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forum: Food & Drink
Pages: 1 | Home » Food & Drink » Need to replace my food processor and it's got to be a good one!
#1 Sat 06 Oct 12 10:16pm
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Need to replace my food processor and it's got to be a good one!
Previously I had a bog standard �70 or less Kenwood Food Processor. Acquired over 3 years ago it's now frustrating me. Trying to do pastes in the big bowl ends up with vegetables stuck to the sides, the liquidizer now barely works at all probably due to being incapable of crushing ice properly and I'm jealous of Jamie always having effortless times with his one 30 Min Meals! :P
I kid you not, I did his Asian Salmon meal and when I came to do the slurry, the blades wouldn't even chop that! It's rubbish! :-)
I now want to chuck that away (or give it to a mate) and acquire something brand new, modern, high tech and powerful. It needs to do the following things however:
(1) Crush Ice without breaking to pieces
(2) Have a powerful motor
(3) Have accessories such as a decent juicer and whisk bowl.
(4) Ideally have be a multi processor (i.e. food processor AND a blender/liquidizer).
(5) Make smoothies, pastes, slurries etc without leaving vegetables whole and unchopped stuck to sides!
What do you all use and can anyone reccomend a decent model that literally does everything well!? Price isn't an issue, but let's say �250 max for now.
#2 Sun 07 Oct 12 6:05am
- Forum super champ Occupation avoiding housework
- From The land of song.
- Member since Tue 04 Oct 05
Re: Need to replace my food processor and it's got to be a good one!
The food processor that Mr Oliver uses on his 30 minute meal show series is a Magimix 5200 .
(I have the same machine and rely on it for daily kitchen help. )
There are smaller versions avalible and I did notice in the Which report that one of the Magimix foodprocessor's was one of their best-buy recommendations.
I have bought 3 of my now adult children a Magimix for their flats/ apartments , a smaller model than I have but equally as efficient.
The Magimix processor bowl and lid can go in the to rack of a dishwasher.
I have never crushed ice in my Magimix as I have a kitchenAid blender and that has an ice crushing setting.
I have used Magimix food processors for over 25 years and the only reason we changed to a larger model was when the family grew ! Older Magimix was passed on to someone who would use it and it still works .
My sister had a kenwood food processor that I bought for my father around 25 years ago , he used it loads ,it had been on offer at the time and greatly reduced then the price got slashed again as the supermarket I bought it from was no longer going to stock foodprocessors and was half the offer price !
It was cheap .. Really cheap !
This good processor ended up with my sister after my father died . She has used it most days since. It was only this year that it broke down .
(I was amazed that it had still been in use !)
It was not possible to repair .
#3 Sun 07 Oct 12 12:29pm
- Forum champ Occupation Opiskelija
- From Finland
- Member since Thu 26 Aug 10
Re: Need to replace my food processor and it's got to be a good one!
I too have a magimix, and I love it. It seems to cope with pretty much everything. Mine came with a large bowl, mini-bowl, and citrus press, as well as various blades and an egg white whisk. I think you will always find some stuff sticks to the sides a bit, but I haven't found this too much of a problem. I'm afraid I don't know how well it crushes ice, as the ice maker on my fridge does that at the press of a button.
#4 Sun 07 Oct 12 2:16pm
- Forum champ
- From Newcastle, NSW, Australia
- Member since Thu 23 Oct 08
Re: Need to replace my food processor and it's got to be a good one!
I gave my old brawn food processor to my eldest daughter, it is about 25 years old and still works brilliantly. Separate processor and blender bowls and still does everything as well as when it was bought.
Replaced it with a kitchen aid stand mixer, permanently set up on the bench, a stick mixer with various attachments and pull the really old Phillips blender (30yrs old) out of the cupboard whenever it is needed which is rarely as the stick mixer does most jobs, is powerful enough and easily cleaned.
Not exactly the way you were thinking but maybe something a little different to consider.
#5 Tue 09 Oct 12 12:43am
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- Member since Tue 25 Jan 11
Re: Need to replace my food processor and it's got to be a good one!
Well I looked up the Magimix site. I saw their food processor, juicer and blender. Now I know that Jamie uses both the blender and the food processor and the reviews on Amazon seem to complement both highly. Although I've noticed the Duronic blender is far cheaper and also gets rave reviews. Bear in mind IT MUST BE ABLE TO CRUSH ICE WITHOUT BREAKING! I wish I had a fridge that did it for me, but until my Banners Broker business kicks off I won't be moving out of my flat any time soon! :-)
Food processor shows the 3200, 4200 and 5200 options as well as XL versions of each. I live by myself but do entertain for guests on frequent occasions. So maybe a 5200 is overkill and I should opt for the 4200 to get the best of both worlds...........XL required or not?
I wouldn't mind a juicer - vegetable/fruit smoothies would be useful to me in my abs diet. However the Magimix juicer gets horrible reviews and it's dam expensive. People tend to like the Phillips Juicer for �70-�80 on Amazon - gets a great deal of 5 star reviews.
Would I need all 3 though or can one of the appliances do an effective job of the other? I don't mind too much as I've got some money spare after cancelling my stock ISA!
Last edited by farmergiles (Tue 09 Oct 12 12:55am)
#6 Tue 09 Oct 12 6:56am
- Forum super champ Occupation avoiding housework
- From The land of song.
- Member since Tue 04 Oct 05
Re: Need to replace my food processor and it's got to be a good one!
The kitchenaid blender has a ice crushing setting so the motor alters to the task . It's a good machine and I know that around 5 years ago I purchased 2 for the school I work at. They make and sell smoothies to the children once a week and apart from having to change the rubber coupling once they have been very reliable , very much up to the task of coaling with frozen fruit ice etc.
they were expensive at the time when we bought them but have been great machines. We bought them originally as part if a 'healthy eating week ' project . During that week every child in the school had the chance to design a smoothie recipe and make the smoothie.
They also get used for when the children make soup and are good at blending soup ( yes you guessed there is a soup setting on the blender as well !) .
Pages: 1 | Home » Food & Drink » Need to replace my food processor and it's got to be a good one!


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Notice: On March 31, it was announced that Statalist is moving from an email list to a forum. The old list will shut down on April 23, and its replacement, statalist.org is already up and running.
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Re: st: Q on reg3 output for model fit
Jason R Franken <email@example.com>
Re: st: Q on reg3 output for model fit
Sun, 10 Feb 2013 11:47:41 -0600 (CST)
Thanks John,
By the way, when I tried -overid- after 3SLS, STATA returned the following error message
"overid works only after ivreg, ivreg2; use overidxt after xtivreg" ...
----- Original Message -----
From: "John Antonakis" <email@example.com>
To: email@example.com
Sent: Sunday, February 10, 2013 11:22:41 AM
Subject: Re: st: Q on reg3 output for model fit
OK...that chi-square is just a Wald test that the predictors
simultaneously = 0. It is not an overidentification statistic. You
should run that statistic in any case if you are overidentified by using
the userwritten command -overid- (available from SSC) to ensure that the
model constraints are tenable. After running reg3 just type -overid-.
Although a negative r-square is not necessarily a bad thing, it could
indicate misspecification, and the overidentification stat will catch that.
P.S. it is always good and saves everyone time if you post your output
so we are all on the same page.
John Antonakis
Professor of Organizational Behavior
Director, Ph.D. Program in Management
Faculty of Business and Economics
University of Lausanne
Internef #618
CH-1015 Lausanne-Dorigny
Tel ++41 (0)21 692-3438
Fax ++41 (0)21 692-3305
Associate Editor
The Leadership Quarterly
On 10.02.2013 17:58, Jason R Franken wrote:
> The chi-square statistic I'm talking about is posted to the right of R-square in 3SLS output from reg3 (or an F-statistic in the 2SLS version). I'm in doubt that it is the identification statistic described in the prior response to this post, since it is significant in text book examples with positive R-square at: http://www.ats.ucla.edu/stat/stata/examples/greene/greene16.htm.
> I thought this chi-square statistic is for the test of whether the model is no better better predictor of the dependent variable than its mean, but the negative R-squares I observe can occur when "ybar is a better predictor of y (in the sum-of-squares sense) than Xb" according to http://www.stata.com/support/faqs/statistics/two-stage-least-squares/. Hence, I shouldn't see a negative r-square when the chi-square test statistic rejects the null that ybar is as good as my model.
> I'm not sure what the chi-square statistic is testing ...
> Thanks again.
> Jason
> ----- Original Message -----
> From: "John Antonakis" <email@example.com>
> To: email@example.com
> Sent: Sunday, February 10, 2013 2:26:58 AM
> Subject: Re: st: Q on reg3 output for model fit
> I would worry more about the chi-square statistic of fit (i.e.,
> overidentification statistic, which is what I assume you are talking
> about). If that is significant, the model is misspecified and an
> unlikely candidate to have generated the data. So, I would rethink the
> model.
> Best,
> __________________________________________
> John Antonakis
> Professor of Organizational Behavior
> Director, Ph.D. Program in Management
> Faculty of Business and Economics
> University of Lausanne
> Internef #618
> CH-1015 Lausanne-Dorigny
> Switzerland
> Tel ++41 (0)21 692-3438
> Fax ++41 (0)21 692-3305
> http://www.hec.unil.ch/people/jantonakis
> Associate Editor
> The Leadership Quarterly
> __________________________________________
> On 10.02.2013 07:17, Jason R Franken wrote:
>> I'm running 3SLS using reg3 and get negative R-square (consistent with the explanation at http://www.stata.com/support/faqs/statistics/two-stage-least-squares/). As I understand, this can happen when the mean of the dependent variable is a better predictor than the model. However, the p-values of the chi-square statistic are significant. What if anything can I determine about model fit from the R-square and chi-square statistics in the output of reg3?
>> Thank you in advance for any insight you can provide.
>> Jason Franken
>> Jason Franken
>> Assistant Professor
>> School of Agriculture
>> Western Illinois University
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Escape Kit
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UTSA Honors College announces Terry Scholars
By Shelley Kilpatrick
Student Writer, College of Liberal and Fine Arts
(July 20, 2007)--The UTSA Honors College announced the second class of UTSA Terry Scholars has been chosen for Fall 2007. Terry Foundation scholarships are awarded to incoming freshman and offer each student up to $20,000 with the possibility of annual renewal up to four years. The scholarship covers the cost of tuition, fees, books, on-campus room and board, and miscellaneous expenses.
Today's headlines
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- UTSA alumna Jordan Kaufmann wins $50K for new stent-graft start-up
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- USA Today: UTSA long jumper Tyler Williamson rescues three-year-old boy
Article tools
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In the end, 14 students were awarded and accepted the scholarship to attend UTSA. In the new class, there are two high school valedictorians, six in the top 5 percent of their classes, and the group's average SAT score is 1,244.
The 14 freshmen and their areas of study are:
- Steven Castro, Taft High School, San Antonio -- Biology
- Freddy Cortes, L.W. Fox Technical High School, San Antonio -- Mathematics
- Chelsea Doria, James Madison, San Antonio -- Interdisciplinary Studies
- Fallyn Garcia, Bruni High School, Bruni -- Psychology
- Justin Holden, William Howard Taft High School, San Antonio -- Engineering
- Perry Mullins, Plano East Senior High School, Plano -- Biology
- Marissa Ramos, Foy H. Moody High School, Corpus Christi -- Biology
- Kaitlyn Schorr, Texas Academy of Math and Science, Denton -- Biology
- Enrique Segura, Pearsall High School, Pearsall -- Accounting
- Amanda Snell, Pharr San Juan Alamo High School, San Juan -- General Business
- Eli Solis, Robert E. Lee High School, San Antonio -- Civil Engineering
- Nadijah Tamimi, Kerr High School, Houston -- Biology
- Jasmine Tetley, Douglas MacArthur High School, San Antonio -- Biology
- Katherine Williams, Flatonia High School, Flatonia -- Biology
Howard L. Terry, a successful businessman in banking, construction, real estate and energy and his wife, Nancy M. Terry, created the Houston-based Terry Foundation in 1986. The program's goal is to make a lasting contribution to higher education in Texas. Rather than endow faculty chairs or fund buildings, the Terrys focus their philanthropy on supporting students who attend public colleges and universities.
UTSA is one of four public universities that host the Terry Foundation Scholarship Program, the largest private scholarship program in Texas. Other participating schools include University of Texas at Austin, Texas A&M University, University of Houston and Texas State University - San Marcos.


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i get my ass kicked if i fuck up, but i can still play a sword and board character and every dragon fight (as long as you're not using the broken marked for death, unofficial patch and skyre both fix it now) lasts a while
when the stars align and you spawn 4 dragons, it's pretty fucking intense, took me 2 hours to kill them. fight took place from riverwood up past the tower near the barrow and ended up by the lake
---------- Post added 2012-11-20 at 03:01 PM ----------
and if any of you are modders, learn to clean your mods with tes5edit. my mod list is full of the more popular/useful mods and i swear they're nearly all dirty. if each guy cleans his mod, it will be done better (you know exactly what you meant to do to your mod in the first place) and it's not easy cleaning 200 mods anyway
people are usually surprised how easy it is to do
---------- Post added 2012-11-20 at 03:05 PM ----------
thing is, your level mans jack shit anyway. 1-20 will go fast, 20-100 won't. world is leveling up around you and if anything, it makes the game a bit tougher if you cheese it to level and don't have the offensive ability to actually kill things around you.
i honestly wouldn't even bother with adjusting it, it doesn't really affect you


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College of Business Administration Sponsored Clubs
Accounting Club
In the fall of 2006, the College of Business Administration formed an OC Accounting Club. The club was organized to meet several times each semester to schedule guest speakers, to provide resources to the accounting faculty and to involve the accounting majors in greater leadership roles on campus. The first organizational meeting was held in November of 2006 and the Oklahoma Society of CPAs (OSCPA) spoke of their internship program and their student member program. For additional information, please contact Elaine Kelly or the Oklahoma Society of CPAs at www.oscpa.com.
American Marketing Association
The OC chapter of the American Marketing Association (AMA) was officially chartered in 2008 and has become a very successful organization in a short time. In the first years as a competitive chapter, the OC AMA has received national recognition at the AMA Collegiate Conference in 2009, 2010, 2011, 2013, and 2014, being selected from 140+ schools for demonstrating excellence in membership, community service, chapter planning and reporting. The conference is hosted by AMA International, the parent organization for collegiate chapters. Membership in the AMA brings many benefits to students such as the chance to network with marketing professionals who speak on campus at chapter meetings, the opportunity to develop leadership skills through officer positions or committee leadership, and membership in the Oklahoma City AMA chapter as well. For more information, please visit the website at www.amaoc.com, or contact faculty advisor Dr. Kerianne Roper.
Delta Mu Delta
Delta Mu Delta is the National Business Honor Society at Oklahoma Christian University. This organization is headed by Mickey Cowan, professor of Accounting. Students chosen for Delta Mu Delta are upperclassmen representing the top 20% of their class. When students are chosen for Delta Mu Delta, they become members for life.
Internships in the College of Business
The College of Business Administration assists in the sponsoring of many different internship programs for all majors in the field of business. Internships are available in accounting, finance, management, and marketing to improve the academic knowledge and hands on experience of all students. Internships are sponsored at Devon Energy Corporation, Chesapeake Energy Corporation, Grant Thornton, Visual Image Advertising, Funnel Design Group, and Economic Development Authority. In addition the Oklahoma Society of CPAs (OSCPA) sponsors an internship program for accounting and finance majors. For additional information on the OSCPA intern and scholarship program contact http://www.oscpa.com/


text:
Free personalized radio that
plays the music you love
Elaine Page
Her release schedule only became more frantic as the years went by: she put out albums almost yearly and performed in several huge productions for the British stage including Piaf, Anything Goes, and Sunset Boulevard. When Sunset Boulevard came to New York in 1996, it was her first time on Broadway. She was met with much critical admiration, and brought her considerable talents to a television special for the BBC called A South Bank Show. The special showed her visiting different parts of the world where her plays had been set, and performing songs there in character. It was soon after this that she was showered with awards from critic collectives, theatrical organizations, and even the Queen of England for her years of service to the British theater. She spent the second half of the '90s performing at many tribute and benefit concerts, as well as her first major non-singing role on the stage, The Misanthrope. Her recording schedule slowed down considerably after 1998. In 2000, she started on a successful run of The King and I and began work on a second duet album with Barbara Dickson. Next came a revival of the 1971 James Goldman and Stephen Sondheim musical Follies, with Paige playing the central role of Carlotta Campion. The cast recording for the musical appeared on CD late in 2011. ~ Bradley Torreano, Rovi
Selected Discography
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text: Well I finally got my S-10 fixed and running now, for the last month it has been driving excellent! arty: But it seems that a black cloud is following me around still, I am getting a loud clunking sound from the back of the truck. It is doing it every time I hit any size bump in the road, or when I make a fast turn and the truck shifts onto one side or the other. PLEASE tell me that a bad shock makes a clunking noise, I hope to hell it isn't the rear end again! I have had 3 rear ends put in this truck and it only has 54,000 miles on it, these are also the original factory shocks all the way around. I have 4 brand new Edelbrock IAS shocks for it that I bought about 3 years ago, because I got them for $50 each at Summit Racing's clearance sale. Problem is I don't feel like going out in the cold to change them, and no one will install them because I didn't buy them from them. NTB, Goodyear shop, and a few other places. Will it do more damage if I just keep driving it on a badly worn or broken shock, there is no visible broken shock mounts or broken welds. Although I am carrying 400lbs. of sand in it right now, no I can't take the sand out because the truck is 2wd. and is horrible in snow with no weight in the bed. Thanks for any suggestions of what to look for. :sign0017::sign0017::sign0017:


text: Hey guys, a few days ago I used the dupli color spray to paint my replacement fender and it looks almost perfect exept the shine or lack of. Is there a way to get that factory paint gloss?? I put a few coats of clear that was sopost to make it glossy but didn't do the job.


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Well, the twin crank fired 16.25 inch 1919A4's are hard on the ammo budget, but a great deal of fun!
Kevin from downrange.com was setup right next to my BP 81mm Mortar (you can see the base plate behind my foot) and the muzzle blast was worse from my twin shorty 1919's then his M2.
The shorty version of the 1919 (any caliber) is very popular (if I remember correctly the last shoot we had around 14 1919's on the line, and half were shorties).
What would be interesting is to mount a muzzle brake (like those on the 50 rifles) but in reverse, to redirect the gases forward and to the sides at a 45 degree angle. I would make a pretty picture lol
So many toys, so little time (or money)


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Mardi Gras Stop Light Party Mardi Gras Stop Light Party at Foundation Room
Join us in Foundation Room from 6pm - 9pm for a Stoplight Singles Party with complimentary red yellow and green cocktails for the first hour or until supplies last
6 pm – 4 am
No Cover
The Las Vegas Foundation Room provides breath–taking view of the Las Vegas Strip from high atop the Mandalay Bay. Members will enjoy private access to our fine dining restaurant, an exotic lounge, seven secluded rooms, and banquet space.
Las Vegas, NV 89119 (702) 632-7631
Real time stream from our members with confirmed users at local venues!
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Check back here often to view user reviews and ratings. Better yet, visit Foundation Room and post your own review and rate their performance!


text: Do you guys think Dallas will play for next year if the losses keep piling up? If they drop 3 more games why not give Parnell a look at RT and Leary or Arkin a look at RG?? Maybe they will suck even more but maybe not. If the season is done for I would like to see what the other players got. The coaching staff sees something in Parnell so lets see what he can do on the field.


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Arlene Gamache is just one foster grandparent helping area kids
It is no secret that children thrive on supportive families and positive role models. Grandparents are often a source of both, but for the times when grandparents aren't, or can't, be around, there are sometimes people like Arlene Gamache.
Gamache knows that children need encouragement and she is not hesitant to admit that she enjoys being able to give that to them. That's why she is a foster grandparent at Pine River-Backus School.
Gamache has been fostering at PR-B for 10 years. It all began when her husband passed away. She found that she had a lot of time on her hands, so when a friend from church introduced her to the Foster Grandparent Program, she signed right up.
Since then, Gamache has bonded with many students; some she had never met before and some were her actual grandchildren. Regardless, her role is the same: to root for the kids in her classes so they know they are supported.
"I like Grandma Arlene because she helps us with a lot of our work," said third-grade student Kaylee Rice.
Gamache acts as a teacher's aide, but a very special one — one who hugs. She assists students not only with their academics, but also with their emotions. She donates most of her time to Susan TeHennepe and her third-grade class.
"They love her because she's a grandma and a lot of kids don't have grandmas around," TeHennepe said. "A lot of kids come to school with different things. They had a rough start or their pipes were frozen and if they come and a grandma's not here they're just crushed. It doesn't matter who else is here, they need a grandma, and that's one of the things I always hear, 'I need my grandma'. It's just that rock."
Grandma Arlene's presence in the classroom isn't just helping the students, either. Even the students can tell you how important she is to Mrs. T.
"She helps Mrs. T by helping her do the corrections on all of our papers, 'cause she has a lot of them," student Jake Mills said.
"I would be lost without them," TeHennepe said. "It's just huge the impact they have on kids. It is so special and I keep saying if they quit, I retire, because I'm done for. There's no way I would survive without my grandmas."
That's not all, because, believe it or not, Gamache considers herself the lucky one in this situation.
"I get many hugs every day," she said. "It's just very enjoyable and the kids are so fun and sweet. I get more than I give, I think."
Gamache is not the only foster grandparent. Between Pine River-Backus Elementary School and the Backus Head Start there are currently nine foster grandmothers. The program is sponsored by the Corporation for National Service and the Minnesota Board on Aging and administrated by Lutheran Social Service.
The program began in 1965 as a way to encourage seniors to do community service. Pine River-Backus Elementary School has had foster grandparents for more than 10 years.
These volunteers are valuable aides at the school and they volunteer a minimum of 10 hours at the school each week.
"This is a program that makes a difference in the lives of kids, and also in their academic progress. Schools are always willing to partner with us. I am proud to know that our volunteers change lives every day," said Mar Kuha of Lutheran Social Service. "Arlene is a shining example of how important senior volunteers are to the fabric of the community."
Though PR-B does not currently have any foster grandfathers, the school is open to the possibility.
All foster grandparents are expected to be kid-friendly and must go through a background check before being hired. The volunteers in this program provide support for students, teachers and even parents by helping to nurture young children. The program is supposed to result in not only better grades and happier children, but also improved relationships between different generations.
If you are 46 or older and would like more information about volunteering as a foster grandparent, contact Mar Kuha at firstname.lastname@example.com or 218-547-4626.


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Individual Tumor Profiling
Has Tumor Molecular Profiling Enabled More Effective and Less Toxic Cancer Treatment?
Top 10 Under 40
Up-and-Coming Stars Shine in Biopharma Research and Business
Podcast: FDA's New Commissioner Hits the Ground Running
Scott Gottlieb, M.D., Commits to Speeding Up Drug Reviews, and Maintaining Safety and Efficacy
Liquid Biopsies Remain Wait and See for Some Clinicians
Circulating Biomarker Assays Promise to Refresh Cancer Profiling and Monitoring Practices
Medicine: Getting Personal
Click Image To Enlarge +Scientists at UC-San Diego have used mice's own red blood cells to create nanoparticles for delivering anticancer therapeutics to tumors in their bodies. [Fusebulb/Fotolia]
No aspect of biopharma better epitomizes the goals and promise of delivering personalized medicine to treat and perhaps even cure intractable and disabling diseases than the emerging fields of cell and gene therapy.
Adding to the excitement surrounding these technology-driven treatment approaches are their recent advance to the marketplace and increasing examples of progress in meeting clinical-scale production and regulatory challenges and achieving commercial success.
The progress and opportunities, obstacles and solutions, and optimistic projections and cautionary portents were all part of the science, technology, economic analysis, and insights presented, debated, and discussed at the recent "Phacilitate Cell & Gene Therapy Forum".
Mahendra Rao, Ph.D., director of the NIH Center for Regenerative Medicine and head of the Laboratory of Stem Cell Biology at the NIH, led off the meeting and highlighted a key distinction from previous years: the growing number of commercial products now available for regenerative medicine.
Success begets new challenges, however, and Dr. Rao identified some of the issues this new reality is creating for young biotechnology companies. These may include how they ship their product, how to make a profit, how to deal with reimbursement and insurance issues, and how to manage competition.
The unique characteristics of cell therapies present new hurdles for this fledgling industry sector: individualized products prepared in small and even single doses; entirely or largely manual processes that need to be automated; and the challenges associated with reducing the cost of goods and leveraging economies of scale.
Other critical factors related to the actual products include storage, transport, time- and temperature-sensitivity, and time-out-of temperature specifications; chain of custody, overall quality control issues; and logistics considerations across the supply chain.
The main take-home message was to start thinking about factors related to commercialization of a cell therapy product early in its development, and at every step along the way—including, for example, the potential impact of a change in a process, protocol, raw material, or analytical method.
Also emphasized by several presenters was the inevitable move toward automation, in the short-term at least aimed primarily at allogeneic cell therapies. Automated processing of cells and cell-based products will be essential for achieving optimal quality control and standardization, designing closed, disposable process streams, eliminating the risks associated with manual intervention and open systems, and reducing costs.
Moving to the Market
A roundtable discussion among a group of industry executives who have navigated the process of cell therapy commercialization focused on the question, "what does a commercially successful cell or gene therapy look like?"
One example was CartiStem®, developed by Medipost, and approved in 2011 in Korea for cartilage regeneration in the treatment of traumatic and degenerative osteoarthritis. The product has been used in about 250 patients but is not yet reimbursable. CartiStem is in Phase II trials in the U.S.
John Maslowski, vp scientific affairs at Fibrocell Science, which markets the aesthetic autologous human dermal fibroblast product azficel-T (LAVIV®) to improve the appearance of wrinkles, spoke about the labor-intensive nature of current autologous cell manufacturing processes.
Geoff MacKay, president and CEO of Organogenesis, described the company's semi-automatic manufacturing process in place to produce its recently approved Gentuit™ product, composed of allogeneic human keratinocytes and fibroblasts, for oral tissue regeneration around teeth and implants.
For TiGenix, key hurdles in bringing to market its ChondroCelect® autologous cartilage product for the repair of single symptomatic defects have included lack of regulatory harmonization, and the need to reduce the cost and increase the effectiveness of therapy. Access drives uptake, the company has found, and its commercialization strategy has included offering regulatory authorities cost controls and volume caps, identifying and targeting patient subgroups likely to have the best outcomes, and pursuing a stepwise, managed market introduction. TiGenix presents the product to physicians and regulators as a value proposition, with evidence-based results and support services.
Driving Market Uptake
Reed Tuckson, M.D., evp and chief of medical affairs, UnitedHealth Group, one of the largest healthcare insurers in the U.S., told the attendees, "We believe you need to succeed and we believe deeply in innovation." It is important to facilitate access to these new products and technologies, he added, but at the same time, he expressed real concern about the dire implications of escalating healthcare costs in the U.S., for which consumers will bear the burden going forward.
There is too much waste in the system now, noted Dr. Tuckson, and too many aspects of healthcare are poorly managed. The prospect of adding increasingly complex and costly therapies into the mix, such as cell therapies, is extremely worrisome from a payer's perspective. It would not be acceptable to waste or misuse these potentially life-saving innovations.
Dr. Tuckson described three emerging strategies essential for the future of the healthcare industry: value-based designs that emphasize individual accountability; value-based reimbursement design that will replace the fee-for-service paradigm; and value-based technology assessment, in light of optimizing outcomes and looking at the total cost of care—for example, a treatment that can provide a lifelong cure vs. a lifetime of medication, and options that allow for oral vs. parenteral therapy or outpatient vs. inpatient treatment.
He encouraged companies developing cell therapies to begin talking to insurers early. "We need to know how it will work and how it will be used in the real world," he said, urging companies to provide data, identify an optimal patient population, and develop unit cost projections.
Automation Is Critical
From the perspective of efficiency and economy, the consensus among presenters was that manufacturing of cell-based therapies will have to move toward more automated processes. Automation and closed process streams are becoming more commonplace in the allogeneic cell therapy setting, and autologous product development strategies will have to follow suit. Even with autologous cell therapy, companies need to think in terms of volume, scale, and platform technologies, urged the speakers. Scale, however, need not necessarily imply scale-up, as in the traditional pharmaceutical manufacturing model, but instead scale-out, producing multiple individualized products in parallel.
Overall, the presenters were optimistic that cost would not be an obstacle to successful commercialization of cell therapies in the future, and attractive cost/benefit ratios will be achievable. They offered insights and suggestions for minimizing cost of goods, maximizing efficiency of operations, developing best practices, and optimizing manufacturing and business models.
Knut Niss, Ph.D., senior R&D manager, Stem Cell Initiative, EMD Millipore, distinguished between the needs in producing an autologous cell therapy—low cell numbers, a fast process, and one manufacturing run/patient—and an allogeneic product, in which the aim is to generate as many doses as possible in a single batch, with the goal of moving toward bioreactors for large-scale manufacturing.
Kim Warren, head of development services for cell therapy at Lonza, commented on one of the challenges in moving the production of adherent cells to bioreactors and the use of microcarriers to increase cell yields. Ideally it would be better to move away from microcarriers and go to cell clusters, but that is "easier said than done," Warren said. Another challenge is how to isolate the cells from the large volumes used in bioreactors. "I don't think we have the downstream technology yet," added Warren.
An important target for reducing the cost of goods in allogeneic cell therapy is the media in which the cells are grown, and decreasing or eliminating serum and other animal-based components. Warren noted, however, that these would have to be replaced with recombinant growth factors and supplements, and the cost of those remains relatively high due to limited demand. We are caught "between the problem of supply and demand," Warren said. Another concern when bovine serum and animal proteins are removed is whether the cells change in any fundamental way.
Frederick Miesowicz, COO and vp of manufacturing at Argos Therapeutics, presented a case study summarizing the do's and don'ts of an automated approach for scale-up of personalized immunotherapies. Argos is automating its Arcelis personalized immunotherapeutic platform technology. The method involves capturing all of the unique antigens from a patient's tumor and developing an immunotherapeutic agent that targets the patient's mutated tumor antigens without provoking an autoimmune reaction, thereby sparing the healthy tissue. The company has a product in a Phase III trial in renal cancer.
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text:
I swear 2013 is flying by way too fast. It's already the third week of February and I still haven't posted my January summary. I am changing the format of these posts yet again. In my attempt to simplify, I am just calling these recaps instead of favorites so I have free rein on what I include. Watch out!
January 2013 Recap
1) I took the plunge and registered for my first half marathon in March. It's a big time commitment, but I have been following the Hal Higdon plan so all the workouts are scheduled.
2) Football playoffs kept us interested all month and a good background for the huge amount of grading Nate did at the end of his semester. I loved Ray Lewis's "Hot in Herre" entrance to his last home game and made Nate play it a couple of times for me (check it out here if you didn't see it).
3) I began to embrace simple recipes I could prep and serve within an hour. Time management in the kitchen has never been my strong suit, but the less time I spend cooking means more time for running and other projects!
4) My big purchase on the month was two fiddle leaf figs from IKEA. One is in our front room in a pretty purple pot. I am still looking for the perfect white ceramic pot for the second plant that's going in our bedroom.
5) My neglected office was finally finished with some sweet rearranging and a lot of clutter removing.
6) We took a break from grading went and saw John Oliver perform on a Friday night. Most know him as a correspondent on the Daily Show, he also has a podcast that is a favorite of Nate's. I surprised him with front row tickets to the show and afterwards we were lucky to get a photo.
7) I started drinking coffee again after a little after holiday detox. Starbucks started selling $1 reusable cups that only strengthen my love affair.
8) In the kitchen, I began a bunch of small projects including a chalkboard wall.
9) My first anniversary with Instagram came and went. I still can't get enough of the application and now you can even follow along online. My user name is andiezoe if you also use the app. Add me as a friend and I'll do the same!


text:
I can pick a handful of games from the 2011 season. My what a year.
Printable View
I can pick a handful of games from the 2011 season. My what a year.
The game against the Raiders in 2009. Statisitically it was his best although it was such a beat down he only played about 1 half of the game before Carr came in.
8-10 completions
173 yards
17.3 average
2 TD / 0 INT's
and a perfect QB rating of 158.3
At SD, 2005.
put Eli on the map.
My favorite game will always be the wild card round against the Falcons. Besides that safety, Eli was just crazy that game.
SF NFC Championship game. Best ever by far. We've had a good line for most of Eli's career. He rarely gets touched, but that game he got worked, and I mean WORKED! He never lost his cool. Even the great ones start throwing the ball up after hitting the turf half like he did in that game, but he just kept firing darts, making great decisions. Probably the best defense he ever faced.


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Qualcomm COO Mollenkopf Takes Stage, Answers Fairly Little
Steve Mollenkopf, who is currently COO of Qualcomm (QCOM) and who is the CEO-designate when Paul Jacobs turns over the reins this Spring, took the stage at the Mandalay Bay hotel convention center this afternoon for a free-form Q&A.
Not much, if anything, was answered. Mollenkopf was asked about the rumors he had been on the short-list to run Microsoft (MSFT) just before the company named him Jacobs's successor. He batted it away by first joking the author of the Bloomberg article, Ian King, was in the room, and to ask him. Then he ended the matter to say Qualcomm is a great company at which to work, and that he was happy the company is a good partner with Microsoft.
He was asked about a corruption investigation into the company's practices by the Chinese government, to which he had nothing to offer.
Perhaps the most conspicuous omission of the session is that no one present asked Mollenkopf point-blank whether the company is at risk of losing share in the wireless baseband chip market, which is being targeted by a plethora of competitors, including Intel, MediaTek (2454TW), Broadcom (BRCM), and Nvidia (NVDA).
The impression, however, upon those with whom I spoke who were also in the room was that Mollenkopf came across as articulate, sharp, and very CEO- sounding, which means this dry run at running the show was a success for him and the company.
It didn't really matter, however, that nothing much substantive came out of the event. For, earlier in the day, the company's own announcements at the show — a new processor design for interactive audio and video, among other things, — was overshadowed by a leak this morning of Samsung Electronics's (005930KS) announcement, expected this afternoon, that it is going to use Qualcomm chips for future tablets, an apparent set-back to Intel's "Bay Trail" chips.


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Twitter only recently released Vine, an app that lets users post 6-second video clips in loop, hitting the App Store last week. Early adopters were quick to share video clips of their pets, food, traveling and friends, but others quickly discovered that Vine can be used in more mischievous ways, like sharing adult content.
First off, Vine doesn't actually prohibit users from sharing nude or pornographic content with the app as long as it doesn't violate copyrights, and the sole responsibility for the videos rest on users, not Vine.
According to Vine's Terms of Service, these are the things one cannot post on Vine. Videos that:
- Impersonates another person or entity in a manner that does or is intended to mislead, confuse, or deceive others;
- Violates the rights of a third party, including copyright, trademark, privacy, and publicity rights;
- Is a direct and specific threat of violence to others;
- Is furtherance of illegal activities; or
- Is harassing, abusive, or constitutes spam.
Vine's Terms of Service also states that users should only share content that they are comfortable sharing – which means, if you are comfortable with showing the world your body or private acts such as having sex, then go on and do it.
"You are responsible for your use of the Services, for any Content you post to the Services, and for any consequences thereof. The Content you submit, post, or display will be able to be viewed by other users of the Services and through third party services and websites. You should only provide Content that you are comfortable sharing with others under these Terms," Vine's ToS read.
Vine was acquired by Twitter so it has some of the microblog's features, such as hashtags for easy search and discovery. Hashtags such as #porn, #sex, #ass, #masturbate and #NSFW make porn search much easier on Vine's platform. People can also comment on hashtags, just like Twitter. And because Twitter has always been censorship-free in most countries, the same goes with Vine.
The ToS warns users that they may be exposed to "Content that might be offensive, harmful, inaccurate or otherwise inappropriate, or in some cases, postings that have been mislabeled or are otherwise deceptive." Since users are responsible for content shared, Vine is not "liable in any way for any Content, including, but not limited to, any errors or omissions in any Content, or any loss or damage of any kind incurred as a result of the use of any Content posted, emailed, transmitted or otherwise made available via the Services or broadcast elsewhere."
By agreeing to Vine's ToS, users are giving Vine "a worldwide, non-exclusive, royalty-free license (with the right to sublicense) to use, copy, reproduce, process, adapt, modify, publish, transmit, display and distribute such Content in any and all media or distribution methods (now known or later developed)." Simply put, though you own the rights to your videos, you gave Vine the right to use your content however they want to use it.
So does that mean Vine users should just put up with all the porn readily available, even for kids that have access to the site's content?
Users can fight bad content
According to Twitter, those who are disturbed by the abundance of pornographic videos available on Vine can report the videos deemed appropriate, such as those containing nudity, violence, or medical procedures. Once the videos are reported as inappropriate, a warning message will be added before the video plays, alerting viewers of inappropriate content. If more people report the video, it will be sent for review by Vine with the possibility of being removed, the account suspended or even terminated.
"We may suspend or terminate your accounts or cease providing you with all or part of the Services at any time for any reason, including, but not limited to, if we reasonably believe: (i) you have violated these Terms, (ii) you create risk or possible legal exposure for us; or (iii) our provision of the Services to you is no longer commercially viable. We will make reasonable efforts to notify you by the email address associated with your account or through the Services the next time you attempt to access your account," Vine's ToS reads.
Risk of being ousted
Vine is available for download in Apple's App Store, which is known for being strict with apps that make nudity and mature content easily available to anyone, especially younger users.
Last week, Apple pulled photo sharing app 500px from the App Store for reportedly making nude photos easily available to consumers. And last year, Viddy, a video sharing app, was pulled from the App Store because it has too much porn.
It's a likely possibility that if Twitter doesn't filter Vine's content, the app could be pulled from Apple's App Store and possibly banned from other app stores.


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Chef's Hat: Cajun Style Potato Salad
Cajun Style Potato Salad
3 pounds Yukon gold potatoes, scrubbed
1 1/4 cups light or regular mayonnaise
1 tablespoon Cajun or Creole mustard
1 tablespoon Cajun or Creole seasonings
1 cup thinly sliced celery
6 hard-cooked eggs, diced
1/2 cup sliced green onions
2 cups shredded sharp cheddar cheese
1/4 teaspoon salt
1/4 teaspoon pepper
Hot sauce (optional)
Cook potatoes in boiling water 20 minutes or until tender. Drain; cover with cold water until cool enough to handle.
Meanwhile, combine mayonnaise, mustard, seasonings, celery, eggs and green onions in large bowl; mix well.
Cut cooled potatoes into 3/4-inch chunks. Add potatoes, cheese, salt, pepper and hot sauce, if desired, to bowl; mix well. Cover and chill at least 2 hours or up to 24 hours before serving.
If you like larger pieces of eggs, slice the eggs instead of dicing them. And instead of adding them with the mayonnaise, add them after everything else and lightly toss them in with the mixture.


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Players come and go on the Free Agency Merry-Go-Round, but the N.Y. Giants will always be here!
at a loss for words. unreal this guy
Got to love it im not even a tebow fan but you have to appreciate his intensity maybe our teams needs a little of that... One thing for sure you dont see the Broncos quitting.
That's what the headlines will be. Of course, it's not all him but he makes everybody around him better. Oh, and Denver has a pretty good defense, so there's that.
It so happens, I'm an atheist but I tell everybody "He's got God on his side so how can he lose?" Just to piss off the haters.
I root for the guy every week. I don't understand how you can't like the guy and root for him. He can't play QB for **** and he probably won't be in the league in two years but, until the Giants have to face him, I just hope he keeps winning.
Wow, I thought when the Bears went up 10-0, the Broncos were done, considering the lack of offense on the Broncos. A lot of dropped passes for the Broncos. But Tebow just wins! I bet the Chargers thought they would gain some ground since the Raiders got whooped. </P>


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A person who pretends they are a native of California. The truth is they have lived in their home town their whole lives and have only been on Choir tour and family vacations to California. They say words like tight, bra, homie and dawg. You can spot a Califaker in the crowd by their Hollister shorts and flip-flops in the winter.
I hate that douche, he is the biggest Califaker.
by d-licious January 21, 2008
People who basically act like and say they're from California, but their not. They tend to wear clothing like Hollister. Basically it's people whose insecure about their native state.
Californian-So dude, where are you from?
Cali-Faker-I'm from Cali bra, ya these hollister clothing are awesome!!
Californian-Dude, shut the fuck up.
Cali-Faker-I'm from Cali bra, ya these hollister clothing are awesome!!
by Tommeee April 08, 2008


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Is anybody raising AB I think there ought to be a good discusion on these bees. I have surf the net about AB and I have found conflecting things about AB which say that you can kill the AB queen and instal a European honey bee queen and she will somewhat calm the hive down.
Right now there here Texas and other southeren states and it's just a matter of time they will be in your area and you will know when the bees start getting mean and chase you down the raod about a 1/2 a mile.
You ones that said to me I live in Texas around Houston and my bees are EHB ok so far your the lucky ones but its just a matter of time and you will be dealing with them
I'm just starting out bee keeping and I have two hives one in the wall of my shop and one in the eave of my house and I was ask how do I know there AB and not EHB well I can set out about 3 to 4 feet and not bother them just watch them and of course I have my bee suit on and stat attacking me for no reason at all and I have seen video on EHB and they even pick them up and with no bee suit.
Well anyway is anybody raising AB and if so # 1 do you have to mow with your bee suit on # 2 how far away should the AB hive be before they will not attack you. # 3 Has it been worth the hassil raising AB.


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Originally coined by Shakespeare in the opening line of Richard III: "Now is the Winter of our Discontent / Made glorious summer by this son of York", written around 1592. It was used to describe Richard III (from the house of York), feeling discontented in living in a world that hates him. The term has since then been used in various forms, such as 'The winter of discontent', describing the winter of 1978–79 in the United Kingdom during the Labour party pay caps of the time. It was also used 'Now is the winter of your discontent!' by Stewie Griffin in the TV show family guy before Stewie attacks Brian with a snow-cannon.
A man and his family are sat in their house in the middle of winter with no money and no front door. The man says "Now is the winter of our discontent"
by DisgruntledGentleman September 03, 2013
The vengeful act of crapping on a lover's chest while they sleep.Buy the plush


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1301 McKinney, Suite 5100
Houston, Texas 77010
United States
|Law School
|University of Virginia
|University of Virginia
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Associate Attorney
Hendershot, Cannon, Martin & Hisey, PC – Galleria Area based law firm is seeking a Litigation Associate Attorney with 3 to 5 years experience with emphasis on commercial litigation. Some probate and...
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Houston Office of National Firm seeks New Partners with AmLaw 200 Background (8+ yrs)
Culhane Meadows PLLC, one of the largest national non-traditional law firms in America, seeks experienced partner-level attorneys in Houston. We are actively recruiting new partners who are aligned w...
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Commercial Counsel The candidate primary responsibilities will be to provide comprehensive commercial legal advice to one or more Business Divisions of Huntsman. The position is an integral part of ...
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A. Harrison Barnes is a well-known attorney throughout the United States. As a member of the Malibu community, Harrison is committed to serving the needs of Malibu residents and businesses in legal matters.
Benjamin P. Smith is a partner in Morgan Lewis's Litigation Practice. He is a trial lawyer with a particular focus on high-stakes disputes in the biotechnology, medical device, and internet industries.


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Torrington >> Voters will have the opportunity to decide who will serve as 8th district Senator on next Tuesday's Election Day. The draw is between Republican Senator Kevin Witkos, hoping to keep his seat as two-term 8th district Senator, and Democrat Dan Seger, trying to unseat incumbent Sen. Witkos.
Sen. Witkos is hoping to defeat opponent Seger in order to embrace a third term in the 8th district, a region that has been solely dominated by the Republican party since at least 1971. Witkos gained his seat in 2008 after defeating Arnold House and then again in 2010 when he defeated Donald J. O'Brien by over 12,000 votes.
Witkos, grew up in Georgia and then later in Granby, graduated from Tunxis Community College with an Assoicates in Science in 1998 and then received his Bachelor of Arts in General Studies with a focus on Law and Society from the University of Connecticut in 2007. As a retired sergeant of 28 years service at the Canton Police Department, Witkos lives in Canton with his wife Esther and their two children, Kyra and KC.
The Senator said he started his political life when he served as Vice Chairman of the Canton Board of Education and started seeing mandates coming from the state that he didn't agree with. When a co-board member said, "why don't you put your money where your mouth is?" Witkos ultimately had the push to run for public office.
As a three-term State House of Representative before elected as Senator, Witkos focused heavily on education where he took up the cause of students and state boards across the state by introducing key improvements to school testing standards.
Education is a continued passionate policy for Witkos as one of his goals if re-elected is increase spending for education on the local level and bring it up to 50 percent.
"I believe increasing spending on education is not only a smart investment on our future - our kids are the next entrepreneur's and work force of tomorrow - but it should reduce the reliance on our local property tax structure at the local level," Sen. Witkos said.
Witkos voted against the 2011 Jobs bill, a common reprimand from opponent Seger, brought upon by Gov. Dannel P. Malloy because "the bill cost taxpayers close to 700 million dollars of which we could not and cannot afford."
The bill also has given the Governor sole authority over the job's program, taking away the oversight of the legislature when it comes to spending, according to Witkos. This allows "the Governor to pick and choose any business he wants and give them millions of dollars without the consent of the legislature, which had always been required."
As a small business owner, opening a local pub in Canton in early December with his wife, Witkos has an agenda for small business growth.
He wants to focus on "creating a business checklist through legislation and Economic Community Development so small business owners know what is expected of them and what they have to file" if re-elected.
"If we don't make taxes on the business climate community more appealing, no one will want to open," said Witkos.
"I want to work with the banking community to free up money that could go to small businesses."
These missions, according to Witkos, will ultimately boost the economy for small businesses and draw more people into the community.
"If you start creating more jobs, maybe more young people would stay and give them something to do like small night clubs or bars," he said.
The Senator said his past experiences in government have been strong assets as a candidate for re-election. "I have proven myself to my constituents that I am dependable, open and honest and want to keep as much of their money in their pockets, not in Government pockets."
The Democrat contender looking to steal the 8th district Senate seat, Dan Seger, is also hoping to prove himself worthy of local voter's votes.
Seger, born in St, Louis and then a native of the 8th district since 1972, retired earlier this year from Perry Technology Corporation in New Hartford, where he worked as plant manager since the mid 1980s, doing technical sales and negotiating contracts with customers around the world for aerospace products.
Running his own company, Connecticut Web Services LLC that is based full-time out of his home, Seger lives in Canton with his wife. His three children and three grandchildren live in the 8th district as well.
Seger, never "politically inclined," began his political life when he was approached by the Democratic Committee in Canton. Due to his small business and life experiences in the Canton region, the Committee thought he would be a good choice to run for the 8th district Senator seat.
"I didn't think our (8th district) representation and our current Senator was well-equipped with small businesses," Seger said, who was endorsed by the Uniformed Professional Fire Fighters Association as well as the Connecticut Police and Fire Fighters Union.
The promotion of small businesses and the economic development of them is a significant goal for the contender "since they are the backbone of the state."
"I want to try and make Connecticut a place where our kids can find jobs in the towns that they grew up in," said Seger.
He has put an emphasis on his disapproval of Sen. Witkos voting against the 2011 Job bill.
The bill has "helped small businesses across the state and have added hundreds of jobs," according to Seger, who recently met with Circle Commerce in Avon, a business that has developed their own marketing group after 25 years, a repercussion of the bill.
Sen. Witkos role as state chairman for ALEC, a national lobbying organization, is considered by Seger "to be just not right."
"My opponent is out of touch with the needs of his constituents and is looking out for the special interests and the energy companies," said Seger. "We need representation of our interests, not big business."
In terms of education, Witkos's opponent, said that money should be put back into the classrooms along with trust in the teachers.
"We need to continue to work to ensure that schools receive funding and teachers receive support so that we can close the achievement gap," said Seger.
Ultimately, Seger is looking for voters in the 8th district to see that he will be "a change for the better,"
"I'm here eagerly hoping to be the new voice in Hartford for small businesses. I'm here to listen and learn from the 11 districts. We need to look at each town as its own entity."
No matter who the 8th district decides to be their representation for the next two years, both candidates have plans to boost small businesses and reach out to educational focuses in order to satisfy the region.
Kevin Witkos can be reached at 1-800-842-1421 and Dan Seger can be reached by visiting www.segerforsenate.com.
Sarah Bogues can be reached at 860-489-3121, ext. 328, or by email at email@example.com.


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Jesus now 49ers fans are talking trash in the regular forum... it's going to be a long week. And let me say if 49ers fans did that last year and made fun of 9/11 that is as classless as it gets. I just read that and it made me sick, my cousin died that day he was in the towers and that is just sickening....
i like that the 49ers have had 2 almost BYE weeks with no competition ... at least we spotted the Brownies some points to make it interesting
plus every media head on the planet will pick them
plus we will be on the road doing our road warrior thing
im feeling pretty good about this game ... but even as a non-division game ... im expecting playoff like intensity
Apologize to Melo 5
"Everyone has a plan until they punched in the mouth" - Mike Tyson
I've lived in California post 9-11 and people there are just indifferent towards the terrorist attacks as if it happened to another country, I guess they just simply do not comprehend the degree of devastation because it didn't happen to their immediate surroundings. Those moronic 49er fans who use 9-11 attack photos to mock the Giants clearly do not have enough brains to understand that what they are doing is being anti-Americans.
Hey, I'm just going to not react to it and when a huge tsunami hits California and washes away their 49ers goodies into the ocean, I'm going to laugh out loud without any guilt.
I could not go to Korea for my next assignment any sooner, California sucksssss


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AICPA Professional Library for the Academic Market
Product Information
The AICPA Professional Library for the Academic Market is available as an add-on with a subscription to any other Financial Reporting & Management product or package on Checkpoint. By subscribing to this library, you get a complete, powerful solution for your financial reporting and compliance needs that keeps you fully informed.
With this add-on package, you can go one step beyond WG&L's renowned accounting and financial reporting analysis, going directly into the AICPA's complete library of Statements of Position, Auditing Standards, Audit and Accounting Guides, and other primary source material.


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The sister city concept evolved from President Eisenhower's "People-to-People" program, established in 1956 to lessen the chance of future world conflicts and to involve people from all walks of life in personal diplomacy.
Bellevue has four sister cities, in Taiwan, Japan, the Czech Republic and Latvia. Separately, Bellevue has international trade cooperation efforts underway with cities in China and India. These international efforts enrich the cultural and business profile of our city, and they provide a meaningful connection between Bellevue's richly diverse population and numerous areas across the globe.
The Bellevue Sister Cities Association offers more information and calendar updates.
Sister Cities Liaison
450 110th Ave. NE
P.O. Box 90012
Bellevue, WA 98009
Contact: Gregg Schrader
Phone: 425-452-6451
E-mail: email@example.com


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DEVELOPER: Bethesda Game Studios
PUBLISHER: Bethesda Softworks / 2K Games
PLATFORM: PC and future generation consoles
GENRE: Role-playing
Oblivion is the quintessential role-playing game for the next generation and another leap forward ingaming. Step inside the most richly detailed and vibrant game-world ever created. Oblivion is the latest chapter in the epic and highly successful Elder Scrolls saga and utilizes the latest PC and nextgeneration video game hardware to fully immerse you into the experience. With a powerful combination of freeform gameplay and unprecedented graphics, you can unravel the main quest at your
own pace or explore the vast world and find your own challenges.
After the mysterious and untimely death of the Emperor, the throne of Tamriel lies empty. With the Empire ready to crumble, the gates of Oblivion open and demons march upon the land - laying waste to everything in their path. To turn the tide of darkness, you must find the lost heir to thethrone and unravel the sinister plot that threatens to destroy all of Tamriel.
í¢â'¬Â¢ Live Another Life in Another World. Create and play any character you can imagine, from the noble warrior to the sinister assassin to the wizened sorcerer.
í¢â'¬Â¢ Next Generation Graphics. Pixel-shader effects and high definition televisions are fully supported to create unprecedented visuals, including lifelike towns, dungeons, and the most realistic forests ever created in a game.
í¢â'¬Â¢ First Person Melee and Magic. An all-new combat and magic system brings first person role-playing to a new level of intensity where you feel every blow.
í¢â'¬Â¢ Radiant AI. This groundbreaking AI system gives Oblivioní¢â'¬™s characters full 24/7 schedules and the ability to make their own choices based on the world around them. Non-player characters eat, sleep, and complete goals all on their own.
í¢â'¬Â¢ Realistic Characters. Oblivioní¢â'¬™s features over 1,000 non-player characters who come to life like never before with facial animations, lip-synching, and full speech. They even engage in unscripted conversations with each other and you.
í¢â'¬Â¢ Open-Ended Game Play; Short Challenges. The enormous world of Oblivion is open for you to explore at your own pace, and shorter challenges such as fighting bandits, mixing potions, creating magic items and persuading friends keep the challenges coming.


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Maybelle Peterson
Maybelle Peterson
Formerly of Pine River
Maybelle Peterson, 87, formerly of Pine River, passed away Saturday, Sept. 21, 2013, in Northfield, Minn. She was born to Charles and Grace Sevesind on May 16, 1926, in Gettysburg, S.D.
Maybelle is survived by her children: Carol Malz, Larry Peterson, Charles Peterson, and Walter Peterson; 14 grandchildren and several great-grandchildren; brothers: Leo Sevesind and Wilbur Sevesind.
She was preceded in death by her husband, Martin.
A gathering of friends and family to celebrate Maybelle's life will be Sunday, Sept. 29, from 1-3 p.m. at Kline Funeral Home, Pequot Lakes.


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5 Food Inventions by Black Inventors
Wednesday, February 29th, 2012 | Posted under Black History, Food Culture
If you've noticed that I didn't do any Black History Month posts re: food, you're perceptive. I know that there are historical figures in food, but it took a little more effort to find them than I thought it would. I found these five inventors and their inventions and were surprised by many of them.


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A three year old "Egg Donor Queen" finally expired. I let this nuc grow two replacement queen cells. This morning I observed that one of them had emerged and that she had destroyed the other cell. I then located her, she wasn't outstanding, but was a nice looking virgin.
In a few more weeks I hope to discover that she successfully located drones and is well mated. All of my own hives are still drone-free, though the strongest hives have fair quantities of drone brood, but still quite a ways away from abundant sexually mature drones. It is possible that feral colonies have plenty of drones, and that my virgins are possibly mating with a majority of these feral drones anyways.


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Sign up for fall soccer in Nisswa
Nisswa Park and Recreation's fall soccer program is open to girls and boys in grades K-12.
The program will stress team play, sportsmanship, participation and fun. All participants will receive a team T-shirt.
The first practice will be Sept. 7 at the Nisswa Park baseball field. The season will end Oct. 17, or sooner, depending upon weather.
Practices/games will be on Tuesday or Thursday nights and Saturday mornings. Practice dates will be set by coaches.
Grades K-3 will practice from 5:30-6:30 p.m. Tuesdays and from 9:30-10:30 a.m. Saturdays.
Practices will work on fundamentals, skills, ball handling and scrimmaging. Players are encouraged to wear shin guards and must wear tennis shoes or rubber cleats.
Co-ed teams will be formed by grade levels: grades K-1, 2-3, 4-6 (coached by Clark Hickman), 7-8 and 9-12.
Team schedules are being finalized with teams from Pequot Lakes, Crosslake, Pine River and Baxter. Practices and home games will be at Nisswa Park.
All game schedules and team communication will be emailed to parents.
Participation fee is $44 per participant and includes T-shirt. Registration and check made payable to Nisswa Park & Recreation should be mailed by Sept. 5 to P.O. Box 410, Nisswa, MN 56468.
Additional questions may be emailed to firstname.lastname@example.com.
Pond Hockey information is at www.ci.nisswa.mn.us.


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News and Announcements Archive
Wayne Law Welcomes New Legal Research and Writing Faculty Members
DETROIT (Aug. 1, 2008) – Wayne State University Law School is pleased to announce the addition of three faculty members who will join the Law School's Legal Research and Writing team. They include new Director Anne Marie Burr, Aimée Mangan Bacik and Kathryn M. Day.
"I would like to congratulate and welcome new members of our Legal Research and Writing team," said Wayne Law Dean Robert M. Ackerman. "Their extensive experience will only enhance Wayne Law's already impressive reputation for training outstanding legal writers. They join a great team and I look forward to working with them."
Anne Marie Burr will serve as the director of Legal Research and Writing. Most recently, Burr was employed with the Ave Maria School of Law as an assistant professor of Research, Writing and Advocacy. She has served as an equity partner in the regional law firm of Dykema Gossett, as senior counsel of the multinational corporation Allied Domecq, and as a law clerk for United States District Judge George E. Woods. In addition to Legal Research and Writing, she has taught negotiation, debtor-creditor law, civil procedure and evidence. She has also published numerous articles on commercial law and dispute resolution.
Burr earned a J.D. from Wayne State University Law School, a graduate certificate from the M.A. in Dispute Resolution Program of Wayne State University's College of Urban, Labor and Metropolitan Affairs, and a B.A. from Oakland University.
Aimée Mangan Bacik will serve as a legal writing instructor. She has served as an adjunct instructor and visiting assistant clinical professor at the University of Michigan Law School, as well as faculty services librarian in UM's law library. Other past work experience includes stints as a law clerk to The Honorable Paul D. Borman and with the United States Attorney, Eastern District of Michigan, in Detroit.
Bacik earned a J.D. from the University of Michigan Law School and a B.A. from the University of Michigan.
Kathryn M. Day will serve as a legal writing instructor. Most recently, Day served as assistant professor of Legal Research and Writing at Ave Maria School of Law. She has also held positions such as academic support coordinator at Ave Maria School of Law, president at Lawquest, Inc., vice president at Legal Research Unlimited, Inc., and clerkships at the Illinois Appellate Court, First District.
Day earned a J.D. from Northwestern University School of Law and a B.A. from the University of Michigan.
Burr, Bacik and Day join Wayne Law Legal Research and Writing Faculty Kristin Theut, Clara "Tiki" Scholla McCarthy, Mireille Phillips and Amy Neville.
Wayne State University Law School has educated and served the Detroit metropolitan area since its inception as Detroit City Law School in 1927. Located at 471 W. Palmer St. in Detroit's re-energized historic cultural center, the Law School remains committed to student success and features modern lecture and court facilities, multi-media and distance learning classrooms, a 250-seat auditorium, and the Arthur Neef Law Library, which houses one of the nation's 40 largest legal collections. Taught by an internationally recognized and expert faculty, Wayne State Law School students experience a high-quality legal education via a growing array of hands-on curricular offerings, five live-client clinics, and access to well over 100 internships with local and non-profit entities each year. Its 11,000 living alumni, who work in every state of the nation and more than a dozen foreign countries, are experts in their disciplines and include leading members of the local, national and international legal communities. For more information, visit www.law.wayne.edu.


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We are so blessed to have our close friends standing beside us when we take our vows of marriage.
Katherine and I have been the best of friends since our first day in grade school. We have been through so much together... from playing two square during recess, to double dating for the senior prom, and cheering each other on during our college graduation. She is like my sister and I can't imagine anyone else standing by my side during the big day!
Angie and I were college roommates and instantly clicked the moment we met. We have always been there for each other through late-night study sessions, parties on the quad, or that awesome spring break in Hawaii our senior year. I am so glad that we are still such close friends to this day.
Mel and I have so much fun together! Everything she says makes me laugh, and I love how we always cause such a riot wherever we go. I am so lucky to have a friend like her.
Adam and I go way back to high school. Back then, we'd lift weights after football practice, or work on our pick-up trucks on the weekends instead of doing homework. Nowadays we chew the cud every Sunday morning while watching football over pretzels and beer. Seems like we haven't changed that much!
Mike, AKA Mr. Cool, is the ultimate biker / heavy metal / travel enthusiast. Whenever I call or email him, he's always in some new country... Ecuador, Guatemala, Spain, France, Italy... who knows where he's going next? But don't let the perfectly-coiffed faux hawk fool you... Mike is the most loyal and true friend a guy could have.
Justin is Mr. All American. He was Captain of our football team and homecoming king in high school. Now he's just finishing up medical school at UCLA. He may make the rest of look like slackers, but I couldn't be more proud!


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Last week in the bee yard I was looking through the hives and found some that were incredibly full, so much so that both deep boxes were full of either brood , pollen or surplus honey. I simply grabbed a nearby deadout deep and threw it on top to give them some room. My goal this year is to expand my numbers , and to this end I started feeding early to increase brood production. I have suceeded in the increased brood but now need to take the next step. In the past I have either done a hard split (no attempt to equalize brood just grab the top box and haul to a new site) and let them requeen themselves, or try to locate the queen and move her and 4-5 frames to a new site.
My question is . If I had put the empty deep with drawn comb between the two original deeps splitting the brood nest, would the reduced queen pheremone in the box seperated from the queen cause the bees to begin what they may think is a supercedure?
I know that some here will tell me that splitting the brood nest is a no no but every time we pull a nuc or make any split this is exactly what we do is it not?
My plan would be to then break the top box down into nucs after the queen cells are capped. These cells would be started and finished in the queenright and very full hive so wouldn't they be good well started queens?
I currently have only bottom entrances, OK and some very leaky boxes that the bees come and go through at will. would I gain from providing an entrance above the empty box?
I guess the next question would be how about some kind of double queen excluder between the boxes and letting the new queen mate before moving the top box away?
Is this a crazy plan doomed to failure??????
Gary C.


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