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Patient Education Report: Patients on Call
Patient Education Report: Patients on Call
They're becoming the new key opinion leaders. Savvy, influential patients have pharma's attention and are growing relationships with industry, online and off. Marc Iskowitz on how firms have just begun to tap the potential of this emerging segment
While many pharma and device firms remain on the sidelines, understandably so, the lure of gaining a rapport with patients on social networks is reason enough for some to venture forth, despite the unknowns. Roche Diagnostics is one example. About four years ago, the Indianapolis maker of blood-glucose meters, insulin pumps and other diabetes-testing gear decided to jump into the digital sphere, but in a brick-and-mortar kind of way.
"The Accu-Chek brand was really early to the game, which has helped us tremendously," says Robert Müller, associate marketing manager of diabetes care for the firm. "Instead of dithering on whether we should or not, and how do we, we had some visionary people who thought, 'We really need to interface with the key opinion leaders,' who at the time were online diabetes bloggers."
And thus was born the Roche Diabetes Social Media Summit. The purpose in holding court with bloggers, explains Müller, was "to try and figure out a way to get involved that is helpful to people with diabetes, without offending them."
It invited the 30 most influential diabetes writers in North America—people like Kerri Sparling and Manny Hernandez—to its headquarters "just to meet with them and talk about how we work together." Today Roche is a sponsor of Sparling's blog and supports some of the online programming created by Hernandez's foundation.
Two years after the debut of its social media summit, Roche took another step, launching a Facebook page (facebook.com/AccuChekUS) and Twitter account (twitter.com/accuchek_us), as well as expanding its own blog (accu-chekdiabeteslink.com), launched in 2009, to cover both Canada and the US. It also started to maintain a presence on third-party sites tudiabetes.org, diabetesdaily.com and childrenwithdiabetes.com.
Roche says it uses the channels to listen to its audience and to promote diabetes education, awareness and advocacy. Patient conversations range from the cost of insulin to product reviews. Since 2009 the diabetes online community has swelled, and Roche is bent on tapping it for insight.
Like a physician KOL
"I don't think you can hope to serve your audience without knowing them," Müller tells MM&M. "The people who do that best—who truly understand the needs of their audience—are going to win. They're going to be the strongest companies."
Over the past year or so, the role of patients as an influence and information channel for pharma has blossomed. Experts on the trend say it's comparable to the rise of key opinion leaders (KOLs) in the physician world—doctors, typically from academic medicine, who reach out to other physicians likely to prescribe a product.
Two main groups of patient advocates have experience with products. The first receives training from boutique agencies like HealthTalker and Snow Companies, which specialize in word-of-mouth communications and use the real-life stories of patients to deliver marketing messages.
The second and perhaps most visible segment of patient advocates are those, like Hernandez and Sparling in the diabetes realm or Dave deBronkart (aka e-Patient Dave) in cancer, who are especially adept at creating content. The foremost bloggers have become, effectively, small communications firms unto themselves, says Jack Barrette, founder and CEO of Wego Health, an online patient network that also acts as a liaison between its "health activists" and pharma to create educational programs.
"[The high-profile advocates and bloggers] want to communicate very valuable content and have created an agency structure—they're professionals, in a good way, and have managed to carve out areas where they can be seen as agency-like," Barrette says.
Beyond that top layer is a group who also blog but don't necessarily support themselves through their advocacy. It's that group, which Barrette calls the health activist middle class, that companies are now learning from: "They're so powerful because their numbers are so vast, and they're trusted because they're not semi-professionals."
There's a third tier online, "who don't even consider themselves patients," observes Wendy Blackburn, EVP, Intouch Solutions. Around a third of US adults use social media as a health resource, according to a 2012 survey of 1,060 US adults by PricewaterhouseCoopers, and most probably fall into this third group.
"It's someone who maybe just got diagnosed and doesn't even realize there's this discussion we're having about pharma and social media," says Blackburn. "They just go online for information."
A stake in the ground
Belgian drugmaker UCB seems to target more of that rank-and-file set. UCB—whose brand portfolio spans Parkinson's disease patch Neupro, seizure therapy Vimpat, and Cimzia, a biologic for rheumatoid arthritis and Crohn's disease—started engaging patients online as another way to provide value. "We want to put a stake in the ground, to be an active part of the community," says Chemelle Evans, UCB associate product director, CNS.
The firm sponsors microsites, like the recently launched EverydayRAvictories, where patients can post stories; Facebook pages, such as facebook.com/parkinsonsmorethanmotion; as well as YouTube channels, like YouTube.com/epilepsyadvocate. These efforts dovetail with consumer-facing commitments like educational magazines, scholarships, involvement with non-profits, and marketing campaigns.
The drugmaker mines user-generated content for insights. "It's one thing to do traditional market research and get, at a point in time, what someone is thinking," explains Patricia Choumitsky, senior manager, immunology for UCB. "It's something very different to listen to them in an interactive way. By seeing their responses to everything you do, you can quickly and dynamically shift your focus." One example was what she calls an "online social private research community," the firm hosted with arthritis patients. "As a result of the community, we changed one of our direct-response offerings to something that better met the patient need," says Choumitsky. The offering is MY RA Fit Kit, a free exercise program.
The pitfalls of participation
Participation is not without its pitfalls. For instance, sources say patient-generated content is vulnerable to the same creative restrictions as most healthcare marketing.
"The FDA views patient ambassadors as testimonials," says Brenda Snow, the founder and CEO of Snow Companies, "and if a patient says anything about a brand…the FDA views that as an extension of that company, so all the promotional, legal and regulatory [stipulations] have to be upheld."
With patient blogs and testimonials thusly constrained, that could mean the public will become as jaded toward them as they have become toward drug commercials on TV.
Marketers playing in social media also need to stay vigilant and ride the waves of the shifting digital landscape, such as when Facebook abruptly changed course in 2011 and forced pharma pages to open their walls to user comments, prompting several drugmakers to shutter theirs rather than commit to 24/7 monitoring of posts.
So far, that hasn't scared Roche Diagnostics. About a year ago, it started using its Twitter channel for customer support, and its care staff monitors around the clock. A member of the staff will jump into a discussion when there's a need to point those who are diagnosed toward credible online resources.
"If pharma can drive patients to accurate information, it furthers the goal of optimizing treatment experience and promoting adherence," says Tara Rice, manager of health education for the agency HealthEd. Rice points to a 2012 Wolters Kluwer survey that found 65% of people who turn to the internet with medical questions say they trust the information they find, "which is scary, because there's a lot of inaccurate information online."
ROI evidence is also scant. Roche's Müller declines to quantify it, preferring instead to focus on soft indicators that responding to users on these platforms moves the trust meter. "The fruit of that is in a user pointing out during a conversation in a forum, 'I know the guy from Accu-Chek is here,' and I'm brought into the conversation. That shows rapport, that you're doing something right."
Asked for metrics, UCB's Evans points to the firm's epilepsy Facebook page, facebook.com/epilepsyadvocate, which has over 43,000 fans. She notes that some newly launched properties are steadily growing and increasing their fan base daily, but adds that it still "takes courage to get engaged in these emerging-media platforms."
Daring though they may seem relative to industry peers, these companies say they haven't sacrificed compliance for the chance to get closer to their key audience. Still, marketers say, doing so is more art than science.
The FDA has yet to issue an official guide book to social media. A little more than a year ago, it issued draft guidance on "Responding to Unsolicited Requests for Off-Label Information About Prescription Drugs and Medical Devices," which some interpreted as a sneak peek. But the agency has yet to clarify the situation.
Nevertheless, patient advocates and some pharma and device companies seem to be finding ways to work together.
"At the end of the day, it's been a very rewarding experience to be able to engage [patients] in this way, and as an organization committed to making a difference in patents' lives, we have to be willing to take that step," urges Evans. "Weigh the pros and cons, like anything, but don't shut the door on this amazing opportunity to help make a difference for patients' lives."
Next page: Three Patient Ambassadors give the patient perspective on pharma.


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Although I have an amount of ammo for it, I don't currently possess a rifle that uses 30-06 ammo. I have thought about maybe buying a cheaper model of Savage, Ruger, Marlin or possibly a couple of others. I think any one would be sufficient.
But, I am also thinking of another approach. I have a single shot H&R/NEF rifle in 45-70 caliber. It is fun to shoot. I like this gun really well. I don't need the 45-70 caliber, but, I have it and plan to keep it. I have some ammo for it, too. And, when I visit local gun stores they seem to be able to obtain a few boxes of that ammo. So, It's a keeper.
However, H&R has a program where you can send in the action of any of their single shot rifles that you have, and they will fit it with barrels of other calibers. So, I am thinking of doing this. They charge $96 for a 30-06 barrel. There are also a charges for fitting the barrel and shipping the gun back. I don't know what these charges are. But, it would probably be an economical way to obtain a 30-06. For me a single shot would work. I would not plan to use it for defensive purposes.
H&R also offers a 50 caliber black powder barrel for this action. The cost is somewhere around $115, I think. I believe that having a black powder rifle would be good, especially in a survival situation. So, I am considering doing that. It would make me have ONE rifle in 3 calibers-one being black powder. I don't think that it would cost much more than $300 for everything-two barrels, fitting and shipping.
I really want to do this.

subset: commoncrawl


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In Cancún, Party is Synonymous with Paradise
Grand Park Royal Cancún Caribe • Cancun, Mexico
Escape Kit
- A Four- ($959), Five- ($1,199), or Six-Night ($1,438) Stay for Two in a Deluxe Ocean View Room from January 3 until March 30, 2013
- Or, a Four-($799), Five- ($999), or Six-Night ($1,199) Stay for Two in a Deluxe Ocean View Room from April 1, 2013 until December 20, 2013
- One Bottle of Wine and Chocolates Upon Arrival
- All-Inclusive Of:
- Unlimited Meals at Four Restaurants
- Unlimited Drinks (Alcoholic and Non-Alcoholic) at Four Lounges
- Never-Ending In-Room Mini Bar and All-Day Snacks in Three Refreshment Stands
- Use of Non-Motorized Water Sports
- 50% Off Spa Services
- Nightly Entertainment
- Taxes and Gratuities
- Combine Unlimited Vouchers to Extend Stay
Judging from the pulverized pillars of Las Ruinas Del Rey and the fallen walls of Yamil Lu'um, party seekers have been bringing down the house in Quintana Roo long before its state-aided tourist boom in the 1970s. You'll have no trouble razing the roof at Grand Park Royal Cancún Caribe, where 400 meters of coastline, poolside, and rooftop bars faithfully perpetuate the Yucatán Peninsula's propensity for throwing down.
"Like Las Vegas, Ibiza, or Dubai, Cancún is a party city that just won't give up. Top that off with a pretty damned good beach and you have one of the western hemisphere's biggest tourist draws, bringing in as many as four million visitors (mostly from the US) annually," says Lonely Planet.
Tear yourself away from the never-ending in-room mini bar and you'll see your Deluxe Ocean View Room is true to its name—turquoise tides slide ashore sugar-soft sands just paces from your balcony or terrace. The property proffers two pools: One's rocking with volleyball and dancing and the other's for knocking out Zs on bali beds. Be it boogie board or pedal boat, kayak or sailing skiff, Caribbean floatation is on your horizon with the use of all non-motorized water sports included. And variety is on the menu with unlimited dining at four restaurants.
Climbing Coba, the Mayans' highest pyramid, is a feat worth accomplishing, but feeding fruit to the Iguanas at the top makes it a fait accompli. Mexico's most-visited venue Chichen Itza, meanwhile, joined the New Seven Wonders club in 2007. Underground rivers and natural wells—"cenotes" to geologists—are best accessed at Xcaret, an archaeological park on the Riviera Maya. Their tropical jungle trails and butterfly pavilions lend a lavish lushness to your already plush vacation.
For semi-precious stones and semi-clad dancers, Ciudad Cancun (the city proper) is the place to go. Jewelers set onyx in the marketplace by day and sweaty bods bump in the night at Coco Bongo. The outskirts are flush with flamenco-dress flowers and low-forest trees, which the Keel-billed Toucans just love. As you visit the coral reefs, mangroves, and bird sanctuaries, it becomes clear that every creature was invited to this peninsular party.
"Cannot speak highly enough of the resort, staff, and all of the inclusions. Great location for proximity to shops, markets, and night life. The entertainment staff makes the resort even more enjoyable."-- TripAdvisor
escapes 30-day promise
LivingSocial gives you up to 30 days to return your unused voucher for a full refund. Once you've made a reservation, you are subject to the merchant's cancellation and refund policy. If you want to secure your preferred dates of travel, we strongly recommend that you complete reservation with the merchant within 30 days of your purchase—after that, LivingSocial will not issue any refunds.
the fine print
- Vouchers may be combined to extend stay
- Reservations required and subject to availability
- Not valid on group or existing reservations
- Cancellation/re-scheduling policy of applies; voucher subject to forfeiture
- Two children ages 6 and under stay and eat free, ages 7 to 12 are $53 per night per child
- Call the property for pricing related to adding any other guests
- Voucher is all-inclusive of unlimited meals at four restaurants, unlimited drinks (alcoholic and non-alcoholic) at four lounges, never-ending in-room mini bar, all-day snacks in three refreshment stands, use or non-motorized water sports, nightly entertainment, taxes and gratuities
- Voucher includes one bottle of wine, chocolate covered strawberries and 50% off at the spa
- Nights must be used consecutively
- All deal components must be redeemed during one stay
- The deal is valid only for date range purchased and may not be exchanged or redeemed for any other dates
- Other conditions apply • PAID AND PROMOTIONAL VALUES EXPIRES ON December 20, 2013 • PAID VALUE DOES NOT EXPIRE • PAID VALUE EXPIRES ON December 20, 2018 • PROMOTIONAL VALUE EXPIRES ON December 20, 2013 • Enjoy By December 20, 2013
Other conditions apply
Except where noted in the fine print:
• Cannot be combined with any other offer or promotion
• Tax and gratuity are not included
• Merchant is responsible for the quality of the products or services provided to you at redemption
• LivingSocial Terms and Conditions - https://www.livingsocial.com/terms
Original Price:
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Mobile Advertising: Will this be the Premium Advertising Platform?
Jan 10, 2012
Advertisers often lump smartphones and tablets into the "mobile" category, but I think we need to focus less on their portability, and more on how these devices are used. A smartphone is constantly connected and is mostly used on the go, whereas a personal computer tends to be more stationary. Plus, people have grown accustomed to the type of ads they see on both of these devices.
A tablet, however, falls somewhere between the smartphone and the traditional web experience one has on a computer. We are still at the very early stages of understanding how consumers are using this device – only 10% of consumers own one, compared to the 44% who own smartphones and nearly 80% who own personal computers. But, Forrester Research projects that U.S. tablet sales will grow from 26 million in 2011 to more than 50 million in 2012.
So what is the right format for this advertising? Is this experience a lean-back and watch interface, or do people expect to engage with ads like never before? Are in app-ads the best way to go? Is it video?
If we look at how consumers use their tablet devices, we know that its main uses are gaming, web browsing and email, with ecommerce quickly gaining an edge. In fact, a recent study conducted by comScore and Jumptap found that 63 percent of tablet owners have made a purchase with their device.
This tells us that their experience is not unlike the traditional web browsing we've seen for years. Our research shows that tablet usage occurs mostly in the morning and evening (50% above day usage), which clearly suggests that PCs are being replaced by tablets. Additionally, tablet users sessions are significantly longer - almost 5X longer - than mobile devices, also suggesting that tablet usage is PC-like.
But what makes a tablet different is the functionality of the device. The touch screen on a tablet is very different from that which ones uses on a smartphone, and is completely different than most PCs. This needs to be the driver of advertising innovation on the tablet.
People aren't looking for a traditional 250x300, click-induced direct response ad – they want to be able to swipe and drag through ads as if they were apps themselves. We need to push ourselves to build not only the technology for a dynamic content experience on tablets, but an incredible ad experience as well.
If you're at CES today, stop by Digital Hollywood at CES at 12 pm PT to discuss this very topic.
Track I - STC7 - SmartPhone & Tablet Conference
Location: North Hall N261
iPad-Tablet-SmartPhone Advertising - the Premium Advertising Platform
Mobile Advertising: Will this be the Premium Advertising Platform? aol.it/yAAMip #CES #mobile
- AOLPR (@AOLPR) January 10, 2012


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|GTA V Latest News | #GTAV | #GTAOnline
2013 Official GTA V website gets updated
Grand Theft Auto V - General News | @ 09:57 AM MDT | By rappo
Today Rockstar Games has updated the official GTA V website with some content set up as a travelogue intending to entice us to want to visit Los Santos and Blaine County. It's working...
The update includes many new screenshots and further details on game features like vehicle customization, shopping, air travel, aquatic adventure, outdoor activities, and gang wars with MUCH more coming soon!
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In the building-design and construction industry, "green" strategies and techniques commonly are believed to add significant cost to budgets. In fact, a Building Design+Construction magazine survey1 puts the percentage of architecture, engineering, and construction firms believing green building costs more than traditional methods of design and construction at 85, with 41 percent of those firms believing green building costs at least 11 percent more (Figure 1). A Davis Langdon ...
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Investor Rights or Citizens Rights
The Dangerous Expansion of NAFTA Investor Protections Through the FTAA and WTO
Many people would be surprised to learn that their government has, in many ways, given up its sovereign right to pass laws protecting citizens' health, the environment, and labor rights. They would likely be more surprised to find out that the wheels are in motion to enact trade agreements that further threaten democracy by granting additional rights to giant multinational corporations (MNCs). This, however, is the frightening reality underlying trade agreements that are currently being negotiated. If multinational corporations succeed, new investment agreements under the World Trade Organization (WTO) and the proposed Free Trade Area of the Americas (FTAA) will ensure that democracy is further eroded in exchange for corporate profit maximization.
It is not surprising, however, that the average citizen is not aware that the current situation is unfolding. This is no accident. The negotiations are undemocratic, they lack transparency, and they are being conducted without input from the very citizens whose lives will be affected. It is ultimately in the interest of MNCs to hasten the progress of such negotiations without interference from civil society, as such propositions would likely be met with strong resistance in the face of a public dialogue.
The Growth of Foreign Investments
Foreign direct investment (FDI) is one of the most politically sensitive 'trade' issues, as it involves foreigners exercising control over national assets and resources through investment. When a company closes a factory in the U.S. and moves it to China to take advantage of cheap labor, it is investing in China. The expansion of this FDI in the global economy has reached an unprecedented level. In 2001 more than 65,000 transnational corporations had expanded FDI through the creation of more than 850,000 foreign affiliates. That companies invest in foreign production is good, as long as they do it in ways that respect local laws and benefit local development. Not unexpectedly, MNCs have been actively lobbying governments to ensure that agreements are included under both the FTAA and WTO to strengthen the rights of investors at the expense of the rights of citizens.
Investment agreements currently proposed under the WTO and FTAA will greatly restrict the ability of governments to implement national policies for development and poverty reduction - the same policies that were used by the industrialized countries to develop. Furthermore, such agreements conflict with the 1962 UN Resolution on Permanent Sovereignty over National Resources, whose mandate is to regulate foreign investment by recognizing the state's permanent sovereignty over natural wealth and resources as a key component to the right of self-determination.
Investment Agreements: Following in the Footsteps of NAFTA
Investment agreements under the FTAA have been drafted to model the North American Free Trade Agreement (NAFTA). WTO negotiators from rich countries, including the U.S. and the European Union, are pursuing investment protections under the WTO according to a similar model. Much like NAFTA, an agreement of this type will be designed to maximize the rights of foreign investors while minimizing the authority and rights of governments to pursue policies crucial to their national interest.
The rich countries are pushing to include a package of "New Issues" that are not currently in the WTO, that include investment, government procurement, competition policy, and trade facilitation. If successful, these New Issues will spell the end of the role of government in setting any policies to regulate foreign capital within the national boundaries. If this becomes a reality, the scope of protected capital will be expanded to include portfolio investments, short-term capital flows, and real estate.
Preventing Opportunities for Development
Proponents of establishing investor protections under the WTO are pushing for binding rules that would allow foreign investors to enter countries without conditions or regulations, and to be granted "national treatment". If granted national treatment, foreign investors must be treated no differently than domestic investors. If such agreements become a reality, developing countries will be prevented from taking the very same actions that developed countries took in their early stages of industrialization. Specifically, they will be prohibited from providing tax incentives, targeted subsidies, and purchasing contracts to developing industries so that they can compete against foreign firms. Because of the natural advantages the MNCs have as large experienced firms, the predictable result of such disastrous policies will be unfair preferences for foreign investors.
Outlawing Performance Requirements
Performance requirements, crucial for meeting development goals, will also be prohibited if such agreements are established. Developing countries will lose the ability to demand use of local materials, local labor, and demand technology transfer, which stimulate growth in the local economy. Additionally, the improvement of environmental and labor standards will be nearly impossible as countries will be pressured to compete in a "race to the bottom". This will particularly prove true if, as under NAFTA, governments are prohibited from screening investors on the basis of such criteria as worker compensation or environmental standards.
Investor Rights Over Citizen Rights
Perhaps most alarming are the provisions that would model those in NAFTA's Chapter 11. Under NAFTA's Chapter 11, governments are prohibited from passing laws which adversely affect the business of foreign investors, regardless of the role that such legislation would have in meeting national social and development goals. In the event that such legislation negatively affects the profits of a multinational corporation, individual companies have the right to sue the foreign government in a secret NAFTA tribunal - bypassing the national courts. If the corporation wins, the accused government must then compensate the corporation in the amount of profits they claim to have lost - including hypothetical profits that they claim they would have made twenty years into the future! This confers new rights on MNCs that neither domestic companies nor citizens - who have to obey national laws - enjoy. It creates a class of "supercitizenship" for foreign corporations at the expense of citizen sovereignty.
Multinational Corporations in Action
In 1999, Methanex, a Canadian corporation that produces the gasoline additive, methanol, sued the U.S. government for $970 million. The lawsuit arose following a California ban on the substance after studies confirmed that it was leaking into the ground water, causing cancer in the population. Under NAFTA's Chapter 11, Methanex Corporation claimed that California's ban constituted a "confiscation" of its property and was "tantamount to expropriation" - a violation of Methanex's rights as investors. The case was brought in front of a NAFTA tribunal whose proceedings are closed to the public. As of July 2003, the case was still pending. If Methanex prevails, American taxpayers will be forced to pay the corporation $970 million for the right of California lawmakers to protect the very health of its citizens - or change the law. Such a ruling will have a chilling effect of deterring lawmakers from enacting future laws to protect the public if they conflict with the interests of large corporations. There are 14 such cases under NAFTA, and each case so far has been decided in favor of the corporation.
Wheels in Motion: Moving Towards Multilateral Investment Agreements
In spite of promises made by developed countries to focus the agenda at the WTO Cancun ministerial on development issues, rich countries instead lobbied heavily to expand the WTO by adding a new agreement on investment. The effects of developing such an investment agreement would be disastrous for the welfare of people and the environment in both developed and developing countries, as legislators will lose the sovereign right to pursue policies that puts the public interest above corporate interests.
Resisting Corporate Domination
Many developing countries expressed their opposition to bringing new investment issues to the Cancun ministerial of the WTO in September 2003. It was clear during the negotiations that rich countries employed strong-arm tactics to attempt to force the introduction of the investment issue despite clear opposition. However, on the last day of the ministerial, large groups of developing countries came together and voiced their total opposition to the launching of new negotiations on investment and other New Issues. This strong coalition of diverse developing countries maintained solidarity to oppose the rich countries' agenda, and scored a clear victory for democracy and the poor in Cancun. It is imperative that developing countries continue to oppose the launching of investment negotiations in the WTO, and that citizens continue to hold their representatives accountable.
Alternative Proposals
Developing countries must retain the autonomy to pursue strategies that ensure that foreign investment contributes in a positive manner to the realization of national goals. Additionally, developed countries should pursue trade positions that will benefit the public welfare rather than the bottom line of a few large multinational corporations. To this end, binding obligations on investors should be instituted to ensure that they behave in a manner that is consistent with international human rights and development objectives. A fair and equitable trade agreement would include measures to counter corporate predatory business practices, anti-labor policies, and environmental degradation. Finally, in order to make corporations more accountable, enforceable international standards should be established for the reporting and disclosure of information.
Eight years of experience with the WTO has shown that it is still dominated by the interests of rich countries and elite businesses around the world. It's time for a fundamental review of the WTO's impact, and to scale down or abolish and replace the WTO with a completely different institution. Furthermore, an alternative to the FTAA draft currently being negotiated must be developed so that issues of social justice are not subordinated to corporate interests. Strengthening the rights of investors will do little to benefit working people in either developing or rich countries. On the contrary, an agreement of this nature will benefit corporate interests at the expense of ordinary citizens.


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Act Tonight to Stop a Destructive Deficit Deal
Posted by Kirsten Moller in Featured, Stop Funding War, World News & Events on 1st August, 2011 | No Comments
After weeks of wearied debate, hand-wringing and general confusion over the debt ceiling, a deal has finally been announced by President Obama and legislative leaders, and the "no-new-taxes/shrink-government" folks have won. While the wealthy and corporations benefit from this deal, the people risk losing what remains of our most important safety benefits that we have worked so hard to secure and what tens of thousands who have been disadvantaged from corporate greed and bad policy rely on. We must take the stand our President can't or won't take – Tell your representative to vote NO!
Read More...


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Patriots down Nevis boys 77-56
The Pequot Lakes boys' basketball team snapped a four-game losing streak with a 74-56 win over the Nevis Tigers on Friday, Feb. 22.
The Patriots' Jordan Redmond scored 24 points while John Craig had a season-high 13 points in the non-conference win.
Pequot Lakes, 10-14 overall, played at Esko on Tuesday, Feb. 29, before hosting Sebeka in the final regular season game at 7:15 p.m. on Friday, March 1.
The only time the Patriots trailed was 7-6 early in the game. That's when baskets by Redmond and Kevin Beltz put Pequot Lakes ahead for good. The Patriots led 10-9 before scoring eight straight points, including four by Travis Jacobson and four by Wes Mumm.
Nevis answered with a pair of free throws, but Pequot Lakes went on a 10-0 run, and eventually led 44-25 at the half. Early in the second half, the Patriots built a lead of 23 points and the game was never threatened.
"It was a nice win tonight as we got some nice play from our guards," said Pequot Lakes coach Garry Grewe. "Our two big guys (Redmond and Jacobson) did a great job in the paint."
Almost half of the Tigers' points came from the free-throw line as they made 25 of 34 attempts.
Nevis was led in scoring by Gavin Becker with 23 points while Jacobson added 12 for the Patriots, who hosted Parents' Night.
Nevis 25 31 — 56
Pequot Lakes 44 30 — 74
Griffin Chase 4, Courtland Chase 2, Gavin Becker 23, Jordan Dudley 2, Taylor Chase 6, Jordan Feder 2, Jacob Keranen 17. FT 25-34 (74 percent).
Brett Peterson 2, Kevin Beltz 4, Jack Kreitz 2, John Craig 13, Wes Mumm 8, Michael Ryan 4, Jordan Redmond 24, Tyler Tappe 5, Travis Jacobson 12. FT 7-13 (54 percent).
Perham 61, Patriots 33
Pequot Lakes had its lowest point total of the season in a loss to the host Perham Yellowjackets in non-conference play on Tuesday, Feb. 19.
Perham jumped out to a 31-12 lead by halftime, and cruised past the visitors. Only five players scored for Pequot Lakes, led by Jacobson with 12 points and Redmond 10.
Perham 31 30 — 61
Pequot Lakes 12 21 — 33
Eli Beachy 13, Hunter Salathe 6, Tyler Glines 9, Nick Bahls 2, Jacob Anderson 15, Matt Formanek 4, Christian Weis 2, Jordan Hein 4, Josh Nordick 2, Sam Muer 4. FT 2-4 (50 percent).
Brett Peterson 3, John Craig 3, Jordan Redmond 10, Tyler Tappe 5, Travis Jacobson 12. FT 2-7 (29 percent).


text: Using the assets it acquired in the purchase of Questron Technology, Inc. and its subsidiaries, GE Supply, Shelton, Conn., recently launched GE Supply Logistics, LLC. The new Dallas-based business unit will develop and distribute supply chain management and inventory logistics management programs through two operating units, GE Supply Logistics and GE Supply Aerospace Logistics. According to Jason


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The outflow of Yellow Belly Creek from Yellow Belly Lake, Sawtooth Mountain
Lakes and streams are often linked together and it is important to understand the ecological interactions between the two. Lakes trap fine sediments, warm the water, and buffer the transport of nutrients, thus making outflow streams more productive. Photo by Linda L'Ai 2003.
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A small town outside of Quito, Ecuador, where many painters and artists live. It has beautiful landscapes and very friendly people.
I used to live in Alangasí. It is a rather peaceful place. Great place to live if you like reading poetry and relaxing.
by Raúl Soleimani January 23, 2009


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[Article]-Video: eLS Launches Hack.me Free Virtual Labs for Web Application Security
So get learning, get sharing and get hacking!!
Permanent link: [Article]-Video: eLS Launches Hack.me Free Virtual Labs for Web Application Security
EH-Net EXCLUSIVE: eLearnSecurity Officially Launches Hack.me WebApp Labs
Imagine a security virtual lab that is run by the community for the community... Free of charge! This is Hack.me. Hack.me allows web application security researchers and instructors to create and share vulnerable web applications for testing and educational purposes. Users will be able to run and practice offensive techniques against always new vulnerable web applications provided by the community. Practicing the OWASP Top 10, testing vulnerabilities against CMSs, verifying the latest exploits against COTS will be just a click away. Hack.me is completely FREE for all to use, accessible online and hosted in the cloud. Based on the Coliseum Framework, every vulnerable application created on hack.me is run on the fly in an absolutely safe and isolated sandbox. Watch this webinar from October 2012 where Armando Romeo, founder of eLearnSecurity backing the Hack.me project, and Thomas MacKenzie, web application security specialist, unveiled the project and launched it to the world.


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Located in Little Italy, Apollo's menu sets out 18 different themes (such as mushrooms, seafood, cocoa beans, etc.). For each theme you order, four different variations of it will be brought to your table. When I went recently with friends, we started with a foie gras theme, then followed with a seafood theme and another mysteriously called "Memories of my childhood in Naples." For dessert, we went for the "chef's inspiration." In all, 21 delectable dishes came to the table. Heaven!
And, you know what is the frosting on the cake, so to speak? Apollo is one of Montréal's many BYOW (bring your own wine) restaurants. I'll be writing more about these soon, but essentially it means that you bring your own bottle, with no additional corking fee. Fantastique, no?
Expect to spend about $130 (before taxes and tip) for two people.
6389 St-Laurent Blvd.
514 274-0153
Business Hours:
Tuesday to Saturday 5:30 pm to 10 pm
Closed: Sunday, Monday


text: I checked my hives the other day and noticed a large amount of bees(equivalent to a 3pound package) under one of my hives. They are located right under the solid bottom board right in the front. This is one of my strongest hives that is doing very well. I smoked them lightly and none of them retreated into the hive. After more inspection I noticed they had a large amount of comb built with nectar. I did not see any larva or brood. This all happened in a matter of days. Is this a swarm from the hive above? Should I try to capture them?


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|GTA V Latest News | #GTAV | #GTAOnline
2008 GTA IV Giveaway winners announced!
Grand Theft Auto IV - General News | @ 01:20 PM MDT | By rappo
Our GTA IV Giveaway has finally come to a close, and we have selected our eight prize winners out of the 1500 users that entered. After spending one hour cutting out over one thousand small pieces of paper, taking two hours to write down all the names, getting three paper cuts, suffering from several headaches, and pulling names out of the
If you're not on this list, don't worry because at GTAGaming everybody wins something! If you didn't get any physical prizes, you get the best gift of all: an e-Hug. So to those that didn't place for a prize, thanks for your support... *hug*. In all seriousness, though, this definitely isn't our last giveaway, so be sure to stick around for future competitions and raffles!
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Stay connected with us to get the latest health and fitness news, innovative workouts, healthy recipes and wellness tips.
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Red beets and golden carrots look especially festive in these zesty horseradish-and-bacon-flecked cakes. Avoid parsnips, which need to be cored, in this recipe, as trying to shred the smaller cored pieces might result in nicked knuckles. Try the pancakes with seared steaks or make them bite-size for a beautiful appetizer.
Nutrition Profile:
Diabetes Appropriate
Healthy Weight
Heart Healthy
High Fiber
Low Calorie
Low Carb
Low Cholesterol
Low Sat Fat
Low Sodium
Serves 6
Prep Time 30 min
Total Time 45 min.
Step 1
Preheat oven to 400°F. Coat a baking sheet with cooking spray.
Step 2
Whisk egg, flour, scallions, dill, horseradish, salt and pepper in a large bowl. Stir in vegetables and bacon (if using).
Step 3
Heat 2 teaspoons oil in a large nonstick skillet over medium heat. Cook 4 pancakes per batch: place about 1/4 cup vegetable mixture in a little of the oil and press with the back of a spatula to flatten into a 2- to 3-inch pancake. Cook until crispy and golden, 1 1/2 to 3 minutes per side. Transfer the pancakes to the prepared baking sheet. Continue with 2 more batches, using the remaining 4 teaspoons oil and vegetable mixture. Transfer the baking sheet to the oven and bake for 15 minutes. Serve garnished with sour cream, if desired.
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by Chicken Skin April 06, 2004
The state or likeness of being beyond godly-- more than 'epic' or 'uber'. Being siddy denotes the possibility of any lower status than itself and can be considered the pinnacle of spiritual enlightenment or physical achievement in life; it can be compared to reaching Nirvana, one really good high, or sexual gratification.
by FeatherHeavens July 21, 2009
A guy who is down to earth, sweet, smart and really tall. He can be serious and blunt from moment to moment. Most of the time he is funny and nicely-honest. Siddy's tend to be more feminine then masculine, making them ideal for a girl who is looking for someone who understands them clearly. Siddy's are one of the best types of guys to be around.
by Niikozilla April 01, 2011
by flakiki June 13, 2005
by Kinsolian August 31, 2004
a bum. a poor bum who lives on the streets who always wears unwashed pink spotty socks and carries a whip. Always treat a siddy with respect or she'll fart on you. Whos head sounds hollow when she whacks it after having eaten parsnips.
by anonymous22222222222222 May 17, 2008
The vengeful act of crapping on a lover's chest while they sleep.Buy the plush


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AT&T Joins U.S. TV Revamp With $48.5 Billion DirecTV Deal
AT&T Inc. (T) plans to buy DirecTV (DTV) for $48.5 billion, gaining more than 38 million video subscribers at home and in Latin America and stepping up an acquisition-fueled overhaul of the $110 billion U.S. pay-TV industry.
AT&T will pay $95 for each share of DirecTV, split between $28.50 in cash and the equivalent of $66.50 in stock, the companies said yesterday. That's 10 percent more than DirecTV's closing price on May 16. Including net debt, the deal values the largest U.S. satellite-TV company at $67.1 billion.
Randall Stephenson, chief executive officer of AT&T since 2007, is embarking on the company's largest takeover in eight years to bulk up after competitors Comcast Corp. (CMCSA) and Time Warner Cable Inc. (TWC) announced their own merger, accelerating consolidation across the communications industry. The purchase gives AT&T a national satellite-TV provider to combine with its existing packages of wireless, phone and high-speed Internet service.
"Strategically, this makes a lot of sense for AT&T," said Jan Dawson, an analyst with Jackdaw Research in Provo, Utah. Gaining a satellite-TV provider "lets them go national with a video offering that matches their wireless reach."
For Comcast and AT&T, getting bigger means greater negotiating power with video providers, from traditional cable networks to online streaming services. Their deals are part of a wave of merger activity in the telecommunications industry as companies seek to control the technology consumers use for entertainment and information. Verizon Communications Inc. bought out Vodafone Group Plc's stake in their wireless venture for $130 billion this year. And Japan's SoftBank Corp., which paid $22 billion for control of Sprint Corp. last year, is now eyeing an acquisition of T-Mobile US Inc.
Bolstering Broadband
AT&T fell 1 percent to $36.38 at the close in New York while DirecTV declined 1.8 percent to $84.65.
The agreement was approved by both boards, and the companies expect the deal to close within 12 months, pending regulatory review and approval from DirecTV's shareholders. To help with antitrust approval in Latin America, AT&T said it plans to divest its 8 percent stake in America Movil SAB. (AMXL) Buckingham Research Group put the odds of regulatory approval at about 90 percent.
DirecTV, which doesn't have its own phone service or a competitive Internet offering, was under pressure to find a partner as more viewers go online for video and the pool of traditional pay-TV customers shrinks in the U.S.
With the transaction, AT&T said its high-speed broadband network will cover 70 million customer locations. That was one of the reasons for the deal because it helps customers watch TV on any device, DirecTV CEO Mike White said in a phone interview.
Mobile Video
"Randall and I have had a relationship for a number of years," White, 62, said. "Over the last year, things began to change with technologies -- AT&T started to be able to offer more broadband and better broadband. With it comes a continuing evolution for mobile video."
In the joint phone interview, Stephenson, 54, highlighted DirecTV's relationships with content providers and head start in setting up a package of Internet-delivered channels similar to a pay-TV bundle, known as over-the-top service.
DirecTV will still be based in El Segundo, California, and its service will be available on a standalone basis for at least three years after the acquisition closes.
The companies said the deal will add to free cash flow and earnings per share within 12 months of closing, and cost savings will top $1.6 billion on an annual basis.
'Industry Redefining'
AT&T plans to finance the cash portion of the deal with cash on hand, the sale of non-core assets, committed financing facilities and opportunistic debt market transactions. AT&T had a market value of about $191 billion as of May 16 and had total debt of about $80 billion and cash and equivalents of $3.6 billion at the end of March.
Including debt, the acquisition is AT&T's third-largest deal on record, behind the purchase of BellSouth for $83 billion in 2006 and the deal for Ameritech Corp., which closed in 1999, according to data compiled by Bloomberg.
The deal is also the third-largest for the communications industry in the past year, ranking after Verizon's $130 billion deal for the rest of its U.S. wireless venture and the pending $68 billion purchase of Time Warner Cable, the data show.
At the $67.1 billion deal value, which includes debt, AT&T is paying 8.15 times DirecTV's earnings before interest, taxes, depreciation and amortization in the 12 months through March, according to data compiled by Bloomberg. That's in line with a median multiple of 8.11 times trailing 12-month Ebitda for cable and satellite companies over $1 billion in the past five years, the data show. Comcast offered about 8.6 times Ebitda for Time Warner Cable, the data show.
Regulatory Approval
Comcast's plan to acquire Time Warner Cable will create an even bigger provider of both TV and Internet in the U.S. In March, AT&T's Stephenson called the Time Warner Cable takeover an "industry-redefining deal."
One of the main questions about the potential deals is whether regulators will allow them. Comcast's takeover of Time Warner Cable hasn't been approved yet. A merger of DirecTV and satellite-TV rival Dish Network Corp. (DISH) was blocked more than a decade ago. AT&T, the second-biggest U.S. mobile-phone carrier, had to abandon a purchase of Deutsche Telekom AG's T-Mobile U.S. unit in 2011 in the face of antitrust opposition.
Unlike Comcast's acquisition of Time Warner Cable, AT&T's purchase of DirecTV would eliminate a choice for pay-TV customers in some markets because AT&T's U-verse landline video service competes with DirecTV. DirecTV has 20.3 million U.S. customers, while AT&T's U-verse TV service had about 5.7 million customers at the end of the first quarter.
America Movil
White and Stephenson confirmed AT&T will offer both U-verse and DirecTV in markets where the products overlap. If this becomes a regulatory issue, AT&T could theoretically stop offering U-verse TV and only offer DirecTV along with U-verse broadband, but no decisions have been made because the companies didn't feel the need to offer this condition yet, according to a person familiar with the matter.
To facilitate antitrust approval in Latin America, AT&T will sell all of its L and AA shares in Carlos Slim's America Movil, and its designees to America Movil's board will tender their resignations immediately. A press official for America Movil declined to comment.
Stephenson said he visited recently with Slim to discuss his plan to do the deal and reaffirmed they had a strong relationship.
'Unprecedented Concessions'
America Movil is a direct competitor to DirecTV in countries including Brazil and Colombia. DirecTV's Latin America operation includes Mexico, where it has a minority stake in Sky Mexico, controlled by Grupo Televisa SAB, one of America Movil's biggest rivals.
Selling the stake in America Movil will reduce AT&T's earnings by about 5 cents a share, according to the statement. AT&T now projects 2014 per-share earnings growth at the low end of its earlier forecast for a "mid-single digit" increase.
Stephenson said that he's offering "unprecedented concessions" to help ease the regulatory review process. One of those concessions is freezing prices for three years for DirecTV's TV service and wireline IP broadband service.
"There are sensitive areas for sure but they are all manageable," he said in the interview. "We think this will pass regulatory muster."
Breakup Fee
AT&T won't owe a breakup fee to DirecTV if the deal is blocked by regulators on antitrust grounds, the CEOs said in the phone interview. In AT&T's failed effort to acquire T-Mobile, the company paid $3 billion in cash plus wireless frequencies and a roaming agreement.
DirecTV will pay AT&T a breakup fee of $1.445 billion if it instead agrees to be sold to another company, the pay-TV provider said in a filing today. Both companies may call off the combination if it's not completed by May 18, 2015, according to the filing. That deadline may be extended to Nov. 13 of next year under certain circumstances, DirecTV said.
AT&T said it will commit to abiding by the principles of net neutrality for three years, meaning it won't block websites or selectively speed up or slow down Internet traffic.
'Merger Mania'
Consumer groups have already started speaking out against the merger.
"The captains of our communications industry have clearly run out of ideas," Craig Aaron, CEO of advocacy group Free Press, said in a statement. "Instead of innovating and investing in their networks, companies like AT&T and Comcast are simply buying up the competition. These takeovers are expensive, and consumers end up footing the bill for merger mania."
DirecTV will give AT&T a pay-TV business that's expanding in Latin America. It has 18.1 million subscribers there, including Sky Mexico, of which it owns 41 percent.
DirecTV is also getting U.S. customers to pay increasingly higher monthly bills by offering exclusive content such as the National Football League Sunday Ticket package and products such as Genie, a multiroom digital video recorder.
Sunday Ticket
DirecTV's White said today that the company has been in talks with the NFL and is still confident it will renew its deal for NFL Sunday Ticket. The takeover could hinge on those negotiations, according to a regulatory filing today. If the Sunday Ticket rights aren't renewed on the terms discussed between AT&T and DirecTV, then AT&T can call off the merger, the filing shows.
DirecTV generated $2.6 billion in free cash flow last year, cash that AT&T can use going forward to help support dividend payments. AT&T pays a quarterly dividend of 46 cents a share.
When the deal closes, DirecTV shareholders will own 14.5 percent to 15.8 percent of AT&T stock, on a fully diluted basis, based on the current number of AT&T shares outstanding.
DirecTV had also drawn merger interest from Dish Network Chairman Charlie Ergen, people with knowledge of the matter said in March. While a DirecTV merger is tempting, the satellite-TV rival is too expensive to pursue, Ergen said this month on a conference call to discuss first-quarter earnings.
AT&T's $95-a-share offer represents a premium of 30 percent over DirecTV's share price in late March, before Bloomberg News reported Ergen's interest in a merger. AT&T surfaced this month as a possible acquirer, driving DirecTV shares higher.
DirecTV Rally
A deal with DirecTV shows that AT&T has turned its attention back to the U.S. market since the Time Warner Cable takeover was announced. AT&T had previously explored wireless opportunities in Europe, such as acquiring Vodafone.
Stephenson said in the statement that DirecTV is the best option for AT&T because it brings the top brand in satellite-TV and a fast-growing business in Latin America. He declined to comment on Vodafone when asked about the U.K. company in an interview.
DirecTV shares were already up 25 percent this year.
One of the biggest beneficiaries of DirecTV's rally this year is Warren Buffett's Berkshire Hathaway Inc., thanks to a stake built by his deputy stock pickers at about half last week's price. Berkshire had about 34.5 million shares as of March 31, a regulatory filing showed last week.
The deputies, Todd Combs and Ted Weschler, issued a statement in support of the deal.
"This is a terrific transaction for all involved: Enhanced choice for consumers coupled with increased value for both AT&T and DirecTV shareholders -- a natural," they said.
Goldman Sachs Group Inc. and Bank of America Corp. served as financial advisers for DirecTV, while Weil, Gotshal & Manges LLP, Jones Day and Wiltshire & Grannis LLP acted as legal advisers. AT&T was advised by Lazard Ltd.
To contact the reporters on this story: Alex Sherman in New York at email@example.com; Scott Moritz in New York at firstname.lastname@example.com
To contact the editors responsible for this story: Sarah Rabil at firstname.lastname@example.com; Mohammed Hadi at firstname.lastname@example.com Crayton Harrison, James Callan


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These Pioneer 12x12 3-ring binders have a padded sewn leatherette cover with a label holder on the spine and metal corners to prevent accidental damage. Add pages to make a great scrapbook.
- Holds most sheet protectors up to 12" x 12" including Pioneer 12x12 Memory Book Refill Pages, 4x6 Pocket Refill Pages, Print File CD storage pages plus most other 3-ring photo pages
- Standard 3-ring binder spacing with extra large 2-1/2" D-rings can accommodate approximately 85 pages (not included)
- Rounded spine features 1-1/8"W x 1-3/4"H label holder
- Overall dimensions: 15-3/4"W x 13-1/16"H x 3-1/2"
- 3-3/4" x 3-3/4" photo frame on cover
- Archival, acid free, photo safe
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Jul 1, 2014 | By Janice
Love these covers. They are the best for my scrap booking. Pages glide over rings. I will be purchasing more! Price is awesome!
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Beautiful, sturdy 12 x 12 album
Dec 1, 2013 | By SC
I really love this album. It seems to be very sturdy and well-made (the metal plate with the rings is riveted to the spine - not glued like some albums. I like the reinforced metal corners and extra large rings. It easily holds 40 or more pages (80 sides). The spine has a place for an insert (it would be nice if it had a piece of plastic to protect the insert. I made my own from a page protector.) The cover has a place for an insert as well. To personalize, I bought an engraved plaque for under the insert. I highly recommend this album.
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12x12 Three Ring Binder
Sep 18, 2013 | By Donna
I needed a large 3 ring binder for the very oldest Confirmation pictures for our church. This Binder was just the right size, and is well made. I was glad to find what I needed.
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3 ring binder
Mar 7, 2013 | By Loyd McBride
Will serve our purposes just fine.
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T-12JF photo binder
Dec 29, 2012 | By JJ
Have bought many of this particular photo binder, accomodates many thick scrapbook pages, very economical, yet extremely durable, love it, my favorite...wish there were more than 3 colors, however
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SUNY Plattsburgh, in 2007, became the first college or university in the United States to offer a Bachelor of Arts minor program in Quebec Studies. The 18-hour Quebec studies minor is a multidisciplinary program for undergraduate students seeking to combine it with a major in a complementary field. Students in such majors as Canadian studies, political science, international business, marketing, history, French and many others available at SUNY Plattsburgh find this minor to be an attractive asset as they secure careers in the private and public sectors or pursue graduate studies. Students in the minor program must complete at least one three-credit French course and may complete an internship or an independent study project on Quebec. Quebec studies content courses offer a rich array of comparative perspectives through which to gain a deeper understanding and appreciation of Quebec society.
For further information about Canadian studies at SUNY Plattsburgh, please contact:
Dr. Christopher Kirkey
Center for the Study of Canada 202
Phone: (518) 564-2086
Email: firstname.lastname@example.com


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Facebook and Twitter profile pictures allow friends, neighbors and strangers to judge us on paper. Does yours say that you're an animal welfare expert?
by Lucas Sjostrom, Associate Editor, Hoard's Dairyman
We're in a constant fight for face time with consumers against our animal rights foes. Animal rights activists are very good at messaging. Using donated resources to hire a professional staff, their war chests tower over that of animal agriculture. According to HumaneWatch.org, the Humane Society of the United States probably has about 450,000 active supporters and a budget of just under $122 million (http://humanewatch.org/index.php/site/categories/category/the_best_of_humanewatch/).
Their high-quality messaging doesn't stop at television advertisements and mailing campaigns. Think of the pictures you've seen of animal rights leaders. They fit in two main categories; posing with an animal in the picture and professional dress. Sometimes they are both.
Yesterday, I spoke to the Minnesota Agricultural Ambassadors Institute in Red Wing, Minn. About 40 young agriculturalists serving as various livestock and crop ambassadors are taking part in the three-day leadership-training event.
During part of my presentation, I played a game with the attendees using pictures. On the screen I put head shots of animal rights activists, animal welfare specialists and a few farmers. Then, without telling the attendees who was represented in the head shots, I asked them to make a judgment of the people in the pictures based on what they could see about their knowledge of animal welfare and food safety.
Based on the pictures, the animal rights activists received pretty high marks. The attendees commented that they "obviously cared about animals" and "worked on a farm." One of them was holding a dog and the other one was petting a sheep.
Our agricultural leaders looked professional, "political" (standing in front of a flag) and educated. Those aren't bad terms, but wouldn't you rather be associated with animals? The picture that received the best marks was a dairy farmer standing with a cow in his parlor. The student leaders commented that he looked like a hard worker, a farmer and a person who cares for animals all day.
When picking your next profile/timeline picture on Facebook, LinkedIn or Twitter, think about the message you're sending across. Can people look at you and instantly give you credibility in the area of animal welfare? If not, it might be time for a status update.
Click the icon to subscribe to HD Notebook and get the blog sent to you.


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Our Products
Dandelion Scarf Pattern
Road Trip Hat Pattern
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Through the Rabbit Hole Baby Sweater Pattern
Until December 31st when you buy this pattern you get the Through the Rabbit Hole Double sided Hat Pattern FREE!Through the Rabbit Hole Baby Sweater is an adorable top down baby sweater with a side button band to get on the wee one easily. With a simple stripe detail you can't go wrong for your own or as a gift! Knit with Wonderland Yarns, 1 Skein Mad Hatter - Dream World, 1 Color pack of Mad Hatter- "Lights Part 1" Needles & Notions: US size 4 or 5, 16" circulars and double points (which ever gives you gauge) Gauge: 6sts/1" inches in pattern Sizing: 3 month(6 month, 12 month, 18 month)
Tweedle Dee and Tweedle not- so-Dumb Baby Sweaters
Yarn: Wonderland Yarns "Mad Hatter" sport weight yarn, 4 oz skein, 344 yards; 100% superwash merino: 1 skein, (MC) AND "Mad Hatter" sport weight yarn, 5 oz Mini-Skein Pack, 430 yards; 100% superwash merino: 1 pack (CC1-5) (note on Tweedle Not-so-Dumb, CC1 is not used) Samples shown knit in MC "Mock Turtle" and "Dark Rainbow, part 2" Mini-Skein pack
Needles & Notions: US size 3, 16" circulars and dpn AND US size 1, 16" circulars and dpn (or size to get gauge), darn- ing needle, stitch markers (4), waste yarn or extra needles to hold sleeve stitches when not being worked Gauge: 24 sts = 4 inches in stockinette Sizing: 3 month (6 month, 12 month, 18 month)


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I need to write a small script (pref. Python) that can detect old windows NT 4 boxes in a mixed large windows network. Result should just be a name or a IP if it is a NT4 box. The script should be able to run without user account.
Any ideas of what to detect verify on in relation to the possibilities in python/perl?


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Item ID: 88483
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a place for zinesters - writers and readers
Views: 7
the wording of some of this is kind of weird...i don't mind being public about being an abuse survivor, but it rubs me the wrong way when people hear that & assume that i must be "strong," or even stronger than i would have been had the abuse never occurred. i would prefer not to be "applauded" for having been abused. it's something that should have never happened. words like "applaud" & phrases like "abuse makes survivors stronger" almost veers into acting like abuse was a good thing in some weird, twisted way, which i know is not your intention.
i guess i'd just reconsider the phrasing to be a little more sensitive to abuse survivors. i certainly would not use the word "victim" at all in a call for submissions.


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Pedro Garcia
A collection of gorgeous footwear in every style imaginable, Pedro Garcia is a shoe lover's dream label. The brand was set up in an Alicante workshop in 1925, and is now headed by Garcia's grandchildren, Pedro and Mila. Bring every look to life with suede wedge pumps and crystal-embellished sandals.


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Full Year 2012 - Rachel K. Johnson, PhD, MPH, RD
The School Day Just Got Healthier!
By: Rachel K. Johnson, PhD, MPH, RD, Bickford Professor of Nutrition and Professor of Medicine at the University of Vermont and Member of the President's Council on Fitness, Sports & Nutrition's Science Board
This fall, school nutrition programs underwent major changes that improve the nutritional quality of school lunches nationwide. The media has been filled with stories about the new menus, which feature more whole grains, fruits, and vegetables in items such as sweet potato fries, whole-wheat tortillas and black bean and corn salsa.
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Challenge your muscles by mixing up activities; trying new things keeps it interesting!


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George Washington Bridge lanes reopen after fatal crash [video]
Mobile users, click here to view video
The driver of one of the tractor-trailers involved in an early-morning crash on the George Washington Bridge has died, and the cleanup and investigation have resulted in a massive traffic jam.
All lanes have reopened, said Port Authority Police Capt. Ron Shindel, the bridge's commanding officer, though the shutdown caused a domino effect, with traffic backed up for miles along alternate routes.
The identity of the driver has not yet been released.
The crash occurred on the bridge's eastbound upper level around 2:05 a.m. on the New Jersey span, Port Authority spokesman Joe Pentangelo said in an email.
The other driver was visibly shaken up and transported to Englewood Hospital and Medical Center with minor injuries, agency officials said.
One of the tractor-trailers was carrying food items; the other contained appliances, Shindel said. Both were fully loaded.
The Bergen County Prosecutor's Office also is investigating the crash.
Police have no reason to believe a reported suicide on the bridge at 2 a.m. is related to the crash, Shindel said. The incidents were more than 3,000 feet apart on the bridge.
Officials reopened one eastbound upper lane around 6 a.m., but the remaining lanes were closed for more than nine hours until officials had removed the victim's body and the trucks by 11:45 a.m. The cleanup was delayed because special equipment was needed to separate the trucks, Shindel said.
Cars crawled along the bridge's lower level into New York while vehicles could enter New Jersey by the bridge's upper and lower westbound lanes. Trucks and buses, however, have been banned from the lower level since the Sept. 11, 2001, terrorist attacks.
A ripple effect of delays followed, with motorists inching along for miles around as they sought alternate routes into and out of the city.
The accident came just days before the Port Authority will close the bridge's three upper level lanes for 12 weeks during overnight hours for construction, beginning June 16.
The George Washington Bridge is one of the busiest bridges in the world, crossed by more than 100 million vehicles a year.
The Associated Press contributed to this story. Email: email@example.com


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That was funny so I laughed.
Bryce: "a priest, a rabbi, a bear, two guys, a nun, a horse and a guy with a 12" piano player on his shoulder all walk into a bar the bartender looks up and says 'What is this, a joke?' ". Elizabeth: "twfsil."
by lizardbreath June 19, 2013


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Over the years we've featured the amazing sandwich bag art of a number of devoted parents here on GeekDad, and here's another one to add to that fine group of creative lunch makers. I've been seeing these funny little pictures pop up in the GeekDad Flickr group for a while now (you do know we have a Flickr group where you can add any of your geeky snaps, right?), and so I contacted the artist to find out a bit more. I can just about find the time in the morning to get together two slices of bread with something in between and pop them in my daughter's lunchbox, so I was interested to see how a 'pro' does it.
The creator of these plastic bag masterpieces is David Laferriere, a designer and illustrator from Massachusetts. He has two sons and every morning he makes their sandwiches, but before he packs them away he grabs his Sharpies and draws something on the bags for the kids to discover at lunchtime. Turns out he's been doing it for over four years now, creating over 1,000 individual works of art. Read on to find out how it all came about. Continue Reading "A GeekDad's Daily Creative Boost – Sandwich Bags!" »


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Web development may be distinguished from traditional software development by descriptive terms such as "slam it and jam it," "FAD--Frantic Application Development," or "Wild Web Developer." These phrases from Glass' column help us understand the new challenges faced by test and QA people who are assigned to Web projects. In this column, Glass identifies many of the new aspects of testing that come with the advent of Web software.
I recently had a wonderful experience at an industry conference and learned some interesting things I thought I'd share with you. Usually I hate going to conferences on the topic of testing and quality assurance (they can be so boring when under-qualified, over-hyped, or overly-academic people get up to speak). However, I recently returned from the Practical Software Quality Techniques (PSQT) conference in Bloomington, Minnesota, held in conjunction with the PSTT conference (where T=Testing replaces Q=Quality). And, I am even more happy to say, the P=Practical word in the title was particularly well chosen. Presentations were by "been there, done that" kinds of people.
I went out of my way to choose sessions on Web application development (there were eight parallel tracks), mainly because I don't know much about Web development. My chief interest was to what degree Web development differs from traditional software development. The answer I learned, partly to my surprise, is "plenty."
What's different about Web application development? Web application development tends to be:
- requirements-free: There are seldom any stated requirements at the outset of a project. (One speaker described that phenomenon, only partly in jest, as "Specs? We don't need no stinkin' specs!")
- rapid-development: There is seldom time to do anything more than what one speaker called "slam it and jam it," using a process he called "FAD--Frantic Application Development."
- short fuse and relatively small: Most projects are expected to last about three months, using a maximum of four people.
- testing-primitive: There are few generally accepted processes, and the tools that are available often don't fit the problems well.
- user-intimate: Although you never meet your users, they are only a mouse click away from letting you know what they don't like--and from going over to the competition.
- a "living project" (two speakers used this term): Maintenance, usually by the developer, is a "must," and in fact "all products are in permanent beta test" (modifications are ongoing).
- performed with limited management support: Most managers think Web development is easy.
- highly aware of performance: Performance is vital--and extremely unpredictable.
- concerned with content: Content is king; it doesn't matter whether the application is "pretty" or not, if the content isn't interesting or useful.
- a whole new field: Developers are more "Wild Web developers" than software professionals.
In fact, that last item is key to understanding the difference between the Web and traditional software. One speaker expressed this difference very well, saying, "We've moved back two decades in testing approaches" (that is, no one is building the notion of Web applications testing on the lessons learned from the history of software testing), but went on to say "I'm not sure that traditional approaches will ever be applied." In another session, the issue became even more clear. Is it pure backwardness to build Web applications without requirements, or is it simply true that in any rapidly evolving discipline, it is impossible to know what the requirements are until the first (several?) prototypes are built? And in the absence of firm requirements, isn't it impossible to perform the rudiments of traditional testing and quality, such as requirements-driven testing? As the Web applications field matures, it will be fascinating to see what comes of these issues.
What characterizes a Web application? Andrea MacIntosh of QA Labs, Inc., said that the typical architecture is a browser tied to a Web server tied to an application server tied to a database. And what characterizes Web applications testing? The same speaker said that it's about multiple environments (you can't test a new version of a site on the live site), multiple platforms (you can't necessarily control


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American Council on Exercise4851 Paramount DriveSan Diego, California 92123
Receive unique offers and information on specialist programs, workshops, free webinars and more.
Making a commitment to change can often be a hurdle for people – especially when it means giving up their favorite foods or altering their everyday routine. Too many times, personal trainers have to deal with the "I hate change" attitude in their clients. In this webinar by Jonathan Ross, you'll learn how to turn negative attitudes into a source of motivation by asking the right questions at the right time. Connect your client's goals with their values and help set goals they can attain, and you'll help them become more confident in their own success.
You will learn:
Easy to understand, lots of great information to help clients with changing thoughts to change behavior. Practical information to guide clients to understand the ""why" of their changing behavior so it sticks. Very helpful for those planning on being Behavior Change Specialists.
I liked the presenter and the material. Quiz questions were poorly written (confusing). I got them all correct but did not like the wording (missed the last one cause my computer skipped it - I am having HUGE issues with the quizes not saving and continuing.
How Would You Rate This Product Out of 5 Stars?
The American Council on Exercise reserves the right to discontinue the sale and/or support of any continuing education course at any time, in order to cancel, correct, or update content based on current industry standards, guidelines, and/or technological advances. Notification will be given 6 months prior to expiration to allow for course completion and no refund will be given for expiring courses.


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Why Software Companies Should Slash Their Prices
Posted on 4th Feb 2010 at 11:09 by Antony Leather with 26 comments
How do you compare one piece of software to another? Features? Price? The space it takes up on your hard drive? How would you predict how well a product might sell and factor that into the pricing?
For most of us it comes down to cold hard cash and whether we can find something that's as good or better, for less, or even for free. However, only a handful of companies have grasped the fact that if you lower the price of software enough, sales will skyrocket so high, they'll make many times more profit than if they priced it twice as much, however popular the software may be.


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Home › Forums › General Forums › General Lightweight Backpacking Discussion › Tarps Above Timberline
Jun 21, 2010 at 7:28 pm #1260393
Dale MurphyMember
@getlightmurphyLocale: North Central Texas
I will be spending 7 days in the Weminuche in early July. One of my compatriots has spoken to a Ranger who is supposed to be an avid hiker and according to the Ranger we are going to have a tough time with tarps above timberline because the ground will be too hard for stakes. Is this a legitimate concern and should we abandon the tarps for tents?Jun 21, 2010 at 7:50 pm #1622174
Mat TallmanMember
@wehtamLocale: Midwest
For the record, I've never camped above treeline in any manner.
That being said, an inability to sink a stake seems like an odd reason for you not to be able to use any particular shelter. Even a free-standing tent would need to be firmly staked to the ground above treeline, due to the increased propensity for high winds.
If the ground is rocky and hard, you can use rocks in place of stakes.
I would be inclined to believe that the less wind-resistant nature of most tarp setups, in comparison to some tents, would be a tougher obstacle above treeline.Jun 21, 2010 at 9:31 pm #1622224
Dan MagdoffBPL Member
@highsierraguyLocale: Northern California
I do quite a bit of backpacking above tree line in the sierras. I have been thinking about getting a tarp and that is a concern of mine too. In the sierras if you are above tree line…you are pretty much ion granite and cant use stakes at all. However, like said above….I think you could easily use some parachute cord and tie to rocks where stakes would be needed.Jun 22, 2010 at 5:08 am #1622285
Dale MurphyMember
@getlightmurphyLocale: North Central Texas
Thanks for the input. I was hoping that somebody that had been above timberline with an ultralight shelter would post about there wonderful experience and help ease my paranoia! The hardest part of getting light is the anxiety and second guessing.Jun 22, 2010 at 8:25 am #1622322
Tim HeckelSpectator
@thinairLocale: 6237' - Manitou Springs
Not really. Making a blanket statement like that is totally absurd.
If you can stake a tent you can stake a tarp. You will have to be careful about site selection of course.
There are other reasons I personally wouldn't take a tarp, but I don't have a lot of tarp experience.
If you have enough experience with tarps in high winds, driving rains, mosquitos, and snow then you *might* be ok.
Depending on where and when you are going I might see you there. I'll be in the Weminuche starting this Saturday for 10 days. I'm using a tarptent the first few nights (at treeline), then switching to my Akto for the remainder of the trip (no I'm not carrying both, it's a long story).Jun 22, 2010 at 8:54 am #1622329
Mark RegaliaBPL Member
@markrLocale: Santa Cruz
I camp a lot above tree line. Finding a spot that is smooth, has good drainage, runoff is not routed through it AND allows staking is a trick. I gave up and went to a free standing tent. My particular set of circumstances was such that I wasn't saving any weight anyway. I don't use hiking poles, have dogs that when wet go straight for my sleeping bag, and then there are the mosquitoes.
No reqrets, loving having a tent which shelters me and my dogs without my having to share my personal space with wet dogs and keeps out the mosquitoes.Jun 22, 2010 at 9:00 am #1622333
John VanceBPL Member
@servingkoLocale: Intermountain West
+1 on the above. I too gave up since I tend to spend most of my time above or at timberline and wasn't really saving much if any weight. If it's just a couple of nights and I am confident in the weather being nice, I just cowboy camp with a small 3mil plastic tarp and no bivy. Most of the time I am using a tent to get away from the wind and/or bugs, either a BD Skylight or Hilight.Jun 22, 2010 at 9:01 am #1622335
Dont WanttoMember
I'm not sure I understand why a free-standing tent is better above treeline in Colorado.. is it impossible to stake it out above treeline but not below? And a free-standing tent is OK above treeline without staking out?
I'm hoping to using a Tarptent Cloudburst for my thru-hike of the Colorado trail this year and was hoping to do a few nights above treeline in the San Juans if the weather permits..Jun 22, 2010 at 9:11 am #1622341
David OlsenSpectator
@owareLocale: Steptoe Butte
For Outward Bound and similar schools, all they take
are tarps for shelter. In the Sierra Nevada, Wind Rivers
North and South Cascades, with some trips mostly above
tree line, they use large group tarps and small solo tarps.
Site selection is a big deal. You won't find them camping
on exposed ridges if at all possible. They will look
for large boulders for wind breaks, use rocks as big as
can be carried instead of stakes, sleep on granite slabs
to avoid damaging vegetation and to stay clean (no mud
on your sleeping gear). Sometimes a rock wall can be built
for a wind shelter, tho pulling rocks out of the dirt is
avoided as these often shelter insects.
Tho I don't bring trekking poles or tarp poles myself, the
students are issued tarp poles to make tarp set up easier
when there are no trees.
It takes time, effort and ingenuity to use tarps above
treeline. The discipline that is developed is part of the
learning process in these school outings.
But, you hike your own hike and may want to spend your time
cooking, climbing or taking pictures instead of tarp craft.
A light tent may be more suitable for your needs if so.
One final consideration about tent stakes. In some highly
used areas they are discouraged due to the damage in some
soil environments. In those cases, shelters that require
few or no pegs are preferred or required by the land
managers.Jun 22, 2010 at 10:34 am #1622379
Nick GatelBPL Member
@ngatelLocale: Southern California
Tarps are going to give you more pitching options, and you can sleep in places where a tent is not going to fit. As Dave mentioned, site selection is critical. Also, if you use a tarp often, then pitching it does not take long.
If weather requires a shelter, I try to go below treeline anyway, especially in the summer where thunderstorms are frequent. I don't want to be the highest point on the ground.
But if weather is good, the tarp stays in my pack. Nothing better than a full panorama of the sky from your bed, or the view from a high treeless place.
IMO, it doesn't matter whether you use a tarp or tent above treeline, but your securement methods are often different that other places, and you need to be competent with either type of shelter.Jun 22, 2010 at 12:47 pm #1622416
bryan englishMember
@apoxtleLocale: so cal.
i've used a tarp many times above treeline. actually more than a tent. i usually just tie my guylines to rocks. i don't think you would have a problem and wouldn't worry about it. i'll actually be using it up on top of san gorgonio on the 4th of july. fireworks look pretty cool thousands of feet below.Jun 22, 2010 at 2:04 pm #1622443
Mark RegaliaBPL Member
@markrLocale: Santa Cruz
You certainly can use a tarp above treeline. I just found that it was more trouble than it was worth, especially considering that I was not saving any weight. Actually I never took to tarps at all. I seem to have really bad weather luck and keeping my bag dry with two wet dogs in camp is a problem. There is a seldom described natural force of attraction that describes how the attraction between a dog and your down sleeping bag is directly proportinally to how wet the dog is. My Big Sky Evolution 1P with dual vestibules is just too perfect of a solution for my needs.
If I was below treeline, after mosquito season, and not expecting any rain, and I knew I would have an over head branch to suspend my tarp from (I don't carry any poles) then a tarp sounds good, but then I wouldn't need a shelter.Jun 22, 2010 at 2:15 pm #1622446
Nick GatelBPL Member
@ngatelLocale: Southern California
Tarps are not for everyone!!
However, my "double size" BPL Nano at 5 oz, is much, much less weight than any tarp tent.
I would not recommend anyone use a tarp like this above treeline, unless they have a lot of experience with tarps.
Another light option is the GG SpinnTwinn at under 9 oz. Similar size as the Nano, but about 1/2 the price with Spinaker material.Jun 23, 2010 at 4:35 am #1622628
Steven McAllisterBPL Member
@brooklynkayakLocale: South West US
Yes, tarps require experience. Lots of tie-outs are a plus.
Tarps do have some advantages above treeline. They can be more flexible. A tarp will allow you to make shelter between rocks(or other objects) where a tent would not fit. The rock(s) can become part of your shelter structure.
In the worst case you could roll up in it like a burrito if trapped in a tight spot during lightning storm.
You can pitch a tarp low and aerodynamic when needed or high for shade and a windbreak on a cloudless day.
My one experience tarp camping in gail force winds above treeline camping required 50+ lb of rocks on each tie and even then some of the rocks didn't hold well.
Be prepared to really pile them on.
We didn't have to camp above treeline, but the trees in the area below were mostly dead from fire and disease. We didn't feel comfortable being surrounded by dead trees in gail force winds.
The boy scout troop over on the next ridge had lots of tent poles break that night.Jun 23, 2010 at 7:10 am #1622649
Tim CheekBPL Member
I suspect Will Rietveld has more experience in a tarp in the Weminuche than most on this board. I'd send him an email.
I've never had a problem staking above timberline in the Weminuche. And, as said, when you are on rocks, you used the rocks to hold your guylines.
You must be logged in to reply to this topic.


text:
Repower Guide
Engine Designs
Electrical System
Fuel & Exhaust
Other Considerations
Line Drawings
Ring... Ring.....
TEW: Hello, this is engine sales, how can we help you?
Caller: The engine on my <description> just died and...
Ring... Ring...
Caller: I'm looking for a new engine for my...
How To Guide: Repowering With A New Engine
Here at Tulsa Engine Warehouse, a large percentage of the phone calls we receive, begin with some variation of the sample conversations shown above. ...people just like yourself looking for assistance in selecting a new engine.
Although we appreciate each and every phone inquiry, we realize that due to the nature of the internet, someone is always out there looking for help so we've put this guide together covering the fundamentals for selecting a replacement engine.
To get started, the first and most important task is to compare the specifications and/or features from your existing engine as a point of reference. To help with that, we've prepared a chart in Adobe PDF format that you can print and record your info for a handy reference.
Engine Comparison Chart
Depending on your computer setup, you may choose to open the chart directly in a browser window or you may also "right-click" and save a copy to your local drive. For those of you who need the free Adobe Reader, just click the image above to visit the download site.
Overview: We will be working our way through six sections as shown in the side navigation bar to the left of this page, where we will to provide as much detail as possible to help you in making a selection. Of course, you are also always welcome to contact us using our toll free number if you need further assistance. 800-501-8061
Well, it's about time that we get started --->
Engine Identification
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text:
Investigating if Interferon-Beta Can be Used in Patients With MS After They Have Developed Neutralizing Antibodies (RECOVER)
- Full Text View
- Tabular View
- No Study Results Posted
- Disclaimer
- How to Read a Study Record
Relapsing-Remitting Multiple Sclerosis
Drug: Interferon-beta-1a
Drug: methylprednisolone
Phase 4
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|A Multicentre, Open Label, Non-Comparative Trial Investigating the Recovering of INF-Beta Efficacy in Breakthrough Relapsing-Remitting Multiple Sclerosis Patients With Neutralizing Interferon-Beta Antibodies
- Reduction in the proportion of patients being neutralizing antibody (NAb) positive (titre>20) [ Time Frame: Month -1 and after 3, 6, 9, 12, and 15 months ]
- Change in MxA protein values [ Time Frame: Month -1 and after 3, 6, 9, 12, and 15 months ]
- Change in binding antibody (Bab) tires [ Time Frame: Month -1 and after 3, 6, 9, 12, and 15 months ]
- Proportion of patients with NAb positive titre <5 [ Time Frame: Month -1 and after 3, 6, 9, 12, and 15 months ]
- Change in annualised relapse rate [ Time Frame: at 3, 6, 9, 12, and 15 months ]
- The number of relapse-free patients [ Time Frame: at 3, 6, 9, 12, and 15 months ]
|Study Start Date:
|March 2003
|Study Completion Date:
|August 2006
|Primary Completion Date:
|August 2006 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: 1
Drug: Interferon-beta-1a
dosage and frequency as per label
Other Name: AvonexDrug: methylprednisolone
dosage and frequency as per Biogen Idec protocol
Detailed Description:
This is a multi-center, open Label, non-comparative Phase IV trial. Eligible Patients will receive treatment with Interferon-beta-1a (AVONEX) 30mcg I.M. once weekly for up to 12 months.
In the wash-out period prior to commencing treatment with AVONEX, patients will receive treatment with intermittent Methylprednisolone 500 mg PO Daily for three consecutive days at monthly intervals.
The patients will be examined clinically and laboratory tests will be performed at screening (month -1) and after 3, 9, and 15 months.
Neutralizing antibody(NAb)titres and Binding antibody(BAb)titres as well as MxA protein levels will be evaluated at screening/baseline (month -1/0) and after 3, 6, 9, 12, and 15 months.
|Ages Eligible for Study:
|18 Years to 55 Years (Adult)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Relapsing remitting Multiple Sclerosis according to Poser criteria (CDMS or LDMS) or Multiple Sclerosis according to McDonald criteria
- Disability equivalent to EDSS of 6.0 or less
- Clinical activity defined as at least one relapse rate within the last 12 months
- NAb titre >20 (measured at least 48 hours after last interferon-beta injection
- has been treated with subcutaneously administered interferon-beta-1b or interferon-beta-1a (Rebif) for at least 24 hours before enrollment
Exclusion Criteria:
- Any condition that might give rise to similar symptoms as MS
- Immunomodulatory therapy other than interferon-beta-1a or interferon-beta-1b or any immunosuppressive treatment six months prior to inclusion into the trial
- Treatment with glucocorticoids or ACTH less than one month prior to inclusion into the trial
- History of major depression
- Alcohol or drug dependency
- Cardiac insufficiency, cardiomyopathy, significant cardiac dysrhythmia, unstable or advanced ischemic heart disease (NYHA III or IV)
- hypertension (BP > 180/110 mmHg)
- Renal insufficiency defined as serum creatinine > 1.5 times the upper normal reference limit
- Any systemic disease that can influence the patient's safety and compliance, or the evaluation of the disability
- Gastro-intestinal ulcers, gastritis, or dyspepsia
- Women who are pregnant, breast-feeding or have the possibility for pregnancy during the trial. To avoid pregnancy, women have to be postmenopausal, surgical sterile, sexually inactive or practice reliable contraceptives
Please refer to this study by its ClinicalTrials.gov identifier: NCT00492466
|Coordinating Research Site
|Turku, Finland
|Principal Investigator:
|Biogen-Idec Investigator
|Responsible Party:
|biogen Idec MD, Biogen Idec
|ClinicalTrials.gov Identifier:
|NCT00492466 History of Changes
|Other Study ID Numbers:
|Study First Received:
|June 25, 2007
|Last Updated:
|January 28, 2008
Keywords provided by Biogen:
Multiple Sclerosis
Neutralizing antibody
Binding antibody
MxA protein
Additional relevant MeSH terms:
Multiple Sclerosis
Multiple Sclerosis, Relapsing-Remitting
Pathologic Processes
Demyelinating Autoimmune Diseases, CNS
Autoimmune Diseases of the Nervous System
Nervous System Diseases
Demyelinating Diseases
Autoimmune Diseases
Immune System Diseases
Methylprednisolone Hemisuccinate
Interferon beta-1a
Prednisolone acetate
Methylprednisolone acetate
Prednisolone hemisuccinate
Prednisolone phosphate
Antineoplastic Agents
Antiviral Agents
Anti-Infective Agents
Immunologic Factors
Physiological Effects of Drugs
Anti-Inflammatory Agents
Autonomic Agents
ClinicalTrials.gov processed this record on May 25, 2017


text:
Brewer at the Legislature: No on TIF expansion
Groene at the Legislature: Addressing TIF expansion
More opinion
Fischers bill addresses on-farm fuel storage
Farm Bureau: Top 10 EPA regulations to modify or repeal
More Ag News
The North Platte Community College Lady Knights volleyball team announced the signing of Taylor King and Abby Kurtzer of Fleming, Colo.
King and Kurtzer led the Fleming Wildcats to a 20-9 record and a semifinal appearance in the 2012 Colorado IA State Volleyball Championships.
King will play an outside hitter for the Lady Knights. King had 337 kills and 419 digs for the Wildcats.
"When I went up for the visit I was pretty set on going somewhere else. But I just fell in love," said King. "It was so much closer and the girls were very welcoming and the coach was unbelievably welcoming and I just knew it was the place for me."
Kurtzer will play several positions for the Lady Knights. Kurtzer had 270 kills and 209 digs for the Wildcats.
"It was a really hard decision for me, but I really felt like it was a better fit for me," Kurtzer said. "I liked the setting with the team and with the classroom, as well."
We are very excited to add two great competitors and winners that come from a great program and a winning program, said head coach Sally Thalken. We are excited to welcome them to North Platte Community College and our volleyball program.
Flatrock Publishing, Inc.
1300 E 4th St., Suite F
North Platte, NE 69101


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Was it good at least? Should have taken her to mcdonalds as soon as she acted weird
"you dont need to put your P in a V right now!!"
"Youre right...what i need is to B my L all over someone's Ts!!"
"Peter, that's gross!!!"
Oderint Dum Metuant
It's too bad, I'm too good....


text: My harvest was 22 pints from 2 hives this year. I have 10 hives total in my yard, 2 being Nucs. The only honey I was able to harvest this year was from my two newest hives which were from 3lb packages installed on 3/26. Why did my established hives not produce anything? Is there any action that I should take?