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The temperature of the debate was turned up yesterday by Hong Kong's Financial Secretary, Sir Hamish Macleod, who said the authorities would press ahead with the colony's dollars 20.3bn ( pounds 13.6bn) new airport despite failure to agree financing plans with the Chinese. The Legislative Council, given the choice of mothballing the project or injecting enough finance to allow the next round of contracts to be awarded, appeared to be favouring the latter option, he said.
Sir Hamish added that he hoped the Chinese, who have hampered the project for nearly two years, would begin to talk once they realised it gave them no leverage over other issues. 'It hasn't affected the political talks one inch,' he told Reuters news agency.
At the weekend, however, a senior Chinese trade official warned that Britain's trade would not remain unaffected by political differences over Hong Kong. 'Bilateral economic and trade relations can hardly escape damage from an unco-operative and unfriendly Britain,' Tong Jiemin, deputy director- general of European affairs at the Trade Ministry, told the official China Daily. Such an implied threat has not been heard for nearly a year, and comes when France is seeking to repair relations with Peking.
The French government, which a year ago agreed to sell Taiwan 60 Mirage fighters worth pounds 1.3bn, last week issued a joint statement with China in which it promised not to sell any more weapons to the island, and reaffirmed that it recognised Peking's claim to Taiwan. The Chinese Foreign Minister, Qian Qichen, will meet the French Prime Minister, Edouard Balladur, in Paris next week, and Mr Balladur will visit China in March. According to political sources in Paris, the sight of Chancellor Helmut Kohl returning to Germany last November with nearly pounds 2bn worth of contracts convinced the French that they could no longer afford to be frozen out of the Chinese market.
'We appreciate that we are a bit more isolated as a result of the French decision,' said a British source, 'but despite all that has happened in the past year or more, there is still no sign of discrimination against British business.'
Last month, after seven months of talks ended in stalemate, Mr Patten introduced the first part of his political reform. In his meetings with John Major and the Foreign Secretary, Douglas Hurd, this week he is expected to discuss the shape and timing of the second part, which is likely to be far more controversial since it deals with the crucial 1995 Legislative Council election. China has already threatened to reverse Mr Patten's reforms when it takes over in Hong Kong, but appears to be holding its fire until it sees his next move.
Britain is likely to feel the brunt of Peking's assertiveness, because the Chinese appear to have changed tack in dealing with the US. President Jiang Zemin is said to have told a congressional delegation at the weekend that China would 'make an effort' to meet Washington's concerns on human rights.
Peking had apparently misinterpreted the US desire for more contact as a signal that its human rights policy was purely for domestic consumption. The Secretary of State, Warren Christopher, will repeat his message to Mr Qian in Paris next week: without clear progress on this issue, China cannot expect its 'most favoured nation' trading privileges to be renewed later this year. Peking, which relies on its huge trade surplus with the US to sustain its economic boom, now appears to be heeding these warnings.
Asia's Great Game, page 16
- More about:
- Beijing
- China
- Hong Kong (chn)
- Taiwan


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Show some love for Valentine's Day or whenever a little warmth is in order with this brilliant pink cubic zirconia and preciosa crystal heart belly button ring. The prong set CZ, row of crystals along the curved heart, and solitary sparkling drop give the dangling navel ring glamour to spare.
Home $1.99 Body Jewelry Pink Cubic Zirconia Elegant Curved Heart Dangle Belly Ring

subset: commoncrawl


text:
Less than 1% of us have specialty licenses plates, the lowest rate in the country. So when the state decided to try to increase that figure, it looked for a private company to help out. Enter My Plates-dot-com. There are 27 designs, three for motorcycles.
Kim Drummond says until now you had to renew your plates every year. At My Plates you can buy a plate for one, five or ten years.
"If you want only one year it begins at 95-dollars but there's a greater value in going for a longer term. If you get that same plate for ten years it comes out to 40-dollars a year."
That's for the specialty plate with a random number and letter combination. There are two higher price levels that depend on how much you want to personalize the plates. The top price is the luxury level for ten years at 795-dollars.
Drummond says each specialty request has to pass two tests.
"Anytime someone applies for a personalized license plate it goes through a process first to see if it's taken, and secondly to make sure it is something that is appropriate for publication and that is up to TXDOT."
You can see and select plates at My Plates-dot-com.


text:
Product Info
This one of a kind oversized bag is handwoven with beautiful tan and olive fabric that has been reinforced with interface for support. There is a pretty tan fringe added and is fully lined inside with two pockets, zipper closure and strap with a 12 inch drop length. Bag measures 9X14X7. Scotch guarded.
Shipping and Return
7 day return


text:
Keep your piano in tune longer!
The Grand Piano Humidity Control SystemThe Piano Life Saver System
The Grand Piano Humidity Control SystemThe Piano Life Saver System
is silent and installed out-of-sight inside your piano. Each Piano Life Saver System carries a 5-Year Guarantee which can only be activated by having the System installed by a piano technician.Grand Piano Installation
Dehumidifier: when humidity levels rise, it distributes moisture away from your piano using warm air currents.
Humidifier: moisturizes the dry wood of your piano when the humidity drops; a low water warning light indicates when the Humidifier needs additional water; refilling the Humidifier is simple and easy.
Watering Tube: allows you to provide water to the Humidifier when the yellow light on the 3-Light LED Panel indicates a need for water.
Humidistat: this is the brain of the System which senses whether the wooden parts of your piano are too moist or too dry and automatically switches the System to function as a Dehumidifier or Humidifier to protect your piano from damage caused by changes in humidity.
3-Light LED Panel: features a green light marked POWER to indicate the System has electrical power and a yellow light marked WATER which blinks when the Humidifier needs water. If the System includes the optional Smart Bracket on the Humidifier tank, the red light marked PADS will blink when the pads are no longer wicking water, indicating they should be replaced.
The Piano Life Saver System as seen from beneath a Grand Piano
Hoyt Taylor © 2014 All Rights Reserved


text:
When shopping for a paintball gun, you may feel overwhelmed at the many different choices available. For those who are unfamiliar with this type of equipment, it can be helpful to read online reviews of different guns in your price range to find the best one. If this is your first purchase of a paintball gun, going to a store that sells different brands and styles can be beneficial, especially if you have the opportunity to speak with an employee who is knowledgeable about the different options.
What to Look for in A Quality Paintball Gun
Most importantly, you should find a gun that you feel comfortable holding. This is why it's helpful to shop in a physical store where you can hold the guns to see which one you like best. It's also important to find one that is made of quality materials and is designed to last. Some cheaper guns are made of low-quality plastics that won't stand up to much use before they start to malfunction or even break while you're trying to use them. When looking at a paintball gun, check all the moving parts to ensure that they are easy to maneuver. You should also ensure that your choice can hold enough ammo without needing frequent refills of paint balls.
Playing paintball can be a great way to relieve stress and spend some time with your friends. Even those on a budget can find a good paintball gun but it may take some shopping around and some research to get the most out of your money. Reading online reviews from those who have purchased the guns you're considering can help you find one that is ideal for your specific needs.


text:
At Rickover Naval Academy our vision encompasses an atmosphere that cultivates academic excellence, trust, and student leadership. We will motivate students to excel through both individual cadet and platoon academic honors.
Applying to Military Academies is easy! For more general FAQs for CPS rules and requirements to attend a CPS Military Academy, please see CPS: Access and Enrollment: Access and Enrollment: Military page at http://www.cps.edu/AccessAndEnrollment/Pages/Military.aspx
Our Counseling Center provides academic guidance, college and career counseling, and social and emotional support and guidance for all Rickover cadets.
ASVAB Testing at Rickover


text:
John D. Clements, Ph.D.
Research Interests
Recently, a great deal of effort has been directed towards replacement of existing whole cell or formalin inactivated vaccines with subunit vaccines that may be safer and more effective than existing vaccines. Still other efforts are directed at developing alternatives to traditional vaccine delivery, including mucosal and transcutaneous delivery.
Mucosally and transcutaneously delivered vaccines offer a number of potential advantages over traditional vaccines including 1) the potential to confer mucosal as well as systemic immunity, 2) increased stability, 3) increased shelf-life, and 4) elimination of needles and the need for specially trained healthcare specialists to administer vaccines.
Dr. Clements's Vaccine Research Laboratory is developing powerful new techniques for vaccination against bacterial, viral, and parasitic diseases, including novel adjuvants (substances that enhance the immune response to foreign antigens) and delivery systems (nanocarriers for vaccine delivery).
View Select Publications
John D. Clements, Ph.D.
1430 Tulane Ave, New Orleans, LA 70112 504-988-5150 firstname.lastname@example.com


text:
|Publication number
|Publication type
|Application number
|Publication date
|Dec 14, 1999
|Filing date
|Mar 26, 1998
|Priority date
|Mar 26, 1998
|Fee status
|Also published as
|Publication number
|Richard Anthony Bongiovanni, Peter Andrew Barnett, Douglas Ellwood Shultz
|Original Assignee
|Northrop Grumman Corporation
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (81), Non-Patent Citations (10), Referenced by (43), Classifications (13), Legal Events (7)
|External Links: USPTO, USPTO Assignment, Espacenet
The present invention relates generally to medical devices utilized to isolate and treat intensive care patients outside of a medical facility, and more particularly, to a self-contained, transportable isolation and environmental protection system utilized in the resuscitation, stabilization, and transport of medical patients that further facilitates the isolation of the trauma casualty from a contaminated environment or a contaminated patient from a clean environment.
Typically, when a person is injured and becomes a casualty in a contaminated environment, such as occurs in a chemical warfare confrontation, the casualty is taken to a decontamination site where he is decontaminated, and thereafter transferred to a medical treatment facility. In many cases, it is imperative that medical treatment be given to the casualty immediately.
However, in order to administer treatment, the casualty must first be isolated and transported into an enclosure within which medical personnel may work on the casualty or additional means must be provided for allowing access to the casualty without introducing contaminants into the enclosure containing the casualty. In this regard, it is desirable to isolate the patient from the environment when the environment-contains substances which may be detrimental to the medical patient. For example, if the patient has suffered severe blood loss or is experiencing difficulty breathing, then it is desirable to prevent the patient from breathing dust, engine exhaust, smoke, etc. It is also desirable to isolate the medical patient from the environment when bacteriological, chemical and/or radiological hazards are present, as may occur during battlefield conditions.
In addition, it would be advantageous if such isolated environment were caused to facilitate the removal of such toxic and infectious residues that may be present on the clothing and/or skin of such isolated medical patient to thus enable the patient to become further stabilized during transit to a suitable medical facility. Ideally, the isolated medical patient would be contained within an environment that is provided with air that is constantly circulated, decontaminated and refreshed such that such toxic and infectious residues are rapidly removed from the isolated medical patient's containment area.
Alternatively, it is desirable to isolate the caregivers from the medical patient in instances where the medical patient is suspected of having a contagious disease, or has been exposed to bacteriological, chemical or radiological contamination. As such, it is desirable to provide means for isolating the patient from the environment and caregivers, as well as isolating the caregivers from the patient.
Unfortunately, prior art apparatuses currently available for isolating and treating the casualty in the field are generally ineffective in providing an environment conducive to the administration of medical treatment, and can thus cause treatment to be delayed until the casualty is transported to an adequate medical facility, which is frequently not readily accessible. Such prior art apparatuses are further generally deficient in providing an environment where the casualty is protected from contaminants, and provided with refreshed, decontaminated air that actually facilitates the removal of contaminants already present on the skin and/or clothes of the casualty, in addition to providing trauma casualty treatment.
As such, there is a need in the art for an isolation system within which a medical patient is placed at the battlefield and within which the medical patient remains isolated until a suitable medical facility can be accessed. It is further desirable to provide an isolation system that can protect a medical patient contained therewithin from an contaminated external environment such that the condition of such patient is not made worse by the ingress of poisonous substances resulting from chemical and/or biological attack, as well as other harsh and extreme weather conditions arising from rain, wind, dust, hot, cold, wet and dry climatic conditions. There is still further a need for an isolation system that is capable of delivering a constant supply of air to a patient contained therewithin wherein such air is constantly circulated, decontaminated, refreshed, and selectively attemporated, that is further capable of delivering such air in a manner that facilitates rapid removal of toxic and infectious residues present upon the patient, and subsequently filters and decontaminates the same. There is additionally a need for a medical patient isolation system that is specifically designed and configured to function integrally with conventional litters and certain life support systems utilized therewith, most notable of the latter being the Life Support for Trauma And Transport device developed by Northrop Grumman Corporation and disclosed and claimed in co-pending U.S. Pat. application Ser. No. 08/687,693.
The present invention specifically addresses and alleviates the above-mentioned deficiencies associated with the prior art. More particularly, the present invention comprises a self-contained isolation and environmental protection system for the transportation of a patient from the battlefield or a scene of an accident to a hospital. The system comprises the combination of a patient containment enclosure and environmental control system (ECS) that are designed and configured to interconnect with a conventional litter and life support system utilized therewith, and in particular Northrop Grumman's Life Support for Trauma and Transport (LSTAT), such that there is delivered to the patient a constant supply of circulated, decontaminated and refreshed air that is prevents the further contamination of the patient or caregivers while facilitating trauma treatment.
The ECS is designed and configured to take air from the surroundings, extract contaminated particles and gas from the air by filtration, and force the resultant purified air to the patient, via the containment enclosure. The ECS is further designed to attemporate the air provided to the containment enclosure, and may further include an environmental conditioning unit that conditions, namely heats, cools, and/or dehumidifies the air as may be desired. In this regard, the environment conditioning unit is preferably coupled to an environment sensor that can selectively control environmental conditions. There is further preferably provided a filter to remove biological, chemical, and radiological contamination from the breathing air, once expelled.
The containment enclosure of the ECS preferably comprises a covering positionable about the casualty or medical patient when the latter assumes a supine position upon the litter with which the system of the present invention is used. The containment enclosure comprises the combination of a first lower bag portion and a second upper bag portion that are designed and configured to mate with one another via a long zippered opening to form an airtight, an anti-leak chamber. Formed about the upper bag portion are a series of tubular gas passages designed and configured to receive pressurized gas from the ECS such that when the tubular gas passages are filled with a pressurized gas supplied thereby, the upper bag portion assumes a semi-rigid, parallel piped structure.
Formed upon the interior of such tubular passageways are a plurality of apertures oriented to deliver a constant stream of air to the patient contained therewithin. In a preferred embodiment, the plurality of apertures are so formed upon the tubular structures of the cover such that as air is delivered, it is washed over the patient in a head-to-toe direction such that rapid removal of toxic and infectious residues is facilitated. To facilitate the passage of air through the chamber in such a manner, there is formed upon one end of the bag an outlet or exhaust valve designed to draw air delivered into the bag out therefrom in a proximal to distal direction.
The containment enclosure component of the system of the present invention is preferably fabricated from chemical and/or biochemical resistive materials that are further capable of protecting a patient contained therewithin from harsh and extreme weather conditions arising from rain, wind, dust, hot, cold, wet and dry climatic conditions. The bag component is further preferably fabricated from a transparent material to enable the patient contained therewithin to be viewed by medical personnel, as well as to minimize patient claustrophobic experiences. To facilitate medical treatment, the containment enclosure may further preferably provided with patient access means, preferably in the form of a flexible hand sock-type portals mounted upon the containment enclosure that is strategically positioned for complete patient access. Ideally, such portal system is designed to be left hand/right hand independent and designed to maximize the provider's hand manipulative abilities and finger functioning dexterity. The enclosure component of the system of the present invention is further preferably configured to assume a small, compact space when collapsed so that the same may be easily stored and transported, but may be readily deployed when necessary to form a closure about a patient.
It is therefore an object of the present invention to provide an isolation and environmental protection system for protecting a patient from a toxic or infectious environment, and protecting the caregiver from a contaminated patient, while facilitating the use of a life support system, namely the LSTAT, to perform trauma care, that further provides the patient with filtered, decontaminated air that may be selectively attemporated or conditioned to desired parameters.
Another object of the present invention is to provide an isolation and environmental protection system for protecting a patient from a toxic or infectious environment that is capable of delivering refreshed air to the patient contained therewithin.
Another object of the present invention to provide an isolation and environmental protection system for protecting a patient from a toxic or infectious environment that further protects the patient against harsh and extreme weather conditions arising from rain, wind, dust, hot, cold, wet and dry climatic conditions.
Another object of the present invention is to provide an isolation and environmental protection system for protecting a patient from a toxic or infectious environment that facilitates the rapid removal of toxic and infectious residues present upon the person contained therein.
Another object of the present invention is to provide an isolation and environmental protection system for protecting a patient from a toxic or infectious environment wherein such system is self-contained and specifically designed and configured to accommodate, fit within and be carried by a variety of military transport vehicles and aircraft.
Another object of the present invention is to provide an isolation and environmental protection system for protecting a patient from a toxic or infectious environment that allows a patient contained therewithin to be viewed by medical personnel and allow such medical personnel to quickly and easily access the patient's body when contained and enclosed therein.
A still further object of the present invention is to provide an isolation and environmental protection system for protecting a patient from a toxic or infectious environment wherein such system is simple to operate, may be readily utilized, and is sufficiently durable to withstand harsh environmental and/or battlefield conditions.
These, as well as other features of the present invention, will be more apparent from the following description and drawings. It is understood that changes in the specific structure shown and described may be made within the scope of the claims without departing from the spirit of the invention.
FIG. 1 is a perspective view of a containment enclosure and ECS constructed in accordance with a preferred embodiment of the present invention shown in a pre-packaged, collapsed configuration contained within a transportable life support system in combination with a life support stretcher;
FIG. 2 is a perspective view of a patient assuming a supine position upon the litter with the containment enclosure and ECS of the present invention being deployed thereabout;
FIG. 3 is a perspective view of the patient of FIG. 2 fully contained within the containment enclosure of the present invention having a secondary component of the ECS shown coupled therewith;
FIG. 4 is a rear perspective view of the patient, containment enclosure, and life support system of FIG. 3, wherein there is further depicted an ECS shown coupled to said containment enclosure;
FIG. 5 is a perspective view of the containment enclosure of the present invention indicating the flow of air delivered within the interior portion thereof as distributed by tubular gas passages formed thereon;
FIG. 6 is a perspective view of a portion of the tubular gas passageway formed upon the containment enclosure of the present invention depicting a plurality of apertures through which is shown the direction of a flow of air; and
FIG. 7 is a schematic diagram of the components of the environmental conditioning system integrated into the isolation and environmental protection system of the present invention.
The description set forth below in connection with the appended drawings is intended as a description of the presently preferred embodiment of the invention, and is not intended to represent the only form in which the present invention may be constructed or utilized. The description sets forth the functions and the sequence of steps for constructing and operating the invention in connection with the illustrated embodiment. It is to be understood, however, that the same or equivalent functions may be accomplished by different embodiments that are also intended to be encompassed within the spirit and scope of the invention.
Although discussed and illustrated herein as having particular application in battlefield situations, those skilled in the art will appreciate that the containment enclosure of the present invention may be utilized in various different civilian applications, such as emergency rescue and medical evacuation, especially where the emission or production of poisonous gasses or particles contaminate the surrounding and where people in or close to the area of the emergency or catastrophe require immediate degassification and treatment. As such, the terms medical patient, patient and casualty as used herein are defined to include patients and/or victims of any accident and/or medical condition resulting in the need for emergency medical care.
Referring now to the drawings, and initially to FIG. 1, there is shown a self-contained isolation and environmental protection system 10 comprised of the combination of a life support stretcher or litter 12 and a patent containment enclosure and environmental control system 11 connectible therewith for the transportation of a patient from the battlefield or a scene of an accident to a hospital. In this regard, it is contemplated that the system 10 of the present invention is specifically designed to configure to the utilized with certain battlefield life support systems, and in particular, the Life Support Trauma and Transport System (LSTAT) developed by Northrop Grumman Corporation, as disclosed and claimed in co-pending patent application Ser. No. 08/667,693, the teachings of which are expressly incorporated herein by reference.
As shown, the litter 12 is configured to have a proximal end 12a and a distal end 12b and an upper platform surface 20 upon which a medical patient may be placed, usually in a supine position. The external configuration of the litter 12 is further preferably designed to fit within and be carried by a variety of military transport vehicles and aircraft such as UH-60 Blackhawk helicopter, the UH-1 Huey helicopter, the HMMWV, the C-130 winged aircraft and/or the C141 fixed wing aircraft. Such configuration is further compatible with standard NATO litter mounts such that the system 10 of the present invention may simply be carried aboard such military evacuation vehicles in the same manner that a standard NATO stretcher having a battlefield casualty disposed thereupon is carried. To facilitate the transport of such litter 12, the same is typically provided with retention members 34 extending from the proximal and distal ends thereof.
The ECS 11, which is attachable to the litter 12 component of the system 10 of the present invention, is designed to take air from the surroundings, extract contaminated particles and gas from the air by filtration, and compress and force the resultant purified air into an enclosure formed about the patient via the bag component 14 thereof, discussed more fully below. The various components comprising the ECS 11, shown schematically in FIG. 7, advantageously provide means for maintaining a selectively controlled environment independent of the external surroundings. Such selectively controlled environment, as provided and maintained by the ECS, and more particularly the components thereof discussed more fully below, is further designed to provide filtered and decontaminated air to the patient ventilator enclosed within the system should the patient require the same. To provide means for selectively controlling the ECS 11, a control circuit 22 is provided and is coupled to such system to thus enable the user to regulate the operation thereof.
Mounted upon the litter 12, and preferably formed as a component of the ECS 11 is an containment enclosure 14 constructed in accordance to a preferred embodiment of the present invention. The containment enclosure 14 is preferably designed and configured to assume a first collapsed, packaged configuration, as shown, and preferably is packaged within the ECS 11 (as shown in phantom) via strap 16. The containment enclosure 14 is fabricated from those materials resistive to chemical and/or biological attack, namely, poisonous gasses or lethal bacterial agents used in the battlefield, or in the unintentional emission of poisonous substances. The containment enclosure 14 is further fabricated from those materials well-known in the art that can withstand harsh and extreme weather conditions arising from rain, wind, dust, hot, cold, wet and dry climatic conditions. It will be further appreciated that such containment enclosure 14 will preferably be fabricated from transparent materials so that in use, the patient 36 contained therein, depicted in FIGS. 3 and 4, may be visually observed by medical personnel. Additionally, by providing a transparent containment enclosure 14, the patient 36 contained therein is less likely to experience a claustrophobic event insofar as such individual will be able to see his or her surroundings.
Referring now to FIG. 2, there is shown the containment enclosure 14 as deployed over a casualty 36, the latter assuming a supine position upon the platform surface 20 of the litter 12. As illustrated, the containment enclosure 14 is comprised of two parts, namely, a lower bag portion 14b and an upper bag portion 14a. Both bag portions 14a, 14b are extended from the proximal end 12a of the litter 12 in the direction indicated by the letter A. As will be appreciated, in order for the casualty 36 to assume such position within the containment enclosure 14, it will first be necessary to extend the lower bag portion 14b upon the platform surface 20 with the upper bag portion 14a then being extended over the patient 36 toward the distal end of the litter to form a canopy over the patient 36.
To enable the upper and lower bag portions 14a, 14b to form an air-tight seal with one another, there is formed about the respective peripheral edges thereof respective sets of teeth 18, 38 that cooperate to form a leak-proof, zipper-like closure. In this respect, the containment enclosure 14 is provided with a slide fastener 20 that, when advanced in the direction indicated by the letter B about the patient, causes the respective teeth 18, 38 to mate with one another and form the air-tight seal 44 shown in FIG. 3.
As additionally shown as a detached component of the system 10 of the present invention there is preferably provided a second component 26 of the ECS 11 which is designed to be mounted upon litter 12, and more particularly the distal end 12b thereof, that is designed and adapted to interconnect with inlet hose 29 and outlet hose 42 via dedicated ports, such as 26a. The secondary component 26 is further provided with an outlet valve 32 designed and adapted to interconnect with valve 30 formed on the distal end 12c of the litter 12 to facilitate the recirculation of air delivered to the patient 36, discussed more fully below.
The containment enclosure 14 is further provided with a bezel 52, shown in FIG. 4, to which air inlet nozzle 28 interconnects therewith. As will be recognized by those skilled in the art, air inlet nozzle 28 is coupled with the control circuit 22 to thus enable the latter, either automatically or by user control, to direct the flow of air passing therethrough and into the containment enclosure 14.
Referring now to FIG. 3, the containment enclosure 14, and more particularly the upper bag portion 14a thereof, is shown in an inflated state. In this respect, horizontal peripheral edge 46 and ribs 48 extending therefrom are formed as tubular gas passages formed by flexible inner tubes conformably connected to one another which are encased within the material of the upper bag portion 14a. Such material may be formed out of a flexible plastic material which may be either heat sealed or sewn around the tubular portions 46, 48, and is preferably formed of a material which is impermeable to any contaminates which are expected to be found in the environment in which the containment enclosure 14 are to be used. In an alternative embodiment, the tubular gas passages 46, 48 are formed integrally with the upper bag portion 14a.
As illustrated in FIG. 5, air is caused to be passed through the tubular passageways 46, 48 via a duct, which preferably takes the form of a bezel connection 52. As will be recognized by those skilled in the art, the gas passages 46, 48 are coupled to the bezel 52 in such a manner that air passing through bezel connection 52 causes such passageways to become inflated to form a semi-rigid structure that defines a chamber or capsule 50 that isolates the medical patient 36.
The air is ultimately delivered radially inward about the chamber 50 defined by the inflated containment enclosure 14, as indicated by the letter C. As shown in greater detail in FIG. 6, the path of air 54 that is passed about horizontal peripheral tubular passageway 46 flows upwardly through lofting support rib passageway 48 and eventually flows through a plurality of apertures 56 formed thereon. As those skilled in the art will appreciate, such inward radial flow of air about the chamber 50 causes the patient contained therewithin to be thoroughly washed with such refreshed air. Furthermore, air pressure contained within the lofting air passages creates an outwardly supporting structural framework for the patient enclosure.
Once the air has been washed about the patient 36, the same is recycled by the ECS, via outlet hose 42 or the like connection formed on the distal end of the containment enclosure 14. In this regard, outlet hose 42 is connectable to an exhaust port formed upon the secondary component 26 of the ECS 11, the latter being coupled with a fan situated within the ECS to thus draw air from the proximal end of the containment enclosure 14 to the distal end thereof, shown as the direction D in FIG. 5, and discussed more fully with respect to FIG. 7.
By directing the air forced into the chamber 50 to be drawn from the proximal end to the distal end thereof thus causes the same to wash over the patient in a head-to-toe flow direction. As those skilled in the art will appreciate, air washing over the contaminated patient in such a manner advantageously provides chemical drying for rapid removal of toxic residues on clothing and skin which, once removed from the chamber 50 and into the outlet hose 42 and valve 32 of the ECS 11, are filtered and decontaminated through an air recycle system of the ECS 11. Moreover, bathing the patient in air in such a manner eliminates dead air pockets and CO2 buildup which thus facilitates uniform heating, cooling and humidity control.
Referring now to FIG. 7, there is shown the various components comprising the ECS 11 of the present invention and their respective interconnection to one another to provide and maintain a selectively controllable environment to a given patient 36 isolated therewithin. As will be recognized, the various components shown in FIG. 7 may preferably be either partially or completely integrated into the life support stretcher 12 and beneath the upper platform surface 20 upon which the patient 36 is ideally positioned. Additionally, as illustrated in FIGS. 2 and 3, certain components, and in particular, secondary component 26 of the ECS 11, may be selectively attachable directly upon the upper platform surface 20.
As illustrated, the ECS 11 includes a particle separator 60 into which air is drawn in, via fan 64 from the external environment and filters the same to remove contaminating particles therefrom. Disposed intermediate the filter 60 and fan 64 is a check valve 62 which selectively controls the rate of air passing therebetween. The air received by fan 64 is then routed to either one of two directions, namely, either to ventilator subsystem 66 or to air pump 80, the latter causing the air received thereby to be passed through one of two heat exchangers, 82, 84 which are provided to either heat or cool the air passing therethrough. Thereafter, the air is then fed through inlet hose 29, also depicted in FIGS. 2, 3, and 5 for recirculation to the patient 36. In this respect, the air is fed to inlet hose 29 via the secondary component 26 of the ECS 11, as shown in FIGS. 2 and 3, is caused to distribute about the tubular passageways 46, 48 formed about the enclosure.
Alternatively, all or a portion of the air flowing from fan 64 may be fed to a ventilator subsystem 66. In this regard, as such ventilator subsystem may preferably take the form of those ventilator subsystems disclosed in co-pending U.S. Pat. application Ser. No. 08/687,693. From such ventilator 66, the air is then caused to pass into the containment enclosure 14, via the tubular passageways 46, 48 thereof. In this respect, it should be recognized that the air flowing from the ventilator subsystem 66 into the tubular passageway 46, 48 will be accomplished via the connection between the air inlet valve 28 and bezel 52 formed upon the containment enclosure 14, as depicted in FIG. 4.
Once the air is distributed about the patient as described with reference to FIG. 5, the same is then extracted through outlet hose 42. In this regard, air is drawn from the outlet hose 42 via a second fan 70. The air drawn therethrough is caused to pass through a second filter 68 which advantageously filters and removes contaminating particles present upon the person contained within the enclosure 14. Air received by the fan 70 may then either be expelled, through check valve 72 or, alternatively, may be fed to a de-humidifier 74 which may remove excess moisture 76 from the air that is recirculated through the system. The air may then be fed through another check valve 78, provided to control the rate of air passing therethrough, and then passed into air pump 80 for recirculation within the containment enclosure 14.
As discussed above, the air provided by both inlet valve 28 and inlet hose 29 is radially delivered to the patient 36 contained within containment enclosure component 14. Such delivery causes the bag 14 to inflate and form chamber 50 such that air is washed over the patient 36. As will be recognized, such delivery of air to the patient 36 causes the containment enclosure component 14 to be positively pressurized, i.e., pressure above ambient, which advantageously isolates the patient 36 from caregivers and/or the environment. Such positive pressurization causes air to leak therefrom, which is selectively controlled by the outlet valve 72 of the ECS 11. Advantageously, by filtering and treating the air both as it delivered to and withdrawn from the chamber within which the patient 36 is isolated, such patient 36 is protected from the external, contaminated environment. Likewise, the caregivers are protected in such situations where the patient 36 is contaminated insofar as any toxic substances or contagions that would remove from or otherwise be expelled by the patient 36 is filtered and isolated via second filter 68, such that the caregivers are not subjected to the same.
As will be recognized, each of the components comprising the ECS 11 will be coupled to a control circuit integral to the ECS (not shown) that will regulate the operation thereof. To prevent over-heating of the components comprising the ECS system 11 during operation thereof, there may further preferably be provided a cooling air system (not shown) designed to circulated cooled air within the litter 12 when the ECS 11 is in use. Such system 11 may further be coupled to an environment sensor (not shown) to sense and/or regulate environmental conditions within the patient containment area. Such conditions may include temperature, light, pressure, humidity, as well as other environmental conditions. Thus, for example, environmental sensor may be operative to sense chemical and/or bacterial conditions within the housing, and to implement air filtration functions to deplete any chemical, biological contaminants. In this respect, such air filtration functions are normally implemented on a continuous basis in order to assure that the environmental conditions within the housing remain isolated from environmental conditions external to the housing.
With respect to operation of the system 10 of the present invention, such operation comprises the steps of removing the containment enclosure 14 from its collapsed, packaged condition and charging the bottom portion of the containment enclosure 14 across the litter 12, and attaching the bezel 52, being an integral part thereof, to the patient circuit interface 22 of the life support stretcher 12, the latter providing access to the ventilator subsystem 66 via inlet valve 28. The patient is then positioned thereupon. As will be recognized, to the extent additional medical devices, tubes, wiring and the like are to be deployed, the same are passed into the containment enclosure opening, through the bezel 52 and from the patient circuit interface 22 and connected to the patient positioned thereupon.
Thereafter, the fastening device 20 is slid about the peripheral edges of the upper and lower bag portions to form an air-tight seal. Environmental and decontamination systems contained within the ECS 11 are then activated with air being purified and passed from the ECS 11 to the containment enclosure by way of the tubular passageways 46, 48 thereof. Air will thus flow over the patient in the head-to-toe manner discussed above.
While in such isolated state, the patient may be transported via conventional means and, upon arrival at a suitable medical facility, may be treated as necessary. To that end, the ECS 11 need only be turned off and the sealable closure opened to thus gain access to the patient. Although not shown, the containment enclosure 14 of the present invention may further be provided with patient access means, which may comprise a flexible hand sock-type portal which is formed upon the containment enclosure 14 and strategically position for complete patient access. Such portal system, as those skilled in the art will appreciate, is preferably designed to be left hand/right hand independent and designed to maximize the care provider's hand manipulative abilities and finger functioning dexterity. Following use of the containment enclosure 14, the same may be discarded or, alternatively, decontaminated, sterilized and repackaged for reuse.
Although the invention has been described herein with specific reference to a presently preferred embodiment thereof, it will be appreciated by those skilled in the art that various additions, modifications, deletions and alterations may be made to such preferred embodiment without departing from the spirit and scope of the invention. Accordingly, it is intended that all reasonably foreseeable additions, modifications, deletions and alterations be included within the scope of the invention as defined in the following claims.
|Cited Patent
|Filing date
|Publication date
|Apr 21, 1916
|Oct 10, 1916
|Wm G Hesse & Son Mfg Co Inc
|Ambulance-trailer body.
|Apr 18, 1917
|Feb 12, 1918
|Robert S Freedman
|Cot or stretcher.
|Apr 23, 1917
|Mar 12, 1918
|Emma Miller
|Nov 1, 1917
|Dec 17, 1918
|Frank Hugo Brand
|Combined army supply-truck and ambulance.
|Jun 19, 1916
|Nov 13, 1923
|Westinghouse Electric & Mfg Co
|Three-phase reactance coil
|Dec 11, 1943
|May 28, 1946
|Goodrich Co B F
|Inflatable protective container
|Feb 11, 1952
|Mar 29, 1955
|Theodore Konecny
|Multiple purpose amphibious military trailer vehicle
|Nov 19, 1956
|Jun 10, 1958
|Kern James W
|Folding trailers
|Jul 19, 1960
|Aug 21, 1962
|Mansen Carl H
|Folding trailer
|Apr 5, 1962
|Sep 15, 1964
|Lovercheck Charles L
|Ambulance trailer
|Oct 1, 1965
|Oct 24, 1967
|Shindler Harry A
|Carriers, particularly for victims of high energy radiation
|Apr 7, 1966
|Apr 2, 1968
|Exterior Products Inc
|Convertible trailer and supporting post therefor
|Feb 23, 1968
|Jan 27, 1970
|Nachtigall Walter E Jr
|Vehicle body
|Apr 11, 1968
|Sep 29, 1970
|Cyril E Nissen
|House trailer
|Sep 19, 1969
|Jul 25, 1972
|American Sterilizer Co
|Portable isolator
|Apr 1, 1971
|Apr 24, 1973
|Miller D
|Emergency inflatable recompression unit
|Jul 17, 1972
|Oct 2, 1973
|Besler H
|Oxygen bottle carrier particularly for stretchers
|Mar 30, 1972
|Dec 4, 1973
|Rf Inc
|Inflatable aquatic rescue board and method of rescue
|Sep 13, 1972
|Oct 8, 1974
|Inst For Ind Res & Standards
|Construction of stabilised platform
|Sep 24, 1973
|May 17, 1977
|Infranor S.A.
|Nuclear accident carrier
|Nov 17, 1975
|Nov 29, 1977
|Survival Technology, Inc.
|Heart-lung resuscitator litter unit
|Nov 23, 1977
|Jul 17, 1979
|Airborne Life Support Systems, Inc.
|Life support chamber for infants, method and system
|May 31, 1979
|Sep 30, 1980
|Vickers Limited
|Transit isolator
|Jan 30, 1980
|Sep 7, 1982
|The Eisenhauer Manufacturing Company
|Stretcher and litter combination
|May 4, 1981
|Oct 5, 1982
|Arthur Kaufman
|Portable life support system
|Sep 14, 1981
|Jan 17, 1984
|Star Leon D
|Mobile hospital unit
|Oct 24, 1983
|Dec 4, 1984
|Calspan Corporation
|Method and apparatus for evacuating contaminated casualties
|Dec 20, 1984
|Apr 29, 1986
|Rosemarie Stith
|Life support stretcher bed
|Aug 22, 1985
|Jul 14, 1987
|Joerns Healthcare, Inc.
|Bedside control module for healthcare stations and the like
|Sep 26, 1986
|Dec 29, 1987
|Marquette Electronics, Inc.
|Patient monitoring system having transportable data module and display unit
|Jun 26, 1985
|Feb 16, 1988
|Stephen Rafelson
|Vital sign modular unit
|Nov 2, 1984
|May 31, 1988
|Penox Technologies, Inc.
|Medical device transporter
|Nov 7, 1986
|Jul 19, 1988
|Clark Gerald W
|Infant restraining device
|Feb 24, 1987
|Sep 6, 1988
|Beney Daniel R
|Self contained, mobile intensive care bed structure
|Oct 20, 1987
|Nov 1, 1988
|Harrison Mildred B
|Hospital bed
|Jul 31, 1987
|Nov 8, 1988
|Bucalo Frank J
|Critical care equipment transport system for an ambulance stretcher
|Jul 5, 1988
|Sep 18, 1990
|Arizona Technology Development Corporation
|Mobile intensive care patient handling system apparatus and method of using
|Aug 16, 1988
|Jan 1, 1991
|Pfohl Robert L
|Vital signs monitoring and communication system
|Mar 30, 1990
|Apr 9, 1991
|Massachusetts Eye And Ear Infirmary
|Patient transporter
|Mar 23, 1990
|May 21, 1991
|Linda Rebar
|Integral stretcher and intravenous fluid carrier/gravity dependent drainage support
|Feb 20, 1990
|Jun 4, 1991
|Calspan Corporation
|Casualty wrap with integral medical access chamber
|Sep 27, 1989
|Jul 23, 1991
|Process First, Inc.
|Apparatus for and method of manufacturing preforms
|May 29, 1990
|Sep 24, 1991
|Murphy Wendy J
|Patient evacuation envelope
|Sep 7, 1990
|Nov 12, 1991
|Comitato Nazionale Per La Ricerca E Per Lo Sviluppo Dell'energia Nucleare E Delle Energie Alternative
|Protective device, individual, portable, with total insulation and controlled atmosphere
|Sep 4, 1990
|Jan 7, 1992
|Hill-Rom Company, Inc.
|Hospital bed and assemblies of hospital care apparatus
|May 19, 1989
|Feb 4, 1992
|Societe Louit Sa
|Self-contained module for intensive care and resuscitation
|May 7, 1991
|Mar 3, 1992
|Ferno-Washington, Inc.
|Automatically adaptable fastening system for wheeled cots and similar devices
|May 8, 1990
|May 12, 1992
|Capintec, Inc.
|Ambulatory physiological evaluation system including cardiac monitoring
|May 16, 1990
|Jun 2, 1992
|Hill-Rom Company, Inc.
|Care cart and transport system
|Dec 10, 1990
|Jun 16, 1992
|Lifeport, Inc.
|Emergency support device with flexible polyethylene sheet
|Jul 19, 1991
|Dec 22, 1992
|Wellman Machinery Of Michigan, Inc.
|Method of making reinforced structural composite assemblies
|May 13, 1991
|Jul 20, 1993
|Wellman Machinery Of Michigan, Inc.
|Apparatus and method for applying multiple type fibers to a foraminous surface
|Jul 26, 1991
|Aug 17, 1993
|Theradynamics Corporation
|Entryway system for mobile medical unit
|Nov 2, 1992
|Apr 26, 1994
|Jesse Terry A
|Rescue toboggan
|Jul 7, 1992
|May 3, 1994
|Jacob Segalowitz
|Wireless electrocardiographic and monitoring system and wireless electrode assemblies for same
|Jul 30, 1992
|Jul 19, 1994
|Crawford Jr John M
|Medical monitor system
|Oct 8, 1992
|Jul 26, 1994
|Ab Ventilatorverken
|Ventilation method and means for the same
|Jul 13, 1992
|Aug 9, 1994
|Hill-Rom Company, Inc.
|Ventilator and care cart each capable of nesting within and docking with a hospital bed base
|Nov 12, 1992
|Aug 16, 1994
|Ticom Corporation
|Method of making reinforced structural composite assemblies and assembly produced thereby
|Mar 8, 1993
|Aug 30, 1994
|Brian Koria
|Antiseptic containment for biohazardous material
|Jun 4, 1993
|Apr 11, 1995
|Telectronics Pacing Systems, Inc.
|Leadless implantable sensor assembly and a cardiac emergency warning alarm
|Apr 29, 1993
|Jun 6, 1995
|The United States Of America As Represented By The Secretary Of The Navy
|Compact, portable critical care unit for hyperbaric and recompression chambers
|May 25, 1993
|Aug 15, 1995
|David; Daniel
|Ambulatory patient health monitoring techniques utilizing interactive visual communication
|Jun 24, 1992
|Dec 12, 1995
|Cardiac Science, Inc.
|Automatic external cardioverter/defibrillator
|Sep 14, 1994
|Feb 27, 1996
|Cardi-Act, L.L.C.
|Patient-transport apparatus
|Jun 21, 1994
|Mar 12, 1996
|Hill-Rom Company, Inc.
|Ventilator and care cart each capable of nesting within and docking with a hospital bed base
|Oct 28, 1994
|Apr 30, 1996
|Segalowitz; Jacob
|Device-system and method for monitoring multiple physiological parameters (MMPP) continuously and simultaneously
|May 12, 1995
|Nov 5, 1996
|Williamson; Theodore A.
|Medical patient transport and care apparatus
|Apr 7, 1994
|Jan 7, 1997
|Tremont Medical
|Personal health care system
|Aug 22, 1995
|Apr 1, 1997
|Kabushiki Kaisha Toshiba
|Medical bed system
|Mar 7, 1996
|May 6, 1997
|The United States Of America As Represented By The Secretary Of The Army
|Transportable life support system
|Aug 4, 1995
|May 20, 1997
|Hill-Rom, Inc.
|Bed with a plurality of air therapy devices, having control modules and an electrical communication network
|May 3, 1996
|Sep 9, 1997
|Kinetic Concepts, Inc.
|Patient interface system
|Aug 3, 1995
|Oct 28, 1997
|Hill-Rom, Inc.
|Hospital bed with user care apparatus
|Aug 6, 1996
|Nov 18, 1997
|Tremont Medical, Inc.
|Patient monitoring system with chassis mounted or remotely operable modules and portable computer
|Apr 9, 1997
|Dec 29, 1998
|Atom Medical Corporation
|Title not available
|May 19, 1989
|Nov 23, 1989
|Societe Louit S.A.
|Autonomous module for intensiv care and reanimation
|Title not available
|Title not available
|Aug 7, 1995
|Feb 15, 1996
|Buchanan Aircraft Corporation Limited
|Portable intensive care unit
|Aeromed Systems, Inc. Specification/AMT 300.
|Aeromed Systems, Inc.--Specification/AMT 300.
|Buchanan Aircraft Corporation Engineered Composites (M.I.R.F.) Mobile Intensive Care Rescue Facility.
|MOBI The Intensive Care Unit.
|Mobile Intensive Care Rescue Facility (MIRF).
|MOBI--The Intensive Care Unit.
|Spectrum Aeromed Above and Beyond 1995.
|Spectrum Aeromed--Above and Beyond 1995.
|The Results of Innovation Lifeport, Inc.
|The Results of Innovation--Lifeport, Inc.
|Citing Patent
|Filing date
|Publication date
|Jul 16, 1999
|Jun 5, 2001
|Isovac Products Llc
|Isolation apparatus
|Jun 30, 1999
|Sep 11, 2001
|Patient monitor
|Dec 14, 2000
|Jun 25, 2002
|Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of National Defence Of Her Majesty's Canadian Government
|Field-deployable forced air warming system
|Feb 12, 2001
|Jul 16, 2002
|The United States Of America As Represented By The Secretary Of The Army
|Convertible patient isolation pod
|Aug 3, 2000
|Nov 25, 2003
|Sequal Technologies, Inc.
|Portable oxygen concentration system and method of using the same
|Nov 5, 1999
|Sep 13, 2005
|Kci Licensing, Inc.
|Patient cooling enclosure
|Feb 11, 2002
|Apr 18, 2006
|Kendro Laboratory Products, Gmbh
|Process for humidifying the useful space in an incubator and in a controlled atmosphere incubator
|Feb 6, 2004
|Nov 21, 2006
|Walling Jeffrey L
|Protective bed unit
|Mar 29, 2004
|Jan 27, 2009
|Gustafson Martin K
|Bio-hazard attack family survival dome
|Jun 23, 2006
|Nov 24, 2009
|Steris Inc.
|Integrated decontamination/aeration system for vehicles
|Dec 18, 2006
|Mar 16, 2010
|Hill-Rom Services, Inc.
|Patient point-of-care computer system
|Oct 9, 2009
|Oct 12, 2010
|Steris, Inc.
|Integrated decontamination/aeration system for vehicles
|Apr 8, 2009
|Oct 26, 2010
|Kci Licensing, Inc.
|Patient cooling enclosure
|Nov 9, 2007
|Oct 26, 2010
|Integrated Medical Systems, Inc.
|Foldable, portable trauma treatment and monitoring patient platform
|Feb 23, 2010
|Mar 22, 2011
|Hill-Rom Services, Inc.
|Hospital bed computer system
|Nov 9, 2007
|Oct 11, 2011
|Todd Douglas Kneale
|Modular transportable life support device
|May 7, 2002
|Aug 21, 2012
|The United States Of America As Represented By The Secretary Of The Army
|Convertible patient isolation pod
|Dec 20, 2011
|Dec 18, 2012
|Hill-Rom Services, Inc.
|Touch screen control of a hospital bed
|Mar 16, 2011
|Feb 5, 2013
|Hill-Rom Services, Inc.
|Hospital bed computer system with pharmacy interaction
|Aug 26, 2008
|Apr 2, 2013
|Koninklijke Philips Electronics N.V.
|Mobile multiple modality containment suite
|Dec 30, 2008
|Aug 20, 2013
|Sikorsky Aircraft Corporation
|Engine air particle separator
|Apr 7, 2011
|Dec 31, 2013
|Hill-Rom Services, Inc.
|Patient support, communication, and computing apparatus including movement of the support and connection to the hospital network
|Jan 10, 2013
|Mar 18, 2014
|Hill-Rom Services, Inc.
|Hospital bed computer system for control of patient room environment
|Oct 8, 2013
|May 13, 2014
|Warren N. Root
|Portable expandable fire protection chamber
|Dec 19, 2013
|Feb 2, 2016
|Hill-Rom Services, Inc.
|Patient support, communication, and computing apparatus
|Mar 14, 2013
|Jan 10, 2017
|Hill-Rom Services, Inc.
|Control system for patient support apparatus
|Feb 11, 2002
|Aug 15, 2002
|Heiko Reinhardt
|Process for humidifying the useful space in an incubator and in a controlled atmosphere incubator
|May 7, 2002
|Sep 19, 2002
|Paschal Charles R.
|Convertible patient isolation pod
|Feb 6, 2004
|Aug 19, 2004
|Walling Jeffrey L.
|Protective bed unit
|Oct 14, 2003
|Oct 28, 2004
|Bridges John H.
|Anthrax remediation and response
|May 10, 2004
|Jan 6, 2005
|Alion Science And Technology
|Collapsible, protective containment device
|May 20, 2004
|Apr 21, 2005
|Yuen Chi Yee M.
|Protective means and apparatus
|Feb 28, 2006
|Jul 6, 2006
|Kendro Laboratory Products, Gmbh
|Process for humidifying the useful space in an incubator and in a controlled atmosphere incubator
|Jun 23, 2006
|Dec 28, 2006
|Steris Inc.
|Integrated decontamination/aeration system for vehicles
|Nov 9, 2007
|May 14, 2009
|Todd Douglas Kneale
|Modular transportable life support device
|Apr 8, 2009
|Aug 27, 2009
|Kci Licensing, Inc.
|Patient Cooling Enclosure
|Oct 9, 2009
|Feb 11, 2010
|Steris Inc.
|Integrated decontamination/aeration system for vehicles
|Aug 26, 2008
|Aug 26, 2010
|Koninklijke Philips Electronics N.V.
|Mobile multiple modality containment suite
|Jan 17, 2007
|Oct 28, 2010
|Lockheed Martin Corp.
|Vehicular mounted interior nuclear, chemical & biological protection
|Dec 5, 2001
|Jun 19, 2002
|Her Majesty the Queen as represented by the Minister of National Defence
|Field-deployable stretcher with forced air warming system
|Sep 7, 2004
|Apr 20, 2005
|Chi Yee Michael Yuen
|Protective means and apparatus
|Feb 12, 2001
|Jan 24, 2002
|James R Gauger
|Convertible patient isolation pod
|Nov 4, 2015
|Aug 4, 2016
|Comunale Mark E
|Disposable bio-secure environmental unit
|U.S. Classification
|600/21, 5/629
|International Classification
|Cooperative Classification
|European Classification
|Mar 25, 1998
Owner name: NORTHROP GRUMMAN CORPORATION, CALIFORNIA
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text: About Amarantus BioScience, Inc.Amarantus BioScience, Inc. is a development-stage biotechnology company founded in January 2008. The Company has a focus on developing certain biologics surrounding the intellectual property and proprietary technologies it owns to treat and/or diagnose Parkinson's disease, Traumatic Brain Injury and other human diseases. The Company owns the intellectual property rights to a therapeutic protein known as Mesencephalic-Astrocyte-derived Neurotrophic Factor ("MANF") and is developing MANF-based products as treatments for brain disorders. The Company also is a Founding Member of the Coalition for Concussion Treatment (#C4CT), a movement initiated in collaboration with Brewer Sports International seeking to raise awareness of new treatments in development for concussions and nervous-system disorders. For further information please visit www.Amarantus.com. About Banyan Biomarkers Banyan Biomarkers is the leader in developing in vitro diagnostic products to address unmet clinical needs for the detection of traumatic brain injury. The Company is focused on developing a simple point-of-care blood test that will be used by physicians to detect the presence and severity of brain trauma and improve the medical management of head injured patients. Banyan Biomarkers has a licensing agreement with the University of Florida for exclusive global use of technology related to this product. To learn more about Banyan Biomarkers, Inc., visit http://www.banyanbio.com. Forward Looking Statements This press release contains forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Such statements include, but are not limited to, statements about the possible benefits of MANF therapeutic applications and/or advantages presented by Amarantus' PhenoGuard technology, as well as statements about expectations, plans and prospects of the development of Amarantus' new product candidates. These forward-looking statements are subject to a number of risks, uncertainties and assumptions, including the risks that the anticipated benefits of the therapeutic drug candidates or discovery platforms, as well as the risks, uncertainties and assumptions relating to the development of Amarantus' new product candidates, including those identified under "Risk Factors" in Amarantus' most recently filed Annual Report on Form 10-K and Quarterly Report on Form 10-Q and in other filings Amarantus periodically makes with the SEC. Actual results may differ materially from those contemplated by these forward-looking statements Amarantus does not undertake to update any of these forward-looking statements to reflect a change in its views or events or circumstances that occur after the date of this presentation.


text:
Weigh in video for Substance Combat 1.0 that takes place in Toronto, Ontario on Saturday June 29, 2013. watch video >>
http://fightnetwork.com - Fight Network previews GLORY 10 Los Angeles set to take place September 28, 2013 in Ontario, CA. featuring Robin van Roosmalen (29-5) vs. Shemsi Beqiri (72-8) in a 70kg bout watch video >>
Hardrock MMA 48 Preview of the Rematch Braedon Ward vs Branden Bishop. Rematch to take place June 23, 2012 in Louisville, KY tickets available at http://www.HardrockFight.com watch video >>
Friday June 22nd come and witness this stacked MMA Fight card featuring Vern Earwood VS Josh Copeland, much talked about female rivalry Tori Adams VS Raquel Pennington, and main event Brian Seraiah W watch video >>
http://fightnetwork.com/ - Fight Network recaps GLORY 17 Los Angeles preliminary action from June 21, 2014 in Inglewood, CA. featuring Gabriel Varga winning the 65kg contender tourney after dispatchi watch video >>
Andreas Georgiou and Roberto Reid preview GLORY 22: Lille, which takes place Friday, June 5 from the Stade-Pierre-Mauroy in Lille, France. In the main event, Dutch kickboxer Rico Verhoeven defends h watch video >>
http://fightnetwork.com/ - Fight Network presents Hard Knocks Fighting 44 LIVE on June 26 at 12 a.m. ET from Calgary, AB. featuring Nick Ring vs. Corey Devela For additional coverage of MMA, boxing watch video >>
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http://fightnetwork.com/ - Fight Network Canada & International presents RFA 38 LIVE featuring Thiago Moises vs. Jamal Emmers on June 3, 2016 at The Hangar at O.C. Fairgrounds in Costa Mesa Californi watch video >>
Weigh in highlights from the inaugural Macto Championships set for June 27 featuring the main event of Nick Osipczak vs. Kyle Redfearn and Alex Montagnani vs. David Round, plus Dean Amasinger vs. Dan watch video >>


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Astros rally for another win, 6-4 over Baltimore
Evan Gattis hit a three-run homer and Luis Valbuena added a go-ahead solo shot in a five-run third inning to help the Houston Astros to a 6-4 win over the Baltimore Orioles on Tuesday night.
The Astros, who lead the American League with a 33-20 record, were in a big hole early after a four-run second inning by the Orioles, but bounced back an inning later for their major league-leading 17th comeback victory this year.
Houston trailed by 3 when the homer by Gattis made it 4-all and the Astros went back to back when Valbuena homered to right field to put Houston on top. The Astros added an insurance run in the eighth inning.
Houston starter Collin McHugh (6-2) settled down after giving up four runs in the second, and the last out of that inning was the first of eight straight and 15 of 16 he retired before being replaced by Pat Neshek for the eighth inning.
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text:
- 1the act of putting your possessions, clothes, etc. into bags or boxes in order to take or send them somewhere Have you finished your packing? She finished her packing and zipped up the bag. When shall we do the packing?
- 2material used for wrapping around delicate objects in order to protect them, especially before sending them somewhere (British English) The price includes postage and packing.
BrE BrE//ˈpækɪŋ//; NAmE NAmE//ˈpækɪŋ//[uncountable]
Check pronunciation: packing


text:
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text:
Ice Yeti
Level: 32
Difficulty: 3 stars
Total HP: 1,918
- Slash: 36-47
- Headbutt: 36-47
Temporary Items Dropped:
- Battleground C Opponent Defeated (Dropped during the 'Levels 31-45' quest)
- Datharn Shard (Used to merge Datharn Key)
Items Dropped:
- Previously Legend Only.
- Also see:
Thanks to Poisonaplez.
Battle this monster in our free web game at www.AQ.com!


text:
With the deal gutted, the heads of state session concluded with a final battle as the Chinese delegate insisted on removing the 1.5C target so beloved of the small island states and low-lying nations who have most to lose from rising seas. President Nasheed of the Maldives, supported by Brown, fought valiantly to save this crucial number. "How can you ask my country to go extinct?" demanded Nasheed. The Chinese delegate feigned great offence – and the number stayed, but surrounded by language which makes it all but meaningless. The deed was done.
via How do I know China wrecked the Copenhagen deal? I was in the room | Mark Lynas | Environment | The Guardian.
Taking a vacation and using the Mayon Volcanic activities as excuse initially infuriated be when I read the reports. I am less mad now. I believe the President didn't know if she was going to be China or USA's lackey, might as well not get in the oven and get burned in the process. Shrewd move.


text:
Dear Sir/MadamMature
That's right.
You, with the eyes.
The one with the nose- right there! Above your mouth, Yeah -
that's the one.
it's closed, right?
Yeah - I thought so.
You feeling okay?
You look awful tired.
Getting enough sleep?
or is your brain too loud?
Do they let you dream, friend?
do they let you dream of towers and spirals and rolling fields of yellow,
oats soaked in vanilla and bathing in buttermilk?
Do they let you breathe?
Do your lungs work, friend?
You're living.
perhaps not, but living.
Are they kind to you, dear?
Showered with compliments?
Notice your new shoes? Haircut? New freckle on your back?
Are they fair? Are they kind?
or are you hiding?
silence with clear liquid, (no, it's not water!) and those tiny sweets you got from the doctor.
They are sweets, right?
Are you running, friend?
Are you slacking? Are you panting, worn out, so so
Like I said,
you look awful tired, tonight.
Run as fast as you like,
they're coming.
They come from the slobbering darkness,
have you got your torch, friend?
they can see in the dark.


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Let us know when your receive great advice so we can thank our lawyers and point others with similar questions in the right direction.Got it!
My husband just died. He didn't have a will. I can't find his passport or any of his important documents; I suspect that he may have had a safe deposit box but never told me. If I don't know the location of the box or if one even existed, how do I find that information out? Is there a way?
Sorry to hear about your husband's death. Most banks, credit unions etc. will not rent a safety deposit box to a person unless that person has an account there. From the mail you can probably figure out where he had accounts. With his death certicate in hand you can go to banks where he had an account and ask if he had a safety deposit box. If he does you will need a court order to get in. However, you may be able to find out if one exists.Ask a similar question
My colleague's response is in all respects correct. I just wanted to make one additional point. Many persons have a safe deposit box in a bank in which they previously had accounts, but long since closed or moved those accounts. If you cannot find a safe deposit box among the banks in which your husband had accounts, try looking through his canceled checks for the past year or so. Banks charge an annual fee for a safe deposit box.
Good luck to you.Ask a similar question
I am sorry you are going through this. What you will learn is that someone who dies without a Will creates extra problems and hassles for loved ones, and anyone who reads this answer should take to heart the advice that everyone, rich or poor, should have a proper Will and should make sure someone else in the family knows where things are.
You are going to need an attorney to help you with this. Most of us do not charge for an initial consultation to figure out what you need. An estate with no Will is known as an "intestate" estate. If you want to find out anything about your husband's assets (banks and investment firms will not give you information simply because you are his wife), you will need to go to the Probate Court and apply to be appointed as the "Administrator" of the estate. Most firms like ours who do lots of estate administration have lists of every bank in Central Ohio and are accustomed to contacting them to determine if the decedent has any accounts or safe deposit boxes.
If your husband had a safe deposit box, it is probably at a bank where he had an account. One way you can find out whether or not he had a safe deposit box is by looking at the checkbook register and all statements over the past year to see if he was paying the box rental, either by check or by direct transfer from a bank account. Annual rental statements might well have come in December or January. If you go to the bank regularly and have a relationship with a teller or branch manager, he or she might be sympathetic enough at your situation to look it up for you (although they are not supposed to do that and could get fired for releasing information without authorization).
There may be other aggravations such as transferring a car that was in his name, or collecting insurance policies or gaining access to funds in an account that was not joint. You need to gather up all information you have about real estate, cars, accounts, investments, pensions and other things and visit with a certified specialist in Estate Planning, Wills and Probate law.Ask a similar question
Post a free question on our public forum.Ask a Question
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Search for lawyers by reviews and ratings.Find a Lawyer


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Mixing Trap Songs & Creating Trap Effects
After recent work with Drake, Kendrick Lamar, Kanye West, Rick Ross, Future, Lil Wayne, and many others, Ken Lewis presents this deep two hour tutorial on mixing trap and creating common trap effects. Ken takes you through a complete mix, faders… right down to a finished full trap song… beat and vocals. Using both stock and 3rd party plugins, Ken breaks down step by step how to create many of the most common trap effects such as…
APR 05 2015 | 1.41GB [Read more…]
1554 Views


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… need to look at ways of solving this problem. Here are some tips and tools to get you started. 1. Sanebox This is one of my personal favorites. It basically manages your email by applying some automation processes to your inbox. It currently works with Gmail, Microsoft Exchange, IBM Notes and Office 365. When emails come to your inbox Sanebox…


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Affordable Dentures & Implants in Woodbridge, VA
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Guadalupe is living the American dream: "No one believed me, they all said I was crazy."
This the second of our stories in our series spotlighting U.S. businesses in celebration of Independence Day.
"After years of working for someone else, I decided it was time to pursue my dream of bringing the food of my childhood to my new home."
You can tell Guadalupe is a passionate woman from the moment you place your order at El Pipila. She is constantly moving around assembling the plates, but keeping an eye on everything that's going on, making sure everyone receives the best service.
Her passion comes in part from her journey to the United States, and as she discusses it Guadalupe's eyes fill with tears. Her daughter, Brenda, does most of the talking, to help her mother through it. Sixteen years ago Guadalupe decided to leave Guanajuato, a state in central Mexico, and join her relatives in the U.S.
Read Guadalupe's full story on Kiva's Medium page -->>


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Search chrisv10's books
Random books from chrisv10's library
Devil to Pay by Jeaniene Frost
Dark lover : a novel of the Black Dagger Brotherhood by J. R. Ward
Once Burned (Night Prince, Book 1) by Jeaniene Frost
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Lover eternal : a novel of the Black Dagger Brotherhood by J. R. Ward
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Quezal Art Glass and Decorating Co. (New York, 1902-24)
This antique, Art Nouveau lamp shade is handblown in a large lily flower shape. It is decorated with iridescent gold with green and purple highlights and a rich gold interior. Marked: Quezal. c. 1910 W 4.25 D 4.25 H 6.75 in. Fitter: W 1.25 in.
Centuries of Design, Antiques from around the World


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Mizzou Optical
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Communicate with your medical team, request medication refills and manage appointments through MUHealthe. Learn More
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Our support team is available 24 hours a day, seven days a week at 877-621-8014.
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TBX20 encodes a T-box family member. Additionally we are shipping TBX20 Proteins (9) and many more products for this protein.
Showing 10 out of 28 products:
Chicken Polyclonal TBX20 Primary Antibody for IHC, WB - ABIN2777791
Scherer, Cheung, MacDonald, Osborne, Nakabayashi, Herbrick, Carson, Parker-Katiraee, Skaug, Khaja, Zhang, Hudek, Li, Haddad, Duggan, Fernandez, Kanematsu, Gentles, Christopoulos, Choufani, Kwasnicka et al.: Human chromosome 7: DNA sequence and biology. ... in Science (New York, N.Y.) 2003
Chicken Polyclonal TBX20 Primary Antibody for WB - ABIN2778618
Kirk, Sunde, Costa, Rankin, Wolstein, Castro, Butler, Hyun, Guo, Otway, Mackay, Waddell, Cole, Hayward, Keogh, Macdonald, Griffiths, Fatkin, Sholler, Zorn, Feneley, Winlaw, Harvey: Mutations in cardiac T-box factor gene TBX20 are associated with diverse cardiac pathologies, including defects of septation and valvulogenesis and cardiomyopathy. in American journal of human genetics 2007
data demonstrate that elevated glucose alone induces cardiac defects in zebrafish embryos by altering the expression pattern of tbx5 (show TBX5 Antibodies), tbx20, and has2 (show HAS2 Antibodies) in the heart
embryos lacking hrT function have dysmorphic hearts and an absence of blood circulation
redundant activities of Nkx2.5 (show NKX2-5 Antibodies) and Nkx2.7 are required for cardiac morphogenesis (show XIRP1 Antibodies), but Nkx2.7 plays a more critical function, regulating the expressions of tbx5 (show TBX5 Antibodies) and tbx20 through the maturation stage
we show that TBX5 (show TBX5 Antibodies) and TBX20 can physically interact and map the interaction domains, and we show a cellular interaction for the two proteins in cardiac development
The current study associated TBX20 haploinefficiency with isolated Dilated cardiomyopathy (DCM), and expanded upon the mutational spectrum of TBX20 associated with DCM and congenital heart disease (CHD (show CHDH Antibodies)), which provides novel insight into the molecular mechanism of DCM and CHD (show CHDH Antibodies), suggesting potential implications for early personalized treatment of these diseases.
Silencing of TBX20 in rat myocardial and human embryonic kidney cells significantly inhibited cell proliferation, induced cell apoptosis and led to G2/M cell cycle arrest.
rs3999950 may be associated with congenital heart disease, and TBX20 may predispose children to the defect.
Among the 8 SNPs identified, 6 are in strong linkage disequilibrium and the minor alleles are associated with lower CHD (show CHDH Antibodies) risk. The minor alleles have lower transcriptional activity than major alleles in both human heart tissues and three cell lines. TBX20 minor alleles may exhibit higher binding affinity with certain transcription repressors.
Cardiac TBX20 expression showed a negative correlation with LVEF and a positive correlation with left ventricular end-systolic volume. No significant difference in TBX20 CNVs and promoter methylation was observed between IDCM patients and control group
The mutation markedly reduced the synergistic activation of TBX20 with NKX2-5 (show NKX2-5 Antibodies) or GATA4 (show GATA4 Antibodies).
We report three missense mutations (Y309D, T370O, and M395R) within the transcriptional activator domain of human TBX20 that were associated with atrial septal defect
Data showed that the TC genotype of SNP rs3999941 and AC genotype of the new SNP c.657A>C in the TBX20 gene may be risk factors for CHD (show CHDH Antibodies).
TBX20 loss-of-function mutation contributes to double outlet right ventricle
A novel TBX20 mutation, c.526G>A (p.D176N), was identified and co-segregated in all affected members in this family of three generations with atrial septal defects.
Cardiomyocyte Tbx20 induced overexpression activates multiple cardiac proliferative pathways, directly represses cell-cycle inhibitory genes p21 (show D4S234E Antibodies), Meis1 (show MEIS1 Antibodies), and Btg2 (show BTG2 Antibodies), promotes adult CM proliferation; and preserves cardiac performance after MI.
TLE1 (show TLE1 Antibodies)/TLE3-NuRD corepressor complex facilitates Tbx20-dependent transcriptional repression.
The effects of Tbx20 are epistatic to Tbx3 (show TBX3 Antibodies) in the heart, but Tbx3 (show TBX3 Antibodies) is epistatic to Tbx20 with respect to developmental delay.
Tbx20-mediated increases in cell proliferation, providing evidence for parallel regulatory pathways downstream of BMP/Smad1 (show SMAD1 Antibodies)/5/8 signaling in promoting cardiomyocyte proliferation after birth
Tbx20 is expressed in the developing endocardial cushions and valves throughout heart development. Ablation of Tbx20 in endocardial cells causes severe valve elongation defects and impaired cardiac function.
a dual role for TBX20 as both a transcriptional activator and a repressor, and that each of these functions regulates genes with very specialized and distinct molecular roles
Data show distinct functions for Tbx20 in regulation of cardiomyocyte lineage maturation and cell proliferation at embryonic and fetal stages of heart development.
Genome-wide ChIP analysis of Tbx20-binding regions in the adult heart revealed that many of these genes were direct downstream targets of Tbx20 and uncovered a previously undescribed DNA-binding site for Tbx20.
mice lacking Tbx20 in the atrioventricular canal myocardium fail to form the atrioventricular canal constriction, and the endocardial epithelial-mesenchymal transition (EMT (show ITK Antibodies)) is severely perturbed.
the BMP10 (show BMP10 Antibodies)-Tbx20 signaling cascade is important for ventricular wall development and maturation.
This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
T-box 20
, T-box transcription factor 20
, Tbx20-like homeobox protein
, H15-related T-box transcription factor hrT
, T-box protein 20
, T-box transcription factor TBX20
, cTbx20


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Reverse mixed up offset account?
Discussion in 'Accounting & Tax' started by LucyCat, 24th Apr, 2016.
Page 1 of 2
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Un gagnant a été sélectionné de 143 designs proposés par 33 designers freelance.
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After The Biggest Loser: How To Keep The Pounds Off
Even though Tumi Oguntala didn't win "The Biggest Loser" competition, she hasn't stop losing. In fact, since leaving the ranch behind, she hasn't had any problem shedding pounds. Tumi was the "At Home Winner" with the largest percentage of weight loss ever achieved in the show's history. She lost 175 lbs which is 54.86% of her body weight!
But what is it that contestants like Tumi learn to help take their weight loss to the next level even after the camera stops rolling?
On The Show:
"In May 2013, frustrated with inconsistent results from my weight loss program, I decided to try out for 'The Biggest Loser.' I was cast on the show after attending an open casting call in May 2013. The program is an intense immersion into living the life of an athlete (exercising four or more hours per day) and eating clean (organic, hormone-free, low sodium, low fat, low sugar and few to no processed foods).
The competitive aspects of weight loss require contestants to adapt to an athlete's life very rapidly or leave the ranch.


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Earth and Moon
Poem by: laolsen
Status: Finished
Genre: Poetry
I think of you every day,
when I look up in the sky,
when I swim down in the sea.
Our love is everlasting,
a bond between two.
Like the Earth and the moon,
a pulling attraction that continues to endure.
I can not mention the pain of not having you,
my bones ache and my teeth grind, my hands shake
and my heart stops.
Never more do i wish for this,
without you my moon, I would cease to exist,
my sea's would be violent, and deathly at most.
But if we stay together, just you and I, we can at most,
try and try. Though those may try and move us apart,
my love for you shall never part.
© Copyright 2017 laolsen. All rights reserved.
Add Your Comments:
This is a good poem. I really like it
Aw, this was very beautiful. Great poem =]
This is pretty good! Keep it up! ^^
I like this one. It makes me think about things in my life, which is something that I aim for when I write poetry, so good job!
Wow, that is giving courage to see that things will get better on the f***** up situation I have been in, thanks and our love is strong. Your writing is helping me. I'll see my love on tuesday then and finish sorting things out, cause it is killing me. besides nice poem.
If a guy ever wrote me a poem like that I would melt! Good job!
it's a lovely expression for love. good style. ;-)
Other Content by laolsen
Book / Mystery and Crime
Short Story / Romance
Poem / Poetry
Short Story / Mystery and Crime
Book / Thrillers
Short Story / Young Adult


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Studio 360
Follow the Stimulus Money
This spring the federal economic stimulus package started doling out $787 billion. And $3.8 million (that's 1/200,000th of it) went to Rochester, NY for the expansion of ARTWalk, the town's funky urban sculpture trail. But not everybody thinks that a public art project will do much to stimulate the economy. Produced by Dave Johns.
Music Playlist
MontrealArtist: Kaki KingAlbum: Dreaming of RevengeLabel: Velour Recordings


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