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Top Attractions in Inveraray, Argyll
The Duke of Argyll founded the town of Inveraray in 1745 and his ancestors still live in Inveraray Castle, one of the area's most popular attractions, to this day. The hotel makes a great base for exploring a selection of national parks, mountain ranges, lush gardens and a choice of beautiful islands, which are dotted across the water like a spectacular pearl necklace.
There are many other attractions close to the hotel and in the surrounding local area to choose from, whether you're on a romantic weekend break, a spa weekend, or an 'outdoorsy' holiday with the kids. Here are our top ten:
Crinan Canal
www.scottishcanals.co.uk / Tel: 01546 603210 (canal office)
The Crinan Canal links Loch Fyne at Ardrishaig with the sound of Jura, creating a waterway through the Kintyre peninsula in the heart of Argyll. Every year hundreds of boats make the journey along the nine miles of "Britain's most beautiful shortcut". Open all year. Suitable for the whole family.
Crarae Gardens
www.gardens-of-argyll.co.uk / Tel: 01546 886614
Near the banks of Loch Fyne, visit the UK's finest example of an exotic Himalayan-style woodland garden. The garden is open all year from 9.30am until sunset. Visitor centre open 10am - 5pm daily from 23March - 31July, and Monday - Friday from 1August - 31 October. Suitable for the whole family.
Adults £6.50 / Family £16.50 / Concessions £5.
Auchindrain Township Museum
www.auchindrain.org.uk / Tel: 01499 500235
Auchindrain is one of the last townships to survive and was in operation until 1963. The visitor centre has a shop and a tea room which is open 10am – 5pm daily from 1April – 31 October. Suitable for the whole family.
Adults £6.30 / Concession £5.20 / Children (aged 5-17) £3.60.
Inveraray Jail
www.inverarayjail.co.uk / Tel: 01499 302381
The jail provides an educational glimpse into the harsh living conditions of prisoners during the 19th Century. Open 9.30am – 6pm from April – October, and 10am – 5pm from November – March. Last admission is one hour before closing. Suitable for the whole family.
Adults £8.95 / Senior £7.50 / children (aged 5-17) £4.95.
Inveraray Castle
www.inveraray-castle.com / Tel: 01499 302203
The castle is the ancestral home of the Duke of Argyll, chief of the clan Campbell. This picturesque castle incorporates Baroque, Palladian and Gothic architecture and features four castellated towers at each corner. It is set in 16 acres, two of which are formal gardens. Downton Abbey fans will perhaps already know the castle was the chosen location for the Christmas episode in 2012. Open 10am – 5.45pm from 1 April – 31October. Suitable for the whole family.
Adults £10 / Concessions £9 / children (under 16) £7. Last admission is at 5pm.
Loch Fyne Oyster Bar
www.lochfyne.com / Tel: 01499 600264
This all started with one inspirational idea - to grow oysters in the clear, fertile waters of Loch Fyne - and has developed into a cluster of businesses whose success is built on an honest approach to superb quality food. Suitable for all oyster fans. Open 9am - 5pm Sunday to Thursday and 9am - 6pm on Fridays and Saturdays.
Loch Fyne Ales
www.fyneales.com / Tel: 01499 600120
The team at Fyne Ales brewery, shop and bar pride themselves on producing outstanding craft beer. If you like your ale, this is a must-visit! Open seven days a week 10am - 6pm.
Ardkinglas Woodlands
www.ardkinglas.com / Tel: 01499 600621
Located on the shores of Loch Fyne against a spectacular background of mountains and forests in the village of Cairndow, Ardkinglas Woodlands holds 'The world's tallest tree' record. Open all year round and suitable for all. Sturdy footwear is advisable.
Cruachan Power Station
www.visitcruachan.co.uk / Tel: 01866 822509
Hidden deep within the mountain of Ben Cruachan on the shores of Loch Awe is Cruachan Power Station. Here you can discover one of the wonders of the Highlands – a power station buried 1 kilometre below ground. At its centre lies a massive cavern high enough to house the Tower of London! Take a guided tour through the mountain then visit the cafeteria and gift shop. Open February – mid December.
Adults £6.50 / Concessions £5.50 / Children (aged 6-16) £2.50.
Inveraray Bell Tower
It takes 176 steps to reach to top of the ten-belled All Saints Bell Tower...but the beautiful views from the top will make all your efforts worthwhile. The bell tower rang to mark several special events during the 2012 Olympics and the Queen's Diamond Jubilee. It reopens in July 2014.
If you have any tourism queries, please feel free to contact us on 01499 302980 and we will do our best to help.


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Trevor B. Atchison, 21, of Alpha, Ill., who police say was shot in the head by his wife, was taken off life support Thursday and pronounced dead.
An autopsy was scheduled for Thursday afternoon in Peoria, according to the Henry County Sheriff's Department.
Additional charges are pending against Atchison's wife, Robin Carr Atchison, 29, of Alpha, Ill.
Charges have been filed against Atchison, accusing her of shooting her husband in the head early Tuesday. Authorities also have arrested a man they say illegally sold her the gun used in the shooting.
Trevor Atchison, 21, had been listed in critical condition Wednesday, one day after being shot by his wife with a .22-caliber rifle she allegedly purchased illegally from a Woodhull man, Henry County Sheriff Jim Padilla said.
Robin Atchison, as of Wednesday, is charged in Henry County Circuit Court with one count of reckless discharge of a firearm, a Class 3 felony under Illinois law that carries a prison sentence of two to five years. She also is charged with one count of being a felon in possession of a firearm, a Class 4 felony that carries a prison sentence of one to three years.
She was being held Wednesday night in the Henry County Jail on $500,000 bond.
More serious charges could be added after his death and as the investigation continues, authorities said.
According to Scott County Iowa District Court records, Robin Atchison pleaded guilty to a charge of second-degree theft in 2005. Her last name then was Carr. The charge is a Class D felony under Iowa law. She was sentenced to a three-year term on probation that she completed and paid restitution, fines and court costs of $2,709.09. The felony conviction precludes her from possessing a firearm.
Clint David Cole, 23, was arrested Wednesday and charged with one count of unlawful sale of a firearm to a felon. The charge is a Class 3 felony under Illinois law.
Cole was released from the Henry County Jail after posting 10 percent of a $50,000 bond.
Cole has a minimal criminal history that includes convictions in Henry County Circuit Court for being a minor in possession of alcohol, driving under the influence of alcohol and traffic violations.
Henry County sheriff's deputies responded to a 911 call for a shooting at 504 S. 1st St., Alpha, at 3:45 a.m. Tuesday. They found that Trevor Atchison had suffered a single gunshot wound to the head.
They took Robin Atchison into custody Tuesday morning.
The investigation is being conducted by the Henry County Sheriff's Department.

subset: commoncrawl


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The chief executive of AstraZeneca, David Brennan, shocked the markets by announcing his resignation yesterday in an apparent boardroom coup just hours before the pharmaceuticals giant's shareholder meeting kicked off.
Mr Brennan's departure appeared to be a victory for investors who had called for change at the top of the FTSE 100 drugs giant, which is suffering from dramatically falling revenues as key drugs face generic competition, as well as a weak pipeline of new drugs.
Yesterday the drug maker added a profits warning to its other woes. Its first-quarter pre-tax profit plunged 40 per cent to $2.05bn (£1.26bn) – well below City expectations – but it admitted the full-year profit would also be worse.
One investor at the AGM at a London hotel shouted "shame on you" to Astra's board for "sniping" at Mr Brennan in newspaper stories, complaining about his lack of leadership as revenues began drying up. Another said the drug maker's performance targets should be "more demanding" as "too much money" was thrown at executives.
Mr Brennan, an American who started his career selling blood-pressure pills to doctors in Jersey City, pocketed a £9.1m salary last year.
Britain's second-biggest drug maker said Mr Brennan had told the board of his departure only yesterday. Instead of serving out his 12-month notice, he will retire on 1 June and be replaced, temporarily, by the finance director, Simon Lowth.
In addition, Leif Johansson, the former Volvo boss who is to succeed Louis Schweitzer as chairman, will take over three months earlier than planned, also on 1 June.
Although Mr Johansson only joined the board this week, some people close to Astra said he was closely involved in the decision that Mr Brennan should go sooner rather than later. "Having someone in a lame-duck position wasn't consider helpful," a source close to the board told Reuters.
Astra said Mr Brennan's departure terms had not yet been decided but he could pocket £1m – a year's basic salary – as part of a pay-off package.
Mr Brennan said yesterday: "I have decided that now is the right time to step down and allow a new leader to take the reins."
The 58-year-old replaced Sir Tom McKillop in AstraZeneca's top job in 2006. The company was already well aware of the creeping patent expiries that would wipe billions off its annual revenues. Mr Brennan reacted by slashing jobs – it is set to get rid of 12 per cent of its 60,000 workforce by 2014 – and going on a shopping spree.
But the M&A strategy, including the troublesome $15.6bn deal to buy MedImmune in 2007, failed as the acquired firms' new drugs faltered at trials. In recent months three drugs earmarked for their potential have all failed and then been dumped after drugs trials.
Meanwhile, the patent problems remain. Seroquel, Astra's antipsychotic drug that accounted for sales of $5.3bn last year, came out of patent in the key US market last month. The cholesterol-buster Crestor, AstraZeneca's best-selling drug, faces generic rivals from 2016.
Shares in AstraZeneca fell more than 6 per cent or 174.5p to 2,666.5p.
- More about:
- Drugs
- Investment
- Pharmaceuticals


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MammaPrint Shows Which Breast Cancer Patients Can Skip Chemo »
"A huge European trial has shown that the 70-gene assay MammaPrint can identify patients with early breast cancer who can safely skip adjuvant chemotherapy, even if they have clinical characteristics suggesting they are at high risk.
Read the MammaPrint Shows Which Breast Cancer Patients Can Skip Chemo article »
Risk Of Bleeding
Because FASLODEX is administered intramuscularly, it should be used with caution in patients with bleeding diatheses, thrombocytopenia, or anticoagulant use.
Increased Exposure In Patients With Hepatic Impairment
The safety and pharmacokinetics of FASLODEX were evaluated in a study in seven subjects with moderate hepatic impairment (Child-Pugh class B) and seven subjects with normal hepatic function. Exposure was increased in patients with moderate hepatic impairment, therefore a dose of 250 mg is recommended [see DOSAGE AND ADMINISTRATION].
FASLODEX has not been studied in patients with severe hepatic impairment (Child-Pugh class C) [see Use in Specific Populations].
Embryo-Fetal Toxicity
Based on findings from animal studies and its mechanism of action, FASLODEX can cause fetal harm when administered to a pregnant woman. In animal reproduction studies, administration of fulvestrant to pregnant rats and rabbits during organogenesis resulted in embryo-fetal toxicity at daily doses that are significantly less than the maximum recommended human dose. Advise pregnant women of the potential risk to a fetus. Advise females of reproductive potential to use effective contraception during treatment with FASLODEX and for one year after the last dose [see Use in Specific Populations and CLINICAL PHARMACOLOGY].
Patient Counseling Information
Advise the patient to read the FDA-approved patient labeling (PATIENT INFORMATION)
Risk of Bleeding
- Because FASLODEX is administered intramuscularly, it should be used with caution in patients with bleeding disorders, decreased platelet count, or in patients receiving anticoagulants (for example, warfarin) [see WARNINGS AND PRECAUTIONS].
Embryo-Fetal Toxicity
- Advise females of reproductive potential of the potential risk to a fetus and to use effective contraception during treatment with FASLODEX and for one year after the last dose. Advise females to inform their healthcare provider of a known or suspected pregnancy [see WARNINGS AND PRECAUTIONS and Use In Specific Populations].
- Advise women not to breast-feed during treatment with FASLODEX and for one year after the last dose [see Use in Specific Populations].
Combination Therapy with Palbociclib
See palbociclib full prescribing information for Patient Counseling Information.
Nonclinical Toxicology
Carcinogenesis, Mutagenesis, Impairment Of Fertility
Two-year carcinogenesis studies were conducted in rats and mice. Positive findings were observed in both species. Rats were treated at intramuscular doses of 15 mg/kg/30 days, 10 mg/rat/30 days and 10 mg/rat/15 days.
These doses correspond to 0.9-, 1.5-, and 3-fold (in females) and 0.8-, 0.8-, and 2-fold (in males) the systemic exposure [AUC0-30 days] achieved in women receiving the recommended dose of 500 mg/month. An increased incidence of benign ovarian granulosa cell tumors and testicular Leydig cell tumors was evident, in females dosed at 10 mg/rat/15 days and males dosed at 15 mg/rat/30 days, respectively. Mice were treated at oral doses of 0, 20, 150 and 500 mg/kg/day. These doses correspond to 0, 0.8, 8.4 and 18-fold (in females) and 0.8-, 7.1- and 11.9- fold (in males), the systemic exposure (AUC0-30 days) achieved in women receiving the recommended dose of 500 mg/month. There was an increased incidence of sex cord stromal tumors (both benign and malignant) in the ovary of mice at doses of 150 and 500 mg/kg/day. Induction of such tumors is consistent with the pharmacology-related endocrine feedback alterations in gonadotropin levels caused by an antiestrogen.
Fulvestrant was not mutagenic or clastogenic in multiple in vitro tests with and without the addition of a mammalian liver metabolic activation factor (bacterial mutation assay in strains of Salmonella typhimurium and Escherichia coli, in vitro cytogenetics study in human lymphocytes, mammalian cell mutation assay in mouse lymphoma cells and in vivo micronucleus test in rat).
In female rats, fulvestrant administered at doses ≥ 0.01 mg/kg/day (0.6% the human recommended dose based on body surface area [BSA in mg/m²]), for 2 weeks prior to and for 1 week following mating, caused a reduction in fertility and embryonic survival. No adverse effects on female fertility and embryonic survival were evident in female animals dosed at 0.001 mg/kg/day (0.06% the human dose based on BSA in mg/m²). Restoration of female fertility to values similar to controls was evident following a 29-day withdrawal period after dosing at 2 mg/kg/day (equivalent to the human dose based on BSA in mg/m²). The effects of fulvestrant on the fertility of female rats appear to be consistent with its antiestrogenic activity. The potential effects of fulvestrant on the fertility of male animals were not studied but, in a 6-month toxicology study, male rats treated with intramuscular doses of 15 mg/kg/30 days, 10 mg/rat/30 days, or 10 mg/rat/15 days fulvestrant showed a loss of spermatozoa from the seminiferous tubules, seminiferous tubular atrophy, and degenerative changes in the epididymides. Changes in the testes and epididymides had not recovered 20 weeks after cessation of dosing. These fulvestrant doses correspond to 1.3-, 1.2- and 3.5-fold the systemic exposure [AUC0-30 days] achieved in women receiving the recommended dose of 500 mg/month.
Use In Specific Populations
Risk Summary
Based on findings from animal studies and its mechanism of action, FASLODEX can cause fetal harm when administered to a pregnant woman [see CLINICAL PHARMACOLOGY]. There are no available data in pregnant women to inform the drug-associated risk. In animal reproduction studies, administration of fulvestrant to pregnant rats and rabbits during organogenesis caused embryo-fetal toxicity, including skeletal malformations and fetal loss, at daily doses that were 6% and 30% of the maximum recommended human dose based on mg/m², respectively [see Data]. Advise pregnant women of the potential risk to a fetus.
The estimated background risk of major birth defects and miscarriage for the indicated population is unknown. In the U.S. general population, the estimated background risk of major birth defects and miscarriage in clinically recognized pregnancies is 2-4% and 15-20%, respectively.
Animal Data
Administration of fulvestrant to rats prior to and up to implantation caused embryonic loss at daily doses that were 0.6% of the daily maximum recommended human dose based on mg/m². When fulvestrant was administered to pregnant rats during the period of organogenesis, intramuscular doses ≥ 0.1 mg/kg/day (6% of the human recommended dose based on mg/m²) caused effects on embryo-fetal development consistent with its antiestrogenic activity. Fulvestrant caused an increased incidence of fetal abnormalities in rats (tarsal flexure of the hind paw at 2 mg/kg/day; equivalent to the human dose based on mg/m²) and non-ossification of the odontoid and ventral tubercle of the first cervical vertebra at doses ≥ 0.1 mg/kg/day. Fulvestrant administered at 2 mg/kg/day caused fetal loss.
When administered to pregnant rabbits during the period of organogenesis, fulvestrant caused pregnancy loss at an intramuscular dose of 1 mg/kg/day (equivalent to the human dose based on mg/m²). Further, at 0.25 mg/kg/day (30% the human dose based on mg/m²), fulvestrant caused increases in placental weight and post-implantation loss in rabbits. Fulvestrant was associated with an increased incidence of fetal variations in rabbits (backwards displacement of the pelvic girdle, and 27 pre-sacral vertebrae at 0.25 mg/kg/day; 30% the human dose based on mg/m²) when administered during the period of organogenesis.
Risk Summary
There is no information regarding the presence of fulvestrant in human milk, nor of its effects on milk production or breast-fed infant. Fulvestrant can be detected in rat milk [see Data]. Because of the potential for serious adverse reactions in breast-fed infants from FASLODEX, advise a lactating woman not to breast-feed during treatment with FASLODEX and for one year after the final dose.
Levels of fulvestrant were approximately 12-fold higher in milk than in plasma after exposure of lactating rats to a dose of 2 mg/kg. Drug exposure in rodent pups from fulvestrant-treated lactating dams was estimated as 10% of the administered dose. In a study in rats of fulvestrant at 10 mg/kg given twice or 15 mg/kg given once (less than the recommended human dose based on mg/m²) during lactation, offspring survival was slightly reduced.
Females And Males Of Reproductive Potential
Pregnancy Testing
Pregnancy testing is recommended for females of reproductive potential within seven days prior to initiating FASLODEX.
FASLODEX can cause fetal harm when administered to a pregnant woman. Advise females of reproductive potential to use effective contraception during treatment and for one year after the last dose.
Based on animal studies, FASLODEX may impair fertility in females and males of reproductive potential. The effects of fulvestrant on fertility were reversible in female rats [see Nonclinical Toxicology].
Pediatric Use
Safety and effectiveness in pediatric patients have not been established. A multi-center, single-arm, open-label, study of fulvestrant was conducted in 30 girls with McCune-Albright Syndrome (MAS) associated with progressive precocious puberty (PPP). The median age at informed consent was 6 years old (range: 1 to 8).
The first 10 patients initially received fulvestrant 2 mg/kg. Based on PK data from the first 6 patients, all 10 patients receiving 2 mg/kg were escalated to a dose of 4 mg/kg and all other patients received 4 mg/kg from study entry.
Baseline measurements for vaginal bleeding days, bone age, growth velocity, and Tanner staging for at least 6 months prior to study entry were provided retrospectively by the parent, guardian or local consultant. All measurements during the study period were collected prospectively. Patients' baseline characteristics included the following: a mean ± SD chronological age of 5.9 ± 1.8 years; a mean rate of bone age advancement (change in bone age in years divided by change in chronological age in years) of 2.0 ± 1.03; and a mean growth velocity z-score of 2.4 ± 3.26.
Twenty-nine of 30 patients completed the 12-month study period. The following results were observed: 35% (95% CI: 16%, 57%) of the 23 patients with baseline vaginal bleeding experienced a complete cessation of vaginal bleeding on-treatment (month 0 to 12); a reduction in the rate of bone age advancement during the 12-month study period compared to baseline (mean change = -0.9 [95% CI: -1.4, -0.4]); and a reduction in mean growth velocity Z-score on-treatment compared to baseline (mean change = -1.1 [95% CI: -2.7, 0.4]). There were no clinically meaningful changes in median Tanner stage (breast or pubic), mean uterine volume, or mean ovarian volume, or predicted adult height (PAH) on-treatment compared to baseline. The effect of FASLODEX on bone mineral density in children has not been studied and is not known.
Eight patients (27%) experienced adverse reactions that were considered possibly related to FASLODEX. These included injection site reactions (inflammation, pain, hematoma, pruritus, rash), abdominal pain, contusion, tachycardia, hot flush, extremity pain, and vomiting. Nine (30.0%) patients reported an SAE, none of which were considered related to FASLODEX. No patients discontinued study treatment due to an AE and no patients died.
The pharmacokinetics of fulvestrant was characterized using a population pharmacokinetic analysis with sparse samples per patient obtained from 30 female pediatric patients aged 1 to 8 years with PPP associated with MAS. Pharmacokinetic data from 294 postmenopausal women with breast cancer who received 125 or 250 mg monthly dosing regimen were also included in the analysis.
In these pediatric patients receiving 4 mg/kg monthly intramuscular dose of fulvestrant, the geometric mean (SD) CL/F was 444 (165) mL/min which was 32% lower than adults. The geometric mean (SD) steady state trough concentration (Cmin,ss) and AUCss was 4.19 (0.87) ng/mL and 3680 (1020) ng*hr/mL, respectively.
Geriatric Use
For FASLODEX 250 mg, when tumor response was considered by age, objective responses were seen in 22% and 24% of patients under 65 years of age and in 11% and 16% of patients 65 years of age and older, who were treated with FASLODEX in Study 2 and Study 3, respectively.
Hepatic Impairment
FASLODEX is metabolized primarily in the liver.
The pharmacokinetics of fulvestrant were evaluated after a single dose of 100 mg in subjects with mild and moderate hepatic impairment and normal hepatic function (n = 7 subjects/group), using a shorter-acting intramuscular injection formulation. Subjects with mild hepatic impairment (Child-Pugh class A) had comparable mean AUC and clearance values to those with normal hepatic function. In subjects with moderate hepatic impairment (Child-Pugh class B), the average AUC of fulvestrant increased by 70% compared to patients with normal hepatic function. AUC was positively correlated with total bilirubin concentration (p = 0.012). FASLODEX has not been studied in patients with severe hepatic impairment (Child-Pugh class C).
A dose of FASLODEX 250 mg is recommended in patients with moderate hepatic impairment (Child-Pugh class B) [see DOSAGE AND ADMINISTRATION and WARNINGS AND PRECAUTIONS].
Renal Impairment
Negligible amounts of fulvestrant are eliminated in urine; therefore, a study in patients with renal impairment was not conducted. In the advanced breast cancer trials, fulvestrant concentrations in women with estimated creatinine clearance as low as 30 mL/min were similar to women with normal creatinine.This monograph has been modified to include the generic and brand name in many instances.
Last reviewed on RxList: 3/9/2016
Faslodex FDA Prescribing Information
Additional Faslodex Information
Faslodex - User Reviews
Faslodex User Reviews
Now you can gain knowledge and insight about a drug treatment with Patient Discussions.
Here is a collection of user reviews for the medication Faslodex sorted by most helpful.
Report Problems to the Food and Drug Administration
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit the FDA MedWatch website or call 1-800-FDA-1088.
Breast Cancer
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SUN readers have voted Celebrity Big Brother housemate Julian Clary as their
favourite to win the show.
Over 11,000 votes were cast in the online poll.
Comedian Julian snared 27 per cent of the overall numbers, beating The
Situation into second place with 24 per cent of the tally.
Former EastEnders star Martin Kemp grabbed 20 per cent, while Loose Women
presenter Coleen Nolan nabbed 13 per cent.
Trailing behind them is judo ace Ashley McKenzie with 10 per cent, while MC
Harvey has picked up a measley 6 per cent of the votes.
Clary is also the bookies' favourite to win.
Ladbrokes have slashes the odds of Julian to pick up the prize – giving him
odds of 1/2.
Martin Kemp is in second place with 7/2, followed by Coleen at 7/2.
Once again MC Harvey is trailing behind with odds of 66/1.


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Jan 29, 2008 | 272 Pages
"An action-packed plot, rich period detail, and a bit of romance will insure that readers of cozies and historical mysteries will find much to enjoy."
"Langley-Hawthorne follows in the pertly trod path set by Jacqueline Winspear. . . . Consequences of Sin is more Dorothy Sayers than CSI, which isn't a bad thing at all."
-Joanne Sasvari, Calgary Herald


text:
e n d i n g
{e n d}
to beatrice:
the white in your hair
is stardust
{and snow and lilies
and bright, bright glory}
to beatrice:
do not believe that the lock on your heart
will rust;
one day, you will break it open
and find there is only love inside and
not dust
{a key lost is a key waiting to be found.
remember that.}
to beatrice:
you do not need to fit
into this world;
the world needs to wrap its arms
around you
and cradle you
just as you deserve
{it's your world too,
my dear}
to beatrice:
may the light fall on your head
so the world can see you
for what you are
{i see angels, i see stars,
i see joy}
to beatrice:
may the breeze hold you tight
so that you know, i'm never far
just look to the sky.
to beatrice:
there is no treasure
like light in your eyes
or the curve of your smile.
i love you still
and always will.
happy birthday.


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This simple, water-based gel moisturizer is ideally for oily skin. It contains a mix of vitamins A and E along with glycerin, a gel-based thickening agent, and preservatives. We suppose it's an OK, affordable option if you're curious to see what these antioxidant vitamins will do for your skin, but neither is going to eliminate dry, aging skin as claimed. If anything, the lack of emollients in this moisturizer will assuredly leave those with dry skin wanting more. Regrettably, Derma-E also included "natural fragrant oils". This ingredient generalization leaves consumers in the dark about which oils they're applying to their skin, not to mention the designation isn't one that's supported by any cosmetics regulatory agency in the world. If a cosmetics company can't get this right, how are consumers supposed to trust other aspects of their formulas?
This easily absorbed oil-free cooling gel helps diminish the appearance of lines and wrinkles caused by the sun and aging. It adds no oil to your skin, only healing nutrients, and is an excellent problem skin treatment. Leaves your skin feeling soft, smooth and supple.
Purified Water (Aqua), Carthamus Tinctorius (Safflower) Seed Oil, Glycerin, Stearic Acid, Glyceryl Stearate SE, Cetyl Alcohol, Persea Gratissima (Avocado) Oil, Sesamum Indicum (Sesame) Seed Oil, Helianthus Annus (Sunflower) Seed Oil, Retinyl Palmitate (Vitamin A), Glycine Soja (Soybean) Oil, Panthenol (Provitamin B5), Tocopheryl Acetate (Vitamin E), Allantoin, Cedrus Atlantica (Cedarwood) Essential Oil, Phenylethyl Alcohol, Vanillin, Carbomer, Phenoxyethanol, Ethylhexylglycerin.
Derma E At-a-Glance
Strengths: Inexpensive considering the formulas; company provides complete ingredient lists on their Web site; an effective AHA product; tea tree oil–based disinfectants for acne; some good cleansers and a good toner; well-formulated mask.
Weaknesses: Jar packaging is rampant for many of the antioxidant-rich products; several boring moisturizers; abrasive scrubs; one skin-lightening product with questionable efficacy; products that contain the controversial ingredient DMAE; several products contain natural ingredients that have not been proven effective for their intended purpose; the anti-aging products with peptides make over-the-top claims not supported by what they contain.
"Formulated for results" and "We're serious about skin care" are phrases you'll see throughout the Derma E line—that and a heavy accent on all things natural. In business since 1984, this California-based, family-owned skin-care company's products are often seen in health food stores. We suspect the numerous questions we've been asked about the Derma E line are tied not only to their use of natural ingredients, but also to their emphasis on antioxidants, which they include in almost every product. In many cases, there are antioxidants aplenty; however, more often than not, the choice of jar packaging spoils the benefit the antioxidants Derma E chose could provide (air-tight packaging is critical because antioxidants deteriorate in the presence of air).
More so than any other line weve reviewed so far, where packaging is critical to ingredient efficacy and stability, Derma E has seemingly turned a blind eye to this glaring error. Because of that, there are very few products to extol or recommend, even though the line is priced fairly and some of the products have good formulations. But, just as you shouldn't eat food that no longer has any nutritional properties, the same goes for skin care, why bother if your skin isn't getting what it needs to be healthy?
The company's founders talk openly about their commitment to formulating quality products, often using proprietary ingredients (meaning ingredients unique to Derma E). Yet a quick look at the ingredients on the label shows that isn't true. Even if it were true, the notion that you would be getting something better for skin is sheer nonsense. There are lots of brilliant ingredients for skin available in the cosmetics world, and there is no single company that has a secret lurking in its laboratory that is a must for skin. It can be a very compelling story unless you know better, and if you don't already know better, you will after reading the reviews. Product after product either disappoints or comes in below average based on packaging issues or on problematic natural ingredients, the claims for which are based on folklore and anecdotal experience, not on solid science.
It all gets rather muddled where Derma E is concerned because several of their anti-aging products do contain some interesting peptides and impressive amounts of antioxidants. In many respects, the antioxidants chosen have reliable track records when it comes to their skin-care benefits. But again, jar packaging sabotages these performance-based ingredients to the point that it's difficult to take anything else the company does seriously. After all, if they can't get this fundamental right, what's the point of continually talking up their commitment to results-oriented products?
It doesn't seem that sun protection is very high on Derma E's priority list either. You'll find moisturizers and eye creams galore, including many with antiwrinkle and skin-firming claims—but only one sunscreen. One. In the entire line. And, surprise, it doesn't contain natural sunscreen agents, at least not entirely. It never ceases to amaze me when "natural" product companies choose synthetic sunscreen actives when there are natural alternatives such as zinc oxide or titanium dioxide. Synthetic sunscreens are perfectly fine, but if you're going to shout natural from the rooftops, why are you using synthetic sunscreen actives? Plus, any line that touts their anti-aging, antiwrinkle prowess should have more than one sunscreen. Walking away from the store after buying products only from this line is a guarantee you will be cheating your skin.
A common falsehood, perpetuated by Derma E and by many other cosmetics companies, is that their products are "natural" (whatever that truly means). Rest assured that that's about as probable as sandy, warm beaches in Antarctica (or a snowball in Hades). Derma E products contain many natural ingredients, but plenty of synthetic ingredients have been cast in major or supporting formulary roles. For example, Linda Miles, one of Derma E's founders, has stated that the company won't use the natural version of alpha lipoic acid because it is "a butcher house by-product," meaning it's derived from animals. She admits the company uses synthetic alpha lipoic acid, however, and she must be unaware that alpha lipoic acid need not be derived from meat; it also can be derived from spinach, carrots, broccoli, potatoes, yams, and yeast, all of which are very natural and, of course, not derived from animal flesh (Sources: www.naturaldatabase.com; and The Rose Sheet, May 26, 2008, page 4).
Miles also admitted that Derma E has struggled to find a good preservative system to replace the synthetic ones they currently use. That's not surprising, as it's an issue that any line that wants to go natural must deal with; the reality is that there are no natural preservatives that work as well in low amounts as the synthetic options.
We could go on about Derma E's claims in terms of what they do and don't use and will and won't do, but you've heard it all before from other natural lines. As is usually the case, there are some standout products to consider from Derma E. If the company overhauled its packaging to improve antioxidant stability, the handful of products would become a basket's worth, but there is no word on whether such a change is happening or even in the works.
For more information about Derma E, call (800) 521-3342 or visit www.dermae.com.
The Beautypedia and Paula's Choice Research teams have one mission: To help you find the best products for your skin, whether they're from Paula's Choice or another brand. By combining efforts, we're able to share scientific research and remain committed to the highest standards based on our decades of experience objectively reviewing thousands upon thousands of skincare and makeup formularies in all price ranges.
Beautypedia cuts through the hype to bring you product insights and recommendations you won't find anywhere else!


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Office Assistant
ConfidentialLos Angeles, CA
Don't worry we have a lot of jobs on the site like this one;
Browse all jobs
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Full Time Job
Los Angeles based music production/publishing company is looking for an enthusiastic, self-starter who is very detail oriented with strong communication skills and the ability to learn fast.
Various duties and responsibilities would include but are not limited to: cue registrations with various publishing rights organizations (ASCAP,BMI, SESAC), creating client newsletters, catalog distribution to various sub-publishers and clients, assisting other team members with tasks, salesforce updates, preparing hard drives for clients, updating our licensing database, creating metadata templates and spreadsheets, overseeing office supply orders, answering phones, researching potential clients and new composers, as well as additional office duties when necessary.
The ideal candidate should be familiar microsoft excel and office word along with technology and resources related to the music and entertainment industries, such as various audio file formats and conversions, tagging audio files, media distribution and file transfers. Previous experience with Source Audio platform is also a huge plus but not necessary. Chosen candidate must have reliable transportation.


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Thank you for sending an invite to Lieutenant Governor Mallott. While your issue is important, please understand the Lieutenant Governor receives numerous meeting requests and as such his schedule is unable to accommodate every request received.
The Lieutenant Governor's schedule is subject to change. Occasionally it may be necessary to cancel a previously confirmed meeting. Every effort will be made to immediately contact the person listed below of a change in schedule. Additionally, if the Lieutenant Governor is unable to meet, our office may arrange for a designee to attend on his behalf.
If you have questions regarding our scheduling process, please feel free to contact the Lieutenant Governor's scheduler at 907-465-3520.
Please complete the form below. In order to better process your request, please provide as much information as possible.
I look foward to meeting with you.
Byron Mallott


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Complete Details About Start.myplaycity.com Threat:
If your computer browser homepage is suddenly replaced with the unknown domain which is called of Start.myplaycity.com, it means that your computer is infected with the potentially unwanted program (PUP). It starts to bombard numerous pop-ups and advertisements in order to misguide your browsing experience as well as redirection of your web page results. You don't have proper knowledge to get away this malign program from your PC. Thus, you are advised to read the given below article carefully and follow their automatic or manual removal process to get rid of Start.myplaycity.com from your PC.
What is Start.myplaycity.com and its demerits?
As the category of browser hijacker family, Start.myplaycity.com is one the precarious computer infectious program which contains the insecure code with aiming causes more and more issues on your PC. It has ability to secretly attacks on targeted victims PC in order to causes redirection issues and organizes the several malignant tasks without seeking permission and knowledge. Apart from these, it has ability to contaminate your famous and legitimate working web browser including Mozilla, Opera, UC, IE and Microsoft Edge. After that, it interrupts your browsing session by the claiming that your computer is infected with some nasty threats. You can get away this nasty infection from your PC via the updating of your software like media player, adobe reader, flash player, java scripts and etc. In reality, it is only bogus alerts which aim is to lure innocent user for the hunting of their privacy and data.
Start.myplaycity.com has been crafted by the group of cyber criminals whose main objective is to boost up their web traffic as well as Google page ranking by the cheated of innocent user privacy like browsing history, cookies, login id password, bank account details and others. What's more, it even accesses the backdoor of System in order to invades the other computer threats like Trojan, spyware, adware, ransomware and etc. besides, it has ability to eat up the high resources of PC settings in order to further errors continuously and get down your PC performance very badly. So, it is strongly advised to delete Start.myplaycity.com instantly from your PC.


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- Explore community
- Identify
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Added: 11th August 2011
Approximate date of observation. This fairly small tree was growing in a populated hilly area alongside a public footpath. It was not in a park or garden, but the habitat option is the nearest to where I actually found the plant. I am assuming the Chinese Juniper because of the colour of the mature fruits.


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It only takes a minute to get started. Fill out our uncomplicated sign up form and login to the website.
This step is voluntary but will greatly enhance your chances of your profile getting read by other members. Tell people about yourself, your pasttimes and upload a nice photo of yourself.
Use our website's advanced search to discover members who meet your criteria. Or just browse through listings and discover members that seem interesting.
Located someone who takes your fancy? Send a letter to them or just a wink and see what they say. With a little luck you'll be on your way to locating your proper match.
It only takes a few minutes


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Wellco Holdings Corp (7831.T)
9:14pm EDT
¥-2 (-1.23%)
Latest Key Developments (Source: Significant Developments)
Wellco Holdings says capital alliance with Creative Platform Group
Wellco Holdings Corp <7831.T> : Says it will acquire 258,700 shares of Creative Platform Group Co., Ltd.<7814.T> , at the price of 685 yen per share, 177.2 million yen in total . Says it will hold 2.95 percent shares of Creative Platform Group Co., Ltd. . The payment date on April 28 .Says Creative Platform Group Co., Ltd. will acquire 1.2 million shares (4.9 percent stake ) of the company on April 12. Full Article
Wellco Holdings to fully buy WITH CORPORATION and units for 795.5 mln yen
Wellco Holdings Corp <7831.T>: Says it plans to buy 100 percent stake in WITH CORPORATION for 795.5 million yen(advisory fees included) . Says WITH CORPORATION is mainly engaged in SP tools and speech recognition modules business . Says the three wholly owned units of WITH CORPORATION will be also transferred the co after the acquisition .Says effective date on Aug. 31. Full Article
Wellco Holdings unit to set up JV in Thailand with T.K.S. Siam Press Management
Wellco Holdings Corp:Unit to set up JV in Thailand with T.K.S. Siam Press Management, in late April.Unit to hold 51 pct stake in the JV.JV to be engaged in production of label without layer. Full Article
Wellco Holdings raises year-end dividend forecast for FY 2016
Wellco Holdings Corp:Says it raised the year-end dividend forecast to 4 yen per share from 3 yen per share for the fiscal year ending Oct. 2016. Full Article
Wellco Holdings to issue year-end dividend for FY 2015
Wellco Holdings Corp:To issue a year-end dividend of 3 yen per share to all the shareholders of record as of Oct. 31, for FY ended Oct. 2015.Payment date Jan. 29, 2016.Says latest dividend forecast was 3 yen per share. Full Article
Wellco Holdings raises year-end dividend forecast for FY 2015
Wellco Holdings Corp:Raised year-end dividend forecast to 3 yen per share from 2 yen per share for FY ended Oct. 2015. Full Article
Wellco Holdings amends consolidated full-year outlook for FY 2015
Wellco Holdings Corp:Says the company lowered the consolidated full-year outlook for revenue to 14,000 million yen from 17,000 million yen for FY ending Oct. 2015.Operating profit forecast increased to 300 million yen from 180 million yen.Ordinary profit forecast increased to 320 million yen from 200 million yen.Net profit forecast increased to 400 million yen from 170 million yen.Earnings per share increased to 16.26 yen from 6.91 yen.Comments the sales decrease and extraordinary profit are the main reasons for the forecast. Full Article
Wellco Holdings announces settlement of lawsuit and expects extraordinary loss for FY 2015
Wellco Holdings Corp:Reached settlement with HAKUHODO Inc, regarding a lawsuit disclosed on Feb. 1, 2012.To pay 120 mln yen to HAKUHODO by Sep. 30.Expects extraordinary loss of 104 mln yen for FY 2015. Full Article
Wellco Holdings to sell shares of wholly owned subsidiary
Wellco Holdings Corp:To sell 200 shares of wholly owned subsidiary, Lnet Corporation, which is engaged in the publication of information magazine and mail delivery business in Osaka, Japan, to SCINEX Corporation.Transaction amount is 270 mln yen in all.Effective date Oct. 1.After the transaction, the company will hold no stake in Lnet, down from 100 pct. Full Article
Wellco Holdings Corp:CS LOGINET INC said to acquire 90 pct stake in a new company founded by Lnet Corporation., which is a subsidiary of Wellco Holdings Corp on July 1, on May 14.Subsidiary cancels stake transfer to CS LOGINET. Full Article


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Indie Meme: Ship of Theseus
Not rated, 140 min. Directed by Anand Gandhi. Starring Aida Elkashef, Sohum Shah, Neeraj Kabi, Vinay Shukla and Sameer Khurana.
In this Indian film, three parallel stories are told about organ transplants and the ethical, personal, religious, and economic decisions behind each character's choice. Writer/director Anand Gandhi will be present for a Q&A following the screening.No current showings of this film.


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Grand Hotel Guayaquil
Select your stay dates to check availability at Grand Hotel Guayaquil
Grand Hotel Guayaquil
About the Hotel
Property Location
With a stay at Grand Hotel Guayaquil, you'll be centrally located in Guayaquil, steps from Simon Bolivar Statue and Guayaquil Metropolitan Cathedral. This hotel is within close proximity of Seminary Park and Parque Bolívar.
Make yourself at home in one of the 182 air-conditioned rooms featuring LCD televisions. Complimentary wireless Internet access keeps you connected, and cable programming is available for your entertainment. Private bathrooms with bathtubs or showers feature complimentary toiletries and hair dryers. Conveniences include phones, as well as safes and desks.
Treat yourself with massages and facials. You can take advantage of recreational amenities such as an outdoor pool, a sauna, and a fitness center. Additional amenities at this hotel include complimentary wireless Internet access, gift shops/newsstands, and wedding services.
Satisfy your appetite at the hotel's restaurant, which serves breakfast, lunch, and dinner. Dining is also available at a coffee shop/café, and 24-hour room service is provided. Quench your thirst with your favorite drink at a bar/lounge.
Business, Other Amenities
Featured amenities include complimentary high-speed (wired) Internet access, a business center, and complimentary newspapers in the lobby. Event facilities at this hotel consist of a conference center and meeting rooms. A roundtrip airport shuttle is complimentary during limited hours.
Hotel Facilities
- Business center
- Steam room
- Free breakfast
- Fitness facilities
- Wedding services
- Rooftop terrace
- Self parking (surcharge)
- Free WiFi
- Billiards or pool table
- In-room accessibility
- Meeting rooms
- Free wired high-speed Internet
- Free airport transportation - pickup
- Elevator/lift
- Television in common areas
- Designated smoking areas
- Gift shops or newsstand
- Accessible bathroom
- Multilingual staff
- Sauna
- Conference center
- Total number of rooms - 182
- Bar/lounge
- Pool sun loungers
- Spa services on site
- Porter/bellhop
- Free newspapers in lobby
- Safe-deposit box at front desk
- Outdoor pool
- Number of meeting rooms - 6
- Restaurant
- Laundry facilities
- 24-hour front desk
- Dry cleaning/laundry service
- Number of buildings/towers - 1
- Garden
- Coffee shop or café
- Number of floors - 6
- Luggage storage
Room Facilities
- Room service
- Hair dryer
- In-room safe
- Coffee/tea maker
- Blackout drapes/curtains
- Private bathroom
- Air conditioning
- Free bottled water
- Phone
- Desk
- Free toiletries
- Cable TV service
- Daily housekeeping
- Free cribs/infant beds
- Free WiFi
- In-room climate control (air conditioning)
- Bathtub or shower
- Free newspaper
Hotel Policy
Know Before You Go
- This property offers transfers from the airport. Guests must contact the property with arrival details 72 hours prior to arrival, using the contact information on the booking confirmation.
- Reservations are required for massage services and spa treatments. Reservations can be made by contacting the hotel prior to arrival, using the contact information on the booking confirmation.
- One child 2 years old or younger stays free when occupying the parent or guardian's room, using existing bedding.
- Some facilities may have restricted access. Guests can contact the property for details using the contact information on the booking confirmation.
- No pets and no service animals are allowed at this property.
The following fees and deposits are charged by the property at time of service, check-in, or check-out.
- Self parking fee: USD $5.00 per night
The above list may not be comprehensive. Fees and deposits may not include tax and are subject to change.
Mandatory Fees and Taxes
You'll be asked to pay the following charges at the property:
- A tax is imposed by the city: USD 1.50 per accommodation, per night
We have included all charges provided to us by the property. However, charges can vary, for example, based on length of stay or the room you book.Show all hotel policy Show less hotel policy


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For rent by Immanuel Lawrence Ltd VERIFIED 3 Feb 3:03 pmLekki, Lagos
Now available for lease is this Luxury 3 bedroom block of flats in Igbeafor, Lekki, Lagos state.
These apartments have space for outside parking space and security features.
For more information and tour guide, please call.
Stay safe!
Watch out for:


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Janet Arrowood is a long-time and frequent visitor to South east Asia. Huge lakes, tremendous waterfalls, elephant rides, jungles, wonderful people, fabulous food. The sense of the new and unknown will amaze you. Prices? Phenomenally low. And the scenery is spectacular. Canoe on Vietnam's historic lakes, kayak the South China Sea, see some of the largest waterfalls in the world, visit the islands, trek to hill-tribe areas, visit former royal palaces, wander through local markets. The imperial temples along the Perfume River are unforgettable. Laos and Cambodia, almost undiscovered by Westerners, are lands of stunning scene. "Adventure Guides" are about living more intensely, waking up to your surroundings and truly experiencing all that you encounter. Each book offers an ideal mix of practical travel info along with culturally enriching activities and physical adventures. And the fun is for everyone, no matter what his or her age or ability. Comprehensive background information - history, culture, geography and climate - gives you a solid knowledge of each destination and its people. Regional chapters take you on an introductory tour, with stops at museums, historic sites and local attractions. Places to stay and eat; transportation to, from and around your destination; practical concerns; tourism contacts - its all here! Detailed maps feature walking and driving tours. Then come the adventures - both cultural and physical - from canoeing and hiking to taking dance or cooking classes. This unique approach allows you to really immerse yourself in the local culture.
To view this DRM protected ebook on your desktop or laptop you will need to have Adobe Digital Editions installed. It is a free software. We also strongly recommend that you sign up for an AdobeID at the Adobe website. For more details please see FAQ 1&2. To view this ebook on an iPhone, iPad or Android mobile device you will need the Adobe Digital Editions app, or BlueFire Reader or Txtr app. These are free, too. For more details see this article.
Preview Ebook
If you find anything wrong with this product listing, perhaps the description is wrong, the author is incorrect, or it is listed in the wrong category, then please contact us. We will promptly address your feedback.


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Click on the "Convert & Download Video + MP3" button to start the video conversion. After the video conversion is finished, you can download the converted video in the formats MP4 or 3GP (for mobile phones) or you can download the converted audio as a MP3 music file. This online service is completely for free.
Bubbling Minds favorite! This superb track was taken from their first album, which was originally released in Peru on the Sono Radio label, and it was also c...
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Gianfranco Dettori
Gianfranco Dettori (born 25 April 1941) is an Italian retired Thoroughbred horse racing jockey.
Dettori was born in Serramanna, in what is now the Medio Campidano, Sardinia. During his career, he won an Italian riding championship thirteen times. In addition to winning many major races in Italy, Dettori won in Great Britain as well, capturing such races as the Classic 2,000 Guineas in 1975 and 1976, plus the Benson & Hedges Gold Cup and Eclipse Stakes in 1976.
He is the father of jockey Frankie Dettori.
- Profile of Gianfranco Dettori at the Serramanna commune website (Italian language)
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The kids from the 90's Sunny D commercial are all grown up
Description:If you've wondered what happened to the rollerblading kids in the old, iconic SunnyD spot from the early 90's, wonder no more. They're still at it. And Mrs. B is pretty much over it. #KeepItSunnyPeople
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|Click here to view the item
|Baldowski, Clifford H., 1917-
|--Whoa!-- Y'wild, cussed, onery critter!-- Whoa!-- / Baldy, [ca. 1967].
The Clifford "Baldy" Baldowski cartoon depicts Howard "Bo" Callaway labeled "Callaway Amendment," and Garland Byrd, labeled "Byrd Suit." They are flogging a dead horse, labeled "racial balance" as a laughing white horse labeled "real law" watches.
|Editorial cartoons | Visual works
|Callaway, Howard H. (Howard Hollis), 1927- | Byrd, Garland T. (Garland Turk), 1924-1997 | Georgia--Race relations | Georgia
|Baldy Editorial Cartoons, 1946-1982, 1997: Clifford H. Baldowski Editorial Cartoons at the Richard B. Russell Library.
|Digital Library of Georgia
|Clifford H. Baldowski Editorial Cartoon Collection (Digital Library of Georgia) | Digital Library of Georgia | Richard B. Russell Library for Political Research and Studies
|Online Publisher:
|[Athens, Ga. : Digital Library of Georgia] | 2001
|Original Material:
1 item ; 32 x 40 cm. paper pen and ink. [Atlanta, Ga. : Atlanta Constitution, ca. 1967]
|Rights and Usage:
The Baldowski cartoons created for The Atlanta Journal-Constitution are licensed to the Richard B. Russell Library for Political Research and Studies, University of Georgia Libraries by The Atlanta Journal-Constitution.
Contact repository re: reproduction and usage.
Cite as: [Title of the cartoon], [Date of cartoon], editorial cartoon by Clifford H. Baldowski, Clifford H. Baldowski Editorial Cartoon Collection, Richard B. Russell Library for Political Research and Studies, University of Georgia Libraries, Athens, presented in the Digital Library of Georgia.
|Related Materials:
Forms part of the Clifford H. Baldowski Editorial Cartoon Collection.
|Persistent Link to Item:


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- Magazine
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UCB and Amgen submit FDA application for Osteoporosis drug
22 July 2016 • Author: Niamh Louise Marriott, Digital Content Producer
UCB and Amgen today announced the submission of a Biologics License Application (BLA) to the U.S. Food and Drug Administration (FDA) for romosozumab, an investigational, monoclonal antibody for the treatment of osteoporosis in postmenopausal women at increased risk of fracture.
Romosozumab works by binding and inhibiting sclerostin, a protein naturally occurring in the bone, thereby increasing bone formation and decreasing bone resorption.
"Osteoporosis is a chronic disease, largely asymptomatic, and often undetected until a fragility fracture occurs. Many patients view fragility fractures as part of aging but these fractures are an indication of a weakened skeleton and a signal for intervention with medication," said Dr Pascale Richetta, Head of Bone and Executive Vice President at UCB.
"We are pleased to submit the first regulatory submission for romosozumab, and are committed to seeking global regulatory approvals in the hopes of making this important therapy available for appropriate patients at increased risk of fracture."
The BLA for romosozumab is based on data from the pivotal Phase 3 placebo-controlled fracture study in post-menopausal women with osteoporosis, approximately 7,200 patients. UCB and Amgen plan to present results from the clinical trial at an upcoming medical congress.
"Osteoporosis is a large public health problem yet is often overlooked, even in patients who have already experienced an osteoporotic fracture," said Sean E. Harper, M.D., Executive VP of Research and Development at Amgen. "This BLA submission is an exciting milestone; romosozumab has the potential to reduce the risk of fractures and help patients suffering from this serious disease."
Osteoporosis-related fragility fractures are common. In the United States, one in two women over the age of 50 will experience an osteoporotic fracture yet data shows that only about 20 percent of women who have experienced a fracture receive any type of osteoporosis treatment during the first year post fracture.


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Where to Find Maple Lumber in North Carolina?
Three species of maple are native to North Carolina. The wood from these trees has a variety of uses from construction to the fabrication of fine furniture, bowling pins, baseball bats, pool cues a...
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Where can you find a adolescent psychiatrist in western North Carolina?
I just did a google search for "adolescent psychiatrist" nc and found this webiste: revolutionhealth. This let me search for a specialist in adolescent psychiatry within "x" miles of a city/state ...
Read More »
Where Can I Find Longleaf Pine Trees in North Carolina?
Named for its foot-long needles, the longleaf pine is the state tree of North Carolina. Once logged to near extinction, the longleaf pine's recovery is hampered by a diminishing habitat. In North C...
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Where do i find divorce papers that were filed in Charlotte, North Carolina?
To obtain a copy of divorce papers, contact the Mecklenburg Court Clerk at (704) 686-0430. Copies can also be obtained online at the North Carolina Public Health website by completing a certificate...
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How many miles to travel from Bryson City, North Carolina, to Fayetteville, North Carolina?
Via road, the distance between Bryson City and Fayetteville, North Carolina, is roughly 325 miles. The trip, which travels west through such cities as Greensboro, Hickory and Asheville, takes rough...
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|» Step 1: Tell Us About Your Case
|» Step 2: Provide Contact Information & Submit
Start a Lawyer Search
Tell us about your case so that we can connect you with the right lawyers.
Vasilaros Wagner
We practice only personal injury law and represent all types of accident cases.
Address: 721 Beville Road - South Daytona, FL 32119
Phone: (386) 777-7777
Rue & Ziffra
Address: 632 Dunlawton Avenue - Port Orange, FL 32127
Phone: (386) 788-7700
Kaufman & Lynd, PLLC
While our firm focuses on Personal Injury, we have years of experience providing legal services to individuals and companies in many areas of law. We provide these other services because of the comfort level and confidence our clients have in us.
Address: 200 E Robinson St Suite 250 - Orlando, FL 32801
Phone: (407) 706-3535
Gregory Nordt and Associates
Helping the Injured throughout the State of Florida for Over 22yrs. Call For Free Consultation. No Fee Unless we are Successful.
Address: 5900 SW 13th Street - Plantation, FL 33317
Phone: (954) 325-8475


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Gap Year Opportunities in the UK
Are you looking for a gap year in the UK where you can make a difference whilst gaining valuable skills and experience? If so, then a Full Time Volunteering placement with Volunteering Matters could be for you!
We are offering the unique opportunity for people aged 18-35 to undertake the challenge of living away from home for 6-12 months while volunteering at one of a wide range of projects helping and supporting people and communities across the UK.
You could be volunteering with people with physical disabilities, learning disabilities or mental health issues, older people, homeless people, families, children or young people. We work with a range of partners include schools, universities, social services departments, homeless hostels and other charities.
You could be carrying out a wide range of activities including:
- Befriending and supporting
- Acting as a mentor
- Enabling access to social and leisure activities
- Helping with personal care
- Assisting with practical tasks such as shopping or cooking
Our volunteers receive:
- Free accommodation
- Subsistence to cover food and day to day expenses
- Travel expenses to and from your project
- Return travel home every four months
- Support and relevant training
- Certificate and reference
You would need to be:
- Able to volunteer for 6-12 months for 35-40 hours per week
- Aged 18-35
- Able to move away from home and volunteer anywhere in the UK
- Willing to be matched to a p[roject where your help is needed most
- Able to provide two suitable references
Applicants must be a UK, EU, EEA national and applying from the UK
Interested in this; ready to enquire?
Find out more by filling out the form below and clicking send. Volunteering Matters should then be in touch shortly to help with your enquiry.