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National cyber defense competition is April 17-19
By Christi Fish
Public Affairs Specialist
(April 14, 2009)--Baker College in Flint, Mich., will defend its Alamo Cup title this weekend when it joins seven other teams in San Antonio at the National Collegiate Cyber Defense Competition (link to video) (NCCDC) April 17-19 at the Hilton San Antonio Airport hotel. The event is the fourth iteration of the nation's largest collegiate cyber security competition, which was created by and hosted by the Center for Infrastructure Assurance and Security (CIAS), a nationally recognized leader in cyber security education and training at UTSA.
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- La Prensa Foundation is newest member of UTSA Lone Star Society
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- USA Today: UTSA long jumper Tyler Williamson rescues three-year-old boy
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CIAS's NCCDC has grown from five participating schools in 2005 to more than 60 schools in 2009 with eight regional competitions nationwide, two more than in 2008.
The 2009 NCCDC competitors are:
- Baker College, Flint, Mich.: 2009 CCDC Midwest Regional winners and defending 2008 national champions
- Northeastern University: 2009 CCDC Northeast Regional winners
- Dakota State: 2009 CCDC North Central Regional winners
- University of North Carolina, Charlotte: 2009 CCDC Southeast Regional winners
- Texas A&M University: 2009 CCDC Southwest Regional winners
- Cal Poly Pomona: 2009 CCDC West Coast Regional winners
- University of Pittsburgh: 2009 CCDC MidAtlantic Regional winners
- University of Washington: 2009 CCDC Pacific Rim Regional winners
NCCDC is the first practical cyber security competition designed to test how students operate and manage a network infrastructure, similar to that found in the commercial sector. While similar to other cyber defense competitions, NCCDC is unique because it focuses on business operations and incorporates the operational aspect of managing and protecting an existing network infrastructure.
"The National Collegiate Cyber Defense Competition continues to grow from the single regional competition five years ago to the eight regional events and several state qualifiers this year," said Gregory White, director of CIAS and UTSA associate professor of computer science. "The feedback we get from both the faculty and students is phenomenal. Both are enthusiastic about the real-world training that the competition provides -- something that the students don't see in the normal academic lab. Sponsors have provided similar comments stating that traditionally they have been disappointed with the college graduates they get because they lack real experience. The graduates they pick up who have been involved in the competition, however, are better able to immediately make a difference for their company."
The event provides institutions with information assurance and computer security curricula an opportunity to assess their students' depth of understanding and competency in managing challenges in protecting a corporate network infrastructure and business information systems. CCDC events at the state, regional and national levels are designed to (1) build a meaningful mechanism by which institutions of higher education can evaluate their programs, (2) provide an educational venue in which students are able to apply theory and practical skills learned in class, (3) foster a spirit of teamwork, ethical behavior and effective communication within and across teams and (4) create interest and awareness among participating institutions and students.
The competition calls for student competitors to imagine themselves as new network and security administrators at a small company. At the start of the competition, each team inherits an "operational" network from a fictional business complete with e-mail, Web sites, data files and users. The competitors are given very little information about the company's network, its security levels and the software it uses before the competition.
However, they are given a few minutes to familiarize themselves with the new networks and systems, so they can begin installing security updates and patches before the red team starts actively scanning and probing their companies. In the midst of the commotion, competitors are required to keep up with the needs of their business and user demands while maintaining service level agreements for all critical Internet services.
Scoring is based on keeping required services up, controlling and preventing un-authorized access, and completing business tasks that are provided throughout the competition in the form of "injects." Teams accumulate points by successfully completing injects and maintaining services. Teams lose points by violating service level agreements, usage of recovery and restoration services, and successful penetrations by the Red Team.
At the end of the competition, the team with the highest score will be named the National Collegiate Cyber Defense Competition Champion and holder of the Alamo Cup title. After the competition, teams can talk with members of the Red Team to learn how the opponents carried out their attacks and how students could have defended their networks more effectively.
NCCDC is sponsored by a variety of San Antonio and national businesses in the information security, information technology, broadband and publishing industries. This year's major sponsors include Cisco Systems, Core Security Technologies, Microsoft, G-C Partners and Northrop Grumman. Donated hardware and software from leaders in the IT industry are used in the competition to provide students with opportunities to work with technologies they would never see in a typical classroom.
UTSA's CIAS is one of three components of the Institute for Cyber Security (ICS). The institute's other subunits include a research arm (ICS labs) and an incubation and commercialization arm (ICS Incubator). For more information on the cyber security competition, visit the National CCDC Web site or contact Greg White at (210) 458-2166 or Dwayne Williams at (210) 458-2173 at the UTSA Center for Infrastructure Assurance and Security.
Background: UTSA Center for Infrastructure Assurance and Security
- Established in 2001, CIAS leverages San Antonio's infrastructure assurance strengths and bolsters educational initiatives in the field. The multidisciplinary research center is a partnership between academia, the information technology security industry and the local Air Intelligence Agency. CIAS addresses the technical and policy issues of information assurance and security and provides educational training.
- In 2002-2003, CIAS led the highly successful Dark Screen cyber terrorism exercise for San Antonio bringing national attention as the first city in the nation to conduct a cyber security exercise.
- Since 2006, CIAS has been awarded more than $13.8 million through the Department of Defense and the Department of Homeland Security to fund community Cybersecurity Defend and Attack Exercises and Infrastructure Assurance and Security Research.
- CIAS personnel have conducted exercises for the various critical infrastructure information sharing and analysis centers as well as for states and communities around the nation
- In February 2008, CIAS personnel participated in the Department of Homeland Security's CyberStorm II National Cyber Security Exercise in Washington, D.C.
- UTSA was the first Texas university with the national "Center for Academic Excellence in Information Assurance Education" designation by the Department of Homeland Security and National Security Agency. The designation means UTSA's curriculum and faculty meet or exceed national standards to teach information-assurance security.


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With a tip of its wings to signal good-bye, the A350 XWB departed Singapore today for its Toulouse, France base of operations, completing a highly successful tour that began in Qatar and wrapped up with a starring appearance at the 2014 Singapore Airshow.
While at Singapore, this A350 XWB – the MSN3 developmental aircraft – literally made headlines as the jetliner was visited by airline customers, pilots, industry executives, the media and others, while also participating in the air show's daily flying display.
Its non-stop return flight to Toulouse of approximately 15 hours will add to more than 1,000 hours already logged by MSN3 and its sister MSN1 aircraft, which will joined soon by two more A350 XWBs, along with a fifth in May.
For this A350 XWB tour, we've been able to combine two goals: the continuation of flight testing, while also presenting the aircraft to the airlines and industry for the first time, said Patrick du Ché, the Head of Development Flight Tests at Airbus. We really enjoyed being at Singapore. And while we're sad to leave, all of us are ready to return home and continue the progress toward the A350 XWB's type certification and the startup of deliveries this year.
Before the aircraft was moved from its static display location at Changi Exhibition Centre, there was a final burst of activity as air show attendees lined up to go aboard. For many, this was the first time they visited a developmental aircraft, providing an opportunity to see the extensive flight test instrumentation and systems.
After being transferred to an active runway at the adjacent Changi Airport, the A350 XWB took off and provided its final salute to the 2014 Singapore Airshow before heading home.

subset: commoncrawl


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NYC Cozy 3-Bedroom Renovated Manhatan 41
Vendégek száma6
Hálószobák száma3
Méret800 láb²
Floor No.1
- Légkondicionálás
- Internet/WiFi
- Törölköző
- Zárható szoba
- Családi / Gyerek barát
- Konyha
- Gyermekágy
Accommodation summary
|Henry Street, 10002 New York, Egyesült Államok
|Ingatlan típusa
|Ingatlan azonosító
|Acceptance rate
|Response time
|A few hours
|Calendar updated
|A week ago
The apartment features 3 double bedrooms, the master bedroom has a large flat-screen TV. Guests can prepare meals in the fully equipped kitchen, which includes a coffee machine. The bathroom has a walk-in shower.
The surrounding area is busy with, with a wonderful selection of an excellent selection of bars, bakeries, delis and more on offer nearby. The famous Brooklyn Bridge is a 20-minute walk from the apartment.
East Broadway Subway Station is a 5-minute walk from the apartment. Times Square, and other world famous sights centred around Midtown Manhattan, can be reached in just 20 minutes using public transport.
HázirendPlease respect the neighbours and keep noise to a minimum at night.
Please treat the house as you would your own home.
|Weekly rate for up to 3 guests
|1529 €
|Ár >3 vendégre
|12 € /fő/éj extra
|Érkezés legkorábbi időpontja
|Check-in before
|Távozás legkésőbbi időpontja
|Lemondási feltétel
A házigazda egyéb ingatlanjainak értékelései
Good value for the money. More chinatown than little Italy. Friendly area. Clean apartment. Good contact with the owner.
Nice appartment, clean, lot of space. We've got the feeling this was not a private appartment, but commercial.
we were 3 girls that rent an appartment at 125 east 31 street and its not real the room is listening here. Anyway everything went smooth and the room was large. And bed is comfortable. And the wi-fi was good.
The tv was big but its lagging sometimes with the anthena. And its hard to find power jack at the bed! Only bad thing is that you will hear the sound from street and cars passby the street. Can be pretty annoying in the morning. But otherwise tis close to everything.
The host cancelled the booking, this review is automated.
It was wa bit difficult to arrive inside the apartment, maybe they should change the method... but once inside everithing was good, the apartmend and our room were clean! all rooms were occupied, but it was no problem with the bathroom.
The location in Little Italy is perfect, there are a few subway stations within walking distance.
I thought to meet john but the only contact was by mail or phone. :-)
We spent one week at the appartement. The room is small,but still ok. We were on tour most of the time, why its wasn't important for us. The room and the whole flat is clean. Mike was a very friendly host and helped us, if we needed any information about NY or anything else. We can recommend the appartement and its host.
We did not get a warm welcome! We called upon arrival, voicemail no calling back. After trying again we were given instructions to got to building and enter the appartment with a code. All communication with Lucy was by mail or text message. All other guest we met, got the same 'warm welcome'. We found that rather unpolite.
The room was nice and clean. We had to share kitchen, living room and bathroom with 3 other rooms. That was a bit of a ajustment but it was all well cleanend every other day by a nice lady. The location in Little Italy was perfect! Nice restaurants, shops and near great sights.
We would recommend the appartment but suggest to Lucy and John to be more hospitable.
Nice place, clean and located in the Little Italy, we have been there for 5 days with any problem at all. Lucy was so pleased with us. I recommend it!
First time in NYC. Perfect location! We were able to get around really well. Place is good overall for what we needed. Shower adjustment valves could use a bit of work, but there were 4 of us and everything else works and at a very good price in this area. Glad we picked this place.
Very well located at south Manhattan.
Super close to Metro line 6 Green.
A lot of space in side.
The shower was hard to find out the best way to use, but in the and worked well.
A good place to stay with friends.
- Minőségbiztosított szállás
- Minden házigazda hitelesítésre került telefonon keresztül
- Biztonságos fizetés SSL titkosításon keresztül


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as a Giant? Significance of the game aside.
This thread is designed to keep things positive. Short and sweet answers only please. Let's try not to argue about any of the selections.
Off the top of my head I would say that his game against Carolina last year was extremely impressive. So was the 49'er playoff game because of the pressure he was under. I'll give it more thought and post my answer soon.


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Teen Summer Reading Program
June 1st will be the first day to sign-up for the Teen Summer Reading Program! This program will be open to all teens that have finished grades 6-12. Registration for the program will be open the month of June.
To complete the Teen SRP you only need to read 500 pages. After you've reached 500 pages, you will get a book of your choice and the privilege to attend the awesome SRP party at the end of the program. Want the chance to win more prizes? For every 125 pages you read beyond your first 500, you will receive an entry for our raffle drawings of prizes like: gift cards, ear-buds, art supplies, outdoor gear, sharpies, a snow cone machine, and more!
For those of you that go above and beyond and read 8,000 pages or more, you will be entered into a seperate drawing for a chance to win one of two Kindle eReaders; including a KindleFire!
We will also offering programs throughout the summer just for Teens. Some of these programs include: The Un-Offical Hunger Games Survival and Zombie Apocalypse...more on that later. Also, for every program you attend throughout the summer, you will receive a 125 page entry.
Have questions or want to learn more? Visit or call the Teen Zone/Reference desk.
Written by Sarah MacNeillMy name is Sarah MacNeill. Your Co-head Teen Librarian for the Wells County Public Library. I am a fair-weather golfer who enjoys the great outdoors as well as getting lost in a great adventure novel. I am usually found somewhere around the Teen Zone/Reference desk or putting on an awesome Teen program. I do answer my e-mail though so feel free contact me at .
Read all posts written by Sarah MacNeill
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Venturi Air Cleaners - AIR CLEANER SPD7 XL CHR
- Exposed filter design that enhances airflow
- Backing plate promotes smooth airflow into carburetor/throttle body
- Built-in internal crank case breathers
- Contrast Cut finish starts with a polished venturi air cleaner faceplate that has been black anodized, then recut to open up the design
- Platinum Cut uses the same process as the Contrast Cut, but the recut areas are hand polished to a brilliant shine
- Black Ops features gloss black on top of contrasting textured black for outstanding durability and good looks
- Contrast Cut Black Ops, RSD's newest finish, features a Contrast Cut with a Black Ops finish
- Includes high-volume air filter
- All mounting hardware included
- Made in the U.S.A.
- MANUFACTURER'S NOTE: Not legal for street use on pollution controlled vehicles.
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- 4.0 lbs.
- Have a question? Get in touch with us
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- 920-423-3309Mon-Fri 9-5PM CST
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The Writing Center offers a variety of events each semester, including workshops, training, and conversations about writing and teaching.
Student Workshops and Training are detailed in myBucknell
Faculty Workshops and Discussions are detailed in myBucknell
The following links are virtual breadcrumbs marking the 27 most recent pages you have visited in Bucknell.edu. If you want to remember a specific page forever click the pin in the top right corner and we will be sure not to replace it. Close this message.


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Story highlights
- Berlin's past as an espionage hotspot has left the city with numerous spying-linked attractions
- The Stasi Museum features relics of East Berlin's obsession with monitoring its own people
- Other destinations include a tunnel dug to tap into communication lines, and an antenna tower
At the former headquarters of the East German secret police, cheerful American and British tourists scan maps and chatter as they file into the blocky concrete building once known as "the House of One Thousand Eyes."
In its heyday, the Ministry of State Security, or Stasi, was the all-powerful shadow government of the communist German Democratic Republic (GDR).
Behind a grim concrete screen molded into eye-shaped portholes, true believer Erich Mielke created the world's first surveillance state -- operating a network of agents and informers so vast it encompassed every school, factory, apartment block and bar in the country, according to Anna Funder, the author of "Stasiland: Stories from Behind the Berlin Wall."
Mielke's grim bureaucracy wasn't the only game in town, I discovered on a do-it-yourself tour of "the spy's Berlin."
Before the Berlin Wall came down in 1989, the unique position of West Berlin -- a walled outpost of freedom behind the Iron Curtain -- made the divided city the focus of Western and Soviet "tradecraft" for nearly 50 years, says Bernd Kostka, author of "Berlin: Capital of Spies."
"Only here in Berlin were the main protagonists of the Cold War living door to door," Kostka says.
Along with the House of One Thousand Eyes, now home to the Stasi Museum (Ruschestrasse 103, Haus 1, Berlin; +49 30 553 68 54), various sites around the city commemorate the capital's clandestine history -- even as revelations that the U.S. National Security Agency was until recently tapping Chancellor Angela Merkel's mobile phone prove that the tradition lives on.
Noir intrigue
There's a wealth of experiences here for the espionage buff.
On a rainy night at Checkpoint Charlie (Friedrichstrasse 43-45, Kreuzberg, Berlin), the most famous crossing point between East and West Berlin, it's just possible to imagine the noir intrigue of John Le Carre's "The Spy who Came in from the Cold" -- however much a tourist destination it becomes on a sunny afternoon.
Watching the incomparable movie version starring Richard Burton helps.
Featured in that masterpiece as well as countless other films, the crossing's main historical importance stems from the infamous "Checkpoint Charlie standoff," when a 1961 confrontation between Soviet and American tanks nearly sparked World War III.
Outside the Friedrichstrasse S-Bahnhof (Reichstagufer 17, Berlin-Mitte; +49 30 46777790) -- another Le Carre locale -- the Tranenpalast, or Palace of Tears, captures the atmosphere of paranoia more vividly.
Named for the tearful goodbyes of separated families, this station was once the official crossing point for West Germans visiting relatives in the GDR. (Le Carre's "Sasha" recounts the story of a surrender to border guards here in "Absolute Friends.")
Along with smuggled contraband and artifacts from "behind the Wall," the museum showcases an incredible exhibition of video interviews and documentary footage -- as well as the original signs and apparatus for the checkpoint searches and interviews.
On the outskirts of town, the American side of the spy story is on display at the Allied Museum (Clayallee 135, Berlin; +49 30 8181990) in Zehlendorf -- which houses seven meters of a 420-meter-long Allied forces spy tunnel dug under the Wall to tap East German telephone lines in 1953. (A story fictionalized in Ian McEwan's "The Innocent" and the later movie starring Anthony Hopkins.)
One of the most celebrated missions of the early Cold War, the tunnel was the largest and most expensive intelligence operation in Europe in the 1950s.
But it's hard to say who benefited from it most, says "Capital of Spies" author Kostka.
Though the tunnel allowed the Allies to intercept some 400,000 Soviet army telephone calls and countless telegraph messages before it was discovered in 1956, the Russians knew about it from the beginning, Kostka explains.
They kept that knowledge hidden from Berlin to protect their own man in the British government, MI6 case officer and double agent George Blake.
The eastern portion of the tunnel, long thought to be lost, was discovered by a man chopping wood in 2012.
'Bridge of spies'
Near the tunnel's original location, the Glienicke Brucke, or Bridge of Spies, (Bundestrasse 1, Berlin) between Wannsee in the West and Potsdam in the East, is perhaps the most famous espionage landmark in the city.
The border crossing designated for the exchange of captured spies, it was here that a KGB agent caught spying for the Russians in New York was traded for downed U-2 spy plane pilot Francis Gary Powers.
It's an attractive spot on the Havel River, but there's little more than a plaque to mark its significance, so it's best viewed today as a quick stop on a larger tour of Potsdam or other nearby sites.
At the Teufelsberg, or Devil's Mountain, a similar listening post -- this one an abandoned U.S. radar station and observation tower -- has been taken over by Berlin's ubiquitous graffiti artists.
A silent tour around the strange, white radomes -- weatherproof microwave antennae cases reminiscent of Disney's Epcot Center -- gives an eerie feeling in the age of the recent NSA disclosures from Edward Snowden.
Once a secretive military enclave, the full history of the complex won't be revealed until documents are declassified in 2022, but it's estimated more than 1,000 spies worked here throughout the Cold War, 24 hours a day, 365 days a year, as part of a surveillance network known as ECHELON.
For me, though, nothing captures the Cold War spy's world better than the hot and stuffy Stasi Museum, where the GDR spymaster's suite of offices and conference rooms have been preserved unchanged.
In these spartan chambers, banks of Bakelite telephones, steel desks and chunky typewriters evoke what renowned Nazi trial chronicler Hannah Arendt might have called "the bureaucracy of evil," had she written about East Germany rather than the Third Reich.
As the milky light reflects off the wood paneling, a shudder runs down my spine.


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Popular property highlights
Located in Gaslamp Quarter within a short walk of San Diego Convention Center, The Westin San Diego Gaslamp Quarter is within a mile (2 km) of other popular sights such as Petco Park. This 450-room, 4-star hotel has conveniences like a full-service spa, an outdoor pool, and a 24-hour fitness center. Near the airport, it's also near Balboa Park and San Diego Zoo.
Enjoy a bite to eat at the hotel's restaurant, or relax with a drink at the bar/lounge. Savor a meal from the comfort of your room with 24-hour room service, or get a quick energy boost at the coffee shop/café. For your convenience, breakfast is available for a fee each morning from 6:30 AM to 11 AM.
The Westin San Diego Gaslamp Quarter's 450 rooms are air-conditioned and provide refrigerators, coffee makers, and free newspapers. LED TVs come with cable channels, and guests can stay connected with WiFi and wired Internet. Pillowtop beds sport Egyptian cotton sheets and down comforters, and bathrooms offer hair dryers and free toiletries. Free local calls, free bottled water, and laptop-compatible safes are also available.
At The Westin San Diego Gaslamp Quarter, guests enjoy a full-service spa, an outdoor pool, and a 24-hour fitness center. Valet parking is available for USD 48.00 per day. The front desk has multilingual staff on hand 24/7 to help with dry cleaning/laundry, concierge services, and luggage storage. Other amenities at this spa hotel include a spa tub, free WiFi in public areas, and 19 meeting rooms.
Property features
- Walking distance to San Diego Convention Center
- Free WiFi in public areas
- Onsite dining
- Spa
The Westin San Diego Gaslamp Quarter
Hotel Amenities
Hotel Amenities
The Westin San Diego Gaslamp Quarter is within 3 miles of (4.8 kilometers) the airport and the San Diego Zoo. This smoke-free hotel houses an Italian restaurant with a coffee shop. Complimentary WiFi is available in the public areas. This hotel offers 19 conference rooms, the largest of which accommodates 1,200 guests. Hotel also provides wedding services.
Recreation and relaxation facilities include an outdoor pool and sundeck, indoor spa tub, and a 24-hour fitness center with cardio machines, weights, and headphones for music. Spa services, provided through Pure Body Spa, can be enjoyed in guestrooms or the on-site treatment room.
- Spa tub
- Outdoor pool
- Multilingual staff
- Bar/lounge
- Free newspapers in lobby
- Restaurant
- Coffee shop or café
- Gift shops or newsstand
- Conference space
- Total number of rooms - 450
- Number of floors - 16
- Spa treatment room(s)
- 24-hour front desk
- Valet parking (surcharge)
- Smoke-free property
- Concierge services
- Dry cleaning/laundry service
- 24-hour fitness facilities
- Full-service spa
- Computer station
- Free WiFi
- ATM/banking
- Terrace
- Luggage storage
- Conference space size (meters) - 3252
- Number of meeting rooms - 19
- Snack bar/deli
- Breakfast available (surcharge)
- Elevator/lift
- Express check-out
- Meeting rooms 19
- Porter/bellhop
- Year Built 1987
- Conference space size (feet) - 35000
- Number of buildings/towers - 1
- Spa services on site
- Television in common areas
- Wedding services
Family Friendly Amenities
- Family Hotel
- Outdoor pool
- Free Wi-Fi
- Snack bar/deli
- Refrigerator
- Cribs/infant beds (complimentary)
Available in all rooms: Wireless internet access ( USD 12.95 per night ), Wired internet access ( USD 12.95 per night )
Available in some public areas: Free WiFi
Valet parking (surcharge)
Room Amenities
The Westin San Diego Gaslamp Quarter offers 450 air-conditioned accommodations with laptop-compatible safes and complimentary newspapers. Pillowtop beds feature Egyptian cotton sheets, down comforters, and premium bedding. LED televisions come with premium cable channels. Refrigerators and coffee/tea makers are provided. Bathrooms include bathrobes, complimentary toiletries, and hair dryers.
In-room wired and wireless Internet access is available for a surcharge. Business-friendly amenities include desks and phones; free local calls are provided (restrictions may apply). Additionally, rooms include complimentary bottled water and irons/ironing boards. In-room massages and hypo-allergenic bedding can be requested. Housekeeping is provided daily.
- Premium TV channels
- Coffee/tea maker
- Hair dryer
- Room service (24 hours)
- Premium bedding
- Hypo-allergenic bedding available
- Bathrobes
- Air conditioning
- Free newspaper
- Iron/ironing board
- Free local calls
- Free bottled water
- In-room massage available
- Pillowtop mattress
- Phone
- Refrigerator
- WiFi (surcharge)
- Wired high-speed Internet access (surcharge)
- In-room climate control (air conditioning)
- Daily housekeeping
- Private bathroom
- Free toiletries
- Rollaway/extra beds (free)
- Free cribs/infant beds
- Connecting/adjoining rooms available
- Desk
- In-room safe (laptop compatible)
- Cable TV service
- Blackout drapes/curtains
- Down comforter
- Egyptian-cotton sheets
Where to Eat
Pinzimini - This restaurant featuring Italian inspired cuisine offers a wide selection of Tuscan style entrees, antipasti, pizza, and paninis. The Pinzimini San Diego Bar will be the new downtown San Diego favorite spot for cocktails, meetings and mingling.
Open from 11:30 AM to 1 AM.
Breakfast from 6:30 AM - 11 AM
Lunch from 11 AM - 1:30 PM
Dinner from 5 PM - 11 PM
Ingredients Grab 'n' Go - This new venue offers Starbucks® coffee and espresso beverages, pastries, cereals, yogurt parfaits, whole fruit, and juice for breakfast. For lunch there are pre-made sandwiches, salads, hot soup, assorted chips, and other snacks. Open daily from 6 AM to 5 PM.
Nearby Things to Do
The Westin Gaslamp Quarter San Diego offers an outdoor swimming pool, sundeck, and indoor spa tub. Guests have complimentary access to the fitness center, open 24 hours a day. Spa services, provided by the Wellness Spa, can be enjoyed in two on-site treatment rooms or in guestrooms.
Sailing, golf, bowling, and bicycle rentals can be found nearby.
The recreational activities listed below are available either on site or near the hotel; fees may apply.
- Windsurfing nearby
- Snorkeling nearby
- Hiking/biking trails nearby
- Kayaking nearby
- Surfing/boogie boarding nearby
- Water skiing nearby
- Parasailing nearby
- Golfing nearby
- Sailing nearby
- Bicycle rentals nearby
- Segway rental/tour nearby
Spa Services
The Pure Body Spa provides in-room or treatment room spa services including massage, scrubs, facials and waxing. An appointment can be booked through the concierge.
- Hot stone massage
- Deep tissue massage
- Swedish massage
- Reflexology
- Number of treatment rooms 1
- Couples treatment rooms
- Body scrubs
- Aromatherapy treatments
- Massages
- Body treatments
- Facial treatments
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
- Accessible bathroom
- In-room accessibility
- Roll-in shower
Hotel Policies
Check-in time starts at 3 PM
Check-in time ends at midnight
Special check-in instructions:
Check-out time is noon
Payment types
Children and extra beds
- Children are welcome.
- Kids stay free! Children 18 years old and younger stay free when using existing bedding.
- Free rollaway/extra beds!
- Free cribs (infant beds)!
- Pets stay free
- Dogs only
- 2 per room (up to 50 lb)
You need to know
Extra-person charges may apply and vary depending on property policy.
Government-issued photo identification and a credit card are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
Pets allowed (no fees)
- Business center/computer access
- Internet access
- Phone calls
- Additional inclusions
Optional extras
- Breakfast fee: USD 21.50 per person (approximately)
- Fee for in-room wireless Internet: USD 12.95 per night (rates may vary)
- Fee for in-room wired Internet: USD 12.95 per night (rates may vary)
- Valet parking fee: USD 48.00 per day (in/out privileges)
- A late check-out fee will be charged
Hotel Name
- Gaslamp Westin
- San Diego Gaslamp Westin
- San Diego Westin Gaslamp
- San Diego Westin Gaslamp Quarter
- Westin Gaslamp Quarter
- Westin Gaslamp Quarter Hotel
- Westin Gaslamp Quarter Hotel San Diego
- Westin Gaslamp San Diego
- Westin San Diego
- Westin San Diego Gaslamp Quarter
- Westin San Diego Gaslamp Quarter Hotel
- Westin Gaslamp Quarter, San Diego Hotel San Diego
We should mention
Reservations are required for massage services and spa treatments. Reservations can be made by contacting the hotel prior to arrival, using the contact information on the booking confirmation. Children 18 years old and younger stay free when occupying the parent or guardian's room, using existing bedding. The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.


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As provost of Ball State, Terry King oversees the university's seven academic colleges, among other responsibilities.
Before arriving at Ball State in August 2006, King served as dean of the College of Engineering at Kansas State—a college of 150 faculty members, eight academic departments and 32 academic programs at the undergraduate and graduate levels.
He began his professional career as a research engineer at Exxon Chemical Co. in Baton Rouge, La., in 1979 and progressed to senior engineer in 1981. In 1982, he joined the faculty at Iowa State as an assistant professor, becoming an associate professor in 1986 and a full professor in 1990. He then became chair of the Department of Chemical Engineering at Iowa State, a position he held until 1997.
He has taught all levels of chemical engineering, produced more than 150 peer-reviewed articles, book chapters and reports, given numerous technical/scientific talks around the world, and holds three patents.
Provost King received his bachelor's degree in chemical engineering from Iowa State University in 1975, and his doctorate in chemical engineering from the Massachusetts Institute of Technology in 1979.
Copyright © 2017 Ball State University 2000 W. University Ave. Muncie, IN 47306
800-382-8540 and 765-289-1241


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The 2010 Faculty and Staff Convocation is set for Monday, Aug. 9, beginning at 8 a.m. The annual event welcomes full-time faculty back from summer break and serves as a kickoff to a new academic year.
The theme of the event is "Building Success Together." A continental breakfast will be served prior to the "State of the College" address by PTC President Dan F. Bakke at 8:30 a.m.
Guest speaker Paul Vitale will deliver the keynote address. A native of Russellville, Arkansas, Paul is a successful author, motivational speaker and trainer. His stress on the importance of a positive attitude, a strong work ethic and other vital concepts, coupled with his energetic and enjoyable presentation style, have made Paul one of the most popular keynote speakers at hundreds of training conferences, seminars, conventions, meetings and universities.
The audience will also hear the inspirational success story of Pulaski Tech student Tony Daughtery as well as a presentation by the Arkansas Association of Women in Two-Year Colleges.
Lunch will be served at 12:15 p.m. Division meetings will take place from 1:15 - 3 p.m.
A variety of professional development opportunities will be provided during the remainder of the week. For details, click here.
Pulaski Technical College


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Slip And Fall Injuries
Full Video Transcript
Slip and fall injuries are incredibly common and can result in serious injuries. A land or business owner has the duty to exercise reasonable care to protect individuals who are invited on the premises from dangerous conditions. While the owner is not required to guarantee the safety of others, they are required to take certain reasonable precautions. The mere existence of a dangerous condition on the premises that may cause someone to slip, fall and injure themselves may not be enough to establish liability unless it would have been reasonable to have discovered the situation. Also, owners have the duty to exercise ordinary care in maintaining the premises and keeping them reasonably safe, so that injuries won't normally occur. If you have been injured in a slip and fall on someone else's property, consult with an experienced personal injury attorney, who will explain the law and your legal rights.
Additional Slip and Fall Videos
Search LawInfo's Slip and Fall Resources


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What's up at The Warehouse
Week of Jan. 31 – Feb. 7
Jan. 31, Feb. 1, 4–7: Open to students in 5th-12th grade from 3-6 p.m.
Saturday, Feb. 2: Open to students in 5th-12th grade from 7-10 p.m.
Monday, Feb. 4: Adult open gym basketball from 7-9 p.m., no cost or pre-registration required.
Wednesday, Feb. 6: Pine River Art Club beginning with a meeting at 10 a.m. followed by painting until 3 p.m.
The Warehouse is closed to students when PR-B School has a scheduled or unscheduled closing or early out. For scheduling events/meetings contact Sharon at 218-587-5404 during office hours (generally 2-6 p.m. on Monday-Friday). Check the Website at www.thewarehousepr.org for updates on events, closings and cancellations.


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Faculty Associate Research Grant Recipients Fall 2010 - Present
- Sylvie Beaudette, Eastman School of Music, Chamber Music
Beaufette received a grant to help cover costs related to her project "Unto Thee I Burn: Song Settings of e.e. cummings by North American Women Composers"
- Elena Bellina, Eastman School of Music, Humanities
Bellina's award covered costs to travel to the War and Life-Writing Conference at the University of Oxford to present "How I Saw a Corner of Africa; Life-Writing by Italian POWS in East Africa (1940-6)."
- Valeria Sinclair-Chapman, Department of Political Science
Sinclair-Chapman received a grant to cover travel costs to bring students from the Women of Color Circle and the Douglass Leadership House to the 2012 Seneca Falls Dialogues.
- Nancy Chin, Public Health Sciences
Chin was awarded funds for her research project "The Role of Gender in Community Trauma Recovery After a Natural Disaster."
- Ralph Locke, Eastman School of Music, Musicology
Funds were applied to Locke's participation in the joint meeting of the American Musicological Society, the Society for Music Theory, and the Society for Ethnomusicology in New Orleans, where he organized and chaired a session on Claude Debussy's songs written for soprano Marie-Blanch Vasnier
- Rachel Remmel, Eastman School of Music, Humanities
This award helped cover costs for Remmel to travel to the Symposium of the Association of Historians of American Art in Boston to present "Women Creating Art Infrastructure in the 1870s and 1880s: The founding of the Cincinnati Art Museum."
- Elena Belina, Eastman School of Music, Humanities
Award for research on "Gender and Cross-dressing Among Italian POW in British Camps in Africa (1941-1947)."
- Nancy Chin, Community and Preventive Medicine
Grant to cover costs for research of "Rapid Assessment of Tobacco Knowledge, Attitudes, and Practices in the Leh, India."
- Douglas Crimp, Department of Art and Art History
Funding for work on "Way Out on a Nut," a chapter from BEFORE PICTURES.
- Ralph Locke, Eastman School of Music, Musicology
Award granted for research on the project "Music and the Exotic Other, 1500-1800: Some Methodological Considerations and Case Studies."
- Jean Pedersen, Department of History
Pedersen's award will help cover expenses for her project "Imagining the Woman Worker: Politics, Philanthropy, and Fiction Under the Third Republic."
- A. Joan Saab, Art and Art History
Grant awarded for research on "Radical Craft: Exhibiting Homelands in Rochester, NY."
- Douglas Crimp, Art History
Received grant for research for project titled, "Our Kind of Movie: Essars on Andy Warhol's Films."
- Rachel Haidu
Traveled to Brussels to present her paper: "Le système des objets: film, feminism, and the domestication of the sign" at the French Theory: rèception dans les art visuels aux États-Unis entre 1965 et 1995 conference.
- Cilas Kemedjio, Modern Languages and Cultures, Frederick Douglass Institute for African and African-American Studies
Traveled to Université Laval, QC for his research project, "Maryse Condé and her Afro-centric Sisters: A Caribbean Reading of Afrocentricity."
- Stephanie Li, English
Traveled to present her paper, "The Gospel of Toni Morrison" at the Toni Morrison Society Conference held in Paris, France.
- Greta Niu, English
Traveled to present her paper "Video Games and Virtual Empire: Gender, Sexuality, and Asian Pacific America in The Guild" at the Association for Asian American Studies Annual Conference.


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Drummond to Serve as an Assistant Director of Athletics
BROWNWOOD, Texas - It was announced today by Howard Payne University Director of Athletics Mike Jones that Troy Drummond will now serve as the Assistant Director of Athletics for Operations along with his duties as HPU men's basketball coach.
"We are excited to promote Troy Drummond to the Assistant Director of Athletics for Operations," said Mike Jones HPU Director of Athletics. "He is a true servant and would do anything to help anyone. He has served our department in many ways and is well suited for this position. I am pleased that he has agreed to join my administrative team."
Troy Drummond will work with the Director of Athletics and all head coaches on facility needs for all home contests. He will assist in preparation of facilities for all home contests.
"I would like to thank Coach Jones, Dr. Ellis and Dr. Marsh for this exciting opportunity," said Troy Drummond. "I am grateful and looking forward to proudly serving Howard Payne University in this capacity. I feel it an honor to be a part HPU."
Troy will also assist in the organization of the annual HPU Sports Hall of Fame golf tournament and Sports Hall of Fame Banquet.
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Data longevity depends on both the storage medium and the ability to decipher the information
Kurt D. Bollacker
Given all of this varied advice, what can we do to save our personal digital data? First and foremost, make regular backup copies onto easily copied media (such as hard drives) and place these copies in different locations. Try reading documents, photos and other media whenever upgrading software or hardware, and convert them to new formats as needed. Lastly, if possible, print out highly important items and store them safely—there seems to be no getting away from occasionally reverting to this "outdated" media type. None of these steps will guarantee the data's survival, but not taking them almost guarantees that the data will be lost, sooner or later. This process does seem to involve a lot more effort than my grandparents went to when shoving photos into a shoebox in the attic decades ago, but perhaps this is one of the costs for the miracles of our digital age.
If all this seems like too much work, there is one last possibility. We could revert our digital data back to an analog form and use traditional media-preservation techniques. An extreme example of this is demonstrated by the Rosetta Project, a scholarly endeavor to preserve parallel texts of all of the world's written languages. The project has created a metal disk (right) on which miniaturized versions of more than 13,000 pages of text and images have been etched using techniques similar to computer-chip lithography. It is expected that this disk could last up to 2,000 years because, physically, the disk has more in common with a stone tablet than a modern hard drive. Although this approach should work for some important data, it is much more expensive to use in the short term than almost any practical digital solution and is less capable in some cases (for example, it's not good for audio or video). Perhaps it is better thought of as a cautionary example of what our future might look like if we are not able to make the digital world in which we find ourselves remain successful over time.
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Douchebags Articles
Annoying and entitled Hollywood celebrity douchebags.
James Franco's not a creep, just a victim of social media
Click here for a refresher on the time James Franco wanted to get a hotel room to share with a 17 year old girl called Lucy on social media. She posted their exchanges online which is when the whole world found out he's a gross pervy loser. Full Story
Celebrities and social media: James Franco edition
A 17 year old girl, soon to be 18, called Lucy, went to New York this week to pre-celebrate her milestone birthday. She went to see a few shows. At some point, after Of Mice & Men, she met James Franco. They took some pictures. She posted those pictures on social media, tagging him in some of the shots. Full Story
The Justin Bieber tapes
FameFlynet, Corbis/ Splash
I'm not sure it's a good idea for you to watch these on a Monday morning. I'm not sure it's a good idea to show you something that will make you violent on a Monday morning. So maybe don't watch if you have an important meeting coming up? Or a client lunch later on? Justin Bieber is infuriating at the best of times. Full Story
Robin's public appeals
Todd DC/ AKM-GSI/ Splash
Robin Thicke is behaving like a desperate man. As you know, he and Paula Patton announced their separation on Monday. Or, she announced their separation on Monday. Because he cancelled several tour stops to try and get her to change her mind. Which she hasn't…so far. And now he's taking his appeal public. Full Story
If you thought Shia LaBeouf's behavior in Berlin was the pinnacle of how weird he can get, guess what, you were wrong. Because now, immediately on the heels of whatever that was in Berlin, The Beef is back in Los Angeles, where he is doing something he claims is performance art but which I call stunting. Full Story
Shia LaBeouf is still a thief and a liar
Remember when Joaquin Phoenix lost his mind, grew a big bushy beard and said he was going to be a rapper? And everyone was like, "Whatever, weirdo," and laughed at him, and then he was all, Wait, wait, it's a joke! Then he made that "documentary" with Casey Affleck, I'm Still Here, and claimed it was meant as some kind of commentary on celebrity and popular culture. Full Story
Are Shia LaBeouf and Sean Penn related?
A couple of months ago in London, Shia LaBeouf got punched in the junk for being a dick. So, like, just a regular Tuesday. Sarah wrote about it here. According to the British papers, Shia was once again being a dick at a restaurant recently but this time, he was the one who told his opponent that: "I can get you killed. Full Story
Sean Penn goes Alec Baldwin
Justin Sullivan/ Getty
Sean Penn spoke at a business conference last night in San Francisco. Then he went for a drink at the hotel bar where a fan, someone who was at the conference, tried to creep a photo. At which point this happened: Unfortunately your browser does not support IFrames. Sean Penn FLIPS OUT on Fan -- 'I'll Make You Eat Your Cell Phone!' Full Story
Taking a sh-t on Justin Timberlake's face
Janette Pellegrini/ Kevin Mazur/ Getty
Those are his words, not mine. Justin Timberlake is one of five men featured in GQ's Men of the Year issue. And the interview happened just as critics were eviscerating his movie Runner, Runner and Part 2 of The 20/20 Experience. You remember, don't you? Variety's headline was "Why Justin Timberlake Should Stop Acting". Full Story
This is your future Shia LaBeouf
CARL COURT/ Gareth Cattermole/ Getty
Shia LaBeouf keeps getting into bar fights. You know who's also been known to drunkenly throw his fists around at a bar, or outside a bar? Josh Brolin. It's like they're father and son. Brolin was in Santa Monica the other night, getting messy with a bouncer after the establishment asked him to leave. Full Story
Robin Thicke like Justin Timberlake
Usually it's the other way around – JT sounds like RT, JT's sound is RT's sound, etc. This time, it's Robin Thicke doing the Justin Timberlake. Thicke's interview with Oprah Winfrey airs this weekend. PEOPLE.com Full Story


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In an effort to illustrate the sublime aestheticism of the Shimer classroom, I have essayed to capture some of the more salient moments of recent class discussions in that most ephemeral of poetic forms, the haiku. Feel free to contribute everybody. Also, to avoid in-joke snobbery in this public forum, the poet's comments will be provided if solicited.
From Soc1:
Fieldwork is so tedious…
Rely on Fortune.
Ego Projection,
Confirms this cosmic struggle.
Back offa my yams!
From Hum1:
Oh passionate Bach,
In was für Missetaten,
Bist du geraten?
And from IS2:
Like, ~[E ^ (~R)],
=>(~E) v R.
E=>R, man!
Where E ≡ Santa Claus has elves
and R ≡ Santa Claus has reindeer.
Santa Claus does not
Have no elves. The Reindeer sitch?
It's looking good.
(thank you Dorothy for this bit of unassailable logic).


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The Iowa Lakes Competitive Dance Team along with Head Coach Danie Juhl would like to announce the signing of Alexandra Kamstra of Orange City and Samantha Kollasch of Bancroft.
The Laker Dance team is coming off of excellent debut season where they placed first at the Iowa State Drill Team Association State Championship.
For more information about the dance team and other athletics at Iowa Lakes Community College, visit www.iowalakes.edu.
Alexandra Kamstra, Head Coach Danie Juhl, Samantha Kollasch


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Stylish Room with Breakfast (ST1)
Maksimum Konuk Sayısı2
Yatak odası1
Boyut14 metrekare
Floor No.
- Mutfak
- Çamaşır makinesi / Kurutma makinesi
- Kahvaltı
- Kilitlenebilir oda
- Havlu
- İnternet/Kablosuz ağ
- mevcut Otopark
Accommodation summary
|Gibraltar Walk, E2 7EN London, Büyük Britanya
|Mülkiyet türü
|Özel oda
|Referans kodu
|Acceptance rate
|Response time
|A few hours
|Calendar updated
Smart and sleek the private bedroom features a double bed, an office area and plenty of storage space. Guests are welcome to use the well-equipped kitchen complete with a breakfast bar and tiled bathroom.
Liverpool Street Train Station is just a 15-minute walk away, whilst the West End and Oxford Street can be reached within 20 minutes' journey by London Tube. Numerous 24-hour bus routes service central London.
The surrounding neighbourhood hosts a wide variety of bars, Indian restaurants and art galleries. For nightlife lovers, Shoreditch is one of London's prime clubbing destinations.
Ev kurallarıPlease clean up after yourselves.
|Check-in Saati (Sonrası)
|Check-in before
|Check-out Saati (Öncesi)
|İptal Koşulları
Bu mülk için yapılan yorumlar
The bedroom was nice, plenty of space and good bed. Maybe de pillows, could have been better, but they're ok for everyone. The shared bathroom and toilet, were clean and comfortable, also de kitchen where we've met nice people, and ate many times.
It was kind and good, I think I'd recommend it for friends and couples, it's well connected, you have the Liverpool St. Station just 10 minutes walking, and the Bethnal Tube in the oposite way, 10 minutes or less far away.
I'd liked being there.
Thanks for all!
Really good stay in this room. Kaz gives us by mail all the indication for collecting the keys on checkin day. Comfortable bed and nice kitchen to have breakfast. Hot water in the shower to that's all you need for your stay. Not far from Liverpool street tube and rail station. We suggest to get in the bus n.8 from brik lane to liverpool street and than thake the metro you desire!
Nice place, great value for money. The previous visitor broke the door lock when they moved out. I sent an email to the owner and within two hours it got fixed. Better don't leave much food in the fridge, one of the guests stole all my food when they moved out...
Nice stay in London. The apartment is very central and the room was omforable. When we understood that we could take bus 8 or 388 from Liverpool station to the house it saved us time and we could rest our feets for some minuts.
Location: 9/10
Facilities: 9/10
Located within just 10min walking from Liverpool Street Station in a quiet neighborhood.
Next convenience store just 50m away. Easy to find if you follow the well prepared instructions by Kazzos.
The flat is nice and neat. Wifi ok. Bathroom working but not high end.
Overall a place to recommend.
The room was large, very cozy and comfortable for us to stay despite of a light tobacco smell on the sheets.
The apartment was clean, nice kitchen but the bathroom needs some renovation.
The location is convenient next to bus stop or shoreditch station.
We didn't have the occasion to meet the host but he provided us all the information needed before arrival.
We enjoyed our stay and definitely recommend this place !
- Kalite güvenceli konaklama
- Her ev sahibi telefonla doğrulanmıştır
- SSL şifrelemesi ile güvenli ödeme


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POW veteran tells his story at recognition day ceremony
JACKSONVILLE, ONSLOW COUNTY - On the third Friday of every September, people across the United States honor the prisoners of war and missing-in-action service members from all of the nation's conflicts.
More than one hundred locals gathered at the Lejeune Memorial Gardens for National Prisoners of War and Missing in Action Recognition Day. The Onslow County Rolling Thunder, an organization dedicated to honoring those service members, hosted the ceremony.
Retired Chief Warrant Officer Guy Hunter was a POW for almost two months during Desert Storm.
"We had been up north of the Kuwait border running air strikes on some Iraqi divisions. When we went back up the second day, this time they were prepared for us," Hunter said.
According to Hunter, while on a recon flight mission in Kuwait in January 1991, his aircraft was struck down by a missile.
"Down we went in flames and landing in the middle of an Iraqi infantry division," Hunter said.
Hunter recalled he and several other POWs were held in an interrogation prison.
"They were pretty ruthless and vicious with everything they did," Hunter said. "They starved us essentially."
But Hunter said he never gave up hope, and then the day came when the war was over.
"Some civilian stood there in front of me and said in Iraqi, 'I can tell you this you're leaving today,'" Hunter said.
Hunter said he now speaks about his time held captive and teaches military members what to do if they ever find themselves in his position.
National Prisoners of War and Missing in Action Recognition Day is one of six days throughout the year Congress has mandated the flying of the National League of Families' POW and MIA flag.


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Amgen 386 for Recurrent Glioblastoma
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Primary Objectives
Cohort A ‐‐ monotherapy:
To determine the efficacy of AMG 386 in participants with recurrent glioblastoma (GBM) as measured by 6‐month progression‐free survival (PFS6)
Cohort B - combination therapy:
Phase I To determine the maximum tolerated dose of AMG 386 in combination with bevacizumab given at 10mg/kg every 2 weeks in participants with recurrent glioblastoma.
Phase II To determine the efficacy of AMG 386 plus bevacizumab in participants with recurrent glioblastoma (GBM) as measured by 6‐month progression‐free survival (PFS6).
Secondary Objectives:
To evaluate radiographic response in both cohort populations. To evaluate overall survival in both cohort populations. To assess time‐to‐progression in both cohort populations. To investigate the safety profile in both cohort populations.
Exploratory Objectives:
To evaluate expression of factors associated with tumor angiogenesis using a multiples cytokine assay among participants undergoing therapy with AMG 386 with response to therapy and development of resistance.
This is an open‐label Phase I/II study of AMG 386 monotherapy and AMG 386 in combination with bevacizumab. Two cohorts will accrue and will be assessed sequentially. Each cohort will enroll participants with recurrent GBM. Cohort A will assess recurrent GBM participants who receive AMG 386 monotherapy at 30 g/kg every week. (Cohort A initially accrued at a dose of 15mg/kg, but this was increased to 30 mg/kg every week following an amendment). Cohort B will assess recurrent GBM participants who receive weekly AMG 386 plus bi‐weekly bevacizumab (10mg/kg). Cohort B will start with a Phase I component to determine the MTD of AMG 386 that is safe when used in combination with bevacizumab. AMG 386 is administered intravenously, and, when used in combination with intravenous bevacizumab, will be administered first.
Patients will be required to come to the clinic weekly for study drug administration.
For study purposes, a cycle of therapy will be 4 weeks. Treatment will continue until either evidence of progressive disease, unacceptable toxicity, non‐compliance with study follow‐up, or withdrawal of consent.
The estimated rate of accrual is 60 participants per year. The estimated date of accrual completion is 1.5 years from study initiation. The estimated date of study completion will be approximately 12 months from enrollment of the last study participant.
Glioblastoma Multiforme
Drug: Amgen 386
Drug: Bevacizumab
Phase 1
Phase 2
|Study Type:
|Study Design:
|Allocation: Non-Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|Phase I/II Study of Amgen 386 With and Without Bevacizumab for Recurrent Glioblastoma
- Radiological response rates [ Time Frame: 6 month ]The primary outcome is 6 month progression-free survival. The primary basis for assessing efficacy will be the proportion of patients who survive 6 months without disease progression (PFS-6).
- Radiographic response and Median progression free survival and overall survival. [ Time Frame: 6 months ]Median progression free survival and overall survival. The primary measure of safety outcome will include a tabulation of all grade 2 or greater, treatment related toxicities.
|Estimated Enrollment:
|Study Start Date:
|December 2010
|Estimated Study Completion Date:
|December 2016
|Primary Completion Date:
|July 2015 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: Amgen 386
Cohort A will assess recurrent Glioblastoma Multiforme (GBM) patients who receive AMG 386 monotherapy at 30mg/kg every week. As of August 1, 2013, Cohort A was closed to new accrual following early interim analysis of first 10 participants enrolled on study. None of these patients had achieved stable disease or response at their initial evaluation after 1-2 months of study therapy. Therefore, study investigators and sponsor agreed that the level of single-agent anti-tumor activity associated with AMG386 for recurrent glioblastoma patients is most likely insufficient to satisfy the stopping rule for low efficacy outlined in Section 14.5 for Cohort A.
Drug: Amgen 386
For Cohort A, AMG 386 will be administered intravenously at 30 mg/kg every week.
For Cohort B Phase I, AMG 386 will be administered intravenously at beginning at starting dose level of 15 mg/kg every week.
For Cohort B Phase II, AMG 386 will be administered intravenously at the maximum tolerated dose determined in the Phase I portion of the study every week.
Experimental: Amgen 386 and Bevacizumab
Cohort B will assess recurrent Glioblastoma Multiforme(GBM) patients who receive AMG 386 plus bevacizumab. Because the maximum tolerated dose of this combination therapy has not yet been established, a 3x3 Phase I study was used to determine the maximum tolerated dose. As of June 6, 2014, the MTD was determined to be AMG386 30 mg/kg administered intravenously every week(dose level +1) in combination with bevacizumab at 10mg/kg administered intravenously every other week. As of July 25, 2014 the Cohort B, Phase II portion of the study was opened to accrual.
Drug: Amgen 386
Drug: Bevacizumab
For Cohort A, AMG 386 will be administered intravenously at 30 mg/kg every week.
For Cohort B Phase I, AMG 386 will be administered intravenously at beginning at starting dose level of 15 mg/kg every week.
For Cohort B Phase II, AMG 386 will be administered intravenously at the maximum tolerated dose determined in the Phase I portion of the study every week.
The dose of bevacizumab will be 10 mg/kg and will be administered intravenously every other week.
Other Name: Avastin
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria
- Signed informed consent approved by the Institutional Review Board prior to participant entry
- Age ≥ 18 years.
- Karnofsky ≥ 70%
- Participant must be able and willing to comply with study and/or follow‐up procedures Participants must have histologically confirmed diagnosis of GBM patients with either grade III or IV malignant glioma are eligible to the Phase I portion of the study) and radiographic evidence of recurrence or disease progression (defined as either a greater than 25% increase in the largest bidimensional product of enhancement, a new enhancing lesion, or significant increase in T2 FLAIR) following prior therapy (i.e. chemotherapy, XRT, other investigational therapies).
- No more than 2 prior episodes of progressive disease (patients with more than 2 prior episodes of progressive disease are eligible for the Cohort B, Phase I portion of this study)
- An interval of at least 4 weeks (to start of study agent) between prior surgical resection or one week from stereotactic biopsy
- An interval of at least 12 weeks (to start of study agent) from the end of prior radiotherapy unless there is a new area of enhancement consistent with recurrent tumor outside of the radiation field, or there is histological confirmation of unequivocal tumor progression
- From the projected start of scheduled study treatment, the following time periods must have relapsed: 4 weeks (or 5 half lives, whichever is shorter) from any investigational agent, 4 weeks (or 5 half lives, whichever is shorter) from cytotoxic therapy (except 23 days for temozolomide and 6 weeks from nitrosoureas), 6 weeks from antibodies (or 5 half lives, whichever is shorter), or 4 weeks (or 5 half lives, whichever is shorter) from other anti‐tumor therapies.
- Participants must have recovered to a grade 0 or 1 from the toxic effects of prior therapy (with the exception of lymphopenia, which is common after therapy with temozolomide, and alopecia).
- No evidence of hemorrhage on the baseline MRI or CT scan other than those that are ≤ grade 1 and either post‐operative or stable on at least two consecutive scans. Clinical Labs - performed within 14 days prior to enrollment
- Hematocrit ≥ 29%, ANC ≥ 1,000 cells/μl, platelets ≥ 100,000 cells/μl ;
- Serum creatinine ≤ 1.5 mg/dl, serum SGOT and bilirubin ≤ 1.5 times upper limit of normal;
- PTT or aPTT ≤ 1.5 times upper limit of normal and INR ≤ 1.5
- Calculated creatinine clearance ≥ 40 mL/min according to the Cockcroft‐Gault formula OR per 24 hour urine collection
- Urinary protein quantitative value of < 30 mg/dL in urinalysis or <1+ on dipstick, unless quantitative protein is < 1000 mg in a 24 hour urine sample;
- Participants of child‐bearing potential who have not undergone a bilateral salpingo‐oophorectomy and are sexually active must consent to use an accepted and highly effective non‐hormonal method of contraception (i.e. double barrier method [e.g., condom plus diaphragm]) from signing the informed consent through 6 months after last dose of study drug.
Exclusion Criteria:
- Prior anti‐angiogenic therapy targeting VEGF or VEGF receptor including prior bevacizumab.
- Prior AMG 386 therapy or other molecules that inhibit the angiopoietins or Tie2 receptor.
- Co-medication that may interfere with study results; e.g. immunosuppressive agents other than corticosteroids.
- Active infection requiring intravenous antibiotics
- Current or within 30 days prior to enrollment treatment with immune modulators such as systemic cyclosporine and tacrolimus.
- Current us of warfarin sodium or any other Coumadin‐derivative anticoagulant. Participant must be off Coumadin‐derivative anticoagulants for at least seven days prior to starting study drug. ow molecular weight heparin is allowed.
- Current, recent (within 4 weeks of the first infusion of this study), or planned participation in an experimental drug study other than supportive care or epidemiologic studies.
- Herbal preparations/medications are not allowed throughout the study. These herbal medications include, but are not limited to: St. John's wort, Kava, ephedra (ma huang), gingko biloba, dehydroepiandrosterone (DHEA), yohimbe, saw palmetto, ginseng. Participants should stop using any herbal medications 7 days prior to first dose of study drug.
- History of clinically significant bleeding within 6 months of enrollment
- History of allergic reactions to bacterially produced proteins
- Known hypersensitivity to any component of bevacizumab (cohort B only)
- Known sensitivity to any of the products to be administered during dosing
- History of venous or arterial thromboembolism within 12 months prior to enrollment.
- Severe hepatic insufficiency (ongoing grade 3 or greater hepatic adverse events) or known active chronic hepatitis.
- Inadequately controlled hypertension (defined as systolic blood pressure >140 and/or diastolic blood pressure > 90 mmHg). The use of anti‐hypertensive medications to control hypertension is permitted.
- Any prior history of hypertensive crisis or hypertensive encephalopathy
- Clinically significant cardiovascular disease within 12 months prior to enrollment, including myocardial infarction, unstable angina, grade 2 or greater peripheral vascular disease, cerebrovascular accident, transient ischemic attack, congestive heart failure, or arrhythmias not controlled by outpatient medication, percutaneous transluminal coronary angioplasty/stent.
- Evidence of bleeding diathesis or coagulopathy
- Major surgical procedure, open biopsy, or significant traumatic injury within 28 days prior to study enrollment or anticipation of need for major surgical procedure during the course of the study
- Core biopsy or other minor surgical procedure, excluding placement of a vascular access device, within 7 days prior to study enrollment.
- History of abdominal fistula, gastrointestinal perforation, or intra-abdominal abscess within 6 months prior to study enrollment.
- Serious, non‐healing wound, ulcer (including gastrointestinal), or bone fracture.
- Any condition which in the investigator's opinion makes the subject unsuitable for study participation.
- Pregnant (positive pregnancy test) or lactating. Refusal or inability to use highly effective means of contraception (men and women) in participants of child‐bearing potential.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01290263
|United States, California
|University of California Los Angeles
|Los Angeles, California, United States, 90095
|United States, Massachusetts
|Massachusetts General Hosptial
|Boston, Massachusetts, United States, 02114
|Dana-Farber Cancer Institute
|Boston, Massachusetts, United States, 02115
|University of Massachusetts, Worcester
|Worcester, Massachusetts, United States
|United States, New York
|New York - Presbyterian/Columbia University Medical Center
|New York, New York, United States, 10032
|United States, Virginia
|University of Virginia
|Charlottesville, Virginia, United States, 22908
|Principal Investigator:
|David Reardon, MD
|Dana-Farber Cancer Institute
|Responsible Party:
|David Reardon, MD, Principal Investigator, Dana-Farber Cancer Institute
|ClinicalTrials.gov Identifier:
|NCT01290263 History of Changes
|Other Study ID Numbers:
|Study First Received:
|January 9, 2011
|Last Updated:
|April 5, 2016
Keywords provided by Dana-Farber Cancer Institute:
Brain Tumor
Additional relevant MeSH terms:
Neoplasms, Neuroepithelial
Neuroectodermal Tumors
Neoplasms, Germ Cell and Embryonal
Neoplasms by Histologic Type
Neoplasms, Glandular and Epithelial
Neoplasms, Nerve Tissue
Angiogenesis Inhibitors
Angiogenesis Modulating Agents
Growth Substances
Physiological Effects of Drugs
Growth Inhibitors
Antineoplastic Agents
ClinicalTrials.gov processed this record on May 24, 2017


text:
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text:
Kim T.
A MyFoodDiary Success Story
Name: Kim
What was the turning point that motivated your lifestyle change?
I had a gastric bypass about 25 years ago, and I lost 120 lbs. Over the years I started putting the weight back on. Last year, when I saw my twin sister (she also struggles with her weight), I knew I was headed right back to being obese. I had to put the break on. I had tried other programs, but I was not successful.
How did MyFoodDiary.com help in your weight loss journey?
I knew I needed to be accountable and keep track of my food intake. It made it so much easier tracking my food and weight. Since I lost the weight, I still keep track of what I eat, and my husband and I step on the scale every week to keep tabs on where we are and what we need to do.
Describe your new, healthy lifestyle?
I exercise more (walking and stretching), and I lead an active lifestyle. We go to Florida in the winter months and there I am able to swim an hour a day. I am able to do more, and I want to do more since I have lost the weight.
At the grocery store a few months ago, my husband asked me to hold 3 bags of dog food and I wondered why. He said, "That is what you lost. Now you know what you have been carrying around!"
What has been your biggest challenge, and how have you overcome it?
Finding lower calorie foods that also taste good, and staying within my calorie budget. I know for success I have to watch my serving sizes. I love fresh fruits and vegetables, but I would eat a whole watermelon and not think it was bad, never looking at the calories I was consuming.
What is one new healthy habit you didn't expect to like, but you now love?
Keeping track of the foods I eat, and staying within the 1200 calories allotted. My new food habit I find easy to do is measuring out the food I am allowed. I don't graze, and once I eat what is allowed, I am done.
What has been the greatest reward of your weight loss success?
The ability to wear all the new (old) clothes! That fact that I want to go for a walk, and that I don't just think about it.
What is your best advice for others?
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Anyone tried Maple?
I've googled a few recipes and haven't come across my experiment yet.
I started a 5 gal batch with 13 lbs of clover honey, pack of energizer and the remainder is about 25 brix maple sap...( sap 1/2 boiled down to syrup), 1122 yeast.
I didn't take a OG reading, mostly because i started the batch at 2 1/2 gallons because i didn't have enough sap and didn't want my sap to spoil. Later got some sap from a local syrup maker to top up.
Any predictions on how it will taste?
I'm sure it's going to have a maple flavor, just a Qn of how much. Most of my meads i use about 16 lbs of honey , the unknown is how much equivilant suger was in 5 gal of 25 brix syrup?
Any takers to figure that one out?


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AMD PCNET Family Ethernet Adapter/ISA+ (Legacy Mode) card (and some other adapters from other manufacturers compatible wit this device), but the HP PC LAN Adapter NC/16 TP (2100/1500T Compatible) card uses the same chip as AMD's cards and it's not on the list, so I tried it, and it worked like a charm. Just follow the info that comes with the driver, and it will work for shure ;)
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text:
Fun topic, although a very subjective one. Not the "86 team, not even close" conclusion that some would have us believe.
Some here confuse "best Giants team" with best Giants season, in my view. Understandable, since it can be argued that each season produces a unique team, but that's just one way to look at the question.
When the subject of the Niners of the 80s, for example, or the Steelers, Cowboys, Dolphins, Raiders of the 70s, is raised, it inevitably is discussed in terms of a team's general dominance during a sequence of several seasons, not just 1 season. I mean, do we really hear arguments about "the 81 Niners were their best team, not the 89 Niners"? No. Nearly every discussion concerning the Niners dominant years involve useage of "the Walsh Niners" or the Montana Niners". It is a legitimate way to approach this thread's title question, as well.
In that context, there is a compelling argument to be made for the Giants teams of the late 50s, early 60s as the "best Giants team".
During an 8 year stretch of 1956-63, Giants played in 6 Championship games. They won only 1 of those, true, but how many teams in the history of the league can boast that consistency over that many years? It is an elite club, to be sure.
With at least 5 HOF players on some of, if not all 6 of, the Giants teams in that stretch (Gifford, Huff, Rosey Brown, YA, Robustelli), plus the likes of Alex Webster, Charlie Conerly, Grier, Rote, Morrison, and with Landry-Lombardi doing the actual coaching of the first 2-3 championship teams, I submit there's a strong case to be made for that time frame as the "best Giants team, all time"
If you want to restrict the debate to only the Super Bowl era, then sure, we are restricted to a much narrower time frame of a single season here and there.
And even in that context there are different qualifiers in each of our Super Bowl-winning seasons that make this a very subjective argument---
86 team was arguably the most dominant team that year. However, even in the comparison of 86 to 90, it could be argued the 90 team was a better team overall, since 2 crucial players (Jumbo Elliott and Carl Banks) missed 8 and 7 games, respectively, due to injuries, and Simms missed the last 2 and a half games of the reg season and all the post season. We won the last 2 reg season games, 2 post season games and the Super Bowl with a professional back up QB, who was an average QB at best.
That could not have been accomplished unless the team was very, very good.
So, while there is no question the 86 Giants finished the second half of the regular season by steam-rolling through the competition with 10-11 consecutive wins, and they crushed their opponents throughout the post season culminating in a dominant second half of their Super Bowl victory, I'd say what the players and coaches achieved on the 90 team (they were absolutely dominant the first 10 games of that season, remember) after Simms went down for the season in Game 14, was even more impressive--defeating a very dominant Niners team intent on being the first (only) team to win 3 consecutive SBs, in the NFC Championship game, and defeating the most explosive team in NFL history up to that point, in the Super Bowl.
(Anyone who claims they actually believed the Giants hopes for a second SB trophy were not completely crushed when Simms broke his leg in that Dec '90 Buffalo game...is not being honest)
'86, '90, '07, '11 in that order.
If I had to guess I would say that you are to young to have witnessed the Parcells era. If you saw that defense you would never make the argument that the QB is the deciding factor of which team is the best.
The 86 team might of been the best, but I'll tell you what, the last team they would of wanted to see in the superbowl would be one of these recent Giants teams.
No sir the team with the best qb is the best team in history of the team if you won the sb.. i'd say the pats best years were with brady.. our best years with eli.. packers best years with rodgers.. colts best years with peyton.. broncos best years with elway (or maybe peyton now if they win sb) and ravens best years with flacco if they win the big one.. i can go on n on.
So a team that dominates all of football going 14-2 and winning the SB like 1986, is not as good as the team that went 9-7 and won the SB like 2011, solely because Eli is better than Simms?? Is that what you are saying??
Wow just wow!


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10:30 22nd October 2013
Jackett targets long haul
Kenny Jackett is advising his Wolves players not to become too fixated by League positions as they aim to return to winning ways at Molineux tonight.
Following the Johnstone's Paint Trophy exit against Notts County on penalties and Saturday's exciting derby draw against Coventry City, Wolves will be eager to sign off their run of seven home games out of nine by taking maximum points against Oldham Athletic.
Such has been the form of Leyton Orient and Peterborough United that a place in the top two is beyond the side for now but a return of 26 points from the first 11 League One matches is very much a record befitting serious promotion-chasers.
"I'm more one for looking at points totals at this stage rather than positions," the head coach said. "That's until about February. You try to see if you're on course.
"It's a fantastic start by Peterborough and Orient and the positive thing for us is that we're in touching distance of them.
"Some other big clubs are a significant amount of points behind already and we know we still have it in our hands as to where we finish.
"We're pleased with our points total. Have we got things to improve on? Yes, but we are well placed in a division that is stretching very quickly.
"The top two have a high points total but our focus is on what we do and on our own parameters.
"It is down to ourselves to put in the type of run where we can be consistently winning at this level to try to achieve our aim of getting promoted this year."
As Lee Johnson arrives at Molineux with an Oldham side who have won their last two games since drawing at home to Orient, Peterborough face Sheffield United at London Road while Orient go to Coventry.
The top three are all in action again on Saturday, with Wolves at Bradford City, but a possible 18-day gap between League fixtures looms for us in the middle of next month.
Following our rearranged Bonfire Night trip to Carlisle, the first round of the FA Cup accounts for the following weekend, then our scheduled trip to Notts County seven days later could be called off because of the next round of international fixtures.
That would explain why Jackett, rather than setting points targets for the season, says he is in the habit of 'ring-fencing' batches of fixtures, the latest of which is the one which ends with the Carlisle game.
His selection options for tonight's game are not affected by any fresh injuries, and Jack Price, withdrawn in the first half on Saturday, has recovered from the problem which forced him off.
And Jackett does not feel he necessarily needs any extensive changes due to the spell of fixtures.
"It was a migraine type problem with Jack Price that gave him a headache and blurred vision," he says.
"It didn't clear up and within the timeframe of the first half he decided he'd have to come off.
"With a headache and blurred vision we weren't quite sure what it was but it has cleared up in the last couple of days so he's ok.
"It's one of those things and I think he did have it once a couple of years ago but he's fine now.
"Can our players go again? I don't see why not as it is very early in the season and players should love playing.
"If I'm looking at internationals I think Matt Doherty played one out of the two, McCarey our sub keeper played two out of two and Doyle played two.
"Out of the starting eleven there are not many that have played too many games in this early stage.
"And from Saturday I would expect the recovery to be there and them to be fine for tonight's game."
*Tickets will not be available on the turnstiles tonight but they will be available from the Ticket Office. Supporters who purchased tickets for the Coventry game remain eligible to purchase a half price ticket for tonight providing it is with the same Supporter Number.
Gareth Prosser on debuts and development
2 days ago
Wolves will travel to Austria for their 2017/18 pre-season trainin....
4 days ago
News on out-of-contract players
7 days ago
Leicester City to visit Molineux
15 May 2017
Winger scoops quartet of awards
10 May 2017
Backroom staff storm to victory
09 May 2017


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Publisher: MGame USA, Inc.Developer: MGame Corporation and Netgame.Category: Massively MultiplayerWebsite: http://www.legendofares.comRelease: 6/15/06 scheduledCurrent Status: Open Beta
The Legend of Ares is 3D medieval fantasy-action MMORPG which revolves around the conflicts between two nations, The Holy Empire and the Religious Alliance. With distinctive quests, this game emphasizes the intense battle system, guild plays and warfare system.
Player vs. Player
Honor System: When a player kills another player from a rival nation or guild, they will receive one honor point. When a player is defeated by another player from the rival nation, one honor point is taken away. When a player accumulates a certain number of honor points, he/she will receive a rank within their nation's standing. The general rule of rank is: the higher rank a player achieves the greater the bonus that player will get towards his attack and defense power (see Ranking System on website). National War: Fight players from your rival nation to increase your ability through rank and honor points! While players will begin their journey in "safe" zones, there will be areas of the map later in the game where both nations must venture. Players should be on their guard when in these areas! Guild War: Player-created guilds will help players to level, hunt, and quest; but that's not all. Guilds will be able to wage war against each other regardless of nation-association, and can even band together to form alliances against their enemies. Alliance vs. Alliance and/or Guild vs. Guild warfare will be another way for players to achieve rank and honor points. Territorial War: There will be organized Nation vs. Nation events where players of each nation will fight for control of areas of the map. Each area will have their respective bonuses to bestow on the winning side in addition to increasing the size of the player's nation. In this way, players will have a direct impact on their nation's prosperity as well as an impact in the progression of the story. Needless to say, Territorial War will be a great way for players to gain rank through honor points.


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Closing the Deal the Old Fashioned Way
Lisa Lampanelli's guide to the postdate touchdown.
I know that you, my loyal Playboy readers, think of me as an old married beyotch, but that wasn't always my status. When I was a young single beyotch, my dating life was more active than Ann Coulter's thyroid. While I don't miss them in the least, I remember those times well. I especially enjoyed that point in a relationship when I was ready to go all the way, prepared to throw down the old dirty-dirty for the first time as a couple. For me, this was sometimes the third or fourth date in. Other times, it was the third or fourth drink in. And if the lucky guy supersized my meal, well, let's just say he could definitely count on boarding the train to Poontown by the time the check arrived.
Guys, it's pretty simple. If she's into you, it's like you're the U.S. Olympic basketball team and she's the Nigerian team: It's not going to be hard to shoot and score. Even if the path to a woman's vagina is as confusing as her Facebook time line, when she's willing and able to do the deed, only you can cock-block yourself. So here are some helpful tips to guide you on your journey to the place between her thighs.
Let's start with the basics. Preparation for a night of new nookie should begin with the big H, and by that I mean hygiene. Before going to meet up with your sweetie, take a nice hot shower, scrub, soak, floss, shave, pluck, exfoliate, sandblast—whatever you need to do. You don't have to be the best-looking guy or the smartest or the wealthiest. But if you smell vaguely like an onion stuffed with Limburger cheese spritzed with Axe body spray, you'll be touching yourself more than a third-base coach with chicken pox.
They say clothes make the man. Clothes can also make that man make a woman. So if you're dating a normal girl, there are a few fashion choices to avoid. These include Crocs, dreadlocks, ascots, argyle socks, suspenders, jackets with epaulets, capes, thongs, spats, knickers, Hello Kitty fanny packs, monocles, stovepipe hats and hand-knitted mittens. And while you're at it, leave your Darth Vader helmet at home.
So now you're ready to get your girl and begin your special night. To help you in your Indiana Jones–like trek to the ark of your lady friend's covenant, follow the three rules of real estate: location, location, location. A seven-course meal is going to stuff her (and not in the good way), an amusement park will exhaust her too much to take a ride on your Tilt-a-Whirl, and if the movie you watch together is sad, forget about it. Your crying at the end of The Notebook is not an aphrodisiac—that sappy ending will cost you a happy ending.
Wherever you end up taking her, keep the boozing to a minimum. You need to avoid the most dreaded social disease of all: whiskey dick. Nothing ruins a first time like your going from Peter North to Peter South in 30 seconds flat.
Okay, now you look good, you smell good, you've treated her to a magical night on the town. But wait! Where do you plan on bringing her to consummate this union? Your place? If the answer is yes, you'd better do some cleaning in that hellhole of yours—and by "cleaning" I don't mean spraying Febreze and making sure the toilet's flushed. You've got to make that place look more like a scene from inside The Bachelor's house and less like a crime scene from Law & Order: SVU. I don't care how cute and charming you are, she's not going to stay in your bed if she feels a half-eaten pizza crust wedged between her butt cheeks. On the other hand, don't clean up so much that it looks premeditated. If she walks into a dimly lit bedroom with mood music already playing and a bottle of champagne chilling, she's going to feel as if she walked onto the set of Extreme Makeover: Desperate-to-Get-Laid Edition.
Once she's in and she's comfortable, the next step is to grab her and throw her onto the bed, right? Wrong. Slow down, Mike Tyson! Patience is a virtue. No woman, no matter how horny, wants a guy to attack her like Kobe Bryant in a Cialis factory. It's your first time together. Make it last. Chances are you're both nervous, and even the slightest bit of aggression could have her blowing her rape whistle like an over-bribed NBA referee.
While you're at it, keep the chatter, especially dirty talk, to a minimum. Even worse than saying something overly sexual is saying something downright stupid. Some women may actually forgive you for channeling your inner Ron Jeremy, but saying idiotic things like "Nice rack! Who's your surgeon?" or "What's the matter, don't you own a razor?" or "Hey, I'm a Republican" doesn't work for anybody.
As for me, when I was dating, it all came down to one word: romance. Candlelit dinners, flowers, soft music. Does that make me cheesy? Sure it does. Remember, guys: Women are like pizza—cheese works well on both of them. Make a woman feel that being alone with her is more important to you than beating your buddy in Call of Duty, and your call of duty will be to her bedroom—every night.


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|GTA V Latest News | #GTAV | #GTAOnline
2005 MTA: SA Media Update
GTA: San Andreas - Community News | @ 06:41 PM MDT | By rappo
The Multi Theft Auto: San Andreas team have updated their website with some screenshots from the latest build (b10) of the beta MTA: SA. It's cool watching their progress, and the release seems to be fairly close. Another post at the blog today says that they are hoping the QA team will update the blog sometime soon going over testing procedures and revealing some more screenshots. Stay tuned for that update.
Until then, check out the rest of the screenshots and the new article at the official MTA Developer's Blog. Big thanks to Nite for the news.
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I have two hives, one that's just made it through its second winter. Last week I inspected it and found no queen, no brood, and no eggs. I saw a queen cell about half its completed size.
I inspected yesterday to see what was new. I saw a larva in the queen cell and it looked to be just about capped.
My second hive is a caught swarm whose queen has only in the past week started producing eggs and brood. I checked last week and was concerned I'd need to requeen her, but this week things are going well. But there's not enough eggs/brood to share with the other hive. Only two frames have eggs/brood, though the laying pattern is solid.
I fed both hives honey I harvested last fall that we haven't eaten yet since they were both on the light side.
My concerns are these:
1. I saw no drones. It's not supposed to rise about the 50's here. Is it possible she'll mate? Am I right in assuming it'll be another week and a half before she emerges and a week or so after that before she starts laying? There's no telling what the weather will be until then.
2. They're packing in pollen and nectar, but I'm worried about the population.
Thoughts? Experience?


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Waterfront Romance on Camano Island
Camano Island Waterfront Inn • Camano Island, WA
Escape Kit
- A Two-Night Stay for Two in a Room with a Hot Tub, Sundays through Thursdays between May 15 and June 30, 2013, or Any Days of the Week between October 1 and December 31, 2013
- Daily Breakfast for Two
- $25 Spa Credit
- Bottle of Washington Wine
The Destinations
Washington's best-kept secret? That would have to be Camano Island, about an hour from both Seattle and the Canadian border. While magazines and newspapers fawn over the San Juans, this oft-overlooked isle in the Puget Sound sits quietly as eagles soar overhead, whales breach offshore, and the Olympic Mountains hover in the background. And while it's mostly peace and quiet here, a few locally owned restaurants, pubs, and boutiques chime in when culture calls. Best of all? Camano Island is accessible by car, no ferry required, making it the perfect place for a placid reprieve from the city.
The Digs
Hot tubs, water views, fireplaces, the sound of waves crashing against the shore—these are just a few of the perks you'll encounter during your stay at Camano Island Inn. Elegant yet unpretentious, with rooms that feature plush featherbeds and original artwork (not to mention heated tile floors in the bathroom), this romantic waterfront getaway is more than just a bed and breakfast. With a full-service spa offering a variety of natural treatments, and a restaurant that sources much of its produce from its own organic farm, Camano Island Inn is really a destination unto itself.
Start each day with a breakfast of eggs Benedict or French toast, fresh pastries, fruit, hash browns, and toast. You'll have the option of dining by the fireplace in the dining room, under the covered deck overlooking the Saratoga Passage, or in your room.
The Diversions
• Sea Stone Spa & Beauty Bar
• Camano Island Bistro
• Camano Island State Park
• Canopy Tours Northwest
"Reserve one of nine guestrooms at the recently updated Camano Island Inn, where king-size beds, jetted tubs, and a very fine restaurant compete with the omnipresent views for attention."-- Seattle Magazine
escapes 30-day promise
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the fine print
- Vouchers may not be combined to extend stay
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- Vouchers include Daily Breakfast for Two, $25 Spa Credit, and Bottle of Washington Wine
- Other conditions apply • PAID AND PROMOTIONAL VALUES EXPIRES ON December 31, 2013 • PAID VALUE DOES NOT EXPIRE • PAID VALUE EXPIRES ON December 31, 2018 • PROMOTIONAL VALUE EXPIRES ON December 31, 2013 • Enjoy By December 31, 2013
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