text:
Angela Ahrendts: the woman aiming to make Apple a luxury brand
Marlene Breverman stashed this in Tech/Business
"Confirmed last week as the tech giant's highest-paid executive, the ex Burberry chief is charged with making the Apple 'experience' even sleeker. It might also mean larger"
Stashed in: Women, Apple, Awesome, Extraordinary People, Women, Women in Tech, Women
"There's something of the cult leader about her. She never let you see a moment of doubt or even questioning"
Stacy, good one. I like this one:
I thought it already was a luxury brand but I suppose that just shows how much of a pleb I am.
Charlotte wrote:
Not sure if I agree with this quote "If you can't control everything, you can't control anything."
I don't agree with that quote, too.
We can certainly control SOMETHING. Just not everything.
"I don't buy apple products for their "lifestyle" I buy them because they work with a lot less problems than a PC. I wonder if she really knows apples users as well as she knows the companies history."
I guess we're going to find out. As far as I know Apple products work as well as they ever did.


text:
Mobile App
SP Meerut
Shanti Polytechnic
Uttar Pradesh
Total Students
Fees Range
How to reach
Shanti Polytechnic is situated at Bagpat Road, Kurali, Meerut, Uttar Pradesh 250501 in Meerut.
Courses Offered
- 3 Years
- Diploma
- Engineering
- 3 Years
- Diploma
- Engineering
- 3 Years
- Diploma
- Engineering
- 3 Years
- Diploma
- Engineering
Shanti Polytechnic - SP Meerut - SP
Shanti Polytechnic All India Council of Technical Education (AICTE). The vision of Shanti Polytechnic is to be the leading centre of learning and innovation in emerging areas of business and management education. For every course the college imparts practical training to its students that helps them to understand better, improve their demonstrative skills, eliminate hesitation and in this process strives to mould them into industry ready professionals. Mission of Shanti Polytechnic is 'to foster critical analysis by training students both in theory and practice so as to equip them with skills needed for facing global challenges with team work and human values. And to build quality network with the Industry, educationists and the society for exchanging knowledge'. The modern teaching methodology assists the students in getting an all around view of engineering, technology and the entrepreneur world. The diligent faculty team of the college possesses hands-on experience and up to date knowledge of their subject and area of expertise. The infrastructure and facilities of Shanti Polytechnic consists of spread-out campus alongside various amenities in the form of library, computer center, classrooms with proper teaching and learning aids, medical facilities etc. The institute seeks to place each of its students in an organization/company of great repute.
Why join Shanti Polytechnic Meerut
The college has well state of the art infrastructure facilities.
4 Type Courses Available
- 4 Diploma Courses
Shanti Polytechnic Placements
Visiting Companies
Student Placement
At Shanti Polytechnic (SP) the students are endowed with all convenient amenities that make their life 'go easy' in college hours, alongside make learning more interesting. Some of the facilities include well ventilated classrooms, recreational areas, hostel facility for boys and girls, indoor and outdoor games, stocked library, seamless internet/wifi connectivity, medical facilities etc.
Try our extensive database of FAQs or submit your own question...
JEE Advanced 2017: Candidates from Lucknow, Indore & Varanasi Skip Examination 24-May-2017, 05:57 PM
Should I do integrated MCA or 4 year CS Prateek Shrivastava Asked this 1 year, 11 months ago - India
Should I do engineering or sciences? Harsh Vvvv Asked this 1 year, 11 months ago - India
placement MAYANK GUPTA Asked this 1 year, 11 months ago in Veterinary Science - India

subset: commoncrawl


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Company Description: FREY Building Contractors - Home
Industries: Architecture And Planning, Building Contractors
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Spatially Registered Multispectral Polarimetric Sensor
Award Information
Small Business Information
27-2 Wright Road, Hollis, NH, 03049
Principal Investigator
Name: Richard Nelson
Title: Vice President of Spectral Sensors
Phone: (603) 598-1194
Email: email@example.com
Title: Vice President of Spectral Sensors
Phone: (603) 598-1194
Email: email@example.com
Business Contact
Name: Linda Bouthillette
Title: Contract Administrator
Phone: (603) 598-1194
Email: firstname.lastname@example.com
Title: Contract Administrator
Phone: (603) 598-1194
Email: email@example.com
Research Institution
AbstractSolid State Scientific Corporation (SSSC) is pleased to propose the design and modeling of a unique Multi-Spectral Polarimetric (MSP) imaging sensor that will be capable of simultaneously imaging seven color bands and two polarimetric images. The approach will utilize recent developments in micro-optics to create a 9-channel multi-spectral imager based on a single focal plane array. The resulting MSP imager (MSPI) will operate in the visible/NIR band, incorporate a 3x3 array of micro-lenses, and use a 1000x1000 staring imager to capture seven 333x33 spectral images and two 333x333 polarimetric images during each integration time. The new sensor will have no moving parts, occupy a small physical form factor, and run on a laptop computer. The design and development of this sensor represents a unique opportunity in hyperspectral and polarimetric sensing and imaging. This effort will benefit the development of algorithms for exploiting hyperspectral and polarized image processing techniques for static scenes and temporally evolving spectro-polarized events. This MSPI will sample the object scene at rates up to 48 spectro-polarimetric images per second with minimal computational requirements. The sensor concept is scalable to larger or smaller imaging formats, and the spectral resolution for both spectral and polarimetric images can be adjusted to increase the spatial sampling for specific applications. In addition, the sensor can be configured so that the spectral resolution varies independently of the sampling, allowing the sensitivity of the sensor to be optimized around phenomenologically important spectral regions.
* information listed above is at the time of submission.
An Official Website of the United States Government


text:
With Instructables you can share what you make with the world, and tap into an ever-growing community of creative experts.
Tell us about yourself!
DIY Screen Printing: Easy, Detailed & Inexpensive!
D.I.Y. Screen Printing
Jar Lantern
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Polishing Silver the Easy Way - With SCIENCE!
The Fox Hole, a Hooded Winter Baby Sling
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Leather Cuff Watch Band + Leather Bracelets 101 - Be Fashionable No Matter What Time You Arrive!!
Eye mask + pattern
4 Easy Steps to Creating a Unique Wine Bottle Lamp
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How to make a leather phone case.
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|Message view
|« Date » · « Thread »
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|"Jason van Zyl (JIRA)" <j...@codehaus.org>
|[jira] Closed: (CONTINUUM-159) results not shown in building state, even if there were previous results
|Tue, 05 Jul 2005 03:37:15 GMT
[ http://jira.codehaus.org/browse/CONTINUUM-159?page=all ] Jason van Zyl closed CONTINUUM-159: ----------------------------------- Resolution: Fixed Result will be show for projects in all states except the new state. We don't want to actually look at the builds on the summary page because that would require JDO to detach the builds collection and for the summary page that would be very expensive. > results not shown in building state, even if there were previous results > ------------------------------------------------------------------------ > > Key: CONTINUUM-159 > URL: http://jira.codehaus.org/browse/CONTINUUM-159 > Project: Continuum > Type: Improvement > Components: continuum-web > Reporter: Brett Porter > Fix For: 1.0-alpha-3 > > > the test for allowing linking to results should just be if there are >0 -- This message is automatically generated by JIRA. - If you think it was sent incorrectly contact one of the administrators: http://jira.codehaus.org/secure/Administrators.jspa - For more information on JIRA, see: http://www.atlassian.com/software/jira
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Hi guys and girls,
being a recnet convert to BMW's I am in a postion whereby i need to have the rear pads and discs changed on my E92 335 Coupe. I have been quoted £400 for it which i feel is quite steep, although it was using genuine parts.
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amr better than wav lc INSTRUCTIONS:
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Click Add Files to load WAV audio files for WAV audio AMR conversion
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2'6" x 6'3" / 75cm x 190cm
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This 3'0 Snuggle Miranda bedframe is an ex-display model from one of our stores.This item may have some marks from shop use.This is why it is available at this cheaper price. Make sure you grab a bargain today! Please note that this frame has been laid on but not slept on!!
This is the Miranda from Snuggle Beds. Timeless bunched swirls grace the head and foot end. With a sturdy build quality, sprung slats and a centre support rail, the Miranda is sure to be an elegant centrepiece to your bedroom for years to come. Safety conscious snuggle have used plastic tops on each leg.
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text:
Funeral to be held in Quebec today for RCMP constable killed in tractor collision
SAINT-JEAN-SUR-RICHELIEU, Que. — A funeral will be held in Quebec today for an RCMP officer who died after a crash between his vehicle and a farm tractor.
CHETWYND, B.C. — The RCMP are investigating the deaths of three people in the remote northeastern B.C. community of Moberly Lake.
Investigators say Mounties from the Chetwynd detachment discovered the bodies in a home in the Lakeview subdivision after responding to a report of a disturbance Friday morning.
No names or other details concerning the deceased have been made public.
An RCMP release says members of the force's Victims Assistance Service have been at the scene helping those affected by the incident.
It also says that police do not believe there is any further risk to the public.
The RCMP North District Major Crimes Unit is investigating the deaths in co-ordination with the B.C. Coroner Service.
The Canadian Press


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text:
14 May 2017; Happy Mother's Day and Dixie Trek
Happy Mother's Day! Noel Neill – the Original Lois Lane – portrayed little Lois Lane's mother in Superman-The Movie. Noel is uncredited in the movie, but is credited on IMDB as Ella Lane for her role.
Today is the 23rd anniversary of Noel Neill and Christopher Reeve's appearance together at the Atlanta Dixie Trek Convention. I was there and covered the entire affair. Click here to visit our Dixie Trek page.
09 April 2017; The 1979 Oscars & Other Awards
38 Years Ago Today, April 9, 1979: Superman-The Movie wins at the Oscars! Click here for the whole story, plus other awards the movie received.
28 March 2017: Superman Production 40th & CapedWonder.com 15th
First Day of filming during the Richard Donner Superman Years (1977-1978): Despite a nagging head cold, Marlon Brando arrives at Shepperton Studios that morning to begin filming his first scenes as Jor-El for the two 'Superman' films under the direction of Richard Donner. Brando is draped in black velvet and filmed teaching Kal-El via an education crystal. Christopher Reeve is on set to watch Brando at work. Brando later informs Creative Consultant Tom Mankiewicz that day that he has just read the complete script and calls it a "valentine". Featuring an unreleased head-shot of Marlon Brando. Source photo from Jay Towers. Restoration by Jim Bowers.
CapedWonder.com is 15 Years Young! Thanks to the Incredible Superman Cast & Crew and Super Fans like You!
24 March 2017: Krypton Gallery Updates
I've updated the Krypton gallery with lots of new photos. Below are a few. Check them all out here!
23 February 2017: Christopher Reeve Revealed to the World
"He'll portray the caped wonder from Krypton…" Christopher Reeve was announced 40 years ago today as the new Superman and Clark Kent at a press conference at Sardi's Restaurant in New York City.
17 February 2017: Pa Teaches Clark at the Farm
Richard Donner and his Superman team planned to include in 'Superman-The Movie' a photo stills montage showing Clark Kent's time growing up on the Kent farm, much like was done for Donner's, The Omen, in 1976. See the photo stills montage from The Omen here. As a side note, you can see Holly Palance in the scene after the stills montage in The Omen; she was Lois Lane during Christopher Reeve's Superman screen test on February 1, 1977.
Ultimately, Superman set photographer Bob Penn *did* shoot photos for a montage (using five little Clark Kent actors, including Aaron Smolinski and his older brother, Travis), but those photos were never included in any edit of the movie that I am aware of (work print, etc.), or used in publicity.
Below is one of Bob Penn's photos for the stills montage, featuring Travis Smolinski and Glenn Ford at a chalkboard in the backyard of the Kent farm house, filmed in Canada in August 1977.
Here's an excerpt from David Michael Petrou's amazing book, The Making of Superman-The Movie:
"[Publicist] Gordon Arnell and [set photographer] Bob Penn, along with special-effects man John Richardson, were on the Kent farm set most of that first week, coordinating an elaborate still-shot sequence which might possibly be incorporated into the film, detailing the growth and displaying the super powers of young Clark. Using the young boys selected at the earlier casting session in Calgary, Richardson had to create effects which included milking a cow at super-speed, chopping a cord of wood in a single blow, and lifting a tractor. Since these fantastic actions had to be depicted in still shots rather than in motion, the sequence provided Bob Penn with some unique problems."
16 February 2017: Pa Meets Clark at the Farm
Please enjoy this unreleased photo of Glenn Ford and Jeff East as Jonathan and Clark Kent on the farm, filmed in Canada in 1977. I'm updating the Smallville gallery, as well as many other Superman-The Movie galleries. Please check back often.
06 February 2017: Queen Elizabeth II Cup
Queen Elizabeth II commemorated her 65th anniversary as queen today. Take a look at Richard Donner's cup in the photo below; it's from Queen Elizabeth II's 25th anniversary (1977). You can buy one of these vintage cups on Etsy (I own one).
01 February 2017: Superman's Screen Test
Christopher Reeve's Superman screen test took place 40 years ago on February 1, 1977. Holly Palance, daughter of actor Jack Palance, played Lois Lane. She starred in Richard Donner's 1976 film, The Omen. She retired from acting in 1989.
This is a photo of Chris during his Superman screen test shot by an unknown photographer using a "Pocket Instamatic" 110 camera. "Pocket Instamatic" 110 cameras were very popular as a low-cost film option for general consumers, starting in 1972. A 110 film cartridge contains negative film that is a mere 0.51″ × 0.67″ in size, and, thus, produces so-so quality prints as compared to 35mm. I own many other 110 negatives from the production of Richard Donner's Superman movies; here's a scan of one (shot by an unknown photographer from the kitchen of the Kent farm in Canada).
24 January 2017: The Dreams Poster
We made a few updates to one of Ramon Casares' fabulous 2004 "Dreams" inspirational posters.
19 January 2017: The Kent Farm
The farm used for the Smallville scenes in Superman-The Movie is a real farm that turns 100 years old this year.
According to Bill Brodie's scouting records (now part of the CapedWonder Collection), the farm owner intended to tear down the house and barn after production wrapped in August 1977, but, for unknown reasons it never happened, and the structures stand to this day.
The farm has a different owner today. Over the past seven years, I've had many enlightening phone calls and e-mail correspondence with the owner's spokesperson; they seem to be decent people who are very private.
The owner does not permit anyone on the property. There has apparently been much vandalism, and at least one break-in, which has greatly upset the owner.
I strongly recommend staying away from the farm. The owner's spokesperson has already issued multiple cease-and-desists to people who have entered the property, and has threatened to get the police involved, with the intention of charging offenders with possible unlawful entry/breaking & entering, trespassing, and/or theft. They are very serious about this matter.
The owner and their spokesperson are well aware that I have photographed the property, but we have a written agreement that I will not post my photos anywhere on the World Wide Web and not divulge the farm's location.
If you have been to the farm and have posted your photos on-line, I urge you to take them down. If you do happen to drive by the farm and take photos from the public road sitting in your car, do yourself a favor and don't post those photos on-line. You'll be glad you made that decision.
18 January 2017: Gallery Updates Continue
I am still updating the Superman-The Movie galleries, so check them out here!
13 January 2017: Superman-The Movie Gallery Updates
The majority of the Superman-The Movie galleries have been updated with new and improved photos; check them out here.
There is still more work to be done in the Marketing & Promotion and Premieres/Press Junkets galleries; I am updating those during the first and second quarter of this year.
Below is a scan of an original storyboard from the CapedWonder Collection; see more storyboards here.
12 January 2017: The Super Train
Featured below is a photo of Clark Kent jumping in front of the Kansas Star train in Superman-The Movie (top) and an original photograph shot by me at the exact same level crossing – an intersection where a railway line crosses a road or path at the same level – in Canada in 2011 (bottom). I was fortunate to have a train go by while I was there, as it was a very quiet track that day.
11 January 2017: Lynn Stalmaster Believes in Christopher Reeve
40 years ago this month – January 1977: Casting director Lynn Stalmaster strategically places a casting photo of a young stage actor on the top of Richard Donner's inbox, only to discover later that the photo is placed at the bottom of the pile. Undeterred by his thoughts on the young actor, Stalmaster again places the photo at the top of the inbox, and again, three times in total. Donner takes a shot and contacts the actor, who is in the middle of production on the play, My Life, as an understudy for William Hurt, via his agent, to come in for a reading. The agent informs the actor that the chances of getting the part are remote at best because no one had seen a script. Christopher Reeve agrees to meet with Richard Donner to discuss the Superman project.
Read about Lynn Stalmaster's amazing career here. And see his acceptance speech below for his Honorary Oscar at the 2016 Governor's Awards in the Ray Dolby Ballroom at Hollywood & Highland in Hollywood, CA, Saturday, on November 12, 2016.
These photos of Christopher Reeve below, shot to promote his character on the TV soap opera, 'Love of Life', were taken within a couple of years of Christopher Reeve first meeting Richard Donner about Superman. The headshot – with the white background – was scanned and retouched by me, and can be seen all over the internet on various websites, blogs and social media outlets.
09 January 2017: Superman II Alley Transformation
Please enjoy this panoramic of Clark Kent's transformation into Superman in the back alley from Superman II using numerous Blu-ray screenshots. Click on the image and it will open in its own box. Then save the PNG file to your computer and open it with your favorite viewer to enjoy the full-size version (3447 x 400 pixels).
07 January 2017: Superman-The Movie Screenshots
Many Superman-The Movie screenshots have been uploaded to our satellite website on SmugMug. Please enjoy them here. There even more screenshots at the top of this page; see the far right dropdown.
01 January 2017: Wishing You a Prosperous New Year!
Hand-craved "CapedWonder Superman Imagery" by Michael J. Stribling. The carving is laying on a Giclée canvas gallery wrap enlargement of a Curt Gunther photo of Christopher Reeve as Superman. Photography and layout by Jim Bowers.


text:
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text:
Location: Cereal Crops Research2011 Annual Report
1a. Objectives (from AD-416)
The objectives of this cooperative research project are: 1) identify tan spot and Stagonospora nodorum blotch resistance genes in wheat, 2) determine the chromosomal locations of the resistance genes, and 3) identify or develop markers suitable for marker-assisted selection of the resistance genes.
1b. Approach (from AD-416)
A recombinant inbred (RI) population derived from a cross between the resistant wheat landrace Salamouni and the susceptible Canadian variety Katepwa will be developed for the identification and mapping of novel resistance genes. The RI population will be genotyped with molecular markers, and linkage maps representing all 21 wheat chromosomes will be assembled. The population of RI lines will be screened for reaction to multiple races of the tan spot fungus and isolates of S. nodorum. The phenotypic data will be regressed on the molecular marker data to identify quantitative trait loci (QTL) associated with resistance. Genomic regions harboring significant QTL will be targeted for saturation mapping to identify and/or develop user-friendly PCR-based markers tightly linked to the QTL for marker-assisted selection.
3. Progress Report
The RI population derived from the parental wheat lines Salamouni and Katepwa was completed, and seed of each of the 121 RI lines was increased. Each line of the population was evaluated for reaction to ToxB, which is a toxin produced by the fungus that causes the disease tan spot. By evaluating each line and determining if they were sensitive or insensitive to ToxB, we were able to determine the chromosomal location of the Tsc2 gene, which is the gene that governs sensitivity to ToxB. The Tsc2 gene mapped to the short arm of wheat chromosome 2B. Next, we identified molecular markers that mapped near the Tsc2 gene, and we developed new markers based on previously determined DNA sequences of genes on chromosome 2B, to saturate the region of the genetic map containing the Tsc2 gene. This allowed us to make detailed comparisons of the wheat chromosomal region containing the Tsc2 gene with syntenic regions of the rice and Brachypodium genomes, which then allowed us to develop more markers that were more tightly linked to the Tsc2 gene. We showed that one marker very tightly linked to Tsc2 will be useful as a tool for marker-assisted selection against the Tsc2 gene, which would result in higher levels of tan spot resistance. ADODR monitoring included personal visitation, email correspondence, and telephone discussions.
4. Accomplishments


text:
Miranda Kerr leaving a yoga class in L.A. (4/3)
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text:
The government's Consumer Price Index (CPI) rose slightly in August as steady food and energy costs mitigated increases in rising shelter and health care prices.
The Bureau of Labor Statistics (BLS) reports the CPI was up a scant 0.2% last month, with prices over the last 12 months gaining 1.1%
Food costs hold steady
As it was a month earlier, the cost of food was unchanged in August, with food at home -- grocery store prices -- falling 0.2%. Meats, poultry, fish, and eggs were down 0.4%, the 12th decline in a row. The "other food at home" category fell 0.2%, and prices for nonalcoholic beverages dipped 0.1%. The remaining major grocery store prices were all unchanged in August.
During the past 12 months, food prices overall were unchanged -- the first time that's happened since the 12 months ending February 2010. Grocery store prices were down 1.9% over the past 12 months.
Energy costs unchanged
The price of energy held steady after declining in July, with gasoline and fuel oil down 0.9% and 2.5%, respectively. Natural gas, on the other hand, was up 2.1% after surging 3.1% in July. Electricity rose 0.5%, the same increase as in July.
Energy prices have declined 9.2%, with gasoline down a whopping 17.8% and fuel oil dropping 12.8%.
Core inflation
The costs of living excluding the volatile food and energy categories -- what's known as the "core" rate of inflation -- was up 0.3% in August, led by medical care (+1.0%) and shelter (+0.3%). Other increases came in prices for motor vehicle insurance (+0.5%), apparel (+0.2%), and tobacco (+0.7%).
Declining prices were seen for used cars and trucks (-0.6%), as well as household furnishings and operations, recreation, and airline fares (all -0.1%).
The core rate of inflation over the past 12 months was up 2.3%, led by motor vehicle insurance (+6.5%), medical care (4.9%), and shelter (+3.4%).
The full report may be found on the BLS website.


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Eddy Wood
Eddy Wood
Chief Wood has been with the City of North Richland Hills since October 12, 1998 and is currently assigned to the Operations Division as a Shift Commander. He is a certified Paramedic and holds the following Texas Commission on Fire Protection certifications:
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Chief Wood is a graduate of the Texas Fire Chiefs Academy. He has been the Tarrant County TIFMAS Coordinator since 2014. Chief Wood was Officer of the Year in 2012 and firefighter of the year in 2005. He also received the Medical Director's Award in 2009.
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Great Mall
- Where
- 447 Great Mall Dr, Milpitas , CA
- Call
- 408 9562033
- Web
- Great Mall Website
- Tags
- Shopping, Consumer Electronics, Shopping Centers
|Claim this listing
Free Valet Parking
This Silicon Valley shopping center is the largest outlet mall in Northern California with more than 185 notable stores, 6,300 parking spaces, and a variety of amenities ranging from a 700-seat food court and ATMs to strollers and guest services. Located 50 miles south of San Francisco, residents throughout the Bay Area flock here to save up to 70 percent on brand name apparel, shoes, jewelry and accessories, home furnishings, toys, sporting goods, electronics, eyewear, and gifts.
More Silicon Valley Shopping
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Visit Milpitas.com for Hotels
Great Mall@ShopGreatMall
- RT @MommyPowers: Have you heard?! @ShopGreatMall will be OPEN on #MemorialDay 10am-9pm, for your shopping pleasure! #FoundAtSimon #ad https…
- For the perfect snack, stop by @AuntieAnnes. https://t.co/3vvcAwhXEe
- Summer vibes. #Levis https://t.co/ty4sOuiwpT


text:
Barrington Stagemasters performing Clue
Think you know "Who done it?" Think again.
The Barrington High School Stagemasters will perform CLUE on Thursday, Saturday and Sunday, and will present a different ending at each performance.
Theater teacher Stephanie Spaziano said the show will also include audience participation, "and just like the board game, audience members will be able to make accusations."
The two-act play is based on the Parker Brothers classic board game and is being produced with special permission from Hasbro, Inc.
The performances will feature the six original Clue characters — Miss Scarlet, Col. Mustard, Mr. Green, Mrs. White and Mrs. Peacock — as well as characters from Clue Master Detective, Cluedo (the UK version of the game) and Cluedo Super Sleuth.
This will be the Stagemasters' final production of the 2013-14 school year. Tickets are $5 for students and $8 for adults.
• Thursday, April 10, at 7 p.m.
• Saturday matinee, April 12, at 2 p.m.
• Saturday, April 12, at 7 p.m.
• Sunday matinee, April 13, at 2 p.m.


text:
Rangeley Travel Guide
Photos from RangeleyPictures of Rangeley (81)
Hotel Deals in Rangeley
Travel Blogs from RangeleyRangeley Travel Blogs (11)
From Canada to the States
... drove inland to Rangeley in our continuing search for Moose. Now if I thought Bar Harbour was gorgeous this certainly tops it. Rangeley is surrounded by a number of lakes and forestry. The leaves are just starting to change their colours and we can see ...
Day 118: Andover, ME to sabbath day pond
Howdy! Nice to wake up dry and sleeping on sheets at the Pine Ellis Hostel. About 30 minutes later the downpour starts. Raining so hard that I got soaked just running from the bunkhouse to the main house. I was going to take a shuttle with some ...
Change of State
Days 24, 25 and 26: His take on Our Rangeley stay: We had a relatively short drive through very agreeable Autumn foliage into the State of Maine. Our stay is in Rangeley, on the 45th parallel exactly half way between the Equator and the North ...
Our Camp in Maine
... a few days it feels normal. We stayed at camp for three weeks so we went a long time without electricity. Every week we would go to Rangeley to stock up on food and use the wifi at a cafe. It was nice to have some time to catch up on things. One of the ...
Attractions in RangeleyRangeley Attractions (8)
Saddleback Mountain
Rangeley, Maine, United States
Coos Canyon
Route 17 Rangeley, Maine, United States
Kennebago Lake
Rangeley, Maine, United States
Rangeley Lakes Region Logging Museum
Box 154, Rangeley, Maine, United States


text:
The 31-year-old South Africa batsman hit 135 not out to help his side bounce back from 39 for three as they attempted to overhaul a first-innings deficit of 178.
Championship debutant Luke Fletcher took two out of the three wickets to fall in the day, trapping both Tom Smith and Francois du Plessis lbw.
Paul Horton was caught behind by stand-in wicketkeeper Bilal Shafayat off the bowling of Ryan Sidebottom.
But Prince shared an unbroken fourth-wicket partnership of 191 with Mark Chilton (56 not out) to help his side to 230 for three declared. Both sides agreed to shake hands just before 5pm.
Michael Carberry and James Adams scored half-centuries as Hampshire's LV County Championship match with Sussex petered out into a dull draw at the Rose Bowl.
Sussex, 120 behind overnight in their first innings, chose to bat on until they were all out in a bid for batting bonus points.
Hampshire took a 14-run lead into their second innings but had no option but to bat through the last two sessions to render the last day of a rain-hit match meaningless.
Sussex resumed on 230 for six in reply to Hampshire's first-innings total of 350 for eight declared and went on to make 336, with wicketkeeper Matt Prior scoring 140.
Damien Wright (42) and Ragheb Aga (24) put on 55 for the ninth wicket. Carberry then scored 72 and Adams an unbeaten 55 as Hampshire closed on 127 for two.
- More about:
- Bowling
- Cricket
- Hampshire
- South Africa
- South East England


text:
DLA Piper has announced that Geoffrey M Ossias has joined the firm's corporate and finance practice as a partner in the Phoenix office.
Ossias focuses his practice on emerging companies in a range of technology-driven sectors, including healthcare, e-commerce, renewable energy and financial services.
He regularly assists these companies in a variety of strategic transactions, including debt and equity offerings, mergers and acquisitions and the resolution of complex corporate governance matters.
He also regularly represents venture capital and private equity funds in connection with their investments in early-stage companies. Earlier in his career, Ossias was a co-founder of MyPoints.com, a publicly traded internet marketing firm in San Francisco.
Ossias is the most recent addition to the firm's growing Phoenix office, following the hiring of Kevin Lytle and Craig Cartwright in the office's real-estate practice in June.
He joins DLA Piper from Quarles & Brady, where he was co-chair of the firm's emerging growth companies practice.


text:
|Reviews for Paint the Town Red
| sunflowerspot chapter 1 . 3/13/2013
I love this! So glad to see they got their happy (and much, much more fun) ending. I really wish we'd seen more of him in the show, but at least there's always fan fiction. Great oneshot! :)
| RedGusFan chapter 1 . 12/30/2012
Yea! They finally did something!
| Moma bear Emma Swan chapter 1 . 12/7/2012
I wanted them to be a bpule :{
| Searching For Wonderland chapter 1 . 10/12/2012
This was cute, and a little saucy which of course isn't a problem. Great job :-)!


text:
ED Magedson – Founder
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Occasionally, The Insider samples what folks outside The Post are writing about the team.
The D.C. Sports Bog, Insider and Fancy Stats took a spin this morning through the idea that Robert Griffin III isn't one of the NFL's 100 best players. Elsewhere, here's what folks were writing about:
● Earlier this month, Rivers McCown of Football Outsiders took a closer look at how Jordan Reed performed, finding that he created mismatches in the middle of the field. He also looked at where most of his catches took place, and how he performed on screens.
After last week's minicamp, offensive coordinator Sean McVay talked about what a big key Reed is:
● ESPN's John Keim has used the slow season to revisit both the 2012 and 2013 draft classes. Here's his take on Adam Gettis, a guard taken in the fifth round in 2012, and someone discussed yesterday in the crowdsourcing thread:
Has a fight on his hands. LeRibeus' strong spring plus the drafting of Long means the Redskins might not have a spot for Gettis. Remember, too, that veteran Mike McGlynn can play guard and center. Gettis improved as a run blocker in space last summer and must continue to do so. He still has a tendency to get driven back, though still anchoring, in pass protection. The numbers might not add up for him.
● Pro Football Focus took a closer look at the Redskins' depth chart, determining that they were made up of 21.4 percent high-quality staters, 14.3% good and 25% average, among other things.
● The Redskins' Web site wrote a feature on Niles Paul wanting to grow into more of a leader, but perhaps the most interesting parts were his opinions on new tight ends coach Wes Phillips and new special teams coach Ben Kotwica.
● Deadspin highlights a guy who applied for the trademark to 'Washington Warriors."
More from The Post:
Poll: Who is the best player on the Redskins?
D.C. Sports Bog: 50 years of Redskins cheerleaders costumes
Post Sports Live: A moral victory or more on Redskins name?
Crowdsourcing the roster: Offensive line
More NFL coverage: Home page | D.C. Sports Bog | The Early Lead | Fancy Stats
Follow: @MikeJonesWaPo | @MarkMaske | @Insider | Insider on Facebook


text:
Perhaps it wasn't the most endearing introduction a new boss has ever made to staff. When Tim Parker met his AA employees as their new chief executive more than two years ago, witnesses say he told those gathered that he was a millionaire who didn't need the money. But what really set alarm bells ringing was when Parker issued an explicit warning: a fair proportion of those gathered in front of him would within a year be out of a job.
Undeniably, Parker is a wealthy man. He scooped a reported £20m when Kwik-Fit, the car exhaust repair firm he previously ran, was sold by its former owner, private equity firm, CVC.
And it seems Parker, retained by CVC to run the AA in what was a £1.75bn takeover, was right about another thing. Some 3,400 AA staff - equivalent to 34 per cent of the workforce - have subsequently lost their jobs.
Harsh and clinical, the secretive world of private equity today faces unprecedented scrutiny. A consortium led by CVC is this weekend working towards submitting a bid for what could be Europe's largest ever leveraged buyout - Sainsbury's - possibly this month. A mooted £9bn offer has focused the minds of concerned politicians, unions and regulators.
Private equity works on the basis of making at least a 20 per cent return on investment in a three-to-seven-year timeframe. Savage cuts to workforces and asset disposals - particularly property - are the preferred route.
Some are worried that private equity risks destabilising delicate financial markets by loading up firms with so much debt they risk failing to meet repayments. Others are angry about how they minimise tax, including, in some cases, by basing themselves in tax havens. These issues will be debated by MPs soon. And union leaders have demanded meetings with Trade Secretary Alistair Darling to outline their concerns
For unions and their workforces, the prospect of dealing with capitalism at its most aggressive is chilling. At the same time there is a sense that unions have found a cause celebre - an issue around which they can get workers to unite.
Today British firms controlled by private equity generate total sales of £424bn, export £48bn and, according to the British Venture Capital Association, account for 2.8 million jobs, equal to 19 per cent of private-sector employees.
Talking to staff at the AA, which is jointly owned by CVC and its industry rival Permira, a picture emerges of a workplace where Parker has made his presence felt. Hours have been extended and intense pressure and the casualisation of labour have stoked a climate of fear. This charge, however, is utterly denied by the company, which blames a derecognised union, the GMB, for painting a false picture of life at the firm.
'The AA's been around a long time. It's well established. It's always been pro membership,' said one AA worker last week. 'Now everyone is driven really, really hard. Everyone is driven by fear.'
Another said: 'We are monitored every quarter. There are three bands. If you are in the lowest band you are performance-managed and once you are down there, it's hard to get out. This puts pressure on staff and affects the service we give.'
Seemingly that service has deteriorated. According to a Which? survey, response time to members has lengthened. Last summer Parker conceded that they may have axed too many patrolmen - 500 (more than 20 per cent). However, the company says that in the latest Which? survey, the AA is recognised as the Best Buy.
There are fierce rows between the GMB and the AA. When Parker took over AA, he denied recognition to the GMB. Leaders of the newly constituted employer-backed AA Democratic Union says this was because the union wanted to dilute the workforce's autonomy within the GMB. The GMB says the AA conspicuously sidelined an effective advocate for staff, as workers were being laid off. It is clear that there was no employee vote on the status of the union. Instead a vote of staff representatives saw 5,000 employees signed up to the new organisation.
The GMB claims 1,000 members stayed with them and their numbers are growing weekly. Whether it is a fight for justice or simply the loss of a large slug of subscription income, it is hardly surprising that the GMB is now launching a fierce campaign to alert the media and politicians to the perceived iniquities of private equity. In this they are joined by the T&G, whose general secretary, Tony Woodley, is campaigning to stop private equity seizing control of Sainsbury's in a bid to protect his 20,000 members there.
There are now serious industrial relations issues at Permira-owned Birds Eye, where there are plans to close a factory in Hull with the loss of 500 jobs.
One of the sector's most prominent operators warned that unrest was the shape of things to come: 'I think Permira have the biggest issues with private equity-based restructuring. Our image is not much helped by the Private Equity charity fiasco [in which the industry's leaders were entertained by a scantily clad pole dancer]. I do not know of any other big rows at present. But they will come.'
It is unfair to paint the entire private equity industry as robber-baron asset-strippers. In many cases the reverse is true. Many of Britain's fledgling technology and creative firms would be nowhere without their investment.
One such business is Fat Face. The leisurewear brand was started by two ski bums who sold T-shirts to extend their Alpine breaks. The business grew into a 25-strong chain of shops with a £7m turnover. The two founders, Tim Slade and Jules Leaver, were keen to sell out. Isis, a private equity firm, bought 40 per cent of the business for £3.5m, although they didn't want the management to leave. 'If they did, all the intellectual property would disappear with them,' said Isis partner Wol Kolade.
Instead, Isis worked with the firm to get them to a position that would allow the founders to leave a few years later. Today Fat Face has more than 100 stores, has created hundreds of new jobs and increased profits substantially. Of course, in smaller concerns, the option to slash costs and sell assets is non-existent. Rather the emphasis is on growth. So the role of private equity is necessarily more benign.
However, in mature businesses there are 'excess' costs and assets. Debenhams was taken private in 2003 only to come back to the stock market barely two years later - with a market value greater than it was sold for and laden with debt.
In the AA a refinancing led to a windfall of £500m that reduced debt, facilitated an employee pension contribution and a dividend for the backers. But financial engineering and employee rights do not tend to mix well. Further conflict will prove that.
In favour: 'Creating long-term value is crucial to what we do'
'Open up. Why are you so secretive? To whom are you accountable? There's too much debt in your deals.' For an industry that is essentially about building businesses and creating jobs, these criticisms seem a bit strange.
Far too much attention is paid to the tiny handful of giant private-equity deals. Over the past year, only about a dozen big deals have gone through, yet speculation about prospective bids that never come to fruition fills the business pages day after day. Meanwhile, not enough attention is paid to the thousands of smaller businesses private equity backs every year.
Then there is the issue of transparency and accountability. A private-equity house is fully accountable to its investors, who are in effect its shareholders. Potential investors receive all the information they could want. Once they have invested, they receive detailed quarterly data that is far superior to anything a shareholder in a public company would get.
And private equity keenly recognises the importance of employees. More private-equity-backed businesses set up staff share-option schemes than firms not so backed. A sense of ownership is at the heart of the private equity model.
The third issue is debt. Debt is negotiated between experienced and responsible parties. It is in no one's interest to put in too much of it. Appropriate levels of debt are set with reference to the strength of the economy and the confidence with which companies can budget their future earnings - and service the debt. Many private-equity deals, especially in smaller firms, are structured with little or no debt; a larger business is comfortable with a higher level and is still able to grow, invest and create jobs.
The ability to create long-term value is crucial to what a private- equity house does. How can it sell a company on unless it can show the new owners it has potential?
We welcome the attention we are attracting. It gives us a chance to champion the significant benefits private equity brings to the economy - and the UK's success in building a world-class industry.
Peter Linthwaite, chief executive, British Venture Capital Association
Against: 'Taxpayers subsidise them'
The case of the AA illustrates why we at the GMB union oppose the unaccountable activities of venture capitalists, their tax relief on loans, and the effect they have on companies, jobs, pensions and the economy. We consider the private status of venture capitalists to be an abuse of company law and of their privilege of limited liability status. The growth in these funds is leading to increased merger and takeover activity, thus generating huge bonuses for the City, while the management teams who run the funds levy very steep charges and commissions. In effect, it is a vehicle whereby the multi-millionaire elite are able to cream off large sums of money away from the public gaze.
The GMB is calling upon Gordon Brown, in his next budget, to end tax relief for interest payments on loans used by venture capitalists to buy firms like the AA, Little Chef and Birds Eye. This relief costs the Exchequer hundreds of millions a year, while giving debt unfair tax advantages over equity.
Rather than the Exchequer receiving tax on these profits, the venture capitalists are able to claim millions in tax relief on the interest payments. So the taxpayer is subsidising the activities of the venture capitalists. When the AA is sold back to the City, the task of reversing the fall in services to customers and ending exploitation of the workforce will erode these profits.
This transfer from taxpayers is now leading to the destruction of household-name companies by venture capitalists, who are saddling these employers with massive debts. This is no small matter. Venture capitalists now own companies that employ 3 million people in Britain.
The GMB is seeking an adjournment debate before the budget to press the Chancellor to end tax relief. The presence of venture capitalists circling Sainsbury's makes this policy change more urgent.
Paul Maloney, GMB senior organiser
How it works
Private equity houses raise billions from pension, hedge and insurance funds, as well as from rich individuals, to acquire private firms or listed groups. They make their money via management or performance fees, although sometimes a private equity firm invests in its own 'buyout fund'.
Historically, they have invested in enterprises that have been deemed too risky to finance via the capital markets or through bank loans, so they have gained a reputation for being prepared to go where others fear to tread.
Typically, they demand an exit route after three to five years, either by refloating firms or selling them on.
After the dotcom bubble burst and interest rates were cut to levels not seen in a generation, private equity became more aggressive, particularly in the leveraged buyout market - where funds furnish a small proportion of the acquisition price and borrow the rest. In recent years, private equity has borrowed bigger amounts, often to provide them and their investors with chunky dividends. And instead of spending five years reorganising a company, some acquisitions have been sold on after less than a year, sparking accusations of greed.
Richard Wachman


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A portrait of Napoleon Bonaparte sold at auction for £15,000 could be worth more than 100 times that after a deep-clean showed it to be the work of one of France's most celebrated painters.
The long-lost portrait had been written off as a "dull and lifeless" copy. It was unloved and dirty, with what were believed to be gravy stains on it.
Yet an academic from the University of Reading has studied the painting after it was cleaned and confirmed that it is by the renowned artist Jacques-Louis David, whose works include the famed Marat at his Last Breath.
Dr Simon Lee, from the university's department of art, insisted the David was genuine and said that although it had yet to be officially valued it could be worth more than £2m. With the Battle of Waterloo bicentenary in 2015, its value could be boosted further.
"People thought it was a copy because it was so dirty," he said. "It had been unloved and the painting looked dead and flat. The restoration revealed it as a powerful, characterful head."
Dr Lee performed a series of checks including comparing it to another David portrait at the Frick Collection. Using a conservator's light, he found that both paintings had remarkably similar mannerisms, modelling and use of drapery.
David painted several portraits of Napoleon, including The Coronation of Napoleon, which currently hangs in the Louvre. The recently unearthed painting shows Napoleon in the uniform of the National Guard in 1813, a time when the British and Prussians threatened to invade France.
The artist was among the foremost European painters from 1780 to his death in 1825 – the most recent sale of his work in 2006 reached £2.1m.
The painting was lost after being hidden ahead of the unexpectedly swift Allied invasion. It was first recorded in a family collection in Scotland before being donated to the Royal Scottish Academy, which sold it to a private collector in New York for £15,000 in 2005.
The academy could not be reached for comment on Sunday.
- More about:
- Artists
- Higher Education
- Louvre
- Painting
- Scotland
- Visual Arts


text:
Home >> Bathroom Vertical Mounted Double Outlet Water Filter Tap Solid Brass Faucet
|Product Name
|Basin Faucet
|Overall Size
|36 x 21 x 18cm/ 14.2" x 8.2" x 7.1" (H*W*T)
|Spout Height
|24cm/ 9.4"
|Water Outlet Dia(Approx.)
|20mm/ 0.78"
|Male Thread Dia.(Approx.)
|20mm/ 0.78"
|Main Color
|Silver Tone
|Chrome Plated, Solid Brass
|Package Content
|1 x Basin Faucet
- Features chrome plated solid brass material, double handle, double outlet, swan neck, filtering net water outlet, 1/4 turn operation, vertical mounted style, 360 degree swivel spout.
- It is a good replacement for the broken basin faucet of your kitchen or bathroom sink.
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text:
Anonymity of the NormMature
Guy gets kicked out. Things happen. NO PLOT FOR YOU
Let me tell you a real story. All you people seem to hear bullshit Hollywood fairytales. Sit tight and listen.
I got thrown out of my house early into my life. 18, exactly. I had nothing. No money, no qualifications, and my parents disowned me completely. Called me dirt. Abused me. Hell, if I was still there I'd probably be thinking of suicide. But I digress.
I left with nothing but the clothes on my back. This being a band shirt for Iron Maiden that I never wore, my average looking coat, denim jeans, and my pretty normal looking trainers. I looked like a fucking idiot. Considering all I ever did was lurk in my bedroom all day doing nothing but tampering with my computer, I had a little bit of experience with I.T. Well, by a little I mean that I know more than those tech support junkies. Now I don't even have my computer. I said goodbye to internet for the time being.
So I started walking away from the seemingly ominous aura emanating from my parents house and made my way to the terrifying prospect of being a tramp, kicking the pebbles on my way.
Hull. East Yorkshire. Fairly big city I guess. Riddled with crime and some of the worst people you'll ever meet. The only thing that could top it is the piss-stained, vermin-ridden prisons used to hold the most batshit insane criminals you could find. I couldn't stomach the thought of people who are worse than the populace of Hull. Call me a cynic, go ahead, come to Hull and meet all the amazing locals, with an average I.Q. of 30 and no real sense of social or life skills. And whilst you're there, think of all the amazing prospects of living homeless here.
Anyways, whilst walking I began thinking to myself. Am I going to die? Will I resort to begging? Will my parents re-integrate me back into the family? How will I ever make a living? Questions circulating in my mind, disputing with myself until I stumble upon a shack of sorts. Abandoned, almost sheet metal, holes in the roof, door. The door was my problem, I needed to kick it down. "Well, here goes" I said to myself. First kick, I feel the shock up my leg, this being amplified by the freezing September air. It hurt like a bitch. It had to be done, if I didn't get into here, I'd most likely die.
Half an hour and multiple kicks later, the door shatters into multiple pieces, and as it did I heard dogs barking, reacting directly to the loud noise. Fucking dogs. I was always a cat person myself. I inspect the inside of what I'd call my home. Nothing much really. A broom, a bed frame that's split into multiple sharp fragments and a bucket. Not exactly home sweet home, but nonetheless, it provided me with shelter. I curled up on the hard, blighted floor and curled up. It took me a while to sleep as my leg was killing me, it was fucking freezing, and my mind was still racing with questions. In regard to begging, that was out of the fucking question. The internet taught me that I should just despise people; they would never help me with anything. I was completely alone at that point, torn apart at my decline in life, it bared too much upon me. I started sobbing, in the foetal position, in the corner of an abandoned shack. Yeah, that was the worst moment of my life so far. I eventually became dizzy and fell into a deep sleep, within the corner of my new abode, the purple sun shining through the hole where the door use to be and the holes within the ceiling, if you would call it that. Thanks, Mother and Father, you got your wish. I was a shitstain on your reputation. I then soon became just another shitstain on the society. It sickens me to look back on myself now, how I could even live, nevermind sleep, like that.


text:
Spring / Summer
Blues on Whyte is closing down Whyte Avenue From June 30-July 2 for a big summer block party!
Bigger and better, Edmonton's International Beerfest is back this April!
Travel around the world in a single weekend; a melting pot of multi-cultural sights, sounds and aromas.
The 5th Annual Edmonton Craft Beer Festival returns in delicious fashion!
Cheer on the chefs that are competing to represent Canada at the World Food Championships!
Nibble and sip your way through the entire city at the ultimate dine-around – Taste of Edmonton.


text:
|Publication number
|Publication type
|Publication date
|Dec 2, 1975
|Filing date
|Jun 12, 1973
|Priority date
|Jun 12, 1973
|Publication number
|Baukal Werner, Kinkel Heinz-Joachim, Robens Erich, Walter Gerhard
|Original Assignee
|Battelle Institut E V
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (2), Referenced by (46), Classifications (7)
|External Links: USPTO, USPTO Assignment, Espacenet
United States Patent 1 [111 3,923,969
Baukal et al. 1 Dec. 2, 1975 [54] CARRIER SYSTEM FOR A DRUG WITH 3,148,124 9/l964 Gaunt 424/22 SUSTAINED RELEASE [75] Inventors: Werner Baukal, Kronberg, Taunus; P i E i sh K R Heinz-J0a Kinkel, Schwalbach. Attorney, Agent, or FirmChristen & Sabol Taunus; Erich Robens, Friedrichsdorf; Gerhard Walter, Steinbach, all of Germany [57] ABSTRACT [73] Assignee: Battelle-lnstitut e.V., Frankfurt am M i Germany A carrier system for a drug which allows the sustained and prolonged release of the drug which is comprised [22] Wed: June 1973 of (i) a porous carrier material which is insoluble or 2 1 ;3 9 404 only slightly soluble in the body, which is in compacted form or powder form and which contains cavities which are connected to the outer surface by nar- [52] US. Cl. 424/19; 424/22; 424/23; row pore necks the mean diameters of the cavities in 424/357 section being over twice as large as the mean internal [5]] ll'lt. CL A61K 27/12 widths of the necks of the pores, and the internal [58] Fleld of Search 424/19-23, width of the necks of the pores being preponderantly 424/357 less than 0.1 um, and (ii) a drug or pharmaceutically active substance is embedded or contained in the cavi- [56] References Cited ties UNITED STATES PATENTS 2,038,694 4/l936 Wiggins 424/23 1 Claim, N0 Drawings CARRIER SYSTEM FOR A DRUG WITH SUSTAINED RELEASEv BACKGROUND OF THIS INVENTION 1. Field of thislnvention The invention relates to a carrier, depot or bonding system for a drug which allows sustained release of the drug and which can be administered orally, externally or by implantation. The carrier material consists of physiologically innocuous, inorganic or organic materials which are totally or almost non-reabsorbable in the body. For its properties as a carrier of active pharmaceutical substances what is decisive is the special porous structure. It comprises so-called inkwell pores, i.e. it contains cavities connected to the outer surface of the bonding substance by passages (pore necks) which are narrow in relation to their diameters. The drug is embedded in the cavities.
2. Prior Art Sustained release preparations make it possible for the dosage of a drug to be accurately controlled over a long period of time and for a plurality of active substances to be released on a set time schedule. A number of methods of obtaining sustained release are already known. For example, the drug may be enclosed in a capsule which will dissolve in the body after a certain amount of time or which allows the drug to diffuse through its porous wall. In the case of microincapsulation, the drug is enclosed in a large number of very small membrane capsules. Tablets may be coated with lacquers to achieve delayed release. The drug may be suspended in water, oil or buffer solutions. The drug may be etherified or esterified to put it in a form in which it is difficult to reabsorb. If the drug is applied as a crystal suspension or a crystal implant, its release will be delayed because its surfaces will be small relative to the amorphous substance. Absorption of the drug in carrier materials which can swell, such as gelatin, cellulose or certain plastics also delay release. If the drug is bonded by adsorption to large surfaces, release will be slow due to the low speed of desorption, as, e.g., in the case of the adsorbate innoculate or vaccine, a result of admixture with aluminium hydroxide. If a powdered drug is compressed together with powdered plastics, a porous tablet will form in which the plastic material will partly cover the surface of the powdered drug and will delay its release (see British Pat. No. 808,014, German Pat. No. 1,201,950 and U.S. Pat. No. 3,279,996).
BROAD DESCRIPTION OF THIS INVENTION The problem solved by this invention was the developement of a carrier, bonding or depot system for sustained release preparations which has the following advantages as compared with known carrier means: 1 it is adapted to incorporate various solid or liquid drugs, independent of their chemical nature, solubility and mechanical or thermal stability, and (2) the rate at which the drug is released from the carrier substance into the body remains constant over a selectable period of time independently of the amount of stored drug or varies in accordance with a schedule or program.
According to this invention, these requirements are fulfilled when the drug, medicament or pharmaceutically active substance is incorporated in a porous car rier substance which is insoluble or only slightly soluble in the body (human and/or animal) and when the pores of the carrier substance each have an inkwell shape. In
the literature (see, e.g., G.J. Gregg and K.S.W. Sing, Adsorption, Surface Area and Porosity: London, Academic Press (1967), page ff), inkwell pores are pores which, in the simplest case, comprise a cavity which opens towards the outside through a narrow neck. With these pores two essential parameters can be chosen independently of one another: (i) the volume of the cavity and (ii) the dimensions (internal width and length) of the neck of the pore. If the volume of the neck is small relative to the volume of the cavity, the amount which can be stored in the pores will depend virtually only on the volume of the cavity, while the timing of the release or temporal course of delivery into a surrounding medium will be affected predominately by the dimensions of the pore neck. The pore systems having inkwell pores which are used in this invention are composed ofa plurality of pores of different shapes and sizes, and the cavities are frequently interconnected and open to the outer surface of the porous substance through a plurality of necks. Pore systems of such very complex construction can be described, in their adsorption behavior action, as an inkwell shape, if the diameters of the cavities are on the average more than twice as large as the associated pore necks. This invention involves or uses only those inkwell pores in which the necks are within the microand mesopore range, i.e., having internal widths or diameters of less than 0.1 u, m down to the diameter of only a few atoms diameters (see, e.g., D.l-I. Everett and RH. Ottewill, (eds), Surface Area Determination London, Butterworths (1970) page 63).
For the sustained release preparation according to this invention, a porous carrier material which is insoluble or dnly slightly soluble in the body is used. The dimensions of the pores in such a material is virtually invariable during the period or time of application, so the rate at which the stored drug is discharged (rate of delivery) remains constant so long as the concentration in the cavities does not drop.
After the application or taking of a sustained release preparation comprised of an insoluble carrier substance having inkwell pores and a drug incorporated therein, body fluid first enters the pores and dissolves the drug or mixes with it. The drug then diffuses outwardly via the pore necks filled with body fluid while more body fluid diffuses inwardly. The drug initially has saturation concentration in the cavities and almost zero concentration outside (in the body). With regard to the timing of the release of drug when the starting processes are over, one should distinguish between the following two cases:
1. The active substance is soluble only to a limited extent in the body fluid and forms a separate phase. In this case the concentration of active substance in the solution in the cavity, and with it the rate of release or delivery, will remain constant until the separate phase has disappeared. It will then decrease.
2. The active substance can be mixed with the body fluid in any ratio. The concentration of active substance and the rate of release or delivery will then decrease continuously. The neck of the pore acts as a resistance to or check on the flow of active'substance and lengthens the period of release.
If the dimensions of the necks in the pore system vary widely, the pores with short and wide necks will empty first, while the concentration in the other pores will remain constant for longer. The rate of release from such a pore system will decrease with the passage of time.
3 With a suitable combination. provision can be made for the drugs to be released with any timing, e.g.. in approximately linear progression. By mixing pore systems of different types. filled with different active substances. programmed release of combinations of active substances also are obtained.
The rate of discharge from a carrier system with inkwell pores can be estimated from their dimensions, as demonstrated by the following example. The composition is taken to be a tablet with a volume of l() mm less the cavity volume V of 10 mm. The cavities are connected to the surface by a l0 not very different pore necks with a mean cross-sectional area of A 10 nm and a mean length of 0.] am. The concentration of active substance in the cavities when the starting processes are over is 0.1 ,umol/mm, while the concentration c, in the body in the vicinity of the tablet is 0. Assuming a coefficient of diffusion of l) l0m .s. then according to Ficks Law the following is obtained. in simplified form, for the rate of release f1 (see, e.g., C.D. Hodgman. Handbook of Chemistry and Physics", 44 ed.. Cleveland, Chemical Rubber Publishing 1961, page 2274).:
The rate of discharge of active substance would accordingly remain constant for longer that /2 day. given low solubility.
With a l0- and l am. one would obtain ri l0" mol.s and a period of release t of 1.6 years.
Solids with an inkwell pore structure are known. they are used. for example. as adsorbents, catalysts or catalyst carriers. Suitable materials which can be used as the carrier material having an inkwell pore structure include oxides, ceramic and metallic materials and plastics which are physiologically innocuous. The preparations may be used as a powder or in a compact or compacted form. such as. tablet form.
Oxides such as silicon oxide, aluminium oxide. zirconium oxide, etc.. can be prepared in highly porous form from the corresponding hydroxide gel by dehydration and drying at an elevated temperature (see. e.g.. R.E. Kirk and D.F. Othmer. Encyclopedia of Chemical Technology". Vol. l2. page 345 ff.. New York. lnterscience Publishers 1954); and E. Robens and G. Sandstede. Z. lnstrumentenkunde" 75 (1967). page I77). In another process (see K.S. Mazdiyasny. (.T. Lynch and 1.8. Smith. J. Am. Ceramic Soc. 48 (1965). pages 372 375) alcoholates dissolved in organic solvents are converted, by hydrolysis and subsequent drying. into oxides with crystallites and pores in the sub-micron range.
Metallic anc ceramic substances as well as plastics can be sintered together to form porous bodies by compressing powders. with a simultaneous or subsequent heat treatment. Porous structures of the desired type can be obtained by thermal disintegration of hydrates or salts. e.g.. in the thermal decomposition of nickel formate dihydrate (P.(i. Fox. I. Ehretsmann and CE. Brown. J. Catalysis 20 (1971). pages 67 73). The Rancy process may be used to prepare metallic powders of very high micro-porosity. A metal alloy is first produced and one component of the alloy is then dis solved out. The remaining metal re-crystallizes. and mi cro-crystallites and corresponding pore systems are formed (see. e.g.. H. Krupp. H. Rabenhorst. G. Sandstede. G. Walter and R. McJones. J. Elektrochemical Soc. 109(1962). pages 553 557 Porous plastics can be made by various. already-known methods. e.g.. by using one of the freeze drying techniques. In the processes mentioned herein. the pore structure can be modified by varying the manufacturing conditions.
The active substance may be deposited by steeping the bonding material in the liquid or molten drug. It may be necessary first to cleanse the material of sub stances (such as water) which have been embedded in the cavities during manufacture. This can be done. e.g.. by drying under vacuum at an elevated temperature. Solid drugs may be dissolved and incorporated or placed in the bonding material by steeping the latter in the solution. The solvent can then be removed by vaporization. if the drug is vaporizable or sublimable. it may be deposited or placed in the cavities by condensation out of the gas phase. Finally, the drug may be mixed with the starting materials before the preparation of the carrier material. As the carrier material is made. the drug becomes enclosed in the pores which are formed.
Preparations made in this way can be used in powder form. The powder may be processed as an emulsion in a liquid in which the drug is insoluble or compressed into tablets. The carrier material in pellet or tablet form may be coated in a known manner with lacquers in order to achieve a further delay in the action of the drug.
As used herein the term drug includes medicaments. drugs, pharmaceutically active substances. etc.
The drug can be. for example: laxatives. such as. oxyphenisatin acetate; vitamins and nutrients; parasympatholytics. such as homatropine methylbromide or phenobarbital; hormones; steroids; anti-infectives; analgesics. such as, phenacetin. aspirin and caffeine; narcotics; anesthetics; sedatives and tranquilizers, such as, chlordiazepoxide HCl and diazepam; antihallucinatory agents; sympathominetics; hypo-allergenic agents; antigens; antihistamines. such as. bromodiphenhydramine hydrochloride. methapyrilene fumarate and chlorpheniramine maleate'. vasoconstrictors; antibiotics; enzymes; anticoagulants. vasodilators; lipotropic agents; cerebral stimulants; bronchodilators; muscle relaxants;
diuretics; etc.
The carrier material consists of physiologically harmless inorganic or organic materials which cannot be absorbed or only very slightly absorbed in the body. Its special porous structure is critical for its use as a carrier of pharmaceutically active ingredients. It contains socalled inkwell pores. that is to say it contains cavities or hollow spaces. which are connected by channels (necks of the pores). which are narrow in relation to their diameter of the main cavity bodies, with the outside surface of the carrier material. The drug is housed in the hollow spaces.
DETAILED DESCRIPTION OF THIS INVENTION In the following examples and throughout the rest of this document, all parts. percentages and ratios are on a weight basis unless otherwise stated or obviously so to one ordinarily skilled in the art.
EXAMPLE I Ben/.oie acid in silica gel An excess quantity of waterglass solution was stirred drop by drop into dilute hydrochloric acid at 5()"C. A jelly formed, which was washed free of electrolyte and dried first at 100C, then at 300C. A piece of the resultant lumps of silica gel was degassed under vacuum and, again under vacuum, impregnated with molten benzoic acid (as a sample drug). The lump was then compressed in polyethylene powder in such a way that the silica gel was completely sheathed with a porous film of polyethylene. 'Ihe tablet was put into water and the timing of the variation in conductivity resulting from the escape of benzoic acid was measured. A uniform increase in conductivity was observed over several hours.
EXAMPLE 2 l-Propyll -cyclohcxyl-2-methylaminopropane-hydrochloride in aluminium oxide By the method of Mazdyiasni. Lynch and Smith, aluminium-iso-propylate was dissolved in benzene, and a mixture of water and iso-propanol were added dropwise while stirring. Both mixtures contained the drug almost to the point of saturation. The jelly which formed was dried at l()l)c. As in Example I the rate of 6 discharge was ascertained by measuring the conductivity, and the lump disintegrated into small particles. As first there was a strong discharge of the drug, which changed to a slow discharge after about a quarter of an hour. A constant rate of discharge could be observed for 2 days.
The initial strong discharge was decreased by washing and then drying the lump of the preparation.
What is claimed is:
l. A carrier system for a drug which allows the sustained and prolonged release of the drug which consists of i. a porous carrier aluminium oxide material which is insoluble or only slightly soluble in the body which is in dried jelly lump form which disintegrates into small particles and which contains inkwell pore cavities which are connected to the outer surface by narrow pore necks. the mean diameters of the inkwell pore cavities in section being over twice as large as the mean internal widths of the necks of the inkwell pores, and the internal width of the necks of the inkwell pores being preponderantly less than 0.1 pm and ii. a drug or pharmaeeutically active substance which is embedded or contained only in said inkwell pore cavities, and which jelly has been formed by stirring together dropwise a mixture of aluminum isoproponatc dissolved in benzene and a mixture of water and isopropanol, both mixtures containing the drug almost to the point of saturation. and drying the jelly which formed. to a lump which disintegrates into small particles.
|Cited Patent
|Filing date
|Publication date
|Oct 15, 1930
|Apr 28, 1936
|Davision Chemical Corp
|Jun 12, 1962
|Sep 8, 1964
|Gaunt William E
|Method of preparing sustained release pharmaceutical tablets
|Citing Patent
|Filing date
|Publication date
|Mar 21, 1975
|Mar 22, 1977
|Bristol-Myers Company
|Apap tablet containing fumed silica and process for manufacturing same
|Oct 1, 1979
|Mar 3, 1981
|Beiersdorf Aktiengesellschaft
|Pharmaceutical tablet composition
|Oct 29, 1979
|Aug 4, 1981
|Beecham Group Limited
|Intramammary compositions
|Feb 12, 1980
|Oct 6, 1981
|Kyoto Ceramic Co., Ltd.
|Granular ceramic carrier for administration of medicines and medicine supported therein
|Sep 13, 1984
|May 6, 1986
|Standard Telephones And Cables, Plc
|Controlled release system
|Apr 22, 1985
|Oct 14, 1986
|Ppg Industries, Inc.
|Animal feed supplement
|Aug 21, 1986
|Jan 19, 1988
|E. I. Du Pont De Nemours And Company
|Manufacture of hollow fine tubular drug delivery systems
|Nov 28, 1988
|Apr 16, 1991
|Vectorpharma International S.P.A.
|Pharmaceutical compositions with controlled release, and a method for their preparation
|Oct 2, 1990
|Dec 15, 1992
|Glaxo Inc.
|Medical capsule device actuated by radio-frequency (rf) signal
|Apr 21, 1989
|Sep 28, 1993
|Akzo Nv
|Active agent containing solid structures for prolonged release of active agents
|Aug 29, 1991
|Mar 29, 1994
|Hagiwara Research Corp.
|Antimicrobial composition having resistance to heat and weathers
|Apr 17, 2000
|Feb 18, 2003
|Genevac Limited
|Methods and apparatus for preventing sample loss
|Aug 17, 2000
|Aug 5, 2003
|Technology Holding, Llc.
|Composite material and process for increasing bioavailability and activity of a beneficial agent
|Nov 30, 1995
|Dec 14, 2004
|Kaken Pharmaceutical Co., Ltd.
|Crosslinked gelatin gel preparation containing basic fibroblast growth factor
|Nov 13, 2003
|Nov 13, 2007
|University Of Virgina
|Medical devices having porous layers and methods for making same
|Aug 20, 2007
|Apr 8, 2008
|Australian Nuclear Science & Technology Organisation
|Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
|Aug 20, 2007
|Apr 8, 2008
|Australian Nuclear Science & Technology Organisation
|Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
|Aug 20, 2007
|Apr 15, 2008
|Australian Nuclear Science & Technology Organisation
|Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
|Jul 11, 2008
|Sep 8, 2009
|Australian Nuclear Science & Technology Organisation
|Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
|Feb 10, 2006
|May 11, 2010
|Medtronic Vascular, Inc.
|Method for loading nanoporous layers with therapeutic agent
|Feb 23, 2010
|Feb 28, 2012
|Medtronic Vascular, Inc.
|Method for loading nanoporous layers with therapeutic agent
|Feb 10, 2006
|May 28, 2013
|Medtronic Vascular, Inc.
|Methods for using a stent having nanoporous layers
|Jun 27, 2003
|Apr 15, 2004
|Joshi Ashok V.
|Composite material and process for increasing bioavailability and activity of a beneficial agent
|Nov 13, 2003
|Jul 29, 2004
|Setagon, Inc.
|Medical devices having porous layers and methods for making same
|Aug 13, 2004
|Mar 31, 2005
|Whye-Kei Lye
|Medical devices having porous layers and methods for making the same
|Aug 10, 2005
|Jun 8, 2006
|Lye Whye K
|Medical devices having nanoporous layers and methods for making the same
|Feb 10, 2006
|Aug 31, 2006
|Owens Gary K
|Medical devices with nanoporous layers and topcoats
|Feb 10, 2006
|Aug 31, 2006
|Owens Gary K
|Medical devices having nanoporous bonding layers
|Feb 10, 2006
|Aug 31, 2006
|Joshua Spradlin
|Nanoporous layers using thermal dealloying
|Feb 10, 2006
|Aug 31, 2006
|Owens Gary K
|Method for loading nanoporous layers with therapeutic agent
|May 11, 2006
|Nov 30, 2006
|Whye-Kei Lye
|Stent with nanoporous surface
|May 9, 2006
|Dec 7, 2006
|Gary Owens
|Dealloyed nanoporous stents
|May 9, 2006
|Dec 7, 2006
|Gary Owens
|Dealloyed nanoporous stents
|May 11, 2006
|Dec 7, 2006
|Whye-Kei Lye
|Medical devices having porous layers and methods for making the same
|May 10, 2006
|Dec 7, 2006
|Whye-Kei Lye
|Nanoporous stents with magnesium leaching
|May 10, 2006
|Dec 7, 2006
|Whye-Kei Lye
|Nanoporous stents with improved radiolucency
|Aug 20, 2007
|Dec 20, 2007
|Australian Nuclear Science & Technology Organisation
|Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
|Aug 20, 2007
|Jan 3, 2008
|Australian Nuclear Science & Technology Organisation
|Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
|May 24, 2007
|Apr 10, 2008
|Gary Owens
|Nanoporous stents with enhanced cellular adhesion and reduced neointimal formation
|Aug 20, 2007
|May 22, 2008
|Australian Nuclear Science & Technology Organisation
|Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
|Jul 11, 2008
|Nov 6, 2008
|Autralian Nuclear Science & Technology Organisation
|Controlled release ceramic particles, compositions thereof, processes of preparation and methods of use
|Feb 3, 1982
|Jul 5, 1983
|Beecham Group P.L.C.
|Intramammary compositions
|Feb 13, 1980
|Aug 21, 1980
|Kyoto Ceramic
|Koerniger keramischer traeger zur verabreichung von arzneimitteln und darin aufgenommenes arzneimittel
|Dec 2, 1988
|Oct 11, 1989
|VECTORPHARMA INTERNATIONAL S.p.A.
|Pharmaceutical compositions with controlled release, and a method for their preparation
|Aug 11, 2005
|May 23, 2007
|Setagon, Inc.
|Medical devices having nanoporous layers and methods for making the same
|Aug 11, 2005
|Apr 23, 2008
|Setagon Inc
|Medical devices having nanoporous layers and methods for making the same
|U.S. Classification
|424/468, 424/484, 514/770, 424/469
|International Classification
|Cooperative Classification
|European Classification


text:
Their backdrop showed a man relaxing in his bath, about to be rudely awakened by a plugged-in toaster falling from above. If only Fall Out Boy could have shown such spark.
No matter how much they spun round, pogoed or jumped off speaker stacks, the latest heroes of parental-guidance punk showed a distinct lack of drama. Perhaps they had too much to say: the Chicago outfit have become mainstream pin-ups thanks to an audacious fusion of emo-rock's searing honesty and the pop sensibility of Green Day.
Also mixed in was a smidgen of straight-edged fundamentalism (no drugs or booze for three members), alongside a set of emotional problems topped by bassist Pete Wentz's overdose on prescribed meds for anxiety attacks. Given his particularly cute looks, and as their heart-on-sleeve spokesman, Wentz is central to Fall Out Boy's vilification by the hardcore fraternity. Bright and articulate, the college-educated lyricist also plays the role of entrepreneur, with his own clothing range plus a record label that has unleashed the more rhythm-based band Panic! At The Disco as well as The Hush Sound's folk-based style. To top it all, Fall Out Boy are mates with Jay-Z.
The band emerged to the sound of Bon Jovi's "Living On A Prayer", an odd choice. Wentz and guitarist Joe Trohman, at least, constantly urged the crowd to participate, when they were not attempting to outdo each other in risky leaps over podiums and steps. The singer, Patrick Stump, meanwhile, hidden under a tightly worn trucker's cap, kept himself busy by playing the more complex guitar patterns and unleashing his extraordinary voice. He boasts the biggest set of lungs since the glory days of David Coverdale but was unable to add enough character to differentiate between Wentz's two types of song. Wentz writes so densely that the vocalist struggled to fit in the words.
Their only chance to make an impact was to cram in enough musical tics to suggest attention-deficit disorder, as sudden changes of pace and rapid fills instead of solos kept us on edge. Most successful was the hit single "Sugar, We're Going Down", with its slabs of industrial sound crowbarred into a three-minute pop structure. "The Music Or The Misery" suggested the band were becoming less fidgety. It was very slick, but with constant calls to join the Fall Out Boy "family", you wondered if this would be a lasting commitment or a short-term fling.
Civic Hall, Wolverhampton (01902 552121), tonight
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Progesterone receptor (PR) modulators have evolved both structurally and mechanistically over the past half-century. Classical steroidal PR agonists continue to play an important role in women's health such as in oral contraception and post-menopausal hormone therapy whereas steroid-based PR antagonists and selective PR modulators are being evaluated… (More)
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Structural modification of a virtual screening hit led to the identification of a new series of 4-[3-aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols which are potent and selective inhibitors of the norepinephrine transporter over both the serotonin and dopamine transporters. One representative compound S-17b (WYE-103231) had low… (More)
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text: Top 10 NFL preseason games foxsports Oct 20, 2016 at 4:57p ET Top 10 preseason games Exhibition NFL games will never carry the same significance as the real ones that begin in early September. Even so, Wednesday's announcement of the league's 2012 preseason schedule (exact dates have not been set for all games) still gives fans something to get excited about. Those contests will provide the first look at star veterans taking the field in different uniforms, such as longtime Indianapolis Colts quarterback Peyton Manning wearing orange and blue in Denver. Highly touted rookies such as Andrew Luck and Robert Griffin III also will be making their NFL debuts, as will six new head coaches. Alex Marvez takes a look at 10 of the most intriguing preseason games of 2012: San Francisco vs. Oakland Sadly, this annual crosstown game won't be played in 2012 because of what transpired during last year's matchup at Candlestick Park. Fan violence resulted in 70 ejections, 80 calls for medical attention and two parking-lot shootings, even though the stadium was less than 70 percent full. The Raiders and 49ers had met in the preseason for 11 straight years and 39 times overall since 1967. New Orleans vs. Arizona in Canton, Ohio (Hall of Fame Game: Aug. 5) The first preseason game always generates the most excitement from football-starved fans, but this Saints-Cardinals matchup will draw headlines for another reason. It's the Saints' first game since the bounty scandal that rocked the franchise and led to the season-long suspension of head coach Sean Payton. At this point, Payton's replacement is unknown (pending the outcome of his appeal), although Bill Parcells and assistant head coach Joe Vitt are two strong candidates. Last year's Hall of Fame game was canceled because of labor strife between the league and NFL Players Association. Denver at Chicago (Week 1: Aug. 9-13) Peyton Manning's first Broncos game will come against a team quarterbacked by one of his predecessors — the Bears' Jay Cutler. This also marks the Chicago premiere of former Broncos wide receiver Brandon Marshall, who was one of Cutler's favorite targets in Denver from 2007-08. Conversely, this game could mark the beginning of Brian Urlacher's final season with the Bears. The star linebacker will be 34 in the final year of his contract. Tennessee at Seattle (Week 1: Aug. 9-13) Although teams dislike having to travel long distances for preseason games, Titans quarterbacks Matt Hasselbeck and Jake Locker won't complain. A Seahawks starter for a decade (2001-10), Hasselbeck will get his first opportunity to play in Seattle since joining the Titans as a free agent in 2011. An inspired effort will help Hasselbeck in his quest to keep his starting job ahead of Locker, a University of Washington standout before being chosen by Tennessee with the No. 8 overall pick in 2011. For Seattle, free-agent acquisition Matt Flynn will make his Seahawks debut as he jostles with Tarvaris Jackson to start at quarterback. New York Giants at New York Jets (Week 2: Aug. 16-20) This is a dream for New York's tabloids. Not only did the Giants' Super Bowl XLVI victory add more fuel to an already heated crosstown rivalry, quarterback Tim Tebow will make his home debut for the Jets. Detroit at Baltimore (Week 2: Aug. 17 on FOX) San Francisco's Jim Harbaugh and Detroit's Jim Schwartz nearly came to blows during the 2011 regular season during the customary postgame handshake between head coaches. Harbaugh's more mild-tempered brother and Baltimore head coach, John, now gets a shot at Schwartz's Lions in what could be a precursor to a Super Bowl XLVII matchup. Dallas at San Diego (Week 2: Aug. 16-20) Call this the Disappointment Bowl, as both teams failed to fulfill the Super Bowl hype that surrounded them in the previous decade. Expect the Cowboys to keep an eye peeled on San Diego's backups for potential acquisitions after final roster cuts. Dallas was able to get an up-close look last preseason at wide receiver Laurent Robinson, who later was released by the Chargers and signed by the Cowboys — and then caught 54 passes for 858 yards and 11 touchdowns. Indianapolis at Washington (Week 3: Aug. 23-26) This game should showcase the two top selections in April's draft — quarterbacks Andrew Luck and Robert Griffin III. Luck will be playing for Indianapolis, barring an unexpected change-of-heart by the Colts with the No. 1 overall pick. Both rookies will also get extensive playing time in a Week 3 preseason setting that has traditionally served as NFL teams' dress rehearsals for the regular season. Atlanta at Miami (Week 3: Aug. 23-26) The Falcons will be trying to put the finishing touches on the offensive and defensive systems being implemented by new coordinators Dirk Koetter (offense) and Mike Nolan (defense). For the Dolphins, Matt Moore and David Garrard could be making their final bids to start at quarterback if Miami is still undecided at this point of the preseason. Minnesota at Houston (Week 4: Aug. 29 or Aug. 30) If he hasn't returned already, Vikings running back Adrian Peterson will have this final preseason opportunity to retake the field before Minnesota's regular-season opener. Peterson suffered a serious knee injury in December against Washington but is targeting a Week 1 return. Next Gallery 56 Nike launches new line of NFL uniforms Start Gallery »


text:
In a painting of Tyne Cot Cemetery in Belgium, Whangarei Heads artist David Foley has highlighted one headstone in a row of identical graves of New Zealand soldiers.
On the pen and wash painting he completed in 2011, Foley has written "Known unto God - a New Zealand Soldier, Passchendaele."
Foley's original painting is on permanent display at the National Army Museum, Waiouru.
The largest Commonwealth War Graves Commission cemetery on the Western Front, Tyne Cot contains more New Zealand World War I graves than any other single cemetery.
Sitting on the strategic high ground from which the Germans looked down across the Allied forces, it is a historic site of the battle of Passchendaele.
Within its flint walls are the graves of almost 12,000 dead from World War I, 8300 of them unidentified. The entire rear of the cemetery is occupied by a curved Memorial to the Missing, commemorating another 35,000 soldiers who have no known graves.
Along with many Australian fallen, it holds 520 graves of New Zealanders, 322 of them unidentified.
The New Zealand Apse in the memorial commemorates 1176 New Zealanders who have no known graves. The cemetery covers 34,941sq m.
Nearby, at Buttes, is another New Zealand Memorial to the Missing, and a third is at Messines.