text: Sorry, this property is not available anymore. Photos Map 2 3 Property Place We bought here Features Bedrooms2Bathrooms3 Property Description CLOSE TO MONCARAPACHO AND OLHÃOMODERN TWO BEDROOM VILLA WITH BEAUTIFUL VIEWSOF THE COUNTRYSIDE AND THE ATLANTIC COAST ON A PLOT OF 4.120,00 SQ. M. LOCATIONThe property is located 5 minutes away by car to the village of Moncarapacho. The coastal town of Olhão and the nearest beaches are 15 minutes away. The International Airport and the city of Faro are both approximately 25 minutes driving. There are golf courses within 20 minutes driving and Spain can be reached in 40 minutes.TYPE OF PROPERTYThis modern villa was constructed in 1999. It is built on two levels and consists of 2 bedrooms, 2 bathrooms, kitchen, living/dining room, storage room, halls, WC and outside terraces. The master bedroom and bathroom are located on the top floor from where you have spectacular views.The overall size of the construction is 217,50 sq.m.The property is fully fitted and fully equipped. The contents of the house are available, subject to inventory and negotiation. It is connected to mains water. ACCOMMODATIONGround floor: Kitchen - 13.30 sq. m.Living/dining room - 33.22 sq. m.Halls - 8.70 sq. m.Bedroom 1 en-suite - 14.00 + 5.20 sq. m.WC - 1.40 sq. m.Storage room - 2.30 sq. m.Covered terraces - 58.60sq. m.First Floor: Bedroom 2 - 14.00 sq. m.Bathroom 2 - 7.00 sq. m.Hall - 3.36 sq. m.Covered terraces - 35.64 sq. m.GENERAL FEATURESAluminium security shutters on doors and windowsAluminium doors and windows with double glazingFly screensAir conditioning unitsWood burner in the living/dining roomCentral heatingFully fitted and equipped kitchenSatellite dish Automatic irrigation systemPrivate parkingEnergy performance rating CACCESSThe access to the property is via a country road only 500m away from the main road connecting Olhão and Moncarapacho. COMMENTSThis is a very comfortable property in the peaceful countryside with beautiful views of the surrounding hills and the Atlantic coast. The plot of land of 4.120,00 sq. m. supports some mature trees which include Carob, Olive, Pines, Almonds and other local variety. In the garden there are some ornamental plants, Cacti, shrubs, Oleander and flowers. The local shops, bars and restaurants are within 5 minutes driving distance from the villa. The property is ideal for a permanent or holiday home, and has a good rental potential. Request details This property listing (ref: MV348) is an advertisement supplied by Aimcliff Properties and does not constitute property particulars. While aplaceinthesun.com (APITS Ltd.) requests all advertisers supply correct details, it does not carry out checks on the information supplied and cannot be held responsible for any inaccuracies. Aplaceinthesun.com recommends seeking independent legal advice prior to any overseas property purchase.


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It's people like "you" that make it hard on the REST of US!<quoted text>Americans living in the land of the free did vote you American hater.
Shame to you and all your kind that have so much hate for a Republic that chooses its leaders by voting. You are a minority. You need to get with the program or leave our America. Or at least STFU you loser.
mealy mouthed pos!


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News By Tag
* Oncology Distress Management
* Psychosocial Distress
* Distress Assessment
* iPad interface
* Polaris Health Directions
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Polaris Releases Latest Version of iPad Interface for its Oncology Distress Management System
The enhanced iPad interface for Polaris's oncology distress management system will create a more user friendly experience for patients.
Modifications to the iPad platform include increasing the font size for questions, and adding larger option buttons. The number pad and keyboard now automatically pop up at the start of the assessment, simplifying the process for those who are unfamiliar with the iPad.
The addition of a stylus replicates filling in circles on a paper chart, which creates a more user friendly, familiar interaction for many patients.
The changes were based on feedback from current clients, and reflect Polaris's continuous commitment to deliver a platform that offers both maximum utility and user satisfaction.
The Polaris Oncology system is used by cancer treatment centers around the United States to facilitate routine distress screening, assessment, reporting and treatment referral for patients. By providing real-time information on a patient's psychosocial status, Polaris Oncology helps its clients deliver exemplary care and improve the quality of life for the cancer patients they treat.
For more information on the enhanced iPad interface or on Polaris Oncology, please send an email to: firstname.lastname@example.com or visit: http://www.polarishealth.com/
About Polaris Health Directions
Polaris Health Directions has been a pioneer in the development of behavioral health assessment and outcomes management platforms for nearly two decades. Polaris's enterprise cloud-based systems capture the information essential for determining the best course of care. Their advanced analytics help organizations execute quality improvement initiatives, apply needed services, identify cost reduction opportunities and, in many cases, indicate whether a particular course of treatment is likely to have a positive result. Systems are available for a wide range of health care settings; all support interdisciplinary coordination. By recognizing the nexus between psychosocial health and physical health, Polaris offers powerful solutions for better health care delivery. Follow Polaris on Facebook (http://www.facebook.com/
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3161 Paul Buchman Hwy
Plant City, FL 33563
Neighborhood: Plant City
Description Strawberry Town Cafe - Restaurant
Full hot breakfast, fresh ground coffee, fresh made deli sandwiches, soups, salads, burgers, fries, milkshakes, ice cream, strawberry shortcake.
Hungry Howie's Pizza & Subs208 N. Alexander St. , Plant City FL, 33566
Great counter-serve pizzeria chain best known for its always hot pizza and flavored crusts, such as sesame, garlic herb or butter cheese.
Connect Call DirectionPlant City
Features: American, Breakfast, Carryout, Catering, Delivery
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Doctor John Watson is looking for a new place to live when he is introduced to Sherlock Holmes, a peculiar man who happens to be looking for a roommate. Watson soon finds himself fascinated by Holmes' numerous eccentricitiesincluding the ability to deduce information about people without ever speaking to them. When a body is found next to the hastily scrawled word "RACHE," Holmes' scientific study of deduction is put to the test as Dr. Watson joins him in what will be the first of many thrilling investigations.
A Study in Scarlet is the first of Sir Arthur Conan Doyle's works to feature the now legendary detective Sherlock Holmes and his partner Dr. John Watson. Doyle's Sherlock Holmes stories have been adapted numerous times, including the 2009 and 2011 movies starring Jude Law and Robert Downey Jr., and for the popular television shows Elementary, starring Jonny Lee Miller and Lucy Liu, and the BBC's Sherlock, starring Benedict Cumberbatch and Martin Freeman.
HarperPerennial Classics brings great works of literature to life in digital format, upholding the highest standards in ebook production and celebrating reading in all its forms. Look for more titles in the HarperPerennial Classics collection to build your digital library.
To view this DRM protected ebook on your desktop or laptop you will need to have Adobe Digital Editions installed. It is a free software. We also strongly recommend that you sign up for an AdobeID at the Adobe website. For more details please see FAQ 1&2. To view this ebook on an iPhone, iPad or Android mobile device you will need the Adobe Digital Editions app, or BlueFire Reader or Txtr app. These are free, too. For more details see this article.
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ED Magedson – Founder
Ripoff Report
tradinghuaceInternet China
tradinghuace Sales of Electronics- Apple devices such as Ipad's, Ipod's etc. Internet
Does your business have a bad reputation?
Fix it the right way.
Corporate Advocacy Program™
Purchased $684 worth of electronics. Asked for wire transfer, which i did.Items were to be sent via DHL. Had DHL number. DHL showed shipment informatoin received, not picked up.Yesterday they told me they got caught by China Customs and wanted me to pay $200 for customs charges. They continue to make demands from me regarding additional payments.
The most damning part of the emails is their response from one of their agents: " Hope you can understand this. this is first time catch by China cutoms. all the product is original so catch it."
"Hope you understand this. Pay now" was sent many times. now i cannot get an answer from them.
I would like to report tradinghuace.com for fraudulently sending packages through China customs. It appears as this has been occurring for a long time and have gotten away with it.
This report was posted on Ripoff Report on 06/03/2013 04:49 AM and is a permanent record located here: http://www.ripoffreport.com/reports/tradinghuace/internet/tradinghuace-sales-of-electronics-apple-devices-such-as-ipads-ipods-etc-internet-1055861. The posting time indicated is Arizona local time. Arizona does not observe daylight savings so the post time may be Mountain or Pacific depending on the time of year.
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+34 93 2703410
Duc de la Victoria, 15 Barcelona 08002 Spain
Location This hotel can be found in the centre of Barcelona, near the University, the Plaza Cataluña, the cathedral and Las Ramblas. It is only 5 minutes from the nearest underground station and other public transport links. Various shopping facilities, restaurant, bars and pubs are also located in the hotel's vicinity. Facilities The hotel was built in 1950. Guests are welcomed at the accommodation, which has a total of 156 rooms. Most storeys can be reached by lift. Amenities include a cloakroom, a safe and a currency exchange service. Wireless internet access is available to travellers in the public areas. The hotel's culinary facilities include a restaurant, a café, a bar and a pub. Additional features at the establishment include a TV room and a playroom. Guests arriving by car can leave their vehicles in the garage or in the car park. Available services and facilities include medical assistance, room service and a laundry service. Active guests can make use of the bicycle hire service (for a fee) to explore the surrounding area. Rooms Each of the rooms is appointed with air conditioning, central heating and a bathroom. The standard features of most rooms include a balcony. A king-size bed ensures a good night's sleep. A safe and a minibar are also available. Additional features include a fridge and a mini fridge. Internet access, a telephone, a TV, a radio and a stereo system add to the comfort of the holiday. Amenities in the bathrooms include a shower. A hairdryer can also be found in each of the bathrooms. The hotel offers family rooms, non-smoking rooms and smoking rooms. Sports/Entertainment For a fee, travellers can take advantage of biking/mountain biking. Meals It is possible to order breakfast. Payment The following credit cards are accepted at the accommodation: American Express, VISA, Diners Club and MasterCard.


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What small appliance would you like to have
Posted by + Show Post
that u don't have?
Replies (31-40):
Blender, toaster, coffee maker. All I have is a mixer and crockpot. Lol
A Vitamix and a yonanas .....very badly
A juicer. I had one, but it died almost a year ago and I never got around to replacing it.
by Kira on Sep. 21, 2012 at 10:18 AM
New blender mine is lost lol
I want a blender, maybe a rice cooker and a 7 qt. crock pot...I have a 6 1/2 qt.
Add your quick reply below:
You must be a member to reply to this post.


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Finally!!! I've blogged about these tools so many times now and have done screencasts about them too. Finally you too can play with them and download them. Heres what the email I got says:
"…Business Desktop Deployment (BDD) 2007 has undergone many changes to significantly ease the deployment of Windows Vista, including new out-of-the-box imaging technologies, XML-based migration scripts, new tools for image engineering (ImageX and System Image Manager), and new unattend XML format. Another huge breakthrough with Windows Vista is Hardware Abstraction Layer (HAL) independence and language neutrality; this means that organizations can get to a minimal number of standard images across multiple hardware types….
…BDD 2007 includes guidance based on every stakeholder role involved with desktop deployment, from business decision makers to end users…
BDD 2007 also introduces the new Deployment Workbench, which enables users to build and manage multiple OS configurations, define network deployment points and network shares, inject drivers, attach language packs, and chain applications. It even helps generate ISO and WIM images using Windows PE that can be deployed in a networked environment or using DVDs offline. BDD 2007 also alleviates much of the scripting requirements of previous deployment practices by incorporating a stand-alone task sequencer derived from System Center Configuration Manager 2007. BDD continues to offer the flexibility for Zero Touch Installation with Systems Management Server 2003 and Lite Touch Installation with minimal infrastructure requirements…"


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Originally posted on Fox - The Hockey Guy | Last updated 1/4/13
St. Louis Blues prospect Ty Rattie scored Canada's lone goal against the United States in the semi-finals of the World Junior Championship in Ufa, Russia.Goaltender Jordan Binnington, another Blues prospect, played the second half of game after Canada fell behind 4-0. Both he and Rattie should benefit from their participation.But hockey fans in the Great White North were pretty sour after the U.S. stunned Canada 5-1 to advance to the gold medal game. The Canadians will play for the bronze medal, which was definitely NOT their goal coming in.Losing, Rattie told reporters after the game, is "the worst feeling in the world."What went wrong?"They came out quick," Rattie told reporters. "We didn't. We didn't respond until the third – and that was too late."Team USA coach Phil Housley, a former Blues defenseman, earned a big victory in his second career. One of his key performers was Harvard forward Jim Vesey, son of a former Blues and Boston Bruins forward by the same name."We got the start w
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Marketing Automation Platform
Designed for use with JGA spray guns, this strainer mounts on the fluid inlet and allows the filter screen to be cleaned or replaced without removing the stainer housing. It also functions as a trigger guard.
Accessory #: VS
Material: Plated Brass
Parts: Screen VS-58-K10
First Thread: 3/8" NPS (M)
Second Thread: 3/8" NPS (F) Swivel
Max. Working Pressure: 300 PSI PSI
Mesh Size: 100
Micron Size: 149


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Happy Friday everyone! Here is a Spooktacular offer just for you! This weekend only and while supplies last!! Enjoy~ Have a great weekend! And Happy Creating~ Nanci … [Read more...]
'Tis Halloween with Cards, Stickers & More
"When witches go riding & black cats are seen the moon laughs and whispers: 'Tis Halloween", this is just one of the spooky Halloween cards we are featuring in our Halloween card kit. It's a favorite of mine for sure! You can view our entire card kit on our website. Today I would like to … [Read more...]
Get Ready For a Spooky Halloween
Halloween is just around the corner, have you started decorating yet? If not that's okay because you still have time, PLUS we have the cutest Halloween banner to get you started. I've been busy putting up my fall and Halloween decorations and it's been so much fun!! This year I created a … [Read more...]
World Card Making Day
Today is World Card Making Day!! We want to celebrate with you by offering you 25% off all previously released card kits. This includes our clearance kits and stickers. Visit our shop to stock up today!! Use coupon code: WCMD25off during checkout to receive your discount. Discount does not … [Read more...]
Preserving Autumn Memories
It's that time of year again, fall has arrived and so has our October card & layout kit release! This month with are featuring the beautiful Falling Leaves collection by Photo Play Paper. This is our first time featuring this fabulous company and we have definitely fallen in love. The rich … [Read more...]
Spooky Halloween Banner
Summer has officially ended and fall has arrived! It's my favorite time of year…cool nights, pumpkin lattes, corn mazes, beautiful fallen leaves, haunted houses and decorating. I've already got my fall and Halloween decorations out and well folks it's time to decorate!! I have to admit one of my … [Read more...]


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Once again, the best place for a base camp to boat or kayak into Discovery and Desolation water ways, this while you relax and enjoy the scenery knowing your boat is secure in an excellent marina with essential amenities only a short walk "up-the-hill". Staff at Taku are to be commended for ensuring guest the best possible stay and making a return trip mandatory. Keep up the superb work and have an excellent fall/winter, see you soon. Walt & Pam / Intimate Cabin / Oct 11 to 14 (Courtenay, BC)
- Official Description (provided by the hotel):
- A magnificent seaside resort with a perfect blend of laidback ambience and luxurious comfort. Enjoy views from all suites and cabins. Our accommodations will meet your needs and budget and all have a full kitchen and balcony. Alternately, there are forested campsites or the excellent marina for you to stay. On-site, you can enjoy cookery courses, the hot tub, tennis, kayaking, basketball and bocce and more. Quadra Island also offers activities such as golf, hiking, art studios and much more. Our professional and attentive staff look forward to hosting you. The complete Discovery Island vacation experience awaits you at Taku Resort. ... more less


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Rihanna has sold over 25 million albums worldwide and dominated music charts in the U.S. with singles such as 'Umbrella" and 'What's my name". The single 'S&M", however, has fizzled on the charts, and the video has been banned in some countries for its sexual content.
In the suit, the photographer said the singer had appropriated eight of his images into the video, such as a shot where she is shown in profile against a blue background with a piece of candy on her tongue. LaChapelle said her video copied the "composition, total concept, feel, tone, mood, theme, colours, props, settings, decors, wardrobe and lighting" of his work. He is suing for unspecified damages.
A source at LaChapelle"s studio told celebrity website Radar Online that initially fans thought the photographer had directed the video. "Interns told us that fans were buzzing about the video and wanting to know if David had directed it. Then the phone in the office started ringing off the hook, everyone was like 'wow it"s amazing – it"s the exact same," the source said.


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Milwaukee hip hop artists "The Firgureheads" collaborated with Good Friend Inc. for the video.
Rappers posts an apology on his blog for his words, vows to educate himself about autism.
Get the latest on research, programs, services, Walks and special events in your area.
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Telephone booking delivery time, make sure to reach the destination!
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Online 5+ minutes, browse 10+ products,Get $5 coupon!
TE7133YES Europe fashion cross v neck off shoulder empire waist tight hip halter dress
Product Detail:
COLOR: Black, Red, White
Fabric: Ramie
WEIGHT: 0.280kg
SIZE: One size
LENGTH: 82cm, Bust: 82cm, Waist: 66cm, Hipline: 85cm


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Beverly-Hanks & Associates REALTORS®North Asheville
Email: [email protected]
Cell: (828) 776-9999 Office: (828) 251-1800
Team Member Since 2016
If I don't have children, why should I care about a community's schools?
Even if you don't have school-age children, schools matter to almost everyone. A 2013 realtor.com® survey of nearly 1,000 prospective homebuyers showed that 91% said school boundaries were important in their search. The same study found that half of homebuyers are willing to pay more than their budget, and more than half would give up a bedroom or garage to get into the right school. Homes in better districts tend to enjoy more price stability and sell more quickly than homes in less desirable school districts. At beverly-hanks.com, each home listed for sale is linked to each school's report card as reported by the independent website education.com.


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Toronto's Must-Visit Summer Festivals For 2016
Allison Eberle | Posted 05.17.2017 | Canada Travel
Read More: Toronto, Toronto Jazz Fest, Toronto Ribfest, Caribana, Festival-of-India, Blog, Canada Travel News
Toronto is the place to be this summer. Whether you're into photography, music, family-friendly fun, dining, flowers or theater, there's a summer festival in Hogtown that's guaranteed to interest and excite you. In fact, there are so many festivals on schedule between May and September, that you may never want to leave. The following are six of the best summer festivals happening this year in Toronto.


text: McNabb hungry to prove T.O. wrong Beneath Eagles QB's joking demeanor, he's burning to have great season By Don Pierson MSNBC contributor It's impossible to pinpoint the exact time when Terrell Owens felt irreversibly disrespected by Donovan McNabb. It's especially hard to believe Owens' contention that it might have had something to do with him being open and not getting the ball, which he mentioned in his recent book. Not that Owens wasn't open, of course, but this is the same book in which Owens contends he was misquoted. But the time that makes the most sense in a rather senseless saga was after Owens got hurt during the 2004 season. Asked incessantly about the effect of losing his star receiver, McNabb pointed out that the Philadelphia Eagles had won games before Owens arrived and would win without him. Whether McNabb was being sincere, naïve, insensitive or all of the above, his comments were enough to make Owens take notice. What? He's saying I don't matter? To Owens, it was a hurtful remark. A more diplomatic and sensitive McNabb might have altered his answer to placate his mercurial teammate. He might have said something about how much the Eagles would miss their great superstar and how they wished him godspeed in his recovery and how they would do their best to struggle along in his absence. Instead, McNabb chose to buoy the spirits of the other receivers who would be taking Owens' place. The relationship was never the same. Now McNabb has reason to feel disrespected. Owens continues to pour salt in old wounds to the extent that McNabb's father has compared the receiver's behavior to "black on black crime." That's serious stuff, enough to convince you that underneath McNabb's humorous attempts to brush off Owens' charges, there is a ticking time bomb. It is set to go off on Oct. 8, when Owens and his new Dallas Cowboys visit McNabb and the Eagles in Philadelphia. Already, Owens has been reported to count his workout reps with the numbers 10 and 8 to constantly remind himself of Oct. 8. McNabb doesn't even have to circle his calendar. Recovered from surgery to correct the sports hernia that destroyed his 2005 season, McNabb is eager to make good on his comment that the Eagles won before Owens arrived. He has no choice in the matter. According to Owens' book, McNabb was jealous. Owens said when he told McNabb he was open in a game against the Giants, McNabb told him to shut up in the huddle. Wrote Owens: "I was concerned that Donovan resented the fact that I was getting so much of the Philadelphia glory that used to be his. I wanted to believe that I was wrong. I wanted to believe that Donovan didn't throw me the ball as coach Reid had called for because he made an honest mistake. ... I wasn't trying to steal Donovan's thunder; I was trying to make us a legendary tandem like Joe Montana and Jerry Rice. That was what I wanted for us, but in that instant in the huddle I knew he wasn't like Joe or Steve (Young). They were positive, respectful and encouraging in the huddle toward their receivers. ... The only thing I could think of was that he disliked all the credit I was getting on his team." McNabb's version: "He told me, 'Hey, I was open on that. Throw me the ball.' And you guys believe that, I'm sure. I mean, you think about that." Owens implies that McNabb lost the Eagles' locker room. But McNabb says, "I've never felt I lost the locker room and I don't feel I need to get the locker room back. To be honest with you, the way that you win anything is by winning games. The way of handling it for me is just to get out on this football field, make plays and then win games." Owens claimed one of the Eagles' offensive coaches told him McNabb gets tense in big games. "It's funny how they would just come to him," McNabb said. "Why wouldn't they just say something to me? To say that I can't play in big games, I don't think that's a true statement at all, so I don't get offended by anything he may have said in his book that he was misquoted." As for Owens' implication that McNabb influenced management's decision to suspend Owens, McNabb replied: "If I had that much pull, a lot of changes would be made." Presumably, one of the changes would have been to add more firepower after Owens departed. As much as McNabb might dislike Owens personally, he's smart enough to admit: "He's a great player. He works hard. He gets out on the field and makes plays. That's all you ask." The Eagles added Jabar Gaffney, who caught 55 passes last season as the No. 2 receiver behind Andre Johnson in Houston. Obviously, coach Andy Reid's hopes lie in the return to full health by running back Bryan Westbrook and McNabb. To win without Owens, McNabb will have to remember that he did it with his legs as well as his arm. McNabb hates the thought of being labeled a mobile quarterback, but the truth is he was always more effective as a two-dimensional player. There are scouts who have turned skeptical about McNabb's desire or ability to run as well as he once did. If he can't or won't, they fear he is no more than an average quarterback. McNabb tried to play through injuries last season, but threw costly interceptions in the fourth quarter in each of his final three games. The last one was against the Cowboys. Safety Roy Williams returned it 46 yards for a touchdown with 2:43 left to lead the Cowboys to a 21-20 comeback victory that dropped the Eagles' record to 4-5. That's the same Roy Williams' whose 2004 "horse collar" tackle of Owens, now an illegal maneuver, injured the receiver and was the beginning of the end. Owens and Williams are now teammates, and it's McNabb against the world. "The good thing in life is that you can put the past behind you and move on and kind of create your own future," McNabb said. "This team is definitely hungry. This team is looking forward to getting out there and answering the critics." Nobody is hungrier than McNabb, not even Owens. http://msnbc.msn.com/id/14151371/


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A confident Martin Mears stepped back into a high-profile role last week at the end of what must surely be the most acrimonious and controversial Law Society elections ever.
Mears took to the Chancery Lane stage alongside the outgoing president, Tony Girling, to launch a client care booklet for solicitors, produced by the Office for the Supervision of Solicitors and edited by Mears.
Phillip Sycamore, his rival candidate for the presidency, was also at the launch.
The results of the election were expected on Monday afternoon as The Lawyer went to press. The winner will become president on Thursday at the Law Society annual general meeting.
Only five months ago it seemed that Mears' hopes were in tatters after his former ally Robert Sayer disowned him, claiming that he was only interested in power.
But his campaign was ignited by the announcement of a £450m shortfall in the Solicitors Indemnity Fund and the leaking of minutes of a Sycamore campaign meeting which showed it apparently plotting a dirty tricks campaign against him.
A predicted low turn-out was expected to favour Mears, although the result may be close. There is also the possibility that tactical voting may see Mears elected as president with Sayer as deputy vice-president.


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The average price of a home in England and Wales has passed £300,000 for the first time – and it could take someone in London almost 46 years to save for a deposit.
Figures compiled by property website Rightmove showed the typical price of a property coming on the market increased from £299,287 in February to £303,190 this month.
For London, a new record was set, with the average price of a home hitting £644,045.
Meanwhile, a report by estate agents Hamptons International found Londoners' best chance of buying a home was if they did so with someone else.
Its figures showed couples face an eight-year wait to save enough for a 15 per cent deposit, compared with single people who face a wait of around 45 years and nine months.
Rightmove said the new record across England and Wales is being driven by momentum spreading across the north and west of the country, rather than in London, which has previously been the engine of house price growth.
It said the London housing market is now split, with some boroughs seeing prices surge upwards and others seeing them drift downwards.
Rightmove director Miles Shipside said: "While the start of 2016 has seen an encouraging but modest uptick in the number of properties coming to market, demand and momentum have combined to push prices over £300,000.
"On average, 30,000 properties have come to market each week over the past month, up by 3 per cent on this time last year, but there are insufficient numbers of newly listed properties in many parts of the country to meet demand."
Some reports have said that a three percentage point stamp duty hike for buy-to-let investors, which starts on April 1, has prompted a rush of people snapping up homes in recent months to beat the deadline.
Nicky Chute, from Foxtons in London, said: "Last year the volume of sales fell across all London zones but least so in zones three to six, whilst prices continued to rise.
"For example, last year 514 properties were sold in Pimlico and Westminster with an average price of £1.2 million, making the market worth £618 million.
"In Walthamstow, where Foxtons opened a branch in 2015, 1,722 properties sold for an average of £395,000, amounting to £680 million in sales. This now makes Walthamstow in outer London a larger market than Pimlico and Westminster in central London."
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text:
"And I can't breaaath, without you! But I have to!" I sang, dancing around the empty dorm. I carried on singing all the songs I knew. Until a very suprised looking Thunder came in. I blushed beet red!
"Sorry, um, is Olli here?"He asked.
"No. She's out in town, so is everyone else. I didn't go."I said breathlessly.
"Oh, even Shadow?" He asked.
"Yeah. He tried to make me come, but I sat on the floor until he gave up!"I grinned. He edged into the middle of the room.
"Um. Will you tell her I came?"He whispered. Looking me in the eyes. Making me shiver.
"Y'know, you make me shiver when you do that!"I exclaimed. He started to look angry. But I carried on, I didn't mean to, I just did!
"And, you look weired when you get angry! Your nostrels go all big in a VERY unattractive way! I mean. In books, the boys are meant to look all georgous, but you? Yeah, you just look stupid!" Why couldn't I shut up??? Why?? It was like some one was MAKING me! SHUT UP SAVANNA! SHUT UP! A odd, muffled noise came out of my mouth, I was trying not to speak.
I grabbed some papaer and scrawle d on it, for him to read: It's not me!
I'm being controlled!
"Are you making fun of me?! HOW DARE YOU!"He screamed at me. My mouth opened and spoke for me.
"Oh, give over! Whocares about you? I mean, Olli doesn't! Awww, baba gonna cry? cry baby gonna cry and run to mummy? Awww, how cute! I'm not suprised Olli dumped you for Spark! I mean--"My snide comments were cut off by my scream of pain. I felt like a white hot iorn bar had been shoved into my chest. I fell to the ground, screaming. I was sprawled on the mat, wriggling, hoping it would go away.
It didn't.
It didn't ever! I lay on the floor, writhing in pain. I shrieked at him.
"PLEASE! I WAS BEING CONTROLLED! IT WASN'T ME!"I shrieked.
I saw him, through my tears, walk out the room. Leaving me on the floor. I felt like I wanted to die.
I heared voises. I screamed for help. Although my voice was hoarse from my previous 'screaming for help' sessions.
Filla came bursting in. Followed by everyone else.
"OH MY GOD!"Yelled Olli, "WHAT HAPPENED?" Shadow came rushing over, his handes were nice and cool on my clammy forehead.
"Th...Th...thu." I screamed silently. No words could escape my mouth.
Spark picked up my note.
"Some one made you prevoke Thunder?" He said, horrified. Shadow groaned.
"If theres something you know, Shadow, you need to tell us!"Cried Lillie and Millie.
"Mel, popular girl, asked me out, and I turned her down. She said she'd get revenge. And now she has."He whimpered. He's NEVER whimpered before.
"LILLIE!GET COCO!"Barked Millie. Lillie ran out.
About 5 minites later, Coco came rushing in.
"What happened?"She asked. I don't know what the fuss is! I don't think he even did anything to me on the outside!
I tried to sit up, Olli pushed me down. I stayed.
"T...Thunder, he...he...attked m..m...me. And whats wrong with my face?"I said and asked.
"Um. Look in the mirror, Sav." Said Toni carefully, she was prepping for a emotion twist.
"Okay, but I really don't thing....OH MY GOD!"I yelled.
My face!!!!MY FACE!!!!It...it....it was. Well. Beautiful. I know Toni was making me happy. But, it really was lovely. I was two golden ring things around my face, well, like, y'know how goths do their makeup? It was a golden version of that! And my freckles were now golden!
"It's...wow."I stammered. They beamed. They knew it was nice too! "If it's pretty, why does Coco have to remove it?" And besides, it was a phycic battle scar! I wanted it!
"Well. If you keep it, Thunder will get in troubl!"Olli blurted.
"Oh, and you'd choose Thunder over me?"I sad indegantly. She looked lost for words. I could feel the tears running down my cheeks.
And suddnely, it wasn't about the scars anymore. It was about friendship. She'd been so caught up with Spark. She had remembered everyone else except me. I was the odd one out. I got up. I felt better. And ran out the room. I heard them calling my name, but I carried on. I didn't fit here. I'd ruined it for everyone!
I don't know whether I was feeling other people sadness, or just my own army of sad thoughts. But I ran out into the garden. Into the hole in the hedge. And into the little patch of ground that I had claimed mine. I sat donw, sobbing. I was being a drama queen, I know, but I needed to be alone...


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A World at It's End
Book by: Fern Snecker
Status: Finished
Genre: Action and Adventure
Chapter12 (v.1) - She's back
In the morning, I could feel the light tapping of a feminine finger. I woke and turned to the figure.
There, I saw her. Her hair curly blonde hair tucked neatly behind her ears, bringing out the strange lavender in her eyes. She smiled wide with her thin lips. And through her gorgeous face was a long curly strand of burgundy.
"Q?" I asked, breathing heavily. 'Q' was my nickname for Quincy. She laughed and hugged me.
"I missed you, Halle," Quincy whispered into my ear. I sat up and Quincy sat next to me.
"How'd you get here?" I asked her.
"Remember, you broke me free."
I remembered. I thought I had just taken her away at the time, not freed her.
Our conversation was interrupted when Jean came in with a brown leather book, and opened it. I recognized my short and stubby handwriting. He tossed it to me. Only three short entries.
Jean sat next to me rested his head on my shoulder. Quincy giggled.
Dear Diary, DECEMBER 2ND (probably)
The paper feels amazing, I missed this. Lots to write about, I'm only going to say one thing though. Through this whole experience, I've cracked, loved , and even murdered, but I still kept strength.
Strength. I like that word, it feels rough on the mind, but easy and beautiful on the eyes. Like Jean.
All I know is, this world needs too be saved.
With all due respect,
Halle Francesca Burner
I closed my book. Jean lifted his head, "Hungry, girls?" I nodded along with Quincy. Before leaving, Jean planted a kiss on my cheek.
"Does he like you?" Quincy asked me. I sat back.
"Probably," I told her. Lie, I was certain he liked me.
"Probably? Have you seen the way he looks at you?" Quincy sassed me.
"No, I actually haven't." I actually haven't. Maybe I should see how he looks at me. For the rest of our time alone, Quincy and I talked of the old days, where we could go outside and play.
Jean came back and held up three sandwiches, three bottles of water and six pieces of beef jerky. He split the food equally and sat down to eat himself.
He watched me as I ate. I suddenly caught him off guard and stared back at him. The look in his eyes was beautiful. His interesting eyes glittered and shimmered with his dilated pupils. He blushed when I stared back.
"I love beef jerky," I told him. He smiled to himself in satisfactory.
© Copyright 2017 Fern Snecker. All rights reserved.
Add Your Comments:
Phew! I'm glad everything's back to normal! I was so happy when Halle saw Quincy again! :D Short but good chapter! KMU :)
Other Content by Fern Snecker
Book / Action and Adventure
Book / Action and Adventure
Book / Romance
Short Story / Mystery and Crime
Book / Thrillers
Short Story / Young Adult


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Help others choose the best products...Write a review
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Bobby inherent to toddlers and children of preschool age. Ever since the first steps provide children with support and confidence, and they are a source of fun and joy of movement. Bounce Classic 5 Maxi is designed for older children from about 3 years, and last, because of the load 50 kg a really long time. It is equipped with three massive wheels, ensuring stability.
35 kg
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35 cm
Specifications can be changed without notice. Images are for illustrative purposes only. Retail Price (MSRP) means the manufacturer's/supplier's suggested retail price.
Link to Manufacturer's Website: Enter link to the external review


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(December13th.13) Today, Europe's flagship Mixed Martial Arts promotion, BAMMA, held its weigh ins for the event "BAMMA 14: Daley vs. da Silva", to be held at Birmingham's LG Arena tomorrow night. The weigh ins which took place at 2pm at Birmingham's Hilton Metropole hotel, were overseen by referee Marc Goddard.
BAMMA is proud to announce that all fighters made weight the first time they hit the scales. See below for the official weigh in results:
Daley 169.6
Da Silva 170.8
Betorangal 168.8
Wallhead 169.2
Lewis 169.4
Edwards 171
Howard 186
McLeman 185.8
Shah 145.2
Craven 145
Wilde 155
George 156
Menzies 169.6
Samuda 170.6
Widmer 185.6
Hallam 185.6
Saville 145
Duquesnoy 145.4
Rees 134
Arthur 135
"BAMMA 14: Fight Night Live" broadcasts LIVE from the LG Arena in Birmingham (UK) tomorrow night, Saturday 14th December. The televised main card features Paul 'Semtex' Daley's return to BAMMA as he faces Blackzilian Romario Da Silva in the headlining bout.
See below for the TV Channels around the world where you can tune into the BAMMA 14 LIVE main card plus extended highlights this Saturday night:
- (UK) Channel 5 Star (Sky – 176, Virgin Media – 151, Talk Talk TV – 3, Freesat – 131) LIVE from 9PM -11PM Main card & extended highlights
- (US) AXS TV – LIVE From 4p ET/ 1p PT
- (Canada) Fight Network – LIVE from 4p ET
Please check Local Listings for times:
- Abu Dhabi TV
- Transylvanian Media Group Romania
- Sony Russia
- (Pan Europe) Extreme Sports
- Setanta Africa


text:
Dr. Hillary Charles MD Patient Reviews
- Obstetrics and Gynecology Glendale, AZ
Overall Rating
3 Patient Reviews
- Wait Time 32 minutes
- Easy Appointments
- Promptness
- Friendly Staff
- Fair and Accurate Diagnosis
- Bedside Manner
- Spends Time With Patients
- Appropriate Followup
Showing 1 - 3 reviews
5.0 of 5
June 24th, 2013
I liked Dr. Charles. She listened to my concerns and worked with me while addressing them. She was patient and took the time to explain things. I thoroughly enjoyed her sense of humor and thought that her beside manner was very kind. She diagnosed my issue and gave me wonderful information when I needed to seek out a specialist. I was very pleased with her.
1.0 of 5
May 1st, 2012
The Dr was not keen in listening to my problems so ofcourse she wouldn't suggest me any treatments. I visited her twice but it was pure waste of my time and money. I personaly wont suggest her to anyone.
2.0 of 5
April 27th, 2011
The office staff is horrifically rude. If you call for an appointment expect to be put on hold immediately for about 5 minutes. And when the staff person gets on the line you will be rushed through your call. I have called the after-hours line and never received a call back. Dr. Charles uses sarcastic humor at inappropriate times and is oftentimes guessing on diagnosis. The bedside manner is very cold and hurried. I do not recommend this office to anyone.
Health Guides
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Create an account or sign in to your Tiffany.com account to permanently save this item to your Saved Items.
Shipping Enjoy complimentary shipping and returns on your order. Learn more about our Shipping Options & Rates
The Tiffany Blue Box® All purchases arrive in the renowned Tiffany Blue Box®, tied with a white satin ribbon.
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A symbol of life's beginning, Elsa Peretti's Bean design is defined by smooth contours and sensuous curves. This familiar organic shape finds elegant expression in jewelry and accessories of gold, silver, carved stone and lacquer.
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text:
Education for Self-transformation
€ 121,49
pdf eBook
Sofort lieferbar (Download)
Oktober 2011
BeschreibungExemplifying what it advocates, this book is an innovative attempt to retrieve the essay form from its degenerate condition in academic writing. Its purpose is to create pedagogical space in which the inner struggle of 'lived experience' can articulate itself in the first person. Working through essays, the modern, 'post-secular' self can guide, understand, and express its own transformation. This is not merely a book about writing methods: it has a sharp existential edge.
Beginning by defining key terms such as 'self-transformation', Kwak sketches the contemporary debates between Jürgen Habermas and Charles Taylor on the status of religious language in the public domain, and its relationship to secular language. This allows her to contextualize her book's central questions: how can philosophical practice reduce the experiential rift between knowledge and wisdom? How can the essay form be developed so that it facilitates, as praxis, pedagogical self-transformation? Kwak develops her answers by working through ideas of George Lukács and Stanley Cavell, of Hans Blumenberg and Søren Kierkegaard, whose work is much less familiar in this context than it deserves to be.
Kwak's work provides templates for new forms of educational writing, new approaches to teaching educators, and new ways of writing methodology for educational researchers. Yet the importance of her ideas extends far beyond teaching academies to classroom teachers, curriculum developers - and to anyone engaged in the quest to lead a reflective life of one's own.
InhaltsverzeichnisPreface; Paul Standish.
- 1. Introduction: Education as Self-transformation and the Essayist Form of Writing: Education for a Post-secular Age.- PART I - George Lukács: Practice of Philosophy for Existential Fulfillment.
- 2. A Reflection on the Relation between Philosophy and Life; through Hans Blumenberg's Work.
- 3. A Response to Modernity Between Reason and Faith: Kierkegaard's Ideas of Ethical Self and Subjectivity.
- 4. Practicing Philosophy, the Practice of Education: Exploring the Essayist Form through Lukács' Soul and Form.- PART II - Stanley Cavell: Practice of Education in the Essay-Form.
- 5. Stanley Cavell's Ordinary Language Philosophy as an Example of Practicing Philosophy in the Essay-form: In Search of a Humanistic Approach to Teacher Education.
- 6. Philosophy as the Essayist Form of Writing: Cavell's Concepts of Voice, Method, and Text.
- 7. Cavell's Essayist as the Political Self: Implication for Citizenship Education.
- 8. Conclusion: The Essayist Form of Writing for a Tragic Form of Subjectivity.- Index.
Untertitel: Essay Form as an Educational Practice. 2012. Auflage. Bibliographie. eBook. Sprache: Englisch. Dateigröße in MByte: 1.
Verlag: Springer Netherlands
Erscheinungsdatum: Oktober 2011
Seitenanzahl: x150
Format: pdf eBook
Kopierschutz: Adobe DRM


text:
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Surrounded by plush sheets and plumped pillows, the founders of Secret Linen Store could be forgiven for snoozing on the job.
As it is, they've been getting in to bed with their suppliers. The online retail business specialising in bedlinen has spent its maiden year busily building an attractive niche by dispatching only from manufacturer to consumer.
It is a business model used effectively by fast-growing furniture site Made.com and is also employed by Secret Linen Store's sister firm, Button & Sprung.
Adam Black is behind both beds businesses. The chirpy founder of discount furniture retail chain Feather & Black, which has 33 stores across the UK, set up Secret Linen Store a year ago before launching mattress specialist Button & Sprung this summer.
So why did Black trade the chain he built up since 2004, and which carries his name (along with that of co-founder Robbie Feather, now Sainsbury's online chief), for two digital start-ups?
"I had the right cards but was at the wrong table. For the last 20 years, the retailer has had the whip but now the supplier has more power," Black explains amid the airy surrounds of Button & Sprung's showroom opposite the River Café in Hammersmith. "I now have two hands of the right cards at the right table."
He adds that the secret behind the online linen store, of which he is non-executive chairman, is specialism: "If you sell lots of different products, you have to integrate supply chains. If you want to be the best at, say, cabinets you just do cabinets."
"I do not need showrooms up and down the country. I need to encourage you to come and see me at this showroom. It's a very different experience to the tired shops on every High Street and allows us to be significantly cheaper than High Street competitors."
Black's comments could be mistaken for an ill-judged pronouncement of the High Street's extinction, a death frequently foretold. However, he explains: "We are opening up a model of market that did not exist in the recession. With premium and discount performing so strongly in retail, you cannot get caught in the middle like Morrisons and Tesco have.
"Feather & Black has a discount model but it cannot be as cheap as Made.com. Marks & Spencer is caught between Primark and Asos at one end and the likes of Jigsaw. It's possible to survive, but you have to have a niche."
By cutting out the costs of running shops — from landlords to shop-floor staff — he is confident his business can outgun larger rivals including John Lewis, Heal's and The White Company in specific categories.
Retail runs in his veins as his family business, Peter Black, was once a general merchandise supplier to M&S. In a £280 million deal in 2000, it became one of the largest companies to go from public to private.
Helping Black achieve his vision are entrepreneurial sisters Molly Freshwater and Harriet Mears — both former Feather & Black employees and passionate about its product, which is sourced from the bedlinen mecca of northern Portugal.
Freshwater started out at The Iron Bed company in Nottingham, counting city peer and legendary designer Paul Smith as an inspiration, and Mears has significant experience in e-commerce and marketing. Both have built careers on forging strong links with manufacturers by paying them earlier than competitors, typically 40 days after the sale is made.
Freshwater describes the online shop as the realisation of a dream, and has set out with a clear vision to occupy the mid-market. Black explains that start-up capital for Secret Linen Store was raised "the Yorkshire way", favouring a retail, rather than dot-com, attitude featuring steady growth using small funds from relatively few investors.
As such, £50,000 of start-up capital was raised from shareholders including former Asos directors Jon Kamaluddin and Martin Strotton, and a photographer who has an equity stake in return for free photoshoots.
Over at Button & Sprung, Black has partnered with Matthew Hardcastle, the former boss of Sofa.com — another supplier-to-consumer business.
Black believes the showroom is in reach of "around 20 million chimney pots" — households — in the UK. Customers have driven from as far away as Scotland to visit the warehouse, which has an eye-watering near-100% conversion rate of visitors who go on to purchase from it.
Rolling around on its beds during our interview showed that the products stand the test. The bedlinen is of good quality while the mattresses' "pocket springs" prove a clever innovation. They allow for couples of different weights to have their preferred softness on their side of the mattress.
The technology has even caught the eye of sports retailer Intersport, which is poised to stock trainers using the springs. Black is also involved in a campaign by funding platform Kickstarter to launch Springuru trainers.
It's clear that Black and his team are instilled with plenty of fight to take on the High Street giants and, on current form, show few signs of being caught napping on the job.
Secret Linen Store
Founded: 2013
Staff: three
Turnover: £150,000
Business idol: Amazon founder Jeff Bezos — "He has an ability to challenge and disrupt the status quo, marrying great product value with industry-leading customer service. Difficult to deliver, and even more difficult to compete with."Reuse content


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Displaying the first of 6 photos of Boltongate.
Historic maps of Boltongate and the local area, hand-drawn by Ordnance Survey cartographers and Samuel Lewis.
Browse 35 photo books on Boltongate and the surrounding area.
My mother and father were married here in 1932 and I remember living here about 1036 or 7. The churchyard is full of my ancestors on both my mother's side and of my father's side, I also have many friends interred there and I think I am able to connect and recognise almost 90% of names of persons interred there. I now live in ...Read full memory
This is the place i took my new giirlfriend that i have been cheating on behind the back of my partner of seven years and mother to my two children. I am that selfish that i dumped my kids over easter took the family car and let my girlfriend drive it lied completely to both females ...Read full memory


text:
Solid west side Brick 4 Unit Cash Flows. Owner of over 30 years wants to divest. Newer roof, furnaces, AC and water heaters. Recently remodeled bathrooms. Separate gas and electric meters. Hardwood floors. Long Term Tenants who want to stay. Owner knows it is under rented. One Tenant has been there 30 years and receives discount for acting as on site manager. On bus line. Start or add to your Real Estate Portfolio.
Features Multi Family
|Total Number of Units: 4
|Year Built: 1959
|Total Lot Square Feet: 0
|Unit 1 Parking: 1 Space
|Taxes: $5,892
|School District: Madison Metropolitan
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Gutenberger is located in Lubeck. The hotel has 32 individually and very comfortably furnished single, double and family rooms. The restaurant has 100 seats and a smaller room is ideal for smaller groups, seminars or celebrations. It is the ideal place for your events, conferences, trainings or any...
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text: RT Video/DVD DB /z-wcorg/ DS http://worldcat.org ID 156999524 LA In Greek or dubbed Spanish dialogue, with optional English, French or Spanish subtitles; closed-captioned. T1 Iphigeneia A1 Cacoyannis, Michael., Papas, Irene., Kazakos, Kōstas., Karras, Kōstas,, Papamoschou, Tatiana., Euripides., Hellēniko Kentro Kinēmatographou., Twentieth Century Fox Home Entertainment, Inc., PB 20th Century Fox Home Entertainment PP Beverly Hills, Calif. YR 2007 AB Commander Agamemnon stands ready to launch his infamous thousand ships to retrieve the beautiful Helen of Troy. As the wind refuses to blow, a priest condemns him for sacrilege, and the powerful general is pressured to sacrific his daughter to save the states. Threatened and tormented, Agamemnon is faced with sending his child like a lamb to the slaugher and betraying his wife.


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Fall Intern - Talent Agency
The Mine Talent AgencyNew York, NY
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Part Time Unpaid Internship
Looking to get your foot in the door of the entertainment business? An essential first-step to a career in the industry is an internship at a great entertainment company.
The Mine is a busy bicoastal talent agency seeking 2 interns to start ASAP. During your time at The Mine, you will work side by side with our agents, learning the ins and outs of a talent agency as you work on some of the highest-profile Broadway and television projects. In addition to standard office work, interns will work closely with our clients and casting offices - setting up contracts, auditions, and commissions. We pride ourselves on providing our interns with a deep understanding of how the business functions and direct access to our entire team to make the experience worthwhile and educational.
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text:
While at NDC Oslo, K Scott and Jon talked to Chris Klug about pragmatically applying SOLID principles and on moving from Silverlight to HTML5.
Download / Listen: Herding Code 208: Chris Klug on SOLID principles and migrating from Silverlight to Angular and TypeScript
Show Notes:
Show Links:
Aug 21This entry was posted on Friday, August 21st, 2015 at 2:07 pmand is filed under podcast. You can follow any responses to this entry through the RSS 2.0 feed. You can leave a response, or trackback from your own site.


text:
Abigail Adams to Elbridge Gerry, 8 Jul. 1797
Philadelphia July 8 1797
Dear Sir
The president knowing how Sincere an interest I had taken in the result of your deliberations, communicated to me your Letter this morning received, and I do assure you Sir that it gave me great pleasure.
I had anticipated many of your reasons and arguments of a publick nature, and I did flatter myself that you would not decline so very important an Embassy, at so critical a State of our publick affairs. and I am not a little gratified to find the predictions of some, dissapointed by your acceptance.
Good people cannot always think alike. the votes which Stand recorded against your appointment gave me the more pain, because I know the gentlemen to be all Federal, and Sincerely to have the intent of their Country at Heart, but they entertaind an Idea, that having once taken an opinion, you would be so tenacious of it, as not to yeald, even when others might esteem it necessary by which means they feard the mission might be defeated.
There is this difference between those opposed to Judge Dana, and those who withheld votes from you. the latter, tho judging differently from the Executive will not abuse the Government, or calumniate its officers.
I could wish for the pleasure of seeing you before you left America, if it had comported with your plans. I see in the Centinal, a vessel up for Amsterdam. I therefore presume you will embark from Boston.
I feel most Sincerely for Mrs Gerry, I know by frequent experience how to sympathize with her. you have been witness to the bitterness of my Soul on similiar trials, before you was so well qualified to judge as a Husband and parent. from your Friendship and Sympathy I then derived Consolation, which I have never forgotten.
Mrs Gerry will deserve well of her Country for the Sacrifice She
so cheerfully> submits to.
That your Embassy may prove Successfull & honorable to yourself and Country, is the sincere / and Ardent wish of your / Friend and Humble Servant
A Adams
I take the Liberty to send you a late publication.


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Family Matters: Tackling the holiday season
We all know the big guy in the red suit who breaks into our homes this time of year, ever year. He parks a team of eight hoven creatures on our roof (probably trenching it with the sleigh rails) and comes down the chimney (whether we have one or not). He bites off the cookie, drinks the milk, and leaves half the cookie and the dirty milk glass for someone else to clean up. I hear he has been caught a time or two kissing the lady of the house. We put up with these antics because he supposedly puts stuff under the tree to make us all have a Merry Christmas.
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Identification of multiple integrin β1 homologs in zebrafish (
Integrins comprise a large family of α,β heterodimeric, transmembrane cell adhesion receptors that mediate diverse essential biological functions. Higher vertebrates possess a single β1 gene, and the β1 subunit associates with a large number of α subunits to form the major class of extracellular matrix (ECM) receptors. Despite the fact that the zebrafish (
Using RT-PCR, complete coding sequences of zebrafish β1 paralogs were obtained from zebrafish embryos or adult tissues. The results show that zebrafish possess two β1 paralogs (β1–1 and β1–2) that have a high degree of identity to other vertebrate β1 subunits. In addition, a third, more divergent, β1 paralog is present (β1–3), which may have altered ligand-binding properties. Zebrafish also have other divergent β1-like transcripts, which are C-terminally truncated forms lacking the transmembrane and cytoplasmic domains. Together with β1–3 these truncated forms comprise a novel group of β1 paralogs, all of which have a mutation in the ADMIDAS cation-binding site. Phylogenetic and genomic analyses indicate that the duplication that gave rise to β1–1 and β1–2 occurred after the divergence of the tetrapod and fish lineages, while a subsequent duplication of the ancestor of β1–2 may have given rise to β1–3 and an ancestral truncated paralog. A very recent tandem duplication of the truncated β1 paralogs appears to have taken place. The different zebrafish β1 paralogs have varied patterns of temporal expression during development. β1–1 and β1–2 are ubiquitously expressed in adult tissues, whereas the other β1 paralogs generally show more restricted patterns of expression.
Zebrafish have a large set of integrin β1 paralogs. β1–1 and β1–2 may share the roles of the solitary β1 subunit found in other vertebrates, whereas β1–3 and the truncated β1 paralogs may have acquired novel functions.
Integrins are a family of metazoan cell surface receptors that play critical roles in cell adhesion, migration, differentiation and survival
Integrin ligands include the major ECM components laminins, fibronectin and collagens. The β1 integrin sub-family contains 12 different heterodimers in mammals, which form the major group of cell-ECM receptors. An ECM-binding β chain is probably the most ancient, in evolutionary terms, of all the integrin β chains
Sequence analysis and X-ray crystal structures
Figure 1
Schematic diagram of the domain structure of integrin β subunits
Schematic diagram of the domain structure of integrin β subunits. Domain arrangement is based on crystal structures of the extracellular regions of α Vβ3 [13], α IIbβ3 [14] and β2 [15]. PSI, plexin/semaphorin/integrin; EGF, epidermal growth factor; TM, transmembrane. N-, amino terminus; C-, carboxyl terminus. Dotted line indicates the overall path of the polypeptide chain.
The A domain is the portion of the β subunit that is involved in extracellular ligand binding; this domain also is critical for the interactions with the α subunit that lead to heterodimerisation. The A domain consists of a central β-sheet encircled by seven α helices, and has two large sequence insertions compared to other A domains
X-ray crystal structures
The zebrafish is an emerging model organism with a large number of attractive features for studying the function of genes, such as: (i) the external and rapid development of embryos, (ii) the transparency of embryos, which allows visualisation and tracking of individual cells or groups of cells, (iii) the high degree of conservation between zebrafish and human genes, (iv) the similarities between human and zebrafish embryonic development resulting in a large proportion of tissues and organs being grossly similar between the two species, (v) its genetic tractability, aided by the availability of powerful genetic tools such as gene knock-down by morpholino-modified antisense oligonucleotides (morpholinos)
To date, our knowledge of the biological roles of integrins in vertebrates has been derived mainly from knockout studies in mice
Zebrafish have two β1 paralogs (β1–1 and β1–2) that are closely related to human β1
To amplify β1-like sequences, primers were designed based on partial sequences in the zebrafish genome project or from EST databases (see Methods). Complete coding sequences were amplified by RT-PCR using RNA from 4-day old embryos. Two of the sequences obtained, designated β1–1 and β1–2, had a high degree of identity to other vertebrate β1 sequences, such as human β1 [Genbank
Figure 2
Alignment of zebrafish β1 sequences (β1–1, β1–2, β1–3, β1tr-1, β1tr-2 and β1tr-3) with human β1
Alignment of zebrafish β1 sequences (β1–1, β1–2, β1–3, β1tr-1, β1tr-2 and β1tr-3) with human β1. The alignment was performed using ClustalW. Protein domains are annotated: PSI, plexin/semaphorin/integrin; EGF, epidermal growth factor; βTD, β terminal domain; TM transmembrane; cyto, cytoplasmic domain. MIDAS (M), ADMIDAS (A) and LIMBS (L) cation binding residues in the A domain are shown. Red underline indicates the position of the βB-βC loop, black underline indicates the position of the βD-α5 loop in the A domain. Sequence identities are indicated by *, conservative substitutions by :, semi-conservative substitutions by.
Figure 3
Domain comparison of zebrafish β1 paralogs β1–1 and β1–2 with human β1 (% sequence identity)
Domain comparison of zebrafish β1 paralogs β1–1 and β1–2 with human β1 (% sequence identity). PSI, plexin/semaphorin/integrin; EGF, epidermal growth factor; βTD, β terminal domain; TM+ cyto, transmembrane and cytoplasmic domains.
Zebrafish have a third β1 paralog (β1–3), which is more divergent in sequence from human β1
A third sequence amplified from zebrafish embryos, designated β1–3, was considerably more divergent in sequence from human β1 than β1–1 and β1–2 (Fig.
Table 1
Percentage amino acid identities between zebrafish and human β1 sequences
% id
Zebrafish have truncated β1 paralogs that are closely related to β1–3
Several zebrafish database partial EST sequences
Additional File 1
DNA sequence alignment of truncated β1 paralogs. TGA stop codon is shown in bold font. The portion of the 3'UTR used to design reverse primers is shown boxed. PolyA tail region is shown underlined. Sequence identities are indicated by *.
Click here for file
Table 2
Corresponding database entries for zebrafish β1 sequences
Accession Number
Gene Prediction
Genomic Location
Corresponding (or additional) EST
Source of EST
whole adult
gastrula stage
<72 h embryos
pooled gut
1 The complete sequence of ESTa was found to be 100% identical to that of
2 A partial sequence of this clone can be found under Genbank Accession number
3 The sequences of β1–2, β1–3 and ESTb are all contained within a single (inaccurate) gene prediction 2609 residues in length (genome project Zv5).
4 Latest version of genome project (Zv6).
5 Identical sequence in coding region but 3'UTR sequence appears to differ. Additional EST BG729583 (kidney).
6 Other ESTs: CO916860 (olfactory epithelium), CK865233 (testis), CN315944 (liver), CN171841 (kidney), CN320549 (liver).
Figure 4
Alignment of zebrafish truncated β1 sequences
Alignment of zebrafish truncated β1 sequences. The alignment was performed using ClustalW. Protein domains are annotated: PSI, plexin/semaphorin/integrin; EGF, epidermal growth factor. Yellow bar indicates the position of a putative flexible linker region in EGF-2 [15]. Domain boundaries in the EGF repeats are as predicted by Takagi
Figure 5
A. Domain comparison of zebrafish truncated β1 paralogs with human β1 (% sequence identity)
A. Domain comparison of zebrafish truncated β1 paralogs with human β1 (% sequence identity). B. Domain comparison of truncated β1 paralogs with β1–3 (% sequence identity). PSI, plexin/semaphorin/integrin; EGF, epidermal growth factor; βTD, β terminal domain; TM+ cyto, transmembrane and cytoplasmic domains. The sequence identities of the individual EGF repeats are shown in B.
All the truncated paralogs are closely related to β1–3 (Fig.
The truncated paralogs, like β1–3, have a substitution of two key aspartate residues by Ser/Asn at the ADMIDAS. In addition, these paralogs are also lacking an essential LIMBS residue (E189 in human β1 [E169 in the mature sequence]) due to a glutamate to arginine substitution. A similar mutation in human β1 (APM and J. Askari, unpublished data) or β3
Overall, the sequences of the A domains in the truncated paralogs are highly divergent from other chordate sequences; indeed, they are only slightly more similar to human β1 A domain (57–58% identity) than the Ciona β1 A domain (56% identity). The loops important for ligand binding and association with the α subunit are poorly conserved. For example, the truncated paralogs all have a large deletion of nine amino acids in the β B-βC loop. A second part of the α/β subunit interface involves residues in the βD-α5 loop, especially those that form a short stretch of 310 helix (DGKL)
Genomic and phylogenetic analysis reveals evolutionary relationships between the β1 paralogs
Gene sequences corresponding to β1–1, β1–2 and β1–3 can be identified in the zebrafish genome (Table
For phylogenetic analysis, the six zebrafish β1 sequences and two EST sequences were aligned with human β1 (see Fig.
Additional File 2
Protein sequence alignment of zebrafish β1 sequences with human and Ciona β1 orthologs. Alignment was performed using Clustal X and is displayed using Boxshader. Levels of sequence conservation are indicated (>50% identical, red; conservative substitutions, blue). Note that the refined Ciona β1 sequence
Click here for file
Figure 6
Phylogenetic relationship of zebrafish (Dr) β1 integrin chains with representative deuterostome orthologs
Phylogenetic relationship of zebrafish (Dr) β1 integrin chains with representative deuterostome orthologs. Maximum Likelihood tree is shown with supporting Neighbor Joining bootstrap replicates (black), Maximum Parsimony bootstrap replicates (blue) and Bayesian clade credibility values (brown). Horizontal scale is amino acid replacements per site.
The ML tree was supported by maximum parsimony and Bayesian analyses. Only neighbor joining analysis (not shown) produced two vertebrate clades where β1–1, β1–2 and human β1 grouped separately to the other sequences. However, the genomic locations of the different paralogs add support to the ML analysis. For example, the position of β1–2 and β1–3 in close proximity on the same scaffold suggests that β1–2 and β1–3 arose from a tandem duplication of a common ancestor. The presence of a truncated paralog in the same region of the genome adds weight to the proposal (supported by all the phylogenetic analyses) that the ancestor of the truncated paralogs arose from a duplication of the precursor of β1–3.
The divergent β1 paralogs are expressed later in development than β1–1 and β1–2
We examined the expression of the different β1 paralogs at different times of development using RT-PCR with primers specific for each paralog (Fig.
Figure 7
Expression profiling of zebrafish β1 paralogs during development
Expression profiling of zebrafish β1 paralogs during development. Expression of the different paralogs at 2, 4, 6, 8, 12, 14, 24, 48, 56, 72 and 96 hpf (hours post fertilization) was analyzed by semiquantitative RT-PCR using primers designed against a portion of extracellular domains of the different paralogs. The amplification of zebrafish β-actin was monitored as a positive control.
The divergent β1 paralogs are expressed less widely than β1–1 and β1–2
The expression of the different β1 paralogs in adult tissues was also examined by RT-PCR (Fig.
Figure 8
Expression profiling of zebrafish β1 paralogs in adult tissues
Expression profiling of zebrafish β1 paralogs in adult tissues. Expression of the different paralogs was analyzed by semiquantitative RT-PCR using primers designed against a portion of extracellular domains of the different paralogs. The amplification of zebrafish β-actin was monitored as a positive control. Br, brain; Fi, fin; Gi, gill; He, heart; In, intestine; Kd, kidney; Lv, liver; Mu, muscle; Sk, skin; Te, testis.
EST sequences corresponding to the different β1 paralogs can be identified in the NCBI databases (Table
The novel findings of this report are: (i) Extensive expansion of the β1 integrin gene family has taken place in zebrafish, (ii) a group of divergent β1 paralogs with regulatory site mutations is present, some of which are novel truncated forms that lack the transmembrane and intracellular domains, (iii) the different β1 paralogs exhibit varied patterns of temporal and tissue expression. Our findings raise several important questions. For example: Why do zebrafish have multiple versions of the single β1 gene found in higher vertebrates? What is the function of the divergent paralogs? Which α subunits does each paralog pair with?
Gene duplication is an important mechanism for the generation of phenotypic complexity, diversity and innovation. Gene duplication can occur either through tandem duplication of an individual gene, segmental duplication of a portion of a chromosome, or through whole genome duplication. Recent analyses have provided strong support for a whole genome duplication in the lineage of ray-finned fishes approx. 350 million years ago
In the classical model of gene duplication
In contrast to β1–1 and β1–2, it seems likely that the divergent β1 paralogs arose through tandem duplications. Taking the genomic, phylogenetic and sequence identity data together, the most likely scenario is that the precursor of β1–2 underwent a tandem duplication that gave rise to the ancestor of β1–3; a subsequent duplication of this paralog gave rise to the progenitor of the truncated paralogs. It seems likely that the divergent paralogs have acquired novel functions. With the exception of β1tr-3, these paralogs are expressed at later times of development and in a more tissue-restricted manner than β1–1 and β1–2. It therefore appears that the divergent paralogs may be involved in tissue differentiation, maintenance or remodelling, rather than in development/organogenesis. The expression of many of these paralogs in tissues such as liver and kidney supports this view.
One clue to the function of the divergent paralogs is that they possess a double substitution (DD to SN) in the regulatory ADMIDAS cation-binding site in the A-domain. Preliminary results suggest that engineering an identical substitution in human β1 (in a heterodimer with α5 subunit) produces a constitutively inactive integrin, i.e., an integrin with very low affinity for ligand (J. Askari and A.P. Mould, unpublished data). It is therefore possible that β1–3 could act as a dominant-negative β1 subunit by competing with β1–1 and β1–2 for α subunit partners or intracellular binding factors. It is also proposed that expression of high levels of unoccupied integrins can trigger apoptosis
It is also possible that the divergent paralogs could have acquired new binding partners. The very high degree of sequence conservation of the PSI, hybrid domain and EGF-1 between the divergent paralogs suggest that these domains form a key functional region of these polypeptides, and furthermore that the function of these domains is common to all the divergent β1 paralogs. Such a degree of conservation suggests that these domains interact with protein ligands (even though there is currently no evidence in other integrins that these domains have extracellular ligands). The PSI, hybrid, and EGF-1 domains lie adjacent to each other at, or close to, the knee region of the integrin
It is currently unclear how many separate genes are represented by the truncated β1 paralogs and ESTs. Although the sequences β1tr-1 and β1tr-2 are 98% identical to each other they are probably distinct gene products because they have different 3'UTRs. In addition, although β1tr-2 and β1tr-3 may have identical 3'UTR sequences, it appears unlikely that β1tr-3 is an alternatively spliced form of β1tr-2 because the differences between the two coding sequences are spread throughout the primary structures (Fig.
Truncated forms of β subunits have previously been reported in sponge and man
A key subject of future investigations will be to identify the α subunit partners of the different paralogs. All twelve α chains that pair with β1 in higher vertebrates have orthologs in the zebrafish genome, and at least two of these α chains have two co-orthologs (APM, unpublished results). It seems very unlikely that all of the β1 paralogs identified here are able to associate with all of the >14 potential α chain partners. For example, if each of the six β1 paralogs has retained the ability to pair with all of the α chains then a minimum of 84 different heterodimers could form. This would present a huge increase in complexity over the twelve heterodimers found in higher vertebrates. It is likely, therefore that in this process of multimeric protein evolution, previously termed 'molecular incest'
It is not yet clear if divergent β1 paralogs are found in other teleosts. Currently only limited gene information is available on other fish species, with the exception of the pufferfish
The presence of expanded gene families is hypothesized to have made a major contribution to the extraordinary diversity and evolutionary success of teleosts, which make up half of all vertebrate species. It is known that fish genomes are more 'plastic' than other vertebrate genomes, partly due to higher rates of gene duplication
At least six paralogs of the integrin β1 gene have been identified in zebrafish, demonstrating that this species has a greatly expanded integrin repertoire. Two of these paralogs may share the functions of the single β1 subunit found in higher vertebrates, whereas the remaining paralogs may have acquired novel roles. This is the first description of truncated β1 chains, which we speculate could be secreted proteins that act as regulators of integrin functions.
Sequencing of zebrafish integrin β1 paralogs
The complete amino acid sequence of human β1 [Swiss-Prot:
Total RNA was prepared from 4-day old embryos using TRI reagent (Sigma), and reverse transcription was performed using Superscript II (Invitrogen) according to the manufacturer's instructions. PCR reactions were performed using Phusion (New England Biolabs). Cycling parameters were 98°C for 30 s, followed by 40 cycles of 98°C for 10 s, 60°C for 20 s and 72°C for 60 s. An additional sequence, β1tr-3, was amplified from reverse transcribed RNA from adult kidney (prepared as described below) using the same primers as for β1tr-2. The PCR reactions generated products of ~2.4 kB for β1–1, β1–2 and β1–3, and ~1.9 kB for β1tr-1, β1tr-2 and β1tr-3. EST clones ESTa and ESTb were obtained from RZPD German Resource Center for Genome Research, product numbers IRAKp961B08165Q [IMAGE:6525557] from adult kidney cDNA library and IMAGp998I1214695Q3 [IMAGE:7001749] from whole adult body cDNA library, respectively.
PCR products were analysed on 1.5% agarose gels. Sequencing of PCR products or EST clones was performed using the BigDye cycle sequencing kit (Applied Biosystems). PCR products from reactions using the 5'-ATGGATATAACAGTTTTGTTATTATCAG-3' forward primer contained a mixture of sequences and therefore these products were subcloned into the Zero Blunt TOPO cloning kit (Invitrogen). Sequencing of individual clones revealed a single most abundant sequence (β1tr-1, β1tr-2 or β1tr-3). Alignment of zebrafish and human sequences was performed using CLUSTAL W
Phylogenetic analysis
The β1 integrin sequences identified in
RT-PCR analysis
Embryos were harvested at different times post fertilization. Tissues from adult fish (~9 months old) were removed by dissection and flash frozen in liquid nitrogen. Total RNA was prepared using Trizol (QIAGEN). Reverse transcription was performed using M-MLV reverse transcriptase or Omniscript (Invitrogen) according to the manufacturer's instructions. PCR reactions were performed using recombinant Taq (a gift from P. Walker, University of Manchester, UK) or Advantage 2 polymerase (BD Biosciences). For the truncated β1 sequences, primers were designed to give a single product of approx. 600 bp that is unique to β1tr-1, β1tr-2 or β1tr-3. The following primers were used:
β1–1 5'-ATGGACCTGAAGCTACTTTTCATATC-3' and 5'-GTGACGTTTCTCCAGCCAATGTG β1–2 5'-GATGGTAATGAATGCACCAAGGC-3' and 5'-GGAGTCGGAGGTAAGCGTTCC-3' β1–3 5'-GTGTTGTTTGATATAGAAATCACGGCT-3' and 5'-CGTATCCCACTTGGCATTATTTTTCTC-3' β1tr-1 5'-CCAGGATCTGGATGCATACTG-3' and 5'-ATGTATAACATGAGGTCATGATGTAC-3' β1tr-2 5'-CCAGGATCTGGATGCATACTG-3' and 5'-GTATAACATGTGTCTCAATATATGATG-3' β1tr-3 5'-CATGATGAGGTGCTGGCGGATG-3' and 5'-GTATAACATGTGTCTCAATATATGATG-3'
Cycling parameters were 95°C for 2 min, followed by 30 cycles of 95°C for 30 s, 60°C for 20 s and 72°C for 60 s. PCR products were analysed on 1.5% agarose gels. The identity of selected products was confirmed by DNA sequencing. As a control, a fragment of β-actin was amplified using the primers 5'-CCACGAGACCACCTTCAACT-3' and 5'-CATTGTGAGGAGGGCAAAGT-3' for 28 cycles of 95°C for 30 s, 55°C for 40 s and 72°C for 60 s. Negative controls consisted of no cDNA template reactions.
Authors' contributions
APM and MJH conceived of the study. APM and JAM carried out the database searching, PCR reactions and sequence analysis, JHJ performed the phylogenetic analyses and ACG prepared RNA for RT-PCR analysis, APM and ACG carried out the RT-PCR analysis. All authors participated in the interpretation of data and/or in the writing of the manuscript.
JHJ and ACG are supported by BBSRC PhD studentships, AJLH by a fellowship from Cancer Research UK, and APM and MJH by The Wellcome Trust. We thank Paul Walker for the gift of recombinant Taq, and Drs Sally Stringer, Paul Walker and Patrick Buckley for helpful discussions.
Integrins: Bidirectional, allosteric signaling machines
Integrin signaling to the actin cytoskeleton
Integrins and cell proliferation: regulation of cyclin-dependent kinases via cytoplasmic-signalling pathways
Integrin regulation
Regulation of integrin function through conformational complexity: not simply a knee-jerk reaction?
The three-dimensional structure of integrins and their ligands, and conformational regulation of cell adhesion
Molecular evolution of integrins: Genes encoding integrin β subunits from a coral and a sponge
The integrins of the urochordate
Consequences of lack of β1 integrin gene expression in mice
Deletion of β1 integrins in mice results in inner cell mass failure and peri-implantation lethality
β1 integrin function in vivo: adhesion, migration and more
Integrins in regulation of tissue development and function
Crystal structure of the extracellular segment of integrin αVβ3
Structural basis for allostery in integrins and binding to fibrinogen-mimetic therapeutics
The crystal structure of the plexin-semaphorin-integrin domain/hybrid domain/I-EGF1 segment from the human integrin β2 subunit at 1.8Å resolution
A structure prediction for the ligand-binding region of the integrin β subunit: evidence for the presence of a von Willebrand factor A domain
Changing ligand specificities of αvβ1 and αvβ3 integrins by swapping a short diverse sequence of the β subunit
Identification of a region in the integrin β3 subunit that confers ligand binding specificity
The role of the specificity-determining loop of the integrin β subunit I-like domain in autonomous expression, association with the α subunit, and ligand binding
Role of ADMIDAS cation-binding sites in ligand recognition by integrin α5β1
Bistable regulation of integrin adhesiveness by a bipolar metal ion cluster
Conformational changes in the integrin β A domain provide a mechanism for signal transduction via hybrid domain movement
Breaking the integrin hinge. A defined structural constraint regulates integrin signaling
The molecular basis of filamin binding to integrins and competition with talin
Effective targeted gene 'knockdown' in zebrafish
Target-selected inactivation of the zebrafish rag1 gene
Making waves in cancer research: new models in the zebrafish
In vivo drug discovery in the zebrafish
Integrin-dependent pathologies
In vivo functions of integrins: lessons from null mutations in mice
Functional consequences of integrin gene mutations in mice
Molecular characterization and leukocyte distribution of a teleost β1 integrin molecule
Identification of critical residues for ligand binding in the integrin β3 I-domain by site-directed mutagenesis
Genome duplication in the teleost fish Tetraodon nigroviridis reveals the early vertebrate proto-karyotype
From 2R to 3R: evidence for a fish-specific genome duplication (FSGD)
Fugu genome analysis provides evidence for a whole-genome duplication early during the evolution of ray-finned fishes
Subfunction partitioning, the teleost radiation and the annotation of the human genome
Integrin evolution: insights from ascidian and teleost fish genomes
A pair of Sox: distinct and overlapping functions of zebrafish sox9 co-orthologs in craniofacial and pectoral fin development
Duplicate mitf genes in zebrafish: Complementary expression and conservation of melanogenic potential
Apoptosis of adherent cells by recruitment of caspase-8 to unligated integrins
Identification of a natural soluble form of the vascular endothelial growth factor receptor, FLT-1, and its heterodimerization with KDR
Normal human fibroblasts produce membrane-bound and soluble isoforms of FGFR-1
Interleukin 1 receptor antagonist. A new member of the interleukin 1 family
A new alternative transcript encodes a 60 kDa truncated form of integrin β3
Generation of a minimal α5β1 integrin-Fc fragment
Fibrillar collagen: the key to vertebrate evolution? A tale of molecular incest
Genome duplication, a trait shared by 22000 species of ray-finned fish
Evolution and diversity of fish genomes
Extensive expansion of the claudin gene family in the teleost fish,
Many genes in fish have species-specific asymmetric rates of molecular evolution
Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
The ClustalX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools
PHYLIP (Phylogenetic Analysis Using Parsimony)
Likelihood-mapping: a simple method to visual phylogenetic content of a sequence alignment
MrBayes: Bayesian inference of phylogeny
Definition of EGF-like, closely interacting modules that bear activation epitopes in integrin β subunits


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3 bedroom mediterranean-style villa with private pool and BBQ in Denia, Costa Blanca. This property is very close to the beautiful town of a Denia and from here you can be downtown in less than a 10 minute drive, or to visit other lovely towns such as Javea or Benissa. Moreover, this town is located 1 hour to Alicante Airport and less than 45 minute drive to Alicante city. This property comprises of, a large outside terrace, leading onto the pool. Inside there is a large lounge with a fireplace and a fitted open kitchen. There are three spacious double bedrooms and two large full bathrooms. One of the bedrooms has beautiful panoramic views to Denia and the sea. Outside there is also a private swimming pool, a shower room, a built in BBQ with a lovely tiled table and the separate garage.
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Home › Forums › Campfire › Post-Trip Reports › sierra high country snow levels
Jul 16, 2007 at 5:59 pm #1224150
Greg JenningsMember
Anyone just back from the sierras have a snow and/or mosquito report? I'll be traveling over several 11K passes next week and am wondering if I need to lug my ice axe along. In a normal year I would take it, but with the low snow pack…I'm just not sure.Jul 16, 2007 at 9:04 pm #1395622
Shawn BasilMember
@bearpawLocale: Southeast
I just had to abort my JMT thru-hike due to a stress fracture in my left ankle. However, up to 11K, there was NO snow on the trail between Yosemite Valley and Red's Meadow. The word from north-bound PCT'ers is that there is no appreciable snow on the entire High Sierra corridor from Whitney to Vermillion Valley Resort. What little there was a couple of weeks ago (patches you could walk across easily) are likely gone by now.
Mosquitoes were a nuisance despite the scarcity of snow, but not a terror.
However, be VERY aware of wildfire concerns. There were 4 separate fires in the Inyo National Forest when I got off the trail. It seems like the eastern California corridor is a huge patchwork of flames and dry lightning storms are only making things worse. Be informed and be careful.Jul 16, 2007 at 9:05 pm #1395623
Steven NelsonBPL Member
@slnsfLocale: Northern California
We just did the High Passes Loop in Yosemite and Ansel Adams Wilderness 6/30-7/4, and other than a few dozen yards of snow near Red Peak Pass (11.1K'), there was no snow on the trails and passes – just on some shaded exposures of higher peaks.
Mosquitoes, on the other hand, were ferocious in the lower areas.Jul 16, 2007 at 9:06 pm #1395624
Aaron SorensenBPL Member
@awsorensenLocale: South of Forester Pass
Hey Greg,
I just got back last weekend.
I hiked with a few PCT'ers for a few days from Reds Meadow to Tuolumne Meadows.
They only hit a few small patches of snow going over Muir Pass, and that was it, the least amount of snow they had ever seen.
The only time they got wet way crossing Evolution Creek which was about a foot deep.
Everything else was just stepping stones to cross.
Mosquitoes were thinning out as well.
I was up there two weeks before that and they were a lot thicker.
I wouldn't take the ice ax but might want to take some poles if you are going to be off the main trails.
I dought at only 11k that you'll even hit any patches of snow.Jul 17, 2007 at 9:41 am #1395662
This is amazing considering it is only mid July and some of these reports are several days old. I hiked from Kennedy Mdws to Monanche Mdws in mid April, a time when the meadows are lush with run-off or still completely covered in snow. Except for the Kern, there was no water between Kennedy Mdws and Monanche Mdws and the meadows were handpan dry with yellow, dry grass. The Kern was low enough to cross hopping the rocks across-normally in flood stage that time of year.
In May in Cottonwood Lakes just below the basin the Southfork Creek should have been in flood but was low and water temp relatively warm and the meadows were dry without mud or marsh and the grass burnt dry. I just can't imagine what it will be like in late August.Jul 18, 2007 at 6:40 pm #1395842
Greg JenningsMember
I appreciate the beta. The ice axe will stay at home. Sorry to hear about your ankle injury, Shawn. Best of luck with a speedy recovery!
I'm off tomorrow and very much looking forward to it. It has been many years since I've had the time to hike up there.Jul 18, 2007 at 9:00 pm #1395866
Ken HelwigBPL Member
@kennyhel77Locale: Scotts Valley CA via San Jose, CA
Enjoy your hike. Snow is not a concern and mosquitos are only a problem in lower elevations..and even that is starting to leave. Have fun!!
You must be logged in to reply to this topic.


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Wednesday 27th July 2011
On Saturday 6th August brilliant Dutch label Rush Hour will be taking over Cable, bringing with them a stellar line up that mixes Chicago and Detroit legends alongside up and coming talent. Virgo Four will be playing their last ever live set together in the UK, Rick 'The Godson' Wilhite will be no doubt living up to his nickname, whilst Tom Trago (live), Cosmin TRG and BNJMN (live) represent the new breed. Boiler Room's 'Live From' sessions were a natural extension from their Live Show, and they now stream from events all over the world. This is the first time Boiler Room have broadcast live from Cable – so whether you're watching live from home or dancing down the front – don't miss it.


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