text:
"I never believe what you say, MUSLIM HATER. I only believe that you hate Muslims." ~ bmzHe failed to complete the mission for which he was sent but he succeeded in his own mission of destroying the peace. I think taht is the only thing that he accomplished. Don't you think so, Buford?
May the LORD have mercy on the biblical Jesus' soul. Aaaamen!
Who Is Allah?
There are 256361 comments on the The Brussels Journal story from Aug 24, 2007, titled Who Is Allah?. In it, The Brussels Journal reports that:
"Allah is a very beautiful word for God. Shouldn't we all say that from now on we will name God Allah? [...] What does God care what we call him?"
From the desk of Soeren Kern on Fri, 2007-08-24 11:56 Europeans love to mock the salience of religion in American society. via The Brussels Journal
Join the discussion below, or Read more at The Brussels Journal.
#154642 Nov 20, 2012
Since: Mar 08
Location hidden
#154643 Nov 20, 2012
Buford, do you love me?
Since: Mar 08
Location hidden
#154644 Nov 20, 2012
I have already condemned Hamas' Charter. It has to be re-written.
You cannot say that Ghazans do not want peace. Who doesn't want peace?
I have also told you about the mentality and the mindset of Israelis (excluding the natives) and their leaders, who are full of hate without a written charter and do not want to establish peace.
Queens Park, Australia
#154645 Nov 20, 2012
in bigining is word
word is been with your real Creator..
moli se=pray
mulise musli
read better
as well not judge
Kingston, Jamaica
#154646 Nov 20, 2012
Tell me what are human rights.
#154647 Nov 20, 2012
Hamas doesnt want peace. And every Gazan that supports them does not.
And if you believe that many of the Gazans dont support Hamas, then logically you should support the Israeli action as it is intended to liberate gaza from the clutches of Hamas.
Thats a generalization, that based on my experience is incorrect. And prejudicial. You are buying into a false narrative again.
If you have direct experience otherwise from living or visiting Israel - please feel free to use it to back up your statement. If not, then you need to retire that narrative too.
#154648 Nov 20, 2012
The ability for two men to walk down a street holding hands without the fear of being beat up. Or some doofus claiming that the laws of the state forbid this.
#154649 Nov 20, 2012
Why should it be written? They are just being honest. In fact they are being more honest than the Palestinian Authority which promotes the same but pretends otherwise.
And HOW COULD it be rewritten? The basis for the existence of Hamas is to throw the Jews into the sea. HOW CAN you rewrite that without loosing that message?
You shouldnt bother condemning Hamas charter because it brings scorn on your religion. The Islamic citations are not the problem. The vision is the problem. You should be condemning the vision, and therefore the organization. I only brought up the charter because it illuminated how the organization thinks. It is not the cause of the THINKING of the organization.
Why cant you understand what terrorism is?
Kingston, Jamaica
#154650 Nov 20, 2012
1.Your concept/question should be asked of ALL groups e.g. do Hindus like Christians and so on.
2.Your wife loves you
3.I love you
4.Above ALL, God loves you
Kingston, Jamaica
#154651 Nov 20, 2012
HughBe---Tell me what are human rights
Frijoles--The ability for two men to walk down a street holding hands without the fear of being beat up.
HughBe--- My question was WHAT ARE and I take it that your answer above is the sum total of your concept of human RIGHTS.
Frijoles--Or some doofus claiming that the laws of the state forbid this
HughBe--- The laws either FORBID the act or it does NOT. There is no need for YOU to call anyone DOOFUS etc. because they articulate the law.
Why do YOU condone BREAKING the LAW?
Kingston, Jamaica
#154652 Nov 20, 2012
#154653 Nov 20, 2012
So there is a law in Jamaica that forbids two men from walking down the street holding hands?
How sad.
No wonder Jamaica is considered as a place that doesnt respect human rights.
Since: Mar 08
Location hidden
#154654 Nov 20, 2012
Frijoles, you do not know the monstrous nature and the evil mind of Israel's leaders. They are as evil as the Palestinian and Arab leadership.
I have been blunt and straight as far as my replies are concerned.
That the Charter of Hamas, should be re-written is my view because it mixes Islam into the dirty and filthy politics played by Israeli and Palestinian leadership. It was a suggestion.
It does not bring any scorn to my religion. In fact, it brings scorn to Judaism and her people, who read and recite some of the ugly and horrendous chapters of the Bible every day. You and I know well how the minds can be poisoned easily with the daily dozes.
Their vision is for freedom and land, which Israel has usurped. How can I condemn that vision? If Israel can be cut down back to size before 1967 war, I think there can be peace.
I condemn both the Palestinians and the Israelis for being dimwits, who cannot talk to each other and make peace. 2-3 generations have been the product of this conflict, where both are full of hate and raised/brought up in hate for each other. Didn't you watch the video clip on the Israeli General's son?
I also condemn those untrustworthy, unreliable and hypocritical outsiders, who claim to be peace-makers but are, in fact, working to make sure that there is no real peace established.
When Russia hammered Georgia, the US and the EU machinery ran full speed to make peace. How come the same bunch has been unable to do that over 45 plus years?
How can makers of war and war-mongers bring peace to others?
Yesterday, I compared Ghaza with Auschwitz Camp. Have the Israeli leaders forgotten how their own people felt, when they were kept in that camp?
I am sure you know well that the Jews ran to Islamic states to save their lives, when they were being annihilated by European Christians. We are their saviors. If there were no Islam, the Jews would have become extinct at the hands of European Christians.
There is a great diference between the Jews of the West and the Jews of Israel. You cannot say that the Israeli Jews are just as good and well-educated as the Jews living in the West. The Israeli mindset and upbringing is exactly the same as that of the Palestinians. Israeli Charter is kept confidential and Oral.
Hope this helped.
This is a political problem and has nothing to do with religion. How can you trust the Christian or the Western world to fix up this problem?
Since: Mar 08
Location hidden
#154655 Nov 20, 2012
I love you, HughBe.
#154656 Nov 20, 2012
Can someone please explain how on one hand Muslims consider Jerusalem a holy city, and on the other hand FIRE ROCKETS at it?
At THEIR OWN people?
2 rockets fired at Jerusalem
Siren sounds in capital as UN chief visits city. One rocket lands in Gush Etzion.
For the second time since the beginning of Operation Pillar of Defense, an air raid siren sounded in Jerusalem at around 2:15 pm, shortly after the arrival of UN chief Ban Ki-moon to the city.
The rocket likely landed in Gush Etzion. Hamas claimed responsibility for the firing. No injuries or damage were reported.
Israeli and Palestinian residents told Ynet that the rocket landed in an open area between two Palestinian villages.
#154657 Nov 20, 2012
You make a multitude of false comparisons
1. Gaza as Aushwitz (Are their death camps there? is their a food blockade?)
2. Israeli leaders as murderous (Do Israelis fire rockets indescriminately at a civilian population?)
3. The application of Judaism vs the application of militant Islam (Again where are the hordes of jews revering martydom?)
4. Annexation of west bank vs gaza.(Didnt Israel FULLY remove itself from Gaza in 2005? When did the military blockade start - was it then, or AFTER the first wave of violence?)
Finally - the last (and first question)- HOW do you negotiate peace with an organization that exists to wipe you out?
Dont put the blame for Israel on that one.
#154658 Nov 20, 2012
Unfortunately in Hughbes country , it is UNLAWFUL for you to express that love.
#154663 Nov 20, 2012
rabbee: so you agree with the devil, that sinning is your being a talking critters right?
because male effimacy, according to TheTorah. is not, a human right. you need to consider, just who's side you are really on - G-D'S or the subtle smooth talking critters.
#154664 Nov 20, 2012
rabbee: oh yeah! lets just blame the less guilty, more responsible. and not even hold the more guilty, responsible for greater evil and wickedness. and make your silly and stupid rules, that the less guilty. can't even carry, a knife to a gunfight.
no i do not think, the arabs and muslems. would all think, it is fair. if you took away, their ak-47's and rocket launchers. tied their hands behind their back, and told them they could only fight with their teeth.
#154665 Nov 20, 2012
rabbee: so? that does not explain, why this whole insane world. is constantly making all the same, continious mistakes over and over again. and then expect that G-D, won't almost completely destroy the whole world. exactly the same, old way again. because you all only think, that G-D is the only liar.
as all the false, not here in TheTorah prophets. are accusing TheG-D of always the same way, for your errant mentality. is going to do, it differently. when i can assure you all, that TheG-D of Only TheTorah here in IT. is not about to do anything different, as long as all you talking critters are against HIM.
but as long as everyone on earth, is guilty of not being here in TheStory of Creation. because they are all, worshiping other g-ds. i do not see, anything happening any different. than all the other, Torot bygone times. and i do not see G-D ever, giving talking critters and their followers any human rights in TheTorah.
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Welcome Back
I dropped the bags onto a white rug in the middle of the room and began to unpack my clothes into the antique wardrobe. To brighten it up, it had been painted with mythical creatures. I recognised my mother's handiwork in the flowers that entwined them all. To my surprise, there were already some clothes in there that had obviously been bought for me, including a black school uniform. I shut the doors on it and turned my attention to unpacking my books and DVDs onto the shelves above a large beech desk. They already held some childhood trinkets, snow globes and ornaments and a teddy bear called Mr Moon and a rag doll without a name. I had brought my laptop as well, carefully cushioned in my bag with some clothes. I plugged it in to the socket below the desk and fed the wire up behind it, setting the laptop up on top of it. Once I was satisfied with my new room arrangements, I opened the curtains and looked out of the window. It was at the side of the house but I could see half of the garden. There was a stone path and a little pond between some flower bushes. The poles of a child's swing stood rusting in the corner and a wooden bench faced the pond. I didn't remember the pond, but the swing must have been mine.
I shoved the empty bags under my bed and went back down the stairs slowly, trailing my fingers along the banisters. The house was cosier than the flat and I wanted to belong here, despite my misgivings about it. Since I was going to be staying for at least half a year, I hoped I would fit in.
When I got to the kitchen the smell of warm pizza and paint reached me. Drying paintings hung all over the primrose yellow walls, and two steaming pizza boxes stood on the pine table. It was square with three chairs, one side pushed against the wall. My mother was washing some dishes, and looked round guiltily as I walked in.
"Sorry, but I ordered delivery pizza. I didn't think I should cook."
I shrugged and opened a box, pulling out a slice and almost dropping it as it burned my hand. Deftly a plate appeared and caught the slice just as I dropped it. I raised my eyebrows at my mother's sudden bout of dexterity and took the food into the living room, sitting in front of the TV. After a while she joined me and we ate in companionable silence in front of an American sitcom. It was an odd feeling that although I hadn't been here, with her, for ten years, after an hour I already felt at home. I wasn't even that worried about staying here anymore. Though when I thought of school, something cold twisted in my stomach. That I was definitely not looking forward to, and that fact wasn't likely to change. As it was a Sunday, I was going to start at the secondary school in Slake the next day. It felt like being thrown into the deep end before you've learnt how to swim.
On Monday morning I was awake at five, feeling too sick with nerves to sleep. An hour later, I made the bed and reluctantly dressed in the school uniform. It consisted of black trousers, a white shirt and a blue striped tie. The blazer had a logo on the pocket, the outline of a city horizon emblazoned with the words 'Slake Community High School' in white. It was unfamiliar. It felt like I was wearing a stranger's clothes.
My mother drove me to school at half past eight, cursing the traffic in every lane. The new car was too big to overtake others in the narrow lanes, so we sat restlessly as the clock on the dashboard kept ticking the minutes away. It was so typical for me to be late on my first day. Just what I needed - a dramatic fashionably late entrance with everybody staring at me.

subset: commoncrawl


text:
East Carolina, one of the most dangerous mid-sized programs of the 1990s, is creeping back to glory with Skip Holtz at the steering wheel. In just his third season at the school, he's way ahead of schedule, bringing a new attitude and toughness to a program that had lost its way under former coach John Thompson. Although they were soundly beaten by South Florida, appearing in the Papajohns.com Bowl afforded the Pirates a rare appearance on national television, along with 15 extra practices to prepare underclassmen for this year. With rumors swirling that he'd be lured to a bigger school, Holtz coming back for another year was the biggest news of the off-season.
Head coach: Skip Holts
3rd year: 12-13
Returning Lettermen:
Off. 25, Def. 25, ST 4
Lettermen Lost: 20
Best ECU Players
1. OT Josh Coffman, Sr.
2. DE Marcus Hands, Jr.
3. LB Quentin Cotton, Jr.
4. RB/KR Chris Johnson, Sr.
5. FS Van Eskridge, Soph.
6. WR Phillip Henry, Sr.
7. NT Mark Robinson, Sr.
8. LB Fred Wilson, Sr.
9. DE C.J. Wilson, Soph.
10. OG Matt Burlter, Sr.
the Pirates are to build on 2006, they'll do so on the backs of both
lines, which return every starter plus just about every reserve. Holtz
has been working to build depth and competition in the trenches, a
luxury he'll enjoy in 2007. All eyes this summer will be on the
competition to replace the James Pinkney to Aundrae Allison hook-up, the
offensive catalyst the last two years. The quarterback battle between
last year's backup, Rob Kass, Brett Clay and Patrick Pinkney will be
vital to determining ECU's immediate future.
After winning games against Virginia, Southern Miss and N.C. State last year, East Carolina is confident and ready to take the next step: winning a conference championship. If the offense doesn't drain the defense with endless three-and-outs, the Pirates are in a position to be the class of a weak and winnable Eastern Division.
What to watch for on offense: Holtz likes an up-tempo offense that spreads the field, but he's also flexible enough to tailor his attack to the personnel on his roster. In other words, the offensive line, led by senior right tackle Josh Coffman, better be prepared to open more holes for the backs than it did last fall. Kass was sharp when pressed into action in the bowl game, giving him an edge in the battle to replace Pinkney behind center.
What to watch for on defense: With every relevant player from the front seven back, East Carolina has to be better at pressuring the quarterback than last year. If it's not, it could be a long season for a revamped secondary that'll be breaking in three new starters. The defense may be short on stars, but it's experienced, closes quickly to the ball and can create turnovers.
The team will be far better if …the young offensive line grows up. The Pirates were forced to start three freshmen last year, which hurt at the time, but should pay dividends in 2007. With few playmakers and without an experienced quarterback, it's imperative that the line delivers if the offense is going to have any chance of producing points.
The Schedule: It starts out a bit rough with non-conference games against Virginia Tech and a refurbished North Carolina, but the big deal is the Conference USA opener against defending East champion Southern Miss. With road trips to West Virginia and Houston to end the first month, ECU just has to survive. The final seven games of the year are against teams that didn't go to a bowl game. Winning all the league home games is a must to have a realistic shot at a bowl.
Best Offensive Player:
Senior RB Chris Johnson. Will he actually be a running back again? After
being one of the league's best all-around backs for two years, becoming
a great receiver while serving as a decent runner, last year he only
rushed for 314 yards and four touchdowns while turning into a special
kickoff returner. He'll likely combine with Dominique Lindsay to carry
the workload.
Best Defensive Player: Junior LB Quentin Cotton. Only 224 pounds but fast, he finished second on the team with 68 tackles and was decent at getting into the backfield. After he comes back from a shoulder injury, he'll be the leader of a veteran linebacking corps that should be one of the team's biggest strengths.
Key player to a successful season: Sophomore QB Rob Kass. He'll have to hold off Patrick Pinkney and Brett Clay for the gig, but the 6-4, 250-pound sophomore was the top backup last season and should become the type of passer to build the offense around for the next few years. He's not going to run much, but he'll bomb away.
The season will be a success if ... the Pirates win the East. The schedule works out relatively well, getting Southern Miss at home and missing Houston, Tulsa and SMU from the West. A few key players must become stars in a hurry to get the offense rolling, but it might take a while. Basically, the team has to get through the first month without thinking the season is lost, and then hit its stride late.
Key game: Sept. 15 against Southern Miss. If ECU wants to go where it hopes to be, it has to beat the best. Southern Miss is the star of the East, and if the Pirates can come through with a win in the conference opener, it'll be the lead dog in the division pack. A loss could possibly mean an 0-5 start.2006 Fun Stats:
- Third quarter scoring: Opponents 39; East Carolina 29
- Red zone touchdowns: Opponents 28 of 43 (65%); East Carolina 21 of 44 (48%)
- Sacks: Opponents 29 for 209 yards; East Carolina 18 for 100 yards


text:
Kim Kardashian, Kanye West to marry?
London: Reality TV star Kim Kardashian and Kanye West will reportedly get married as soon as she finalises her divorce from Kris Humphries.
The pair recently announced they`re expecting their first child together, and are keen for the baby to be born out of wedlock, reported Showbizspy.
"Kim has been trying for a baby for a few months. She got off birth control and it was a decision she and Kanye both made. They wanted to get married before starting a family but the divorce changed everything because its taken so long to finalize. Kanye and Kim will definitely get married after the divorce is settled with Kris," a source said.
Kardashian last year called of her 72-day marriage to basketball player Kris Humphries.


text:
Weigel's 2539
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I got to sit in on a lengthy demo session with LocoRoco 2 back at Tokyo Game Show, and Sony is certainly cramming it top to bottom with what looks like a large amount of new content. My biggest complaint about the first LocoRoco was that the basic world-tilting, blob-hopping gameplay mechanics weren't enough to hold my attention for the duration of an entire game. This time around, however, there's a ton of features and content you didn't see in the original. Here's a list of things I wrote down in my notebook during that TGS demo.
- "4p minigame battles!"
- "FMVs look like claymation"
- "New quests open up when you finish levels with certain conditions"
- "New mechanics -- bite long grass to swing on it, bite some objects to pull them out of the ground"
- "Musical minigames"
- "Mui house looks more interesting. Make different rooms out of collected parts, attract more Muis to house"
- "New LocoRoco character is purple, has a mohawk, likes punk rock, 'looks like a German girl'" (developer's words, not mine)
- "Dolphins, apes, owls, oh noes!"
(Apparently I was feverish at TGS, I don't know.)
Then again, the core mechanics--with you tilting the world with the L and R buttons to make your blog roll around--also appear to be unchanged. Is all this enough to make you want to re-up for more LocoRoco action next month? For $20, at least the barrier to entry is unimposing.


text:
RECIPE SECTION - Over 10,000 Recipes
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Jay, Susan's husband, has donated this sauce from his collection, and we just love it over pasta or polenta. It's a sauce that's packed with flavor, as well as antioxidants, and goes with just about anything.
Yield: 6 servings
Jay's Tomato Fennel Red Sauce
• 1 medium onion, finely chopped
• 3 cloves garlic, minced
• 1 teaspoon cracked black pepper
• 1/4 cup chopped fresh basil
• 2 tablespoons chopped fresh oregano
• 2 tablespoons chopped fresh rosemary
• 1 tablespoon fennel seeds
• 14.5-ounce can diced tomatoes, no salt added
• 15-ounce can tomato sauce, no salt added
• 6 sun-dried tomatoes, quartered, preferably Sonoma brand
Saute the onion and garlic in 2 tablespoons of water over medium heat until translucent, about 5 minutes.
Add the spices, herbs, fennel seeds, and stir well to infuse flavor.
Add the tomatoes and tomato sauce, reduce the heat, and simmer for 30 minutes.
Add the sun-dried tomatoes and simmer for an additional 15 to 30 minutes.
Serve with polenta or your favorite pasta!
Each serving contains approximately: Calories 63, Fat calories 4, Fat 0.5g, Saturated fat 0.1g, Cholesterol 0mg, Protein 2g, Carbohydrate 12g, Dietary fiber 3g, Sodium 37mg, Omega-3 fatty acids 0g
Allowances: 2 1/2 vegetables
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text:
|Publication number
|Publication type
|Application number
|Publication date
|May 15, 1990
|Filing date
|May 5, 1988
|Priority date
|Nov 13, 1981
|Fee status
|Publication number
|Theodore E. Spielberg
|Original Assignee
|Spielberg Theodore E
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (4), Non-Patent Citations (2), Referenced by (10), Classifications (16), Legal Events (5)
|External Links: USPTO, USPTO Assignment, Espacenet
This is a continuation of application Ser. No. 759,970, filed on Jul. 29, 1985, which is a continuation of Ser. No. 507,997, filed Jun. 27, 1983, which is a continuation of Ser. No. 321,099, filed Nov. 13, 1981, all now abandoned.
A. Field of the Invention
The invention relates to artificial organs and glands and comprises an ultra filtering hybrid artificial organ or gland for providing a corrected physiological response to blood constituents in a rapid manner.
B. Prior Art
Increased activity in recent years has been devoted to developing artificial organs of various kinds. Much of the early effort has been devoted to developing organs which perform primarily mechanical functions, e.g., the heart. More recent activity has extended to the construction of organs which attempt to duplicate body physiology, e.g., dialysis devices and the like. This typically presents a more difficult problem than duplication of mechanical functions, due to the compexities of the physiologic system. An even greater level of difficulty is presented in the design and construction of devices which duplicate glandular functions, and progress in this area has been less rapid than in others.
Several devices which perform the function of the endocrine pancreas have been proposed. Aside from wholly artificial devices that depend on glucose sensors, algorithmic contollers, and refillable insulin reservoirs, attempts have been made to utilize natural pancreatic beta cells within an artificial structure as a form of protected and facilitated transplantation known as a hybrid artificial pancreas. Such devices include mechanisms for closely contacting the blood of a patient with this living glandular material, usually through a microporous membrane separating the two, so that the glandular material may respond to various constituents in the blood and exchange selected material therewith by simple diffusion, yet avoid rejection by host lymphocytes and antibodies that are too large to pass through the pores. In these devices, the glandular material actually adheres to the membranes and grows into and encroaches the pores resulting in proximity to the blood compartment improving diffusion back and forth across the membrane.
Such devices constitute an advance in the art but suffer the critical disadvantage, among others, that there is a significant time delay in the process of diffusion of various constituents, such as glucose and insulin, across the membrane despite the use of large membrane surface areas. This delay is undesirable to the extent that it departs from the normal tight physiological control and, in some cases, may present a risk to an individual dependent on such a device for rapid response to abnormal body conditions, i.e., a stressed diabetic relying on the device for production of insulin in response to acutely changing glucose levels in the blood. Additionally, this loose control of blood sugar may prevent the long-term tight control of diabetes necessary to prevent the complications of retinopathy and nephropathy, neuropathy, and accelerated vascular disease that all too often results in blindness, kidney failure, impotence, and premature heart attack.
Accordingly, it is an object of the invention to provide an improved hybrid artificial organ or gland.
Further, it is an object of the invention to provide an improved hybrid artificial gland.
Specifically, it is an object of the invention to provide a hybrid artificial pancreas, liver, or kidney, providing an improved response to body stimuli.
For purposes of illustration, the present invention will be described primarily in terms of an artificial gland and, more specifically, a hybrid artificial pancreas. However, it should be understood that the device of the present invention is also particularly well adapted to function as an artificial non-glandular organ as well (e.g., liver and kidney), with certain modifications that will be described later, as well as an endocrine gland in general. In accordance with the preferred embodiment of the present invention, I provide an ultra filtering hybrid artificial pancreas formed from two treatment stations in series, the first of which forms an ultrafiltrate through a microporous membrane from preferably arterial blood supplied to it, and the second of which contains a cellular exchange medium, such as beta cells, which respond to both the ultrafiltrate and to the whole blood for necessary oxygenation, to provide the desired physiologic response to constituents in the ultrafiltrate and in the blood. The ultrafiltrate and the blood, now carrying the response constituent(s) of the cellular exchange medium (insulin), are then recombined, either by direct mixing or by reabsorption of the ultrafiltrate into the bloodstream via a microporous membrane, and the blood returned to the body system.
Ultrafiltration (as contrasted with simple diffusion) relies on a hydrostatic pressure gradient across a membrane (instead of a concentration gradient); this results in large numbers of molecules "streaming" unidirectionally through pores in unison (rather than moving bidirectionally as in simple diffusion). This phenomenon of ultrafiltration is referred to technically as "convective mass transfer" or "solute drag", since adjacent molecules drag each other across the membrane; in consequence, molecules such as glucose for example, are washed across the ultrafiltration membrane much more rapidly than would be the case with simple diffusion. Consequently the surface area of the ultrafiltering membranes may be significantly reduced as compared to diffusion membranes in previous devices, thereby allowing more favorable design alternatives.
The resulting component of ultrafiltrate is generally quite similar to that of the fluid compartment of whole blood from which it is derived except for a depressed calcium level, and the absence of proteins and cells. Specifically, the concentration of glucose in the ultrafiltrate closely tracks the level of glucose in the blood from which it is derived at any given time. Thus, the response of beta cells to the ultrafiltrate is very close to the normal physiological response of these cells in a nondiabetic individual. Moreover, the glucose-insulin exchange across a semipermeable membrane with beta cells on one side and ultrafiltrate on the other is significantly faster than that across a corresponding membrane having beta cells on one side and whole blood on the other side, where proteins and blood cells interfere with transfer through the membrane pores. Thus, the device of the present invention provides a significantly faster physiological response than one in which the exchange takes place by simple diffusion with whole blood only. However, it also provides immunologically protected contact, through a microporous semipermeable membrane, between the beta cells and whole blood which contains oxygenated red blood cells in order to maintain the continued viability of the beta cells.
In the preferred embodiment of the invention, the exchange station comprises a chamber having first and second tubular membrane coils formed therein for transporting ultrafiltrate and blood, respectively, through the device. The chamber is filled with glandular or organ materials such as beta cells which, in response to glucose or other constituents in the ultrafiltrate and/or in the blood, release insulin which crosses the respective membranes to the ultrafiltrate and to the blood. The ultrafiltrate and the blood are then recombined, after their exposure to the beta cells, for subsequent utilization by the body. In this embodiment, the membrane separating the ultrafiltrate from the exchange cells may advantageously have a significantly larger pore size than that separating the blood stream from the cells, since the ultrafiltrate is free of adverse immunological agents such as cells and antibodies which might otherwise attack the exchange cells. A larger pore size provides more rapid transfer of insulin to the ultrafiltrate and thus, ultimately, to the patient's bloodstream.
In another embodiment of the invention, the ultrafiltrate is supplied directly to the exchange chamber where it comes in direct contact with the beta cells for ultrarapid stimulation of insulin production. The ultrafiltrate is then re-absorbed through the pores of the membrane separating the bloodstream from the exchange medium and it is then returned to the body together with the blood. In cases where the reabsorption rate of this system would be inadequate, due to the particular flow rates or membranes used, or due to other such factors, provision may be made for directly draining a portion of the insulin-containing ultrafiltrate from the cellular exchange portion by a mechanical bypass which reunites it with the bloodstream. This alternative results in yet another unique feature of the device, that of transporting insulin directly to the bloodstream, instead of relying on the much slower diffusion of insulin across microporous membranes as in previous devices. This results in a shorter, more nearly "correct" physiological response time, and compensates for the slower diffusion rate of insulin compared to glucose, since the diffusion rate is a function of molecular weight rather than solute size as in ultrafiltration. A microporous membrane of much greater pore size than that of the membrane carrying the blood through the exchange channel may be interposed in the drain to prevent loss of cells from the exchange chamber while allowing rapid passage of insulin with the ultrafiltrate. Due to the tendency of beta cells to aggregate and clump on membrane walls, and thus anchor themselves to it, it is possible that even the drain membrane may be dispensed with, with only slight loss of beta cells.
The ratio of ultrafiltrate flow to blood flow directly affects the response characteristics of the device. The greater the ultrafiltrate flow in relation to the blood flow, the more rapidly the device responds to physiologic changes in the bloodstream. However, when the device is used as a hybrid organ, where a portion of the ultrafiltrate may result in an excretory product (e.g., bile or urine), too great a ratio of ultrafiltrate flow to blood flow could result in adverse physiological effects (e.g. dehydration). This ratio may be controlled by varying the hydrostatic pressure in the ultrafiltration portion, as well as by appropriate selection of the ultrafiltration membrane area and configuration, the diffusion membrane area and configuration, membrane thickness, pore size, transfer coefficients, and support design, especially the size and configuration of the transport tubes for the blood and the ultrafiltrate. Additionally, this ratio can be controlled by bypassing portions of the blood flow around the ultrafiltration station or around the cellular exchange portion, or by bypassing portions of the ultrafiltrate flow around the cellular exchange station. Various embodiments effectuating these flow patterns are described herein.
When used as a hybrid artificial organ, a channel may be formed to drain a portion of the treated ultrafiltrate away from the bloodstream, to thereby remove, for example, waste products such as urine or bile when the device is utilized as an artificial kidney or liver.
The foregoing and other and further objects, features, and advantages of the present invention will be understood more readily on reference to the following detailed description of the invention, when take in conjunction with the accompanying drawings in which:
FIG. 1 is a view in perspective, with portions cut away, of a preferred embodiment of the invention showing the serially-connected ultrafiltration and cellular chambers;
FIG. 2 is a diagrammatic view of an alternative form of the invention in which the ultrafitrate is brought into direct contact with the beta cells;
FIG. 2A is a diagrammatic view of an alternative form of the invention illustrated in FIG. 2 showing the provision of an auxiliary shunt for expedited recombination of the treated ultrafiltrate and the whole blood component;
FIGS. 3A, 3B, and 3C are diagrammatic illustrations of still further alternative embodiments of the invention showing additional techniques for controlling the ratio of ultrafiltrate flow to whole blood flow; and
FIG. 4 is a diagrammatic illustration of an artificial organ in accordance with my invention.
In FIG. 1, an artificial gland 10 in accordance with the invention is formed from an ultrafiltration chamber 12 serially connected to a cellular exchange chamber 14 by means of tubular flow paths 16, 18. The ultrafiltration chamber may take any of a number of forms commonly used in the medical field. For purposes of illustration, the chamber is shown as comprising a generally rectangular enclosure 20 having upper and lower membranes 22 and 24, respectively, closely spaced apart from each other and supported by clamping structures 26 at opposite ends. The membranes open outwardly at their ends into manifolds 28, 30, respectively. A tubular cannula 29, which is preferably connected to the artery of a human or animcal body, receives blood from the body and carries it to the manifold 28. After passage through the narrow channel between the membranes 22, 24, the blood accumulates in manifold 30 and thereafter passes into the cellular exchange chamber 14 via conduit 18.
During its passage between the membranes, liquid constituents of the blood are forced outwardly through the one or both of the membranes to form an ultrafiltrate which collects within the interior of chamber 21. The ultrafiltrate is then drawn off into chamber 14 via conduit 16. Effectively, the reduced cross-sectional flow area between the membranes provides the requisite back pressure to support ultrafiltration action, while the source of blood provides the requisite positive pressure to do so.
Tubular conduits 16 and 18 continue as separate conduits within cellular exchange chamber 14 for separate exposure to exchange media 50 within the chamber. For purposes of illustration, chamber 14 is shown as a generally rectangular hollow chamber. The conduits themselves are formed from microporous semipermeable membranes whose pore size and wall thickness are such as to allow the transport of selected products across them, while effectively containing the fluid streams within them. For purposes of providing an artificial pancreas, the media 50 comprises pancreatic beta cells which provide a source of insulin in response to appropriate physiologic signals from the ultrafiltrate and the blood, respectively. Glucose and oxygen contained within the ultrafiltrate within conduit 16 permeate through the membraneous pores of this conduit into the medium 50 within the chamber 14, while insulin permeates through the pores in the reverse direction from the cellular medium 50 into the interior of the conduit 16 where it mixes with the insulin-containing ultrafiltrate within this conduit and is carried off with it. In like fashion, glucose and insulin are exchanged across the membraneous pores of conduit 18 between the blood within the conduit and the cellular exchange medium exterior to the conduit. Importantly, oxygen and other nutrients are transported across the pores of conduit 18 into the cellular medium 50 in order to sustain the beta cells. The conduits 16 and 18 are rejoined into a single conduit 52 at a transition junction 54. Conduit 52 returns the treated blood to the body, such as by connection into a vein.
The operation of the device of FIG. 1 is as follows: Arterial blood diverted from the body to be treated flows through tubular conduit 29 into ultrafiltration chamber 12 where it is separated into an ultrafiltrate component of essentially similar composition to the blood fluid, but lacking in proteins and blood cells, and a blood component containing these constituents. The ultrafiltration portion preferably provides a constricted path for the blood flowing into it in order to build up a suitable pressure to efficiently perform the ultrafiltration. It is expected that in most cases the human or animal body will provide sufficient pressure to support the requisite ultrafiltration portion pressure while continuing fluid blood flow through the device. Where this is not the case, it may be necessary to supplement the body-generated pressure by means of an auxilliary pumping device creating either a positive pressure on the inlet side (i.e., the side adjacent conduit 29) or creating a negative pressure on the outlet side (i.e., the side adjacent conduit 52). In either event, the resultant ultrafiltrate and whole blood component are passed along to the cell exchange chamber 14 via conduits 16 and 18, respectively, where they receive insulin through the tubular membraneous wall from the medium 50. On recombining in conduit 52, the insulin-containing ultrafiltrate and blood carry this insulin back to the body for utilization by it in controlling the glucose levels within the blood.
Turning now to FIG. 2, a first alternative embodiment in accordance with the present invention has the ultrafiltration chamber 12 serially connected to a cellular exchange chamber 14 as in FIG. 1. A conduit 70 carries ultrafiltrate from the ultrafiltration chamber to the cell chamber, while a conduit 18 carries the remaining whole blood component from chamber 12 to chamber 14. However, in contrast to FIG. 1, the conduit 70 does not continue into the chamber 14 in the form of a tubular semipermeable membrane as in FIG. 1 but, instead, discharges its contents directly into the cellular portion 50 for direct contact with the cellular exchange material (i.e., beta cells) therein. Also, as in the embodiment of FIG. 1, an inlet conduit 29 carries blood from the body, preferably from a high pressure location thereof such as an artery, and a conduit 72 carries the treated blood back to the body, preferably to a low pressure location thereof such as a vein. Again, however, unlike the embodiment of FIG. 1, the conduit 72 is continuous only with the conduit 18, and not with the conduit 70 as well. Thus, there is no direct protection between conduit 70 and conduit 72, in contrast to the embodiment of FIG. 1. Instead, the ultrafiltrate material supplied to the interior of chamber 14 obtains access to the conduit 72 only through diffusion through the semipermeable membrane pores of conduit 18. This diffusion is aided by the osmotic pressure difference between the pressure of the insulin-containing ultrafiltrate in chamber 14 and the reduced pressure of the blood component in conduit 18; the latter is at a lower hydrostatic pressure while maintaining colloid osmotic pressure. This results in a net fluid and solute flow from the insulin containing ultrafiltrate into the blood conduit according to the well-known principles of the Starling equilibrium of capillary exchange.
In another embodiment, the cells in the cellular exchange portion are microencapsulated in a microporous material (membrane) which prevents them from growing into the pores of the other microporous membranes. In this embodiment ultrafiltrate and blood may (optionally) directly mix together in the cellular exchange chamber.
Where the ultrafiltrate return rate to conduit 72 in FIG. 2 is insufficient to reach equilibrium under steady-state conditions, the filtration rate of ultrafiltrate into the conduit 72 may be increased by further decreasing the pressure in conduit 70 by means of a pump connected to this conduit. Alternatively, a bypass conduit 80 may be connected between chamber 14 and conduit 72 to carry additional ultrafiltrate directly from the chamber into the conduit 48. A semipermeable membrane 82 mounted on spacer blocks 84 connected to the interior walls of chamber 14 provides for passage of the ultrafiltrate from this chamber into conduit 72. A valve 86 allows for ajustment of the ultrafiltrate flow rate so that, under steady-state conditions, the rate at which ultrafiltrate is removed in chamber 12 from the blood being treated is the same as the rate at which the ultrafiltrate is being retrained to the conduit 72. The area and configuration of the membrane 82 and, correspondingly, the volume of the inlet chamber 80A, may be adjusted as appropriate to vary the ultrafiltrate return rate to conduit 80, and thus to conduit 72.
Turning now to FIG. 3, various alternatives for establishing the desired ultrafiltration flow-to-blood flow ratio are shown. In FIG. 3A, a shunt 90 bypasses a portion of blood from conduit 29 prior to its entrance into the ultrafiltration chamber 12. Accordingly, the production of ultrafiltrate is diminished by this arrangement and the ratio of ultrafiltrate to blood is correspondingly diminished. In FIG. 3B, a portion of the blood component exiting from chamber 12 is bypassed around the cell exchange chamber by means of a shunt conduit 92. This arrangement leaves intact the ratio of ultrafiltrate to whole blood established by the geometry of chamber 12 and the inlet and outlet pressures and flow rates therein, but varies the amount of blood contacting the exchange cells in chamber 14. Accordingly, its effect is equivalent to that of the increase in the ultrafiltration flow-to-blood flow ratio, although it decreases the total amount of blood exposed to the exchange cells. Finally, in FIG. 3C, a portion of the ultrafiltrate is bypassed around chamber 14 through a conduit 94 containing a valve 96 for controlling the flow in conduit 94, and may be returned to the blood and/or partially drained via an optional excretory duct. This embodiment leaves intact the actual ratio of ultrafiltration flow-to-blood flow generated by the ultrafiltrate chamber 12, but decreases the effective ratio of ultrafiltration flow-to-blood flow since it diminishes the amount of ultrafiltrate exposed to exchange cells in chamber 14.
So far I have described the preferred and various alternative embodiments of an artificial gland in accordance with my invention. The invention may also be extended to artificial organs, such as livers and kidneys, among others. As seen in FIG. 4, an artificial liver, for example, comprises a filtration chamber 12 receiving blood to be treated via a conduit 29 and applying it, after it has been ultrafiltered, through conduit 18 to a cell exchange chamber 100. A conduit 16 carries the ultrafiltrate to chamber 100. Conduit 18 extends through chamber 100 in the form of a multiply-looped coil formed from a semipermeable membrane retaining protein and other major blood constituents on the inside thereof for flow through the chamber within the conduit and returned to the body or other source through conduit 52 as was previously the case. During passage through chamber 100, the ultrafiltered blood exchanges various constituents with liver cells 102 within the chamber. Specifically, oxygen, certain nutrients, and waste products flow from the blood to the liver cells 102 within the chamber. These blood products sustain the liver cells, and also stimulate them to produce bile. Excretory products are then returned, via a conduit 104, to the urinary bladder or other parts of the urinary tract in the case of the kidney, or to the intestine, in the case of the liver. Alternatively, the conduit may lead to a collection bag outside the body.
From the foregoing, it will be seen that I have provided an improved hybrid artificial organ and gland. The device of the present invention provides an effective substitute for injured or diseased organs or glands more nearly approximating the rapid response of an actual body to acutely changing physiological demand and is expected to be capable of sustained functioning over extended periods of time. Various embodiments provide adjustment of the effective ratio of ultrafiltration flow to blood flow to adjust to differing body demands and an optional excretory channel is provided when appropriate for some organ modes.
It should also be understood that the term "pores" is used in a functional sense, in that some membranes without microscopically visible pores are capable of transporting substances by physically solubalizing them within the membrane and delivering them across the membrane. It should be understood that different types of cells may be used together for beneficial effect, e.g., mast cells that produce heparin which prevents clotting may be added to beta cells in the cellular exchange portion. Additionally, the cells may be frozen, grown in culture media, pretreated with chemicals or blood constituents such as antilymphocytic globulin to further aide in immunological protection, or treated in other ways promote their survival and longevity or improve their functional response.
It is further understood that the membraneous portions of the device may be employed in various configurations including, but not limited to, flat plates, coils, capillary tubes (woven and unwoven), singly, in multiples, and in various preferred combinations.
|Cited Patent
|Filing date
|Publication date
|Dec 29, 1969
|May 22, 1973
|Matsumura K
|Method and device for purifying blood
|May 16, 1973
|Aug 6, 1974
|Matsumura K
|Method and device of artificial endocrine pancreas
|Mar 17, 1975
|Mar 22, 1977
|Takeda Chemical Industries, Ltd.
|Multipurpose metabolic assist system
|Apr 22, 1975
|May 17, 1977
|Rhone-Poulenc Industries
|Artificial kidney
|Reach, G. et al., "Functional Evaluation of a Bioartificial Pancreas . . . " Diabetes, vol. 30, 4/1981, p. 296-301.
|Reach, G. et al., Functional Evaluation of a Bioartificial Pancreas . . . Diabetes , vol. 30, 4/1981, p. 296 301.
|Citing Patent
|Filing date
|Publication date
|Feb 7, 1991
|Dec 14, 1993
|Monsanto Company
|Biological artificial liver
|Dec 29, 1992
|Nov 29, 1994
|Hepatix, Inc.
|Organ support system
|Jul 1, 1996
|Feb 2, 1999
|The United States Of America As Represented By The Secretary Of Agriculture
|Artificial liver device
|Oct 31, 1997
|Mar 20, 2001
|Bucher-Guyer Ag
|Membrane module for a membrane separation system, its use and process for producing the same
|Apr 21, 2000
|May 13, 2003
|The Regents Of The University Of Michigan
|Extracorporeal fluid circuit and related methods
|Mar 28, 2003
|Jul 5, 2005
|Nephros Therapeutics, Inc.
|Extracorporeal fluid circuit and related methods
|Jun 16, 2004
|Nov 27, 2007
|Heritage Crystal Clean, Llc
|Portable filter system
|Mar 28, 2003
|Feb 5, 2004
|Weitzel William Frederick
|Extracorporeal fluid circuit and related methods
|Jun 16, 2004
|Dec 22, 2005
|Doug Larson
|Portable filter system
|Dec 22, 1993
|Jul 7, 1994
|Hepatix, Inc.
|Organ support system
|U.S. Classification
|210/137, 210/295, 210/259, 210/321.83
|International Classification
|Cooperative Classification
|European Classification
|Nov 1, 1993
|Fee payment
Year of fee payment: 4
|Nov 14, 1997
|Fee payment
Year of fee payment: 8
|Dec 4, 2001
|Maintenance fee reminder mailed
|May 10, 2002
|Surcharge for late payment
Year of fee payment: 11
|May 10, 2002
|Fee payment
Year of fee payment: 12


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text:
Wildly Charming Jewelry
Crafting Time:
- 3-5 Hours
Skill Level:
- Intermediate
Project Courtesy of: Advantus/Sulyn
Additional Information
- 2 Jewelry Fundamentals Acrylic Beads Card - Checks
- 3 Advantus/Sulyn 7 in. Large Round Faceted Glass Beads Strand – Onyx 1 Jewelry Fundamentals 12" Mini Crystalline Black Beads Strand
- 2 Jewelry Fundamentals 18"Chain Necklace Kit – Silver Finish
- 1 Jewelry Fundamentals Earring Assortment Pack
- Pliers (Roundnose & Needlenose)
- Make a total of 48 wire wrapped loop charms: 24 using the Mini Crystalline and Large Round Faceted Beads, 24 using the Mini Crystalline and Acrylic Beads.
- Starting at one of the larger links nearest the center of necklace, start attaching charms to the necklace using split rings from the Chain Necklace Kit.
- Attach 4 charms to each large link on the necklace for approximately 12 links.
- Remove clasps to shorten chain by 1" on each side. (May shorten more if desired.)
- Reattach the lobster clasp and jump ring.
- For each earring separate 3 segments of links from chain necklace as follows: 1-link section, 2-link section, and a 3-link section.
- Attach jump ring to chain sections and attach to earwire.
- Make 2 wire wrapped loop charms using Large Round Faceted and Mini Crystalline Beads.
- Make 1 wire wrapped loop charm using the Acrylic and Mini Crystalline Beads.
- Attach the 2 charms with the Large Round Faceted Beads to the 1-link and the 3-link sections of chain.
- Attach the remaining charm to the section of chain with 2 links.


text:
Smiller446 brauchte ein neues Logo Design und hat einen Wettbewerb auf 99designs gestartet.
Aus 134 Designs von 36 Designern wurde eine Gewinner gewählt.
A patient in a hospital may see multiple physicians during their stay. Our software selects a single physician as the most responsible physician from the group.
The attached file is our company logo. The Physician Attribution logo we are looking for is for one of our brands. We would like the color scheme to be similar to our current logo. Because our software selects a single physician from a group of physicians it might be nice to portray that in the logo, however we are completely open to all ideas. Our target audience would be executives of hospitals.


text: FXFactory Pro 5.0.6 (Mac OS X) | 52 MBFxFactory Pro includes filters, generators and transitions for Final Cut Pro X, Final Cut Pro 7, Motion, Premiere Pro and After Effects. FxFactory first extensible package of visual effects for Final Cut Studio. Unlimited capacity: download additional plug-ins in FxMarket. The user can check all the plug-ins and configure them suitably for your project, or create new ones based on existing ones. ? Create your own effects for Final Cut Studio without writing code. Seamless integration with FxPlug: once to install the plugin, you can immediately start using them in Final Cut Pro, Motion and After Effects. An additional advantage is that the Pro Pack plug-ins support the construction of a moving image of 16-bit and 32-bit. FxFactory its not just the built-in plugin manager, but also a complete environment for their management. Through it you can connect to the project the necessary modules, apply them to your content, preview and rendering. Requirements OS X Yosemite 10.10.2 or later Final Cut Pro 10.2 or later Motion 5.2 or later Adobe After Effects CC, CC 2014 and CC 2015 Versions 12, 13 and 14 Adobe Premiere Pro CC, CC 2014 and CC 2015 Versions 7, 8 and 9 Support for OX X El Capitan Link Download: Code: Download Via Nitroflare http://www.nitroflare.com/view/3C0ABD7A801CB84/fxf506Mac.part1.rar http://www.nitroflare.com/view/323D1096548EC60/fxf506Mac.part2.rar Download Via xxxxxxxx http://xxxxxxxx/1sv6rtvg http://xxxxxxxx/0ia1ds5i Download Via xxxxxxxx http://xxxxxxxx.net/file/be6e313a78770802b5a26d7ec3ea5abd/fxf506Mac.part1.rar.html http://xxxxxxxx.net/file/6ba848c9459778cb69efd1d9bed1ca91/fxf506Mac.part2.rar.html


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Date: 1965-05-30
Description: Exterior view of a leaning barn. Shadows from a farm machine fall on the barn's side wall in the early morning.
Date: 1922 ca.
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text:
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Robert Mittelstaedt, dean emeritus of ASU's W. P. Carey School of Business, feels that educators must combine business ethics and the humanities to produce graduates who will excel in their fields.


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The Company
Founded in 2002, Capital Novus (Capital Legal Solutions) is a leading global technology firm headquartered in Fairfax, VA, just outside of Washington, DC, with an exclusive focus on e-Discovery and information governance technology. As an industry pioneer, Capital Novus has developed innovative technical solutions for law firms, corporations and government agencies, meeting our customers needs for better, faster and more cost-efficient e-Discovery and information management solutions. Our suite of solutions is world class, and backed by an unparalleled engineering, development and training support team that delivers reliable and effective end results.
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text:
Kansas City Royals Signed Autographed Drew Butera 8"x10" Photo COA
$ 19.99
Product Details
Drew Butera caught the last out of the 2015 World Series! These officially licensed photos of the World Series celebration were signed by Drew at our signing with him at our store 10/4/16. Photos were signed in either silver or white ink. Multiple photos were signed so autograph placement may vary slightly.
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text:
Disciplinary Literacy and the Use of Context Clues
Three Compelling Questions
1. If context clues could be people, how would I recognize them?
2. What are context clues and how do I recognize them?
3. If I could give each type of context clue 2 personality traits, what traits would I choose for each type?
Types of Context Clues used for this class:
Root word and Affix
Example or illustration
Project Overview
Getting Started
Part I-Days 1 and 2
Students will view the video with a partner
Next step: Write about it!
After viewing the video students will explain what context clues are and how context clues may help them with reading comprehension. Students will explain what they think can be fun about using context clues in TodaysMeet. Then copy and paste your writing in this classroom under discussions.
Students, cut and paste in your browser a new open search page.
Students will work with a partner to find the meanings and specific jobs of our 6 types of context clues we are researching in this project by searching Context Clues on Kidtopia.
Students, cut and paste in your browser a new open search page.
Make a vocabulary card for each clue online and print them out at
http://www.timeforkids.com/homework-helper/study-helper/flashcard-maker **Students, cut and paste in your browser a new open search page.
Lastly for Part I:
Go to TodaysMeet and write about what you have learned about context clues. Explain how your idea has changed since you did your research. Then tell what you think can be fun about using context clues. Afterward copy and paste your notes from TodaysMeet into this classroom under discussions.
Disciplinary Literacy and the Use of Context Clues
Part II-Days 3 and 4
Students will personalize the types of context clues studied in this lesson. Working with a partner students will design (free draw or cut and paste) a character for each type of clue and give the character a special name that relates to the meaning of the context clue and give each character 2 personality traits (also representative of the context clue meaning or job within the text).
Examples of names and traits:
1. Root words and affixes-
Mr. Bark is adjustable and modifiable
2. Contrast
Mr. Colors is diverse and oppositional
3. Logical
Mr. Smarty is reasonable and understandable
4. Example and illustration
Mr. Creativity is artsy and valid
5. Grammar
Mr. Writing is elemental and structural
Home work for days 3 and 4
Go to:
Pick 3 activities and complete. After completing each one go to TodaysMeet and tell the class about your favorite one and how it helped you understand context clues better. Then copy and paste your comments in this classroom under discussions.
Project and Presentation -Publishing
Days 5 and 6
Students present on day 6
*Presentations will be video taped by Ms. G and graded by a peer team using our self-designed rubric
*Presentation videos will be posted here in our classroom for viewing by students and parents
Before the students begin designing a project around their context clue characters the class will work together to develop our grading rubric on RubiStar.
Your partner team will be grading another partner team using a rubric.
Guiding Questions:
What types of things should be graded during your presentation and your project development?
What categories do we need to include.
Suggestions: grammar, presentation skills, originality, neatness etc.
Example rubric:
**On TodaysMeet please explain how you felt about creating your own rubric. Why is it good? How do you feel about grading your peers?
Please copy and paste your TodaysMeet comments into this classroom under discussions.
**Video Posts:
Video posts will go here
Final Assessment Piece:
Please deeply read one article of your choice below: (a second article will be chosen later)
Highlight all unfamiliar words. Try to locate context clues and name what type you find. Explain how you understand the words based on the context.
http://www.readworks.org/sites/default/files/bundles/passages-koala-search-1_files.pdf#toolbar=[object BarProp]&view=FitH&navpanes=0&statusbar=0
http://www.readworks.org/sites/default/files/bundles/passages-talking-leaves_files.pdf#toolbar=[object BarProp]&view=FitH&navpanes=0&statusbar=0
http://www.readworks.org/sites/default/files/lessons/a_new_letter_for_the_alphabet_1040_passage_and_questions.pdf#toolbar=[object BarProp]&view=FitH&navpanes=0&statusbar=0
http://www.readworks.org/sites/default/files/passages/A%20Juicy%20Problem%20Passage_0.pdf#toolbar=[object BarProp]&view=FitH&navpanes=0&statusbar=0
http://www.readworks.org/sites/default/files/passages/840_321_blast_off_0.pdf#toolbar=[object BarProp]&view=FitH&navpanes=0&statusbar=0
Finally, Please take a survey below.
Course: ____________________________ Instructor Name: ____________________________
1. What do you like best about this course?
2. What would you like to change about the course?
3. What are the instructor's strengths?
4. What suggestions do you have to improve the instructor's teaching?


text:
The miserable economic performance of the past seven years has been blamed on many things, but one stands out: Dodd-Frank, the 2010 law that is now smothering banks and killing U.S. economic growth.
In their recent debate on MSNBC, both Hillary Clinton and Bernie Sanders bashed Wall Street and the banks, blaming them for the financial meltdown and subsequent record-slow economic recovery.
Sanders, a socialist, called Wall Street and the banks "criminal" and "corrupt" and implied that he would jail CEOs at big financial companies for their "illegal activity."
And Clinton issued a literal threat: "You know, we now have power under the Dodd-Frank legislation to break up the banks." Doubling down, she said that she now wants the same power over investment banks, insurance companies, mortgage companies and others.
Blaming banks and Wall Street might have populist appeal, but it's false. In his definitive analysis of the financial crisis, "Hidden In Plain Sight," Peter Wallison, who served on the Financial Crisis Inquiry Commission, showed that it was the systematic weakening of mortgage lending standards under the U.S. government's own housing policies that led to the meltdown -- and to the phony call by Democrats to go after Wall Street and the banks.
The 2010 Dodd-Frank bill, crafted from the Democrats' mythology, didn't solve any problems. Instead, it is at the heart of our current economic woes.
A new study by the Mercatus Center at George Mason University shows why. Dodd-Frank empowered the Federal Reserve to regulate banks as never before. As the chart shows, Fed regulatory restrictions due to Dodd-Frank have soared, from 80 in 2011 to 2,986 at the end of 2014. And there are more on the way.
The surge in regulation has had a devastating impact. It has added enormous new costs to banks, reducing lending. Economist Douglas Holtz-Eakin, who also served on the Financial Crisis Inquiry Commission, estimates that Dodd-Frank's regulatory siege will reduce GDP by $895 billion over the next 10 years, or about $3,346 per working person.
Meanwhile, Dodd-Frank's impact on small banks, once the engine of U.S. growth, has been equally pernicious.
Banking consultant Eric Grover of Intrepid Ventures recently wrote in The American Banker, "Under Dodd-Frank, new bank formation has essentially ceased." The data are shocking: From 2011 to 2014, just one new commercial bank and no new savings banks were chartered. In the 15 years before Dodd-Frank, an average of 140 new commercial banks and 15 new savings banks were chartered each year. While small banks are going out of business at a record rate due to regulatory costs, big banks with over $50 billion in assets are now "too big to fail."
Americans don't seem to know just how ill-served they were by the passage of the sweeping banking regulation bill in 2010. But Sanders and Clinton, contrary to their claims, are themselves guilty of fraud for perpetrating the lie that banks and Wall Street caused this mess. As supporters of Dodd-Frank, they should be ashamed.


text:
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