text:
Novel role of cPLA2α in membrane and actin dynamics
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DOI: 10.1007/s00018-010-0267-0
- Cite this article as:
- Moes, M., Boonstra, J. & Regan-Klapisz, E. Cell. Mol. Life Sci. (2010) 67: 1547. doi:10.1007/s00018-010-0267-0
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Actin-directed processes such as membrane ruffling and cell migration are regulated by specific signal transduction pathways that become activated by growth factor receptors. The same signaling pathways that lead to modifications in actin dynamics also activate cPLA2α. Moreover, arachidonic acid, the product of cPLA2α activity, is involved in regulation of actin dynamics. Therefore, it was investigated whether cPLA2α plays a role in actin dynamics, more specifically during growth factor-induced membrane ruffling and cell migration. Upon stimulation of ruffling and cell migration by growth factors, endogenous cPLA2α and its active phosphorylated form were shown to relocate at protrusions of the cell membrane involved in actin and membrane dynamics. Inhibition of cPLA2α activity with specific inhibitors blocked growth factor-induced membrane and actin dynamics, suggesting an important role for cPLA2α in these processes.
KeywordscPLA2α Actin Arachidonic acid Membrane dynamics Ruffles Lamellae Leading edge Migration
Phospholipase A2
- cPLA2α
Cytosolic PLA2 alpha
- HUVECs
Human umbilical vein endothelial cells
Actin plays an essential role in a wide variety of dynamic events in mammalian cells, amongst them cell motility, cytokinesis, and cell–cell and cell–matrix interactions [1, 2, 3, 4]. Actin dynamics are determined by the activities of a large number of actin-binding proteins. Extracellular stimuli, like growth factors and extracellular matrix components, stimulate intracellular signal transduction cascades that activate actin-binding proteins resulting in changes in local actin dynamics. These changes result in morphological changes like the formation of membrane ruffles and leading edges. In addition to changed actin dynamics upon growth factor addition or cell spreading, many signal transduction components are bound to actin, indicating the mutual relationship [5, 6, 7].
An important molecule involved in the regulation of cell metabolism is the unsaturated fatty acid arachidonic acid, which serves as a precursor for leukotriene and prostaglandin synthesis. However, arachidonic acid release has also been related to the regulation of actin dynamics [8]. In HeLa cells, an increase in arachidonic acid production was shown after cell attachment. This results in both actin polymerization and actin bundling via two distinct pathways involving lipoxygenase and cyclooxygenase [9, 10]. These enzymes metabolize arachidonic acid, resulting in the release of lipid second messengers that activate actin-binding proteins and consequently cause a change in actin dynamics. Additional to its role in cell spreading and immobilization, arachidonic acid was also shown to stimulate cell motility via the production of prostaglandins by cyclooxygenase. Prostaglandins play a role in actin cytoskeletal regulation and migration in a variety of ways. For example, stimulation of cells by chemokines resulted in an increase of prostaglandins and consequently in an increase of actin polymerization [11]. Moreover, several forms of stimulated migration require arachidonic acid metabolites [12, 13]. In addition, dissolution of adhesion structures like podosomes is dependent on the production of prostaglandins [14]. The role of arachidonic acid-mediated signaling in the regulation of small GTPases that modulate actin remodeling has been illustrated in several studies. In Swiss 3T3 fibroblasts, various leukotrienes induce stress fiber formation via a Rho-dependent process [15]. In Rat2 fibroblasts, arachidonic acid induces membrane ruffling and this is prevented when a dominant-negative mutant of Rac1 (Rac1N17) is expressed, indicating that Rac1 is activated downstream of arachidonic acid-mediated signaling [16]. Since Rac was also shown to act upstream of arachidonic acid release [15], it is possible that arachidonic acid and Rac1 act in a positive feedback loop.
The release of arachidonic acid in cells results from cleavage of membrane phospholipids at the sn-2 position by phospholipases A2 (PLA2). The large family of PLA2 consists of several sub-families like the secretory PLA2s (sPLA2), the intracellular calcium independent PLA2s (iPLA2), and the group of cytosolic PLA2s (cPLA2) including cPLA2α [17]. Interestingly, cPLA2α is highly specific for phospholipids carrying arachidonic acid at the sn-2 position and is therefore considered as the rate-limiting enzyme in receptor-mediated arachidonic acid release. cPLA2α requires Ca2+ to translocate from the cytosol to the membrane through its CaLB (calcium-lipid binding) domain, although Ca2+ is not directly involved in catalysis [18]. The activation of cPLA2α results from a phosphorylation by MAP kinase (for review, see [18]). This MAP kinase on its turn is activated by the same signal transduction cascades (growth factors and extracellular matrix components) that lead to modifications in actin dynamics. Therefore, it is tempting to suggest that cPLA2α is one of the key enzymes involved in local actin dynamics that are involved in the formation of membrane ruffles, and in cell motility.
Therefore, we have studied the localization of cPLA2α in fibroblasts during stimulation with platelet-derived growth factor (PDGF). Stimulation with PDGF introduces circular dorsal ruffles and lamellipodia. Here, we show that endogenous cPLA2α and its active, phosphorylated form are localized at the cell membrane in response to PDGF stimulation. They localize specifically to areas at the cell membrane that are reshaped by actin during PDGF stimulation. Furthermore, endogenous cPLA2α and its active phosphorylated form are shown to localize at leading edges in primary human umbilical vein endothelial cells (HUVECs) and migrating mouse fibroblasts. Interestingly, inhibition of cPLA2α activity with specific inhibitors blocked PDGF-induced membrane and actin dynamics, suggesting a role for cPLA2α in these processes.
Materials and methods
Cell culture
Human umbilical vein endothelial cells were isolated according to Jaffe [19] and used from passage 1 to 4. HUVECs were cultured onto fibronectin-coated surfaces and grown in endothelial basal medium (EBM-2) supplemented with 2% fetal bovine serum (FBS) (Gibco, Paisley, UK), endothelial cell growth supplements (EGM-2) (Cambrex, NJ, USA), and 5 mM l-glutamine (Invitrogen). C3H10T1/2 mouse fibroblasts were cultured in HEPES (25 mM) buffered Dulbecco's modified Eagle's medium (DMEM) (Gibco) supplemented with 7.5% FBS and 5 mM l-glutamine. Cells were grown at 37°C (humidified atmosphere, 5% CO2).
HUVECs were seeded on glass coverslips at 10,000 cells/cm2, coated with fibronectin and allowed to grow for 2 or more days to obtain sub-confluent monolayers for localization studies and confluent monolayers for the scratch assays.
Fibroblasts were plated on glass coverslips at 12,000 cells/cm2 and allowed to grow for 24 h. For PDGF stimulation experiments, cells were subsequently growth factor-starved for 24 h at 37°C and stimulated with 20 ng/ml of PDGF-BB (Upstate, Hampshire, UK). Treatment with cPLA2α inhibitors Pyrrolidine-2 (2 μM) and Wyeth-1 (5 μM) was performed in serum-free medium. Both inhibitors were kind gifts from Prof. Dr. M. Gelb (University of Washington, Seattle, USA).
Immunofluorescent labeling
Cells were fixed in 3.2% formaldehyde for 15 min, washed twice with PBS, permeabilized for 5 min in PBS containing 0.2% Triton X-100, followed by two washes in PBS, and incubated for 10 min with 50 mM glycine in PBS. After washing twice with PBS containing 0.2% gelatin, cells were incubated overnight with goat anti-cPLA2 (Santa Cruz; sc-1724) or for 1 h with rabbit anti-phospho-cPLA2 (ser505) (Santa Cruz; sc-34391). Then, the cells were washed six times with PBS containing 0.2% gelatin and incubated for 1 h with tetramethylrhodamine-5-(and-6)-isothiocyanate (TRITC)-conjugated phalloidin (Sigma) combined with goat-anti-rabbit-Alexa488 or donkey-anti-goat-Alexa488 (Molecular Probes) and washed six times PBS containing 0.2% gelatin. In some samples, this was followed by a DAPI staining for 10 min. Finally, cells were mounted in Mowiol-DABCO.
Transfections with GFP-cPLA2α were performed using Lipofectin (Invitrogen) according to the manufacturer's instructions. This construct, kindly provided by Dr. C. Lenoir (Inserm Unit 538, Paris, France), was checked by sequencing.
Scratch assay
HUVECs were seeded on fibronectin-coated glass coverslips at 10,000 cells/cm2 (~10–20% confluency) and allowed to grow for 7 days with regular change of medium. Cells were gently scratched from the substrate using a pipette tip. The remaining cells were washed with culture medium and allowed to reoccupy the wounded area for various time intervals. Mouse C3H10T1/2 fibroblasts were seeded at 20,000 cells/cm2 and allowed to grow to confluency before performing the scratch assay as described above.
Acquisition of images
Samples were studied with a Leitz microscope (Orthoplan Flu 043944) equipped with Leitz oil objectives ×40 NA 1.3 and ×63 NA 1.4. Images were acquired using a Leica CCD camera (model DC350F; Leica Microsystems) using Leica Image Manager 50 software. Confocal pictures were obtained using a Zeiss CLSM (Pascal 510) equipped with Zeiss water objectives (×40 NA 1.3 and ×63 NA 1.4). Images were processed with Adobe Photoshop 8.0.
cPLA2α is recruited to PDGF-induced dorsal membrane ruffles and lamellae in C3H10T1/2 fibroblasts
In addition to the formation of membrane ruffles, C3H10T1/2 cells also form lateral lamellae upon addition of PDGF (Fig. 1n). Whether the cells form lamellae or circular ruffles is determined by the PDGF concentration used. At concentrations >20 ng/ml, abundant circular ruffling takes place, whereas at concentrations in the range of 1–5 ng/ml, less circular dorsal ruffles occur and more lamellae are formed. The formation of lamellae is related to cell spreading and/or cell motility. As clearly shown in Fig. 1n, treatment of cells with 20 ng/ml PDGF for 10 min at 37°C results in the formation of lamellae characterized by a lateral band of newly formed F-actin (Fig. 1n) in which cPLA2α accumulates (Fig. 1m), while the perinuclear localization of cPLA2α, as observed in untreated cells (Fig. 1j), disappeared. Together these data clearly demonstrate that PDGF-induced actin remodeling is accompanied by a recruitment of cPLA2α to sites of new actin polymerization and membrane dynamics.
cPLA2α is localized at leading edges of migrating mouse fibroblasts
cPLA2α is localized at leading edges of migrating primary human endothelial cells
To determine whether the recruitment of cPLA2α at sites of actin polymerization as observed in fibroblasts is a conserved phenomenon, the relationship between cPLA2α and F-actin was studied in primary endothelial cells of human origin, i.e. HUVECs. It has been demonstrated that cPLA2α translocates to the Golgi complex in response to confluency in HUVECs [25, 26]. A scratch assay was performed on a confluent monolayer of HUVECs and the localization of cPLA2α and F-actin was examined. Immediately after scratch, cPLA2α was localized at the Golgi apparatus in all cells (lining the wound or not) (Fig. 2h). Four hours after the scratch, cells located at the border of the wound displayed protrusions of the plasma membrane in which cPLA2α was detected and where cPLA2α locally co-localized with F-actin (data not shown). Subsequently migrating cells reoccupy the wounded area. Twenty-two hours after scratch, migrating cells filled up the wounded area (Fig. 2j, k, l) and displayed cPLA2α staining at the cell membrane (Fig. 2k) and leading edge (Fig. 2k insert), where it locally colocalizes with F-actin. In contrast to confluent cells (Fig. 2h), in the wounded area, cPLA2α is localized primarily in the cytoplasm and also at the cell periphery (Fig. 2k). This latter localization may both be related to cell spreading and cell migration.
Phosphorylated cPLA2α is present in circular dorsal ruffles and leading edges
Inhibition of cPLA2α enzymatic activity prevents the formation of PDGF-induced circular ruffles and lamellae
Arachidonic acid release has been demonstrated to play a role in actin polymerization. Since activation of cPLA2α results in the preferential release of arachidonic acid, it is tempting to suggest that cPLA2α is a key enzyme involved in the regulation of local actin dynamics. Therefore, we have studied the localization of cPLA2α in fibroblasts and HUVECs in relation to induced actin dynamics. Endogenous cPLA2α was shown to localize at the plasma membrane in both migrating mouse fibroblasts and migrating HUVEC. Moreover, the phosphorylated form of cPLA2α (on Ser505) was found at the plasma membrane in both cell types. Both cPLA2α and phospho-S505-cPLA2α localize at protrusions of the cell membrane that show active actin and membrane remodeling such as circular dorsal ruffles, lamellipodia, and leading edges. Interfering with the activity of cPLA2α in mouse fibroblasts resulted in the blocking of PDGF-induced actin and membrane dynamics.
cPLA2α is present at the cell membrane in a spatio-temporal manner. Upon PDGF stimulation, cPLA2α docks at specific sites at the cell membrane, namely at lamellipodia and ruffles. Upon stimulation of migration, cPLA2α docks at the leading edge of motile cells. Also here, the localization of cPLA2α at the cell membrane is local and temporal. This indicates that its docking at the cell membrane is tightly regulated. It was suggested that cPLA2α interacts with membranes via PtdIns(4,5)P2. It was shown that PtdIns(4,5)P2 stimulates cPLA2α activity independent of calcium suggesting an interaction between PtdIns(4,5)P2 and cPLA2α allowing cPLA2α to reach its substrate at membranes [31]. PtdIns(4,5)P2 is primarily located in the cytoplasmic leaflet of the plasma membrane. Interestingly, it has been demonstrated that a variety of signal transduction proteins, including growth factor receptors, reside in areas of high actin polymerization, such as membrane ruffles [7]. Receptor activation can increase or decrease local PtdIns(4,5)P2 concentrations via the local activation of kinases and phosphatases like PI5K, phospholipase C, phospholipase D, and PI3K [32]. By doing so, receptor activation might also regulate the docking of cPLA2α at the cell membrane upon growth factor stimulation. Interestingly PtdIns(4,5)P2 was shown to be enriched locally at the leading edge [33] and phosphatidylinositide metabolism was shown to be involved in ruffle formation [34, 35, 36].
The local presence of cPLA2α and its phosphorylated active form at sites of actin and membrane remodeling indicates a role for cPLA2α in regulating membrane dynamics. This is also suggested by blocking of PDGF-induced actin and membrane dynamics after exposure to the cPLA2α inhibitors Pyrrolidine-2 and Wyeth-1. Of note, these inhibitors also block the enzymatic activity of another cPLA2 from group IV, namely cPLA2ζ [30]. This enzyme can release arachidonic acid from membrane phospholipids but, contrary to cPLA2α, it does not have specificity for arachidonic acid versus other fatty acids [30]. However, in C3H10T1/2, cPLA2ζ is not expressed, as confirmed by RT-PCR (our unpublished data). This observation strengthens our inhibitors-based results, reinforcing the idea that cPLA2α plays a major role in regulating actin dynamics.
The local presence of the active form of cPLA2α might indicate a local production of arachidonic acid by cPLA2α. Subsequently, arachidonic acid might affect locally the behavior of actin via arachidonic metabolites. Arachidonic acid release has been previously related to the behavior of actin. During cell spreading, actin is changing the cytoskeleton and thereby changing the cell morphology. In HeLa cells, an increase in arachidonic acid production was shown after cell attachment. This results in both actin polymerization and actin bundling via two distinct pathways involving lipoxygenase and cyclooxygenase [9, 10]. Lipoxygenase metabolizes arachidonic acid and via a cascade of lipid second messengers protein kinase C epsilon (PKCε) is subsequently activated which triggers actin polymerization leading to cell spreading. Cyclooxygenase generates prostaglandins resulting in the activation of cyclic AMP-dependent protein kinase A (PKA) that induces actin bundling. Moreover, PKA was shown to play a role in the actin cytoskeleton regulation in a variety of ways (for review, see [37]). So, an increase of arachidonic acid causes an increase in actin polymerization and bundling during cell spreading by activating actin-binding proteins like PKA and PKCε. Furthermore, arachidonic acid and some of its metabolites can activate signaling pathways leading to the activation of small GTPases such as Rac1 and Rho [15, 16], ultimately resulting in actin remodeling. It has long been known that arachidonic acid and some of its metabolites can bind directly to and regulate the activity of specific GTPase-activating proteins (GAPs), which are regulators of small GTPases [38, 39]. Altogether, it is tempting to suggest that the local production of arachidonic acid and of its metabolites could trigger signaling pathways resulting in the local remodeling of actin.
In addition, cPLA2α is able to change the local characteristics of the plasma membrane by interacting with membrane phospholipids. cPLA2α-mediated hydrolysis of cellular membranes results in the production of lysophospholipids within the lipid bilayer and the lysophospholipids thus produced change the plasma membrane microviscosity. A change in the plasma membrane microviscosity by lysophospholipids was shown to affect cell migration [40]. Plasma membrane microviscosity has an important role on actin dynamics and thereby regulates cell motility [40, 41]. It was suggested that an increase in the plasma membrane microviscosity in lamellipodia might result in a local increase of actin-directed movement [41]. Our results show active cPLA2α at sites of active actin remodeling, and cPLA2α might here locally direct the behavior of actin by changing the plasma membrane microviscosity.
Altogether, our data show that cPLA2α is specifically recruited at sites of actin and membrane remodeling in different cellular processes. Since this phenomenon occurs in mouse fibroblasts and in primary human endothelial cells, it is likely to represent a general property of cPLA2α. However, further research is required to fully elucidate the role of cPLA2α in the above-mentioned processes.
We like to thank Prof. M. Gelb for supplying the cPLA2α inhibitors. We thank C. Lenoir for supplying the GFP-cPLA2α constructs. We thank Bart de Haan and Miriam Langelaar-Makkinje for isolating HUVECs. We thank José Bijvelt and Mohammed El Khattabi for their help with the RT–PCR of cPLA2α and cPLA2ζ. This work is subsidized by the Dutch Space Organization (SRON, grant MG-059).
Open Access
This article is distributed under the terms of the Creative Commons Attribution Noncommercial License which permits any noncommercial use, distribution, and reproduction in any medium, provided the original author(s) and source are credited.


text:
Have I missed something? Hard vs Softsub
I haven't been involved in any projects for quite awhile now, but last I knew the general feeling on softsubs was "lol, softsubs" or people were neutral on it. Some liking it bc they could set their own fonts if they wanted to.
So I use hardsubs like I have for everything since 2001, and suddenly I'm getting hated on for not using softsubs now, or they "hate the font" etc. (Even though it's a very readable sans-serif font in plain black and white)
More than anything I guess I just dislike the prospects of script-stealing groups. If they want to ask me for permission to use the TL for another language sub, I'd probably be willing to agree. It's the stealing without ever asking or thanking that unnerves me.
I don't really know why some really edgy about others getting their script to use in another language/format. If I'm subbing because I want to help anime fans to enjoy them, why would I care for credits or "thank you" notes!
Hardsubs make it easier to upload to youtube, so you have to decide if that or the prospect of someone else stealing your subs - which they can anyway - is worse.
I look at it this way: softsub is a biproduct of h.264. They're not related, but they are.
When people started making h.264 releases, they had to do the right thing and use mkv container. And when they used mkv container, they had to do the right thing and use the softsub. As such, softsub became a part of higher quality package.
And then, there also was a very vocal advocate of softsubs right when this transition started to happen.
Also, as it was already mentioned, reasons to stick with hardsub such as "so it won't be stolen" is now laughed at. "It's so easy to steal anyway." "You stole the anime from the producers, but you don't want your subs to be stolen? You hypocrite." etc...
And thus the one-sided holy war continues.
My opinion is: Softsubs are crap.
I hate them, hardsubs all the way! Yaay~!
Why all the hate on softsubs? It's basically the same as hardsubs, but you have the option to remove them. If subs are stolen they can also be stolen from hardsubs its just that it takes a little more time(A whopping 30mins more?).
Lets not talk about streaming sites. Since a little bit of rendering will get you the softsubs on them too. But streams are shitty how so I don't know why there is even a debate about that... >_>
Not that I dislike hardsubs in anyway, but why the hate on softsubs? Since softsubs are superior to hardsubs. o_O
I'm not hating on softsubs. I'm hating on people hating on hardsubs. :)
But you are right I guess when it comes down to it we're splitting hairs about the work to animate the show vs the work to subtitle the show.
If they want to steal the hardsubs then they have to spend the time sitting there writing the script down, still time the episode themselves, etc. Instead of clicking 1 button to strip the file from the MKV and slap it on theirs.
Fansubbing has its roots in the grey where, yeah you're taking anime, but we still have a list of rules/ethics that are followed. So if they're not even willing to ask for the translation, I don't see why I should make it easy for them.
Glances over at sourceforge.net .... <sigh> pros and cons... I just prefer people credit their reference materials.
But you're right about the softsubs -- VLC handles softsubs like crap. Using CCCP with Media player classic at least renders them properly and then you really can't tell a difference from normal hardsubs.
I'll consider the softsubs, I'm still trying to catch up after having been out of the loop skills-wise for over 2 years now.
The appeal of hardsubs for me, anyway, is that as the encoder, you know what the finished product will look like. Softsubs still have too many inconsistencies in playback across multiple platforms.
Other than that, softsubs are great and we do use them for a number of our group's releases.
BTW, Jedi, come onto irc, we'll catch up on old times :)
Two years or so ago I hypothesized about new ways to make subs harder to steal. It was a combination of both hardsub and softsub playback, splitting sentences into two different scripts with missing complementing characters and using ASS pixel spacing to visually place them back to a whole during playback. But my evul dreams were instantly shattered when I figured out you can load .avs files and OCR from there. ;_____________;
^ That's really clever
As a leecher, I have no right in being choosy. However, I do have a preference for softsubs, since I could make animated GIFs and stuff of the like without having words at the bottom.
as i've said before, the main reason softsubs are attractive is the flexibility.
no more reencoding for each damn small error found in an RC, etc
and obviously, multiple stream capacity.
i personally hate notes, that is, when groups abuse them (which nearly every group ever does). when i had to put in notes to explain some stuff, i would just create 2 sub streams: one with notes and one without notes.
anyhow, softsubs are more flexible and easier to use. even tho i don't really care about hardsubbing, i really can't imagine why fansubbers don't make more use of softsubbing.
Lol @ xris. Really though, getfresh's troll thread on this exact subject eventually had plenty of useful information. You shouldn't have nuked the entire thing.
You can't just say "well if there are no rational reasons I'll be irrational!". Doing that just makes you Wrong -- and I don't mean wrong in any sort of poor-persecuted-peoples sort of way, I just mean fruity-loop-reality-ignorer wrong.
That being said, I'd go with softsubs because I don't need to use my machine for reencoding raws. :D But I really don't care as long as I'm not the one encoding.
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A Lesson
There's a lesson I've learnt over the years,
It's simple, really. You have to know.
Just a few words that can change everything,
A message to be heard through sun and snow.
It goes like this.
Never let people make decisions for you,
Never let them change your mind,
If you think you can do it, it's true,
Don't leave your dreams behind.
Be optimistic when things are tough,
Remember your passion every day,
Don't take the offer of an easier option.
Keep the pressure so far away.
Take your time in making choices,
Do what's going to be best for you,
Consider what makes you happy,
Sometimes you have to be selfish too.
Because sometimes easy isn't satisfying,
And giving up can be the end,
Advice doesn't have to be readily taken,
It's only an opinion of a person's to lend.
Deep in your heart there's always an answer,
Your mind doesn't always speak what's true,
Be yourself, don't ever change that
And follow the direction that's right for you.


text:
Fort Ranik (Pre-Searing)
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|Fort Ranik (Pre-Searing)
|Basic Info
|Regent Valley (Pre-Searing)
Used as a training facility for the Ascalon army, Fort Ranik houses new recruits. Here, soldiers learn what it takes to be one of Ascalon's finest and bravest, and how to use their talents to defeat the enemy. Fort Ranik is one of the best-equipped strongholds in the kingdom.
Getting there
Travel southeast from Ashford Abbey through Lakeside County and Regent Valley.
- Regent Valley (south)
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2012-13 Ratings discussions
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Location: Ottawa
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Just looked over the ratings and 2 guys that stood out for me were Garnett Exelby and Ryan Potulny... for as little games they have played in the NHL in the past 2 seasons, they seem to have rather high ratings - can anyone explain?
Ville actually mentioned these two guys in an e-mail discussion amongst the ratings group, and they are good catches.
The reason their ratings are still NHL-fringe worthy, is their last 82 games were pulled from the last 3 NHL seasons. Typically for players with low games played (<100), the games were in the more recent seasons. For Potulny and Exelby, the majority of the games (or all, in Exelby's case) were from the 09-10' season.
Now because we take the last 82 games (or 164), a guy has played during the three years, a guy like Potulny is still a 15 goal scorer, because even with his 0 points in 10 NHL games over the last two years, the weight of his 15 goals in 65 games or whatever it was in Edmonton, still drive the bulk of the weight of his rating. That said, his rating was reduced (as were all players) with fewer than 82 games over 3 years, so his rating is still lower than in past.
That said, this type of scenario probably justifies a bigger penalty or reduction, but there are only a few players who fall into this category, and given they are marginally rated anyway, we're likely to adjust the rating formula next year rather than try and go back and change it to account for just a few players like this.
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Guts , Glory and Pride
Book by: Snyder
Status: Finished
Genre: Other
Chapter1 (v.1) - Guts , Glory and Pride
Guts, Glory and Pride
Sam awoke abruptly as the song sweet home Alabama chimed merrily in rhythm through the morning. He looked at his clock while wiping the sleep from his eyes. "Seven", he thought to himself .Turning off the alarm Sam moved to his dresser in a sleepy haze. Pulling on his clothes Sam started downstairs and then quickly retraced his steps remembering that he had forgotten his math book. As he hit the bottom steps and was just about out the door he heard his mother call, "Sam come get your breakfast".
He moved back towards the kitchen and the sweet aroma of hash browns and sausage links filled the air. His mother handed him a plate and said, "Dig in". After gobbling down a good sized portion Sam took off out the door and got in his car and started driving towards school. About three blocks into the journey Sam's cell phone started to vibrate and Sam looked down at a name. It was Vanessa.Using one hand Sam flipped his phone open and said, "Hey what's up?" "Hey Sam, was just wondering if you could pick me up this morning my dad just left for work", said Vanessa.
"Sure I'll be right over, Sam replied. Ever since they were little Sam found himself constantly helping Vanessa and looked at her almost as if she were his own sister. When he arrived at Vanessa's house he got out of his car and went up and knocked on the thick oak of the front door. The door swung open revealing Vanessa still brushing her hair. "Come in", she said. Sam had been in the house many times before as Vanessa's parents and Sam's parents played Scrabble every Saturday night. Sam sat in a big lazy boy sofa positioned in front of the television.
As Vanessa moved about frantically grabbing a book there or a paper on a self all while still fussing with her dark brown hair. She said to Sam,"So do you think that you're ready for your final football season Sam?" Sam replied, "Yeah, this is my last year and I want to impress someone so I can maybe play in college." "I know that we can win if we set our minds to it." Vanessa replied, "Well dad seems to think that this will be the best team that our school has seen in a long time." "Especially from watching that scrimmage last week"
"You should hear him talk about you Sam he just laps you up the way a dog drinks water." Sam's face flushed. "I just try to do what any other guy would do if they were the quarterback", he replied. Glancing in the mirror and finally seeming satisfied with her hair, Vanessa said, "We better hurry or we'll be late". Getting out of the chair Sam moved towards the door and as Vanessa brushed past him he caught a whiff of some tropical smelling soaps and a heavy scent of raspberry perfume.
Getting a good look at her as she walked out the door ,Sam realized that Vanessa was becoming a very attractive woman. She was now at least five foot – eight inches tall and her curves were now fully defined. At school Vanessa was a very popular girl and it was not hard to see why. Vanessa turned and looked toward Sam with a look of puzzlement and said, "What?"
"Nothing", Sam replied.
They climbed into Sam's car and headed toward school. Upon arriving Vanessa got out of the car and said, "See you after practice Sam." Sam was barely able to get off an ok as Vanessa had already spotted her friends and took off in their direction. Sam got out of the car and started walking toward the gym side entrance to the school.
The smell of fresh cut grass filled Sam's nostrils and the sun beamed brightly off the towering yellow goal posts. "For weeks we've been practicing and now this week we finally get to play," Sam thought. He opened the door and walked through the door in realization that the final year had just begun.
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Turn its frown upside down: fill it with gifts
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Pamper her with the perfectly pink perfection with ferns n petals. Get her a gift hamper of Maybelline New York Color Show Coral Crazy Nail Lacquer along with Color Me perfume and Nivea Soft Rose Lip Balm Stick in a jute basket. Make her flaunt her feminineness to the world with this perfect gift set.
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Store the items in a cool, dry place. Please refer to the expiration date on the package of your cosmetics and use them before that.


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Sagging skin makes you look older, which is why it's so coveted by teenagers. Look youthful with this Groupon.
Choose Between Two Options
- $79 for one photo-rejuvenation facial and one nonsurgical microcurrent face lift (up to a $479 value)
- $69 for one blue-light acne treatment with an acne-fighting face mask (up to a $379 value)
Using red light light, the photorejuvenation treatment lessens signs of aging, such as fine lines and wrinkles. The light breaks up the unwanted pigment, causing it to fade into the body. For some people, it may be uncomfortable and possibly painful. The microcurrent facelift uses gentle electric currents to tighten facial muscles and sagging skin.
The blue-light acne therapy gently permeates the skin's surface to destroy acne-causing bacteria. An acne-fighting mask helps further clear up skin.
iSlimQuick Laser Spa
A 16-paddle laser light traverses the skin's surface, penetrating fat cells in order to prompt them to release their contents. iSlimQuick Laser Spa's iSlim lipo procedure is designed to smooth the appearance of cellulite and tighten skin without needles or post-procedure downtime. All this happens as the client reclines comfortably and listens to relaxing music. They can also increase results after treatments by working out or moving all of a caveman's rocks around as a joke.
Customer Reviews
3115 Piedmont Rd.
Suite 101
Atlanta, GA 30305
+14048554644Get Directions


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On Tuesday (28 April) the European Parliament voted on a multiannual plan for managing cod, sprat and herring stocks in the Baltic Sea.
MEPs want fishing quotas in the Baltic to stay below the maximum sustainable yield (F-MSY). This would allow fish stocks to grow to abundant levels, larger than biomass levels that can produce MSY catches in the long term, reflecting article 2 of the new common fisheries policy regulation.
The Council, however, last week adopted a position which would allow quotas to exceed MSY levels.
Parliament and Council negotiators will now start talks to reach a common agreement on the plan.
« The plan is a long-awaited pioneer proposal. It should help to ensure the balanced, sustainable exploitation of the stocks concerned and hence protect the livelihoods of fishermen. The multispecies approach should achieve this far more effectively than single species management. At the same time, the plan should also ensure that management measures reflect the most up-to-date scientific advice on stock status, interactions between species and ecological needs, said rapporteur Jarosław Wałęsa (EPP, PL) in a press release.
Read more:
– Find the documents through Legislative Observatory
– MEPs vote for sustainable fishing in the Baltic Sea (Parliament press release)
– EU citizens' representatives endorse a sustainable future for the Baltic Sea (Oceana press release)
Axel Naver


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Hotel Anjo Azul
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TravelPod Member ReviewsHotel Anjo Azul Lisbon
We kind of stumbled across this hotel after happily staying in a youth hostel but desiring a double (instead of a tiny twin) bed. The price was fair, $40eu for two. Private bath, and surprise to us private patio (with no view). This hotel is in the heart of the Bairro Alto district. Literally, blocks from the "view point" and art / night life / restaurant district. Best of all, they had no problem storing our bikes for 3 nights right in the front lobby...the staff was beyond nice (spoke English) and respectfully kept our room very tidy. The night receptionist was an older man...so kind, fun...we would recommend and stay here again.
This review is the subjective opinion of a TravelPod member and not of TravelPod.com.
TripAdvisor Reviews Hotel Anjo Azul Lisbon
Travel Blogs from Lisbon
... interesting few minutes when we met up with a tram coming down a narrow single track section which had ignored the lights and couldn't reverse, so we and the tram behind us had to back up quite a way so the other one could pass us and we could continue! We got off the tram at Largo Das Portas do Sol where we could look down from the belvedere over the old Alfama area to the river. Then we wandered off to visit the church and monastery of San Vicente, after sidetracking a ...
Beer, pick pockets, and embarrassing moments
Leg 3 has taken quite some adjusting. From rising at 3am in to pulling up the covers in Lisboa, was 23 hours! Flights and taxi transport totalled 6 hours. ... the rest was waiting, waiting, waiting.
Dead by the time we arrived, dragging bags up to level 3 (fortunately we could bring the suitcases up in a tiny elevator) to our little 4-bed room. Maddi choose the bed in what looked like a converted balcony, but still opened to the rest of the room, then 3 more ...
Oct. 13: Lisboa (old town & the Castelo S. Jorge)
... about the sea or the life of the poor, and infused with a characteristic sentiment of resignation, fatefulness and melancholia (loosely captured by the word saudade, or "longing"). However, although the origins are difficult to trace, today fado is regarded, by many, as simply a form of song which can be about anything, but must follow a certain structure. The music is usually linked to the Portuguese word saudade which symbolizes the feeling of ...
Bloody Politics
... the welfare state and society could once again be restored. Apparently it did not work in either favor therefore it will be ending next week, and the people are rejoicing.
Now I, being the unseasoned politician, do not know what exactly to make of this seminar of Portuguese politics, but I do know the people that sit before me are learning a great deal to become the future politicians or aid in the teachings of the new politicians in Portugal. They ...
To go where no man has gone before!
... tap-highlight-color: rgba(26, 26, 26, 0.296875); -webkit-composition-fill-color: rgba(175, 192, 227, 0.230469); -webkit-composition-frame-color: rgba(77, 128, 180, 0.230469); -webkit-text-size-adjust: auto; ">The monastery was one of the few buildings to come out of the 1755 earthquake relatively unscathed - must have been all those prayers. Monks prayed for four centuries in this monastery; unfortunately their prayers did not stop Vasco da Gama ...


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Mountain Hardwear Ultralamina 32 Sleeping Bag - Women's - 2012 Closeout - $94.73
The Mountain Hardwear Ultralamina 32degF women's sleeping bag uses synthetic insulation with a welded construction to create a warm, light bag perfect for chilly, damp nights on backpacking trips. Mountain Hardwear women-specific bags are cut specifically for a woman's physique, and provide extra insulation and warmth in the hood and feet areas. Performance mummy cut features a snug overall fit that positions the insulation close to the body, maximizing warmth and minimizing weight without restrictiveness. Welded construction eliminates moisture entry points. Soft, durable and compressible synthetic insulation retains its loft and traps body heat to keep you warm; insulation continues to warm even when wet. Dual, 2-way zippers with locking sliders are backed by wide, antisnag binding tape; insulated zipper gusset seals in warmth at base of zipper. Insulated draft tube extends to bottom of bag to eliminate cold spots. Face gasket and tailored hood seal out cold air. Footbox is shaped to allow feet to rest naturally; shape preserves loft and allows insulation to drape close to feet for more warmth. Interior zippered pocket at shoulder stows small necessities such as your watch or lip balm. The Mountain Hardwear Ultralamina 32degF women's sleeping bag comes with a nylon compression stuff sack and a mesh storage bag. Closeout. - $94.73


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60 Ways To Make Your Marriage Rock8:00 PM
I found this list on someone's Facebook Page and started reading it for entertainment. And then a light bulb went on in my head and I decided to be a little snarky and see how I instantly reacted to each of these awesome (?) tips!
1. Always love each other, even when it's hard to
Bull shit. I would say always respect each other even when its hard to love
Again, bull shit! Just go to bed. Sleep solves everything.
This I agree. Wholeheartedly!
Do that. But let it not be a bit 'too' secret place :P
O! Dr. Fab is gonna love this one. He supports this 100 %. I believe sleep whenever you are sleepy!
Its not that romantic. Rather quite uncomfortable. Just get your own iPod & headset.
Yeah! Can't argue with that much. Can I?
8. Revitalize the romance with intimate dates
Didn't we already cover that in #3?
Huh? Let's NOT tell the world anything. Keep your love between yourself.
Sure. If its about something special. Else its just nauseating.
What on earth is that?!?!
I'd have to give in to this one. They are rather comfortable.
Yes! Privately being the most important part.
Yes! But not for your monthly anniversaries. Only when you cross the 25 year threshold.
I'd say more than once a year.
O.K. then! ;)
Alright, but I don't see how it would make my marriage rock?
Sure. Why not. If you are in the mood of baking!
Erm! Nothing sarcastic to say on this topic.
21. Surprise each other
Depends. But I would have to agree.
Can be cute! But not when you are sitting with other people. That's rude.
Huh? You mean you could actually forget you are married? Ever?
I wouldn't do that. But wait. Let me try. He doesn't know about this post ... He replied, "Why?"
26. Leave work on time and come home early
Wouldn't he have to leave work early to come home early?
What if you are a goofy-couple? Do you still 'have' to do that?
Sure. Only when you mean it.
30. Argue fair: avoid these words "you always" and "you never"
33. Forgive quickly
34. Be honest.
35. Get on the same page: plan your budget together
36. Look your best as often as you can
37. Guard your marriage
38. Laugh together
39. When you are together-BE TOGETHER (take a break from phones, technology, etc)
That would be the kind thing to do!
#1 - #15 were for ...?!?!?
42. Do each other's chores
44. Get a couple's massage or host your own privately
44. Dance together to soft music
45. Exercise together - hikes, bike riding, etc
Whenever time permits do it together. But exercise, regardless.
46. Choose not to be annoyed by an irritating behavior/disappointment from your spouse
We can 'choose' all we want, but it ain't gonna happen! :P
47. Thank your spouse often even for the least reason or gesture
That's right. Its also good manners.
48. Lay in bed together and stare into each other eyes, without talking
You are kidding right? I'd rather get to me long to-do-list which I never finish
49. Learn something new together-take an art class, cooking lessons, etc
Its fun to do activities together.
50. Leave a sweet comment on the Facebook wall
For the love of God, DON'T! Once in a while (read: max. twice a year), go for it. Anything more: Please Stop!
51. Support each other's goals
Damn right!
52. Bring her flowers/gifts (even when she says they are too expensive)
In my case, my husband knows I am not a big fan of flowers. They die. And I prefer to buy my own gifts.
53. Wear something your spouse loves
Sure. If you feel good in it as well.
54. Share furniture - sit in his lap
Just make sure you weight less than him!
55. Fight for your marriage
... with whom?
56. Make a point to eat dinner together most days of the week.
We prefer to eat breakfast and desserts together.
57. Never let your spouse feel like they come second place to your career or any other thing.
Hopefully both of you would be mature enough to realize that on different days, everyone has different priorities.
58. Talk about your dreams and aspirations. Be supportive of each other and dream big together!
Shut the F'Up! Be yourself and talk whatever the heck you want to.
59. Maintain a united front as your motto: Meaning- "Me and you against the world."
... and what if the world is not against us? :P
60. Speak well of your spouse.
1 comments
Most of the marriages fail due to some unreasonable disputes or extramarital relationships. It is certainly going to be intolerably painful for anyone to accept indifferent attitude of the life partner, instead of loving and caring relationship. Therefore, it will be extremely necessary to try rekindling the love bonds with your spouse, and stay happy forever.ReplyDelete


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Childspace Early Learning Centre
Contact: 04 461 7081
45 Helston Road, Johnsonville, Wellington 6037
At Childspace we believe that each child is unique and must be treated with acceptance and respect in order to develop to their full potential.Childspace has five childcare centres in Wellington, catering for children from four months to five years of age. Our childcare centres are villas and houses located throughout Wellington that have been converted to accommodate groups of children. This ensures a cosy and nurturing environment for children who spend time outside of their own homes. All our childcare centres are unique, and run under their own teaching philosophies. Each day is facilitated by the teaching teams who create quality programmes that are safe, stimulating, fun and nurturing environments for children of all ages. Our teams are passionate about the potential of each child and support the values of individual families. Each centre is led by a manager and supported by the principal. Together they oversee the educational programmes and personnel within each teaching team. All our childcare centres are located in Wellington and operate from 7:30am to 6:00pm Monday to Friday.
Click 'Visit Website' for more information.
- Childspace Ngaio Infants & Toddlers - 9 Tarikaka Street Ngaio Wellington
- Childspace Ngaio 2-5's - 11 Tarikaka Street Ngaio Wellington
- Childspace Wilton - 213 Wilton Road Wilton Wellington
- Childspace Northland - 17 Albermarle Road Northland Wellington
- Childspace Karori - 81 Old Karori Road Karori Wellington
Childspace Early Learning Centre
Contact: 04 461 7081
Contact: 04 461 7081
45 Helston Road, Johnsonville, Wellington 6037
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ED Magedson – Founder
Ripoff Report
BP Gas Station And Service Center,405 Waller Avenue Lexington, Kentucky U.S.A.
Does your business have a bad reputation?
Fix it the right way.
Corporate Advocacy Program™
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Steel boned underwire corset with front zipper closure, lace-up back for cinching, privacy panel in the back, and matching thong.
You're reviewing: BLUE STEEL BONED VELVET & BROCADE CORSET
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The Book of the Secrets of Enoch
€ 12,99
Lieferbar innert 2 Wochen
Juli 1999
BeschreibungTranslated from the Slavonic by W.R. Morfill. Edited, with Introduction and Notes by R.H. Charles For 1200 years this book was known only to a few people in Russia. When it was finally revealed to the world in 1892, it was announced that it was a Slavonic version of The Book of Enoch. This was wrong, Once translated, it was found that we have an entirely different book on and about Enoch, described, by the editor, as having no less value than the other book. This is a completely new and valuable pseudoepigraph, one which every person should read who is interested in Apocalyptic literature and the origins of Christianity. This particular book was read extensively by many separate Christian groups during the first three centuries, and it has left us today with many traces of its influence. It is now time to bring this book back into print so we may relearn its value to the world. This work was written in Egypt and we have determined that its author or original editor was a Hellenistic Jew. The Greek original has been lost to history, but the Slavonic text somehow survived. In its original Greek form it had a direct influence on the writers of the New Testament. This book was also referred to by Origen and used by the Church father, Irenaeus. It was read by, and considered valuable, by the heretics of the day in addition to mainstream Christians. This may be one reason why it was excluded from the Bible. We do not believe in banning or keeping hidden important works that have proven to be of such value in the past. We hope this book will enlighten and inform those who are seeking the truth.
Untertitel: Sprache: Englisch.
Verlag: BOOK TREE
Erscheinungsdatum: Juli 1999
Seitenanzahl: 148 Seiten
Übersetzer/Sprecher: Übersetzt von W. R. Morfill
Format: kartoniert


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Christina Shoben MBACP Reg
02088 159207 / 07711077424
About me
I am a qualified psychodynamic, person centred, cognitive, mindful CBT and Gestalt therapist, BACPregistered. I also work as a life coach.
I work with anxiety, fear, depression, self abuse and abusive relationships, eating disorder, bereavement, communication problems, stress, anger and trauma.
I come from a diverse, multicultural background. I have worked as a qualified counsellor for 18 years with people with learning difficulties, people with Aspergers and mental health issues, vulnerable children, young adults and families, couples, both one- to- one and in group sessions.
I worked as a counsellor with alcaholics, homeless and drug addicts and ex-offenders, with people from differing cultures and backgrounds. I have also worked with child abuse victims.
I have had a private practice for six years and have worked with local authorities.
Our journey in life becomes marked with our experiences. In protecting ourselves, we cause ourselves damage because we are unable to see the whole picture. Signals get misinterpreted as we grow up and damage continues to follow. I help you to recognize where everything starts and help you to move on, feeling empowered and self accepting.
As a Member of the British Association of Counsellors and Psychotherapists I work within their Ethical Framework of good practice which is safe and confidential and which you can look up on www.bacp.co.uk. I am committed to on-going professional development to enhance my work.
Training, qualifications & experience
I am a BACP registered Counsellor and Life Coach.
I am very experienced and have taken a number of post graduate courses and seminars for my on-going professional development such as:
- Behavioural
- CBT (Cognitive Behavioural)
- Family therapy
- Gestalt
- Humanistic
- Integrative
- Person Centred
- Play Therapy
- Psychodynamic
- Solution Focused Brief Therapy
- Raising awareness of Asperger's Syndrome
- Working with Anxiety using CBT
Areas of counselling I deal with
- Abuse
- Addiction(s)
- Affairs and betrayals
- Alcoholism
- Anger management
- Anxiety
- Asperger's syndrome
- Attachment disorder
- Bereavement
- Bullying
- Cancer
- Career
- Carer support
- Child related issues
- Disabilities
- Dissociation
- Domestic violence
- Drug abuse
- Emotional abuse
- Family issues
- Gambling
- Generalised anxiety disorder
- Hearing voices
- Learning difficulties
- Low self-confidence
- Low self-esteem
- Panic disorder
- Passive aggressive behaviour
- Personality disorders
Therapies offered
- Acceptance and commitment therapy (ACT)
- Behavioural therapy
- Cognitive analytic therapy (CAT)
- Cognitive and behavioural therapies
- Cognitive behavioural therapy (CBT)
- Cognitive therapy
Counselling: £45; Life Coaching £50; concessions
Please email me on: email@example.com
or contact me by text or phone on: 07711 077424
Further information
My counselling usually takes place in Muswell Hill, London N10 or in home visits in and around North London.
Maps & Directions
Type of session
|Online counselling:
|Telephone counselling:
|Face to face counselling:
Practical details
|Sign language:
|Other languages:
9am to 8pm.
Types of client
|Young people
|Older adults


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Mads Norgaard Kids. Dark blue fine knitted cotton dress with red striped pattern, long sleeves and round neckline. True to size.
Orangebag-number: S461451
Fabric: 100% cotton.
30C machine wash
Orangebag-number: S461451
Style: 60547 Bretagne Ringel Dilika / 657 Navy-Red
* Free, insured shipping (>EUR 75) to NL, BE and DE.
* Free return service from NL, BE and DE for an exchange; EUR 3.95 without an exchange.
* Next day delivery on orders made on business days before 16:00 hrs. (Germany 14:00 hrs.)
* Insured shipping NL and BE: PostNL, no neighbour delivery or PostNL Pakjegemak
* Insured Shipping to and from Germany with DHL./ Deutsche Post
* Free shipping on exchange orders EUR 75 and up (all Countries)
* Easy online exchange without payment (also with refund)
* Refunds paid within 3 business days .


text:
As noted by VentureBeat, EA revealed today during its earnings call with investors that for the first time, Apple has become "EA's biggest retail partner as measured by sales" as a result of the App Store. It's a big announcement for the publisher that previously sold the majority of its content through retail channels for console games, and it could be a sign that EA will be investing more in iOS and other mobile titles in the months to come. In its earnings release, the company noted that it was "the #1 global publisher in the iOS game market in the June quarter," and also highlighted a few of its more successful iOS titles, including: The Simpsons: Tapped Out, Real Racing 3, and The Sims: expand full story
Q1 Stories July 24, 2013
Q1 Stories May 16, 2013
Research firm IDC is out with its latest numbers for Q1 2013 today tracking worldwide smartphone shipments by OS and OEM noting Android and iOS combined accounted for 92.3% of all shipments during the quarter.
IDC noted that Apple and Android shipments combined increased year over year approximately 59.1% with a total of 199.5 million units shipped worldwide during Q1. That's up from just 125.4 million a year ago. Apple is clearly a large driver of the growth with the report pointing out that iPhone had its "largest ever first quarter volume." However, despite that, Apple also saw a decline among usage of iOS compared to growth of the industry as a whole, allowing Android to keep its top spot by OS and Samsung to remain number 1 by OEM.
How far is iOS behind Android? According to IDC it accounted for 17.3% of the market in Q1 compared to 75% for Android. Of course this is likely taking shipments (not sales) into account and also doesn't represent tablet usage that we know iOS continues to dominate. expand full story
Q1 Stories May 16, 2012
Q1 Stories May 1, 2012
Following IDC's report this morning that highlighted Apple's continued growth among mobile phone marketshare worldwide, while coming second to Samsung in global smartphone marketshare, research firm comScore just released its numbers for United States mobile subscribers for the three-month period ending March 2012.
According to comScore, Apple posted impressive growth during the quarter with 30.7-percent marketshare among smartphone platforms in the U.S (up from 29.6-percent). Increasing from 47.3-percent in December 2011 to 51 percent in March 2012, Android was able to grab the top position for platforms during the quarter. Growth for Android and iOS continues to come at the expense of RIM. The company grabbed just 12.3-percent of the platform market in March, which is down from 16 percent in December 2011. Microsoft also lost marketshare with 3.9-percent, which is down from 4.7-percent… expand full story
Q1 Stories April 3, 2012
Following Nielsen's latest survey that showed over 90 percent of United States smartphone buyers are choosing iOS or Android, research firm comScore today released its data of the top smartphone platforms and OEMs in the U.S. The survey included more than 30,000 people over a three-month period ending February 2012. It found Android was up 17 percentage points from a year ago with 50.1-percent of the U.S. smartphone market. In comparison, Apple's 30.2-percent accounted for an increase of 5 percentage points from the same period a year ago.
According to comScore, Google passed the 50 percent milestone for the first time during February 2012. The numbers represent a 3.2-percentage point increase over previous three-month period for Google, and a 1.5-percentage point increase for Apple.
Q1 Stories January 23, 2012
Apple will report its fiscal first quarter results tomorrow for the October to December 2011 period during which the Cupertino, Calif.-based company saw the death of its cofounder and the record-breaking sales of its latest iPhone.
Apple passed the $400 billion market cap briefly last week, and it is the world's second most valuable company after Exxon Mobil Corp. Its 2007-debut of the iPhone effectively piloted the touchscreen smartphone market, meanwhile the iPad carved a new consumer electronics category for the industry, as well.
Analysts expect earnings of $10.04 per share and revenue of $38.92 billion, according to FactSet, compared to Q1 FY11 where Apple earned $6.43 per share on $26.74 billion in revenue. Apple said it reckons earnings of $9.30 per share and revenue of $37 billion for Q1 FY12, but the technology giant usually underestimates its forecasts, and analysts generally ignore such predictions…


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Turlock Youth Soccer will host two entry level referee classes. The minimum age is 14 years old. The class will involve online courses as well as 13 hours of classroom/field training. The class fee is $20.00 (payable to TYSA) and if you pass the class as well as the online test the first year and 1/2 of registration is $45.00. The dates are listed below (you must attend all training's as well as the online work). The classroom is at 340 E Olive Ave Turlock Ca 95380 unless the numbers of students require us to move (if this becomes necessary you will be notified by email as a registered student).
Thursday June 30th-7:00pm to 8:00pm Instructions and orientation
Thursday July 7th – 6:00pm to 9:00pm Classroom
Friday July 8th - 6:00pm to 9:00pm Classroom
Sat July 9th – 8:00am to 12:00noon and 1:00pm to 4:00pm
Course #16574
Sunday July 24th -7:00pm to 8:00pm Instructions and orientation
Wednesday July 27th – 6:00pm to 9:00pm Classroom
Thursday July 28th – 6:00pm to 9:00pm Classroom
Friday July 29th - 6:00pm to 9:00pm Classroom
Sat July 30th – 8:00am to 12:00noon
To register for a class go to:
under register
click "Become a Referee"
on the left click "Register for an Entry Level Referee Course"
(Note you are in "East Region") scroll down and click "Online, Classroom and Field Session"
Or click on this link: https://cnra.gameofficials.net/public/class/classSearch.cfm?classTypeID=917
Select the course you want to register for (blue numbers on the left)
Verify this is the class dates you are interested in - near the bottom of the box you will find "To register for this course, Please Click Here"
Under "Don't have a USSF Registration account?" click on the box and create an account
Enter the required information.
Please go to the link below and read everything, print the Liability form and sign (bring to your first class):
If you have any question please email firstname.lastname@example.com
Please email email@example.com with any questions.


text:
Chook Standard Dog ToyMade from tough high quality fire hose these chooks are a great soft dog toy that dogs love the look of. 100% Safe and Non Toxic. Available with or without a bungy setup. Can be used with your existing "Home Alone" bungy. Durable soft toy that is made to last! Chooky rattles and will keep your furry friend amused for hours. Floats on water. Recommended for dogs up to 30kgs.
Code: 42889


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Home >> 3mmx6mm 4 Flutes HSSAL CNC Straight Shank End Mill Cutter Drill Bit 60mm Long
- Features: 3mm cutting diameter, 4 flutes, coarse teeth, 6mm straight shank, deep helical groove.
- Used widely in the milling machines or machine tools for milling the steps, recesses, vertical plane surfaces, etc.
|Overall Length
|60mm/ 2.4"
|Shank Diameter
|6mm/ 0.24"
|Cutting Diameter
|3mm/ 0.12"
|Cutting Depth
|12mm/ 0.47"
|Product Name
|End Mill Cutter
|Package Content
|1 x End Mill Cutter, 1 x Case
|Silver Tone
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Drivetime Monday 17 February 2014
Mary Wilson presents an information packed evening news magazine with all the stories of the day
Councillor Mary Hilda Cavanagh
Daniel McConnell, Group political correspondent with Independent newspapers.
Sunday Business Post Editor Cliff Taylor
One Big Switch is a campaign promising relief for energy consumers. Its Chief Executive is Oliver Tattan.
Custody, maintenance and barring orders - Della Kilroy continues her reporting from the Family Law courts in Dublin.
Exclusive reports from Drivetime's John Cooke who to some of the 160 Syrian Refugees adjusting to life in County Roscommon.
Graham Clifford reports on the plight of the population there.
Presenter: Mary Wilson


text:
Variety reports that Penelope Cruz attended the world premiere of The Inquiry — the Italian movie about an ancient Roman agent who investigates the resurrection of Jesus, which FoxFaith is releasing on Good Friday under the title The Final Inquiry — last Tuesday at the Los Angeles Italia Festival. Apparently one of the main characters in the film is played by Penelope's sister Mónica. But wait a minute, didn't this film have its world premiere at the Capri Hollywood Film Festival in Italy two months ago?
How many world premieres can a film have?
Related posts from FilmChat:
Peter T. Chattaway was the regular film critic for BC Christian News from 1992 to 2011. In addition to his award-winning film column for that paper, his news and opinion pieces have appeared in such publications as Books & Culture, Christianity Today, Bible Review and the Vancouver Sun. He has also contributed essays to the books Re-Viewing The Passion: Mel Gibson's Film and Its Critics (Palgrave Macmillan, 2004), Scandalizing Jesus?: Kazantzakis's The Last Temptation of Christ Fifty Years on (Continuum, 2005) and The Bible in Motion: A Handbook of the Bible and Its Reception in Film (De Gruyter, 2016).
- http://www.blogger.com/profile/03147734669353799982 Martin
This just goes to show that Penelope Cruz inhabits her own world.
- Anonymous
In Capri there were just some scenes/extracts from the movie, not the entire film at all. The real premiere it was in Hollyowood…We're waiting for the opening in US screens…


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Off-Island Gazette
Petition to stop Mount Rigaud development not realistic: mayorA petitioner's call to halt all development on Mount Rigaud is unrealistic, the mayor of the City of Rigaud says, because all land on the 250-metre-high forested mountain is privately ...
West Island Gazette
Pointe-Claire daycare operator calls for reinstatement of weekly garbage pickupA Pointe-Claire daycare operator has been pushed to desperate measures since the city ended weekly garbage pickup and the dirty diapers have piled up.
West Island Gazette
West Island moms petition Pointe-Claire to reinstate weekly garbage pickupA group of West Island mothers has launched an online petition in the hope of persuading the city of Pointe-Claire to reinstate weekly garbage pickup through the summer months.
Transgender rights: Planet Fitness incident overblown?THIS POST HAS BEEN AMENDED AT THE END If only she hadn't complained. If only Yvette Cormier had simply shrugged when she saw a transgender person in the locker room ...
Local News
Emma Czornobaj to appeal conviction in duck caseEmma Czornobaj will fight the June verdict that found her guilty of criminal negligence causing the deaths of André Roy and his 16-year-old daughter, Jessie.
Local News
Online petition seeks leniency for duck-saving driver Emma CzornobajMONTREAL – An online petition asking for leniency for Emma Czornobaj, who was found guilty of criminal negligence causing death in a highway crash, has collected more than 7,200 signatures. ...
Midhurst, Ontario: Change.org petition aims to stop urban sprawlI received the following in my personal email account today, from petition site Change.org. I don't really know a lot about this issue, but my Ontario readers are probably aware ...
LGBT issues: Why your bird might be constipatedHmm . . . I think birds in cages might be offended by a headline over an editorial on the Washington Times site, and might refuse to pee and pooh ...
Uganda's Sam Kutesa at the UN: A golden opportunity for activists?Speaking of arrogant leaders (see preceding post) . . . There is an understandable backlash against the appointment of one Sam Kutesa, Uganda's foreign minister, to become the ceremonial head ...
Lost chord recovered along with baby VictoriaWow! It is amazing how the baby Victoria story -- abducted from hospital, recovered within hours -- in Quebec has touched so many people around the world.


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Get an overview of this hotelArt Deco Chattanooga hotel in Hamilton Place with free breakfast
Popular property highlights
Located in Hamilton Place, this hotel is 1.3 mi (2.1 km) from Hamilton Place Mall and within 6 mi (10 km) of Tennessee Valley Railroad Museum and Concord Golf Club. Brown Acres Golf Course and Brainerd Golf Course are also within 6 mi (10 km).
Hotel Features
An outdoor pool, a 24-hour fitness center, and a 24-hour business center are available at this smoke-free hotel. Free continental breakfast, free WiFi in public areas, and free self parking are also provided. Additionally, coffee/tea in a common area, a seasonal outdoor pool, and meeting rooms are onsite.
Room Amenities
All 108 rooms feature comforts like pillowtop beds and premium bedding, while conveniences include refrigerators and coffee makers. For a bit of entertainment, LCD TVs come with cable channels, and guests will also find free WiFi and free local calls.Information missing or incorrect? Tell us!Opens in a new window
Fairfield Inn & Suites by Marriott Chattanooga East
Hotel Amenities
Hotel Amenities
Fairfield Inn & Suites by Marriott Chattanooga East features an outdoor pool and a 24-hour fitness center. Wireless Internet access is complimentary. Business-related amenities consist of a 24-hour business center and meeting rooms. Guests can enjoy a complimentary breakfast. This Art Deco hotel also offers coffee/tea in a common area, complimentary newspapers in the lobby, and laundry facilities. Complimentary self parking is available on site. A total renovation of this property was completed in 2012.
Fairfield Inn & Suites by Marriott Chattanooga East is a smoke-free property.
- Free breakfast
- Free newspapers in lobby
- Dry cleaning/laundry service
- 24-hour front desk
- Coffee/tea in common areas
- 24-hour fitness facilities
- Laundry facilities
- Meeting rooms 2
- Number of floors - 4
- Total number of rooms - 108
- Safe-deposit box at front desk
- Free self parking
- Outdoor pool
- Free use of nearby fitness center
- Elevator/lift
- Express check-in
- Express check-out
- Free WiFi
- Year Built 1991
- 24-hour business center
- Smoke-free property
- Number of buildings/towers - 1
- Outdoor seasonal pool
- Television in common areas
Family Friendly Amenities
- Family Hotel
- Outdoor pool
- Free Wi-Fi
- Laundry facilities
- Refrigerator
- Cribs/infant beds (complimentary)
Available in all rooms: Free WiFi
Available in some public areas: Free WiFi
Free self parking
Room Amenities
- Free cribs/infant beds
- Premium TV channels
- Premium bedding
- In-room climate control (air conditioning)
- Air conditioning
- Free local calls
- Refrigerator
- Coffee/tea maker
- Daily housekeeping
- Hair dryer
- Iron/ironing board
- Desk
- Cable TV service
- Hypo-allergenic bedding available
- Phone
- Free toiletries
- Connecting/adjoining rooms available
- Blackout drapes/curtains
- Free WiFi
- Pillowtop mattress
Where to Eat
Guests are offered a complimentary continental breakfast.
Nearby Things to Do
Recreational amenities at the hotel include an outdoor pool and a 24-hour fitness center.
The recreational activities listed below are available either on site or nearby; fees may apply.
- Golfing nearby
- Hiking/biking trails nearby
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
- Accessible bathroom
- Roll-in shower
- In-room accessibility
Hotel Policies
Check-in time ends at midnight
Check-in time starts at 3 PM
Minimum check-in age is 21
Check-out time is noon
Payment types
Children and extra beds
- Children are welcome.
- Kids stay free! Children 18 years old and younger stay free when using existing bedding.
- Free cribs (infant beds)!
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on property policy.
Government-issued photo identification and a credit card are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- Minimum Spring Break check-in age is 21 years old.
Minimum guest age is 21
No rollaway/extra beds available
Hotel Name
- Fairfield Inn Marriott Chattanooga East
- Fairfield Inn Marriott Hotel Chattanooga East
- Fairfield Inn Marriott Chattanooga East Hotel
We should mention
Children 18 years old and younger stay free when occupying the parent or guardian's room, using existing bedding. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.


text: Divxturka.net is using Extabit! Because Extabit is better than Hotfile, Netload and Rapidshare ! Click here and buy Extabit premium account! Plot: The psychiatrist and host of the radio talk show Talk Line, Dr. Sonny Blake, returns to Rosewood Lane, in Stillwater, one year after the death of her father to live in his house. Sonny was raised with brutality by her father and is a traumatized woman that was submitted to therapy by Dr. Cloey. Sonny's boyfriend, the DA Barrett Tanner, helps her to bring her things to her new home. On the arrival, her next door neighbor advises Sonny that the paperboy is a dangerous weirdo. Sonny finds that the paperboy has broken in her house and might have killed her father, but Detectives Briggs and Sabatino do not believe on Sonny and think that it is her imagination. When Barrett is attacked and is missing, Sonny and her friend Paula Crenshaw call the police but he is not found in the house. Is Sonny freaking out or is the paperboy an evil being? Genre: Horror | Thriller IMDB rating: 4.3/10 from 787 users Directed by: Victor Salva Starring: Rose McGowan, Lauren Vélez and Ray Wise Release Name: Rosewood.Lane.2011.720p.BluRay.x264-BRMP Size: 4.37 GiB Video: x264 | 1280×544 | 5863 Kbps Audio: English | AC-3 | 640 kbps Runtime: 1h 36mn Information: Code: http://www.imdb.com/title/tt1840388/ Download: Code: http://extabit.com/file/2cr1zwburboja/rosewood.lane.2011.720p.bluray.x264-brmp.mkv or http://extabit.com/file/2cr1zwbuskjhy/rosewood.lane.2011.720p.bluray.x264-brmp.part1.rar http://extabit.com/file/2cr1zwbuskmly/rosewood.lane.2011.720p.bluray.x264-brmp.part2.rar http://extabit.com/file/2cr1zwburyoie/rosewood.lane.2011.720p.bluray.x264-brmp.part3.rar Enjoy!


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Dan Denton, who sold Gulfshore Media to CurtCo Publishing in 2004, has bought back two of his old titles: Sarasota and Gulfshore Life. A CurtCo representative stated that the company is divesting the regional titles to concentrate on their growing title, Robb Report.
Denton formed Gulfshore Media LLC as part of the acquisition, but also has Florida Home Media LLC, which houses his Homebuyer magazines brand in addition to Orlando Home & Leisure. The Homebuyer brand includes Jacksonville, Naples/Fort Myers, Orlando, Tampa Bay, and Sarasota editions. Denton will continue to operate the business out of the Naples and Sarasota headquarters.
Regional Media Advisors represented Denton and Gulfshore Media in the deal.


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You missed it This great deal for Cloverleaf Tavern is over. But don't despair, we've got more great deals every day.
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Cloverleaf Tavern
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Start your lucky streak with a trip to Cloverleaf Tavern in Caldwell -- it was recently named the best beer bar in the Northeast and third-best in the nation:
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• Indulge in crab dip, made with real crab meat and a white wine-cheese sauce, and served with a baguette; then, sink your teeth into beer-battered fish 'n' chips, along with an icy glass of Cloverleaf's select drafts or cocktails
PAID VALUE EXPIRES ON May 29, 2022
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text:
The Whisper of Icy Waters
A fantasy of a world in its last bit of warmth.
I hear the whisper of icy waters as my last breath freezes before me.
I shall die in a few moments, the last of a breed, the last of a line, the last of a time that shall be no more.
I am Shaolin, a shadow that now fades into the Frozen Forever. To be gone forever, it seems far too long a time.
One more breath. Possibly another but few more than that.
Once this world was warm, drenched in the light that rained down from the Sister Suns. Waters flowed back then, down the mountains through the trickling streams, by the vine-covered cottages with their thick thatched roofs and their well-kept gardens, and then eventually, always eventually, into the Great Sapphire Sea.
In those years, the fields were filled with barley, like swaying seas of melted gold. In the fabric of their harvest, you could see the winds. These were not the winds of storms and frightful nights. No, these winds were but polite and playful breezes that brought the fragrance of the white Angel Flowers that dressed ever so delicately the green of the distant mossy hills. And when the wind turned, sometimes they brought the scent of the salty brine tossed into the air by the breakers that hit upon the rocky shore.
You always could hear laughter in those days, peaceful laughter that poured gently out of the old souls, joyful laughter that came with the sound of the children playing the sunshine fields. I will miss the laughter. Yes, I will miss it so. In particular, I will miss the warmth of the laughter and how it used to cozy my soul, like a fireplace cozies a winter's night.
But then again, the fireplaces have all grown stone cold and the campfires have gone out, one by one.
I am Shaolin, the last to remember the world the way it was before the coming of the Weather Wars.
Ah, yes, the world was, at one time, so warm and so wonderful. But no more.


text:
Many in the US are adding a conservatory to their home. A conservatory is a building or room that has a glass or tarpaulin roof and walls and is used as a sunroom or greenhouse. If a homeowner builds a conservatory to his or her home it is often attached to the house on only one side. Conservatories have become increasingly popular in the last decade because of the many benefits they offer. Find out about a conservatory tiled roof from a building expert.
Extra information about conservatory tiled roof
Why do many like having a conservatory?
Many like a conservatory because they are able to enjoy the beauty of the outdoors without worrying about rain or other weather conditions. Most conservatories are built with enclosed glass, giving those inside a conservatory a lovely view of nature. Conservatories are accessible from a home or outside. In addition, a conservatory is a wonderful way to be with the family inside while enjoying nature.
Conservatories add beauty and value to a home
What make conservatories appealing to many is that they can be altered or added to fit a home's outside style. Also, the size of a conservatory can be adjusted to match a family's needs. Most importantly, conservatories add value to a home. To be clear, a conservatory can add up to seven percent to a home's resell value. Some may not know it but a conservatory can also add additional space to a home. A conservatory could be used as a back to nature office space or used as a den.
Reasons to add or not to add a conservatory
Keep in mind a conservatory works well for those who have a garden that faces south, if it will not affect the size of their garden, if their kitchen and dining area lacks space or if a homeowner doesn't have a green house and wants to grow indoor plants. In addition, a conservatory would work well for those who can afford to spend at least 15,000-20,000. Also, a conservatory would work well for those who would like a space that could double as a children's play area for at least most of the year. Those who should not build a conservatory are those who already have a good kitchen and dining area space, if the area for their conservatory is not facing south or if they have a small garden.
What about maintaining a conservatory?
Also, it is important to note that conservatories need regular maintenance in order to prevent a buildup of algae growth on the roof panels and to prevent leaks. Most importantly, conservatories often become very hot in the summer and quite cold in the winter. In addition, a conservatory cannot be converted into a single story extension later on because the foundations are too weak to support an extension.
To conclude, many these days are adding a conservatory to their home and for good reasons. Find out more about conservatories from your local home improvement store or a building expert and see how they could add value and substance to your home!


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Experient Supplier of the Year Honorees Announced
Experient recognizes three supplier partners during its annual conference in Reno, Nevada as the best of the best in 2011.
Supplier of the Year awards recognize the best of the best of Experient partners each year and are an opportunity for Experient to honor those suppliers who demonstrate outstanding character and integrity, provide innovative ideas and solutions and maintain high quality customer service.
"These individuals are an incredibly strong and dedicated group of suppliers that add value to our organization by continually delivering exceptional results and superior performance,"
Experient honored Adam Michelin – national account executive, SmartSource Rentals; Michele Oberst – director, national accounts, Hyatt Hotels & Resorts; and Barry Tester – senior manager, conference management, The Venetian® Resort-Hotel-
Michelin was recognized for his ability to engage all areas of Experient to grow the SmartSource business. He stepped in and supported Experient with every aspect of its strategic events, and simply never says no when called on to assist. He is an outstanding Experient advocate, and continues to look for new ways for both organizations to partner and drive new business together.
Oberst was selected by Experient nominators for her drive and determination in thinking "outside the box" and for her ability to remain engaged with the account event after its close.
Tester has worked some of Experient's largest events held at The Venetian since 2006 and has been instrumental in supporting one of Experient's top clients. His customer service and forward thinking are outstanding, even when challenged with some of the most difficult events.
Experient leads the industry as one of the best-known and most respected brands in the event management world. Its core services include providing registration, housing, event planning and management, site sourcing/contract negotiation, and lead retrieval services for association, corporate and government clients. Experient employs professionals dedicated to fulfilling its vision of perfecting the event experience to deliver leading-edge thinking, experience and technology solutions for meetings, conventions and tradeshows around the world. Visit www.experient-
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ALDO Shoes - Malta – Cassedy €85
When you find a good pump, don't you want it in every hue? Photo by the lovely @johannaeolsson. #AldoMovesMe #AldoCrew
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Klinikum Offenburg, Offenburg, Germany
PURPOSE:CRP and NT-proBNP are predictors of cardiovascular mortality. The purpose of this study was to evaluate the relation between these 2 markers. Patients with an impaired lung function are at increased risk of cardiovascular disease. CRP levels have been associated both with cardiovascular mortality and the degree of pulmonary inflammation in COPD. Another aim was to investigate the impact of lung disease on the relation between CRP and NT-proBNP.
METHODS:CRP and NT-proBNP were measured in 697 outpatients (57.5±16.4 years) with dyspnea. The patients were stratified into 3 groups according to the CRP values [stratum I: CRP ≤; 5 mg/l (n = 510), stratum II: CRP >5–10 mg/l (n = 97), stratum III: CRP > 10 mg/l (n = 90)] and classified into 2 categories based on the presence (n = 176) and absence (n = 521) of heart disease.
RESULTS:In patients without heart disease, NT-proBNP significantly (p<0.001) increased from CRP-stratum I (adjusted mean: 48.1 pg/ml, 95%-CI: 44.1–52.4 pg/ml) to CRP-stratum II (65.6 pg/ml; 95%-CI: 58.5–73.6 pg/ml) and to CRP-stratum III (89.4 pg/ml; 95%-CI: 71.5–112.0 pg/ml) after adjusting for age, sex, body mass index, and arterial hypertension. Likewise, the CRP-strata were predictive (p<0.001) of NT-proBNP in patients with heart disease after adjusting for cardiac disorders with NT-proBNP increasing from 261.0 pg/ml (95%-CI: 204.3–333.4 pg/ml) in CRP-stratum I to 453.7 pg/ml (95%-CI: 369.4–557.2 pg/ml) in CRP-stratum II and to 788.5 pg/ml (95%-CI: 540-1150 pg/ml) in CRP-stratum III. The presence of lung disease and the severity of airway obstruction had no effect on the relation between CRP and NT-proBNP.
CONCLUSION:CRP is a predictor of NT-proBNP in patients with and without heart disease. This relation was found at NT-proBNP levels well below currently used threshold values to rule out heart disease.
CLINICAL IMPLICATIONS:An ongoing systemic inflammation puts an excess burden on the heart. This inflammation-related cardiac strain is not affected by the pulmonary status and might account for the increased risk of cardiovascular events in patients with elevated CRP.
DISCLOSURE:Siegfried Wieshammer, No Financial Disclosure Information; No Product/Research Disclosure Information
Tuesday, October 28, 2008
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i am currently training for a marathon in april. and i keep getting this very annoying pain in my right knee, which comes and goes. on a 20k run for example half way through it suddenly hurts so much i cant run any further, then i stop, wait for maybe 20 seconnds and keep on going a bit slower. and after a while the pain is gone.
then on a 30k run theres no problem at all. atm my knee even hurts when im just walking.
has anyone an idea whats wrong?
thank you for any help
I mentioned an issue with my knee and inner thigh to my physio (again, pain comes and goes and seems to be running down my inner thigh to my knee) and she recommended foam rollering of my VLM (the quad muscle on your inner leg, just above the knee).
She also made me sit on the treatment couch and flex my leg muscle. The knee cap went slightly sideways which is apparantly an indicator of tight quads. The foam roller (YouTube it!) and stretching seems to be helping.
Good luck
I had a bad knee few years ago which has come back to haunt me recently!
I wear a chowpat, i would recommend sports massage/physio and (like the others have said) lots of stretching and strengthening.


text:
Cleopatra Beach Bungalows
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Travel Blogs from Lovina Beach
The Day of the Dolphins and Lomi Lomi
... t stay still!
After breakfast we headed back to "our pool" again where again we were the only ones there. We stayed there until Lyn took his life in his hands and went for his Thai massage at 12pm. A thai massage is done with no oils and clothed. Basically, like the yoga yesterday the masseur stands and sits on you to pull you into positions to stretch you. I wish I had been there to see it, as I bet Lyn made some noises! The girl ...
The Day of the Long and Winding Road
... a province) there were lots and lots of people out waving the national flag, lots of convoys and within the last few miles of our trip an absolutely huge traffic jam that took us past an evening market and also a celebration fair. It was eye popping to see mopeds, traffic and pedestrians all try and flow through this one road. The police had given up and were sitting down drinking watching it all happen. Amazing.
Happy Birthday Sonia
... with a gas bottle. He went away again and came back with a step ladder and took the unit inside apart and he left again. It started spitting ice blocks across the room!! Anyway it all seems to be fixed now and our room is much cooler....certainly not the icebox Celeste has though!! We had dinner back at our "local". It was delicious again. The lovely ladies came out with Sonia's dessert on a platter with a candle and we all sang happy birthday.....a lovely ...
Beautiful South Pacific Ocean !!
... 0, 0, 0.701961); font-family: UICTFontTextStyleBody; font-size: 17px; line-height: normal; -webkit-composition-fill-color: rgba(130, 98, 83, 0.0980392);">
The rest of the day was spent in the pool, reading and basking under our parasols...taking all this in!
Bintang Downhill Cycling Tour. Kintamani.
... His other name, Ponie is like a small horse so he knows we will remember that!
Took a while to arrange all the right bikes for us all and make sure they are ok. Ponie wanted Callum and Lochlan to ride in the car for the first bit because it is steep, but we all reassured him that they would be fine so away we went. It was awesome!!! Just loved the down ...


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Wowsers! This is page is old, head to the LIVE Planet PDF Forum. It features more than 10 conferences, covering everything from beginner to in-depth developer and pre-press discussions. If you wish to continue... one & two archive covers 1999-2011 (160,000 pages).
New Forum | Previous | Next | (P-PDF) Acrobat 6.0
Topic: AVPrefsType - avpDisableAcrobatUpdate
Conf: (P-PDF) Acrobat 6.0, Msg: 132155
From: jehrlh300
Date: 5/4/2005 12:29 AM
I'm developing a batch program with VB 6.0 that will work for both Acrobat 5.0 and 6.0. The program will run without any user interactionj, therefore, I need to ensure that the Acrobat Update is not run while the batch program is running. I'm attempting to use SetPreferenceEX but I don't have the integer value for avpDisableAcrobatUpdate. There isn't a constant defined for avpDisableAcrobatUpdate in the IAC.bas or AVExpT.h that identifies the integer value. Is it possible to disable the Acrobat Update via OLE? If so, what is the integer value associated with avpDisableAcrobatUpdate?
The ultimate plug-in for Adobe Acrobat. Advanced splitting, merging, stamping, bookmarking, and link...Download free demo
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Planet PDF talks with another Master of the PDF Universe, Eugene Y. Xiong, Founder and Chairman of the Board at Foxit Software Inc. in Fremont California. Xiong is a quiet yet astounding achiever, you (usually) won't find him talking at conferences, exhibits, or publishings, but what you will find is the result of his leadership in places you would never expect.
The ultimate plug-in for Adobe Acrobat. Advanced splitting, merging, stamping, bookmarking, and link control. Take Acrobat to the next level.
OK, so you want to stamp your document. Maybe you need to give reviewers some advice about the document's status or sensitivity. This tip from author Ted Padova demonstrates how to add stamps with the Stamp Tool along with related comments.
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Holman Fenwick & Willan is launching in Dubai with the takeover of shipping boutique Hill Taylor Dickinson's Middle East office.
The transfer sees Hill Taylor Dickinson's three Dubai partners, Edward Newitt, Rula Dajani and Richard Jowett become partners of Holman Fenwick from February 2006.
The establishment of a base in Dubai will be a major boost to Holman Fenwick's core areas of shipping and insurance. Rival firm Clyde & Co is already present in the region.
Hill Taylor Dickinson's managing partner Malcolm Taylor said the move was due to a decision to refocus the firm's growth from its offices in London and Piraeus.
The office lease will also be taken over by Holman Fenwick, which secured its Dubai operating license in September. Hill Taylor Dickinson staff are being offered jobs at Holman Fenwick.
Meanwhile Holman Fenwick's Shanghai resident partner Andrew Cutler is leaving the firm for a P&I club in December, sparking a review of the firm's offering in the city.
Hong Kong corporate maritime partner Henry Fung is to move to Shanghai as office managing partner in Cutler's place. Additionally, former Hong Kong managing partner Peter Rees Smith is returning to practice after two years of retirement to become a consultant in Shanghai.