air Conditioning condensate drains routed out of bilge and to sump
Air conditioning discharge updated/new dedicated through hulls
Main engine raw water strainers upgraded
All nylon thru-hulls replaced with Bronze
Updated POD oil system,SST steering pivot.
Original Pods replaced under warranty- "A" pods upgraded to most "D" class- receipts available
POD line cutters
Updated main engines pulleys/idle arms updated
Generator sound shield renewed
Televisions replaced with new HD.Salon 2015,staterooms 2016
Dual screen Ray Marine E120 Radar,GPS
Simrad Auto Pilot
Depth Finder
Bose Stereo system for below decks;sub woofer,five speakers
Clarion Stereo system for topsides; amplifier,five speakers,custom fiberglass locations
All three TV's are new HD
Salon in 2015,staterooms in 2016
Painted hull;Blue Awl Grip with clear coat.
Huckins Yacht Corp. 2014
Bottom Paint May 2016
Cockpit curtains
Fresh & salt water wash down;cockpit
Anchor windlass,anchor,fresh water wash down at anchor locker
Cockpit shower;hot & cold
Remote spot light
3344 Lake Shore Blvd
Jacksonville, FL 32210
United States


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Posted by Evergo Concepts - VERIFIED SELLER VERIFIED19 Feb 4:26 pmIru/Victoria Island, Lagos
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Provides account services to customers by receiving deposits and loan payments; cashing checks; issuing savings withdrawals; recording night and mail deposits; selling cashier's checks, traveler's checks, and series e bonds; answering questions in person or on telephone; referring to other bank services.
Records transactions by logging cashier's checks, traveler's checks, and other special services; preparing currency transaction reports.
Cross-sells bank products by answering inquiries; informing customers of new services and product promotions; ascertaining customers' needs; directing customers to a branch representative.
Completes special requests by closing accounts; taking orders for checks; opening and closing Christmas and vacation clubs; exchanging foreign currencies; providing special statements, copies, and referrals; completing safe-deposit box procedures.
Minimum of OND,BSC,HND from any accredited university.
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Dragon Age: Origins - Warden's Keep
Some claim the fortress of Soldier's Peak is corrupted and overrun by demons. Others whisper of betrayal and the spirits of murdered Grey Wardens. Whatever the truth, Soldier's Peak is no place for the living. Relive the darkest hour of the Grey Wardens with all-new content that adds to the main Dragon Age: Origins campaign. This downloadable adventure reveals secrets hidden for generations, and includes unique achievements, unlockable character abilities, powerful items, and much more!
If you're stuck in Dragon Age: Origins - Warden's Keep, ask your fellow GameFAQs members for help.
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by John Papadopoulos
This is a no-nonsense guide to drug treatment in the intensive care unit. It covers the most commonly encountered conditions and is organized by system. Management of each condition is tersely outlined step-by-step in table format. The book also includes non-drug information that is essential to making informed, evidence-based pharmacotherapy decisions, such as risk scores, scales, and assessment tools.
The Second Edition has been revised to reflect the latest critical care practice guidelines and up-to-date drug and non-drug information.
Note: Only Diamond member can download this ebook. Learn more here!


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This Safety 1st set lets you monitor baby with certainty.
Customer with a shipping address in eligible NY Metro areascan choose
at checkout, to get their order delivered on the same business day.
Just place your order by 9AM and choose "Same-Day Delivery".Orders placed after 9AM or on a weekend/holiday will be delivered the next business day.


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We are offering for sale a men's ring in 10kt yellow gold. This men's ring is set with a rectangular cut tiger's eye quartz cameo (6.00cts), opaque with golden-brown striations. It depicts a Trojan-like warrior's head facing left ( the nose and helmet are chipped). The ring is hallmarked 10k; `S' and is a size 9 1/4. The ring was cast, handset and is in very good condition. This includes an insurance appraisal of $750.00. Free shipping in the USA.
Fine Art & Treasures from Around the World.
Free Shipping on Jewelry within the USA. Ask us about our 9 month lay away plan. Celebrating 55 years in business.


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This content will become publicly available on September 14, 2017
Loss-tolerant quantum secure positioning with weak laser sources
Quantum position verification (QPV) is the art of verifying the geographical location of an untrusted party. It has recently been shown that the widely studied Bennett & Brassard 1984 (BB84) QPV protocol is insecure after the 3 dB loss point assuming local operations and classical communication (LOCC) adversaries. Here in this paper, we propose a time-reversed entanglement swapping QPV protocol (based on measurement-device-independent quantum cryptography) that is highly robust against quantum channel loss. First, assuming ideal qubit sources, we show that the protocol is secure against LOCC adversaries for any quantum channel loss, thereby overcoming the 3 dB loss limit. Then, we analyze the security of the protocol in a more practical setting involving weak laser sources and linear optics. Lastly, in this setting, we find that the security only degrades by an additive constant and the protocol is able to verify positions up to 47 dB channel loss.
- Authors:
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Computational Sciences and Engineering Division
- Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States). Research Lab. of Electronics
- Univ. of Tennessee, Knoxville, TN (United States). Dept. of Physics and Astronomy
- Southern Illinois Univ., Carbonadale, IL (United States)
- Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States). Computational Sciences and Engineering Division; Univ. of Tennessee, Knoxville, TN (United States). Dept. of Physics and Astronomy
- Publication Date:
- OSTI Identifier:
- 1325473
- Grant/Contract Number:
- Type:
- Accepted Manuscript
- Journal Name:
- Physical Review A
- Additional Journal Information:
- Journal Volume: 94; Journal Issue: 3; Journal ID: ISSN 2469-9926
- Publisher:
- American Physical Society (APS)
- Research Org:
- Oak Ridge National Laboratory (ORNL), Oak Ridge, TN (United States)
- Sponsoring Org:
- USDOE; U.S. Office of Naval Research (ONR); ORNL work for others; ORNL Program Development
- Country of Publication:
- United States
- Language:
- English
- Subject: