text:
The lifeblood of the clever property spotter who wants to stay ahead of the game is knowledge. So the insiders' hot tip of the week is: Bloomsbury. This central London district has all the ingredients for an elegant purchase. It is a historic area, with some fine architecture and is already enjoying a residential renaissance.
And now it is poised for a £1 billion makeover to take place over the next four years, all under the supervision of the key landlord, Bedford Estate, and a local business partnership.
Georgian buildings that spent the 20th century as offices are now being converted back into homes
Regeneration includes reinstating a traditional high street leading towards Russell Square and the British Museum. Showpiece residential and office developments are being built, while smaller-scale refurbishments of barristers' chambers and university departments are spawning more homes, and two new estate agents have already opened to cope with the newcomers.
With Farringdon, King's Cross and St Pancras on the doorstep, the transport connections are superb, with trains to everywhere from Perth to Paris, a Tube hub with five lines and direct rail links to four of London's five airports.
Emerge from Russell Square station through the sea of bemused tourists and you could be forgiven for not seeing the residential opportunities at this early stage in the renovation plan. But turn a couple of corners and you discover a district of elegant Georgian squares and hidden mews offering flats in a wide price range and outstanding period houses.
Bloomsbury has been a residential district for more than three centuries, owing its existence to the nobility — the grand Southampton and Bedford families — who developed the area as one of the capital's first planned suburbs.
Small tracts are still owned by public school trusts such as Rugby and there is a big academic presence in the form of colleges (University of London) and hospitals (Great Ormond Street).
Many of its Georgian buildings spent the 20th century as offices but are now returning to domestic use. Villagey areas around Lambs Conduit Street, Flaxman Terrace and Museum Street are attracting new galleries and restaurants, with renovated flats above. Refurbished Russell Square, once a magnet for rough sleepers, is now a recreational space for locals with a rebuilt café that has won design awards.
London's largest Waitrose has opened at the renovated Brunswick Centre, the iconic Sixties complex. Bedford Estate, the major freeholder, is instigating streetscape improvements and grooming better-quality retailers. Work has started on a parade of shops at Store Street, a key east-west "spine route".
The estate regained control of premises after the expiry of 80-year leases and is refurbishing 25,000sq ft of space, to be let to independent retailers.
Boutique apartments and a restaurant are being built on the site of a disused petrol station in the same street. Here, too, is One Alfred Place, the private members club founded by Pink Floyd drummer Nick Mason.
© Barry Phillips
Bloomsbury's bohemian character has always appealed to radicals and romantics. It is a child-friendly place and more families are moving to the area as the supply of houses increases, but it lacks schools. Whimsically, a sign reads, "Parents must be accompanied by children at all times" at Coram's Fields, a seven-acre sanctuary in Bloomsbury run by London's Coram charitable trust for children, and dedicated to under-16s.
Values have yet to rise above £1,000 a sq ft — less than half the price of Chelsea and Kensington
The Bedford Estate's housing portfolio includes mansion flats and modern apartments. A pair of listed five-storey Georgian houses overlooking splendid Bedford Square have been converted into nine rental apartments, priced from £500 to £875 a week. With their elegant, fanlight front doors and tall-windowed drawing rooms, the homes offer a chance to live in the grandest of surroundings.
Colonnade is a mews development of nine new townhouses tucked away behind Guilford Street. Prices from £999,000 to £1,295,000. Call estate agent Robert Irving Burns on 020 7927 0619. Four more modern mews houses have been built on the site of former workshops at Brownlow Mews. These range up to 1,800sq ft and have outside space on each of the three levels. Prices from £1.75 million. Call Hurford Salvi Carr on 020 7299 3322.
© Rebecca Reid
A five-storey, modernised Georgian house on Coptic Street is selling for £1.8 million. Call Winkworth on 020 7240 3322.
Doughty Street, close to the Inns of Court, is one of Bloomsbury's best addresses. A listed, freehold corner property spread over five floors and with a roof terrace comes with planning consent for conversion back to residential. Price: £2.3million. Call 020 7927 0619. Charles Dickens lived in a neighbouring property, now a museum dedicated to him. Check out Mecklenburgh Square, which borders Coram's Fields. Big, unrenovated houses can be picked up for about £1.5 million.
"Properties are better value than many newcomers to the area expect," says Carl Schmid of estate agent Fyfe McDade. Values have yet to rise above £1,000 a sq ft — less than half the price of Chelsea and Kensington.
Prices start at about £220,000 for a basic studio. Expect to pay £500,000 for a good two-bedroom flat. Pied-à-terre buyers and parents buying for student sons and daughters make up a large chunk of the market — the local student population is about 20,000 and growing, meaning a Bloomsbury pad is a good investment.
Follow us on Twitter @HomesProperty, Facebook and Instagram
- More about:
- Gallery

subset: commoncrawl


text:
November 2013, TruckingInfo.com - WebXclusive
By Truckinginfo Staff
OSHA wants you to train your workers in Hazard Communication, and wants you to do it by Dec. 1 of this year. The trick? It's a totally new curriculum. Hazard Communication — more commonly known as the "Right to Know" rule about hazardous chemicals in the workplace — is the most frequently cited rule in OSHA.
Tags: Hazmat, Drivers, Driver Training, Instructional Technologies, OSHA
August 2013, TruckingInfo.com - Feature
By Jim Beach
Cargo Transporters, Claremont, N.C, wasn't doing much re-occuring driver training other than a few defensive driving classes, but in 2010 decided to require six hours of either online or classroom training. It was so successful that in 2011 they increased it to eight hours, according to President Dennis Dellinger.
Tags: Technology, Information Technology, Driver Training, J.J. Keller, PeopleNet, Instructional Technologies
We offer e-newsletters that deliver targeted news and information for the entire fleet industry.
Scott Sutarik from Geotab will answer your questions and challenges
Steve Carlson from Xantrex will answer your questions and challenges
On the Spot: U.S. Xpress Max-imum Tech Competition [Video]
Focus On... Volvo's VNR Regional Haul Tractor [Video]
On the Spot: Volvo Trucks VNR Regional Tractor [Video]
On The Spot: International RH Regional-Haul Tractor [Video]
East Manufacturing Offers New Lightweight Tipper Trailer
Momentum's Tailgate System Designed for Refuse Trucks
Kit Designed to Clean Spills Around Large Trucks
Penray Kit Restores Headlight Covers


text:
The HamiltonBuhl MagnaScreen is the most economical and easy way to magnify your smartphone screen to comfortably watch and share the screen.
Hamilton Buhl AA Alkaline BatterySoldseparately. Case quantity available, 60 pieces.
Hamilton Buhl AAA Alkaline Battery. Sold separately. Case quantity available, 60 pieces.
The Hamilton Buhl 9V Alkaline Battery. Soldseparately. Case quantity available, 12 pieces.
Hamilton Buhl C Alkaline Battery. Soldseparately. Case quantity available, 12 pieces.
Hamilton Buhl D Alkaline Battery. Soldseparately. Case quantity available, 12 pieces.
3D Virtual Reality Video and Stills ViewerThe HamiltonBuhl 3D Virtual Reality Viewer is a fold-out cardboard headset that instantaneously transforms your smartphone into a complete 3D Viewer.
HamiltonBuhl 8 Position Jackbox with Individual Volume ControlsThe JBP8VA Jackbox delivers stereo sound for up to 8 students and includes volume controls for personalized listening levels!
HamiltonBuhl Portable Folding Bluetooth KeyboardThis mini folding Bluetoothwireless keyboard lets you enjoy supreme convenience and portable typing anywhere.
Roll-up Bluetooth Keyboard!The HamiltonBuhl RUI-KB full-size, roll-up Bluetooth wireless, universal keyboard lets you enjoy supreme convenience and portable typing anywhere.
HamiltonBuhl Induction Speaker Looking for a portable speaker that doesn't require wires, wifi, configuration or pairing? Then you are looking for HamiltonBuhl's IND-CUBE2 Induction Speaker!
HamiltonBuhl BT-S7 BluetoothCone SpeakerThis wireless, portable speaker provides high quality sound in a small package!The rugged ABS silicone speaker plays music or other audio via Bluetooth.
HamiltonBuhlBTD- CUBE7 Portable Wireless BluetoothAmplifierPower your music with this handy wireless Bluetoothspeaker! Get quality sound from this small yet powerful amplifier.
Unlock Incredible New Experiences with HB Spectra VR, Virtual Reality Headset!The HamiltonBuhl Spectra VR is the affordable yet high-quality virtual reality goggles needed to instantly transform your smartphone into a new reality.
Hamilton's IND-DOCK3 Induction Speaker Looking for a portable speaker that doesn't require wires, wifi, configuration or pairing? Then you are looking for HamiltonBuhl's Induction Speaker!
HamiltonBuhl Rechargeable BluetoothSpeaker for Tablets or Smart Phones. The HamiltonBuhl BT010 is a Bluetooth speaker with 10 watts of power for best sound quality.
Adjustable Gooseneck Tablet Table StandHamiltonBuhl's ISD-TMG Adjustable Tablet Stand with table clamp lets you use your device hands-free.
Soft camera carry bag. One (1) year warranty.
Hamilton's ISD-FS2 Adjustable Tablet Stand lets you use your device hands-free. The Adjustable Tablet Stand is compatible with almost any tablet and most eReaders measuring 7" x 10" or less.
Large, durable, plastic, lockable carry case for Hamilton listening centers. Lock not included.
Keyboard Shelf for HamiltonBuhl CartsAccessory keyboard shelf for HamiltonBuhl carts made from heavy gauge steel with durable powder-coat finish.
Ergonomic hand free stand for iPad and 7"-10" tablets Height adjustable from 37" to 57.9" Rotates 3600 offering vertical & horizontal views 180 degrees tilt adjustment Stable weighted base
Tripod stand for Hamilton Portable PA Systems: For Hamilton Venu100 and PA85 PA Systems Compatible with pole-mount speakers and PA systems Speaker Stand.


text:
Nate's Firepole Fail (To The End)
- Size: 480px
- Quality: High
- Size: 10.35 MB 348.69 KB
This Gif entitled Nate's Firepole Fail (To The End) was created from the youtube video 3 years ago. It uses 18 frames per second and is displayed at 480px resolution. This animated image plays for 6 seconds, was built with high quality and an estimated weight of 10.35 MB for download. This animation was originally created from the Nates Firepole Fail video from 00:09 to 00:15.
Flag This GifSend


text:
You cower behind your table.
You duck and cover your face with your hands. There's a sickening crunching sound, and a collective gasp of horror from the other customers of the coffeeshop.
You risk a look. Bald Guy has tucked the box under his arm and is fishing something out of his vest pocket. Brockner's face is a bloody, pulpy mess.
An impulse to do something grips you. What if you threw your laptop?


text:
Mobile App
Karmaveer Bhaurao Patil College of Engineering - KBPCE Satara - KBPCE
Karmaveer Bhaurao Patil College of Engineering , Satara is one of the esteemed educational institutions in the state of Maharashtra. The college was established in year 1983 and has continued its prestigious journey for the last 30 years. It is affiliated to Shivaji University situated in the district of Kolhapur and comes under the approval of AICTE, New Delhi.Mission of KBPCE is 'to foster critical analysis by training students both in theory and practice so as to equip them with skills needed for facing global challenges with team work and human values. And to build quality network with the Industry, educationists and the society for exchanging knowledge'. The modern teaching methodology assists the students in getting an all around view of engineering, technology and the entrepreneur world. The diligent faculty team of the college possesses hands-on experience and up to date knowledge of their subject and area of expertise. The infrastructure and facilities of KBPCE consists of spread-out campus alongside various amenities in the form of library, computer center, classrooms with proper teaching and learning aids, medical facilities etc. The institute seeks to place each of its students in an organization/company of great repute.Mission is to achieve the status of frontline technical institute in the state of Maharashtra.To achieve academic Autonomy
Overview Courses
|List of entrance exams
|Percentage students passed first class
|Percentage students passed with distinction
|Total faculty
Overview Placement
The Training and placement Cell constitutes of Training and Placement Officer as a head and the Departmental Training and Placement officers as coordinators for each department. Training and Placement coordinator coordinates training session for each class in two hours a week, which is included in academic timetable. Department Coordinator also maintains student data of the department and helps TPO in campus recruitment drive process.
|Number of visiting companies
|Average Salary
|2.1 lacs
Overview 360° View
|Last Update
|02 Apr, 2016
|Many awards has been given to the institute and respective students.


text:
now itMature
I was happy. But the room was getting crowded and boring, like always lol. "Hey, I'm going to go walk the sand," I told my cousin, Alyssa. She nodded, my keeper apparently, and continued talking with Abby, one of my many other cousins.
I saw Solomon, my brother, and my dad arm wrestling. Solomon won, obviously. "Solomon, you're such a beast!" Abby exclaimed, because that was his nickname. Alex laughed and slapped him a high five, asking for a turn. 'To fail,' I thought.
I opened the screen door, and smiled when the white frame creaked, it always had. Everything about this was my home, were my longings. Well, sort of; this was my grandmother's yacht stationed on the coast of Myrtle Beach.
I walked my leisurely pace up the dock and down to the shop-side beach. This vacation was awesome, but it was more like a reunion because everyone somehow related to me was here. I wasn't complaining though, Abby had brought her oh-so-hot boyfriend, Foster Carney, along with Alex, his funny, spontaneous brother.
I took my time, we were docking off late in the afternoon to see the sunset and go snorkeling. I was really looking forward to seeing just how ripped Foster was.
People wearing large floppy hats occasionally passed me with dripping ice creams. I'd get to the side and smile and they'd sometimes smile uncertainly back. My grandparents had finally carried out on their dream to move to the beach. So here we were because the beach is so popular, and because my grandfather's a fish-fanatic.
I nodded to the saxophone guy that played every evening under the night lights.
I always loved to watch him feed the gulls. He stayed so still in the day that birds perched up on his arms and people jumped when he moved because they thought he was a statue like the ones around him in the park.
When he saw me, he started walking and we met in the middle by the fountain.
I sat down beside him on a brick wall and he picked up his instrument and started playing.
It was then that I started wondering just what it was that made something yours. My family belonged to me by blood, something that could never be broken, I knew.
I guess I was wrong, blood tythes can be broken, by death. The most unsettling thing to me now, is to have something you know, be changed. I hate change, that's something that won't ever change. Because I always have and always will, even death can't rob me of that trait.
A bad omen? I looked at him; he never played at this time. Such melancholy notes made their way out into the open streets, I stared out, charmed, into nothing. It was as if giving he was giving me sympathy, I thought idly. As if I needed it, he was the street player one.
Another question popped into my head, what decided the need for sympathy? What quality of life made one pity?
Dang! I thought, I'm on a role with all this philosophy stuff!
I wondered about that, and how long I'd been here too. But that was just a flame of my mind's fire of contemplation. Strange, usually when time felt this stretched Alyssa would come yell for me and we'd race along the sand until one of us slipped on the fine grains. It was almost always her, because, I'm the athletic one.
When the sun started reaching for the horizon, I started jogging back to the dock. I was so far away from it, less than a mile but I could see it as clear as day. I reeled at the grief I was going to get, and how far I had walked unconsciously.
The ocean was thrashing as if hell were upon it. Then I saw what the boat was doing. It boat was floating out into the ocean. Then it was track meet and I was that crazy Jamaican dude in the 2008 Olympics.
I was conscious of the blood pumping loudly through my ears, adrenaline coursing threw my veins, making every sound crystal clear, and my vision etched sharp.
Then I heard the screaming and I wondered where it was coming from. I swung my head every way, panting, the yelling suddenly silent. No one was coming out of their houses, peeking through their windows, or least of all, screaming.
If anything, it seemed like this part of the deserted beach was just that, completely deserted.
It was me and the world was deprived of sound. I was the only human for miles I think. Grrr, where was everyone? "Help! Yo!" I yelled. But no one was around; the streets had been deserted as quickly as the tide comes in. Gradually, unnoticed and routine.
By the time I got to the dock, the boat had become blurry against the fading horizon and the sea had become angry. Why had no one noticed this, I thought, they can't be that into conversation to not notice that they're floating away into dangerous waters.
The boat blew up, firing bits of material everywhere out into the ocean. Smoke rose endlessly into the bloody sky, a great mass of fire burning under the black.
It took me about five minutes to process what I had heard and was seeing, as others would've reacted instantly. God help them! I thought, partly dumb-founded.
But what else could I do? The other option would be to lose it right then and there, which knew I was close to doing anyway.
I was pitiful, helpless. My family could be dying and I didn't know how to swim. I should've taken Mom up on those lessons damn it! Suddenly I couldn't hear and I staggered back as sound left me in a rush. I fell backwards to the dusty wood beneath my feet.
I will hope, I told myself relentlessly. It's all I have left. All I have left, alone....
Something then wrenched inside me, tearing what was left of me apart, leaving nothing. Sadness stronger than love overcame me and my head fell back, my body going completely limp. I hated something, but I didn't quite know what at the moment.
That's when I understood, one thing at least that I knew. If my family were ok, I wouldn't feel like this, I would know, somehow.
My mind grappled with this theory, like the angel and the devil on my shoulders, there were two sides to the war raging inside my head like a storm cloud.
You're over-reacttin, they will be ok....Why are you kidding yourself you weak little bitch! Only a coward dedicated to love would think that....
It was something we never realized, once you were happy within others, love had the power to destroy you. And I don't mean kill you, but a fate worse than death I now know. A destany to be forever in pain and guilt and sorrow. It could make you brake or shun people, your choice.
My fingers grabbed at my ears, trying to open up my hearing again. After a couple seconds, I became aware of a sticky liquid dripping down from above my eyes. Blood.
I didn't dare touch the wound to make it worse, that was probably a really stupid assumption though, and my vision got really blurry.
It was all disorienting after the hyper-aware senses the adrenaline had given me.
I licked my lips to find the saltiness of ghostly tears silently stealing their way down my face that was now too pale.
Why was I crying again?
Was I dead? No, I was still breathing. I listened to the sound of my breathing, in, out. While I cried I wondered what was so important about death that two opposites like fire and water would work together to create such ugly sorrow.
I had thought the elements were supposed to be spiritual, not hateful. Too many opposites ran in endless circles around in my skull.
Then I realized that I didn't hear a pulse. That familiar sound of the heart beating was gone. I stood up as hearing came back to me slowly.
Without, a pulse, without a heart....my family I loved, they were my heart....gone....the only living beings without hearts were demons, Alyssa said. Beings without love, no good....
I saw the flashing lights before I heard the sirens. The trucks got there and immediately did their job. No one came to me for several minutes. I didn't notice them hardly, and they most certainly did not care about me.
Nice timing, I thought bitterly. Come after there's no hope.
I looked over the dock and spit; it was scarlet. Blood, and I hadn't even realized it. I had bit my lip too far. Pain became shockingly aware in my body.
I ached all over, especially my head, I tried to release my lip, but my teeth wouldn't let go. So I stood there, letting my blood drip back into the earth.
However I did notice when I was grabbed and put forcibly into a police.
I don't know how long I screamed and struggled until they knocked me out.
Pitiful really.


text:
Monday 8 March 1965
It was Monday, under the sign of Pisces. The US president was Lyndon B. Johnson (Democratic). In that special week of March people in US were listening to Eight Days A Week by The Beatles.
In UK It's Not Unusual by Tom Jones was in the top 5 hits.
The Train, directed by John Frankenheimer, was one of the most viewed movies released in 1965
while Funeral In Berlin by Len Deighton was one of the best selling books.
But much more happened that day: find out below..
Or have a look at the whole 1965.
Old Newspapers
Have a look at the old newspapers from 8 March 1965 and get them!
Which were the most popular movies released in the last 30 days ?
TV Series
Which were the most popular TV series released in the last months ?
Find out your future
Get a FREE Numerology report based on the digits of 8 March 1965!
Wish him/her..
Historical Events
Which were the important events of 8 March 1965 ?
- Saint Philemon (d. 305)
- Albania, Romania - Mother's Day.
- Catholicism Saint John of God.
- Hudson's Birthday - The Second Coming Of Christmas.
- Saint Humfried of Terwaan
- Saint Cyrillus of Africa
Famous Birthdays:
- Fatima Lopes: Portuguese fashion designer.
- Kenny Smith: NBA guard (Houston Rockets).
- Fátima Lopes: Portuguese fashion designer.
Famous Deaths:
- Esther Howard: Actress (Detour), dies of heart attack at 72.
- 1st US combat forces arrive in Vietnam (3,500 Marines)
- First US combat forces arrive in South Vietnam (3,500 Marines).
Music Charts
Which were the top hits in that special week of March 1965 ?
Top #10 songs in the USA
- The Beatles - Eight Days A Week
- The Temptations - My Girl
- The Supremes - Stop! In The Name Of Love
- Gary Lewis and the Playboys - This Diamond Ring
- Jewel Akens - The Birds And The Bees
- Roger Miller - King Of The Road
- Gerry and the Pacemakers - Ferry Across The Mersey
- Herman's Hermits - Can't You Hear My Heartbeat
- The Kingsmen - The Jolly Green Giant
- Little Anthony and the Imperials - Hurt So Bad
Search For Your Ancestors
Subscribe to our Newsletter
Don't miss our monthly news, no spam guarantee Click here to Subscribe
...and if 8 March 1965 was your Birth Date then Join our Birthday Club!
Make this date unforgettable
CD and DVD Birthday Cards
Magazine Covers
What news were making the headlines those days in March 1965?
- SportsIllustrated: Sports Illustrated: no.7912
- Life: Death of Malcolm X
- Time: TIME Magazine Cover: Jeanne Moreau -- Mar. 5, 1965
Which were the most popular books released in the last weeks ?


text:
Invisible Part 1
Book by: swillfreat
Status: Finished
Genre: Action and Adventure
Chapter1 (v.1) - Invisible Part 1
The boy was bored, he pulled out his agenda and wrote the title of the homework. The time was passing slowly. For him, one hour was like 5 days.
-Elwood, Elwood wake up, it's been five times I told you to leave the class! Elwood!
Elwood was his surname, his name was John.
He left the class. As he returned home, he said to his father:
Hi dad, how are y…….
With nothing more than one step around him, his father left the house. No, it was not a special day, it was just one of those days, he was "invisible" . That happens almost every day and everywhere. He still tries to make his father say "Hello''.
Because of the depression, he wasn't making his homework sometimes, but this time he did all the homework and even wrote a commentary for the story.
The next day, he sat, proud of himself and waited the teacher to get his homework. Unfortunately, the teacher passed him. First time! She ignored John.
That were the random days of John…
Wait, WHAT???
He was sitting on the front of a plane's control cabin. He was turning the wheel just like he does at Flight Simulator. But this was real. He felt the sense of panic. He stopped, dropped the wheel, then… the alarm, it activated itself. Afraid to crash the plane, John left his hands control the wheel. How, how is that possible? Without thinking, he landed the plane on St. John s' airport. He looked at the date, WHAT?-24 January, St.John's day.
John, at the St. John's airport at St. John's day. Strange…
Continues at: INVISIBLE part 2.
© Copyright 2017 swillfreat. All rights reserved.
Add Your Comments:
Other Content by swillfreat
Short Story / Mystery and Crime
Book / Thrillers
Short Story / Young Adult


text:
I was about to purchase an application (for $0.99) and wanted to bill it to the account rather than my credit card. My understanding was that billing to the account was something that could be done. Why is this option not showing up?
Solved! Go to Solution.
I understand not wanting to charge $0.99 to a credit card. Through Google you can bill to your Sprint account, but Apple you will not be able to. Below I have provided the steps for Google play.
I hope I was able to answer your question, and if you need anything else please let me know!
Sprint Social Care Team
Tuesday –Saturday 1-10pm mst.
This stopped working and now gives error message from your mobile service provider: Subs id not found root exception is securitymanagerservicerequest. GetCBIsubscriber INFO 755
What is going on?
This stopped working and now gives error message from your mobile service provider: Subs id not found root exception is securitymanagerservicerequest. GetCBIsubscriber INFO 755
What is going on?
I am trying to do the same thing, pay for googleapps on sprint account. I follow the instructions and get an error "your purchase on your Sprint USA billing account was declined". I have three phones on my plan all with different gmail addresses. The phone I am trying to download to is not the primary. Is that the problems and any suggestions to help. I looked for a setting on my Sprint online account to authorize to all 3 phones but did not see anything like tat.
Make sure you are not authenticating via the wireless and only the phone network. I found it has issues and when I shut off wireless and only allowed Sprint network to connect it worked. NOTE if you have an air rave you may still need to get away from it I have one and I needed to stay clear of it before it started to work.
Thank you! Your solution fixed the problem I was having with my downloads!
My wireless is off and it still says error. I waited weeks and it still says error. I've already called customer care, not much help there.
Thank you for the post. What phone do you have? What exact error message or code do you see on your end?
Social Care
Thank you for the update. Please do let us know if you have any questions.
Sprint Social Care Team
Find out whats happening on the bridge, we'll share new features and fun on the community as well as exciting news from the mothership...read more.


text:
× View Today's Deals
You missed it This great deal for Authentic Strength and Performance Institute is over. But don't despair, we've got more great deals every day.
Related Deals That You May Like
SMX Training
3 or 5 Personal Training Sessions
New Orleans$135$45
Exercise Science
5 Personal Training Sessions in New Orleans
New Orleans$200$78.99
Body by Jude 504 at 2nd to None Fitness
1-on-1 Personal Training Sessions
New Orleans$750$89.99
Kelly Personal Training
Three Personal Training Sessions
New Orleans$135$65
back by popular demand:
Authentic Strength and Performance Institute
One Month of Unlimited Fitness Classes
- Save 65%
- 14 purchased
deal over
deal over!
100% recommendedin LivingSocial customer ratings
Whether you're looking to beef up, slim down, or tone, you can do so at Authentic Strength and Performance Institute -- snag unlimited access to this private training center for max results:
• $35 ($100 value) for a month of unlimited fitness classes
• Signature classes include SmartFit, TRX, Body Weight Blast & more
• Metairie studio hosts classes Monday through Saturday
Authentic Strength and Performance Institute on Facebook
PAID VALUE EXPIRES ON May 25, 2022
PROMOTIONAL VALUE EXPIRES ON April 14, 2014


text:
You missed it This great deal for Opus Fine Dining & Wine Bar is over. But don't despair, we've got more great deals every day.
Related Deals That You May Like
back by popular demand:
Opus Fine Dining & Wine Bar
$25 of Creative Brunch or Lunch, or a Five-Course Seasonal Tasting Menu for Two in Cherry Creek
- Save 52%
- 114 purchased
90% recommendedin LivingSocial customer ratings
The food is not only the most noticeable highlight at this inspired eatery. From elegant ambiance to the flawless service, you're in for a memorable meal with this offer:
• $12 for $25 to spend on food and non-alcoholic drinks for brunch or lunch
• $79 ($158 value) for a five-course kitchen or vegetable tasting menu for two
• Lunch is served every day; Sunday brunch is available from 10 a.m. to 3 p.m.
"Consistently innovative and delicious, with a menu that changes seasonally... The pork chops were the most succulent and tasty ever, the crab cakes generously packed with crab and nicely pan-broiled with a delicate outside crumb. Salads have first-quality freshness." - Google Reviewer
Fancy Dining at its Finest
Swing by at brunch to fall for soufflé pancakes or a Spanish breakfast sandwich (with cured chorizo, fried egg, Manchego, and sweet quince paste); or, stop by during lunch for a pork belly sandwich with apples and a Dijon glaze or sea scallops with an olive tapenade vinaigrette. You can also opt to sample unique tasting menus featuring kitchen creations like a rib-eye with radishes and kimchi broth or raspberry crème brulee. The vegetable tasting menu offers insight into some of the freshest local produce of the season -- you could be crunching on warm spring peas in an orange brûlée, inhaling the fragrance of herbaceous charred green onion ravioli, or savoring every bite of a lemon tart with almonds.
PAID VALUE EXPIRES ON May 22, 2022
PROMOTIONAL VALUE EXPIRES ON June 5, 2014


text:
San Joaquin County Man Accused of Attempting to Assist Al-Qaida
A Federal complaint says 20-year-old Nicholas Teausant was actively searching to join an anti-American terrorist organization in Syria, known as ISIS, or the Islamic State of Iraq and Syria - commonly referred to as al Qaida in Iraq. The FBI got wind of Teausant's online activity last year, and a confidential informant often met with Teausant, gaining his trust.
Teausant expressed a desire to offer weapons training to ISIS members, and at one time planned to bomb the LA Metro train system. Teausant sold his laptop to an undercover FBI agent to help pay for his trip to Syria. The complaint says the computer contains searches for items like "how to build a bomb," and "where can I buy an ISIS flag."
Teausant was arrested Sunday in northern Washington state, while on a bus heading for the Canadian border. He appeared in a Seattle court this afternoon, and will return to Sacramento to face one charge of providing material support to a foreign terrorist organization.
In an interview, just days ago, Teausant expressed his views on a man's freedom of expression when the man - who is not military affiliated - wore military clothing at Delta College.


text:
You are currently using an unsupported web browser.
We support the latest versions of these browsers:
If you have any problems while attempting to download a browser, you should contact your organization's system administrator.
For any questions related to Cvent, feel free to contact our Customer Care team.
Marquis Hotel, a modern take on a Victorian seaside hotel in the heart of the English Riviera. An ideal place for families, business trips and overseas visitors. The Marquis Hotel has recently re-opened after extensive refurbishment and our aim is to provide you with both comfort and luxury in a be...
You must be logged in to view contact information for this supplier. Sign up for a free Cvent account today.


text:
How did you spend your last bonus? Mojitos.
Stephen Rowe
Firm: Mishcon de Reya
Position: BD and communications manager (real estate)
Lives: Clapham
What time do you start work each day?
I aim for 7am but I do seem to have quite bad luck with trains ….
What's the most boring thing you've been asked to do in your job?
Stuffing envelopes for an event. I'm sure there's a machine that can do it.
How much time do you spend on Facebook each week?
Around two hours. All outside of work time of course!
What is the most unusual Christmas present that you have received from a colleague?
A DVD of Legally Blonde 2. (Thanks, Fred.)
If you could introduce one law, what would it be and why?
Ban key public transport workers from striking.
How did you spend your last bonus?
What are the best perks of your role?
The social aspect – constantly meeting new and interesting people.
What do you wear on dress-down Fridays?
Law firms tend to stop dress-down Fridays just when I start or start them just as I leave. Maybe it's because they know I would wear my .
Have you ever been asked to do anything at work that you suspect might have been illegal?
I decided to get into law after reading John Grisham's The Firm but so far have been required to undertake no unlawful activities. You didn't of course ask what I've chosento do.
What is the most irritating habit of any partner you've worked for?
Printing off emails and sending back a written response through the internal post. Some more senior partners don't like computers.
Do you see your colleagues on weekends?
On occasion – but I quickly cross the road before they see me.
Have you ever fallen in love at work? (If so, please provide details).
The terms of my parole mean I can't talk about it.
If you were a lawyer what would your practice area be and why?
Real estate – it's fast-paced, connected and very sociable.
What do you eat for lunch?
It varies. The week after payday I eat Itsu sushi and drink Starbucks; the week before payday I make my own sandwiches and drink tap water.
Is your salary (in thousands) greater than your age?
Yes, although the fact that I'm barely out of my teens helps.
What items do you always carry around with you at work?
I always carry my door pass, BlackBerry, wallet, notebook and pen. Also my passport in case I have to flee the country.
Who do you have photos of on your desk?
That question should read: "Of whom do you have photos on your desk?" Maybe I've worked in a law firm for too long.
Corney & Barrow or The Royal Exchange?
How about La Lluvia de Oro in Havana ….
Soy Latte or Nescafe?
I don't drink coffee. But there aren't many things I wouldn't do for a grande skinny chai tea latte from Starbucks.
City break or weekend in the country?
I'm definitely a City boy. I think I may be nomophobic (self-diagnosed) and there are vast swathes of countryside that don't have mobile phone reception.
Sum up your firm in three words.
Innovative, receptive and supportive.


text:
Can't find the item you are looking for using the search and browse tools above? Click Here to view a wider selection that includes items we can special-order for you.
Inspired by the Dutch Stroopwafel, Honey Stinger's Organic Stinger Waffle will become your favorite ride food. They've sandwiched the great taste of honey between two thin waffles for a treat that's crunchy on the outside and thick and syrupy on the inside. Since good fuel equals good workouts, the Stinger Waffle uses honey as its main energy source. It's natural, easily digestible, and contains many vitamins, minerals and antioxidants.
• Price is for one waffle
• USDA certified organic
• 160 calories
(based on 1 review)
of respondents would recommend this to a friend.
Write a Review
Best Uses
Reviewed by 1 customers
Sort by
Displaying reviews 1
Very delicious!
By Cha Boi
from Danville, CA
About Me Avid Adventurer
Such a delicious snack, with a bunch of great flavors to choose from. Fun texture and awesome to pair with a cup of coffee. Sits flat in a jersey pocket.
Bottom Line Yes, I would recommend this to a friend
Was this review helpful? Yes / No
- You may also flag this review
Back to top
Previous | Next


text:
Gainesville Hotels with Free Wifi
Search for Free wifi hotels in Gainesville
Get Secret Prices on select hotels
These prices aren't available to everyone.
Deal of the day
See all 23 Gainesville deals
- University of Florida
- Shands at the University of Florida
- Ben Hill Griffin Stadium (The Swamp)
- Sante Fe College
- Gainesville Raceway
- Ginnie Springs
- North Florida Regional Medical Center
- Oaks Mall
- Kanapaha Botanical Gardens
- Camp Blanding Museum and Memorial Park
- Paynes Prairie Preserve State Park
- Devil's Den
- San Felasco Hammock Preserve
- Curtis M. Phillips Center
- O'Leno State Park
- Florida Museum of Natural History
- Ironwood Golf Course
Free Wifi in Gainesville
"Free wifi Hotels in Gainesville - Check, compare and book discounted Gainesville Free wifi hotels at Hotels.com. Using Hotels.com booking engine is easy, simply insert your travel dates and find a Free wifi Hotel in Gainesville or near Gainesville online.
Hotels.com always has the best selection on Free wifi hotels in Gainesville: view hotels by star rating, amenities, theme, location, neighborhood or brand
Search for the perfect Gainesville hotel with the lowest room rates and best amenities by reviewing hotel details, guest reviews, photos and more!
Booking your room online is secure and fast!
After you book, you will receive an email and text confirmations on the reservation details of your online hotel booking
Don't forget to sign up for the Hotels.com Welcome Rewards Program, it's free! – the membership Program offers you 1 free night* after you book 10".
Don't forget to sign up for the Hotels.com Welcome Rewards Program, it's free! – the membership Program offers you 1 free night* after you book 10".


text:
David Rosen
The Key Publishing House
c/o Planned Television Arts
1110 Second Avenue, New York, NY 10022
9780978252687, $35.95, www.plannedtvarts.com
Politicians are human and have all of the same human flaws. "Sex Scandal America: Politics & the Ritual of Public Shaming" goes over the history of the United States and its flawed politicians from even before the United States existed, with the not-so-pure Puritans. Over the years, sex scandles have changed from cause to hang someone to merely fodder for the likes of Jay Leno. "Sex Scandal America" is a spicy look about how scandals and American culture have changed over the years.
|Printer friendly Cite/link Email Feedback
|Title Annotation:
|Sex Scandal America: Politics and the Ritual of Public Shaming
|Small Press Bookwatch
|Article Type:
|Book review
|Sep 1, 2009
|Previous Article:
|Free Loader Directory.
|Next Article:
|Undaunted Heart.


text:
Surrey-based tax specialist Nicholas Acomb has helped launch a Scottish Amicable insurance policy designed to help parents pass on assets to children while providing for the growing need for expensive nursing home care.
Acomb, partner with Guildford and Farnham-based firm Stevens & Bolton, says people are increasingly hesitant to transfer assets to children because of fears over possible long-term nursing costs.
"It is important that solicitors know there is a product on the market dealing with nursing home care where it is a problem, when people are trying to give away assets in a tax efficient way," says Acomb.
"It is important then that they also get independent financial advice."
The policy uses a split benefit trust to create a tax-efficient way of providing for nursing home care and reducing inheritance tax bills on a person's estate. "It gets around the 'gifts with reservation of benefits' problem which occurs with inheritance tax legislation," says Acomb.
"A need was identified [by Scottish Amicable] to remove parents and children's worry of planning for future care and also reducing the impact of inheritance tax on death. We provided the legal input for a product that would satisfy this need."


text:
NRS Payette Short Sleeve Paddle Jacket
When the air is warm but the water's cold or the other way around the short sleeve NRS Payette Paddle Jacket is a convenient solution for staying comfortable. . Provides great splash protection without overheating. HyproTex 2.5 fabric is waterproof and breathable to keep you comfortable. Factory taped seams ensure waterproof performance. Rubberized latex free punch through cuffs and adjustable neck closure keep water out without compromising your comfort. Elastic drawcord with barrel lock seals the bottom of the jacket and prevents it from riding up while seated. Lightweight, pliable fabric easily packs into a dry bag so you can have it with you at all times.
|Regular Price
|Eastern Mountain Sports
Copy the following string into an e-mail to firstname.lastname@example.com to request support.
CCBot/2.0 (http://commoncrawl.org/faq/)
Blog Feed
Follow on Twitter
Become a Facebook Fan
Similar Gear


text:
It only takes a minute to get started. Fill out our uncomplicated sign up form and login to the website.
This step is noncompulsory but will dramatically multiply your chances of your profile being viewed by others. Write a little something about yourself, your hobbies and upload your nicest photo of yourself.
Utilise our website's state-of-the-art search to find over 60s members who match your criteria. Or just leaf through listings and find folks that you find attractive.
Identified someone who ticks all the boxes? Send a letter to them or just a wink and see what they say. With a little luck you'll be on your way to an amazing adventure.
It only takes a few minutes


text: SANDUSKY, Ohio, April 5, 2012 /PRNewswire/ -- Verizon Wireless today announced it is bringing the nation's largest 4G Long Term Evolution (LTE) network to Sandusky on April 19. With the 4G LTE network, customers can use 4G LTE wireless devices in Sandusky to access the Internet faster; listen to music or watch video on their phones; use thousands of apps; and stay in touch with family and friends, all with speeds up to 10 times faster than before. Verizon Wireless launched 4G LTE service at Cedar Point Amusement Park last year. When Verizon Wireless turns on its 4G LTE network in Sandusky, customers who live or visit areas including Danbury Township, Mineyahta-on-the-Bay, Sandusky Bay, Johnsons Island, NASA Plum Brook Station, and the towns of Grand Forest Beach and Castalia will also have access to the nation's fastest 4G network. "The future is here in Sandusky and it is Verizon Wireless 4G LTE," said Mark Frazier, president–Ohio/ Pennsylvania/West Virginia Region, Verizon Wireless. "Our commitment to 4G LTE is bringing customers a new level of wireless data service with upload and download speeds and connectivity that is revolutionizing the way we communicate." Since its launch on Dec. 5, 2010, Verizon Wireless has introduced its 4G LTE network to more than 200 million people in 203 markets across the country and supports more than 20 4G LTE devices, including a wide variety of tablets, smartphones, hotspots and more. In real-world, fully loaded network environments, Verizon Wireless 4G LTE customers should experience average data rates of 5 to 12 megabits per second (Mbps) on the downlink and 2 to 5 Mbps on the uplink.


text:
Bow and rosebud ring
58,00 €
Pearls, knots, gold and ties have been brought together to create a jewellery collection that symbolises the success of a happy union. The fine settings echo the gentle refinement of the materials. A timeless collection which creates a sentimental love story that is sure to stand the test of time.
Materials : Hand-enameled brass, freshwater pearls, rhinestones, beads
Dimension : 2cm
By buying this product you can collect up to 5 loyalty points. Your cart will total 5 points that can be converted into a voucher of 3,00 € (Usable on your next orders).


text:
things from begining to end about martin luther king jr.his real name was michael.place birth:atlanta,georgia,united sates.relegion:baptist.
Martin Luther King jr was born in january15,1929.
New node
the march on washington in August28 is whare MLKjr did his speach I Have A Dream avocating the racial harmony.
Freedom is never voluntarily given by the oppressor; it must be demanded by the oppressed.(A Qoute by martin luther king jr


text:
Golf Galaxy is your home for the hottest golf deals. Check out great savings on gear from top brands like TaylorMade®, Callaway®, Nike®, PING® and many more.
Save on everything you need for your next round, including:
- Golf Clubs: Get deals on men's, women's and kids' clubs that will get you from the tee to the green in fewer strokes. Shop drivers, fairway woods, iron sets, hybrids, wedges and putters, or get everything you need with a complete golf club set.
- Golf Balls: Check out great deals on golf balls from the best brands, including top-sellers from Titleist®, Top Flite®, Srixon®, Maxfli® and more. Stock up for your next round—you can never have too many.
- Golf Apparel: Save on great golf apparel, including form-flattering women's golf styles and great deals on men's golf clothing. Get everything you need to play in all conditions.
- Golf Shoes: Find deals on men's and women's golf shoes from FootJoy®, PUMA®, adidas® and ECCO®. Choose spikes for added traction or go with hybrids for off-the-course versatility. Don't forget to check out great savings on socks.
- Golf Bags & Carts: A golf bag is one of the most important investments you can make. It needs to be a highly functional bag that looks sharp on the course. At Golf Galaxy, you'll find great savings on cart bags, stand bags and carry bags, plus deals on travel bags and covers. Choose from multiple designs and colors.
- Golf Technology: Get an edge during your next round with great deals on the latest golf technology, including watches, GPS systems, rangefinders and more.


text:
Gujarat Public Service Commission (GPSC) has issued a recruitment notification for the recruitment of Additional District Health Officer through recruitment notification . Candidates who have completed MBBS, MD can apply for the new recruitment notification from Gujarat Public Service Commission (GPSC).
Eligible candidates can apply online for the Additional District Health Officer Job on or before 16/2/2016. Find more information about the vacancy like Age limit, Selection Process, Qualification, Application fee, How to apply etc can be found below.
Company Name : Gujarat Public Service Commission (GPSC)
Vacancy Name : Additional District Health Officer
Educational Qualification :M.B.B.S,MS/MD
Total No of Vacancy : 02 post
Salary : Rs. 15,600 – 39,100/-per month
Job Location : Gujarat
Last Date to Apply for this job : 16/2/2016
Address for the Job Vacancy : Gujarat Public Service Commission,Gujarat
Detail of Post :
Additional District Health Officer Job position in Gujarat Public Service Commission (GPSC)
Educational Qualification : Candidates must possess Degree in Medicine with PG in Preventive & Social Medicine or Sanitary Science or Community Medicine from a recognized University
No: of Posts : 02
Age : Candidates age must be maximum 40 years as on 23-10-2015
Pay Scale : Rs. 15,600 – 39,100/- + G.P Rs. 6,600/-
Selection Procedure :
Candidates can apply on or before 16/2/2016.
No detailed information about the selection procedure is mentioned in the recruitment notification.
How to apply ? :
Candidate Should apply Online latest by 16.02.2016
Important dates to remember :
Last Date to Apply for this job 16/2/2016


text:
Otherwise known as my fantasies.
"This will work. I promise," I reassure Betsy.
"I know, I know..I'm just..nervous," she's smiling halfheartedly, that I'm about to die in front of my parents I don't know what to do I'm freaking out but I'm trying to hide it smile. I take her hand, hoping to calm both of our rapidly beating hearts in the process. We walk inside.
I see that nothing is different. A huge entryway, a staircase 3 paces to my left, stairs leading down to a small unused family area.
"We're home!" calls Betsy, her voice shaking. Her parents walk in and hello's are exchanged. As they hug, not even noticing me at first, I see that both pairs of eyes are more sunken than before, and her father's hair is grey, her mother's white. They really are nice, I think to myself. Then they turn to me.
"Um..Betsy? Why is Rowan with you?" her mother says, still looking at me quizzically. I smile sweetly, trying to help as much as possible.
"Mum? Dad? We need to talk." Betsy leads the three of us into the kitchen. At the table, we sit across from her parents. I take her hand under the table and squeeze it. I catch her eye and try to tell her, just like we rehearsed, love. You can do this. I don't think she gets it. Her palms are sweaty and shaking. For some reason, I'm fine, just worried about her. Something about her being so nervous makese me calmer, like I need to be there to protect her.
"I know this is going to be hard for you to hear," Betsy begins, "But you need to listen to everything, EVERYTHING, before saying A WORD. Ok?"
"Ok," they said simultaneously.
"I'm in love."
She gives that piece time to sink in. I try to read her parent's expressions. They both seem excited, but more than that they seem relieved. Relieved?! That makes me beyond angry. But I hold my tongue, knowing that this is for Betsy, not for me.
"With a woman."
Shock. As I expected, this is the first thing I see. Then..I'm not sure anymore. Her mum looks like she's trying to suppress the mountain of emotions that are probably toppling over her. Her Dad looks like he just swallowed something rancid. Neither of them say anything. Good. This is going better than expected.
"I've waited 9 years to tell you this, ever since 7th grade when I came out to myself. But I knew that I needed to wait until after I got out of the house. I bided my time. Let you live your lives, while I lived my real life outside of the house. And in 7th grade I fell in love with a girl who I was surprised to find loved me back. Then she broke my heart then she mended it slowly over a period of 6 years. I haven't been able to tell you this because of how ignorant and conservative and close-minded you are, and I'm done with it. Right now you have to make a decision. Take me as I am, or tell me to leave and never come back. Stay or go. If you let me stay, know this: thank you. If you tell me to go, I will happily. It will not change my decision to move to New York City and be married to the lovely woman sitting next to me at this very moment." Betsy's face is red, she's shaking more than ever, and she looks like she's about to start bawling. But to me she looks strong, independent. Her short, shaggy brown hair hangs over her left eye, her eyes remind me of a puppy dog's eyes in the way that they melt me, and her style blows me away. I feel like I just walked out of a dumpster sitting next to her, yet here she is, telling her parents that she will marry me in NYC while at the same time indirectly saying yes to my proposal.
The 'yes' I've been waiting for for 6 years inspires my next comment.
"Mr. and Mrs. Snider?" I say, not knowing what else to call them, "I need to say something. I have been with your daughter for a very long time, and I've gotten to know the real her. I know the life that she's had to live at home, I know how sweet she is to you, to me, to everybody she meets. I know her. And you need to know something. I will to anything to be able to openly love your daughter. I can love her just as much as any boy could ever; more, actually. She is the best thing that has ever happened to me, and I hope she feels the same way about me as I do about her. If you take this away from us..you will lose a daughter. I want to spend the rest of my life with her. Please. Just..please." I notice that I've dropped Betsy's hand and I'm standing up...oops. I sit down and look at my toes, knowing that if I could blush I would.
A long pause. Maybe minutes, maybe hours. When you're nervous and embarassed time moves differently.
"Are..are you sure?" her mum's voice is hoarse, even though it's only been about 10 minutes.
Out of the corner of my eye, I watch Betsy nod. Great, I think, I've made her cry. Damn it.
"Then..I guess that's that," her dad says, "There's no changing you, Betsy. We may not agree with you, but we will never lose you over something like this. Stay. Please."
We hug. All of us. I notice that her parents still won't speak to me, but at least they hugged me. This is a start. And before I know it we're all crying, relating stories of the past and acting like..well, like a family.
Afterwards, when we get back to our small apartment, we sit down. I take her into my arms and tell her how proud I am of her.
"Me? What about you? Where did that come from?" She looks up at me.
"I..um..I'm not sure. I think it was long overdue though," I say, grinning.
"I have one badass fiance," now she's grinning.
I lean down and brush my lips gently against hers.
"Fiance..I like that."


text: Tis the season of the egg. Some might say Easter is the season of the egg, but deviled egg lovers know how guests at any gathering love to see a plate of deviled eggs enter the door. Every family has their own version of the classic deviled egg recipe which is usually the go to standard. But who doesn't love a little twist on the classic deviled egg? A quick tour of the wonderfully deviled … [Read more...]


text:
Who tracks their Focus and where do they do it?
View Single Post
Focus Rookie
Join Date: Oct 2007
Fan#: 51277
Location: Central Ohio, OH
What I Drive: 2002 Sonic Blue SVT
Posts: 8
FF Reputation:
Buy-Sell-Trade Rating: (
I am also in the Ohio/IN region. I have been running HPDE's for 4 years. Mid Ohio, Putnam Park, Nelson Ledges, BeaveRun. This year I took the plung and got the NASA competition/regional licence and rented a Spec Focus from Leo Capaldi Racing for the August NASA event at Mid Ohio. Three of us competed in the class that weekend. Matt, Craig C. and Me.
We had a great time, especially passing the slower Spec Miata's.
Then I rented again for the NASA National Championship races at Mid Ohio in September. More....lots of......bunches of fun.
Spec Focus is the way to go if....you got one...are too big for a spec miata,...want a fun car to race....close competition.....all the above.
All of us track dogs with Foci should really look into racing the Spec Focus series. For car prep the safety things would come first, roll cage, electrical shut off, fire extinguisher, seat belts. stuff you need to get on the track.
The performance stuff is what you do over the first few seasons as funds allow. You might not be the fastest car the first year but you will have a smile on your face. When the cars are rolling to the starters stand, all eyes are glued in the distance looking for a sign of moving green, then the engines roar and thirty or more cars are trying to get into the same corner and all jammed up. Now that is exciting fun stuff . Man I'm needing a fix right now.
View Public Profile
View Gallery Images
Find More Posts by NASAspecfocus2


text:
Dhaka University Journal of Pharmaceutical Sciences http://banglajol.info/bd/index.php/JPharma Full text articles available Dhaka University en-US Dhaka University Journal of Pharmaceutical Sciences 1816-1820 Three New Flavonoid Glycosides from the Fruits of Luffa echinata Roxb.- a Hepatoprotective Plant http://banglajol.info/bd/index.php/JPharma/article/view/30924
Phytochemical investigation of bioactive polar extracts of Luffa echinata Roxb. fruits led to the isolation and characterization of three new flavone glycosides viz., 3,5,7,3′,4′-pentahydroxyflavone-3-[-O-β-Dglucopyranosyl- 7-O-β-D-glucopyranoside (1),3,5,7-trihydroxy-(7′,8′- dioxo,9′,10′,-dihydro[a]cyclohex Δ13′,(14′), Δ11′(12')-12′,13′,-dimethyl)-flavone-7-[-O-β-D-galactopyranosyl-(1→2)]-O-β-D-glucopyranoside (2), and 5,7,8,4′- tetrahydroxy flavone-7-[-O-β-D-xylosyl-(1→2)]-O-β-D-glucopyranoside (3). The structures of the newly isolated compounds were elucidated on the basis of spectral data and chemical evidences.The isolated compounds are found to be new analogs of tricetin, quercetin and isoscutellarin.

Dhaka Univ. J. Pharm. Sci. 15(2): 117-125, 2016 (December)
 Tanveer Alam Ahmed Sulaeman Al Harrasi Bahar Ahmed Lubna Najam Shah Alam Khan Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 117 125 10.3329/dujps.v15i2.30924 In vitro Toxicity Study of Reconstituted Amphotericin B - Lipid Derivatives Dry Powder for Nebulization http://banglajol.info/bd/index.php/JPharma/article/view/30925
The aim of the present research work was to evaluate the safety of reconstituted dry powder amphotericin B (AmB) inhalation via nebulizer. This study was carried out on respiratory cell lines (A549, Calu-3, NR 8383), kidney cells (293T/17), human red blood cells (RBC) and aerosol properties were determined by Andersen Cascade Impactor (ACI). AmB, a lipid derivative reconstituted dry powder was formulated by lyophilization and reconstituted into distilled water at AmB concentration at 4 mg/ml. The value of MMAD, FPF were obtained as 1.7 to 2.05 μm and 70 to 80%, respectively. The cytotoxicity test carried out by MTT assay of lipid formulations revealed a very low toxicity on respiratory cell lines such as kidney cells, than pure AmB at concentration 1 to 8 μg/ml of AmB. In-vitro cytotoxicity results showed less toxicity to human red blood cells (RBC) than pure AmB at concentration 1 to 8 μg/ml of AmB.

Dhaka Univ. J. Pharm. Sci. 15(2): 127-134, 2016 (December)
 Kajiram Adhikari Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 127 134 10.3329/dujps.v15i2.30925 Partial Purification of Alkaline Protease as Thrombolytic Agent from Mutant Strain Bacillus licheniformis EMS250-O-1 http://banglajol.info/bd/index.php/JPharma/article/view/30926
Thrombosis leads to myocardial infarction, stroke and other cardiovascular complications. Microbial thrombolytic agents such as urokinase, streptokinase etc. are used to treat complications related to thrombosis. To search for new microbial enzymes as thrombolytics having better efficacy and specificity, Bacillus licheniformis EMS-O-1 mutant strain was cultured in modified urea-molasses media followed by purification using ammonium sulphate precipitation and ultrafiltration through centricon tube of 100 MWCO value. The yield of crude enzyme was 11129.14 U/mg and after purification 40180.46 U/mg. Purification process increased the specific activity of purified enzyme to 12.28 fold with a recovery of 17.79%. The purified enzyme was a serine protease with molecular weight of 25.5 kDa as confirmed by irreversible inhibition of activity with phenylmethylsulfonyl fluoride (PMSF) followed by SDS-PAGE gel image and by LC-MS analyses. In vitro clot lysis assay of the purified enzyme exhibited 38.30% thrombolytic activity. The crude enzymes from the mutant strain EMS-O-1 were found to be stable up to 50oC and showed maximum stability between pH range 7.5 to 8.5. These findings signify that proteases produced by B. licheniformis mutant have the potential to be developed as a viable thrombolytic agent.

Dhaka Univ. J. Pharm. Sci. 15(2): 135-141, 2016 (December)
 Md Asad uz Zaman Md Arafat Al Mamun Shakila Nargis Khan Md Mozammel Hoq Md Abdul Mazid Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 135 141 10.3329/dujps.v15i2.30926 Hibiscus sabdariffa Mucilage as a Disintegrant in Formulating Fast Dissolving Tablets http://banglajol.info/bd/index.php/JPharma/article/view/30927
The aim of the present work was to prepare and evaluate fast dissolving tablets of nebivolol with a view to enhance patient compliance and minimize the side effects. In this study, fast dissolving tablets of nebivolol were formulated by direct compression method using mucilages of tapioca seeds (Manihot esculenta), basella climb (Basella alba), red sorrel (Hibiscus sabdariffa) as natural disintegrants and crosspovidone as a synthetic superdisintegrant in different ratios with directly compressible mannitol (Pearlitol SD 200) as a diluent to enhance the mouth feel. The prepared formulations were evaluated for hardness, friability, drug content, in vitro dispersion time, wetting time, water absorption ratio, in vitro drug release, stability and excipients interaction. Among all the formulations, the formulation (FHD3) containing 8% w/w mucilage of Hibiscus sabdariffa was the overall best formulation (t50% 1.7 min) based on in vitro drug release studies. Stability studies on the formulations indicated that there are no significant changes in drug content and in vitro dispersion time (p<0.05). From the above studies, it can be concluded that fast dissolving tablets of nebivolol can be prepared using different mucilages as natural disintegrants for faster dispersion and disintegration in the mouth.

Dhaka Univ. J. Pharm. Sci. 15(2): 143-149, 2016 (December)
 SB Shirsand - Shivanand - Shailashri GG Keshavshetti V Jonathan Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 143 149 10.3329/dujps.v15i2.30927 Phytochemical and Biological Investigations of Eurya acuminata (Theaceae) http://banglajol.info/bd/index.php/JPharma/article/view/30928
The methanol extract of the powdered leaf of Eurya acuminata was investigated for isolation of secondary metabolites and two compounds were obtained by using VLC, column chromatography and TLC. The compounds were identified as phytol (1) and β-sitosterol by extensive spectroscopic studies, including high field NMR analyses as well as co-TLC with authentic samples. The methanol extract of leaf of E. acuminata and its organic and aqueous soluble partitioning materials were evaluated for cytotoxic, thrombolytic and antimicrobial properties. In the cytotoxicity study the aqueous fraction of crude methanolic extract showed significant lethality towards brine shrimp having LC50 value 8.821 μg/ml as compared to standard vincristine sulfate (0.404 μg/ml). In the study for thrombolytic property, different extract of E. acuminata exhibited various thrombolytic activity ranging from 13.66 to 31.89 % as compared to standard streptokinase (46.51 %). No antimicrobial activity was observed from leaf extracts.

Dhaka Univ. J. Pharm. Sci. 15(2): 151-154, 2016 (December)
 Tahmid Faisal Monira Ahsan Jakir Ahmed Choudhury ATM Zafrul Azam Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 151 154 10.3329/dujps.v15i2.30928 7-Methoxy-8-Prenylated Coumarins from Murraya koenigii (Linn.) Spreng. http://banglajol.info/bd/index.php/JPharma/article/view/30930
Four coumarin derivatives were isolated from the methanol extract of stem bark of Murraya koenigii (Linn.) Spreng. Extensive spectroscopic studies, including high field NMR analyses allowed to identify these compounds as meranzin hydrate (1), epoxyosthol (2), isomeranzin (3) and murracarpin (4). The identity of the compounds was confirmed by comparison with published data as well as co-TLC with authentic samples. This is the first report of occurrence of meranzin hydrate (1), epoxyosthol (2) and isomeranzin (3) from M. koenigii.

Dhaka Univ. J. Pharm. Sci. 15(2): 155-159, 2016 (December)
 Md Mubarak Hossain Faiza Tahia Md Abdullah Al Mansur Mohammad A Rashid Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 155 159 10.3329/dujps.v15i2.30930 Estimation of Loss of Iodine from Edible Iodized Salt During Cooking of Various Bangladeshi Food Preparations http://banglajol.info/bd/index.php/JPharma/article/view/30931
Iodine is one of the essential micronutrients required for the normal mental and physical development of human beings. Low iodine intake exerts several detrimental effects on human health. The most serious effect of iodine deficiency is represented by possible damage to the fetus such as stillbirths, abortions and congenital abnormalities. According to the existing law, iodized salt should contain at least 15 ppm of iodine. However, iodine is lost significantly during cooking and few studies have been conducted to estimate such loss of iodine. Hence, in the present study, thirty recipes commonly cooked in Bangladeshi families were taken and by using colorimetric assay method, it was found that the mean losses of iodine during different cooking procedures were 13.28% for pressure cooking, 23.46% for boiling, 9.5% for deep frying and 5.18% for shallow frying. The results showed that the loss of iodine depends upon the type of cooking procedures and cooking time.

Dhaka Univ. J. Pharm. Sci. 15(2): 161-165, 2016 (December)
 KM Yasif Kayes Sikdar Amlan Ganguly ASM Monjur Al Hossain ABM Faroque Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 161 165 10.3329/dujps.v15i2.30931 Novel Co-processed Spray Dried Super Disintegrants Designing of Fast Dissolving Tablets Using http://banglajol.info/bd/index.php/JPharma/article/view/30933
In the present study, novel co-processed superdisintegrants were developed by spray drying method using microcrystalline cellulose and mannitol in different ratios (1:1, 1:2 and 1:3) for use in the fast dissolving tablet formulations. The developed excipients were evaluated for angle of repose, Carr's index and Hausner's ratio in comparison with physical mixture of superdisintegrants. The angle of repose of the developed excipients was found to be < 30o, Carr's index in the range of 9-15 % and Hausner's ratio in the range of 1.12-1.16. Fast dissolving tablets of glibenclamide were prepared using the above co-processed superdisintegrants and evaluated for pre-compression and post-compression parameters. Based on in vitro dispersion time (approximately 22.23 sec), promising formulation MCM3 was tested for in vitro drug release pattern in pH 6.8 phosphate buffer and stability (at 400C/75 % RH for 3 months), drug excipients interaction (IR spectroscopy) were studied. Among the designed formulations, the formulation (MCM3) containing 8 % w/w of co-processed superdisintegrant (1:3 mixture of microcrystalline cellulose and mannitol) emerged as the overall best formulation (t50% 1.6 min) based on drug release characteristics in pH 6.8 phosphate buffer compared to commercial conventional tablet formulation (t50% 6 min). Stability studies on promising formulation indicated that there were no significant changes in drug content and in vitro dispersion time (p<0.05).

Dhaka Univ. J. Pharm. Sci. 15(2): 167-172, 2016 (December)
 SB Shirsand RT Gumate V Jonathan - Shailashri Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 167 172 10.3329/dujps.v15i2.30933 Bioactivities and Chemical Profiling of Sesbania grandiflora (L.) Poir. Leaves Growing in Bangladesh http://banglajol.info/bd/index.php/JPharma/article/view/30932
The ethanolic extract of leaves of Sesbania grandiflora and their organic and aqueous soluble partitioning substances were evaluated for thrombolytic and membrane stabilizing potentials in vitro. In thrombolytic assay, among all partitionates, the ethyl acetate soluble fraction showed highest percent of clot lysis (59.57%) as compared to 69.23% and 3.07% exhibited by the standard streptokinase and water (negative control), respectively. With respect to the membrane stabilizing activity, ethyl acetate soluble fractions of S. grandiflora also profoundly inhibited the hemolysis of erythrocytes induced by osmosis (64.30 ± 0.64%) and heat (57.21 ± 0.69%), respectively. In contrast, standard acetyl salicylic acid resulted in 70.12 ± 26% inhibition of osmotically-induced hemolysis and slightly higher level of protection against heat-induced hemolysis (73.90 ± 0.29%). The ethanol extract of leaves of S. grandiflora revealed significant percentage of thrombolytic and membrane stabilizing activities.

Dhaka Univ. J. Pharm. Sci. 15(2): 173-176, 2016 (December)
 Farhina Rahman Laboni Samira Karim Jalal Uddin Zubair Khalid Labu Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 173 176 10.3329/dujps.v15i2.30932 Formulation and In vitro Characterization of Phenytoin Loaded Mucoadhesive Biofilms of Colocasia esculenta for Translabial Drug Delivery System http://banglajol.info/bd/index.php/JPharma/article/view/30935
The aim of our research work was to isolate a biomaterial from Colocasia. esculenta and prepare phenytoin loaded mucoadhesive biofilms using this biomaterial. The biomaterial was isolated from C. esculenta tubers by an economical process. The isolated biomaterial was subjected to various physical evaluation, chemical tests as well as spectral analysis. The drug-biomaterial interaction study was performed to see if there was any interaction of biomaterial with phenytoin. Phenytoin loaded biofilms were prepared using biomaterial, flexicizer and other co- processing agents. The prepared biofilms were evaluated for physical appearance, weight, thickness, folding endurance, swelling index, surface pH, tensile strength, percent elongation, percent moisture uptake, percent moisture loss, vapor transmission rate and content uniformity. The mucoadhesivity of biofilms was investigated using rotating basket method. The in-vitro drug release study of biofilms was performed on static MS diffusion apparatus. The stability studies of biofilms were carried out at different conditions of temperature and relative humidity. The results were compared with the standard hydroxy propyl methyl cellulose (HPMC) and sodium carboxymethyl cellulose (Sodium CMC) films. The experimental results revealed that the phenytoin loaded biofilms of C. esculenta possessed excellent mucoadhesivity, sufficient stability as well as appreciable release characteristics. The best biofilm formulation was PK6 with a cumulative drug release of 95.35 % over 36 hours. Hence, C. esculenta biomaterial can serve as a potential film forming agent for transmucosal drug delivery systems.

Dhaka Univ. J. Pharm. Sci. 15(2): 177-186, 2016 (December)
 Abhijeet Ojha NV Satheesh Madhav Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 177 186 10.3329/dujps.v15i2.30935 Investigation of Formaldehyde Content in Dairy Products Available in Bangladesh by a Validated High Performance Liquid Chromatographic Method http://banglajol.info/bd/index.php/JPharma/article/view/30936
Highly nutritious dairy products are ingested regularly by all ages of population. Adulteration of dairy products to enhance the inherent stability and acceptability to common consumers by different harmful and toxic ingredients like formalin, an unpermitted preservative, has been a burning issue in Bangladesh over the last few years. The aim of this paper was to analyze the concentration of formaldehyde in dairy products most commonly sold in Bangladeshi markets by a validated reversed phase high performance liquid chromatographic (RP-HPLC) method to reveal the on-going alarming scenario in a scientific way. After pre-derivatization with 2,4- dinitrophenylhydrazine, formaldehyde was detected at 345 nm using a C18 column with acetonitrile and water (45:55) as mobile phase at a flow rate of 2.0ml/min. The validated method has been applied to 41 marketed dairy products, including pasteurized milk, UHT milk, banana- mango- and chocolate-milk, flavored yoghurt, lassi, buttermilk, and skimmed milk. However, no formaldehyde was detected among the tested dairy products.

Dhaka Univ. J. Pharm. Sci. 15(2): 187-194, 2016 (December)
 Md Shahadat Hossain Md Samiul Islam Subrata Bhadra Abu Shara Shamsur Rouf Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 187 194 10.3329/dujps.v15i2.30936 Enhancement of Dissolution Profile of Poorly Water Soluble Loratadine by Solid Dispersion Technique http://banglajol.info/bd/index.php/JPharma/article/view/30937
This study was carried out to improve the dissolution properties of loratadine by solid dispersion technique. A series of solid dispersions of loratadine in PVP K-30 (1:1, 1:3 and 1:5) were prepared by kneading technique. The prepared solid dispersions were characterized by various physicochemical properties (fourier transform infrared spectroscopy, X-ray diffraction and scanning electron microscopy) and the dissolution characteristics were compared with loratadine and the physical mixtures of loratadine. It was revealed from the physicochemical analyses that there was a good compatibility between drug and carrier. On the other hand, the drug release from the prepared binary solid dispersions was significantly enhanced in comparison to both drug alone and the physical mixtures. Finally solid dispersion of loratadine: PVP K-30 prepared as 1:5 ratio was found to be described by non-Fickian release mechanism and was selected as the best formulation in this study.

Dhaka Univ. J. Pharm. Sci. 15(2): 195-201, 2016 (December)
 Md Zahir Uddin Jakir Ahmed Chowdhury Ikramul Hasan Md Selim Reza Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 195 201 10.3329/dujps.v15i2.30937 Formulation and In vitro Evaluation of Oral Floating Tablets of Salbutamol Sulphate: Comparison with Effervescent Tablets http://banglajol.info/bd/index.php/JPharma/article/view/30938
The aim of this research was to develop and evaluate gastric floating tablets of salbutamol sulphate. The oral delivery of anti-asthmatic salbutamol sulphate tablets were facilitated by preparing floating dosage form which could increase its absorption in the stomach by increasing the gastric residence time of the drug. Floating tablets were formulated by using different polymers like carbopol, xanthan gum, HPMC-K4 MCR and HPMC- K100 MCR with different proportions. A comparative study of normal effervescent tablets of salbutamol sulphate had also been done. The prepared tablets were evaluated for all their physicochemical properties and in vitro buoyancy study. In vitro dissolution studies of the formulations were done in pH 6.8 phosphate buffer using USP apparatus 2 (paddle method) at 50 rpm. Percent drug release of the formulations (F-1 to F-11) was from 87.34%- 99.12% after 12 hours. From the results, F-11 was selected as an optimized formulation based on 12 h drug release which showed minimal floating lag time and maximum floating time. On the other hand, 100% drug was released within 2 hours from the F-12 of effervescent salbutamol sulphate tablets in which polymer was absent while gas generating sodium bicarbonate and citric acid were present. The results of the study were consistent and may encourage formulating similar dosage form with other drugs.

Dhaka Univ. J. Pharm. Sci. 15(2): 203-208, 2016 (December)
 Md Haider Ali Mohiuddin Ahmed Bhuiyan Md Selim Reza Samira Karim Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 203 208 10.3329/dujps.v15i2.30938 Antibiotic Resistance, Plasmids and Integron Profile of Salmonella Species Isolated from Poultry Farm and Patients http://banglajol.info/bd/index.php/JPharma/article/view/30939
A total of ten selected strains of Salmonella species, five from the environment of poultry farm and five from patients were included in this study. All strains were isolated and identified by using selective media, standard biochemical and serological tests. Antimicrobial susceptibility tests were performed by disc diffusion method using twelve commercial antibiotic discs of aztreonam, ceftriaxone, kanamycin, ciprofloxacin, gentamycin, chloramphenicol, ampicillin, erythromycin, cephalexin, tetracycline, cotrimoxazole and nalidixic acid. Plasmid profile and integron gene detection were conducted by Kado-Liu method and PCR, respectively. Only aztreonam, ceftriaxone, kanamycin and gentamycin were shown to be inhibitory to all strains. However, ciprofloxacin, chloramphenicol, amoxicilin, erythromycin, cephalexin, tetracycline, cotrimoxazole and nalidixic acid revealed different degrees of resistance pattern against environmental and clinical strains. Analysis of plasmid demonstrated that three environmental strains contained both plasmids of 140 Mda and 62 Mda. On the other hand, another three strains, one environmental and two clinical isolate only contained 140 Mda plasmid. All the plasmid containing strains (140 Mda and 62 Mda) exhibited same type of drug resistance pattern, whereas strains containing the 140 Mda plasmid only did not show similar type of resistance pattern. Therefore, no correlation was found between plasmid containing strains and drug resistance. Four environmental strains were also found to be positive for the class I integron and one clinical isolated was positive for class I integron gene conferring resistance to common antibiotics. However, none of the strains were found to contain class II integron. Therefore, the present study demonstrated that both environmental and clinical strains contain both large to middle size plasmids and integron I but not integron II. The plasmid and integron I containing strains experienced resistance to different antibiotics, used in the experiments.

Dhaka Univ. J. Pharm. Sci. 15(2): 209-214, 2016 (December)
 Kohinur Begum Sultana Juhara Mannan Aliza Ahmed Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 209 214 10.3329/dujps.v15i2.30939 Effect of Serum Trace Elements, Macro-minerals and Antioxidants in Acne Vulgaris Patients: A Case-Control Study http://banglajol.info/bd/index.php/JPharma/article/view/30940
Acne vulgaris is a chronic skin disease with multifaceted cause. The exact etiology and pathogenesis of acne are yet to be established completely and various causative factors are considered as pathogenic mechanisms in the development of this disorder. We designed a study to determine the extent of serum trace elements, macrominerals and antioxidants in patients with acne, and thereby, to find the pathophysiological correlations, if any. Serum trace elements and macro-minerals were determined by flame atomic absorption spectroscopy. RP-HPLC was used to quantify antioxidants. Significantly (p<0.05) decreased level of zinc (1.90±0.06 vs. 2.17±0.09 mg/L), calcium (115.64±4.84 vs. 197.05±7.11 mg/L) and vitamin A (0.2±0.06 vs. 0.86±0.26 μmol/L) was found in patient when compared with the corresponding controls. This investigation suggests a commendable association between the pathogenesis of acne vulgaris with the reduced level of zinc, calcium and vitamin A which could well be used as a diagnostic tool for acne vulgaris.

Dhaka Univ. J. Pharm. Sci. 15(2): 215-220, 2016 (December)
 Salma Ahmed Rubaiya Ali Md Reazul Islam Md Anamul Hoque Abul Hasnat Zabun Nahar Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 215 220 10.3329/dujps.v15i2.30940 Bioactive Steroid and Triterpenoids from Bridelia stipularis (L) Blume http://banglajol.info/bd/index.php/JPharma/article/view/30941
Fractionation and purification of stem bark extract of Bridelia stipularis growing in Bangladesh afforded glut-5(6)-en-3-one (1), glut-5(6)-en-3α-ol (2), and (22E)-7-hydroxy-28-methylcholesta-4,22-dien-3-one (3). Compound 3 appears to be new, while compounds 1 and 2 have never been reported from this plant. The isolated compounds isolated exhibited cytotoxic activity against brine shrimp nauplii having significant LC50 and LC90 and moderate to strong antimicrobial activity against 13 Gram positive and Gram negative bacterial strains and 3 fungi. Here, compound 1 demonstrated highest inhibition of growth of microorganisms with zone of inhibition of 22.7 mm against Escherichia coli and compound 2 displayed zone of inhibition of 20.8 mm against Candida albicans. Compounds 1-2 also revealed moderate free radical scavenging activity in the DPPH method.

Dhaka Univ. J. Pharm. Sci. 15(2): 221-225, 2016 (December)
 Adeeba Anjum Md Zakir Sultan Md Al Amin Sikder Choudhury M Hasan Muhammad Abdullah Al Mansoor Mohammad A Rashid Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 221 225 10.3329/dujps.v15i2.30941 Design and Development of Bi-layered Sustained Release Azithromycin Tablets http://banglajol.info/bd/index.php/JPharma/article/view/30942
The objective of the current study was to develop a bilayer tablet of Azithromycin containing both immediate and sustained layer and evaluate the effect of formulation variables on drug release. Thirty different formulations (F-1 to F-30) were prepared by direct compression. When the fraction of polymer was increased from 5.55% to 10%, the rate of drug release was found to be slower. Maximum release of Azithromycin was from F-11 (within 8 hours), which contained 50 mg (5.55%) of HPMC 50 cps. Slowest release was observed from F-30 containing 90 mg (10%) of Carbopol 974 P. The IR spectral analysis revealed that all rate regarding agents and excipients used in this study are compatible with the active Azithromycin.

Dhaka Univ. J. Pharm. Sci. 15(2): 227-234, 2016 (December)
 Muhammad Rashedul Islam Md Mizanur Rahman Moghal FM Shah Noman Ul Bari Elias Al Mamun Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 227 234 10.3329/dujps.v15i2.30942 Preliminary In vitro Investigation of Antioxidant Potential of Ultra Short Acting Arylcarbamoyloxy-aminopropanols Containing N-Phenylpiperazine Moiety http://banglajol.info/bd/index.php/JPharma/article/view/30943
Abstract not available

Dhaka Univ. J. Pharm. Sci. 15(2): 235-239, 2016 (December)
 Lukas Stanzel Ivan Malik Petr Mokry Copyright (c) 2017 Dhaka University Journal of Pharmaceutical Sciences 2017-01-02 2017-01-02 15 2 235 239 10.3329/dujps.v15i2.30943


text:
Cheshire image bank
Search Cheshire Image Bank
About us/What's new
Searching the image bank
Popular collections
How to obtain prints
Donating Images
Contact us
Images of Cheshire's people, places & events
Picture of the month:
"Carriageway resurfacing in Frodsham Street, Chester, May 1925.
Latest news!
We are happy to announce that the photographic website of the Frodsham & District Historical Society has merged with Cheshire Image Bank. We can now offer an additional 4,500 images of Frodsham and area for you to enjoy.
The new images cover Frodsham, Helsby, Newton (Frodsham), Runcorn, Kingsley, Alvanley and Manley. Each entry includes a great description and additional information about the buildings, people and events taking place. Many images also show the area through modern colour photographs, too, so searching the pictures really shows how the area has changed over time.
Please let us know what you think of the new images via the "Can you help" link on each picture.
Text size
Terms & conditions
Site powered and designed by House of Images


text:
29th February 2012 - 0:46 | London UK, Putney | Age 65
Mature guy looking for younger guy for cock play. This works if you are into the older guy. Ideally want smooth type build with good size cock. No money arrangement but as i say if you're a youngish guy who enjoys the company of an older man then get in touch for some fun-details on receipt of your reply.
Ad No: 32952 | Views: 705 | Replies: 10 | Report Abuse


text:
From the Institute for Pathology (Drs Savic, Zlobec, and Bubendorf; Mr Grilli; and Mss de Vito Barascud and Herzog), University Hospital Basel, Basel, Switzerland; the Department of Pathology (Dr Bode), Institute for Surgical Pathology, University Hospital Zurich, Zurich, Switzerland; the Institute for Pathology (Dr Loosli), University Bern, Bern, Switzerland; the Institute for Pathology (Drs Spieler and Schönegg), Cantonal Hospital St. Gallen, St. Gallen, Switzerland; and the Division of Tumor Biology (Drs Franco and Herman), The Sidney Kimmel Comprehensive Cancer Center, and the Department of Pathology (Dr Clark), The Johns Hopkins Medical Institutions, Baltimore, MD.
Correspondence to: Spasenija Savic, MD, Institute for Pathology, University Hospital Basel, Schönbeinstrasse 40, 4031 Basel, Switzerland; e-mail: firstname.lastname@example.com
Funding/Support: This work was funded by a grant from the Krebsliga beider Basel [Grant 14-2008].
Reproduction of this article is prohibited without written permission from the American College of Chest Physicians (www.chestpubs.org/site/misc/reprints.xhtml).
© 2010 American College of Chest Physicians
Distinction of malignant mesothelioma (MM) from reactive mesothelial cells (RM) in effusions is notoriously difficult. The aim of our study was to test chromosomal aberrations detected by fluorescence in situ hybridization (FISH) in the diagnosis of MM in effusion cytology and to explore the potential role of p16, p14, and p15 gene methylation as an alternative mechanism of tumor suppressor gene inactivation.
Fifty-two effusions of biopsy-proven MM and 28 benign effusions were retrospectively analyzed by multitarget FISH assay for aberrations of chromosomes 3, 7, 17, and 9p21. In case of a negative result, the corresponding MM biopsy specimen was analyzed. Methylation-specific polymerase chain reaction (MSP) for p16, p14, and p15 was performed on FISH-negative MM biopsy specimens.
Seventy-nine percent of effusions with biopsy-proven MM had chromosomal aberrations, with loss of 9p21 as the most common finding. All benign effusions were FISH negative. Sensitivity, specificity, and positive and negative predictive values for detection of MM by FISH were 79%, 100%, 100%, and 72%, respectively. Six of nine FISH-negative effusions with biopsy-proven MM were also FISH negative in the MM biopsy specimens. Four of five FISH-negative biopsy specimens showed promoter methylation in p16 and p14 as compared with one of 12 benign controls.
FISH is a sensitive and highly specific method for the definitive diagnosis of MM in effusion cytology. In the subset of FISH-negative MM, tumor suppressor genes on the chromosomal region 9p21 are often inactivated by promoter methylation.
Become a CHEST member and receive a FREE subscription as a benefit of membership.
Individuals can purchase this article on ScienceDirect.
Individuals can purchase a subscription to the journal.
Individuals can purchase a subscription to the journal or buy individual articles.
Learn more about membership or Purchase a Full Subscription.
Institutional access is now available through ScienceDirect and can be purchased at myelsevier.com.
Some tools below are only available to our subscribers or users with an online account.
Download citation file:
Customize your page view by dragging & repositioning the boxes below.
Enter your username and email address. We'll send you a reminder to the email address on record.
Athens and Shibboleth are access management services that provide single sign-on to protected resources. They replace the multiple user names and passwords necessary to access subscription-based content with a single user name and password that can be entered once per session. It operates independently of a user's location or IP address. If your institution uses Athens or Shibboleth authentication, please contact your site administrator to receive your user name and password.


text:
The former top administrator of Beijing Capital International Airport (PEK) has been sentenced to 12 years in prison by Chinese authorities for taking bribes and kickbacks in return for providing favorable contracts and jobs to airport vendors and others.
Former Beijing Airport Chief took $750K in Bribes
Zhang Zhizhong's illegal activities reportedly took place between 1996 and 2009. China's state media says the man took in nearly $750,000 over the years.
Beijing: Soon to be 'World's Busiest Airport'
According to the Washington Post, Zhang's case was "one of a recent slew of dismissals and reports of graft investigations in China's aviation industry, which is rife with opportunities for bribery and influence peddling." Officials are also investigating other key state industries in an effort to root out corruption.
Harsher Sentence for Previous Airport Chief
Just two years ago, Chinese authorities carried out the harsher penalty given to Zhang's predecessor at the airport when he was convicted of embezzling more than $10 million in public funds: that ex-airport head received the death penalty.
Asia's Singapore Airlines Introduces New Low Cost Carrier
Beijing's airport is the main international gateway to the Chinese capital and is the busiest airport in Asia in terms of passenger traffic and total traffic movements.


text:
Waveform will be available soon!
All rights reserved. No usage without prior licensing. Please be fair. Thank you!
A huge and wide sound epos! Big percussions, a phat beat and contemporary orchestral elements! Go for it!
The phoenix rises from the ashes – heroic film music Hollywood style. A calm beginning evolves to a big movie score with full orchestra and big percussions.
A big percussion ensemble is creating a very positive African mood. Excellent for cutting.
A big percussion ensemble is creating a very positive African mood. Guitars and a solo flute are playing the main melody. Excellent for cutting.
Film scores: Amazement/Wonderment
Film scores: Victorious/Triumphant
Film scores: Dramatic Trailers


text:
It looks like you're new here. If you want to get involved, click one of these buttons!
I have 70 km per week. Is it enough for maraton?
depends how you're training... if you're running to fast or slow your wasting your time.
So usually i have a week like this: 35 km - pace 5 min/km, 18 km - min/km 10 km - 4 min/km 5 km - 3:15 min/km, 2 km - 3 min/km, 2 days for relax
ok but hard to help still - do you want to be faster im guessing so?
first you need to reflect on your health, are you healthy or is what you're doing now too much for you ie are you tired, get colds often, or injured often? if so you need to cut back the training and you will find you get better from doing that, simply because your body will be healthier.
I have usually got such plan of trainings:
Mo: rest
Tu: (4 km pace 4:50)+(5x800m pace 3:15, jogging between 2,5min)+(3 km pace 5:00) or (4 km pace 4:50)+(6km pace 3:35)+(3 km pace 5:00)
We: 10 km (pace 5:00)
Th: 15 km (pace 4:30)
Fr: rest
Sa: (4 km pace 4:50)+(8x200m pace 2:35, jogging between 250m)+(3 km pace 5:00) or (4 km pace 4:50)+(10x100m for 15 sec every 100, jogging while pulse


text:
Two Dark-haired Dudes Are Sucking Each Other's Dicks Video offered by e-HDPorn.Net
Related Videos
- 14:28Two Attractive Hotties Fuck Before He Blows Spunk89% Like2 years ago
- 25:45Gay Guy And His Fuck-buddy Are Blowing And Having Anal Sex89% Like12 months ago
- 14:35Brunette And His Freind Are Blowing And Fucking88% Like12 months ago
- 21:02Homosexual College Students Are Kissing And Fucking89% Like2 months ago
- 11:34Gay Military Men Slurping Down Dickhead85% Like2 years ago
- 16:56Hot Brazillian Bros Have Some Rectal Sex88% Like2 years ago
- 20:01Pornstars With Big Cocks Blow Each Other's Stiff Dicks94% Like7 months ago
- 21:33Two Hot Studs Reunite To Suck & Fuck92% Like2 years ago
- 13:35A Handsome Exotic Guy And His Fuck-friend Are Sucking And Having Anal Sex85% Like2 years ago
- 16:18Tight Ass Latinos Fucking Hard95% Like6 months ago
- 16:25Couple Of Dudes Enjoy Some Ass Licking On The Couch84% Like2 years ago
- 33:41A Couple Of Gay Dudes Fuck Each Other's Asses In The Living Room95% Like3 months ago
Enjoy Two Dark-haired Dudes Are Sucking Each Other's Dicks video offered by e-HDPorn Net . Also you can add this free Sex video to your favorites or Add Two Dark-haired Dudes Are Sucking Each Other's Dicks to your site, to your blog using the embed codes of the Porn Video, pin it or share it to social networks (facebook, twitter , tumblr, google + ,delicious, digg , rebbit etc) or post it to adult forums. Be An Active Member of e-HDPorn.Net tube and connect with other community members


text:
Couldn't find any photos there Jim.
----- Original Message -----
From: "jim singer" <email@example.com>
To: <email@example.com>
Sent: Thursday, December 19, 2002 2:37 PM
Subject: [CHAT] desert wildflowers
> it was a slow day at the lugwart factory, so i borrowed a page from
> theresa's book and put up a yahoo briefcase of photos of desert
> wildflowers. i took these about 30 years ago in the spring in death valley
> [i used to camp there three or four time a year--whenever i want to get
> away from my wife for awhile]. i have no idea what most of them are; maybe
> someone who still lives out that way does. the only one i know for sure is
> the desert verbena.
> address is http://briefcase.yahoo.com/islandjim2003.
> oh yeah, there's also a picture of a barrel cactus that's to die for and a
> picture of a female coyote, who became almost friendly at one of my
> campsites. [the male was far more skittish.]
> email@example.com
> ---------------------------------------------------------------------
> To sign-off this list, send email to firstname.lastname@example.com with the
> message text UNSUBSCRIBE GARDENCHAT
To sign-off this list, send email to firstname.lastname@example.com with the
message text UNSUBSCRIBE GARDENCHAT


text:
Vw jetta 1984 for sale on US's largest classifieds sites (6 results)
1984 Volkswagen VW Jetta Coupe 8v Gas 5 speed
NO TRADES.$3500 - FIRM1984 VW Volkswagen Jetta Coupe - Mk11984 VW Jetta157,0005 speed manual transmission.Update: September 7th, 2016Updated front suspension: Spindles replaced with new wheel bearings and hubs, lower control arms replaced with new bushings , new bal
Year: 1984, Make: Volkswagen, Model: Jetta
1984 vw jetta rare turbo diesel
Finally time to let this gem go. I recently acquired a 1984 Volkswagen Jetta turbo diesel. It is a factory 1.6 liter made in Germany. An old woman owned it since 1984 up until 2010. She lef a pocket pal with everything done to the car since 1984. This car is like taking a trip back to 1984. Never been...
Year: 1984
1984 VW Jetta GLI
Daily driver Very cheap on gas and runs great and is pretty fast for an 84 and great manual trans but does need a shifter eventually I did replace all the bushings. has new water pump, master cylinder, brakes and fog lights. Has sunroof had ac but the belt broke but does work. What it needs: AC belt, ...
155,598 Miles
Year: 1984
1984 VW Jetta MK1 Turbo Diesel
: Super clean, low mileage rare Turbo Diesel Jetta 4 door 5speed. Peppy great MPG (48) Large trunk. Tires like new needs nothing. Clean title no damage, new sheepskin seatcovers. Will consider reasonable offers Call or text 213 587-1800
135,000 Miles
Year: 1984, Make: Volkswagen, Model: Jetta gl
1984 VW Volkswagen Jetta Diesel Car
THREE OWNER! 1984 Turbo Diesel VW Mk1 Jetta GL 5spd - 38-56MPG!
: Hello. Up for grabs is my beloved Jetta. It is a low mileage, Mk1 turbo diesel four door that runs and drives great. It has factory air (more on that) and CRUISE CONTROL! I have about $6k tied up in it and I will NOT take low ball offers. I do not really want to sell it, but it is the mo...
151,600 Miles
Year: 1984, Make: Volkswagen, Model: Jetta gl