text:
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Re: st: Removing outliers from my dataset
Nick Cox <email@example.com>
"email@example.com" <email@example.com>
Re: st: Removing outliers from my dataset
Wed, 17 Apr 2013 16:33:13 +0100
I think I agree with this, not that there can't be differing views on
a tricky area!
In essence, there should be a story that says why some data points
don't belong. That's more a subject-matter judgment call relating a
decision to research objectives than a statistical decision.
On 17 April 2013 15:43, Clyde B Schechter
<email@example.com> wrote:
> There has been a running thread initiated by a request for assistance in removing outliers from a data set. The gist of the thread has been that removing outliers is, in general, a dangerous approach except in limited circumstances. And the point has been made in the thread that bogus data are often inliers.
> In the particular circumstance, the extreme values that the original poster sought to remove are the result of anomalies in accounting rules as applied to particular special circumstances, so that the values are not meaningful. In that case, while it would make sense to remove them, he should also be removing any non-outlier values that are also the result of the application of those same anomalies in the accounting rules. Those, though not extreme in value, are also not meaningful and, if included in your analysis, are introducing error and may lead to an incorrectly specified or estimated model.
> Removing the data that are known to be spuriously generated by these accounting rule anomalies, irrespective of their values, has an additional advantage. If you just remove outliers, your model has no prospectively defined population to which it generalizes: applicability is conditional on the outcome. By contrast, removing those items that were spuriously generated gives a prospective definition of the population to which the model generalizes.
> Clyde Schechter
> Dept. of Family & Social Medicine
> Albert Einstein College of Medicine
> Bronx, NY, USA
> *
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text:
[quote user="Kruunch"][quote user="BlueSanta"]I dont see it. I love Kuechly as a prospect, but we have too many needs this year, and we do too well with our picks under Reese to trade them away.
I also think you have to be careful not to "fall in love" with any 1 prospect, even if Luke is a stud prospect.
With Goff visiting other teams, if Kuechly drops to us he might very well be our pick.
I just don't see him dropping that far. Great productioin, great college career, solid school, no character issues, great Combine .... he's like the model of what to do as a draft prospect.
His only knock is that he plays a position that's disappearing in the NFL.[/quote]
ya, dont get me wrong, if he somehow dropped to our pick I would jump all over him. I have been saying for months that I thought we should target him. But, I knew after the combine he was likely out of our reach.
It was kind of odd really, I was saying prior to the combine look at his 2 games vs FSU where he was all over the field. I saw him run down Davonte Freeman, who is an well known speedster. Yet, prior to the combine there were scouts saying he had "subpar" athleticism. During the cobime I saw him run and was inwardly like "SEE! I KNEW IT." Then, a moment later I thought, "why am I happy? He just ran himself out of our reach."
The problem is I do not think trading up in the 1st is wise except maybe for a QB. Look at recent trade ups and tell me if you think the teams who did it are happy? Do you think the Falcons, who sold their soul for Julio Jones are happy right now? I know its a bit early, but I would have to say no, they arent. How about the Saints who traded away their 1st this year for Mark Ingram who was their 3rd leading rusher?

subset: commoncrawl


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text: My property contains about 20 olive trees. These were not planted by me but are the very commom wild trees that are reasonably invasive in our area (West Central Indiana). They bloom with small white trumpet shaped flowers that I always figured were too long for use by my honeybees. This weekend, going around the property, BumbleBees were working all the olives. Three of the trees were covered (standing under the trees and shutting your eyes resulted in the trees humming) with honeybees. The other trees were untouched. I could not see any difference between the flowers of the trees. All the trees seemed to be in the same stage of blooming. I don't think there are seperate male female trees like there are in Holly's. Anybody know what's going on?


text:
Lauri recently posted photos of some tiny queen rearing hives she has built. Half the size of a five frame nuc I believe. I am just curious, is the reason for these just to make it so much easier to find the queen?
Lauri recently posted photos of some tiny queen rearing hives she has built. Half the size of a five frame nuc I believe. I am just curious, is the reason for these just to make it so much easier to find the queen?
I think the resources is the biggest reason for using mini nucs. Last year was my first year raising queens and it does take a bunch of bee resources to make up the mating nucs. Its not really that hard to get 30 nice looking queen cells but, making up 30 nucs to get them mated in takes quite a few frames of bees.
The down sides are: not using standard sized frames, which prevents you from using your standard colonies for resources.(brood, stores) A large handicap in my book. Also, most are too small to feasibly use as a wintering box. They would also be much more likely to swarm if left to their own devices. I do see the value of them with large operations though..... Very efficient.
Queen production model where you can get tons of virgins mated then ship out. Large operations would be looking to take those mated queens and ship them almost immediately, rinse and repeat. Whitetail makes some good points, especially if you're wanting to grow out; virgin>mated queen>nuc.
An alternative to the tiny mating nucs is to set up a queen castle. You can use more standard sized equipment and get multiple queens mated in a small space.
Queen castle, perfect for me! Thanks
The last two years I've used a bunch of baby nucs, but have found them far more troublesome, for my style of beekeeping, than the standard nucs.
The normal nucs i run are 3 deep frame nucs, run at 3 to a standard deep super. They go through the winter so after the initial set up no further bee reources are required. The opposite in fact, I have to remove bees and brood from them during the season, which gets made up into hives and sold.
The baby nucs though, most of which were on loan from another beekeeper, were set up with 250 mls each of bees and a queen cell, so it was possible to get a lot of them just from one strong hive. But from then on, they have to be run to a strict timetable, leave laying queens in them too long & they abscond or the queen simply dissappears. As I'm not dealing in large numbers, my order flow can be erratic and the baby nuc schedule has not suited me.
Large breeders needing a lot of queens in a small time frame, with minimal bee resources, could be served well by baby nucs. Likewise a small hobbyist with just a few hives, and wanting a few replacement queens or maybe a small number to sell, could do well with some baby nucs. Seems for me though, I'm somewhere is the middle, and my business which is selling boith queens, and hives, is better served by having all equipment standard, so as nucs get overpopulated, no worries, I sell them.
My 2 cents, but anyhow, baby nucs are an interesting thing to do I'd recommend anyone give it a go, just be ready for some intensive management..
"Thinking Inside The Box"
"Intensive management" is the key here in my case. I am a firefighter on a 24-48 schedule. I can trade and take vacation days during the busy times but for most things I am going to need to miss ten days a month of "intensive management" so queen castles sound really good right now. Of course next year I might think differently
Quick question: How do you stock the mini mating nucs? and with how much/many bees?
I made up my own, they are Il supers deep, and 1/2 the depth of the hive, including the wall. this lets me set 1 or 2 of them on top a regular have to get them charged in the spring. Each one is then divided into 3 sections. 1 small feeder and 2 frames each. 500 bees fills one up nicley, which is about a cup of bees.
It was done inside a large shed, we set the baby nucs out in rows, lids off, and each row was stacked several high. Each nuc had a 250 ml tin of sugar syrup. It was a 2 man job, one guy walked along pulling a comb from each nuc and laying it flat on top of the nuc, and another guy walked behind him with a gas torch and queen cells, he would flame the comb an put the queen cell on, he'd melt the wax just sufficiently so the cell would attach. then we'd dump a couple of packages of bees into a 4 gallon tin, and sprinkle them lightly with water, just enough to stop most of them flying, but not drench them. He would then walk along the row of nucs, dumping 250 ml's (one cup) of bees into each one, the other guy walking behind him putting the lids on. The combs were set in a Y shape, which the cell at the corner of the Y, that is the place the bees would make their small cluster and that is where we had put the queen cell.
The nucs were stacked in the shed for 3 days so that the queen cell would be hatched. Then they were loaded onto the truck and taken out to the yards. Once the queen was laying, we would go along the rows with bees, one guy lifting the lid of each nuc, and the other guy dumping 125 ml (1/2 cup) of bees into each nuc. That enabled the queen to lay a few more eggs which the bees could cover, the queen was then caged a few days later and the nuc given another queen cell.
For someone doiung just a small number of nucs, I would suggest following exactly the same method. Using a nuc box, or anything that can hold a few lb's of bees, take a few shakes of bees from a hive or two, from somewhere out of flight range of where you want to set up the nucs. Set up your nucs, including some feed in each one. Put in the queen cells and dump a cup of bees into each one. You cannot put the nucs in the yard straight away, the queenless bees will drift away. They should be left with the entrances shut for 3 days so the queen cells will hatch, it is very important they are left in a cool place, if the sun shines on them they will cook. After 3 days put them out into the yards. It is essential they have feed, if they don't, in 3 days they will starve.
For someone with just a few nu
"Thinking Inside The Box"
Oldtimer- would you make up nucs with cells the same way if you could put brood in with the cell? Just wondering if I could reduce drift by closing in the bees for a day or two?
If they can have brood that's a huge advantage. It will certainly reduce drift but will not eliminate it. In these little nucs you don't have to lose many bees to take the nuc below survival level.
"Thinking Inside The Box"
I've done a few kinds of mating nucs and really love the mini size. But mine are deep mini frames, not the shallows Mann Laks sells. With five deep mini's I get a decent sized mating nuc that is not hard to manage. (Equivalent to 2 1/2 deep full sized frames) Easy to find queens. Easy on my back since I have them at waist or higher level. After the last round of mated queens are sold, I simply combine a few nucs together with a single queen in a modified deep 10 frame box. where they overwinter just fine.
In the spring I feed these hives well until most frames are packed with brood and feed, then distribute to the mini box's just like any split. Wait 15-24 hours (Basically overnight) and introduce a newly hatched marked Virgin directly. I've never had one not accepted as long as they are introduced within a few hours after hatching. I'll do a feed frame front and back with three decently filled brood frames in the center. By the time the first virgin is mated and laying those cells will be empty and ready to accept her eggs. I feed a pollen patty on top so no pollen frame is necessary. They are pretty self sufficient after that.
These are the singles I made up last year..hanging in the raspberry patch
I made up about 30 doubles for this spring in standard nuc woodenware.
30 of these will give me 60 mini deep mating nucs:
Just being stored inside until time to use it:
I used divided deeps last year too and they worked well too.
Last edited by Lauri; 02-27-2013 at 11:44 PM.
Here's my starter hive too. I started out with five frames in a ten frame box, using a follower board to keep them corralled. Fed them syrup and pollen patties. As I freshened this colony regularly with new frames of capped brood and young nurse bees, I did not have to take out empty frames..there were none! No reason to remove frames they had filled with stores, so I use a follower board to keep them crowded, but could expand the interior to fit my freshening or manipulations (Getting the graft frame in and out) They all stay on one side of the board and really never cross it if it is empty. They will cross it to get to a feeder though. Works very well. When I eventually filled it, I gave them a long deserved virgin and let them form a nice colony for overwintering. They were happy bees
I don't know why that one empty frame is in there..disregard that please.
Her is a box I brushed a few frames of bees into. I let it sit a few hours in warm weather and the older bees fly back to the old hives and scooped what was left into the mating nucs. If I was really picky, I'd run these bees through a queen excluder to remove any drones, but I had no problems this way.
Heres a photo of new 2012 virgin, just installed. Can't wait until spring! New ideas and all
Last edited by Lauri; 02-27-2013 at 11:00 PM.
That last picture is a virgin? That"s an 2013 virgin? Wouldn't say it much looks like one. Way to snaky and long IMO. If it is when was it hatched? Little early to be mating queens in Washington isn't it? Nice equipment BTW
Yellow paint, dude. That may or may not be a clue.
Confucius say:One must be observent when keeping of the bee
Was that Brother adam?
Or maybe OdFrank. He loves being drug into these posts!
Last edited by Lauri; 02-27-2013 at 09:40 PM.


text:
Gadget Geek's Guide to Beer
Get your weekly tech fix with these awesome beer gadgets.
From robots to brew kits, these are the gadgets you need if you're a beer lover.
Beer Robot
A couple of years ago at Middlesex University, a Heineken robot who pours the perfect glass of beer was developed and, no surprise, was a huge hit with anyone who came across the machine. All you need to do is load the robot with Heineken's mini keg, wave your hand in front of its sensors as it zips around the room, place your pint glass on its cup holder and let it pour you the perfect glass of beer. The robot made such a hit at the Kinetica Art fair in London, they now sell it for a cool $2,200 on their site. The price may seem high, but we can promise that you'll be the only one with a Dalek beer butler on your street. Buy your own here: Kinetica-museum.org
Price: $2,200
Specs: Battery life sensor, four-hour battery life, compatible with 5L Heineken mini keg
Octane 120 Pro Beer Arcade
Photo courtesy of: dreamarcades.com
If you don't live around one of those adult fun centers where you get to blow all your cash trying to win an inflatable sword while downing pint after pint, how could you not buy an Octane 120 Pro Beer Arcade for your home? Just as the site says, "(it) combines three things every gamer wants: classic arcade games, arcade-style racing, and a beer tap to get your favorite beverage without having to get out of the seat." With a full keg set up in the back, a beer tap right on the dash and a two-player control panel with built-in track ball, you may never go back to the couch again. The Octane 120 Pro can hold two five-gallon kegs or one half-barrel keg. In this case, happiness comes at the hefty price tag of $6,000. Buy your own here: dreamarcades.com
Price: $6,000
Specs: Adjustable steering wheel and seat, 2-player mode, 200 racing and arcade video games, full HD projector, PS3-compatible
Beer Savers
A little less thrilling, but a bit more innovative: these Beer Savers Silicone Rubber Bottle Caps will no doubt save us all a little bit of change. Designed to keep your beer fresh and safe, popping on one of these colorful bottle caps is a great alternative at the end of the night when you just can't bear the idea of finishing another drink. It's also great for those who home brew and need to keep the beer bottles clean and sterile before bottling! Buy your own here: amazon.com
Price: $3.45 (set of 6)
Specs: Dishwasher safe, reusable, fits standard beer bottle sizes
Brew Kit
Are all of these gadgets making you feel a little crafty? You can spend a ton of money on a full-size brew kit, but when it comes down to it, you probably won't make brewing your day job. Craft a Brew Starter Kits are great for people who are interested in making their own batch without breaking the bank, and they're fairly delicious too. There are a few kinds to choose from, but we really enjoy the American Pale Ale starter kit, which has all the gear you need to make one gallon of beer. Buy your own here: amazon.com
Price: $45
Specs: Everything you need to get brewing


text:
On the eve of a jury trial, a Suisun City man accused of a 2011 drive-by shooting that left one man dead and injured another accepted a plea deal on Wednesday in Solano County Superior Court.
Prosecutors believe Aaron J. Bragg, 19, fired a handgun from his vehicle into another vehicle on Canvasback Drive, striking Derico Hughes, 21, in the hand and James Taylor, 20, in the head. Three days after the Nov. 3, 2011, shooting, a decision was made by family members to remove Taylor from life support as he had no detectable brain activity.
On Thursday, before Judge Robert Bowers, Bragg entered no-contest pleas to voluntary manslaughter and assault with a firearm charges, along with enhancements for personal use of a firearm causing injury or death. In exchange for his plea, prosecutors dropped the murder and attempted-murder charges he had been facing.
Prosecutors believe that Hughes was driving his white Chevrolet Malibu on Canvasback Drive when a Pontiac Grand Am, driven by Bragg, pulled up alongside and opened fire. A second subject, Dominic R. Foster, 19, was also in the car with Bragg , but is not being prosecuted.
During a May preliminary hearing, Fairfield police Officer Pedro Arroyo, who was a Suisun City police detective at the time of the shooting, testified to witness statements made after the shooting.
Arroyo testified that an occupant of Hughes' vehicle eventually confessed to being present at the time of the shooting, despite leaving the scene along with at least one other occupant before police arrived.
According to the witness, Rashawn Jones, 19, of San Francisco, the occupants of the Malibu driven by Hughes had seen Bragg and Foster in the Grand Am on several occasions and the occupants of the two vehicles traded some menacing looks.
Arroyo also testified to statements that Foster made following the incident.
Foster told the detective that Bragg was upset because Hughes was following him around town that day. While Arroyo said that Foster gave a number of conflicting statements, he testified that Foster admitted that Bragg waited at a stop sign on Canvasback Drive for Hughes' vehicle to pull up. Bragg then pulled a revolver from his waistline and fired multiple shots into Hughes' vehicle.
Bowers indicated that the maximum sentence Bragg could face for his conviction was 25 years, four months in state prison; however, attorneys in the case agreed to a state prison sentence of 17 years.
Bowers ordered Bragg back at 8:30 a.m. on Feb. 27 for sentencing. He remains in Solano County Jail custody.
Follow Staff Writer Ryan Chalk at Twitter.com/RyanChalk1883.


text:
The bin catches the honey. Placing the frames in upside down causes them to drain out because of the natural UP angle of the cells (which would be DOWN) The one dish drainer (bottom) holds the frames between the plate slots. The second drainer (on top) keeps the frames from falling over.
Uncap the frames, put them in upside down, wait in a warm place. The honey flows out on its own.
One of the true unique pleasures of beekeeping regardless of whether you are a hobbyist, commercial or sideliner is getting to extract your hard earned honey crop when and if it becomes available. Everyone should be allowed to enjoy that experience once or twice as part of this hobby or profession. For me there is nothing more frustrating than trying to work with honey trying to crush, strain, chop, grind or whatever. It would appear that having to mess with honey in that regard just once would drive many people away from keeping bees for good. It would also appear to me that many, many, individuals would gladly (justify) and shell out a few bucks to buy a 2 frame, 9 frame or 20 frame extractor to assist them with that endeavor. After asking my wife to help me extract honey using a 4 frame hand cranked extractor for two years the fascination of that labor for her at least wore off quite rapidly. "So John" she asked one afternoon, "don't they make a machine with a motor to help you do this stuff"......to which I replied "well yes" ..perfect she said go buy one ! so I did.
"Tradition becomes our security, and when the mind is secure it is in decay".....Krishnamurti
I use a cement mixer!
http://OxaVap.com Your source for the ProVap 110
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Well this has turned into a very interesting conversation. I am planning on getting a warre hive so I want the wax and honey. That is why I was thinking a grinder to pulverize everything and make separation easier.
The press seems the way to go. It seems that you can make one. I could be real energy efficient (I use that term instead of lazy) and out an electric cylinder on it so I don't have to do any cranking myself.
I like all of the approaches that everyone has out on here. I will be checking them out over the next several months I am sure.
Wood is naturally antibacterial - like honey.
Concerning my post of my extractor-less extracting...
I'm very sorry, but I don't have a way of doing pictures at the moment.
Hmm, not even a newbie yet cause still looking for swarms that will stay with me.
But I was thinking, what about one of those old clothes wringers that you used to squeeze water from your clothes after you scrubbed them on the old scrub board. Have seen those things used for some other neat uses that were just as far from the original purpose as this is.
Now let it rip. LOL
It is easy to smash the comb with a potato masher or similar. The next step is to warm the honey,gently and let the wax float. Skim and repeat for a few days. Be patient, its do-able.
I have put broken comb chunks in a salad spinner. Decap first. Seems stupid,but works great!
Oh I think a meat grinder would work fabulously, just put what it churns out into mesh bag to strain...I am going to try it! I have a grinder that will blow through a moose lickety split. Just use a course plate.
I took a plastic 20L basket, drilled holes of 3,5mm on the bottom, put honeycomb into the basket and crashed it by a knife (you can try to "mince" it by a drill).
We're do you buy these extractors bill91943?
if you are going to make a press, do the whole box at a time, Weld a jig to sit a box in with a piece of all thread and a crank attached to a plate that just fits inside the box. set box in crank it down through a screen of some sorts and when you are done you just pull your empty box.


text:
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text:
How useful is scripting compared to programming?
Can someone tell me which is a good scripting language for exploiting websites? I know it has to be a web based language but everywhere I see perl and python.
I thought these were programming languages used to develop full on programs wereas scripting languages are not as large as programming languages


text:
Effects of 2 Initial Standard Antiretroviral Combinations Therapies on Lipid Metabolism (LIPOTAR-07)
The recruitment status of this study is unknown. The completion date has passed and the status has not been verified in more than two years.
Verified February 2013 by Hospital Clinic of Barcelona.
Recruitment status was: Active, not recruiting
Recruitment status was: Active, not recruiting
Juan A. Arnaiz
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Germans Trias i Pujol Hospital
Hospital Universitari Joan XXIII de Tarragona.
Hospitales Universitarios Virgen del Rocío
Information provided by (Responsible Party):
Juan A. Arnaiz, Hospital Clinic of Barcelona
ClinicalTrials.gov Identifier:
First received: September 23, 2008
Last updated: February 21, 2013
Last verified: February 2013
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
This study is an open-label, randomized, pilot comparison of the effects of either lopinavir/ritonavir or efavirenz in combination with tenofovir plus emtricitabine on cholesterol metabolism, mitochondrial functioning and immune response in 50 naive HIV patients after 48 weeks.
HIV Infections
Drug: Tenofovir + emtricitabine + efavirenz
Drug: Tenofovir + emtricitabine + lopinavir/ritonavir
Phase 4
|Study Type:
|Study Design:
|Allocation: Randomized
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|Effects of 2 Initial Standard Antiretroviral Combinations Therapies on Lipid Metabolism in ARV-naive HIV-infected Subjects
Resource links provided by NLM:
MedlinePlus related topics: HIV/AIDS
Drug Information available for: Emtricitabine Tenofovir Efavirenz Ritonavir Lopinavir Tenofovir Disoproxil FumarateU.S. FDA Resources
Further study details as provided by Hospital Clinic of Barcelona:
Primary Outcome Measures:
- Changes in total cholesterol and HDL and LDL fractions [ Time Frame: 48 weeks ]
|Estimated Enrollment:
|Study Start Date:
|September 2008
|Estimated Study Completion Date:
|July 2013
|Estimated Primary Completion Date:
|July 2013 (Final data collection date for primary outcome measure)
|Assigned Interventions
Active Comparator: 1
Tenofovir (TDF) + emtricitabine (FTC) + efavirenz (EFV)
Drug: Tenofovir + emtricitabine + efavirenz
Tenofovir 300 mg + emtricitabine 200 mg, (Truvada, Gilead Sciences)
+ Efavirenz 600 mg, (Sustiva, Bristol-Myers Squibb) once daily
Active Comparator: 2
Tenofovir (TDF) + emtricitabine (FTC) + lopinavir/ritonavir (LPV/RTV)
Drug: Tenofovir + emtricitabine + lopinavir/ritonavir
Tenofovir 300 mg + emtricitabine 200 mg, (Truvada, Gilead Sciences)QD Lopinavir/ritonavir 400 mg/100 mg, (Kaletra, Abbott) BID
|Ages Eligible for Study:
|18 Years and older (Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Chronic HIV-1 infection
- Age 18 or above
- Antiretroviral-naive
- Criteria for antiretroviral therapy in accordance with current guidelines
- Plasma LDL-cholesterol below 190 mg/dL
- Not receiving lipid-lowering agents
- Written informed consent
Exclusion Criteria:
- Use of phytosterol-enriched food previous month.
- Pregnancy or breastfeeding
- Cardiovascular disease
- Secondary Hypercholesterolemia
- Plasma creatinine above 1,2 mg/dL)
- Aminotransferases above 5 times ULN
- Current treatment for hepatitis C coinfection
- Diabetes mellitus (fasting glycemia > 124 mg/dL)
- Illegal drug use or alcohol abuse
- Active AIDS-defining opportunistic disease
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00759070
Please refer to this study by its ClinicalTrials.gov identifier: NCT00759070
|Hospital Germans Trias i Pujol
|Badalona, Barcelona, Spain, 08916
|Hospital de la Santa Creu i Sant Pau
|Barcelona, Spain, 08025
|Hospital Clinic
|Barcelona, Spain, 08036
|Hospital Universitario Virgen del Rocío
|Sevilla, Spain, 41013
|Hospital Joan XXIII
|Tarragona, Spain, 43007
Sponsors and Collaborators
Juan A. Arnaiz
Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Germans Trias i Pujol Hospital
Hospital Universitari Joan XXIII de Tarragona.
Hospitales Universitarios Virgen del Rocío
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by Hospital Clinic of Barcelona:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on May 25, 2017
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Egaña-Gorroño L, Martínez E, Domingo P, Loncà M, Escribà T, Fontdevila J, Vidal F, Negredo E, Gatell JM, Arnedo M. Differential subcutaneous adipose tissue gene expression patterns in a randomized clinical trial of efavirenz or lopinavir-ritonavir in antiretroviral-naive patients. Antimicrob Agents Chemother. 2014 Nov;58(11):6717-23. doi: 10.1128/AAC.03481-14. Epub 2014 Aug 25.
|Responsible Party:
|Juan A. Arnaiz, MD, PhD, Hospital Clinic of Barcelona
|ClinicalTrials.gov Identifier:
|NCT00759070 History of Changes
|Other Study ID Numbers:
EudraCT number: 2007-002698-29
|Study First Received:
|September 23, 2008
|Last Updated:
|February 21, 2013
Keywords provided by Hospital Clinic of Barcelona:
Treatment Naïve
Additional relevant MeSH terms:
HIV Infections
Lentivirus Infections
Retroviridae Infections
RNA Virus Infections
Virus Diseases
Sexually Transmitted Diseases, Viral
Sexually Transmitted Diseases
Immunologic Deficiency Syndromes
Immune System Diseases
HIV Protease Inhibitors
Protease Inhibitors
Enzyme Inhibitors
Molecular Mechanisms of Pharmacological Action
Anti-HIV Agents
Anti-Retroviral Agents
Antiviral Agents
Anti-Infective Agents
Cytochrome P-450 CYP3A Inhibitors
Cytochrome P-450 Enzyme Inhibitors
Reverse Transcriptase Inhibitors
Nucleic Acid Synthesis Inhibitors
Cytochrome P-450 CYP2C9 Inhibitors
Cytochrome P-450 CYP2C19 Inhibitors
Cytochrome P-450 CYP2B6 Inducers
Cytochrome P-450 Enzyme Inducers
ClinicalTrials.gov processed this record on May 25, 2017


text:
There are some proposed rule changes that will benefit the ladies who attempt the harder triple jumps. The Japanese federation has proposed that ladies be permitted to do 3A in the SP as the axel jump. Another rule change would raise the value of downgraded triples. Both of these changes would put Laura at a disadvantage, especially if she continues to double intended triples.
Mirai depends on callers and I still have some doubt about Oly tech callers. It's not that I support her National tech callers or want her to suffer from invisible URs that trained commentators miss in slow mo, which I find to be so nerdy. But the bottomline is that she is consistently called and the Oly was one of the very few events in which she was not called. We still need to see how well she fares next season.
It's the TECH TEAM that is rough on the URs, not the judges. But proposed new rules will lessen the penalty for URs considerably. The skater will no longer get the value of a double with additional -GOE. Instead, the base value of a URd triple will be less than a triple but greater than a double, and the GOE will be up to the judges. So even if Mao gets a UR on her 3A, she will get many more points than she is getting now. Mirai Nagasu will benefit as well.
In fact, Nagasu got 3 URs in her FS at Worlds. That cost her a medal. Under the new rules, she would have gotten an additional 3.5-4 points, which would have been enough to place her above Lepisto.
http://www.youtube.com/watch?v=ZmyUwtmch9w .She is still a terrific skater but she really needs to bring back those other jumps. It's almost embarrassing that the World Champion can't do a 3lz or a 3sal
Highly doubtful, especially with the rise of younger skaters (Murakami and Nagasu) and the veterans (Asada and maybe Kostner). I honestly think that her bronze was questionable, but I do congratulate her and hope that she works harder to maintain her momentum and stay on the podiums.
On that note, for Laura, now that she's a world medalist I think she needs to start working on TWO new programs every year, and not recycling one as she has done (and plans to do again for this coming season). I hate recycled programs, it so takes away from the excitement of the new season.
I am all for world champ ,OGM and all skaters to do a full set of triple jumps. I mentioned in another thread, I feel sad that 2 consecutive olys the lady OGM does not do a full set of triple jumps in their lp, in some ways that is more embarassing, afterall they are OGMs. ( and I am a huge Divakawa fan.) I believe Shizuka was eithr loopless or saless, and Yuna is absolutely loopless. I am not too optimistic that Mao will get a real lutz, but I sincerely hope she will get the 3sal. If she gets her 3sal, she will have almost a full set of triple jumps, which at least matches Shizuka and Yuna's total # of triple jumps, considering Shiz and Yuna are triple axel less
I actully like the final version of Bells at olsy and worlds. I will even say, unless someone in the future can interpret it better than Mao, with 2 triple axels to boot, I consider it as one of her signature pieces.Originally Posted by berrycute
I agree some Maofans are guilty of boxing her in one particular style. Gentle solo piano music is extremely difficult to skate to. And Mao is the best among current skaters to interpret that. I love Miki Ando to death, but I sincerely can not imagine Miki being able to interpret solo piano pieces. Prior to Mao, the only skaters that I think interpret do a great job with solo piano pieces are Buttle, and G and G (who can forget their moonlight sonata).
Last edited by rtureck; 04-11-2010 at 05:31 PM.
I thought her LP this year at Worlds is the best LP by a lady in recent memory. Mao presented a wide array of styles, jump contents and program layout. No one does it. I always look forward to seeing her new programs because they are always interesting.
Laura deserved her bronze because the other contenders made enough mistakes to take themselves out of contention. It's not like Laura came out of no where to win hers.
Miki bombed her SP pretty badly and was gifted with the flip that was an obvious URed.
Laura knows her problem, which is consistency. She'll work on it and hopefully become a better competitor in the years to come. Her speed is really impressive. She flew across the ice at Worlds. I even thought she was faster than Kostner.
Last edited by FlattFan; 04-11-2010 at 05:49 PM.


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Star Trek makes its network television debut. Given the cultural impact and enormous franchise spawned by the original Star Trek series, it's hard to believe that the show lasted just three seasons and was canceled by NBC in 1969 because of low ratings.
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Sept. 8, 1966: Liftoff for the Starship Enterprise
- September 8, 2011 |
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The shells of the PHX are 11-ply hybrid shells. The woods used are progressively harder from the center ply to the outer plies. The center ply is jatoba; this is a very hard wood' and it "anchors" the fundamental of the shell. Sandwiched on either side o...
The shells of the PHX are 11-ply hybrid shells. The woods used are progressively harder from the center ply to the outer plies. The center ply is jatoba; this is a very hard wood' and it "anchors" the fundamental of the shell. Sandwiched on either side of this is kapur. This wood is in the mahogany family and adds warmth to the sound of the drum. The inner and outer plies are maple, except in the case of drums using the optional burled ash outer ply. These drums use an outer half-ply each of maple and burled ash. Maple rounds out the tone adding high and mid frequencies to the shell.
Bearing edges
All drums have a 30° bearing edge, but each "family" of drums uses a different profile. Bass drums have a sharper edge cut toward the outer plies. This gives the bass drums attack and shortens the decay. Floor toms have a slightly rounded edge to give them a perfect balance of attack and sustain, making them very articulate at all dynamic levels. Toms have an even more rounded profile for warmth and sustain. This combination of shell composition and bearing edges makes PHX what many of our artists described as "the most musical drums [they] have ever played".
PHX uses redesigned versions of the Nouveau lug and YESS. The new lug mounts on a square hook rather than a round post. This keeps the tension rod in perfect vertical alignment and eliminates the need to use two hands while tuning the drum. We used the aluminum die-cast hoops made popular on our Absolute series for PHX. These hoops are very light but rigid, giving you the open, warm sound of a triple-flanged hoop and the accurate tuning of a die-cast hoop. Lugs and hoops are available in chrome or gold.
The new version of the YESS mounting system supports the drum at the top and bottom. The new version mounts the tom bracket onto a piece of the shell, and that wooden plate is isolated or shock-mounted using rubber grommets. A 3-piece fastening system is used to attach the new YESS to the shell, and the inside and outside fasteners do not touch. This system totally isolates the drum and allows the full tone to come through and maximizes sustain.
PHX is available with either maple and burled ash exterior plies, and with gold or chrome hardware. The finishes available on the maple outer ply are:
- Matte Natural
- Matte Black
- Polar White
- Cherry Sunburst
The finishes available on the burled ash are:
- Garnet Fade
- Sapphire Fade
- Turquoise Fade
- Textured Amber Sunburst
- Textured Black Sunburst
Audio & Video
The first models were produced at Yamaha's Niitsu factory in Hamamatsu, Japan, and later at our Miyatake factory as well. Many drummers who are familiar with Yamaha today believe that Sakae Rhythm was the original Yamaha production facility, but in fact production was started at Yamaha's own factories. Another common misconception is that our Air Seal System was developed at Sakae Rhythm, but it was actually developed and introduced right from the first models that were produced at our own factories. One of the earliest Yamaha drum brochures shows the original Yamaha production facility and describes Air Seal System technology, a Yamaha innovation that is a vital part of our identity as a drum manufacturer to this day.
Al Foster, who was touring Japan with the Miles Davis at the time, signed on to become a Yamaha endorser in 1972.
This was the turning point at which Yamaha drums began to be recognized as world-class instruments that satisfied the requirements of leading professionals in the field.
Shell mounting hardware had been different for each series and model up until this time. The system drum concept brought about the unification of all drum mounting hardware so that drums and hardware from any series could be mixed and combined as required.
Hexagonal rods and holder bases of the same specifications were used for all models, and the diameter of all stand hardware piping and holders was fixed at 22mm to allow total system fiexibility and freedom.
Although this approach is commonplace among today's drum manufacturers, it was a revolutionary concept at the time. Just one of Yamaha's many innovations that have become standards.
Another Yamaha hardware innovation worthy of mention is the hide-away boom stand. It was patented at the time, but as soon as the patent expired all of our competitors began copying our design. Today it has become another "standard" feature.
This continuously adjustable ball clamp made it possible to position toms up, down, left, or right, to any position required with one quick action. The current design allows toms to be flipped over for convenient bottom-head tuning ... a feature that is greatly appreciated by both drummers and drum technicians. Like the hexagonal mounting rod, the ball clamp has become a symbol of Yamaha hardware superiority.
This model featured 100% birch shells, one-piece lugs, and a gorgeous sprayed finish. Maple was the most popular material for drum shells at the time, following the trend set by jazz drums from the U.S.A. Through our own research related to pianos and wind instruments, we had realized that birch would be an ideal material for drum shells. We were also the first to apply piano finishing techniques to drums, eschewing the veneer covering that was common at the time. The full force of Yamaha technology was applied to the production of this landmark product.
The use of one-piece lugs to enhance the natural hardness of the birch shells resulted in a tight, well-defined sound that was enthusiastically adopted by many top artists of the day, including Steve Gadd and Cozy Powell. The sound was so well suited to recording that the YD9000 has become the most recorded drum set in history. The name was later changed to "Recording Custom," a model that is still widely used today.
Although there were concerns that a change from birch to maple shells might meet some resistance from users, Yamaha decided to introduce maple shells in order to accommodate changes in the music scene as well as evolving recording technology. From about the mid 80's, influenced by the emergence of fusion, drummers began demanding response and resonance that would suit the more elaborate phrasing used in that genre. Maple provided a bright, rapid response that was ideal, and by reducing the dimensions of parts that could dampen resonance as much as possible the natural shell resonance could come through with unrestricted tone. This led to the development of small, lightweight lugs, an extremely thin "vintage" finish, and the YESS (Yamaha Enhanced Sustain System) nodal mount for open, organic shell resonance.
The idea of using small lugs mounted so that they don't dampen shell resonance was quickly adopted by other manufacturers as well.
Throughout the 90's Yamaha maintained an active, aggressive approach to product development. The Stage Custom model introduced in 1996 was one result. This series offered the same type of birch shell that was being used in the popular RC series, with the same one-piece lugs and a beautiful sprayed finish, at a surprisingly affordable price.
The Maple Absolute series took the philosophy of achieving the richest possible shell resonance to the next level. In the same year new beech shells were introduced alongside the existing birch shells in the Absolute series.
At around this time Yamaha was collaborating with top-level artists from all around the world in developing a range of exciting new products such as the Hipgig and JR drum kits, the Musashi snare, and the Subkick low-frequency capture device.
Although other manufacturers had avoided using oak in drums because it is extremely difficult to work with, Yamaha succeeded in forming this very hard wood into drum shells using our Air Seal System technology. The result was impressive response and huge bass that has made this model a standard in the Yamaha lineup.
Pushing Yamaha finishing technology to the limit, a lineup of almost 50 colors was developed for the Absolute series. The revolutionary detachable Nouveau lugs were developed to further reduce shell damping while at the same time making head replacement easier than ever.
Years of drum manufacturing experience and accumulated technological know-how, plus in-depth reassessment of every critical aspect of drum design and production, all came together to bring about a profound evolution in the form of the hybrid shell: the key to delivering unprecedented tone and power. The lugs took another evolutionary leap too. Going beyond the concept of minimizing shell damping, lug design and mounting now plays an active role in creating and controlling the sound of the drums by suppressing unwanted harmonics. Tom mounting has advanced as well, resulting in unprecedented tone and consistent playability.
The YESS2 mount and new hook lugs developed for the PHX series have now been implemented in the Absolute series as well, contributing to even clearer, richer sound. A newly developed textured finish has been applied in the Rock Tour series, significantly enhancing visual impact. Kapur was discovered and used for its excellent tonal qualities in the PHX series drums and is now used as the sole tone wood for the sound of the Club Custom drums.
Artist Who Play PHX
|Tommy Aldridge
|Dave Weckl
|Drum Legend
|Gorden Campbell
|American Idol Live/ Phillip Phillips
|Teddy Campbell
|The Tonight Show With Jay Leno
|Paul Leim
|Nashville Studio
|David Garibaldi
|Tower Of Power
|Kendrick Scott
|Terence Blanchard
|Sonny Emory
|Bruce Hornsby/Bette Midler
|Anton Fig
|Late Show With David Letterman
|Mike Shapiro
|Sergio Mendez
|Tommy Igoe
|Birdland Big Band
|Ralph Humphrey
|Dancing With The Stars
|Vince Wilburn Jr.
|Mark Dalzell
Design/Architecture Detail
|New Hook Lug
|Hybrid Shell (Jatoba+Kapur+Maple)
|Clear Ambassador
|Clear Ambassador
|PS3 SW without Hole
|PS3 Clear
Optional Accessories
Online Help
Reviewed by 1 customer
- Great And Flexible Drums
- The Best Sound
- none
Best Uses
- Live gigs
- Recording
Comments about Yamaha phx_turquoise_fade:
I play in a band that plays small clubs and large events (1,00-3,500) and the drums are great. In clubs, no mics required and they sound perfect! In large events, the sound guys are blown away by the drums and how great they sound. I have been playing for 30 years and always wanted the best... and finally took the plunge and got them. Yes they were expensive, but sometimes you get what you pay for... and in this case I certainly did!
- Was this a gift?:
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How cute. I love some of the fabrics you have chosen.
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How cute. I love some of the fabrics you have chosen.
You made good use of a rainy day! Nice job!
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Totally cute.
Dance like no one is watching
Very very cute. Love your fabrics.
Love the fabrics! Nice job!
Once upon a time~
There was enough time~DD
So very cute - love the fabrics. I can sympathize with rainy weather, as we've had a lot lately.
What a sweet baby quilt. Love the fabric you used. peace
no act of kindness, no matter how small, is ever wasted. Aesop
So cute and I love the fabrics with the chickens and sheep!!


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Town Square
Next Supreme Court Nominee
Original post made by Paul Losch, a resident of Palo Alto, on Apr 20, 2010
Process: it appears that Obama is trying to work with the Senate leadership and the Judiciary Committee leadership, according to news article that have come out of late.
I contrast this with W's buffoon announcement that he would nominate Harriett Meyers, a Texas crony of his. Even the GOP Senators pushed back on that one, and rightly so.
Give Obama credit for using a more deliberative process for nominating someone to this great deliberative body, the US Supreme Court.
Substantive observation: when is it qualifications and when is it legal opinions? Nominating judges at all levels is part of the political process, make no mistake about that.
When someone is viewed as qualified for such a nomination, should a Senator vote up or down based on prior opinions a nominee has had?
What about those who have been nominated for a position on a court who has a track record outside the Court, such as academia or political elective office?
I view the current US Senate, especially on the GOP side, as looking to play "Gotcha" on nominees for the Supreme Court and for other judicial levels.
We need good, no--excellent--people on all the benches. I cannot tell right now if the Senate is able to do that.
Comments (29)
a resident of Midtown
on Apr 20, 2010 at 5:07 pm
Two words for you: Robert Bork
a resident of Midtown
on Apr 20, 2010 at 6:58 pm
Another consideration, in addition to competence, will be religion.
Currently 6 justices are of the Catholic Faith and two of the Jewish Faith with the only Protestant retiring.
As Protestants are the majority faith in the USA this will be an important issue-- Mormons fall under the Protestant category and are about 2-3% of the population and increasing rapidly,---- Muslims are also 2-3% of the population and also increasing rapidly.
It is amazing that Catholics and Jews, who have both been historically marginalized in the US, have come to dominate the Court way beyond their demographic proportion in the population.
Obama should also reach outside of lawyers and politicians to appoint someone who has had to make a payroll, run a business and create wealth-- someone like Bill Gates, John Chambers ( who has a law degree ) , Meg Whitman etc-- such a choice will be a game changer.
I believe all three are Protestant Christians.
a resident of Midtown
on Apr 23, 2010 at 6:44 am
Walter_E_Wallis is a registered user.
Hey, if Obama nominated Sarah Palin he could remove one competitor from the next election.
a resident of Evergreen Park
on May 3, 2010 at 5:16 pm
Hey! And she probably knows something about the law. She was probably able to see a courthouse from the Alaska governor's offices - when she was governor.
a resident of Midtown
on May 3, 2010 at 7:15 pm
A Supreme Court composed entirely of Catholics and Jews will not work for a predominantly Protestant Christian nation.
An Asian Protestant Christian the best choice--
Professor John Choon Yoo
fits the bill,Web Link
"Yoo emigrated with his parents from South Korea to the United States as an infant.
He grew up in Philadelphia, Pennsylvania, graduating from the Episcopal Academy in 1985.
He earned a B.A. degree summa cum laude in American history from Harvard University in 1989 and a J.D. from Yale Law School in 1992. Yoo clerked for D.C. Circuit Judge Laurence H. Silberman and then for United States Supreme Court Justice Clarence Thomas.
From 1995 to 1996, he was general counsel for the Senate Judiciary Committee.
Yoo is an active member of the Federalist Society.
He is married to Elsa Arnett, the daughter of Pulitzer Prize-winning journalist Peter Arnett."
a resident of Charleston Meadows
on May 3, 2010 at 8:23 pm
Sharon -
"It is amazing that Catholics and Jews, who have both been historically marginalized in the US, have come to dominate the Court way beyond their demographic proportion in the population."
It is not amazing. Their culture includes a strong focus on education, and both religions are steeped in deep philosophical and legal thinking. Add the constant exposure to current and historical argumentation from a young age. This allows development of legal and judging competence.
Tiger golfed from age two; it is not amazing that he's very good at the game.
a resident of Midtown
on May 3, 2010 at 8:43 pm
Interesting question. JFK was challenged for his allegiance, Pope or US but he did not have have dual citizenship nor automatic dual citizenship, anyone in the the world has the right of return to Israel which makes some people uncomfortable-- not me, we judge people on their character, actions and statements not ethnicity.
However, as 86% of Americans declare themselves as Christian-- the majority as Protestant, 2% as Jewish, 2% as Muslim and as the SCOTUS deals with many matters of church and state we need some balance-- a Protestant makes sense but a Muslim looks likely --given demographics and balance
We still like Yoo as a candidate-- competent, Christian and Asian.
a resident of Midtown
on May 3, 2010 at 9:14 pm
anyone of the Jewish faith has automatic dual citizenship, that used to be the case for those who had Irish, German parents etc-- probably still is--
we need a SCOTUS that has at least one Protestant American Christian on it, maybe a Mormon, but it should not be just Catholic and Jewish-- that is not the face of America-- it will loose credibility and that is serious
a resident of Midtown
on May 4, 2010 at 7:43 am
Sharon's comments border on the ridiculous. Her choice of John Yoo for the Supreme Court is solely put forward,not because she actually thinks that he is fit for service on the court,but to push buttons. Typical Sharon speak.
a resident of Midtown
on May 4, 2010 at 5:03 pm
We should have a good, solid atheist for the Court-someone who will be objective rather than follow religious mysticism of what ever ilk.
a resident of Midtown
on May 7, 2010 at 10:29 am
The buzz is that President Obama is ready to nominate Elana Kagan to the Supreme Court, probably by Monday.
Meanwhile, Paul Campos writes:Web Link
"Yesterday, I read everything Elena Kagan has ever published.
It didn't take long. . . . She's published very little academic scholarship—three law review articles, along with a couple of shorter essays and two brief book reviews. . . .
If Kagan is a brilliant legal scholar, the evidence must be lurking somewhere other than in her publications.
Kagan's scholarly writings are lifeless, dull, and eminently forgettable.
They are, on the whole, cautious academic exercises in the sort of banal on-the-other-handing whose prime virtue is that it's unlikely to offend anyone in a position of power."
It sound like Harriet Miers all over again---
a resident of Midtown
on May 7, 2010 at 11:21 am
Seems that earlier on this thread Sharon wrote:
"Obama should also reach outside of lawyers and politicians to appoint someone who has had to make a payroll, run a business and create wealth-- someone like Bill Gates, John Chambers ( who has a law degree ) , Meg Whitman etc-- such a choice will be a game changer."
Sharon suggested appointing someone who is not a "legal scholar"--now she is claiming that Ms Kagan is not fit because she is not a "legal scholar". So what do you want, Sharon?
Sounds to me like Sharon is going on the offensive again like she did when Obama nominated Sotomayor. You can go back and read Sharon's comments on this forum--they are part of the record now.
You will see that Ms Sotomayor was the target of constant denigration, insults and the questioning of her credentials by Sharon. Looks like we are gearing up for a repeat here. The only problem really with these nominees is that Obama is picking them.
a resident of Midtown
on May 9, 2010 at 8:38 pm
Kagan has never been a judge.
She has spent very little time as an advocate.
Her exposure to the judicial process is thus largely academic.
She banned US Military recruiters from Harvard Law.
What then is her qualification-- diversity?--empathy?
"Diversity" on the Supreme Court may be a fine thing on annual photo day.
It makes a pretty picture.
But diversity of views on the Constitution?
If it means some justices who get the Constitution badly wrong all the time? No, thanks.
a resident of Barron Park
on May 9, 2010 at 10:55 pm
"If it means some justices who get the Constitution badly wrong all the time?"
We're already there. Just think of the ideologues: Roberts, Scalia, Thomas, and Alito.
a resident of Midtown
on May 10, 2010 at 7:13 am
Did not take long, as expected, for Sharon to launch an attack on Obama's choice for the Supreme Court.
Sharon states:
"Kagan has never been a judge.
She has spent very little time as an advocate.
Her exposure to the judicial process is thus largely academic."
Why is that necessarily bad. Seems to me that earlier in this thread, Sharon was advocating appointing someone who was not a legal scholar to sit on the Court.
What is the problem now? Oh, I know, it is Obama's choice.
a resident of Palo Alto
on May 10, 2010 at 8:46 am
Paul Losch is a registered user.
There is an aphorism that my lawyer friends have shared with me:
The best law students become law school professors
The average law students become judges
The rest make all the money
a resident of Midtown
on May 10, 2010 at 8:53 am
Sharon states:
"She banned US Military recruiters from Harvard Law."
Let's look at this is more detail:
Web Link
"REALITY: Kagan consistently followed the law, and Harvard students had access to military recruiters during her entire tenure as dean. Throughout Kagan's tenure as dean, Harvard law students had access to military recruiters -- either through Harvard's Office of Career Services or through the Harvard Law School Veterans Association. Moreover, Kagan consistently followed existing law regarding access to military recruiters. Kagan briefly restricted (but did not eliminate) access to recruiters only after the U.S Court of Appeals for the 3rd Circuit ruled that law schools could do so. "
Seems like Sharon's post is a bit of an exaggeration. Surprised?
a resident of Midtown
on May 10, 2010 at 10:18 am
@ Paul
As you know there is an aphorism that is applied to all professions
-- Those who can do--Those who can't Teach--
Re Kagan -- she will be learning to be a judge "on the job"-- not a good idea--
"Perhaps an analogy to the medical profession is apposite.
Lots of very bright new physicians become interns and then spend several years as residents developing their qualifications for medical specialties.
Some become dermatologists, some become brain surgeons, and some become psychiatrists.
They are all physicians and presumably have the necessary experience to deal with medical conditions within their specialties.
However, it would be unreasonable and unfair to expect a dermatologist to diagnose and treat a brain tumor or a psychiatrist to remove an inflamed appendix.
OK, maybe, in an emergency and lacking any alternative; otherwise, it would be rather rather stupid.Web Link
a resident of Midtown
on May 10, 2010 at 10:30 am
"Re Kagan -- she will be learning to be a judge "on the job"-- not a good idea--"
So why, Sharon, did you earlier on this thread say that Obama should reach outside of lawyers and politicians. You stated it would be a "game changer". Surely those people would learn to be a judge "on the job".
What is the problem now?
a resident of Midtown
on May 10, 2010 at 6:32 pm
A SCOTUS candidate could be
1/ A CEO who has built a multi billion dollar business-- like Chambers @ Cisco
2/ A politician that is a governor who led a major state, built wealth, met budgets and payroles
3/ A Judge, who shows excellence and has a public judicial record
Kagan is non of these-- she is an administrator and a bureaucrat
She has published nothing of significance, she is anti US Military--
She may be a competent administrator of diversity and empathy-- the first HR SCOTUS candidate.
She is underwhelming and damned by faint praise from everyone, left and right.
a resident of Midtown
on May 10, 2010 at 8:57 pm
Typo correction--
2/ A politician WHO is/ was a governor who leads/ led a major state, built wealth, met budgets and payrolls
a resident of Midtown
on May 11, 2010 at 6:14 am
Sharon continues her assault on the latest Obama choice for the Supreme Court. She claims that a CEO or a politician with no judicial experience (and would not even have to be a lawyer) would qualify or a judge who "shows excellence and has a public judicial record".
Then she disqualifies Kagan by claiming that she has not done anything of significance. Would then Clarnece Thomas be on the court according to these requirements? Why would someone who is not evena lawyer be more qualified than Kagan?
She also repeats the myth regarding Kagan and the US military.
Get ready for a long summer of Kagan bashing
a resident of Midtown
on May 12, 2010 at 7:47 pm
As Kagan--
1/ does not have a judicial record--- she was never a judge
2/ does not case records, she was never a prosecutor nor a defense litigator
2/does not have a publication record-- she was just an administrator @ Harvard Law
We need to see the records of her brief work during the Clinton administration to evaluate the competence of the first HR candidate for SCOTUS
We hope the Clinton library cooperates-- in the best interests of the American people
a resident of Midtown
on May 12, 2010 at 8:38 pm
[Post removed by Palo Alto Online staff.]
a resident of Midtown
on May 13, 2010 at 6:09 am
Earl Warren and William rehnquist were not judges before being appointed to the Supreme Court. Sharon previously advocated appointing someone who is not even a lawyer or a politician and said they could learn on the job--so why does it matter that Kagan has no case or publication records?
The "rejecting US soldiers" lie is a myth--there is no truth to it. The issue deals with military recruiters and the "don't ask, don't tell" policy. If Sharon wants to make an issue of that , then maybe she should stick to the facts of the matter.
[Portion removed by Palo Alto Online staff.]
a resident of Midtown
on May 13, 2010 at 8:46 pm
[Post removed by Palo Alto Online staff.]
a resident of Midtown
on May 14, 2010 at 6:31 am
[Post removed by Palo Alto Online staff.]
a resident of Meadow Park
on Aug 6, 2010 at 6:46 am
Well, congrats "Progressives". You have another one on the SCOTUS. Kagan was approved, by all Dems, no Repubs. I never even bothered wasting my time on posting on her, it was a done deal the day she was appointed. ( the lemmings' leaders are in charge)
Remember this Palo Alto, and watch her votes over the next 40-50 years she is on the bench.
Americans are singularly uninformed about the power of the SCOTUS. It is a pity. I recommend reading "Men in Black" by Mark Levin. Recall the movie by the same name..and yes there were women in black also in the movie and on the SCOTUS, but for you literal minded, recall the context.
Web Link
Above is a link to a Rasmussen poll that says 86% of Americans believe there should be limits on what the Federal Government can do..but this lovely new Supreme actually can't even agree that the Fed Government does not have the right to tell you what to eat.. Below is a link to her answer to the simple question about if the Feds have the right to tell you what to eat.
Web Link
Either she is ignorant and inarticulate ( both parts of this sentence I support) or a rabid anti-Constitutionalist ( which I also believe..you know..go by what "feels dumb or smart", not the Constitution).
Running a law school means nothing about her ability to know and apply the Constitution. I have seen this multiple times as "support" for her. Ok, then I challenge any of you to go for surgery to an MD who has done nothing but teach or run a Medical School, except for one year of surgery, in her career. ....
But that is the thinking of our Dems now.
We said the single biggest threat to our land by this POTUS was going to be the Supreme Court packing, and here we are. Stuck now with 2 full-fledged ..whatever you want to call them..on our SCOTUS. The only good news is that they are just going to keep voting the way their predecessors did, so no change there.
And our wimpy Repubs didn't have the cojones to pull the filibuster back on the Dems like they did to our nominees because WE follow the Constitution ( it is, in fact, unconstitutional to filibuster a Judicial nominee, a fact which escapes Democrats every time they do it)..
At the very least our Repubs should have filibustered ...it may have at least brought the act to light and prevented it from happening when WE bring forth a nominee.
Americans have short memories ( 9/11 is a great example). But Conservativ/Libertarians don't.
We are going to take this country back, and we are not going to let our electeds regress into full elitist government power again ( like the ones of 1994 did).. The power of the internet is immense.
a resident of Midtown
on Aug 6, 2010 at 6:56 am
"You have another one on the SCOTUS. Kagan was approved, by all Dems, no Repubs. I never even bothered wasting my time on posting on her, it was a done deal the day she was appointed. "
There is no point in reading the rest of your diatribe when you start of with a blatant lie.
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Just recieved 15 Screen Bottom Boards they are in excellent condition and the wood is pretty good quality. Josh Cormack was quick in sending and very helpful via email.
These SBB are way better than brushy moutains, those would crack when I nailed them to the hive bodies. Cormacks are alot cheaper than most commerical sellers and are of good quality. I reccomend them.


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Discussion in 'March 2009' started by Dlev59, Feb 26, 2009.
I love that they are trying out there! Great win for the Pistons!
MC will be on ESPN's First Take today. I will count how many times he say "They Good".
AI out, Curry back in his comfort zone taking a page from the Flip book and overplaying the starters. Still, it's only 20 games or so and who knows what might happen. I notice that I'm having real problems getting a handle on Stuckey's game. He seems out of control to me, but comes up with some pretty good games, like last night. I could have sworn he had more than three turnovers. At least the games are back to fun to watch.
I find your avatar 's lack of vision disturrrrrbing !!
Its going to be a big test for AI . If he handles it well and Curry manages it right ( hopefully ) then it can actually boost his career - be a real team player. Take a que from Rip and get it done. Even Kevin McHale came off the bench at one time. Lot of great players have at one time or another. I have to believe that AI off the bench will be a better option than Will Bynum - just saying. But it has to be done right. I heard something on ESPN that the Nuggets have not won at the Palace since 1995. At least we are keeping that streak alive.
I always wondered something....How do u pronounce a word that no one else can hear? lol
I really dont think we EVER had SWAGGER. I believe the right word is CONCIET. The Celts, Lakers, Pistons and Bulls had SWAGGER. I believe we had 3 guys that hid behind Ben Wallace and when he left, they tried to yell at you from behind a closed door(see the Kid and Play scene in House Party or the taunting scene in THE HOLY GRAIL). But what we have seen the last 3 games is if we just shut up and play hard, we will win games. In the Army, chemistry builds confidence. And its hard to trust the 'new guy' in any form as quickly as we were made to trust Iverson. He will NEVER go along with this bench thing. As the old knight SIR TOM said to the 3Stooges..."HEED MY WARNING!!"
Id like to stay 6th. We have Orlando's number and if the Celts finish 2nd, I like our chances BETTER since they got Marbury.
I agree. Everytime I hear an announcer talking about the swagger this team had during that long glorious run, I wonder where I was. I just don't remember seeing it. At least the way I saw it with the teams HQ lists. This team always seemed to have more of CB's mayor personality than the hard-hearted-I'll-crush-you-in-the-dirt of those other teams. No doubt, CB and the others would stick the knife in and twist, but would smile at you afterwards and take you to dinner. They always seemed more politician than buccaneer to me too.
Remember the ovations Vinnie and Horn got? it was teary!!! Tripucka and Dantley got nice ones, too.
Stuckey = 2nd year guard from Eastern Washington!! Not exactly te Big West, Pac10, Acc, etc. Give him time....... or else.
not sure if you should say 5th.... heck at this point 6th might be the sweet spot for us, since the magic can't seem to find a way to beat us, we match up better against them then we do atlanta.
back when i played, I would stick a knife in you and twist AS i was goin in for a layup!! THATS swagger!
Nah, that's just playing hard. Swagger is what happens next - wiping the blood from your knife on their shirt as you go back up court - now that's some swaggering.
i lika da way ur brain thinks!
The whole overplaying the starters implies that we expect to go deep into the playoffs. This team needs to do what it can to win now...unless we want to tank and get a better seat in the lottery.
Or that you expect the team to be substantially reconfigured next year and there is more long term value is getting other players experience than in winning a few extra games in what is a meaningless season. But I don't disagree, it's only 20 games, may as well try to make a run and see if you get lucky.
What about some type of strategy where we send our scrubs in to agitate our opponents stars in the playoffs? The ultimate goal would be dual suspensions, like Herrmann out 5 games for punching KG. KG out 10 games for pulling Herrmann's hair in response. That way we don't have to rely on lucky injuries.
I don't think you come off the lucky injury strategy until it's proven not to work. Why trash a good thing?
I think the league might be on to us. And they have mob connections through Donaghy. If we keep this up, there might be some Jeff Gillooly action coming our way.
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For those that missed it, you can read our intern Emily Wienberg's Ragan's PR Daily blog on "Top 5 tips for PR interns—from an intern" here.
An excerpt:
"Eat lunch with your co-workers.
It's so simple, but many interns may not realize how important it is to connect with co-workers on a casual level. Taking a half-hour break during the day is necessary, so why not spend it with people who can offer advice and share stories about the industry you're interested in?"
Tweet us your advice for interns!


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- About Homelessness
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Economy Byte: Working Poor at Higher Risk for Homelessness
December 8, 2010
Brief on the working poor
Interactive state-by-state map
Newsflash: the working poor are having an especially tough time in this recession.
Shocked yet? Probably not.
But the picture is more textured and nuanced than you might imagine.
For the second installment of our "Economy Bytes" series, the Alliance's Homelessness Research Institute focused on a population that is struggling to weather the "Great Recession" – the working poor.
In short, we found that the working poor population is more likely to experience risk factors for homelessness than the general working population. And a lot of that is because they've been disproportionately affected by elements of this recession.
What do we mean? Okay, so we looked at three elements: severe housing cost burden, doubled up housing situations, and income.
And we found that – although people from different income brackets experience severe housing cost burden, doubled up housing situation, and reduced income – the working poor are more likely to experience these factors and experience them more acutely.
- Severe housing cost burden: In 2008, 37.6 percent of the working poor population spent more than 50 percent of their monthly income on rent compared to just 3.8 percent of the general working population.
- Doubled up: In 2008, an estimated 7.8 percent of the working poor population was doubled up with family or friends as compared to less than 6.5 percent of the general working population.
- Income/workforce: On average, the working poor population works 46.2 weeks per yearcompared to the general working population's 49.1 weeks per year. Moreover, the working poor population are also employed in more volatile industries and earn less per hour – industry average of $12.78 per hour compared with average private sector earnings of $21.62 per hour – than the average working person.
Each of these factors – and the culmination of them, certainly – are all risk factors for homelessness and, as the data show, common experiences among working poor people.
It's not pretty news but news nonetheless. To read the full report, please visit our website and while you're crusing, take a peek at our interactive map to see how your state stacks up.


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When you crap a massive log of shit the day after Christmas that percolated in your colon from Christmas dinner. These Yule log shits can take hours to pass due to the fact they are the size of a Chipoltle burrito. Often contains: ham, mashed potatoes, apple pie, gingerbread men, dinner rolls and other starchy/fatty drunk food.
My ass is covered in hemorrhoids from giving birth to the biggest yule log shit of my life. I was in labor for like 3 hours.


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Cosy Apartment near Vatican City
Size75 m²
Floor No.6(with elevator)
- Family/child friendly
- Internet/WiFi
- Kitchen
- Air conditioning
- Washer/dryer
- Elevator in building
- Balcony/terrace
Accommodation summary
|via Ennio Quirino Visconti, 00193 Roma, Italy
|Property type
|Property ID
Each of the bedrooms feature a comfortable double bed and ample storage spaces. The living area includes a mezzanine, and guests will find an espresso maker in the compact kitchenette. The colourful bathroom contains a shower, and complimentary toiletries are provided.
Excellently located for public transport, Lepanto Metro Station is only a 10-minute walk away. The nearest bus stops can be reached within just a few steps, and provide regular access to Rome's major attractions. The Colosseum can also be reached within just a 25-minute walk.
Piazza del Popolo Square, Sant'Angelo Castle and the Trevi Fountain can all be reached within a 15-minute walk. The Spanish Steps,and the Pantheon are also just 15 minutes away on foot.
House rules
|Weekly rate for 1 guest
|Price for > 1 guests
|$ 5 US per guest/night extra
|Maximum nights
|3 months
|Check-in after
|Check-in before
|On arrangement
|Check-out before
|Cancellation Policy
Reviews of this property
la Terazza fiorita is a wonderfull place to stay in Roma for a week. Its spacious and well equiped. Even in februari breakfast or lunch on the terazza is wonderfull, you can see the villa Medici, the church above the Scale di Spagna but also the San Pietro. Public transport is at a convenient distance and its in a lively and quite neigbourhood.
This is the Best. I have stayed in quite a number of Wimdu properties but this must be the best one. It is a beautiful modern bright spacious apartment which has everything including a stunning balcony and view across the Tiber into the trees and towards the Villa Borghese park, Villa Medici palazzo, and the Trinita des Monti church above the Spanish Steps. This view is hypnotic and I found it almost impossible in the two months I stayed here to tear myself away from the balcony during the daytime. I stayed for all of November and almost all of December, in bright warm sunshine during the day, with only one morning of rain in all that time. From mid-morning to mid-afternoon, the balcony was a warm irresistible haven, with a marvellous Rome view, and gorgeous sunsets. The inside of the apartment is lovely and has everything you could need, from wardrobe space to kitchen area and equipment. The bedrooms are spacious and the beds comfortable, The bathroom is also spacious and beautifully tiled. The apartment is quiet, perfectly quiet in the evening and night time, during the day there is a rumour of traffic to remind you that you are in the heart of a great city, but the traffic is never invasive, believe me as I do not like any noise. Communication with Chiara was great, and Livio, who welcomed me to the apartment, was always available at a moment's notice quite literally, they are attentive and caring hosts. The area is also great with an abundance of restaurants and stores along the shopping artery of Cola di Rienzo, and just 15 to 20 minutes of a leisurely stroll to the historic centre or to St Peter's. I can recommend this apartment without reservation and if I can ever return to Rome for even a longer period this is where I would choose to stay! If you are going to stay here you should just consider yourselves lucky! Enjoy!
Hi, me and my dad stayed in "La Fiorita" in the beginning of august. Livio met us at the appointed time in front of the appartment and showed it to us. The appartment fullfilled our expectations and even more than that. Two spacious bedrooms, a well equipped kitchen, a lovely bathroom with wonderful shampoo for hair and body. Lots of towels provided, bathropes and slippers, But the top of it all was the lovely terrace on the 6th floor with great wievs towards the spanish steps. The Apartment was located centrally just a short walk from the historical center. We would definitely stay here again and will not hesitate to recommend this cozy appartment to family and friends. Oh, and thanks for the lovely applepie! Thanks to Livio and Chiara for offering this lovely appartment to us. Love from Peter and Ib.
We were greeted very friendly and comprehensive information about everything in the house. In addition there was a lot of valuable tips about bus services and attractions and good material (map etc.). The homemade cakes on the terrace on arrival was a dream. Better it is not .. thank you.
Wir wurden sehr freundlich empfangen und umfassend über alles im Haus informiert . Dazu gab es viele wertvolle Tipps zu Busverbindungen und Sehenswürdigkeiten und gutes Material (Stadtplan etc.).Der selbst gebackene Kuchen auf der Terasse zur Begrüßung war ein Traum. Besser geht es nicht.. Danke .
If you are thinking of going to Rome, the best option certainly is this apartment. Super cozy with stunning views and all the details that you can imagine. Chiara and her father a lovely and very helpful people.
Without a doubt the best accommodation we've been to Rome.
Si estáis pensando ir a Roma, la mejor opción, sin duda, es este apartamento. Súper acogedor, con unas vistas impresionantes y con todos los detalles que os podáis imaginar. Chiara y su padre unas personas encantadoras y muy serviciales.
Sin lugar a duda el mejor alojamiento en el que hemos estado en Roma.
Rome again in this apartment - best location, best equipment, best host - just super. We would love to come back and say Chiara and her family thank you very much.
Rom immer wieder in dieser Wohnung - beste Lage, beste Ausstattung, beste Gastgeber - einfach super. Wir kommen gern wieder und sagen Chiara und ihrer Familie herzlichen Dank.
Chiara and Livio made this journey perfect. As the flat is very well located we didn't have to use the public transport. Every sights can be visited walking. The flat itself is clean and offer a terrace where we cn get the sun from the morning. On the top Chiara and Livio and extremely friendly and did a lot to share some tips about Roma. Thanks a lot Livio.
Juliette, Anna and Didier
Excellent apartment, centrally located, good guidance and reception by host.
Prima appartement, centraal gelegen, goede begeleiding en ontvangst door gastheer.
My family and I myself spent a wonderful long weekend in Rome. We were warmly welcomed by our host. We received a perfect information package about the surrounding area. The rooms are bright and due to airconditions in living and bedrooms even a stay in hot summertime is easy to stand. From the balcony we had a free view over the roofs of Rome towards the church at the upper end of the "spanish steps". The appartment is perfectly located close to the Piazza del Popolo and due to that a very good starting point for exploring ancient Rome as well as for shopping Tours. On top of that we could enjoy an exklusive guided tour through Rome by nicht by our hosts father Livio. We will keep this stay in our mind - thanks to Chiara & Livio
Lovely apartment! Hospitable, friendly, attentive hosts? The apartment has everything that you may need! The location is great. We have not had to use the passes that are purchased in advance, as to all the attractions are within walking distance! Thank you, Chiara. And mom and dad thank you very much for your attention.
Прекрасные апартаменты! Гостеприимные, доброжелательные, внимательные хозяева! В квартире есть все, что только может вам понадобиться! Расположение отличное. Нам не пришлось воспользоваться проездными, которые купили заранее, поскольку до всех достопримечательностей можно дойти пешком! Спасибо, Chiara. А также маме и папе большое спасибо за внимание.
- Quality assured accommodation
- Every host is verified by telephone
- Secure payment via SSL encryption


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Discussion in 'Pistons and NBA' started by roscoe36, Dec 6, 2006.
Denton: Armstrong Ready For Next Phase Darrell Armstrong Statistics - Basketball-Reference.com
Wow, sounds like DA has a pretty bright future ahead of him. Pasting the newspaper article onto his cellphone so he would see it all the time sounds like something Jordan would have done.
There'd probably be better coffee in the lockerroom, too.
The coaching carousel usually goes Hardass Player's coach Hardass Player's coach as eventually one style or approach loses the interest of a player group.
free the armstrong!
Is the consensus here that Laimbeer wouldn't be any good? I'm not trying to be a homer and I haven't really paid attention to his coaching style with the Shock.
I'm hesitant about Laimbeer because I can't tell where the homerism ends and the qualified coach begins. We all have fond memories of Bill the butt kicker as a player, but this is an older, fatter, richer and wiser Bill. It's also a man who is now removed from broadcasting and has not worked in the league for over a decade. I'd hate to see him setup to fail.
I don't really want to see another Trammell type situation... in that a home town hero gets fired. It seems like he is the type of personality that could skip the whole assistant coach thing. JD could certainly be frank with him. I guess what it comes down to is that I want to see a coach who likes hard basketball and who'll expect intensity from the players. If we can find someone else like that, then just as well. How about Charles Oakley?
Thats been the general trend. Irvine to Carlisle, Brown to Flip. Except for Carlisle to Brown and Gentry to Irvine. Of course before that Collins coached between 2 softies.
I read an interview with one of the Shock players a few years ago where she talked about Laimbeer's coaching style. Apparently he is a hard ass who pushes the players to be better. He also forced them to watch alot of game tape to see where their strengths and weaknesses lie. I'm all for giving Laimbs a chance. It worked out pretty well for Avery Johnson. I would also suggest that part of his coaching staff include: Lindsey Hunter: Defensive Specialist Rick Mahorn: Chief Motivator and Effort coach (I know. I'm a total homer)
Daly used to say that Laimbeer really understood the mental approach to the game. I'm willing to give it a try. There's no question he'll get respect from the players. What are the other options? If JVG comes available he'd be a good one, though I don't understand why he's been less successful in Houston.
laimbeer owned the mental approach to the game as a player. one thing's for sure...he'd take some of the heat off sheed!! haha. he's entertaining to watch on the sidelines coaching the shock
Honestly, I think Laimbeer gets too much credit sometimes. The true genius behind the Bad Boys was Chuck Daly. You could say (and The Low would emphatically agree) that the genius behind our title run was Larry Brown. It is very hard to win a title (let alone make the Finals) without an elite coach. The only recent slightly above average coaches I can think of are Larry Bird and Byron Scott. And they were both losers. Larry Brown, Pat Riley, Gregg Popovich, Phil Jackson, Chuck Daly and Rudy Tomjanovich have won the last 20 titles. They have also lost 6 Finals during that time. So in 40 possible appearances over that span, this elite group has been in the Finals 26 times.
That stat alone is very telling. The next coach to join that elite 6 will really have something to be proud of. Does anyone really see Flip joining that band of coaches...ever?
You could also say that Darko Milicic, Shaq, Tim Duncan, Michael Jordan, Hakeem Olajowon, and Isiah Thomas won the last 20 titles.
Not really the same. Milicic had no impact on the title except for the Human Victory Cigar t-shirts.
OK, maybe replace Darko with Ben on my list. My point is that if you choose between the following for your team, who would you choose (assume that the players are in their prime). Michael Jordan or Phil Jackson Ben Wallace or Larry Brown etc. Clearly, the franchise players are more important. Since almost all teams that are poised to win a Championship try to get an elite coach, it may be more correlation than cause-effect. Do you not think that there were any other coaches out there besides Phil Jackson that couldn't have won a Championship with MJ? In the same way, an elite horse will get a great jockey. It is the icing on the cake, not the reason the horse ended up winning.
Actually I don't. The league has been filled with elite teams who have not been able to put it together to win the big one. The Lakers couldn't get pass Utah without Phil Jackson. The Bulls did not become a great "team" until Phil took over. Jordan's ability and intelligence made Jordan the greatest player of all-time, but Phil helped Jordan to become a champion. You are correct that a coach needs a good team in order to win a championship (see Larry Brown's struggles). But take a look at it from this perspective... when the supposedly two best teams in the league meet at the end of the NBA campaign, the high profile coach historically takes home the trophy. And I wish you were right about the contender seeking a high profile coach thing because if you were, we wouldn't have landed Flip.
It could also be argued that those teams gained the necessary experience through their failures to eventually win. Also, some of those situations took an aging dynasty to fall apart before the team that was knocking on the door could emerge. The Bad Boys could have won earlier if the Lakers weren't peaking. The Bulls similarly relied on the deterioration of Detroit's bench to edge us out. It is doubtful that the Rockets would have won 2 Championships in the 90's if Jordan hadn't retired (would that still make Tomjanovich an elite coach?). Is Jerry Sloan not an elite coach? And didn't he have some amazing talent? They both matter, but I think that the best way to determine the relative importance of coach's is to look at their salaries. Another confusing factor is that a team will rarely fire a coach after a Championship. This fact makes is difficult to see if those teams would have also won with another coach... say a Flip. And I'm in no way trying to argue that Flip is capable of winning anything.
Jerry Sloan. That is who we need.
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Round 1 Mini-golf
Trip Start Aug 09, 2008
6Trip End Aug 14, 2008
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The sun was hot today. The humidit was higher and there were fewer clouds overall today. But we found a better chair farther away from the annoying speakers and kiddie pool. Plus with the shure headphones in my ears, I was able to relax. Unfortunately, I chose to finish my book instead of napping. Hopefully I will sleep some more tonight and or tomorrow. Those Olympics are too addicting.


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At editor's home editor's wife and Chandra were preparing to cook, Vignesh asked permission to get in and he was in chef costume. He told that cooking was his hobby and today he was going to cook. He added some spices to potato and fried it. Everyone was surprised when they taste that. Editor's wife congratulated Chandra that she was so lucky to get a husband like Vignesh. Vignesh send everyone out from kitchen except Jansi, to the help of Jansi Vignesh cooked something. He just managed that he was a good cook.
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A nonprofit institute where scientists, educators, and entrepreneurs translate the power of genomics into real world results to create a healthier more sustainable world.
Our Faculty
Ph.D. in Biochemistry, University of California Berkeley
Genomic and genetic analysis of human traits and diseases.
Richard Myers, PhD, is president and scientific director at HudsonAlpha. Myer's lab focuses on applying functional genomics and genetics approaches to understanding how genes and regulatory regions contribute to basic biology, human disease, responses to the environment and population genetics.
PhD in Pharmacology, University of Iowa
Genomics, common human disease
Howard Jacob, PhD, uses molecular genetics to understand complex, multifactorial disease. As executive vice president for genomic medicine at HudsonAlpha, Jacob brings together genome sequencing, bioinformatics and basic research to make a clinical diagnosis possible for patients.
MD, George Washington University School of Medicine
Human clinical genetics
David Bick, MD, PhD, is a clinical geneticist with more than 20 years experience diagnosing and treating children with genetic disorders. Bick is the medical director of the Clinic for Genomic Medicine on the HudsonAlpha campus.
Ph.D. in Biochemistry and Molecular Biology, Emory University
Epigenomic analysis of complex human traits and diseases
Devin Absher, PhD, uses the epigenome to study complex diseases and traits, especially autoimmune disease, cardiovascular disease, cancer and aging.
PhD in Genetics, Imperial College, London, UK
Clinical and translational use of genomic data
Liz Worthey, PhD, uses genomics and informatics to define the genetic underpinnings of human disease. In addition to her research goals, as the director of software development and informatics, she leads her team in supporting the informatics goals of the institute as well as the clinical mission to provide definitive diagnoses for patients.
M.D. and Ph.D. in pathology, University of Washington, Seattle
Genetic architecture of morphologic variation
Greg Barsh, PhD, MD, studies the genetic mechanisms that underlie differences in individual appearance and that could give new insight into both basic biology and human disease.
Ph.D. in Genetics, Stanford University
Human Genetics and Genomics
Greg Cooper, PhD, researches the structures, functions and evolutionary histories of human genomes, with an emphasis on applying genomic approaches to study human disease.
Ph.D. in Microbiology, University of Leeds, United Kingdom
Genomic resource development for plants
Jane Grimwood, PhD, co-directs the Genome Sequencing Center at HudsonAlpha, managing one of the few centers in the world that produces, analyzes and interprets genomic data on economically important plant and organism species to improve crop breeding and other agricultural practices.
B.S. in computer science, B.S. in biology, North Central College
Whole genome sequencing and assembly, population genomics
Jeremy Schmutz co-directs the Genome Sequencing Center at HudsonAlpha, managing one of the few centers in the world that produces, analyzes and interprets genomic data on economically important plant and organism species to improve crop breeding and other agricultural practices.
M.D., SuZhou Medical College, China; Ph.D. University of Alabama at Birmingham
Technology development to advance medical science
Jian Han, MD, PhD, focuses on developing integrated solutions for molecular differential diagnosis and mapping the personalized immunorepertoire.
MD, Comenius University, Martin, Czechoslovakia
PhD in Physiology, Comenius University, Bratislava, Czechoslovakia
Genomics, Common Human Diseases
The ultimate goal for personalized genomic medicine is tailoring treatment. Because we expect the majority of patients to have a unique sequence variant, tailoring treatment for patients with rare disease will require validation nominated sequence variants using different molecular biology approaches. In the validation process, the Lazar lab will utilize primary patients or commercially available human cell lines for different cellular assays or vertebrate model system using gene editing to generate and functionally test the variant of interest. The goal of Lazar's work is to develop a functional screening program to rapidly test variants or genes identified in individual clinical cases and testing potential treatment modalities
PhD in Biology, Dartmouth College
Understanding the role of the rhizome in resource reallocation and perenniality.
Kankshita Swaminathan, PhD, studies the role of the rhizome in nutrient storage and reproduction in plants. She is interested in how perennial plants remobilize nutrients year after year.
PhD in Bioethics, University of Sydney, Sydney, NSW Australia
Genomics and Ethics
Kim Strong, PhD, is a genetics-trained bioethicist, a scientist who studies the application and limits of empirical ethics, particularly as it relates to contentious and emerging genetic technologies.
Ph.D. in Genetics and Molecular Biology, Emory University
Educational outreach relating to genetics, genomics and biotechnology
Neil Lamb, PhD, oversees all educational programming developed at HudsonAlpha as vice president for educational outreach. Lamb creates innovative teacher training, student experiences, public enrichment, classroom kits and digital resources that re-shape how science education is delivered.
Ph.D. in Genetics, Stanford University
Sara Cooper, PhD, focuses on combining metabolomics with genomics and applying that data to pancreatic and ovarian cancer.
Ph.D. in Biochemistry, Emory University
Technology development and automation, informatics, genomic variation
Shawn Levy, PhD, uses high performance genotyping and sequencing technologies to support projects from plant and animal phylogenetic studies to translational and clinical based projects at the Genomic Services Laboratory and the Clinical Services Laboratory.
PhD in Cell Biology, University of British Columbia, Canada
Molecular mechanisms of sarcomagenesis.
Le Su, PhD, has been actively involved in sarcoma research for nearly ten years. As a junior fellow at HudsonAlpha, his major focus is on chromosomal translocation-associated sarcomagenesis in children and young adults.
Our Genomic Research
Since opening its doors in 2008, HudsonAlpha has further secured its role as a global leader in biotechnology and genomic research. We've made discoveries in ALS, childhood genetic disorders and kidney cancer; expanded research in bipolar and schizophrenia and continued critical research in other devastating conditions, including cancer, Parkinson's, lupus, multiple sclerosis and more.