text:
Barry Melrose on D&C: Thomas 'only guy to talk about' for Bruins
|05.24.11 at 10:23 am ET
ESPN NHL analyst Barry Melrose called in to the Dennis & Callahan show Tuesday morning and predictably talked about the play of Bruins goalie Tim Thomas, who allowed just one goal on 34 shots in Boston's 3-1 win over Tampa Bay Monday night in Game 5 of the Eastern Conference finals and made perhaps the best save of the playoffs in the third period on a shot from Tampa Bay's Steve Downie. (To hear the entire interview, click over to the Dennis & Callahan audio on demand page.)
"Last night, he was the only guy to talk about," Melrose said. "The Bruins basically took the first half of the game off and left Timmy Thomas out to fend for himself. The guy was great. He was fantastic. He made that game-saving save later in the game. But right off the start, he was very solid. You could tell he was on his game. He was very aggressive. He was outside the crease. And that's how you tell if Timmy's ready to play or not. If he's making saves inside the paint, it's going to be a long night. If he's out challenging and outside the paint and very aggressive, it's going to be a good night for Timmy Thomas. Last night, he was really on his game."
Melrose was also willing to discuss the Lightning situation between the pipes. Tampa Bay coach Guy Boucher gave Mike Smith the start in net instead of Dwayne Roloson, who had started the previous four games in the conference finals. Despite Tampa Bay's loss on Monday, Melrose said he would stick with Smith going forward.
"I think Mike Smith. I think number one it's hard to go back to Roloson," Melrose said. "You have a 41-year-old goaltender. You pull him twice. You bench him and then say, 'Hey man, we made a mistake. We want you back.' So I think it's Mike Smith's series now, win or lose. And Mike Smith played well, those two goals he gave were basically unstoppable. The guy handles the puck well. That created a lot of problems for Boston. If Boston falls asleep, Mike Smith will make that long pas and create a breakaway at the other end. So that gives Boston another thing to worry about when they're looking at their gameplan." Read the rest of this entry »
Claude Julien says Johnny Boychuk is 'fine'
|05.24.11 at 3:53 am ET
The Bruins got a bit of a scare in the third period of their 3-1 vicctory in Game 5 of the Eastern Conference finals when Lightning forward Steve Downie took a run at B's defenseman Johnny Boychuk and sent Boychuk down the tunnel and out of the game. Downie went off for boarding, and though Boychuk didn't take another shift, the encouraging news was that he made his way back to the bench for the end of the contest. Coach Claude Julien said he did not see the hit, but that the defenseman is OK.
"Johnny is fine," Julien said. "I haven't had an opportunity to look at it. I haven't watched the video yet. I know some people have, but from what I hear it's not a great hit. I'll maybe save my comments more for after I see it."
Boychuk logged 16:09 of ice time before leaving after the play, which occured at 10:54 of the third.
Video: Bruins react to Game 5 win
|05.24.11 at 1:27 am ET
Claude Julien: 'We can't be tight' if we want to reach Stanley Cup finals
|05.24.11 at 1:26 am ET
Claude Julien is on the verge of taking his Bruins to a place no one has in 21 years. It's a place he won't mention by name by it starts with "Stanley" and ends with "Cup finals".
And after Monday's 3-1 win in Game 5 of the Eastern finals, he's more than prepared for all the questions he'll be hearing about it over the next two days.
"Well it's going to take, and you've heard it before, it's almost a cliché, it's going to take our best game. When a team's got its back against a wall, it comes out with the best of efforts and this is where we have to make sure that next game, as I mentioned here earlier, we can't be tight," Julien said. "We've got to out there and play with a purpose and be ready to go out there and play hard.
"Maybe put them on their heels and maybe get them to play tight. But this is the position you want to be in obviously, up in the series. We've got two games here to win one. Our goal right now is not to play Game 7. And I know their goal is to create a Game 7. So, there's a difference between the two teams."
Julien doesn't want to see his team feel the pressure in Game 6 the way they did in the first period Monday night.
"I just think we need to understand we've got the lead in this series. And we've got to go out there and play without playing on our heels. When you've got the lead like that you should go out and play on your toes, not your heels, and if you play well enough, maybe you put the other team on their heels. I didn't say we are groining to put them on their heels, I said the goal is to play well and try to play as well as you can. And they've got their backs against the wall, so this is our opportunity here to come up with our best effort of the series." Read the rest of this entry »
Guy Boucher thinks Tim Thomas is a miracle-worker
|05.24.11 at 12:45 am ET
All series long, Lightning coach Guy Boucher has been complimentary of the Bruins, especially Tim Thomas. After Monday's Game 5, in which Thomas stopped 33 of the 34 shots he faced, Boucher tried to explain just how difficult it is to win a game against Thomas when he's playing his best.
'It's extremely hard to play in this building, and to get 30-something shots and hold your opponent to 20, you should take that,' Boucher said. 'But that's not enough against this goaltender. You need more. You need miracles. He's making miracles. We have to come up with miracles.'
The Lightning ended up outshooting the Bruins 34-20 in Game 5, including 14-4 in the first period. When asked if it was frustrating to dominate shots like that and not win the game, Boucher had an interesting response.
'We're not frustrated. We're expecting that,' he said. 'He's done it all year. He's done it in the playoffs. If you don't expect that, it's because you got the wrong expectations.'
Boucher said the only thing his team can do is throw even more shots at Thomas.
'Good's not good enough if you want to beat that goaltender,' he said. 'At one point the shots were 30-12 or something like that, so I guess we're going to need 55. There's no two ways about it.'
Of course, Thomas might not be quite as invincible as Boucher makes him out to be. After all, the Lightning have scored four or more goals on him three times in this series, and it didn't take 55 shots to do it.
The Lightning players said the biggest difference between those games and nights like Game 3 (a 31-save shutout for Thomas) and Game 5 is the quality of their shots.
'I think he saw the puck pretty good tonight,' Ryan Malone said. 'It looked like it was point shots most of the time. He's a world-class goalie. If he sees it, he's going to stop it. It's our job to make him not see it.'
Perhaps that would help create some of the 'miracles' Boucher is looking for.
Tim Thomas: Bolts first goal actually made me 'relax'
|05.24.11 at 12:43 am ET
It was the most sensational save of a sensational season for Tim Thomas.
With 10:40 left in the third period and the Bruins holding a 2-1 lead, an Eric Brewer missed shot off the boards from the point meant Steve Downie had an open net for a game-tying tap-in. Then Thomas and his stick appeared at the very last possible moment. Thanks to that brilliant save and 32 others, the Bruins won, 3-1, and are on the doorstep of their first Stanley Cup finals appearance since 1990.
And to think Thomas actually credits the spectacular save and phenomenal game – in part – to the only goal he allowed on the night. The score 69 seconds into the first by Simon Gagne – of course – might have made the crowd and Bruins fans everywhere really nervous. It had the opposite effect on Thomas.
"Well, two things happen," Thomas explained. "One, the thought crosses your mind that, oh, I got to bear down even if it's another two-on-one I got to find a way to make the save because we can't afford to get down 2-0. The teams are too tight and the games are too tight for that to happen, so that thought is in there.
"The second thing that happens is actually in a funny way to start to relax a little bit and I don't know how it works but it kind of works that way for me. I don't want to let in an early goal, obviously, but I've had experience with it in the past and for some reason, sometimes it can relax me and that's kind of the effect it had tonight. It was just kind of like I'm going to have to work hard and do the best I can to not let them get any further way and to give us a chance to win." Read the rest of this entry »
Bruins overcome rough start, take Game 5
|05.23.11 at 10:49 pm ET
By DJ Bean and Scott McLaughlin
The Bruins pulled the opposite of the first-period-only effort that cost them Game 4, and on Monday night at the TD Garden, they overcame a terrifying first 20 minutes in Game 5 to beat the Lightning, 3-1, and come within a win of reaching the Stanley Cup Finals.
With Tampa Bay leading 1-0 after dominating the first period and seeing Simon Gagne score his latest against the B's, the Bruins got second-period goals from Nathan Horton and Brad Marchand to give Boston a 2-1 lead that they would hold until Rich Peverley made the final 3-1 on an empty-netter.
The Bruins didn't get many shots on Tampa goalie Mike Smith (only four in the first period), but the two they did get past him proved to be enough. Boston's 20 shots on goal stands as their lowest total this postseason.
Tim Thomas made 33 saves on the night, turning in a sensational performance that undoubtedly stands among his best this postseason. On a rather fascinating note, the team that has scored the first goal this series has now gone 2-3.
A late hit in from Steve Downie in the third period forced Johnny Boychuk down the tunnel, and he did not play in the final 10 minutes of the game.
The Bruins will have the opportunity to close out the series Wednesday night in Game 6 at St. Pete Times Forum.
– On the night, Thomas was superb. Downie was the biggest victim of Thomas' play, as the Bruins netminder robbed him on multiple occasions. Thomas stopped Downie point-blank on a bang-bang play in the second, but made one of the best saves of his historic season in laying out to get his stick on what looked like a sure-fire game-tying goal. The Garden absolutely erupted when Thomas was shown on the big screen at the next stoppage.
– Brad Marchand finally showed up on the sheet, and not just for his dive in the second period. The 23-year-old rookie didn't let Martin St. Louis take him out of the play him as he raced to the net to put bang home a beautiful pass from Patrice Bergeron down low. It was Marchand's first point of the series, as he followed a six-point second round with goose-eggs and only five shots on goal in the first four games against the Lightning. Marchand's overall performance continues to leave more to be desired, but he had flashes — such as a hard-nosed shift about five minutes into the third period — that suggest the B's could be closer to seeing the Marchand they got to know and love over the regular season and throughout the first two rounds.
– The Bruins were beyond lucky to somehow end up winning the game, and an individual instance in which they lucked out was when Thomas barely got a piece of the puck on a great opportunity by Blair Jones early in the third. The contact Thomas could make with the puck was enough to it off send it off the post on its way away from harm. Jones was just as sure as any that he would score on the play, as he was celebrating as the puck took its new direction.
– The Bruins came out looking like a team totally unaware it was in Game 5 of the conference finals. From physicality to decision-making, it was an awful first period and one that should have seen a larger Lightning lead than 1-0. The Bruins had only four shots on Smith in the first period, and aside from one strong shift late in the first by the David Krejci line, there was little to no engagement from Boston's forwards.
– Horton ultimately redeemed himself by scoring the tying goal in the second, but his two penalties before that were, for lack of a better word, dumb. In the final minute of the first, he laid a hit on Nate Thompson in the neutral zone despite the fact that the puck was already a good 10 feet behind him. Less than a minute after leaving the box, Horton went right back in when he slashed Hedman's stick out of his hands after missing a big hit. The Bruins want and need Horton to play with an edge, but his two penalties Monday night clearly crossed the line.
– Not a good night for Tyler Seguin. He looked lost in all zones in the first period and took an obvious tripping penalty with the B's lifeless and trailing 6:45 into the first. The rookie was taken off the third line late in the period by Claude Julien and was replaced on the wing by Peverley. He would play more in the second period, but had a turnover on a blind pass in the offensive zone that led to a Lightning rush that was saved by Andrew Ference.
– The power play was possibly the worst it's been all playoffs, as impossible as that might sound. The Bruins registered zero (yes, zero) shots on goal on their first three power plays. Bad entries and bad passes were once again the name of the game for Boston's man advantage. They struggled to get the puck in deep and gain possession, and when they did, they struggled to put passes on the tape, resulting in a number of easy clears for the Lightning. It's one thing to not score on the power play; it's another to not even get a shot. The one good sign on the power play was that Julien finally used Zdeno Chara as a net-front presence on the team's last power play. They even got a shot on the fourth power play.


text:
Him: A Rough NightMature
Nighthawk stood there in the middle of the street, fists held up like a boxer. I laughed, I wasn't looking for a fist fight. I fired off one shot from my gun towards her. It caught her with an electric shock, which I could see arcing from her body. She rattled like a maraca, but remained on her feet. I had to hand it to the girl, she was pretty resilient.
With a shout of defiance, she flew towards me, her arm outstretched in a punch. Grinning, I dropped the gun, and braced for impact. My suit's armor took the brunt of the damage, but we both flew back several yards, towards the police cars behind me. I landed back first on the asphalt, and aimed a return punch at her ribs. We fought, back and forth, without any real coherent words for a few minutes, and then fell apart. I was breathing hard, but she wasn't. Quickly, I controlled my breathing.
"You'll never stop my master plan. Someday, all these people will see you for what you really--" I was interrupted in my monologue by another blow, this time a kick, to my stomach. The air was pushed back out of my lungs, and I narrowly avoided sinking my knees while catching my breath. She grabbed my collar and lifted me up several stories in the air.
"Or maybe they'll just see who you are." She said icily, her eyes behind the mask cold bits of steel. She threw me onto the roof of a nearby building, and flew away. I lay there in the gravel for a few minutes, bruised and battered, but satisfied.
I let the police clean up the robot. I would build another one, a better one, next time. I found my civilian clothes, tucked behind a dumpster near a pizza place a few blocks away from my lab, and changed quickly into a black leather jacket and jeans. My helmet turned black at the push of a button and I strode out of the alleyway with my cape and suit in a backpack.
"Hey, it's Jake!" The owner of the pizza place shouted in greeting. I waved a hand at him, but didn't respond, revving up my motorcycle, and only real source of transportation. I headed back to my apartment. I lived in a high rise not too far from Sky University, where I was attending classes. It was a pretty nice place. Two bedroom, two bathroom setup. My last roommate had ended up moving away, for personal reasons, and I had it to myself. For now. The landlord had already put out a request for another tenant in my name.
"Jake! That advertisement will go out tomorrow," The landlord said as I entered the building. "I expect you to fill that empty room by the end of the week."
"Yeah, yeah. It'll get done," I said, trying to dodge him and get to the elevator.
"I mean it, Katran. You've had all summer on your own in that apartment. It says on your lease, that two people must be staying in that apartment. It's get a roommate, or move out."
"I get it, I get it. I'll get a roommate, I promise." I said, finally managing to get into the elevator and close the door on him.
I entered my apartment, and then the soreness hit me. You try being thrown into streets and onto roofs. Armor only did so much. Fortunately, I had no head injuries. Limping like an old man, I removed my shirt lay down on my bed without bothering about sleeping in my jeans. I was out like a light.
The next morning, my soreness had turned to stiffness, and I could barely manage to get out of bed, but school was due to start on Monday, and I had to get a jump on my next plan of attack against Nighthawk or I would never have time to execute it.
I limped to the kitchen, and managed to pour myself a bow of cereal when there was a knock at my door. Groaning, I went and opened it, to see a pretty girl with long brown hair and big brown eyes standing outside, her hand poised to knock again. There was a backpack over her shoulder, and a newspaper in her hand.
"Hi," she said cheerfully.
"Hi," I replied, looking her up and down.
"Um, is this apartment 3B?" She asked, her eyes tracing over my bare chest, and the pattern of bruises there.
"Uh, yeah," I said, reaching for a shirt and pulling it on. "Can I help you?" She held up the newspaper, showing the ad my landlord had sent out. I glanced at it.
"I saw your ad in the paper," she said. "And I need a place to live. Can I come in?"
"Oh, yeah." I opened the door wider and stepped aside. She came in, taking in the furniture and spartan decor.
"Nice... place," she said.
"Thanks. Let's get down to business," I said, closing the door again. "Do you have any pets?"
"No pets."
"Any boyfriend, friends coming over? For security reasons."
"It's just me," she answered, her eyes wide and innocent.
"Alright. What's your name?"
"Maria Hudson."
"Jacob Katran." We shook hands. Despite her light frame, she had a firm grip. "I have two rules. Don't bring anyone home, and don't bother me while I'm working. If you are out past midnight, seriously consider staying someplace else before coming back here. Do you understand?"
"Yes, you won't have to worry--"
"Then I suppose you can stay in my spare room. The landlord will have a key for you, your half of the rent is due on the first." I swear she practically hugged me, before dashing out the door again.
"Thank you, thank you, thank you!" She babbled. "I'll go get my stuff." Then she was gone in a blur of long brown hair.
I sat down on the couch, still staring at the door as it swung slowly shut.
"Jake, what have you gotten yourself into?" I asked out loud, but my reflection in the coffee table didn't reply.

subset: commoncrawl


text:
Sorry you're having a bad experience. Tell us how we can improve...
Not ?
We're excited to introduce you to our brand new site! All the great deals from DealChicken, plus more than 50,000 free coupons from 20,000 more local merchants!
We're excited to introduce you to your new local savings and gift certificate center!We've added offers and listings for over 20,000 local merchants and grown by 109 cities.
What are we asking? Linking accounts means we will allow your Facebook account to access your existing Local Flavor account.
For security purposes, we require you to simply log in with your email and password to confirm this is the account we should link to Facebook.
Warning: If you click NO, but you already have an existing account (with a different email address, for example), you will end up with two different accounts.
Or you can create a brand new Local Flavor account using the info from your Facebook.
Oops, We need your Phone
Best Tile is truly passionate about tile and stone. As experts in the industry, and one of the largest importers of tile and stone products, Best Tile is proud to offer an extensive selection of ceramic, porcelain, natural stone, metal, glass, mosaics, marble, floor, accent tiles and so much more. Best Tile provides inspiration for any budget, and will help create a look that is uniquely yours.
When new offers are available from this business.


text:
Connecting Families to Senior Living
Talk to a local advisor for FREE
Talk to a local Advisor about this community
Contact this community at:
(866) 333-2174
16940 Georgia Avenue
Facility License: 15AL0500-A
Caretypes Provided: Alzheimer's Memory Care
Pricing is available for the following rooms:
*Prices quoted are monthly rental charges and are provided by the communities themselves. Actual prices may differ due to one-time fees, timing and care services required. Speak with your Senior Living Advisor to learn more.
Our apologies. Pricing is currently unavailable for this particular community.
Olney Assisted Living is a memory care specific community for individuals with Alzheimer's disease and other types of dementia. Compassionate care is provided in an environment designed specifically for those with memory loss. Each community trait and building feature has been selected to foster independence and freedom. This includes cozy interior 'neighborhoods,' a central Town Center featuring a beauty/barber shop, and individual memory display cases outside of each resident's room to help with recognition. Daily life enrichment programming is provided with the goal of enhancing cognition, feelings of accomplishment, and quality of life. Licensed, on-site nursing care is provided 24 hours a day, seven days a week by a team of experienced professionals. Families seeking memory care for a loved one will feel right at home in this brand new community, which is filling quickly.
Schedule an appointment with an Advisor
out of 4 reviews
Olney Assisted Living
"I had a short window of time to find mom a senior care
facility and thanks to your diligence, follow up and
professionalism, you helped me immensely to find a
great facility for my mom."
Bill P., Found Assisted Living in Fallston, MD
"I've never heard my mom say how good she feels and how
loved she feels as she has with this new place. She is very happy
there and her health is great! She is eating great tasting
food, her sugar levels are in control and her legs are looking the
best I've ever seen them. I cannot thank you enough for all that
you did."
JoAnn C., Found Assisted Living in Baltimore, MD
The staff here is good and they work well with mom. At first there was problems, but they were prompt to get them handled. Mom likes the food and going to the dining hall to mingle. The communit... more...
Call Now (866) 333-2174
Get the latest tips, news, and advice on aging and caregiving.
A Place for Mom is the largest assisted living referral service. We are paid by our participating communities, therefore our service is offered at no charge to families.
Copyright ©2017 A Place for Mom, Inc. All rights reserved.


text:
Wakeboarding technology is better than ever and the major companies involved are pushing the limits year-after-year so that we can pop higher off the wake, ride rails, and cruise the cable park. ActiveWake.com carries all the wakeboarding gear you need to get out on the water and have fun. Shop the latest wakeboarding gear from Ronix, Liquid Force, Slingshot, and Hyperlite.
3 Item(s)
|3 Item(s)
Grid List
Liquid Force 2017 Melissa Wakeboard
Ronix 2016 Quarter 'Til Midnight
Regular Price: $439.99
Special Price: $328.99
Touch the sky or ride the rail with our best selling wake/park crossover women's boards. Want a smooth, fast glide on the water and a predictable snap off the wake? The always consistent take off of the Quarter 'til Midnight, with a longer flight in the air, and added pressure points on rails has made it popular with first time shredders all the way up to our pro team. It's time to see how far wakeboards have evolved with this new shape featuring speedwalls.Learn More
Slingshot 2017 Valley Wakeboard
• Makes pressing a piece of cake
• Loose snow-style feel on the water
• Upgraded park base can handle all obstacles
• Forgiving, user-friendly feel great for progression
2017 Valley: The Valley is a new female-specific park board designed for riders looking to take their rail riding skills to the next level. The extra soft flex pattern allows for big presses and helps riders experience the true feeling of locking in and holding a press. The flex also brings new excitement to the simple moves like carves and sprays. The Valley's wide profile and fast continuous rocker line allow the rider to cruise effortlessly through the park and put all their focus on mastering each and every obstacle. The Valley features the gorgeous signature artwork of Ms. Kim Kirch, the most influential artist in women's wakeboarding. Learn More
3 Item(s)
|3 Item(s)
Grid List


text:
SnowGlobe Studios
What does it take for a man to step into the cage? Herman Terrado discusses the challenges of being a professional MMA fighter.
SnowGlobe Studios
Directed by Roman Arriola
Director of Photography: Frederick Duarte
Produced by: Paul Von Petrzelka and Adriel de la Torre
Assistant Director: Thomas DiMaggio
Executive Producer: Randy Martinez
Camera: Frederick Duarte, Paul Von Petrzelka, Adriel de la Torre, and Thomas DiMaggio
Edited by Roman Arriola
Music by Altrice
Shot on Canon 5D and Red Scarlet


text:
Tiger JNP1500 Electric Rice Cooker and Food Steamer
Item No.: Tiger - JNP-1500
Ratings: (0 review).
Availability: Out of Stock
Ships from U.S Warehouse. Most customers receive within one week.
Price: $135.20
Note: Order placed before 12:30PM Pacific Standard Time will normally be processed in the same day.
Related Items
Tiger Jnp0720 4 C. Electric Rice Cooker
Sunpentown 10 Cups Stainless Steel Cooker & Steamer
Tiger JNP1800 10 Cup Electronic Rice Cooker/Food Steamer
Tiger JAZA10U 5.5 Cup America Rice Cooker/Steamer
Sanyo EC-503 3-Cup Rice Cooker and Vegetable Steamer
Toastess TRC18 20 Cup Jar Style Rice Cooker
Rice Dispenser (26lbs Capacity)
Black & Decker RC3406 6-Cup Rice Cooker
Tiger JNP0550 3 Cup Electronic Rice Cooker and Warmer
Sanyo ECJ-N55W 5.5-Cup 500-Watt 1-Touch Controlled Rice
- Tiger Electric Rice Cooker - Cooking fluffy, delicious rice is as
- Easy as pushing a button. The JNP-18U0, by Tiger of Japan, steams
- Up to 10 cups of rice to perfection, then keeps it warm until
- Saving time. Advanced cooking features such as surround heating for even cooking
- Thermal Read Switch to precisely control temprature and steam flow. Nonstick inner pan cleans easily and the cord retracts for storage.
- Measuring cup and rice ladle included.
- Heavy duty unit is built to last .
- Electronic control heating makes better rice.
- High quality double wall construction with locking top to seal in flavor.
- Special keep-warm heating elements (in the lid and in body) keep rice
- warm up to 12 hours without drying or burning the rice.
- Includes measuring cup, spatula, cooking and steamer pans - everything necessary to make tasty rice dishes and other foods.
- Water level marks on inner surface of ricecooking bowl insure the correct amount of water is added.
- Indicator lights show whether cooking or warming mode is in use.
- Non-stick PTFE coated rice cooking and steamer pans make clean-up easy.
- Built in carrying handle for safe and easy moving.
- Retractable power cord reduces counter top clutter and stays attached for storage.
- Removable non-stick rice cooker bowl.
- Removable inner lid.
- Detachable moisture collector.
- 180ml (approx. 6 oz.) rice measuring cup.
- Spatula/scoop.
- Scoop holder (attaches to side of cooker unit).
- 53 inch retractable power cord with polarized plug.
- Instruction booklet.
- Capacity : 1.5 liter/8 cups
- Weight : 7.80 lbs.
- Measurement: 11.75"w x 11.5"h x 11.75"d
Product Reviews
Be the first to write a review for Tiger JNP1500 Electric Rice Cooker and Food Steamer


text:
Guest reviews
Overall rating
6.2 Good
Based on 41 reviews
Recent reviews
- All reviews
- Positive
- Neutral
- Negative
Find reviews that mention:
Featuring free WiFi and a terrace, Doña Mercedes Hostel offers accommodation in Cebu City, 2,953 feet from Fuente Osmena Circle. Free private parking is available on site. Each room at this guest house is air conditioned and is fitted with a TV. Some rooms feature a seating area to relax in after a busy day. The rooms come with a private bathroom. There is a 24-hour front desk at the property. The guest house also offers car hire. Ayala Center Cebu is 1 miles from Doña Mercedes Hostel, while Colon Street is 1.6 miles from the property. The nearest airport is Mactan Cebu International Airport, 6.2 miles from the property.


text:
My Servicedesk Server is not able to send out emails after incident have been created.
Exception Message: -ERR Invalid user name or Password. Too Many Logon attempts. Exception Stack Trace:Quiksoft.EasyMail.POP3.POP3 AuthenticationException
The Mail server that is configured has set SMTP authentication to required. Servicedesk requires an open access to the server.
Configure your mail server to not require SMTP authentication.
Applies To
Servicedesk 7.0 MR2
Terms of use for this information are found in Legal Notices.
Terms of use for this information are found in Legal Notices.
Login to Subscribe
Please login to set up your subscription.
Get support for your product, with downloads, knowledge base articles, documentation, and more.
Maximize your product competency and validate technical knowledge to gain the most benefit from your IT investments.
Submit a suspected infected file to Symantec.
Report a suspected erroneous detection (false positive).
Set default language
Do you wish to save this as your future site?


text:
In my never ending quest to find the perfect cell phone I just traded in my iPhone for an AT&T Tilt 8925. The iPhone was lacking features in areas I used most such as email. It's my understanding that Windows Mobile 7 is supposed to take more of an iPhone approach, so I can wait until then. I'm excited about an old feature: Exchange synchronization. It's nice to have my contacts and calendar appointments update on the fly instead of having to sync with iTunes. Other features that made me switch include:
No Bcc capability
No MMS capability
No way to insert attachments in emails other than attaching a photo directly from the photo
Some email messages took a while to open if they had a large attachment
Only 1 email signature applied to all email accounts
Exchange support only via IMAP and no Exchange integration
Syncing only via iTunes
No ability to record videos
Closed device
When more of these features are baked into the iPhone, I'll be willing to give it another try. I enjoyed the overall user experience, but missed what I mentioned above.


text:
National 2 Science in the Environment
The National 2 Science in the Environment Course draws on elements of Biology, Chemistry and Physics. Learners engage in practical scientific activities, begin to develop scientific literacy through the use of scientific and environmental language in everyday contexts, and recognise the use and value of science in the environment and how it affects everyday life.
Science in the Environment homepage
Updates and announcements
Subject updates
Use the tabs below to open each section individually. Alternatively you can view allhide all the sections.
Mandatory information
Course Specification
This explains the overall structure of the Course, including its purpose and aims and information on the skills, knowledge and understanding that will be developed.
Unit Specifications
These provide an outline of what each Unit will cover within the Course and detail the Outcomes and Assessment Standards.
- Science in the Environment Resources, Forces and Energy (National 2) Unit Specification
- Science in the Environment Living Things (National 2) Unit Specification
- Science in the Environment Sustainable Lifestyles (National 2) Unit Specification
- Science in the Environment Managing an Environmental Area (National 2) Unit Specification
Advice and guidance
Course and Unit Support Notes
These provide advice and guidance for teachers/lecturers on learning, teaching and assessment within the Course and its Units.
Assessment support
Past Papers and Marking Instructions
Unit Assessment Support
These documents contain details of Unit assessment task(s), show approaches to gathering evidence and how the evidence can be judged against the Outcomes and Assessment Standards. Teachers/lecturers can arrange access to these confidential documents through their SQA Co-ordinator.
Understanding Standards materials
We are publishing examples of candidate evidence with commentaries as part of our Understanding Standards programme. These materials are for teachers and lecturers to help them develop their understanding of the standards required for assessment. As these materials become available, they are being published in the following locations:
- Available from our secure website Materials relating to Unit assessment, internally assessed components of Course assessment, and externally assessed components of Course assessment which are subject to visiting assessment. Teachers and lecturers can arrange access to these materials through their SQA Co-ordinator.
- Available from our Understanding Standards website Materials relating to externally assessed components of Course assessment, with the exception of those subject to visiting assessment.
More information on our Understanding Standards programme, can be found on our Understanding Standards page.


text:
Close Recently added item(s)
You have no items in your shopping cart.
* Made with high quality Swedish steel * Flawless side finish for superior edge quality * 10% more steel for added skate lean and incredible blade life * Pitch corrected profiles with no lumps or flat spots * Sold in PAIRS Only
Usually ships within 24 hours
This item is not eligible for promotions, sales or discounts
Why are certain items excluded from our sales?At Pure Hockey we do our best to bring you top-quality product at the best price. However, we aren't allowed to offer discounts or sales on certain products because of manufacturer restrictions. Here are some frequently asked questions about our limitations when it comes to offers and promotions. To be clear, restrictions on these items are not limited to Pure Hockey. These restrictions apply to ALL retailers.What does "MAP" stand for?
What does "MAP Restricted" mean?
Click here for full complete details on MAP Policy
No reviews yet for this product. Review This Product!
* Required Fields


text:
If you find yourself in need of parts to fix your Honda, then we can help you. All Honda drivers will agree that nothing but top quality replacement Wheel Lug Stud parts are the only parts that they will install on their automobile. Qualities such as fuel efficiency and economical pricing are what make your vehicle special, which is probably the reason why you drive one. Wheel Lug Stud failure can border on dangerous for almost anyone.
Your wheel hubs and wheel lug studs are susceptible to damage from bad weather, misalignments, and collisions. It is also common for a tire shop to accidentally break one of these parts on your Honda when changing tires. Regardless of the reason your Honda wheel lug studs need to be replaced, you need to get a well-made set to do the job right. After all, these provide the attachment point for your wheels to the hubs, so it is important that you only use the best.
With such a wide selection of quality Wheel Lug Stud parts for your Honda, you can use www.carpartsdiscount.com as your authoritative and expert supplier rather than the expensive local dealership. With friendly and knowledgeable customer service staff, CarPartsDiscount.com has the expertise to make it your last stop for quality replacement Wheel Lug Stud parts on the internet. Owning a vehicle that's famous for its a brand you can trust means only the best parts should be used for replacements and repairs. To find the correct Wheel Lug Stud parts for Honda Accord, Accord Crosstour, CR-V, CR-Z, CRX, Civic, Civic del Sol, Crosstour, Element, Fit, HR-V, Insight, Odyssey, Passport, Pilot, Prelude, Ridgeline, S2000, Wagovan and more, simply click your model from the list below.


text:
Obviously, you didn't buy your 210 unless you wanted to buy a variety of features and options and youthfulness both rolled up into one car, truck, or SUV. When your Nissan 210 rolled off the assembly line, it was destined for a person with discerning taste who wants long-lasting quality in their automobile. While it's not hard to locate replacement parts for Nissan vehicles, these days only the highest quality are required to maintain your automobile. Your Nissan dealership isn't the only place to buy genuine or original equipment quality replacement parts for your 210.
As far back as two thousand years ago, the Greeks and Romans were using hydraulic pressure to provide drinking water to cities. Your Nissan 210 has a brake master cylinder that creates a large amount of pressure for your braking system inside a very small space. This part compresses fluid inside the cylinder and sends it to your calipers and/or wheel cylinders. That is where the braking force from your Nissan 210 brake master cylinder is applied; as the calipers and wheel cylinders create the necessary friction so you can regain control of your automobile when necessary.
At Car Parts Discount, we have live customer service members available with enough expertise to help you select the correct Nissan 210 part for your project or repair. Trust in the value of the parts you get from carpartsdiscount.com and realize incredible savings on all your upcoming repairs. Don't let a broken Brake Master Cylinder spell the end of your car, truck, or SUV, and don't risk lowering its resale value by buying anything but the highest quality repair parts. Nissan 210 Brake Master Cylinder parts for 1982, 1981, 1980, 1979 vehicles are available here... just click your year to find them.


text:
Marlo Hampton Fired From Real Housewives Of Atlanta After Altercation
Rumors are swirling! Apparently tension between NeNe Leakes and Marlo Hampton has escalated after an alleged incident that happened over the weekend.
Sources say Marlo was given the pink slip. The reality star has been fired from the 'Real Housewives of Atlanta'. Allegedly the entire cast of RHOA attended Cynthia Bailey's bowling event. While the cameras were rolling, a verbal disagreement took place between NeNe and Marlo.
An insider revealed that the producers were trying to encourage a serious storyline invovling the apparent beef with Marlo and NeNe. The argument got so bad that they were in each others faces. NeNe felt like Marlo was 'putting on a show' for the cameras. NeNe then confronted one of the executive producers on the show, Carlos King. Allegedly NeNe curesed him out and poured water all over him because she felt that he was encouraging the drama between the two. NeNe then told the producers that either she leave or Marlo had to be fired. Due to the incident, Marlo was fired. This is all hearsay, however dfferent media sites are reporting that NeNe hit the producer. Here is what she had to say below:
Some people just belong n jail! See u court…I don't regret when I do things out of the goodness of my heart! It's sad when ppl can't see ur heart & all that you've done 2 help them….I don't know 1 person on this earth that is worth me hitting! The most I will do is hit u wit the court system…U can't throw every dog a bone because they might bite your hand #lessonlearned
Interesting!!! We will keep you updated as the story enfolds. Do you think the show will remain popular with Marlo no longer being on the show? What are your thought?
Source: thejasminebrand


text:
Wyckoff Public Schools
K-8 Developmental School Counseling Programs
The Wyckoff School Counseling Program recognizes that since students develop emotionally, socially and educationally, the Program must address the issue of total growth and learning for each child. Activities to foster this growth and learning must therefore occur in a developmental comprehensive sequence through the grades.
Program goals include:
These goals are addressed through an organized scope and sequence of activities implemented by the school counselors and teachers, working together and/or independently. These curriculum activities include:
While this program is for all students, we recognize that some students have needs that may require special attention/activities. For these students, responsive activities include:
District parents and teachers are provided with nationally recognized speakers and programs on issues such as communication, self esteem, responsibility and acceptance of individual differences at least once a year. Counselors provide informational and support workshops for parents regularly through the year on topics appropriate to specific grade levels. District in service for teachers on applicable topics such as Attention Deficit Disorder, Cooperative Discipline, diversity/tolerance and acceptance of individual differences are also provided.
Additionally, leadership opportunities are provided, in each of our schools, to build confidence, self esteem and character through participation as student guides, on Student Council, student FLOW exchange and the Eisenhower Service Project (students perform 15 hours of community service to improve and encourage student/community relations).


text:
Items in Cart:
Sell Your Property Today
Reach hundreds of thousand of potential buyers who visit bidorbuy every month. List your property for sale now!
Sell Now
A Closer Look at Jeggings
Are they leggings that look like jeans or jeans that look like leggings? Many fashionistas develop a headache just thinking about it!
A Look At Jeggings
Choosing The Right Braai
We have everything you need to know about becoming the ultimate braai aficionado. If you are in the market for a new braai, we have weighed up the pros and cons of kettle, flat top and gas braais to make the search a lot easier.
The Right Braai for You
Best Smartphones 2016
If you are looking for more bang for your buck, you may want to look at the best smartphones from last year. They will be cheaper and they perform well.
Best Smartphones
Guitar Hero 6: Warriors of Rock - Guitar Bundle (Xbox 360)
Format: Games - XBox360 - Music
We will dispatch item within 5-10 working days. Pre-release items will be dispatched on release date. See Shipping and Payment tab for additional information
We will replace or issue a no questions asked full refund for defective or damaged items.
15 Days: We guarantee the accuracy of item description, ISBN or EAN code as applicable and condition of item as specified in the listing.


text:
All Categories
Bookstore Categories
Item description for Ancient West & East by Gocha R. Tsetskhladze...This new journal from Brill makes many important promises to all scholars interested in the cultures of the ancient Mediterranean and the Near East and the interactions between them. ... By opening a regular avenue for cooperation and conversation among scholars from many disciplines and countries, AWE has a real potential for fulfilling the promises it makes. BMCR 2003.08.09
Promise Angels is dedicated to bringing you great books at great prices. Whether you read for entertainment, to learn, or for literacy - you will find what you want at promiseangels.com!
Item Specifications...
More About Gocha R. Tsetskhladze
Product Categories
Reviews - What do customers think about Ancient West & East?
Be the first to write a review about Ancient West & East
Ask A Question or Provide Feedback regarding Ancient West & East
Add This Product Widget To Your Website
Looking to add this information to your own website? Then use our Product Widget to allow you to display product information in a frame that is 120 pixels wide by 240 pixels high.
|Order toll-free weekdays 10am thru 10pm EST by phone: 1-888-395-0572 (Lines are closed on holidays & weekends.)
|Customer Service | My Account | Track My Orders | Return Policy | Request Free Catalog | Email Newsletter


text:
Sex workers and their allies are marching in Vancouver today to protest federal laws criminalizing prostitution.
It's been a year since the federal government passed new laws targeting prostitution.
Kerry Porth of the Pivot Legal Society says says since then the job has gotten riskier – pushing it further underground.
"If you can't communicate about what you're doing, that communication is going to take place in darkly lit back alleys. Sex workers who work indoors are finding it very difficult to advertise and so they're having to negotiate with clients once they arrive at their door – and that's much more dangerous."
Porth also says the law isolates sex workers by targeting anyone they work with who financially benefits.
She says advocates are organizing to mount a court challenge of the law.


text:
The Justice Department filed an antitrust lawsuit against the nation's largest dairy company Friday, alleging that Dean Foods Co. purchased a smaller dairy company in Wisconsin to quash competition and drive up milk prices.
The lawsuit - filed in concert with attorneys general from Illinois, Michigan, and Wisconsin - seeks to undo Dean Foods' 2009 purchase of Foremost Farms USA's Consumer Products Division and to require Dean to give 30 days' notice before all future acquisitions.
The suit signals a shift of antitrust policy in Washington, where regulators have promised to take more aggressive action in an agricultural sector dominated by big firms that have consolidated market share over the last two decades.
"This is highly unusual," said dairy analyst Pete Hardin, who publishes The Milkweed industry newsletter. "This is the first bark we've heard from (the justice department's) antitrust division on food issues in a very long time. I think there are a lot of rabbits in the field where they're hunting."
Dallas-based Dean Foods released a statement saying it was "disappointed" the department took action on a deal closed 10 months ago. The company said it was confident a review will reveal "competition is alive and flourishing in Wisconsin."
Wisconsin's Democratic U.S. senators praised the Justice Department's announcement.
"If the allegations are proven to be true, today's lawsuit will result in lower prices for consumers and more competitive choices for dairy farmers in Wisconsin," Herb Kohl said in a statement.
Russ Feingold said he's been pressing for more competition in the dairy industry and has flagged antitrust concerns about the acquisition.
"This consolidation would be terrible for Wisconsin consumers and school districts, as well as Wisconsin farmers," he said in a statement. "After years of inaction by the DOJ Antitrust Division despite growing concern about unfair competition in many agriculture markets, this is a welcome change."
Dean Foods has acquired more than 100 smaller companies since 1996, according to the lawsuit. Its April 2009 purchase of Foremost was small enough that the company did not have to seek prior approval from the department.
The deal gave Dean two dairy processing plants in Wisconsin, and left many school districts with only one milk supplier, according to the lawsuit. Dean gained 57% market share in parts of Michigan, Illinois and Wisconsin through the deal.
The lawsuit portrays the acquisition as a strategic move to eliminate a strong competitor.
Starting in 2006, Foremost began to lose customers and slashed its prices to win back business from Dean Foods, according to the suit.


text:
|incl. VAT
|excl. VAT
|Extended warranty + 1 year £24.10 Extended warranty + 1 year
|Return products within two months £12.05 Possibility to return products within two months
OFFSHORE Limited Ballast are unusual, originally designed men's watches. In essence combine resistance to extreme sports coping with social grace . Despite the modest size, broad rim of the dial face a really robust, which is not just a matter of appearance. Precision housing made of stainless steel will survive any outdoor situation - bumps, dirt, snow and water.
Round dial is protected mineral glass which is highly resistant to scratching. On the face are clearly marked with minute descriptions indices on which show in detail processed hands. The watch is powered by a battery-quality quartz movement. Will serve you well date stamp and stopwatch with the ability to measure up to 30 minutes with high accuracy.
Additional information:
Men's Wrist Watches
Analogue time display
Date Stamp
Stopwatch (accuracy 1.1 seconds, max. 30 minutes)
Specifications can be changed without notice. Images are for illustrative purposes only. Retail Price (MSRP) means the manufacturer's/supplier's suggested retail price.
Link to Manufacturer's Website: Enter link to the external review


text:
Author has written 1 story for Twilight.
I guess I popped my writer's cherry, but I still can't see myself writing very often. I have a newfound respect for the bravery required to post a story. However, I'm an avid reader, and that tends to keep me plenty entertained. I'm always looking for recommendations, so please share!
I'm a beta with PTB. I'm always disappointed when a great story is ruined by distractingly poor grammar and punctuation. I experienced while I was writing for the first time that it is really easy to let mistakes slip and that a seond pair of eyes is absolutely necessary. I volunteer with PTB to help alleviate that. It's a great service; check them out. Also, I'm terrible at reviewing, so this helps me feel like I am contributing; I get so much, I like to give back a little. Plus, I really hate poor grammar and punctuation! They are always looking for help. Join us.
FYI I use my favorites as bookmarks for stories I have read and things I plan to read. I do delete anything I wouldn't recommend, but not all of these I can yet adhere my stamp of approval.
Follow me on twitter @MeteorMuse


text:
Should the US Stay in Afghanistan?
This Sunday, General David Petraeus will go on a media offensive in which he is expected to make the case for why we should not rush the withdrawal from Afghanistan.
However, this comes at a time when public support for the war is rapidly dwindling. Many Americans have fixed their expectations on what the president pledged in December 2009 when he ordered more troops to Afghanistan: "These additional American and international troops will allow us to accelerate handing over responsibility to Afghan forces and allow us to begin the transfer of our forces out of Afghanistan in July of 2011."
But Obama's promise to begin the withdrawal of troops from Afghanistan in July 2011 was notably sparse on the details of how many troops will withdraw, and how quickly.
Speaking that same day, back in December, Obama added, "We will execute this transition responsibly, taking into account transitions on the ground. We'll continue to advice and assist Afghan security forces to ensure that they can succeed over the long haul. But it will be clear to the Afghan government and more importantly to the Afghan people, that they will ultimately be responsible for their own country."
So how do we know when it's time to leave? Will there ever be a right time? And how do we reconcile our need to "win" this war with our desire to end it?
Joining us is Richard Haass, President of the Council on Foreign Relations and author of "War of Necessity, War of Choice."
JOHN HOCKENBERRY: Good morning everyone. We certainly know that General David Petraeus commands U.S. forces in Afghanistan – that is his new job – sort of his old job as well.
LYNN SHERR: Yes
John: It is also his mission to define and crystallize and articulate the message and mission of the U.S. in Afghanistan as well.
SHERR: You could say that is in his job description.
HOCKENBERRY: He will be doing a lot of messaging this weekend. If you watch the talk-shows General David Petraeus will begin to lay out the argument for what is suggested to be a delay in the scheduled draw-down in Afghanistan. Troops are supposed to begin coming out of Afghanistan by 2011. Here is an excerpt from an interview that NBC will air in its entirety over the weekend. David Petraeus.
"General Petraeus: I think our job is again to show those in Washington that there is progress being made and to do that we have to build on the progress that has been established so far."
HOCKENBERRY: Progress in a war that is already America's longest and that the president has called a "war of necessity." We are joined by Richard Haas, president of the Council on Foreign Relations and author of "War of Necessity, War of Choice." Good morning Richard.
RICHARD HAASS: Good morning, John.
HOCKENBERRY: So you just heard from the perspective of a first Lieutenant, who has come back from Afghanistan that once you say it is a war of necessity – you really don't have the option to say all of a sudden it is now a war of choice. It seems like David Petraeus reflects that sentiment as well. What do you think?
HAASS: Well you may not say it but just because you don't say things doesn't make it so. It is interesting to look back at history. The Korean War obviously began as a war of necessity when the North Koreans invaded in June of 1950. But when MacArthur and Truman made the decision not simply to reverse the aggression but to go north of the 38th parallel and try to reunify the country, they turned what had been a war of necessity into a war of choice. I am simply suggesting President Obama has done the same thing with Afghanistan. It began as a war of necessity after 9/11, when we were entirely right to oust the Taliban, who had facilitated Al Qaida. But when we decided a year and a half ago to triple our troop levels, to go after the Taliban, to essentially become a protagonist in Afghanistan's civil war, to try to nation-build and rebuild a central government and its army; that was a real strategic turn, so this has become a war of choice. That doesn't necessarily mean it's wrong. I for one disagree, others disagree with me. But it is something fundamentally different.
HOCKENBERRY: Alright, then if we were to pull out, what is the argument for pulling out in your view? Is it because Afghanistan is no longer a threat, that our presence there has changed the game in Afghanistan in some fundamental way or that it's pointless to nation-build in Afghanistan to prevent the Taliban and terrorists from finding a safe haven there, if we don't also rebuild Somalia, and Sudan, and Yemen and half a dozen other places around the world?
HAASS: Well, just to be clear, I don't favor a complete withdrawal, I think that would be a mistake. But I do think there are things we can do, just simply at a more modest level than what we are doing now. I don't think we need 100,000 troops, I don't think we need to try to strengthen the central government to the extent we are and so forth. So I think there are real alternatives to what are doing, but to take your basic point I don't think the U.S. interests in Afghanistan warrant anything close to the scale of what we are doing. The administration keeps talking about two fundamental reasons for what we are doing. One is to make sure that Al Qaida does not use Afghanistan again as a base. Well they're not. The head of the CIA, Leon Panetta, recently estimated that there is only between 50 and 100 members of Al Qaida left in Afghanistan. Well, we clearly don't need a ratio of 1,000 to 1 in troops in order to deal with Al Qaida. And secondly the argument is that we shouldn't allow Afghanistan to be used to undermine its far more important neighbor Pakistan. Well, I agree but what is going on in Pakistan is the biggest threat to Pakistan and the Pakistanis themselves are helping groups like the Taliban in Afghanistan. So I just don't see where our policy adds up.
HOCKENBERRY: How does a government – the Obama administration in the case in point here – disengage from the very powerful sentiment (and you heard it expressed by First Lieutenant Galeti) there, who we are going to talk to in a moment, that we have already spent so much of an investment in Afghanistan either in terms of blood and treasure, or just in terms of policy, we can't withdraw now. An argument that we heard in Vietnam. It is very difficult for presidents to pull away from that.
HAASS: Well, I don't think you honor commitments and make good on commitments by simply continuing them if you are not persuaded it's the right thing to do. These are extraordinarily expensive undertakings, not just financially but obviously in terms of military commitments and in terms of human life. So I would suggest that you only keep doing what you are doing if you are persuaded it is the right thing to do. And again, I am not favoring withdrawal but I do think there are ways we need to dramatically downsize our involvement. We could reorient it away from support for the central government, which is corrupt and weak. We should start working with local commanders, this is the nature of Afghanistan where people on the periphery are often far more powerful than people in Kabul, in the center.
HOCKENBERRY: Hamid Karzai, the president of Afghanistan, has suggested in an interview with Al Jazeera that NATO thinks that the war is in the villages of Afghanistan, against everyone wearing a turban or a beard and that NATO, until it changes that strategy, is going to fail in Afghanistan. Do you buy that argument?
HAASS: I'm not quite sure what the point of his argument is. Again, I don't think we have a war with Afghanistan. I don't think we have a war with the 50 percent or so of the people in Afghanistan who are Pashtun. We ought to have a much narrower goal to simply make sure that Afghan soil is not used as a base for terrorists or its insurgents who are trying to undermine a neighbor. The problem is we don't have a partner in Kabul. You just mentioned President Karzai. I would not describe him as much of a partner, not simply because of the corruption, but he is obviously most intent on preserving his own position. And we don't have much of a partner in Pakistan which essentially sees Afghanistan as an arena to struggle against its larger neighbor India. So we've got a real problem here, where our two so-called partners are in effect something quite different.
HOCKENBERRY: Finally Richard Haass, you know I may be naive here but I actually don't fear anyone in Afghanistan coming over and harming me or my family here in the U.S. If that is the case, if you believe that, and on some level if you believe that it is really not the right thing to do, to maintain a large scale occupation in Afghanistan, why not just completely withdraw? You say you don't favor a withdrawal, why not?
HAASS: We should do there something much more akin to what we are doing in places like Somalia and Yemen, have a count-the-terrorist strategy – keep any terrorist there at bay. But I wouldn't do a complete withdrawal, I would simply again dramatically downscale our involvement there. It is simply one of the places in the world we ought to be concerned with, but it's not a place we should be preoccupied with.
HOCKENBERRY: Richard Haass, President of the Council on Foreign Relations, Author of "War of Necessity, War of Choice: A Memoir of Two Iraq Wars." He'll be looking like many of the rest of us at the statements of General David Petraeus, who will be making the case to possibly delay withdrawal from Afghanistan past 2011. Richard Haass thanks so much.
HAASS: Thank you John.


text:
Class: Leptins
Brands: Myalept
Warning: Risk of anti-metreleptin antibodies with neutralizing activity and risk of lymphoma.
See full prescribing information for complete boxed warning.1
Anti-metreleptin antibodies with neutralizing activity have been identified in patients treated with metreleptin. The consequences are not well characterized but could include inhibition of endogenous leptin action and loss of metreleptin efficacy. Worsening metabolic control and/or severe infection have been reported. Test for anti-metreleptin antibodies with neutralizing activity in patients with severe infections or loss of efficacy during metreleptin treatment. Contact Aegerion Pharmaceuticals, Inc. at 1-866-216-1526 for neutralizing antibody testing.1
T-cell lymphoma has been reported in patients with acquired generalized lipodystrophy, both treated and not treated with metreleptin. Carefully consider the benefits and risks of treatment with metreleptin in patients with significant hematologic abnormalities and/or acquired generalized lipodystrophy.1
Metreleptin is available only through a restricted program called the Myalept REMS Program.1
FDA approved a REMS for metreleptin to ensure that the benefits outweigh the risk. The REMS may apply to one or more preparations of metreleptin and consists of the following: elements to assure safe use and implementation system. See the FDA REMS page () or the ASHP REMS Resource Center ().
Metreleptin is a recombinant human leptin analog.1
Uses for Metreleptin
Metreleptin has the following uses:
Metreleptin is a leptin analog indicated as an adjunct to diet as replacement therapy to treat the complications of leptin deficiency in patients with congenital or acquired generalized lipodystrophy.1
Metreleptin has the following limitations of use:
The safety and effectiveness of metreleptin for the treatment of complications of partial lipodystrophy have not been established.1
The safety and effectiveness of metreleptin for the treatment of liver disease, including nonalcoholic steatohepatitis (NASH), have not been established.1
Metreleptin is not indicated for use in patients with HIV-related lipodystrophy.1
Metreleptin is not indicated for use in patients with metabolic disease, without concurrent evidence of generalized lipodystrophy.1
Metreleptin Dosage and Administration
Metreleptin is available in the following dosage form(s) and strength(s):
Metreleptin is supplied as a sterile, white, solid, lyophilized cake of 11.3 mg metreleptin per vial to deliver 5 mg per mL when reconstituted with 2.2 mL of bacteriostatic water for injection (BWFI) or preservative-free sterile water for injection (WFI).1
It is essential that the manufacturer's labeling be consulted for more detailed information on dosage and administration of this drug. Dosage summary:
Administer as a subcutaneous injection once daily after the lyophilized cake is reconstituted with BWFI or preservative-free sterile WFI.1
The recommended daily dosages are: 1
Body weight 40 kg or less: starting dose 0.06 mg/kg/day, increase or decrease by 0.02 mg/kg to a maximum daily dose of 0.13 mg/kg.1
Males greater than 40 kg body weight: starting dose 2.5 mg/day, increase or decrease by 1.25 mg to 2.5 mg/day to a maximum dose of 10 mg/day.1
Females greater than 40 kg body weight: starting dose 5 mg/day, increase or decrease by 1.25 mg to 2.5 mg/day to a maximum dose of 10 mg/day.1
Cautions for Metreleptin
General obesity not associated with congenital leptin deficiency.1
Hypersensitivity to metreleptin.1
Risk for Development of Antibodies That Neutralize Endogenous Leptin and/or Metreleptin
Anti-metreleptin antibodies with in vitroneutralizing activity to leptin associated with adverse events consistent with loss of endogenous leptin activity and/or loss of efficacy have been identified in two patients with generalized lipodystrophy treated with metreleptin (severe infections, increases in HbA1c and triglycerides), and in three patients without lipodystrophy who received metreleptin in clinical studies (excessive weight gain, development of glucose intolerance or diabetes mellitus). The clinical implications associated with development of anti-metreleptin antibodies with neutralizing activity are not well characterized at this time due to the small number of reports. Test for anti-metreleptin antibodies with neutralizing activity in patients who develop severe infections or show signs suspicious for loss of metreleptin efficacy during treatment. Contact Aegerion Pharmaceuticals, Inc. at 1-866-216-1526 for neutralizing antibody testing of clinical samples.1
Three cases of T-cell lymphoma have been reported in the metreleptin lipodystrophy program; all three patients had acquired generalized lipodystrophy. Two of these patients were diagnosed with peripheral T-cell lymphoma while receiving metreleptin. Both had immunodeficiency and significant hematologic abnormalities including severe bone marrow abnormalities before the start of metreleptin treatment. A separate case of anaplastic large cell lymphoma was reported in a patient receiving metreleptin who did not have hematological abnormalities before treatment.1
Lymphoproliferative disorders, including lymphomas, have been reported in patients with acquired generalized lipodystrophy not treated with metreleptin. A causal relationship between metreleptin treatment and the development and/or progression of lymphoma has not been established. Acquired lipodystrophies are associated with autoimmune disorders, and autoimmune disorders are associated with an increased risk of malignancies including lymphomas.1
The benefits and risks of metreleptin treatment should be carefully considered in patients with acquired generalized lipodystrophy and/or those with significant hematologic abnormalities (including leukopenia, neutropenia, bone marrow abnormalities, lymphoma, and/or lymphadenopathy).1
REMS Program
Metreleptin is available only through a restricted distribution program under a Risk Evaluation and Mitigation Strategy (REMS), called the Myalept REMS Program, because of the risks associated with the development of anti-metreleptin antibodies that neutralize endogenous leptin and/or metreleptin and the risk for lymphoma.1
Notable requirements of the Myalept REMS Program include the following: 1
Prescribers must be certified with the program by enrolling and completing training.1
Pharmacies must be certified with the program and only dispense metreleptin after receipt of the Myalept REMS Prescription Authorization Form for each new prescription.1
Further information is available at or 1-855-6MYALEPT.1
Hypoglycemia with Concomitant Use with Insulin and Insulin Secretagogues
Dosage adjustments, including possible large reductions, of insulin or insulin secretagogue (e.g., sulfonylurea) may be necessary in some patients to minimize the risk of hypoglycemia. Closely monitor blood glucose in patients on concomitant insulin therapy, especially those on high doses, or insulin secretagogue (e.g., sulfonylurea), when treating with metreleptin.1
Leptin plays a role in immune system homeostasis. Acquired lipodystrophies are associated with autoimmune disorders including autoimmune hepatitis and membranoproliferative glomerulonephritis. Cases of progression of autoimmune hepatitis and membranoproliferative glomerulonephritis (associated with massive proteinuria and renal failure) were observed in some patients with acquired generalized lipodystrophy treated with metreleptin. A causal relationship between metreleptin treatment and the development and/or progression of autoimmune disease has not been established. The potential benefits and risks of metreleptin treatment should be carefully considered in patients with autoimmune disease. 1
There have been reports of generalized hypersensitivity (e.g., anaphylaxis, urticaria, generalized rash) in patients taking metreleptin. If a hypersensitivity reaction occurs, instruct the patient to promptly seek medical advice regarding discontinuation of metreleptin.1
Benzyl Alcohol Toxicity
Metreleptin contains benzyl alcohol when reconstituted with BWFI. Metreleptin contains no preservative when reconstituted with preservative-free sterile WFI. Preservative-free sterile WFI is recommended for use in neonates and infants. The preservative benzyl alcohol has been associated with serious adverse events and death in pediatric patients, particularly in neonates and premature infants. 1
Specific Populations
Pregnancy Category C. 1
There is a program that monitors outcomes in women exposed to metreleptin during pregnancy. Women who become pregnant during metreleptin treatment are encouraged to enroll. Patients or their physicians should call 1-855-6MYALEPT to enroll.1
There are no adequate and well-controlled studies of metreleptin in pregnant women. All pregnancies, regardless of drug exposure, have a background rate of 2% to 4% for major malformations and 15% to 20% for pregnancy loss. In a pre- and postnatal development study in mice, administration of metreleptin caused prolonged gestation and dystocia resulting in maternal death during parturition and lower survival of offspring in the immediate postnatal period at doses starting approximately at the maximum recommended clinical dose. Because animal reproduction studies are not always predictive of human response, metreleptin should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.1
The contribution of metreleptin to obstetrical risks and complications is unknown compared with those already documented in the lipodystrophy patient population (e.g., gestational diabetes, macrosomia, eclampsia, intrauterine growth retardation, intrauterine death, and miscarriage).1
The effects of metreleptin on labor and delivery in pregnant women are unknown. In an in vitro study of human myometrial tissue exposed to a recombinant leptin, human uterine contractility was inhibited. Furthermore, prolonged gestation and dystocia were observed in animal studies with metreleptin.1
Metreleptin administered to pregnant mice during the period of organogenesis was not teratogenic at doses ranging between 7- and 15-fold the maximum recommended clinical dose, based on body surface area of a 20- and 60-kg patient, respectively.1 In a pre- and postnatal development study in mice, metreleptin administered at doses of 3, 10, and 30 mg/kg (approximately 1-, 5-, and 15-fold the clinical dose for a 60-kg subject, based on body surface area) from gestation day 6 to lactation day 21 caused prolonged gestation and dystocia at all doses, starting at approximately the maximum recommended clinical dose. Prolonged gestation resulted in the death of some females during parturition and lower survival of offspring within the immediate postnatal period. Consistent with metreleptin pharmacology, decreased maternal body weight was observed from gestation throughout lactation at all doses and resulted in reduced weight of offspring at birth, which persisted into adulthood. However, no developmental abnormalities were observed and reproductive performance of the first or second generations was not affected at any dose.1 Placental transfer of metreleptin into the fetus was low (approximately 1%) following subcutaneous dosing.1
Nursing Mothers
It is not known if metreleptin is present in human milk. Endogenous leptin is present in human milk. Because of the potential for serious adverse reactions (including possible adverse reactions related to passage of anti-metreleptin antibodies) in nursing infants from metreleptin a decision should be made whether to discontinue nursing or discontinue the drug, taking into account importance of drug to the mother.1
Pediatric Use
The metreleptin study included a total of 35 pediatric patients (73%) with an age range from 1 to 17 years. No clinically meaningful differences were observed in the efficacy and safety of metreleptin between pediatric and adult patients.1
Metreleptin contains benzyl alcohol when reconstituted with BWFI. Metreleptin contains no preservative when reconstituted with preservative-free sterile WFI. Preservative-free sterile WFI is recommended for use in neonates and infants. The preservative benzyl alcohol has been associated with serious adverse events and death, particularly in pediatric patients. The "gasping syndrome" (characterized by central nervous system depression, metabolic acidosis, gasping respirations, and high levels of benzyl alcohol and its metabolites found in the blood and urine) has been associated with benzyl alcohol dosages >99 mg/kg/day in neonates and low-birth weight infants. Additional symptoms may include gradual neurological deterioration, seizures, intracranial hemorrhage, hematologic abnormalities, skin breakdown, hepatic and renal failure, hypotension, bradycardia, and cardiovascular collapse.1
Although normal therapeutic doses of this product deliver amounts of benzyl alcohol that are substantially lower than those reported in association with the "gasping syndrome," the minimum amount of benzyl alcohol at which toxicity may occur is not known. Premature and low-birth-weight infants, as well as patients receiving high dosages, may be more likely to develop toxicity. Practitioners administering this and other medications containing benzyl alcohol should consider the combined daily metabolic load of benzyl alcohol from all sources. When reconstituted with 2.2 mL of BWFI, metreleptin contains 1.76 mg of benzyl alcohol per mg of metreleptin or 9 mg of benzyl alcohol per mL of reconstituted product. 1
Geriatric Use
Clinical trials of metreleptin did not include sufficient numbers of subjects aged 65 and over (n=1) to determine whether they respond differently from younger subjects. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.1
Common Adverse Effects
Most common in clinical trials (≥10%): headache, hypoglycemia, decreased weight, abdominal pain.1
Drug Interactions
Specific Drugs
It is essential that the manufacturer's labeling be consulted for more detailed information on interactions with this drug, including possible dosage adjustments. Interaction highlights:
Please see product labeling for drug interaction information.
Mechanism of Action
Adipocytes store lipids to meet the fuel requirements of non-adipose tissues during fasting. In patients with generalized lipodystrophy, the deficiency of adipose tissue leads to hypertriglyceridemia and ectopic deposition of fat in non-adipose tissues such as liver and muscle, contributing to metabolic abnormalities including insulin resistance. Native leptin is a hormone predominantly secreted by adipose tissue that informs the central nervous system of the status of energy stores in the body. In patients with generalized lipodystrophy, leptin deficiency, resulting from the loss of adipose tissue, contributes to excess caloric intake, which exacerbates the metabolic abnormalities.1
Metreleptin for injection exerts its function by binding to and activating the human leptin receptor (ObR), which belongs to the Class I cytokine family of receptors that signals through the JAK/STAT transduction pathway.1
Advice to Patients
Patient Counseling Information
See FDA-approved Patient Labeling.1
Advise patients that neutralizing antibodies may result in loss in activity of endogenous leptin or loss of efficacy of metreleptin. Advise patients on symptoms or signs that would warrant antibody testing.1
Advise patients that lymphoma has been reported in patients both treated and not treated with metreleptin. Advise patients on symptoms or signs that indicate changes in hematologic status and the importance of routine laboratory assessments and physician monitoring.1
Advise patients that the risk of hypoglycemia is increased when metreleptin is used in combination with insulin or an insulin secretagogue (e.g., sulfonylurea). Explain the symptoms, treatment, and conditions that predispose to development of hypoglycemia to the patient. Advise patients who are taking concomitant insulin, especially those on high doses, or an insulin secretagogue, to closely monitor blood glucose. Hypoglycemia management should be reviewed and reinforced when initiating metreleptin therapy, particularly when concomitantly administered with insulin or an insulin secretagogue.1
Advise patients that worsening of autoimmune disease has been reported during the clinical study of metreleptin. Advise patients with a history of autoimmune disease on symptoms or signs that indicate exacerbation of underlying autoimmune disease and the importance of routine laboratory assessments and physician monitoring.1
Inform patients that hypersensitivity reactions have been reported during use of metreleptin. If symptoms of hypersensitivity reactions occur, patients should seek medical advice.1
Advise nursing mothers that breastfeeding is not recommended with metreleptin use.1
Inform patients that each vial of metreleptin requires reconstitution with BWFI or preservative-free sterile WFI, and administration as subcutaneous injection using a syringe and needle. Injections can be given at any time of the day, with or without meals.1
Patients and caregivers should receive proper training in how to prepare and administer the correct dose of metreleptin prior to self-administration. The first dose of metreleptin should be administered by the patient or caregiver under the supervision of a qualified healthcare professional.1
Advise patients on injection technique, dosing regimen, and the importance of proper storage of metreleptin. Care should be taken to avoid intramuscular injection, especially in patients with minimal subcutaneous adipose tissue.1
Advise patients to read the instructions for use for complete administration instructions. The metreleptin medication guide and instructions for use should be reviewed before starting therapy and each time the prescription is refilled.1
When discontinuing metreleptin in patients with a history of pancreatitis and/or severe hypertriglyceridemia, instruct patients to taper their dose over a one-week period. Advise patients that additional monitoring of triglyceride levels and possible initiation or dose adjustment of lipid-lowering medications may be considered.1
Additional Information
AHFS First Release. For additional information until a more detailed monograph is developed and published, the manufacturer's labeling should be consulted. It is essential that the manufacturer's labeling be consulted for more detailed information on usual uses, dosage and administration, cautions, precautions, contraindications, potential drug interactions, laboratory test interferences, and acute toxicity.
Excipients in commercially available drug preparations may have clinically important effects in some individuals; consult specific product labeling for details.
Please refer to the ASHP Drug Shortages Resource Center for information on shortages of one or more of these preparations.
Dosage Forms
Brand Names
Injection, Powder, Lyophilized, For Solution
11.3 mg
Aegerion Pharmaceuticals Inc.
AHFS Drug Information. © Copyright 2017, Selected Revisions September 1, 2015. American Society of Health-System Pharmacists, Inc., 4500 East-West Highway, Suite 900, Bethesda, Maryland 20814.
1. Aegerion Pharmaceuticals, Inc. Myalept (metreleptin) SUBCUTANEOUS prescribing information. 2015 Sept.
More about metreleptin
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Support Group
- En Español
- 0 Reviews – Add your own review/rating
- Drug class: miscellaneous metabolic agents
Consumer resources
Professional resources
Other brands: Myalept


text:
Hotel Remauro
No prices found through our partners. Please contact the business directly or check some of our recommended alternatives.
Travelers also looked at:
TripAdvisor Reviews Hotel Remauro Cibiana di Cadore
Travel Blogs from Cibiana di Cadore
On our way to Austria...
... practically on the border - so we'll be visiting places in Germany and Austria and driving between the two. E is really looking forward to the next stage of the trip, as I have promised to take him on a Sound of Music tour - he'll love it..... especially the sing-a-long bit ...
Out walking next to Marmolada
... day walking with a picnic up in the mountains. Our legs hadn't quite recovered from yesterday's hike - but once we had warmed up, from the climb straight up from the car park, we were fine. Thankfully we didn't loose the path too much this time - so managed to get the whole walk done in the daylight !! :) - yet another day of amazing views - fab ...
Walking in the Dolomites
We arrived in Campitello yesterday evening, and woke today to some more fantastic weather for early November. It is about 16-17 degrees with clear blue skies, making the visibility fantastic. This was great as we had been advised to head up into the Duron valley just behind our apartment building and then head over the hills and back to Campitello. It was a great day for walking, but we hadn't ...
Welcome to the Dolomites
... grandparents.
Le Palue provides a life for only a few people and reminds me of nothing. Seldom a car drives by or a plane flies overhead in the distance. This place is tranquil, inviting, and completely at peace. As the sun sets behind Marmolada, queen of the Dolomites, we are left with another mark of Italy's never-ending splendor. It is very easy to understand how people can spend their lives in such a way.
Mountain bliss
UNESCO: History of the Dolomites
... in some routes, like the Paternkofel (a peak near Toblach in the Dolomites), you even use them to ascend to the summit. These are called Klettersteigen, or fixed "climbing-routes". In the ascent of the Paternkofel, you climb through a tunnel used in WWI for almost half of the ascent.
The Dolomitic and Tiroler regions, while in Northern Italy, are split almost 50/50 between German and Italian speakers. The area ...


text: Edited by Sesto: 3/4/2014 11:05:18 AM 62 4 Sesto Best Fictional Female Book, movie, anime, game, whatever. Pic related. English #Offtopic #books #Anime #movies #SestoIsACoolGuy #fate Comment Reply Start Topic Report Add more answer options Posting in language: English Français Español Deutsch Italiano 日本語 Português (Brasil) B I U Quote Link Named Link Spoiler Armory Forum Category Destiny Feedback Help Community Recruitment Gaming OffTopic Forum Sub-Category Post a Poll Question Post Cancel Edit Create Fireteam Post Play nice. Take a minute to review our Code of Conduct before submitting your post. View Entire Topic


text:
Time, forever omniscient, forever there,
Many enemies, few friends, that observe and stare
Into its face, into its exquisite eye,
As it sits on its throne to cry
Seconds and minutes and hours on end,
Too low for Greed, too high to bend,
It simply sits, no tears to lend.
Time, The master, Supreme,
Sits confused, mystified, in a dream,
As others seek to seize its gift, its treasure,
Live to feed and writhe upon Time for pleasure.
Yet all fail, as, through the smoke,
Time hears their cries as they fall or choke,
Begging Time to aid them, and release its yolk.
Time, who beats out its own rhythm and chords,
Looks beyond, and sees death beside it, bored.
'Won't you accept a little company?' Says he,
'Hmm...' Time replies, 'I shall think, we'll see.'
Death smiles, leading Time up to dance,
Both intertwine, the pace quickens as they prance,
Above destruction and grief, both in a trance.
Time, Ignorant though just and pure,
Knew not that the leeches lay beneath, seeking to lure
Time to reveal itself; Time cleverly presented them with a gift that tricked;
Three hands that clicked, Twelve symbols they licked,
'What does this mean?' Their countenace's fell.
'Well,' said Time, looking on, 'It is my gift. You cannot tell
What conjures beyond me. until then, if you wish, I'll leave you to dwell.'


text:
Lei Garden
3/F, IFC Pudong, 8 Shiji Da Dao, near Lujiazui Huan Lu 世纪达到8号国金IFC商场3楼, 近陆家嘴环路 +86 21 5106 1688
11:30 a.m. to 3 p.m.; 6 to 11:30 p.m.
Hong Kong's Lei Garden group opened its first Shanghai store in August and already the place is racking up praise from the city's diners.
On dianping.com, it earns an admirable 26 out of 30 for flavor.
It's already impossible to grab a spontaneous dinner here for one reason: this the best dim sum Shanghai.
Management has done a good job -- Lei Garden Shanghai is as good as the original Lei Garden Hong Kong.
The crystal shrimp hargow features incredibly fresh, firm shrimp bursting with umami flavor.
The radish pastries are fabulous. The traditional layered pastry is virtually greaseless, the most delicious rendition of the dish you'll find in Shanghai.
The red-braised chicken feet get another thumbs up, along with the crispy duck and Macau-style pork.
Lei Garden's daily bao tang is homey Cantonese cuisine at its finest. You have to reserve it ahead of time, but the bao tang is incredible. They start cooking it about nine hours before it's served.
The only downside? Lei Garden has yet to open a branch in Puxi.