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Stanford Scientists Use Copy/Paste Method to Make Cells HIV Resistant
Tiffany Kaiser
January 24, 2013 8:59 AM
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HIV virus
(Source: gizmag.com)
The method stopped HIV from entering healthy immune cells
Stanford scientists have found a way to protect the immune system from HIV by
placing resistant genes into T cells
Researchers from the Stanford University School of Medicine, led by Matthew Porteus, MD, have used a cut and paste method where HIV-resistant genes were coupled with T cells to deny the virus' entry into healthy immune cells.
The HIV virus typically enters immune cells by binding to one of two surface proteins: CCR5 and CXCR4. However, some people have a mutation in CCR5 that makes them resistant to HIV.
Porteus and his team used this idea to create a method for making this protein inactive. They used a protein, called a zinc finger nuclease, that finds and attaches to the CCR5 receptor gene and modifies it to imitate the mutated, inactive versions. It does this by breaking up pieces of DNA.
In addition to breaking a sequence in the CCR5 receptor's DNA, the team pasted three genes that are resistant to HIV. They help protect the cells via both the CCR5 and CXCR4 receptors. This technique is called stacking, where multiple layers of protection are used to protect the cells.
In tests, T cells with single, double and triple gene modifications were protected against HIV. However, as expected, the triplets were much more resistant to infection. In fact, they had 1,200-fold
protection against HIV
carrying the CCR5 receptor and 1,700-fold protection against those carrying the CXCR4 receptor.
T cells without any protection were infected within 25 days.
"We inactivated one of the receptors that HIV uses to gain entry and added new genes to protect against HIV, so we have multiple layers of protection -- what we call stacking," said Porteus. "We can use this strategy to make cells that are resistant to both major types of HIV."
There are two issues that the team has to work out, though. First, the zinc finger nuclease could cause a break elsewhere in the DNA and cause cancer. Second, the cells may not accept the genetic change.
Science Daily
Stanford School of Medicine
"I'd be pissed too, but you didn't have to go all Minority Report on his ass!" -- Jon Stewart on police raiding Gizmodo editor Jason Chen's home
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FRAMINGHAM, Mass. (AP) — President Barack Obama's uncle plans to argue that Massachusetts police did not have the right to stop his car before his drunken-driving arrest.
A lawyer for Onyango (ohn-YAHN'-goh) Obama told a judge Thursday he plans to file a motion to suppress the traffic stop that led to his client's arrest in August because Obama was not committing any motor vehicle violations.
Obama has pleaded not guilty. He did not speak during the brief appearance in Framingham District Court.
A hearing on his lawyer's suppression request is scheduled for Jan. 12.
Obama is the half brother of the president's late father.
He was initially held without bail on a detainer from U.S. Immigration and Customs Enforcement officials on allegations he violated an order to return to Kenya, but has since been released.

subset: commoncrawl


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Marketing small business is topic of SBDC series segment
"Marketing Your Small Business" is the third in the spring Advantage Series presented by the Small Business Development Center (SBDC) in the Business and Industry Center at Central Lakes College (CLC) in Brainerd.
From 6-7:30 p.m. Feb. 12 in Room E151 at CLC, Jay Bock will review traditional methods of marketing, what part social media should play in your marketing plan, and how a business decides where their marketing dollars should go.
This session will also talk about determining your target market and how you will reach them with your advertising. This session is for anyone thinking of starting or purchasing a business, CLC reports.
This session is also for those who have a small business and have a social media fear. Come and learn what the buzz is about and how sales may be increased.
The Advantage Series offers four 1.5-hour sessions to help participants be better prepared if they are looking to start a business. Some of these sessions are helpful for those already in business. Attend one or attend the whole series. Take them in any order.
Follow-up counseling is available from the Small Business Development Center's team of consultants at no-charge.
Upcoming sessions: accounting tools, and business planning.
Admission is $30 per person for each session or $100 per person for all four in the series.
Registration deadline is seven days prior to the class date. For more information to to http://clcmn.augusoft.net/ or contact Julie Platta at 855-8140 or firstname.lastname@example.com.


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Name as it appears on the ballot: Anthony G. Forlini
Office you are seeking, including district number:
Michigan House of Representatives District 24
Date of birth: 2/4/1962
Occupation: Harrison Township Supervisor 2004-present (currently in second term)
Certified Financial Planner for 28 years
Small business owner in Mount Clemens
How long have you lived in your district?
39 years (grew up in St. Clair Shores, have lived in Harrison Township for 23 years)
Affiliations/Community Involvement:
Board Member - St. John North Shores Hospital Foundation
Charter President of Southeast Michigan Chapter of Western Michigan University Alumni Association
Past Senior Vice President of Italian American Cultural Center
Past Board Member - Macomb County Chamber of Commerce
Past Youth Co-Leader - St. Hubert Catholic Church
Past Grand Knight - St. Hubert Knights of Columbus
Have you run for or held a public office before? When?
Harrison Township Supervisor 2004 & 2008
website: www.AnthonyForlini.com
Message to voters (400-500 words):
This is the community where I have lived, raised a family and grown a business. As a business owner, I understand the need to create a responsible tax system that attracts new business, creates jobs and improves our standard of living. As a Township Supervisor, I traveled at my own expense with a bipartisan group to China to attract new industry and new jobs to our area; I've spoken out on local water quality issues; and I've worked to expand the Macomb County bike path for residents' enjoyment and to promote tourism. As the father of three college-age children, I now fear the heartache that other Michigan parents and grandparents have experienced as our children leave for jobs in other states. This exodus of talented young adults damages families and the Michigan economy. I want to work to make Michigan the "land of opportunity" that it was when my father, a European immigrant, settled in St. Clair Shores over 50 years ago. We can no longer settle for the timid reforms or half-hearted reorganizations that have been proposed by the Michigan legislature. Michigan needs a comprehensive strategic plan to attract new jobs, get spending under control and create a budget that eliminates waste and assures that our tax dollars are allocated to residents' priorities. I am confident that my resume reflects the diverse experience needed to transform our state government and to cultivate a globally competitive economy that makes Michigan a "Top Ten" state again. I will welcome the opportunity to use my experience in the private and public sectors to create new models for economic development, education, health care, the environment and the other issues that will best serve our state's citizens.


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The popular Twitter client for Windows 8, glƏƏk! has received an update to add yet more functionality to the app. Fans of Microsoft's OneNote will rejoice at the integration glƏƏk! now has with the note-taking service. Ever felt like saving tweets (or even trends) to OneNote for further analysis/reading? Now you can in glƏƏk!.
Pre-order: Surface Laptop


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Like estrogen loss in older women, decreased levels of testosterone may put aging men at risk for Alzheimer's disease, according to a new study by USC researchers.
The team's findings – appearing as a letter to the editor in the Sept. 22 issue of the Journal of American Medical Association – bolster sparse research on the adverse effects of age-related testosterone depletion in the brain and may lead to future development of hormone replacement therapies.
"Our findings strongly suggest that normal age-related testosterone depletion is one of the important changes that promote Alzheimer's disease in men," said Christian Pike, senior author of the study and an assistant professor at the USC Leonard Davis School of Gerontology.
"Understanding how these changes increase vulnerability to the disease is critical not only for elucidating Alzheimer's development, but also for identifying those persons most at risk," Pike said.
While the link between estrogen loss in women and increased susceptibility to a variety of diseases – including Alzheimer's – has long been well established, there has been less focus on the health effects of hormonal depletion in men.
Only within the last few years has the range of impairments – including osteoporosis and the loss of muscle mass, strength and function known as sarcopenia – linked to decreased testosterone levels become a recognized clinical syndrome called ADAM, or androgen deficiency in aging males. Androgens are male sex hormones.
The data collected by the USC team – Pike, Lilly Chang and Frank Stanczyk of the Keck School of Medicine of USC, and Emily Rosario of the USC Andrus Gerontology Center – suggests that the brain is another tissue that experiences age-related testosterone loss and that increased vulnerability to Alzheimer's disease should now be considered a component of ADAM.
Using brain tissue from 45 (previously consenting) deceased male subjects and an established medical scale of neuropathology, the researchers divided their samples into three categories: those considered neuropathologically normal with no clinical history of cognitive impairment (these were the controls); those who exhibited mild neuropathological changes; and those who had Alzheimer's disease.
"We found that brain levels of testosterone are significantly lower in [Alzheimer's] subjects compared with the control subjects," the researchers wrote. "We found that brain levels of testosterone are also significantly reduced in men with mild neuropathology consistent with early Alzheimer's disease."
Furthermore, the team demonstrated that estrogen levels in the subjects' brains were affected by neither advancing age nor the presence of Alzheimer's disease.
"Thus far, our research tell us that testosterone has at least two critical brain functions relevant to Alzheimer's disease," Pike said. "It protects neurons from injury, and it reduces levels of beta-amyloid, the protein widely implicated as a causal factor in the disease."
"We believe that the loss of testosterone with advancing age creates a more hostile neural environment that promotes accumulation of toxic beta-amyloid protein while leaving neurons less able to survive the insult," he added.
Alzheimer's disease, first described in 1906 by German physician Alois Alzheimer, involves the degeneration of nerve cells in the cerebral cortex and hippocampus, restricted parts of the brain associated with memory.
The national Alzheimer's Association estimates that the disease currently affects approximately 4 million Americans, half of which are men. By the year 2050, it is predicted that an additional 10 million could suffer from the illness.
And much more research remains before a cure can be found.
Pike and his colleagues seek to determine the mechanism by which testosterone depletion places the brain at increased risk for the mentally debilitating disease.
"Advancing age is the most significant risk factor for Alzheimer's disease," Pike said. "We now have to find the age-related changes that combine to promote the disease."
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Find the Right Spot
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Tray: Nickel Plated Trays, set of two, $142; mothology.com
Carafe: Glass Half Full Carafe, $34; wisteria.com


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|incl. VAT
|£7.19 £6.79
|excl. VAT
Develop creativity and spatial perception of your children. The packing kits, refer to 24 pieces consisting of magnetic rods and spheres. Your kids will surely find pleasure in the endless possibilities of this kit. The pieces can be combined in almost any way. Designers can model and create all sorts of it, for example, a helicopter, a house or a human skeleton. Smaller children can practice the fine mechanics and creativity in building basic models. Older children are tested its attention to detail and knowledge. DNA code, cosmic or human skeleton model can be assembled. And how else to learn the complex curriculum material before attempting a game.
Specifications can be changed without notice. Images are for illustrative purposes only. Retail Price (MSRP) means the manufacturer's/supplier's suggested retail price.
Link to Manufacturer's Website: Enter link to the external review


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[4.1.0] Pet Skills & Micro-Management
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Post by
Looks like this will be the only pet guide on this forum that will get 4.x updates. With that in mind, I may expand the scope of this guide, but no promises.
I highly recommend
for anyone who wants to learn the basics of hunter pets, find a new hunter pet, etc. It's a phenomenal resource.
Hunters are heavily reliant on their pets. Memories of Cialbi being chased by
big bad trolls
up and down Coldridge Valley as a baby dwarf without a pet reinforces this in my mind (this being back when hunters had to wait until level 10 to get pets). All other classes, save Warlocks and Unholy Death Knights, have to manage one character in battle. We have two, and one of them is partially controlled by an imperfect AI. So, in order to let us focus on our hunter's shot priority and rotation, Blizzard gave us an autocast tool for many of our pets' abilities. However, this makes it easy to forget about our pets, and how to properly manage them. Fortunately, the autocast functions, a few abilities readily available to be clicked on or even hotkey'd, and a macro or two will suffice for pet management in all but the most extreme circumstances (i.e. soloing Burning Crusade raids). I will focus on how to manage your pet's abilities; giving you the details necessary to make your own judgment calls.
Rule of Thumb on Growl
Setting Up Your Pet Actionbar
Essay - Understanding Focus
Toggling Autocast on Pet Abilities
Pet Abilities - The Autocast List
Pet Abilities - No Autocast
Pet Stable or Raid Toolbox? - A guide to which pets cover which raid buffs & debuffs
All Other Pet Special & Exotic Abilities
Pet Management Tips & Tricks
PvE DPS (includes pet specs!)
Mini-Guide on Extreme Soloing & Pet Tanking
Pet choices
Talent specs
Generic strategies
Post by
Rule of Thumb on
These is a cardinal sin that I feel should be singled out for every hunter to learn.
is one of the biggest sources of friction in a party. It is an ability that every hunter pet has upon being tamed. It does absolutely no damage; Growl is solely for producing threat. There have been debates raging now and then on this forum. Simply put,
Growl is never to be on autocast while in a group unless your pet is tanking for whatever reason
. At lower levels Growl can create more threat than (same level) tanks can compensate for. When not in a group, Growl is always a good idea. Your pet can take a beating far better than you can - you can heal your pet, but your pet cannot heal you.
This can all be accomplished by a few lines in one or more of your macros:
/petautocastoff Growl
/petautocaston Growl
I have this in my Hunter's Mark macro; it's personal preference. If you want options, then a /stopmacro line will suffice. However, I want to keep this clear and simple.
Setting Up Your Pet Actionbar:
When you tame a pet, a ten-slot pet actionbar will appear with some pet abilities listed. As of 4.0.1, this actionbar is fully customizable. You should take advantage of this. First off, you'll want to leave Attack, Follow, Move To, Defensive, and Passive in place. Go ahead and remove Aggressive so as to free up room. remove the four pet abilities that are placed in the middle of the actionbar as well. This gives you 5 slots to put pet abilities into. I would recommend putting Growl into one of those slots, so as to have a quick reference to check if the ability is on autocast or not. Depending on your pet, you may want to put certain Special, Exotic, and/or Bonus Abilities onto the pet actionbar as well. Some abilities that your pet talents into that you may want on your actionbar include Taunt, Roar of Sacrifice, Roar of Recovery, Call of the Wild, and Heart of the Phoenix. Beyond that, it's personal preference.
Essay - Understanding Focus:
I've kindly included a
at the bottom for those of you who find an essay by a science major to be as dry as sand.
Ever since patch 4.0.1 went live, the importance of properly understanding the mechanics behind Focus and how it affects your DPS is all the more imperative. In short, neither you nor your pet want to be at full Focus while in combat if you can help it, as that is most certainly a DPS loss.
A very handy analogy is a bucket sitting under a continually running faucet. You want to use as much of the water as possible, and as efficiently as possible. If you let your bucket get filled to the brim, the water will overflow, and the overflowing water gives you 0 benefit. Hence, you want some way to 'dump' water that still gets some use out of it if nothing else. This is the idea of a Focus dump. For us hunters, our Focus dump is Arcane Shot - we use it to get rid of Focus when we have no better way to spend our Focus. For our pets, they rely upon their Basic Attack to dump Focus. Depending upon the pet, this will either be
, or
(the difference between them is purely aesthetic). In fact, the Basic Attack is for most pets the only ability that uses Focus to do direct damage. For this reason, and the fact that pets' Basic Attack has a set 3 second CD, the
rank 2
) talent that is found on all three pet talent trees was changed in order to create a more flexible system where buildups of focus surplus aren't wasted but rather used quickly with Basic Attacks that use more focus and do even more damage.
So, to better understand how our pets function, we look at how their Basic Attack affects their Focus regeneration. Given the short cooldown on this ability, your pet will rarely have more than 25 Focus when in combat with their Basic Attack on autocast. With a Focus regeneration rate of 5 Focus per second on our pets, the only way our pets will find themselves above 25 Focus is through
procs. Thus, when your pet is in combat, and has the Basic Attack enabled, don't count on your pet being able to use any abilities with a Focus cost higher than 25 except when entering combat with full Focus. However, those abilities are limited to
- both of which are used to get your pet into combat quickly and have little use beyond that. Thus, having your pet's Basic Attack on autocast is always a good idea.
Here's where it gets sketchy. With Wild Hunt, your pet gets two empowered Basic Attacks before running out of Focus. If your pet uses Dash/Dive or Charge/Swoop, that gets limited to one empowered Basic Attack. Finally, if you have a Ferocity pet with Dash/Dive, Charge/Swoop
Wild Hunt, you're doing it wrong - you are wasting a talent point no matter how you work it out (Note: if you have both Dash/Dive and Charge/Swoop active on your pet, it will cast Dash/Dive first since it will most likely start out at max range, then follow up with Charge/Swoop the moment it comes into range). Keep this in mind when speccing a Ferocity pet.
TL;DR: Don't let focus reach 100% on either your pet or yourself while in combat if you can help it, keep your pets Basic Attack (
, or
) on autocast, and don't talent a Ferocity pet for
at the same time.
Back to Table of Contents
Post by
Toggling Autocast on Pet Abilities:
Some of the pet abilities below have a note advising against leaving them on autocast. However, many pet abilities are on the pet GCD, meaning that you have to spam some pet abilites that are off autocast to finally get your pet to actually use the ability. This is an unnecessary distraction, and creates a delay that you may not afford. Thus, for abilities that are on the pet GCD, I suggest instead putting the ability on autocast temporarily until your pet uses the ability. To do so quickly, I suggest using a macro. Do note that macros cannot go onto the pet actionbar, so your will need to find room on your own actionbar. The macro would read as follows, with Nether Shock merely being used for the sake of example:#showtooltip
/petautocasttoggle Nether Shock
Pet Abilities - The Autocast List:
Not all pet abilities should be left on autocast all the time. Here's an overview of when each pet ability should be on autocast, if ever:
Note: Tenacity talents are marked with a T, and the same goes for Ferocity talents and Cunning talents being marked with a F and C respectively.
- Keep on autocast. Not only does it give you
procs, it's the only pet ability (aside from
, and
Froststorm Breath
) that uses Focus to do direct damage.
- Turn off when someone is tanking. If you don't need your pet to have threat, it's a wasted GCD (see above sections).
- Keep off autocast, and save it for occasions when you want to stack your buffs or otherwise amplify burst damage. This is your Ferocity pet's ace in the hole, so use it wisely and make it count.
- Keep it off autocast, and pop it when you can make the most of the Focus boost. This is analogous to CotW in that it is the major cooldown ability for the talent tree it comes from. So, as said above, make this count!
- Since it builds extra threat for the damage it does, and doesn't convert focus to damage as effectively as your pet's Basic Ability, I advise leaving this off autocast unless your pet is actually tanking.
- It's expensive to cast, but gets your pet into combat faster. Put it on autocast if you want your pet to be able to use it, since it costs your pet so much Focus.
- Costs a bit more than Dash/Dive, has a somewhat limited range (being much shorter than your maximum range), but is quite useful in its own right. Ferocity pets are probably best off talenting into this ability only if said pet is going to be used for PvP, although using this in lieu of Dash/Dive for PvE is certainly viable.
Since this also has a high focus cost, avoid talenting for both this and Dash/Dive (which is possible for Ferocity pets) as your pet will exhaust a lot of focus by first casting Dive/Dash followed by Charge/Swoop when within range. Pick one or the other; not both. Other than that, go ahead and leave this on auotcast.
- This autocasts at 50% health, is uninterrupted by damage (yet susceptible to spell interrupts), and immune to pushbacks. Currently there is a glitch where, upon summoning, dismounting or zoning with your pet out, your pet briefly drops to its base health level before stamina is factored. This is confirmed to trigger LYW's autocast, so be careful. For the time being, I'll advise keeping this off autocast or even respeccing your pet until this issue get fixed.
- Keep on autocast; no reason to turn them off, as using them every chance your pet gets should yield optimal DPS.
- Useful ability for soloing or PvP. If left on autocast, your pet will use this the instant it gets affected by a dispellable snare effect. Another option for use is as a panic button to keep your pet alive, thanks to the damage mitigation buff it provides upon use.
Keep on autocast, unless you plan on using it as a tanking ability.
Roar of Sacrifice
- Both can be left on autocast, but you'll have to manually use them in most situations. Intervene's autocast may be broken. I will need to do some more testing to determine when autocast is triggered.
- This has somewhat of a long CD, so use it wisely. Keep it off autocast, as your pet will otherwise use it indiscriminately and waste the CD. The ability works just like any other taunt; it raises your pet's threat against the target to be equal with whoever is currently at the top of the aggro table, and forces the target to attack your pet for the duration of the short debuff it applies.
- This will autocast when your pet loses a significant portion of its health, apparently. The specifics of what triggers the autocast haven't been nailed down yet. So, I would advise using this every CD if your pet is tanking, as well as when your pet gets focused by a boss or player in PvE or PvP, respectively. Cower's autocast could easily be altered again in the near future; it's a balancing act between the needs of pet tanking, and the need for pets to not be slowed significantly when running away in PvE or PvP.
Pet Abilities - No Autocast:
Below are pet abilities that either have no autocast function, or the autocast function is currently broken:
Last Stand
- A Tenacity ability that should not be forgotten. It's similar to a
Battlemaster's trinket
; you use it to boost your pet's health temporarily. This allows more time for healing and damage reduction CDs to save the day, which can be a huge difference with pet healing being centered around a single HoT.
Heart of the Phoenix
- A Ferocity talent that finds use in PvP. Hunters can battle-rez our pets with Revive Pet already. However, it forces us to spend a good ten seconds casting our spell, is vulnerable to pushbacks when unglyphed, and your revived pet can be easily one-shotted before Mend Pet has time to work its magic. HotP instantly revives your pet with full health. The CD is reinforced with an 8 minute
that persists through death, so no use in going to a BG with 5 identical Ferocity pets. Make the most out of this when you do use it; you may be able to catch someone off-guard.
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Pet Stable or Raid Toolbox? - A guide to which pets cover which raid buffs & debuffs:
Any pets or classes that have a
indicates that they aren't the best choice or shouldn't be expected to cover this buff/debuff. Classes in
signifies that while the class/spec can provide this buff/debuff, it limits what other buffs or debuffs that player can apply.
if no
(prot) warrior
, and
if no
feral druid
fury warrior
elemental shaman
, and
subtle rogue
wind serpent
if no
unholy knight
assassin rogue
, and
, or
if no
feral druid
arms warrior
subtle rogue
spirit beast
if no
death knight
if no
combat rogue
arms warrior
frost knight
BM Only:
if no
(destro) warlock
, and
shale spider
if no
core hound
if no
You can find
a thread
with spreadsheets and even an addon based off of them over on
the Petopia forums
All Other Pet Special & Exotic Abilities
Shell Shield
) &
Harden Carapace
) - This makes turtles and beetles excellent tanks when heavy damage mitigation is needed when soloing. The ability works just like
, except a better version. I prefer to use it separately from Cower, since more damage will be mitigated.
Keep it on autocast. Your turtle/beetle will autocast this when it reaches 50% health. However, I like to keep it handy for pre-emptive use, if need be.
Ankle Crack
) - Best slow available to us (except for
Concussive Shot
, but that eats up our GCDs). I'd suggest maybe talenting for
Boar's Speed
to keep your pet's target from escaping.
Keep this on autocast for maximum uptime.
Frost Breath
) - A second less in duration than Ankle Crack, but has a nice range. Given the PvP benefits of having a Cunning pet, I'd tentatively recommend that BM hunters use chimaeras over crocolisks for their kiting pet. That said, both pets are quite viable for PvP.
Keep this on autocast for maximum uptime.
Warp Time
Warp Stalker
) - The tooltip is a bit ambiguous; this is a single-target ability with a 25 yard range that acts just like the above two pet abilities. While this particular ability has a 6 second duration like Ankle Crack, the much longer CD gives this ability the lowest uptime of the three. Given that the range on Time Warp (the only benefit over Ankle Crack) is less than that of Frost Breath, I would advise BM hunters to take a chimaera instead of a warp stalker. In my opinion, warp stalkers don't make for good PvP pets if you can take a croc or chimaera instead.
) - Mainly a PvP ability, with utility against any class save the occasional
Bladestorming warrior
dispersed shadowpriest
frost knight
, or
wrathful beast
. However, this will trigger diminishing returns for all subsequent stuns applied to the target.
Keep this off autocast, and manually cast it at crucial times to interrupt heals, counter damage bursts, and prevent defensive CDs from being used.
) - Save as Sting, except with a longer range but a longer CD as well. I'd suggest taking a wasp over a bat. However, you may not find the longer CD to be too big of a problem and prefer the longer range. Oddly, this ability becomes available to your pet before level 20, but this seems to be a bug as bats don't get
until level 20.
Keep this off autocast, and manually cast it at crucial times to interrupt heals, counter damage bursts, and prevent defensive CDs from being used.
Shale Spider
) - Take the best parts of both Sonic Blast and Sting, buff them as well while you're at it, and you get Web Wrap! CD is as short as Sting, range is longer than Sonic Blast, and has an extra second of duration. I'll go so far as to say that the only reason to use a wasp or bat is if you aren't a Beast Master.
Keep this off autocast, and manually cast it at crucial times to interrupt heals, counter damage bursts, and prevent defensive CDs from being used.
Bird of Prey
) &
) - PvP ability that is potent against rogues. Used correctly, this can wreck a rogue's carefully stacked odds and give you the initiative early on. However, count on a
weapon chain
being used by classes prone to disarms. I even use one as a hunter. But, DKs almost never guard against disarms, and usually use a 2-hander in PvP...
When guarding against rogues, keep this on autocast. Otherwise, save it for disarming other hunters and melee PvPers who somehow manage to get in melee range.
) &
) - Probably the most popular PvP ability (& pets) for hunters in BGs. A rooting ability, which when combined with
(I'm not so keen on
Rank 2
, since 100% uptime on Dash/Dive is a very situational benefit with a high focus demand), can even stop mounted players from fleeing.
Keep it on autocast, although doing so isn't necessary if you are quick to use this when needed.
) &
) - Not as good as Web and Venom Web Spray; hoping for a buff soon. Both abilities are channeled, meaning that your pet is doing nothing for four seconds but holding an enemy in place. So, a terrible choice for BM, but viable for MM/SV. Must be used with
Keep it on autocast, since you want your pet to autocast as soon as its target is within range.
) &
) - Fairly standard tanking debuff that all four tank specs should be applying themselves already. Could have some possible uses in PvP however, possibly in trying to slow down another hunter's DPS and focus regen.
Keep this on autocast, but be careful to disable it when neutral mobs are nearby!
Core Hound
): Great against casters, but a situational benefit. However, the main draw to picking a Core Hound is going to be
Ancient Hysteria
(unless you're in arena), so Lava Breath is more of a bonus than a deciding factor in pet choice.
Keep this on autocast.
): Useful for instance groups where all buffs and debuffs are already covered, but next to useless in PvP. This is rather unique for a hunter pet ability. Spore Cloud is an AoE debuff that is dropped on the ground. Hence, enemies that are standing in the area where the debuff was dropped will be affected, but once they step outside of the debuff zone, they are no longer affected. Hence, this ability is limited in use to PvE, since while players can simply walk out of the debuff zone, AIs won't bother moving so long as their target is in attack range.
Micromanaging will yield best results, but the CD is so short that it probably isn't worth the hassle. Just be careful around neutral mobs.
Nether Ray
) &
) - Spell interrupts with short spell lockouts to boot. Gorillas are quite effective for soloing certain bosses, both Nether Rays and Moths are suitable for PvE, and all three families are decent choices for PvP.
Keep Nether Shock off CD, and use it to interrupt key casts. However, if you keep Pummel or Serenity Dust on autocast, your pet will actually be smart enough to only autocast the ability when its target is actually casting.
) - This works just like
; damage will break the effect. The cast time on this ability means that your monkey has to be stationary to cast, and that there will be a delay, making this inferior to Scatter Shot. Frankly, this isn't very useful.
Keep this off autocast, and manually use when needed.
Monstrous Bite
) - Yes, it does the exact same thing as
. However, the advantages are that you don't have to use that GCD and Focus on putting up the debuff, and more importantly, that it can't be dispelled.
Keep this on autocast.
Burrow Attack
) - A powerful channeled AoE attack. However, your pet's threat is 'hidden' when using this ability, since your pet is out of sight and unable to be attacked (or is supposed to be, at any rate). So, as far as NPCs are concerned, your pet ceases to exist for the duration of the attack. The upshot is that this is really only useful when someone else is tanking, or you're willing to stand right on top of your burrowing worm with Deterrence active.
Froststorm Breath
) - A weaker channeled AoE attack, with a high Focus cost but no CD. To be clear, Burrow Attack is much stronger in terms of AoE DPS. Froststorm Breath
be interrupted by
Kill Command
. Unlike Burrow Attack, the area of effect appears to be a frontal cone (won't do anything to attackers behind the chimaera). This ability is relatively spammable since the chimaera will regen most of the focus by the time it finishes channeling the previous attack (I run with
, which is standard for Beast Masters). Worth noting is that Froststorm Breath can be cast when out of combat and/or the chimaera has no target, and that your chimaera can move while channeling the ability. Hence, you can use Froststorm Breath to flush a rogue out in PvP.
) &
Bloody Screech
Carrion Bird
) - Every single tanking class/spec has a variation of this ability. This makes our bears a rather balanced tanking pet, with extra damage mitigation and AoE threat. Plus, our pet bears inherited their Demoralizing Roar animation from bear druids, making them rather lively pets in combat. As for Carrion Birds, there really isn't much of a use for this at all given that they are Ferocity pets. It could possibly be useful in PvP, yet other pet classes bring far more useful special abilities if you ask me.
Keep this on autocast with a bear to maximize threat output.
Spirit Mend
Spirit Beast
) - Once again, Spirit Beasts get a nice ability that at the same time is anything but game-breaking. If left on autocast, the pet AI will autocast this on you, itself, or any party member that drops below 50% health. However, the bug regarding the delay in stamina scaling kicking in as mentioned for LYW in the above section will also trigger this to autocast on your pet.
Feel free to put it on autocast before entering combat, but taking it off autocast before mounting, dismissing or zoning into an area is advisable so as to prevent erroneous autocasts throwing the ability on CD.
Bird of Prey
), &
): These are Blizzard's idea of a 'fun' ability. Play has the fox do the Ghost wolf /dance animation. As of 4.0.3a release, there seems to be a bug where if your fox is Playing when ordered to attack, it attacks like normal but keeps doing the dance animation. Rest has the bear lie down, with Z's drifting lazily above his/her head like a
Lazy Peon
. Trick will cause the Bird of Prey to do a quick somersault/loop through the air. However, only seagulls, eagles, and hawks have the animation (since they're based off the druid flightform); owls and parrots sadly cannot perform a Trick.
Of all these abilities, Rest is the only one that is actually useful, as it removes the need for low-level players to feed their pet bear.
) &
Spirit Walk
Spirit Beast
) - These are also Bonus abilities, but seem to fit into a unique category all their own in my opinion. The attack bonus is nice, but having your pet attack while stealthed causes an annoying delay in reaching your pet's target. Also helpful (pre-85, at least) is that your pet will have a much diminished aggro radius, meaning that you can try to sneak past hostiles without having to dismiss your pet. A final note; this ability is available to your pet before level 20, which is rather uncommon.
Keep it off autocast, and manually use it when you want. Alternatively, talent for
Boar's Speed
, and keep it on autocast.
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Pet Management Tips & Tricks
Because I thought you wanted more after that first essay!
Well, enough of the lists. I'm sure they're gotten monotonous for you; it sure has for me! I'll go back to basics; how to actually manage your pet. I'll go over three main categories:
PvE DPS
, and
PvE (DPS):
Here are my recommended pet specs for DPS (no clue why non-BM hunters would bring a Tenacity pet to a raid, though).
Ferocity spec
BM version
alt. BM version
Cunning spec
BM version
Tenacity spec
BM version
Below are tips & tricks for managing your pet when in PvE content.
First thing you do upon entering a dungeon party or raid group is turn Growl off. Next, double-check that Growl is off. Thou must avoid committing
the cardinal sin
. Now, turn Call of the Wild (CotW) off if your pet is Ferocity, or Roar of Recovery (RoR) if Cunning. Next, make sure you have Growl and CotW/RoR on your pet's actionbar. Make sure your pet is on Follow and Defensive. You are now good to go!
Your pet should be attacking whenever you're attacking, for the most part. Make sure Omen or whatever you're using to manage your threat (you
have a threat addon, right?) is alerting you of pet aggro when you're in a group. If that alarm goes off, hit Mend Pet (Cower should autocast at this point) so that your pet doesn't die. If your healer gets aggro and your tank doesn't taunt, one of your options (other than
Distracting Shot
) is to send your pet while using Cower and Growl.
Occasionally, you'll reach a ledge where you need to jump off. Blizzard has improved our pets' AI somewhat in this regard. Sometimes, such as in Sunken Temple, your pet will actually leap with you. Other times, such as in Azjol-Nerub, the pet will stay put and despawn before you reach the bottom. However, sometimes your pet will follow you by taking the long way down, often bringing unwelcome guests to your party. Notable places are in the Nexus and Ahn'Kahat. In these situations, simply
Dismiss Pet
"Wowhead: Sometimes there is fire. You need to not be in it."
Not only is this my favorite Wowhead title bar, it's very true and also applies to your pet. Whenever Deadly Boss Mods tells me to run away ("Run away, little girl; run away!"), I hit Passive on my pet's actionbar to save it unless I know that
will mitigate the damage.
Finally, I've created a tentative list of useful pets to bring when using the random dungeon finder:
Beast Masters:
Core Hound
Wind Serpent
Shale Spider
Spirit Beast/Cat
is more valuable than
, you are also far more likely to find yourself in a group with the former debuff covered. Half of the tanking specs not only can but almost certainly will be applying said armor debuff anyways, as it is linked to a key threat generator for warriors and a key pulling ability for druids.
Soloing is basically all PvE content you are intended to do without a group. Soloing for BM hunters is your pet tanking, you healing, with the DPS split between the two of you. Soloing for non-BM hunters is kiting, which I won't cover. So, I'll assume that you are BM in this section for simplicity's sake.
To start, you have a toolbox for making your pet into a tank. There are threat abilities such as
; defensive abilities such as
Last Stand
; protective abilities such as
Roar of Sacrifice
; and finally there's
Mend Pet
. If you expect a lot of damage to be taken by your pet, put up Mend Pet early. The spell relies upon preemption to be its most effective. I use a macro to prevent clipping the HoT (acronym for
heal over time
/cast Mend Pet
/castsequence reset=10 Mend Pet, null
It gives your Mend Pet an artificial CD, which you can override with a modifier such as Shift. Do not underestimate Last Stand; it is capable of tiding your pet through a lot of things. Cower should be used every GCD by your pet when it has aggro.
Your pet's threat generation is sometimes an issue. Don't forget to use Intimidation to its fullest if you have it. Thunderstomp is great for AoE threat generation, but don't lean too heavily on it; attack your pet's target at all times if you can help it. Growl is a given; leave it on autocast for soloing. Now, what if you you still pull aggro? In addition to Deterrence, FD, and Freezing Trap, your pet has a few tricks as well. Intervene is a pretty nifty way of focusing your pet on your attacker. Taunt will work on most mobs, but isn't a guarantee with raid bosses. Plus, it's a long CD for a taunt, even after Longevity, so use it wisely. If your pet is busy but isn't taking a truckload of damage, it can give you RoS if you've actually talented your pet into that.
There is soloing, and then there is extreme soloing. A general definition of extreme soloing is pushing the limits of what group content can be tackled alone (someone even managed to solo Vortex Pinnacle with only one boss and two mobs skipped - on heroic). For extreme soloing, you need to pull out all the stops. I find it to be a thoroughly enjoyable the challenge. Here's some resources (I'm afraid they are a little dated, as they were written during WotLK) to help you if you believe that
Suggested Players: 3
really means your hunter, your pet, and your ego:
Eidotrope @ OutDPS
Very well-written introduction to extreme soloing.
Scattered Shots
For you Frostheim fans out there. The video is more impressive than the guide, however. It's more conceptual than in-depth.
OK, fine, so we can't tame druids - yet. But, we can make do with taming their wild cousins, and using them to our advantage. One thing I love about PvP is that almost any pet can be surprisingly useful in one way or another.
First off, I want to go over a few lesser-used pet abilities that you shouldn't overlook or forget:
: I like to use this right after popping BW. The only thing worse than a big red pet is a big red pet that just stunned you!
Master's Call
: Please note,
this does not replace a
PvP Trinket
However, don't neglect this either. It's very useful for throwing a monkey wrench in someone's plan when they try to force your trinket on CD. A good PvPer will notice that you used this instead, but that's another of their abilities put on CD, which is the whole point. Also a good idea to use this on friendly flag carriers when they get snared.
Roar of Sacrifice
: Being crit-immune is nice. However, this is a rather situational pet talent to take for a class that stays out of melee at all costs in PvP. A Tenacity pet should have this ability by default, being a prereq for Wild Hunt. So, in that case, you might as well make use of it. However, this ability is more optional for Cunning pets; I leave the choice up to you. This ability is nice overall, but I caution against overconfidence. RoS or not, a brush with melee will still be a brush with death. If you do get this ability for your pet, be sure to use it on healers or flag carriers in trouble.
Pet selection is wide open for PvP. Your pet can disarm (Bird of Prey/Scorpid), root (Spider/Silithid, Crab/Dog), stun (Wasp, Bat), interrupt casting (Nether Ray/Moth/Gorilla), slow (Crocolisk, Chimaera), slow casting speed (Sporebat/Core Hound), or even heal (Spirit Beast). Whichever ability you want your pet to have is a playstyle choice. Some abilities, such as a Core Hound's Lava Breath, are fairly straightforward. I'll go over a few tricks for your pet in PvP.
To begin, rogues (and their
). Anyone who's ever guarded a node in Arathi Basin knows what I'm getting at. We are the best class at detecting them, but they also are arguably the best at getting into our melee range and staying there. So, we'll start with
-camping. This is you at your most vulnerable. Throw down the flare, make sure
Track Hidden
is active (no excuse to turn it off post-4.0.1), put your pet on aggressive, and don't let the flare die on you! The key that many overlook is the Aggressive pet. You won't get enough notice for your human reflexes of an impending ambush, even with Flare and Track Hidden, but your pet's AI sure can! Nothing ruins your day like a blown sneak attack. If you have a Bird of Prey or Scorpid, then hopefully the rogue is disarmed before it can stun you. Expect a weapon chain if the rogue is worth anything, however. Another possibility is to have your pet stun the rogue first with Sonic Blast or Sting! Worth noting is that unlike a disarm, a stun is also assured to work against a druid kitty. Either way, with the right pet you can render a rogue helpless for 2-3 seconds, enough time for you to make a getaway and make the rogue regret picking a fight with you. If it's a druid kitty, buy your extra time at first with
, giving you time to lay traps and begin kiting.
Interrupting spellcasting is an interesting ability. The best use I see is in interrupting a heal with a noticeable casting time, enough for you to react. Interrupting a heal is a golden opportunity. Not only will no more healing be occurring for a couple seconds, but in the case of a paladin and to a lesser extent a priest, their defensive abilities are also interrupted. I can see this being a linchpin for a skilled arena team.
I am open to more suggestions on my PvP section, since I only PvP casually. There are simply too many possibilities!
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Mini-Guide on Extreme Soloing & Pet Tanking:
...Shut up, Xzibit.
Mini-Table of Contents:
Pet choices
Talent specs
Generic strategies
There are different ways to go about extreme soloing, and each hunter spec has its uses in this regard. You can chain-trap mobs as SV (less effective now, since double trapping has been made impossible), heal yourself through unavoidable damage as MM, or make your pet into as good of a tank as you can as BM. I will focus on the pet tanking method in this mini-guide, as it pertains to my overall topic. Besides, I am more familiar with it.
Gear for extreme soloing really depends on the challenges of the content you want to tackle. That said, typical soloing gear sets will be composed mostly of raid gear. If you want to know where to start on that, I refer you to
Daefaroth's excellent gearing guide
. So, the following gear suggestions are replacements for your regular raid gear.
~The default meta gem is
Agile Shadowspirit Diamond
for hunters. However, socketing
Invigorating Earthsiege Diamond
on a helm that you don't plan on using for raiding is a good idea for fights where you need to periodically heal yourself. It won't be anywhere near enough healing on its own when needed, but the extra healing on top of
First Aid
Spirit Mend
Chimaera Shot
is the benefit that I see. It's a matter of choice.
~There's an old tier of raiding gear, the Tier 5
Rift Stalker Armor
, which has curiously proven to be useful long after it became irrelevant, thanks to the
2-piece set bonus
it has. I recommend obtaining the
Void Reaver
, and supplementing that with one of the following:
Kael'thas Sunstrider
Lady Vashj
Fathom-Lord Karathress
Pet choice is an important factor for pet tanking (need I explain why?). A general rule of thumb would be to stick with
pets. However, I don't consider that to be a steadfast rule, as I myself use a
Spirit Beast
, and
for certain situations when soloing.
So, here's a rundown of what pet classes I find useful for soloing (due to their special abilities and exotic abilities):
: With
serving as a quick and easy way to tag everything in your bear's melee range as well as providing steady damage mitigation, I consider bears to be excellent pet tanks. I use my bear as a general-purpose tank; if it's not a challenging boss and I don't need a specific special ability to get the job done, then I send in my bear.
: Many will argue that these are the best pet tanks, hands-down.
Shell Shield
Harden Carapace
can tide your pet through damage spikes, or give a chance for Mend Pet to catch up on healing by increasing the pet's net gain in health over time (healing received minus damage taken). I use my turtle as my default tank for boss fights; better safe than sorry.
: Since the nerf to
Mortal Strike
type debuffs (they used to reduce all healing received by the target by 50%), I feel that gorillas have become more important for extreme soloing.
is very useful for stopping interruptable spells in boss fights that were considered mandatory to interrupt back when said boss fights were current content. In most cases, such spells are powerful flash heals. Something else that's particularly useful about Pummel is that your gorilla won't autocast it until the ape's target begins casting a spell. Hence, your gorilla will be on the dime with interrupts if you leave the ability on autocast. I almost always bring my gorilla when soloing.
Spirit Beast
: This is a bit of an unusual choice, and not exactly easy to obtain. However,
Spirit Mend
is incredibly useful for healing yourself mid-fight. The main restriction with using a non-Tenacity pet is that fighting more than one target is out of the question without
Shale Spider
: These jumbles of rocks and stone are the up-and-coming stars of pet tanking. Both
have their uses for pet tanking, with the former being a potent raid buff and the latter being the best stun that hunters can use. While bosses are immune to stuns as a rule, I expect Web Wrap to have a lot of potential in managing trash packs with use in tagging new adds or stopping a spellcast being done by a mob out of the shale spider's melee range.
: Ever since
Burrow Attack
was changed so as to have aggro 'hidden' when used (your worm drops off aggro tables while using Burrow Attack but doesn't get rid of that aggro completely, just like a Night Elf using
), worms have by and large been stabled by their disappointed masters. However, I argue that they are still very much useful (so long as you don't bother using Burrow Attack). This is because
is no only handy for tagging mobs early, but disproportionately affects your worm's DPS and threat generation relative to your own. So, I consider them to be the highest single-target threat generators among pet tanks (when specced properly, of course).
: The only reason I use a chimaera when soloing is because they can function as flying trash incinerators thanks to their
Froststorm Breath
. I only use them on non-elite trash packs that were always meant to be AoE fodder. Very nice to bring along if you expect to encounter said AoE fodder.
: Their
ability will significantly reduce the damage done by NPCs that rely heavily on their weapon(s). So, if you were to encounter a boss that is dealing too much weapon-based damage during a burst phase that
can't dispel and a turtle or beetle has proven to be unable to survive the fight, then a scorpid may just be your answer. Such situations may in fact be encountered as tBC raids and WotLK heroics become the new challenges for extreme soloing.
Warp Stalker
: These pets would merely be a choice of convenience thanks to their slows that they regularly apply. The benefit of said slows would be in helping your pet build up or regain aggro on a moving mob. The benefit of
Ankle Crack
would be a higher uptime, while the benefit of
Warp Time
would be that the ability doesn't require your pet to be in melee range.
Specs for yourself and your pets have got to be one of the biggest factors in your success with soloing. For your own spec, I'd recommend the following
Beast Mastery
spec, and point out these possible
specs as well. I feel that
is underrated for soloing, since it directly or indirectly boosts the number of procs of talents such as
Cobra Strikes
as well as increasing T5 2pc healing. Also,
Kindred Spirits
is the rather underwhelming alternative for that talent point.
As for your pet, you have a number of options (all specs assume that you are using the above Beast Mastery spec yourself). For some ideas as to what specs I use,
check my stables
. First, the non-Tenacity pet soloing specs:
Cunning (threat)
Cunning (survivability)
, and
(Chimaeras get their own, special spec since they will hardly be using anything but Froststorm Breath, and can't afford to waste focus on
). Now, for Tenacity specs, I consider the following talents to be essentials:
Blood of the Rhino
, and
Last Stand
The following specs are different spec ideas that I use in different capacities:
Max damage reduction
Max threat generation
Max AoE threat generation
'Panic mode'
(dealing with spawning adds, threat-clearing mechanics; stuff that tanks hate)
Generic strategies for soloing boss fights are variations on how the boss fights would have been done back when said boss fights were current content. In some ways, soloing these fights now is simpler; your pet can safely ignore most AoE damage thanks to
, and in old enough content will be able to absorb damage from a boss fight that had previously required two separate tanks. However, soloing bosses designed for parties or raids has its own set of unique challenges that sometimes will even prove to be insurmountable. In fact,
Razorgore the Untamed
(first boss of
Blackwing Lair
) is utterly impossible to solo, and I don't forsee
Kael'thas Sunstrider
Tempest Keep
becoming a soloable fight anytime soon. But, there are some ways to get around seemingly impossible fights, and I'll go over some generic strategies that will cover most boss fights.
Your pet has tools to survive a regular tank 'n spank fight almost indefinitely as long as the incoming DPS isn't too high (nobody's running out of mana on our end of the fight!). However, the same is hardly true for you when it comes to raidwide damage.
One option is to actively heal yourself through passive raidwide damage. This can either be done with a
Spirit Beast
Spirit Mend
if your pet only needs to hold aggro on one NPC, or by switching into the aforementioned Marksmanship spec and using
if your pet is handling his or her end of the boss fight without a problem. The former is a more powerful heal but has a longer cooldown, and thus is better suited for healing through occasional but hard-hitting raid damage; the latter being better for consistent and steady healing. Self-healing can of course be supplemented by
Dense Embersilk Bandage
s whenever you have an eight second window of no DoTs or incoming damage/interrupts.
If you can't heal through the damage, another option would be to get out of range of whatever is killing you. First, you need to look up what the max range of the particular ability is here on Wowhead. If the range is 100 yards (the range at which your pet will despawn), then forget about it. If the range is 40 yards, then you merely need to get out of range of all your shots in order to keep yourself safe, such as on
. The fight will be very protracted, but you will still be able to use
Mend Pet
Kill Command
Bestial Wrath
. On some fights, you may opt to only run out of combat to bandage yourself every time
Recently Bandaged
fades, such as on the super-lengthy
Sulfuron Harbinger
fight (you have to force all four
Flamewaker Priest
s to run out of mana so that they will stop casting
Dark Mending
Back to Table of Contents
Post by
...people get Lick Your Wounds? o_O
Post by
I'm taking a thorough approach here. Sure, I could have left out LYW, but I've already gone to the effort of creating the link...
Post by
But, like, people get LYW? o_O
Post by
Hey, we've all heard stories of
huntards getting Spell Power in the hopes of buffing Arcane Shot...
Rundowns of the pet talent trees can already be
found in the stickies
. It's missing the Tenacity talent tree, though. Maybe I can think of something to help address this...
Post by
Hey, we've all heard stories of
huntards getting Spell Power in the hopes of buffing Arcane Shot...
Rundowns of the pet talent trees can already be
found in the stickies
. It's missing the Tenacity talent tree, though. Maybe I can think of something to help address this...
I've actually seen a hunter wearing mail elemental gear AND gemmed spell power in SV spec, I assume to try and get extra damage out of explosive shot?
I have a question about the focus dump, with Go For The Throat talent, my pet almost never falls below half focus, so will my wolf always be using the focus dump? Althought I can't find another ability that uses focus apart from furious howl and is an attack?
Post by
This can
be accomplished by a few lines in one or more of your macros:
Found a typo for ya :), but great start so far. We really need something about the pets, given they are a major part of being a Hunter.
Post by
and having a good time with your pet.
Thats sounds a little awkward, might want to word that differently. All in all nice guide, but its more about pet skills than micro management really...
Post by
Hey, we've all heard stories of
huntards getting Spell Power in the hopes of buffing Arcane Shot...
Hey, now, that worked in Vanilla, and I was one of them.
750 spellpower. In Vanilla. 380-damage Serpent Sting ticks, $%^&*es. :P
Edit, for clarity: I had an actual gearset, too (I was my guild's 8/8 Dragonstalker slave), but I used the spellpower one for gimmick stuff like Chromaggus.
Post by
What happened to Scorpid Sting?
I know it was nerfed, but i still use scorpid for pvp...shame on you Cialbi...
Post by
and having a good time with your pet.
Thats sounds a little awkward, might want to word that differently. All in all nice guide, but its more about pet skills than micro management really...
Thanks for the feedback. I've still got room, and plenty of time this weekend, so I'll see about expanding this!
What happened to Scorpid Sting?
I know it was nerfed, but i still use scorpid for pvp...shame on you Cialbi...
Totally got overlooked there. The editing window gets a little hectic with a long list like that one.
Post by
Some of the answers from my "Attack This not That" question would work well here since it was a micro-management question.
I really like this!
Post by
Ooh, good idea! I'll create a new section after dinner.
Post by
and having a good time with your pet.
Thats sounds a little awkward, might want to word that differently. All in all nice guide, but its more about pet skills than micro management really...
Well, I've added on an entire section in an attempt to address the lack of focus (I also changed the title <.<). However, I can't find your quote for the life of me. Can you give some more context so's I can find it and see what I can do?
Post by
Ctrl+f "Good time". Warp Stalker section.
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text:
Honors Track
Outstanding International Studies majors who are interested in departmental honors should arrange a meeting with the Director of Undergraduate Studies, Olga Kalentzidou (okalentzindiana.edu) and submit an Honors Authorization Form to the International Studies advisor, Emily Williams (elwillindiana.edu) no later than the second semester of the junior year.
Completion of the Honors Track necessitates:
- Completion of 15 credit hours in the major prior to application
- GPA of at least 3.5 in the major and 3.3 overall
- Completion of INTL-I315
- Submission of Application and Eligibility Form
- Students should enroll in INTL-I406
- Students are encouraged to enroll in one credit hour in X-390 prior to taking I-406
- Identification of an Honors Thesis Director(the Thesis Director must be an International Studies core faculty member)
- Establishment of an Honors Committee comprised of the International Studies Director of Undergraduate Studies, the Thesis Director and one faculty member, i.e. third Reader, of the student's choice
- Submission of an honors thesis of approximately 50 pages
- Defense before an International Studies honors committee
- Final grade of A– or higher
- The grade for the thesis will be given jointly by the Thesis Director and the International Studies Director of Undergraduate Studies in consultation with the I-406 instructor.
Additional Resources:


text:
Bristol's citizens police academy set for March
Bristol residents who would like to experience what it's like to be a police officer in town are invited to enroll in the Bristol police department's citizen's police academy. The 10 week program is designed to provide citizens of Bristol a better understanding of the mission and operations of the Bristol police department.
Each week, participants will experience the various operations that take place in local law enforcement, including the department structure, patrol procedures, dispatch operations, narcotics, search warrants, crime scene investigation, use of force, domestic violence, traffic enforcement, D.U.I. investigation, duties of the school resource officer, juvenile crime and the court system.
Classes will meet on Tuesdays from 7 p.m. to 9 p.m. for 10 weeks, beginning on March 5. Applications must be returned to the Bristol Police Department by Friday, 1 March 2013. Personal identification will be requested upon return of application. Those who attend 80 percent of the scheduled sessions will receive a certificate of completion.


text:
Barbara Desoer, President, Bank of America Home Loans
The Future of the Housing Market
Barbara Desoer, President, Bank of America Home Loans
Jed Kolko, Ph.D., Policy Fellow, Public Policy Institute of California – Moderator
Bank of America's purchase of mortgage giant Countrywide three years ago came at the height of the housing crisis. Since that time, Bank of America has spent billions of dollars to clean up legacy issues including a recent announcement to pay $8.5 billion to resolve nearly all of the Countrywide-issued first lien residential mortgage-backed securitization repurchase exposure - the largest settlement in the banking industry to date. Desoer will discuss the future of the housing market: the various reforms in play, the state of lending, foreclosure trends and housing recovery metrics. With Bank of America being the largest U.S. bank by assets and the nation's second largest lender, originating one out of every five home loans, Desoer is uniquely positioned to provide insight into the housing industry. She has been with Bank of America since 1977 and, in 2010, was named one of the "50 Most Powerful Women in Business" by Fortune magazine and one of the "25 Most Powerful Women in Banking" by U.S. Banker.
Location: SF Club Office
Time: 5:15 p.m. networking reception, 6 p.m. program
Cost: $20 standard, $12 members, $7 students


text:
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text:
The mystery of the SS Koombana
15/03/2012 , 5:38 PM by Gemma Snowdon
It's approaching the 100th anniversary of the disappearance of the SS Koombana.
The ship disappeared during a cyclone in 1912 and the wreck has never been found, spooky since there's a cyclone in the same area almost 100 years to the day!
The ship was said to have a cursed pearl on-board, a story that Annie Boyd knows a bit about.
She's writing a book, which will be released next year, called Koombana Days: a history of the North West...
Graham de vahl Davis is a descendent of someone on the ship, he shared the story with ABC North west...
You can follow this conversation by subscribing to the comment feed for this post.
Looking forward to your book. My Great Uncle, Walter Clifford Thornton went down on this ship and we were listening to the story on Sunday all over with Macca yesterday so really interesting.
Posted by: Ron Coward | 19/03/2012 at 10:46 AM
My grandfather (my mother's father), Thomas O'Loughlin, was lost on the Koombana. He was a member of the crew and worked in the engine room.
My mother, the youngest of five girls, was thirteen months old at the time. His wages were calculated to the time it was thought that the ship was lost, it was the only money that my grandmother received from ANL. She then had to go to work to support and raise her five daughters.
Lou Cassar
Posted by: Lou Cassar | 02/04/2012 at 09:53 PM
My grandmother told me about the Koombana when I was a young boy.
Her father, my great grandfather, was given captaincy of the ship on that fateful voyage. It was told to me that as he was about to sign the articles enabling him to take charge of the ship, the nib fell from the pen. This happened three times. He, being a superstitious sailor, refused to accept the post. My grandmother was to sail with him as a serving girl in the crew.
Posted by: John Parkes | 07/04/2012 at 09:38 PM
My cousin Anistasia Critchley was lost on the Koombana, a fact I had not been aware of untill I started the journey of our family tree.
Posted by: Terry Newman | 27/04/2012 at 09:04 AM
The comments to this entry are closed.


text:
As of this week, he'll be doing it again. Older - but not wiser - this is his weblog of the 2005 Tour of Scotland.
So eyes down, here we go. Again. It seems like only yesterday.
No, actually, it's two years since the last round of pattering politicians seeking advancement sent me off round Scotland to look for an election campaign.
Along the way a radio car died. A small and extremely dirty conveyance christened Plan B took its place. And we found an election, without - proud boast - having to speak to a single candidate.
What it proved for me is that there's plenty political interest out there in a Scottish community that's as divergent as it's ever been. It's just that the politics the people are interested in are not necessarily the politics the politicians are offering.
So will the people of Scotland speak out this time round? Well, I'm about to find out. I've high hopes of the radio car turning up this time and if it doesn't, Plan B is a newer and marginally cleaner car. Though it may not be by campaign's end, if we have 2,000 miles to go, as we did last time.
And this time it's different. This time it's Westminster not Holyrood. This time it's not about big electoral Issues, like health and education and crime, because these are devolved. In Scotland, this means they're decided by Holyrood and not Westminster.
'Surprises along way'
Instead we'll only hear about what's reserved to the London parliament - issues like defence, immigration and the economy. We won't be hearing about hospitals, schools and electronic tags, therefore. Oh really? Read any papers lately?
The politicians may have designed devolution. They may know the theory. But that doesn't mean they'll stick to the rules over this, or anything else, in the next few weeks. And just to make absolutely certain, the Scottish Parliament will keep on trucking pretty much all the way through this campaign, with MSPs eager to pick up anything their south-of-the-border colleagues miss out on.
Today, though, a BBC Scotland poll looks at some of those big picture issues and what people think about them; 1,000 people in this case who were asked about issues as divergent as Iraq, independence, ID cards and immigration. The results are interesting enough to keep pundits and politicos going for some time to come.
Top of the heap in terms of priorities is more money on health and education. It may be argued that it proves we're still wedded to the welfare state, but it's also not surprising that it remains high on the priority list north of the border. After all it would have been top of the pops as a Scottish electoral issue even at the height of Thatcherism.
More for pensions too. Well it's been an issue throughout the lifetime of this parliament and the electorate is getting older. But keeping immigration down?
In a country with a skills shortage where the Executive wants more immigrants? A country that has a tiny proportion of the British immigration figure?
Message to politicians
Is this dog-whistle politics, kneejerk politics or can the pollsters be wrong? And if the pollsters aren't wrong, what message are the people sending the politicians now?
Interestingly, too, the introduction of ID cards seems to find favour here - they're high on the list of priorities with a vote of more than two-to-one for their introduction.
Independence, on the other hand, is 2.1 points down, at least according to our poll. Even some SNP voters opted against independence, it seems.
The only real poll, we will be told by parties who don't like these figures, is on 5 May. But how much will the results of "unreal" polls like this one influence what they say and do between now and then?
So, here we go. Today I'm rolling down the A9 heading for Glasgow and my own unscientific polling. I'll be examining whether we're looking for more morality - and more religion - with our politics.
The campaign came to a halt on Friday to mark the Pope's funeral. Strangely it then resumed to mark the Royal Wedding.
But, following the death of a Pope credited with a major part in the collapse of Communism, should church leaders have more to say about world leadership? Should the politics of a predominately Presbyterian country more reflect those churches' stance on moral issues?
Or would we just finish up with a hundred and one damnations? Should we be more inclusive of Islam? And is George Bush's America a shining city on a hill - or a dreadful example?
Surprises and scrapes
There will be more questions to ask and be answered over the next few weeks. And watch this space. My progress - such as it is - will keep coming up here.
There will be surprises along the way. There will be scrapes. There may even be a fully functioning radio car. And there will be an election on 5 May.
I'll try to get you there and you can help me - by e-mail to the website with suggestions, tip-offs and even requests to shut up.
Well, maybe not that one.
The BBC may edit your comments and not all emails will be published. Your comments may be published on any BBC media worldwide. Terms & Conditions


text:
I am SO frustrated with myself! Since coming back to skating a month ago (after a LONG absence) I have been relatively pleased with my progress (for an over-weight, out of shape, 56 year old). With about 17 hours on ice, I had all my forward edges come back during Tuesday's session and IT FELT SOOOOO GOOD!!! I actually felt like a skater again and spent the last half of that session doing scallops and 8s on all 4 forward edges and absolutely revelling in it.
Friday night I didn't sleep worth $#^*@#, only a couple of hours. I knew Saturday's skate was going to suffer for lack of sleep and IT DID In 2.5 hours I only got my LF edges back and even those were wobbly - the right leg was absolutely brain dead! I couldn't hold my RF edges to save my life.
There are only a few more weeks left in the regular season, then "spring skate school" (for which I am already registered) and "summer skate school" (still waiting for the application). My goal is to have all my edges back solidly for next fall so I can spend next winter working on my Skills (MITF) and preliminary Freeskate.
I have ice available today (two different places, all day long) and I am REALLY tempted to get out there and PUSH, PUSH, PUSH! But my body says I worked hard yesterday and should "rest" (maybe do balance and stretch exercises, work on the right leg).
Being a "Type A personality" is good in a lot of things but it makes it hard to do what you think is right (rest & exercise) when you're not holding on to your goals (gains - forward edges). Maybe somebody should keep my skates under lock and key? :banging: LOL!
No response required - just expressing my frustrations among those who may understand


text:
Not only did Justin bring Pattie Mallette to the 2012 American Music Awards, but he thanked her in his first victory speech!
Justin Bieber is a total mama's boy, and we love him for it! Fresh off his split from Selena Gomez, the Biebs walked mom Pattie Mallette down the 2012 American Music Awards red carpet Nov. 18. He also thanked Pattie, along with manager Scooter Braun, when he accepted the award for Favorite Pop/Rock Artist — but for obvious reasons, left Selena out of his big speech.
"First of all, I want to say, this is for all the haters who thought that maybe I was here for one or two years — but i feel like I'm gonna be here for a long time," Justin said after his first victory. "Second of all, I want to thank my mom, Scooter Braun for being a mentor and role model … wanna thank my family at home; thank all of my beautiful, beautiful fans; and last thing, I love everybody!"
HollywoodLifers, what did you think of Justin's speech? Do you love that he took his mom as his date? And are you disappointed to see him at the AMAs without Selena? Drop us a comment with your reaction to tonight's Bieber festivities.
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text: Large foam filled locking castors provide a stable, reliable base, while its slightly raised platform lip prevents items from sliding off. Slotted areas allow for accessory brackets and restraining strap attachments, which is a real benefit over other cart designs. It can be hand-pulled or towed, and folds easily for compact storage. The baked-on finish will help your investment last for years.


text:
Grilled Rib Eyes
Michael?s recipe is a perfect party dish for your next backyard cookout!
- Ingredients
- step-by-step directions
Grilled Rib Eyes
- 4 tablespoons Kosher Salt
- 1 tablespoon Granulated Sugar
- 1 tablespoon Toasted and Ground Coriander
- 4 Beef Rib-Eye Steaks, 1 pound each (preferably Dry-Aged USDA Prime)
- Olive Oil
- Crushed Red Pepper Flakes (to taste)
- Combine the salt, sugar and coriander.
- Rub into the Steaks.
- Heat a charcoal or gas grill to medium-high. Drizzle Steaks with Olive Oil.
- Grill the Steaks to the desired doneness, 3 to 5 minutes per side for medium-rare. Remove from the grill and let rest, uncovered, for 10 minutes.
- If desired, drizzle cutting surface with Olive Oil, additional Coriander, Salt, and Crushed Red Pepper Flakes.
- Slice Steaks before serving warm.
- Helpful Tips:
1. Planning ahead and seasoning overnight makes the steak even more juicy and delicious the next day.
2. Bone-in rib eye translates to more flavors in the meat from the inner muscular fat.
3. 1 part sugar in the kosher salt rub gives the steak a nice crust.
4. If the steak flames up once you open it on the grill the simple way to stop that is by just closing the grill top.
Similar categories: Ingredients Beef Steaks Courses & Meals Dinner Beef Techniques BBQ & Grilling
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text:
When I first moved to Humboldt County, I lived out of the back of my car. I had relatives in the area, but they were in a confined space and made it clear that I needed to find my own. I wound up living in a local trailer park until I found a studio apartment for under $400 a month (must have been the last one), owned by none other than the legendary (or notorious depending on your point of view) Floyd and Betty Squires, who turned out to be friendly and cooperative landlords, at least for me.
And so my experience in Humboldt County began. I was by no means destitute, just in need of some help and support to get on my feet and move along. Most of us come to these times of transition, when we have to look to others for assistance. My experience in both social work and ministry is that meeting people with respect along with support is all that a majority of people need or ask for. The rest tend to move along or, in some cases, make the changes necessary to reenter society, so to speak.
When we read about people being chased or bulldozed from their homes because they represent a blight on the community, we generally think of countries such as Brazil, getting ready to host the Summer Olympic Games in 2016, deciding that the poor areas of Rio de Janeiro, called favelas, are a blight. We forget that Humboldt County has a history of doing just this very thing, from the forcible removal of the Native American and Chinese communities to, more recently, the homeless.
In 1990, I was asked to perform a funeral service for two men who were brutally murdered by local vigilantes. The men's names were George Mitchell and Michael Redner. Both were Vietnam veterans, between jobs, who happened to be camping behind the Bayshore Mall at the time of their murder. The incident highlighted the vulnerability of people without housing and helped inspire some in the community to provide more infrastructure to support people like them.
We have been somewhat successful in helping people who find themselves without housing. However, there still is no campground in the Eureka area to support people in transition. Such a campground requires management, as does any public place of gathering. It also requires the will of the people, including government, in order to maintain these services.
So, instead of another mass eviction of homeless people from behind the Bayshore Mall, with no alternative presented to them, how about this: We create a model campground, one that could be duplicated in a rural, environmentally sensitive region such as ours.
A campground like this has been proposed by a program called New Directions. John Shelter, owner and manager of New Directions, has successfully leveraged grants from a number of sources, including the California State Coastal Conservancy. The work of New Directions in helping mitigate the impact of the homeless on the environment, as well as assisting people make the transition into housing, has garnered praise and support from the Eureka City Council, the Trinidad City Council and the Arcata City Council, where John served for many years as manager of the Arcata Service Center. In addition, his efforts on behalf of the homeless have won praise from the Eureka/Arcata/Trinidad Police Departments, along with members of the business community throughout our region.
What has he done to earn this praise? To speak plainly, among other things, he hauls a lot of trash out of the woods, at minimal cost to the rest of us. And in doing so, he gives meaningful work and a sense of purpose and responsibility to men and women who otherwise would be left on the streets, literally, to fend for themselves.
Funding for New Directions from the Coastal Conservancy ran out in January. John Shelter says, "It is no surprise that three months later, the situation behind the mall has gotten out of hand." He went on to say, "These people aren't going anywhere. The idea we can solve the problem of homelessness by shoving people from one place to another is ridiculous. I'm not in support of a permanent campground; I think what we need is a managed, transitional campground built on the model that is already successful throughout California."
John has a model, for those who may be interested, based on the already legal state campground model. I nominate John to run such a program. He has the experience and track record, as well as the uncommon gift for this kind of work. As he puts it, "I don't need any more POLITICS." This is about people, after all.
The Rev. Eric Duff is an Episcopal priest and licensed clinical social worker who writes this column for the Times-Standard. He has a psychotherapy practice in McKinleyville. He can be reached at firstname.lastname@example.com.


text:
More than 500 Northland workers have been seriously injured on the job in the past three years.
EPMU Northland organiser Andrew Bourke said some employers were reluctant to deal with serious health and safety issues.
Common workplace accidents in Northland included falls from a height, while five workers were badly hurt from contact with electricity.
Twenty-five workers were badly hurt in motor vehicle accidents, 15 suffered serious injuries after being hit, struck or bitten by a person and four others were seriously hurt after being deprived of oxygen, or suffocating.
Figures released by the Ministry of Business, Innovation and Employment show nearly one in four injuries was caused by falls, trips or slips.
Mr Bourke said that while some Northland employers take workplace health and safety seriously,- "it's the few that don't who ruined it".
"In Northland, we have the good, the bad and we have the downright ugly."
Guyco Timber Ltd, trading as Northern Pallet & Timber, was fined $50,000 when a worker had his thumb and forefinger amputated by an unguarded saw blade. It was the largest health and safety prosecution case in the region during the three years to August 2012.
Nationwide, 16,468 serious harm workplace accidents have been reported during the past three years.
At least 20 workers have died on the job this year.
A prosecution can result in a fine of up to $500,000 or a two-year prison term if an employer is found guilty of failing to ensure a safe work environment.
Fishing company Sealord was fined $63,400 last week and ordered to pay reparations of $12,500 to a fisherman who fell through a hatch and ruptured his spleen on the Ocean Dawn in October 2011.
The largest penalty imposed during the past three years was on Kiwi Steel NZ, - ordered to pay $237,500 in March 2011 after failing to report that two workers had the skin stripped from their fingers, one worker had part of their finger amputated and another broke his foot when a piece of steel fell on it.
The Employers and Manufacturers Association said many employers took health and safety seriously.
"Employers invest a lot of time and money in their businesses and their staff are the business," occupational health and safety manager Paul Jarvie said.


text:
Liu, Jun M., Chen, Rong and Yao, Qiwei (2010) Nonparametric transfer function models. Journal of Econometrics, 157 (1). pp. 151-164. ISSN 0304-4076
Download (358Kb) | Preview
In this paper a class of nonparametric transfer function models is proposed to model nonlinear relationships between 'input' and 'output' time series. The transfer function is smooth with unknown functional forms, and the noise is assumed to be a stationary autoregressive-moving average (ARMA) process. The nonparametric transfer function is estimated jointly with the ARMA parameters. By modelling the correlation in the noise, the transfer function can be estimated more efficiently. The parsimonious ARMA structure improves the estimation efficiency in finite samples. The asymptotic properties of the estimators are investigated. The finite-sample properties are illustrated through simulations and one empirical example.
|Item Type:
|Official URL:
|Additional Information:
|© 2010 Elsevier B.V.
|Library of Congress subject classification:
|H Social Sciences > HB Economic Theory
Q Science > QA Mathematics
|Journal of Economic Literature Classification System:
|C - Mathematical and Quantitative Methods > C1 - Econometric and Statistical Methods: General > C14 - Semiparametric and Nonparametric Methods
C - Mathematical and Quantitative Methods > C2 - Econometric Methods: Single Equation Models; Single Variables > C22 - Time-Series Models
|Collections > Economists Online
Departments > Statistics
|Date Deposited:
|16 Aug 2010 08:45
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