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College of Charleston is small school with a very diverse group of students from all over the United States. Most of my classes were stimulating and rigorous. My professors were engaged and the majority of them were willing to meet with you and discuss questions / topics that were important to me. The campus is a beautiful, historic campus with old oaks dripping with moss. College of Charleston is in downtown Charleston, SC. The city is a tourist oriented city and there are restaurants everywhere and fun events going on constantly. I loved this school and recommend this school to all. You'll get a great balance of academics, new friends from all over the U.S., teachers who care, and an overall great education. I honestly cannot think of any great change to recommend. Certainly, there are a few teachers who are not stellar, but I the majority of the staff is fantastic!
I truly love the College of Charleston. There is an exuberant amount of programs available to students and faculty. Also, there is a plethora of major options. You can easily succeed at this school is you utilize the resources presented in front of you. Every day students receive emails about new and upcoming events and programs at the College. Teachers are also very helpful and friendly. They genuinely want their students to learn and succeed in each of their classes. Continuing, the College of Charleston is exactly in the middle of downtown Charleston. Students are constantly engulfed in culture and history. There is an exponential amount to learn while at the College of Charleston, inside and outside of the classes. Way to go College of Charleston!
The College of Charleston (CofC) is full of opportunity both for education and entertainment. Right in the heart of Downtown Charleston, CofC offers a stimulating environment full of unique restaurants and shops as well as well not commercialized stores and chains. CofC academics are strong, and as it is a liberal arts school, even the general education courses are a step above in difficulty and interest than in other like schools. CofC has wonderful professors who are passionate about their subject and who are supportive of each of their students. CofC is a safe, academically stimulating, vibrant, and overall top-notch educational institution.


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DiGiorno Is Actually Covering Its Social Media Screwup Pretty Well
Last night, twitter users were tweeting poignant and sad stories about domestic abuse under the hashtags #whyIleft and #whyIstayed, about their decisions to finally escape toxic living situations or to continue living in them. And then Digiorno tweeted this:
This is a common social media story - brands see trending hashtags and just throw something into the stream without necessarily looking at what the hashtag is in relation to. Entenmenn's tweeted about their "tasty treats" with a #notguilty hashtag, not realizing that it was related to the Casey Anthony verdict. Usually when brands embarrass themselves like this - like when Kenneth Cole tweeted that the unrest in Tahrir Square was due to its new spring collection - they just delete the tweet, hunker down, and wait for the storm to pass. DiGiorno, on the other hand, has actually addressed the screwup pretty directly. The person behind DiGiorno's social media account has been tweeted individual messages of apology at users for the last 12 hours.
This sort of thing will definitely happen again in the future. For the time being, DiGiorno has set the standard by which other companies should handle social media mistakes.

subset: commoncrawl


text: CASE REPORTS Serbian Journal of Dermatology and Venereology 2012; 4 (3): 105-112 DOI: 10.2478/v10249-012-0009-4 Linear porokeratosis: a case report Slobodan STOJANOVIĆ*, Marina JOVANOVIĆ, Nada VUČKOVIĆ, Milana IVKOV-SIMIĆ, Siniša TASIĆ 1 Clinic of Dermatovenereology, Clinical Center of Vojvodina, Novi Sad1 Center of Pathology and Histology, Faculty of Medicine, Novi Sad2 *Correspondence: S. Stojanović., E-mail: [email protected] UDC: 616.5-003.87-056.7-08 Abstract Porokeratosis is a rare genodermatosis based on chronic keratinization disorder histologically characterized by the presence of a cornoid lamella and various clinical manifestations. Five most commonly described types of poroketarosis are porokeratosis of Mibelli or "classic" porokeratosis, disseminated superficial actinic porokeratosis, disseminated palmoplantar porokeratosis, linear porokeratosis, and punctate porokeratosis. In all of the five clinical types of porokeratosis described today, cases of planocellular skin carcinoma are described, except in punctate type cases. Use of topical CO2 laser ablation, cryotherapy and topical use of 5% Imiquimod cream, have shown favorable effects in local treatment of porokeratosis. The authors present a clinical case of a girl suffering from linear porokeratosis over the course of the last four years, spreading on the inside of her right arm along the lines of Blaschko. Linear porokeratosis was histologically confirmed by biopsy of skin lesions and dermoscopy. Dermoscopic findings, used as an auxiliary method, also indicated linear porokeratosis. Successful liquid nitrogen cryotherapy prompted the authors to present a case in which the applied treatment proved to be successful, but also to emphasize the need for timely treatment in order to prevent malignant alterations of these changes. Key words Porokeratosis; Dermoscopy; Cryotherapy; Treatment Outcome T he "classic" type of porokeratosis (PK) was first described by Mibelli in 1983 (1, 2), as a condition which usually occurs in childhood, manifesting by one or several discreet keratotic plaques with desquamation, that may be present on any part of the skin and/or mucous membranes (3). That same year, Respighi described the disseminated superficial type of the disease, while the disseminated superficial actinic PK was described by Chernosky in 1967 (4). The linear type of PK was first described in 1918. In 1971, Guss was the first to describe the disseminated palmoplantar PK (5). In 1974, Rahbari defined linear PK as a separate form of the disease (6), and in 1977, the punctate PK was added to other clinical types (7). Porokeratosis is considered a genetic disorder characterized by autosomal dominant way of transmission, but most cases develop sporadically (8). Generally speaking, "classic porokeratosis" is more common in men, even up to 2-3 times, while the ratio in favor of males in cases of disseminated palmoplantar porokeratosis is 2:1. Disseminated superficial actinic porokeratosis is a female-predominant disease with a female to male ratio of 3:1 (8). According to data provided by The Singapore National Center, the incidence of linear PK, as a clinical type among different clinical types of the disease, is 12.9% and it is most commonly detected in the fourth decade of life (9). Linear type of PK is found/ in: monozygotic twins (10, 11) and families in which other types of PK are present (11, 12); its mode of transmission remains unknown (8, 11); the ratio of male to female porokeratosis cases is 1:1 and it is more common in Caucasians (11). Porokeratosis commonly affects extremities in the form of small, asymptomatic, distinct keratotic and/ © 2009 The Serbian Association of Dermatovenereologists Unauthenticated Download Date | 4/1/15 4:22 AM 105 S. Stojanović et al. Linear porokeratosis Serbian Journal of Dermatology and Venereology 2012; 4 (3): 105-112 or lichenoid papules or plaques, ranging from brown to skin color, and from one to several centimeters in diameter, with distinct keratotic edges and hypo-orhyperpigmented slightly depressed atrophic centers. Various skin changes can occur, but the ones typical for linear porokeratosis are localized, unilateral and follow the lines of Blaschko. Cases of malignant alterations have been reported in all 5 clinical types of PK, mostly planocellular skin carcinoma (PSC) within the porokeratosis lesions (8), except in cases of punctate type of PK (11). In this paper, the authors present a case of a young female patient with linear porokeratosis, present in the course of the last four years, affecting the inside of the right arm following the lines of Blaschko. Successful liquid nitrogen cryotherapy performed in the patient prompted the authors to present a case in which the applied treatment proved to be successful, but also to emphasize the need for timely treatment in order to prevent malignant alterations of these changes. Case report We present a case of a 27-year-old pharmacy student, otherwise healthy, who visited the Outpatient Clinic of the Clinical Center of Vojvodina in Novi Sad in 2009, with skin changes in the form of linear keratotic lesions running along the inside of her right arm. These changes first appeared four years earlier on the inside of her right humerus region, gradually spreading to the lower arm, without any subjective symptoms. After clinical examination, dermoscopy was performed, followed by skin biopsy of lesions. The diagnosis of linear porokeratosis was histologically confirmed. With the patient's consent, cryotherapy was applied to all skin lesions on her right arm. Complete regression of skin lesions occurred after 8 weeks of treatment. Personal history revealed that the patient never had any contraindications for liquid nitrogen cryotherapy. Family history revealed that none of her relatives had similar skin lesions or suffered from any kind of skin condition. There was no history of malignant tumors among immediate family members. Clinical examination showed that on the inside of the right arm, particularly on the 2/3 of the entire humerus and forearm, characteristic keratotic papules and/or small plaques were present, 0.5 to 2 cm in Figure 1. Linear porokeratosis; a) on the forearm b) on the upper arm and cubital fossa 106 © 2009 The Serbian Association of Dermatovenereologists Unauthenticated Download Date | 4/1/15 4:22 AM CASE REPORTS Serbian Journal of Dermatology and Venereology 2012; 4 (3): 105-112 diameter, oval to round shaped, with distinct edges separating them from the surrounding healthy skin, light to dark brown, with accentuated keratotic edges, hard in consistency, with slightly depressed, and a hypo- or hyperpigmented atrophic center. The lesions were located along the inside of the right arm, in a linear arrangement, running parallel within a distance of a few centimeters (Figures 1, and 2.). Figure 2. Linear porokeratosis: changes on the forearm (detail/close up) General examination of all organs and systems was regular. All the basic laboratory tests and biochemical results were within normal ranges. Histopathological examination revealed that the skin sample, stained by HE method (hematoxylin and eosin), PAS (periodic acid–schiff stain), and Gomori's and Giemsa methods, was affected by moderate epidermal hyperkeratosis and partial parakeratosis. In this region, epidermis was moderately thickened, with an angular keratotic layer towards the center of the lesion. Dyskeratotic cells were found in the middle layer along the zone affected by porokeratosis (cornoid lamella), while the granular layer of the epidermis was missing. Perivascular mononuclear cells were present in the papillary dermis. The remaining skin showed adequate and ageappropriate morphology (Figures 3. and 4.). Dermoscopy was performed using a manual dermatoscope Heine Delta 20 (Heine Optotechnik, Kientalsrasse 7, D-82211 Hersching, Germany) with 10 x magnification, using non-polarized light, after covering porokeratosis lesions with ultrasound gel. Dermoscopy showed round structures in the form of a "white line" along the edge of each porokeratosis lesion, which is a characteristic dermoscopic finding for porokeratosis. They were identified at the periphery of the lesion along with brown pigmentation on the inside and a double "white line" (arrow) in some parts of the lesion. Structures found in the form of a single or a double "white line" at the edge of the PK lesion histologically matched the cornoid lamella (Figure 5.) (13). Therapy was conducted using the open spray method with the Cry-Ac®-3 Brymill devices (Brymill Cryogenic Systems Bld 2. 105, Windermere Ave., Ellington, CT 06029 USA). The liquid nitrogen application lasted 30 seconds with a 2mm halo, in two cycles with a four-week period in between. Follow-ups were performed every four weeks combined with local application of an antibiotic cream. In addition to the usual post-therapeutic reactions, such as the appearance of small blisters and a light burning sensation during the first 48 hours following the treatment, no other objective and subjective symptoms were reported. After 8 weeks, there was a complete regression of the treated lesions (Figure 6.). © 2009 The Serbian Association of Dermatovenereologists Unauthenticated Download Date | 4/1/15 4:22 AM 107 S. Stojanović et al. Linear porokeratosis Serbian Journal of Dermatology and Venereology 2012; 4 (3): 105-112 Figure 3. Pathohistological finding: cornoid lamella angulated towards the center of the lesion (hematoxylin and eosin, x200) Figure 4. Pathohistological finding of linear porokeratosis: A column of parakeratosis (cornoid lamella indicated by an arrow) angulated towards the center of the lesion (indicated by a star); the underlying epidermis shows focal loss of the granular cell layer (hematoxylin and eosin, x10) 108 © 2009 The Serbian Association of Dermatovenereologists Unauthenticated Download Date | 4/1/15 4:22 AM CASE REPORTS Serbian Journal of Dermatology and Venereology 2012; 4 (3): 105-112 Figure 5. Dermoscopy finding of linear porokeratosis: characteristic annular whitish structure "white track" that sharply demarcates a central scar-like area with "double white track" (arrow) in some parts of the lesion (x10). Discussion Porokeratosis represents a whole spectrum of cutaneous/mucous clinical and morphological entities characterized by severe keratinization disorder, typical histological features and predisposition to development of cutaneous malignancies. The exact mechanism of carcinogenesis is still unknown, but it is assumed that the mediator in this process is increased expression of p53 gene, which was immuno-histochemically detected in skin changes of those suffering from porokeratosis (14). The presence of p53 mutations is probably a direct result of UV irradiation (11). Our case was one of linear porokeratosis located on the inside of the right arm in a spot directly exposed to sun during periods when short-sleeve and sleeveless garments are worn. As a genetically heterogeneous disorder, porokeratosis is characterized by histopathological changes and cornoid lamella formation, which increases the risk of skin cancer (11). At the same time, an important mechanism in the development of many types of cancer is the loss of allelic heterozygosity. Considering the fact that it was recently assumed that linear porokeratosis occurs also due to loss of allelic heterozygosity, it may be expected that linear porokeratosis lesions are particularly prone to malignant alteration. These results have been confirmed by certain studies (14, 15). According to literature data, planocellular skin carcinoma develops in the regions affected by linear porokeratosis (16). Critical review of skin cancer development within porokeratosis lesions showed an incidence of 7% (17). The literature describes different types of porokeratosis simultaneously affecting one person (12, 18) and immunosuppressed patients after renal or bone marrow transplantation, which refers specifically to the superficial type of the disease (19, 20). In our case, apart from clinical and pathohistological confirmation of the diagnosis, we additionally performed a dermoscopic examination of porokeratosis linear lesions and the obtained results were consistent with the ones previously published (13). Various therapeutic modalities that have been successfully applied in the treatment of linear porokeratosis do not favor any method for the time © 2009 The Serbian Association of Dermatovenereologists Unauthenticated Download Date | 4/1/15 4:22 AM 109 S. Stojanović et al. Linear porokeratosis Serbian Journal of Dermatology and Venereology 2012; 4 (3): 105-112 of timely therapy in order to prevent malignant alterations within the lesions and demonstrate favorable therapeutic effects of a simple and widely available method of cryotherapy. References: Figure 6. Linear porokeratosis after local cryotherapy being (3, 9, 11). The efficacy of systemic therapy of PK with Etretinate or retinoids has been previously described (3, 21, 22). In the case described herein, local cryotherapy has proven effective, which was confirmed by the results of other authors (23, 24). Photodynamic therapy has also proved effective (25) as well as local use of CO2 laser and Imiquimod cream application (26, 27). Conclusion In the presented case of linear porokeratosis, which is a rare genokeratosis, the authors emphasize the necessity 110 1. Mibelli V. Contributo alla studio della ipercheratosi dei canali sudoriferi (porokeratosi). G Ital Dermatol Venereol 1893:28:313-55. 2. Happle. Mibelli revisited: a case of type 2 segmental porokeratosis from 1893. J Am Acad Dermatol 2010;62:136–8. 3. Mehta V, Balahandran C. Simultaneous co-occurence of porokeratosis of Mibelli with disseminated superficial actinic porokeratosis. Indian J Dermatol 2009;54(4):390–1. 3. Judge MR, McLean WHI, Munro CS. Disorders of Keratinization. In: Burns T, Breathnach S, Cox N, Griffiths C, editors. Rook's Textbook of Dermatology. 6th ed. Oxford: Blackwell Publishing Ltd; 2010. pp. 19.1-121. 4. Chernosky ME, Freeman RG. Disseminated superficial actinic porokeratosis (DSAP). Arch Dermatol 1967;96:611–24. 5. Guss SB, Osbourn RA, Lutzner MA. Porokeratosis plantaris, palmaris, et disseminata: a third type of porokeratosis. Arch Dermatol 1971;104(4):366-73. 6. Rahbari H, Cordero AA, Mehregan AH. Linear porokeratosis: a clinical variant of porokeratosis of Mibelli. Arch Dermatol 1974;109:526-8 7. Rahbari H, Cordero AA, Mehregan AH. Punctate porokeratosis: a clinical variant of porokeratosis of Mibelli. J Cutan Pathol 1977;4:338-41. 8. Zdelar D. Porokeratoza. U: Karadaglic Đ. Dermatologija. Beograd: Vojnoizdavački Zavod; 2000. Str. 482-8. 9. Leow YH, Soon YH, Tham SN. A report of 31 cases of porokeratosis at the National Skin Centre. Ann Acad Med Singapore 1996;25(6):837-41. 10. Malhotra SK, Puri KJ, Goyal T, Chahal KS. Linear porokeratosis. Dermatol Online J 2007;13(4):15. 12. Murase J, Gilliam AC. Disseminated superficial actinic porokeratosis co-existing with linear and verrucous porokeratosis in an elderly woman: Update on the genetics and clinical expression of porokeratosis. J Am Acad Dermatol 2010;63:886-91. 13. Delfino M, Argenziano G, Nino M. Dermoscopy for the diagnosis of porokeratosis. J Eur Acad Dermatol Venereol 2004;18:194-5. 14. Arranz-Salas I, Sanz-Trelles A, Ojeda DB. p53 alterations in porokeratosis. J Cutan Pathol 2003;30(7):455-8. 15. Happle R. Cancer proneness of linear porokeratosis may be explained by allelic loss. Dermatology 1997;195(1):20-5. 16. Lozinski AZ, Fisher BK, Walter JB, Fitzpatrick PJ. Metastatic squamous cell carcinoma in linear porokeratosis of Mibelli. J Am Acad Dermatol 1987;16(2 Pt2):448-51. 17. Goerttler EA, Jung EG. Porokeratosis of Mibelli and skin carcinoma: a critical review. Humangenetik 1975;26(4):291-6. 18. Mehta V, Balahandran C. Simultaneous co-occurence of porokeratosis of Mibelli with disseminated superficial actinic porokeratosis. Indian J Dermatol 2009;54(4):390–1. 19. Knoell KA, Patterson JW, Wilson BB. Sudden onset of disseminated porokeratosis of Mibelli in a renal transplant © 2009 The Serbian Association of Dermatovenereologists Unauthenticated Download Date | 4/1/15 4:22 AM CASE REPORTS Serbian Journal of Dermatology and Venereology 2012; 4 (3): 105-112 patient. J Am Acad Dermatol 1999;41(5 Pt 2):830-2. 20. Andrew FA, Busam K, Myskowski LP. Porokeratosis of Mibelli following bone marrow transplantation. Int J Dermatol 2006;45: 361–5. 21. Goldman GD, Milstone LM. Generalized linear porokeratosis treated with etretinate. Arch Dermatol 1995;131(4):496-7. 22. Hong JB, Hsiao CH, Chu CY. Systematized linear porokeratosis: a rare variant of diffuse porokeratosis with good response to systemic acitretin. J Am Acad Dermatol 2009;60(4):713-5. 23. Bhushan M, Craven NM, Beck MH, Chalmers RJ. Linear porokeratosis of Mibelli: successful treatment with cryotherapy. Br J Dermatol 1999;141(2):389. 24. Dereli T, Ozyurt S, Ozturk G. Porokeratosis of Mibelli: successful treatment with cryosurgery. J Dermatol 2004;31(3):223-7. 25. Cavicchini S, Tourlaki A. Successful treatment of disseminated superficial actinic porokeratosis with methyl aminolevulinate-photodynamic therapy. J Dermatol Treat 2006;17:190–1. 26. Harrison S, Sinclair R. Porokeratosis of Mibelli: successful treatment with topical 5% imiquimod cream. Australas J Dermatol 2003;44(4):281-3. 27. Montes-De-Oca-Sanchez G, Tirado-Sanchez A, GarciaRamirez V. Porokeratosis of Mibelli of the axillae: tretatment with topical imiquimod. J Dermatol Treat 2006;17(5):319-20. Porokeratoza Sažetak Uvod: Porokeratoza predstavlja retku genodermatozu u čijoj osnovi se nalazi hronični poremećaj keratinizacije sa karakterističnim histološkim nalazom kornoidne lamele i različitim kliničkim ispoljavanjem. Naj-češče se opisuje 5 tipova porokeratoze: "klasična" porokeratoza Mibelli, diseminovana superficijalna aktinička porokeratoza, diseminovana palmoplantarna porokeratoza, linearna porokeratoza i punktatna porokeratoza. U svim do danas poznatim kliničkim tipovima porokeratoze, opisani su slučajevi nastanka planocelularnog karcinoma kože, izuzev kod punktatnog oblika. U lokalnoj terapiji porokeratoze, povoljan terapijski efekat su ispoljili: CO2-laser, krioterapija i lokalna primen 5% imikvimod krema. Prikaz slučaja: Autori prikazuju slučaj devojke sa linearnom porokeratozom prisutnom tokom poslednje četiri godine, koja je zahvatila desnu ruku sa unutrašnje strane, pružajuči se duž Blaškovih linija. Nalaz linearne porokeratoze potvrđen je histološki posle uzete biopsije kožnih promena, a urađen je i pregled metodom dermoskopije. Dermoskopski nalaz, kao pomoćni dijagnostički metod, takođe je ukazivao na linearni oblik porokeratoze. Uspešna krioterapija tečnim azotom, koja je sprovedena kod bolesnice, navela je autore da prikažu ovaj slučaj u kome se primenjena metoda lečenja porokeratoze pokazala uspešnom, ali i da bi istakli potrebu blagovremene terapije porokeratoze sa ciljem prevencije maligne alteracije u ovim promenama. Diskusija: "Klasičan oblik" porokeratoze (PK) prvi je opisao Mibelli 1893. godine (1, 2) kao oboljenje koje se obično pojavljuje u detinjstvu u vidu jednog ili nekoliko diskretnih keratotičnih plakova sa deskvamacijom, koji se mogu pojaviti na bilo kom delu kože i/ili sluznicama (3). Respighi iste 1893. godine opisuje diseminovani superficijelni oblik PK, a 1967. godine Chernosky daje detaljan opis diseminovane superficijelne aktiničke forme bolesti (4). Linearni oblik PK prvi put je opisan 1918. godine. Guss 1971. godine prvi opisuje diseminovanu palmoplantarnu PK (5). Rahbari 1974. godine izdvaja linearnu PK kao posebnu formu bolesti (6), a 1977. godine kliničkim oblicima PK dodaje punktatni oblik (7). PK se smatra naslednom bolesti sa autozomnodominantnim načinom prenosa, ali najveći broj slučajeva nastaje sporadično (8). Inače, "klasična" PK je češća kod muškaraca, čak 2-3 puta, dok je kod palmoplantarne diseminovane PK odnos muškarci : žene − 2:1. Kod diseminovane aktiničke PK postoji predominacija ženskog pola nad muškim u odnosu 3:1 (8). Učestalost linearne porokeratoze kao kliničkog oblika među svim ostalim kliničkim oblicima porokeratoze prema podacima Nacionalnog centra u Singapuru iznosi 12,9 % i obično se otkriva u četvrtoj deceniji života (9). Linearni oblik PK je nađen kod monozigotnih blizanaca (10, 11) i u porodicama u kojima su istovremeno prisutni i ostali oblici PK (11, 12); ostaje nepoznat način prenošenja (8, 11 ); odnos polova je 1:1 i češći se javlja kod pripadnika bele rase (11). PK najčešće zahvata ekstremitete u vidu malih, asimptomatskih, keratotičnih i/ili lihenoidnih papula ili plakova smeđe do boje kože, koji su oštro ograničeni, © 2009 The Serbian Association of Dermatovenereologists Unauthenticated Download Date | 4/1/15 4:22 AM 111 S. Stojanović et al. Linear porokeratosis Serbian Journal of Dermatology and Venereology 2012; 4 (3): 105-112 promera jednog do nekoliko centimetara, sa naglašenom keratotičnom ivicom tvrde konzistencije sa hipopigmentovanim ili hiperpigmentovanim centrom koji se lako uleže; atrofičnog je izgleda. Kod linearne PK mogu nastati multiple promene, zatim lokalizovane i unilateralne, slede Blaškove linije na koži. U svim do danas danas poznatim kliničkim tipovima PK, opisani su slučajevi maligne alteracije i nastanka, najčešće planocelularnog karcinoma kože (PCK) u lezijama PK (8), izuzev kod punktatnog oblika (11). Zaključak: U ovom radu, autori prikazuju slučaj devojke sa linearnim porokeratozom, prisutnom unazad četiri godine, koja je zahvatila desnu ruku sa unutrašnje strane, pružajući se duž Blaškovih linija, da bi istakli potrebu blagovremene terapije porokeratoze radi prevencije maligne alteracije u ovim promenama. Ključne reči Porokeratoza; Dermoskopija; Krioterapija; Ishod lečenja 112 © 2009 The Serbian Association of Dermatovenereologists Unauthenticated Download Date | 4/1/15 4:22 AM


text: MERRIAM, Kan., Oct. 1, 2012 /PRNewswire/ -- Today, Lee National Denim Day kicks off National Breast Cancer Awareness Month with one important goal – raising critical funds for American Cancer Society breast cancer research and support programs. Thousands of people nationwide will choose a day in October to celebrate Denim Day by wearing their jeans and donating $5 to the cause. Since its inception in 1996, Denim Day has raised more than $86 million to fight breast cancer. With the American Cancer Society as this year's Denim Day beneficiary, funds raised will support life-saving screenings in communities nationwide; provide a free place to stay for those traveling away from home for cancer treatment; and invest in groundbreaking cancer research. Leading the effort is Lee National Denim Day's 2012 survivor ambassador Debbie Howe. Forty-six year-old Howe began treatment six months ago when she was diagnosed with breast cancer. When she underwent a double-mastectomy that failed to eliminate the cancer, she began chemotherapy treatments. Howe relies heavily on her team of family and friends for support and to help her rise above breast cancer. Every day, the American Cancer Society provides information, day-to-day help and emotional support for cancer patients. This year, Lee National Denim Day hopes to contribute millions to the American Cancer Society in the fight to end breast cancer. "I'm grateful for the work being done by Lee National Denim Day," says Howe. "During the darkest part of my life, it helps to know that there are so many people out there working to make a difference for me and the millions of others diagnosed with breast cancer." Fifty percent of net proceeds raised through Lee National Denim Day will benefit community-based programs, including breast cancer screenings and the Society's Hope Lodge ® initiative, which provides cancer patients and their families a free place to stay when they have to travel away from home for treatment. In 2011, Hope Lodge facilities across the country provided approximately 250,000 nights of free lodging to nearly 38,000 patients and caregivers – saving them nearly $23 million in lodging expenses. The remaining proceeds of Lee National Denim Day will help fund the American Cancer Society's national research grants to find cures for breast cancer. As the largest private, not-for-profit funder of cancer research, the Society has contributed to nearly every cancer breakthrough in recent history. Their funded researchers have helped develop the drugs to treat advanced breast cancer and have shown that mammograms are the most effective form of detection. One in every two women newly diagnosed with breast cancer reaches out to the American Cancer Society for help and support.


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Not My DayMature
Katrina "Sidewinder" Mojave
The largest compulsion to hit someone burned from within me. This...day...couldn't... get...any...fucking...worse! The helicopters damaged rotors whined at me, alarms clanging and men howling in anger and fear. It had all gone so wrong, why couldn't I go back to that hanger a day ago. Where Hornet, Duke, and I were tossing back shots. At least then my life didn't feel like a total shit storm.
It all began after the Army helo had picked me up and hauled off towards the mountains. Apparently the airbase, one of our last bastion's of hope torn from our grasp by the filthy Chinese. The air around us whistled, the tops of the trees barley missing the wheels below the craft. It was either fly low and try to avoid the fighting jets above or go and get shot down. Either way, we were a rat in a snake pit and the odds of getting out fell with every second we lingered in the combat zone. The Uh-60 helo trembled and groaned as it's pilot pushed the machines throttle as hard as it would take us.
"Your one lucky pilot ma'am," the co-pilot shot back at me as he refocused on the GPS designator on the dash. A small blue line on the screen marked our front line, red masses encroached further into the blue. If we didn't find some advantage over the Chineses' innumerable soldiers, the war would be over in less than a months time.
"Godhand, this is Seagull! We have Sidewinder on board and are sprinting to the regroup point we-" I interrupted the conversation, pulling on a comm helmet and practically shouting to the AWACS monitoring plane.
"This is Sidewinder, I wann know what the fuck is going on with my squadron! Where are they?" The line buzzed, occasionally hissing with static until AWACs replied sharply.
"Duke was shot down deep behind enemy lines and is assumed dead..." Dead?! I felt the bottom of my stomach fall away as a burning guilt clutched me tightly. What had been my last words? Was I shouting, did I say how much I appreciated him? I didn't even get to say good bye. Biting my lips hard, the helicopter banked to the right and I spoke again.
"What about Hornet?" My voice was much more worried and pained that I had wanted to show. This, of all times, wasn't the place to show emotions that weren't needed on the battle field. With Duke assumed dead, Hornet was all I had left. I felt desperate and like a failure.
"He's alive, our radars have him trailing at 1000 meters, heading to where all forces are regrouping we're going to make one last push fr-" the comm shut down as bullets riddled the aircraft and the tell tale scream of jet engines echoed behind us.
"SHIT!" the pilot spat, steering the chopper to the far right, left and back. More bullet's peppered the hull until the pilot slumped dead in an explosion of blood. The crimson liquid smeared across the windscreen. A loud thud noise and an explosion rattled the aircraft sending us into a tailspin through the air. The engine whined, alarms blared, and the co-pilot shouted...we were going down.
So now you know why officially just want to end this day, I almost took a cynical approach to the crashing bird. Anticipating the crash as the thump of the rotors grew heavier and heavier, we nearing the ground at increasing speeds. The G-forces pinned me back in my seat, straining the belt strapped across my body. Over my helmet, I triggered the comms channel.
"This is Sidewinder, to any aircraft in the area. We're fucked and going down. I need immediate evacuation to the rally point. Hurry the fu-" My head smashed against the Helo's metal skin, knocking me out before the helicopter dropped into the ground.
Regaining consciousness, I heard footsteps nearing me. I tried to roll over but my aching body protested. The pistol on my side, hovered on the edge of my vision. Tossed from it's holster, it sat just to my right near the burning and twisted wreckage of the Army helicopter. The steps drew closer, crunching on leaves and twigs. From the sound I could tell there was more than one. Instantly, my arm reached out and snapped up the pistol into my grip.
"Fucking freeze," I shouted, my mouth dry and my tongue rough as sandpaper. The movements stopped. "Thunder!" I shouted the code to identify friendlies...silence. Sweat began to pour down my brow as my body trembled from surviving two crashes.
"Storm," Came the reply as three Marines stepped like ghosts from the forest brush. I didn't relax my grip on the pistol, using my elbow to prop myself up. "Easy Lt, I'm Staff Sergeant Hicks...we're with First Marine Recon." I raised an eyebrow, letting the pistols aim drop a small amount. "We're here to get you back to regroup point." I sighed heavily and tried to stand, hearing a small explosion echo not too far off.
"Ma'am we need to go now!" One of the other Marines said quickly. "The Chinese are closing in." I stood, gasping and biting back a painful scream as blood ran from my forehead and other parts of my body. A large gash rested over my thigh, were a large chunk of shrapnel had torn through my flight suit. Two of the Marine rushed over, supporting me as we hurried to their helo, a more heavily armored craft that i had always known as a "Jolly Green Giant." The craft jumped into the air as Chinese soldiers rushed into the clearing, firing and shouting.
"Your one lucky bastard, Lt." One of the Marines said, calming his heavy breathing. I shook my head and pressed my palm into the large gash...hoping to stop the bleeding as best I could.
"No, I'm just to stubborn to die when I'm supposed to..." I trailed off, wincing again as more pain throbbed, this time behind my eyes. "You guys got a radio I can use?" Hicks nodded and passed me a comms helmet.
"Hornet?" I asked wearily. Nothing..."You still alive, remember you can't die on me. Duke, you, and I are celebrating when this war is over remember? All of us getting slammed on shots..." I stifled my emotions at the mention of both their names, praying to no one in particular that I would hear that familiar voice.


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Bixby's Back ´2011
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- Writers: Steven Levitan, Christopher Lloyd
- Stars: Ariel Winter , Aubrey Anderson-Emmons , Ed O'Neill , Eric Stonestreet , Jesse Tyler Ferguson , Julie Bowen , Nolan Gould , Rico Rodriguez , Sarah Hyland , Sofía Vergara , Ty Burrell
In an attempt to avoid turning into that old boring couple, Phil and Claire decide to revisit their Clive and Juliana role-playing rendezvous from last Valentine's Day. Meanwhile Jay has planned an elaborate surprise evening for Gloria, but his plans keep getting thwarted, and an admirer comes between Cameron and Mitchell on V-day, but they can't agree whom the admiration is directed towards.
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