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Several biopharma companies are working on therapeutic agents for AML that target CD33, including Amgen, Bayer, Boehringer Ingelheim, and J&J. However, only Actinium and Seattle Genetics (SGEN) have progressed beyond Phase 1 studies. For the purpose of my article today, I will look at Actimab-A compared to SGEN's SGN-CD33A.
CD33 is a transmembrane receptor leukocyte antigen primarily expressed on cancer cells of myeloid lineage, although it can also be found on some lymphoid cells. Regardless of age, risk factors, or underlying mutational heterogeneity, CD33 is consistently expressed in nearly 90% of patients with AML (1). It is a clinically and commercially validated target for monoclonal antibody therapeutics. As noted above, several biopharma companies are targeting CD33 for the treatment of AML.
SGN-CD33A - SGEN's CD33 2.0 Strategy
SGN-CD33A is an engineered antibody-drug conjugate (ADC) designed to deliver the cytotoxic agent pyrrolobenzodiazepine (PBD) dimer to myeloid leukemic cells. The antibody portion, vadastuximab, has engineered cysteines (EC-mAb) that link to the PBD dimer. Just like lintuzumab, vadastuximab binds to the CD33 protein on the myeloid leukemia cell, causing the complex to be internalized and trafficked to the lysosome. Once inside the cancer cell, PBD is released and binds to specific sites on the cellular DNA. This cross-linking blocks the cancer cells division without distorting its DNA helix, thus potentially avoiding the common phenomenon of emergent drug resistance.
- Some Areas Of Concern
I see some potential areas of concern around SGN-CD33A. The first is the potential safety of the drug. The company's Phase 1b dose-escalation program initiated in late 2014 tested 5 mcg/kg to 60 mcg/kg of SGN-CD33A. Results with the 40 mcg/kg cohort showed encouraging antitumor activity, with an impressive 77% demonstrating a 50% or more reduction in bone marrow blasts (5). However, treatment-related adverse events were common and included fatigue (57%), thrombocytopenia (53%), nausea (49%), febrile neutropenia (45%), and anemia (42%). The most common Grade 3 or 4 treatment-emergent adverse events occurring in 20% or more of patients were febrile neutropenia, thrombocytopenia, neutropenia, anemia, and fatigue.
Actimab-A - Targeting CD33 With a Radioactive Kick
This Phase 2 clinical trial is a multicenter, open-label study that will enroll 53 patients. Patients will receive 2.0 µCi/kg/fractionated dose of Actimab-A via two injections given at day 1 and day 7. The Phase 2 trial is designed to evaluate complete response rates at up to day 42 after Actimab-A administration, where a complete response is defined as complete remission (CR) or a complete remission with incomplete platelet recovery (CRp). A formal interim analysis is expected to occur in mid-2017 with topline results expected in the second half of 2017. An update on enrollment and an interim look at the first few patients is expected at the ASH conference in early December 2016.
- During analysis of the Phase 1 and previous studies stemming from the HuM195 conjugated alpha particles program, an interesting trend emerged where patients with low peripheral blast burden experienced the best clinical response.
- The protocol for the Phase 2 trial includes pretreating patients with hydroxyurea to reduce peripheral blast count. This should increase the response rate for all patients treated with Actimab-A. Additionally, the required use of low-dose cytarabine has been removed by the FDA for the Phase 2 portion, which should greatly improve enrollment rates and interest among investigators.
- CR/CRi/CRp for the dose Actinium plans to move forward with into Phase 2 (2 x 2 μCi/kg) in patients with low peripheral blast burden was 50%, matching the impressive data from Celator's VYXEOS™ at 48% reported in March 2016. As a reminder, Jazz acquired Celator for $1.5 billion in June 2016.
- Initial data expected at ASH in December 2016, which is less than two months away.
BioNap is long shares of ATNM.


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Tips To Take To The Beauty Salon For Wedding Day Make-Up That Is Perfect
... of age and hold a high school diploma or GED.
Another benefit of Utah Beauty Schools is that you'll be able to work in an atmosphere that doesn't have the restrictions of an office. Some people aren't cut out to work in the corporate world. They enjoy having a little more freedom and fun and can progress through a career that will match their personality.
32. Prior to going shopping, make a list of only those items you need and only purchase those. ...
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If you or someone you know does calligraphy, you can give your documents a more elaborate touch. Calligraphy printed on parchment paper and beautifully framed is the perfect I love you gift.
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... br>
Most of the packs come with nail size templates so you can judge which size is right for each finger although some may need a trim. This is easily done with small scissors.
Gather as much information as you can about all the Utah Beauty Schools in your area. Get to know about the courses they offer, the training methods, and if possible, visit the campus.
Take in TV Shows on Fashion. The Clothes Show on ...
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... work, volunteer to do any at-home work for her (shopping, errands, cleaning, caring for children). Ask her to make a list of what needs doing. Send her to the library, coffee shop, gym, out to lunch with dad or some of her friends or any other place she would enjoy.
Jenelle and Kieffer hopped in the car and headed off to the magistrate to file charges against Barbara and Mike. Jenelle waited in the car while Kieffer went inside. They each ...
What Exactly Is Beauty School?
... skills and talents.
Time-expect any service done at a beauty school to take a little longer. Average time for a haircut is 1 hour. Average time for color (depending on length etc) is about 2 hours. Keep in mind the student is learning. I have found this time factor was a positive thing for me - I get what i want. The previous stylist who did my hair would have me in and out (styled and washed) in 30 minutes. Towards the end she didn't even listen to what I wanted. ...

subset: commoncrawl


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The landlord does not accept the following in this place:
Are you moving to Rome to discover this lovely city while studying there and you need to find a quiet place to live? Check out this nice apartment in the Quartiere XXXII Europa, it might be exactly what you're looking for. You'll have some coffee shops, restaurants and stores around as well as transport links such as the Magliana train station, that can take you to the city centre in a minute.
The property has a total of six bedrooms, two common bathrooms, a kitchen and a living room. The available bedrooms are quite charming and comfortable - ideal for any student. The kitchen has all the necessary appliances for your cooking adventures and the living room is simple but it does offer the comforts of home.
Another thing you should know is that outside, there's a nice yard at the back.
Find out more about this property's common areas in our photo gallery.
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Getting Around
Path to university
At Uniplaces we make the process of booking an apartment as easy as possible for both tenant and landlord.
That's why we have our own team of professional photographers that verify our properties and pick our landlords carefully in order to save time on viewings: we think it's old-fashioned and time-consuming.
You can look at forty different apartments on our platform in the same amount of time that it takes to see a room.
The pictures you see here haven't been photoshopped, so they'll be really accurate.
If you've still got any doubts, we'll keep the money that you transfer us until 24h after your move-in date.
If something's not exactly what you saw online, we'll help you move somewhere else and return your money.
We can only give you the contact details of your landlord after your booking is accepted. But we can guarantee that Uniplaces chooses the landlords it works with very carefully.
Besides, we've had students whose favourite part was living with a local!
Landlords and host families can be great city guides, help you out with translations and even become your friends.
As soon as your booking is accepted, you're given the landlord's contact details. Then, you can discuss all details directly with them, such as when you'll be moving-in.
Students move in and out at different times, so your flatmates might change during your stay.
It's a great opportunity to make new friends!
We personally speak to students who we place in Uniplaces apartments and are sure we will find the right place for you as well!
At the bottom of the property page, you have a calendar where you can see the availability of that room/apartment, according to the landlord.
But if you're still unsure about that we're happy to help.
Tell us your move-in and move-out dates and we will double-check if the place is available for you!
There are two different types of deposits: the Holding and Security deposits.
By clicking on "Deposit" at the bottom of the offer page you will get more information about each type of deposit.
In general, the deposit is paid to cover for any potential damages that may occur during your period of stay or will be used as rent compensation in case you leave earlier than originally planned.
If no damages occur and you leave on the agreed move-out date, your deposit should be refunded by the landlord in a way you both agree on.


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Why is Britain still a permanent member of the United Nations security council? This will be the question on the lips of every ambassador around the world as they see our global role shrink before their eyes.
Yesterday, the French started supporting the Kurds with military hardware to help protect themselves from the blood thirsty militants of ISIS . Meanwhile, David Cameron was still unpacking his swimming trunks.
As a country, we are paralysed with indecision, indifference and lack of will on the international stage. It's embarrassing.
And worse still - whilst our strategic interests in the Middle East are unraveling, our position in Europe diminishing and our Atlantic influence withering, David Cameron has allowed a referendum on the integrity of the United Kingdon itself.
He is grave danger of being the Prime Minister that takes the UK to the international equivalent of Lichtenstein - a country stuffed full of bankers but with no useful role in the world.
Even if the PM knew what to do in Iraq, he would find it hard to act.
The decision taken by this government to accept a gap between scrapping our carrier strike capability and constructing a new one has left us without the capacity to project force effectively in a key region of the world.
It gets even worse - he's slashed the army, creating an over-reliance on reserve forces.
The full impotency of our military options in Iraq will haunt the Prime Minister for the rest of his premiership.
It was a grave strategic mistake to scrap the Harrier jets. He knows it, our military knows it and our enemies know it.
It's hard make these points in the current febrile debate about austerity Britain, but whoever wins the next election is going to have to build more ships for the Royal Navy and take the defence of our country seriously once again.
Britain has a foreign policy vacuum of which our ill thought out defence capability is a symptom. In 2014, as we look back on a hundred years since the start of the first world war, the one front that is stable, and not militarily active is the western front. God bless the EU for keeping us at peace.
Cameron, further weakened before an election, has been completely distracted by anti-european forces on the right that make it harder for him to take a big global view.
The little Englanders and the little Scotlanders that seek to divide the UK within itself and from Europe are a menace that needs to be defeated.
A future Labour government should call them out for what they are - blinkered fools lacking imagination.


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The energy investment unit of General Electric (GE) joined an international consortium to buy 32 wind farms in France for about $461.8 million.
GE Energy Financial Services will own 40% of the portfolio, which have a combined capacity of about 321.4 megawatts. MEAG, the asset management arm of German reinsurance firm Munich Re, will also take 40%. Energies Nouvelles, a subsidiary of the French utility EDF Group, will own 20%.
The seller, Spanish utility Iberdrola, said the deal helps it strengthen its balance sheet.
Energies Nouvelles will maintain and operate the wind farms. And the group plans to upgrade some of the equipment with GE technology.
In a statement, Andrew Marsden, a managing director of the GE unit, said his company plans "to seek additional opportunities to expand our renewable energy assets in Europe."
GE shares rose 1.6% to 21.32 Wednesday.
In November, GE announced it had deployed its 20,000th wind turbine.
Two weeks ago GE announced an $11.4 million contract to provide spare parts, maintenance and repairs on 26 wind turbines in Taiwan over the next five year.


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Crossing the Finish Line
On September 12, 2007 by Donncha With 1 Comments - Blarney, Candid, Canon 20D, Cork, Ireland, People, Photos, Sigma 10-20, Sky, Urban
Three girls run past the "Finish" line after the Blarney half marathon on Sunday.
It was a funny place to put that sign as it was well behind the actual finish line. Guess they didn't have any poles to stick it up on ..
One Comment
September 14, 2007
we really miss you a lot
Jesse, Carlos, Leslie, Janna, Emily , and Nick


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Stanford Business Magazine showcases ideas and activities of the alumni, faculty, and students of the Stanford Graduate School of Business. This app includes issues dating from Autumn 2010. New issues will be available for download three times a year in a format similar to the print magazine, but excluding the class notes which are available online to alumni only.
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text: Coonskin bridge funding complete By Rusty Marks August 27, 2013 Story Share CHARLESTON, W.Va. -- Members of the Kanawha County Commission voted to spend $1.5 million Tuesday night, which is the final piece of the funding puzzle needed to build a new bridge to Coonskin Park and better secure the National Guard's 130th Airlift Wing.State and local officials say the new bridge is mandatory to close off Coonskin Drive to the public and keep the federal government from closing the 130th Airlift Wing.When the federal Base Realignment and Closure Commission tried to shut down the 130th in 2005, base security was one of the arguments it used. Coonskin Drive, which runs from Greenbrier Street to Coonskin Park, also runs right past the 130th Airlift Wing headquarters and a National Guard armory.State and local officials want to close off Coonskin Drive to the public and build a new entrance to Coonskin Park across the Elk River in the Mink Shoals area. Gov. Earl Ray Tomblin, state Adj. Gen. James Hoyer, officials for Yeager Airport and members of the Kanawha County Commission all agree Coonskin Drive must be closed to survive another round of federal base closures. Hoyer said the 130th and armory create about 1,100 part-time and 350 full-time jobs, and contribute about $89 million to the local economy.The 130th, which shares a mountaintop with Yeager Airport, also provides security and fire protection for the airport. Airport Director Rick Atkinson has said the airport might be forced to shut down if it loses the 130th and has to build a new fire station and pay for emergency and fire service.Hoyer said the bridge is expected to cost between $9 million and $11 million. The late Sen. Robert C. Byrd, D-W.Va., tried to get money for the new span included in the federal budget, but died before the money could be secured.State and local officials have agreed to pick up the tab. County commissioners Kent Carper, Dave Hardy and Hoppy Shores voted unanimously to put $1.5 million in county money toward the project. Carper said the Yeager Airport board has also agreed to $1.5 million in funding.Hoyer said the rest of the money for the bridge will come from the state and the National Guard. He said the project will be bid out in September, and could be completed within two years.As thanks for their support for the National Guard, Hoyer presented county commissioners with a framed commissioned painting that represents the long history of the West Virginia National Guard's contributions to national defense."We have been a part of the national defense since before we were even a state," Hoyer said. Called "The Beeline March," the painting portrays militiamen from Shepherdstown who, in 1775, marched 600 miles in 25 days to Cambridge, Mass., to answer a call from George Washington, helping to form the fledgling Continental Army.Hardy said voting for the bridge was the easiest decision he's made in 12 years on the County Commission.Carper called the decision a "no brainer." "We did this because we know it's the right thing to do," he said.County officials aren't yet sure how they'll pay for the contribution, but at least some of the funding will come from coal severance taxes.Also Tuesday, Carper asked county tax officials to come up with a plan to collect $12 million in past due property taxes. Chief Tax Deputy Allen Bleigh said thousands of county residents and businesses haven't paid their taxes, some for years. Bleigh said the worst offender is Martin Twist Energy, a Kentucky-based oil and gas company that owes about $3 million in back taxes. He said tax officials are in the process of suing the company to get the money.County officials said they have tried everything from hiring collection agencies to full-blown threats to get delinquent taxpayers to pay up, with varying degrees of success. Carper gave Bleigh 30 days to come up with a plan to recover what he could of the $12 million in unpaid taxes.Reach Rusty Marks at firstname.lastname@example.com or 304-348-1215. Story Share Story Share Trending Now 1 Free mobile dental clinic to visit 6 WV counties 2 Charleston population continues slow bleed, 2016 Census shows 3 Justice revives bill shifting tax burden for education 4 WV groups hope study leads to end of mountaintop removal mining 5 Trump dumps 'clean coal' research he praised in campaign Quarrier Diner to reopen in September Previous Story Appalachian Power rates could go down next week Next Story


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Sharing the Orton-Gillingham Approach
Led by seasoned Orton-Gillingham Fellow Janet Jones, Trident Academy held its annual Orton-Gillingham Associate Level Summer Institute for Educators on July 14 – 24. This 10-day, 60-hour course, which qualifies attendees for Associate Level certification with the Academy of Orton-Gillingham Professionals and Educators (AOGPE), provides the opportunity for participants to learn an effective approach for teaching children with language-based learning differences. The participants are taught how to instruct students diagnostically and prescriptively in both a classroom and in one-on-one instruction. In addition to their coursework during the day, participants have homework each evening as well as a reading list.
Among the 13 attendees for this summer's training were a mix of public and private school teachers as well as a few parents. Two faculty members from the Dorchester County School District, along with a public school teacher from Indiana, three parents, a psychologist, faculty members from Trident Academy, as well as other area private schools gathered on the school's campus for the course. Attendees learned about things such as:
- The characteristics of the dyslexic learner
- The Orton-Gillingham approach
- Informal Assessment, the student profile
- Structure of the English Language; Phonology
- Multi-sensory teaching
- Diagnostic and prescriptive teaching, developing an individualized lesson plan
Janet Jones is a longtime Orton-Gillingham practitioner, having first become involved with the approach in the 1970's. As Janet remembers it, "I started an internship in the Orton-Gillingham approach after my freshman year of college when I went back to my parent's home in Puerto Rico. That was in 1973!" Janet returns to Trident Academy after a five-year absence, having served as a faculty member from 2005-2009. She now serves as the Director of Orton-Gillingham. Janet's undergraduate degree is in Speech and Language Pathology from Northwestern University and her graduate degree is in Learning Disabilities from the University of Wisconsin. With Janet's 40 years experience in Orton-Gillingham and her expertise with learning disabilities, Trident Academy's Orton-Gillingham program is in excellent hands.
According to Nicole McLain, our Program Director who took Janet's Orton-Gillingham training course, "This program is the foundation of our school. We teach children in a diagnostic and prescriptive manner that is tailored to each child individually. To do this in a systematic and sequential approach takes skill, knowledge and extensive training. This Orton-Gillingham course is magnificent in helping anyone – a parent, teacher, specialist or professional – about the necessity of individualization and scope and sequence that comes along with the Orton Gillingham approach."
To learn more about the Orton-Gillingham approach or upcoming training opportunities, contact Janet Jones.


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Environment issues
Advice on environmental health, pest control, pollution and animal welfare.
Pest control We provide a comprehensive pest control service in Bexhill, Battle, Rye, the district of Rother and surrounding areas. Find out more about Pest control
Food hygiene The Food Hygiene service exists to ensure that food is safe to eat for the residents and visitors of Rother. Find out more about Food hygiene
Dog control Finding the owners of lost dogs, investigating allegations about aggressive dogs and dog fouling are all part of our work. Find out more about Dog control
Noise Information about how we deal with noisy neighbours, noise from commercial premises and transportation noise. Find out more about Noise
Contaminated land Find out what The Council's objectives are with respect to contaminated land and view the contaminated land strategy. Find out more about Contaminated land
Leaflets Environmental Health General Leaflets Find out more about Leaflets
Drainage and sewage Rother District Council dealt with over 200 calls last year to do with drainage problems. Find out more about Drainage and sewage
Caravan sites There are currently just over 100 caravan sites in Rother. These are made up of holiday sites, permanent residential sites and touring sites. Find out more about Caravan sites
Contact Environmental Health Environmental Health is run as a shared service between Rother and Wealden District Councils. Find out more about Contact Environmental Health
- ■ Fly-tipping
- ■ | Air quality
- ■ | Rubbish
- ■ | Environment policy
- ■ | Public registers
- ■ | Public health archive
- ■ | Environmental Health Performance


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Jovita: It has been diagnosed, I have Stampede Lag. It is like jet lag, only from not sleeping at the Stampede and then being thrown back into the real world Monday morning. But would I trade one minute of the Stampede I experienced for sleep? Never. The ten days of early mornings, late nights, and hot afternoons Arielle and I got to participate in can never be replaced. It was a once-in-a-lifetime chance to experience the 100 year anniversary of the Stampede, let alone as an Ultimate Intern!
I could gush all day about all the events we got to go to, but you have already read those blog posts. Instead I will express my immense gratitude at being able to work with the Stampede and meet the staff and volunteers. Incredible patrons aside, the Stampede staff and volunteers put on the Greatest Outdoor Show on Earth with hard work, pride, and hospitality and have blown everyone away with the centennial celebration. Happy Birthday Calgary Stampede, and thanks for the memories.
Arielle: I'm craving mini donuts, crazy rides, spectacular shows and two-stepping. But most of all I'm craving the people. Now that I am back to the real world, I have been asked many times what my favorite was at the Stampede. Easy – the people I've met.
I have fallen in love with Calgary and the Calgary Stampede all over again because of the dedication, energy and graciousness I have witnessed from volunteers, employees, and fellow Stampeders. Being present during all 10 days of the Calgary Stampede, let alone being backstage or front of the line for most of it, has been one of the most amazing things anyone can experience. I feel (oh so ridiculously) blessed to have been a part of this and am grateful to those who joined me in my adventures online. I hope you had a blast. Until next year. Xo.
Read our adventures here!


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Frozen fans can add some cool to their outfit with this bucket hat. Soft poplin construction, Olaf in the pool print, "Chillin'" embroidery.
Customer with a shipping address in eligible NY Metro areascan choose
at checkout, to get their order delivered on the same business day.
Just place your order by 9AM and choose "Same-Day Delivery".Orders placed after 9AM or on a weekend/holiday will be delivered the next business day.


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Posted by Fatemeh Khatibloo on the Customer Insights Professionals Blog on October 7, 2015
Yesterday morning, many of us in the United States awoke to some troubling news: the European Court of Justice (ECJ) had ruled that the Safe Harbor agreement is no longer valid. Security & risk (S&R) and data management folks kicked into high gear. Customer insights and digital marketing teams...? Well, the news slipped past mostly unnoticed. That's a mistake.
Let's start with a primer on Safe Harbor. If you're a multinational company doing business in Europe, Safe Harbor is the agreement under which you've been allowed to bring European customers' data back into your servers in the US for purposes of targeting, analytics, campaign management, etc. If you work with a US-based database MSP, digital or CRM agency to manage customer data, they've likely been relying on the same agreement. It's a nearly 20-year old agreement that was put in place to bridge the gap between Europe's strict data protection laws and America's relative dearth of them.
Now, that agreement has been deemed invalid, which means that every company serving European customers needs to reexamine its data practices. Of course, this is primarily the purview of our technology management peers. But customer insights professionals need to partner closely with them on two fronts:
Posted by Heidi Shey on the Security & Risk Professionals Blog on May 1, 2015
A guest post from researcher Enza Iannopollo.
Upcoming changes to privacy regulation in the EU as well as rising business awareness that effective data privacy means competitive differentiation in the market makes privacy a business priority today. And this is not only relevant for tech giants: protecting both customer and employee privacy is a business priority for companies of all sizes and across industries.
But where do you start? Many companies start by hiring a chief privacy officer. Some have built brand-new privacy teams that manage privacy for the whole firm, while others prefer a decentralized model where responsibilities are shared across teams. What are the pros and cons of each approach? Which organizational structure would better meet the needs of your firm?
And when your privacy organization is in place, how do you establish smooth collaboration with other teams like marketing and digital, for example? Too often we hear that privacy teams do not have the visibility that they need into the data-driven initiatives happening within the company. When this happens, privacy organizations are less effective and the business risks failing its customers, undermining their expectation for privacy.
Posted by Fatemeh Khatibloo on the Customer Insights Professionals Blog on March 26, 2015
Earlier this year, I had the pleasure of moderating a panel of leading privacy professionals for the Churchill Club.
During the session, we recapped the highlights—and lowlights—of privacy in 2014, discussed some of the major trends and issues in the space, and made some predictions for 2015 and beyond.
What stood out for me, as a customer insights (CI) professional, is how critical our teams are to the work of privacy and how much we must guide the process of contextual privacy. There is a lot of work to be done to build stronger organization-wide consensus around better privacy. Like they were the nexus point between business technology and marketing teams, CI pros are now the nexus between security, legal, and marketing teams.
I've linked the full session below. Please enjoy, and please consider getting involved in Data Privacy Day 2016 - the effort could use more marketers and business leaders.
Posted by Martha Bennett on the CIOs Blog on June 10, 2013
Notes from the TechAmerica Europe seminar in Brussels, March 27, 2013
This may not be the most timely event write-up ever produced, but in light of all the discussions I've had on the same themes during the past few weeks, I thought I'd share my notes anyway.
The purpose of the event was to peel away some of the hype layers around the "big data" discussion, and — from a European perspective — take a look at the opportunities as well as challenges brought by the increasing amounts of data that is available, and the technologies that enable its exploitation. As was to be expected, an ever-present subtext was the potential of having laws and regulations put in place which — while well-intentioned — can ultimately stifle innovation and even act against consumer interests. And speaking of innovation: Another theme running through several of the discussions was the seeming lack of technology-driven innovation in Europe, in particular when considered in the context of an economic environment in dire need of every stimulus it can get.
The scene was set by John Boswell, senior VP, chief legal officer, and corporate secretary at SAS, who provided a neat summary of the technology developments (cheap storage, unprecedented access to compute power, pervasive connectivity) giving rise to countless opportunities related to the availability, sharing and exploitation of ever-increasing amounts of data. He also outlined the threats posed to companies, governments, and individuals by those who with more sinister intent when it comes to data exploitation, be it for ideological, financial, or political reasons. Clearly, those threats require mitigation, but John also made the point that "regulatory overlays" can also hinder progress, through limiting or even preventing altogether the free flow of data.
Posted by Dan Bieler on the CIOs Blog on July 4, 2012
Google Enterprise as a division has been around for some time, but it is only fairly recently that Google started to push the enterprise solutions more actively into the market through marketing initiatives. The cloud-delivery model clearly plays a central role for Google's enterprise pitch (my colleague Stefan Ried also held a presentation on the potential of cloud computing at the event).
Still, the event itself was a touch light on details and remained pretty high level throughout. Whilst nobody expects Google to communicate a detailed five-year plan, it would have been useful to get more insights into Google's vision for the enterprise and how it intends to cater to these needs. Thankfully, prior to the official event, Google shared some valuable details of this vision with us. The four main themes that stuck out for us are:


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International music star Mika sets sights on U.S.
By Richard Smirke
LONDON (Billboard) - At first impression, the man no one knows as Michael Penniman seems uncharacteristically quiet. As he takes a well-earned break from rehearsing for a tour to promote one of the year's most eagerly anticipated music releases, he seems tired and anxious, a far cry from his usual ebullience.
He knows it, and he apologizes politely for his demeanor before taking a drawn-out pause to refocus and return as the witty, charming, unashamedly upbeat force of nature the world knows and (mostly) loves as Mika.
"It's always a big stress figuring out how to do things live," he says, becoming more animated with every word. "It's really kind of terrifying. I wish I could just mime. I'd be so much happier."
"I'm joking, of course."
"Witty," "charming" and "unashamedly upbeat" are also words that could be used to describe Mika's music -- a winning mix of radio-friendly piano ballads, sexual ambiguity and melodic pop. His debut album, "Life in Cartoon Motion" (Island/Universal), sold 5.5 million copies worldwide, according to his handlers at London-based Machine Management.
His U.K. base -- Mika was born in Lebanon but has a dual U.S. and British citizenship -- contributed 1.6 million of those copies, and Mika regularly leaves his London apartment to find gifts from fans or even fans themselves, camping overnight outside his door. Continued...


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|Powerade gives Celtics fans figurative middle finger
|07.13.12 at 1:04 pm ET
Only a few miles north of Boston, Powerade unveiled an electronic I-93 South billboard that reads, "Congrats, LeBron. Championship has a nice ring to it," as reported by the Boston Metro.
Just weeks after the Heat's LeBron James averaged 33.6 points, 11.0 rebounds and 3.9 assists per game to defeat the Celtics in a seven-game Eastern Conference finals, what better time for the sports drink company to remind Boston basketball fans of their most recent heartbreak? At least Butterfinger wasn't behind dropping 900 pounds of the candy bars on Copley Square in thanks to Wes Welker for his drop in Super Bowl XLVI.
I'm guessing Gatorade sales just soared in New England. No word on James' awareness of the Boston campaign. Maybe Zico should unveil a Kevin Garnett ad in Miami reading, "Congrats, LeBron. Suck on my coconut water."
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text:
This is a simple virus which is more or less extinct today.
Automatic action
Depending on the settings of your F-Secure security product, it will either automatically delete, quarantine or rename the suspect file, or ask you for a desired action.
More scanning & removal options
More information on the scanning and removal options available in your F-Secure product can be found in the Help Center.
You may also refer to the Knowledge Base on the F-Secure Community site for more information.
Contact Support
F-Secure customers can request support online via the Request support or the Chat forms on our Home - Global site.


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Home › Forums › Off Piste › Mountaineering & Alpinism › mad rock boots?
@pyeyoLocale: pacific northwest
Does anyone have any experience with the MadRock Alpinist boot? It is being touted as an alternative to the plastic fantastics.
I just got a pair of two days ago. I think they are great! I have only had the chance to climb with them indoors on an artificial ice wall with step-in crampons.
-Everyone I know that owns the boot finds it hard to slide their foot into the boot, but once your foot is in the boot they are comfortable.
-They are very rigid.
-I normally wear a 10 – 10.5 sized boot, but I purchased an 11 so that I can wear extra thick socks and still have some dead air space.
@sharaldsLocale: Gallatin Range
We sell these at the gear shop I work for part time. Earlier this season Mad Rock sent us a whole box of them for us to demo out at the Sandstone Ice Fest. I worked the demo tent so I got to hear lots of feeback on a whole slew of gear that was available for demo that day. Amongst these was obviously the Mad Rocks.
People did in fact find them hard to put on as they are a very stiff boot. Some concern was mentioned by one individual that they were not the most comfortable boot for walking in but that the climbing was superb (consequently this individual just purchased a pair of these boots this week).
Overall I heard good things about their ability to accept the crampon, their feel on the ice and their fit. So take into consideration the possibility of an uncomfortable approach but a comfortable and stable climb.
@pyeyoLocale: pacific northwest
In the past I've really struggled to get my feet into anything with a neoprene collar or tight upper so I do appreciate the input, I'm going to wait to try some on somewhere… mad rock products seem scarce in the northwest.
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TED Talks audio
Listen to TED Talks on your favorite audio or streaming device. Whether you're a Google Home or Amazon Alexa user, you can now play the latest TED Talk.
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text: Haze: Privacy-Preserving Real-Time Traffic StatisticsJoshua W. S. Brown, Olga Ohrimenko, Roberto TamassiaSIGSPATIAL/GIS2013We consider mobile applications that let users learn traffic conditions based on reports from other users. However, the providers of these mobile services have access to such sensitive information as timestamped locations and movements of its users. In this paper, we introduce the model and general approach of <i>Haze</i>, a system for traffic-update… (More)


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I need to export to a file all the softwae installed per PC not as a whole.
1 Reply
· · ·
Dec 7, 2007 at 2:04 UTC
Sam IT is an IT service provider.
May not be exactly as you would like to see it, however if you add "Installed Applications" to some computer report then you will get the installed applications per computer.


text:
|Message view
|« Date » · « Thread »
|« Date » · « Thread »
|Karl <k...@webmedia.co.nz>
|RE: Unusual problems with POST method
|Thu, 17 Feb 2000 19:44:48 GMT
Hi, Perhaps it is the .htm suffix of your URL - is that a typo? It maybe that the server is disallowing posts to what it believes are HTML files? k@rl ---- Last minute heroics seldom run to schedule. -----Original Message----- From: root [mailto:email@example.com] Sent: Friday, February 18, 2000 4:06 AM To: firstname.lastname@example.com Subject: Unusual problems with POST method Hi everybody, I installed the tomcat in my Red Hat and all the examples are working fine, including the RequestParam example (which uses doPost method to get the parameters values from console). I wrote a simple servlet (named SimpleServlet.java) that uses the doPost method too, and it's based on RequestParam servlet, but when i tried to make it work (using my correct server adress: http://localhost:8080/SimpleServlet.htm) , and i got a message: "Error 400 - Method POST is not supported by this server." I tried different locations for classes, including the /examples/WEB-INF/classes/, and the message was the same ever. I also tried to copy the RequesParam.* to another directory ($tomcat_home/webpages/WEB-INF/*) and the RequestParam.html too, but still doesn't work (same error). I noticed that the error wasn't a code-error fault, but maybe something in my jakarta server config. Can anyone help me? Thanks, Daniel L. de Arola --------------------------------------------------------------------- To unsubscribe, e-mail: email@example.com For additional commands, e-mail: email@example.com
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text:
CTET Admit Card 2016
Candidates may Download CTET Sept Exam Hall Ticket 2016 from the official website because it is successfully uploaded by the Central Board of Secondary Education. Candidates may download w CTET Admit Card 2016 by using their registered no.
Central Board of Secondary Education is going to conduct the written exam on two phrases i.e. Paper I & Paper II on 20th September but on different timing. Applicants who want to attend this examination they may get their CTET Admit Card 2016 from the official website or the mentioned link below and bring it at the day of examination.
To Download Hall Ticket for CTET Sept Exam applicants need to enter their registration no and date of birth and hit on submit button. As soon as the hall ticket will open on your PC Screen (It's up to Internet Speed). After getting hall ticket, applicants must keep it safe till the process of recruitment will not finish.
Name of Authority: Central Board of Secondary Education
Test Name: Central Teacher Eligibility Test
Posts Name: Teacher
For Which Class: I to VIII
Date of Examination: 20th September 2016
Hall Ticket on Display: Available
Link to get Status: www.ctet.nic.in
CTET September Exam Hall Ticket 2016
Central Board of Secondary Education will be conducting the 8th Edition of Central Teacher Eligibility Test to hire eligible candidates for teacher posts for classes I to VIII. This test is conducted in two papers, paper-1st is for those candidates who want to select for the primary classes (I-V) teacher and paper-2nd are for the secondary classes (VI- VIII) teacher.
To clear Central Teacher Eligibility Test, aspirants need to do hard work and as we all know very that to get a job for Teacher posts is very respective so applicants don't miss this opportunity and try to crack this examination. If you are looking for CTET September Exam Hall Ticket 2016 then on 4t you may collect this document from the mentioned link below.
Steps to Getting CTET Admit Card 2016
- Firstly aspirants need to open the Official website.
- After that, go to the News section.
- From this section, find the suitable link to download admit card.
- Then Input your registration no and date of birth in the empty box and hit on submit tab.
- After that wait for pages loads.
- After few second, hall ticket will open a new page within few second.
- Check it and save on the desktop.
- Now finally get a hard copy for Exam Use.
Important Dates for 2016
Admit Card Release on
4th September
Date Of Examination
20th September
The paper I
02:00 to 4:30 P.M.
Paper- II
09.30 to 12.00 P.M
Important Link:New: The Admit Card for the CTET Exam is available on official link


text:
I apologize if I've missed this discussion, and failed to search effectively.
We've been using the HelpDesk feature for a couple of weeks and love it thus far. I'm having an issue with a handful of tickets seemingly re-opening on their own.
These tickets were created via the user helpdesk interface. One had a user typo in the email address field, and I'm attributing that one to a bounceback forcing the ticket reopened. The others just reopen with a "reopen" and "No Comment" from the user. The users insist that they've not even checked status of the ticket on the user website, but are getting hammered with closed/reopen notifications in email.
1 Reply
May 3, 2007 at 10:54 UTC
Perhaps check out http:/
I found that thread by browsing the "Help Desk" tagged threads. You can do the same by clicking the "Help Desk" tag located at the bottom of this thread. As the Help Desk is a popular topic, you may have to browse past the first page.


text:
It only takes a minute to get started. Fill out our simple sign up form and login to the site.
This step is elective but will greatly enhance your chances of getting interest from other over 40s members on the site. Write a little about yourself, your hobbies and upload a nice photograph of yourself.
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text:
Don't think about this equilibrium as something "optimal" per se. Think of it as an occurance of strategies in a game where none of the players have a desire to change their strategy given other players strategies. Note well this can be a stupidly large solution concept and needs some refinements.
Pure Nash Equilibria
Mixed Nash Equilbria
Common knowledge is when every one in the games know a peice of knowledge and they know that others know...and they know that the other know etc etc. It sounds crazy but thats what it is.
Payoffs based on their own actions and the actions of others
Knowledge of other players and game
Added Nature here, might be something to it
Strategic Game
Sequential Game
1) Type of Game, Extensive, Normal Form
2) Number of Players
3) Set of Actions
4) Strategies
5) Utility Functions
6) Pay-Off Functions
The matrix style ones. All players move at the same time.
Players move after each other.
Sub-game Perfect Equilibria, Trembling Hand Equilibria, Proper, Evolutionary Stable Equilibrium, Perfect Baysian Equilibria, Cho-Kreps Refinement


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New Braunfels Herald Zeitung (Newspaper) - June 16, 1996, New Braunfels, Texas Bike club members love winding Hill Country reads See Sports, Page 1B. of the Stocking Revue SssPagtftA. New Braunfels l0/22/99 2627 E YANDELL nR Herald-zjeitung SUNDAY SIAO 40 Pages in three sections ■ Sunday, June 16,1996 Serving Comal County for more than 144 years ■ Home of HKATHKR WILLIAMS Vol. 144, No. 155 County courthouse Inside People.... Spots Day Marketplace Birthday wishes from th* HarakUMtung! The New Braunfels Herald-Zeitung extends the following birthday wishes to; Heather WlHlams, Rochelle Rapp, Jertk Salazar, Nancy Kne-upper (Monday), Chad Ken- co Stepped-up child support enforcement floods district clerk's office By DENISE DZIUK Staff Writer Tejano musician David Marez is not the only erne finding himself in trouble with child support payments. The Attorney General's office has stepped up its efforts to make sure divorced fathers help share the financial burden of raising their children. And that increased enforcement is causing a flood of paperwork at the Comal County District Clerk's office. Comal County District Clerk Margaret Herbrich said clerks across the state are being "bombarded" by paperwork from the Texas Attorney General's office in child support cases. "They've been mandated to take a hard line, and that's what they're doing ... I don't think we were ever aware of the number of cases," she said. "It's kind of mind-boggling." The increase in die number of delinquent cases being pursued by the A.G.'s office is reflected in financial figures. The district clerk charges the state from $8 to $45 for various services in helping the state enforce child support judgements. Herbrich said the county bills the A.G.'s office, and is reimbursed for 66 percent of the costs. Herbrich said the reimbursements for January through May of 1996 has tripled from the same period in 1994 to $15,978. Herbrich said more cases are ending up in court, thanks to a new law that went into effect last September. She $15,978 $16,000 $12,000 $9,696 $8,000 $5,150 $4,000 Jan.-May Jan.-May Jan.-May 1994 1995 1996 said the first jury trial for criminal nonpayment of child support in the county was held a few weeks ago. The father was found guilty, and sentencing should take place at the beginning of July. "If he could have proven he was unable to pay, they could have dealt with that," said Herbrich. "(The verdict) does not mean she will get the support." Herbrich said several other men have been indicted, but have not gone to trial. Herbich said there are more than 15,000 child support accounts in the county, including the ones that are paid in full, and her office takes in about 2,500 payments each month. "The tension is there because you feel like you can't breathe," she said. "You just wonder where it's going to end." Herbrich said she expects the num- 'I don't think wo wore over aware of the numbor of cases, lf a kind of mino-Doggiing. — Margaret Herbrich, Comal County Clerk ber of cases to remain high until the state catches up with its backlog of paternity cases. However, even when the state catches up, it will just mean more child support payments for Her-brich's office to take in and process. "It's a continuous flow of paperwork," she said.Veterans thanked for home-grown display of patriotism. See Opinion, Page 4ZSL Chamber needs summer volunteers The Greater New Braunfels Chamber of Commerce needs volunteers to help out in the Visitor Center during the summer. Volunteers are needed weekdays and weekends for three- or four-hour shifts. On weekdays, volunteers assist the staff by compiling brochures and stuffing envelopes, and on weekends they keep the Visitor Center open to greet tourists. lf you want to help out, call Lyndi Moon at 625-2385. Pilots Club gsts off tho ground The first gathering of retired fliers was held in May, with 24 people in attendance. The next meeting will be Tuesday, from 11 a.m. to 1 p.m. at the Senior Citizens Center, 655 Landa St. Suggested luncheon donation is $3.50. Barbocuo and concert slated The Hill Country Chorus will present a concert at the Comal County Senior Citizens Center Tuesday A barbecue dinner will be served at 6:30 p.m., and the concert will start at 7:15 p.m. Tickets are $10 and the money will go to the center's expansion project. Circus Is coming The Shrine Circus is coming to New Braunfels with one performance at the Rodeo Arena, sponsored by the Comal County Sheriff's Posse. The performance is at 7:45 p.m. Friday. Tickets will be sold the day of the performance at the Rodeo Arena box office. HOPE to sponsor collop# workshop The Hispanic Organization for Public Education will hold a workshop for anyone age 18 or older interested in attending college. The meeting is at 7 p.m. Monday at the NBNB Building, 1000 N. Walnut. Guest speaker will be Richard Delgado of San Antonio College Uppor Room opening The Upper Room is a summertime get-together on Wednesday nights from 7 to 11 p.m. for all high school youth of New Braunfels. It will run from this Wednesday to Aug. 7. St. Paul Lutheran Church will host the Upper Room from June 19 to July 10, and First Protestant Church will host it after that. This newspaper is printed on recycled newsprint More Than A Coach All the time he's been teaching thousands of kids to swim, 'Bud' Dallman has been learning a few lessons of his own gy DENISE DZIUK Staff Writer local man has used his experience raising six kids to help him become a model swim coach, and through coaching, has learned even more about being a father. E.E. "Bud" Dallmann, of New Braunfels, it the father of six children—four daughters and two sons. But he is best known as swim coach to two generations of New Braunfels youngsters — more than a coach, a father figure. It was 37 years ago when Dallmann, 76, started the Dolphins swim clubs, which enroll up to 200 children in the summer. He is also the coach of the New Braunfels and Canyon high school swim teams. And he does it all for free, for the children. It is self-discipline, he said, that gets you places in life. And that is what he tried to instill in his children. He said teaching self-discipline and how to have pride in what they do really is not difficult when it is done with compassion. "Showing satisfaction and pride in what they do right gives them the motivation to do more of the same," said Dallmann. The same philosophy of self-discipline, mixed with signs of satisfaction and pride, has helped Dallmann coach thousands of swimmers over the past 37 years. Dallmann said good swimmers need self-discipline. However, there is mote to coaching than discipline. Dallmann said he "doesn't coach swimming," he "coaches swimmers." He said in the process of learning to be great swimmers, they learn skills needed to be successful later in life. "At the end of practice, we have the one-mile swim," said Dallmann. "It builds confidence in knowing you can do it, self-esteem by finishing it, and the stick-to-itiveness to finish the race, whatever it it." He said being a swim coach is logical became swimming played a large part in his life. He said it built up his self-esteem and confidence level, and he can see the same happening in his students. Like any father, he likes to see his kids happy, and said his greatest satisfaction as a coach comes when he helps a student and is repaid with a bright smile or a hug. "What more can a person ask for," he said. For all he has taught his swimmers, they have taught him something in return. Dallmann said that after spending so many years working with children he has learned a lot, and if he knew then what he knows now he would have been a better father. "I would be more involved in what they want to do than in what I would like them to do," said Dallmann. "I would concentrate more on the things that make them happy than on job satisfaction." Dallmann said there is no doubt the he has been somewhat of a role model for his kids when it comes to raising his 17 grandchildren, 19 greatgrandchildren, and I great-great grandchild. He said it is "human nature" for people to follow what they see, "especially if they had good parenting." However, he said he hopes they will learn from his errors. "You hope your children will parent better than you did," he said. Dallmann has basic advice for all parents on this Father's Day—love your children. Push is on to bring YMCA to New Braunfels By ABE LEVY Staff Writer This is a class project that just wouldn't go away. As part of his training in the 1994 Leadership New Braunfels class. Tim Brierty conducted a study looking into whether the community would benefit from a YMCA. Brierty, senior vice president for operations at McKenna Hospital, graduated from the local leadership school, but people kept asking him about the Y project. Although the response was positive, the idea waited in limbo until Brierty decided to make a serious effort to get it off the ground. Brierty and six other community leaders have formed a task force to keep the ball rolling. More than two years after getting started, the class project is up for community consideration at a 7 p.m. hearing Thursday at Memorial Elementary, 1900 S. Walnut Ave. "I'm concerned I'll lose the momentum and hope it won't be a seven-man show anymore, but that people come out of the woodwork to come out and help," Brierty said. At the meeting, the results of a feasibility study will be made public and should offer insight as to whether the idea will take flight. The study's conclusions are based on 35 interviews with community leaders, asking them about their image of a Y, its strengths and weaknesses, whether a Y is needed and whether the economy is ready to support a Y. Preliminary reports indicate a positive response from the study, Brierty said. The bottom line is whether the community is willing to yield $210,000, which will fund the first two years of the project. If the Thursday meeting goes well, a fund drive will take place until July 25 to raise the money, Brierty said. The fund drive would start up again in January if enough money is not raised. The United Way of Comal County paid $7,500 for the study, which First Council, Inc of Dallas, conducted for a discounted price, Brierty said. If enough money comes in, the group can gam a charter that will allow it to take action toward starting community programs. The Y in San Antonio would also help oversee establishing a Y in Comal County. So far the Y's only presence in the area has been an after-school program. Heratd Zeitung photo by MICHAEL DARNALL Driver escapes injury New Braunfels Police Officer John Villarreal looks over the scene of a Friday morning accident. Settle Wood, SO, of Rosenberg, Texas, escaped injury when her recreational vehicle crashed In a field at Highway 46 and Mission Valley Road. See story, Page 2A.For subscription or advertising information, call the Herald-Zeitung at 625-9144. ;
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text:
ITV chiefs have been rapped after thousands of Britain's Got Talent viewers COULDN'T vote by a smartphone app they had bought.
In the first semi-final in May so many people voted that the system couldn't cope and 51 per cent of votes made with the £1.49 app were not processed correctly.
ITV ditched the voting method, told viewers how to get a refund and investigated how to avoid future problems with app voting.
Media regulator Ofcom said ITV was responsible for ensuring all its voting systems were robust. It said: "We were therefore concerned that the application was unable to handle demand when voting opened.
"This meant a significant proportion of viewers who had responded to the programme's invitation to purchase voting credits via the app were unable to use them and that therefore viewers were effectively misled – albeit unintentionally."
ITV said several tests had been carried out in advance to check the technology and blamed a "firewall mis-configuration" at the company organising the voting for them.


text:
Canberra, Jan 11 (ANI): Queensland Premier Anna Bligh has said the death toll from floods in the state might rise "quite dramatically" as rising waters and continuing heavy rain continue to hamper rescue efforts.
According to the Sydney Morning Herald, Bligh's warning came after eight people were confirmed dead and 72 people were reported missing.
"We're hoping and praying that many of those 72 people have gone to safety overnight and will be found safe and well. But given the circumstances we hold very grave concerns for many of those people," Bligh said.
"Many of the people who are stranded or unaccounted for are families and young children and some of those who have lost their lives overnight are young children, including a mother and two children in a vehicle," she added.
The flooding has taken on a new dimension after flooding ravaged the state's south east late Monday, pushing flood waters towards the major city of Brisbane.
Meanwhile, about 200 people have reportedly been evacuated from Forest Hill and Laidley, near Toowoomba. An emergency alert has been issued for flash flooding in the areas, warning residents of rapidly rising water levels and property inundation, posing an immediate danger to residents.
The paper quoted Toowoomba Mayor, Peter Taylor, as saying that there had been "unbelievable damage" to the city.
"It's a real disaster scene where I'm standing at the moment in Russell Street, Toowoomba. There's furniture and furnishings and it's just blown shops away. We have a railway line about 60 or 70 metres suspended in midair and two cars that are virtually unrecognisable that have floated and smashed into the rail," he added.
Queensland has been hit by the worst flooding in decades due to continuing rains since late November 2010, and about 200,00 people are said to have been affected so far. (ANI)


text:
Twenty-Four: The Affair
Andrea's eyes met Keith's in an instant. Who was he to deny the guilt that ran through them? There it hid, though her anxiety was not very veiled.
Keith flicked his hands up to signal her, vaguely but in some way that would be noticed amongst the comedy that he had stood next to. 'Come here', he glared. He watched, furious, as the girl placed her hand upon his arm, and whispered those delights into his ears. With a nod on both sides, Andrea herself stood up, brushing down the skirt that clung like a creeper to her.
It was a mere minute, Keith standing at the side of the theatre, until she was by his side again, red in the face from her travel, mostly likely embarrassed from having to leave the show. Good. Keith was pleased to have some sort of hand over her, at least.
"Thank you, Mr. Connelly," Keith said to the usher with a curt nod. The latter ignored him, peering back at the stage.
Andrea was silent as she pushed her way through to the foyer. Although she once made to go through to the dining hall where the refreshment table was being set up, instead she simply paced about the entrance, her face a strange shade of white.
"What are you doing here, Keith?" she whispered. The hoarse voice matched the petrification.
"I came…to see you," he replied, nodding, wrapping his hands about themselves.
"Me? Keith, you didn't even know that I would be here. I don't understand."
"No, neither do I, that's why I came."
"Your old school," he said, brimming with a new sort of confidence. "I looked it up. It wasn't hard, you know. I hadn't realised it, but you've never told me about yourLansdalelife. Just skirting around it."
Andrea was sent into a wild flurry of gesturing.
"Keep your voice down…"
Hers may have slid to the edge of silence, but Keith refused to play the game that Andrea wanted him to.
"Outside. Now," she hissed, whipping around and marching out of the room.
"Okay, then," he replied with the deathly stillness that wanted to haunt him.
Keith shrugged to the midnight sky, observing the figure of Andrea as she continued to march into the middle of the green that decorated the front of the school. Keith couldn't help but remark to himself how false it was, just like she was.
"You followed me." Her statement came at the heel-turn, Andrea a metre away from him.
He didn't dignify her with a reply.
"You did follow me, didn't you? What is this…?"
"Lucas Gorge works here, doesn't he?" A question for a question; it seemed fitting enough, for her answers would be just as vague, Keith assumed with bitterness.
"Yes, but how do you…?"
"He was the man at our door- or do you not remember, so swept up in the romance?"
"Romance?" Andrea's temper began to grow, judging by the gnashing of her teeth as she spoke.
"Well, what else are you doing here, Andrea?"
"What? What exactly do you mean to imply by those words?"
"Oh, a night out, is it? Another birthday gift, yes?"
"Ha, and you admit to it being another gift!"
"You are twisting my words, Keith!" Andrea let her Ss hiss towards him.
"What else can I do, when you don't tell me?"
"I have my privacy, too, you know!"
"And we're meant to be a partnership, a couple!"
"Well!" Andrea huffed.
"Oh yes?" Keith snarled. "Go on then: say it."
"Don't play with me; don't even dare me, Keith. What is going on?"
"You tell me."
"I have!"
"You didn't tonight. 'Somewhere', don't you remember? This is nowhere,is it?"
"It didn't seem that big a deal to me, Keith."
"What about you?"
"I am no liar; if you refer to the Christine incident, well, that was her fault, and I walked away, didn't I?"
"Still- what about my feelings?" Andrea remarked in a bitter tone.
It was only then that Keith realised the full effect of Christine's presence.
"A strain," he spat. "Your own jealousy thought the worst of me?"
"Exactly," Andrea muttered. She fiddled with something clutched in her hand.
"More lies," he cried. "I came to trust you, but look where it has led me."
His advanced towards her, shaking, ready to clutch her hand.
Once again, Andrea spun, so that it was he who faced the front entrance this time. What a dance indeed. But it still left him without answers. A quick glance to her hands showed Keith that Andrea had, rightly, taken her bag when she had left the theatre.
"Keith!" Andrea yelled. "What are you doing?"
"What are you doing? Who is Lucas and why on earth have you been spending so much time with him?"
"I haven't."
"What is wrong with me that you keep lying? Give me your phone."
"First you follow me, now this? Keith, no!"
But, no matter when she had removed it from her purse, she had it clenched in her white fist. As she went to, covertly, put it away, he nudged her and the device went flying to the floor, right beside Keith's shoes. He knew enough about Andrea to be sure that there would be no key-code.
Keith stared at the amount of flirty messages between the two of them. Kisses in Xs were in every message, even the one from her birthday evening.
"Keith! What-? Give me that. Please!"
Now Keith's own throat was almost too dry to talk.
"You were with Lucas last night," he spluttered.
"That's ridiculous."
"Then why does your phone tell so?"
In the silence, Keith watched the angry confusion on Andrea's face that echoed his own. On the other hand, she had no valid reason to feel such a hatred; right now all Keith could think about was that man who had so casually rested his hand upon Keith's girlfriend's thigh. His eyes had been full of the delicious lust that a male 'home-wrecker' needed for his plans to be a success.
"Are you having an affair?" He brandished the phone in her direction, just out of reach.
"Keith…" Andrea looked like she was about to burst into tears. It was guilt all right.
"And did he plan this from the start? When he arrived? Or was he just checking out your new place. A bedroom of your own, ha! You're no more a straight woman than he is a charmless man. Is that what it was? Oh, Lucas, come and save me from this horrible regime the man has put me under!"
In the light from the edge of the school's theatre, Keith could see the tears.
"Stop it, Keith."
He edged nearer, finally thrusting the phone into her hands.
"Then say it. Tell me- look me truthfully in the eyes- that you love me."
"You're not like this, Keith. This is not you, dear. Please remember your sense."
Sense? Ha, it had vanished when Andrea had stepped out of the door that evening.
"You're avoiding my request."
"Your order," she muttered.
"Excuse me? Who is it between us who sneaks off with another man?"
"It's not like that."
"Then what is it?" he roared, a new strength come upon him now. "Why not me?"
And then the front entrance opened, flooding Andrea's tear-stained face open for all to see. She was wearing ridiculous makeup again. In the distance, Keith caught snippets of woven Shakespeare, plus the occasional clatter of the lifted stage. In the foreground, on the other hand, there came a voice that Keith just wanted to pound to dust.
"Andrea, what's wrong?" Lucas asked, innocence reverberating, spoiling his act. "What's happened?"
Keith felt his cheeks flush and his jaw go solid.
"Lucas," she said, through a clenched jaw, too, "please, leave us be to sort this out."
His hands reached out.
"Is there anything-?"
"No!" Keith leapt forward, blocking his rival from touching Andrea. Though images of knighthood and romantic chivalry sprung to his mind, Keith was determined that this scene would play out differently.
"I'll go…" Lucas lifted his hands in defeat, and turned. At the door again, he added, "Andrea, I'll be in the foyer if you want to talk."
"Yes." She nodded, in spite of Keith's obstruction, his hand thrust onto her shoulder. After a second, just as he had begun to calm, her light voice rang out again:
"Yeah?" The man spun, one hand just about to close the front door. His eyes would not meet Keith's; if they had done, they would only have met the stone-cold fire that Keith was determine to keep in his expression.
"What time is it? The play…?"
"The interval has just finished. The next Act has begun already. I was coming to see if you wanted to come back in. Didn't you see-?"
"We didn't," Keith interjected. "Leave."


text:
At least two people, including a judge, have been killed after a gunman opened fire inside a courthouse in Milan in northern Italy on Thursday, judiciary officials said.
According to several Italian media outlets, the suspect is believed to be a defendant who was in court for a bankruptcy proceeding.
The sound of shots ringing out had caused panic, with lawyers seen fleeing the scene.


text:
ED Magedson – Founder
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Aarons Sales And Lease3636 W Glendale Suite 2 Phoenix, Arizona U.S.A.
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This report was posted on Ripoff Report on 09/29/2008 03:23 PM and is a permanent record located here: http://www.ripoffreport.com/reports/aarons-sales-and-lease/phoenix-arizona-85017/aarons-sales-and-lease-rip-offs-phoenix-arizona-377067. The posting time indicated is Arizona local time. Arizona does not observe daylight savings so the post time may be Mountain or Pacific depending on the time of year.
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text:
Chalet | National Park | #8552
Fantastic Modern Chalet, . Finished to the highest standard , fully insulated, plus double glazing to all windows and french doors Super efficient Log Burner keeps the chalet nice and toasty. This is the premium accommodation in the village ,and for a reasonable cost . All the mod cons,, quality mattress and duvets. AUTOMATED drying room, just flick the switch and all your wet gear will be sweet for next day up the mountain .Very handy to all cafes and pubs. Whakapapa ski field is a 20 minute drive,and Turoa ski field isa 55 minute drive. World famous Tongariro Crossing is a 20 minute drive away, as is the 42nd Traverse which is a must do for cyclists. With TONGARIRO NATIONAL PARK on the door step there are countless beautiful walks available.
Special conditions: MINIMUM 2 nights stay. LINEN - BYO or can be supplied for $15.00 per person per stay.
bedroom 1
1 x Queen bed
bedroom 2
1 x Queen bed
Combined living/sleeping area
2 x Fold-out sofa bed
Tiny Tots room
Other sleeping area
2 x Mattress/Futon/Air bed
*Pricing may vary depending on the dates you choose and the number of guests. Additional charges (extras) and minimum stay criteria may also apply. Service fees may also apply.
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text: Sounds logical to me, but i am prejudiced since I came over to 10mm last year. I like the model 20 but I like the size and feel of the model 29 better. As you know, it is thicker than the 19, but the slide length and grip height is very close to the 19.


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There are schools offering plumbing courses in North Dakota!
Schools Offering Plumbing Programs in North Dakota
Nearby States
Your Favorite Schools
Around 0.0% of North Dakota's graduates graduate from plumbing certificate programs every year. That means an estimated 9 plumbers graduate from North Dakota's 2 plumbing schools each year.
Top Schools
North Dakota State College of Science, which was ranked 77th nationwide in 2010, is the top-ranked school in North Dakota that has a plumbing program. It is located in Wahpeton. 6 students graduated with a certificate in plumbing from North Dakota State College of Science in 2010. North Dakota State College of Science charged in-state students $4,173 in tuition fees per year.
Fort Berthold Community College, which is located in New Town, is the second-ranked school in North Dakota that has a plumbing program. It received a ranking of 92nd in the country in 2010. In 2010, Fort Berthold Community College graduated 0 students from its plumbing program. Tuition at Fort Berthold Community College was $4,210 per year.
If you choose to attend a North Dakota plumbing school, average tuition will be $4,192 per year. However, tuition at your particular institution may range from $4,173 per year to $4,210 per year. The North Dakota plumbing schools with the highest tuition rates in 2010 were:
- Fort Berthold Community College - located in New Town, students are charged $4,210 per year
- North Dakota State College of Science - located in Wahpeton, students are charged $4,173 per year
The following North Dakota plumbing schools had the lowest tuition rates:
- North Dakota State College of Science - located in Wahpeton, students are charged $4,173 per year
- Fort Berthold Community College - located in New Town, students are charged $4,210 per year
A plumbing certificate from a North Dakota school... what next?
The highest percentage of plumbing graduates in North Dakota pursue careers as a plumber. 1,070 plumbers were working in North Dakota in 2010. In North Dakota, the largest numbers of plumbers work in the following counties:
- Clay County - 390 plumbers
- Bottineau County - 290 plumbers
- Burleigh County - 160 plumbers
Projected Growth
The government projects that by 2018, the number of plumbers in the state of North Dakota will grow to 1,230. This would require a 18% growth in the profession.
On average, plumbers earn $46,960 per year. However, North Dakota plumbers earned anywhere in the range from as less than $23,180 per year to more than $74,740 per year in 2010. On average a plumber earns the most in the following North Dakota counties:
- Bottineau County - $57,590 per year
- Polk County - $46,520 per year
- Clay County - $44,510 per year
A plumber in the following counties in North Dakota make the lowest salaries on average:
- Barnes County - $37,880 per year
- Burleigh County - $42,060 per year
- Clay County - $44,510 per year
More Information
For more data regarding a career in plumbing in North Dakota and to compare salaries with various related fields such as automotive or plumbing, take a look at the graphs and charts below.
Here are the different levels of study available for you to explore.
- Certificate in Plumbing in North Dakota
Want to study at your own time and pace?
Consider Online Schools as a great alternative flexible option to earn a degree!View Online Schools
Featured Online Schools
Kaplan University
|Acceptance Rate
|Student Population
|6,540 miles from location
|North Dakota State College of Science
|6,800 miles from location
|Fort Berthold Community College
|New Town
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Curious what studying Plumbing gets you?
Check out the different options and how they're looking in North Dakota
|Employment Number
|Avg Salary
|Job Growth (past 5 yrs)
|Plumbers, Pipefitters, and Steamfitters +
Got your degree? Time to find a job!
Below are plumbing related jobs in North Dakota


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Destination Wealth Management is a rapidly growing Wealth Management firm with an opening for a Service Wealth Advisor. This is an opportunity for an intelligent, positive and responsible person with high initiative, strong communication skills, and a desire to learn.
Destination Wealth Management is a values based financial services firm with a – more... friendly, open environment where a highly motivated, independent work style is rewarded through personal growth and professional advancement. – less


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|Nexuiz - Launch Trailer
The CryEngine 3 downloadable shooter gets its very own launch trailer.
Mar 3, 2012
Duration: 01:07
Views: 0
|Nexuiz - Dynamic Mutators Trailer
Why not check out Nexuiz's dynamic mutator trailer. Go on, it has guns in it!
Feb 24, 2012
Duration: 01:19
Views: 17
|Nexuiz Announcement Trailer
It's a Nexuiz announcement trailer… wait, wasn't this announced already? Well, consider it reannounced.
Feb 23, 2012
Duration: 01:13
Views: 13
|Nexuiz Gameplay Trailer
The CryEngine 3.0 downloadable shooter gets its very own gameplay trailer.
Jul 3, 2011
Duration: 01:07
Views: 28
|You need to log in or register to use MyAchievements.
|This Week on Xbox Live [XBLA and DotW]
|Feb 28, 2012
|Nexuiz Hits Tomorrow - Here's a Wubby Launch Trailer
|Feb 28, 2012
|Nexulz Finally Coming Next Year, Debut Trailer Fulla Sci-Fi Booms
|Dec 13, 2011
|Nexuiz Trailer Shows a Minute of CryEngine-Powered Shootery
|Sep 22, 2010
|Illfonic Using CryEngine 3 In Upcoming XBLA FPS
|Jul 13, 2010
|You need to log in or register to rate games.
User Score is based on 20 user ratings.


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Hanting Hotel Chongqing Nanping Wanda shop is located on the South Bank area on the 7th Avenue South City. The hotel is located in Nanping most prosperous, bustling business district, the hotel received before Nanping Wanda Plaza, right with Star Times Square, leisure and entertainment. Hanting Exp...
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text:
|645 sq. ft.
|Property type
|Minimum Stay
|3 nights
1st floor 60 sq metre , 1 bedroom (double bed measuring 150 x 200 cm) with separate bathroom and open plan living area this is a great base for visiting the area. Fully equipped and fitted kitchen, dining table can seat 6 and comfortable sofa and chair make relaxing here a treat. Situated behind the 16th century church, the apartment is furnished in a mix of antique and contemporary pieces. The bathroom is fully tiled with a walk-in shower, vanity basin and a washing machine in the cupboard. All bed linen (Egyptian cotton) and towels supplied for your visit. The separate bedroom has a large double bed and a wardrobe for clothing so ample place to unpack. Free wifi connection but no TV!
We have stayed in 6 VRBO's in France and Italy over the last two years, and this one is our favorite. The apartment itself is beautifully decorated, and has a lot of extras we just haven't seen elsewhere: picnic blanket, straw hats and basket for shopping at the market, plus a fully equipped kitchen which would be ideal for a long term stay or just an enthusiastic cook. The apartment is located on the second floor (no lift) and stays cool even when the temps neared 90. We did not find the church bells bothersome at all, as another reviewer had mentioned, but we also kept the windows closed until sunset.
The free parking is a short walk away (3 mins); it's a public lot. We never had trouble finding a spot even at 1pm on Sunday (market day). If you have lots of luggage, you could pull right in front of the apartment to unload. We found it easier to simply walk with our rolling style bags.
Sandi, the owner, meets you at the apartment, is very friendly and helpful, and has a wealth of knowledge of the area. She provided us with restaurant and winery recommendations which made our stay even better.
I would highly recommend this town and specifically this apartment for either a short- or long-term stay in Provence.
Stunning apartment in beautiful location. Highly recommended
The owner, Sandi, was very delightful and helpful. The apartment is clean and large; the walk up of one flight is easy. Sandi provisioned the apartment with ground coffee and a bottle of Rose, both very much appreciated. The apartment is literally 10-15 ft. from the village church, which as one might expect, on the hour and half hour rings its bells to signal the time. Not a huge draw back by any stretch, but if the apartment windows are open, which we did each day and evening, the bells can be a little annoying, but certainly there is some charm to the bells and not a reason to skip this location. From a location standpoint, you will have access to everything in the village center ( shops and restaurants) within a 5-7 minute walk. A large public parking lot, which is the place to park, is within a 5 minute walk and easy access to the apartment with luggage ( even if your girlfriend over-packed and you serve as her Sherpa, as I did). I highly recommend Sandi's apartment!
We had a fantastic time in this amazing flat. It's open and spacious and clean, very tastefully decorated, the back windows open onto a small branch of the river and the church, and it can't be in a better location. The space has just been renovated, and combines modern comforts (kitchen, bathroom, etc.) with beautiful old French furniture and decor, undoubtedly sourced from all the local brocantes that are found in town.
There are plenty of shops and bakeries and restaurant/bars only minutes from the front door so we weren't lacking for anything during our stay. While only steps away from the main square near the church, the apartment is quiet and allows for a relaxing evening after a day of exploring the area. The little village is adorable and is great for either walking around and shopping for antiques, or just sitting riverside with a book and glass of rosé.
Sandi was very helpful during the booking process and leading up to our stay. She was available by email and phone and met us at the apartment to show us around and gave us some tips for the area. We appreciated the welcome and would definitely recommend this apartment to anyone planning a trip to Provence.
Sérieux, confort, générosité, proprete, tout était au rendez vous. Une adresse à retenir ou le mot hospitalité revêt tout son sens. Encore une fois merci à Sandy et Patrick.
My wife and I had an amazing stay in this beautiful apartment in L'Isle-sur-la-Sorgue. Sandi met us at the train station and we walked through the beautiful town to the apartment. The apartment had been recently renovated and, without exaggeration, it was perfect. It was in the heart of the town and within walking distance of everything. From the incredibly well equipped kitchen, the beautiful bathroom, the amazing antiques and to the fine sheets on the bed, there was nothing that was missing. The property was very clean and Sandi was always on hand to provide us with any information we required about favorite restaurants, places to visit and anything else we might be needing. We truly had a wonderful visit in L'Isle-sur-la-Sorgue. The Sunday market was a highlight, as well as visiting the many antique stores and renting bikes to tour the countryside. There are more than enough great restaurants to choose from, as well as an abundance of great French patisseries/ coffee/gelato/ wine bars to keep you well fed and hydrated. We would highly recommend Sand's apartment and hope to return some day. Very fond memories! Thank you Sandi.
Perfect base for exploring both the town and it's markets and antique shops as well as the surrounding areas of the Luberon
|Rate Period
|Weekend Night
|Monthly *
Sep 23 2017 - Oct 14 2017
3 night minimum stay
My Standard Rate
3 night minimum stay
|No additional mandatory fees
|Refundable damage deposit
1. Please note that damage deposits will be refunded after your stay via the HolidayRent payment facility. We notify them about the refund after your departure and they will automatically refund your account. This should take up to 7 working days.
2. While we do not charge for pets, we do expect owners to respect our property and keep muddy paws, dog hair and general doggy ness to a minimum and ask that the occupants Hoover before departure. Pets are not allowed on the furniture!
* Approximate monthly rate. Actual rate will depend on the days of the month you stay.


text:
At the tenth China Joy in Shanghai, mobile games drew a lot of attention from developers and platform providers. Providers tried to find the ideal teams and products, while developers sought effective operating platforms. Most of them focused on the Android operating system.
Gameloft was one such participant at China Joy, though the mobile game developer from France didn't set up its own exhibition booth. Instead, the company chose to bond itself to its new cooperation partner UC.
Chen XunDa, Business President of Gameloft China, explained that, "there are not many mobile platforms with game operating experience; our main task is to find a suitable platform for our games."
However, the chaotic situation in the domestic Android market presents game developers with many problems. There is no unified standard for Android, and the management is out of order; in addition, the skill levels of Android platforms vary. Therefore, Gameloft is rather careful when it comes to choosing a platform partner.
Lack of High-Quality Mobile Games in Domestic Android Market
Though China's mobile Internet is growing fast, there is a desperate need for high-quality mobile games. However, few people are willing to pay for the games. According to a survey by research company Newzoo in May, American users pay five times for iOS games than Android games, and in Britain sixteen times. Though there is no data about the situation in China, it can be inferred that the outcome may not be so positive given that Chinese users haven't yet formed mature consumer habits.
"Though there's no huge bubble in the Android industry, a problem exists in innovation. Making fast money has been part of the main stream, which crowds out quality-based products," says entrepreneur Wu Bin to TechWeb.
Ni XianLe, CEO of Feiliu, believes hardware is one of the many reasons that explain the lack of high-quality games for Android. "Many big games with high-quality cannot run on low-end Android platforms, and users won't pay for those just so-so games. That's why Android mobile games are struggling." In addition, the payment channels for Android are much worse than that of iOS. Users often give up halfway when trying to pay for a game.
Wang Yone, CEO of DeNA China, stresses that the quality of games is fundamental to brand value. High-quality users and developers will be attracted to high-quality games. For teams from overseas, the urgent task is not to make profit, but to open the market and build their brands.
Although with many limitations, mobile games are expected to have a bright future.
During China Joy, the China Gaming Working Committee cooperated with IDC by publishing the China Game Industry Report. According to the report, there were 78 million mobile game users in the first half of 2012, a 70.9% increase from that of 2011. Additionally, this was expected to reach 98 million by the end of this year. Meanwhile, the income of China mobile game was 1.26 billion yuan, a 54.4% increase to that of 2011.
"I believe the situation for the Android platform will improve a lot with the hardware and the 3G network equipment. Low-quality products may be eliminated by the market, and it will be a matter of time before PC online game giants enter the mobile game industry. It will be a time for real excellent games." Ni XianLe said.
Translated from the Chinese original by Stella Wang (Netease from TechWeb)
Edited by Matt Johnson


text:
Great Cleaning Services
Reasons to Hire a Commercial Cleaning Service
As we enter a shop, restaurant, office or any type of business establishment, our instant expectation is that it would be clean. At the same time, a manager or business owner would probably have this matter at the bottom of his priority list, considering he has to attend board meetings to attend, meet clients, interview a job applicant, etc. This alone is already pressing a reason enough to hire a commercial cleaning company. Need more reasons? Read below:
Making a Great First Impression on Clients and Would-be Clients
First impressions don't always last forever, but they definitely make a hug difference for most people. On top of that, displeased customers may think the less than tidy facilities as a reflection of how much care the business puts into the quality of its product or service, causing them to take their business someplace else. Indeed, if the business can't even help its own property, how can it help its client? To put it simply, cleanliness is any business' first chance at impressing and wining a client. Read more about this by visiting our site.
In particular cases, such lost customers could even share their negative experience with family and friends, or worse, with the world online. This scenario can easily become PR hell, especially if the business belongs to an industry that requires cleanliness, such as a restaurant.
Health Issue Prevention
Dust can collect in a neglected workplace pretty fast. Employees with allergies or breathing issues may suffer as a result. As prevention is always more effective than cure, it's far better to ensure that these health problems are kept from occurring, instead of having to cope with them when they do. Check this out: http://www.huffingtonpost.com/2014/08/14/home-cleaning-services-what-to-know_n_5660048.html.
Maintaining High Staff Productivity and Satisfaction
Employees work better when their surroundings are clean, but like their managers, office cleanliness is often the last thing they think of. The best way to end such issues without adding burden on anybody is to simply hire people for this specific purpose. Moreover, working with a commercial cleaning company from http://syracusejanitorialservices.com/ is a way of telling employees that management cares about their well-being, hence increasing their satisfaction and boosting their morale.
Cleaning Expertise, Plain and Simple
Undoubtedly, businesses can hire an in-house cleaning staff if they want to, but a commercial cleaning service will provide an additional scale and expertise benefit that an organization's middle managers may not. Let the specialists take care of their cleaning staff, handle scheduling of activities, and procure essential cleaning equipment. You do have to pay a price but it will be well worth the convenience that a good cleaning company can provide.
Prior to hiring a commercial cleaning service, you need to realize that there can be significant differences in the service quality and costs that come with different providers. You have to do your homework to ensure that you hire a company that will actually be an asset to you.


text:
You hear it all the time. You hear it from your parents, you hear it on the news, you hear it on radios, and you hear it from your teachers.
But I didn't think it would ever happen to me.
How would it happen to me? I had the greatest friends and caring parents; these people who cares about me. People who wouldn't let anything bad happen to me.
But it had.
I'm leaving.


text:
Online appointment scheduling software. Clients schedule appointments, pay, and complete intake forms online 24/7. Free signup!
The Easiest Way To Take Bookings Online. Let people book fixed length slots straight into your Google Calendar.
Signup for free and start accepting appointments online in minutes. Manage multiple locations, schedules, calendars, payments, agreements, promotions and more.


text:
Discussion: Should Tampa Bay Re-Address Their Goaltending?
View Single Post
Yzlamic Preacher*
Believes in Yzergod
Join Date: Feb 2012
Location: Vancouver BC
Posts: 7,216
vCash: 500
Originally Posted by
Still All In
First off, if you knew what you were talking about you would see that the team plays exactly the same in front of Garon, Desjardins, and Lindback. Garon kept them in plenty of games and build plenty of confidence to win a game - the truth is, the team can't get out of the ****ing defensive zone to save its life. The offense managed to muster TWELVE SHOTS AGAINST FLORIDA. I'm sorry Florida fans, but against that lineup with Goc as your top center, and half of your AHL team up, its downright ****ing absurd that they couldn't even manage 15 shots against that team.
The only players who have been able to move the puck have been Stamkos and the kids just called up from Syracuse. Its not goaltending. Its stupidity and poor defensive play.
This man here speaks the truth.
It is embarrassing watching them chase the puck around like a bunch of kids. D is the main problem. Goalie stats would go up if the D would help out every now and then.
Yzlamic Preacher*
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text:
Ihubwebsolutions.com is a 1 year old domain, situated in United States. The domain is linked to the IP address 18.104.22.168 which is provided by the hosting company Alchemy Communications, Inc..
It was registered by BABATUNDE OLANIYI , who can be reached at . The site is owned by iHub Web Solutions. Registration details show that it was registered on 07 Jan 2016 through web4africa inc and will expire on 07 Jan 2017.
The site returns a status code of 200. The site is being served through Microsoft-IIS/8.5.