text:
View photos by Brett Delmage of the sculpture launch and performance
Two Ottawa musicians unveiled a sculpture that sings in an Ottawa city park on Saturday.
Jesse Stewart and Matt Edwards created The Listening Tree in St. Luke's Park, on the north-east corner of Gladstone and Elgin. It's a 5-metre-high structure of stainless steel tubes which acts as a transition and gateway to the park. The individual tubes echo the stainless steel traffic signal poles on the adjacent sidewalk, while their combined form resembles the canopy of large trees in the park.
Most importantly, this sculpture creates sound – but only when the wind is in the correct direction. Several of the tubes have carefully tuned slots in them which will channel the wind when it comes from the south or west – but most strongly from the southwest, when gusts blow up both Elgin and Gladstone. The result: a series of shifting tones.
"We thought it would be nice to have something that would draw people in a little closer so they could have a more intimate experience with [the park], and we decided to do that through sound," Stewart said.
But not all the time. "It's not singing today, unfortunately. The wind is not blowing in the correct direction for that to happen, but, actually, we think one of the special things that can happen with this piece is that it's not always singing. You have to be here at a specific time. And so the experience is tied to that time," Edwards told the audience of local residents, jazz lovers, and city staff and politicians.
"It's not supposed to be always active. It's just supposed to be once in a while, so the neighbours don't complain, but other neighbours get to enjoy it," said local city councillor Catherine McKenney. When McKenney asked who had heard it during the ceremonies, several members of the audience put their hands up to indicate they had heard the sculpture singing since it had been installed a month before.
When Edwards was recently adding a protective layer of wax to the sculpture, he related, a man came up to him and said, "This amazing thing happened the other day. I came here and I heard it singing! It was a bit of a windy day, and I didn't realize that was going to happen. I've never heard anything like it."
Stewart said they hoped the sculpture might allow people "to experience a sense of discovery – that they might be here and all of the sudden it will start singing."
Saturday at 1 p.m. was the official opening. Stewart and Edwards played an short concert to start the ceremony, producing intimate, improvised music on two handpans, a drone-producing Shruti box, an accordion, a bamboo flute, and a frame drum.
Read more: Two musicians make their sculpture sing in an Ottawa park
John Stetch
Steinway Piano Gallery, Ottawa
Thursday, September 22, 2016 – 7 p.m.
View photos by Brett Delmage of this performance
For his current solo piano tour across Canada, John Stetch has reached forward and backwards, to his own roots in music and to a rethinking of the well-known classical repertoire. And the result, at his first tour stop in Ottawa, was a dynamic and engrossing hour of music.
Although he's a jazz pianist, the pieces Stetch played Thursday weren't drawn from the standard repertoire. That's a deliberate decision, as he told the audience. He's been to jam sessions in New York City, where he currently lives, and heard other pianists play standards – all too similarly to the way he would.
So he's creating his own sound by playing music other jazz pianists don't: his reinterpretations of classical concertos and sonatas; take-offs on TV theme songs; and music inspired by his Ukrainian-Canadian heritage.
Stetch is originally from Edmonton, and one of his earlier albums was called Ukrainianism [2002]. He played several pieces from that album, based on folk melodies and on Ukrainian history. He also drew from his 2013 Juno-nominated Off With the Cuffs album, in which he took well-known classical compositions by Mozart, Shostakovich, Chopin, and Bach, stripped them back to their roots and reinvigorated them.
Read more: John Stetch dramatically mixes folksong, classical, and TV themes into dynamic jazz
Samba, bossa nova, Antonio Carlos Jobim: that's Brazilian music to most people. But there's lots of interesting and appealing music from that country rarely heard here.
At GigSpace on Saturday, Rachel Beausoleil will introduce a much broader picture of Brazilian music to Ottawa.
The Ottawa vocalist has been studying "Música Popular Brasileira" (MPB) for the last five years. She's now writing her PhD thesis about this music, which includes most of the genres that Canadians think of as Brazilian jazz. During three extended trips to Brazil, she's taken classes from master vocalists, attended conferences, and performed with musicians there.
At Saturday's concert, she and her group, Sol da Capital, will present songs by many composers covering the full range of these styles – from ballads to bossa nova, from music written a century ago to modern songs. What these songs have in common is a dedication to quality; rhythmic, harmonic, lyric, and melodic richness is insisted on in MPB, Beausoleil says.
Sol da Capital started when Beausoleil met Brazilian guitarist Evandro Gracelli, who spent a very busy two years in Ottawa, performing and working with many local musicians. During his stay in 2010-11, they formed the group to perform Brazilian music and their own compositions. They've kept up the connection, even when separated by 8000 km, and Beausoleil has continued performing in Ottawa with local musicians familiar with Brazilian music.
Read more: Rachel Beausoleil shares the Brazilian popular music you don't know
Marianne Trudel Quartet with Ingrid Jensen
Guelph Jazz Festival
River Run Centre, Co-operators Hall
Thursday, September 15, 2016 – 7:30 p.m.
Marianne Trudel and Ingrid Jensen
Guelph Jazz Festival Colloquium
University of Guelph
Friday, September 16, 2016 – 9 a.m.
Marianne Trudel wasn't going to let anything stop her getting to the Guelph Jazz Festival this year.
The Montreal jazz pianist, composer, and improviser suffered a serious concussion this summer, and hadn't played the piano for two months – only starting again 12 days before the festival. Her doctor had recommended she not perform.
But as a long-time performer at Guelph, she did not want to miss the last festival to be curated by artistic director Ajay Heble. "This is my favourite festival in the country," she told the audience at her Thursday night concert, "and Ajay is a very, very special person, close to my heart. I think he did a merveilleux with this festival, and it's something special to be here for his last show."
For this concert, she was accompanied by three stalwarts of the Montreal jazz scene: Jim Doxas on drums, Rémi-Jean Leblanc on double bass, and Jonathan Stewart on tenor and soprano sax – plus trumpeter Ingrid Jensen (formerly of BC, now of Queens, NY). They performed six pieces from Trudel's most recent CD, La Vie Commence Ici [2014], all originals of considerable sweep and richness.
The theme of the album is the ability to be fully present in the moment – an ability which Trudel contends many of us have lost. For many years, she said, she was the only musician in Montreal without an iPhone, and getting one, after considerable peer pressure, was her "worst mistake ever".
Trudel was very much present at this concert. Given the vibrancy of her performance, you would not have known she had been ill.
Read more: Marianne Trudel pays a rich tribute to Guelph Jazz Festival founder
Listening to clarinetist François Houle, you hear a man endlessly fascinated by the myriad possibilities in music. His enthusiasm for his many different projects – even involving a mysterious hum – bubbles over as he talks.
When OttawaJazzScene.ca interviewed him over the phone this week, he got so involved in our conversation that when he was stung by a wasp while walking he ignored the pain and kept on talking.
Houle is an wide-ranging innovator on the clarinet, taking it to places ranging from free improvisation to classical to new music to world music to melodic jazz, and even as a first-call musician for indie rock artists like Matthew Good. He has been listed several times by Downbeat magazine's Critics' Poll and Reader's Poll as a "Talent Deserving Wider Recognition" and "Rising Star". His more than 20 recordings have earned multiple Juno Award and West Coast Music Award nominations. His performances with French pianist Benoit Delbecq were a highlight of the 2012 Ottawa Jazz Festival.
This week, he is on tour in Ontario and Quebec. He performs on Friday and Saturday in two featured concerts at the Guelph Jazz Festival. He'll also play in Ottawa, Toronto, Hamilton, and Montreal. He's playing a solo concert in Guelph;his other shows are in a trio with two fellow Vancouver musicians – guitarist Gordon Grdina and drummer Kenton Loewen.
They're long-time friends: "We've been working together as a group and in various projects for the last ten years. These guys are my brothers on the scene here. They're my go-to collaborators."
Grdina is a Juno-winning composer and musician, who mixes mainstream jazz, free-form improvisation and classical Arabic music, as well as rock and punk. Loewen plays improvised and rock music, including with an anarchist punk band, an art pop group Mother Mother, and Tanya Tagaq.
Read more: François Houle excited about new projects, long-time collaborations
For François Houle, it's always been about the clarinet, starting from when he was 7 years old.
Unlike most other clarinetists, he doesn't double on saxophone, or even play the bass clarinet. He has regular B-flat, A, and E-flat clarinets, and that's it.
He was first introduced to the instrument through his father's big band LPs. Records by Benny Goodman, Artie Shaw, and Woody Herman were often heard in their house – and they all played clarinet.
"And so I just got that sound in my head. One day when I was 7 years old, a cousin showed up and he had started the band program at school. He had his clarinet, and he said, 'Oh I really hate it! I don't want to play it,' and he left his clarinet at my place. And so I started tooting on it, just out of curiosity, and I just basically fell in love with the instrument. And having that sound of that music from the 30s and 40s and 50s in my head, I just started taking lessons and never looked back."
"That was it. I was hooked from the get-go."
When Houle was studying for his Masters in classical clarinet at Yale University, he got to meet Benny Goodman in person. "He came to do a fundraiser with his big band and I got to hang out with him for a few days – not just hearing him live but actually getting to hang out with him. That was pretty special!"
"He was already an old man, a bit grouchy, but very generous with his time and talking to us, the students about his career and his life, and his approach to the clarinet and all that. That was very informative and very inspiring."
Betty Ann Bryanton Presents Sideways Bend Reprise
Les Brasseurs du Temps, Gatineau
Saturday, September 10, 2016 – 7:30 p.m.
View photos by Brett Delmage of this performance
Like many jazz fans, Ottawa vocalist Betty Ann Bryanton prefers the night to the morning – and figures she should be able to sleep in on a Saturday! But the City of Ottawa allows construction to start at 7 a.m. weekdays and Saturdays. Over the last 18 months, with three different large buildings going up in her neighbourhood, she's heard far too many loud beeps and bangs at times she'd rather be sleeping.
At her Sideways Bend show on Saturday, she took revenge – in song.
"The Noisy Blues" was a fast-paced blues which she wrote one morning when she was woken up, again. She and her band played it with an edge, and added beeping, barking, bird calls, and other raucous noises to demonstrate exactly how annoying the noise really was. With lots of energy and even some scatting, it was a performance that grabbed the audience and received strong applause.
But it was only one of the highlights in a well-tuned performance of jazz vocal pieces which Bryanton organized. After a sold-out premiere at GigSpace last May, this was the second time she had presented the material. This reprise show also sold out, with the lower room of Les Brasseurs du Temps in downtown Gatineau completely packed.
In two sets, each more than an hour long, Bryanton performed songs from across the 20th century, ranging from ballads to blues to Latin to upbeat jazz numbers. She had spent a year preparing the original show, and this clearly showed in its professionalism and smoothness. And with Pierre Monfils on guitar, Howard Tweddle on electric and double bass, Lu Frattaroli on drums, David R. Miller on keyboards, and Dmitry Egunov on soprano and tenor sax, she had a good local band which was clearly comfortable with the music.
Read more: Betty Ann Bryanton takes her musical revenge, to a happy full house
Roddy Ellias and Megan Jerome with guest Ed Lister at Irene's Pub
Sunday, September 4, 2016 – 9:30 p.m.
View photos by Brett Delmage of this performance
OttawaJazzScene.ca chose this show as our jazz pick of the week – and we're glad we did!
Guitarist Roddy Ellias and vocalist Megan Jerome created a zone of beauty and intimacy Sunday night at Irene's, at the first of four weekly shows they're performing there this month.
Together with guest Ed Lister on trumpet and flugelhorn, they combined originals by both of them with jazz standards in two flowing sets. It was a quieter show than most Sunday sessions at Irene's, but their audience was intent and almost completely silent, and applauded generously throughout. (The same could not be said for the five-some playing pool at the back of the room, but they eventually did quiet down and left by the start of the second set.)
Ellias and Jerome have performed together in larger ensembles, but this is the first time they've performed as a duo. Jerome told the audience "We're just trying things out, doing things other than what we normally do". Ellias has often played standards, particularly in duos with other guitarists, but he hadn't performed Jerome's songs before; Jerome primarily plays her own material, and doesn't often play standards or Ellias' compositions. Lister's own bands, like the Chocolate Hot Pockets and ERU-ERA, are much more hard-hitting and loud, although he also performs in quieter ensembles.
Read more: Roddy Ellias and Megan Jerome create quiet beauty in a new collaboration at Irene's
Updated September 8
Jazz. Improvisation. Pushing the edge. The Guelph Jazz Festival has always had a very clear idea of what type of music it wants to present and what it's trying to promote.
Much of that is due to the festival's founder, musician and academic Ajay Heble, who has brought a deep love of jazz and an intellectual approach to improvisation to the festival. But after 23 years, Heble is retiring as the festival's artistic director.
|Ajay Heble introduces the 2013 Guelph Jazz Festival photos ©Brett Delmage
The 2016 festival, which runs from September 14 to 18, will be the last he organizes – and he's brought back many festival favourites to perform.
From Vancouver: clarinetist François Houle, guitarist/oud player Gord Grdina, and drummer Kenton Loewen. From Montreal: pianist Marianne Trudel, saxophonist Jean Dérôme, and Esmerine. From the Toronto area: saxophonist/flautist Jane Bunnett, baritone saxophonist David Mott, reed player Peter Lutek, cellist Matt Brubeck, guitarist Kevin Breit, tabla player Ravi Naimpally, banjoist Tim Posgate, and guitarist Neil Hendry. From Ottawa: percussionist Jesse Stewart and violinist William Lamoureux.
From California: pianist Myra Melford. From Chicago: percussionist Hamid Drake, trumpeter Rob Mazurek, saxophonist Ernest Dawkins. From Philadelphia: drummer Chad Taylor. From NYC: trumpeter Ingrid Jensen, pianist Amina Claudine Myers, tuba player Howard Johnson, and pianist David Virelles.
Some of the music they play will look back: there will be two tributes to famous free jazz musicians, and one concert which will remix performances from previous Guelph festivals.
Others will expand possibilities, with performances as diverse as DJ/scratch artist Kid Koala, to the Asiko Afrobeat Ensemble, to the "heavy-handed" FreePunk of Peregrine Falls.
But the core of the festival remains improvised jazz. It has similarities to the Ottawa Jazz Festival's Improv Invitational series – ranging from melodic to highly avant-garde – but on a much larger scale.
Read more: Musical friends return to 2016 Guelph Jazz Festival to celebrate founder's last year
Think "September Song", and you'll have a good idea of what's happening in jazz and improvised music in Ottawa-Gatineau. It's a month to hear jazz vocals – and the start of a new jazz season in which you can hear award-winning vocalists.
Sign up to our JazzScene newsletter to get a full listing of all the jazz and improvised music events within 100 km of Parliament Hill in your inbox every week. You can also check our list of Ottawa-Gatineau-area jazz clubs.
Of course, there's still lots of opportunities to hear mainstream jazz and the avant-garde. But this fall, the big names will include Diana Krall, Emilie-Claire Barlow, Bet.e and Stef, Tanya Tagaq, and Jane Bunnett and Maqueque.
In September, you can hear the human voice celebrated in jazz in many different forms, from ballads to blues to Latin, with shows by the Nylons, Bet.e and Stef, The Juliet Singers, Diane Nalini, Kimberley Beyea, Nicole Ratté, Betty Ann Bryanton, Rachel Beausoleil, Megan Jerome, Anne Lewis, Peter Liu, Steve Berndt with the Jivewires, Hélène Knoerr, Rachelle Behrens, and Caroline Cook.
OttawaJazzScene.ca's September jazz highlights are brought to you by you, our readers. We greatly appreciated reader donations which make it possible for OttawaJazzScene.ca to continue serving the jazz community every day this past season.
Please support our continued publishing in the 2016-17 season with your donation.
Conjunction: The Gryphon Trio with Scott Good, Dafnis Prieto, and Roberto Occhipinti
Chamberfest: Chamberfringe series
La Nouvelle Scène
Friday, July 29, 2016 - 10 p.m.
Dafnis Prieto and Max Pollak
Chamberfest: Siskind Snapshots
Dominion Chalmers United Church
Tuesday, July 26, 2016 - 5:45 p.m.
View photos by Brett Delmage of this performance
Cuban-born drummer Dafnis Prieto is best known for leading Latin jazz bands and collaborating with the cream of the NYC avant-garde jazz scene. Roberto Occhipinti is a prominent jazz bassist and bandleader in Toronto. Scott Good has played trombone with many Canadian jazz musicians.
Did you realize that each of them also composes and performs chamber music?
In one of the most fascinating concerts I've heard this year, these three musicians collaborated with the Gryphon Trio at Chamberfest. In a 90-minute show, they presented four pieces which crossed back and forth between jazz and classical music, building on the strengths of both and ending up with beautiful music.
The Gryphon Trio – Roman Borys on cello, Annalee Patipatanakoon on violin, and James Parker on piano – was a natural partner for this endeavour. The trio may be best celebrated for its interpretations of works by Beethoven and Schubert, but it has also consistently expanded its range outside the standard chamber repertoire, many times together with Occhipinti. Borys is also Chamberfest's artistic director, and has made a point of programming many jazz and jazz-crossover concerts in its late-night Chamberfringe series.
Read more: Conjunction: three jazz and three classical musicians make music that sings (review)
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(The third book in the Blood & Sex series)
A novel by Angela Cameron
In the third book of Angela Cameron's steamy trilogy about a vampire mafia, we discover Blane's hidden passions and struggle to succeed within the vampire hierarchy. We get glimpses into Michael and Tori's established relationship, and learn more about the opportunities and threats that the vampiro faces as they journey to Venice. Will the Alleanza survive the modern pressures of the vampire cosca? Will Blane be able to break through the guarded reserve of Christiana, the beautiful woman the vampire leader has sent to educate the newest vampires? Or will her sense of duty be stronger than the passion that threatens to sweep her away?
Don't miss this exciting continuation of the series Romance Junkies named a "debut that rocks"!
Don't miss this exciting continuation of the series Romance Junkies named a "debut that rocks"!
Used availability for Angela Cameron's Blane
See all available used copies of this book at Abebooks UK or Abebooks US
Paperback Editions
November 2010 : USA Paperback
|Title: Blood & Sex: Blane: A Ravenous Romance (Ravenous Romances)
Author(s): Angela Cameron
ISBN: 1-59003-206-3 / 978-1-59003-206-0 (USA edition)
Publisher: Red Silk Editions
Availability: Amazon Amazon UK Amazon CA
Genre Pages

subset: commoncrawl


text:
The Lullabye Tree
And this was where she let go. This is the place where she gave up her spirit. He walked around the tree. He'd never noticed how really large it was.
In fact, he hadn't really noticed anything about her, their life, all the times she backed him and, never complained.
He sat on the large root, staring out into space. She'd never asked for much. How many birthdays had he missed? How many anniversaries had he begged off, how many excuses?
As if the way he had treated her, taken her for granted wasn't enough, all the women.. last but not least, the child.. She'd been eighteen still, he was old enough to be her father.. not true, more like grandfather.
Tears ran unabated, he felt as if his heart were going to burst.. He couldn't apologize, he couldn't put his arms around her and tell her, he truly had loved her, but.... maybe... He stood, wrapped his arms around the big tree, he cried, wailed, screamed... begged..
The tree vibrated, it's branches moved ever so slightly, a leaf touched his face and, he heard the song...
don't you cry
go to sleep my little baby
"No good dog.. this was too good for him, too peaceful, he should have been drawn and quartered..burn in hell!"


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Ergot (horse anatomy)
The ergot is a small callosity on the underside of the fetlock of a horse or other equine. Some equines have them on all four fetlocks; others have few or no detectable ergots. In horses, the ergot varies from very small to the size of a pea or bean, larger ergots occurring in horses with "feather" - long hairs on the lower legs. In some other equines, the ergot can be as much as 1.5 inches in diameter.[1]
Ergot comes from the French word for rooster's spur.[2]
Like the chestnut, the ergot is thought to be a vestige of some part of the ancestral foot of the multi-toed Equidae, the ergot corresponding to the sole pad of other extant members of Perissodactyla, such as the tapir and rhinoceros.[1] Unlike the chestnut, which in the same individual may be large on the forelegs and smaller or even absent on the hindlegs, the ergot is of roughly equal size on all four legs.[1]
See also
- ↑ 1.0 1.1 1.2 William Ridgeway (1905). The origin and influence of the Thoroughbred horse. University Press. pp. 538. http://books.google.com/books?id=PuETAAAAYAAJ&pg=PA12&dq=ergot. chapter 2
- ↑ Clothier, Jane, The Ergot, p.15, Equine News Autumn 2010
External links
|The above article was imported from Wikipedia.org on 08/24/2010 and may be a modified version of the Original Wikipedia article. See this article's history page for a list of revisions which may have occurred after import. This article is displayed here courtesy of the Wikimedia Foundation, Wikipedia, and its authors/contributors in compliance with the Wikimedia Terms of Use Agreement. This article was imported and is licensed under the terms of the Creative Commons Attribution/Share-Alike License 3.0 (CC-BY-SA). Clicking on photos, videos, or drawings in this article will display copyright and license information for that non-text media where available.


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Fitness Rx of Easton and Danny Russo take Women's Only Program on National Stage
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British And Indian Observer Newspaper Archives
April 18, 1824
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Sunday, April 18, 1824
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Sunday, April 11, 1824
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British And Indian Observer
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British And Indian Observer
London, Middlesex
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British And Indian Observer (Newspaper) - April 18, 1824, London, Middlesex PkfSTllBSSSED -SBmERS at Ike CAPE of OOOD. � HOPE;-TiKCtnBin{ttee'"fortif�irtfinr the ��bMM4p�ioH tbs reticf tBpat� j|f4 ivMrtt vbicb bave bMS paUtthfld. h beofmM ci]|>erflB(MM 10 pot tcith any addiiionM ar. ^tnun^t to excite � CMapa^itoaie craii4eratioQ of their iteplcK cable caae. Their motives for giAOit^theh- nxfhre l&nd it mfflttlH: beced werefunndrtlfd mastfmtances on the 4mperioai�le�iMt duties repeal bill, tbr ainoa dotk^vperi ttlt, (ke paetage i�terbiH,4fa� MHbank pe6i-teatiarybilUthc IrU!#)aard af work* wE^^�� port of the falariet, peaaions, ana rnrtuHtes, j^raated by the East India Conwany.-LaU on tbe tah]f. The �wgms ttlfSBOWWE avaHing tiJiuelf df ihe privi)cfe�Q96f(d by their forAihijrs, iMroSiiciiA a biU, vbieh iud already |Men before fhe haat^ on a arirc^ag year, aad abould more tfaatltte fradalirfttlme: qiM ni^^ii Jts4>l]ject iraa to gire to EagliA CathciKcs'Hbt^ right of votitfg-at �le�i9a# i(rfiH]aadQther biQ toiatrodacr vilbia nAotlf^ii^w enaUe B^glisb Patbalie^ t� hdd-the aaue office* ia%^l^ . TbaMiL'eoJdb^4�f.Whi%W�A^}�� . Sir J. Ne#pltirt�id ftfr.^^tfi^�dW{OVha oaetAKni-iatal^a �riiap* lJ� p��iS�f^*��^- The jietitioli W tbea dieA�fted to M �> t[�b :4Ufl*, aad 'mOvUkfai^local tax^^ w'nM iHSHtiin^ftVii^ orifrr^V6e�anibiIfited.. . ' ; MM (tin. �eWa'.Inman - -I Wro Morjtan, Jun. 1 Candy, losq. . - 5 John BnrniM, E�q. Kil. 4(eiMv - 9 HHt and KirkaatricU � W, B. P. a dotation . 1 Philip OmmhvA^ i MMiri K. a�d J.. K^fchrc- fiwd . ,.2 At the Treasurer'a. Robert Barrlgv, E�q. Samuel Mills, rliiq. Mr. R. B. Klytli Mr, John (Jewi - - I I dj M.P I>�VBr, Wonry, Julnuind, aud Frank - 0 �lr�.PaJmer . . 5 iHon. Uaard MoACtod Patr4ck��atiy, Ea 10 10 0 3 3 0 00 0 0 - 10 10 0 0 . Peter Le Cocq, Esq. 1 0 0 o;A. J. Le Mesuriur, Jun. 0"0 Esq.- - - - J 0 AiiCU:ttas Brovne, Esq. b 0 .i.D.B. - - 10s. 6d. 10 0 Tbe Umn of \> ii>c�.cst�r 1 1 0 0 OAet. Geo. J. M^gendie 100 Subscriptions are received by the Trcasunor, Wm. Fry, Esq. _1 MildredVcourt, Poultry; by Messrs. Frys and Chapman,-suid the several Bankers in the Metropolis j by Mr. Thomas Un-4arnr�)�d, Si, Fleet^ret-t. Aj^nl ti� the Connnitlee at Cape Tovrn. Aod^y theCaoiMitteu ivt the city nf London Tav>ern, where ail communiratious are to i>e addres^d. W. M. HARRIES, Hon. Sec, Oty of I.ondon Tavern, April 15, 1B84.____ TO FAMILIES OR LAIwF.8 GOIN'G TO TUE EAsr IMJIES. a Feraon wbo wishes to join ber Huaband sai ChiUlrea, XjL. hbo are at Madran, it desiroas wf engaging Milba Family readies as SERVANT durinctfo* voyage. has bam to laeili8ihaWy of' imy^jwlSoo hd. ^grifjMiiiiifTe ^tt�riyabsard,and�oi tleaA^that ^ faoaae wooM a*t 1^ (he �#pit n^^t ton conunHtee np�tdra, �bettm iTWB- LjQSmNl^TpN tai4 tUt bought '^e^^asnot^^f^lnr^.ii coonJifeeft, hirt he ^laH Vi||N>aat, ��c eAarsetd be �ai��etL . iSAm^'i^ ikoeikt tii� bill __ - 9^4�tfldVa^4b�af]L�lHMt�iir ^ �ah bath. Suaday, ( keep aa weH observed thj^ rcf ( te their lomeni: aad thef aale tff t��toi^Uie �bh�Ib. aa�i^y Ua aa the tables aad* tioaof pohllctli�.l3, Cully I^^DETS, WRITERS, and MIDSHIPMEN to INDIA, or Piwsciigors generally t� any part of the (Uobe, can Ub J eauipped with ever^ requisite for the voyage and arrival, at one aay'H notice, obtaining White Jean and Satteen Jackets, medium sizes, from 6g. 9d. to lO^i. ; diito WaisUoati, 4s. to (is.; ditto Truwsrrs, 6s. to lUs.; Umti ditto, 6e.; DnII ditto, 6s. 9d. to Hi.I White Moneilles WaistcoaU, 6s. to IQs. . { Black and Blae Coats, 5is. to (i8s.� Uressinx Gowos, IK td i Travelli.ig Cloaks, 38s. to 48s. t when made to order, 101. per cent, extxa ; Cotton i>birts, 3^. to 6s.; a( SILVER and CO.'S (late Arrow smith and SUver), Clotbiers, 9, CorahiU, removed from No. 3. THE jtHMY. DeOMbmentb beloaging to several regiments marched yesterday morning from the recrwiting deuartraent in Wesfininiter, for Windsor, Chichester, Winchester, Partsmoath, aud the Isle of Wight. New Lcviks.-By the retam whtch has been madowning College aud R�ctor nf Rothorhithe, Surrey, was on Friday last admitted UUtetorin Diviniiy. The Rev. (ieane WMtcToord, B.A. Fellow of J�su� College (third aon of J. R. Whitefoord), l�s been insiituted to tho Rcc-u>cy of Wral in ine artiUery, and the rest of tlie above-mentioned population. Glass gave �o lav^ur-aWe an account of the ishind, which only nine rabies in H.ameler, that it may be of importance to vessels, ou their {'�i'uge tu Van Diemau's Laad, to touch there ; tbcy will 'M.- ,ur� of a luoat favourable Feceptioa. There are ot\ Ibe itslaiid great plenty of pi�, goata, potatoes, cabba4;es, ^c. ; abandance of nsh,andexcellefft water. This l^lc colony had at tbe time upwards of SO tons of potatoes to ^siioseof. The island is very fertile, in fact, m every ihin^ dexiiabie to settlers ; and l� priayint fof a dmwhnck on unaofd wool \'tri��nt� af CarUa)eag;i^aat the fraat ot money �>r the bnihling of cburchea ( from ttvo lodWidiiala, wboaff conaiderable brkk-Audters tlu; nei^buaHKlBd of London, "Staying for a' removal of tbe duty on am'ali coala (atraiaed thMWfth a oae-isch ahrre) censing into tha pdrt of Uadoa : >� tlM Pftsbtterf (�a we aMea�Md) ff F�rf�r. North iQiMfi, praying for the total repc�i of the witKluw Ux 1, from the iaMbitanUof Axhridge, In the ^oifuty of Somerset, praying for ibr repeal of rdeivd to *o printed. Tbe boa. gaatleman nl�o prearnteA a petkia� fraaa ihr froemaaooa of AnnMh, ararifig to he pat 9V>� IkP fame foodag wiih t|ie freeniaaoaa in A�gl'�d, - ((rdoned u>j�e wHatrd. , SirM. W..Rhlley gave notice Jtutt on tlie ^�h of M�jr h� Would inoit for leare ta bring in a bill to re'viac and ooaaohdild the atsiap dtitiea. Mr. Hubhoiiae preaeated pet'tiona agahtst tbe n^nmeramllh bill, the St. Catherioe'a dock bill, and the proposed rtiMKat Fleet Market.-Ordered to lie cm tbe table. Mr Haakiaaoa gasv aatice tlist be would, to-aiorro�r. nm* in iM�t JohdMK to a Uii to alUijr tbe botdaia of tetril^^pklk' �mi latMinlwir]). ipanyiiiiil. toeonvtrit tbe saaieMrftMr tSt exportatlaa The tight hon. gent itlso gave ootiee, that be would more for leare to bring in a l>ill to anead the law with respect to principal and factor. Mr.SKCRETARY PEEL moved the order of the day for the third reading of tbe alien Will, which afforded a few meinbera who could not be heard on iu former stages an opportunity of (as Mr. Drnman hooeUly termed it) " wearing out tbe patience of the Houae byrepeating Hnroiiieats wlitcb had been often urged i>�fore." Mr. Lcnnard did more, for he moved aa an amendment, that the bill be read that diiy six inoniUs. None of tbe Ministers thought it necessnry to notice olijectiona twice an-aaered before. Tkey suffered llie House therefore to proceed to H divuioo without a'nv ettort to influence one rote ia favour of, the uieasure, aad yet obtained a nmjorilv of 93 lo 40, and oa the I joamed at balf-pa^t nine o'clock, question that tlie bill do pnss, one of 111 to 47. The Report of Uie Comiiiiitee npou the proposed grant of .500,0001 for building new Churches was then brought np and ajrreed to, although Mr. Hume moved that it be received that lUv rnx months, a motion which was rejected by a maSority of 144 to 30. Ua the nratioR of the CbanceHor of the Exchequer, the House resolved Haelf into a commitute on tlie customs datiea bill.- Report on Ibc 3d of May. On tKe Biotioo of Mr. S. Wortley, the Unuae went inloa com-Hiittee oa the gaote lawa anendnwai biW, aud tlie houae bctag hi cuinniittee, Mr. S. WORTLEY proposed that the slicing of rabbiU should be pnniahable aa well ns tlie'Stealing of gHiue.-Agreed to. On the daitae giving the nmristrntes in petty seskiona the power to convict for a third offence, Mr. MUNDAY thought this power should he given only to tbe judgea of assize or the quarter .-ession*. He propoK-d an amendment accordingly, to give the priaoner the option of being tiied by thoar'courts. Mr. S. WORTLKV agreed to the nmcndmeBt, which was adopted and incorporated with the clause. Ou tbe clause prohibitiog the fixing of snures, excepting by gamekeepers. Colonel DAVIES objected to the clauv, � rose to oppose the clause which prohibited *U pcraoasfrom aeltteg game without iireuse. He observed that renieoa, pouhry, and other articles, were sold without license, aad be did not see whr game should be sold with license. Mr. S. WOI^TLEY ropportrd the clause, which finally agreed to Mr.?. aTtUbUl iILof aum-tit,i|4tta(%baH,tolte rm dp^ke iQ jfiHn)f�r^�f the tepetH [^TQiV tuj)ported the niotcon. IQw Honie tbtn airidol, when thereii{^)earcd- . ' FW�beoK)ti*n, 62-^ dgafaitll, 6 I majority, *6. y .Jl^i lfc^.HK)ved for. ceiwi.h iejoma rdatuig to tbcappra-^ pr^tmi of the jnoncy for boildtng octr churcbea, tit.i^itr :(�catt4ed the mbllod,'whl^ was agreed to. llr.whwmored also for a reiorn ahewiug theananbero^ . ehp 4�d4v|iap�ls of tbtbChnrch of Ea^laad ia eaeh pftri^ ^ jlf^l^tf^ mpd Watr^; and4^i>otber return, Shewlag tbe number di Tbe house then diii,le.l-Ktw theaAeaditKat. S4, agalall it, #^&aaa jrrahff^to dissenters in the last year.-^^erc*. to bring'ia | btttloiiUoe. Roman CMhoiies in fiiwy^ apeo tbe same fovtiag >* {jiiakeia,, Jews, and Roman Catho)^ ia li-rlantl, witlr'n's^'t to marriM-es. llic b>^ose hTtenrfeiliikltfttt lotvi a comcnittee op tb� vafe4�Bi�r�g act, wht'tt Mr. Hu�hiaaaa �tq)laiBed U�r lartlMiea of btS' phw far �)h>wiag - hdnded cots to be tqmed intoilour (qir rxportatioQi An^* pers^ro tvbo paspeaaca foreign wheat in bond is to be at liberty, upon giring f^P*f aecw^y.'totakttoacaiiy'quaatTty of wheat and convert U iifto flour. 'Fbe American barrel, contniifing 196 pounds of flour, isobtaitied tcpm five busjmia oS yqod wiicat. But is tbia coi^ ia now de Cbancellor 0/ tjie Kxcbequer moved the or.ler of the day for tiie second reatKdg of (be eer duties bin,-wliKfa was disposed of ia the^oteiaanaer, an was the aogar bouaties ^11. "^jM CbaoceVlor of the. Rxjchequer moved the aecond reading of the ExchcqneV bill dnpilblic works bill^Read a second time, aad oTdelvd lo be conMHUIed toMMorroir. . Mt. C, Vntot Bi�.rt^ houae ivt^ *^ ooaimiUea upon the Ashery acts. The right ^nourable geownan sohiaitted certain iwioliitiohs relatTvB to tiife* repeal of ^'boaativa. Tha bonntv tfrat not tn be taken HH�y to aadde&iy as was first propoaed, hot was lo bo gradaiUL}- cediujtd.-He moved lha rcMluiioBa acrord-lugly. AatT a few words from Mr. D. Gilbert aad Mr. Bright, the xeaohiiions were agreed ta. The house resumed, and the report wu ordered to be reoesrad il^laorraw. The retxvT on glass Antlea vNa broog^t op anal agreed to, and a bill nrB.y ordered to be brooglit ia foun^ upon the re|>ort. The saving hanks hills wits postponed to the 4th of May. Tbe Scotch juries bill was recominittrd on tlie motion of Mr. Kennedy, and the bill was immediately carried through a committee.-Report lo-wjorrow. On the imition of Dr. Lu>hlngton, the mairiage Rct amendment bill was read a second time, and committed for to-morrow. Tlie vagrant laws amendment bill went throagh a committee. -Report to lie considered on tbe 6th of May. The new street bill was read a �ecund time, and committed for tbe 5th of May. Tbe insolvent dd)tArB' InU was read a third time and passed. The other orders nf the tiny being disposed of, the bouse ad- Ut, fiUM�^edled4he attentioo�f'thefaouie to the alale. �'* UUitra, in the articleahHl :hnd been lowered incon-'eqiieiW^ cf the opening of the trade. What he now twrnplaiufd-^ atf vasi tbat v^nmrnt tbe East India t^uhpany badM^eed .important fort at Snmatra to tbe Dutch, wkboaL aiakt^g is dueplsivision for individuals who luid there expended their Capital-iu the growth of those articlea, in thetleiief tbiit they wvttht ifc ^ncou^BgBd and proiecled. He complained also of a hreachof faith with lUe natives The Governor, Sir Stamford Raih:�, liaddet hired tbat the place was held ^mly for the natives, aad fothcmV tberef.jre, alone it oogbt to be restored. This Otiyht to be oarticularlr aticodcd lo, seeiog the cuaduct which �had been displayed by the Dutch at Java. He moved foreertaiii. returns of tho quaiititlcs of mace, cfoves, aad-nntmega imported by the East India Company aad others, in the laatQB years. 14c WYAi N aaid he woyld nut oppose the jh^tion, though he o aiov�d for a copy of the (iratiea entered into bctwcQB tbe East India Company and tbe Chiefs of Suioatra. Ordered Mr. HDSKk;80N moved for leave to brii^ i� a bill to iJwr abd aoMBrtd th� Uw� relating to factosv and tbeir princi-tala. He w;;uld ia a future stage open the details of the 'sub-ect, wh.ibfa was oae of great importance In our eommercial law. -LeaW glvni. SirOEORGE^HILL OBoved for, and obtained leave to briog in a bill to regulate tbe nnmber of paaaengera conveyed in steam beata between Great Btiuhi and Ireland. Mf. KSNNKUYmo^od the bringing op tif the Report on the Seotch Joriea bill. Mr. LUSHINGTON subniitted to the hon. Member, that, h> the presentaUte of the house, it woold not be of any advaflMMrbiaits piett Ua atotloo. He the�eiore begged hhono^h�d^��>dati>�r� verewvwidmattefa of poUie boai-neaa bdbre tbe boaaeunopposed, wbkh U would be deairable to get throajFh. Mr. KEMHE0T said he had no wish to oppose pubfic business, hot be did not tbiuk that. 00 this occasion, be was tbe person that ought lobe called upon to give way. The ri|ibt hon. gentleman would perhaps apply to hia learned friend, the learned lord wbo opposed the motion. Strangers were then ordered to withdraw ; tbe house divided ; hut there bring only twelve members proaeat, the house j necessarily adjourned. BMdh felatWato the redeaap-^ (te paMhsddbt, aad sm� move (kat^heUte ftttt 3d ^ ftw^, >pa. tti hooae a^oumed^ Lli�Iy-toa(QMura,ame wMM^aot aoireiL-Tbe irtttaa r,teh�iiHt tt^tin^ htaled ia anawer to Mr. eiBce, tharthe Muclionof daty on rum waate eoaunaaM npaa Ib'e tossing of the net-Tfik report mu ordereft lia be taken idio conaideratkm the 3d of Miqry the masters arising out of these coinbinatious, and in the riik which t^ey might incur for thi- future, there were obrmns reasons why tliey wished tbe laws to be conttaaed, and why they now abstaiued from coming forward to give evidence. Mr. MA.VSFIELD said, tbat he was sorry lo heartrbtft hae affected by this bill; 10,00U were mentioned, but in fact there were but 4,400 in Of parish. The number of bouses too weie mentioned at 1400, but there were not more than 800. This was an exaggeration caused hy rival dock companies Tbe other obji-cfion, as to the Want of aotiees, was of no weight, as tbe bouses iu que>tion would be rcsdered more ralnahle iiy the alteration proposed--ITie motion was agreed to. Mr. HUME presented a petition from Bermondsey, and ueighliouring places againat the St. Catlierine'a dock bill.-Referred to the eommittee 00 the bill. Dr. LUSHING rO.N brought in a bill for altering the duties on hides and skins. Read a fir.st time, and ordered to he read a second lime on Monday tbe 3d of May, after a few words from Mr. Maberly. Petitions against negro slavery were presented from Macclesfield, from Bniiibridge, from Lancaster, and o-'dered to lie on tbe lab^e and W (irinted. Sir GEORGE BILL brought in a bill-for regulating the nauiber of pnsseocer' in steam boats between Great Brit;^in and Ircland.-Read a mat time, and ordered for a second reading on tbe 4tb of May. Sir Geoi^e ilUl alfo bmtuht in a bill for draining the bogs in IrelaaJ, which was disposed of in a manner similai to the last. Mr. DawjKm brought ap from the Home Office several official papers relating (o the aae of the tread miU.-Ordered to be printed. Colonel King presented a petition from Cloyne against the tithe commutation bill.-Ordered to be printed. Mr. P. MOORE presented a petition from Coventry against tbe combination laws. He complained of tbe co^dua of several employers as being peculiarly oppressive. Tue petition was referred to the committee on artisans j as waa a similar petition prcaeolcd by Mr. Moore from Saddle-worth. Mr. Stanley presented a petition from Bolton against the duty on excise licenses, -Ordered to lie on tbe table. Sir THOMAS BARI'NG gave notice, that soon after the holidays be sboul^l introduce to the attention of the bouse the claims of Mr. M'Adam ia respect of his exertions to improve tbe public roads. Dr. PHJLLIMOilE brought in a bill to l^alize catholic marria^res.-Read a first time, and ordered for a second reading on the 3d of May. Lord A. HAMILTON moved for severail returns relative to the amount of tbe fee fund oi the court of session in Scotland. -Ortlered. Mr. S. RICE presented a petition from tbe Roman ratboKcs of i>rogbeda, nnmeronsfy rigned, complaining of the practice which prevaUed in tbat part of the eonntry of excluding catholics from �erving 00 grand juries and other pablic offices, although tbeir property and numbers compared with those of protestunts was-in pie proportion of nine to one; and attbongh tbey were rendered eligible for the officer ia question by an act passed ia tlie year 1793. 'fhey prayed for a revision of the whole of the laws relating to catholica.-The petition waa ordered to lie on the tabhi. Mr. Coortenay brooght up therepwt on tbe county gatda bill. Read-and ordered for.consideration owtbe 3d of May. Mr. Hume broiigbt up a report of the cominitlae of artizana.- Ordered to be printed. Mr. Hu^moved fqr aeveral returns YitatiMtbi^diatiOeries. .-Ordered.. � . Sir T. Lethbf^idge presented a petition ftom W^tahire agaiast the repeal of the wool duty.-Ordered to be printed. Mr. Butteirworth presented a petition from Doncaater against cruelty to animalr; aud another firom several poulterers and Sierra LeoaeGazattea to the 31st of Jeonary inclnsive hava been received. Their accounts of the growing trade of the cahioy are highly gratifying. The present sUte of Sierra Leone, wbik it fonns a striking contrast with tbe ill-futed. thongh 5enevolfat attempt which waa made in 1792, to colonise the island of Bu-laina, illustrates in a striking manner the soundness of some of the views entertained by captnin Beaver, wbo corninaoded thAt expedition.-*' Aa one of the means that would inevitably tend lo the abolition of the slave trade," says he, " 1 would recommend the cultivation of Ati^ bv its free aatlvet. I know ibat those who choose always to see the African character in its worst light, will probably say the aativca will never be hsHuoed vokia-tarily to labour. As far aa iny knowledge of the AfricMM witt enable me to judge, I bavi ho doubt nf tbeir resdilf MBIliif the earth for lui�, vhtatitt �aaacMit^fy4Ma^ emptoy them, f navar saw anea work harder,.piora frfM^^IV^ more regularly, generally speaking, than those /ree natlvea whom I employed upon the Istaod Of BulHiiia. Now what e0ktt would tbe culbradoa of Africa bav> upon its intiabttanta } Aa cultivation of the soil muat neeeasarily indut e commerce : and the intercourse resulting from this exchange, this liartcr, tbia trade, vrill and must soften and civilise Hie more barbarous of the two parties carrying it on; and will by deyrees introdoce letters, and in tbe end the Christian reli^iua. Civilisation aiay for some time be confined to the territorv colonised ; but commerce will begin immediately to elt.-nd by little and little mio the interior. The convenience of a mart being unre establiahad, and the certainty af European articles being always lo be found there, would induce the mterior traders to coiue, instead of annually, whenever they bad commodities to sell, which wooM keep up, except in the rains, a roostHot communication with tbe interior. This consUnt communication would tend to civilisa all those people through whose territories it was carried on ; and this increased civihaation woold produce additional security, which would tcad alao to augmeut that communication."-Thcsa , predictions, publiahed nineteen years ago, nre now every one of them literally accompliabed at Sierra Leone ; nnd, what is most remarkable, by the agency (excluding miliUiyj of titUe ntoM than a hundred resident white persons ! The following are extracts from these papers : - " Freetown, Satunlay, Jan. 31,1824. " Among tbe naaoy subjectj of coagraiutatitMi We linve t� offer to those wbo feel interested in the daily i;icreH8ing prosperity of this riaing aettlement, we may notice tlie arrival of a large ship for a cargo of timber from the port of DnbAn. '/liia is another convincing proof tbat the value of tUis Hrticlo is bc-couii g more generally known. Since our last statement, two large ships for cargoes of the same kind have arrived, and more are daily expected. The only fear expressed by the trucfers is, that they shall not be able to load them fast waougli. We have long ogosii�ted onr canviction that the imuieu.se reioiircus of tbia colony were notsitfltnently known, uad every hour provesCbe truth of oiir odaertioo. " We have much p'eafipw'in drawing the altenlian of onr readers lo an advertisement, at the end of our (lapi-r, relative td esUbiiahiug a prayer-book society in the colony, and sincerely hope thai this suggestion will be readily met hy tbe wcH-wisbera of the CO oui.Hts. Am ng those wbo have observed the want of this inestiiiiahle work 10 the rillage chilrches certain support may be expected ; and from the enlightened liberrtlity that has hitherto been witnessed for the promotion ofChrisliau morality, we have no doubt of its sueeess. " By tbe brig Frances Ann, from Leeward, which fell in wit* his Majesty's brig Swinger at sea, we learn tbat Belzoni had landed in tbe Bight of Benin, where be experienced a slight attack of fever; but^eling himself pertectly recovered in a few days, be started upon his enterprise with every hope of ultiaMte success. If we were inclined to indulge in the gift of prophecy, we should speak very tavourably of his undertaking. This enterprising traveller ceitaioly pos:aad when bia master said " Well, Dick, how are you to .d^ }"~ ** A great deal biilifer, thank you, master," was tbe reply, to tbe astonishment of Mr. Hoarej wbo actually staggered at the pilra-cle. The poor man, we uaderetaod, continues in good health. ;
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Data demonstrate that there are distinct differences between the human mineralocorticoid receptor (MR) and the zebrafish MR despite considerable sequence and functional conservation.
The new frameshift mutation decreased the expression of MR, but not NR3C2 mRNA, and led to decreased MR function, with no dominant negative effect.
dysregulation of GR, MR, FKBP5 (show FKBP5 ELISA Kits), and PTGES3 (show PTGES3 ELISA Kits) in autistic spectrum disorder (ASD (show ARSD ELISA Kits)) and suggest a possible role of inflammation in altered GR function in ASD (show ARSD ELISA Kits).
hyperactive hypothalamo-pituitary-adrenocortical axis in overweight diabetic subjects may be associated with downregulation of 11beta-HSD1 (show HSD11B1 ELISA Kits), MR, and GR in the brain.
Our current findings demonstrate that Arctigenin is an antagonist of MR and effectively decreases the Na/K-ATPase 1 (show ATP1A1 ELISA Kits) gene expression. Our work provides a hint for the drug discovery against cardiovascular disease
Data show that both mineralcorticoid receptor (MR) and G-protein estrogen receptor (show ESR1 ELISA Kits) (GPER (show GPER ELISA Kits)) contribute to the proliferation and migration of breast and endothelial cancer cells by sodium-hydrogen exchanger 1 (show SLC9A1 ELISA Kits) protein (NHE-1 (show SLC9A1 ELISA Kits)) upon aldosterone exposure.
Data show that aldosterone via the mineralocorticoid receptor (MR) reduces microRNA miR (show MLXIP ELISA Kits)-29b in vivo in murine aorta and in human primary and cultured vascular smooth muscle cells (VSMCs).
NR3C2 was found to be significantly associated with longitudinal systolic Blood Pressure change in a Han Chinese population.
Findings indicate that CS-3150 is a selective and highly potent mineralocorticoid receptor antagonist with long-lasting oral activity.
Among the class II HDACs, HDAC4 (show HDAC4 ELISA Kits) interacted with both MR and HDAC3 (show HDAC3 ELISA Kits) after aldosterone stimulation. The nuclear translocation of HDAC4 (show HDAC4 ELISA Kits) was mediated by protein kinase A (PKA) and protein phosphatases (PP)
CBP (show CREBBP ELISA Kits) and p300 (show EP300 ELISA Kits) as lysine acetyltransferases responsible for the regulation of MR
Nr3c2 has a role in mouse skin development in a process that involves HSD11B1 (show HSD11B1 ELISA Kits)/HSD11B2 (show HSD11B2 ELISA Kits)
Inducible Knock-Down of the Mineralocorticoid Receptor in Mice Disturbs Regulation of the Renin (show REN ELISA Kits)-Angiotensin-Aldosterone System and Attenuates Heart Failure Induced by Pressure Overload
Data indicate that endothelial cell mineralocorticoid receptor (MR) deficiency prevented Western diet (WD)-induced diastolic dysfunction, profibrotic, and progrowth signaling.
Cardiomyocyte mineralocorticoid receptor activation impairs acute cardiac functional recovery after ischemic insult.
a cooperative role of MR and cav-1 (show CAV1 ELISA Kits) in regulating vascular contraction and NO-cGMP-mediated relaxation during low NO-high AngII-dependent cardiovascular injury
Upregulation of MR in mouse adipocytes led to increased weight and fat mass, insulin (show INS ELISA Kits) resistance, and metabolic syndrome features without affecting blood pressure.
Data showed that the mRNA expression of glucocorticoid and mineralocorticoid receptors were significantly decreased in splenic macrophages by repeated social defeat. Epigenetic regulation, may play a role in the RSD-induced GC resistance.
Compared to sham-mice, the expression levels of hypothalamic MR, serum glucocorticoid-induced kinase 1 (a marker of MR activity) and AT1R (show AGTRAP ELISA Kits) increased in pressure-overload-mice.
Data indicate that overexpression of constitutively active Rac1 activated mineralocorticoid receptor (MR).
AT1 (show SLC33A1 ELISA Kits)-independent MR activation in the LV might be responsible for the pathogenesis of diabetic cardiomyopathy.
Effects of age, weaning and/or social isolation on the expression of genes regulating mineralocorticoid receptor.
analysis of the interdomain interaction in the mineralocorticoid receptor
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants.
mineralocorticoid receptor
, nuclear receptor subfamily 3, group C, member 2
, nuclear receptor subfamily 3 group C member 2
, aldosterone receptor
, mineralocorticoid receptor 1
, mineralocorticoid receptor delta
, Mineralocorticoid receptor (aldosterone receptor)


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This book is far more than just another tutorial or reference guide - it's a tour through the world of analog design, combining theory and applications with the philosophies behind the design process. Readers will learn how leading analog circuit designers approach problems and how they think about solutions to those problems. They'll also learn about the `analog way' - a broad, flexible method of thinking about analog design tasks.
© 2016, O'Reilly Media, Inc.
(707) 827-7019(800) 889-8969
All trademarks and registered trademarks appearing on oreilly.com are the property of their respective owners.


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Cadillac Forums | Help Us Help You | Advertise | Cadillac Parts |
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I'm testing the waters to see if there's interest in my 4 Michelin X-Ice tires. I can sell these tires and wheels because I now have 4 season tires on my CTS Sport Wagon.
These are 245 x 45/19 size and come complete with TPMS sensors, lugs, locks and the Tire Rack tire covers. The X-Ice tires really transformed my car into a capable winter vehicle. They have only 2500 miles and 9/32'' tread over 2 winters (10/32'' new).


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This 'Engagement' could make a return very soon
Q.Will "Rules of Engagement" be back on the air?
- Judy Picard,
Austin, Colo.
A. Never count the CBS sitcom out for good - not yet, anyway. The show starring David Spade has had an interesting season, to put it mildly.
Originally earmarked for Saturdays, where few series have been placed with first-run episodes unless they're doing less than great on their original nights, "Rules" was redirected to Thursdays when "How to Be a Gentleman" went down fast last fall.
Then the network benched it in favor of Rob Schneider's show, "Rob." At the time of this writing, "Rules" was set to reclaim that slot before the television season ends.
Q.I'm wondering if we'll ever see "Harry's Law" again. They keep changing the time slots.
- Marian Brandel,
Hartsburg, Mo.
A. They certainly do. Originally a Monday night offering, the show was moved to Wednesdays by NBC for the start of this season.
Now, with the network trying to establish a comedy block on that night, the Kathy Bates law drama has just resumed on Sundays.
Admittedly, that much moving around raises questions about the show's long-term prospects, but it continues to have a strong ace to play in Bates, who earned an Emmy nomination for the series for its first round.
Q.I was watching the classic Alfred Hitchcock film "The Birds." Was the little girl who acted with Tippi Hedren and Rod Taylor the same actress who played, as a grown-up, the secretary Robert De Niro assaulted in the remake of "Cape Fear." If no, who is she, and can you tell me a little about her?
- Patty Moore,
Jeffersonville, Ohio
A. There's a certain resemblance, but, no.
The child in "The Birds" was Veronica Cartwright, and the "Cape Fear" actress was Illeana Douglas.
And since we're not exactly sure which "her" you wanted us to tell a little about, here's a little on each of them.
Cartwright - the older sister of Angela Cartwright of "Make Room for Daddy," "Lost in Space" and "The Sound of Music" fame - worked frequently as a youngster, also in other movies including "The Children's Hour" and in such series as "The Twilight Zone" and "Leave It to Beaver."
She also played the title character's daughter early in the run of the show "Daniel Boone," and she has continued as an adult actress in films including "Alien" and the remake of "Invasion of the Body Snatchers" and such other television ventures as "The X-Files" and "Six Feet Under."
Douglas' grandfather was the veteran actor Melvyn Douglas, and she was involved personally and professionally with director Martin Scorsese for a number of years, a likely factor in her being cast in his "Cape Fear."
She also worked for him in "GoodFellas," and they both appear in the Robert Redford-directed "Quiz Show," but not in the same scenes.
She might be best known for her much-acclaimed performance as the singer-songwriter at the heart of the 1996 movie "Grace of My Heart."
Email questions to firstname.lastname@example.com; please include your name, city and state. Personal replies cannot be sent.


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The Quake
"Is she okay?"
"What's wrong with her?"
"Has somebody called an ambulance?"
"She's waking up!"
The crowd that had gathered around her limp body breathed a sigh of relief as a girl with light brown hair wearing jeans and a brown sweater slowly opened her eyes. She stared at the ceiling for a moment, apparently confused. The industrial fluorescent lights seemed to throb in her vision. Her ears were ringing. Then she frowned as she scanned the circle of concerned faces surrounding her.
Embarrassed, she sat up with a start, blood rushing to colour her pale cheeks.
"Are you okay?" Someone asked.
The girl on the floor nodded slowly, though she felt a bit lightheaded. Someone offered a hand to help her to her feet.
"I'm fine." She swayed a little, then caught her balance. Her voice sounded faint. She cleared her throat. "Really."
Some people hesitated, unconvinced, but eventually the group dispersed. Relieved, Katherine leaned against the cool brick wall, watching the students bustle past. They seemed to move too fast, like someone had hit fast forward. She couldn't explain it, but it felt like the whole planet was spinning out of control. Katherine thought she might be sick. She closed her eyes, willing herself not to vomit in the middle of the hallway. She had already embarrassed herself enough for one day.
With her eyes closed, the spinning stopped. The sounds of lockers slamming and shouting students faded into the background, until she couldn't hear them at all.
A boy who wasn't watching where he was going bumped into her and apologized, but Katherine's eyes remained closed - she showed no sign that she had noticed.
She recognized the unconscious, dream-like feeling. It brought back the dream she had been having when she'd fainted - the one with the phone in the office. It was strange, even for a dream, to be able to see perfect detail in a room that she had never seen before in her life. Suddenly the floor started to shudder beneath her.
She was underground. It was so hot, it felt like her skin was melting. Katherine screamed. The walls were shaking too. She didn't know where she was, but she knew she would be crushed.
When she opened her eyes she was back in school. Apparently the quake part of her dream had been noticed by everyone. Though it was over now, everyone watched the walls and floor nervously. A couple boys laughed and high-fived one another.
Katherine felt perfectly fine now. Without making eye contact with anyone, she quietly found her locker and collected her books.
She walked home quickly without stopping to look back.


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Morgan Stanley: sell GBP/USD at 1.6360
Morgan Stanley strategists await a rebound in GBP/USD to reestablish short positions. In their view, Scottish referendum fears will pull the pair down this week after a corrective recovery.
Trade signal: Sell LIMIT at 1.6360, Take Profit 1.5860, Stop Loss 1.6460
Chart. Daily GBP/USD


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Home >> Cupboard Cabinet Door Hardware 134mm Long Metal Pull Handle Bronze Tone 2pcs w Screws
- The Pull Handle is widely used for all kinds of furniture hardware, such as door, cabinet, drawer, cupboard, etc.
- Dress up your furniture with this new pull handle.
- Screws are included here.
|Package Content
|2 x Pull Handle, 4 x Screws
|Product Name
|Pull Handle
|Main Color
|Bronze Tone
|Mount Hole Center Distance
|Overall Size
|134 x 14 x 20mm/5.3" x 0.55" x 0.8"(L*W*H)
|Thread Hole Dia
|Screws Size
|3.7 x 22mm/0.15" x 0.87"(ThreadD*L)
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Help to Empower our Teens - volunteer to teach in Summer Camp
Cause Areas
WhenSat Jun 17, 2017 09:15 AM - Sat Jul 22, 2017 03:15 PM
Where1679 Columbia DriveDecatur, GA 30032
iYEP (Youth Empowerment Program) is an annual summer training in leadership, lif skills, and entrepreneurship for teens and young adults aged 13 to 26. The youth this year are middle and high school teens.
This is a one day a week camp, and volunteers are needed to help implement the training of the youth, on Saturdays only between 10 AM and 3 PM, from June 17 - July 22, 2017.
Tutors will be required to attend orientation on June 10 to be introduced to the curriculum and house rules. If you have strengths in marketing, finance, accounting, business plan, life skills, STEM, e-commerce, social media, fitness, health and nutrition, evaluation, you will be an asset to the program.
Our program thrives when we have people like you volunteering your expertise and time to empower the next generation!
Please contact the Program Director at firstname.lastname@example.com.
- Marketing Strategy & Planning
- Youth Activities Management
- Brand Development & Messaging
- Teaching / Instruction
- E-commerce
- Bookkeeping
Good Match For
Requirements & Commitment
- Orientation or Training
- Weekly 2-hour planning meetings starting May 1
- Integrity, Punctuality, Commitment, love for youth


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This cute, short ad was featured in the 'Pitch' section of the TV show "The Gruen Transfer.â€
The TV show gives two competing agencies strange briefs with approximately $500 spending money to create a 60-second ad.
Created by Stuart Vidler, Cubes R Us won the "How to sell Ice to the Eskimos†brief, which ended up as one of the winning ads.
Implications - Companies recognize that they need to challenge their advertising agencies to create a unique marketing campaign to grab the attention of their viewers. Ads such as Cubes R Us show how possible it is for clever copy and art direction to outweigh a big budget. Ad agencies are now worried because of the consumer move to social media. This shift calls for better commercials that will generate stir amongst viewers so it can reach viral status.
$500 TV Ads
More Stats +/-
Halloween YouTube Contest
Student Ad Contests
Colorfully Revitalized Mid-Tops
Southern Dessert-Flavored Cookies
Simplified Modern Speaker Systems
Cubes R Us Featured on "The Gruen Transfer"
Jun 5, 2009 Updated: May 19 2011By: Tisah Tucknott -
References: cubesrus.au & digitalbuzzblog
References: cubesrus.au & digitalbuzzblog


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The number of e- services provided on the portal e-government by public agencies is increasing rapidly.
Thus, the number of e-services provided through the portal has reached 410.
At present, 322 e-services out of a total of 452, approved by the Cabinet of Ministers, are available on the portal.
In general, the number of e-services available on the websites of government agencies is 481.


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Chateau de Sanse
No prices found through our partners. Please contact the business directly or check some of our recommended alternatives.
How has this hotel rated in the past?
- Meeting rooms/conference facilities
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- Swimming pool
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Photos of Chateau de Sanse
Travelers also recommend:
- Restaurant
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- Breakfast Available
- Non-smoking rooms
- Free High-Speed Internet
- Wheelchair accessibility
- Free parking
- Family rooms
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- All-Suites Property
- Meeting rooms/conference facilities
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- Babysitting service
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TripAdvisor Reviews Chateau de Sanse Ste Radegonde
Travel Blogs from Ste Radegonde
Day Five
What a wonderful morning. We were able to sleep in until 7:45 AM to report to breakfast at 8:15 AM! It was so nice! We had another French breakfast that consists of croissants, cereal, ham, and cheese. Then we boarded the coach for a day at Disneyland Paris. Everyone enjoyed the day! We went to Earl of Sandwich for lunch. We had a choice of ...
Paris Disney
... knows how to entertain you and keep you in a line for an attraction for hours. Disney Dreams is a show they project image off the castle using lasers and water jets and its fantastic. We're going to attempt to see it again tonight, only if we manage to pack our bags in time ;) Our excess baggage crisis was adverted after purchasing two prepaid shipping boxes from the local post office. We did have ...
Disneyland Paris
... Greg and I got more lost in the Alice in Wonderland maze, as the kids raced off before us.
Highlights for me was watching the boys nerves at the start of a ride, change to extreme excitement and hell yeahs after.
Watching my little girl's face change to pure joy as she saw her movie idols Elsa and Anna in the flesh, as Let it Go was playing across the park.
The finale was ...
This morning our first stop was Sacre Coeur Basilica and Mont Martre. The basilica was beautiful! We were able to do some shopping and I even got to try a crepe. My crepe had Nutella and banana in it. Our next activity was a 2 hour bus tour around Paris. We stopped at the opera house, the Arch de Triumph the ...
Midnight in Paris (uploading this at 12:00)
... not exaggerating) we spent some time enjoying the architecture and atmosphere of the plaza. Dinner went smoothly, and with full bellies we settled in for an hourlong cruise of La Seine. The nighttime glimpse into Paris only adds to my praise of the beauty here. Again, I went briefly because it's been a long day, I need some sleep, and we'll be waking up at 3:30 tomorrow morning to catch a train to Milan. Four hours left until it's, "Au Revoir Paris!" (:/) But it's, "Bongiorno ...


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Long LostMature
What else is there to do at night but visit the taverns and brothels? Nothing really. So that's where I found myself when I heard an announcement that caught my attention.
"Join Admiral Dragos and his crew on a daring mission to rescue the beautiful daughter of the Pirate Lord of Flame!"
Dragos? There was only one Dragos family that I had ever heard of. I would know better than most. I got up from my table and went to the herald trumpeting the news.
"Excuse me. Admiral Dragos... does he have a first name?"
"Why yes he does! Dravet or Dravel or..."
"Ah yes! Draven Dragos! That's it! Do you know him? Would you like to join his crew?"
"Well I'm not sure I want to join him just yet, but I do know him. Do you know where I might him?
"Yes. He is at the White Lantern Inn for the moment. Ah before you go... might I take your name down as un-decided for now?"
"Krux. Krux Dragos."
The herald looked up at me for a moment. his eyes searching my face, my body, looking for similarities. He must have found some sort of resemblance because his mouth dropped open and his eyes widened.
"Y-You are the Admiral's... brother sir?"
"Last I checked I was... it has been a while since the "admiral" and I talked... we were sep-... Why am I telling you this? Thank you for your help. I best be off."
I left the herald and the inn behind and set out in search of my brother. We hadn't parted under the best of circumstances. Not that we had argued... it was a bit more complicated than that. He uh... he was captured... by the Pirate Lord of Frost. It had been nearly 12 years.
After a few wrong turns, a few conversations with strangers, and a few bribes, I finally made my way to the White Lantern. I pushed the door open and was hit with the smells and sounds of a bar. And a tavern brawl. I stayed against the wall and looked around the room. In the midst of the chaos I saw someone who looked remarkably like me.
It was Draven, and he was in the middle of the fight.
I dove into the melee and grabbed him, attempting to pull him out. He must have thought I was an enemy brawler and he slugged me on the nose. Draven didn't recognize me, but he looked drunk so it didn't surprise me.
I punched him back and with a shout he went for his swords, a cutlass and a scimitar. I drew my own weapons, a longsword and shortsword and with a clash we met. He went for a slash across my chest, but I blocked and slipped under his next blow. I pulled his feet out from under him and and gave him a return slash. He rolled and rose with a roar shoving me back and pulling a out a flintlock pistol.
We stood facing each other, neither moving or speaking.
He stared at me, his mind searching my face, trying to push through the influence of the alcohol and figure out who I was.
"D-Do I know you?"
"I believe you do Admiral."
"You aren't... K-Krux?"
"Yes I am. It's been a long time brother..." I noticed the tatoos around his eye, and upon a closer look I realized that they weren't tatoos but curse markers.
"Brother what trouble have you gotten yourself into now?"


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5330 S Silverstone Drive NE, Comstock Park MI, 49321
Sold Price:
5 beds , 3 Full baths
1,921 sqft
Status: Closed
Last Updated: 5/27/2017 2:17 AM
Description for 5330 S Silverstone Drive NE Comstock Park, MI 49321
The fussiest home buyers will love this meticulously maintained Daylight Ranch with over 1900 Sq Ft on the main floor. There are 5+ Bedrooms, 3 Baths, and over 2800 square feet of finished living area. It has been professionally landscaped and has underground sprinkling, a sod-like lawn, a deck, and a patio. There is very beautiful woodwork throughout, a big super-sharp kitchen, a Formal Dining Room, a Master Suite with a whirlpool tub, Cathedral Ceilings, Tray Ceilings, Central Air a fireplace, a four season sun room, a big family room downstairs, and a huge dream workshop. There is an office/library, plus two legal bedrooms, and tons of storage in the basement. Check out all the photos! This is an awesome home! Come take a look! Please, No showings before Monday, May 25th.
Sold Price:
Sold Date:06/26/2015
Plainfield Twp
3 Full
1,921 (approx)
Listing Information
Plainfield Twp
Public Sewer
Cable TV, Natural Gas
School Information
Room Information
Living Room
Butler Pantry
Interior Features
Central Vacuum, Humidifier, Dishwasher, Dryer, Garbage Disposal, Microwave, Convection Oven, Range, Refrigerator, Washer
Central Air, Ceiling Fan(s)
Gas Heat, Forced Air
Basement, Daylight
1, Gas logs
Exterior / Lot Features
Attached Garage, 2 Car Garage
Deck, Patio
In Ground Sprinklers
134 x 150 x 60 x 187
Sidewalks, Paved Road, Public Roads
Driving Directions
East off Pine Island Dr. just North of 6 Mile on Pendleton to Silverstone, South to the home.
Financial Considerations
Listing Price History
Comstock Park Real Estate
Comstock Park is located in Michigan. Comstock Park, Michigan 49321 has a population of 10,407.
The median household income in Comstock Park, Michigan 49321 is $40,451. The median household income for the surrounding county is $52,716 compared to the national median of $53,482. The median age of people living in Comstock Park 49321 is 30.9 years.
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A Rowebotic Style Of Living
We packed up our Canadian home on the East Coast and headed south to Costa Rica. After eloping in Guanacaste province we fell in love with the country and keep coming back each year. This time we are staying for 6+plus months in hopes of taking our family around the world. This blog is all about how we are making a living by living our own lives our own way. We are breaking free of "robotic living": going to work every day and leaving our family/home behind. We are turning to "Rowebotic living": living our lives and raising our kids in a world and way we are excited about. Lot's of quality time and lot's of quality stories!
We want to help you make this dream come true for your family! Check out our site and send and any questions! If you want this type of lifestyle, we can help you achieve it!


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|Vemund Østgaard (JIRA) <j...@apache.org>
|[jira] Updated: (DERBY-3445) Make it easier to use the EMMA tool to measure the code coverage of the Derby testing
|Mon, 25 Feb 2008 16:50:53 GMT
[ https://issues.apache.org/jira/browse/DERBY-3445?page=com.atlassian.jira.plugin.system.issuetabpanels:all-tabpanel ] Vemund Østgaard updated DERBY-3445: ----------------------------------- Attachment: 3445-testspecific-diff 3445-general-diff I've made a patch that I think makes it a lot easier to run codecoverage measurements with the junit suites using EMMA and ant 1.7. Just download emma.jar and emma_ant.jar and place them under tools/java/ and everything should work, at least with ant 1.7. I have put the general changes in a patchfile named 3445-general-diff. The changes in this patch are: - A lot of new permissions in derby_tests.policy, both for EMMA writing to its coverage.ec file, and for running junit from ant with ant version 1.7 which writes to some temporary files. - SecurityManagerSetup now sets a new property "derbyTesting.emma" to the location of emma.jar. This is used in the policy files to grant permissions to emma.jar, without having to know where it will be placed by the person running the test. - Several new tasks are added to build.xml for running tests with EMMA. The most important one is emma-report, which instruments your jar-files and places the instrumented copies under jars/emma/, and then runs the junit task <junit-all> before it creates three sets of coverage reports (txt, xml and html) linked to the derby source files. I've adapted the old <junit-all> task to work with EMMA and ant 1.7. - Added properties for emma.jar and emma_ant.jar in tools/ant/extrapath.properties. If you I have made some test-specific changes as well, and put them in a separate pathfile named 3445-testspecific-diff. These changes are: - Extra permissions in SecurityPolicyReloadingTest.initial.policy, NetworkServerControlApiTest.policy and ServerPropertiesTest.policy to get these tests to run with EMMA and ant 1.7. - Added emma.jar to classpath for classloader used in SysinfoLocaleTest.java. - Added property emma.verbosity.level=silent to commandline used in SecureServerTest.java. This is a first step to make it easier to run with EMMA. Going forward, it might be useful to improve the emma-tasks in build.xml to be able to run codecoverage experiments with the classes in addition to the jars and to integrate with the other junit-tasks as well. > Make it easier to use the EMMA tool to measure the code coverage of the Derby testing > ------------------------------------------------------------------------------------- > > Key: DERBY-3445 > URL: https://issues.apache.org/jira/browse/DERBY-3445 > Project: Derby > Issue Type: Improvement > Components: Build tools > Reporter: Vemund Østgaard > Assignee: Vemund Østgaard > Attachments: 3445-general-diff, 3445-testspecific-diff > > > It is a bit tricky to use EMMA to measure code coverage for the derby testing. > Modifications must be made to the source both to avoid problems with the SecurityManager and individual tests. It would be good if these modifcations could be done once and for all so that it was easier for anyone to run the tests with EMMA. > It would also be good to have ant tasks that would make it even easier to run the tests with EMMA. -- This message is automatically generated by JIRA. - You can reply to this email to add a comment to the issue online.
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Markus Untergassmair
TourismusMarketing Niedersachsen GmbH
Essener Str. 1
Hannover, 30173
Telephone: 4951127048822
Artfiles Hostmaster
Artfiles New Media GmbH
Zirkusweg 1
Hamburg, DE 20359
Telephone: 494032027290
Fax: 494032027295
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text: They did it months ago. They said they are in the dark as to why you haven't updated it. We are in the dark as well. It goes on sale now and then and more people get it, not realizing that it is the original DOS version run via ScummVM because other sites have the remastered version. The longer it sits, more people will enter into this issue. What real issues could there be with such a small game, especially after the first remastered Broken Sword went well? If there were real issues, wouldn't you have talked to Revolution about them? Come on, just update it.


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text: BARCELONA, Spain, Feb. 23, 2014 /PRNewswire/ -- Microsoft Corp. on Sunday announced nine new hardware partners for Windows Phone and direct access to tools that will broaden the portfolio of devices for consumers and introduce new price points to accelerate growth in key markets. In addition to existing partners — Nokia, Samsung, HTC and Huawei — Microsoft has announced it is now working with Foxconn, Gionee, Lava (Xolo), Lenovo, LG, Longcheer, JSR, Karbonn and ZTE to develop on the Windows Phone platform. (Logo: http://photos.prnewswire.com/prnh/20000822/MSFTLOGO) With this latest news, Microsoft is now working with seven of the top 10 smartphone manufacturers in the world in addition to leading brands in China, India and Taiwan, representing more than 56 percent of the addressable market globally (IDC Worldwide Mobile Phone Tracker, 2013). Customers can expect to see an even broader array of devices, from iconic to lower-cost options, coming to market. "We are pleased to add these new partners to our expanding Windows Phone ecosystem. They will be key contributors to continued growth across price points and geographies for Windows Phone," said Nick Parker, corporate vice president of the OEM Division at Microsoft. Windows Phone is the fastest-growing smartphone operating system, according to IDC, and posted the largest increase for 2013 (90.9 percent), more than doubling the growth of the overall market during the year. Microsoft also unveiled expanded hardware support that provides more flexibility so Windows Phone partners can build devices to meet the unique needs of their region or customer segments. Microsoft is adding support for Qualcomm Snapdragon™ 200 and 400 processors by Qualcomm Technologies Inc. with options that support various major cellular technologies, including LTE (TDD/FDD), HSPA+, EVDO and TD-SCMA. Windows Phone will also support soft keys and dual SIM, critical requirements particularly in Asian markets. These changes allow for manufacturing partners to easily leverage existing design investments to diversify their portfolio to include Windows Phone devices, including larger screen phablets.