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|11th week of 2010 patent applcation highlights part 44
|Patent application number
|METHOD FOR SCREENING FOR VITAMIN D RECEPTOR LIGANDS - The present invention relates to a screening method for a compound and includes a step of detecting binding between a vitamin D receptor and CDP. A novel method enabling screening in vitro of a compound having strong bone forming action and low side effects, a compound participating in osteoblast differentiation and selected by the method of screening, a therapeutic agent containing the compound for diseases intervening in the increase in vitamin D-mediated transcriptional activity by a complex of a vitamin D receptor and CDP, and a kit for performing the screening method are provided.
|Methods for Identifying Compounds that Modulate WNT Signaling in Cancer Cells - Provided herein are methods for screening compounds for their ability to modulate Wnt signaling in cancer cells.
|METHOD FOR DETERMINING A TONGUE CANCER - An object is to provide: a method for determining a tongue cancer in which the malignancy of tongue cancer can be objectively and accurately determined; a method for analyzing a tongue cancer tissue specimen; and a kit for analyzing a tongue cancer tissue specimen. There is provided: a method for determining a tongue cancer, comprising measuring mRNA quantity of an integrin family gene and a reference gene in the tongue cancer tissue specimen, and determining the malignancy of the tongue cancer based on a ratio of the mRNA quantity of the integrin family gene/the mRNA quantity of the reference gene; a method for analyzing a tongue cancer tissue specimen, comprising the steps of measuring mRNA quantity of an integrin family gene and a reference gene in the tongue cancer tissue specimen, and correlating a ratio of the mRNA quantity of the integrin family gene/the mRNA quantity of the reference gene with clinical data; and a kit for analyzing a tongue cancer tissue specimen.
|METHODS AND PRODUCTS FOR IN VITRO GENOTYPING - An in vitro method for genotyping genetic variations in an individual, and products for use in the method.
|Methods of PCR-Based Detection of "Ultra Short" Nucleic Acid Sequences - The present invention provides highly sensitive methods used for diagnosing and monitoring various diseases and disorders by detecting and analyzing "ultra short" (20-50 base pair) nucleic acids obtained from bodily fluids.
|OLIGONUCLEOTIDES FOR USE IN ALLELE-SPECIFIC PCR - The present invention relates to oligonucleotides complementary to a target polynucleotide, wherein the oligonucleotide comprises an LNA unit, a mismatch nucleobase, and an allele-specific nucleobase corresponding to an allele of the target polynucleotide. The invention further includes methods of using such oligonucleotides to detect and quantitate the frequency of particular alleles of a target polynucleotide.
|PROBE FOR DETECTING MUTATION IN JAK2 GENE AND USE THEREOF - A probe for detecting a mutation in the JAK2 gene is provided that can detect a target sequence containing a mutation even when the target sequence containing the mutation and a non-target sequence containing no mutation coexist, which are different only in a single base from each other. The probe to be used is an oligonucleotide that is at least one oligonucleotide having a sequence identical to that of a region extending from a cytosine base (C) at position 84 to be considered as the first base to any one of the 17th to 22nd bases in the direction toward the 5′ end in exon 12 of the JAK2 gene consisting of the base sequence of SEQ ID NO: 1, with the cytosine base (C) being the 3′ end. Even in the case of a sample containing both the JAK2 genes with a mutation that has occurred and without a mutation that has occurred, the use of such a probe in, for example, Tm analysis allows the former mutation to be detected. Preferably, the probe is labeled with a fluorescent dye.
|MULTIVARIATE DETECTION OF MOLECULES IN BIOSSAY - The invention relates to detection of target molecules in an assay, such as a bio-assay, and in particular to multi-variate detection of target molecules. A detector system is disclosed, the detection system comprising an optical guide element (
|MARKER GENES FOR USE IN THE IDENTIFICATION OF CHONDROCYTE PHENOTYPIC STABILITY AND IN THE SCREENING OF FACTORS INFLUENCING CARTILAGE PRODUCTION - The present invention relates to a set of genes which can be used to predict the potential of a cell population to form cartilage when implanted in vivo. The set of markers is used inter alia as a quality control of cells and in screening assays to evaluate the impact of compounds and conditions on the cartilage forming ability of cells.
|DISPOSABLE ARTICLES FOR ANALYSIS AND DIAGNOSTICS FOR A LABORATORY - The invention relates to disposable articles for a laboratory and in particular to prepared reaction vessels for conducting the polymerase chain reaction for analytical and diagnostic purposes. The invention further relates to a method for the stable storage and drying of minute amounts of oligonucleotides and reference nucleic acids in reaction vessels. The oligonucleotides and the nucleic acids are dried on the wall of the reaction vessel in the presence of 1 to 5 mM trehalose, without any further components.
|CANCER THERAPY PROGNOSIS - Methods and compositions based on FOXA1 expression to predict long-term disease-free survival in patients with breast cancer are disclosed. In ER+ positive patients, expression of FOXA1 is useful in identifying a subgroup of patients with a better prognosis. FOXA1 expression correlates with luminal subtype breast cancer, and serves as a clinical marker for luminal subtype breast cancer. Expression of FOXA1 is useful as a prognostic marker for an effective response tumors and as a predictive marker for a greater likelihood of response to an anti-hormonal therapy. Prognostic ability of FOXA1 in low-risk breast cancers is useful in treatment decision making.
|Methods and Compositions for Identifying Yeast - The invention relates to a method of identifying a specific yeast species in patient tissue or body fluid. The method comprises the steps of extracting and recovering DNA of the yeast species from the patient tissue or body fluid, amplifying the DNA, hybridizing a probe to the DNA to specifically identify the yeast species, and specifically identifying the yeast species. The invention also relates to a method of identifying a yeast mycotoxin in patient tissue or body fluid. The method comprises the steps of extracting and recovering the yeast mycotoxin from the patient tissue or body fluid, contacting the yeast mycotoxin with an antibody directed against the yeast mycotoxin, and identifying the yeast myocotoxin. Both of these methods can be used to determine if a patient is at risk for or has developed a disease state related to a yeast infection, and to develop an effective treatment regimen for the patient.
|Cell culture system for determinging the sensitizing, allergenic and/or irritating effect of a substance - The present invention refers to a cell culture system especially for investigating the sensitizing, allergenic and/or irritating effect of substances, comprising a first and a second compartment that can communicate with each other via a permeable interlayer, whereby the first compartment has an epidermis model and the second a cell culture based on immune cells.
|Method and kit for detection of early cancer or pre-cancer using blood and body fluids - This invention is related to a method for the detection of early or pre-cancer using DNA isolated from blood and body fluids. This invention provides an improved methylation-based PCR assay, a panel of methylated-based cancer-related gene markers for the detection of general cancer and a panel of unmethylation-based tissue- or cell-specific gene markers for discriminating different type of cancer detected from blood samples. This method couples a sequential cancer-related gene marker detection and tissue or cell-specific gene marker assay and is particularly useful as a simultaneous screening test for following type of cancer: lung, breast, ovarian, colon, stomach, prostatic, pancreatic and liver cancer.
|Method and system for protection and cross protection of algae and cyanobacteria from virus an bacteriophage infections - Virus contaminations of bioreactors can cause considerable losses in the industry and prevention of such contaminations is usually a major concern, especially in continuous cultures and particularly in outdoor/uncovered operations such as ponds or "racing ponds". Use of transgenic algae/cyanobacteria harboring introgressed virus/phage DNA fragments, cultured in these bioreactors/ponds will provide protection to a range of viruses/phages. Molecular mechanisms such as lysogeny and post transcriptional gene silencing (PTGS) are being exploited to produce protected algae/cyanobacteria with cross protective resistance against various viruses/phage, thus gaining bioreactor stability.
|Modified nucleosides and nucleotides and uses thereof - The invention is directed to modified guanine-containing nucleosides and nucleotides and uses thereof. More specifically, the invention relates to modified fluorescently labelled guanine-containing nucleosides and nucleotides which exhibit enhanced fluorophore intensity by virtue of reduced quenching effects.
|MICROFLUIDIC DEVICES - Methods and devices for the interfacing of microchips to various types of modules are disclosed. The technology disclosed can be used as sample preparation and analysis systems for various applications, such asDNA sequencing and genotyping, proteomics, pathogen detection, diagnostics and biodefense.
|Biomaker for ovarian and endometrial cancer: hepcidin - The present invention provides protein-based biomarkers and biomarker combinations that are useful in qualifying ovarian cancer status as well as endometrical cancer status in a patient. In particular, it has been found that hepcidin is a biomarker for both ovarian cancer and endometrial cancer and that a panel of biomarkers, including hepcidin, transthyretin and optionally other markers are useful to classify a subject sample as ovarian cancer or non-ovarian cancer. The biomarkers can be detected by SELDI mass spectrometry.
|DIRECT DETERMINATION OF VITAMIN D IN SERUM OR PLASMA - A method for quantitating vitamin D metabolites directly in blood plasma or serum, without the need for prior purification of the vitamin D metabolites, comprising a digestion of the serum proteins with a serine protease such as proteinase K and sequence of steps for inhibiting the proteinase K activity in the competitive binding analysis. The advantages of this method are its high accuracy over the whole range of physiologically relevant values and that it can be easily adapted for a fully automated analysis of serum and plasma samples.
|ANTIGEN DETECTION METHOD INVOLVING AN OLIGONUCLEOTIDE ENHANCED COLLOIDAL GOLD SIGNAL - The present invention refers to a rapid immunochromatographic test device for antigen detection, comprising a first and a second conjugate releasing pad, wherein the first conjugate pad comprises a gold conjugated protein linked first oligonucleotide and a gold conjugated antigen specific antibody, and the second conjugate pad comprises a gold conjugated protein linked second oligonucleotide, which second oligonucleotide is complementary to the first oligonucleotide. The present invention further refers to a use of such test device for antigen detection in urine or saliva, e.g. human choriogonadotropin (hCG) in urine. Embodiments of the test device are a test strip and a detection cup. The present invention also refers to a method for manufacturing such test device.
|RAPID IMMUNOCHROMATOGRAPHIC DETECTION BY AMPLIFICATION OF THE COLLOIDAL GOLD SIGNAL - The present invention relates to a method for rapid immunochromatographic detection of a target in a sample by double sandwich immunoassay detection, wherein the target is an antibody and/or an antigen, using different colloidal gold conjugates conjugated with a first and a second specific antibody or antigen and with at least one oligonucleotide and its at least one complementary oligonucleotide and/or at least one non-specific antibody and its related non-specific antigen, to a rapid immunochromatographic detection device, to uses of the method for detecting diseases or specific conditions, and to a method for the manufacture of the device as well as to a kit which comprises the device.
|POLYSACCHARIDE DERIVATIVES AND USES IN INDUCTION OF AN IMMUNE RESPONSE - The present invention generally provides compositions comprising a polysaccharide derivative, and methods of their preparation and use for the prevention or treatment of diseases caused by
|METHOD AND KITS FOR THE DIAGNOSIS OF DIABETES - Provided are methods for the detection and diagnosis of a predisposition for developing diabetes. The methods are based on the discovery that abnormal levels of the selected analyte in biological samples, typically blood samples, of patients who are at risk are supportive of a diagnosis of a predisposition for developing diabetes. At least one new biomarker for a predisposition for diabetes is thus disclosed, IGF-1. Other important biomarkers for diabetes are described, including but not limited to ZAG, clusterin, corticosteroid-binding globulin, lumican, and serotransferrin. Kits containing reagents to assist in the analysis of biological samples are also described.
|METHOD FOR SCREENING ANTI-CANCER COMPOUNDS INHIBITING FUNCTION OF TM4SF5 AND ANTI-CANCER COMPOSITION CONTAINING CHALCONE COMPOUNDS - The present invention relates to a method for screening an anticancer compound and an anticancer compound screened using the method, and more particularly, to a method for screening an anticancer compound, the method comprising: culturing cancer cells expressing the oncogenic protein transmembrane 4 L6 family member 5 (TM4SF5), expressed as the polypeptide of SEQ ID NO: 2, treating the cancer cells with an anticancer candidate, and determining that the anticancer candidate is an anticancer substance when the candidate exhibits antagonistic activity against tumor formation and metastasis based on several events through the molecular mechanism of TM4SF5. The present invention also relates to chalcone compounds screened to have anticancer activity using the method, and an anticancer composition comprising the compound as an effective ingredient.
|Use of N-Myristoyltransferase on Non-Tumor Tissue for Cancer Diagnosis - A diagnostic method and kit are disclosed for detection of cancer. Detection of elevated levels of N-myristoyltransferase (NMT) or NMT activity in blood or bone marrow, and specifically in peripheral blood mononuclear cells, can be used as a marker for cancer. The use of this method for detection of adenocarcinoma, such as colorectal cancer, is exemplified.
|CLONED GLUCAGON-LIKE PEPTIDE-2 RECEPTORS - The invention relates to nucleotides and amino acid sequences encoding Glucagon-like peptide-2 receptors, recombinant host cells transformed with such nucleotides, and methods of using the same in drug screening and related applications.
|pH-Sensitive Fluorescent Probe - A compound represented by the following general formula (I):
|NANOPARTICLE AND MICROPARTICLE BASED DETECTION OF CELLULAR PRODUCTS - Embodiments of the present invention relate to devices and methods for detecting cellular products using detection particles having product-specific detection reagents and having a characteristic spectral feature. In particular, devices and methods are provided for measuring secreted cellular products including cytokines. Detection substrates, include microwells having product-specific capture reagents thereon or comprising hydrophobic membranes are described having greater capability to detect products from individual cells in a mixture of heterogeneous cells. With the use of multiple detection particles, multiple cellular products can be detected in a single well. Additionally, using the inherent spectral properties of detection particles, no enzymatic reactions are needed to visualize a secreted product, thereby increasing the sensitivity, reproducibility and ease of use.
|MICROFLUIDIC DEVICE INCLUDING UNIT FOR EVALUATING CAPTURE MATERIAL AND METHOD OF EVALUATING CAPTURE MATERIAL - Provided are a microfluidic device including a unit for evaluating a capture material and a method of evaluating a capture material.
|Novel Nucleotide and Amino Acid Sequences, and Assays and Methods of Use Thereof for Diagnosis of Lung Cancer - Novel markers for lung cancer that are both sensitive and accurate. These markers are overexpressed in lung cancer specifically, as opposed to normal lung tissue. The measurement of these markers, alone or in combination, in patient samples provides information that the diagnostician can correlate with a probable diagnosis of lung cancer. The markers of the present invention, alone or in combination, show a high degree of differential detection between lung cancer and non-cancerous states.
|Enzyme-linked Immunosorbent Assay (ELISA) for Canine Hepcidin - The present invention relates to the use of hepcidin-specific antibodies for the detection of hepcidin in biological samples for the diagnosis of diseases and disorders related to iron metabolism. Kits useful in screening various subjects suspected of having diseases or disorders associated with iron metabolism are also provided.
|Method of Immunoassaying A Component to be Measured - A method of immunoassaying a component to be measured in a sample containing hemoglobin, which comprises reacting a component to be measured in a sample containing hemoglobin with an antibody capable of binding to the component in the presence of a bile acid derivative different from a bile acid derivative that is inherently contained in the sample; a method of suppressing an interference of hemoglobin in immunoassaying a component to be measured in a sample containing hemoglobin, which comprises reacting a component to be measured in a sample containing hemoglobin with an antibody capable of binding to the component in the presence of a bile acid derivative different from a bile acid derivative that is inherently contained in the sample; a reagent of immunoassay of a component to be measured in a sample containing hemoglobin, which comprises a bile acid derivative, are described.
|PH Tolerant Luciferase - Use of a luciferase that has a mutation of at least one amino acid selected from the group consisting of positions 14, 35, 182, 232 and 465, where the numbering is according to the sequence of the luciferase from
|MICROFLUIDIC DEVICE WITH A CYLINDRICAL MICROCHANNEL AND A METHOD FOR FABRICATING SAME - A method of manufacturing a microfluidic device having at least one cylindrical microchannel includes providing a substrate, casting an uncured polymer matrix solution onto the substrate, embedding an elongated rod in the uncured polymer matrix solution, curing the polymer matrix solution to form a solidified body, and extracting the elongated rod to form the cylindrical microchannel in the solidified body. In another embodiment, the method includes forming an optical feature on a surface of the microfluidic device. A microfluidic device is also provided, the device including a polymer body, and at least one cylindrical microchannel in the polymer body, the cylindrical microchannel having a diameter between approximately 40 ?m and 250 ?m, inclusive. An additional microfluidic device is provided that functions as an optofluidic spectrometer. The optofluidic spectrometer includes a polymer body, a diffraction grating integrated within the polymer body, and a cylindrical microchannel behind the diffraction grating on the polymer body.
|ASSAY SYSTEM FOR ADENOSINE TRIPHOSPHATE AND CREATINE KINASE - An assay method includes providing a luminescent nanocrystal; combining a solution having an adenosine triphosphate molecule; and displaying a light emission by the luminescent nanocrystal and the solution combined.
|Methods - A method for identifying a compound expected to be useful in modulating, for example inhibiting, LRRK2 protein kinase activity, the method comprising the steps of (1) determining whether a test compound modulates, for example inhibits, the protein kinase activity of a LRRK2 polypeptide on a substrate polypeptide and (2) selecting a compound which modulates, for example inhibits, the said LRRK2 polypeptide protein kinase activity, wherein the substrate polypeptide comprises the sequence (W/F/R/K)(W/F/R/K)(R/K)(F/W/H/R)(Y/W/R)(
|Method for predicting response of cancer patient to anticancer drug treatment - A method predicts a response of a cancer patient to anticancer drug based on a cell cycle profile score obtained by analyzing a malignant tumor of the cancer patient, wherein the method can predict a disease outcome including a complete response, a partial response, stable disease, no response, and time to progression of disease as patient's response to anticancer drug therapy.
|Method for the purification of heat shock proteins - Recombinant purified DnaK—having a ATPase activity without the addition of an other chaperone protein—essentially free of T-cell stimulating impurities.
|PROCESS AND KIT FOR MEASURING THE CONDITION OF THE FIBRINOLITIC SYSTEM - The invention relates to an assay and a kit for the determination of the status of the fibrinolytic system. In particular the invention relates to a method for the determination of the status of the fibrinolytic system from tear fluid samples. Additionally the invention relates to a sterilized, calibrated capillary equipped with a plastic balloon, suitable for tear fluid sampling, and a kit for the assessment of the status of the fibrinolytic system, or for the determination of its balance, comprising a sampling capillary, reaction sheets, color scale to help the evaluation, and reagents
|DIAGNOSIS METHOD FOR FATTY LIVER DISEASE, DIAGNOSIS APPARATUS, DIAGNOSIS PROGRAM, DIAGNOSTIC AGENT, AND METHOD FOR SCREENING FOR THERAPEUTIC AGENT FOR FATTY LIVER DISEASE - There is provided an examination method which is simpler than conventional liver biopsy and enables the diagnosis of steatohepatitis. This diagnostic method comprises the steps of measuring the concentration of choline contained in a blood-derived sample collected from a subject; and determining the presence of fatty liver disease, severity of the disease, or a therapeutic effect on the disease based on the choline concentration.
|Generic Assay for Monitoring Endocytosis - A method for monitoring the internalisation of a cell surface molecule of interest is provided utilizing a detectable lectin.
|Fluorescent Ion Indicators for Cadmium and Lanthanide Ion Detection - The present invention provides a metal chelator and methods that facilitate binding, detecting, monitoring and quantitating of heavy metal ions in a sample. This metal chelating moiety has the following formula
|OPTICAL SENSOR AND METHOD FOR INDICATING THE AGE OR QUALITY OF A NATURAL PRODUCT - The present invention relates to the field of analyzing the age and/or quality of certain natural products, for example foods. The invention also relates to devices for analyzing said age and/or quality as well as to methods for preparing such devices, to methods for analyzing natural products and to their use.
|METHOD FOR FLUOROMETRICALLY DETERMINING PHOTOSYNTHESIS PARAMETERS OF PHOTOAUTOTROPIC ORGANISMS, DEVICE FOR CARRYING OUT SAID METHOD AND A MEASUREMENT CHAMBER - The invention can be used in biology and for environmental studies using fluorimeters. The inventive method consists in producing exiting light pulses having equal amplitude and modifiable duration, in measuring fluorescent chlorophyll characteristics at a constant background illumination simulating the irradiation intensity of an object during studies in the natural conditions and after the adaption thereof in the dark and in determining the state of a photosynthetic apparatus according to the entirety of fluorescent intensity values. The inventive device comprises the even number of measuring light sources, a current stabiliser of the light sources, the outputs of which are connected to electric inputs of the light sources, the input of which is connected to a control unit and a natural irradiation sensor is connected to the current stabiliser of the light sources through said control unit. A measurement chamber comprises the even number of light sources which are arranged by pairs diametrically oppositely to each other in one plane which is perpendicular to the axis of the body.
|Method and System for Artifact Reduction - A method is presented for obtaining characteristics of a target physical entity by providing an excitation signal to the target physical entity and simultaneously measuring the response of the target physical entity. Analog signal processing is performed on the measured response to eliminate artifacts arising from a signal path outside the target physical entity and determining the characteristics from the signal processed measured response. The excitation signal and the analog signal processing are selected such that after analog signal processing of the measured signal, the analog measured signal contains artifacts which are localized in time.
|Novel fluorescent dyes and compounds, methods and kits useful for identifying specific organelles and regions in cells of interest - The present invention provides dyes and labeled reagents that may be used in the detection or quantification of desirable target molecules, such as proteins, nucleic acids and cellular organelles. Dyes are provided that may be used free in solution where the binding of the dye to the target molecule provides signal generation. Dyes provided in this invention can comprise reactive groups that may be used to attach the dyes to probes that will bind to desirable target molecules. The novel dyes of the present invention have been substituted with specific groups to provide beneficial properties.
|Biotin-facilitated transport in gram negative bacteria - Biotinylation of compounds such as peptides and peptidomimetics facilitates illicit transport of the compounds into Gram negative bacteria.
|Density-based cell detection system - The invention provides a low-cost method for identifying and/or measuring a subpopulation of cells in a biological sample, such as a subpopulation of CD4-positive cells in a whole blood sample. In accordance with the invention, one or more cell surface markers are identified on a subpopulation of interest, which collectively are present in higher numbers on the cells of the subpopulation than on cells not in the subpopulation of interest. A probe comprising a binding compound and a density label are combined with the sample and the resulting mixture is centrifuged or sedimented through a density medium in a capillary. Labeled cells of interest pass through the density medium and stack at the bottom of the capillary where they may be visually detected and quantified by the height of the stack.
|Method and system for detection and/or characterization of a biological particle in a sample - The present invention provides a method and system for monitoring, detecting, and/or characterizing a biological particle that may be present in a sample whereby the method may be accomplished non-invasively by utilizing a time-dependent spectroscopic technique to obtain at least two measurements of a growth composition comprising a sample and correlating said measurements for the detection and/or characterization of a biological particle, that may be present in the sample.
|METHOD AND APPARATUS FOR DETECTING AND QUANTIFYING BACTERIAL SPORES ON A SURFACE - A method and an apparatus for detecting and quantifying bacterial spores on a surface. In accordance with the method: bacterial spores are transferred from a place of origin to a test surface, the test surface comprises lanthanide ions. Aromatic molecules are released from the bacterial spores; a complex of the lanthanide ions and aromatic molecules is formed on the test surface, the complex is excited to generate a characteristic luminescence on the test surface; the luminescence on the test surface is detected and quantified.
|IN SITU HEAT INDUCED ANTIGEN RECOVERY AND STAINING APPARATUS AND METHOD - An automated microscope slide staining system and staining apparatus and method that features a plurality of individually operable miniaturized pressurizable reaction compartments or a pressurizable common chamber for individually and independently processing a plurality of microscope slides. The apparatus preferably features independently movable slide support elements each having an individually operable heating element.
|MUTANT ARABINOSE PROMOTER FOR INDUCIBLE GENE EXPRESSION - An L-arabinose inducible expression system comprising a mutant arabinose promoter. This system exhibits an increase in heterologous protein production upon induction with L-arabinose and comprises a mutant araB promoter and an AraC transcription binding region. This system retains the tight regulatory control characteristic of the wild type arabinose operon.
|MODIFIED CHONDROITIN SYNTHASE POLYPEPTIDE AND CRYSTAL THEREOF - Disclosed are: (A) a polypeptide consisting of the amino acid sequence of SEQ ID NO:2, or (B) a polypeptide comprising an amino acid sequence of SEQ ID NO:2 including deletion, substitution or addition of one or several amino acid residues and having chondroitin synthase activity; a nucleic acid encoding the polypeptide; a method for producing the polypeptide, comprising at least the steps of: (1) expressing the nucleic acid to produce the polypeptide; and (2) collecting the polypeptide produced in the step (1); and a crystal of the polypeptide. The crystal may be a monoclinic or tetragonal crystal.
|PROTEINS WITH ESTERASE ACTIVITY - The invention relates to novel proteins having esterase activity, to mutants thereof, to nucleic acid sequences coding therefor, to expression cassettes, vectors and recombinant microorganisms; to methods for preparing said proteins and to the use thereof for enzymic, in particular enantioselective enzymic, ester hydrolysis or transesterification of organic esters.
|ISOLATION AND CHARACTERIZATION OF A NOVEL PYTHIUM OMEGA 3 DESATURASE WITH SPECIFICITY TO ALL OMEGA 6 FATTY ACIDS LONGER THAN 18 CARBON CHAINS - The present invention relates to a polynucleotide encoding an omega 3 (ω-3) desaturase from
|NOVEL NUCLEIC ACID MOLECULES - The present invention relates to a novel nucleic acid molecule encoding an amino acid sequence, which is capable of forming a cyclic structure. Cyclization may occur within a cell or cell membrane, or linear forms of the molecules may be circularised or partially circularised, in vitro using isolated enzyme systems or chemical means. The cyclised amino acid sequence is generally in the form of a stabilized folded structure such as acyclic knotted peptide, polypeptide or protein or functional equivalent. The nucleic acid molecules and cyclic and linear peptides are useful inter alia in the generation of molecules having animal or plant therapeutic properties, as well as in a range of diagnostic, industrial and agricultural, including horticultural, applications. Of particular importance is the use of these molecules in the protection of plants, such as crop plants, from pest and/or pathogen infestation.
|MAMMALIAN CHEMOKINES; RECEPTORS; REAGENTS; USES - Novel chemokines and 7 transmembrane receptors from mammals, reagents related thereto, including purified proteins, specific antibodies, and nucleic acids encoding the chemokines and receptors are disclosed. Methods of using the chemokines, receptors, reagents and diagnostic kits are also provided.
|Droplet Actuator Devices and Methods Employing Magnetic Beads - A method of providing a droplet in contact with a magnetically responsive bead and having a reduced quantity of a substance. The method generally includes the steps of (a) providing a droplet actuator (
|SYSTEMS AND METHODS FOR THE AMPLIFICATION OF DNA - A system for amplifying nucleic acids is disclosed which, in one embodiment, includes a fluidic device having a sample channel and a heat exchange channel disposed sufficiently close to the sample channel such that a heat exchange fluid in the heat exchange channel can cause a sample in the sample channel to gain or lose heat at desired levels. In one illustrative embodiment, the system further includes three reservoirs coupled to the heat exchange channel and a temperature control system configured to heat fluids stored in the respective reservoirs at different temperatures. One or more pumps and a controller are configured to cause fluid stored in the reservoirs to enter and flow through the heat exchange channel at different times.
|COMPOSITION FOR CLEAVING AND/OR CONNECTING SINGLE STRAND DNA - It is an object of the present invention to provide a composition for catalyzing the cleavage of a single-stranded DNA and the binding of such single-stranded DNA. The present invention provides a composition for cleaving a single-stranded DNA and/or binding the 5′-terminus of such single-stranded DNA to the 3′-terminus thereof, which comprises an Ev1 protein. Moreover, the present invention also provides a composition for cleaving a single-stranded DNA and/or binding the 5′-terminus of such single-stranded DNA to the 3′-terminus thereof, which further comprises a Rad51B protein and/or a DNA topoisomerase type I protein, as well as the Ev1 protein.
|MULTI-COMPONENT INHIBITORS OF NUCLEIC ACID POLYMERASES - The present invention provides multi-component inhibitors of nucleic acid polymerases, methods of making, and methods of using same. One component of the multi-component inhibitor is a molecule that binds to a polymerase (i.e., a polymerase-binding molecule (PBM)), but does not thereby substantially inhibit its polymerase activity. Another component is a molecule or complex of molecules that binds to a PBM (i.e., a PBM-binding molecule). The combination of the PBM and PBM-binding molecule/complex substantially inhibits polymerase activity. The disclosed multi-component inhibitors are useful for DNA sequencing, nucleic acid amplification, cloning and synthesis, and the like.
|ENZYME COMPOSITIONS AND METHODS FOR THE IMPROVED ENZYMATIC HYDROLYSIS OF CELLULOSE - A process for the enzymatic hydrolysis of cellulose to produce a hydrolysis product comprising glucose from a pretreated lignocellulosic feedstock and enzymes for use in the process are provided. The process comprises partially hydrolyzing an aqueous slurry of a pretreated lignocellulosic feedstock with cellulase enzymes, one or more than one β-glucosidase enzyme and a binding agent for binding the β-glucosidase enzyme to fiber solids present in the aqueous slurry. The unhydrolyzed fiber solids are then separated from the hydrolyzed slurry. The separated fiber solids thus obtained are then re-suspended in an aqueous solution to produce a re-suspended slurry. The hydrolysis is then continued to produce the hydrolysis product comprising glucose.
|L-GLUTAMIC ACID-PRODUCING MICROORGANISM AND A METHOD FOR PRODUCING L-GLUTAMIC ACID - A coryneform bacterium that is modified by using a yggB gene so that L-glutamic acid-producing ability is enhanced as compared to a non-modified strains is cultured in a medium to cause accumulation of L-glutamic acid in the medium or bacterial cells, and L-glutamic acid is collected from the medium or cells.
|METHOD FOR THE CHEMO-SELECTIVE ENZYMATIC HYDROLYSIS IF A DIESTER COMPOUND FOR PREPARING A MONOESTER MONOACID COMPOUND - The invention relates to a synthesis process.
|PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY ENRICHED BETA-AMINO ALCOLHOLS STARTING FROM GLYCINE AND AN ALDEHYDE IN THE PRESENCE OF A THREONINE ALDOLASE AND A DECARBOXYLASE - The invention relates to a process for the preparation of an enantiomerically enriched β-amino alcohol, wherein glycine or a glycine salt and an aldehyde are reacted in the presence of a threonine aldolase and a decarboxylase to form the corresponding enantiomerically enriched β-aminoalcohol, and wherein at least either the threonine aldolase or the decarboxylase is β-selective. In a preferred embodiment of the invention at least either the threonine aldolase or the decarboxylase is enantioselective.
|Solubilization of algae and algal materials - Methods for solubilizing algae or algal material are provided to facilitate the recovery of oil or lipids, as well as hydrocarbons and carbohydrates, from algae or algal material. The methods involve contacting algae or algal material with an oxoacid ester or thioacid ester of phosphorus or a mixture of an oxoacid of phosphorus and/or an alcohol to form a mixture thereof under conditions effective to solubilize the algae or algal material. These methods optionally further comprise bioconversion of the solubilized algae or algal material to form a composition suitable for recovery of oils and non-oil chemicals.
|MICROBIOLOGICAL PRODUCTION OF 3-HYDROXYISOBUTYRIC ACID - The present invention relates to a cell which has been modified in comparison with its wild type in such a way that it is capable of forming more, by comparison with its wild, 3-hydroxyisobutyric acid or poly-hydroxyalkanoates based on 3-hydroxyisobutyric acid via methylmalonate-semialdehyde or 3-hydroxybutyryl-coenzyme A as precursors. The invention also relates to a method of generating a genetically modified cell, to the genetically modified cell obtainable by these methods, to a method of producing 3-hydroxyisobutyric acid or polyhydroxyalkanoates based on 3-hydroxyisobutyric acid, to a method of producing methacrylic acid or methacrylic esters, and to a method of producing polymethacrylic acid or polymethacrylic esters. The present invention furthermore relates to an isolated DNA, to a vector, to the use of this vector for transforming a cell, to a transformed cell, and to a polypeptide.
|METHOD FOR PRODUCING AN ORGANIC ACID - An organic acid is produced by allowing a bacterium which has an ability to produce an organic acid and has been modified so that expression of the sucE1 and mdh genes are enhanced, or a product obtained by processing the bacterium, to act on an organic raw material in a reaction mixture containing carbonate ions, bicarbonate ions, or carbon dioxide gas, and collecting the organic acid.
|NOVEL GENES FOR THE FERMENTATIVE PRODUCTION OF HYDROXYTYROSOL - The present invention relates to the use of polynucleotides and polypeptides as biotechnological tools in the production of hydroxytyrosol from microorganisms, whereby a modification of said polynucleotides and/or encoded polypeptides has a direct or indirect impact on yield, production, and/or efficiency of production of hydroxytyrosol in said microorganism. The invention also features polynucleotides comprising the full length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. Also included are methods/processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms. The invention also relates to genetically engineered microorganisms and their use for the production of hydroxytyrosol.
|Genetically Modified Cyanobacteria for the Production of Ethanol - The invention provides novel compositions of matter for the production of ethanol from carbon dioxide and water. Particularly, the invention provides photoautotrophic organisms having a first and second genetic modification, wherein the first genetic modification improves the ethanol production from organisms having the second genetic modification.
|METHODS FOR PRODUCING BIOFUELS AND COMPOSITIONS FOR USE IN BIOFUEL PRODUCTION METHODS - Beneficial virus, such as phage, is used in fermentation methods and other techniques for producing biofuels. The beneficial virus (e.g., phage) may be targeted toward microorganisms (e.g., bacteria, etc.) that undesirably affect the fermentation or biofuel production process. Beneficial virus targeted toward microorganisms that undesirably affect the product or by-product of such a process, further processing, or the results of such further processing may also be incorporated into the fermentation or biofuel production process. Compositions that include beneficial viruses, such as phage, that are useful in such processes are also disclosed.
|PROCESS FOR COMPREHENSIVELY UTILIZING STEAM EXPLODED RADIX PUERARIAE AND DEVICE THEREFOR - The invention provides a process for co-producing ethanol and Radix Puerariae flavones and utilizing Radix Puerariae fibers from Radix Puerariae by way of clean solid state fermentation, and the device used therein. The process comprises the following steps: providing Radix Puerariae as raw material; pretreating the Radix Puerariae raw material by steam explosion; producing and separating ethanol by continuous coupled solid state fermentation; filtering off fermentation residues; and extracting and purifying Radix Puerariae flavones from the filtrate. The process achieves an effective and comprehensive utilization of Radix Puerariae.
|ALGACULTURE SYSTEM FOR BIOFUEL PRODUCTION & METHODS OF PRODUCTION THEREOF - Embodiments of algaculture systems to generate biofuel are herein provided. In one embodiment, an algaculture system includes a photo-bioreactor (PBR) including pump/tank assembly in communication with an input portion of a solar collector. The pump/tank assembly may act as a reservoir and/or agitator for a mixture of algae, water and nutrients (hereinafter, "algae media") which mixture may be pumped into the solar collector. The solar collector may comprise a plurality of interconnected tubes (in various configurations) with a plurality of axial vortex flow generators positioned at an intake portion of each tube. Sensors, ports for input of nutrients and gasses, and ports for removal of gasses may be located in fittings between sections of tubing. An output portion of the solar collector may be in fluid communication with a continuous harvester which may redirect mature algae for processing thereof.
|METHOD FOR THE SELECTION AND/OR THE PROCESSING OF PARTICLES, IN PARTICULAR CELLS - Method for the selection or the processing of first particles sensitive to the application of an external stimulus including the step of producing, through the application of the external stimulus, the permeabilization of at least a selected first particle, consisting in the organization of the first particles through a first force field, to generate a second force field substantially placed in proximity of at least a selected first particle to be permeabilized.
|MECHANICAL LYSIS ARRANGEMENTS AND METHODS - Methods and arrangements to lyse a biological sample are described. The arrangements comprise a lysis tube containing the sample, one or more electromagnets generating a magnetic field, and one or more permanent magnets inside the lysis tube. The permanent magnets move and lyse the sample when a magnetic field is generated by the electromagnets.
|METHOD FOR THE SURFACE TREATMENT OF SOLID SUBSTRATES - The invention relates to a process for the chemical modification of a surface of a support, in which said surface contains available hydroxyl groups and lacks metals or metallic alloys. According to the invention, the surface is treated with orthophosphoric acid. The surface thus treated can be used to immobilize biomolecules, cellular membranes, liposomes, cells or tissue sections. The invention is suitable for use in biotechnology, proteomics, genomics, pharmacology and histology in order to carry out studies on immobilized products.
|TAILORED CONTROL OF SURFACE PROPERTIES BY CHEMICAL MODIFICATION - A process for producing a substrate having an adhesive surface, which process comprises: (a) contacting the substrate with a carbene precursor, which carbene precursor is a compound of the following formula (1): whose substituent groups are SP defined herein, provided that when R is aryl or heteroaryl, said aryl or heteroaryl may be substituted by one, two, three, four or five groups, which groups are independently selected from various groups including -L
|PROCESS FOR IMMOBILIZATION OF PROTEIN CATALYSTS, PRODUCT, AND USE - An immobilized protein catalyst is prepared by applying an adhesive to a polymeric support, applying a layer of a globular protein over the layer of adhesive, binding a crosslinking agent to the protein layer, and binding the protein catalyst by reaction with the crosslinking agent.
|SPINOSYN-PRODUCING POLYKETIDE SYNTHASES - The invention provides, biologically active spinosyns, hybrid spinosyn polyketide synthases capable of functioning in
|METHODS AND COMPOSITIONS FOR REVERSING P-GLYCOPROTEIN MEDICATED DRUG RESISTANCE - A method for inhibiting therapeutic drug resistance within a cell over-expressing a membrane protein is provided. The method comprises synthesizing a dimeric prodrug inhibitor of a monomeric therapeutic agent; administering the dimeric prodrug inhibitor to the membrane protein together with the monomeric therapeutic agent; and occupying at least one substrate binding site of the membrane protein with the synthesized dimeric prodrug to allow the monomeric therapeutic agent to accumulate within the cell. The dimeric prodrug inhibitor contains a crosslinking agent that is adapted to breakdown under reducing conditions within the cytosol of the cell to cause the dimeric prodrug to revert back to a form equivalent to the monomeric therapeutic agent.
|Novel Staphylococcus aureus: Bacteriophage and Uses Thereof - The present invention is directed to isolated bacteriophage having strong lytic activity against strains of
|NOVEL MICROORGANISM CAPABLE OF MICROBIALLY DECOMPOSING CHLORO-, METHYLTHIO- AND METHOXY-TRIAZINE AGRICHEMICALS - Disclosed are: a novel microorganism which can decompose a methylthiotriazine compound (particularly, simetryn, dimethametryn, prometryn), a chlorotriazine compound (particularly, simazine, atrazine, propazine) and a methoxytriazine compound (particularly, simeton, atraton, prometon) which have been frequently used as agrichemicals or the like; and a method for decomposing a methylthiotriazine compound, a chlorotriazine compound and/or a methoxytriazine compound by using the microorganism. Specifically disclosed are: a novel bacterium
|AMMONIUM TRANSPORTER PROMOTERS FOR GENE EXPRESSION IN OLEAGINOUS YEAST - The promoter region associated with the
|NON-RECOMBINANT SACCHAROMYCES STRAINS THAT GROW ON XYLOSE - The present invention relates to methods for producing
|SYSTEM AND METHOD FOR CONTINUOUS FERMENTATION OF ALGAE - The present invention is a method for fermentation of algae or algaefaction method. The method includes feeding a hydrocarbon composition into a gasifier and pre-heating a biomass stream from a fermentation reactor. The biomass stream includes a liquid portion, a catalyst, and a biomass solids portion ranging between 15-92% by weight ofthe biomass stream. The biomass solids portion is algae or algal solids. The biomass stream is pre-heated to a temperature range between 200° F. and 500° F. Both the syngas and the pre-heated biomass stream are injected as a mixture into a reactor, where the mixture is separated into a gas component, liquid component, and solids component. The solids component is algal crude, which can be collected for processing as transportation fuels. The gas component is a lower temperature syngas, which can also be collected for processing as electricity or transportation fuels.
|METHOD FOR THE VOLUME AND BULK REDUCTION OF DOMESTIC WASTE - A method for the volume and bulk reduction of domestic waste is disclosed, comprising comminution of the domestic waste, separation of the organic fraction of the domestic waste, generation of biogas from the separated organic fraction by anaerobic fermentation along the principal of dry fermentation in a biogas plant, relocation of the organic fraction from the biogas plant into an aerobization container, aerobization and composting of the organic fraction by supplying air, and drying of the composted organic fraction by injection of air.
|DEVICES AND METHODS FOR PRODUCTION OF CELL AGGREGATES - A microwell device comprises a fluid vessel having a bottom region. A microwell plate is at the bottom region. The microwell plate comprises an upper region defining an upper plane. A plurality of microwells extend downwardly from the upper plane. Each of the microwells comprises an axis extending perpendicularly to the upper plane. Each of the microwells comprises a sidewall. The sidewall of at least one of the microwells has at least one wall component extending inwardly towards the axis.
|Cell Fusion Chip - (Problems) To provide a cell fusion chip, which allows to perform a cell fusion on a single chip, excels in the operating efficiency, does not require experience so much in cell feed or recovery, and has no risk of the contamination to the cells during the operation.
|BLOOD TEST DEVICE - It is intended to make it easy to recognize the attachment site of a blood sensor in a blood test device to which the blood sensor is attached by insertion. Especially, it is attempted to make the recognition of the attachment site easy and facilitate the insertion of a blood sensor which is to be attached to a blood test device by a person with visual impairment (in particular, a patient suffering from diabetic retinopathy) for the daily measurement of blood glucose level. More specifically speaking, it is intended to provide a blood test device comprising a housing; an electrical circuit unit contained in the housing; and an attachment site for inserting a blood sensor thereinto that is exposed on the surface of the housing; wherein the surface of the attachment site has a color which is lighter than the surface color of the housing and distinguishable by a patient having impairment in the blue cone.
|Blood Glucose Tracking Apparatus and Methods - A measurement module for glucose testing includes a glucose testing measurement module housing, a test strip receptacle formed in the housing, and a connector portion formed in the housing and shaped to permit mechanical removable attachment of the housing to a hand-held computer. Electronics determine the amount of glucose present in a sample of body fluid, when the test strip is positioned in the receptacle and the body fluid is placed on a test strip, and communicate the glucose amount to the hand-held computer via the connector portion.
|Method for the visual detection of specific antibodies by the use of lateral flow assays - This disclosure teaches a method and composition for detecting the presence of class specific antibodies reactive with analytes such as bacteria, allergens, autoimmune antigens, viral proteins, haptens, and carbohydrates by lateral flow techniques. In one embodiment of the disclosure, a test sample is added to the test strip, which then migrates to the site of the immobilized allergens, thereby forming a first antibody IgE-allergen complex. A chase release buffer is added upstream to or from the site of the labeled anti-IgE antibodies, which is itself upstream from the sample site. The anti-IgE antibodies migrate downstream to the site of immobilized first complex, thereby forming a second complex indicating the presence of class specific IgE antibodies in the test specimen. In another embodiment of the disclosure, a liquid form of the labeled anti-IgE antibodies can be added to the test strip after the first complex has been formed.
|Intelligent multifunctional medical device apparatus and components - The multifunctional medical device contains system on chip (SoC) computation functionality to organize several functional modules consisting of analytical, diagnostic and therapeutic tasks in the microfluidic assembly. Micro-valves, micro-tubes, micro-wires and gates organize the chambers of the flexible modules which hold multiple chemical and biological agents for combination on demand.
|ORGANIC SUBSTANCE DETECTING DEVICE AND ITS MANUFACTURE METHOD - A plurality of gold fine particles are discretely dispersed on and fixed to a principal surface of a substrate. Each of molecular probes is bonded to the gold fine particle at one end of the molecular probe. The molecular probe fixes a target capture portion at a tip thereof. The target capture portion has behavior of being specifically bonded to an organic molecule.
|Systems and Methods for Generating Compost - Systems and methods for the generation of compost are provided. In one embodiment, the system for generating compost comprises a positively aerated floor, a semi gas and liquid impermeable compost cover sized to cover a compost biomass pile placed on the positively aerated floor, and a suction system positioned under or substantially close to the compost cover and generally near a top of the compost biomass pile, wherein the floor comprises a plurality of channels connected to at least one gas flow pipe installed below or above grade, wherein gas drawn by suction system at the top of the biomass compost pile maintains a negative pressure across the compost cover, thereby generating suction between the compost cover and the top of the compost biomass pile, and wherein the compost cover directs substantially all of the gas flow towards the suction system.
|Closed photobioreactor system for continued daily in situ production of ethanol from genetically enhanced photosynthetic organisms with means for separation and removal of ethanol - The invention provides a device for growing genetically enhanced aquatic photoautotrophic organisms in a stable culture, causing said organisms to produce ethanol, and then separating, collecting, and removing the ethanol in situ.
|NOVEL HUMAN ANDROGEN RECEPTOR ALTERNATIVE SPLICE VARIANTS AS BIOMARKERS AND THERAPEUTIC TARGETS - The present invention relates to novel androgen receptor splice variants (AR3, AR4, AR4b, AR5 and AR8) and variants and fragments thereof which have a role in the progression of androgen independent prostate cancer. The invention further relates to compositions and methods which can be used to identify and treat prostate cancer based on these novel androgen receptor splice variants, as well as methods for screening agents which modulate the activity and/or expression of the androgen receptor splice variants. Vectors, host cells and recombinant methods for producing the same and transgenic animals are also provided.
|Juvenile hemochromatosis gene (HFE2A), expression products and uses thereof - Polynucleotide and polypeptide sequences for HFE2A, as well as mutations associated with juvenile hemochromatosis, and methods of utilizing these for the screening and identification of agents for the treatment of diseases of iron metabolism, including small organic compounds, are disclosed along with methods of treating and/or ameliorating diseases of iron metabolism, especially in human patients are disclosed. Diagnostic compounds, kits and methods using HFE2A are also described.
|METHODS OF STIMULATING EXPANSION OF HEMATOPOIETIC STEM CELLS - The present invention relates, in general, to hematopoietic stem cells (HSC) and, in particular, to methods of stimulating expansion of hematopoietic stem cells and to agents suitable for use in such methods.
|XENO-FREE CULTURE CONDITIONS FOR HUMAN EMBRYONIC STEM CELLS AND METHODS THEREOF - The present disclosure provides novel culture system and methods for culturing and propagating hESCs in a substantially undifferentiated state for several passages. The ability to grow such cells without differentiation has important applications for therapeutic uses of ES cells for treating human disorders using tissue transplantation and/or gene therapy techniques. In particular, the disclosure further relates to conditioned medium obtained from human germ lineage derived feeder cells (GLDF). The hESC lines are derived, cultured and propagated in substantially undifferentiated state using the conditioned media from GLDF cells of the disclosure. In particular, the disclosure relates to the xeno-free derivation, culture and propagation of hESCs using conditioned medium of GLDF cells obtained thereof.
|NOVEL METHODS AND REAGENTS DIRECTED TO PRODUCTION OF CELLS - The present invention provides methods and materials to modulate and grow stem cells by contacting stem cells with a binder recognizing terminal glycan structures of stem cells. The modulation can be morphological change, change in differentiation status, biological status or adherence. The materials provided in the present invention are also useful to screen such a binding agents and binders.


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Through the ages the penis has been honoured and worshipped. Now we see exactly what this means.
And it is absolutely clear why it arouses such strong feelings of desire. The petite Japanese worshipper gives a whole new meaning to the phrase "Whole body massage" as she uses all of herself to honour the man.
This ground-breaking film lingeringly explores the contrast between the soft delicacy of the feminine and the rock-hard firmness of the masculine.
Runtime: 49:50 Minutes Format: Full HD 1080p File Size: 618 MB
As A CHERISHED member of Hegre.com you'll get a 15% discount ON ALL purchases from our shop.
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subset: commoncrawl


text:
Best Fishing Times: 4:48AM to 6:48AM, and 10:47PM to 12:47AM
Alternate Fishing Times: 10:17AM to 12:17PM
Fishing Hellcat Lake, AL on 5/26/2017 will be best from 4:48AM through 6:48AM, and from 10:47PM to 12:47AM. If those times won't work for you, 10:17AM to 12:17PM looks promising. Remember to adjust these times based on barometric pressure, and weather changes.


text:
short for fence. it has been used most recently by cool kids on the east coast and in the midwestern US, but is believed to have originated in the SanFran area
by 3timesalady April 09, 2008
There are many Harry Potter fen in the world.
by notemily September 10, 2003
verb often used by black people. It's a means of denoting a future action by one or more individuals.
by robbdachi December 20, 2008
A incredibly intelligent and person, whom is capable of doing anything and everything.
by BrandLuon May 24, 2011
by lil mama qt April 15, 2008
The Urban Dictionary Mug
One side has the word, one side has the definition. Microwave and dishwasher safe. Lotsa space for your liquids.Buy the mug
by goddess erin March 24, 2005
by goddess erin March 24, 2005


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American Council on Exercise4851 Paramount DriveSan Diego, California 92123
Receive unique offers and information on specialist programs, workshops, free webinars and more.
YogaFit® Kids Teacher Training Program is a continuing education course delivered via user-friendly DVD and workbook for anyone who wants to learn how to teach children yoga. We will teach you to instruct kids and teens in basic poses and mindful movement, breathing activities, share circles, laughter yoga, partner yoga, and many other cooperative learning games and activities. These activities develop character, creativity, and positive social interaction, emotional balance & intelligence, as well as kinesthetic awareness.
You will learn:
Loved it. A great class for Kids!
Good value for the price. Best for beginners. As someone familiar with teaching yoga to adults, I had already figured out a lot of the adaptations on my own. However, it was nice to have the conclusions confirmed by the YogaFit Kids program. The children in the video seemed very natural and were great examples.
If you have taken any yoga courses, this will be really, really basic.
I think this course is something I could run as a clinic in my gym.
very informative and material is well written.
Well organized, thorough and fun!
Not the most professional writing, but in terms of delivering applicable ideas for yoga work with kids, it served its purpose. Thank you!
The material is easy to read and gives detailed information about how to structure a class and correctly execute and modify poses/games. Overall the material was good and better than basic.
Good course for home study especially.
I am currently teaching Kids Yoga and had read some books, knew the poses, but the age appropriateness and the structure of YogaFit Kids is worth the price and a wonderful .7 CEC's! Almost re-certified and its only been 4 months since I earned my certification. ACE MindBody CEC's through YogaFit are the most affordable and wonderfully educational for a home study guru such as my self. Thank you ACE and YogaFit for these amazing options!
How Would You Rate This Product Out of 5 Stars?
The American Council on Exercise reserves the right to discontinue the sale and/or support of any continuing education course at any time, in order to cancel, correct, or update content based on current industry standards, guidelines, and/or technological advances. Notification will be given 6 months prior to expiration to allow for course completion and no refund will be given for expiring courses.


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Published on August 4th, 2014 | by Jo Borrás
F1's Hybrid Tech Gives City Bus 20% More MPG
August 4th, 2014 by Jo Borrás
Originally published on GAS2
A new flywheel KERS system similar to those developed by Williams' Formula 1 team and used in the dominant Porsche/Audi endurance race teams is making its way to city buses – and it could mean a 20% improvement in fuel economy!
In April of this year, Williams sold the technology (and the team that developed it) to British automotive and aerospace conglomerate GKN. In the time since, the copmany has grown to a 55-man operation taht's working to get the Williams/GKN Hybrid Power system onto the mass market, so that English bus drivers can enjoy the added performance and efficiency that top-flight racing drivers have been enjoying for years.
What makes the flywheel hybrid system different from the systems used in the Prius, for example, is that it works completely without a battery. When the driver hits the brakes, a traction motor on the axle transfers the momentum of the vehicle to the flywheel, making it spin. The spinning flywheel then generates electricity while slowing the vehicle, augmenting the performance of the brakes and reducing wear. The flywheel operates in a vacuum to reduce friction, and can spin up to 36,000RPM. Once the driver gets on the gas, the system applies the momentum built up in the rapidly spinning flywheel to send as much as 120 kilowatts back the axles, helping acceleration and reducing the load demands on the internal combustion engine.
According to the video, above, GKN foresees the technology finding use in a variety of industrial applications, from elevators and commuter trains to (obviously) city buses. We'll keep you posted on their progress in the weeks and months to come.
GKN Hybrid Power Gyrodrive – Flywheel Hybrid
Source | Images: GKN, via Wired.
Check out our new 93-page EV report.
Join us for an upcoming Cleantech Revolution Tour conference!
Keep up to date with all the hottest cleantech news by subscribing to our (free) cleantech daily newsletter or weekly newsletter, or keep an eye on sector-specific news by getting our (also free) solar energy newsletter, electric vehicle newsletter, or wind energy newsletter.


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I found a pic on the internet images and made it into an appliqueOriginally Posted by kwiltkrazy
It was from a childrens coloring page. Easy way to find applique blocks.
Welcome to the Quilting Board!
I found a pic on the internet images and made it into an appliqueOriginally Posted by kwiltkrazy
It was from a childrens coloring page. Easy way to find applique blocks.
Just got my August block swap from Jetnica. Love the star love the colors. Just perfect :)
Also got an extra bonus. So be expecting something in the mail soon Jessica!
perfect block swap
Michelle -- please don't feel the need to send something extra. I'm happy the "suprises" are going to be loved at your house instead of collecting dust at mine!! =)Originally Posted by mstandridge
I'm excited! A two block swap sounds great!Originally Posted by Quilting Nonnie
I received my August Q.B. swap block, in today's mail the 30th, from Elly!! It is just beautiful & I really like it. Also, thank you Elly for the additional piece of flowered fabric. It's Great!! Enjoy everyone!!
My Log Cabin swap block from ELLY!!
How funny. Jessica, that is the exact block I'm doing for the winter block swap. I'm working on them now.
You don't have to do two--I'm just excited to use these two different fabrics I have!Originally Posted by bibliostone
Oooh, Sulabug, what a beautiful log cabin block - the softness of the colors is very restful. Nice!
Welcome to our new swappers!! You'll have so much fun here!
Sulabug I love your two tone log cabin block so pretty.
Was pleasantly surprised to open the mailbox tonight after work and found your block +! I will take a photo and post so everyone can see tomorrow --also will be getting your block out in the mail tomorrow I hope. Had my folks' 70th Wedding Anniversary plus full work weeks this past month so got behind. I'll let you know definitely tomorrow night if I made it to the post office. I like the fabric choices in this block you made --definitely reminds me of beach trips along 101 Scenic Route!Originally Posted by Pats8e8


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Free Camping
Trip Start Mar 07, 2011
71Trip End Aug 28, 2011
Map your own trip!
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Where I stayed
Spring Creek rest area
The scenery has been absolutely breathtaking, we agreed the three words most used since we left home were "look at that". From the beautiful beaches along the coast and now the ruggedness of the Kimberley, Australia is such a beautiful place.
We set up camp at a rest area at Spring River which is couple of hundred kms from Kununura. The camp is on the river. Had a fantastic night.There were about 20 vans free camping, including a couple from Scotland and a young guy from Germany. One of the guys set up a camp fire and we sat around having a drink and exchanging stories about our travels. It was so peaceful, no bloody green frogs, no mossies, just quietness.
After a great evening we settled in for a good sleep with the intention to leave before the cyclists catch up in the morning.


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Benefit Coverage While on Leave of Absence
Paying Paycheck Premiums
Costco pays the full cost of your health care benefits during your leave for a period of 90 days. If your leave exceeds 90 days, you must begin your regular benefit-related paycheck deductions to continue your health care coverage which includes medical, dental, pharmacy, prescription drug, vision and behavioral health. You are responsible for paying your regular benefit-related paycheck deductions regardless of whether you are on a personal medical leave (including pregnancy) or worker's compensation leave.
A notice and payment coupons will be mailed to your home after you have been on a Leave for 45 days. If you do not pay your premiums by the due date specified on the notice your coverage will terminate for non-payment and you may continue coverage under the provisions of COBRA. Click here to find out more about continuing coverage through COBRA.
Maximum Period Benefits Continue
If you were eligible at the beginning of your leave of absence (LOA) or became eligible during your LOA, your benefit coverage will remain in effect through the term of your approved LOA according to the following schedule and subject to premium payments mentioned above. The maximum period of time will be counted from the day your LOA begins.
|Length of Continuous Employment
|Maximum Period Benefits Continue
|Less than 90 days
|30 days
|Less than 12 months
|90 days
|12 months, but less than 5 years
|180 days
|5 years or more
|180 days
Continuing Coverage Through COBRA
If you are on an approved Costco Personal Medical Leave that extends beyond the maximum period of benefits listed above, and you elect to continue your COBRA health care coverage at your own expense, Costco will assist you with your monthly COBRA payments to continue your benefits according to the following schedule for a maximum of six months:
|Length of Continuous Employment
|Company COBRA Premium Susidy
|Less than 12 months
|No premium subsidy
|12 months, but less than 5 years
|25% premium subsidy
|5 years or more
|50% premium subsidy


text:
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Gaslight A newlywed fears... MORE > $14.36 Regularly $17.99 Buy Now
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Among The Best Ever
- James Smith
- 10/30/16
I fell for Ingrid Bergman hook, line and sinker. She is a compelling actress and beautiful woman. She owns me just as Audrey Hepburn did in Roman Holiday. Boyer performance is Award Award level and Cotton et al on target. Great Movie.
- Mark
- 3/11/16
This has got to be on the top 5 of my 'favorite movie list'. I often think about Bergman in this movie when thinking about a great 'classic' movie compared to the junk released so far in the 21st century. Ingrid Bergman at her best!
Love It More With Each Viewing
- donnadonna
- 2/27/16
My fav Jo Cotton role.Boyer totally evil,should've had a version with Basil Rathbone in the part.Once had a boyfriend who was a gaslighter,always trying to pull some type of fast one on me and always putting me down to his pals and family telling them I did what he actually did,not good things,either.Where's he know?Same place the Serge character is-his friends no where to help while he had a massive heart attack last year.They just threw his body in a cab to take him to hospital,but already too late.What got me was how blind Nancy and Elizabeth were to the hubby,he wasn't that charming!
Bergman Nails Best Actress Performance
- Delia
- 2/20/14
This is one of those movies that makes you wonder, "Why don't they make movies like this anymore?" It's got everything--a murder mystery, a duplicitous husband, a damsel in distress, a would-be suitor, and Bergman in the performance of a lifetime. Gaslight is the inspiration of all subsequent let's-scare-her-death movies and rightly so. Charles Boyer defines dastardly as the piano accompanist who courts and wins a gullible voice student (Bergman) in order to (spoiler alert) get closer to what he really wants--jewels. He develops a devious plan to drive Bergman insane with such malice that you want to jump into the picture and slap him. More than once. Bergman steps on the gas and never lets up as she's slowly driven to madness by her husband. Joseph Cotton is excellent as usual as the detective who senses something is amiss and a young Angela Lansbury is dandy as the catty housemaid who flirts with Boyer. The final scene with Bergman and Boyer in the attic is a tour de force from both players. As the Best Actress award went to Bergman that year, Oscar definitely got this one right. One of the true essentials.
- RedRain
- 6/9/13
Ingrid Bergman has never been better than she is in this very creepy film! I've been fascinated by the story for decades and watch this film whenever TCM schedules it. Charles Boyer, as the avaricious and evil husband trying to drive his wife insane, is also stellar in his role here. Watch Bergman's facial expressions and, in particular, her eyes as she begins to believe she's losing her mind. She says more with her face than any dialogue could match. Bergman was up against Bette Davis for her phenomenal performance in "Mr. Skeffington," Barbara Stanwyck for an equally good performance in "Double Indemnity," Greer Garson in "Mrs. Parkington," and Claudette Colbert in "Since You Went Away." There is no doubt whatsoever that Bergman deserved the Academy Award she won for this film!
A "must see" movie
- maureen v.v.
- 1/7/13
I wish it was in colour.It would have been wonderful to see all the costumes and jewels in technicolour. A good movie to watch. I gave the movie 4 stars mostly because of the suspense it had. The acting was only 3 stars.
A stunning film
- Pamela
- 8/29/12
I remember when I first saw this film. A friend had referred to my ex-husband's treatment of me as "gaslighting" and I had no idea what she was talking about. I looked for the film and when I saw it I understood just what she meant. Everything about this film is exquisite, from Ingrid Bergman, who is at the height of her earthy, sensual beauty, to the slippery Charles Boyer and our hero, Joseph Cotten (I can always watch a Joseph Cotten film). Yummy entertainment!
Incredible performace by all
- Kamster
- 6/19/12
One of the most involving flims I've seen due to the excellent performance by all the actors. This film introduced me to Joseph Cotten, who has now become one of my favorite actors. Beautifully filmed and masterfully directed. A joy to watch over and over again.
- Dashiell Barnes
- 2/4/12
A beautifully filmed psychological thriller. Bergman won an 'Oscar' among a great cast, giving one of her best performances. The costumes & art direction are visually appealing, however, the story has dated. A good film from Cukor. I give it a 4/5.
- MichaelTASO
- 2/4/12
this is old movie w/ actress i recognize!
Psycholgical, Dark and Sinister Remake.
- Frank Harris Horn
- 8/6/10
Charles Boyer, Ingrid Bergman and Joseph Cotten star in George Cukor's eerie, suspenseful remake of the original 1940 British film based on Patrick Hamilton's play set in Victorian London. Ingrid gives an Oscar-winning performance as a beautifully vulnerable newlywed, who is being driven insane by mysterious events making her believe she's losing her mind. Boyer is coolly sinister as her treacherous husband, who is trying to keep a terrible secret from her. The picture is rich in Victorian flavor, and fine performances remain intact. The movie also won a second Academy Award for Best Interior Decoration (B&W). With Angela Lansbury (in her film debut), Dame May Whitty, Barbara Everest, Edmond Breon, Halliwell Hobbs, Lawrence Grossmith, Heather Thatcher, Emil Rameau, Tom Stevenson & Terry Moore.
see the 1940 version
- herman
- 8/5/10
So she wins the oscar. I still think she's miscast. For me, Ingrid Bergman just radiates too much health and intelligence to be credible in this role. I think the 1940 British version is far superior. (They don't play it often, but keep a look out for it.)
Creepy and Romantic
- Cherie J
- 3/27/10
This is a classic title from the Golden Years of Hollywood and to my mind everything about it is perfect. The film's recreation of Victorian London is superbly realised all indoors at the MGM soundstages - it's all make believe but the viewer would never know it. Charles Boyer, who plays Ingrid Bergman's husband is suitably creepy and one is left wondering why he should be torturing such a beautiful creature. Ingrid Bergman is dressed to the nines in wonderful period costumes, and she is very sympathetic playing a dependent woman who is far stronger than she or the audience realises. This is excellent stuff and a film that is fun to watch over again if you are really devoted to some of these great old films.
gas light is classic
- david moro
- 10/31/09
i watched gaslight last night ohhh its mystery and a excellent cast
A Spellbinding Mind-Bender.
- Frank Harris Horn
- 10/25/09
Ingrid Bergman gives a well-deserved Oscar-winning performance in this remake of the original 1940 British film based on Patrick Hamilton's play set in Victorian London, in which she plays a young newlywed being driven out of her mind by a set of mysterious events. Charles Boyer is perfectly cast as her treacherous husband. The movie won another Oscar for it's magnificent Victorian England setting. Also starring Joseph Cotten, Dame May Whitty, Angela Lansbury, Barbara Everett, Edmond Breon, Halliwell Hobbs, Lawrence Grossmith, Heather Thatcher, Emil Rameau, Tom Stevenson & Terry Moore.
Gaslight (1944)
- Jay Higgins
- 8/19/09
Exquisitely acted, particularly by Ingrid Bergman and Angela Lansbury. The art direction is great and the score is very memorable. Excellent pace, atmosphere and very suspenseful.
Those were the days of great movies!
- Connie
- 1/4/09
I had seen this movie as a child and really did not appreciate it then. Today, I could not tear myself away from the TV. I usually feel it is an irresponsible use of time during the day to watch a movie BUT today was an exception. It is a classic and thank you for showing it.
Classic Movies are Classic for a Reason.
- Pam Lavoie
- 1/4/09
I really enjoyed this movie. Everything about it was very classy from the set to the plot to the costumes. It really proves a point not to second guess yourself, as that in itself is insanity.
One Of My favorite Bergman Films
- Barbara Lovejoy
- 3/14/08
Next to Indiscreet and Casablanca this movie is one of my favorite Bergman films. She really has you believing she is losing her mind and Boyer is superb as the villain.
Bergman is Brilliant
- Paula Donham
- 3/14/08
One of my alltime favorites. Bergman brings you right into the story, and Boyer is appropriately nasty as the scheming but handsome husband who stole her heart. Angela Lansbury is terrific as the insolent maid who seems to have designs on Boyer. Joseph Cotten is terrific as the sympathetic detective who rescues Paula. He is a hell of an actor. I watch this every time it's on and shared it with my kids; they like it, too!
- Danyelle
- 7/18/07
This movie is the start of me eatching old black and whites. I feel in love eoth this movie at first watch. Ms. Ingrid was something watch she is beautiful and a wonderful actress. One of the best everyone should watch in September.
this is good
- michael york
- 10/13/06
but the 1940 version is much better more atmospheric and tension-filled cukor and mgm make this one a little too glossy although boyer and bergman are great
- Valerie Arseneault
- 10/6/06
I saw this several years ago and never forgot it! Great to watch and own on DVD.I recommend it highly to all Ingrid Bergman fans especially
Your Overall Rating
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text:
This full website whois and analysis report on Gotomypc.eu was ran on May, 26, 2017.
Name: Corporation Service Company Website: www.incspot.com
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text:
Given we are nearing the halfway stage for the calendar year, I thought I would get in early with Aquasia's second-half credit outlook and comment on some interesting trends in Australian credit markets.
On February 3 2014, I wrote about the key trends that were likely in 2014. In summary, these were:
"Credit spreads have some potential to grind even tighter.
"There is always a potential that they will gap wider on any major market turmoil. If that were to occur, I would view it as a buying opportunity. Having said that, I believe that most investment grade companies operating in developed markets will see their credit spreads be relatively immune to the volatility."
At the start of the year, the rationale for tighter spreads was twofold: credit fundamentals were likely to remain stable and technicals were expected to be robust. Since then, other than tighter absolute spreads and lower yields, little has changed to alter that view.
Fundamentally, Moody's put the trailing 12-month global high-yield default rate at 2.4 per cent in April, and Moody's still expects it to fall to 2.3 per cent by the end of the year.
In terms of technicals, if anything these have become stronger – meaning a tendency for even tighter credit spreads. Government bond yields have defied predictions and have trended lower through the first half of 2014. As a result, yield-hungry investors have been forced down the credit spectrum.
Fixed income portfolio managers are still receiving, and expect to continue to receive, inflows and are essentially forced to put that to work in the asset class that many feel is very close to being fully valued.
In Australia, after the flurry of low investment grade-rated, true corporate new issues in the second half of 2013, and despite the demand from investors, issuance has slowed down considerably. What has continued to be a highlight is the plethora of unlisted, unrated corporate deals that have help to satiate the appetite of some yield hungry investors – both institutional and high net worth.
In addition, the first half of 2014 has also been notable because Australia saw its first rated high yield deals, with Qantas (BB+/Ba2) hitting the market twice in quick succession.
I expect there to be more higher yielding – rated or unrated – issuance in the second half of this year. Due to Basel III capital requirements, it makes sense for many banks to move corporate loans off their balance sheet and into the capital markets. In addition, given the current environment, it is natural that corporates should be seeking to extend maturity profiles and diversify funding sources.
So what is going to change the current status quo of the market?
There seems to be very little on the horizon. Furthermore, given the European Central Bank's decision to move the deposits rate into negative territory and with a good chance that Mario Draghi will perform its own magic with its version of QE, markets will continue to benefit from the methadone drip.
It is always a worry when markets and investors become complacent. There will be wobbles along the way – whether that be an escalation of tensions in Iraq and/or Ukraine, Europe, the US' slow growth, more concerns about China, its credit growth and potential property bust, or something new – but once again for most corporate credits the immediate future appears uninspiring.
For credit investors, dull and boring is good!
Recently I was speaking to an ex-boss of mine – the widely acclaimed distressed Queen – who is still swinging it at a US investment bank on Wall Street. It is fair to say she has been around a while and has been through more cycles than Cadel Evans; her opinion is always worth noting.
When I commented that spreads were tight but nothing was likely to change, she responded that the end of the credit cycle usually took longer than expected. As such, it could well be another 18-24 months before we really start to see the cracks appearing; at the moment the high yield refinancing wall is only building as a potential problem in 2016 and beyond.
In summary, the first half of the year saw the grind in credit spreads; the next part is likely to see the squeeze. While I agree that there is limited potential for further spread contraction, there is also a relatively low probability that credit fundamentals will see a material deterioration.
As investors continue to hunt for return, credit will remain in demand. However, credit investors should be happy to sit tight, clip the coupon and not forsake higher returns for uncompensated risks. But as one fund manager quipped: "The only exercise anyone gets these days is chasing yield."
Have a good week.
Mark Bayley is Credit Strategist at Aquasia, an independent corporate advisory partnership.
Any investment views, advice or recommendations contained in this publication constitutes general advice only and does not take into consideration any person's objectives, financial situation or needs. Furthermore, any investment views, advice or recommendations do not constitute legal, tax or accounting advice.
To the extent permitted by law, Aquasia Pty Ltd makes no warranties, and expressly disclaims any liability, in relation to the contents of this message.
The Australian Financial Review


text: Hey guys I'm pretty new to this forums but I need some help. I read through every post regarding the CEL code P0457(emissions evap. Fuel Cap loose). I have a 2004 WRX with a turbo back exhaust, and cobb accessport with stg 2 93 octane. I have checked the gas cap and seal, and then replaced both the cap and seal, checked the black box under the car and found no loose lines, checked the vacumm lines next to the alternator and no luck. My CEL will come on about 50 to 60 miles after a fill-up, and go off about a half a tank or just under. I don't top it off, I go just to when the nozzle kicks off the first time. I have tried to fill it to 3/4 of a tank and it still comes on and then goes off when its under a half a tank. I haven't had the fuel pump ever changed and I don't smell any sort of fuel fumes with the exception of during fueling of course. If anyone has any other ideas please help.


text:
Orioles Press Releases
Orioles roster move 5/26/17
This afternoon, the Orioles made the following roster move.
Orioles to auction Memorial Day gear to benefit Fort Meade Alliance Foundation
Throughout the Memorial Day holiday weekend, all Orioles uniformed personnel will wear ripstop woodland camouflage-designed jerseys and caps on the road and at home. The Memorial Day jerseys and caps will also feature five stars to represent the five branches of the military. The Orioles will wear a gray road version of the jersey on Saturday, May 27, and Sunday, May 28, while visiting the Houston Astros, and a home white version of the jersey on Monday, May 29, when they host the New York Yankees at 1:05 p.m. ET.
Orioles to host "Birdland Social" presented by GBMC Healthcare
The Orioles will host "Birdland Social," a Social Media Night event presented by GBMC HealthCare, on Tuesday, June 20, prior to the 7:05 p.m. game against the Cleveland Indians. The exclusive pregame party will take place on the center field Roof Deck with 250 of the Orioles' most engaged social media followers.
Orioles Roster moves: 5/22/17
This afternoon, the Orioles made the following roster moves: Reinstated RHP Gabriel Ynoa (pronounced ee-know-uh) from the 10-day disabled list (right hamstring strain) and optioned him to Triple-A Norfolk.
Orioles to Celebrate 25th Anniversary of Oriole Park with Events August 18 & 19
The Orioles today announced plans to celebrate the 25th anniversary season of Oriole Park at Camden Yards on Saturday, August 19, when the team hosts the Los Angeles Angels at 7:05 p.m. ET.
Honorary Bat Girl Contest Winner to Highlight Upcoming Homestand
The Orioles return on Friday, May 19, for a six-game homestand featuring a three-game, weekend series against the Toronto Blue Jays and a three-game series against the Minnesota Twins.
Chris, Jill Davis are race ambassadors for Casey Cares Foundation 5k Run/Walk
For the second consecutive year, Orioles first baseman CHRIS DAVIS and his wife, JILL, will serve as race ambassadors for the eighth annual Casey Cares 5K Run/Walk at Oriole Park at Camden Yards on Saturday, August 5, as the Orioles and OriolesREACH once again partner with the Casey Cares Foundation to host the race.
Orioles to Host 'Celebrate Maryland Day' on Saturday
The Orioles have announced plans to host 'Celebrate Maryland Day' at Oriole Park at Camden Yards on Saturday, May 20 when the team takes on the Toronto Blue Jays at 7:35 p.m. ET.
Orioles Roster Moves 5/10/17
This afternoon, the Orioles made the following roster moves.


text:
|Data Dictionary:
|Census 1970
you are here: choose a survey survey data set table details
Survey: Census 1970
|Data Source:
|Social Explorer & U.S. Census Bureau
Data set: Social Explorer Tables (SE)
|T131. Dishwasher (5%) [3]
Universe: Count of Occupied Units
Table Details
|Dishwasher (5%)
|Universe: Count of Occupied Units
Relevant Documentation:
|Excerpt from:
|Social Explorer; U.S. Census Bureau; 1970 Census Usersâ Guide; U. S. Government Printing Office, Washington, D. C., 1970.
|1970 Census Users' Guide - Part I -> Part Ill. Housing Census Concepts (Concepts 150 through 250) -> Household equipment* -> Dishwasher


text:
Top Terms
Ledger Pop Journal - Celebrity & Showbiz News
Miley Cyrus Caught with No Underwear - Anorexia and Eating Disorder Reports Hits, Too
Does Miley Cyrus have anorexia or an eating disorder?
And where are her underwear?
Miley Cyrus is really slender, the young star has slimmed down considerably and is being photographed frequently in tight outfits as she plays in and around Hollywood.
She is also furious that she is being called anorexic, but on April 8, Cyrus tweeted a photo of herself inhaling the contents of a Carl's Jr. takeout bag with just her nose to smell it and wrote, "I can't eat it. So I'm just gonna smell the shittttt out of it! My mouth is LITERALLY watering."
After comments on why she wouldn't eat it, Miley tried to clarify.
She tweeted the next day, "For everyone calling me anorexic I have a gluten and lactose allergy. It's not about weight it's about health. Gluten is crapppp anyway!"
Where are her panties?
In the wild days of Britney Spears, she was photographed around Los Angeles without her panties on several occasions and now Miley has been snapped without anything on under her short dress.
Is Miley flashing her goods?
After finishing Windsor Pilates in Los Angeles April 6, the 19-year-old starlet climbed into her car and gave photographers quite an eyeful of her private parts. Oops!
Check out the picture here.
No wedding anytime soon.
After several wedding rumors hit when Miley was showing off a huge ring on her wedding ring finger, Liam Hemsworth revealed he is way is too young to get married.
The 22-year-old Hollywood hunk and his 19-year-old girlfriend Miley were the subject of wedding rumors recently after the 'Hannah Montana' beauty stepped out wearing what appeared to be an engagement ring but Liam says he won't consider marriage for some time yet.
He told Britain's OK! magazine: "Marriage and kids are way in the future for me. I'm young. It's not really on my mind at the moment - marriage, kids or anything."
The 'Hunger Games' actor and Miley have been dating on and off since meeting on the set of 'The Last Song' in 2009.
(Image: WENN)
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text:
Reno 911 Visits TRL
Ah, the cast of "Reno 911″ on TRL. Police uniforms, tiny shorts, Ray-Ban sunglasses and firearms. The only thing glaringly absent from this picture is LaToya Jackson, but that may have something (or EVERYTHING) to do with my fascination with her.
Let's be honest, there's a time and a place for crotch shots (like NEVER) but all bets are off in the name of comedy. The high-kick Lt. Dangel executes is disturbing, albeit quite impressive. It's a testament to the high-quality of the fabric used on his shorts and for which a slightly terrified Katherine McPhee is more than a little thankful. And you know what? At least he's got the legs to pull it off.


text:
Note : Your Quotation Request will be directed to L-3 Narda-MITEQ.
The AMF-2F-16401710-15-5P from L-3 Narda-MITEQ is a RF Amplifier with Frequency 16400 to 17100 MHz, Gain 16 dB, Gain Flatness ± 1 dB, Noise Figure 1.5 dB, P1dB 5 dBm. Tags: Power Amplifier, Low Noise Amplifier. More details for AMF-2F-16401710-15-5P can be seen below.
You can now find similar products from multiple companies on everything RF.


text:
Large winter storm drops much needed moisture
Sunday's winter storm dropped a month's worth of February moisture in one day, the state climatology office reported.
The Minnesota Climatology office characterized the storm as a "large, lumbering winter storm" bringing badly needed precipitation to the state.
"Some impressive liquid totals were found as well with some areas receiving over an inch of liquid from this storm," the climatology office reported. "Normal February precipitation ranges from about a half inch in the northwest part of the state, to an inch in the far southeast."
This storm formed over Nebraska and Kansas before moving northeast. By Sunday, the snow storm's center was over south central Minnesota.
Blizzard warnings were issued across parts of western and southern Minnesota with a number of highways closed because of zero visibility and dangerous driving conditions.
The climatology office, a division of the Department of Natural Resources, reported the highest snowfall was in the west central city of Rothsay with 21 inches. Underwood, in Otter Tail County, reported 17 inches of snow. Bemidji and Itasca State Park received 16 inches of fresh powder. Twin Cities suburbs received about 3-4 inches. The Twin Cities had rain, sleet and snow with the storm getting a heavy wet snow Sunday. The Minneapolis-St. Paul International Airport reported 2.3 inches of snow.
Monday, the National Weather Service updated snow storm totals:
■ 11.8 inches Little Falls.
■ 11.5 inches Wadena.
■ 11.7 inches Deer Creek.
■ 9.5 inches Hillman.
■ 9 inches Motley.
■ 8.5 inches Fort Ripley.
■ 7.4 inches Long Prairie.
■ 7 inches Milaca.
■ 6.5 inches Brainerd.
■ 5.5 inches Aitkin.
Tuesday should provide a break from cloudy skies with the forecast calling for sun and a high near 29 degrees. Wednesday could be the warmest day of the week with a high flirting with 33 degrees. By Wednesday night, there could be more snow to shovel if the forecast for snow, mainly afternoon and at night, pans out. There is a 30 percent chance for snow Wednesday, growing to 40 percent Wednesday night. The chance for snow persists Thursday. The forecast calls for partly sunny days and temps in the mid-teens for the end of the week extending into the weekend. By Presidents Day, the chance for snow returns and the day should be warmer with a high near 25, providing an opportunity to enjoy the snow.
RENEE RICHARDSON, senior reporter, may be reached at 855-5852 or firstname.lastname@example.com. Follow on Twitter at www.twitter.com/Dispatchbizbuzz.


text:
ejector pump suddenly tripping gfi
OK, I'm an electrical dummy ...
I have finished basement w/a bathroom. We have an ejector pump off the bathroom that has been plugged into an outlet w/gfi since I've owned the house (10 years). There is also a booster fan for my electric dryer plugged into the outlet (has been the same for 10 years). The only thing that has ever tripped up that outlet is using a hair buzzer in another outlet within the bathroom (but once you hit the reset its fine).
This morning I realize the ejector pump was not sucking down the water from the drains. I looked at the outlet and realized it needed to be reset. When I reset it, the pump would run for a few seconds and the outlet would trip up again. Tried this a few times. Thought maybe it was an issue w/the outlet altogether. Neighbor suggested maybe it was an issue with the pump. Went thru various scenarios and bottom line is when I plug the pump into other outlets it works totally fine and once I do that and reset the outlet it was on, the booster fan works fine and the outlet does not trip. So, basically this outlet is tripping when the pump is on it but the pump is not tripping other outlets and the outlet works fine as long as the pump is not on it.
What could be causing this? Why would an outlet that housed the two things on it all of a sudden continue to trip when the pump is on it but the pump is fine on its own in another outlet and the outlet is fine on its own w/o the pump?
Replace the gfci receptacle, as they do go bad.
When you plug in the pump, are you using a gfci receptacle?
The pump could be bad also.
If it was bad, would other things work in it fine without tripping it up?
Yes, I've tried the pump in two other outlets and it is working fine (one of them being another GFI outlet), and it did not trip it up - only tripping up the original outlet.
try this: remove the suspected faulty GFCI, replace it with the other GFCI outlet that the pump worked in when you were testing and see how it goes. you may have an issue with the entire circuit of the 'original' GFCI receptacle but if it works with a different receptacle, it even more strongly suggests it is the GFCI receptacle that is the problem.
and like jbfan said, these do go bad from time to time.
limiting effect.
These are usually bad/loose/dirty connections somewhere.
With lite loads the effect is usually minimal,
But if a larger load tries to start up (motor)
then the losses become much larger,
possiblly stalling the motor.
remember motors require a large start up current
to get going.
Check all the connecttions,
right back to the panel if nessecary.
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