text:
International Nuclear Information System (INIS)
A new isotope of berkelium, 242Bk, was produced with a cross section of approx. 10 μb in reactions of boron on uranium and nitrogen on thorium. It decays by electron capture with a half-life of 7 +- 1.3 minutes. The branching ratio for this isotope for alpha decay is less than 1% and that for spontaneous fission is less than 0.03%. 2 figures, 2 tables
Characterization of berkelium(III) dipicolinate and borate compounds in solution and the solid state.
Silver, Mark A; Cary, Samantha K; Johnson, Jason A; Baumbach, Ryan E; Arico, Alexandra A; Luckey, Morgan; Urban, Matthew; Wang, Jamie C; Polinski, Matthew J; Chemey, Alexander; Liu, Guokui; Chen, Kuan-Wen; Van Cleve, Shelley M; Marsh, Matthew L; Eaton, Teresa M; van de Burgt, Lambertus J; Gray, Ashley L; Hobart, David E; Hanson, Kenneth; Maron, Laurent; Gendron, Frédéric; Autschbach, Jochen; Speldrich, Manfred; Kögerler, Paul; Yang, Ping; Braley, Jenifer; Albrecht-Schmitt, Thomas E
Berkelium is positioned at a crucial location in the actinide series between the inherently stable half-filled 5f(7) configuration of curium and the abrupt transition in chemical behavior created by the onset of a metastable divalent state that starts at californium. However, the mere 320-day half-life of berkelium's only available isotope, (249)Bk, has hindered in-depth studies of the element's coordination chemistry. Herein, we report the synthesis and detailed solid-state and solution-phase characterization of a berkelium coordination complex, Bk(III)tris(dipicolinate), as well as a chemically distinct Bk(III) borate material for comparison. We demonstrate that berkelium's complexation is analogous to that of californium. However, from a range of spectroscopic techniques and quantum mechanical calculations, it is clear that spin-orbit coupling contributes significantly to berkelium's multiconfigurational ground state. PMID:27563098
28 CFR 25.3 - System information.
... 28 Judicial Administration 1 2010-07-01 2010-07-01 false System information. 25.3 Section 25.3 Judicial Administration DEPARTMENT OF JUSTICE DEPARTMENT OF JUSTICE INFORMATION SYSTEMS The National Instant Criminal Background Check System § 25.3 System information. (a) There is established at the FBI...
32 CFR 253.5 - Responsibilities.
... 32 National Defense 2 2010-07-01 2010-07-01 false Responsibilities. 253.5 Section 253.5 National Defense Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS... MILITARY SERVICES § 253.5 Responsibilities. (a) The Deputy Under Secretary of Defense for Policy,...
33 CFR 117.253 - Anacostia River.
... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Anacostia River. 117.253 Section 117.253 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements District of Columbia § 117.253 Anacostia River....
36 CFR 25.3 - Supervision; suspensions.
... 36 Parks, Forests, and Public Property 1 2010-07-01 2010-07-01 false Supervision; suspensions. 25.3 Section 25.3 Parks, Forests, and Public Property NATIONAL PARK SERVICE, DEPARTMENT OF THE INTERIOR NATIONAL MILITARY PARKS; LICENSED GUIDE SERVICE REGULATIONS § 25.3 Supervision; suspensions. (a) The...
... 7 Agriculture 4 2010-01-01 2010-01-01 false Administration. 253.4 Section 253.4 Agriculture... GENERAL REGULATIONS AND POLICIES-FOOD DISTRIBUTION ADMINISTRATION OF THE FOOD DISTRIBUTION PROGRAM FOR HOUSEHOLDS ON INDIAN RESERVATIONS § 253.4 Administration. (a) Federal administration. Within the...
... 7 Agriculture 12 2010-01-01 2010-01-01 false Definitions. 1901.253 Section 1901.253 Agriculture... § 1901.253 Definitions. (a) Undertaking means any new or continuing projects or program activities..., and culture maintained by the Secretary of the Interior under the authority of section 2(b) of...
Notes from Sidney Coleman's Physics 253a
Coleman, Sidney
These notes were taken by Brian Hill during Sidney Coleman's lectures on Quantum Field Theory (Physics 253), given at Harvard University in Fall semester of the 1986-1987 academic year. They were recently typeset, edited and reorganized by Bryan Chen and Yuan-Sen Ting. Although most of topics in the second part of the course (Physics 253b) were assembled and published in Coleman's book "Aspects of Symmetry", these notes remain the principal source for the Physics 253a materials. [See also http://www.physics.harvard.edu/about/Phys253.html for a video version of the course given in 1975-1976.
50 CFR 253.22 - State projects.
... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false State projects. 253.22 Section 253.22... State projects. (a) General—(1) Designation of state agency. The Governor of each state shall notify the... participation under the Act, to sign project documents, and to receive payments. (2) States that choose...
... 7 Agriculture 4 2010-01-01 2010-01-01 false Definitions. 253.2 Section 253.2 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... commodities on all or part of an Indian reservation. (j) Urban place means a town or city with a population...
40 CFR 264.253 - Response actions.
....253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES (CONTINUED) STANDARDS FOR OWNERS AND OPERATORS OF HAZARDOUS WASTE TREATMENT, STORAGE, AND DISPOSAL FACILITIES Waste Piles § 264.253 Response actions. (a) The owner or operator of waste pile units subject to § 264.251...
24 CFR 220.253 - Substitute mortgagors.
... Contract Rights and Obligations-Homes § 220.253 Substitute mortgagors. (a) Selling mortgagor. The mortgagee... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Substitute mortgagors. 220.253... the Commissioner's approval of a substitute mortgagor, as provided by this section. (b)...
40 CFR 761.253 - Chemical analysis.
... 40 Protection of Environment 30 2010-07-01 2010-07-01 false Chemical analysis. 761.253 Section 761.253 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) TOXIC SUBSTANCES CONTROL ACT... analysis. (a) Extract PCBs from the standard wipe sample collection medium and clean-up the extracted...
Oxidation-reduction properties of americium, curium, berkelium, californium, einsteinium and fermium, and thermodynamic consequences for the 5f series
International Nuclear Information System (INIS)
The amalgamation of 5f elements from Am to Fm has been studied by using 241Am, 244Cm, 249Bk, 249Cf, 252Cf, 253Es, 254Es, 252Fm and 255Fm with two electrochemical methods, radiocoulometry and radiopolarography, perfectly adapted to investigate extremely diluted solutions when the concentration of electroactive species is as low as 10-16M. The theory of radiocoulometry has been developed in the general cases of reversible and irreversible electrode process. It has been used to interpret the experimental data on the kinetic curves of amalgamation, and to estimate the standard rate constant of the electrode process in complexing medium (citric). On the other hand the radiopolarographic method has been applied to study the mechanism of reduction at the dropping mercury electrode of cations M3+ in aqueous medium to the metal M with formation of amalgam. The results are exploited into two directions: 1- Acquisition of some data concerning the oxidation-reduction properties of elements from Am to Fm. Therefore the standard electrode E0 [M(III-0)] potentials for Bk, Cf and Es, and the standard electrode E0 [M(II-0)] potential for Fm are estimated and the relative stability of each oxidation state (from II to VII) of 5f elements is discussed; 2- Acquisition of unknown thermodynamic data on transcalifornium elements. Correlations between 4f and 5f elements are precised and some divergences appear for the second half of 4f and 5f series (i.e. for 65<=Z<=71 and 97<=Z<=103)
Lifescience Database Archive (English)
Full Text Available CL253Contig1 644 8 Adiantum capillus-veneris contig: CL253contig1 sequence. Link to clone list Show CL2...53Contig1 Contig ID CL253Contig1 Length 644 Number of clones 8 Definition Adiantum capillus-veneris contig: CL2
Isomeric states in {sup 253}No
Energy Technology Data Exchange (ETDEWEB)
Lopez-Martens, A.; Hauschild, K.; Briancon, C.; Korichi, A. [CSNSM, IN2P3-CNRS, UMR8609 (France); Yeremin, A.V.; Belozerov, A.V.; Chelnokov, M.L.; Chepigin, V.I.; Gorshkov, V.A.; Kabachenko, A.P.; Malyshev, O.N.; Oganessian, Yu. Ts.; Popeko, A.G.; Sagaidak, R.N.; Shutov, A.V.; Svirikhin, A.I. [FLNR, JINR, Dubna (Russian Federation); Dorvaux, O.; Curien, D.; Gall, B.; Khalfallah, F.; Rousseau, M.; Rowley, N.; Stuttge, L. [IPHC-DRS, ULP, IN2P3-CNRS, Strasbourg (France); Desesquelles, P. [CSNSM, IN2P3-CNRS (France); Universite Paris-Sud, F-91405 Orsay (France); Guttormsen, M.; Larsen, A.C.; Siem, S.; Syed, N.U.H. [Oslo University, Department of Physics, Oslo (Norway); Hanappe, F. [Universite Libre de Bruxelles, Bruxelles (Belgium); Minkova, A. [Faculty of Physics, University of Sofia (Bulgaria); INRNE, BAS, Sofia (Bulgaria); Sharo, S. [Comenius University, Department of Physics, Bratislava (Slovakia)
Isomeric states in {sup 253}No have been investigated by conversion electron and {gamma}-ray spectroscopy with the GABRIELA detection system. The 31 {mu}s isomer reported more than 30 years ago is found to decay to the ground state of {sup 253}No by the emission of a 167keV M2 transition. The spin and parity of this low-lying isomeric state are established to be 5/2{sup +}. The presence of another longer-lived isomeric state is also discussed. (orig.)
... Department of Defense (Continued) OFFICE OF THE SECRETARY OF DEFENSE (CONTINUED) MISCELLANEOUS ASSIGNMENT OF... SERVICES § 253.3 Definition. Employee. Any full-time, salaried individual serving with or employed by the Red Cross or the USO who is subject to assignment for overseas duty with the Military Services....
37 CFR 253.9 - Unknown copyright owners.
... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Unknown copyright owners. 253.9 Section 253.9 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT... NONCOMMERCIAL EDUCATIONAL BROADCASTING § 253.9 Unknown copyright owners. If PBS and its stations, NPR and...
37 CFR 253.2 - Definition of public broadcasting entity.
... CONNECTION WITH NONCOMMERCIAL EDUCATIONAL BROADCASTING § 253.2 Definition of public broadcasting entity. As... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Definition of public broadcasting entity. 253.2 Section 253.2 Patents, Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY...
24 CFR 983.253 - Leasing of contract units.
... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Leasing of contract units. 983.253 Section 983.253 Housing and Urban Development Regulations Relating to Housing and Urban Development... DEVELOPMENT PROJECT-BASED VOUCHER (PBV) PROGRAM Occupancy § 983.253 Leasing of contract units. (a)...
7 CFR 253.3 - Availability of commodities.
... 7 Agriculture 4 2010-01-01 2010-01-01 false Availability of commodities. 253.3 Section 253.3... FOR HOUSEHOLDS ON INDIAN RESERVATIONS § 253.3 Availability of commodities. (a) Conditions for... commodities to households under the authority of any law, except that distribution may be made (1) on...
Powering the superwind in NGC 253
Watson, Alan; Gallagher, Jay; Merrill, Michael; Keppel, Jean; Phillips, Mark
NGC 253 is a prototypical moderate nuclear starburst galaxy. It is a barred SBc spiral galaxy at a distance of approximately 3 Mpc and can be studied on scales down to 15 pc in the optical and near IR. It is a bright IRAS source with a flux of 1000 Jy at 60 microns and a FIR luminosity of 3 x 10(exp 10) solar luminosity. It has a strong Br(gamma) emission line, a signature of ongoing massive star formation and deep CO absorption bands, which are indicative of the dominance of red supergiants in the near IR. It contains a population of compact radio sources, similar to those seen in M82. Optical spectra show that the nucleus is heavily reddened, with a Balmer decrement of approximately 30. NGC 253 possesses a 'superwind,' seen both in x-ray emission and in optical line emission. Nuclear ejection was first suggested to explain the kinematics of the nuclear region. We have obtained J, H, and K images of the entire galaxy at 1.3 arcsec/pixel (18 pc/pixel) using the superconducting quantum interference device (SQUID) on the KPNO 1.3 m. We have constructed a mosaic of 180 s exposures which traces the galaxy over much of its optical extent. The data were shifted, rotated, magnified, and calibrated following normal practice.
The Resolved Stellar Halo of NGC 253
Bailin, Jeremy; Chappell, Samantha N; Radburn-Smith, David J; de Jong, Roelof S
We have obtained Magellan/IMACS and HST/ACS imaging data that resolve red giant branch stars in the stellar halo of the starburst galaxy NGC 253. The HST data cover a small area, and allow us to accurately interpret the ground-based data, which cover 30% of the halo to a distance of 30 kpc, allowing us to make detailed quantitative measurements of the global properties and structure of a stellar halo outside of the Local Group. The geometry of the halo is significantly flattened in the same sense as the disk, with a projected axis ratio of b/a ~ 0.35 +/- 0.1. The total stellar mass of the halo is estimated to be M_halo ~ 2.5 +/- 1.5 x 10^9 M_sun, or 6% of the total stellar mass of the galaxy, and has a projected radial dependence that follows a power law of index -2.8 +/- 0.6, corresponding to a three-dimensional power law index of ~ -4. The total luminosity and profile shape that we measure for NGC 253 are somewhat larger and steeper than the equivalent values for the Milky Way and M31, but are well within t...
Energy Technology Data Exchange (ETDEWEB)
Günthardt, G. I.; Camperi, J. A. [Observatorio Astronómico, Universidad Nacional de Córdoba (Argentina); Agüero, M. P. [Observatorio Astronómico, Universidad Nacional de Córdoba, and CONICET (Argentina); Díaz, R. J.; Gomez, P. L.; Schirmer, M. [Gemini Observatory, AURA (United States); Bosch, G., E-mail: email@example.com, E-mail: firstname.lastname@example.com, E-mail: email@example.com, E-mail: firstname.lastname@example.com, E-mail: firstname.lastname@example.com, E-mail: firstname.lastname@example.com, E-mail: firstname.lastname@example.com [Instituto de Astrofísica de La Plata (CONICET-UNLP) (Argentina)
NGC 253 is the nearest spiral galaxy with a nuclear starburst that becomes the best candidate for studying the relationship between starburst and active galactic nucleus activity. However, this central region is veiled by large amounts of dust, and it has been so far unclear which is the true dynamical nucleus to the point that there is no strong evidence that the galaxy harbors a supermassive black hole co-evolving with the starburst as was supposed earlier. Near-infrared (NIR) spectroscopy, especially NIR emission line analysis, could be advantageous in shedding light on the true nucleus identity. Using Flamingos-2 at Gemini South we have taken deep K-band spectra along the major axis of the central structure and through the brightest infrared source. In this work, we present evidence showing that the brightest NIR and mid-infrared source in the central region, already known as radio source TH7 and so far considered just a large stellar supercluster, in fact presents various symptoms of a genuine galactic nucleus. Therefore, it should be considered a valid nucleus candidate. Mentioning some distinctive aspects, it is the most massive compact infrared object in the central region, located at 2.″0 of the symmetry center of the galactic bar, as measured in the K-band emission. Moreover, our data indicate that this object is surrounded by a large circumnuclear stellar disk and it is also located at the rotation center of the large molecular gas disk of NGC 253. Furthermore, a kinematic residual appears in the H{sub 2} rotation curve with a sinusoidal shape consistent with an outflow centered in the candidate nucleus position. The maximum outflow velocity is located about 14 pc from TH7, which is consistent with the radius of a shell detected around the nucleus candidate, observed at 18.3 μm (Qa) and 12.8 μm ([Ne ii]) with T-ReCS. Also, the Brγ emission line profile shows a pronounced blueshift and this emission line also has the highest equivalent width at this
14 CFR 23.253 - High speed characteristics.
... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false High speed characteristics. 23.253 Section... Requirements § 23.253 High speed characteristics. If a maximum operating speed VMO/MMO is established under § 23.1505(c), the following speed increase and recovery characteristics must be met: (a)...
42 CFR 403.253 - Calculation of benefits.
... calculate the amount of "benefits" in the case of community or pool rated individual or group policies... 42 Public Health 2 2010-10-01 2010-10-01 false Calculation of benefits. 403.253 Section 403.253 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES...
14 CFR 21.253 - Type certificates: application.
... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Type certificates: application. 21.253 Section 21.253 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION... amended type certificate, the manufacturer must submit to the Administrator— (1) An application for a...
17 CFR 256.253 - Other deferred credits.
... 17 Commodity and Securities Exchanges 3 2010-04-01 2010-04-01 false Other deferred credits. 256... HOLDING COMPANY ACT OF 1935 8. Deferred Credits § 256.253 Other deferred credits. This account shall include advance billings and receipts and other deferred credit items, not provided for...
14 CFR 25.253 - High-speed characteristics.
... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false High-speed characteristics. 25.253 Section...-speed characteristics. (a) Speed increase and recovery characteristics. The following speed increase and recovery characteristics must be met: (1) Operating conditions and characteristics likely to...
37 CFR 253.7 - Recording rights, rates and terms.
... 37 Patents, Trademarks, and Copyrights 1 2010-07-01 2010-07-01 false Recording rights, rates and... NONCOMMERCIAL EDUCATIONAL BROADCASTING § 253.7 Recording rights, rates and terms. (a) Scope. This section... include: (i) The title, composer and author to the extent such information is reasonably obtainable....
27 CFR 46.253 - Destruction of articles by a Presidentially-declared major disaster.
... a Presidentially-declared major disaster. 46.253 Section 46.253 Alcohol, Tobacco Products and....253 Destruction of articles by a Presidentially-declared major disaster. After the dealer has paid the..., or condemned because of a Presidentially-declared major disaster. Subpart C of this part...
ACA [CI] observations of the starburst galaxy NGC 253
Krips, M.; Martín, S.; Sakamoto, K.; Aalto, S.; Bisbas, T. G.; Bolatto, A. D.; Downes, D.; Eckart, A.; Feruglio, Ch.; García-Burillo, S.; Geach, J.; Greve, T. R.; König, S.; Matsushita, S.; Neri, R.; Offner, S.; Peck, A. B.; Viti, S.; Wagg, J.
Context. Carbon monoxide (CO) is widely used as a tracer of the molecular gas in almost all types of environments. However, several shortcomings of CO complicate usaging it as H2 tracer, such as its optical depth effects, the dependence of its abundance on metallicity, or its susceptibility to dissociation in highly irradiated regions. Neutral carbon emission has been proposed to overcome some of these shortcomings and hence to help revealing the limits of CO as a measure of the molecular gas. Aims: We aim to study the general characteristics of the spatially and spectrally resolved carbon line emission in a variety of extragalactic sources and evaluate its potential as complementary H2 tracer to CO. Methods: We used the Atacama Compact Array to map the [CI](3P1-3P0) line emission in the nearby starburst galaxy NGC 253 at unprecedented angular resolution (~3''). This is the first well-resolved interferometric [CI] map of an extragalactic source. Results: We have detected the [CI] line emission at high significance levels along the central disk of NGC 253 and its edges where expanding shells have previously been found in CO. Globally, the distribution of the [CI] line emission strongly resembles that of CO, confirming the results of previous Galactic surveys that [CI] traces the same molecular gas as CO. However, we also identify a significant increase of [CI] line emission with respect to CO in (some of) the outflow or shocked regions of NGC 253, namely the bipolar outflow emerging from the nucleus. A first-order estimate of the [CI] column densities indicates abundances of [CI] that are very similar to the abundance of CO in NGC 253. Interestingly, we find that the [CI] line is marginally optically thick within the disk. Conclusions: The enhancement of the [CI]/CO line ratios (~0.4-0.6) with respect to Galactic values (≤0.1), especially in the shocked regions of NGC 253, clearly indicates that mechanical perturbation such as shocks and the strong radiation
48 CFR 253.213-70 - Completion of DD Form 1155, Order for Supplies or Services.
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Completion of DD Form 1155... Forms 253.213-70 Completion of DD Form 1155, Order for Supplies or Services. Follow the procedures at PGI 253.213-70 for completion of DD Form 1155....
48 CFR 253.215-70 - DD Form 1547, Record of Weighted Guidelines Application.
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false DD Form 1547, Record of... Forms 253.215-70 DD Form 1547, Record of Weighted Guidelines Application. Follow the procedures at PGI 253.215-70 for completing DD Form 1547....
48 CFR 253.208-2 - DD Form 448-2, Acceptance of MIPR.
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false DD Form 448-2, Acceptance... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE CLAUSES AND FORMS FORMS Prescription of Forms 253.208-2 DD Form 448-2, Acceptance of MIPR. Follow the procedures at PGI 253.208-2 for use of DD Form 448-2....
Long-term effects of intratracheally instilled 253EsCl3 in rats
International Nuclear Information System (INIS)
ts administered 253EsCl3 by intratracheal instillation developed more bone tumors and fewer lung tumors than similar rats administered 239Pu(NO3)4. In explanation, it is suggested that 253Es may irradiatete bone surface cells more effectively while 239Pu may irradiate a greater total number of cells in the lung. (U.S.)
29 CFR 779.253 - What is included in computing the total annual inflow volume.
... volume. 779.253 Section 779.253 Labor Regulations Relating to Labor (Continued) WAGE AND HOUR DIVISION... computing the total annual inflow volume. The goods which the establishment purchases or receives for resale that move or have moved across State lines must "amount in total annual volume to $250,000 or more."...
Large family of compact radio sources in the starburst nucleus of NGC 253
International Nuclear Information System (INIS)
Deep VLA maps of NGC 253 show that it has at least 35 compact radio sources similar to those in the prototypical IR starburst galaxy M82. It is noted that NGC 253 is a twin of M82 in IR spectrum and luminosity as well as distance. Some of the sources in M82 which are rapidly expanding and fading are believed to be extremely young supernova remnants. Most of the sources detected in NGC 253 are unresolved or only marginally resolved, with typical diameters no greater than 2-5 pc. If they are young supernova remnants expanding at 12,000 km/s, the source ages are no more than 160-400 yr. This requires a supernova rate of about 1/0.1 yr. If the compact radio sources are indeed young supernova remnants, star formation must have ceased shortly after the progenitors of the current supernovae were produced. 12 references
Late effects of inhaled 253Es(NO3)3 in the rat
International Nuclear Information System (INIS)
The lungs of rats exposed to 253Es(NO3)3 aerosols sustained the greatest cumulative radiation dose, approximately 6-fold higher than the skeletal dose. Malignant lung tumors (incidence 8.5, 27.6%) were observed after a mean cumulative lung dose of 26 and 400 rad, respectively. Higher lung doses were associated with severe life shortening that precluded the expression of delayed effects. Osteosarcomas of the skeleton (incidence 6.9%) were found after a mean cumulative skeletal dose of 68 rad. Earlier studies, which showed a high incidence of bone tumors and relatively fewer lung tumors after intratracheal instillation of 253EsCl3, were not confirmed in this study with inhaled 253Es(NO3)3
G0.253+0.016: A Centrally Condensed, High-mass Protocluster
Rathborne, J. M.; Longmore, S. N.; Jackson, J. M.; Foster, J. B.; Contreras, Y.; Garay, G.; Testi, L.; Alves, J. F.; Bally, J.; Bastian, N.; Kruijssen, J. M. D.; Bressert, E.
Despite their importance as stellar nurseries and the building blocks of galaxies, very little is known about the formation of the highest mass clusters. The dense clump G0.253+0.016 represents an example of a clump that may form an Arches-like, high-mass cluster. Here we present molecular line maps toward G0.253+0.016 taken as part of the MALT90 molecular line survey, complemented with APEX observations. Combined, these data reveal the global physical properties and kinematics of G0.253+0.016. Recent Herschel data show that while the dust temperature is low (~19 K) toward its center, the dust temperature on the exterior is higher (~27 K) due to external heating. Our new molecular line data reveal that, overall, the morphology of dense gas detected toward G0.253+0.016 matches its IR extinction and dust continuum emission very well. An anticorrelation between the dust and gas column densities toward its center indicates that the clump is centrally condensed with a cold, dense interior in which the molecular gas is chemically depleted. The velocity field shows a strong gradient along the clump's major axis, with the blueshifted side at a higher Galactic longitude. The optically thick gas tracers are systematically redshifted with respect to the optically thin and hot gas tracers, indicating radial motions. The gas kinematics and line ratios support the recently proposed scenario in which G0.253+0.016 results from a tidal compression during a recent pericenter passage near Sgr A*. Because G0.253+0.016 represents an excellent example of a clump that may form a high-mass cluster, its detailed study should reveal a wealth of knowledge about the early stages of cluster formation.
High energy (gamma)-ray emission from the starburst nucleus of NGC 253
Energy Technology Data Exchange (ETDEWEB)
Domingo-Santamaria, E; Torres, D F
The high density medium that characterizes the central regions of starburst galaxies and its power to accelerate particles up to relativistic energies make these objects good candidates as {gamma}-rays sources. In this paper, a self-consistent model of the multifrequency emission of the starburst galaxy NGC 253, from radio to gamma-rays, is presented. The model is in agreement with all current measurements and provides predictions for the high energy behavior of the NGC 253 central region. Prospects for observations with the HESS array and GLAST satellite are especially discussed.
Mid-infrared [NeII] line emission from the nucleus of NGC 253
Böker, T; Storey, J W V
We report on mid-infrared (MIR) continuum and line emission mapping of the nucleus of NGC 253. The data, with a resolution of 1\\as.4, reveal a double-peaked arc-like [NeII] emission region. Comparison with published data shows that the [NeII] arc is centered on the nucleus of the galaxy. The brightest [NeII] source coincides with the infrared continuum peak. The interpretation of these results is complicated by the edge-on orientation of NGC 253, but a self-consistent explanation is starformation triggered by dynamical resonances in a barred potential.
Analysis of 253 Cases with Urtarcia%荨麻疹253例病因探讨
Institute of Scientific and Technical Information of China (English)
目的:通过查找血清特异性IgE,总结荨麻疹可能引起的病因。方法抽取患者血清,采用全自动免疫印迹仪加用吸入性及食入性过敏源特异性IgE抗体检测试剂盒(欧蒙印迹法)来测定患者血清中特异性IgE的浓度,判断荨麻疹的病因。结果吸入性特异性IgE检出率依次为艾蒿70.3%,蟑螂35.6%,屋尘13.4%,葎草11.1%,尘螨组合(屋尘螨/粉尘螨)11.1%,树组合(柳树/杨树/榆树)9.5%,点青霉/分支孢霉/烟曲霉/交链孢霉9.5%,普通豚草8.3%,猫毛7.1%,狗上皮2.7%;食入性特异性IgE检出率依次为海洋鱼组合(鳕鱼/龙虾/扇贝)63.2%,蟹25.6%,花生28.1%,淡水组合(鲑鱼/鲈鱼/鲤鱼)14.2%,蛋清11.1%,牛奶11.1%,牛肉11.1%,羊肉11.1%,虾11.1%,黄豆8.3%。单种致敏原58例,占22.9%,多种致敏原(两种及两种以上)165例,占65.2%,未测出致敏原的30例,占11.8%。结论引起荨麻疹的病因复杂,吸入物和食入物皆有,且可能同时存在,吸入物以艾蒿为最多,食入物以海鲜类最多,且同一患者致敏原常为多种。%Objective This article is aiming to find out the possible causes of urticaria by analysing 253 patients'serum SIgE. Methods Serum and red cell were separated and serum were used to allergen screening test to find out the allergen by testing specific IgE concentration with food SIgE antibody and inhaled SIgE antibody test reagents. In inhaled group allergens are mugwort 70.3%, cockroach 35.6%, dust 13.4%, scandent hop11.1%, dust mite 11.1%, trees 9.5%, penicillin 9.5%, ragweed 8.3%, cat hair 7.1%, dog fur 2.7%..In ingested group, the positive rates of different allergens are shellfish 63.2%, crab 25.6%, peanuts 28.1%, freshwater fish 14.2%, egg white 11.1%, milk 11.1%, beef 11.1%, lamb 11.1%, shrimp 11.1%, soya beans 8.3%. 22.9%of patients only had one aller⁃gen which are 58 cases. 65.2%of patients had two or more allergens
30 CFR 253.14 - How do I determine the worst case oil-spill discharge volume?
... discharge volume that you determined under whichever of the following regulations applies: (1) 30 CFR Part... estimate for the first 24 hours. (2) 40 CFR Part 112—Oil Pollution Prevention; or (3) 49 CFR Part 194... discharge volume? 253.14 Section 253.14 Mineral Resources MINERALS MANAGEMENT SERVICE, DEPARTMENT OF...
The link between solenoidal turbulence and slow star formation in G0.253+0.016
Federrath, C; Longmore, S N; Kruijssen, J M D; Bally, J; Contreras, Y; Crocker, R M; Garay, G; Jackson, J M; Testi, L; Walsh, A J
Star formation in the Galactic disc is primarily controlled by gravity, turbulence, and magnetic fields. It is not clear that this also applies to star formation near the Galactic Centre. Here we determine the turbulence and star formation in the CMZ cloud G0.253+0.016. Using maps of 3mm dust emission and HNCO intensity-weighted velocity obtained with ALMA, we measure the volume-density variance $\\sigma_{\\rho/\\rho_0} = 1.3 \\pm 0.5$ and turbulent Mach number $\\mathcal{M} = 11 \\pm 3$. Combining these with turbulence simulations to constrain the plasma $\\beta = 0.34 \\pm 0.35$, we reconstruct the turbulence driving parameter $b = 0.22 \\pm 0.12$ in G0.253+0.016. This low value of $b$ indicates solenoidal (divergence-free) driving of the turbulence in G0.253+0.016. By contrast, typical clouds in the Milky Way disc and spiral arms have a significant compressive (curl-free) driving component ($b > 0.4$). We speculate that shear causes the solenoidal driving in G0.253+0.016 and show that this may reduce the star forma...
42 CFR 441.253 - Sterilization of a mentally competent individual aged 21 or older.
... 42 Public Health 4 2010-10-01 2010-10-01 false Sterilization of a mentally competent individual... LIMITS APPLICABLE TO SPECIFIC SERVICES Sterilizations § 441.253 Sterilization of a mentally competent individual aged 21 or older. FFP is available in expenditures for the sterilization of an individual only...
The world on a train: global narration in Geoff Ryman's 253
Directory of Open Access Journals (Sweden)
Berthold Schoene,
Full Text Available The focus of this essay is an exploration of Geoff Ryman's interactive novel 253, which was originally released online as 253, or Tube Theatre: A Novel for the Internet on London Underground in Seven Cars and a Crash and then, two years later in 1998, also as a 'print remix'. Examining Ryman's text as an example of contemporary global narration, Schoene explores the cosmopolitan techniques and structural devices employed in 253 not merely to envisage the individual's immersion in global community but to facilitate an enduring interactive experience of it. Aligning the hypertextuality of 253 with Jean-Luc Nancy's philosophy of community, Schoene argues that Ryman's use of hyperlinks does not destroy plot, but deconstructs it, reconceiving it as fluid and 'inoperative' instead of strictly telos-driven. With close reference to Ryman's 'The World on a Train', his BBC News tribute to the 52 victims of the 7/7 London terrorist attacks, the essay concludes by looking at the new cosmopolitical currency acquired by Ryman's novel – a currency it did not originally have in the mid-1990s.
29 CFR 25.3 - Requests for nomination of arbitrators: Filing, disputes, parties, time.
... 29 Labor 1 2010-07-01 2010-07-01 true Requests for nomination of arbitrators: Filing, disputes... ARBITRATORS UNDER SECTION 11 OF EXECUTIVE ORDER 10988 § 25.3 Requests for nomination of arbitrators: Filing... entertain on its merits a request by an employee organization for nomination of an arbitrator on a...
48 CFR 253.208-1 - DD Form 448, Military Interdepartmental Purchase Request.
... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false DD Form 448, Military... DD Form 448, Military Interdepartmental Purchase Request. Follow the procedures at PGI 253.208-1 for use of DD Form 448....
Ozone decomposition under the irradiation of 253.7 nm in the presence of methyl bromide
Institute of Scientific and Technical Information of China (English)
In this paper the mechanism and kinetic of ozone decomposition under the irradiation of 253.7 nm UV-light were studied.The quantum yield of the ozone depletion in the presence of methyl bromide is further determined and a reaction model is provided to explain the experimental fact.
Jiaxing Eastern Steel Cord Co., Ltd. Invested USD 253 Million for Expansion
Institute of Scientific and Technical Information of China (English)
Hao Tian
To develop the company, Jiaxing Eastern Cord Co., Ltd. determined to invest USD 253 million (amounting to RMB 1.593 billion yuan) to construct a new factory in Jiaxing Economic and Technological Development Zone with steel cord annual production capacity of 80 thousand tons and solar silicon wafer cutting wire annual production capacity of 20 thousand tons by off- site expansion.
G0.253+0.016: A centrally condensed, high-mass protocluster
Rathborne, J M; Jackson, J M; Foster, J B; Contreras, Y; Garay, G; Testi, L; Alves, J F; Bally, J; Bastian, N; Kruijssen, J M D; Bressert, E
Despite their importance as stellar nurseries and the building blocks of galaxies, very little is known about the formation of the highest mass clusters. The dense clump G0.253+0.016 represents an example of a clump that may form an Arches-like, high-mass cluster. Here we present molecular line maps toward G0.253+0.016 taken as part of the MALT90 molecular line survey, complemented with APEX observations. Combined, these data reveal the global physical properties and kinematics of G0.253+0.016. Recent Herschel data show that while the dust temperature is low (~19 K) toward its centre, the dust temperature on the exterior is higher (~27 K) due to external heating. Our new molecular line data reveal that, overall, the morphology of dense gas detected toward G0.253+0.016 matches very well its IR extinction and dust continuum emission. An anti-correlation between the dust and gas column densities toward its centre indicates that the clump is centrally condensed with a cold, dense interior in which the molecular g...
Refinement of the critical 2p25.3 deletion region
DEFF Research Database (Denmark)
De Rocker, Nina; Vergult, Sarah; Koolen, David;
PURPOSE: Submicroscopic deletions of chromosome band 2p25.3 are associated with intellectual disability and/or central obesity. Although MYT1L is believed to be a critical gene responsible for intellectual disability, so far no unequivocal data have confirmed this hypothesis. METHODS: In this stu...
Theoretical Explanation of the Cosmic Ray Perpendicular Diffusion Coefficient in the Nearby Starburst Galaxy NGC 253
Buffie, Kaitlynn; Heesen, Volker; Shalchi, Andreas
Diffusion coefficients are usually used to describe the propagation of Cosmic Rays through the Universe. Whereas such transport parameters can be obtained from experiments in the Solar System, it is difficult to determine diffusion coefficients in the Milky Way or in external galaxies. Recently a value for the perpendicular diffusion coefficient in the nearby starburst halaxy NGC 253 has been proposed. In the present paper we reproduce this value theoretically by using an advanced analytical ...
The St. Jude Medical Valve: Early Clinical Results in 253 Patients
Duncan, J. Michael; Cooley, Denton A.; Livesay, James J.; Ott, David A.; Reul, George J.; Walker, William E.; Frazier, O. Howard
The St. Jude Medical cardiac valve is a low-profile, bileaflet, central-flow prosthesis made entirely of pyrolytic carbon. A total of 261 St. Jude valves were implanted in 253 patients during a 25-month period. Perioperative mortality for the entire series was 9.1%, including patients undergoing reoperation for valve disease and those having associated cardiac procedures. There were four nonfatal thromboembolic episodes during the follow-up period, resulting in a risk of thromboembolism for a...
Nonthermal Emission in the Starburst Galaxies M 82 and NGC 253
Energy Technology Data Exchange (ETDEWEB)
Rephaeli, Yoel [School of Physics and Astronomy, Tel Aviv University, Tel Aviv, 69978 (Israel); Center for Astrophysics and Space Sciences, University of California, San Diego, La Jolla, CA 92093 (United States); Persic, Massimo [INAF/Osservatorio Astronomico di Trieste, via G.B.Tiepolo 11, I-34143 Trieste (Italy); INFN-Trieste, via A.Valerio 2, I-34127 Trieste (Italy)
Detection of high-energy γ-ray emission from the nearby starburst galaxies M 82 and NGC 253 establishes, for the first time, a direct link between leptonic and hadronic processes in an extragalactic non-AGN environment. We review the most relevant aspects of these processes and contrast theoretical predictions with available radio and γ-ray measurements in order to determine the particle spectral properties and energy densities in these galaxies.
Hydrogen fluoride toward luminous nearby galaxies: NGC 253 and NGC 4945
Energy Technology Data Exchange (ETDEWEB)
Monje, R. R.; Lis, D. C.; Phillips, T. G. [California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125-4700 (United States); Lord, S. [Infrared Processing and Analysis Center, California Institute of Technology, MS 100-22, Pasadena, CA 91125 (United States); Falgarone, E. [LERMA/LRA, Ecole Normale Supérieure and Observatoire de Paris, 24 rue Lhomond, F-75005 Paris (France); Neufeld, D. A. [Department of Physics and Astronomy, Johns Hopkins University, 3400 North Charles Street, Baltimore, MD 21218 (United States); Güsten, R., E-mail: email@example.com [Max-Planck Institut für Radioastronomie, Auf dem Hügel 69, D-53121 Bonn (Germany)
We present the detection of hydrogen fluoride (HF) in two luminous nearby galaxies, NGC 253 and NGC 4945 using the Heterodyne Instrument for the Far-Infrared on board the Herschel Space Observatory. The HF line toward NGC 253 has a P-Cygni profile, while an asymmetric absorption profile is seen toward NGC 4945. The P-Cygni profile in NGC 253 suggests an outflow of molecular gas with a mass of M(H{sub 2}){sub out} ∼ 1 × 10{sup 7} M {sub ☉} and an outflow rate as large as M-dot ∼6.4 M {sub ☉} yr{sup –1}. In the case of NGC 4945, the axisymmetric velocity components in the HF line profile are compatible with the interpretation of a fast-rotating nuclear ring surrounding the nucleus and the presence of inflowing gas. The gas falls into the nucleus with an inflow rate of ≤1.2 M {sub ☉} yr{sup –1}, inside an inner radius of ≤200 pc. The gas accretion rate to the central active galactic nucleus is much smaller, suggesting that the inflow may be triggering a nuclear starburst. From these results, the HF J = 1-0 line is seen to provide an important probe of the kinematics of absorbing material along the sight-line to nearby galaxies with bright dust continuum and a promising new tracer of molecular gas in high-redshift galaxies.
Hydrogen Fluoride toward Luminous Nearby Galaxies: NGC 253 and NGC 4945
Monje, R R; Falgarone, E; Lis, D C; Neufeld, D A; Phillips, T G; Güsten, R
We present the detection of hydrogen fluoride, HF, in two luminous nearby galaxies NGC 253 and NGC 4945 using the Heterodyne Instrument for the Far-Infrared (HIFI) on board the Herschel Space Observatory. The HF line toward NGC 253 has a P-Cygni profile, while an asymmetric absorption profile is seen toward NGC 4945. The P-Cygni profile in NGC 253 suggests an outflow of molecular gas with a mass of M(H$_2$)$_{out}$ $\\sim$ 1 $\\times$ 10$^7$ M$_\\odot$ and an outflow rate as large as \\.{M} $\\sim$ 6.4 M$_\\odot$ yr$^{-1}$. In the case of NGC 4945, the axisymmetric velocity components in the HF line profile is compatible with the interpretation of a fast-rotating nuclear ring surrounding the nucleus and the presence of inflowing gas. The gas falls into the nucleus with an inflow rate of $\\le$ 1.2 M$_\\odot$ yr$^{-1}$, inside a inner radius of $\\le$ 200 pc. The gas accretion rate to the central AGN is much smaller, suggesting that the inflow can be triggering a nuclear starburst. From these results, the HF $J = 1-0$ ...
Satellite accretion in action: a tidally disrupting dwarf spheroidal around the nearby spiral galaxy NGC 253
Romanowsky, Aaron J; Martin, Nicolas F; Morales, Gustavo; Jennings, Zachary G; GaBany, R Jay; Brodie, Jean P; Grebel, Eva K; Schedler, Johannes; Sidonio, Michael
We report the discovery of NGC 253-dw2, a dwarf spheroidal (dSph) galaxy candidate undergoing tidal disruption around a nearby spiral galaxy, NGC 253 in the Sculptor group: the first such event identified beyond the Local Group. The dwarf was found using small-aperture amateur telescopes, and followed up with Suprime-Cam on the 8 m Subaru Telescope in order to resolve its brightest stars. Using g- and R_c-band photometry, we detect a red giant branch consistent with an old, metal-poor stellar population at a distance of ~ 3.5 Mpc. From the distribution of likely member stars, we infer a highly elongated shape with a semi-major axis half-light radius of (2 +/- 0.4) kpc. Star counts also yield a luminosity estimate of ~ 2x10^6 L_Sun,V (M_V ~ -10.7). The morphological properties of NGC 253-dw2 mark it as distinct from normal dSphs and imply ongoing disruption at a projected distance of ~ 50 kpc from the main galaxy. Our observations support the hierarchical paradigm wherein massive galaxies continously accrete l...
Energy Technology Data Exchange (ETDEWEB)
Sand, D. J.; Crnojević, D. [Physics Department, Texas Tech University, Box 41051, Lubbock, TX 79409-1051 (United States); Strader, J. [Department of Physics and Astronomy, Michigan State University, East Lansing, MI 48824 (United States); Toloba, E.; Guhathakurta, P. [UCO/Lick Observatory, University of California, Santa Cruz, 1156 High Street, Santa Cruz, CA 95064 (United States); Simon, J. D. [Observatories of the Carnegie Institution for Science, 813 Santa Barbara Street, Pasadena, CA 91101 (United States); Caldwell, N.; McLeod, B. [Harvard-Smithsonian Center for Astrophysics, Cambridge, MA 02138 (United States); Seth, A. C., E-mail: email@example.com [Department of Physics and Astronomy, University of Utah, Salt Lake City, UT 84112 (United States)
We report the discovery of a new faint dwarf galaxy, which we dub Scl-MM-Dw1, at a projected distance of ∼65 kpc from the spiral galaxy NGC 253. The discovery results from the Panoramic Imaging Survey of Centaurus and Sculptor (PISCeS), a program with the Magellan/Megacam imager to study faint substructure in resolved stellar light around massive galaxies outside of the Local Group. We measure a tip of the red giant branch distance to Scl-MM-Dw1 of D = 3.9 ± 0.5 Mpc, consistent with that of NGC 253, making their association likely. The new dwarf's stellar population is complex, with an old, metal-poor red giant branch (≳10 Gyr, [Fe/H] ∼ –2), and an asymptotic giant branch with an age of ∼500 Myr. Scl-MM-Dw1 has a half-light radius of r{sub h} = 340 ± 50 pc and an absolute magnitude of M{sub V} = –10.3 ± 0.6 mag, comparable to the Milky Way's satellites at the same luminosity. Once complete, our imaging survey of NGC 253 and other nearby massive galaxies will provide a census of faint substructure in halos beyond the Local Group, both to put our own environment into context and to confront models of hierarchical structure formation.
Rotational properties of $^{252, 253, 254}$No. Influence of pairing correlations
Duguet, T.; Bonche, P.; Heenen, P. -H.
Rotational bands of $^{252, 253, 254}$No and the fission barriers of $^{254}$No at spin 0$\\hbar$ and 20$\\hbar$ are calculated with the Hartree-Fock-Bogolyubov theory and the Lipkin-Nogami approximate particle number projection. The SLy4 Skyrme force is used in the particle-hole channel. A zero-range force with and without density-dependence is used in the particle-particle channel. The experimental ground state deformation (${\\cal{Q}}_{20}$ = 32.8 b) is reproduced as well as the increase of t...
Dark Filaments in the Galaxy NGC 253 - a Boiling Galactic Disk -
Sofue, Yoshiaki; Wakamatsu, Ken-ichi; Malin, David F.
We study the morphology of dark lanes and filaments in the dust-rich galaxy NGC 253 using an unsharp-masked $B$-band optical photograph. Dust features are classified as `arcs', which have heights and scale radius of about 100 to 300 pc, connecting two or more dark clouds, and `loops' and `bubbles', which are developed forms of arcs, expanding into the disk-halo interface. These have diameters of a few hundred pc to $\\sim 1$ kpc. Among the bubbles, we notice a peculiar round-shaped bubble abov...
Do the compact radio sources in NGC 253 and M82 fade over time?
Ulvestad, James S.; Antonucci, Robert R. J.
The nearby starburst galaxy NGC 253 has been observed at a third epoch at 6 cm, and a second epoch at 3.6 cm, using the highest resolution configuration of the Very Large Array (VLA). Over a total time span of 4 yr between 1987 and 1991, no new compact radio sources have appeared. The flux density limit ranges from 3 mJy (3 times the power of Cas A) for most of the main body of the source to approximately 0.3 mJy off the diffuse source surrounding the nucleus. Furthermore, there is no evidence for significant source fading over 4 yr, in contrast to the result reported by Kronberg & Sramek (1985) for M82. More recent data suggest that, except for the strongest source in that galaxy, the compact radio sources in M82 may not be fading after all. If this suggestion proves correct, supernova rates of 0.2-0.3/yr in M82, estimated based on the assumed source fading, are incorrect. More accurate limits on source fading indicate that the current rate of production of radio supernovae in M82 is no greater than 0.1/yr, while that in NGC 253 is no greater than 0.25/yr.
Cosmic-ray induced gamma-ray emission from the starburst galaxy NGC 253
Energy Technology Data Exchange (ETDEWEB)
Wang, Xilu; Fields, Brian D. [Department of Astronomy, MC-221, 1002 W. Green Street, University of Illinois at Urbana-Champaign, Urbana, IL 61801 (United States)
Cosmic rays in galaxies interact with the interstellar medium and give us a direct view of nuclear and particle interactions in the cosmos. For example, cosmic-ray proton interactions with interstellar hydrogen produce gamma rays via PcrPism→π{sup 0}→γγ. For a 'normal' star-forming galaxy like the Milky Way, most cosmic rays escape the Galaxy before such collisions, but in starburst galaxies with dense gas and huge star formation rate, most cosmic rays do suffer these interactions [1,2]. We construct a 'thick-target' model for starburst galaxies, in which cosmic rays are accelerated by supernovae, and escape is neglected. This model gives an upper limit to the gamma-ray emission. Only two free parameters are involved in the model: cosmic-ray proton acceleration energy rate from supernova and the proton injection spectral index. The pionic gamma-radiation is calculated from 10 MeV to 10 TeV for the starburst galaxy NGC 253, and compared to Fermi and HESS data. Our model fits NGC 253 well, suggesting that cosmic rays in this starburst are in the thick target limit, and that this galaxy is a gamma-ray calorimeter.
A tidally disrupting dwarf galaxy in the halo of NGC 253
Toloba, Elisa; Spekkens, Kristine; Crnojevic, Denija; Simon, Joshua; Guhathakurta, Puragra; Strader, Jay; Caldwell, Nelson; McLeod, Brian; Seth, Anil
We report the discovery of Scl-MM-Dw2, a new dwarf galaxy at a projected separation of $\\sim$50 kpc from NGC 253, as part of the PISCeS (Panoramic Imaging Survey of Centaurus and Sculptor) project. We measure a tip of the red giant branch distance of $3.12\\pm0.30$ Mpc, suggesting that Scl-MM-Dw2 is likely a satellite of NGC 253. We qualitatively compare the distribution of red giant branch (RGB) stars in the color-magnitude diagram with theoretical isochrones and find that it is consistent with an old, $\\sim$12 Gyr, and metal poor, $-2.3<$[Fe/H]$<-1.1$, stellar population. We also detect a small number of asymptotic giant branch stars consistent with a metal poor $2-3$ Gyr population in the center of the dwarf. Our non-detection of HI in a deep Green Bank Telescope spectrum implies a gas fraction $M_{HI}/L_V<0.02$ Msun/Lsun. The stellar and gaseous properties of Scl-MM-Dw2 suggest that it is a dwarf spheroidal galaxy. Scl-MM-Dw2 has a luminosity of $M_V=-12.1\\pm0.5$ mag and a half-light radius of $r_...
The Temperature Distribution of Dense Molecular Gas in the Center of NGC 253
Ott, J; Henkel, C; Walter, F; Ott, Juergen; Weiss, Axel; Henkel, Christian; Walter, Fabian
[abridged] We present interferometric maps of ammonia (NH3) of the nearby starburst galaxy NGC 253 [star formation rate: ~2.8 Mo yr^(-1)]. The observations have been taken with the Australia Telescope Compact Array and include the para-NH3 (1,1), (2,2), and the ortho-NH3 (3,3) and (6,6) inversion lines. Six major complexes of dense ammonia are identified, three of them on either side of the starburst center, out to projected galactocentric radii of \\~250 pc. [...] The application of radiative transfer large velocity gradient models reveals that the bulk of the ammonia molecules is embedded in a one-temperature gas phase. Kinetic temperatures of this gas are ~200 and 140 K toward the south-west and north-east [of the nucleus of NGC 253], respectively. The temperatures under which ammonia was formed in the past are with >~30 K also warmer toward the south-west than toward the north-east (~15-20 K). This is indicated by the ortho-to-para ammonia ratio which is ~1 and 1.5-2.5 toward the south-west and north-east,...
Dense gas in nearby galaxies XV. Hot ammonia in NGC253, Maffei2 and IC342
Mauersberger, R; Weiss, A; Peck, A B; Hagiwara, Y
The detection of NH3 inversion lines up to the (J,K)=(6,6) level is reported toward the central regions of the nearby galaxies NGC253, Maffei2, and IC342. The observed lines are up to 406K (for (J,K)=(6,6)) and 848K (for the (9,9) transition) above the ground state and reveal a warm (T_kin= 100 - 140 K) molecular component toward all galaxies studied. The tentatively detected (J,K)=(9,9) line is evidence for an even warmer (>400K) component toward IC342. Toward NGC253, IC342 and Maffei2 the global beam averaged NH3 abundances are 1-2 10^-8, while the abundance relative to warm H2 is around 10^-7. The temperatures and NH3 abundances are similar to values found for the Galactic central region. C-shocks produced in cloud-cloud collisions can explain kinetic temperatures and chemical abundances. In the central region of M82, however, the NH3 emitting gas component is comparatively cool (~ 30K). It must be dense (to provide sufficient NH3 excitation) and well shielded from dissociating photons and comprises only a...
晚期妊娠宫内感染253例临床分析%The clinical analysis of 253 cases of intrauterine infection in late pregnancy
Institute of Scientific and Technical Information of China (English)
林穗青; 程蔚蔚
Objective Investigate the cause of intrauterine infection in late pregnancy, the main pathogens, its impact on maternal and child outcomes and prevention measures. Methods International Peace Maternity & Child Health Hospital, Shanghai Jiao Tong University School of Medicine,253 cases was diagnosed of intrauterine infection in late pregnancy between January 1, 2006 and December 31 ,2011 were analyzed retrospectively. Results The hospital in the past of six years the number of cases to intrauterine infection accounted for 0. 41 % of the same period the total number of deliveries, including preterm intrauterine infection accounted for 2. 36% of the total number of premature delivery. Intrauterine infection is associated with premature rupture of membranes, to the time of treatment, the production process duration and the number of vaginal examinations and others. The main pathogens of intrauterine infection followed by GBS (20. 6% ) , escherichia coli (19. 4% ) , enterococcus faecalis (18. 9% ). Of the intrauterine infection patients, rate of eesarean section 76.1% , puerperal infection 14. 2% , neonatal infection 20. 9% , perinatal mortality 3. 2%. Conclusions To strengthen the health care during pregnancy and the management of treatment, the production process. Active prevention and timely diagnosis and treatment of intrauterine infection can improve the prognosis of female and children.%目的 探讨晚期妊娠宫内感染的病因、主要致病菌、对母儿的影响及防治措施.方法 对上海交通大学医学院附属国际和平妇幼保健院2006年1月1日至2011年12月31日诊断为晚期妊娠宫内感染的253例患者资料进行回顾性分析.根据分娩孕周分成早产组(82例)及足月组(171例),比较两组病例的临床结果及母儿预后等.结果 6年来宫内感染的病例数占同期分娩总数的0.41%,其中早产宫内感染占早产总数的2.36%.早产组胎膜早破率、产褥感染率、新生儿感染率及围产�
Energy Technology Data Exchange (ETDEWEB)
Davidge, T. J., E-mail: firstname.lastname@example.com [Dominion Astrophysical Observatory, National Research Council of Canada, 5071 West Saanich Road, Victoria, BC V9E 2E7 (Canada)
We discuss integral field spectra of the compact star-forming complex that is the brightest near-infrared (NIR) source in the central regions of the starburst galaxy NGC 253. The spectra cover the H and K passbands and were recorded with the Gemini NIR Spectrograph during subarcsecond seeing conditions. Absorption features in the spectrum of the star-forming complex are weaker than in the surroundings. An absorption feature is found near 1.78 μm that coincides with the location of a C{sub 2} bandhead. If this feature is due to C{sub 2} then the star-forming complex has been in place for at least a few hundred Myr. Emission lines of Brγ, [Fe ii], and He i 2.06 μm do not track the NIR continuum light. Pockets of star-forming activity that do not have associated concentrations of red supergiants, and so likely have ages <8 Myr, are found along the western edge of the complex, and there is evidence that one such pocket contains a rich population of Wolf–Rayet stars. Unless the star-forming complex is significantly more metal-poor than the surroundings, then a significant fraction of its total mass is in stars with ages <8 Myr. If the present-day star formation rate is maintained then the timescale to double its stellar mass ranges from a few Myr to a few tens of Myr, depending on the contribution made by stars older than ∼8 Myr. If—as suggested by some studies—the star-forming complex is centered on the galaxy's nucleus, which presumably contains a large population of old and intermediate-age stars, then the nucleus of NGC 253 is currently experiencing a phase of rapid growth in its stellar mass.
7 CFR 1726.253 - Prior approved contract modification related to alternative bid provision for payment to...
... AGRICULTURE ELECTRIC SYSTEM CONSTRUCTION POLICIES AND PROCEDURES Modifications to RUS Standard Contract Forms § 1726.253 Prior approved contract modification related to alternative bid provision for payment to... 7 Agriculture 11 2010-01-01 2010-01-01 false Prior approved contract modification related...
5 CFR 532.253 - Special rates or rate ranges for leader, supervisory, and production facilitating positions.
... 5 Administrative Personnel 1 2010-01-01 2010-01-01 false Special rates or rate ranges for leader....253 Special rates or rate ranges for leader, supervisory, and production facilitating positions. (a... shall establish special rates for leader, supervisory, and production facilitating positions,...
Control Effects of Snea253 Biological Seed Coating on Soybean Cyst Nematode%Snea253生物种衣剂防治大豆胞囊线虫的研究
Institute of Scientific and Technical Information of China (English)
陈立杰; 万传浩; 朱晓峰; 王媛媛; 黄姗姗; 陈井生; 段玉玺
以生防放线菌Snea253菌株发酵液为主,配合其它微生物菌株制备生物种衣剂对大豆种子进行包衣处理,于播种后30~35 d计数大豆根外胞囊数量、土壤中胞囊数量和根内线虫数量,研究了Snea253生物种衣剂对大豆胞囊线虫的防治效果.结果表明:生物种衣剂A(复配菌株Snea253+Sneb207+元素组合+助剂)在康平和大庆试验基点对大豆根和土壤中胞囊线虫的抑制率显著高于空白对照和商品种衣剂对照,生物种衣剂B(复配菌株Snea253+Sneb482+Snef1024+元素组合+助剂)和生物种衣剂C(Snea253+元素组合+助剂)与商品种衣剂效果相当.从大豆植株的长势和测产的结果可知,生物种衣剂既可促进大豆的生长发育,还可有效抑制线虫繁殖,尤其生物种衣剂A促生、增产和控制胞囊线虫的效果显著.%Fermentation liquor of actinomycetes strain Snea253 and other microbial strains were used to prepare the biological seed coating, then we treated soybean seeds by these seed coating and sew them in experimental areas in Liaoning and Heilongjiang provinces. We counted the cysts outside the soybean roots and in the soil around the roots, and different stages soybean cyst nematodes inside the roots from 30 to 35 days after seeding. The results showed that the biological seed coating A ( mixed bioeontrol microorganisms Snea253 + Sneb207 + elements + adjuvants) had significantly higher control effect than the no coated control and commodity seed coating control in the test fields. The biological seed coating B ( mixed biocontrol microorganisms Snea253 + Sneb482 + Snell024 + elements + adjuvants) and the biological seed coating C (Snea253 + elements +adjuvants) were as good as the commodity soybean seed coating. Biocontrol seed coating could not only promote soybean growth and development, but also effectively suppress soybean cyst nematode numbers around soybean roots and increase soybean yield. They are safe and reliable
Cloning and Sequence Analysis of ω-gliadin Genes from Wheat Variety Shaan 253%小麦品种陕253ω-醇溶蛋白基因的克隆及序列分析
Institute of Scientific and Technical Information of China (English)
李敏; 李哲清; 刘俊; 高翔; 陈其皎; 董剑; 赵万春; 李艳亮; 王明霞; 陈瑞佶; 庞红喜
为了获得优良品种陕253有关ω-醇溶蛋白基因的相关信息,根据已报道的ω-醇溶蛋白基因序列设计特异引物,采用PCR方法对小麦(Triticum aestivum L.)品种陕253总DNA进行扩增,回收1 000 bp左右的片段,经纯化、克隆并测序,获得5个不同的ω-醇溶蛋白新基因,命名为Gli-S253-1、Gli一S253-2、Gli-S253-3、Gli-S253-4和Gli-S253-5,GenBank登录号分别为:GQ423428、GQ423429、GQ423430、GQ423431和GQ423432.序列分析表明:(1)ω-醇溶蛋白基因沉默主要有4种类型(Q→*、I→*、R→*和W→*),并以第一种类型为主(占66.6%);(2)从三联体密码角度看,谷氨酰胺(Q)的两种编码方式最容易发生沉默突变(CAA→TAA和CAG→TAG);(3)从突变位点来看,沉默主要发生于三联体密码的第一位碱基(占77.8%),第二位碱基发生突变的频率占33.3%,但未见第三位沉默突变;GQ423428出现了罕见的ATA→TAA类沉默,同时涉及两个位点的变异;(4)就基因沉默突变的数目而言,GQ423428和GQ423429各高达6次,其中4个位点(349、373、478和592)为上述5条记录所共有;(5)从编码成熟蛋白的结构上看,沉默突变主要集中于ω-醇溶蛋白重复区,信号肽区及N-端区未发现此类变异;(6)进化分析表明,小麦族的ω-gliadin/secalin分成3支,其中小麦来源的ω-gliadin聚成一支.上述结果表明,本研究从陕253成功分离到5条存在丰富多样性的ω-醇溶蛋白编码基因,为深入研究优质的来源及分子辅助育种提供参考.
Deep H{\\alpha} Observations of NGC 253: a Very Extended and Possibly Declining Rotation Curve?
Hlavacek-Larrondo, J; Daigle, O; de Denus-Baillargeon, M -M; Marcelin, M; Epinat, B; Hernandez, O
This study presents a deep H{\\alpha} kinematical analysis of the Sculptor Group galaxy NGC253. The Fabry-Perot data were taken with the 36-cm Marseille Telescope in La Silla, Chile, using an EMCCD detector. Typical emission measures of ~0.1 cm^-6 pc are reached. The observations allow the detection of the Diffuse Ionized Gas component through [N II] emission at very large radii of 11.5', 12.8' and 19.0', on the receding side of the galaxy. No H{\\alpha} emission is observed at radii larger than the neutral component (11.5'). The very extended rotation curve confirms previous results and shows signs of a significant decline, on the order of 30 per cent vmax . Using the rotation data, mass models are constructed with and without the outer [N II] data points, and similar results are found. The declining part of the rotation curve is very well modeled, and seems to be truly declining.
Henry's Law vaporization studies and thermodynamics of einsteinium-253 metal dissolved in ytterbium
International Nuclear Information System (INIS)
The cohesive energy of metallic einsteinium determines whether einsteinium is a trivalent or divalent metal. The enthalpy of sublimation, a measure of the cohesive energy, is calculated from the partial pressures of einsteinium over an alloy. The partial pressure of 253Es has been measured over the range 470--870 K, using combined target and mass spectrometric Knudsen effusion techniques. An alloy was prepared with einsteinium dissolved in a ytterbium solvent to produce a very dilute solution. Partial pressure measurements on the alloy were amenable to the experimental technique and a data analysis using a Henry's law treatment of the data. Vapor pressure data are combined with an estimated crystal entropy S0298 and ΔC0/sub p/ for ytterbium, to produce enthalpy, entropy, and free energy functions from 298 to 1300 K. The vapor pressure of einsteinium in a dilute einsteinium--ytterbium alloy is described by the equation log P(atm) = -(6815 +- 216)/T+2.576 +- 0.337, from which we calculate for the enthalpy of sublimation of pure einsteinium ΔH0298 (second law) = 31.76 kcal/mol. The value of the enthalpy of sublimation is consistent with the conclusion that Es is a divalent metal
ALMA Multi-line Imaging of the Nearby Starburst Galaxy NGC 253
Meier, David S; Bolatto, Alberto D; Leroy, Adam K; Ott, Jürgen; Rosolowsky, Erik; Veilleux, Sylvain; Warren, Steven R; Weiss, Axel; Zwaan, Martin A; Zschaechner, Laura K
We present spatially resolved ($\\sim$50 pc) imaging of molecular gas species in the central kiloparsec of the nearby starburst galaxy NGC 253, based on observations taken with the Atacama Large Millimeter/submillimeter Array (ALMA). A total of 50 molecular lines are detected over a 13 GHz bandwidth imaged in the 3 mm band. Unambiguous identifications are assigned for 27 lines. Based on the measured high CO/C$^{17}$O isotopic line ratio ($\\gtrsim$350), we show that $^{12}$CO(1-0) has moderate optical depths. A comparison of the HCN and HCO$^{+}$ with their $^{13}$C-substituted isotopologues shows that the HCN(1-0) and HCO$^{+}$(1-0) lines have optical depths at least comparable to CO(1-0). H$^{13}$CN/H$^{13}$CO$^{+}$ (and H$^{13}$CN/HN$^{13}$C) line ratios provide tighter constraints on dense gas properties in this starburst. SiO has elevated abundances across the nucleus. HNCO has the most distinctive morphology of all the bright lines, with its global luminosity dominated by the outer parts of the central re...
Dark filaments in the galaxy NGC 253 - a boiling galactic disk -
Sofue, Y; David, F; Yoshiaki Sofue; Ken-ichi Wakamatsu
Abstract We study the morphology of dark lanes and filaments in the dust-rich galaxy NGC 253 using an unsharp-masked B-band optical photograph. Dust features are classified as `arcs', which have heights and scale radius of about 100 to 300 pc, connecting two or more dark clouds, and `loops' and `bubbles', which are developed forms of arcs, expanding into the disk-halo interface. These have diameters of a few hundred pc to \\sim 1 kpc. Among the bubbles, we notice a peculiar round-shaped bubble above the nucleus, which could be a large-diameter (\\sim 300 pc) supernova remnant exploded in the halo over the nucleus. We also find `vertical dust streamers', which comprise bunches of narrow filaments with a thickness of a few tens of pc and are almost perpendicular to the galactic plane, extending coherently for 1 to 2 kpc toward the halo. Finally, we note `short vertical dust filaments' (or spicules) are found in the central region. We interpret these features as due to three-dimensional structures of gas extending...
Dark filaments in the galaxy NGC 253: A boiling galactic disk
Sofue, Yoshiaki; Wakamatsu, Ken-Ichi; Malin, David F.
We study the morphology of dark lanes and filaments in the dust-rich galaxy NGC 253 using an unsharp-masked B-band optical photograph. Dust features are classified as 'arcs,' which have heights and scale radius of about 100 to 300 pc, connecting two or more dark clouds, and 'loops' and 'bubbles,' which are developed forms of arcs, expanding into the disk-halo interface. These have diameters of a few hundred pc to approximately 1 kpc. Among the bubbles, we notice a peculiar round-shaped bubble above the nucleus, which could be a large-diameter (approximately 300 pc) supernova remnant exploded in the halo over the nucleus. We also find 'vertical dust streamers,' which comprise bunches of narrow filaments with a thickness of a few tens of pc and are almost perpendicular to the galactic plane, extending coherently for 1 to 2 kpc toward the halo. Finally, we note 'short vertical dust filaments' (or spicules) are found in the central region. We interpret these features as due to three-dimensional structures of gas extending from the disk into the halo. We propose a 'boiling disk' model where the filamentary features are produced by star-forming activity in the disk as well as the influence of magnetic fluxes. We discuss the implication of the model for the chemical evolution of the interstellar medium (ISM) in a galaxy disk.
The NIR structure of the barred galaxy NGC253 from VISTA
Iodice, E; Rejkuba, M; Neeser, M J; Greggio, L; Gonzalez, O A; Irwin, M; Emerson, J P
[abridged] We used J and Ks band images acquired with the VISTA telescope as part of the science verification to quantify the structures in the stellar disk of the barred Sc galaxy NGC253. Moving outward from the galaxy center, we find a nuclear ring within the bright 1 kpc diameter nucleus, then a bar, a ring with 2.9 kpc radius. From the Ks image we obtain a new measure of the deprojected length of the bar of 2.5 kpc. The bar's strength, as derived from the curvature of the dust lanes in the J-Ks image, is typical of weak bars. From the deprojected length of the bar, we establish the corotation radius (R_CR=3 kpc) and bar pattern speed (Omega_b = 61.3 km /s kpc), which provides the connection between the high-frequency structures in the disk and the orbital resonances induced by the bar. The nuclear ring is located at the inner Lindblad resonance. The second ring does not have a resonant origin, but it could be a merger remnant or a transient structure formed during an intermediate stage of the bar formatio...
Radiative and mechanical feedback into the molecular gas of NGC 253
Rosenberg, M J F; van der Werf, P P; Israel, F P; Meijerink, R; Weiß, A; Requena-Torres, M A; Güsten, R
Starburst galaxies are undergoing intense periods of star formation. Understanding the heating and cooling mechanisms in these galaxies can give us insight to the driving mechanisms that fuel the starburst. Molecular emission lines play a crucial role in the cooling of the excited gas. With SPIRE on the Herschel Space Observatory we have observed the rich molecular spectrum towards the central region of NGC 253. CO transitions from J=4-3 to 13-12 are observed and together with low-J line fluxes from ground based observations, these lines trace the excitation of CO. By studying the CO excitation ladder and comparing the intensities to models, we investigate whether the gas is excited by UV radiation, X-rays, cosmic rays, or turbulent heating. Comparing the $^{12}$CO and $^{13}$CO observations to large velocity gradient models and PDR models we find three main ISM phases. We estimate the density, temperature,and masses of these ISM phases. By adding $^{13}$CO, HCN, and HNC line intensities, we are able to const...
VizieR Online Data Catalog: NGC253 near-infrared H2 emission (Rosenberg+,
Rosenberg, M. J. F.; van der Werf, P. P.; Israel, F. P.
All observations were made with SINFONI at the ESO VLT. We observed in the H, and K bands using a spatial pixel scale of 0.25" corresponding to a field of view of 8" by 8" per frame and a spectral resolution of 2000, 3000 and 4000 respectively, which corresponds to a velocity resolution of 149.8, 99.9 and 74.9km/s. All science observations were taken in the ABA'nodding mode (300s of object, 300s of sky, 300s of object), where A' is slightly offset from A. The object exposures are aligned and averaged during the reconstruction of the data cube. The observations of NGC 253 were made in visitor mode on August 28th, 2005. In order to capture the full extent of the H2 emission, consecutive frames were taken in the K band moving further away from the center, along the disk until H2 was no longer detected. This resulted in 6 separate pointings. Since there are also H2 transitions in the H band, a similar strategy was used, resulting in 4 separate pointings. We used the standard reduction techniques of the SINFONI pipeline on all observations, including corrections for flat field, dark current, nonlinearity of pixels, distortion, and wavelength calibration. We obtained the flux calibration and atmospheric corrections from observations of a standard star, namely HR 2058 in the H band and HD 20001 in the K band (2 data files).
CO (J=7->6) Observations of NGC 253 Cosmic Ray Heated Warm Molecular Gas
Bradford, C M; Stacey, G J; Bolatto, A D; Jackson, J M; Savage, M L; Davidson, J A; Higdon, S J
We report observations of the CO J=7->6 transition toward the starburst nucleus of NGC 253. This is the highest-excitation CO measurement in this source to date, and allows an estimate of the molecular gas excitation conditions. Comparison of the CO line intensities with a large velocity gradient, escape probability model indicates that the bulk of the 2-5 x 10^7 solar masses of molecular gas in the central 180 pc is highly excited. A model with T ~ 120 K, n_H_2 ~ 4.5 x 10^4 cm^-3 is consistent with the observed CO intensities as well as the rotational H2 lines observed with ISO. The inferred mass of warm, dense molecular gas is 10--30 times the atomic gas mass as traced through its [CII] and [OI] line emission. This large mass ratio is inconsistent with photodissociation region models where the gas is heated by far-UV starlight. It is also not likely that the gas is heated by shocks in outflows or cloud-cloud collisions. We conclude that the best mechanism for heating the gas is cosmic rays, which provide a ...
SMA Observations of the Extended CO(6-5) Emission in the Starburst Galaxy NGC253
Krips, Melanie; Peck, Alison; Sakamoto, Kazushi; Neri, Roberto; Gurwell, Mark; Petitpas, Glen; Zhao, Jun-Hui
We present observations of the $^{12}$CO(6-5) line and 686GHz continuum emission in NGC253 with the Submillimeter Array at an angular resolution of ~4arcsec. The $^{12}$CO(6-5) emission is clearly detected along the disk and follows the distribution of the lower $^{12}$CO line transitions with little variations of the line ratios in it. A large-velocity gradient analysis suggests a two-temperature model of the molecular gas in the disk, likely dominated by a combination of low-velocity shocks and the disk wide PDRs. Only marginal $^{12}$CO(6-5) emission is detected in the vicinity of the expanding shells at the eastern and western edges of the disk. While the eastern shell contains gas even warmer (T$_{\\rm kin}$>300~K) than the hot gas component (T$_{\\rm kin}$=300K) of the disk, the western shell is surrounded by gas much cooler (T$_{\\rm kin}$=60K) than the eastern shell but somewhat hotter than the cold gas component of the disk (for similar H$_2$ and CO column densities), indicative of different (or differe...
The Compact Star-Forming Complex at the Heart of NGC 253
Davidge, T J
We discuss integral field spectra of the compact star-forming complex that is the brightest near-infrared (NIR) source in the central regions of the starburst galaxy NGC 253. The spectra cover the H and K passbands and were recorded with the Gemini NIR Spectrograph during sub-arcsec seeing conditions. Absorption features in the spectrum of the star-forming complex are weaker than in the surroundings. An absorption feature is found near 1.78um that coincides with the location of a C2 bandhead. Emission lines of Brgamma, [FeII], and HeI2.06um do not track the NIR continuum light. Pockets of star-forming activity that do not have associated concentrations of red supergiants, and so likely have ages < 8 Myr, are found along the western edge of the complex, and there is evidence that one such pocket contains a rich population of Wolf-Rayet stars. Unless the star-forming complex is significantly more metal-poor than the surroundings, then a significant fraction of its total mass is in stars with ages < 8 Myr....
253.7nm紫外光照条件下溴对臭氧损耗影响%Affection of Bromide on the 253.7 nm Photosensitized Decomposition of Ozone
Institute of Scientific and Technical Information of China (English)
李朝敏; 张振满; 侯健; 潘循皙; 侯惠奇
In this paper quantum yield for the photosensitized decomposition of ozone in the pure O3,O3+O2(N2) systems under the irradiation of 253.7 nm is studied. The quantum yield of the depletion ozone by bromide under the condition similar to stratosphere is further determinated, the ratio of two branches of BrO+BrO reaction is 5.25±0.26.
On carbon and oxygen isotope ratios in starburst galaxies: New data from NGC253 and Mrk231 and their implications
Henkel, C; Ao, Y; Aalto, S; Danielson, A L R; Papadopoulos, P P; Garcia-Burillo, S; Aladro, R; Impellizzeri, C M V; Mauersberger, R; Martin, S; Harada, N
Using the IRAM 30-m telescope, CN and CO isotopologues have been measured toward the central regions of the nearby starburst galaxy NGC253 and the prototypical ultraluminous infrared galaxy Mrk231. In NGC253, the 12C/13C ratio is 40+-10. Assuming that the ratio also holds for the CO emitting gas, this yields 16O/18O = 145+-36 and 16O/17O = 1290+-365 and a 32S/34S ratio close to that measured for the local interstellar medium (20-25). No indication for vibrationally excited CN is found. Peak line intensity ratios between NGC253 and Mrk231 are ~100 for 12C16O and 12C18O J=1-0, while the ratio for 13C16O J=1-0 is ~250. This and similar 13CO and C18O line intensities in the J=1-0 and 2-1 transitions of Mrk231 suggest 12C/13C ~ 100 and 16O/18O ~ 100, in agreement with values obtained for the less evolved ultraluminous merger Arp220. Also accounting for other extragalactic data, 12C/13C ratios appear to vary over a full order of magnitude, from >100 in ultraluminous high redshift galaxies to ~100 in more local such...
On The GeV & TeV Detections of the Starburst Galaxies M82 & NGC 253
Lacki, Brian C; Quataert, Eliot; Loeb, Abraham; Waxman, Eli
The observed GeV and TeV emission from M82 and NGC 253 by Fermi, HESS, and VERITAS constrains the physics of cosmic rays (CRs) in these dense star-forming environments. We discuss these constraints in detail, and present an independent analysis of the Fermi data for these starbursts. We argue the gamma-rays are predominantly hadronic in origin; in this case, the measured fluxes imply that both galaxies are consistent with being CR "proton calorimeters:" all of the energy injected in high energy primary CR protons is lost to inelastic proton-proton collisions (pion production) before escape, producing gamma-rays, neutrinos, and secondary electrons and positrons. The case for calorimetry is stronger for M82 than for NGC 253, and the latter may be only marginally calorimetric. We also consider leptonic contributions to the GeV-TeV emission, including the possibility of a "TeV Excess" analogous to that seen in the Galaxy. We show that the GeV-TeV detections of M82 and NGC 253, together with proton calorimetry, im...
Spectral analysis and interpretation of the \\gamma-ray emission from the Starburst galaxy NGC 253
Abramowski, A; Aharonian, F; Akhperjanian, A G; Anton, G; Balzer, A; Barnacka, A; Becherini, Y; Becker, J; Bernlöhr, K; Birsin, E; Biteau, J; Bochow, A; Boisson, C; Bolmont, J; Bordas, P; Brucker, J; Brun, F; Brun, P; Bulik, T; Büsching, I; Carrigan, S; Casanova, S; Cerruti, M; Chadwick, P M; Charbonnier, A; Chaves, R C G; Cheesebrough, A; Cologna, G; Conrad, J; Couturier, C; Dalton, M; Daniel, M K; Davids, I D; Degrange, B; Deil, C; Dickinson, H J; Djannati-Ataï, A; Domainko, W; Drury, L O'C; Dubus, G; Dutson, K; Dyks, J; Dyrda, M; Egberts, K; Eger, P; Espigat, P; Fallon, L; Fegan, S; Feinstein, F; Fernandes, M V; Fiasson, A; Fontaine, G; Förster, A; Füßling, M; Gajdus, M; Gallant, Y A; Garrigoux, T; Gast, H; Gérard, L; Giebels, B; Glicenstein, J F; Glück, B; Göring, D; Grondin, M -H; Häffner, S; Hague, J D; Hahn, J; Hampf, D; Harris, J; Hauser, M; Heinz, S; Heinzelmann, G; Henri, G; Hermann, G; Hillert, A; Hinton, J A; Hofmann, W; Hofverberg, P; Holler, M; Horns, D; Jacholkowska, A; Jahn, C; Jamrozy, M; Jung, I; Kastendieck, M A; Katarzyński, K; Katz, U; Kaufmann, S; Khélifi, B; Klochkov, D; Kluźniak, W; Kneiske, T; Komin, Nu; Kosack, K; Kossakowski, R; Krayzel, F; Laffon, H; Lamanna, G; Lenain, J -P; Lennarz, D; Lohse, T; Lopatin, A; Lu, C -C; Marandon, V; Marcowith, A; Masbou, J; Maurin, G; Maxted, N; Mayer, M; McComb, T J L; Medina, M C; Méhault, J; Moderski, R; Mohamed, M; Moulin, E; Naumann, C L; Naumann-Godo, M; de Naurois, M; Nedbal, D; Nekrassov, D; Nguyen, N; Nicholas, B; Niemiec, J; Nolan, S J; Ohm, S; Wilhelmi, E de Oña; Opitz, B; Ostrowski, M; Oya, I; Panter, M; Arribas, M Paz; Pekeur, N W; Pelletier, G; Perez, J; Petrucci, P -O; Peyaud, B; Pita, S; Pühlhofer, G; Punch, M; Quirrenbach, A; Raue, M; Reimer, A; Reimer, O; Renaud, M; Reyes, R de los; Rieger, F; Ripken, J; Rob, L; Rosier-Lees, S; Rowell, G; Rudak, B; Rulten, C B; Sahakian, V; Sanchez, D A; Santangelo, A; Schlickeiser, R; Schulz, A; Schwanke, U; Schwarzburg, S; Schwemmer, S; Sheidaei, F; Skilton, J L; Sol, H; Spengler, G; Stawarz, Ł; Steenkamp, R; Stegmann, C; Stinzing, F; Stycz, K; Sushch, I; Szostek, A; Tavernet, J -P; Terrier, R; Tluczykont, M; Valerius, K; van Eldik, C; Vasileiadis, G; Venter, C; Viana, A; Vincent, P; Völk, H J; Volpe, F; Vorobiov, S; Vorster, M; Wagner, S J; Ward, M; White, R; Wierzcholska, A; Zacharias, M; Zajczyk, A; Zdziarski, A A; Zech, A; Zechlin, H -S
Very-high-energy (VHE; E >100 GeV) and high-energy (HE; 100 MeV < E < 100 GeV) data from \\gamma-ray observations performed with the H.E.S.S. telescope array and the Fermi-LAT instrument, respectively, are analysed in order to investigate the non-thermal processes in the starburst galaxy NGC 253. The VHE \\gamma-ray data can be described by a power law in energy with differential photon index \\Gamma=2.14 \\pm 0.18_stat \\pm 0.30_sys and differential flux normalisation at 1 TeV of F_0 = (9.6 \\pm 1.5_stat (+5.7,-2.9)_sys) x 10^{-14} TeV^{-1} cm^{-2} s^{-1}. A power-law fit to the differential HE \\gamma-ray spectrum reveals a photon index of \\Gamma=2.24 \\pm 0.14_stat \\pm 0.03_sys and an integral flux between 200 MeV and 200 GeV of F(0.2-200 GeV) = (4.9 \\pm 1.0_stat \\pm 0.3_sys) x 10^{-9} cm^{-2} s^{-1}. No evidence for a spectral break or turnover is found over the dynamic range of both the LAT instrument and the H.E.S.S. experiment: a combined fit of a power law to the HE and VHE \\gamma-ray data results in a ...
The dynamics and star-forming potential of the massive Galactic centre cloud G0.253+0.016
Johnston, K. G.; Beuther, H.; Linz, H.; Schmiedeke, A.; Ragan, S. E.; Henning, Th.
Context. The massive infrared dark cloud G0.253+0.016 projected ~45 pc from the Galactic centre contains ~105 M⊙ of dense gas whilst being mostly devoid of observed star-formation tracers. Aims: Our goals are therefore to scrutinise the physical properties, dynamics and structure of this cloud with reference to its star-forming potential. Methods: We have carried out a concerted SMA and IRAM 30 m study of this enigmatic cloud in dust continuum, CO isotopologues, several shock tracing molecules, as well as H2CO to trace the gas temperature. In addition, we include ancillary far-IR and sub-mm Herschel and SCUBA data in our analysis. Results: We detect and characterise a total of 36 dust cores within G0.253+0.016 at 1.3 mm and 1.37 mm, with masses between 25 and approximately 250 M⊙, and find that the kinetic temperature of the gas traced by H2CO ratios is >320 K on size-scales of ~0.15 pc. Analysis of the position-velocity diagrams of our observed lines shows broad linewidths and strong shock emission in the south of the cloud, indicating that G0.253+0.016 is colliding with another cloud at vLSR ~ 70 km s-1. We confirm via an analysis of the observed dynamics in the Central Molecular Zone that it is an elongated structure, orientated with Sgr B2 closer to the Sun than Sgr A*, however our results suggest that the actual geometry may be more complex than an elliptical ring. We find that the column density probability distribution function of G0.253+0.016 derived from SMA and SCUBA dust continuum emission is log-normal with no discernible power-law tail, consistent with little star formation, and that its width can be explained in the framework of theory predicting the density structure of clouds created by supersonic, magnetised turbulence. We also present the Δ-variance spectrum of this region, a proxy for the density power spectrum of the cloud, and show it is consistent with that expected for clouds with no current star formation. Finally, we show that even
AKARI Near-Infrared Spectroscopic Observations of Interstellar Ices in Edge-on Starburst Galaxy NGC253
Yamagishi, Mitsuyoshi; Ishihara, Daisuke; Oyabu, Shinki; Onaka, Takashi; Shimonishi, Takashi; Suzuki, Toyoaki
We present the spatially-resolved near-infrared (2.5-5.0 um) spectra of the edge-on starburst galaxy NGC253 obtained with the Infrared Camera onboard AKARI. Near the center of the galaxy, we clearly detect the absorption features of interstellar ices (H_2O: 3.05 um, CO_2: 4.27 um, and XCN: 4.62 um) and the emission of polycyclic aromatic hydrocarbons (PAHs) at 3.29 um and hydrogen recombination line Br alpha at 4.05 um. We find that the distributions of the ices differ from those of the PAH and gas. We calculate the column densities of the ices and derive the abundance ratios of N(CO_2)/N(H_2O) = 0.17 +- 0.05. They are similar to those obtained around the massive young stellar objects in our Galaxy (0.17 +- 0.03), although much stronger interstellar radiation field and higher dust temperature are expected near the center of NGC253.
The Galactic Center Cloud G0.253+0.016: A Massive Dense Cloud with low Star Formation Potential
Kauffmann, Jens; Zhang, Qizhou
We present the first interferometric molecular line and dust emission maps for the Galactic Center (GC) cloud G0.253+0.016, observed using the Combined Array for Research in Millimeter--wave Astronomy (CARMA) and the Submillimeter Array (SMA). This cloud is very dense, and concentrates a mass exceeding the Orion Molecular Cloud Complex (2x10^5 M_sun) into a radius of only 3pc, but it is essentially starless. G0.253+0.016 therefore violates "star formation laws" presently used to explain trends in galactic and extragalactic star formation by a factor ~45. Our observations show a lack of dense cores of significant mass and density, thus explaining the low star formation activity. Instead, cores with low densities and line widths 1km/s---probably the narrowest lines reported for the GC region to date---are found. Evolution over several 10^5 yr is needed before more massive cores, and possibly an Arches--like stellar cluster, could form. Given the disruptive dynamics of the GC region, and the potentially unbound ...
Apert Syndrome: Molecularly Confirmed C.758C>G (P.Pro253Arg) in FGFR2
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Cha Gon, Lee, E-mail: email@example.com [Department of Pediatrics, Eulji General Hospital, College of Medicine, Eulji University, 68 Hangeulbiseok-ro, Nowon-gu, Seoul 139-711 (Korea, Republic of)
A 5-day-old girl was referred to our clinic for evaluation of congenital malformations. She was identified with a pathogenic mutation c.758C>G (p.Pro253Arg) in FGFR2 gene using targeted exome sequencing. The de novo mutation was confirmed with Sanger sequencing in the patient and her parents. She showed occipital plagiocephaly with frontal bossing (Figure A and B). Skull frontal and lateral radiography revealed fusion of most of the sutures except coronal suture, with convolutional markings (Figure D and E). She had complete cleft palate (Figure C). Her fused bilateral hands showed type II syndactyly with complete syndactyly between the ring and the little fingers (Figure F1-F3). Both toes were simple syndactyly with side-to-side fusion of skin (Figure G1-)
Apert Syndrome: Molecularly Confirmed C.758C>G (P.Pro253Arg) in FGFR2
International Nuclear Information System (INIS)
A 5-day-old girl was referred to our clinic for evaluation of congenital malformations. She was identified with a pathogenic mutation c.758C>G (p.Pro253Arg) in FGFR2 gene using targeted exome sequencing. The de novo mutation was confirmed with Sanger sequencing in the patient and her parents. She showed occipital plagiocephaly with frontal bossing (Figure A and B). Skull frontal and lateral radiography revealed fusion of most of the sutures except coronal suture, with convolutional markings (Figure D and E). She had complete cleft palate (Figure C). Her fused bilateral hands showed type II syndactyly with complete syndactyly between the ring and the little fingers (Figure F1-F3). Both toes were simple syndactyly with side-to-side fusion of skin (Figure G1-)
Analysis of t(9;17)(q33.2;q25.3) chromosomal breakpoint regions and genetic association reveals novel candidate genes for bipolar disorder
DEFF Research Database (Denmark)
Rajkumar, Anto P; Christensen, Jane H; Mattheisen, Manuel;
-linked Danish psychiatric and cytogenetic case registers to identify an individual with both t(9;17)(q33.2;q25.3) and BD. Fluorescent in situ hybridization was employed to map the chromosomal breakpoint regions of this proband. We accessed the Psychiatric Genomics Consortium BD (n = 16,731) and SZ (n = 21...
Detection and analysis of pathogenic microorganism in the stool specimens from 253 chronic diarrhea patients with HIV infection%253例HIV感染合并慢性腹泻患者粪便标本的病原微生物检测分析
Institute of Scientific and Technical Information of China (English)
王慧珠; 华文浩; 李敏; 田敬华; 张燕; 王玉光; 李兴旺; 赵辉
Objective To investigate the pathogenic profiles of chronic diarrhea patients with AIDS, for the better prevention and treatment. Methods The stool specimens in AIDS patients with chronic diarrhea were analyzed by the smear and dyeing detection method. Detection methods included direct smear for the detection of Giardia lamblia stiles, Grain stain method for fungi and mold, acid fast stain ( Ziehl-Neelsen ) for Mycobacterium, improved acid fast stain for the detection of Cryptosporidium. Stool isolation culture to identify Shigella dysenteriae, Salmonella Typhi, enteroinvasive E. Coli and fungi; aerobic culture to identify campylobacter, gold-labeled antibodies method for the detection of C. Difficile. Results Total of 159 strains of bacteria were identified, including fungi 45% ( 114/253 ) and Cryptosporidium 12.6% ( 32/253 ), Mycobacterium 2. 4% ( 6/253 ), C. Difficile 1. 58% ( 4/253 ), campylobacter 0. 8% (2/253 ), salmonella 0. 4%( 1/253 ). Conclusions Fungi, Cryptosporidium, Mycobacterium, C. Difficile. Are the major pathogens for chronic diarrhea in patients with AIDS. The identification of pathogen could make the prevention and treatment proceeding faster and better.%目的 探讨HIV感染者慢性腹泻的病原学种类及其特点,使患者得到及时的预防和治疗.方法 对253例慢性腹泻HIV感染者的粪便标本首先进行了涂片及染色检测,直接涂片检测蓝氏贾第鞭毛虫,采用革兰染色检测真菌孢子及菌丝,抗酸染色(萋-尼氏染色法)检测分枝杆菌,用改良抗酸染色法检测隐孢子虫,采用常规粪便培养检测志贺菌、沙门菌、肠侵袭性大肠埃希菌及真菌,采用微需氧培养检测空肠弯曲菌,采用金标法检测难辨梭状芽孢杆菌毒素(A+B).结果 本研究共检测出各种病原微生物159株,其中真菌最多,占45%(114/253),隐胞子虫占12.6%(32/253),结核分枝杆菌占2.4%(6/253),难辨梭状芽孢杆菌占1.58%(4/253),空肠弯曲菌占0.8%(2/253),�
Study of cyclic oxidation for stainless steels AISI 309 T 253 M A, with low additions of cerium; Estudio de la oxidacion ciclica de los aceros inoxidables AISI 309 T 253 MA, con pequenas adiciones de Cerio
Energy Technology Data Exchange (ETDEWEB)
Velazquez F, G.L.; Martinez, M.; Ruiz, A. [Universidad Nacional Experimental Politecnica (UNEXPO) - Vicerrectorado de Puerto Ordaz, Centro de Estudios de Corrosion. Puerto Ordaz. venezuela (Venezuela)
It has been detected that the addition of small amounts (<1%) of the so called `reactive elements` such as Cerium to Fe-Cr alloys that was utilized in oxidating environment at high temperatures improving its resistance to oxidation under isothermal and cyclic conditions. In this work, it was evaluated the behavior under cyclic oxidation conditions for an austenitic stainless steel at chromium-nickel (253MA) with cerium addition, and comparing it with the AISI 310S austenitic stainless steel. The cyclic oxidation essays consist of five cycles by 24 hours each one, following of a cooling in air until ambient temperature from the temperatures of 850, 900 and 950 Centigrade, registering the gain mass of the specimen at end of each cycle. In order to this were prepared samples with dimensions of 20 mm. x 10 mm. x 1 mm. Later to the oxidation essays was evaluated the morphology of the corrosion products layer by scanning electron microscopy. The present phases were identified by X-ray diffraction and by chemical microanalysis by Dispersive energy (EDAX). The results obtained show that the steel with cerium addition, presents a higher adherence and resistance to the spalling noting that the cerium promotes the casting anchor of the oxides layer to matrix and by reducing the grain size of the layer improving its plasticity. Additionally the cerium promotes the preferential oxidation of the forming elements of protective layers like the chromium. (Author)
Nustar and Chandra insight into the nature of the 3-40 kev nuclear emission in NGC 253
DEFF Research Database (Denmark)
Lehmer, B. D.; Wik, D. R.; Hornschemeier, A. E.;
We present results from three nearly simultaneous Nuclear Spectroscopic Telescope Array ( NuSTAR ) and Chandra monitoring observations between 2012 September 2 and 2012 November 16 of the local star-forming galaxy NGC 253. The 3-40 keV intensity of the inner ~ 20 arcsec ( ~ 400 pc) nuclear region......, as measured by NuSTAR , varied by a factor of ~ 2 across the three monitoring observations. The Chandra data reveal that the nuclear region contains three bright X-ray sources, including a luminous ( L2-10 keV ~ few × 1039 erg s-1 ) point source located ~ 1 arcsec from the dynamical center of the galaxy...... (within the 3σ positional uncertainty of the dynamical center); this source drives the overall variability of the nuclear region at energies ≳3 keV. We make use of the variability to measure the spectra of this single hard X-ray source when it was in bright states. The spectra are well described...
Percutaneous vertebroplasty in 1,253 levels: results and long-term effectiveness in a single centre
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Masala, Salvatore; Mastrangeli, Roberta; Petrella, Maria Chiara; Massari, Francesco; Ursone, Antonio; Simonetti, Giovanni [Universita di Roma ' ' Tor Vergata' ' , Department of Diagnostic and Molecular Imaging, Interventional Radiology and Radiotherapy, Rome (Italy)
Several authors claim that vertebroplasty (PVT) is a successful technique, but long-term effectiveness is still debated. Our goal was to evaluate the effectiveness of PVT in patients with symptomatic vertebral fractures that had not responded to conservative treatment. In our centre, 624 patients with 1,253 compression fractures were treated by PVT. Imaging studies, clinical visits and short- and long-term follow-up were assessed by visual analogue scale (VAS) testing of pain. Statistical analysis was performed to evaluate pain response after PVT (paired two-tailed t-test) and to assess any differences in pain due to different lesions (ANOVA test). We found a statistically significant improvement in the patients' quality of life, particularly in pain (P<0.001). The average VAS value pre-PVT was 8.0{+-}2.5, which significantly dropped to 1.5{+-}0.4 by 12 months. There were no significant differences in pain response between the groups of patients with different underlying disease. There was a low complication rate in our study. PVT should be considered the treatment of choice in vertebral fractures with refractory pain. With strict evaluation of the clinical indications and subspecialised operators, long-term effectiveness is probable. (orig.)
Creep rupture of the 21Cr 11Ni Si N REM stainless steel 253MA - Data collation and assessment
Energy Technology Data Exchange (ETDEWEB)
Linde, Lars; Sandstroem, R.
Creep data for the heat resistant austenitic stainless steel 253MA (21Cr 11Ni 1.7Si 0.17N REM) have been collated and assessed as part of the work in the European Creep Collaborative Committee (ECCC) Working Group (WG) 3.3. The data were assessed using the guidelines provided by ECCC WG 1. In the present assessment, two methods using different types of time-temperature parameters (TTP) have been utilised. One of the methods, the Free Temperature Method (FTM) represents a new approach, which takes into account the slope changes in the stress-time relationships with temperature. The other method, the Averaging Method (AM), was based on conventional TTPs. Post-assessment tests, also proposed by ECCC, were applied to the results of both methods. The requirements in the post-assessment tests were all met by the AM and, except in one case, by the FTM. However, creep rupture values from the FTM for this steel were found to provide and accurate description of the material behaviour and were recommended for use in the European Standard 3 refs, 15 figs, 3 tabs
Acute kidney injury in a tropical country: a cohort study of 253 patients in an infectious diseases intensive care unit
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Elizabeth De Fransceco Daher
Full Text Available Introduction: Acute kidney injury (AKI is a frequent and potentially fatal complication in infectious diseases. The aim of this study was to investigate the clinical aspects of AKI associated with infectious diseases and the factors associated with mortality. Methods: This retrospective study was conducted in patients with AKI who were admitted to the intensive care unit (ICU of a tertiary infectious diseases hospital from January 2003 to January 2012. The major underlying diseases and clinical and laboratory findings were evaluated. Results: A total of 253 cases were included. The mean age was 46±16 years, and 72% of the patients were male. The main diseases were human immunodeficiency virus (HIV infection, HIV/acquired immunodeficiency syndrome (AIDS (30%, tuberculosis (12%, leptospirosis (11% and dengue (4%. Dialysis was performed in 70 cases (27.6%. The patients were classified as risk (4.4%, injury (63.6% or failure (32%. The time between AKI diagnosis and dialysis was 3.6±4.7 days. Oliguria was observed in 112 cases (45.7%. The Acute Physiology and Chronic Health Evaluation (APACHE II scores were higher in patients with HIV/AIDS (57±20, p-value=0.01 and dengue (68±11, p-value=0.01. Death occurred in 159 cases (62.8%. Mortality was higher in patients with HIV/AIDS (76.6%, p-value=0.02. A multivariate analysis identified the following independent risk factors for death: oliguria, metabolic acidosis, sepsis, hypovolemia, the need for vasoactive drugs, the need for mechanical ventilation and the APACHE II score. Conclusions: AKI is a common complication in infectious diseases, with high mortality. Mortality was higher in patients with HIV/AIDS, most likely due to the severity of immunosuppression and opportunistic diseases.
Effect of UV irradiation (253.7 nm) on free Legionella and Legionella associated with its amoebae hosts.
Cervero-Aragó, Sílvia; Sommer, Regina; Araujo, Rosa M
Water systems are the primary reservoir for Legionella spp., where the bacteria live in association with other microorganisms, such as free-living amoebae. A wide range of disinfection treatments have been studied to control and prevent Legionella colonization but few of them were performed considering its relation with protozoa. In this study, the effectiveness of UV irradiation (253.7 nm) using low-pressure lamps was investigated as a disinfection method for Legionella and amoebae under controlled laboratory conditions. UV treatments were applied to 5 strains of Legionella spp., 4 strains of free-living amoeba of the genera Acanthamoeba and Vermamoeba, treating separately trophozoites and cysts, and to two different co-cultures of Legionella pneumophila with the Acanthamoeba strains. No significant differences in the UV inactivation behavior were observed among Legionella strains tested which were 3 logs reduced for fluences around 45 J/m(2). UV irradiation was less effective against free-living amoebae; which in some cases required up to 990 J/m(2) to obtain the same population reduction. UV treatment was more effective against trophozoites compared to cysts; moreover, inactivation patterns were clearly different between the genus Acanthamoeba and Vermamoeba. For the first time data about Vermamoeba vermiformis UV inactivation has been reported in a study. Finally, the results showed that the association of L. pneumophila with free-living amoebae decreases the effectiveness of UV irradiation against the bacteria in a range of 1.5-2 fold. That fact demonstrates that the relations established between different microorganisms in the water systems can modify the effectiveness of the UV treatments applied.
Biological, chemical and other data collected aboard the THOMAS G. THOMPSON during cruise TN253 in the North Pacific Ocean from 2010-08-26 to 2010-09-07 (NODC Accession 0104358)
National Oceanic and Atmospheric Administration, Department of Commerce — NODC accession 0104358 includes biological, chemical, optical, physical and underway data collected aboard the THOMAS G. THOMPSON during cruise TN253 in the North...
Spontaneous growth pattern in 253 Chinese girls with Turner′s syndrome%253例中国Turner综合征患者的自然生长曲线
Institute of Scientific and Technical Information of China (English)
中华医学会儿科学分会内分泌遗传代谢学组; Turner综合征生长方式研究协作组
Objective To analyze the spontaneous growth pattern in Chinesegirls with Turner′s syndrome (TS), and to make Chinese TS growth curves for clinical practice. Methods The pretreatment mixed longitudinal and cross-sectional height, weight and bone age measurements of 253 patients with Turner′s syndrome from 8 hospitals of 5 provinces in China were analyzed. The measurements were obtained from patients aged from birth to 30 years. It was required that only one observation should be included per year for one child. A total of 289 height measurements and 106 bone age measurements were obtained. The Chinese TS growth curves were developed by curve estimation and compared with that of the normal girls. Height z scores (HtSDS) of the TS girls were calculated according to the development data of normal girls from 9 cities of China. Weight for height z scores (HtWSDS) of TS patients were calculated according to the patients′ actual height and weight. Results Mean birth length (n=6) was (47.2±2.5) cm, mean height z score (HtSDS) of the birth length was -1.52. The difference between the mean height of TS and the normal girls of the same age gradually increased from 8.03 cm at the age of 3 years to 27.89 cm at the age of 13 years, it gradually decreased to 18.87 cm at the age of 20 years. Mean adult height was (140.0±7.9) cm. The ~(+2s)area of TS patients′ growth curves and the ~(-2s)area of the normal growth curves were in the same range before the age of 8 years, which became partly different from 8 years old children and completely different at 13-14 years of age. There was no evidence of a pubertal height spurt in TS girls. Bone age was increasingly retarded, it was less than 2 years below chronological age before 12 years of age and more than 3 years below chronological age after the age of 13 years. Mean HtWSDS of all age groups were above the means of the normal girls except for that of the 4-year-old group, which was -0.55. Mean HtWSDS of the
Nustar and Chandra Insight into the Nature of the 3-40 Kev Nuclear Emission in Ngc 253
Lehmer, Bret D.; Wik, Daniel R.; Hornschemeier, Ann E.; Ptak, Andrew; Antoniu, V.; Argo, M.K.; Bechtol, K.; Boggs, S.; Christensen, F.E.; Craig, W.W.; Hailey, C.J.; Harrison, F.A.; Krivonos, R.; Leyder, Jean-Christophe Xavier Georges; Maccarone, T.J.; Stern, D.; Venters, T.; Zezas, A.; Zhang, W.W.
We present results from three nearly simultaneous Nuclear Spectroscopic Telescope Array (NuSTAR) and Chandra monitoring observations between 2012 September 2 and 2012 November 16 of the local star-forming galaxy NGC 253. The 3-40 kiloelectron volt intensity of the inner approximately 20 arcsec (approximately 400 parsec) nuclear region, as measured by NuSTAR, varied by a factor of approximately 2 across the three monitoring observations. The Chandra data reveal that the nuclear region contains three bright X-ray sources, including a luminous (L (sub 2-10 kiloelectron volt) approximately few × 10 (exp 39) erg per s) point source located approximately 1 arcsec from the dynamical center of the galaxy (within the sigma 3 positional uncertainty of the dynamical center); this source drives the overall variability of the nuclear region at energies greater than or approximately equal to 3 kiloelectron volts. We make use of the variability to measure the spectra of this single hard X-ray source when it was in bright states. The spectra are well described by an absorbed (power-law model spectral fit value, N(sub H), approximately equal to 1.6 x 10 (exp 23) per square centimeter) broken power-law model with spectral slopes and break energies that are typical of ultraluminous X-ray sources (ULXs), but not active galactic nuclei (AGNs). A previous Chandra observation in 2003 showed a hard X-ray point source of similar luminosity to the 2012 source that was also near the dynamical center (Phi is approximately equal to 0.4 arcsec); however, this source was offset from the 2012 source position by approximately 1 arcsec. We show that the probability of the 2003 and 2012 hard X-ray sources being unrelated is much greater than 99.99% based on the Chandra spatial localizations. Interestingly, the Chandra spectrum of the 2003 source (3-8 kiloelectron volts) is shallower in slope than that of the 2012 hard X-ray source. Its proximity to the dynamical center and harder Chandra spectrum
SPATIALLY RESOLVING A STARBURST GALAXY AT HARD X-RAY ENERGIES: NuSTAR, CHANDRA, AND VLBA OBSERVATIONS OF NGC 253
Energy Technology Data Exchange (ETDEWEB)
Wik, D. R.; Lehmer, B. D.; Hornschemeier, A. E.; Yukita, M.; Ptak, A.; Venters, T.; Zhang, W. W. [NASA Goddard Space Flight Center, Code 662, Greenbelt, MD 20771 (United States); Zezas, A. [Physics Department, University of Crete, Heraklion (Greece); Antoniou, V. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Argo, M. K. [ASTRON, The Netherlands Institute for Radio Astronomy, Postbus 2, 7990-AA Dwingeloo (Netherlands); Bechtol, K. [Kavli Institute for Cosmological Physics, Chicago, IL 60637 (United States); Boggs, S.; Craig, W.; Krivonos, R. [U.C. Berkeley Space Sciences Laboratory, Berkeley, CA (United States); Christensen, F. [National Space Institute, Technical University of Denmark, DK-2100 Copenhagen (Denmark); Hailey, C. [Columbia University, New York, NY (United States); Harrison, F. [Caltech Division of Physics, Mathematics and Astronomy, Pasadena, CA (United States); Maccarone, T. J. [Department of Physics, Texas Tech University, Lubbock, TX 79409 (United States); Stern, D. [Jet Propulsion Laboratory, California Institute of Technology, Pasadena, CA 91109 (United States)
Prior to the launch of NuSTAR, it was not feasible to spatially resolve the hard (E > 10 keV) emission from galaxies beyond the Local Group. The combined NuSTAR data set, comprised of three ∼165 ks observations, allows spatial characterization of the hard X-ray emission in the galaxy NGC 253 for the first time. As a follow up to our initial study of its nuclear region, we present the first results concerning the full galaxy from simultaneous NuSTAR, Chandra, and Very Long Baseline Array monitoring of the local starburst galaxy NGC 253. Above ∼10 keV, nearly all the emission is concentrated within 100'' of the galactic center, produced almost exclusively by three nuclear sources, an off-nuclear ultraluminous X-ray source (ULX), and a pulsar candidate that we identify for the first time in these observations. We detect 21 distinct sources in energy bands up to 25 keV, mostly consisting of intermediate state black hole X-ray binaries. The global X-ray emission of the galaxy—dominated by the off-nuclear ULX and nuclear sources, which are also likely ULXs—falls steeply (photon index ≳ 3) above 10 keV, consistent with other NuSTAR-observed ULXs, and no significant excess above the background is detected at E > 40 keV. We report upper limits on diffuse inverse Compton emission for a range of spatial models. For the most extended morphologies considered, these hard X-ray constraints disfavor a dominant inverse Compton component to explain the γ-ray emission detected with Fermi and H.E.S.S. If NGC 253 is typical of starburst galaxies at higher redshift, their contribution to the E > 10 keV cosmic X-ray background is <1%.
Association between 17q25.3-rs6465657 polymorphism and prostate cancer susceptibility: a meta-analysis based on 19 studies
Jiang, Xiao; Zhang, Mei; Bai, Xiao-Yan; Li, Shujing; Wu, Huijian
Background Genome-wide association studies have identified rs6465657 polymorphism at chromosome 17q25.3 as a new prostate cancer (PCa) susceptibility locus in people of European descent. However, subsequent replication studies have yielded inconsistent results among different ethnicities. In this study, a comprehensive meta-analysis was conducted to systematically evaluate the relationship between rs6465657 polymorphism and PCa risk. Methods All the articles involved were identified from PubMed, EMBASE, Web of Science, EBSCO databases, and Google Scholar before December 2015. The odds ratios (ORs) with corresponding 95% confidence internals (95% CIs) were pooled under the allele model. Fourteen eligible articles with 19 studies were finally included. Results In the overall population, the 17q25.3-rs6465657C allele was found to be significantly associated with increased risk of PCa compared to the T allele (OR =1.097; 95% CI: 1.061–1.134; P<0.001). In the subgroup analysis stratified by ethnicity, significantly increased risk was found in the Caucasian population (OR =1.120; 95% CI: 1.078–1.162; P<0.001), while the difference of OR did not reach the statistical significance in the Asian or African-American population. The analyses of sensitivity indicated the robust stability of the results, and the Begg's and Egger's test indicated that no publication bias existed. Conclusion The current meta-analysis suggested that the 17q25.3-rs6465657 polymorphism could be associated with PCa susceptibility, especially in the Caucasians, while this association might be different in other ethnicities. PMID:27524905
El Límite a la Protección de las Tierras Indígenas de la Ley 19.253
Directory of Open Access Journals (Sweden)
Mario Salamanca Huenchullán
Full Text Available Este trabajo aborda el tema del límite a la protección de las tierras indígenas, que como una exigencia del interés nacional introduce en la legislación chilena la Ley Indígena 19.253, en su relación con la expropiación para la construcción de obras públicas, que en virtud de la utilidad pública se construyen sobre estas mismas tierras.
Nuevos resultados sobre la cinem\\'atica global y nuclear de NGC 253: movimientos no circulares y emisi\\'on en Br-gamma
Camperi, J A; Diaz, R J; Aguero, M P; Gimeno, G; Pessev, P
Continuing with previous research (Camperi et al. 2011),new heliocentric radial velocity distributions are presented for the nearby galaxy NGC 253, obtained from the ionized hydrogen recombination line H-alpha. These distributions have been derived from long-slit spectroscopy for various position angles. It is also shown the heliocentric radial velocity distribution corresponding to part of the infrared data (ionized hydrogen recombination line Br-gamma) observed with the Phoenix spectrograph of the Gemini South Observatory. Sequential mapping with the long slit using this instrument will enable to study in detail the kinematics of the galaxy's core, which is strongly obscured by dust.
Compressibility and thermal expansion of hydrous ringwoodite with 2.5(3) wt% H[subscript 2]O
Energy Technology Data Exchange (ETDEWEB)
Ye, Yu; Brown, David A.; Smyth, Joseph R.; Panero, Wendy R.; Jacobsen, Steven D.; Chang, Yun-Yuan; Townsend, Joshua P.; Thomas, Sylvia-Monique; Hauri, Erik H.; Dera, Przemyslaw; Frost, Daniel J. (Bayreuth); (Colorado); (CIW); (UC); (NWU); (OSU)
Ringwoodite ({gamma}-Mg{sub 2}SiO{sub 4}) is the stable polymorph of olivine in the transition zone between 525-660 km depth, and can incorporate weight percent amounts of H{sub 2}O as hydroxyl, with charge compensated mainly by Mg vacancies (Mg{sup 2+} = 2H{sup +}), but also possibly as (Si{sup 4+} = 4H{sup +} and Mg{sup 2+} + 2H{sup +} = Si{sup 4+}). We synthesized pure Mg ringwoodite containing 2.5(3) wt% H{sub 2}O, measured by secondary ion mass spectrometry (SIMS), and determined its compressibility at 300 K by single-crystal and powder X-ray diffraction (XRD), as well as its thermal expansion behavior between 140 and 740 K at room pressure. A third-order Birch-Murnaghan equation of state (BM3 EOS) fits values of the isothermal bulk modulus K{sub T0} = 159(7) GPa and (dK{sub T}/dP){sub P = 0} = K' = 6.7(7) for single-crystal XRD; K{sub T0} = 161(4) GPa and K' = 5.4(6) for powder XRD, with K{sub T0} = 160(2) GPa and K' = 6.2(3) for the combined data sets. At room pressure, hydrous ringwoodite breaks down by an irreversible unit-cell expansion above 586 K, which may be related to dehydration and changes in the disorder mechanisms. Single-crystal intensity data were collected at various temperatures up to 736 K, and show that the cell volume V(cell) has a mean thermal expansion coefficient {alpha}{sub V0} of 40(4) x 10{sup -6}/K (143-736 K), and 29(2) x 10{sup -6}/K (143-586 K before irreversible expansion). V(Mg) have {alpha}{sub 0} values of 41(3) x 10{sup -6}/K (143-736 K), and V(Si) has {alpha}{sub 0} values of 20(3) x 10{sup -6}/K (143-586 K) and 132(4) x 10{sup -6}K (586-736 K). Based on the experimental data and previous work from {sup 29}Si NMR, we propose that during the irreversible expansion, a small amount of H{sup +} cations in Mg sites transfer to Si sites without changing the cubic spinel structure of ringwoodite, and the substituted Si{sup 4+} cations move to the normally vacant octahedral site at (1/2, 1/2, 0). Including new SIMS
The link between turbulence, magnetic fields, filaments, and star formation in the Central Molecular Zone cloud G0.253+0.016
Federrath, C; Longmore, S N; Kruijssen, J M D; Bally, J; Contreras, Y; Crocker, R M; Garay, G; Jackson, J M; Testi, L; Walsh, A J
Star formation is primarily controlled by the interplay between gravity, turbulence, and magnetic fields. However, the turbulence and magnetic fields in molecular clouds near the Galactic Center may differ substantially from spiral-arm clouds. Here we determine the physical parameters of the central molecular zone (CMZ) cloud G0.253+0.016, its turbulence, magnetic field and filamentary structure. Using column-density maps based on dust-continuum emission observations with ALMA+Herschel, we identify filaments and show that at least one dense core is located along them. We measure the filament width W_fil=0.17$\\pm$0.08pc and the sonic scale {\\lambda}_sonic=0.15$\\pm$0.11pc of the turbulence, and find W_fil~{\\lambda}_sonic. A strong velocity gradient is seen in the HNCO intensity-weighted velocity maps obtained with ALMA+Mopra, which is likely caused by large-scale shearing of G0.253+0.016, producing a wide double-peaked velocity PDF. After subtracting the gradient to isolate the turbulent motions, we find a near...
Spatially Resolving a Starburst Galaxy at Hard X-ray Energies: NuSTAR, Chandra, AND VLBA Observations of NGC 253
Wik, Daniel R; Hornschemeier, Ann E; Yukita, Mihoko; Ptak, Andrew; Zezas, Andreas; Antoniou, Vallia; Argo, Megan K; Bechtol, Keith; Boggs, Steven; Christensen, Finn; Craig, William; Hailey, Charles; Harrison, Fiona; Krivanos, Roman; Maccarone, Thomas J; Stern, Daniel; Venters, Tonia; Zhang, William W
Prior to the launch of NuSTAR, it was not feasible to spatially resolve the hard (E > 10 keV) emission from galaxies beyond the Local Group. The combined NuSTAR dataset, comprised of three ~165 ks observations, allows spatial characterization of the hard X-ray emission in the galaxy NGC 253 for the first time. As a follow up to our initial study of its nuclear region, we present the first results concerning the full galaxy from simultaneous NuSTAR, Chandra, and VLBA monitoring of the local starburst galaxy NGC 253. Above ~10 keV, nearly all the emission is concentrated within 100" of the galactic center, produced almost exclusively by three nuclear sources, an off-nuclear ultraluminous X-ray source (ULX), and a pulsar candidate that we identify for the first time in these observations. We detect 21 distinct sources in energy bands up to 25 keV, mostly consisting of intermediate state black hole X-ray binaries. The global X-ray emission of the galaxy - dominated by the off-nuclear ULX and nuclear sources, whic...
Association between 17q25.3-rs6465657 polymorphism and prostate cancer susceptibility: a meta-analysis based on 19 studies
Directory of Open Access Journals (Sweden)
Jiang X
Full Text Available Xiao Jiang,1,2 Mei Zhang,3 Xiao-Yan Bai,1 Shujing Li,1 Huijian Wu1 1Laboratory of Molecular Medicine & Pharmacy, School of Life Science and Biotechnology, Dalian University of Technology, Dalian, People's Republic of China; 2Department of Gastroenterology, Dalian Municipal Central Hospital Affiliated of Dalian Medical University, Dalian, People's Republic of China; 3Department of Biochemistry and Molecular Biology, Heilongjiang University of Chinese Medicine, Haerbin, People's Republic of China Background: Genome-wide association studies have identified rs6465657 polymorphism at chromosome 17q25.3 as a new prostate cancer (PCa susceptibility locus in people of European descent. However, subsequent replication studies have yielded inconsistent results among different ethnicities. In this study, a comprehensive meta-analysis was conducted to systematically evaluate the relationship between rs6465657 polymorphism and PCa risk.Methods: All the articles involved were identified from PubMed, EMBASE, Web of Science, EBSCO databases, and Google Scholar before December 2015. The odds ratios (ORs with corresponding 95% confidence internals (95% CIs were pooled under the allele model. Fourteen eligible articles with 19 studies were finally included.Results: In the overall population, the 17q25.3-rs6465657C allele was found to be significantly associated with increased risk of PCa compared to the T allele (OR =1.097; 95% CI: 1.061–1.134; P<0.001. In the subgroup analysis stratified by ethnicity, significantly increased risk was found in the Caucasian population (OR =1.120; 95% CI: 1.078–1.162; P<0.001, while the difference of OR did not reach the statistical significance in the Asian or African-American population. The analyses of sensitivity indicated the robust stability of the results, and the Begg's and Egger's test indicated that no publication bias existed.Conclusion: The current meta-analysis suggested that the 17q25.3-rs6465657
Measurements of the viscosity of carbon dioxide at temperatures from (253.15 to 473.15) K with pressures up to 1.2 MPa
International Nuclear Information System (INIS)
Highlights: • A new rotating-body viscometer for the low-pressure region was presented. • A viscosity dependent offset was compensated by calibrating the viscometer. • The viscosity of carbon dioxide was measured at low pressures. • Measurements were carried out from T = (253.15 to 473.15) K with p ≤ 1.2 MPa. • The relative expanded combined uncertainty (k = 2) was Ur,c(η) = (0.20 to 0.41)%. - Abstract: The viscosity of carbon dioxide was measured over the temperature range T = (253.15 to 473.15) K with pressures up to 1.2 MPa utilizing a new rotating-body viscometer. The relative expanded combined uncertainty (k = 2) in viscosity (including uncertainties of temperature and pressure) was (0.20 to 0.41)%. The instrument was specifically designed for measurements at low gas densities and enables measurements of the dynamic viscosity at temperatures between T = 253.15 K and T = 473.15 K with pressures up to 2 MPa. For carbon dioxide, the fluid specific measuring range with regard to pressure was limited to 1.2 MPa due to the formation of disturbing vortices inside the measuring cell at higher pressures. The model function for the viscosity measurement was extended in such a way that the dynamic viscosity was measured relative to helium. Therefore, the influence of the geometry of the concentric cylindrical system inside the measuring cell became almost negligible. Moreover, a systematic offset resulting from a small but inevitable eccentricity of the cylindrical system was compensated for. The residual damping, usually measured in vacuum, was calibrated in the entire temperature range using viscosity values of helium, neon and argon calculated ab initio; at T = 298.15 K recommended reference values were used. A viscosity dependent offset of the measured viscosities, which was observed in previously published data, did not occur when using the calibrated residual damping. The new carbon dioxide results were compared to other experimental literature data
International Nuclear Information System (INIS)
We report the detection of high-energy γ-ray emission from two starburst galaxies using data obtained with the Large Area Telescope on board the Fermi Gamma-ray Space Telescope. Steady point-like emission above 200 MeV has been detected at significance levels of 6.8σ and 4.8σ, respectively, from sources positionally coincident with locations of the starburst galaxies M82 and NGC 253. The total fluxes of the sources are consistent with γ-ray emission originating from the interaction of cosmic rays with local interstellar gas and radiation fields and constitute evidence for a link between massive star formation and γ-ray emission in star-forming galaxies.
Synthesis and Crystal Structure of (E)-Ethyl 2-(5-(3-methyl-2-butenyloxy)-2-(3-(4-(3-methyl2-butenyloxy)phenyl)acryloyl)phenoxy)acetate
Institute of Scientific and Technical Information of China (English)
WANG Jian-Guo; WU Lin; ZHONG Chan-Juan; QI Xiao-Yan; ZHOU Jin-Xia; YI De-Lian
The title compound, (E)-ethyl 2-(5-(3-methyl-2-butenyloxy)-2-(3-(4-(3-methyl-2-butenyloxy)phenyl) acryloyl) phenoxy)acetate (1), has been synthesized and characterized by FT-IR and 1H-NMR spectroscopy, ESI-MS, and X-ray single-crystal diffraction.FT-IR, 1H-NMR and ESI-MS confirm the functional groups, particularly the ethyl groups in the ester moiety, of the compound.The single-crystal X-ray diffraction has revealed a monoclinic structure, space group P21/n with a = 14.6832(14), b = 7.7581(7), c = 23.075(2) (A), β = 101.670(2)°, V= 2574.2(4) (A)3, Z = 4,Dc = 1.235 g/cm3,μ = 0.085 mm-1, and F(000) = 1024.The skeleton of chalcone in the molecular structure is coplanar.
Co-regulation analysis of closely linked genes identifies a highly recurrent gain on chromosome 17q25.3 in prostate cancer
International Nuclear Information System (INIS)
Transcriptional profiling of prostate cancer (PC) has unveiled new markers of neoplasia and allowed insights into mechanisms underlying this disease. Genomewide analyses have also identified new chromosomal abnormalities associated with PC. The combination of both classes of data for the same sample cohort might provide better criteria for identifying relevant factors involved in neoplasia. Here we describe transcriptional signatures identifying distinct normal and tumoral prostate tissue compartments, and the inference and demonstration of a new, highly recurrent copy number gain on chromosome 17q25.3. We have applied transcriptional profiling to tumoral and non-tumoral prostate samples with relatively homogeneous epithelial representations as well as pure stromal tissue from peripheral prostate and cultured cell lines, followed by quantitative RT-PCR validations and immunohistochemical analysis. In addition, we have performed in silico colocalization analysis of co-regulated genes and validation by fluorescent in situ hybridization (FISH). The transcriptomic analysis has allowed us to identify signatures corresponding to non-tumoral luminal and tumoral epithelium, basal epithelial cells, and prostate stromal tissue. In addition, in silico analysis of co-regulated expression of physically linked genes has allowed us to predict the occurrence of a copy number gain at chromosomal region 17q25.3. This computational inference was validated by fluorescent in situ hybridization, which showed gains in this region in over 65% of primary and metastatic tumoral samples. Our approach permits to directly link gene copy number variations with transcript co-regulation in association with neoplastic states. Therefore, transcriptomic studies of carefully selected samples can unveil new diagnostic markers and transcriptional signatures highly specific of PC, and lead to the discovery of novel genomic abnormalities that may provide additional insights into the causes and mechanisms
Co-regulation analysis of closely linked genes identifies a highly recurrent gain on chromosome 17q25.3 in prostate cancer
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Martínez-A Carlos
Full Text Available Abstract Background Transcriptional profiling of prostate cancer (PC has unveiled new markers of neoplasia and allowed insights into mechanisms underlying this disease. Genomewide analyses have also identified new chromosomal abnormalities associated with PC. The combination of both classes of data for the same sample cohort might provide better criteria for identifying relevant factors involved in neoplasia. Here we describe transcriptional signatures identifying distinct normal and tumoral prostate tissue compartments, and the inference and demonstration of a new, highly recurrent copy number gain on chromosome 17q25.3. Methods We have applied transcriptional profiling to tumoral and non-tumoral prostate samples with relatively homogeneous epithelial representations as well as pure stromal tissue from peripheral prostate and cultured cell lines, followed by quantitative RT-PCR validations and immunohistochemical analysis. In addition, we have performed in silico colocalization analysis of co-regulated genes and validation by fluorescent in situ hybridization (FISH. Results The transcriptomic analysis has allowed us to identify signatures corresponding to non-tumoral luminal and tumoral epithelium, basal epithelial cells, and prostate stromal tissue. In addition, in silico analysis of co-regulated expression of physically linked genes has allowed us to predict the occurrence of a copy number gain at chromosomal region 17q25.3. This computational inference was validated by fluorescent in situ hybridization, which showed gains in this region in over 65% of primary and metastatic tumoral samples. Conclusion Our approach permits to directly link gene copy number variations with transcript co-regulation in association with neoplastic states. Therefore, transcriptomic studies of carefully selected samples can unveil new diagnostic markers and transcriptional signatures highly specific of PC, and lead to the discovery of novel genomic abnormalities
Spatially resolving a starburst galaxy at hard X-ray energies: NuSTAR, CHANDRA, AND VLBA observations of NGC 253
DEFF Research Database (Denmark)
Wik, D. R.; Lehmer, B. D.; Hornschemeier, A. E.;
intermediate state black hole X-ray binaries. The global X-ray emission of the galaxy-dominated by the off-nuclear ULX and nuclear sources, which are also likely ULXs-falls steeply (photon index ≳ 3) above 10 keV, consistent with other NuSTAR-observed ULXs, and no significant excess above the background is...... the first time. As a follow up to our initial study of its nuclear region, we present the first results concerning the full galaxy from simultaneous NuSTAR, Chandra, and Very Long Baseline Array monitoring of the local starburst galaxy NGC 253. Above ~10 keV, nearly all the emission is concentrated...... within 100" of the galactic center, produced almost exclusively by three nuclear sources, an off-nuclear ultraluminous X-ray source (ULX), and a pulsar candidate that we identify for the first time in these observations. We detect 21 distinct sources in energy bands up to 25 keV, mostly consisting of...
Patients with high-bone-mass phenotype owing to Lrp5-T253I mutation have low plasma levels of serotonin
DEFF Research Database (Denmark)
Frost, Morten; Andersen, Tom E.; Yadav, Vijay;
The Lrp5 gene is a major determinant of bone mass accrual. It has been demonstrated recently to achieve this function by hampering the synthesis of gut-derived serotonin, which is a powerful inhibitor of bone formation. In this study we analyzed plasma serotonin levels in patients with a high......-bone-mass (HBM) phenotype owing to gain-of-function mutation of Lrp5 (T253I). A total of 9 HBM patients were compared with 18 sex- and age-matched controls. In HBM patients, the serotonin concentrations in platelet-poor plasma were significantly lower than in the controls (mean +/- SEM: 2.16 +/- 0.28 ng....../mL versus 3.51 +/- 0.49 ng/mL, respectively, p < .05). Our data support the hypothesis that circulating serotonin levels mediate the increased bone mass resulting from gain-of-function mutations in Lrp5 in humans. (c) 2010 American Society for Bone and Mineral Research....
VLA Detection of RRLs from the radio nucleus of NGC 253 Ionization by a weak AGN, an obscured SSC or a compact SNR ?
Mohan, N R; Goss, W M; Mohan, Niruj R.
We have imaged the H92alpha and H75alpha radio recombination line (RRL) emissions from the starburst galaxy NGC 253 with a resolution of ~4 pc. The peak of the RRL emission at both frequencies coincides with the unresolved radio nucleus. Both lines observed towards the nucleus are extremely wide, with FWHM of ~200 km /s. Modeling the RRL and radio continuum data for the radio nucleus shows that the lines arise in gas whose density is ~10^4 \\cc and mass is few thousand Msun, which requires an ionizing flux of (6-20)x10^{51} photons /s. We consider a SNR expanding in a dense medium, a star cluster and also an AGN as potential ionizing sources. Based on dynamical arguments, we rule out an SNR as a viable ionizing source. A star cluster model was considered and the dynamics of the ionized gas in a stellar-wind driven structure was investigated. Such a model is consistent with the properties of the ionized gas only for a cluster younger than ~10^5 years. The existence of such a young cluster at the nucleus seems i...
Etiology of hand, foot and mouth disease in 253 children in Huizhou during the period of 2009 to 2011%2009-2011年惠州市253例手足口病患儿病原学分析
Institute of Scientific and Technical Information of China (English)
刘燕; 方巧云; 严宇斌; 曾健君; 杨剑英
Objective To investigate the pathogens and prevalence of hand-foot-mouth disease (HFMD) in Huizhou during 2009 to 2011.Methods 253 specimens were collected from the children with HFMD and then were detected using fluorescence quantitative PCR.Some samples with positive results were typed by gene sequencing.Results 156 of 253 samples were PE positive.41 of the 156 samples were CoxA16 and 92 were EV71.CoxA16 (69%) was the major pathogen in 2009,while EV71 was prevalent in 2010 and 2011 (78.1% and 67.5%,respectively).The types of EV71 were EV71-C4a for 30 and ECHO3 for 2.The positive rate of intestinal virus accounted for 93.5% (146/156) in children aged less than 6 and was 73.0%(114/156) in those aged less than 3.Conclusions CoxA16 is the major pathogen for hand-food-mouth disease in 2009 and EV71 is the predominant pathogen in 2010 and 2011.EV71-C4a is the main type of EV71 in the past three years in Huizhou.Children younger than 3 are at high risk for EV71 infection.Prevention and control of hand-foot-mouth disease in summer and fall is a necessity.%目的 了解2009-2011年惠州市手足口病流行的病原及流行情况.方法 采集253份2009-2011年手足口病患儿的标本,采用荧光定量PCR法对患者标本进行核酸检测,对部分结果阳性的样品进行基因序列分型.结果 253份样品中,总肠道病毒核酸(PE)检测阳性156份,其中CoxA16核酸阳性41份,EV71核酸阳性92份;2009年手足口病流行的病原以CoxA16型为主(69.0%);2010年和2011年均以EV71型为主(分别为78.1%和67.5%);30份EV71型病毒的基因测序分型均为EV71-C4a型,2例EV阳性病例标本的病原基因型为ECHO3型;肠道病毒阳性率6岁以下儿童占阳性病例的93.5% (146/156),3岁以下幼童占阳性病例的73.0% (114/156).结论 本地区2009年手足口病流行的病原以CoxA16型为主,2010年和2011年以EV71型为主,3年流行的EV71病原基因型主要为EV71-C4a型,在其它肠道病毒阳性�
Osteoclasts from patients with autosomal dominant osteopetrosis type I caused by a T253I mutation in low-density lipoprotein receptor-related protein 5 are normal in vitro, but have decreased resorption capacity in vivo
DEFF Research Database (Denmark)
Henriksen, Kim; Gram, Jeppe; Høegh-Andersen, Pernille;
Autosomal dominant osteopetrosis type I (ADOI) is presumably caused by gain-of-function mutations in the LRP5 gene. Patients with a T253I mutation in LRP5 have a high bone mass phenotype, characterized by increased mineralizing surface index but abnormally low numbers of small osteoclasts....... To investigate the effect of the T253I mutation in LRP5 on osteoclasts, we isolated CD14+ monocytes from ADOI patients and assessed their ability to generate osteoclasts when treated with RANKL and M-CSF compared to that of age- and sex-matched control osteoclasts. We found normal osteoclastogenesis, expression...... of osteoclast markers, morphology, and localization of proteins involved in bone resorption, such as ClC-7 and cathepsin K. The ability to resorb bone was also normal. In vivo, we compared the bone resorption and bone formation response to T3 in ADOI patients and age- and sex-matched controls. We found...
Erratum to "Solar Sources and Geospace Consequences of Interplanetary Magnetic Clouds Observed During Solar Cycle 23-Paper 1" [J. Atmos. Sol.-Terr. Phys. 70(2-4) (2008) 245-253
Gopalswamy, N.; Akiyama, S.; Yashiro, S.; Michalek, G.; Lepping, R. P.
One of the figures (Fig. 4) in "Solar sources and geospace consequences of interplanetary magnetic Clouds observed during solar cycle 23 -- Paper 1" by Gopalswamy et al. (2008, JASTP, Vol. 70, Issues 2-4, February 2008, pp. 245-253) is incorrect because of a software error in t he routine that was used to make the plot. The source positions of various magnetic cloud (MC) types are therefore not plotted correctly.
Kinetics of the gas-phase reactions of chlorine atoms with CH2F2, CH3CCl3 and CF3CFH2 over the temperature range 253 – 551 K
DEFF Research Database (Denmark)
Nilsson, Elna Johanna Kristina; Johnson, Matthew Stanley; Nielsen, Ole John;
Relative rate techniques were used to study the title reactions in 930–1200 mbar of N2 diluent. The reaction rate coefficients measured in the present work are summarized by the expressions k(Cl+CH2F2) = 1.19×10-17 T 2 exp(-1023/T ) cm3 molecule-1 s-1 (253– 553 K), k(Cl+CH3CCl3) = 2.41×10-12 exp(...
2.53 kW all-fiberized superfluorescent fiber source based on a compact single-stage power-scaling scheme
Xu, Jiangming; Xiao, Hu; Leng, Jinyong; Zhang, Hanwei; Zhou, Pu; Chen, Jinbao
In this paper we demonstrate an all-fiberized superfluorescent fiber source that has a maximal output power of 2.53 kW and is based on a single-stage power amplification configuration. The seed source is a broadband-amplified spontaneous emission source with a full output power of 27.6 W. A single-stage dual-clad fiber amplifier is used, in which the maximal optical-to-optical conversion efficiency is 81.47%. A beam quality of M 2 = 1.53 is measured at an output power of 1 kW. At maximum output power, the central wavelength and full width at half maximum linewidth of the amplified light are 1082.08 nm and 6.32 nm, respectively. No conspicuous spike was observed at the stimulated Raman scattering wavelength. The corresponding power fluctuation is 2.97%, which indicates the good power stability of the broadband high-power superfluorescent fiber source (SFS) system. This kilowatt-class high-power all-fiberized SFS system which has high conversion efficiency and good power stability and is based on a compact single-stage power-scaling scheme, is an alternative and competitive solution for industrial precision processes and special stabilized pumping. To the best of our knowledge, this is the highest power SFS ever reported, and the first demonstration of a high-power SFS with a kW-level output power in a compact single-stage power-scaling scheme.
Cloning, Prokaryotic Expression, and Functional Testing of a γ-Gliadin Gene from Wheat Cultivar Shaan 253%小麦品种陕253γ-醇溶蛋白基因的克隆、原核表达与功能鉴定
Institute of Scientific and Technical Information of China (English)
王明霞; 高翔; 陈其皎; 董剑; 赵万春; 李艳亮; 李敏
The γ-gliadin gene (GenBank accession No.GQ857626) was isolated from a wheat (Triticum aestivum) cultivar with a hight quality Shaan 253, using inductuion a set of genome specific primers.The deduced amino acid sequence of GQ857626 exhibited an additional cysteine residue in the region Ⅱ of mature γ-gliadin subunits compared to the previous report.A prokaryotic expression vector was constructed to express GQ857626 in the host bacterium Escherichia coli Rosetta-gami B (DE3).The SDS-PAGE and Western blot analysis confirmed that the fusion protein was expressed by induction of 0.1 mmol L-1 isopropyl-β-D-thiogalactoside (IPTG), and its actual molecular weight was about 50 kD nearly equal to the predicted.After separation and purification using HisTrap HP affinity chromatography, the function of fusion protein was tested by means of micro 4 g farinograph.When the subunit of GQ857626 was integrated into the control flour through oxidation-reduction reaction, many important farinograph parameters changed drastically, such as development time, dough stabilizing time, degree of softening.Although the gluten strength of the control flour could be improved in some degree, the subunit of GQ857626 showed a negative effect on the rheological properties of wheat flour.%利用设计合成的特异γ-醇溶蛋白基因引物,采用PCR方法从小麦品种陕253克隆获得一个γ-醇溶蛋白基因(GenBank登录号为GQ857626).序列分析表明,该基因编码产物的Ⅱ区由于碱基转换产生一个额外的半胱氨酸残基.构建了GQ857626的原核表达载体并转入表达菌株E.coli Rosetta gami B(DE3),IPTG诱导其成功表达.使用HisTrap HP组氨酸标记亲和层析柱纯化该基因的表达产物,并使用4 g粉质仪分析其功能.结果显示,将此纯化蛋白通过氧化还原反应整合到基础面粉后,面团的形成时间缩短,稳定时间减少,弱化度增加,导致主要的粉质指数明显下降,说明该亚基对�
乌鲁木齐市253例孕妇叶酸、锌相关知识认知度及服用情况调查%Survey of nutrition knowledge and usage of folic acid and zinc in 253 pregnant women from Urumqi
Institute of Scientific and Technical Information of China (English)
马晶; 吐尔逊江·买买提明; 阿依加玛丽·王; 王晓军; 迪丽霍玛尔·吾尔开希
Objective To investigate pregnant women′s knowledge and usage of folic acid and zinc in Uru-mqi area,and to find out the possible influencing factors.Methods 253 pregnant women in Maternal and Child Health Hospital of Urumqi were investigated by questionnaire survey.The collected data were ana-lyzed the rate of awareness and usage by univariate analysis method and we made a comparison between the differences in age,education level,household income and occupation.Results The average rate of nutri-tion awareness of folic acid and zinc was 83.4% and 58.1%.The intake rate was 80.2% and 23.3%;the fo-lic acid knowledge and usage were significant different in different ages,educational levels,occupation (P<0.05).The awareness and usage of folic acid and zinc was lower in pregnant women from low-income, poor education backgrounds than that in those from high-income,good education environment (P <0.05). One of the main sources of pregnant women′s folic acid and zinc knowledge comes from doctors′guidance, accounting for 42.5% and 42.2%;next from the media,accounting for 27.6% and 27.7%;medical books accounting for 21% and 22.5%;birth planning workers and expert lectures accounted for the least,8.8%and 7.7%.Conclusion The rates of awareness and intake of folic acid has incresed in pregnant women in Urumqi.However,the rates of awareness and intake of zinc was very low.Therefore,we should increase the efforts in the education of nutrition knowledge of folic acid,zinc among the pregnant women of low ed-ucation level, low age and low-income so as to promote maternal and child health and reduce maternal complications.%目的:了解乌鲁木齐市孕妇叶酸及锌相关知识的认知度和服用情况,探讨其可能的影响因素,为加强孕妇营养及进行健康教育提供科学依据。方法采用自行编制的问卷对新疆维吾尔自治区妇幼保健中心就诊的253名孕妇进行调查。对孕妇叶酸、锌相关知识的知晓及服用情况进�
Reseña: Seguridad ciudadana: visiones compartidas, de José Luis Estrada Rodríguez (coord., Universidad Autónoma del Estado de México, Instituto de Administración Pública del Estado de México, 2014, 253 pp. ISBN: 978-607-8087-19-8
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Delia Gutiérrez Linares
Full Text Available Reseña: Seguridad ciudadana: visiones compartidas, de José Luis Estrada Rodríguez (coord., Universidad Autónoma del Estado de México, Instituto de Administración Pública del Estado de México, 2014, 253 pp. ISBN: 978-607-8087-19-8
关中地区'陕253'品质与氮、磷、钾配比间关系的研究%Relationship of the Quality with Nitrogen, Phosphorous and Potassium Ratio in the Wheat Variety 'Shaan 253'
Institute of Scientific and Technical Information of China (English)
裴阿卫; 张睿; 刘党校; 赵永; 王新中
选用强筋小麦品种'陕253',在关中东、西和中部采取不同的氮(N)、磷(P)、钾(K)肥配比处理,用GGE Biplot叠图软件分析肥料配比对不同地区籽粒品质性状的效应.研究结果表明:不同N、P、K配比对强筋小麦品质性状的效应与生态区有关.关中西部蛋白质含量、容重、硬度、稳定时间之间呈显著正相关,蛋白质含量、容重和硬度的最优N、P、K配比是N 135 kg/hm2、P2O5 225 kg/hm2、K2O 120 kg/hm2,降落值、出粉率、湿面筋含量和稳定时间是N 225 kg/hm2、P2O5 225 kg/hm2、K2O 120 kg/hm2;关中中部蛋白质含量、稳定时间、沉淀值、容重之间呈显著正相关,其最优N、P、K配比为N 225 kg/hm2、P2O5 225 kg/hm2、K2O 120 kg/hm2,降落值和吸水率最优N、P、K配比为N 135 kg/hm2、P2O5 225 kg/hm2、K2O 180 kg/hm2;关中东部籽粒蛋白质含量与吸水率之间显著正相关,其最优N、P、K配比为N 225 kg/hm2、P2O5 225 kg/hm2、K2O 180 kg/hm2,湿面筋含量、降落值、沉淀值、容重、出粉率和硬度间表现极限著的正相关关系,最优N、P、K配比是N 135 kg/hm2、P2O5 120 kg/hm2、K2O 120 kg/hm2.
Interstitial deletion of chromosome 1q [del(1)(q24q25.3)] identified by fluorescence in situ hybridization and gene dosage analysis of apolipoprotein A-II, coagulation factor V, and antithrombin III
Energy Technology Data Exchange (ETDEWEB)
Takano, Takako; Yamanouchi, Yasuko; Mori, Yosuke [Teikyo Univ. School of Medicine, Tokyo (Japan)] [and others
We report on a 12-month-old Japanese boy with an interstitial deletion of the long-arm of chromosome 1 and meningomyelocele, hydrocephalus, anal atresia, atrial septal defect, left renal agenesis, bilateral cryptorchidism, talipes equinovarus, low birth weight, growth/developmental retardation, and many minor anomalies. By conventional GTG-banding, his karyotype was first interpreted as 46,XY,de1(1)(q23q24), but it was corrected as 46,XY.ish del(1)(q24q25.3) by fluorescence in situ hybridization using 11 known cosmid clones as probes. His serum levels of apolipoprotein A-II (gene symbol: APOA2, previously assigned to 1q21-q23) and coagulation factor V (F5, 1q21-q25) were normal, while serum concentration and activity of antithrombin III (AT3, 1q23-q25.1) was low. The results indicated that localization of APOA2 and F5 are proximal to the deleted region and AT3 is located within the deletion extent in the patient. 16 refs., 4 figs.
A conservative assessment of the major genetic causes of idiopathic chronic pancreatitis: data from a comprehensive analysis of PRSS1, SPINK1, CTRC and CFTR genes in 253 young French patients.
Directory of Open Access Journals (Sweden)
Emmanuelle Masson
Full Text Available Idiopathic chronic pancreatitis (ICP has traditionally been defined as chronic pancreatitis in the absence of any obvious precipitating factors (e.g. alcohol abuse and family history of the disease. Studies over the past 15 years have revealed that ICP has a highly complex genetic architecture involving multiple gene loci. Here, we have attempted to provide a conservative assessment of the major genetic causes of ICP in a sample of 253 young French ICP patients. For the first time, conventional types of mutation (comprising coding sequence variants and variants at intron/exon boundaries and gross genomic rearrangements were screened for in all four major pancreatitis genes, PRSS1, SPINK1, CTRC and CFTR. For the purposes of the study, synonymous, intronic and 5'- or 3'-untranslated region variants were excluded from the analysis except where there was persuasive evidence of functional consequences. The remaining sequence variants/genotypes were classified into causative, contributory or neutral categories by consideration of (i their allele frequencies in patient and normal control populations, (ii their presumed or experimentally confirmed functional effects, (iii the relative importance of their associated genes in the pathogenesis of chronic pancreatitis and (iv gene-gene interactions wherever applicable. Adoption of this strategy allowed us to assess the pathogenic relevance of specific variants/genotypes to their respective carriers to an unprecedented degree. The genetic cause of ICP could be assigned in 23.7% of individuals in the study group. A strong genetic susceptibility factor was also present in an additional 24.5% of cases. Taken together, up to 48.2% of the studied ICP patients were found to display evidence of a genetic basis for their pancreatitis. Whereas these particular proportions may not be extrapolable to all ICP patients, the approach employed should serve as a useful framework for acquiring a better understanding of the
... or maintenance. Security documents mean all collateral securing the U.S. note's repayment and all... best use harvests of that or any other species. U.S. means the United States of America and,...
... opinion, or because of fear of torture is eligible to apply for asylum or withholding of removal under 8 CFR part 208. Service officers shall take particular care to ensure that the provisions of § 208.5(b... 235(c) alleging persecution or torture. Any alien crewman, stowaway, or alien removable under...
... under the SAFETY Act, except the authority to declare that an act is an Act of Terrorism for purposes of section 865(2) of the SAFETY Act, may be exercised by the Under Secretary for Science and Technology of... DEPARTMENT OF HOMELAND SECURITY, OFFICE OF THE SECRETARY REGULATIONS TO SUPPORT ANTI-TERRORISM BY...
50 CFR 216.253 - Prohibitions.
..., DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE MAMMALS Taking Marine Mammals Incidental to Conducting Precision Strike Weapon Missions in the Gulf of Mexico §...
42 CFR 447.253 - Other requirements.
... acquisition by the seller to the date of the change of ownership) in the Consumer Price Index for All Urban... services through the use of rates that are reasonable and adequate to meet the costs that must be incurred... index applied in the aggregate with respect to those facilities that have undergone a change...
Associations of chromosomes 17q22, 10q25.3 and ABCA4 gene polymorphisms with non-syndromic cleft lip/palate in Ningxia Hui and Han population%宁夏回汉族人群中染色体17q22、10q25.3和ABCA4基因多态性与非综合征型唇腭裂的关联
Institute of Scientific and Technical Information of China (English)
周忠伟; 杨雄; 万应彪; 信燕华; 翟堃; 马坚; 黄永清; 姜敏; 王怡瑞
目的 研究中国宁夏地区回汉族人群染色体17q22(rs227731)、ABCA4(rs560426)和10q25.3(7078160)位点单核苷酸多态性与非综合征型唇腭裂的相关性.方法 研究对象包括非综合征型唇腭裂患儿415例,其中汉族191例,回族224例;患儿父亲205例,母亲240例;其中完整3人核心家系158个.将他们分为单纯唇裂组、单纯腭裂组、唇腭裂组,单纯唇裂组与唇腭裂组合并为唇裂伴或不伴腭裂组;对照组为健康大学生385例,其中汉族281例,回族104例.采用TaqMan基因型鉴定技术检测3个单核苷酸多态位点的基因型,进行病例对照分析、传递不平衡检验、以家系为基础的相关性分析.结果 ①染色体17q22区段的rs227731位点在汉族单纯唇裂组等位基因频率与对照组比较存在统计学差异(P<0.05),在唇裂伴或不伴腭裂组中等位基因频率与对照组比较存在统计学差异(P<0.05).回汉族唇腭裂组等位基因频率和唇裂伴或不伴腭裂组基因型、等位基因频率比较均存在统计学差异(P=0.04,P=0.04,P=0.01);②ABCA4基因的rs560426位点在汉族单纯唇裂组基因型与等位基因频率与对照组比较存在统计学差异(P<0.05),在唇裂伴或不伴腭裂组中基因型与等位基因频率与对照组比较存在统计学差异(P<0.05),回汉族单纯唇裂组基因型、等位基因比较存在统计学差异(P=0.04,P=0.01);③染色体10q25.3区段的rs7078160位点基因型与等位基因频率与对照组比较及回汉族相互比较均无统计学差异(P<0.05).结论 在宁夏汉族人群中染色体17q22区段的rs227731位点和ABCA4基因的rs560426位点单核苷酸多态性与非综合征型唇腭裂有统计学关联,染色体10q25.3区段的rs7078160位点与非综合征型唇腭裂无统计学关联.%Objective To explore if genetic variation in chromosome 17q22 (rs22731), ABCA4 (rs560426) and 10q25. 3(rs7078160)genes contributes to non-syndromic cleft lip
19 CFR 10.253 - Articles eligible for preferential treatment.
...) Footwear not designated on December 4, 1991, as eligible articles for the purpose of the Generalized System... and equipment which are allocable to the specific merchandise; (C) Research, development,...
7 CFR 253.7 - Certification of households.
... determine an amount to be used for certification purposes based on the best available information. Reasons... responsibility for providing documentary evidence or an acceptable collateral contact to support its income... proves the statements on the application. The State agency shall also accept verification from...
40 CFR 180.253 - Methomyl; tolerances for residues.
... million Alfalfa, forage 10 Alfalfa, hay 10 Apple 1 Asparagus 2 Avocado 2 Barley, grain 1 Barley, hay 10 Barley, straw 10 Bean, dry, seed 0.1(N) Bean, forage 10 Bean, succulent 2 Beet, garden, tops 6... Corn, sweet, kernel plus cob with husks removed 0.1(N) Corn, sweet, stover 10 Cotton, undelinted seed...
40 CFR 25.3 - Policy and objectives.
... UNDER THE RESOURCE CONSERVATION AND RECOVERY ACT, THE SAFE DRINKING WATER ACT, AND THE CLEAN WATER ACT... interested and affected parties to communicate their views. Public participation includes providing access to... resources and access to decision-making may be relatively limited. (c) The following are the objectives...
Lifescience Database Archive (English)
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Lifescience Database Archive (English)
Full Text Available 410884 |AJ410884.1 Influenza A virus (swine/Cotes d'Armor/1515/99 (H1N1)) partial N1NA gene for Neuraminidas...e, genomic RNA. 42 1.1 2 AJ410883 |AJ410883.1 Influenza A virus (swine/Cotes d'Armor/1482/99 (H1N1
7 CFR 253.5 - State agency requirements.
...-income households on the reservation are a single language minority. Single-language minority refers to households which speak the same non-English language and which do not contain adults(s) fluent in English as a second language. If the non-English language is spoken but not written, the State agency...
Lifescience Database Archive (English)
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7 CFR 253.6 - Eligibility of households.
... disability benefits; worker's or unemployment compensation; old-age, survivors, or social security benefits... month received unless specifically excluded from consideration as a resource by other Federal law. (ix... grandparents, and others) and title III (SCORE and ACE) of the Domestic Volunteer Services Act of 1973 (Pub....
Lifescience Database Archive (English)
Full Text Available mRNA, complete cds. 151 2e-33 1 CK273320 |CK273320.1 EST719398 potato abiotic stress cDNA library Solanum tu...berosum cDNA clone POADA55 5' end, mRNA sequence. 72 2e-09 1 CK265485 |CK265485.1 EST711563 potato abiotic s... 2e-09 1 CK273321 |CK273321.1 EST719399 potato abiotic stress cDNA library Solanum tuberosum cDNA clone POAD
Lifescience Database Archive (English)
Full Text Available red pieces. 36 0.22 7 BI435853 |BI435853.1 EST538614 P. infestans-challenged potato leaf, compatible reactio...1390 |BG591390.1 EST499232 P. infestans-challenged leaf Solanum tuberosum cDNA clone BPLI8D17 5' sequence, m...CF59 3' end, mRNA sequence. 48 0.31 1 BI435340 |BI435340.1 EST538101 P. infestans-challenged leaf Solanum tu
Lifescience Database Archive (English)
Full Text Available 5 |AW705505.1 sk49h12.y1 Gm-c1019 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1019-5952 5', mRNA seq...uence. 46 0.46 1 AI441512 |AI441512.1 sa87c11.y1 Gm-c1004 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm... Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1019-6819 5', mRNA sequence. 46 0.46 1 BI317694 |BI3176...94.1 saf19h09.y1 Gm-c1076 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1076-1506 5', mRNA sequence. 4
40 CFR 98.253 - Calculating GHG emissions.
... required under 40 CFR part 63 subpart UUU, assume %CO to be zero. (iii) If you have a CO boiler that uses... treatment incinerator) must be reported under subpart C of this part (General Stationary Fuel Combustion... feed (including sour water stripper gas) to the sulfur recovery plant (scf/year). 44 = Molecular...
37 CFR 253.10 - Cost of living adjustment.
... determined by the Consumer Price Index (all consumers, all items) during the period from the most recent Index published prior to December 1, 2002, to the most recent Index published prior to December 1, 2003... COPYRIGHT ARBITRATION ROYALTY PANEL RULES AND PROCEDURES USE OF CERTAIN COPYRIGHTED WORKS IN CONNECTION...
20 CFR 632.253 - Special operating provisions.
... Special operating provisions. Native American grantees shall: (a) Provide services to youths most in need...: vocational exposure, counseling, testing, resume preparation, job interview preparation, providing labor... to develop cooperative relationships with other community resources so that these activities...
Lifescience Database Archive (English)
Full Text Available CAAAAATTCAAGACAAAGAAGGTA TNCCA sequence update 2001. 6. 1 Translated Amino Acid sequence ---*xxxsxkxrxppxxxvsfsxvxixkmxxlslipkskknxls...QIFVKTLTGKTITLEVEGSDNIENVKTKIQDKEGX P Translated Amino Acid sequence (All Frames) Frame A: ---*xxxsxkxrxppxxxvsfsxvxixkmxxls...e C: ---kxxfxkxkvspxsxxfifxgxhxknxgpfsdskiqkesxlhlssd*kvvckxlsxh* lvrpsllk*glr*y*kc*xkgsrqrryptrptkinfrw*tir...lipkskknxlstcpqikrwyanxcqxi nw*dhhx*SEGSDNIENVKXKVQDKEGIPPDQQRLIF
Lifescience Database Archive (English)
Full Text Available 3 Translated Amino Acid sequence fllyky*ihilffyil*HFIKKKKKKKFKXXPFXKKK--- ---GKXXLXNVKTXXQDKEGXPPDQQRXISLVNN*xmxxlslitiskknxls...ikfifyffiycnis*kkkkkknlkxxlfxkkk--- ---GKXXLXNVKTXXQDKEGXPPDQQRXISLVNN*xmxxlslitiskknxlstwssd*ex vckslskh*lv
Use of trioctylphosphine oxide for transplutonium element extraction and purification
International Nuclear Information System (INIS)
Investigated was extraction of tri-valent curium, berkelium, californium, einsteinium as well as cerium and europium with trioctylphosphin oxide from lactic acid solutions, containing DTPA and aluminium nitrate depending on the aluminium nitrate and TOPO concentrations and nitric acid solutions of variable concentration as well. Under optimum conditions of extraction chromatography of berkelium studied was the distribution of cobalt, nickel, chromium, iron, aluminium, titanium, zirconium and niobium ions, and the coefficients of berkelium purification from cations investigated were determined. The effect of weight quantities of cation impurities on extraction chromatographic yield of berkelium has been investigated. Examples of practice application of the extraction chromatography with the use of TOPO are given
Extraction studies of selected actinide ions from aqueous solutions with 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione and tri-n-octylphosphine oxide
Energy Technology Data Exchange (ETDEWEB)
Hannink, N.J.; Hoffman, D.C. [Lawrence Berkeley Lab., CA (United States)]|[California Univ., Berkeley, CA (United States). Dept. of Chemistry; Smith, B.F. [Los Alamos National Lab., NM (United States)
The first measurements of distribution coefficients (K{sub d}) for Cm(III), Bk(III), Cf(III), Es(III), and Fm(III) between aqueous perchlorate solutions and solutions of 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT) and the synergist tri-n-octylphosphine oxide (TOPO) in toluene are reported. Curium-243, berkelium-250, californium-249, einsteinium-254, and fermium-253 were used in these studies. The K{sub d} for {sup 241}Am was also measured and is in agreement with previously published results. Our new results show that the K{sub d}`s decrease gradually with increasing atomic number for the actinides with a dip at Cf. In general, the K{sub d}`s for these actinides are about a factor of 5 to 10 greater than the K{sub d}`s for the homologous lanthanides at a pH of 2.9, a BMPPT concentration of 0.2 M, and a TOPO concentration of 0.04 M. The larger K{sub d}`s for the actinides are consistent with greater covalent bonding between the actinide metal ion and the sulfur bonding site in the ligand.
Extraction studies of selected actinide ions from aqueous solutions with 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione and tri-n-octylphosphine oxide
Energy Technology Data Exchange (ETDEWEB)
Hannink, N.J.; Hoffman, D.C. (Lawrence Berkeley Lab., CA (United States) California Univ., Berkeley, CA (United States). Dept. of Chemistry); Smith, B.F. (Los Alamos National Lab., NM (United States))
The first measurements of distribution coefficients (K{sub d}) for Cm(III), Bk(III), Cf(III), Es(III), and Fm(III) between aqueous perchlorate solutions and solutions of 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT) and the synergist tri-n-octylphosphine oxide (TOPO) in toluene are reported. Curium-243, berkelium-250, californium-249, einsteinium-254, and fermium-253 were used in these studies. The K{sub d} for {sup 241}Am was also measured and is in agreement with previously published results. Our new results show that the K{sub d}'s decrease gradually with increasing atomic number for the actinides with a dip at Cf. In general, the K{sub d}'s for these actinides are about a factor of 5 to 10 greater than the K{sub d}'s for the homologous lanthanides at a pH of 2.9, a BMPPT concentration of 0.2 M, and a TOPO concentration of 0.04 M. The larger K{sub d}'s for the actinides are consistent with greater covalent bonding between the actinide metal ion and the sulfur bonding site in the ligand.
Extraction studies of selected actinide ions from aqueous solutions with 4-benzoyl-2,4-Dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione and Tri-n-octylphosphine oxide
Energy Technology Data Exchange (ETDEWEB)
Hannink, N.J.; Hoffman, D.C. [Lawrence Berkeley Lab., CA (United States); Smith, B.F. [Los Alamos National Lab., NM (United States)
The first measurements of distribution coefficients (k{sub d}) for Cm(III), Bk(III), Cf(III), Es(III), and Fm(III) between aqueous perchlorate solutions and solutions of 4-benzoyl-2,4-dihydro-5-methyl-2-phenyl-3H-pyrazol-3-thione (BMPPT) and the synergist tri-n-octylphosphine oxide (TOPO) in toluene are reported. Curium-243, berkelium-250, californium-249, einsteinium-254, and fermium-253 were used in these studies. The K{sub d} for {sup 241}Am was also measured and is in agreement with previously published results. Our new results show that the K{sub d}`s decrease gradually with increasing atomic number for the actinides with a dip at Cf. In general, the K{sub d}`s for these actinides are about about a factor of 10 greater than the K{sub d}`s for the homologous lanthanides at a pH of 2.9, a BMPPT concentration of 0.2 M, and a TOPO concentration of 0.04 M. The larger K{sub d}`s for the actinides are consistent with greater covalent bonding between the actinide metal ion and the sulfur bonding site in the ligand. 9 refs., 2 figs., 1 tab.
30 CFR 253.3 - How are the terms used in this regulation defined?
... may be presented, according to 33 CFR part 136, subpart D. Bay means a body of water included in the.... Coastline means the line of ordinary low water along that portion of the coast that is in direct contact...) Seaward of the coastline; or (ii) In any portion of a bay that is: (A) Connected to the sea,...
29 CFR 1910.253 - Oxygen-fuel gas welding and cutting.
... accordance with the regulations of the U.S. Department of Transportation, 49 CFR parts 171-179. (ii... reach them, or fire-resistant shields shall be provided. (J) Cylinders shall not be placed where they...) Joints in brass or copper pipe shall be welded, brazed, threaded, or flanged. If of the socket type,...
40 CFR 52.253 - Metal surface coating thinner and reducer.
... described in 40 CFR part 81, dated July 1, 1979, except as follows: (1) In the following portions of the... 40 Protection of Environment 3 2010-07-01 2010-07-01 false Metal surface coating thinner and... coating thinner and reducer. (a) All terms defined in § 52.254 are used herein with the meanings...
SU-E-J-253: The Radiomics Toolbox in the Computational Environment for Radiological Research (CERR)
Energy Technology Data Exchange (ETDEWEB)
Apte, A; Veeraraghavan, H; Oh, J; Kijewski, P; Deasy, J [Memorial Sloan Kettering Cancer Center, New York, NY (United States)
Purpose: To present an open source and free platform to facilitate radiomics research — The "Radiomics toolbox" in CERR. Method: There is scarcity of open source tools that support end-to-end modeling of image features to predict patient outcomes. The "Radiomics toolbox" strives to fill the need for such a software platform. The platform supports (1) import of various kinds of image modalities like CT, PET, MR, SPECT, US. (2) Contouring tools to delineate structures of interest. (3) Extraction and storage of image based features like 1st order statistics, gray-scale co-occurrence and zonesize matrix based texture features and shape features and (4) Statistical Analysis. Statistical analysis of the extracted features is supported with basic functionality that includes univariate correlations, Kaplan-Meir curves and advanced functionality that includes feature reduction and multivariate modeling. The graphical user interface and the data management are performed with Matlab for the ease of development and readability of code and features for wide audience. Open-source software developed with other programming languages is integrated to enhance various components of this toolbox. For example: Java-based DCM4CHE for import of DICOM, R for statistical analysis. Results: The Radiomics toolbox will be distributed as an open source, GNU copyrighted software. The toolbox was prototyped for modeling Oropharyngeal PET dataset at MSKCC. The analysis will be presented in a separate paper. Conclusion: The Radiomics Toolbox provides an extensible platform for extracting and modeling image features. To emphasize new uses of CERR for radiomics and image-based research, we have changed the name from the "Computational Environment for Radiotherapy Research" to the "Computational Environment for Radiological Research".
7 CFR 2.53 - Administrator, Food Safety and Inspection Service.
.... 120). (8) Enter into contracts, grants, or cooperative agreements to further research programs in the... pertains to issuance of certificates of condition of live animals intended and offered for export (21 U.S.C... or her authority, exercise the functions delegated to the Secretary by Executive Order 12580, 3...
SU-E-J-253: The Radiomics Toolbox in the Computational Environment for Radiological Research (CERR)
International Nuclear Information System (INIS)
Purpose: To present an open source and free platform to facilitate radiomics research — The "Radiomics toolbox" in CERR. Method: There is scarcity of open source tools that support end-to-end modeling of image features to predict patient outcomes. The "Radiomics toolbox" strives to fill the need for such a software platform. The platform supports (1) import of various kinds of image modalities like CT, PET, MR, SPECT, US. (2) Contouring tools to delineate structures of interest. (3) Extraction and storage of image based features like 1st order statistics, gray-scale co-occurrence and zonesize matrix based texture features and shape features and (4) Statistical Analysis. Statistical analysis of the extracted features is supported with basic functionality that includes univariate correlations, Kaplan-Meir curves and advanced functionality that includes feature reduction and multivariate modeling. The graphical user interface and the data management are performed with Matlab for the ease of development and readability of code and features for wide audience. Open-source software developed with other programming languages is integrated to enhance various components of this toolbox. For example: Java-based DCM4CHE for import of DICOM, R for statistical analysis. Results: The Radiomics toolbox will be distributed as an open source, GNU copyrighted software. The toolbox was prototyped for modeling Oropharyngeal PET dataset at MSKCC. The analysis will be presented in a separate paper. Conclusion: The Radiomics Toolbox provides an extensible platform for extracting and modeling image features. To emphasize new uses of CERR for radiomics and image-based research, we have changed the name from the "Computational Environment for Radiotherapy Research" to the "Computational Environment for Radiological Research"
30 CFR Appendix to Part 253 - List of U.S. Geological Survey Topographic Maps
...; Crooked Point; Cross City SW; Crystal River; Destin; Dog Island; Dunedin; East Pass; Egmont Key; El Jobean...; Port Richey NE; Port Saint Joe; Port Tampa; Punta Gorda; Punta Gorda SE; Punta Gorda SW; Red Head; Red... Point; Deep Lake; Dixon Bay; Dog Lake; Door Point; East Bay Junop; Eastern Isles; Dernieres;...
37 CFR 253.6 - Performance of musical compositions by other public broadcasting entities.
... COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES AND PROCEDURES USE OF... established in this section, the rates and terms of any license agreements entered into by copyright owners... this section shall furnish to ASCAP, BMI and SESAC, upon request, a music-use report during one week...
253例青少年腰椎骨密度分析%Analysis of the bone mineral density of the lumbar vertebrae in adolescents:a report of 253 cases
Institute of Scientific and Technical Information of China (English)
周莉; 秦建平; 邹丽华; 肖新华
目的:了解青少年骨骼健康状况,探讨腰椎( L2-4)骨密度与性别、血清25-( OH) D3、体重指数、饮食习惯、体育锻炼、性发育早晚的关系。方法双能X线仪测定腰椎( L2-4)骨密度,应用Z值,半自动酶标法测定血清25-( OH) D3,饮食习惯、体育锻炼、性发育早晚均采用调查法,并分组,作方差及组间统计分析。结果 Z值≤-2.0者百分比为6%,男女组BMD及Z值无显著差异(P>0.05),Z值≤-2.0组的25-(OH)D3、体重指数较其他组低(P<0.01),素食厌食组的Z值较其他组低(P<0.01),有效运动量及性发育早晚不同的各组间Z值均有显著差异(P<0.01)。结论双能X线测定腰椎(L2-4)骨密度适合于评估青少年骨骼健康状况,骨密度Z值水平与血清25-( OH) D3、体重指数、饮食习惯、体育锻炼、性发育早晚等有关。%Objective To learn the bone health status in adolescents, and to explore the relationship between the bone mineral density (BMD) of the lumbar vertebrae (L2-4) and gender, serum 25-(OH)D3, body mass index (BMI), diet habit, physical exercise, and sexual developmental.Methods BMD of L2-4 was detected using dual energy X-ray absorptiometry (DEXA), and Z value was obtained.The serum concentration of 25-( OH) D3 was determined using semi-automatic enzyme immunoassay. The data of diet habit, physical exercise, and sexual developmental were acquired using survey method.Then all the subjects were divided into different groups.The difference between groups was statistical analyzed.Results Among all the subjects, 6%had a Z value≤--2.0.No significant difference of BMD and Z value between men and women was observed (P>0.05).The serum 25-(OH)D3 concentration and BMI in the group with Z value≤ -2.0 were lower than those in other groups (P<0.01).The Z value in vegetarian anorexia group was lower than that in other groups ( P<0.01 ) .The Z value in effective exercise amount and different sexual development groups showed significant difference (P<0.01).Conclusion The detection of L2-4 BMD using DEXA is suitable for the evaluation of bone health in adolescents.The Z value of BMD is correlated with the serum 25-( OH) D3 concentration, BMI, diet habit, physical exercise, and sexual development.
The importance of education in the promotion of organ donation - doi: 10.5020/18061230.2012.p253
Directory of Open Access Journals (Sweden)
Taise Ribeiro Morais
Full Text Available Transplantation and human organ donation are controversial issues that have generated much interest and discussion. The lack of clarification and the sensationalist news about organ trafficking contribute to raise questions and render the myths and prejudices permanent.The donation of organs and tissues is seen by society in general, as an act of solidarity and love from the family. However, it requires decision-making at a time of extreme pain and distress, caused by the impact of breaking news of death, the feeling of loss and the unexpected interruption of a life course(1.As the criteria of death are modified, the concept of brain death arises, along with the possibility of using donor organs and tissues. When there is not a good understanding of the organ donation process, the relatives of potential donors feel apprehensive, doubtful and undecided at the time of occurrence, because it is a subject about which there hasn't been much clarification(1.Brazil has the largest public transplants program in the world, since the government finances 92% of procedures done in the country. However, when we consider the rate of post mortem transplant into the population, Brazil's results are little expressive(2.Family refusal is a major obstacle to the realization of transplants, and is also identified as major cause for the shortage of organs and tissues for transplantation. Families who understand well the diagnosis of brain death are more favorable to organ donation, compared to families who believe that death only occurs after the heart stops. Therefore, the poor level of information, either by the quality of information concerning brain death, either by not having exceeded the barrier of stigmatized fear of organ trading, propagated by the media, drastically reduces the number of patients who are benefited from receiving an organ(3.Although all people are responsible for disseminating information, we must also educate health professionals, since they interfere directly in the likely donor's family decision. Perhaps, they lack the study of Thanatology. These professionals deal directly with death but do not investigate death, mourning. The family situation at the time of mourning, hardened by the difficult decision of donating the organs of their beloved one, should form a strong synergistic relationship, as it comes into question the shock of death and the decision to save other people's lives. It has also been disclosed that religion is considered one of the reasons to refuse the donation of organs and tissues for transplantation. It is, thus, necessary to give greater attention to people's religious beliefs and values by the time of the loss of their relatives. The literature is rich in references demonstrating that the mass media, despite their high national and global spreading power, are not best suited to provide sufficient explanation on such contentious issues as it is, among others, the organ donation. Instead, the means, the symbology and the repertoire often used by mass media cause more confusion than clarification(4.A study in Spain found that a lot of information spread in the media could be an alternative to the clarification of doubts, however, it sometimes reproduce misinformation, superficial and prejudice-based ideas, being unable to modify negative behavior related to organ donation.A research conducted with people attending health centers in Spain showed that only 7% of the respondents received information about transplantation from primary care professionals. Although the negative information has been quite absorbed, the study indicates that, even in small proportion, the positive information has generated a new way of interpreting organ donation(6We here emphasize the importance of discussing the issue "organ donation" with friends and family, because people, being well educated, are capable of promoting discussions, which that can be understood as promotion of donation.The profile of the opponent to organ donation is: man or woman over the age of 45 years, with low sc
37 CFR 253.4 - Performance of musical compositions by PBS, NPR and other public broadcasting entities engaged in...
... background or theme music in a PBS program: 2003-2007 $56.81 (3) For performance of such a work in a feature... music in a program of a station of PBS: 2003-2007 $4.04 (5) For the performance of such a work in a... theme music in an NPR program: 2003-2007 $5.51 (7) For the performance of such a work in a...
SU-E-T-253: Open-Source Automatic Software for Quantifying Biological Assays of Radiation Effects
Energy Technology Data Exchange (ETDEWEB)
Detappe, A [University of Lyon (France); Dana-Farber Cancer Institute, Boston, MA (United States); Korideck, H [Dana-Farber Cancer Institute, Boston, MA (United States); Makrigiorgos, G; Berbeco, R [Dana-Farber Cancer Institute, Boston, MA (United States); Brigham and Women' s Hospital, Boston, MA (United States)
Purpose: Clonogenic cell survival is a common assay for quantifying the effect of drugs and radiation. Manual counting of surviving colonies can take 30–90seconds per plate, a major limitation for large studies. Currently available automatic counting tools are not easily modified for radiation oncology research. Our goal is to provide an open-source toolkit for precise, accurate and fast analysis of biological assays in radiation oncology. Methods: As an example analysis, we used HeLa cells incubated with gadolinium nanoparticles prior to irradiation. After treatment, the cells are grown for 14days to allow for colony formation. To analyze the colony growth, we capture images of each dish for archiving and automatic computer-based analysis. A FujifilmX20 camera is placed at the top of a box setup, 20cm above the sample, which is backlit by a LED lamp placed at the bottom of the box. We use a Gaussian filter (width=1.3mm) and color threshold (19–255). The minimum size for a colony to be counted is 1mm. For this example, 20 dishes with a large range of colonies were analyzed. Each dish was counted 3 times manually by 3 different users and then compared to our counter. Results: Automatic counting of cell colonies takes an average of 7seconds, enabling the analysis process to be accelerated 4–12 times. The average precision of the automatic counter was 1.7%. The Student t-test demonstrated the non-significant differences between the two counting methods (p=0.64). The ICC demonstrated the reliability of each method with ICC>0.999 (automatic) and ICC=0.95 (manual). Conclusion: We developed an open-source automatic toolkit for the analysis of biological assays in radiation oncology and demonstrated the accuracy, precision and effort savings for clonogenic cell survival quantification. This toolkit is currently being used in two laboratories for routine experimental analysis and will be made freely available on our departmental website.
30 CFR 253.24 - When I submit audited annual financial statements to verify my net worth, what standards must...
... (GAAS) of the United States, or other international auditing standards that MMS determines to be equivalent. (c) The financial information you submit must be expressed in U.S. dollars. If this information... statements to verify my net worth, what standards must they meet? (a) Your audited annual...
40 CFR 421.253 - Effluent limitations guidelines representing the degree of effluent reduction attainable by the...
... achievable. Except as provided in 40 CFR 125.30 through 125.32, any existing point source subject to this... Silver 0.015 0.006 Zinc 0.051 0.021 Gold 0.005 (e) Calciner Wet Air Pollution Control. BAT Limitations... condensed Lead 4.928 2.288 Mercury 2.640 1.056 Silver 5.104 2.112 Zinc 17.950 7.392 Gold 1.760 (g)...
VANESSEN, AJ; KOK, K; van den Berg, Anke; DEJONG, B; STELLINK, F; BOS, AF; SCHEFFER, H; BUYS, CHCM
We report a girl with a de novo duplication of the distal part of the long arm of chromosome 3 and review the literature. Our patient had the facial characteristics and many other anomalies of the partial 3q duplication syndrome. As a hitherto undescribed symptom in partial 3q trisomy syndrome, she
The importance of education in the promotion of organ donation - doi: 10.5020/18061230.2012.p253
Taise Ribeiro Morais; Maricelma Ribeiro Morais
Transplantation and human organ donation are controversial issues that have generated much interest and discussion. The lack of clarification and the sensationalist news about organ trafficking contribute to raise questions and render the myths and prejudices permanent.The donation of organs and tissues is seen by society in general, as an act of solidarity and love from the family. However, it requires decision-making at a time of extreme pain and distress, caused by the impact of breaking ...
37 CFR 253.5 - Performance of musical compositions by public broadcasting entities licensed to colleges and...
..., Trademarks, and Copyrights COPYRIGHT OFFICE, LIBRARY OF CONGRESS COPYRIGHT ARBITRATION ROYALTY PANEL RULES... section, the rates and terms of any license agreements entered into by copyright owners and colleges... shall furnish to ASCAP, BMI and SESAC, upon request, a music-use report during one week of each...
Discovery of Isotopes of the Transuranium Elements with 93 <= Z <= 98
Fry, C
One hundred and five isotopes of the transuranium elements neptunium, plutonium, americium, curium, berkelium and californium have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.
47 CFR 25.253 - Special requirements for ancillary terrestrial components operating in the 1626.5-1660.5 MHz/1525...
... 1541.5-1547.5 MHz frequency band; (5) Exceed a total power flux density level of −56.8 dBW/m2/200 kHz... all carriers operating in the 1525-1559 MHz frequency bands. The total power flux density here is the sum of all power flux density values associated with all carriers in a sector in the 1525-1559...
A high-resolution whole genome radiation hybrid map of human chromosome 17q22-q25.3 across the genes for GH and TK
Energy Technology Data Exchange (ETDEWEB)
Foster, J.W.; Schafer, A.J.; Critcher, R. [Univ. of Cambridge (United Kingdom)] [and others
We have constructed a whole genome radiation hybrid (WG-RH) map across a region of human chromosome 17q, from growth hormone (GH) to thymidine kinase (TK). A panel of 128 WG-RH hybrid cell lines generated by X-irradiation and fusion has been tested for the retention of 39 sequence-tagged site (STS) markers by the polymerase chain reaction. This genome mapping technique has allowed the integration of existing VNTR and microsatellite markers with additional new markers and existing STS markers previously mapped to this region by other means. The WG-RH map includes eight expressed sequence tag (EST) and three anonymous markers developed for this study, together with 23 anonymous microsatellites and five existing ESTs. Analysis of these data resulted in a high-density comprehensive map across this region of the genome. A subset of these markers has been used to produce a framework map consisting of 20 loci ordered with odds greater than 1000:1. The markers are of sufficient density to build a YAC contig across this region based on marker content. We have developed sequence tags for both ends of a 2.1-Mb YAC and mapped these using the WG-RH panel, allowing a direct comparison of cRay{sub 6000} to physical distance. 31 refs., 3 figs., 2 tabs.
Directory of Open Access Journals (Sweden)
Hao Shi
Full Text Available The title compound, C17H17ClO3, has been synthesized by the reaction of p-chlorobenzaldehyde, isopropylidene malonate and 5,5-dimethylcyclohexane-1,3-dione with triethylbenzylammonium chloride in water as a green solvent. The six membered pyranone ring of the hexahydrocoumarin system has a screw-boat conformation while the dimethylcyclohexenone system has a distorted envelope conformation. The dihedral angle between the least-squares planes of the coumarin ring system and the benzene ring is 85.64 (9°.
78 FR 43888 - Compliance Policy Guide Sec. 253.100-Use of Units of Plasma and Fresh Frozen Plasma Which Have...
... published in the Federal Register on January 3, 2012 (77 FR 7), with an effective date of July 2, 2012, FDA... transfusion if stored at ] appropriate temperatures per industry standards.'' (See 77 FR 7 at 14). With this... and Fresh Frozen Plasma Which Have Been Thawed; Withdrawal of Compliance Policy Guide AGENCY: Food...
El-AbedOroub, Unprotected: Palestinians in Egypt since 1948, Washington, DC, Institute for Palestine Studies / Ottawa: International Development Research Centre, 2009, 253 p.
Directory of Open Access Journals (Sweden)
Françoise de Bel-Air
Full Text Available L'ouvrage proposé par Oroub El-Abed sur les Palestiniens d'Égypte comble un manque : cette communauté n'avait, en effet, encore jamais fait l'objet d'une étude scientifique de grande ampleur telle que celle entreprise par l'auteur sous les auspices du programme Forced Migration and Refugee Studies de l'Université américaine au Caire. L'ambition initiale de Oroub El-Abed et de son équipe était de réaliser une enquête de terrain portant sur un échantillon de 300 ménages répartis dans 15 gouvern...
SU-E-J-253: Evaluation of 4DCT Images with Correlation of RPM Signals to Tumor Motion for Respiratory-Gated Radiotherapy
International Nuclear Information System (INIS)
Purpose: The amplitudes of lung tumor target motion and RPM signals are different from each other. Also, RPM system does not have in-depth RPM signal analysis tool. We have developed an algorithm that analyzes RPM signals for its stability as well as correlativity to the tumor motion. Methods: We used a Philips Big Bore CT scanner with a Varian Real-Time Position Management™ (RPM) system attached. 4DCT images were reviewed and tumor motion amplitudes of full breathing in superior-inferior, anterior-posterior, and left-right directions were measured. RPM signals were analyzed with the algorithm developed with Matlab. Average signal period, amplitude and statistical stability of the full breathing pattern as well as the pattern around full expiration were calculated. RPM signal amplitudes were normalized to measured tumor motion amplitudes so that selected gating phases (30%–70% or 40%–60%) allow tumor motion under 5.0mm. Results: Twelve patient cases were analyzed in this study with GTV sizes ranged from 1.0cm to 3.0cm diameter. The periods and amplitudes of RPM signal ranged from 3.1seconds to 6.5seconds and from 0.2cm to 1.7cm, respectively. RPM signals were most stable at full expiration. The standard deviation of the RPM signal peaks at full expiration was <0.11cm, and that of gated amplitudes was <0.25cm. Tumor motion amplitudes were primary in superior-inferior direction and minor (<=0.2cm) in other directions on all analyzed cases, ranged from 0.2cm to 2.5cm. The amplitudes increases with the tumor located toward the diaphragm. The gated phases were selected so that the average gated tumor motion amplitude as well as that plus deviation became under 0.5cm in superior-inferior direction. Conclusion: We were able to determine the respiratory-gated phases in RPM signals employing measured tumor motion amplitudes as well as developed RPM signal analyzer through correlation process. The RPM signal amplitudes do not represent tumor motion because of its location
Neutron multiplicities for the transplutonium nuclides
International Nuclear Information System (INIS)
This paper continues, with respect to the transplutonium nuclides, earlier efforts to collate and evaluate data from the scientific literature on the prompt neutron multiplicity distribution from fission and its first moment = ΣnuPnu. The isotopes considered here for which P/sub nu/ and or data (or both) were found in the literature are of americium (Am), curium (Cm), berkelium (Bk), californium (Cf), einsteinium (Es), fermium (Fm), and nobelium (No)
"Requestioning" AIDS: An Ethical Reflection From 1993 to Today. Reflections on Claude Vandevyer's "Homosexuals and AIDS: A New Approach to the Illness" from Journal of Homosexuality 25(3).
Lau, Travis
This article serves as one of the supplementary pieces of this special issue on "Mapping Queer Bioethics," in which we take a solipsistic turn to "map" the Journal of Homosexuality itself. Here, the author examines the first feature-length article to address the relationship between HIV status and homosexuality. Lingering on both the temporal gap between the dawn of AIDS in American discourse and its inclusion in this journal, the author asks us to consider (in hindsight) such a delay bearing in mind queer theoretical projects of the present such as gay shame, stigma, and queer biopolitics.
Report on the behalf of the Parliamentary Office for the Assessment of Scientific and Technological Choices on hydrogen: a vector for energy transition? - National Assembly Nr 1672, Senate Nr 253
International Nuclear Information System (INIS)
In its first part, this report describes the role and use hydrogen may have as a possible sustainable energy vector: description of its remarkable properties, description of various production modalities and processes, issues related to storage, transport and distribution. The second part proposes an overview of applications: fuel cells, hydrogen in transports, power-to-gas, co-generation, energy autonomy, mobile devices. The third part describes and discusses the role hydrogen may have in energy transition, notably for the integration of renewable energies, and in the substitution to fossil energies. The last chapter discusses the governance for a hydrogen energy sector in France: a sector with a high potential, a needed intervention by the State, the unavoidable role of territories, the issue of regulation. A description of the situation in foreign countries is provided in appendix
"Requestioning" AIDS: An Ethical Reflection From 1993 to Today. Reflections on Claude Vandevyer's "Homosexuals and AIDS: A New Approach to the Illness" from Journal of Homosexuality 25(3).
Lau, Travis
This article serves as one of the supplementary pieces of this special issue on "Mapping Queer Bioethics," in which we take a solipsistic turn to "map" the Journal of Homosexuality itself. Here, the author examines the first feature-length article to address the relationship between HIV status and homosexuality. Lingering on both the temporal gap between the dawn of AIDS in American discourse and its inclusion in this journal, the author asks us to consider (in hindsight) such a delay bearing in mind queer theoretical projects of the present such as gay shame, stigma, and queer biopolitics. PMID:26642922
Multibeam collection for TN253: Multibeam data collected aboard Thomas G. Thompson from 2010-08-26 to 2010-09-07, departing from Astoria, OR and returning to Astoria, OR
National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...
Molecular cytogenetic analyses of HIG, a novel human cell line carrying t(1;3)(p36.3;q25.3) established from a patient with chronic myelogenous leukemia in blastic crisis.
Hosoya, Noriko; Ogawa, Seishi; Motokura, Tohru; Hangaishi, Akira; Wang, Lili; Qiao, Ying; Nannya, Yasuhito; Kogi, Mieko; Hirai, Hisamaru
Chromosomal abnormalities involving 1p36, 3q21, and/or 3q26 have been reported in a subset of myeloid neoplasms having characteristic dysmegakaryopoiesis, and the overexpression of EVI1 on 3q26 or of MEL1 on 1p36 has been implicated in their pathogenesis. We describe molecular cytogenetic analyses of a novel human cell line, HIG, established from a unique case in which a novel translocation t(1;3)(p36;q26) appeared as the sole additional chromosomal abnormality at the time of blastic transformation of chronic myelogenous leukemia. The patient displayed clinical features resembling those of the 3q21q26 syndrome. The HIG cell line retained der(1)t(1;3)(p36;q26) but lost t(9;22)(q34;q11). To identify the relevant gene that would be deregulated by this translocation, we molecularly cloned the translocation's breakpoints. They were distant from the breakpoint cluster regions of the 3q21q26 syndrome or t(1;3)(p36;q21), and neither the EVI1 nor the MEL1 transcript was detected in the HIG cell line. None of the genes located within 150 kilobase pairs of the breakpoints were aberrantly expressed, suggesting that in this case other gene(s) more distant from the breakpoints are deregulated by possible remote effects. Further analyses of the deregulated genes in the HIG cell line should provide important insight into the mechanisms involved in these types of leukemias.
Discovery of a Perseus-like cloud in the early Universe: HI-to-H2 transition, carbon monoxide and small dust grains at zabs=2.53 towards the quasar J0000+0048
Noterdaeme, P; Balashev, S; Ge, J; Gupta, N; Krühler, T; Ledoux, C; Murphy, M T; Pâris, I; Petitjean, P; Rahmani, H; Srianand, R; Ubachs, W
We present the discovery of a molecular cloud at zabs=2.5255 along the line of sight to the quasar J0000+0048. We perform a detailed analysis of the absorption lines from ionic, neutral atomic and molecular species in different excitation levels, as well as the broad-band dust extinction. We find that the absorber classifies as a Damped Lyman-alpha system (DLA) with logN(HI)(cm^-2)=20.8+/-0.1. The DLA has super-Solar metallicity with a depletion pattern typical of cold gas and an overall molecular fraction ~50%. This is the highest f-value observed to date in a high-z intervening system. Most of the molecular hydrogen arises from a clearly identified narrow (b~0.7 km/s), cold component in which CO molecules are also found, with logN(CO)~15. We study the chemical and physical conditions in the cold gas. We find that the line of sight probes the gas deep after the HI-to-H2 transition in a ~4-5 pc-size cloud with volumic density nH~80 cm^-3 and temperature of only 50 K. Our model suggests that the presence of sm...
A Response to Ages Past. Commentary on Harris, R. M., Michell, B.G. & Cooley. C. (1985) The Gender Gap in Library Education. (Journal of Education for Library and Information Science, 25(3), 167-176)
Wellstead, Peta
Much has changed in the information environment since the years of Harris' review. It is important to mention the significance of the impact of technology that has rendered the work of librarians and information workers almost unknowable to those teaching in the period 1965-1983. As a result of these reviews and technological changes, many…
Molecular cytogenetic analyses of HIG, a novel human cell line carrying t(1;3)(p36.3;q25.3) established from a patient with chronic myelogenous leukemia in blastic crisis.
Hosoya, Noriko; Ogawa, Seishi; Motokura, Tohru; Hangaishi, Akira; Wang, Lili; Qiao, Ying; Nannya, Yasuhito; Kogi, Mieko; Hirai, Hisamaru
Chromosomal abnormalities involving 1p36, 3q21, and/or 3q26 have been reported in a subset of myeloid neoplasms having characteristic dysmegakaryopoiesis, and the overexpression of EVI1 on 3q26 or of MEL1 on 1p36 has been implicated in their pathogenesis. We describe molecular cytogenetic analyses of a novel human cell line, HIG, established from a unique case in which a novel translocation t(1;3)(p36;q26) appeared as the sole additional chromosomal abnormality at the time of blastic transformation of chronic myelogenous leukemia. The patient displayed clinical features resembling those of the 3q21q26 syndrome. The HIG cell line retained der(1)t(1;3)(p36;q26) but lost t(9;22)(q34;q11). To identify the relevant gene that would be deregulated by this translocation, we molecularly cloned the translocation's breakpoints. They were distant from the breakpoint cluster regions of the 3q21q26 syndrome or t(1;3)(p36;q21), and neither the EVI1 nor the MEL1 transcript was detected in the HIG cell line. None of the genes located within 150 kilobase pairs of the breakpoints were aberrantly expressed, suggesting that in this case other gene(s) more distant from the breakpoints are deregulated by possible remote effects. Further analyses of the deregulated genes in the HIG cell line should provide important insight into the mechanisms involved in these types of leukemias. PMID:14704036
Multibeam collection for M25-3: Multibeam data collected aboard Meteor from 1993-07-04 to 1993-07-11, departing from Unknown Port and returning to Unknown Port
National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...
Composition containing transuranic elements for use in the homeopathic treatment of aids
Energy Technology Data Exchange (ETDEWEB)
Lustig, D.
A homeopathic remedy consisting of a composition containing one or more transuranic elements, particularly plutonium, for preventing and treating acquired immunodeficiency syndrome (AIDS) in humans, as well as seropositivity for human immunodeficiency virus (HIV). Said composition is characterized in that it uses any chemical or isotopic form of one or more transuranic elements (neptunium, plutonium, americium, curium, berkelium, californium or einsteinium), particularly plutonium, said form being diluted and dynamized according to conventional homeopathic methods, particularly the so-called Hahnemann and Korsakov methods, and provided preferably but not exclusively in the form of lactose and/or saccharose globules or granules impregnated with the active principle of said composition. (author).
Energy Technology Data Exchange (ETDEWEB)
Albrecht-Schmitt, Thomas
This grant supported the exploratory synthesis of new actinide materials with all of the actinides from thorium to californium with the exceptions of protactinium and berkelium. We developed detailed structure-property relationships that allowed for the identification of novel materials with selective ion-exchange, selective oxidation, and long-range magnetic ordering. We found novel bonding motifs and identified periodic trends across the actinide series. We identified structural building units that would lead to desired structural features and novel topologies. We also characterized many different spectroscopic trends across the actinide series. The grant support the preparation of approximately 1200 new compounds all of which were structurally characterized.
Detection of rare earth elements in Powder River Basin sub-bituminous coal ash using laser-induced breakdown spectroscopy (LIBS)
Energy Technology Data Exchange (ETDEWEB)
Tran, Phuoc [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State; Mcintyre, Dustin [National Energy Technology Lab. (NETL), Pittsburgh, PA, (United State
We reported our preliminary results on the use of laser-induced breakdown spectroscopy to analyze the rare earth elements contained in ash samples from Powder River Basin sub-bituminous coal (PRB-coal). We have identified many elements in the lanthanide series (cerium, europium, holmium, lanthanum, lutetium, praseodymium, promethium, samarium, terbium, ytterbium) and some elements in the actinide series (actinium, thorium, uranium, plutonium, berkelium, californium) in the ash samples. In addition, various metals were also seen to present in the ash samples
Composition containing transuranic elements for use in the homeopathic treatment of aids
International Nuclear Information System (INIS)
A homeopathic remedy consisting of a composition containing one or more transuranic elements, particularly plutonium, for preventing and treating acquired immunodeficiency syndrome (AIDS) in humans, as well as seropositivity for human immunodeficiency virus (HIV). Said composition is characterized in that it uses any chemical or isotopic form of one or more transuranic elements (neptunium, plutonium, americium, curium, berkelium, californium or einsteinium), particularly plutonium, said form being diluted and dynamized according to conventional homeopathic methods, particularly the so-called Hahnemann and Korsakov methods, and provided preferably but not exclusively in the form of lactose and/or saccharose globules or granules impregnated with the active principle of said composition. (author)
PROCEEDINGS OF THE SYMPOSIUM COMMEMORATING THE 25th ANNIVERSARY OF ELEMENTS 97 and 98 HELD ON JAN. 20, 1975
Energy Technology Data Exchange (ETDEWEB)
Seaborg, Glenn T.; Street Jr., Kenneth; Thompson, Stanley G.; Ghiorso, Albert
This volume includes the talks given on January 20, 1975, at a symposium in Berkeley on the occasion of the celebration of the 25th anniversary of the discovery of berkelium and californium. Talks were given at this symposium by the four people involved in the discovery of these elements and by a number of people who have made significant contributions in the intervening years to the investigation of their nuclear and chemical properties. The papers are being published here, without editing, in the form in which they were submitted by the authors in the months following the anniversary symposium, and they reflect rather faithfully the remarks made on that occasion.
75 FR 67771 - Notice of Determinations Regarding Eligibility To Apply for Worker Adjustment Assistance
..., Quincy, IL June 2, 2009. LLC. 74,253 International Business Phoenix, AZ June 3, 2009. Machines (IBM), Global Tech., Unix System, Support Disney, Teleworker. 74,253A International Business Costa Mesa and El...,253B International Business Atlanta, GA June 3, 2009. Machines (IBM), Global Tech., Unix...
An atomic beam source for actinide elements: concept and realization
International Nuclear Information System (INIS)
For ultratrace analysis of actinide elements and studies of their atomic properties with resonance ionization mass spectroscopy (RIMS), efficient and stable sources of actinide atomic beams are required. The thermodynamics and kinetics of the evaporation of actinide elements and oxides from a variety of metals were considered, including diffusion, desorption, and associative desorption. On this basis various sandwich-type filaments were studied. The most promising system was found to consist of tantalum as the backing material, an electrolytically deposited actinide hydroxide as the source of the element, and a titanium covering layer for its reduction to the metal. Such sandwich sources were experimentally proven to be well suited for the production of atomic beams of plutonium, curium, berkelium and californium at relatively low operating temperatures and with high and reproducible yields. (orig.)
Nuclear fission and the transuranium elements
Energy Technology Data Exchange (ETDEWEB)
Seaborg, G.T.
Many of the transuranium elements are produced and isolated in large quantities through the use of neutrons furnished by nuclear fission reactions: plutonium (atomic number 94) in ton quantities; neptunium (93), americium (95), and curium (96) in kilogram quantities; berkelium (97) in 100 milligram quantities; californium (98) in gram quantities; and einsteinium (99) in milligram quantities. Transuranium isotopes have found many practical applications---as nuclear fuel for the large-scale generation of electricity, as compact, long-lived power sources for use in space exploration, as means for diagnosis and treatment in the medical area, and as tools in numerous industrial processes. Of particular interest is the unusual chemistry and impact of these heaviest elements on the periodic table. This account will feature these aspects. 9 refs., 5 figs.
Production of transuranium elements
International Nuclear Information System (INIS)
The Radiochemical Engineering Development Center (REDC) has the programmatic responsibility for the Department of Energy's Transuranium Element Program. Principle elements from the program are einsteinium, berkelium, and fermium. Targets containing curium oxide mixed with aluminum powder are fabricated by the REDC and irradiated in the Oak Ridge National Laboratory (ORNL) High Flux Isotope Reactor. Following an irradiation period of 6-12 months, targets are returned to the REDC for chemical processing. Processing operations consists of aluminum dejacketing in a caustic-nitrate solution, filtration, acid dissolution, solvent extraction, anion exchange, and finally a cation exchange to recover the actinides. The processing operations take place in heavily shielded hot cell facilities and all operations are carried out remotely. The chemistry for the separations has been well established over the 26-yr. operating life of the facility
Choosing the Right Book: Factors that Affect Children's Reading. A Review of: Maynard, S., Mackay, S., & Smyth, F. (2008). A survey of young people's reading in England: Borrowing and choosing books. Journal of Librarianship and Information Science, 40(4), 239-253.
Gayle Bogel
Objective – To analyze factors affecting book choice: reading recommendations, reasons for choosing series books, book reviews, and school libraries.Design – This secondary analysis of data is based on a selection of findings from a larger 2005 survey that monitored trends in youth reading habits. The large scale 2005 study was designed as a follow up to a 1996 survey. The 2005 survey used online questionnaires and formal statistical analysis to compare gender and age groups. The data on fact...
Comment on Spracklandus Hoser, 2009 (Reptilia, Serpentes, ELAPIDAE): request for confirmation of availability of the generic name and for the nomenclatural validation of the journal in which it was published (Case 3601; BZN 70:234–237; 71:30–38; 133-135,181-182 ,252-253)
Rhodin, Anders G.J.; Kaiser, Hinrich; van Dijk, Peter Paul; Wüster, Wolfgang; O'Shea, Mark; Archer, Michael; Auliya, Mark; Boitani, Luigi; Bour, Roger; Clausnitzer, Viola; Contreras-MacBeath, Topiltzin; Crother, Brian I.; Daza, Juan M.; Driscoll, Carlos A.; Flores-Villela, Oscar; Frazier, Jack; Fritz, Uwe; Gardner, Alfred L.; Gascon, Claude; Georges, Arthur; Glaw, Frank; Grazziotin, Felipe G.; Groves, Colin P.; Haszprunar, Gerhard; Havaš, Peter; Hero, Jean-Marc; Hoffmann, Michael; Hoogmoed, Marinus S.; Horne, Brian D.; Iverson, John B.; Jäch, Manfred; Jenkins, Christopher L.; Jenkins, Richard K.B.; Kiester, A. Ross; Keogh, J. Scott; Lacher, Thomas E.; Lovich, Jeffrey E.; Luiselli, Luca; Mahler, D. Luke; Mallon, David P.; Mast, Roderic; McDiarmid, Roy W.; Measey, John; Mittermeier, Russell A.; Molur, Sanjay; Mosbrugger, Volker; Murphy, Robert W.; Naish, Darren; Niekisch, Manfred; Ota, Hidetoshi; Parham, James F.; Parr, Michael J.; Pilcher, Nicolas J.; Pine, Ronald H.; Rylands, Anthony B.; Sanderson, James G.; Savage, Jay M.; Schleip, Wulf; Scrocchi, Gustavo J.; Shaffer, H. Bradley; Smith, Eric N.; Sprackland, Robert; Stuart, Simon N.; Vetter, Holger; Vitt, Laurie J.; Waller, Tomás; Webb, Grahame; Wilson, Edward O.; Zaher, Hussam; Thomson, Scott
In Case 3601 Raymond Hoser has asked the Commission to validate for the purposes of nomenclature the name Spracklandus Hoser, 2009, and 'the journal in which it was published,' issue 7 of the Australasian Journal of Herpetology (AJH). We note that the entire run of AJH has been written, edited, and published solely by Hoser. Although his requests to the Commission were presented as narrow and, in his words, 'routine matters,' we are convinced that they represent an important tipping-point with broad implications of major concern for zoological taxonomy and nomenclature as a whole and, by extension, the greater scientific community. Since Hoser's actions and works have failed to follow scientific best practices (e.g. Turtle Taxonomy Working Group, 2007, 2014; Kaiser et al., 2013; Kaiser, 2014) and both the Commission's general Recommendations and Code of Ethics in Appendix A, the global herpetological community has widely rejected his taxonomic decisions and resultant nomenclature. This has unfortunately caused a confusing dual nomenclature to develop in the herpetological community, with most boycotting or ignoring Hoser's 700+ new names coined in the AJH, while he and a few personal followers actively promote their usage. We believe that suppression of the name Spracklandus, and all issues of AJH, is the only effective way to bring this contentious and confusing issue to resolution. The plenary power available under Article 81.1 of the Code exist specifically to allow the Commission to make rulings in individual cases that disturb stability and cause confusion, whether the works are Code-compliant or not. We maintain that it is in the interest of nomenclatural stability, not only for herpetology, but for all of zoological taxonomy, that the plenary power be invoked to declare the works in AJH unavailable, regardless of any narrow interpretation of their technical Code-compliance. We present our arguments for rejection of the validity of AJH in the following commentary. In view of the wide-reaching implications of this case for all of zoology, and reflecting the deep and broad-based community concern over these issues, our contributing authors include 70 global scientific leaders and accomplished amateurs from a wide variety of zoological disciplines.
Choosing the Right Book: Factors that Affect Children's Reading. A Review of: Maynard, S., Mackay, S., & Smyth, F. (2008. A survey of young people's reading in England: Borrowing and choosing books. Journal of Librarianship and Information Science, 40(4, 239-253.
Directory of Open Access Journals (Sweden)
Gayle Bogel
Full Text Available Objective – To analyze factors affecting book choice: reading recommendations, reasons for choosing series books, book reviews, and school libraries.Design – This secondary analysis of data is based on a selection of findings from a larger 2005 survey that monitored trends in youth reading habits. The large scale 2005 study was designed as a follow up to a 1996 survey. The 2005 survey used online questionnaires and formal statistical analysis to compare gender and age groups. The data on factors affecting book choice were derived from the original questions, responses, and analyses.Setting – Questionnaires were administered in22 primary and 24 secondary schools in the UK with access to computers and internet.Subjects – Almost 4,200 students from 4 to 16 years of age.Methods – Study authors invited approximately 150 schools to participate in the survey. Forty-six schools (31% responded. A total of 22 primary and 24 secondary schools participated in the original study between April and June 2005.This study used comparative analysis to examine factors affecting book choice between gender and age groups. Statistical significance was defined as one percent. Other demographic information was collected, such as ethnicity, language spoken at home, and religion, but was deemed insufficient for any meaningful analysis.There were 4,182 responses to the survey, separated into three age groups: ages 4 to 7 (KS1, ages 7 to 11 (KS2, and ages 11 to 16 (KS3&4.Students were asked to describe themselves as readers by responding to multiple choice questions, and then to provide specific information on the places or people most frequently used as book borrowing sources. Participants were considered "enthusiastic" readers if they "read a lot with pleasure" and "average" readers if they "read an ordinary amount". Participants responded to additional multiple choice questions on specific factors related to borrowing books and book choices, the process of choosing series, fiction, and nonfiction books.Main Results – Readers: The number of children who described themselves as "enthusiastic" readers decreased with age, and approximately half of the children between 7 and 16 years of age described themselves as "average" readers, average rating increasing slightly through this age group. Investigators found a marked difference in gender within the 4 to 7 year olds: 49.7% percent of girls in this age group considered themselves "enthusiastic," compared to 37.3% of boys. Only 18.5% of girls considered themselves "reluctant" readers, compared to 28.1% of boys.The longitudinal comparison to the earlier 1996 study found that although the percentage of boys from ages 7 to 16 who described themselves as reluctant readers stayed about the same, the percentage of girls who described themselves as reluctant increased. There was also a dramatic drop in the number of girls who described themselves as enthusiastic; from 51% in 1996 to 17% in 2005.Borrowing Books: Libraries of all types (school, classroom and public were the prime sources for borrowing books. Girls borrowed more books from schools than boys, and girls also borrowed more books from non-library sources (family members and friends than boys. Both boys and girls increasingly reported borrowing more books from friends than from libraries as they grew older.Over half of each age group rated the school library or classroom book corner as having "enough" books. The perception of "too many books" decreased with age. The perception of quality of the classroom or school library also decreased with age. The number of students in the younger age groups who rated the quality of books in the classroom or school library as "very good" was significantly higher than students in the older age groups. The number of student who rated the quality as "okay" doubled from the lower to the higher age group.Choosing Books: Children were asked six questions related to whether the physical book itself provided motivation to read, and six questions related to other factors for book recommendation. Younger readers were more likely to choose a book for its visual appeal, although this factor (interesting cover or illustrations inside was more consistent for boys of all age groups than girls. The author's name and book blurb were stronger factors for girls in the 7 to 16 age group than for boys.The study authors sought to explore the idea of "shared reading" and asked children in the 7 to 11 and 11 to 16 age groups how often they chose a book based on a recommendation from a friend or family member, a public or school librarian, or other adults. Friends were the strongest recommendation source (43.2% for 7 to 11 year olds and 38.4% for 11to 16 year olds. Recommendations from school or public librarians rated only three to six percent for both age groups.All age groups were asked about choosing series books, and the questions were simplified for the younger age group. All students reported that appealing factors were the consistency of characters, familiar storylines, and familiar writing styles. Some students also noted that the availability of series books positively affected their choices.Print or online book reviews were used "hardly ever or never" by over 40% of the 7 to16 year old age groups, while television or magazine reviews or recommendations were highly rated by over 50% of respondents in the same age groups. Participants chose informational or non-fiction books because of personal interests, hobbies, or recommendations from friends, while they selected fiction or poetry for the blurb, title, or appearance and design of the cover. Celebrity recommendations and books about celebrities were popular reasons for choosing books.When asked who helped them choose books, 53.2% in the 7 to11 age group and 66.1% in the 11to 16 age group stated that no one ever helps them. Of the students who had help choosing books, "family members" was the most common response. Local librarians were not used as a source for recommendations.
Questions Remain about Whether EBM Competencies Learned in Medical School are Retained in Residency. A review of: Dorsch, Josephine L., Meenakshy K. Aiyer, Krishna Gumidyala and Lynne E. Myer. "Retention of EBM Competencies." Medical Reference Services Quarterly 25.3 (Fall 2006: 45‐57.
Directory of Open Access Journals (Sweden)
Suzanne Lewis
Full Text Available Objective – To assess medical graduates' use of evidence based medicine (EBM in residency, self‐perception of EBM skills, attitudes toward EBM, and the impact of a formal EBM curriculum in their third undergraduate year.Design – A longitudinal follow‐up study by self‐administered questionnaire.Setting – Internal medicine residency programs in US hospitals.Subjects – A convenience sample of 2001 and 2002 graduates of the University of Illinois College of Medicine at Peoria (UICOM‐P (n=78, and their respective residency program directors (n=72.Methods – A student graduate questionnaire (SGQ was sent to all members of UICOM‐P's 2001 and 2002 graduating classes who had completed the EBM course during their M‐3 Internal Medicine clerkship. A program director questionnaire (PDQ, similar to the SGQ, was sent to the graduates' residency program directors. The research instrument was tested with a pilot group prior to use, but not validated. The questionnaires consisted of 4 main sections. The first section examined formal and informal EBM programs in the graduates' residency curriculum. The second section consisted of a self‐assessment of EBM skills by the residents and an assessment of those skills by their program directors. The third section asked graduates to compare their EBM skills to those of their fellow residents who had not been students at UICOM‐P. Similarly, in the third section of the PDQ, program directors were asked to compare the EBM skills of UICOM‐P graduates and non‐UICOM‐P graduates participating in the residency program. The last section concerned professional and demographic characteristics. Copies of the surveys were mailed out to non‐responders after 6 weeks. Results were collated but statistical analysis was not applied.Main results – The response rate was 32% for residents and 35% for program directors. The number of incomplete surveys was not reported. Forty‐four percent of all respondents reported having a formal EBM curriculum for residents, and 76% reported an informal curriculum. For both formal and informal programs, the most commonteaching formats were journal clubs, followed by lectures, teaching rounds, morning reports, bedside consultations, ambulatory clinics and seminars. In section two of the questionnaires, both residentsand program directors rated the residents' EBM skills similarly. However, the residents rated their skills in searching the literatureand application of findings to clinical practice higher than the program directors. Program directors also rated the residents' skills in understanding statistics and tests higher than the residents themselves. Twenty‐four percent of both residents and program directors rated the UICOM‐P graduates as "very competent" or"extremely competent" in EBM skills (50. Only 35% of program directors and 27% of residents rated the UICOM‐P graduates' EBM skills as "usually better" or "always better" than their peers who were not UICOM‐P graduates (50.Conclusion ‐ The authors of this study conclude that, for UICOM‐P graduates, "it might be implied from these results that the EBM skills gained during medical school were retained through their medical school graduation and into their residency training" (51. However, this study has methodological weaknesses which make itdifficult to draw any definite conclusions from the results.
Questions Remain about Whether EBM Competencies Learned in Medical School are Retained in Residency. A review of: Dorsch, Josephine L., Meenakshy K. Aiyer, Krishna Gumidyala and Lynne E. Myer. "Retention of EBM Competencies." Medical Reference Services Quarterly 25.3 (Fall 2006): 45‐57.
Suzanne Lewis
Objective – To assess medical graduates' use of evidence based medicine (EBM) in residency, self‐perception of EBM skills, attitudes toward EBM, and the impact of a formal EBM curriculum in their third undergraduate year.Design – A longitudinal follow‐up study by self‐administered questionnaire.Setting – Internal medicine residency programs in US hospitals.Subjects – A convenience sample of 2001 and 2002 graduates of the University of Illinois College of Medicine at Peoria (UICOM‐P) (n=78), a...
Decision of the Constitutional Review Division of the National Court of The Republic of Estonia : 30 September 1994 : review of the constitutionality of § 25(3) of the Property Law Enforcement Act to the extent that it sought to repeal § 30(2) of t
Riigikohtu lahendi III-4/A-5/94 (Asjaõigusseaduse rakendamise seaduse § 25 lg. 3 Põhiseadusele vastavuse läbivaatamine Eesti NSV taluseaduse § 30 lg. 2 kehtetuks tunnistamise osas) tekst inglise keeles
Deme accounts and the meaning of hosios money in fifth-century Athens
Blok, J.H.
Comparing the accounts of the deme Ikarion (IG I3 253) with those of Rhamnous (IG I3 247 bis and 253; IRhamnous 181 and 182) and Plotheia (IG I3 258), this article argues that the adjective hosios applied to a fund in Ikarion indicates that this money was dêmosios and to be used in a way pleasing to
Institute of Scientific and Technical Information of China (English)
25.3 % China's industrial enterprises with annual sales revenue of more than 20 million yuan ($3.2 million) saw their profits increase 25.3 percent year on year in the first 10 months of 2011, said the National Bureau of Statistics.
Dicty_cDB: Contig-U09091-1 [Dicty_cDB
Lifescience Database Archive (English)
Full Text Available 53 Score = 180 bits (91), Expect = 1e-45 Identities = 253/253 (100%) Strand = Plus / Plus Query: 234 tcccnat...ntanactaccnctggncaaantaaaactggtttngcnccnantgcaancggnt 293 |||||||||||||||||||||||...||||||||||||||||||||||||||||||||||||| Sbjct: 234 tcccnatntanactaccnctggncaaantaaaactggtttngcnccnantgcaancggn...acncgncnttggangnattgga 413 Query: 414 aancngnccttttaggggcnggnttancnggntttgcccnaaa...nttanttggnaannattggacncgncnttgg 152 Query: 404 angnattggaaancngnccttttaggggcnggnttancnggntttgcccna
Thin-sheet flow between coalescing bubbles
Munro, James?P.; Anthony, Christopher?R.; Basaran, Osman A.; Lister, John R.
This is the accepted manuscript of a paper published in the Journal of Fluid Mechanics (Munro JP, Anthony CR, Basaran OA, Lister JR, Journal of Fluid Mechanics, 2015, 773, doi:10.1017/jfm.2015.253). The final version is available at http://dx.doi.org/10.1017/jfm.2015.253
QTL Information Table: 659 [Q-TARO
Lifescience Database Archive (English)
Full Text Available age Mixture C)Interval F2 Kunmingxiaobaigu Towada R1954 RM253 jsa Dai, L., Lin, X., Ye, C., Ise, K., Saito, ...ld Tolerance at the Reproductive Stage in Yunnan Landrace of Rice, Kunmingxiaobaigu. Breeding Science 54, 253-258. ...
Lifescience Database Archive (English)
Full Text Available FP uniform epi Larval X-gal uni epi, Adult GFP leg joints. wing hinge. Lethality ...niform epi uni epi, leg joints. wing hinge. - - - - - - - Show 113400 DGRC Number...etics. FM7c Link to clone table - 1 253 Link to cluster table 253 1 Request - epi (SG), a small # of cells u
75 FR 43115 - National Oil and Hazardous Substances Pollution Contingency Plan; National Priorities List...
... AGENCY 40 CFR Part 300 National Oil and Hazardous Substances Pollution Contingency Plan; National..., and Liability Act (CERCLA) of 1980, as amended, is an appendix of the National Oil and Hazardous... partial deletion pertains to the soil and groundwater of parcels 24, 27, 28, 2-53, 2-53L, 2-54, 2-54L,...
Nuclear Chemistry Institute, Mainz University. Annual Report 1995
International Nuclear Information System (INIS)
The annual report of the Institut fuer Kernchemie addresses inter alia three main research activities. The first belongs to the area of basic research, covering studies in the fields of nuclear fission, chemistry of the super-heavy elements and of heavy-ion reactions extending from the Coulomb barrier to relativistic energies, and nuclear astrophysics in connection with the ''r process''. By means of laser technology, high-precision data could be measured of the ionization energies of berkelium and californium. Studies of atomic clusters in the vacuum of an ionization trap revealed interesting aspects. The second major activity was devoted to the analysis of environmental media, applying inter alia neutron activation analysis and resonance ionization mass spectroscopy (RIMS). The third activity resulted in the development of novel processes, or the enhancement of existing processes or methods, for applications in basic research work and in environmental analytics. Another item of interest is the summarizing report on the operation of the TRIGA research reactor. (orig./SR)
Characterization of a Viking Blade Fabricated by Traditional Forging Techniques
Vo, H.; Frazer, D.; Bailey, N.; Traylor, R.; Austin, J.; Pringle, J.; Bickel, J.; Connick, R.; Connick, W.; Hosemann, P.
A team of students from the University of California, Berkeley, participated in a blade-smithing competition hosted by the Minerals, Metals, and Materials Society at the TMS 2015 144th annual meeting and exhibition. Motivated by ancient forging methods, the UC Berkeley team chose to fabricate our blade from historical smithing techniques utilizing naturally-occurring deposits of iron ore. This approach resulted in receiving the "Best Example of a Traditional Blade Process/Ore Smelting Technique" award for our blade named "Berkelium." First, iron-enriched sand was collected from local beaches. Magnetite (Fe3O4) was then extracted from the sand and smelted into individual high- and low-carbon steel ingots. Layers of high- and low-carbon steels were forge-welded together, predominantly by hand, to form a composite material. Optical microscopy, energy dispersive spectroscopy, and Vickers hardness mechanical testing were conducted at different stages throughout the blade-making process to evaluate the microstructure and hardness evolution during formation. It was found that the pre-heat-treated blade microstructure was composed of ferrite and pearlite, and contained many nonmetallic inclusions. A final heat treatment was performed, which caused the average hardness of the blade edge to increase by more than a factor of two, indicating a martensitic transformation.
Paul Scherrer Institute Scientific Report 1999. Volume I: Particles and Matter
International Nuclear Information System (INIS)
Although originally planned for fundamental research in nuclear physics, the particle beams of pions, muons, protons and neutrons are now used in a large variety of disciplines in both natural science and medicine. The beams at PSI have the world's highest intensities and therefore allow certain experiments to be performed, which would not be possible elsewhere. The highlight of research this year was the first-ever determination of the chemical properties of the superheavy element 107 Bohrium. This was undertaken, by an international team led by H. Gaeggeler of PSI's Laboratory for Radiochemistry. Bohrium was produced by bombarding a Berkelium target with Neon ions from the Injector I cyclotron and six atoms were detected after having passed through an online gas chromatography device. At the Laboratory for Particle Physics the focus has shifted from nuclear physics to elementary particle physics with about a fifty-fifty split between investigations of rare processes or particle decays using the high intensity muon, pion and recently also polarized neutron beams of PSI, and research at the highest energy frontier at CERN (Geneva) and DESY (Hamburg). Important space instrumentation has been contributed by the Laboratory for Astrophysics to the European Space Agency and NASA satellite programmes. The Laboratory for Micro and Nanotechnology continued to focus on research into molecular nanotechnology and SiGeC nanostructures, the latter with the aim of producing silicon based optoelectronics. Progress in 1999 in these topical areas is described in this report. A list of scientific publications in 1999 is also provided
Structures of BmrR-Drug Complexes Reveal a Rigid Multidrug Binding Pocket And Transcription Activation Through Tyrosine Expulsion
Energy Technology Data Exchange (ETDEWEB)
Newberry, K.J.; Huffman, J.L.; Miller, M.C.; Vazquez-Laslop, N.; Neyfakh, A.A.; Brennan, R.G.
BmrR is a member of the MerR family and a multidrug binding transcription factor that up-regulates the expression of the bmr multidrug efflux transporter gene in response to myriad lipophilic cationic compounds. The structural mechanism by which BmrR binds these chemically and structurally different drugs and subsequently activates transcription is poorly understood. Here, we describe the crystal structures of BmrR bound to rhodamine 6G (R6G) or berberine (Ber) and cognate DNA. These structures reveal each drug stacks against multiple aromatic residues with their positive charges most proximal to the carboxylate group of Glu-253 and that, unlike other multidrug binding pockets, that of BmrR is rigid. Substitution of Glu-253 with either alanine (E253A) or glutamine (E253Q) results in unpredictable binding affinities for R6G, Ber, and tetraphenylphosphonium. Moreover, these drug binding studies reveal that the negative charge of Glu-253 is not important for high affinity binding to Ber and tetraphenylphosphonium but plays a more significant, but unpredictable, role in R6G binding. In vitro transcription data show that E253A and E253Q are constitutively active, and structures of the drug-free E253A-DNA and E253Q-DNA complexes support a transcription activation mechanism requiring the expulsion of Tyr-152 from the multidrug binding pocket. In sum, these data delineate the mechanism by which BmrR binds lipophilic, monovalent cationic compounds and suggest the importance of the redundant negative electrostatic nature of this rigid drug binding pocket that can be used to discriminate against molecules that are not substrates of the Bmr multidrug efflux pump.
... Disorders of vitamin D metabolism Kidney failure and acidosis Lack of enough phosphates in the diet Liver ... PA: Saunders Elsevier; 2011:chap 253. Read More Acidosis Acute kidney failure Lactose intolerance Malabsorption Rickets Seizures ...
75 FR 12761 - Government-Owned Inventions; Availability for Licensing
... Huntington's, amyotrophic lateral sclerosis, ischemia, rheumatoid arthritis, osteoarthritis, inflammatory... instance, rheumatoid arthritis alone affects 1% of the population, or about 2.5-3 million Americans... the Treatment of Pulmonary Disease Description of Invention: Investigators at the National Heart,...
Experiment list: SRX337965 [Chip-atlas[Archive
Lifescience Database Archive (English)
Full Text Available ODENDROCYTES in the CENTRAL NERVOUS SYSTEM. Malignant peripheral nerve sheath tumors, NEUROFIBROMA, and NEUR...ILEMMOMA are relatively common tumors in this category. 9918784,96.3,19.7,253 GSM
76 FR 32986 - National Capital Memorial Advisory Commission Meeting
.... (b) S. 253 and H.R. 938, bills to establish a World War I National Memorial Commission and reestablish the District of Columbia World War Memorial as the National World War I Memorial. (c) S. 883,...
Institute of Scientific and Technical Information of China (English)
@@ The foiled bid to blow Northwest Airlines Flight 253 from the skies above Detroit on December 25, 2009, was very nearly the second most serious incident in the United States associated with AI Qaeda since 9/11.
Institute of Scientific and Technical Information of China (English)
HUANGMing-Kong; MATian-Gen
253 cases without any complcation and 20 cases with sore vasitis node and epididymal stasis were selected at random among those who had reccived vasectomy in an epidcmiological study on the safety of vasectomy. 319 married men having offsprings
Institute of Scientific and Technical Information of China (English)
253 Million Internet Users vs 46.4 Percent of Women Netizens China Internet Network Information Center(CNNIC) recently issued its 22nd Statistical Survey Report on Internet Development in China. The report indicated China had 253 million Internet users by the end of June 2008, up 56.2 percent over the previous year.For the first time in China's history,the Internet
Gclust Server: 98465 [Gclust Server
Lifescience Database Archive (English)
Full Text Available uence length 253 Representative annotation dehydrogenase with different specificities...98465 Pm4_PMT9312_1351 Cluster Sequences Related Sequences(192) 253 dehydrogenase with different specificiti...es 1 1.00e-99 0.0 0.0 4.0 0.0 0.0 0.0 Show 98465 Cluster ID 98465 Sequence ID Pm4_P
Lifescience Database Archive (English)
Full Text Available D00447 Drug Sulfamethoxazole (JP16/USP/INN); Gantanol (TN) C10H11N3O3S 253.0521 253... Intermediate-acting sulfonamides J01EC01 Sulfamethoxazole D00447 Sulfamethoxazole (JP16/USP/INN) Antiinfect...e synthase inhibitor [KO:K00796] Sulfonamides Sulfamethoxazole [ATC:J01EC01] D00447 Sulfamethoxazole (JP16/U
1α,25(OH)2D3 differentially regulates miRNA expression in human bladder cancer cells.
Ma, Yingyu; Hu, Qiang; Luo, Wei; Pratt, Rachel N; Glenn, Sean T; Liu, Song; Trump, Donald L; Johnson, Candace S
Bladder cancer is the fourth most commonly diagnosed cancer in men and eighth leading cause of cancer-related death in the US. Epidemiological and experimental studies strongly suggest a role for 1α,25(OH)2D3 in cancer prevention and treatment. The antitumor activities of 1α,25(OH)2D3 are mediated by the induction of cell cycle arrest, apoptosis, differentiation and the inhibition of angiogenesis and metastasis. miRNAs play important regulatory roles in cancer development and progression. However, the role of 1α,25(OH)2D3 in the regulation of miRNA expression and the potential impact in bladder cancer has not been investigated. Therefore, we studied 1α,25(OH)2D3-regulated miRNA expression profiles in human bladder cancer cell line 253J and the highly tumorigenic and metastatic derivative line 253J-BV by miRNA qPCR panels. 253J and 253J-BV cells express endogenous vitamin D receptor (VDR), which can be further induced by 1α,25(OH)2D3. VDR target gene 24-hydroxylase was induced by 1α,25(OH)2D3 in both cell lines, indicating functional 1α,25(OH)2D3 signaling. The miRNA qPCR panel assay results showed that 253J and 253J-BV cells have distinct miRNA expression profiles. Further, 1α,25(OH)2D3 differentially regulated miRNA expression profiles in 253J and 253J-BV cells in a dynamic manner. Pathway analysis of the miRNA target genes revealed distinct patterns of contribution to the molecular functions and biological processes in the two cell lines. In conclusion, 1α,25(OH)2D3 differentially regulates the expression of miRNAs, which may contribute to distinct biological functions, in human bladder 253J and 253J-BV cells. This article is part of a Special Issue entitled '17th Vitamin D Workshop'. PMID:25263658
1α,25(OH)2D3 differentially regulates miRNA expression in human bladder cancer cells.
Ma, Yingyu; Hu, Qiang; Luo, Wei; Pratt, Rachel N; Glenn, Sean T; Liu, Song; Trump, Donald L; Johnson, Candace S
Bladder cancer is the fourth most commonly diagnosed cancer in men and eighth leading cause of cancer-related death in the US. Epidemiological and experimental studies strongly suggest a role for 1α,25(OH)2D3 in cancer prevention and treatment. The antitumor activities of 1α,25(OH)2D3 are mediated by the induction of cell cycle arrest, apoptosis, differentiation and the inhibition of angiogenesis and metastasis. miRNAs play important regulatory roles in cancer development and progression. However, the role of 1α,25(OH)2D3 in the regulation of miRNA expression and the potential impact in bladder cancer has not been investigated. Therefore, we studied 1α,25(OH)2D3-regulated miRNA expression profiles in human bladder cancer cell line 253J and the highly tumorigenic and metastatic derivative line 253J-BV by miRNA qPCR panels. 253J and 253J-BV cells express endogenous vitamin D receptor (VDR), which can be further induced by 1α,25(OH)2D3. VDR target gene 24-hydroxylase was induced by 1α,25(OH)2D3 in both cell lines, indicating functional 1α,25(OH)2D3 signaling. The miRNA qPCR panel assay results showed that 253J and 253J-BV cells have distinct miRNA expression profiles. Further, 1α,25(OH)2D3 differentially regulated miRNA expression profiles in 253J and 253J-BV cells in a dynamic manner. Pathway analysis of the miRNA target genes revealed distinct patterns of contribution to the molecular functions and biological processes in the two cell lines. In conclusion, 1α,25(OH)2D3 differentially regulates the expression of miRNAs, which may contribute to distinct biological functions, in human bladder 253J and 253J-BV cells. This article is part of a Special Issue entitled '17th Vitamin D Workshop'.
Minor Actinide Burning in Thermal Reactors. A Report by the Working Party on Scientific Issues of Reactor Systems
International Nuclear Information System (INIS)
The actinides (or actinoids) are those elements in the periodic table from actinium upwards. Uranium (U) and plutonium (Pu) are two of the principal elements in nuclear fuel that could be classed as major actinides. The minor actinides are normally taken to be the triad of neptunium (Np), americium (Am) and curium (Cm). The combined masses of the remaining actinides (i.e. actinium, thorium, protactinium, berkelium, californium, einsteinium and fermium) are small enough to be regarded as very minor trace contaminants in nuclear fuel. Those elements above uranium in the periodic table are known collectively as the transuranics (TRUs). The operation of a nuclear reactor produces large quantities of irradiated fuel (sometimes referred to as spent fuel), which is either stored prior to eventual deep geological disposal or reprocessed to enable actinide recycling. A modern light water reactor (LWR) of 1 GWe capacity will typically discharge about 20-25 tonnes of irradiated fuel per year of operation. About 93-94% of the mass of uranium oxide irradiated fuel is comprised of uranium (mostly 238U), with about 4-5% fission products and ∼1% plutonium. About 0.1-0.2% of the mass is comprised of neptunium, americium and curium. These latter elements accumulate in nuclear fuel because of neutron captures, and they contribute significantly to decay heat loading and neutron output, as well as to the overall radio-toxic hazard of spent fuel. Although the total minor actinide mass is relatively small - approximately 20-25 kg per year from a 1 GWe LWR - it has a disproportionate impact on spent fuel disposal, and thus the longstanding interest in transmuting these actinides either by fission (to fission products) or neutron capture in order to reduce their impact on the back end of the fuel cycle. The combined masses of the trace actinides actinium, thorium, protactinium, berkelium and californium in irradiated LWR fuel are only about 2 parts per billion, which is far too low for
Actinide production in the reaction of heavy ions with curium-248
International Nuclear Information System (INIS)
Chemical experiments were performed to examine the usefulness of heavy ion transfer reactions in producing new, neutron-rich actinide nuclides. A general quasi-elastic to deep-inelastic mechanism is proposed, and the utility of this method as opposed to other methods (e.g. complete fusion) is discussed. The relative merits of various techniques of actinide target synthesis are discussed. A description is given of a target system designed to remove the large amounts of heat generated by the passage of a heavy ion beam through matter, thereby maximizing the beam intensity which can be safely used in an experiment. Also described is a general separation scheme for the actinide elements from protactinium (Z=91) to mendelevium (Z=101), and fast specific procedures for plutonium, americium and berkelium. The cross sections for the production of several nuclides from the bombardment of 248Cm with 18O, 86Kr and 136Xe projectiles at several energies near and below the Coulomb barrier were determined. The results are compared with yields from 48Ca and 238U bombardments of 248Cm. Simple extrapolation of the product yields into unknown regions of charge and mass indicates that the use of heavy ion transfer reactions to produce new, neutron-rich above-target species is limited. The substantial production of neutron-rich below-target species, however, indicates that with very heavy ions like 136Xe and 238U the new species 248Am, 249Am and 247Pu should be produced with large cross sections from a 248Cm target. A preliminary, unsuccessful attempt to isolate 247Pu is outlined. The failure is probably due to the half life of the decay, which is calculated to be less than 3 minutes. The absolute gamma ray intensities from 251Bk decay, necessary for calculating the 251Bk cross section, are also determined
Paul Scherrer Institute Scientific Report 1999. Volume I: Particles and Matter
Energy Technology Data Exchange (ETDEWEB)
Gobrecht, J.; Gaeggeler, H.; Herlach, D.; Junker, K.; Kettle, P.-R.; Kubik, P.; Zehnder, A. [eds.
lthough originally planned for fundamental research in nuclear physics, the particle beams of pions, muons, protons and neutrons are now used in a large variety of disciplines in both natural science and medicine. The beams at PSI have the world's highest intensities and therefore allow certain experiments to be performed, which would not be possible elsewhere. The highlight of research this year was the first-ever determination of the chemical properties of the superheavy element {sup 107} Bohrium. This was undertaken, by an international team led by H. Gaeggeler of PSI's Laboratory for Radiochemistry. Bohrium was produced by bombarding a Berkelium target with Neon ions from the Injector I cyclotron and six atoms were detected after having passed through an online gas chromatography device. At the Laboratory for Particle Physics the focus has shifted from nuclear physics to elementary particle physics with about a fifty-fifty split between investigations of rare processes or particle decays using the high intensity muon, pion and recently also polarized neutron beams of PSI, and research at the highest energy frontier at CERN (Geneva) and DESY (Hamburg). Important space instrumentation has been contributed by the Laboratory for Astrophysics to the European Space Agency and NASA satellite programmes. The Laboratory for Micro and Nanotechnology continued to focus on research into molecular nanotechnology and SiGeC nanostructures, the latter with the aim of producing silicon based optoelectronics. Progress in 1999 in these topical areas is described in this report. A list of scientific publications in 1999 is also provided.
Transuranium Processing Plant semiannual report of production, status, and plans for period ending December 31, 1975
Energy Technology Data Exchange (ETDEWEB)
King, L.J.; Bigelow, J.E.; Collins, E.D.
Between July 1, 1975, and December 31, 1975, maintenance was conducted at TRU for a period of three months, 295 g of curium oxide (enough for approximately 26 HFIR targets) were prepared, 100 mg of high-purity /sup 248/Cm, were separated from /sup 252/Cf that had been purified during earlier periods, 11 HFIR targets were fabricated, and 28 product shipments were made. No changes were made in the chemical processing flowsheets normally used at TRU during this report period. However, three equipment racks were replaced (with two new racks) during this time. In Cubicle 6, the equipment replaced was that used to decontaminate the transplutonium elements from rare earth fission products and to separate curium from the heavier elements by means of the LiCl-based anion-exchange process. In Cubicle 5, the equipment used to separate the transcurium elements by high-pressure ion exchange and to purify berkelium by batch solvent extraction was replaced. Two neutron sources were fabricated, bringing the total fabricated to 79. One source that had been used in a completed project was returned to the TRU inventory and is available for reissue. Three sources, for which no further use was foreseen, were processed to isolate and recover the ingrown /sup 248/Cm and the residual /sup 252/Cf. Eight pellets, each containing 100 ..mu..g of high-purity /sup 248/Cm were prepared for irradiation in HFIR to study the production of /sup 250/Cm. The values currently being used for transuranium element decay data and for cross-section data in planning irradiation-processing cycles, calculating production forecasts, and assaying products are tabulated.
模糊数学法在苹果醋市场调查中的应用%AppI ication of Fuzzy Mathematics in Market Research on AppIe Vinegar
Institute of Scientific and Technical Information of China (English)
常陆林; 魏永义; 尹军杰; 王富刚
采用模糊数学法对编号625,560,329,208,253的5种苹果醋进行了市场调查分析,结果表明:5个样品综合评定结果全部为二级,5种苹果醋市场调查的结果从高到低依次为329>253>625>560>208。%Fuzzy mathematics is applied to evaluate the market research on five kinds of apple vinegar. The results show that the rank of comprehensive evaluation of five kinds of apple vinegar is all level II.The analysis of market research on five kinds of apple vinegar is ranked as follows:329>253>625>560>208.
An Exponential Stability Result of a Timoshenko System with Thermoelasticity with Second Sound and in the Presence of Delay
International Nuclear Information System (INIS)
In this paper, we consider a one-dimensional linear thermoelastic system of Timoshenko type with a delay, where the heat flux is given by Cattaneo's law. We prove an exponential decay result under a smallness condition on the delay and a stability number introduced first in Santos et al. (J Diff Eqs 253:2715–2733, 2012), using a method different from that of Santos et al. (J Diff Eqs 253:2715–2733, 2012). We also reproduce the polynomial decay of Santos et al. (J Diff Eqs 253:2715–2733, 2012) using the multiplier method in the case of absence of delay. The polynomial decay issue in the presence of a small delay is an open question
Formation of the XeI excimer sustained by dielectric barrier discharge in Xe/I2 at low pressure
Institute of Scientific and Technical Information of China (English)
张连水; 赵晓辉; 韩理
Dielectric barrier discharge is used to study the mechanism of XeI excimer formation in the mixture of Xe and I2 at low pressures (<1330 Pa). Fluorescence emission in the spectral region of 200-260nm is examined. We report on the characteristics of the 253 nm emission intensity which varied with different total pressure. The results indicate that under the present experimental conditions, electron impact is the major reaction producing the excimer XeI(B), interpreted as Xe++I2- →XeI(B)+ I*, then radiating 253 nm fluorescence from transition B→X. The 253 nm emission increases with the total gas pressure up to a maximum value at a pressure of about 540 Pa, then decreases as the gas pressure is further increased. The 206 nm emission is determined by I* from ionic recombination between Xe+ and I2-. This result differs from previous works under other experimental conditions.
[Microbiological study of male genital ulcers. Apropos of 75 cases].
Casin, I; Bianchi, A; Ramel, F; Lajoie, C; Chastang, C; Scieux, C; Ferchal, F; Janier, M; Morel, P; Perol, Y
Between November 1986 and June 1987, the microbial aetiology of genital ulcers was assessed in 75 male patients attending the Sexually Transmitted Disease (STD) clinic in Hôpital Saint-Louis, Paris. Evidence of Haemophilus ducreyi was found in 18 patients (24%), Herpes simplex virus in 19 (25.3%). Syphilis was diagnosed on the basis of dark field microscopy and/or positive serology test in 19 patients (25.3%). Lymphogranuloma venereum was not diagnosed in any patient. Primary pathogens were not identified from the remaining 19 (25.3%) men. Neisseria gonorrhoea was isolated in five patients, from the ulcer in three cases, from the urethra in two. Asymptomatic urethral carriage of Chlamydia trachomatis was culture proven in seven cases. The presence of IgM antibodies to C. trachomatis at a titre greater than 40 found in 17 patients was a indication of a current chlamydial infection. Three patients (4%) were discovered to be HIV-1 positive.
A human β-III-spectrin spinocerebellar ataxia type 5 mutation causes high-affinity F-actin binding.
Avery, Adam W; Crain, Jonathan; Thomas, David D; Hays, Thomas S
Spinocerebellar ataxia type 5 (SCA5) is a human neurodegenerative disease that stems from mutations in the SPTBN2 gene encoding the protein β-III-spectrin. Here we investigated the molecular consequence of a SCA5 missense mutation that results in a L253P substitution in the actin-binding domain (ABD) of β-III-spectrin. We report that the L253P substitution in the isolated β-III-spectrin ABD causes strikingly high F-actin binding affinity (Kd = 75.5 nM) compared to the weak F-actin binding affinity of the wild-type ABD (Kd = 75.8 μM). The mutation also causes decreased thermal stability (Tm = 44.6 °C vs 59.5 °C). Structural analyses indicate that leucine 253 is in a loop at the interface of the tandem calponin homology (CH) domains comprising the ABD. Leucine 253 is predicted to form hydrophobic contacts that bridge the CH domains. The decreased stability of the mutant indicates that these bridging interactions are probably disrupted, suggesting that the high F-actin binding affinity of the mutant is due to opening of the CH domain interface. These results support a fundamental role for leucine 253 in regulating opening of the CH domain interface and binding of the ABD to F-actin. This study indicates that high-affinity actin binding of L253P β-III-spectrin is a likely driver of neurodegeneration. PMID:26883385
Development and application of heat resistance stainless steel micro alloying with rare earth elements%稀土元素微合金化耐热不锈钢的开发与应用
Institute of Scientific and Technical Information of China (English)
Austenitic heat resisting stainless steels were alloyed by optimizing chemical composition and adding small amount of rare earths,N and Si.The effect of these elements on the typical grade Therma 253MA was studied by means of high temperature tensile and oxidation tests.The results show that the strength at ambient temperature and the creep strength are increased largely and oxidation resistance in dry air is improved.These properties of Therma 253MA are superior to those of commonly used austenitic heat resisting stainless steels 310S and 309S.In many cases,Therma 253MA steel can replace 310S and 309S,providing prolonged life time of equipment and reducing amount of material used with a obvious benefit for the future.%对奥氏体耐热不锈钢进行合理合金化,在化学成分方面进行了优化,加入了微量的稀土元素,适量的氮和硅元素.以典型钢种Therma 253MA为例,通过高温力学性能和氧化试验,对这些元素的作用进行了研究.结果表明,合金化后Therma 253MA的室温强度和高温蠕变强度都有较大的提高,干燥空气中的抗氧化性能也大大改善,性能均优越于目前常用奥氏体耐热不锈钢309S和310S等钢种.在许多情况下,Therma 253MA 可以完全取代310S和309S,延长设备的使用寿命、减少材料用量,经济效益明显.
Feasibility of Substituting Cerium-Rich Metal by La-Pr-Ce Alloy in Magnesium Alloy
Institute of Scientific and Technical Information of China (English)
伏思静; 赵平
In magnesium alloy ZM3, using cheap Lanthanum-praseodymium-cerium (LPC) rare earth as a substitute for rich-cerium rare earth was studied. The experimental results show that when the adding amount of LPC is between 2.53% and 3.33%, the tensile strength increases as the adding amount of LPC increases; when the amount of RE is 2.53% and 3.33%, the average tensile strength is 142.35, 153.65 MPa respectively. The results show that LPC rare earth replacing rich Ce rare earth is feasible for the tensile strength of ZM3.
Characteristics of the shark fisheries of Fiji
Glaus, Kerstin B. J.; Irene Adrian-Kalchhauser; Patricia Burkhardt-Holm; White, William T.; Juerg M. Brunnschweiler
Limited information is available on artisanal and subsistence shark fisheries across the Pacific. The aim of this study was to investigate Fiji's inshore fisheries which catch sharks. In January and February 2013, 253 semi-directive interviews were conducted in 117 villages and at local harbours on Viti Levu, Vanua Levu, Taveuni, Ovalau and a number of islands of the Mamanuca and Yasawa archipelagos. Of the 253 interviewees, 81.4% reported to presently catch sharks, and 17.4% declared that th...
Lifescience Database Archive (English)
Full Text Available D05407 Drug Penciclovir (USAN/INN); Denavir (TN) C10H15N5O3 253.1175 253.2578 D0540...TICS FOR TOPICAL USE D06BB Antivirals D06BB06 Penciclovir D05407 Penciclovir (USAN/INN) J ANTIINFECTIVES FOR...s excl. reverse transcriptase inhibitors J05AB13 Penciclovir D05407 Penciclovir (...USAN/INN) USP drug classification [BR:br08302] Antivirals Antiherpetic Agents Penciclovir D05407 Penciclovir... (USAN/INN) Antiinfectives [BR:br08307] Antivirals Anti-HSV agent DNA polymerase inhibitor Purine analogue Penciclo
76 FR 38294 - Oil and Gas and Sulphur Operations in the Outer Continental Shelf-Civil Penalties
... the OCSLA at least once every 3 years (43 U.S.C. 1350). Similarly, a review and adjustment process is required at least once every 4 years for the maximum daily civil penalty assessment allowable under the Oil... Bureau of Ocean Energy Management, Regulation and Enforcement 30 CFR Parts 250 and 253 RIN 1010-AD74...
Whole-Genome Sequence of "Candidatus Liberibacter asiaticus" from a Huanglongbing-Affected Citrus Tree in Central Florida.
Zheng, Z; Sun, X; Deng, X; Chen, J
Here, we report the draft genome sequence of "Candidatus Liberibacter asiaticus" strain FL17, isolated from a huanglongbing (HLB)-affected citrus tree in central Florida. The FL17 genome comprised 1,227,253 bp, with a G+C content of 36.5%, 1,175 predicted open reading frames, and 53 RNA genes. PMID:25792067
Whole-Genome Sequence of "Candidatus Liberibacter asiaticus" from a Huanglongbing-Affected Citrus Tree in Central Florida
Z. Zheng; X. Sun; Deng, X.; J. Chen
Here, we report the draft genome sequence of "Candidatus Liberibacter asiaticus" strain FL17, isolated from a huanglongbing (HLB)-affected citrus tree in central Florida. The FL17 genome comprised 1,227,253 bp, with a G+C content of 36.5%, 1,175 predicted open reading frames, and 53 RNA genes.
Institute of Scientific and Technical Information of China (English)
920743 A prospective trial of hemodilutiontherapy in acute cerebral infarction. DINGMingchen(丁铭臣), et al. Dept Neurol, XuanwuHosp, Capital Instit Med, Beijing, 100053. ChinJ Neurol & Psychiat 1992; 25(3): 146-148. Ninety two patients with acute (<72hours) cerebral infarction involving middle
Investigation of medical board reports of disability due to mental health problems
Directory of Open Access Journals (Sweden)
Mesut Yildiz
Conclusion: We think that this report might be helpful for regulations related to disabled people, and might guide adult psychiatric services for patients who present to medical boards for disability due to mental health problems. [Cukurova Med J 2016; 41(2.000: 253-258
Dicty_cDB: Contig-U10401-1 [Dicty_cDB
Lifescience Database Archive (English)
Full Text Available ntantccntcna 253 Query: 254 tcnatgttangaaccnattagngaattcnttnaattnnnnnnnnaagatcnat...tganttc 313 |||||||||||||||||||||||||||||||||||| |||||||||||||||| Sbjct: 254 tcnatgttangaaccnattagngaattcntt...tatcaatctattccttcaa 932 Query: 254 tcnatgttangaaccnattagngaattcnttnaatt 289 || |||||| ||||| ||||| ||||| || |...ancaatntantccntcna 105 Query: 254 tcnatgttangaaccnattagngaattcnttnaatt 289 |||||||||||||||||||||||||||||||||...||| Sbjct: 104 tcnatgttangaaccnattagngaattcnttnaatt 69 Lambda K H 1.37 0.711 1.31 Matrix: blastn matrix:1 -3
Dicty_cDB: Contig-U13159-1 [Dicty_cDB
Lifescience Database Archive (English)
Full Text Available ntities = 254/254 (100%) Strand = Plus / Plus Query: 13 aaaaagggacttgngagtttgntgatttngatccnaaaccnttnntttgnaa...aactgntg 72 |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 13 aaaaagggacttgngagtttgntgatttngatccna...ttttggtggnaaaaaaggttntgnctactggaaancaagtcaaggngntncna 192 Query: 193 nggccncntnaaangccna...||||| Sbjct: 193 nggccncntnaaangccnatcccctttangaaancnatccntcaggnggngaaaanncna 252 Query: 253 tttntnctagcccc .../235 (97%) Strand = Plus / Plus Query: 13 aaaaagggacttgngagtttgntgatttngatccnaaaccnttnntttgnaaaactgntg 72 ||
Dicty_cDB: Contig-U12608-1 [Dicty_cDB
Lifescience Database Archive (English)
Full Text Available ore = 216 bits (109), Expect = 1e-56 Identities = 248/253 (98%) Strand = Plus / Plus Query: 4 aaaatgctncgagcatgncccagtnaaccnagctaaccn...||||||||||||||||||||||||||||| Sbjct: 4 aaaatgctncgagcatgncccagtnaaccnagctaaccnanaacctgaaagnattgnatt 63 Query...atgatggcgataaaaanananaggatcnaaaatcnactgcttcaaccccccnaggcna 183 ||||||||||||||||||...|||||||||||||||||||||||||||||||||||||||||| Sbjct: 124 ttatgatggcgataaaaanananaggatcnaaaatcnactgcttcaaccccccna...xpect = 2e-05 Identities = 83/105 (79%) Strand = Plus / Plus Query: 150 atcnaaaatcnactgcttcaaccccccnaggcnang
Approaching the Affective Factors of Information Seeking: The Viewpoint of the Information Search Process Model
Savolainen, Reijo
Introduction: The article contributes to the conceptual studies of affective factors in information seeking by examining Kuhlthau's information search process model. Method: This random-digit dial telephone survey of 253 people (75% female) living in a rural, medically under-serviced area of Ontario, Canada, follows-up a previous interview study…
Ten Steps to Complex Learning A New Approach to Instruction and Instructional Design
Kirschner, Paul A.; Van Merriënboer, Jeroen
Kirschner, P. A., & Van Merriënboer, J. J. G. (2008). Ten steps to complex learning: A new approach to instruction and instructional design. In T. L. Good (Ed.), 21st century education: A reference handbook (pp. 244-253). Thousand Oaks, CA: Sage.
Gas dynamic lasers. Citations from the NTIS data base
Carrigan, B.
The citations cover research on kinetic and energy transfer processes, design, optics, nozzles, and performance of gas and chemical lasers relying on gas dynamic effects for lasing enhancement. Diffusion and flow studies specifically applicable to such lasers are also included. This updated bibliography contains 253 citations, 6 of which are new entries to the previous edition.
Professor Perceptions of College Students with Attention Deficit Hyperactivity Disorder
Vance, Teresa Ann; Weyandt, Lisa
Objective: From April to June 2005, the authors investigated professor perceptions of college students with attention deficit hyperactivity disorder (ADHD). Participants: 253 participants completed the ADHD Beliefs Survey-Revised, a 40-question survey measuring professor perceptions of ADHD. Methods: Analysis of variance measured false and…
7 CFR 254.5 - Household eligibility.
... 7 Agriculture 4 2010-01-01 2010-01-01 false Household eligibility. 254.5 Section 254.5 Agriculture Regulations of the Department of Agriculture (Continued) FOOD AND NUTRITION SERVICE, DEPARTMENT OF AGRICULTURE... 253.7. (b) Urban places. No household living in an urban place in Oklahoma shall be eligible for...
ABA and Diverse Cultural and Linguistic Environments: A Welsh Perspective
Jones, E. W.; Hoerger, M.; Hughes, J. C.; Williams, B. M.; Jones, B.; Moseley, Y.; Hughes, D. R.; Prys, D.
Gwynedd Local Education Authority (LEA) in North West Wales, UK, is funding a small-scale autism-specific specialist education service using ABA methodology. The program is available through the medium of Welsh, English or bilingually, depending on the individual needs of the child (Jones and Hoerger in Eur J Behav Anal 10:249-253, "2009").…
Institute of Scientific and Technical Information of China (English)
920748 Magnetic stimulation of motorevoked potential in multiple sclerosis-acomparison with VEP, BAEP and SEP.CUI Liying(崔丽英), et al. Dept Neurol, PUMCHosp, Beijing, 100730. Chin J Neurol & Psy-chiat 1992; 25(3): 130-132. This study consists of 45 patients of MS their
"I work all the time- he just waits for the animals to come back": social impacts of climate changes: a Greenlandic case study
R. van Voorst
Understanding human adaptation to climate changes is one of the most important research issues within the area of global environmental change, accounting for the fact that people worldwide are currently adapting to their changing environment (Adger and Kelly 2000: 253; Smit et al. 2008). The Greenla
48 CFR 53.111 - Contract clause.
... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Contract clause. 53.111... AND FORMS FORMS General 53.111 Contract clause. Contracting officers shall insert the clause at 52.253-1, Computer Generated Forms, in solicitations and contracts that require the contractor to...
Do Verbal Interactions with Infants during Electronic Media Exposure Mitigate Adverse Impacts on Their Language Development as Toddlers?
Mendelsohn, Alan L.; Brockmeyer, Carolyn A.; Dreyer, Benard P.; Fierman, Arthur H.; Berkule-Silberman, Samantha B.; Tomopoulos, Suzy
The goal of this study was to determine whether verbal interactions between mothers and their 6-month-old infants during media exposure ("media verbal interactions") might have direct positive impacts, or mitigate any potential adverse impacts of media exposure, on language development at 14 months. For 253 low-income mother-infant dyads…
24 CFR 5.632 - Utility reimbursements.
... 24 Housing and Urban Development 1 2010-04-01 2010-04-01 false Utility reimbursements. 5.632... Section 8 Project-Based Assistance Family Payment § 5.632 Utility reimbursements. (a) Applicability. This...); (2) A public housing family paying an income-based rent (see § 960.253 of this title)....
China's Ministry of Commerce Set the Tungsten Export Quota for 2007
Institute of Scientific and Technical Information of China (English)
<正>China's ministry of commerce recently set the export quota for tungsten in 2007. According to the ministry's report, China's total tungsten export quota will be 15,400 tons metal content, which is 2.53 per cent less compared to that in 2006.
Pollution caused by ammunition manufacturing. 1964-July 1980 (citations from the NTIS data base). Report for 1964-July 1980
Energy Technology Data Exchange (ETDEWEB)
Cavagnaro, D.M.
The bibliography covers air, water, and solid pollution produced by munition plants. The citations include monitoring, chemical analysis, cost analysis, pollution control techniques, equipment used, and toxicity studies. (This updated bibliography contains 253 citations, 17 of which are new entries to the previous edition.)
Research Intensity Synthesis of Propionic Acid and Vitamin B12 Propionibacteria
Directory of Open Access Journals (Sweden)
Kuznetsova Tatyana
Full Text Available Conducted the selection and breeding of strains of Propionibacterium shermanii ability to synthesize vitamin B12 and propionic acid. Dedicated 9 propionibacteria strains synthesize vitamin B12 (180-1200 mcgr/ml and propionic acid (0,63- 2,53 g/l.
Gclust Server: 201623 [Gclust Server
Lifescience Database Archive (English)
Full Text Available 201623 TET_44.m00181 Cluster Sequences - 253 hypothetical protein chr_0_8254555_44;... no annotation 1 1.00e-99 0.0 11.11 0.0 0.0 0.0 0.0 Show 201623 Cluster ID 201623 Sequence ID TET_44.m00181
The second activating glucokinase mutation (A456V)
DEFF Research Database (Denmark)
Christesen, Henrik B T; Jacobsen, Bendt B; Odili, Stella;
concentration of glucose needed to achieve the half-maximal rate of phosphorylation) from 8.04 (wild-type) to 2.53 mmol/l. The mutant's Hill coefficient was decreased, and its maximal specific activity k(cat) was increased. Mathematical modeling predicted a markedly lowered GSIR threshold of 1.5 mmol...
78 FR 61293 - Endangered and Threatened Wildlife and Plants; Designation of Critical Habitat for Brickellia...
....regulations.gov . FOR FURTHER INFORMATION CONTACT: Larry Williams, Field Supervisor, U.S. Fish and Wildlife... Species Act (published in the Federal Register on July 1, 1994 (59 FR 34271)), the Information Quality Act... in Miami Rock Ridge pinelands (Snyder et al. 1990, p. 253). The shrub/understory layer is...
Indigenous knowledge and processing of Adansonia digitata L. food products in Benin
Chadare, F.J.; Hounhouigan, J.D.; Linnemann, A.R.; Nout, M.J.R.; Boekel, van M.A.J.S.
Indigenous knowledge related to baobab food products was investigated in Benin among 253 food processors from 15 ethnic groups. Descriptive statistics and correspondence analysis (CA) were used for data analysis. The following food categories were identified: dough, gruel, drinks (from pulp); sauces
42 CFR 447.255 - Related information.
... 42 Public Health 4 2010-10-01 2010-10-01 false Related information. 447.255 Section 447.255 Public... Facility Services Payment Rates § 447.255 Related information. The Medicaid agency must submit, with the assurances described in § 447.253(a), the following information: (a) The amount of the estimated...
Effects of Teacher Autonomy Support and Students' Autonomous Motivation on Learning in Physical Education
Shen, Bo; McCaughtry, Nate; Martin, Jeffrey; Fahlman, Mariane
This study applied self-determination theory to investigate the effects of students' autonomous motivation and their perceptions of teacher autonomy support on need satisfaction adjustment, learning achievement, and cardiorespiratory fitness over a 4-month personal conditioning unit. Participants were 253 urban adolescents (121 girls and 132 boys,…
Physiological, biochemical and psychological markers of strenuous training-induced fatigue.
Rietjens, G.J.; Kuipers, H.; Adam, J.; Saris, W.H.M.; Breda, E. van; Hamont, D. van; Keizer, H.A.
The purpose of the study was to investigate whether severe fatigue, possibly leading to overreaching, could be diagnosed at an early stage by a combination of parameters. Seven well-trained male subjects (age [mean +/- SD]: 25.3 +/- 4.7 yr; body mass: 76 +/- 6.6 kg; VO2max: 61.1 +/- 7 ml.kg(-1).min(
Inhibition of ochratoxigenic moulds by Debaryomyces hansenii strains for biopreservation of dry-cured meat products
DEFF Research Database (Denmark)
Andrade, Maria J.; Thorsen, Line; Rodríguez, Alicia;
in co-cultivation batches compared with batches without D. hansenii. The highest level of mould growth inhibition was observed in batches at 0.94 a(w). Ochratoxin A (OTA) production in ham samples was detected by HPLC-MS. Co-culturing of P. nordicum with D. hansenii FHSCC 253H resulted in lower OTA...
77 FR 21841 - Pistachios Grown in California, Arizona, and New Mexico; Decreased Assessment Rate
... FR 60361, Doc. No. AMS-FV-11-0077; FV 983-2 IR], Sec. 983.253 was amended by decreasing the... interim rule, without change, as published in the Federal Register (76 FR 60361, September 29, 2011) will... FR 60361 on September 29, 2011, is adopted as a final rule, without change. Dated: April 6,...
EST Table: DN237714 [KAIKOcDNA[Archive
Lifescience Database Archive (English)
Full Text Available DN237714 EST00840 10/09/29 99 %/253 aa ref|NP_001037309.1| vitellogenin precursor [...s: Precursor dbj|BAA02444.1| vitellogenin precursor [Bombyx mori] dbj|BAA06397.1| vitellogenin [Bombyx mori
EST Table: BB985376 [KAIKOcDNA[Archive
Lifescience Database Archive (English)
Full Text Available BB985376 E_ET_MSV3_04C09_F_0 10/09/28 93 %/253 aa ref|NP_001166288.1| sericin 2 iso...form 2 precursor [Bombyx mori] gb|ADB04958.1| sericin 2 precursor [Bombyx mori] 10/08/28 low homology 10/08/
Presidendi mõjukus avaliku arvamuse silmade läbi / Marti Taru
Taru, Marti, 1970-
Uuringu tulemusena selgus, et avaliku arvamuse silmis eristub president teistest riigijuhtidest just riigimehelikkuse poolest - president peaks olema ametiisik, kes seisab kogu ühiskonna arengu ja heaolu eest, mitte aga ei tegutse kitsaste kildkondade huve esindades. Tabelid. Lisa: Valimi sotsiaal-demograafiline kirjeldus lk. 253-256
De-Schooling Art and Design: Illich Redux
Hardy, Tom
Using Ivan Illich's seminal works, "Deschooling Society" and "Tools for Conviviality" as touchstones, this paper returns to further pursue the thrust of my article in "iJADE" 25.3 (2006), "Domain poisoning: the redundancy of current models of assessment through art," and might be considered as a more radical addendum. The central strand of…
Koolera paneb Haiti valmiduse proovile / Hendrik Vosman
Vosman, Hendrik
Haitis puhkenud koolerapuhang on nõudnud juba 253 inimelu, nakatunute arv ületab 3100 piiri, bakter võib sealsete ebahügieeniliste olude tõttu kaasa tuua teise humanitaarkatastroofi pärast 12. jaanuari maavärinat. Kaart
The Speech-Language Pathologist's Changing Role: Collaboration within the Classroom.
Dohan, Margaret; Schulz, Henry
A survey of 253 Canadian school-based speech-language pathologists (SLPs) found that they use classroom-based approaches primarily for language intervention with early elementary students, judge classroom-based approaches generally successful for intervention with language, articulation, fluency, and voice disorders, and use classroom-based…
77 FR 6573 - Announcement of Funding Awards; Fair Housing Initiatives Program Fiscal Year 2011
.... Education and Outreach/General Comopnent HAP, Inc., 322 Main Street, Springfield, MA Carol Walker, 413-233... Reinvestment Association of North Joel Skillern, 919-667-1557 4 325,000.00 Carolina, 110 E. Geer Street... Center of Washington, 1517 South Lauren Walker, 253-274-9523 10 325,000.00 Fawcett, Suite 250, Tacoma,...
Immigrants from Russia, Ukraine and the Caucasus Region: Differential Drug Use, Infectious Disease, and Related Outcomes
Isralowitz, Richard; Reznik, Alexander; Rawson, Richard A.; Hasson, Albert
This study examined drug use patterns, HIV/AIDS, and related outcomes among former Soviet Union (FSU) immigrants from Russia, Ukraine and the Caucasus mountain region in Israel who reported heroin use. A total of 253 FSU heroin users were interviewed from 2002 to 2007 as part of a large drug use surveillance study in Israel. Individuals were…
Animalien hilkortasuna Ugaz, Ollin eta Asurako ubideetan (Ezkurra/Eratsun, Nafarroa
Directory of Open Access Journals (Sweden)
Full Text Available Se ha contabilizado la mortalidad de vertebrados en dos canales de sendas centrales hidroléctricas de la cuenca del Urumea en Navarra. Durante dos años, en los 2,7 km de Ugaz se han contabilizado 253 vertebrados ahogados y 765 en los 8,35 km de Zumarresta.
24 CFR 213.259a - Premiums-mortgages insured pursuant to section 238(c) of the Act.
... HOUSING COMMISSIONER, DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT MORTGAGE AND LOAN INSURANCE PROGRAMS UNDER NATIONAL HOUSING ACT AND OTHER AUTHORITIES COOPERATIVE HOUSING MORTGAGE INSURANCE Contract Rights.... All of the provisions of §§ 213.253 through 213.259 governing mortgage insurance premiums shall...
32 CFR 37.1005 - What are my general responsibilities concerning the award document?
... requirements. You generally should not incorporate clauses from the Federal Acquisition Regulation (48 CFR parts 1-53) or Defense Federal Acquisition Regulation Supplement (48 CFR parts 201-253), because those... for TIAs or other assistance instruments. (c) Is written in clear and concise language, to...
Aggressive Behavior and Quality of Friendships: Linear and Curvilinear Associations
Fanti, Kostas A.; Brookmeyer, Kathryn A.; Henrich, Christopher C.; Kuperminc, Gabriel P.
The current study investigates linear and curvilinear associations between overt aggressive behavior and the adolescents' reports of the quality of their friendships over time. Moderation by gender was also investigated. The sample consisted of 246 boys and 253 girls from the sixth and seventh grades of a large public middle school. Findings…
Personnel Interviewers' Perceptions of the Importance and Adequacy of Applicants' Communication Skills.
Peterson, Marshalita Sims
Surveys 253 personnel interviewers at midwestern businesses, finding that all respondents identified communication skills as having a major effect on hiring decisions; 90% indicated that communication skills are essential for success; and 60% reported that applicants were prepared with effective communication skills in job interviews. Identifies…
Hole Burning in the Fock Space: from Single to Several Holes
Institute of Scientific and Technical Information of China (English)
B. Baseia; J. M. C. Malbouisson
In our previous papers we have studied the production of a single hole in the photon number distribution of a field state [Phys. Lett. A 240 (1998) 277; 253 (1999) 123]. In this letter we extend the procedure for the controlled creation of an arbitrary number of holes.
Live secondary abdominal pregnancy- by chance!!
Directory of Open Access Journals (Sweden)
Akanksha Sood
Full Text Available Abdominal pregnancy though rare but is a life threatening situation, if not recognized and managed properly. We are hereby presenting a rare successful outcome in a case of ruptured live Secondary Abdominal pregnancy with placental implants over intestines. [Int J Reprod Contracept Obstet Gynecol 2013; 2(2.000: 251-253
Predicting Educational Outcomes and Psychological Well-Being in Adolescents Using Time Attitude Profiles
Andretta, James R.; Worrell, Frank C.; Mello, Zena R.
Using cluster analysis of Adolescent Time Attitude Scale (ATAS) scores in a sample of 300 adolescents ("M" age = 16 years; "SD" = 1.25; 60% male; 41% European American; 25.3% Asian American; 11% African American; 10.3% Latino), the authors identified five time attitude profiles based on positive and negative attitudes toward…
Hurricane Chasers in New Orleans: Latino Immigrants as a Source of a Rapid Response Labor Force
Fussell, Elizabeth
Little is known about the Latino workers who came to New Orleans after Hurricane Katrina to clean up and repair the city. The author uses data from surveys collected at the visits of the Brazilian, Mexican, and Nicaraguan consulates (N = 253) to study the internally mobile immigrants who arrived after Katrina and who anticipate leaving New Orleans…
Attending School and Learning or Repeating and Leaving. A Study about the Determinants of Grade Repetition and Dropout in Primary School in Honduras. Synthesis of the Study = Asistir y Aprender o Repetir y Desertar. Un Estudio sobre los Factores que Contribuyen a la Repitencia en la Escuela Primaria en Honduras. Sintesis del Informe.
McGinn, Noel F.; And Others
This paper synthesizes a study designed to identify the factors that contribute to primary school repetition and dropout in Honduras. Data were collected by record reviews; teacher, student, and parent interviews; and a test of Spanish. The sample included 1,253 students in grades 1 and 3 in 40 schools in rural Honduras. The main findings of the…
Tool, Toy, Telephone, Territory, or Treasure of Information: Elementary School Students' Attitudes toward the Internet
Chou, Chien; Yu, Sen-chi; Chen, Chao-hsiu; Wu, Huan-Chueh
The purposes of this study are to investigate fifth-graders' attitudes toward the Internet based on the 5-T framework (Tool, Toy, Telephone, Territory, and Treasure of Information), and to understand whether gender makes any difference in their attitudes. The data were obtained from 2,253 Taiwan fifth-grade students. Through a confirmatory factor…
Vampirical Stick Pins, Deleuzian Folds, Noir Pastiches and other Wearability Conundrums: Fashion in Film
DEFF Research Database (Denmark)
Langkjær, Michael Alexander
Anmeldelsesartikel (review article) overfjorten bidrag i antologien Fashion in Film, som belyser forskellige sider af forholdet mellem mode og film.Fashion in Film er redigeret af Adrienne Munich (Bloomington: Indiana University Press, 2011, 360 sider, ISBN 978-0-253-22299-2)....
Rare mutations of FGFR2 causing Apert syndrome : identification of the first partial gene deletion, and an Alu element insertion from a new subfamily
Bochukova, E.G.; Roscioli, T.; Hedges, D.J.; Taylor, I.B.; Johnson, D.; David, D.J.; Deininger, P.L.; Wilkie, A.O.
Apert syndrome (AS) is a severe disorder, characterized by craniosynostosis and complex syndactyly of the hands and feet. Two heterozygous gain-of-function substitutions (Ser252Trp and Pro253Arg) in exon IIIa of fibroblast growth factor receptor 2 (FGFR2) are responsible for >98% of cases. Here we d
NRMRL-CIN-1246 Curran*, M.A. Developing a Tool for Environmentally Preferable Purchasing. Environmental Management and Health (Filho, W.L. (Ed.), MCB University Press) 12 (3):244-253 (2001). EPA/600/J-02/238, http://www.emerald-library.com/ft. 12/04/2000 LCA-based guidance wa...
48 CFR 6.302-1 - Only one responsible source and no other supplies or services will satisfy agency requirements.
... 48 Federal Acquisition Regulations System 1 2010-10-01 2010-10-01 false Only one responsible... REQUIREMENTS Other Than Full and Open Competition 6.302-1 Only one responsible source and no other supplies or.... 253(c)(1). (2) When the supplies or services required by the agency are available from only...
DMBT1 is frequently downregulated in well-differentiated gastric carcinoma but more frequently upregulated across various gastric cancer types
DEFF Research Database (Denmark)
Conde, Ana R; Martins, Ana P; Brito, Miguel;
Well-differentiated gastric carcinomas are considered to represent a distinct entity emerging via specific molecular changes different from those found in other gastric carcinoma types. The gene deleted in malignant brain tumours 1 (DMBT1) at 10q25.3-q26.1 codes for a protein presumably involved ...
Lifescience Database Archive (English)
Full Text Available H2|Y2009_RUBXD UPF0042 protein Rxyl_2009 OS=Rubrobacter x... 29 8.8 sp|Q9P802|MIS18_SCHPO Kinetochore protein mis18...RDPAVREAVLAHPDAREFVERVCGLLSFLIPRYA 253 >sp|Q9P802|MIS18_SCHPO Kinetochore protein mis18 OS=Schizosaccharomyces pombe GN=mis18
77 FR 1066 - Information Collection Being Reviewed by the Federal Communications Commission
... respondents; 253,120 responses. Estimated Time per Response: 1.25 hours. Frequency of Response: On occasion... previous burden estimates. FCC Form 601 is a consolidated, multi-part application form, or ``long form... respondents the option to provide a pending File Number for an Antenna Structure Registration...
Measuring Students' Perceptions of Personal and Social Responsibility and the Relationship to Intrinsic Motivation in Urban Physical Education
Li, Weidong; Wright, Paul M.; Rukavina, Paul Bernard; Pickering, Molly
The purpose of the current study was to test the validity and reliability of a two-factor model of the Personal and Social Responsibility Questionnaire (PSRQ) and examine the relationships between perceptions of personal and social responsibility and intrinsic motivation in physical education. Participants were 253 middle school students who…
Gclust Server: 123453 [Gclust Server
Lifescience Database Archive (English)
Full Text Available 123453 PoTR_586742 Cluster Sequences Related Sequences(15) 253 eugene3.02000021 1 1....00e-99 14.29 0.0 0.0 0.0 0.0 0.0 Show 123453 Cluster ID 123453 Sequence ID PoTR_586742 Link to cluster sequ
76 FR 39155 - R.J. Corman Railroad Property, LLC-Acquisition Exemption-NC Railroad, Inc
... Register on April 9, 2010 (75 FR 18,253), and became effective on April 25, 2010. On May 28, 2010, RJC... Surface Transportation Board R.J. Corman Railroad Property, LLC--Acquisition Exemption--NC Railroad, Inc R. J. Corman Railroad Property, LLC (RJC Railroad Property), a Class III rail carrier, filed a...
TrgI, toluene repressed gene I, a novel gene involved in toluene-tolerance in Pseudomonas putida S12
Volkers, R.J.M.; Ballerstedt, H.; Ruijssenaars, H.; Bont, J.A.M. de; Winde, J.H. de; Wery, J.
Pseudomonas putida S12 is well known for its remarkable solvent tolerance. Transcriptomics analysis of this bacterium grown in toluene-containing chemostats revealed the differential expression of 253 genes. As expected, the genes encoding one of the major solvent tolerance mechanisms, the solvent e
Domain Modeling: NP_116174.2 [SAHG[Archive
Lifescience Database Archive (English)
Full Text Available NP_116174.2 chr1 STRUCTURAL BASIS OF THE RESISTANCE OF AN INSECT CARBOXYPEPTIDASE TO PLANT PROTEASE INHIBITO...RS c2c1cb_ chr1/NP_116174.2/NP_116174.2_holo_2-253.pdb psi-blast 45H,48E,143H,144A,216E 95R _ZN 0 ...
77 FR 1642 - Food Distribution Program on Indian Reservations: Income Deductions and Resource Eligibility
...; ] DEPARTMENT OF AGRICULTURE Food and Nutrition Service 7 CFR Part 253 RIN 0584-AE05 Food Distribution Program on Indian Reservations: Income Deductions and Resource Eligibility AGENCY: Food and Nutrition Service, USDA. ACTION: Proposed rule. SUMMARY: This rule proposes to amend regulations for the Food...
75 FR 22027 - Food Distribution Program on Indian Reservations: Amendments Related to the Food, Conservation...
... Food and Nutrition Service 7 CFR Part 253 RIN 0584-AD95 Food Distribution Program on Indian... Service, USDA. ACTION: Proposed rule. SUMMARY: This rule proposes to amend Food Distribution Program on... permanently exclude combat pay from being considered income and eliminate the ] maximum dollar limit of...
78 FR 52827 - Food Distribution Program on Indian Reservations: Income Deductions and Resource Eligibility
... Service 7 CFR Part 253 RIN 0584-AE05 Food Distribution Program on Indian Reservations: Income Deductions... Food Distribution Program on Indian Reservations and the Food Distribution Program for Indian... determining FDPIR eligibility. Second, the final rule will expand the current FDPIR income deduction...
78 FR 79567 - Food Distribution Program on Indian Reservations: Income Deductions and Resource Eligibility...
... Request (ICR). SUMMARY: The final rule entitled Food Distribution Program on Indian Reservations: Income... Food and Nutrition Service 7 CFR Part 253 RIN 0584-AE05 Food Distribution Program on Indian Reservations: Income Deductions and Resource Eligibility; Approval of Information Collection Request...
76 FR 18861 - Food Distribution Program on Indian Reservations: Amendments Related to the Food, Conservation...
... Service 7 CFR Part 253 RIN 0584-AD95 Food Distribution Program on Indian Reservations: Amendments Related...: Final rule. SUMMARY: This rule amends Food Distribution Program on Indian Reservations (FDPIR... excludes combat pay from being considered as income and eliminates the maximum dollar limit of...
Genome-wide association analysis identifies six new loci associated with forced vital capacity
D.W. Loth (Daan); M.S. Artigas; S.A. Gharib (Sina); L.V. Wain (Louise); N. Franceschini (Nora); B. Koch (Beate); T.D. Pottinger (Tess); G.D. Smith; Q. Duan (Qing); C. Oldmeadow (Christopher); M.K. Lee (Mi Kyeong); D.P. Strachan (David); A.L. James (Alan); J.E. Huffman (Jennifer); V. Vitart (Veronique); A. Ramasamy (Adaikalavan); N.J. Wareham (Nick); J. Kaprio (Jaakko); X.-Q. Wang (Xin-Qun); H. Trochet (Holly); M. Kähönen (Mika); C. Flexeder (Claudia); E. Albrecht (Eva); L.M. Lopez (Lorna); B. Thyagarajan (Bharat); A.C. Alves (Alexessander Couto); S. Enroth (Stefan); E. Omenaas (Ernst); P.K. Joshi (Peter); M. Fall (Magnus); A. Viñuela (Ana); L.J. Launer (Lenore); L.R. Loehr (Laura); M. Fornage (Myriam); G. Li (Guo); J.B. Wilk (Jemma); W. Tang (Wenbo); A. Manichaikul (Ani); L. Lahousse (Lies); T.B. Harris (Tamara); K.E. North (Kari); A.R. Rudnicka (Alicja); J. Hui (Jennie); X. Gu (Xiangjun); T. Lumley (Thomas); A.F. Wright (Alan); N. Hastie (Nick); S. Campbell (Susan); R. Kumar (Rajesh); I. Pin (Isabelle); R.A. Scott (Robert); K.H. Pietilainen (Kirsi Hannele); I. Surakka (Ida); Y. Liu (Yongmei); E.G. Holliday (Elizabeth); H. Schulz (Holger); J. Heinrich (Joachim); G. Davies (Gail); J.M. Vonk (Judith); M.K. Wojczynski (Mary ); A. Pouta (Anneli); A. Johansson (Åsa); S.H. Wild (Sarah); E. Ingelsson (Erik); F. Rivadeneira Ramirez (Fernando); H. Völzke (Henry); P.G. Hysi (Pirro); G. Eiriksdottir (Gudny); A.C. Morrison (Alanna); J.I. Rotter (Jerome); W. Gao (Wei); D.S. Postma (Dirkje); W.B. White (Wendy); S.S. Rich (Stephen); A. Hofman (Albert); T. Aspelund (Thor); D. Couper (David); L.J. Smith (Lewis); B.M. Psaty (Bruce); K. Lohman (Kurt); E.G. Burchard (Esteban); A.G. Uitterlinden (André); M. Garcia (Melissa); B.R. Joubert (Bonnie); W.L. McArdle (Wendy); A.W. Musk (Arthur); C.R.W. Hansel (Christian); S.R. Heckbert (Susan); L. Zgaga (Lina); J.B.J. van Meurs (Joyce); P. Navarro (Pau); I. Rudan (Igor); Y.-M. Oh (Yeon-Mok); S. Redline (Susan); D.L. Jarvis (Deborah); J.H. Zhao (Jing); T. Rantanen (Taina); G.T. O'Connor (George); S. Ripatti (Samuli); R.J. Scott (Rodney); S. Karrasch (Stefan); H. Grallert (Harald); N.C. Gaddis (Nathan); J.M. Starr (John); C. Wijmenga (Cisca); R.L. Minster (Ryan); C.W. Lederer (Carsten); J. Pekkanen (Juha); U. Gyllensten (Ulf); H. Campbell (Harry); A.P. Morris (Andrew); S. Gläser (Sven); C.J. Hammond (Christopher); K.M. Burkart (Kristin); J.P. Beilby (John); S.B. Kritchevsky (Stephen); V. Gudnason (Vilmundur); D.B. Hancock (Dana); O.D. Williams (Dale); O. Polasek (Ozren); T. Zemunik (Tatijana); I. Kolcic (Ivana); M.F. Petrini (Marcy); K.T. de Jong (Kim); M. Wjst (Matthias); W.H. Kim (Woo); D.J. Porteous (David J.); G. Scotland (Generation); B.H. Smith (Blair); A. Viljanen (Anne); M. Heliovaara (Markku); J. Attia (John); I. Sayers (Ian); R. Hampel (Regina); C. Gieger (Christian); I.J. Deary (Ian); H.M. Boezen (H. Marike); A.B. Newman (Anne); M.-R. Jarvelin (Marjo-Riitta); J.F. Wilson (James); L. Lind (Lars); B.H.Ch. Stricker (Bruno); A. Teumer (Alexander); T.D. Spector (Timothy); E. Melén (Erik); M.J. Peters (Marjolein); L.A. Lange (Leslie); R.G. Barr (Graham); K.R. Bracke (Ken); F.M. Verhamme (Fien); J. Sung (Joohon); P.S. Hiemstra (Pieter); P.A. Cassano (Patricia); A. Sood (Akshay); C. Hayward (Caroline); J. Dupuis (Josée); I.P. Hall (Ian); G.G. Brusselle (Guy); M.D. Tobin (Martin); S.J. London (Stephanie)
textabstractForced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 individuals from 26 studies and followed up the top associations in
Genome-wide association analysis identifies six new loci associated with forced vital capacity
Loth, Daan W.; Artigas, Maria Soler; Gharib, Sina A.; Wain, Louise V.; Franceschini, Nora; Koch, Beate; Pottinger, Tess D.; Smith, Albert Vernon; Duan, Qing; Oldmeadow, Chris; Lee, Mi Kyeong; Strachan, David P.; James, Alan L.; Huffman, Jennifer E.; Vitart, Veronique; Ramasamy, Adaikalavan; Wareham, Nicholas J.; Kaprio, Jaakko; Wang, Xin-Qun; Trochet, Holly; Kaonen, Mika; Flexeder, Claudia; Albrecht, Eva; Lopez, Lorna M.; de Jong, Kim; Thyagarajan, Bharat; Alves, Alexessander Couto; Enroth, Stefan; Omenaas, Ernst; Joshi, Peter K.; Fall, Tove; Vinuela, Ana; Launer, Lenore J.; Loehr, Laura R.; Fornage, Myriam; Li, Guo; Wik, Jemma B.; Tang, Wenbo; Manichaikul, Ani; Lahousse, Lies; Harris, Tamara B.; North, Kari E.; Rudnicka, Alicja R.; Hui, Jennie; Gu, Xiangjun; Lumley, Thomas; Wright, Alan F.; Hastie, Nicholas D.; Campbell, Susan; Kumar, Rajesh; Pin, Isabelle; Scott, Robert A.; Pietilainen, Kirsi H.; Surakka, Ida; Liu, Yongmei; Holliday, Elizabeth G.; Schulz, Holger; Heinrich, Joachim; Davies, Gail; Vonk, Judith M.; Wojczynski, Mary; Pouta, Anneli; Johansson, Asa; Wild, Sarah H.; Ingelsson, Erik; Rivadeneira, Fernando; Voezke, Henry; Hysi, Pirro G.; Eiriksdottir, Gudny; Morrison, Alanna C.; Rotter, Jerome I.; Gao, Wei; Postma, Dirkje S.; White, Wendy B.; Rich, Stephen S.; Hofman, Albert; Aspelund, Thor; Couper, David; Smith, Lewis J.; Psaty, Bruce M.; Lohman, Kurt; Burchard, Esteban G.; Uitterlinden, Andre G.; Garcia, Melissa; Joubert, Bonnie R.; McArdle, Wendy L.; Musk, A. Bill; Hansel, Nadia; Heckbert, Susan R.; Zgaga, Lina; van Meurs, Joyce B. J.; Navarro, Pau; Rudan, Igor; Oh, Yeon-Mok; Redline, Susan; Jarvis, Deborah L.; Rantanen, Taina; O'Connor, George T.; Ripatti, Samuli; Scott, Rodney J.; Karrasch, Stefan; Grallert, Harald; Gaddis, Nathan C.; Starr, John M.; Wijmenga, Cisca; Minster, Ryan L.; Lederer, David J.; Pekkanen, Juha; Gyllensten, Ulf; Campbe, Harry; Morris, Andrew P.; Glaeser, Sven; Hammond, Christopher J.; Burkart, Kristin M.; Beilby, John; Kritchevsky, Stephen B.; Gucinason, Vilrnundur; Hancock, Dana B.; Williams, Dale; Polasek, Ozren; Zemunik, Tatijana; Kolcic, Ivana; Petrini, Marcy F.; Wjst, Matthias; Kim, Woo Jin; Porteous, David J.; Scotland, Generation; Smith, Blair H.; Villanen, Anne; Heliovaara, Markku; Attia, John R.; Sayers, Ian; Hampel, Regina; Gieger, Christian; Deary, Ian J.; Boezen, Hendrika; Newman, Anne; Jarvelin, Marjo-Riitta; Wilson, James F.; Lind, Lars; Stricker, Bruno H.; Teumer, Alexander; Spector, Timothy D.; Melen, Erik; Peters, Marjolein J.; Lange, Leslie A.; Barr, R. Graham; Bracke, Ken R.; Verhamme, Fien M.; Sung, Joohon; Hiemstra, Pieter S.; Cassano, Patricia A.; Sood, Akshay; Hayward, Caroline; Dupuis, Josee; Hall, Ian P.; Brusselle, Guy G.; Tobin, Martin D.; London, Stephanie J.
Forced vital capacity (FVC), a spirometric measure of pulmonary function, reflects lung volume and is used to diagnose and monitor lung diseases. We performed genome-wide association study meta-analysis of FVC in 52,253 individuals from 26 studies and followed up the top associations in 32,917 addit
QTL Information Table: 720 [Q-TARO
Lifescience Database Archive (English)
Full Text Available DHL Yuefu IRAT109 RM253 RM314 pha Guo, Y., Mu, P., Liu, J., Lu, Y., and Li, Z. (2007). QTL mapping and QxE interactions of grain cook...ing and nutrient qualities in rice under upland and lowland environments. J Genet Genomics 34, 420-428. ...
Doxorubicin Differentially Induces Apoptosis, Expression of Mitochondrial Apoptosis-Related Genes, and Mitochondrial Potential in BCR-ABL1-Expressing Cells Sensitive and Resistant to Imatinib
Directory of Open Access Journals (Sweden)
Ewelina Synowiec
Full Text Available Imatinib resistance is an emerging problem in the therapy of chronic myeloid leukemia (CML. Because imatinib induces apoptosis, which may be coupled with mitochondria and DNA damage is a prototype apoptosis-inducing factor, we hypothesized that imatinib-sensitive and -resistant CML cells might differentially express apoptosis-related mitochondrially encoded genes in response to genotoxic stress. We investigated the effect of doxorubicin (DOX, a DNA-damaging anticancer drug, on apoptosis and the expression of the mitochondrial NADH dehydrogenase 3 (MT-ND3 and cytochrome b (MT-CYB in model CML cells showing imatinib resistance caused by Y253H mutation in the BCR-ABL1 gene (253 or culturing imatinib-sensitive (S cells in increasing concentrations of imatinib (AR. The imatinib-resistant 253 cells displayed higher sensitivity to apoptosis induced by 1 μM DOX and this was confirmed by an increased activity of executioner caspases 3 and 7 in those cells. Native mitochondrial potential was lower in imatinib-resistant cells than in their sensitive counterparts and DOX lowered it. MT-CYB mRNA expression in 253 cells was lower than that in S cells and 0.1 μM DOX kept this relationship. In conclusion, imatinib resistance may be associated with altered mitochondrial response to genotoxic stress, which may be further exploited in CML therapy in patients with imatinib resistance.
Financial Information: Is It Related to Savings and Investing Knowledge and Financial Behavior of Teenagers?
Koonce, Joan C.; Mimura, Yoko; Mauldin, Teresa A.; Rupured, A. Michael; Jordan, Jenny
General linear model procedures were used to investigate the association between financial behavior and sources of financial information, the association between savings and investing knowledge and financial information sources, and the association between financial behavior and savings and investing knowledge. The study participants were 253…
78 FR 39548 - Food Distribution Program on Indian Reservations: Amendments Related to the Food, Conservation...
... Food and Nutrition Service 7 CFR Part 253 RIN 0584-AD95 Food Distribution Program on Indian Reservations: Amendments Related to the Food, Conservation, and Energy Act of 2008; Approval of Information... Reservations: Amendments Related to the Food, Conservation, and Energy Act of 2008 was published on April...
Lifescience Database Archive (English)
Full Text Available ), Gapped BLAST and PSI-BLAST: a new generation of protein database search programs, Nucleic Acids Res. 25:3...eneration of protein database search programs, Nucleic Acids Res. 25:3389-3402. Query= BP914015|Adiantum cap
Lifescience Database Archive (English)
Full Text Available ST: a new generation of protein database search programs, Nucleic Acids Res. 25:3...eng Zhang, Webb Miller, and David J. Lipman (1997), Gapped BLAST and PSI-BLAST: a new generation of protein database search programs
Is bark pH more important than tree species in determining the composition of nitrophytic or acidophytic lichen floras?
Spier, L.; Dobben, van H.F.; Dort, van K.W.
To study the pH preference of epiphytic lichens, the bark pH of Fraxinus, Tilia, Quercus and Ulmus trees in an urban environment was measured using a flat surface electrode. The total number of trees was 253. A survey was made of the lichens in a 40 x 40 cm quadrat surrounding the pH measurement poi
Oversight on Current Status and Administration of Federal Student Assistance Programs. Hearings before the Subcommittee on Postsecondary Education of the Committee on Education and Labor, House of Representatives. Ninety-Seventh Congress, Second Session (January 27, 28 and February 2, 3, and 4, 1982).
Congress of the U.S., Washington, DC. House Committee on Education and Labor.
The management and operations of federal student assistance programs are addressed in hearings before the Committee on Education and Labor. In fiscal year 1981, the Office of Inspector General (OIG), Department of Education (ED) issued 4,811 audit reports on postsecondary education programs. Costs disallowed or questioned amounted to $25.3…
75 FR 52300 - Merchant Marine Act and Magnuson-Stevens Fishery Conservation and Management Act Provisions...
... National Oceanic and Atmospheric Administration 50 CFR Part 253 RIN 0648-AY16 Merchant Marine Act and... Individual Fishing Quota Lending Program Regulations; Correction AGENCY: National Marine Fisheries Service... at 75 FR 24549. Comments must be submitted in writing on or before September 8, 2010. ADDRESSES:...
A NEW FLAVONE GLYCOSIDE, 5-HYDROXY 7,3',4',5'-TETRA-METHOXYFLAVONE 5-O-β-D-XYLOPYRANOSYL (1 → 2)-α-L-RHAMNOPYRANOSIDE FROM BAUHINIA VARIEGATA LINN
Institute of Scientific and Technical Information of China (English)
A new flavone glycoside m.f. C3oH36O15, m.p. 252-253℃, [M]+ 636 (EIMS) was isolated from the acetone soluble fraction of the concentrated 95% ethanolic extract of the seeds of Bauhinia xylopyranosyl-(1→2)-α-L-rhamnopyranoside (1) by various colour reactions, chemical degradations and spectral techniques.
75 FR 24865 - Notice of Contract Proposal (NOCP) for Payments to Eligible Advanced Biofuel Producers
..., Columbia, SC 29201, (803) 253-3150, email@example.com . South Dakota Douglas Roehl, USDA Rural..., firstname.lastname@example.com . Washington Mary Traxler, USDA Rural Development, 1835 Black Lake Blvd. SW., Suite B, Olympia, WA 98512, (360) 704-7762, email@example.com . West Virginia Richard...
Failure to Detect Deaf-Blindness in a Population of People with Intellectual Disability
Fellinger, J.; Holzinger, D.; Dirmhirn, A.; van Dijk, J.; Goldberg, D.
Background: Early identification of deaf-blindness is essential to ensure appropriate management. Previous studies indicate that deaf-blindness is often missed. We aim to discover the extent to which deaf-blindness in people with intellectual disability (ID) is undiagnosed. Method: A survey was made of the 253 residents of an institute offering…
How to Integrate Learning Design into Existing Practice
Janssen, José; Hermans, Henry
This chapter is provided as full text at Springer online (also available here). Janssen, J. & Hermans, H. (2005). How to Integrate Learning Design into Existing Practice. In: Koper, R. & Tattersall, C., Learning Design: A Handbook on Modelling and Delivering Networked Education and Training (pp. 253
7 CFR 1710.303 - Power cost studies-power supply borrowers.
... AND GUARANTEES Long-Range Financial Forecasts § 1710.303 Power cost studies—power supply borrowers. (a... power requirements. This study usually is a separate study but it may be integrated with the financial... conservation alternatives as set forth in §§ 1710.253 and 1710.254; (2) A present-value analysis of the...
Bone and lung tumor response following inhalation of transuranic nitrates
International Nuclear Information System (INIS)
Eight-hundred five rats exposed to transuranic nitrate aerosols developed 111 lung tumors and 24 bone tumors. Results for 239Pu(NO3)4, 238Pu(NO3)4, and 253Es(NO3)3 were similar, and comparable to what has been shown for the more refractory transuranic oxides
Gclust Server: 197164 [Gclust Server
Lifescience Database Archive (English)
Full Text Available 197164 OSA_Os05g0138700 Cluster Sequences - 253 no annotation 1 1.00e-99 14.29 0.0 0.0 0.0 0.0 0.0 Show 1971...64 Cluster ID 197164 Sequence ID OSA_Os05g0138700 Link to cluster sequences Cluster
Defining the role of common variation in the genomic and biological architecture of adult human height
Wood, A.R.; Esko, T.; Yang, J.; Vedantam, S.; Pers, T.H.; Gustafsson, S.; Chu, A.Y.; Estrada, K.; Luan, J.; Kutalik, Z.; Amin, N.; Buchkovich, M.L.; Croteau-Chonka, D.C.; Day, F.R.; Duan, Y.; Fall, T.; Fehrmann, R.; Ferreira, T.; Jackson, A.U.; Karjalainen, J.; Lo, K.S.; Locke, A.E.; Magi, R.; Mihailov, E.; Porcu, E.; Randall, J.C.; Scherag, A.; Vinkhuyzen, A.A.; Westra, H.J.; Winkler, T.W.; Workalemahu, T.; Zhao, J.H.; Absher, D.; Albrecht, E.; Anderson, D.; Baron, J.; Beekman, M.; Demirkan, A.; Ehret, G.B.; Feenstra, B.; Feitosa, M.F.; Fischer, K.; Fraser, R.M.; Goel, A.; Gong, J.; Justice, A.E.; Kanoni, S.; Kleber, M.E.; Kristiansson, K.; Lim, U.; Lotay, V.; Lui, J.C.; Mangino, M.; Leach, I.M.; Medina-Gomez, C.; Nalls, M.A.; Nyholt, D.R.; Palmer, C.D.; Pasko, D.; Pechlivanis, S.; Prokopenko, I.; Ried, J.S.; Ripke, S.; Shungin, D.; Stancakova, A.; Strawbridge, R.J.; Sung, Y.J.; Tanaka, T.; Teumer, A.; Trompet, S.; Laan, S.W. van der; Setten, J. van; Vliet-Ostaptchouk, J.V. Van; Wang, Z.; Yengo, L.; Zhang, W.; Afzal, U.; Arnlov, J.; Arscott, G.M.; Bandinelli, S.; Barrett, A.; Bellis, C.; Bennett, A.J.; Berne, C.; Bluher, M.; Bolton, J.L.; Bottcher, Y.; Boyd, H.A.; Bruinenberg, M.; Buckley, B.M.; Buyske, S.; Caspersen, I.H.; Chines, P.S.; Clarke, R.; Claudi-Boehm, S.; Cooper, M.; Daw, E.W.; Jong, P.A. de; Deelen, J.; Delgado, G.; Vermeulen, S.; Kiemeney, L.A.
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated approximately 2,0
Lifescience Database Archive (English)
Full Text Available _1( DQ673433 |pid:none) Diaphorina citri putative elongati... 66 1e-09 AE013599_2501( AE013599 |pid:none) Dr...17_1( EZ000417 |pid:none) TSA: Culex tarsalis Ctar-253 elong... 68 2e-10 DQ673433
32 CFR 154.18 - Certain positions not necessarily requiring access to classified information.
... for assignment with the Armed Forces overseas (32 CFR part 253). (f) Officials authorized to issue... assignment. (n) Transportation of arms, ammunition and explosives (AA&E). Any DoD military, civilian or... transporting Category I, II or Confidential AA&E shall have been the subject of a favorably adjudicated NAC...
Age and cystatin C in healthy adults : a collaborative study
Odden, Michelle C.; Tager, Ira B.; Gansevoort, Ron T.; Bakker, Stephan J. L.; Katz, Ronit; Fried, Linda F.; Newman, Anne B.; Canada, Robert B.; Harris, Tamara; Sarnak, Mark J.; Siscovick, David; Shlipak, Michael G.
Methods. The authors pooled individual-level cross-sectional data from 18 253 persons aged 28-100 years in four studies: the Cardiovascular Health Study; the Health, Aging and Body Composition Study; the Multi-Ethnic Study of Atherosclerosis and the Prevention of Renal and Vascular End-Stage Disease
Primary school students' strategies in early algebra problem solving supported by an online game
van den Heuvel-Panhuizen, M.H.A.M; Kolovou, A.; Robitzsch, A.
In this study we investigated the role of a dynamic online game on students' early algebra problem solving. In total 253 students from grades 4, 5, and 6 (10–12 years old) used the game at home to solve a sequence of early algebra problems consisting of contextual problems addressing covarying quant
The Relationship between Organizational Support, Work-Family Conflict, and the Job-Life Satisfaction of University Coaches
Dixon, Marlene A.; Sagas, Michael
This study examined the relationship between organizational support, work-family conflict, and job and life satisfaction among coaches. Data from collegiate head coaches with families (N = 253) were gathered through a mailed questionnaire. Results from a series of covariance structure models indicated that a partially mediated model was the best…
Defining the role of common variation in the genomic and biological architecture of adult human height
A.R. Wood (Andrew); T. Esko (Tõnu); J. Yang (Jian); S. Vedantam (Sailaja); T.H. Pers (Tune); S. Gustafsson (Stefan); A.Y. Chu (Audrey Y); K. Estrada Gil (Karol); J. Luan; Z. Kutalik; N. Amin (Najaf); M.L. Buchkovich (Martin); D.C. Croteau-Chonka (Damien); F.R. Day (Felix); Y. Duan (Yanan); M. Fall (Magnus); R.S.N. Fehrmann (Rudolf); T. Ferreira (Teresa); A.U. Jackson (Anne); J. Karjalainen (Juha); K.S. Lo (Ken Sin); A. Locke (Adam); R. Mägi (Reedik); E. Mihailov (Evelin); E. Porcu (Eleonora); J.C. Randall (Joshua); A. Scherag (Andre); A.A.E. Vinkhuyzen (Anna A.); H.J. Westra (Harm-Jan); T.W. Winkler (Thomas W.); T. Workalemahu (Tsegaselassie); J.H. Zhao; D. Absher (Devin); E. Albrecht (Eva); D. Anderson (David); J. Baron (Jeffrey); M. Beekman (Marian); A. Demirkan (Ayşe); G.B. Ehret (Georg); B. Feenstra; M.F. Feitosa (Mary Furlan); K. Fischer (Krista); R.M. Fraser (Ross); A. Goel (Anuj); J. Gong (Jian); A.E. Justice (Anne); S. Kanoni (Stavroula); M.E. Kleber (Marcus); K. Kristiansson; U. Lim (Unhee); V. Lotay (Vaneet); J.C. Lui (Julian C); M. Mangino (Massimo); I.M. Leach (Irene Mateo); M.C. Medina-Gomez (Carolina); M.A. Nalls (Michael); A.S. Dimas (Antigone); C. Palmer (Cameron); D. Pasko (Dorota); S. Pechlivanis (Sonali); I. Prokopenko (Inga); J.S. Ried (Janina); S. Ripke (Stephan); D. Shungin (Dmitry); A. Stancáková (Alena); R.J. Strawbridge (Rona); Y.J. Sung (Yun Ju); T. Tanaka (Toshiko); A. Teumer (Alexander); S. Trompet (Stella); S.W. Van Der Laan (Sander W.); J. van Setten (Jessica); J.V. van Vliet-Ostaptchouk (Jana); Z. Wang (Zhaoming); L. Yengo (Loic); W. Zhang (Weihua); U. Afzal (Uzma); J. Ärnlöv (Johan); G.M. Arscott (Gillian M.); S. Bandinelli (Stefania); A. Barrett (Angela); C. Bellis (Claire); A.J. Bennett (Amanda); C. Berne (Christian); M. Blüher (Matthias); J.L. Bolton (Jennifer); Y. Böttcher (Yvonne); H.A. Boyd; M. Bruinenberg (M.); B.M. Buckley (Brendan M.); S. Buyske (Steven); I.H. Caspersen (Ida H.); P.S. Chines (Peter); R. Clarke (Robert); S. Claudi-Boehm (Simone); M.N. Cooper (Matthew); E.W. Daw (E Warwick); P.A. De Jong (Pim A); J. Deelen (Joris); G. Delgado; J.C. Denny (Josh C); R.A.M. Dhonukshe-Rutten (Rosalie); M. Dimitriou (Maria); A.S.F. Doney (Alex); M. Dörr (Marcus); N. Eklund (Niina); E. Eury (Elodie); L. Folkersen (Lasse); M. Garcia (Melissa); F. Geller (Frank); V. Giedraitis (Vilmantas); A. Go (Attie); H. Grallert (Harald); T.B. Grammer (Tanja B); J. Gräßler (Jürgen); H. Grönberg (Henrik); L.C.P.G.M. de Groot (Lisette); C.J. Groves (Christopher J.); J. Haessler (Jeff); P. Hall (Per); T. Haller (Toomas); G. Hallmans (Göran); M. Hannemann (Mario); C.A. Hartman (Catharina); M. Hassinen (Maija); C. Hayward (Caroline); N.L. Heard-Costa (Nancy); Q. Helmer (Quinta); G. Hemani; A.K. Henders (Anjali); H.L. Hillege (Hans); M.A. Hlatky (Mark); W. Hoffmann (Wolfgang); P. Hoffmann (Per); O.L. Holmen (Oddgeir); J.J. Houwing-Duistermaat (Jeanine); T. Illig (Thomas); A. Isaacs (Aaron); A.L. James (Alan); J. Jeff (Janina); B. Johansen (Berit); A. Johansson (Åsa); G.J. Jolley (Jason); T. Juliusdottir (Thorhildur); M.J. Junttila (Juhani); M.M.L. Kho (Marcia); L. Kinnunen (Leena); N. Klopp (Norman); T. Kocher; W. Kratzer (Wolfgang); P. Lichtner (Peter); L. Lind (Lars); J. Lindström (Jaana); S. Lobbens (Stéphane); M. Lorentzon (Mattias); Y. Lu (Yingchang); V. Lyssenko (Valeriya); P.K. Magnusson (Patrik); A. Mahajan (Anubha); M. Maillard (Marc); W.L. McArdle (Wendy); C.A. McKenzie (Colin A.); S. McLachlan (Stela); P.J. McLaren (Paul J); C. Menni (Cristina); S. Merger (Sigrun); L. Milani (Lili); A. Moayyeri (Alireza); K.L. Monda (Keri); M.A. Morken (Mario); G. Müller (Gabriele); M. Müller-Nurasyid (Martina); A.W. Musk (Arthur); N. Narisu (Narisu); M. Nauck (Matthias); I.M. Nolte (Ilja M.); M.M. Nöthen (Markus); L. Oozageer (Laticia); S. Pilz (Stefan); N.W. Rayner (Nigel William); F. Renström (Frida); N.R. Robertson (Neil R.); L.M. Rose (Lynda M.); R. Roussel (Ronan); S. Sanna (Serena); H. Scharnagl (Hubert); S. Scholtens (Salome); F.R. Schumacher (Fredrick R); H. Schunkert (Heribert); R.A. Scott (Robert); J.S. Sehmi (Joban); T. Seufferlein (Thomas); J. Shi (Jianxin); K. Silventoinen (Karri); J.H. Smit (Johannes H.); G.D. Smith; J. Smolonska (Joanna); A. Stanton (Alice); K. Stirrups (Kathy); D.J. Stott (David J); H.M. Stringham (Heather); J. Sundstrom (Johan); M. Swertz (Morris); A.C. Syvanen; B. Tayo (Bamidele); G. Thorleifsson (Gudmar); J.P. Tyrer (Jonathan); S. Van Dijk (Suzanne); N.M. van Schoor (Natasja); N. van der Velde (Nathalie); D. van Heemst (Diana); F.V.A. Van Oort (Floor V A); S.H.H.M. Vermeulen (Sita); N. Verweij (Niek); J.M. Vonk (Judith M); L. Waite (Lindsay); M. Waldenberger (Melanie); R. Wennauer (Roman); L.R. Wilkens (Lynne R.); C. Willenborg (Christina); T. Wilsgaard (Tom); M.K. Wojczynski (Mary ); A. Wong (Andrew); A. Wright (Alan); Q. Zhang (Qunyuan); D. Arveiler (Dominique); S.J.L. Bakker (Stephan J L); J. Beilby (John); R.N. Bergman (Richard); S.M. Bergmann (Sven); R. Biffar; J. Blangero (John); D.I. Boomsma (Dorret); S.R. Bornstein (Stefan R.); P. Bovet (Pascal); P. Brambilla (Paolo); M.J. Brown (Morris); H. Campbell (Harry); M. Caulfield (Mark); A. Chakravarti (Aravinda); F.S. Collins (Francis); F.S. Collins (Francis); D.C. Crawford (Dana); L.A. Cupples (Adrienne); J. Danesh (John); U. de Faire (Ulf); H.M. den Ruijter (Hester ); R. Erbel (Raimund); J. Erdmann (Jeanette); J. Eriksson; M. Farrall (Martin); E. Ferrannini (Ele); J. Ferrieres (Jean); I. Ford; N.G. Forouhi (Nita); T. Forrester (Terrence); R.T. Gansevoort (Ron); P.V. Gejman (Pablo); C. Gieger (Christian); A. Golay (Alain); R.F. Gottesman (Rebecca); V. Gudnason (Vilmundur); U. Gyllensten (Ulf); D.W. Haas (David W); A.S. Hall (Alistair); T.B. Harris (Tamara B.); A.T. Hattersley (Andrew); A.C. Heath (Andrew C); C. Hengstenberg (Christian); A.A. Hicks (Andrew); L.A. Hindorff (Lucia A); A. Hingorani (Aroon); A. Hofman (Albert); G.K. Hovingh (Kees); S.E. Humphries (Steve E.); S.C. Hunt (Steven); E. Hypponen (Elina); K.B. Jacobs (Kevin); M.-R. Jarvelin (Marjo-Riitta); P. Jousilahti (Pekka); A. Jula (Antti); J. Kaprio (Jaakko); J.J.P. Kastelein (John); M.H. Kayser (Manfred); F. Kee (Frank); S. Keinanen-Kiukaanniemi (Sirkka); L.A.L.M. Kiemeney (Bart); J.S. Kooner (Jaspal S.); C. Kooperberg (Charles); S. Koskinen (Seppo); P. Kovacs (Peter); A. Kraja (Aldi); M. Kumari (Meena); J. Kuusisto (Johanna); T.A. Lakka (Timo); C. Langenberg (Claudia); L. Le Marchand (Loic); T. Lehtimäki (Terho); S. Lupoli (Sara); P.A. Madden; S. Männistö (Satu); P. Manunta (Paolo); A. Marette (Andre'); T.C. Matise (Tara C.); B. McKnight (Barbara); T. Meitinger (Thomas); F.L. Moll (Frans); G.W. Montgomery (Grant W.); A.D. Morris (Andrew); A.P. Morris (Andrew); J.C. Murray (Jeffrey); M. Nelis (Mari); C. Ohlsson (Claes); A.J. Oldehinkel (Albertine); K.K. Ong (Ken K.); W.H. Ouwehand (Willem); G. Pasterkamp (Gerard); A. Peters (Annette); P.P. Pramstaller (Peter Paul); J.F. Price (Jackie F.); L. Qi (Lu); O. Raitakari (Olli); T. Rankinen (Tuomo); D.C. Rao (Dabeeru C.); T.K. Rice (Treva K.); M.D. Ritchie (Marylyn D.); I. Rudan (Igor); V. Salomaa (Veikko); N.J. Samani (Nilesh); J. Saramies (Jouko); M.A. Sarzynski (Mark A.); P.E.H. Schwarz (Peter E. H.); S. Sebert (Sylvain); P. Sever (Peter); A.R. Shuldiner (Alan); J. Sinisalo (Juha); V. Steinthorsdottir (Valgerdur); R.P. Stolk; J.-C. Tardif (Jean-Claude); A. Tönjes (Anke); A. Tremblay (Angelo); E. Tremoli (Elena); J. Virtamo (Jarmo); M.-C. Vohl (Marie-Claude); P. Amouyel (Philippe); F.W. Asselbergs (Folkert W.); T.L. Assimes (Themistocles); M. Bochud (Murielle); B.O. Boehm (Bernhard); E.A. Boerwinkle (Eric); E.P. Bottinger (Erwin P.); C. Bouchard (Claude); S. Cauchi (Stéphane); J.C. Chambers (John C.); S.J. Chanock (Stephen); R.S. Cooper (Richard S.); P.I.W. de Bakker (Paul); G.V. Dedoussis (George); L. Ferrucci (Luigi); P.W. Franks; P. Froguel (Philippe); L. Groop (Leif); C.A. Haiman (Christopher); A. Hamsten (Anders); M.G. Hayes (M. Geoffrey); J. Hui (Jennie); D. Hunter (David); K. Hveem (Kristian); J.W. Jukema (Jan Wouter); R.C. Kaplan (Robert); M. Kivimaki (Mika); D. Kuh (Diana); M. Laakso (Markku); Y. Liu (Yongmei); N.G. Martin (Nicholas); W. März (Winfried); M. Melbye (Mads); S. Moebus (Susanne); P. Munroe (Patricia); I. Njølstad (Inger); B.A. Oostra (Ben); C.N.A. Palmer (Colin); N.L. Pedersen (Nancy L.); M. Perola (Markus); L. Perusse (Louis); U. Peters (Ulrike); J.E. Powell (Joseph); C. Power (Christine); T. Quertermous (Thomas); R. Rauramaa (Rainer); E. Reinmaa (Eva); P.M. Ridker (Paul); F. Rivadeneira Ramirez (Fernando); J.I. Rotter (Jerome I.); T. Saaristo (Timo); D. Saleheen; D. Schlessinger (David); P.E. Slagboom (P Eline); H. Snieder (Harold); T.D. Spector (Timothy); K. Strauch (Konstantin); M. Stumvoll (Michael); J. Tuomilehto (Jaakko); M. Uusitupa (Matti); P. van der Harst (Pim); H. Völzke (Henry); M. Walker (Mark); N.J. Wareham (Nick); H. Watkins (Hugh); H.E. Wichmann (Heinz Erich); J.F. Wilson (James F); P. Zanen (Pieter); P. Deloukas (Panagiotis); I.M. Heid (Iris); C.M. Lindgren (Cecilia); K.L. Mohlke (Karen); E.K. Speliotes (Elizabeth); U. Thorsteinsdottir (Unnur); I. Barroso (Inês); C.S. Fox (Caroline S.); K.E. North (Kari); D.P. Strachan (David P.); J.S. Beckmann (Jacques); S.I. Berndt (Sonja); M. Boehnke (Michael); I.B. Borecki (Ingrid); M.I. McCarthy (Mark); A. Metspalu (Andres); J-A. Zwart (John-Anker); A.G. Uitterlinden (André); C.M. van Duijn (Cock); L. Franke (Lude); C.J. Willer (Cristen); A. Price (Alkes); G. Lettre (Guillaume); R.J.F. Loos (Ruth); M.N. Weedon (Michael); E. Ingelsson (Erik); J.R. O´Connell; G.R. Abecasis (Gonçalo); D.I. Chasman (Daniel); M.E. Goddard (Michael); P.M. Visscher (Peter); J.N. Hirschhorn (Joel); T.M. Frayling (Timothy)
textabstractUsing genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated 1/42,
Defining the role of common variation in the genomic and biological architecture of adult human height
Wood, Andrew R.; Esko, Tonu; Yang, Jian; Vedantam, Sailaja; Pers, Tune H.; Gustafsson, Stefan; Chun, Audrey Y.; Estrada, Karol; Luan, Jian'an; Kutalik, Zoltan; Amin, Najaf; Buchkovich, Martin L.; Croteau-Chonka, Damien C.; Day, Felix R.; Duan, Yanan; Fall, Tove; Fehrmann, Rudolf; Ferreira, Teresa; Jackson, Anne U.; Karjalainen, Juha; Lo, Ken Sin; Locke, Adam E.; Maegi, Reedik; Mihailov, Evelin; Porcu, Eleonora; Randall, Joshua C.; Scherag, Andre; Vinkhuyzen, Anna A. E.; Westra, Harm-Jan; Winkler, Thomas W.; Workalemahu, Tsegaselassie; Zhao, Jing Hua; Absher, Devin; Albrecht, Eva; Anderson, Denise; Baron, Jeffrey; Beekman, Marian; Demirkan, Ayse; Ehret, Georg B.; Feenstra, Bjarke; Feitosa, Mary F.; Fischer, Krista; Fraser, Ross M.; Goel, Anuj; Gong, Jian; Justice, Anne E.; Kanoni, Stavroula; Kleber, Marcus E.; Kristiansson, Kati; Lim, Unhee; Lotay, Vaneet; Lui, Julian C.; Mangino, Massimo; Mateo Leach, Irene; Medina-Gomez, Carolina; Nalls, Michael A.; Nyholt, Dale R.; Palmer, Cameron D.; Pasko, Dorota; Pechlivanis, Sonali; Prokopenko, Inga; Ried, Janina S.; Ripke, Stephan; Shungin, Dmitry; Stancakova, Alena; Strawbridge, Rona J.; Sung, Yun Ju; Tanaka, Toshiko; Teumer, Alexander; Trompet, Stella; van der Laan, Sander W.; van Setten, Jessica; Van Vliet-Ostaptchouk, Jana V.; Wang, Zhaoming; Yengo, Loic; Zhang, Weihua; Afzal, Uzma; Arnloev, Johan; Arscott, Gillian M.; Bandinelli, Stefania; Barrett, Amy; Bellis, Claire; Bennett, Amanda J.; Berne, Christian; Blueher, Matthias; Bolton, Jennifer L.; Boettcher, Yvonne; Boyd, Heather A.; Bruinenberg, Marcel; Buckley, Brendan M.; Buyske, Steven; Caspersen, Ida H.; Chines, Peter S.; Clarke, Robert; Claudi-Boehm, Simone; Cooper, Matthew; Daw, E. Warwick; De Jong, Pim A.; Deelen, Joris; Delgado, Graciela; Denny, Josh C.; Dhonukshe-Rutten, Rosalie; Dimitriou, Maria; Doney, Alex S. F.; Doerr, Marcus; Eklund, Niina; Eury, Elodie; Folkersen, Lasse; Garcia, Melissa E.; Geller, Frank; Giedraitis, Vilmantas; Go, Alan S.; Grallert, Harald; Grammer, Tanja B.; Graessler, Juergen; Groenberg, Henrik; de Groot, Lisette C. P. G. M.; Groves, Christopher J.; Haessler, Jeffrey; Hall, Per; Haller, Toomas; Hallmans, Goran; Hannemann, Anke; Hartman, Catharina A.; Hassinen, Maija; Hayward, Caroline; Heard-Costa, Nancy L.; Helmer, Quinta; Hemani, Gibran; Henders, Anjali K.; Hillege, Hans L.; Hlatky, Mark A.; Hoffmann, Wolfgang; Hoffmann, Per; Holmen, Oddgeir; Houwing-Duistermaat, Jeanine J.; Illig, Thomas; Isaacs, Aaron; James, Alan L.; Jeff, Janina; Johansen, Bent; Johansson, Asa; Jolley, Jennifer; Juliusdottir, Thorhildur; Junttila, Juhani; Kho, Abel N.; Kinnunen, Leena; Klopp, Norman; Kocher, Thomas; Kratzer, Wolfgang; Lichtner, Peter; Lind, Lars; Lindstroem, Jaana; Lobbens, Stephane; Lorentzon, Mattias; Lu, Yingchang; Lyssenko, Valeriya; Magnusson, Patrik K. E.; Mahajan, Anubha; Maillard, Marc; McArdle, Wendy L.; McKenzie, Colin A.; McLachlan, Stela; McLaren, Paul J.; Menni, Cristina; Merger, Sigrun; Milani, Lili; Moayyeri, Alireza; Monda, Keri L.; Morken, Mario A.; Mueller, Gabriele; Mueller-Nurasyid, Martina; Musk, Arthur W.; Narisu, Narisu; Nauck, Matthias; Nolte, Ilja M.; Noethen, Markus M.; Oozageer, Laticia; Pilz, Stefan; Rayner, Nigel W.; Renstrom, Frida; Robertson, Neil R.; Rose, Lynda M.; Roussel, Ronan; Sanna, Serena; Scharnagl, Hubert; Scholtens, Salome; Schumacher, Fredrick R.; Schunkert, Heribert; Scott, Robert A.; Sehmi, Joban; Seufferlein, Thomas; Shin, Jianxin; Silventoinen, Karri; Smit, Johannes H.; Smith, Albert Vernon; Smolonska, Joanna; Stanton, Alice V.; Stirrups, Kathleen; Stott, David J.; Stringham, Heather M.; Sundstrom, Johan; Swertz, Morris A.; Syvanen, Ann-Christine; Tayo, Bamidele O.; Thorleifsson, Gudmar; Tyrer, Jonathan P.; van Dijk, Suzanne; van Schoor, Natasja M.; van der Velde, Nathalie; van Heemst, Diana; van Oort, Floor V. A.; Vermeulen, Sita H.; Verweij, Niek; Vonk, Judith M.; Waite, Lindsay L.; Waldenberger, Melanie; Wennauer, Roman; Wilkens, Lynne R.; Willenborg, Christina; Wilsgaard, Tom; Wojczynski, Mary K.; Wong, Andrew; Wright, Alan F.; Zhang, Qunyuan; Arveiler, Dominique; Bakker, Stephan J. L.; Beilby, John; Bergman, Richard N.; Bergmann, Sven; Biffar, Reiner; Blangero, John; Boomsma, Dorret I.; Bornstein, Stefan R.; Bovet, Pascal; Brambilla, Paolo; Brown, Morris J.; Campbell, Harry; Caulfield, Mark J.; Chakravarti, Aravinda; Collins, Rory; Collins, Francis S.; Crawford, Dana C.; Cupples, L. Adrienne; Danesh, John; de Faire, Ulf; den Ruijter, Hester M.; Erbel, Raimund; Erdmann, Jeanette; Eriksson, Johan G.; Farrall, Martin; Ferrannini, Ele; Ferrieres, Jean; Ford, Ian; Forouhi, Nita G.; Forrester, Terrence; Gansevoort, Ron T.; Gejman, Pablo V.; Gieger, Christian; Golay, Alain; Gottesman, Omri; Gudnason, Vilmundur; Gyllensten, Ulf; Haas, David W.; Hall, Alistair S.; Harris, Tamara B.; Hattersley, Andrew T.; Heath, Andrew C.; Hengstenberg, Christian; Hicks, Andrew A.; Hindorff, Lucia A.; Hingorani, Aroon D.; Hofman, Albert; Hovingh, G. Kees; Humphries, Steve E.; Hunt, Steven C.; Hypponen, Elina; Jacobs, Kevin B.; Jarvelin, Marjo-Riitta; Jousilahti, Pekka; Jula, Antti M.; Kaprio, Jaakko; Kastelein, John J. P.; Kayser, Manfred; Kee, Frank; Keinanen-Kiukaanniemi, Sirkka M.; Kiemeney, Lambertus A.; Kooner, Jaspal S.; Kooperberg, Charles; Koskinen, Seppo; Kovacs, Peter; Kraja, Aldi T.; Kumari, Meena; Kuusisto, Johanna; Lakka, Timo A.; Langenberg, Claudia; Le Marchand, Loic; Lehtimaki, Terho; Lupoli, Sara; Madden, Pamela A. F.; Mannisto, Satu; Manunta, Paolo; Marette, Andre; Matise, Tara C.; McKnight, Barbara; Meitinger, Thomas; Moll, Frans L.; Montgomery, Grant W.; Morris, Andrew D.; Morris, Andrew P.; Murray, Jeffrey C.; Nelis, Mari; Ohlsson, Claes; Oldehinkel, Albertine J.; Ong, Ken K.; Ouwehand, Willem H.; Pasterkamp, Gerard; Peters, Annette; Pramstaller, Peter P.; Price, Jackie F.; Qi, Lu; Raitakari, Olli T.; Rankinen, Tuomo; Rao, D. C.; Rice, Treva K.; Ritchie, Marylyn; Rudan, Igor; Salomaa, Veikko; Samani, Nilesh J.; Saramies, Jouko; Sarzynski, Mark A.; Schwarz, Peter E. H.; Sebert, Sylvain; Sever, Peter; Shuldiner, Alan R.; Sinisalo, Juha; Steinthorsdottir, Valgerdur; Stolk, Ronald P.; Tardif, Jean-Claude; Toenjes, Anke; Tremblay, Angelo; Tremoli, Elena; Virtamo, Jarmo; Vohl, Marie-Claude; Amouyel, Philippe; Asselbergs, Folkert W.; Assimes, Themistocles L.; Bochud, Murielle; Boehm, Bernhard O.; Boerwinkle, Eric; Bottinger, Erwin P.; Bouchard, Claude; Cauchi, Stephane; Chambers, John C.; Chanock, Stephen J.; Cooper, Richard S.; de Bakker, Paul I. W.; Dedoussis, George; Ferrucci, Luigi; Franks, Paul W.; Froguel, Philippe; Groop, Leif C.; Haiman, Christopher A.; Hamsten, Anders; Hayes, M. Geoffrey; Hui, Jennie; Hunter, David J.; Hveem, Kristian; Jukema, J. Wouter; Kaplan, Robert C.; Kivimaki, Mika; Kuh, Diana; Laakso, Markku; Liu, Yongmei; Martin, Nicholas G.; Maerz, Winfried; Melbye, Mads; Moebus, Susanne; Munroe, Patricia B.; Njolstad, Inger; Oostra, Ben A.; Palmer, Colin N. A.; Pedersen, Nancy L.; Perola, Markus; Perusse, Louis; Peters, Ulrike; Powell, Joseph E.; Power, Chris; Quertermous, Thomas; Rauramaa, Rainer; Reinmaa, Eva; Ridker, Paul M.; Rivadeneira, Fernando; Rotter, Jerome I.; Saaristo, Timo E.; Saleheen, Danish; Schlessinger, David; Slagboom, P. Eline; Snieder, Harold; Spector, Tim D.; Strauch, Konstantin; Stumvoll, Michael; Tuomilehto, Jaakko; Uusitupa, Matti; van der Harst, Pim; Voelzke, Henry; Walker, Mark; Wareham, Nicholas J.; Watkins, Hugh; Wichmann, H-Erich; Wilson, James F.; Zanen, Pieter; Deloukas, Panos; Heid, Iris M.; Lindgren, Cecilia M.; Mohlke, Karen L.; Speliotes, Elizabeth K.; Thorsteinsdottir, Unnur; Barroso, Ines; Fox, Caroline S.; North, Kari E.; Strachan, David P.; Beckmann, Jacques S.; Berndt, Sonja I.; Boehnke, Michael; Borecki, Ingrid B.; McCarthy, Mark I.; Metspalu, Andres; Stefansson, Kari; Uitterlinden, Andre G.; van Duijn, Cornelia M.; Franke, Lude; Willer, Cristen J.; Price, Alkes L.; Lettre, Guillaume; Loos, Ruth J. F.; Weedon, Michael N.; Ingelsson, Erik; O'Connell, Jeffrey R.; Abecasis, Goncalo R.; Chasman, Daniel I.; Goddard, Michael E.; Visscher, Peter M.; Hirschhorn, Joel N.; Frayling, Timothy M.
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated similar to 2,000,
Para estimular a escrita científica
Directory of Open Access Journals (Sweden)
Elimar Nascimento
Full Text Available Howard S. Becker. Truques da escrita. Para começar e terminar teses, livros e artigos. São Paulo: Zahar, 2014. 253 p. Tradução de Denise Bottmann; revisão de Karina Kuschnir. ISBN 978-85-378-1394-2.
Inter-annual variations in wave characteristics off Ratnagiri, Northeast Arabian Sea
Digital Repository Service at National Institute of Oceanography (India)
Johnson, G.; SanilKumar, V.; Singh, J.
coastal erosion and hence we have examined the events lasting more than 5 h with different threshold limits of wave height (2.5,3 and 3.5 m). Average Hs during the monsoon is around 3 times that in non-monsoon period. Average of the maximum wave spectral...
Offending Profiles of Individuals with Autism Spectrum Disorder: A Study of All Individuals with Autism Spectrum Disorder Examined by the Forensic Psychiatric Service in Norway between 2000 and 2010
Helverschou, Sissel Berge; Rasmussen, Kirsten; Steindal, Kari; Søndanaa, Erik; Nilsson, Britta; Nøttestad, Jim Aage
This study examined the characteristics of adults with autism spectrum disorder who have undergone a forensic examination and explored any relationships between the diagnosis and the offence. The reports described 41 men and 7 women. The autism spectrum disorder was diagnosed late (mean age: 25.3?years), and 22 of the 48 cases were diagnosed with…
Effects of iron and multimicronutrient supplementation on geophagy
DEFF Research Database (Denmark)
Nchito, Mbiko; Geissler, P Wenzel; Mubila, Likezo;
/l, geophageous children had significantly higher prevalence (53.7 vs. 30.6%, P = 0.024) of Ascaris lumbricoides infection than non-geophageous. The prevalence of geophagy (74.4 to 51.6%) and the intake of earth (25.3 to 15.0 g/day) declined (P = 0.001 and P
Mõne läänemeresoome sufiksi taustast / Ago Künnap
Künnap, Ago, 1941-
Vastukaja artiklile: Grünthal, Riho. The Mordvinic languages between bush and tree : a historical reappraisal // Sámit, sánit, sátnehámit : riepmočála Pekka Sammallahtii miessemánu 21. beaivve 2007. Helsinki : Suomalais-Ugrilainen Seura, 2007. (Suomalais-Ugrilaisen Seuran toimituksia ; 253)
In the Mood for Risk? A Random-Assignment Experiment Addressing the Effects of Moods on Risk Preferences
T. Treffers (Theresa (Michl)); Ph.D. Koellinger (Philipp); A.O. Picot (Arnold)
textabstractRecent discussions in decision sciences and behavioral economics stress the potential impact of affect on decision outcomes. In the present study, we conducted random-assignment experiments (N = 253) to investigate whether affect can cause temporary fluctuations in risk preferences. In p
Daily and Momentary Mood and Stress Are Associated with Binge Eating and Vomiting in Bulimia Nervosa Patients in the Natural Environment
Smyth, Joshua M.; Wonderlich, Stephen A.; Heron, Kristin E.; Sliwinski, Martin J.; Crosby, Ross D.; Mitchell, James E.; Engel, Scott G.
The relation of mood and stress to binge eating and vomiting in the natural environments of patients with bulimia nervosa (BN) was examined using real-time data collection. Women (n = 131; mean age = 25.3 years) with BN carried a palmtop computer for 2 weeks and completed ratings of positive affect (PA), negative affect (NA), anger/hostility (AH),…
76 FR 27895 - Safety Zone; 2011 Memorial Day Tribute Fireworks, Lake Charlevoix, Boyne City, MI
... rule, call or e-mail MST1 Aaron Woof, U.S. Coast Guard, Sector Sault Sainte Marie, telephone 906-253-2423, e-mail at firstname.lastname@example.com . If you have questions on viewing the docket, call Renee...
Lifescience Database Archive (English)
Full Text Available Putative developmental protein OS=Nicotia... 253 4e-66 tr|Q9SSM4|Q9SSM4_ARATH Highly similar to developmenta...+V SLM QVAD++GLEVS GLP Sbjct: 122 EQQFVNMEVQAEFMESSMAGSTSLSTPEDQVNSLMHQVADDYGLEVSVGLP 172 >tr|Q9SSM4|Q9SSM4_ARATH Highly
76 FR 23109 - Enhancing Airline Passenger Protections
... majority of the provisions in that rule took effect on April 29, 2010. See 74 FR 68983 (December 30, 2009... rulemaking (NPRM), 75 FR 32318, in which it addressed the following areas: (1) Contingency plans for lengthy... April 25, 2011 Part IV Department of Transportation 14 CFR Parts 244, 250, 253 Et al. Enhancing...
75 FR 45562 - Enhancing Airline Passenger Protections
... Privacy Act statement in the Federal Register published on April 11, 2000 (65 FR 19477-78), or you may... travel for persons with peanut allergies. See 75 FR 32318 (June 8, 2010). Comments on the matters... Office of the Secretary 14 CFR Parts 234, 244, 250, 253, 259, and 399 RIN No. 2105-AD92 Enhancing...
76 FR 45181 - Enhancing Airline Passenger Protections: Limited Delay of Effective Date for Certain Provisions
... Federal Register (76 FR 23110), titled ``Enhancing Airline Passenger Protections,'' containing many new... July 28, 2011. The effective date of the final rule published at 76 FR 23110, April 25, 2011, continues... Office of the Secretary 14 CFR Parts 244, 250, 253, 259 and 399 RIN No. 2105-AD92 Enhancing...
77 FR 37887 - Notice of Commission Meeting and Public Hearing
... the dockets may be examined at the Commission's offices. Please contact William Muszynski at 609-883.... The WWTP will continue to discharge to Turner Brook at River Mile 253.64--14.52-- 7.05--2.27 (Delaware River--Neversink River--Bush Kill--Turner Brook) via Outfall No. 001. The WWTP is located within...
The International Diversification of Banks and the Value of their Cross-Border M&A Advice
de Jong, A.; Ongena, S.; van der Poel, M.
This paper investigates the effects of international diversification of banks on the value of their M&A advice. We study bidder returns to 1,253 cross-border M&A announcements. We find that acquirers engaging a more internationally diversified financial advisor generate lower excess returns. Acquire
Deciding the Future: A Forecast of Responsibilities of Secondary Teachers of English, 1970-2000 AD.
Farrell, Edmund J.
This document is a slightly revised version of author's Ph.D. Dissertation, "A Forecast of Responsibilities of Secondary Teachers of English 1970-2000 A.D., with Implications for Teacher Education" (ED 049 253). A study in two parts, Part I presents the need for future planning in education; discusses briefly methodologies for forecasting the…
Psychological Well-Being and Social Participation Assessment in Visually Impaired Subjects Playing Torball: A Controlled Study
Di Cagno, A.; Iuliano, E.; Aquino, G.; Fiorilli, G.; Battaglia, C.; Giombini, A.; Calcagno, G.
The aim of this study was to evaluate the differences in psychological well-being, symptomatic psychological disorders and social participation, between blind Torball players and non-players. Thirty blind male participants were recruited, 17 Torball players (aged 36.27 plus or minus 3.46) and 13 non-players (aged 34.80 plus or minus 2.53), and…
Counterterrorism On the Wrong Track
Institute of Scientific and Technical Information of China (English)
@@ Umar Farouk Abdulmutallab's attempt at bombing Northwest Airlines Flight 253 on Christmas Day 2009 certainly rekindled Americans' interest in terrorism and security. Until recendy, security issues for many citi-zens seemed to focus on complaints about the endless lines and burdensome procedures at airports.
An Exploration of the Common Content Knowledge of High School Mathematics Teachers
Bansilal, Sarah; Brijlall, Deonarain; Mkhwanazi, Thokozani
Many studies point to the problem of poor mathematics content knowledge of mathematics teachers in South Africa. The purpose of this study was to investigate teachers' knowledge of the mathematics they are themselves teaching. Data was generated from the teachers' (n = 253) written responses to test that was a shortened form of a…
Reducing Sexual Risk Behaviors and Alcohol Use among HIV-Positive Men Who Have Sex with Men: A Randomized Clinical Trial
Velasquez, Mary M.; von Sternberg, Kirk; Johnson, David H.; Green, Charles; Carbonari, Joseph P.; Parsons, Jeffrey T.
This randomized clinical trial (N = 253) evaluated the efficacy of a theory-based intervention designed to reduce both alcohol use and incidence of unprotected sexual behaviors among HIV-positive men who have sex with men with alcohol use disorders. An integrated, manualized intervention, using both individual counseling and peer group…
Gas dynamic lasers. 1964-June, 1980 (citations from the NTIS data base). Report for 1964-June 1980
Energy Technology Data Exchange (ETDEWEB)
Carrigan, B.
The citations cover research on kinetic and energy transfer processes, design, optics, nozzles, and performance of gas and chemical lasers relying on gas dynamic effects for lasing enhancement. Diffusion and flow studies specifically applicable to such lasers are also included. (This updated bibliography contains 253 citations, 6 of which are new entries to the previous edition.)
42 CFR 447.250 - Basis and purpose.
... 42 Public Health 4 2010-10-01 2010-10-01 false Basis and purpose. 447.250 Section 447.250 Public Health CENTERS FOR MEDICARE & MEDICAID SERVICES, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED... requires that payments be consistent with efficiency, economy, and quality of care; (c) Sections 447.253...
A mesoscopic field theory of ionic systems versus a collective variable approach
Energy Technology Data Exchange (ETDEWEB)
Patsahan, Oksana; Mryglod, Ihor [Institute for Condensed Matter Physics of the National Academy of Sciences of Ukraine 1 Svientsitskii Str. 79011 Lviv (Ukraine)
We establish a link between the two functional approaches: a mesoscopic field theory developed recently by Ciach and Stell (2000 J. Mol. Liq. 87 253) for the study of ionic models and an exact statistical field theory based on the method of collective variables. (letter to the editor)
Aiding and Abetting: The Responsibility of Business Leaders under the Rome Statute of the International Criminal Court
Directory of Open Access Journals (Sweden)
Caspar Plomp
Full Text Available While no business leaders have yet been charged before the International Criminal Court (ICC, such future proceedings will typically be conducted with reference to the accessorial mode of liability of aiding and abetting, under Article 25(3(c of the Rome Statute of the ICC. There exist diverse and competing interpretations of Article 25(3(c. This paper aims to advocate the creation of a dominant interpretation of Article 25(3(c and, consequently, to the clarification of the potential responsibility of business leaders who aid or abet crimes under the jurisdiction of the Rome Statute, in two ways. First, it asks whether Article 25(3(c can be interpreted in harmony with the dominant practice on aiding and abetting in international criminal law generally. Second, it presents a case study on the provision of arms by the Russian corporation Rosoboronexport to the Syrian government, which is likely to have committed crimes against humanity since March 2011 and war crimes since mid-2012. The theoretical conclusions are applied to a discussion on the potential criminal responsibility of the Director General of Rosoboronexport for aiding and abetting the commission of international crimes by high-level Syrian officials.
Bank Risk-Taking Abroad : Does Home-Country Regulation and Supervision Matter
Ongena, S.; Popov, A.; Udell, G.F.
This paper provides the first empirical evidence on how home-country regulation and supervision affects bank risk-tailing in hostr-country markets. We analyze lending by 136 banks to 8,253 firms in 1,513 different localities across 13 countries. We find strong evidence that laxer regulatory restrict
Bank Risk-Taking Abroad : Does Home-Country Regulation and Supervision Matter
Ongena, S.; Popov, A.; Udell, G.F.
This paper provides the first empirical evidence on how home-country regulation and supervision affects bank risk-tailing in host-country markets. We analyze lending by 136 banks to 8,253 firms in 1,513 different localities across 13 countries. We find strong evidence that laxer regulatory restricti
Factors Affecting the Job Satisfaction of Latino/a Immigrants in the Midwest
Valdivia, Corinne; Flores, Lisa Y.
This study examined the job satisfaction of 253 Latino/a newcomers in three rural communities in the Midwest. Specifically, the authors explored the effects of ethnic identity, Anglo acculturation, Latino/a acculturation, perceptions of the community (social relations, discrimination/racism, and language pressures), job tenure, work hours, and…
Job Characteristics and College Performance and Attitudes: A Model of Work-School Conflict and Facilitation
Butler, Adam B.
The processes linking job characteristics to school performance and satisfaction in a sample of 253 full-time college students were examined from 2 role theory perspectives, 1 of which emphasized resource scarcity and the other resource expansion. Model tests using structural equation modeling showed that 2 resource-enriching job characteristics,…
... The Problem Risk Factors Prevention Additional Resources How big is the problem? From 2005-2014, there were ... 250-253. U.S. Coast Guard, Department of Homeland Security (US). Recreational ... States Coast Guard data. Injury Prevention 2011;17:156-159.14. Driscoll ...
34 CFR 643.23 - How does the Secretary set the amount of a grant?
... grant on the basis of— (1) 34 CFR 75.232 and 75.233, for new grants; and (2) 34 CFR 75.253, for the...) OFFICE OF POSTSECONDARY EDUCATION, DEPARTMENT OF EDUCATION TALENT SEARCH How Does the Secretary Make a... by the Office of Management and Budget under control number 1840-0549) (Authority: 20 U.S.C. 1070a-11)...
75 FR 78617 - Final Flood Elevation Determinations
... downstream of Martin Hot Spring County. Luther King Boulevard. Approximately 1,300 feet +263 downstream of Martin Luther King Boulevard. Town Creek Approximately 2,300 feet +253 Unincorporated Areas of downstream... Executive Order 12866 of September 30, 1993, Regulatory Planning and Review, 58 FR 51735. Executive...
Latex Dipping Machine PLC Control and Its Programming
Directory of Open Access Journals (Sweden)
Yimin Zhang
Full Text Available Latex dipping machine is based on a latex patent products new-production condom and the development of the machine. The latex dipping agencies combined with production condom mechanism. First it realized a 3-dimensional accurate localization system using stepping motors. SIMATIC S7-200 series programmable controller, motion module EM253 and stepping motor are tied in wedlock to realize allocation of 3-dimension of X axis and Y axis and Z axis. Through the PTO pulse of Siemens S7-200 PLC controller and combined with the use of EM253 module, through the mould precise control programming soak glue and roll edge to achieve the control mold of rotation and swinging the uniform distributed latex. And the system has applied successfully in foreign-funded enterprise of Singapore.
Institute of Scientific and Technical Information of China (English)
黄晓磊; 陈洁
Comparative analysis of antimicrobial and proteolytic activity of lactic acid bacteria isolated from Zlatar cheese
Directory of Open Access Journals (Sweden)
Topisirović Ljubiša
Full Text Available Traditional artisan Zlatar cheese belongs to the group of white, semi hard home-made cheeses, which are produced from no pasteurized cow's milk, without addition of any known bacterial starter culture. In total, 253 Gram-positive and catalase negative lactic acid bacteria (LAB were isolated. Results showed that 70 out of 253 analyzed isolates produced antimicrobial compounds known as bacteriocins. Most isolates from genera Lactococcus and Enterococcus, and isolates belonging to species Lactobacillus plantarum and Lb. brevis, do not synthesize extracellular proteinase. In contrast, isolates from subspecies Lb. paracasei subsp. paracasei showed very good proteolytic activity. It was observed that good proteolytic activity of isolates was not in correlation with their good antimicrobial activity in the most of isolates.
Submillimetric study of nearby galaxies: A tool for new extragalactic molecules
Villicana Pedraza, Ilhuiyolitzin; Guesten, Rolf; Armijos Abendaño, Jairo; Carreto, Francisco; Martin, Sergio; Martin-Pintado, Jesus; Requena-Torres, Miguel; Perez-Beaupuits, Juan Pablo
We present the first submillimetre line survey of extragalactic sources carried out by APEX, the results were presented inside of Villicana-Pedraza phd thesis in 2015. The surveys cover the 0.8 mm atmospheric window toward NGC253, NGC4945 and Arp220. We found HCN, C2H, CN, CS, C34S, HCO+, HNC, CO, N2H+, CH3OH are presents in all the sources, while 13CO,C18O and C17O, HNCO, H2CO, H2CS, SO, NO, SO2 were detected toward NGC253 and NGC4945, 13CN, *CO+, OCS, H2S in Arp220, 13CS, NH2CN, SiO in NGC253, and c-C3H2 in NGC4945 were detected. Column densities and rotation temperatures have been determinate using the Local Thermodinamical Equilibrium(LTE) line profile simulation and fitting in the MADCUBA IJ software. The differences found in the 32S/34S and 18O/17O ratios between the GC and the starburst galaxies NGC 4945 and NGC 253 suggest that the gas is less processed in the latter than in the GC. The high 18O/17O ratios in the galaxies NGC 4945 and NGC 253 suggest also material less processed in the nuclei of these galaxies than in the GC. This is consistent with the claim that 17O is a more representative primary product than 18O in stellar nucleosynthesis (Wilson and Rood 1994); Also, we did a Multitransitions study of H3O+ at 307GHz, 364GHz, 388GHz and 396GHz. From our non-LTE analysis of H3O+ in NGC253 with RADEX we found that the collisional excitation cannot explain the observed intensity of the ortho 396 GHz line. Excitation by radiation from the dust in the Far-IR can roughly explain the observations if the H2 densities are relatively low. From the derived H3O+ column densities we conclude that the chemistry of this molecule is dominated by ionization produce by the starburst in NGC253 (UV radiation from the O stars) and Arp 220 (cosmic rays from the supernovae) and likely from the AGN in NGC4549 (X-rays ); We report, for the first time, the tentative detection of the molecular ion HCNH+ (precursor of HCN and HNC) toward a galaxy, NGC4945, the abundance is much
高架桥薄壁空心高墩施工%Construction Organizational Design for High Hollow Thin-wall Pier of Viaduct Bridge
Institute of Scientific and Technical Information of China (English)
PJ-200 Cantilever formwork ( climbing formwork ) and big steel formwork lifted with tower crane ( turnover formwork construction) have been adopted for the construction of high hollow thin-wall pier of Hewei Bridge at Km:253+353 of Lechang-Guangzhou Expressway, which has achieved good economic benefits.%乐昌至广州高速公路K253+353河尾大桥薄壁空心高墩施工组织设计采用PJ-200悬臂模板(即爬模施工)和塔吊提升大块钢模的方法施工(即翻模施工)相结合的方式,取得了较好的经济效益。
Lifescience Database Archive (English)
Full Text Available 1. 5' end sequence. DK947757 - Show DK947757 Clone id YMU02A01NGRL0016_O11 Library YMU02 Length 253 Definiti...on Adiantum capillus-veneris mRNA. clone: YMU02A01NGRL0016_O11. 5' end sequence. Accession DK947757 Tissue t... database search programs, Nucleic Acids Res. 25:3389-3402. Query= DK947757|Adiantum capillus-veneris mRNA, ...rch programs, Nucleic Acids Res. 25:3389-3402. Query= DK947757|Adiantum capillus-...YMU02A01NGRL0016_O11 253 Adiantum capillus-veneris mRNA. clone: YMU02A01NGRL0016_O1
Nova espécie de Bronia Gray, 1845, do Estado do Tocantins, Brasil (Squamata: Amphisbaenidae
Directory of Open Access Journals (Sweden)
Carolina Castro-Mello
Full Text Available Bronia saxosa, sp. n., localidade tipo UHE Luis Eduardo Magalhães, Estado do Tocantins, difere das demais espécies de Bronia Gray, 1865, principalmente por possuir nasais pequenas separadas pela rostral. A nova espécie possui 4 poros, 253-272 anéis corporais, 17-21 anéis caudais, 18-24/1621 segmentos em um anel no meio do corpo.Bronia saxosa, sp. n. from the state of Tocantins, Brasil, (Hydroelectric Dam Luis Eduardo Magalhães, 09°45'S, 48°21'W, a cerrado area, differs from the remainining species of the genus mainly by having small nasals scutes separated by the rostral. It has (82 specimens 4 preanal pores, 253-272 body annuli, 17-21 tail annuli and 18-24/16-21 segments to a midbody annulus.
An audit on virological efficacy of anti-retroviral therapy in a specialist infectious disease clinic.
LENUS (Irish Health Repository)
Reyad, A
We have assessed the efficacy of anti retroviral therapy (ART) using undetectable viral load (VL) (<50 RNA copies\\/ml) as a marker of virological success, in patients who have Human Immunodeficiency Virus (HIV) attending the Department of Infectious Disease. A cross-sectional review of patients\\' case notes was used to obtain their demographics and treatment details. 79% (253) of the hospital case notes of clinic population was available for analysis, which represents 90% of those receiving ART in the clinic. 166\\/253 of the cohort were receiving treatment at the time of this study and 95% (157\\/166) of these were on treatment for greater than 6 months. The total virological success rate is 93%, which is comparable to other centres and are as good as those from published clinical trials. 56% of those on therapy who have virological failure were Intravenous Drug Users (IVDUs). Case by case investigation for those with treatment failure is warranted.
The Reverse Transformation Behavior of TiNi Shape Memory Alloy Wires Prestrained at Different Temperatures
Institute of Scientific and Technical Information of China (English)
HuaiLimin; CuiLishan; ZhangLaibin; ZhengYanjun
The reverse transformation behavior of TiNi alloy wires prestrained at different temperatures is studied in this paper. Experimental results show that prestrain at different temperatures obviously affects the reverse transformation behavior of the TiNi alloy wire. A single peak appears on the DSC curves of wires prestrained at 253-313K (in the martensite state). However deformed at 333K, three consecutive peaks appear on the DSC curves of wires with a smaller prestrain and a single peak appears on the DSC curves of the wires with a larger prestrain. The recovery strain ratio of the wires prestrained at 253-313K are very similar. However, the ratio of the wire predeformed at 333K is obviously smaller than that of the wire prestrained in the martensite state.
End product inhibition of hepatic 25-hydroxyvitamin D production in the rat: specificity and kinetics
International Nuclear Information System (INIS)
The role of vitamin D metabolites in the regulation of hepatic 25-hydroxyvitamin D production was investigated by examining the effects of 25-hydroxyvitamin D, 1,25-dihydroxyvitamin D, and 24,25-dihydroxyvitamin D on the synthesis of [25-3H]hydroxyvitamin D by rachitic rat liver homogenates. Production of [25-3H]hydroxyvitamin D was inhibited by 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D, but not by 24,25-dihydroxyvitamin D. 25-Hydroxyvitamin D increased the Km of the vitamin D-25-hydroxylase enzyme(s), while 1,25-dihydroxyvitamin D decreased the Vmax with a Ki of 88.7 ng/ml. Inhibition of hepatic 25-hydroxyvitamin D production by 25-hydroxyvitamin D and 1,25-dihydroxyvitamin D may be another control mechanism to regulate circulating vitamin D levels
A study on the effects of some laboratory-derived genetic mutations on biofilm formation by Listeria monocytogenes
Digital Repository Service at National Institute of Oceanography (India)
Kumar, S.; Parvathi, A.; George, J.; Krohne, G.; Karunasagar, Indrani; Karunasagar, Iddya
=UTF-8 0 Author version: World J. Microbiol. Biotechnol.: 25(3); 2009; 527-531 A study on the effects of some laboratory derived genetic mutations on biofilm formation by Listeria monocytogenes Sanath Kumar 1 . Ammini Parvathi 2 . Jeffy... found to have no role, others had varying effects from moderate to severe, on attachment and biofilm formation by L. monocytogenes. Materials and methods Bacterial strains and media Two wild type (WT) strains EGDe (BAA-679, serotype 1/2a) and its...
On the airbursts of large meteoroids in the Earth's atmosphere
Foschini, L
On January 19, 1993, a very bright bolide (peak magnitude -23) crossed Northern Italy, ending with an explosion approximately over the town of Lugo (Emilia Romagna, Italy). The explosion (14 kton) generated shock waves that were recorded by six local seismic stations. A reanalysis of collected data allows us to hypothesize that the meteoroid was a porous carbonaceous chondrite somehow like the asteroid 253 Mathilde.
Constraints on the Existence of Strange Quark Stars
Balberg, Shmuel
Creation of strange quark stars through strong interaction deconfinement is studied based on modern estimates of hyperon formation in neutron stars. The hyperon abundance is shown to be large enough so that if strange quark matter (SQM) is the true ground state of matter, the deconfinement density should be at most 2.5-3 times the nuclear saturation density. If so, deconfinement occurs in neutron stars at birth, and all neutron stars must be strange quark stars. Alternatively, sould observati...
The relationship between the rate of melatonin excretion and sleep consolidation for locomotive engineers in natural sleep settings
Roach, Gregory D.; Reid, Kathryn J.; Ferguson, Sally; Dawson, Drew
Background: The aim of the study was to examine the role that melatonin production plays in the regulation of sleep consolidation in a population of shiftworkers working and sleeping in their natural environments.Methods: 253 locomotive engineers (249 male, 4 female, mean age = 39.7 years) participated in the study for a 2-week period whilst working their normal roster patterns. Participants recorded details for all sleep periods in a sleep diary and collected urine samples during each day's ...
Iron content and reducing capacity of granites and bentonite
International Nuclear Information System (INIS)
The iron contents in various granites and in bentonite have been determined. For granites, the content is usually in the range 1-9% (weight) and 2.5-3% for bentonite. Most of the iron is divalent in the granites (70-90%); in bentonite the divalent fraction is 25-50%. A large part of the divalent iron in the granites appears to be accessible for the reduction of dissolved oxygen in an aqueous system. (author)
Defining the role of common variation in the genomic and biological architecture of adult human height
DEFF Research Database (Denmark)
Wood, Andrew R.; Esko, Tonu; Yang, Jian;
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing different numbers of variants in independent studies, we show that the most strongly associated similar to 2,0......TOR, osteoglycin and binding of hyaluronic acid. Our results indicate a genetic architecture for human height that is characterized by a very large but finite number (thousands) of causal variants....
The impact of site of graduate medical education training and other factors on physician employee retention.
Petrou, Steven P; Lee, Marian D; Griffis, Julie; Rawal, Bhupendra; Robinson, Nell; Murray, Peter M
This study sought to determine if the site of graduate medical training or other factors impact the length of institutional employment. Physician hires for the home institution were catalogued from January 1, 1996, through December 31, 2006. In analyzing the 253 physician hires, we found no statistically significant advantage in employee retention associated with hiring "one's own" or with U.S. medical school graduates.
Mapping ceramics research and its evolution
Deville, Sylvain; Stevenson, Adam J.
We show here how a simple data mining of bibliographic records can be used to follow and help understand the evolution of a research domain, at a level that cannot be captured by reading individual papers in a field of this size. We illustrate the approach by investigating 43 years of research on ceramic materials, covered by 253k bibliographic records. The patterns of keywords used reveal the trends and the evolution of research ideas and priorities within the field. Simple, interactive tool...
Paternal inheritance of mitochondrial DNA in the sheep (Ovine aries)
Institute of Scientific and Technical Information of China (English)
Paternal inheritance of mitochondria DNA in sheep was discovered by examination of 152 sheep from 38 hybrid families for mtDNA D-loop polymorphisms using PCR-RFLP, amplification of repeated sequence somain, and PCR-SSCP of the D-loop 5′ end region of a 253 bp fragment. Our findings have provided the first evidence of paternal inheritance of mtDNA in sheep and possible mechanisms of paternal inheritance were discussed.
Relationships among parental monitoring and sensation seeking on the development of substance use disorder among college students
Kaynak, Övgü; Meyers, Kathleen; Caldeira, Kimberly M.; Vincent, Kathryn B.; Winters, Ken C.; Arria, Amelia M.
Substance use disorder is a serious health problem that tends to manifest in late adolescence. Attempting to influence targetable risk and protective factors holds promise for prevention and treatment. Survey data from 1,253 college students (48.5% male, 26.9% non-White) were used to investigate the independent and combined effects of two prominent factors, sensation seeking and parental monitoring, on the probability of alcohol and/or cannabis dependence during the first year of college. In ...
Institute of Scientific and Technical Information of China (English)
920740 Diagnosis value of suspect epilepsyby means of 24 hrs ambulatory EEG.YU Hongjun(喻红军), WU Xun(吴逊). ChinaRailway Building Hosp, Beijing,100043. ChinJ Neurol & Psychiat 1992; 25(3): 133-135. One hundred and six cases of suspect epilepsyrandomly observed by means of 24 hrs taperecording of AEEG were given in this paper.
Inhibition of inducible heat shock protein-70 (hsp72 enhances bortezomib-induced cell death in human bladder cancer cells.
Directory of Open Access Journals (Sweden)
Wei Qi
Full Text Available The proteasome inhibitor bortezomib (Velcade is a promising new agent for bladder cancer therapy, but inducible cytoprotective mechanisms may limit its potential efficacy. We used whole genome mRNA expression profiling to study the effects of bortezomib on stress-induced gene expression in a panel of human bladder cancer cell lines. Bortezomib induced strong upregulation of the inducible HSP70 isoforms HSPA1A and HSPA1B isoforms of Hsp72 in 253J B-V and SW780 (HSPA1A(high cells, but only induced the HSPA1B isoform in UM-UC10 and UM-UC13 (HSPA1A(low cells. Bortezomib stimulated the binding of heat shock factor-1 (HSF1 to the HSPA1A promoter in 253JB-V but not in UM-UC13 cells. Methylation-specific PCR revealed that the HSPA1A promoter was methylated in the HSPA1A(low cell lines (UM-UC10 and UM-UC13, and exposure to the chromatin demethylating agent 5-aza-2'-deoxycytidine restored HSPA1A expression. Overexpression of Hsp72 promoted bortezomib resistance in the UM-UC10 and UM-UC13 cells, whereas transient knockdown of HSPA1B further sensitized these cells to bortezomib, and exposure to the chemical HSF1 inhibitor KNK-437 promoted bortezomib sensitivity in the 253J B-V cells. Finally, shRNA-mediated stable knockdown of Hsp72 in 253J B-V promoted sensitivity to bortezomib in vitro and in tumor xenografts in vivo. Together, our results provide proof-of-concept for using Hsp72 inhibitors to promote bortezomib sensitivity in bladder cancers and suggest that selective targeting of HSPA1B could produce synthetic lethality in tumors that display HSPA1A promoter methylation.
International Nuclear Information System (INIS)
We present a photometric survey of the optical counterparts of ultraluminous X-ray sources (ULXs) observed with the Hubble Space Telescope (HST) in nearby (∼V of ∼ –4 to –9, enabling us to rule out O-type companions in 4 cases. The refined positions of two ULXs place them in the nucleus of their host galaxy. They are removed from our sample. Of the 22 remaining ULXs, 13 have one possible optical counterpart, while multiple are visible within the error regions of other ULXs. By calculating the number of chance coincidences, we estimate that 13 ± 5 are the true counterparts. We attempt to constrain the nature of the companions by fitting the spectral energy distribution and MV to obtain candidate spectral types. We can rule out O-type companions in 20 cases, while we find that one ULX (NGC 253 ULX2) excludes all OB-type companions. Fitting with X-ray irradiated models provides constraints on the donor star mass and radius. For seven ULXs, we are able to impose inclination-dependent upper and/or lower limits on the black holes' mass, if the extinction to the assumed companion star is not larger than the Galactic column. These are NGC 55 ULX1, NGC 253 ULX1, NGC 253 ULX2, NGC 253 XMM6, Ho IX X-1, IC342 X-1, and NGC 5204 X-1. This suggests that 10 ULXs do not have O companions, while none of the 18 fitted rule out B-type companions.
Energy Technology Data Exchange (ETDEWEB)
Gladstone, Jeanette C.; Heinke, Craig O.; Cartwright, Taylor F. [Department of Physics, University of Alberta, 11322-89 Avenue, Edmonton, Alberta T6G 2G7 (Canada); Copperwheat, Chris [Department of Physics, Liverpool John Moores University, Wirral CH41 1LD (United Kingdom); Roberts, Timothy P. [Department of Physics, University of Durham, South Road, Durham DH1 3LE (United Kingdom); Levan, Andrew J. [Department of Physics, University of Warwick, Coventry CV4 7VL (United Kingdom); Goad, Mike R., E-mail: email@example.com [Department of Physics and Astronomy, University of Leicester, University Road, Leicester LE1 7AL (United Kingdom)
We present a photometric survey of the optical counterparts of ultraluminous X-ray sources (ULXs) observed with the Hubble Space Telescope (HST) in nearby ({approx}<5 Mpc) galaxies. Of the 33 ULXs with HST and Chandra data, 9 have no visible counterpart, placing limits on their M{sub V} of {approx} -4 to -9, enabling us to rule out O-type companions in 4 cases. The refined positions of two ULXs place them in the nucleus of their host galaxy. They are removed from our sample. Of the 22 remaining ULXs, 13 have one possible optical counterpart, while multiple are visible within the error regions of other ULXs. By calculating the number of chance coincidences, we estimate that 13 {+-} 5 are the true counterparts. We attempt to constrain the nature of the companions by fitting the spectral energy distribution and M{sub V} to obtain candidate spectral types. We can rule out O-type companions in 20 cases, while we find that one ULX (NGC 253 ULX2) excludes all OB-type companions. Fitting with X-ray irradiated models provides constraints on the donor star mass and radius. For seven ULXs, we are able to impose inclination-dependent upper and/or lower limits on the black holes' mass, if the extinction to the assumed companion star is not larger than the Galactic column. These are NGC 55 ULX1, NGC 253 ULX1, NGC 253 ULX2, NGC 253 XMM6, Ho IX X-1, IC342 X-1, and NGC 5204 X-1. This suggests that 10 ULXs do not have O companions, while none of the 18 fitted rule out B-type companions.
SXDF-ALMA 1.5 arcmin2 Deep Survey: A Compact Dusty Star-forming Galaxy at z = 2.5
Tadaki, Ken-ichi; Kohno, Kotaro; Kodama, Tadayuki; Ikarashi, Soh; Aretxaga, Itziar; Berta, Stefano; Caputi, Karina I.; Dunlop, James S.; Hatsukade, Bunyo; Hayashi, Masao; Hughes, David H.; Ivison, Rob; Izumi, Takuma; Koyama, Yusei; Lutz, Dieter; Makiya, Ryu; Matsuda, Yuichi; Nakanishi, Kouichiro; Rujopakarn, Wiphu; Tamura, Yoichi; Umehata, Hideki; Wang, Wei-Hao; Wilson, Grant W.; Wuyts, Stijn; Yamaguchi, Yuki; Yun, Min S.
We present the first results from the SXDF-Atacama Large Millimeter/submillimeter Array (ALMA) 1.5 arcmin2 deep survey at 1.1 mm using ALMA. The map reaches a 1σ depth of 55 μJy/beam and covers 12 Hα-selected star-forming galaxies (SFGs) at z = 2.19 or z = 2.53. We have detected continuum emission f
Ar-Ar and U-Pb geochronology of Late Paleozoic basalts in western Guangxi and its constraints on the eruption age of Emeishan basalt magmatism
Institute of Scientific and Technical Information of China (English)
FAN Weiming; WANG Yuejun; PENG Touping; MIAO Laicheng; GUO Feng
The Late Paleozoic layered or stratoid-layered basalts in western Guangxi have similar elemental and isotopic compositions to Emeishan high-Ti basalts. Whole-rock 40Ar/39Ar and SHRIMP zircon U-Pb dating were carried out for the representative basalt samples in three typical profiles in the area. Three basalts from the upper segment of Yangxu profile and lower segment of Yufeng and Min'an profiles yield the 40Ar/39Ar plateau ages of 253.6±0.4 Ma (20BS-71),255.4±0.4 Ma (20BS-99) and 256.2±0.8 Ma (20BS-119), respectively. Twenty-three analyses on 23 zircons of the basalt from the upper segment of Yangxu profile give a weighted mean 206pb/238U age of 253.7±6.1 Ma with an MSWD = 2.8.These new and published geochronological data for Emeishan large igneous province (LIP) indicate that the Emeishan LIP was initiated at ~260 Ma, voluminously erupted between 253 and 256 Ma, and possibly ended at ~251-253Ma' The age (251-260 Ma) is generally consistent with that of the associated environmental deterioration and mass extinction events at the end-Guadalupian and Permo-Triassic boundary. These precise geochronological data provide important constraints on the dominantly eruptive time of the Emeishan LIP and understanding of the distribution of Emeishan high-Ti basalts and its mantle plume dynamics.
42 CFR 84.256 - Quality control requirements.
... 42 Public Health 1 2010-10-01 2010-10-01 false Quality control requirements. 84.256 Section 84.256... § 84.256 Quality control requirements. (a) In addition to the construction and performance requirements specified in §§ 84.251, 84.252, 84.253, 84.254, and 84.255, the quality control requirements in...
Institute of Scientific and Technical Information of China (English)
Housing provident funds are plagued by non-use and embezzlement Embezzlement on a grand scale is sending shock waves through the Chinese provident fund industry. During 2005, a host of incidents were made public, with several serious cases involving funds of over 100 million yuan ($12.5 million). Recently, Liu Xiangyang, Director of Hengyang Housing Provident Fund Center in central China's Hunan Province, was charged with the embezzlement of 253 mil
Prescription pattern of analgesics in orthopedics outpatient department at a tertiary care hospital
Directory of Open Access Journals (Sweden)
R. Bhaskar
Conclusions: The results of the present study show frequent use of selective COX-2 inhibitors, although non-selective NSAIDs topped the list of various selective NSAIDs, non-selective NSAIDs, and opioid analgesics. This suggests that gastrointestinal safety was an important concern while prescribing these drugs. Many FDCs were found to be irrational. [Int J Basic Clin Pharmacol 2015; 4(2.000: 250-253
Dynamic Evolution of Toll-Like Receptor Multigene Families in Echinoderms
Buckley, Katherine M; Rast, Jonathan P.
The genome sequence of the purple sea urchin, Strongylocentrotus purpuratus, a large and long-lived invertebrate, provides a new perspective on animal immunity. Analysis of this genome uncovered a highly complex immune system in which the gene families that encode homologs of the pattern recognition receptors that form the core of vertebrate innate immunity are encoded in large multigene families. The sea urchin genome contains 253 Toll-like receptor (TLR) sequences, more than 200 Nod-like re...
Comparison of different measures of urinary protein excretion for prediction of renal events
DEFF Research Database (Denmark)
Lambers Heerspink, Hiddo J; Gansevoort, Ron T; Brenner, Barry M;
the log-transformed measures were 3.16 (2.60 to 3.86) for UAE, 3.02 (2.53 to 3.62) for UPE, 3.23 (2.67 to 3.91) for UAC, and 4.36 (3.50 to 5.45) for ACR. The area under the ROC curve was significantly higher for ACR compared with the other measures. In conclusion, measurement of the albumin...
Identification and characterization of glucoamylase from the fungus, Thermomyces lanuginosus
DEFF Research Database (Denmark)
Thorsen, Thor Seneca; Johnsen, Anders; Josefsen, K.;
The glucoamylase from the thermophilic fungus Thermomyces lanuginosus has a molecular weight of 66 kDa and was characterized with isoelectric point, pH and temperature optimum of 3.8-4.0, 5.0 and 70 °C, respectively. In addition, the activation energy is 60.4 kJ/mol, Km is 3.5 mM and kcat is 25.3...
Detection efficiency evaluation for a large area neutron sensitive microchannel plate detector
Wang, Yiming; Yang, Yigang; Liu, Ren
In this paper, the detection efficiency of a large area neutron sensitive microchannel plate detector has been evaluated. A 6LiF/ZnS detector was employed as the benchmark detector, the TOF spectra of these two detectors were simultaneously measured and the energy spectra were then deduced to calculate the detection efficiency curve of the nMCP detector. Tests show the detection email@example.com meV thermal neutron is 34% for this nMCP detector.
Prognostic implications of the IDH1 synonymous SNP rs11554137 in pediatric and adult AML: a report from the Children's Oncology Group and SWOG
Ho, Phoenix A.; Kopecky, Kenneth J.; Alonzo, Todd A.; Gerbing, Robert B.; Miller, Kristen L.; Kuhn, Julia; Zeng, Rong; Ries, Rhonda E.; Raimondi, Susana C; Hirsch, Betsy A.; Oehler, Vivian; Hurwitz, Craig A.; Franklin, Janet L.; Gamis, Alan S.; Petersdorf, Stephen H.
IDH1 SNP rs11554137 was recently reported in association with poor prognosis in normal karyotype adult acute myeloid leukemia (AML). We aimed to determine the prevalence, clinical associations, and prognostic significance of SNP rs11554137 in unselected pediatric and adult AML patients. Diagnostic marrow specimens from 527 AML patients treated on the pediatric trial Children's Oncology Group-AAML03P1 (N = 253) or adult SWOG trials (N = 274) were analyzed for the presence of the SNP. SNP rs115...
Perceived harmfulness predicts nonmedical use of prescription drugs among college students: Interactions with sensation-seeking
Arria, Amelia M.; Caldeira, Kimberly M.; Vincent, Kathryn B.; O'Grady, Kevin E.; Wish, Eric D.
This study describes the level of perceived harmfulness of nonmedical prescription stimulant and analgesic use in a sample of college students, and examines the prospective relationship between perceived harmfulness and subsequent nonmedical use. In addition, we explore whether the association between perceived harmfulness and nonmedical use varies by level of sensation-seeking. Personal interviews, including questions on sensation-seeking and drug use, were conducted with 1,253 first-year co...
WISP-1 overexpression upregulates cell proliferation in human salivary gland carcinomas via regulating MMP-2 expression
Li, Fu-Jun; Wang, Xin-Juan; Zhou, Xiao-Li
Background WISP-1 is a member of the CCN family of growth factors and has been reported to play an important role in tumorigenesis by triggering downstream events via integrin signaling. However, little is known about the role of WISP-1 in proliferation of salivary gland carcinoma (SGC) cells. Methods In this study, we investigated the WISP-1 expression in SGC tissues via immunohistochemical staining, Western blotting assay, and real-time quantitative polymerase chain reaction method, and then evaluated the regulatory role of WISP-1 in the growth of SGC A-253 cells. In addition, the role of MMP-2 in the WISP-1-mediated growth regulation was also investigated. Results It was demonstrated that the WISP-1 expression was upregulated at both mRNA and protein levels in 15 of 21 SGC tumor tissues, compared to the non-tumor tissues (five of 21), associated with the lymph node dissection and bone invasion. The in vitro CCK-8 assay and colony-forming assay demonstrated that the exogenous WISP-1 treatment or the WISP-1 overexpression promoted the growth of A-253 cells. In addition, we confirmed that the WISP-1 overexpression upregulated the MMP-2 expression in A-253 cells with the gain-of-function and loss-of-function strategies, and that the MMP-2 knockdown attenuated the WISP-1-mediated growth promotion of A-253 cells. Conclusion We found that WISP-1 was overexpressed in the human SGCs, and the WISP-1 overexpression promoted the salivary gland cell proliferation via upregulating MMP-2 expression. Our study recognized the oncogenic role of WISP-1 in human SGCs, which could serve as a potential target for anticancer therapy. PMID:27799801
Context for the Recent Massive Petermann Glacier Calving Event
DEFF Research Database (Denmark)
Falkner, Kelly K.; Melling, Humfrey; Münchow, Andreas M.;
On 4 August 2010, about one fifth of the floating ice tongue of Petermann Glacier (also known as "Petermann Gletscher") in northwestern Greenland calved (Figure 1). The resulting "ice island" had an area approximately 4 times that of Manhattan Island (about 253±17 square kilometers). The ice isla...... as part of the glacier's natural variability? Understanding the known historical context of this event allows scientists and the public to judge its significance....
Lifescience Database Archive (English)
Full Text Available 112111 Link to Original y[*] w[*] P{GawB}NP0253 / FM7c 12F4 ; -; 12F5 Link to DGRC Genome Viewer: 112111...cells all tr, strong in terminal cells sg, gut - - - - d1 - - - Show 112111 DGRC Number 112111...wer Link to DGRC Genome Viewer: 112111 Related Genes CG14408 rut Original Number 253 Chr. 1 Comments FlyBase
Body composition, somatotype and risk of premenopausal breast cancer: a case-control study in Uruguay
Ronco AL; De Stefani E; Deneo-Pellegrini H
In order to analyze detailed anthropometric characterisation for risk of breast cancer (BC) in premenopausal Uruguayan women, a case-control study was carried out at the Pereira Rossell Women's Hospital, Montevideo, where 253 incident BC cases and 497 frequency-matched healthy controls were interviewed on menstrual and reproductive story, and a series of body measurements were performed to calculate body composition and somatotype. Odds ratio (OR's) coefficients were taken as estimates of rel...
Institute of Scientific and Technical Information of China (English)
920737 Acute herpes simplex encephalitispatients treated with acyclovia-a reportof five cases.HOU Xide(侯熙德), et al. DeptNeurol, 1st Affil Hosp, Nanjing Med Coll, 210029.Chin J Neurol & Psychiat 1992; 25(3): 143-145. Five cases of acute herpes simplex encephalitiswere verified by specific IgG antibodies in cere-brospinal fluid and serum among 31 cases with
Lifescience Database Archive (English)
Full Text Available D07795 Drug Detomidine (INN) C12H14N2 186.1157 186.253 D07795.gif Analgesic [veteri...nary]; Hypnotic, sedative [veterinary] alpha2-adrenergic receptor agonist [HSA:150 151 152] [KO:K04138 K0413...9 K04140] hsa04080(150+151+152) Neuroactive ligand-receptor interaction Target-based classification of drugs... [BR:br08310] G Protein-coupled receptors Rhodopsin family Adrenaline alpha2-adre
Barriers to Mental Health Service Use among Hematopoietic Stem Cell Transplant Survivors
Mosher, Catherine E.; DuHamel, Katherine N.; Rini, Christine M.; Li, Yuelin; Isola, Luis; Labay, Larissa; Rowley, Scott; Papadopoulos, Esperanza; Moskowitz, Craig; Scigliano, Eileen; Grosskreutz, Celia; Redd, William H.
Summary This study examined barriers to mental health service use and their demographic, medical, and psychosocial correlates among hematopoietic stem cell transplant (HSCT) survivors. A sample of 253 HSCT survivors who were 1- to 3-years post-transplant completed measures of demographic, physical, psychological, and social characteristics as well as a newly modified measure of barriers to mental health service use. Only 50% of distressed HSCT survivors had received mental health services. An...
HIV/AIDS相关性慢性腹泻患者感染空肠弯曲菌的临床分析%Infections of Campylobacter Jejuni among Patients with HIV/AIDS-related Chronic Diarrhea
Institute of Scientific and Technical Information of China (English)
华文浩; 王慧珠; 赵辉; 李敏; 张燕; 田敬华; 王玉光
Objective To investigate the Campylobacter jejuni infection status of HIV/AIDS patients with chronic diarrhea in Beijing, Henan, and Xinjiang.Methods Micro - aerobic cultivation of stool specimens were carried out in 253 cases of HIV/AIDS patients with chronic diarrhea in Beijing, Henan, and Xinjiang.The colonies were identified according to morphology, Gram staining, and results frombiochemical reactions.Results Two strains of Campylobacter jejuni were identified from the 253 cases of HIV/AIDS - related chronic diarrhea ( infection rate: 0.8% ).Conclusion It is important that monitoring for Campylobacter jejuni be carried out in high risk patients for prevention and control of the infection of the bacteria.%目的 了解北京、河南、新疆三地HIV/AIDS相关性慢性腹泻患者空肠弯曲菌的感染状况.方法 对北京、河南、新疆三地253例HIV/AIDS慢性腹泻患者的粪便标本进行微需氧培养,根据菌落的形态、菌体的革兰染色及生化反应进行鉴定.结果 从253例HIV/AIDS相关性慢性腹泻患者的粪便中共检出2株空肠弯曲菌,感染率为0.8%.结论 加强空肠弯曲菌的监测是预防和控制空肠弯曲菌病的重要手段.
Domain Modeling: NP_945341.2 [SAHG[Archive
Lifescience Database Archive (English)
Full Text Available NP_945341.2 chr7 Crystal structure of uncharacterized metallo protein from Vibrio c...holerae with beta-lactamase like fold p3bv6a_ chr7/NP_945341.2/NP_945341.2_holo_80-392.pdb swppa 132H,185H,187H,189D,190H,253H,267W,284D,343H _FE 0 ...
The Effect of Perceived Abusive Management of Workers to Their Performance and the Role of Emotional Intelligence on This Effect
AKIN, Mahmut; ÖZDEVECİOĞLU, Mahmut; Karaca, Mustafa; Banu İŞTAHLI
In this research it is evaluated the effect of perceived abusive management of workers to their performance and the role of emotional intelligence on this effect. Research is realized with 253 civil servants in Kırşehir. Workers performance is handled two dimensional. One of them is task performance and the other one is contextual performance. According to the results, emotional intelligence is diminished or eliminated the effects of abusive management on workers performance. Additionally; em...
Paternal and Maternal Influences on Problem Behaviors Among Homeless and Runaway Youth
Stein, Judith A.; Milburn, Norweeta G.; Zane, Jazmin I.; Rotheram-Borus, Mary-Jane
Using an Attachment Theory conceptual framework, associations were investigated among positive paternal and maternal relationships, and recent problem behaviors among 501 currently homeless and runaway adolescents (253 males, 248 females). Homeless and runaway youth commonly exhibit problem behaviors such as substance use, various forms of delinquency and risky sex behaviors, and report more emotional distress than typical adolescents. Furthermore, attachments to their families are often stra...
Growth Pattern of Atherosclerotic Calcifications
DEFF Research Database (Denmark)
Larsen, Lene Lillemark; Ganz, Melanie; Dam, Erik;
of the calcifications are matched longitudinally using thin plate spline registration and area overlap calculations. The growth of the calcifications is measured by the distribution of the geometry statistics of the calcifications. The method was evaluated on 135 subjects with a total number of 611 calcifications. Our...... results show, for instance longitudinal growth of calcifications with a mean of 2.53 mm ($\\pm$ 1.95) in the blood flow direction and correlations with pathologically related biomarkers....
Institute of Scientific and Technical Information of China (English)
2008277 Relationship between pulse wave velocity and the NYHA classification of coronary insufficiency.SUN Weiping(孙卫平),et al.Dept Cardiol,Tongji Hosp Tongji Univ,Shanghai 200065.Chin J Intern Med 2008;47(5):382-384.Objective To investigate the relationship between brachial-ankle pulse wave velocity(baPWV)and different stage of cardiac dysfunction.Methods 253 consecutive patients with coronary atherosclerotic heart disease
HERMES: a personal-computer program for calculation of the Fermi-Gas Model parameters of nuclear level density
International Nuclear Information System (INIS)
A computer program, HERMES, that provides the quantities usually needed in nuclear level density calculations, has been developed. The applied model is the standard Fermi Gas Model (FGM) in which pairing correlations and shell effects are opportunely taken into account. The effects of additional nuclear structure properties together with their inclusion into the computer program are also considered. Using HERMES, a level density parameter systematics has been constructed for mass range 41 ≤ A ≤ 253. (author)
澤村, 大地; 加藤, 千里; 松崎, 真弓; 柳瀬, 和也; 谷口, 陽子; 中井, 泉
Glass products, such as glass beads excavated in Japan from Yayoi to Kofun period sites, were all produced abroad and brought to Japan via unknown ports. This paper reports on the results of non-invasive chemical analysis using a portable XRF on 253 glass beads excavated from various archaeological sites in the Kanto region. The base glasses were classified into three types: i.e., potash glass, soda lime glass, high alumina soda lime glass, which showed similar characteristics to those excava...
New 1kVA mini UPS YUMIC-SC10; Shingata 1kVA mini UPS YUMIC-SC10
Energy Technology Data Exchange (ETDEWEB)
The long life battery (type RE) of about two times is carried in 2.5-3 of before, and it is standard as for the interface with the computer the replacement life interface signal corresponding to the UPS monitor ring function of NetWare of the network OS and WindowsNT. It can cope with a high function UPS monitor ring and schedule operation by adding an optional interface board to the expansion slot more. (NEDO)
Short stature--the role of intelligence in psychosocial adjustment.
Gilmour, J.; Skuse, D
Short children are often described as having psychosocial problems. These reports may be inaccurate as former studies have relied largely on parental report. Psychosocial functioning of short children was assessed with the aim of using them and their peers as informants. Twenty two short (mean (SD) height -2.53 (0.28) SD score) prepubertal children aged between 6 and 11 years were recruited from growth clinics. Comparison children were recruited from each case child's class at school. Cogniti...
Lynn Pan; Herman C. Kemp; David Stuart-Fox; Colin Nicholas; Cornelia M.J. van der Sluys; Paul van Beckum; Remco Raben; Helena A. van Bemmel; John N. MIKSIC; David T. Hill; H.M.J. Maier; John Guy; Ruth Barnes; Rens Heringa; Gavin W. Jones
- Matthew Amster, Jérôme Rousseau, Kayan religion; Ritual life and religious reform in Central Borneo. Leiden: KITLV Press, 1998, 352 pp. [VKI 180.] - Atsushi Ota, Johan Talens, Een feodale samenleving in koloniaal vaarwater; Staatsvorming, koloniale expansie en economische onderontwikkeling in Banten, West-Java, 1600-1750. Hilversum: Verloren, 1999, 253 pp. - Wanda Avé, Johannes Salilah, Traditional medicine among the Ngaju Dayak in Central Kalimantan; The 1935 writings of a former Ngaju Day...
Towards a national system of teaching qualifications in higher education in The Netherlands
Keulen, H. van; van Alst, J.; de Jong, R; Halma, A.
2005 6th Conference of the International Consortium for Educational Development Enhancing Academic Development Practice: International Perspectives 1. Contact Name: Hanno van Keulen 2. Title: Dr 3. Institution(s): Utrecht University 4. Department: IVLOS Institute of Education 5. Address for correspondence: PO Box 80127 6. Country: The Netherlands 7. Postcode/Zipcode: 3508 TC Utrecht 8. Telephone: +31 30 253 1718 (office) / +31 6 5213 8991 (GSM) 9. Email: 10. Title and ...
Quantitative dissection of the binding contributions of ligand lysines of the receptor-associated protein (RAP) to the low density lipoprotein receptor-related protein (LRP1).
Dolmer, Klavs; Campos, Andres; Gettins, Peter G W
Although lysines are known to be critical for ligand binding to LDL receptor family receptors, relatively small reductions in affinity have been found when such lysines have been mutated. To resolve this paradox, we have examined the specific binding contributions of four lysines, Lys-253, Lys-256, Lys-270, and Lys-289, in the third domain (D3) of receptor-associated protein (RAP), by eliminating all other lysine residues. Using D3 variants containing lysine subsets, we examined binding to the high affinity fragment CR56 from LRP1. With this simplification, we found that elimination of the lysine pairs Lys-253/Lys-256 and Lys-270/Lys-289 resulted in increases in Kd of 1240- and 100,000-fold, respectively. Each pair contributed additively to overall affinity, with 61% from Lys-270/Lys-289 and 39% from Lys-253/Lys-256. Furthermore, the Lys-270/Lys-289 pair alone could bind different single CR domains with similar affinity. Within the pairs, binding contributions of Lys-270 ≫ Lys-256 > Lys-253 ∼ Lys-289 were deduced. Importantly, however, Lys-289 could significantly compensate for the loss of Lys-270, thus explaining how previous studies have underestimated the importance of Lys-270. Calorimetry showed that favorable enthalpy, from Lys-256 and Lys-270, overwhelmingly drives binding, offset by unfavorable entropy. Our findings support a mode of ligand binding in which a proximal pair of lysines engages the negatively charged pocket of a CR domain, with two such pairs of interactions (requiring two CR domains), appropriately separated, being alone sufficient to provide the low nanomolar affinity found for most protein ligands of LDL receptor family members.
Dicty_cDB: Contig-U08389-1 [Dicty_cDB
Lifescience Database Archive (English)
Full Text Available tyostelium discoideum cDNA clone:ddv15e03, 3' ... 36 0.23 3 ( EF119975 ) HIV-1 isolate F361 from Argentina v...1 isolate CFARC560 from Argentina vpu protein... 44 1.1 1 >( AU272390 ) Dictyoste...5C8 in l... 44 1.1 1 ( AL772396 ) Zebrafish DNA sequence from clone CH211-253F14. 44 1.1 1 ( DQ767700 ) HIV-
76 FR 38691 - Certain Pipe and Tube From Brazil, India, Korea, Mexico, Taiwan, Thailand, and Turkey
... carbon steel pipe 701-TA-253 51 FR 7984 and tube/Turkey. 3/11/86 Welded carbon steel pipe 731-TA-252 51.../15/86 Welded carbon steel pipe 731-TA-273 51 FR 17784 and tube/Turkey. 3/27/89 Light-walled... imports of welded carbon steel pipe and tube from Turkey (65 FR 50960) and the antidumping duty orders...
友近,建一; 船橋,達天; 丸山, 隆司; 寺坂,薫; 金政,泰弘
A rapid nonstaining method for the determination of the Gram reaction was applied to clinical isolates. In this study, 253 clinical isolates were tested by both the KOH method and Gram staining method. Both methods discriminated 110 of Gram-positive bacteria and Yeast-form fungus, and 143 of Gram-negative bacteria. These results confirmed the application of KOH method to clinical isolates.
Acquisition of Resistance to Extended-Spectrum Cephalosporins by Salmonella enterica subsp. enterica Serovar Newport and Escherichia coli in the Turkey Poult Intestinal Tract
Poppe, C; Martin, L. C.; Gyles, C. L.; Reid-Smith, R.; Boerlin, P.; McEwen, S A; Prescott, J F; Forward, K R
Salmonella enterica subsp. enterica serovar Newport resistant to the extended-spectrum cephalosporins (ESCs) and other antimicrobials causes septicemic salmonellosis in humans and animals and is increasingly isolated from humans, animals, foods, and environmental sources. Mechanisms whereby serovar Newport bacteria become resistant to ESCs and other classes of antimicrobials while inhabiting the intestinal tract are not well understood. The present study shows that 25.3% of serovar Newport st...
The relationship between emotional intelligence and academic adaptation among gifted and non-gifted student
Sabah Hasan Al-Onizat
The purpose of This article was to identifying the relationship between the Emotional Intelligences and Academic adaptation differences between gifted and non-gifted students. To achieve that, sample consists of (684), (253) students from King Second Abdullah School for Gifted students, and (431) students from public school.The researcher used Bar-On Inventory which consists of (60) item. And the Social academic adaptation scale which Consist of (33) items. The findings indi...
Some comments on `Equation for the second virial coefficient`
Umirzakov, I. H.
The second viral coefficient calculated using the equation suggested in the paper of Kaplun A.B., Meshalkin A.B. Equation for the second virial coefficient published in High temperature high pressure, 1999, Volume 31, pages 253-258 is compared with experimental data for helium, hydrogen, neon, argon, krypton, xenon, carbon dioxide, water, ammonia, methane, ethylene. It is shown the formula cannot describe the temperature dependence of the experimental data on the second virial coefficient for...
Poor adjustment to college life mediates the relationship between drinking motives and alcohol consequences: A look at college adjustment, drinking motives, and drinking outcomes
LaBrie, Joseph W.; Ehret, Phillip J.; Hummer, Justin F.; Prenovost, Katherine
The current study examined whether the relationship between drinking motives and alcohol-related outcomes was mediated by college adjustment. Participants (N=253) completed an online survey that assessed drinking motives, degree of both positive and negative college adjustment, typical weekly drinking, and past month negative alcohol-related consequences. Structural equation modeling examined negative alcohol consequences as a function of college adjustment, drinking motives, and weekly drink...
Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores
DEFF Research Database (Denmark)
Vilhjálmsson, Bjarni J; Yang, Jian; Finucane, Hilary K;
outperforms the approach of pruning followed by thresholding, particularly at large sample sizes. Accordingly, predicted R(2) increased from 20.1% to 25.3% in a large schizophrenia dataset and from 9.8% to 12.0% in a large multiple sclerosis dataset. A similar relative improvement in accuracy was observed...... for three additional large disease datasets and for non-European schizophrenia samples. The advantage of LDpred over existing methods will grow as sample sizes increase....
Comparison of community-onset Staphylococcus argenteus and Staphylococcus aureus sepsis in Thailand: a prospective multicentre observational study
Chantratita, N.; Wikraiphat, C; Tandhavanant, S.; Wongsuvan, G; Ariyaprasert, P.; Suntornsut, P; Thaipadungpanit, J; Teerawattanasook, N.; Jutrakul, Y.; Srisurat, N; Chaimanee, P; Anukunananchai, J.; Phiphitaporn, S; Srisamang, P; Chetchotisakd, P
Staphylococcus argenteus is a globally distributed cause of human infection, but diagnostic laboratories misidentify this as Staphylococcus aureus. We determined whether there is clinical utility in distinguishing between the two. A prospective cohort study of community-onset invasive staphylococcal sepsis was conducted in adults at four hospitals in northeast Thailand between 2010 and 2013. Of 311 patients analysed, 58 (19%) were infected with S. argenteus and 253 (81%) with S. aureus. Most ...
Radiation therapy compared with chemotherapy for consolidation of chemotherapy-induced remission of advanced Hodgkin lymphoma: a study by the Eastern Co-operative Oncology Group (E1476) with > 20 years follow-up
Wiernik, Peter H.; Hong, Fangxin; GLICK, JOHN H.; Bennett, John M
MOPP-Bleo (nitrogen mustard, vincristine, procarbazine, prednisone and bleomycin) induction therapy was given to 253 evaluable patients with Hodgkin lymphoma, stages IIIB, IIIs, or IV. Complete response (CR) occurred in 145 patients (57%) and partial response (PR) in 93 (37%). Of those 238 responders, 178 were randomized to consolidation therapy, and 164 were eligible and analyzable, including 114 CRs [55 patients randomized to ABVD and 59 to radiation therapy (RT)] and 50 partial responders ...
The improvement of old and the application of new techniques in seismometry
International Nuclear Information System (INIS)
The progress in the development of seismic instrumentation has resulted in state-of-the-art instruments capable of attaining a dynamic range of up to 140 dB in a wide frequency range of 2.5-3 decade. Old seismic instruments have been improved to achieve such an aim. Mechanical parts have been replaced with electronics, thus reducing the cost of instruments. The new instruments are capable of working in a wide range of temperatures. (author)
Martin Mellen; Anna Kalafová; Henrieta Arpašová; Miroslava Kačániová; Marcela Capcarova
The aim of present study was to evaluate the functional efficiency of probiotic preparation on selected blood biochemical parameters of ISA Brown hens. Feed in the experimental group of hens was enriched with a probiotic preparation in the dose of 500g.t-1 consisted of freeze-dried cultures: Lactobacillus bulgaricus LAT 187, L. acidophilus LAT 180, L. helveticus LAT 179, L. delbrueckii ssp. Lactis LAT 182, Streptococcus thermophiles LAT 205, Enterococcus faecium E-253 with concentration of 5....
48 CFR 52.212-5 - Contract Terms and Conditions Required To Implement Statutes or Executive Orders-Commercial Items.
... Subcontractor Sales to the Government (SEP 2006), with Alternate I (OCT 1995) (41 U.S.C. 253g and 10 U.S.C. 2402... Privately Owned U.S.-Flag Commercial Vessels (FEB 2006) (46 U.S.C. Appx 1241(b) and 10 U.S.C. 2631). ___(ii....247-64, Preference for Privately Owned U.S.-Flag Commercial Vessels (FEB 2006) (46 U.S.C. Appx...
Weak approximation of second-order BSDEs
Possamaï, Dylan; Tan, Xiaolu
We study the weak approximation of the second-order backward SDEs (2BSDEs), when the continuous driving martingales are approximated by discrete time martingales. We establish a convergence result for a class of 2BSDEs, using both robustness properties of BSDEs, as proved in Briand, Delyon and M\\'{e}min [Stochastic Process. Appl. 97 (2002) 229-253], and tightness of solutions to discrete time BSDEs. In particular, when the approximating martingales are given by some particular controlled Mark...
藤川, 美枝子
The present research examined the relationship between elderly driver's continuance needs by driving school instructors and the necessity of improving the renewal course. The driving instructors examined the relationship between these needs and the attitude in teaching the renewal course. Questionnaires were given to 253 driving school instructors (M=42.9 years, SD=9.07). The questionnaires included: eye sight test, driving aptitude, driving behavior, degree of dementia, evaluation of the eld...
Comparison of Gap in Noise Test Results in Musicians and Non-Musician Controls
Ghassem Mohamadkhani; Mohammad Hossein Nilforoushkhoshk; Ali Zadeh Mohammadi; Soghrat Faghihzadeh; Mahsa Sepehrnejhad
Background and Aim: Main feature of auditory processing abilities is temporal processing including temporal resolution, temporal ordering, temporal integration and temporal masking. Many studies have shown the superiority of musicians in temporal discrimination over non-musicians. In this study we compared temporal processing in musicians and non-musician controls via Gap in Noise (GIN) test.Methods: This cohort study was conducted on 24 musicians with mean age of 25.3 years and 24 normal hea...
Mothers Behaviors about Viewing of Television and TV Ratings System
Kubilay Ceritoglu; Selman Belviranli; Cagla Bilgin; Feyza Bayraktar; Hesna Bulut; Songul A. Vaizoglu; Cagatay Guler
BACKGROUND: Excessive viewing of television results serious negative effects on physical and mental health of children and adolescents. In Turkey, Radio and Television Supreme Council (RTUK) started a TV ratings project to inform parents about program contents on 23rd of April 2006. The objective of this study was to determine mothers behaviors about viewing of television and their knowledge and opinions about TV ratings system. METHODS: This descriptive research was performed among 253...
Water transport by Na+-coupled cotransporters of glucose (SGLT1) and of iodide (NIS). The dependence of substrate size studied at high resolution
DEFF Research Database (Denmark)
Zeuthen, Thomas; Belhage, Bo; Zeuthen, Emil
-analogue alpha-MDG (MW 194); using the larger sugar arbutin (MW 272) this number was reduced by a factor of at least 0.86+/-0.03 (15). For the human SGLT1 the respective numbers were 234+/-12 (18) and 0.85+/-0.8 (7). For NIS, 253+/-16 (12) water molecules were cotransported for each 2 Na+ and 1 thiocyanate (SCN...
Institute of Scientific and Technical Information of China (English)
970233 Detection of excreted circulating antigen(CCA)in urine of infected hosts by means of sandwichstrip-ELISA. LU Ping(陆萍), et al. Dept Parasitol,2nd Med Univ, Shanghai, 200025. Chin J Parasitol &Parasit Dis 1996; 14(4): 253-256. Objective: To set up a simple immunoassay for de-tection of the excreted antigens in host urine.Meth-
The significance of food safety in trade and banning the importation of GMO products into Iran
Rezazadeh, Tahereh; Aghaiypour, Kh.; Heidari, Zohreh
According to legislation in Iran, the importation of transgenic products should be banned due to the lack of strong evidence for the safety of genetically modified foods. Therefore, the detection of genetically modified on importing products should perform by food control laboratories. In this study, specific primers were designed for 35S promoter (500 bp), NOS terminator (253 bp), NPT (470 bp) and GUS (443 bp) for the detection of GMO in 134 imported samples by Polymerase chain reaction. T...
Nazar LUQMAN
(Refer to page 253)Answer: Mitral valve stenosis (Doming of mitral leaflets)The mitral valve is frequently involved in rheumatic heart disease, which is still prevalent in developing countries. Other valves may also be involved. The incidence of rheumatic heart disease is now less common in developed and developing nations. It is notinfrequently encountered in Brunei Darussalam. The mitral valve is usually affected decades following an episode of rheumatic carditis. With time, the rheumatic h...
Optical control of insulin release using a photoswitchable sulfonylurea
Broichhagen, Johannes; Schönberger, Matthias; Cork, Simon C.; Frank, James A.; Marchetti, Piero; Bugliani, Marco; Shapiro, A. M. James; Trapp, Stefan; Rutter, Guy A.; Hodson, David J.; Trauner, Dirk
Sulfonylureas are widely prescribed for the treatment of type 2 diabetes mellitus (T2DM). Through their actions on ATP-sensitive potassium (KATP) channels, sulfonylureas boost insulin release from the pancreatic beta cell mass to restore glucose homeostasis. A limitation of these compounds is the elevated risk of developing hypoglycemia and cardiovascular disease, both potentially fatal complications. Here, we describe the design and development of a photoswitchable sulfonylurea, JB253, which...
Energy Technology Data Exchange (ETDEWEB)
Eichmann, B.; Tjus, J. Becker, E-mail: firstname.lastname@example.com [Institut für Theoretische Physik, Lehrstuhl IV: Plasma-Astroteilchenphysik, Ruhr-Universität Bochum, D-44780 Bochum (Germany)
We present a systematic study of non-thermal electron–proton plasma and its emission processes in starburst galaxies in order to explain the correlation between the luminosity in the radio band and the recently observed gamma luminosity. In doing so, a steady state description of the cosmic-ray (CR) electrons and protons within the spatially homogeneous starburst is considered where continuous momentum losses are included as well as catastrophic losses due to diffusion and advection. The primary source of the relativistic CRs, e.g., supernova remnants, provides a quasi-neutral plasma with a power-law spectrum in momentum where we account for rigidity-dependent differences between the electron and proton spectrum. We examine the resulting leptonic and hadronic radiation processes by synchrotron radiation, inverse Compton scattering, Bremsstrahlung, and hadronic pion production. Finally, the observations of NGC 253, M82, NGC 4945, and NGC 1068 in the radio and gamma-ray bands as well as the observed supernova rate are used to constrain a best-fit model. In the case of NGC 253, M82, and NGC 4945 our model is able to accurately describe the data, showing that: (i) supernovae are the dominant particle accelerators for NGC 253, M82, and NGC 4945, but not for NGC 1068; (ii) all considered starburst galaxies are poor proton calorimeters in which for NGC 253 the escape is predominantly driven by the galactic wind, whereas the diffusive escape dominates in NGC 4945 and M82 (at energies >1 TeV); and (iii) secondary electrons from hadronic pion production are important to model the radio flux, but the associated neutrino flux is below the current observation limit.
Benefits of cryogenic cooling on the operation of a pulsed CO2 laser
Indian Academy of Sciences (India)
Utpal Nundy
The paper presents results of a theoretical model of a pulsed electron beam controlled CO2 laser (EBCL) to investigate the effect of cooling on the laser gas mixture. It is shown that cryogenic cooling can significantly improve the performance of the laser. The efficiency of an EBCL improved from 20% to 25.3% by cooling it to 200 K. The improvement is mainly due to the decrease of thermal population of the CO2 (0 1 0) vibration level.
International Nuclear Information System (INIS)
The document lists the 132 Member States of the Agency as of 1 June 2001. The new Members since the last issue of the list (INFCIRC/2/53) are Central African Republic and Azerbaijan. The dates on which the present 132 Member States became Members are given in an Attachment. It also shows the States whose application for membership of the Agency has been approved by the General Conference but which has not yet deposited an instrument of acceptance of the Statute
Luteal Phase Support in the Intrauterine Insemination (IUI) Cycles: A Randomized Double Blind, Placebo Controlled Study
Batool Hossein Rashidi; Fatemeh Davari Tanha; Haleh Rahmanpour; Mahya Ghazizadeh
Objective: To evaluate the impact of luteal phase support with vaginal progesterone on pregnancy rates in the intrauterine insemination (IUI) cycles, stimulated with clomiphene citrate and human menopausal gonadotropin (hMG), in sub fertile couples. Materials and methods: This prospective, randomized, double blind study was performed in a tertiary infertility center from March 2011 to January 2012. It consisted of 253 sub fertile couples undergoing ovarian stimulation for IUI cycles. They und...
Renewable energy sources and their contribution to the gross domestic energy consumption in Italy in the year 1994; Censimento per il territorio italiano dei dati relativi alle fonti rinnovabili di energia ed al loro contributo al bilancio energetico per l`anno 1994
Energy Technology Data Exchange (ETDEWEB)
Menna, P.; Manzo, R. [ENEA, Centro Ricerche Portici, Naples (Italy). Dip. Energia
The gross domestic energy consumption in 1994 (including bunkers) decreased to 165.8 Mtoe from the 1993 figure of 166.6 Mtoe. At the same time the overall electricity demand reached 253.6 TWh from 246.6 TWh, closely reflecting the 2 contribution of renewable energy sources (hydroelectricity, geothermal, biomasses, solar, wind) to the national energy consumption has been 9 1994. It represented more than 34% of the domestic energy production.
Impairment of Colour Vision in Diabetes with No Retinopathy: Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular Genetics Study (SNDREAMS- II, Report 3)
Gella, Laxmi; Raman, Rajiv; Kulothungan, Vaitheeswaran; Pal, Swakshyar Saumya; Ganesan, Suganeswari; Sharma, Tarun
Purpose To assess impairment of colour vision in type 2 diabetics with no diabetic retinopathy and elucidate associated risk factors in a population-based cross-sectional study. Methods This is part of Sankara Nethralaya Diabetic Retinopathy Epidemiology and Molecular-genetics Study (SN-DREAMS II) which was conducted between 2007–2010. FM 100 hue-test was performed in 253 subjects with no clinical evidence of diabetic retinopathy. All subjects underwent detailed ophthalmic evaluation includin...
Domain Modeling: NP_060052.3 [SAHG[Archive
Lifescience Database Archive (English)
Full Text Available Embryo Attachment and Implantation p1zuob_ chr1/NP_060052.3/NP_060052.3_apo_248-387.pdb blast 250V,253T,254D,257M,258K,260L,261R,264Y,278L,281D,282S,283L,284Y,322K 351C 0 ... ...NP_060052.3 chr1 Structure of Human Ubiquitin-Conjugating Enzyme (UBCi) Involved in
Children With Conduct Problems and Co-occurring ADHD: Behavioral Improvements Following Parent Management Training
Bjørnebekk, Gunnar; Kjøbli, John; Ogden, Terje
To scale up evidence-based treatment of conduct problems, parent management training, Oregon model (PMTO) has been disseminated throughout Norway. This study examined whether Attention Deficit Hyperactivity Disorder (ADHD) predicted the outcomes of PMTO. Of 253 children and families, 97 were reported to have an ADHD diagnosis. Although different at intake, the groups with and without ADHD had close to an equal change in behavioral status following treatment. Maternal depression and family inc...
Directory of Open Access Journals (Sweden)
Cecilia Mercado Torres
Full Text Available Los dilemas del reasentamiento. Debates y experiencias de la Mesa Nacional de Diálogos sobre Reasentamiento de Población. Margarita Serje y Stefano Anzellini (Compiladores; Universidad de los Andes, Facultad de Ciencias Sociales, ceso, Departamento de Antropología, Facultad de Arquitectura y Diseño, Centro de Estudios Socioculturales e Internacionales, Bogotá, 2012, 253 págs., il.
Moth Fauna of Gageodo Island in the Southwestern Sea, Korean Peninsula, including Seven Unrecorded Species (Lepidoptera)
Choi, Sei-Woong; Kim, Sung-Soo; An, Jeong-Seop; Kwon, Tae-Sung
We surveyed moths on Gageodo island in the southwestern sea of the Korean Peninsula over three years (2009, 2012, 2013) and found a total of 253 species in 18 families. Geometridae had the greatest species richness, with 63 species, followed by Noctuidae, Erebidae, Crambidae and Sphingidae. The annual changes in species richness and abundance were not different and seasonal occurrence of species showed a unimodal pattern in which the numbers of species and individuals increased from April and...
Moving on From Millennials: Preparing for Generation Z.
Shatto, Bobbi; Erwin, Kelly
Much has been written about teaching Millennials; however, little has been discussed about Generation Z-those just entering college. Nursing instructors must adapt to the upcoming generation's mobile tech-savviness and self-directed learning, which often is accompanied by a lack of critical thinking skills. Teaching strategies and incorporating technology are highlighted. J Contin Educ Nurs. 2016;47(6):253-254. PMID:27232222
Automated continuous monitoring of inorganic and total mercury in wastewater and other waters by flow-injection analysis and cold-vapour atomic absorption spectrometry
Birnie, S. E.
An automated continuous monitoring system for the determination of inorganic and total mercury by flow-injection analysis followed by cold-vapour atomic absorption spectrometry is described. The method uses a typical flow-injection manifold where digestion and reduction of the injected sample takes place. Mercury is removed by aeration from the flowing stream in a specially designed air-liquid separator and swept into a silica cell for absorption measurement at a wavelength of 253.7 nm. A cal...
Hard X-ray spectral and timing properties of IGR J17454-2919 consistent with a black hole in the hard state
DEFF Research Database (Denmark)
Tendulkar, Shriharsh P.; Bachetti, Matteo; Tomsick, J.;
frequencies. The Lorentzian has a width of 2 Hz and a fractional rms of 25+/-3%. The hard power-law index, the high energy of the cutoff, and the level of variability all are consistent with properties expected for an accreting black hole in the hard state. While we cannot completely rule out the possibility...... of a low magnetic field neutron star, a black hole is more likely....
High-performance vessels from an aromatic polyamide fiber/epoxy composite
Chiao, T. T.; Hamstad, M. A.
The investigation reported is concerned with the development of a filament-wound, ultralightweight composite vessel for the containment of cryogenic propellants and pressurant gases. The vessels are to be used within an operational temperature range from -253 C to ambient temperature. The fiber used for the process is Kevlar 49. The design and the fabrication of specimens and vessels are discussed along with the results obtained in a testing program.
An investigation of the relationship between achievement goal orientations and the use of stress coping strategies with canonical correlation
Çetin, Bayram; Akın, Ahmet
The aim of this research was to examine the relationship between achievement goal orientations and the use of stress-coping strategies among college students. The sample consisted of 532 university students who were enrolled in different programs at Sakarya University, in Turkey. Of the participants, 279 were female and 253 were male. To assess strategies typically used in coping with stressful situations, the Coping Scale (Ozbay & Olivarez, 1999) and to measure achievement goal orientations ...
Cardiovascular disease in Navajo Indians with type 2 diabetes.
Hoy, W; Light, A; Megill, D
Rates of both type 2 diabetes and cardiovascular disease have risen sharply in recent years among Navajo Indians, the largest reservation-based American Indian tribe, but the association between the two conditions is not entirely clear. Rates of cardiovascular disease and some possible associations in several hundred diabetic and non-diabetic Navajos were estimated. Nearly one-third (30.9 percent) of those with diabetes had formal diagnoses of cardiovascular disease--25.3 percent had heart di...
Chinese users' preference for web browser icons.
Shen, Siu-Tsen; Prior, Stephen D.; Chen, Kuen-Meau; Fang, Te-Hua
This paper compares the perspicacity, appropriateness and preference of web browser icons from leading software providers with those of a culture-specific design. The history and future direction of web browsers is outlined, together with the implications for the future growth of Chinese internet users. China, with its rapidly expanding young netizens has now overtaken the USA in terms of the number of internet users (253 million) and we predict it will reach saturation (≈70% internet penetra...
Radiation Measurements of the Mars Science Lab Radiation Assessment Detector (MSL-RAD) on the Surface of Mars
Reitz, Guenther; Matthiä, Daniel; Hassler, Donald M.; Wimmer-Schweingruber, Robert; Ehresmann, Bent; Zeitlin, Cary; Guo, Jingnan; Koehler, Jan
The Radiation Assessment Detector (RAD) was designed to characterize the radiation environment as "Life Limiting Factor" to habitability and to help to prepare for future human exploration of Mars. The Mars Science Laboratory spacecraft (MSL), containing the Curiosity rover, in which RAD is integrated, was launched to Mars on November 26, 2011. Although not part of the mission planning, RAD was operated already during the 253 day and 560 million km cruise to Mars and made the first detailed a...
Job conditions, psychological climate, and affective commitment as predictors of intention to quit among two groups of bank employees in Nigeria
Balogun MR; Adetula, Gabriel A.; Olowodunoye, Stella, A.
This study examined the extent to which job conditions (job demands and job control), psychological climate, and affective commitment predict turnover intention among Tellers and Interpersonal Relation Officers in some Nigerian Banks and whether affective commitment mediate the relationship between psychological climate and turnover intention. Five hundred and nineteen(tellers = 321, IRO = 198)bank employees (266 males and 253 females) whose ages ranged from 19 to 65 years with a mean of 34.0...
Luminescence of powdered uranium glasses
Eubanks, A. G.; Mcgarrity, J. M.; Silverman, J.
Measurement of cathodoluminescence and photoluminescence efficiencies in powdered borosilicate glasses having different particle size and different uranium content. Excitation with 100 to 350 keV electrons and with 253.7 nm light was found to produce identical absolute radiant exitance spectra in powdered samples. The most efficient glass was one containing 29.4 wt% B2O3, 58.8 wt% SiO2, 9.8 wt% Na2O and 2.0 wt% UO2.
Effects of drought stress on antioxidant enzymes in seedlings of different wheat genotypes
International Nuclear Information System (INIS)
The aim of this experiment was to study the relationship between the physiological and biochemical indices and drought resistance of different wheat varieties. The response parameters evaluated were: relative water content (RWC), malondialdehyde content (MDA) and isozymes including superoxide dismutase (SOD), catalase (CAT) and peroxidase (POD) in seedlings of four genotypes, including Changwu134, Xinong2208, Xinong928 and Shaan253. The wheat seedlings were subjected by -1.0MPa PEG-6000 solution for 1-6 d in hydroponic condition and the quantities of antioxidant enzymes was measured. The results showed that the expression of SOD isozymes in seedling leaves was strongest in Changwu134 and weakest in Shaan253. CAT isozymes were induced well and increased readily in Changwu134 and Xinong928 seedling leaves than in Xinong2208 and Shaan253 during drought stress. The expression pattern of POD isozymes was similar to CAT. It is well known that SOD, CAT and POD enzymes play a significant role in determining response of wheat genotypes to drought stress. The results of this study suggested that the amount of antioxidant enzymes determine drought stress tolerance in wheat. (author)
Characterization of aquatic humic substances to DBPs formation in advanced treatment processes for conventionally treated water.
Kim, Hyun-Chul; Yu, Myong-Jin
An advanced water treatment demonstration plant consisted of ozone/granular activated carbon processes was operated to study feasibility of the processes. Natural organic matter (NOM) from raw and process waters at the demonstration plant was isolated into humic and non-humic fractions by physicochemical fractionation method to investigate characteristics of humic fraction (i.e., humic substances, HS) as a predominant haloform reactant. Ozone did not significantly oxidize the carboxylic fraction (from 39.1 to 35.9%), while GAC removed some of the carboxylic fraction (from 35.9 to 29.1%). Formation potential of trihalomethanes (THMs) as compared to haloacetic acids formation potential (HAAFP) was highly influenced by HS. Higher yields of THMs resulted from chlorination of HS with a higher phenolic content and phenolic fraction in the HS gradually decreased from 60.5% to 15.8% through the water treatment. The structural and functional changes of HS were identified by elemental, Fourier-transform infrared (FT-IR) and proton nuclear magnetic resonance ((1)H NMR) analyses, and these results were mutually consistent. The functional distribution data obtained by using A-21 resin could be used to support the interpretation of data obtained from the spectroscopic analyses. Decreases in ratio of UV absorbance at 253 nm and 203 nm (A(253)/A(203)) and DBPFPs/DOC showed consistent trends, therefore, A(253)/A(203) ratio may be a good indicator for the disinfection by-product formation potentials (DBPFPs).
Activity of the Vascular-Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid against Human Head and Neck Carcinoma Xenografts
Directory of Open Access Journals (Sweden)
Mukund Seshadri
Full Text Available Head and neck squamous cell carcinomas (HNSCC constitute a majority of the tumors of the upper aerodigestive tract and continue to present a significant therapeutic challenge. To explore the potential of vascular-targeted therapy in HNSCC, we investigated the antivascular, antitumor activity of the potent vascular-disrupting agent (VDA 5,6-dimethylxanthenone-4-acetic acid (DMXAA against two HNSCC xenografts with markedly different morphologic and vascular characteristics. Athymic nude mice bearing subcutaneous FaDu (human pharyngeal squamous cell carcinoma and A253 (human submaxillary gland epidermoid carcinoma tumors were administered a single dose of DMXAA (30 mg/kg, i.p. Changes in vascular function were evaluated 24 hours after treatment using contrast-enhanced magnetic resonance imaging (MRI and immunohistochemistry (CD31. Signal enhancement (E and change in longitudinal relaxation rates (ΔR1 were calculated to measure alterations in vascular perfusion. MRI showed a 78% and 49% reduction in vascular perfusion in FaDu and A253 xenografts, respectively. CD31-immunostaining of tumor sections revealed three-fold (FaDu and two-fold (A253 reductions in microvessel density (MVD 24 hours after treatment. DMXAA was equally effective against both xenograffs, with significant tumor growth inhibition observed 30 days after treatment. These results indicate that DMXAA may be beneficial in the management of HNSCC, alone or in combination with other treatments.
LABOCA observations of nearby, active galaxies
Weiss, A; Guesten, R; Menten, K M; Schuller, F; Siringo, G; Kreysa, E
We present large scale 870 micron maps of the nearby starburst galaxies NGC253, NGC4945 and the nearest giant elliptical radio galaxy Centaurus A (NGC 5128) obtained with the newly commissioned Large Apex Bolometer Camera (LABOCA) operated at the APEX telescope. Our continuum images reveal for the first time the distribution of cold dust at a angular resolution of 20" across the entire optical disks of NGC253 and NGC4945 out to a radial distance of 10' (7.5 kpc). In NGC5128 our LABOCA image also shows, for the first time at submillimeter wavelengths, the synchrotron emission associated with the radio jet and the inner radio lobes. From an analysis of the 870 micron emission in conjunction with ISO-LWS, IRAS and long wavelengths radio data we find temperatures for the cold dust in the disks of all three galaxies of 17-20 K, comparable to the dust temperatures in the disk of the Milky Way. The total gas mass in the three galaxies is determined to be 2.1, 4.2 and 2.8 x 10^9 solar masses for NGC253, NGC4945 and N...
Are apes inequity averse? New data on the token-exchange paradigm.
Bräuer, Juliane; Call, Josep; Tomasello, Michael
Recent studies have produced mixed evidence about inequity aversion in nonhuman primates. Brosnan et al. [Proceedings of the Royal Society of London. Series B. Biological Sciences 272:253-258, 2005] found inequity aversion in chimpanzees and argued that effort is crucial, if subjects are to evaluate how they are rewarded in comparison to a competitor for an identical performance. In this study we investigated inequity aversion with chimpanzees, bonobos and orangutans, using the method of Brosnan et al. [Proceedings of the Royal Society of London. Series B. Biological Sciences 272:253-258, 2005] after introducing some methodological improvements. Subjects always received a less-preferred food in exchange for a token, whereas the competitor received either the same type of food for their token (equity) or a more favored food for it (inequity). Apes did not refuse more of the less-preferred food when a competitor had received the more favored food. Thus, with an improved methodology we failed to reproduce the findings of Brosnan et al. [Proceedings of the Royal Society of London. Series B. Biological Sciences 272:253-258, 2005] that apes show inequity aversion. PMID:19021260
Influence of relative humidity and temperature on the production of pinonaldehyde and OH radicals from the ozonolysis of α-pinene
Directory of Open Access Journals (Sweden)
Y. Iinuma
Full Text Available The ozonolysis of α-pinene has been investigated under dry and humid conditions in the temperature range of 243–303 K. The results provided new insight into the role of water and temperature in the degradation mechanism of α-pinene and in the formation of secondary organic aerosols (SOA. The SOA yields were higher at humid conditions than at dry conditions. The water induced gain was largest for the lowest temperatures investigated (243 and 253 K. The increase in the SOA yields was dominated by water (and temperature effects on the organic product distribution, whilst physical uptake of water was negligible. This will be demonstrated for the example of pinonaldehyde (PA which was formed as a major product in the humid experiments with total molar yields of 0.30±0.06 at 303 K and 0.15±0.03 at 243 K. In the dry experiments the molar yields of PA were only 0.07±0.02 at 303 K and 0.02±0.02 at 253 K. The observed partitioning of PA as a function of the SOA mass present at 303 K limited the effective vapour pressure of pure PA pPA0 to the range of 0.01–0.001 Pa, 3–4 orders of magnitude lower than literature values. The corresponding mass partitioning coefficient was determined to KPA=0.005±0.004 m3 μg−1 and the total mass yield αPAtotal=0.37±0.08. At 303 K PA preferably stayed in the gas-phase, whereas at 253 K and 243 K it exclusively partitioned into the particulate phase. PA could thus account at least for half of the water induced gain in SOA mass at 253 K. The corresponding effect was negligible at 303 K because the PA preferably remained in the gas-phase. The yield of OH radicals, which were produced in the ozonolysis, was indirectly determined by means of the yield of cyclohexanone formed in the reaction of OH radicals with cyclohexane. OH yields of the α-pinene ozonolysis were determined to 0.67±0.17 for humid and 0.54±0.13 for dry conditions at 303 K, indicating a water dependent path of OH radical formation. For 253 and
Influence of relative humidity and temperature on the production of pinonaldehyde and OH radicals from the ozonolysis of α-pinene
Directory of Open Access Journals (Sweden)
Y. Iinuma
Full Text Available The ozonolysis of α-pinene has been investigated under dry and humid conditions in the temperature range of 243–303 K. The results provided new insight into the role of water and temperature in the degradation mechanism of α-pinene and in the formation of secondary organic aerosols (SOA. The SOA yields were higher at humid conditions than at dry conditions. The water induced gain was largest for the lowest temperatures investigated (243 and 253 K. The increase in the SOA yields was dominated by water (and temperature effects on the organic product distribution, whilst physical uptake of water was negligible. This will be demonstrated for the example of pinonaldehyde (PA which was formed as a~major product in the humid experiments with total molar yields of 0.30±0.06 at 303 K and 0.15±0.03 at 243 K. In the dry experiments the molar yields of PA were only 0.07±0.02 at 303 K and 0.02±0.02 at 253 K. The observed partitioning of PA as a function of the SOA mass present at 303 K limited the effective vapour pressure of pure PA pPA0 to the range of 0.01–0.001 Pa, 3–4 orders of magnitude lower than literature values. The corresponding mass partitioning coefficient was determined to KPA=0.005±0.004 m3/μg and the total mass yield αPA.total=0.37±0.08. At 303 K PA preferably stayed in the gas-phase, whereas at 253 K and 243 K it exclusively partitioned into the particulate phase. PA could thus account at least for half of the water induced gain in SOA mass at 253 K. The corresponding effect was negligible at 303 K because the PA preferably remained in the gas-phase. The yield of OH radicals, which were produced in the ozonolysis, was indirectly determined by means of the yield of cyclohexanone formed in the reaction of OH radicals with cyclohexane. OH yields of the α-pinene ozonolysis were determined to 0.67±0.17 for humid and 0.54±0.13 for dry conditions at 303 K, indicating a water dependent path of OH radical formation. For 253 and 243
Especially for High School Teachers
Howell, J. Emory
Ideas and Resources in This Issue This issue contains a broad spectrum of topics of potential interest to high school teachers, including chemical safety, history, demonstrations, laboratory activities, electrochemistry, small group learning, and instructional software. In his report on articles published recently in The Science Teacher, Steve Long includes annotated references from that journal, and also from JCE, that provide timely and practical information (pp 21-22). The chemical significance of several anniversaries that will occur in the year 2000 are discussed in an article by Paul Schatz (pp 11-14). Scientists and inventors mentioned include Dumas, Wöhler, Goodyear, Joliot-Curie, Krebs, Pauli, Kjeldahl, and Haworth. Several discoveries are also discussed, including development of the voltaic pile, the use of chlorine to purify water, and the discovery of element 97, berkelium. This is the fourth consecutive year that Schatz has written an anniversaries article (1-3). Although most readers probably do not plan to be teaching in the years 2097-3000, these articles can make a nice addition to your file of readily available historical information for use now in meeting NSES Content Standard G (4). In contrast to the short historical summaries, an in-depth account of the work of Herman Boerhaave is provided by Trinity School (NY) teacher Damon Diemente. You cannot recall having heard of Boerhaave? Diemente explains in detail how Boerhaave's scientific observations, imperfect though they were, contributed significantly to the understanding of temperature and heat by scientists who followed him. Chemical demonstrations attract the interest of most of us, and Kathy Thorsen discusses several that appeared in Chem 13 News during the past year (pp 18-20). Included are demonstrations relating to LeChâtelier's principle, electronegativity, and the synthesis and reactions of carbon monoxide. Ideas for investigating the hydrophobic nature of Magic Sand are given in JCE
2010 Neutron Review: ORNL Neutron Sciences Progress Report
Energy Technology Data Exchange (ETDEWEB)
Bardoel, Agatha A [ORNL; Counce, Deborah M [ORNL; Ekkebus, Allen E [ORNL; Horak, Charlie M [ORNL; Nagler, Stephen E [ORNL; Kszos, Lynn A [ORNL
During 2010, the Neutron Sciences Directorate focused on producing world-class science, while supporting the needs of the scientific community. As the instrument, sample environment, and data analysis tools at High Flux Isotope Reactor (HFIR ) and Spallation Neutron Source (SNS) have grown over the last year, so has promising neutron scattering research. This was an exciting year in science, technology, and operations. Some topics discussed are: (1) HFIR and SNS Experiments Take Gordon Battelle Awards for Scientific Discovery - Battelle Memorial Institute presented the inaugural Gordon Battelle Prizes for scientific discovery and technology impact in 2010. Battelle awards the prizes to recognize the most significant advancements at national laboratories that it manages or co-manages. (2) Discovery of Element 117 - As part of an international team of scientists from Russia and the United States, HFIR staff played a pivotal role in the discovery by generating the berkelium used to produce the new element. A total of six atoms of ''ununseptium'' were detected in a two-year campaign employing HFIR and the Radiochemical Engineering Development Center at Oak Ridge National Laboratory (ORNL) and the heavy-ion accelerator capabilities at the Joint Institute for Nuclear Research in Dubna, Russia. The discovery of the new element expands the understanding of the properties of nuclei at extreme numbers of protons and neutrons. The production of a new element and observation of 11 new heaviest isotopes demonstrate the increased stability of super-heavy elements with increasing neutron numbers and provide the strongest evidence to date for the existence of an island of enhanced stability for super-heavy elements. (3) Studies of Iron-Based High-Temperature Superconductors - ORNL applied its distinctive capabilities in neutron scattering, chemistry, physics, and computation to detailed studies of the magnetic excitations of iron-based superconductors (iron
Características agronômicas e o estado nutricional de cultivares de girassol irrigado Agronomic characteristics and nutritional status of irrigated sunflower cultivars
Directory of Open Access Journals (Sweden)
Leonardo A. de Aquino
Full Text Available Objetivou-se, neste trabalho, avaliar o estado nutricional, caracteres agronômicos e a produtividade de cultivares de girassol sob irrigação. Os cultivares Embrapa 122 V-2000, Hélio 250, Hélio 251, Hélio 253, Hélio 358, Hélio 360, IAC Iarama, Dow Agroscience M 734 e MG 02, foram semeados em blocos ao acaso, com quatro repetições. O número de folhas por planta no florescimento foi maior nos híbridos Hélio 250, Hélio 251, Hélio 253, Hélio 358, Hélio 360, Dow Agroscience M 734 e MG 02, em relação aos cultivares de polinização aberta Embrapa 122 V-2000 e IAC Iarama. Os teores foliares de N, P, K, Ca, Mg e S foram 40,91; 3,51; 35,91; 33,91; 6,23 e 7,88 g kg-1, respectivamente. Os cultivares Embrapa 122 V-2000 e IAC-Iarama apresentaram teor de P na folha índice menor que os demais cultivares. Os teores foliares de Zn, Cu, Fe e o Mn foram 75,15; 24,11; 98,39 e 348,10 mg kg-1, respectivamente. O teor médio de B na folha índice nos híbridos e nas variedades de polinização aberta foi de 119,25 e 140,35 mg kg-1, respectivamente. Os cultivares Hélio 250, Hélio 251, Hélio 253, Hélio 358, Hélio 360, Dow Agroscience M 734 e MG 02 apresentaram maior produtividade que o Embrapa 122 V-2000 e o IAC Iarama.This work aimed to assess nutritional status, agronomic characteristics, and productivity of sunflower cultivars under irrigation. Embrapa 122 V-2000, Hélio 250, Hélio 251, Hélio 253, Hélio 358, Hélio 360, IAC Iarama, and Dow Agroscience M 734 and MG 02 cultivars were sown in randomized block design with four replications. The number of leaves per plant in full bloom was higher in hybrid Hélio 250, Hélio 251, Hélio 253, Hélio 358, Hélio 360 and Dow Agroscience MG 734 and M 02 related to open-pollinated cultivars Embrapa 122 V-2000 and IAC Iarama. Foliar contents of N, P, K, Ca, Mg, and S were 40.91, 3.51, 35.91, 33.91, 6.23, and 7.88 g kg-1, respectively. Embrapa 122 V-2000 and IAC-Iarama cultivars showed an average
Proton Single-Particle States In The Heaviest Actinide Nuclei
International Nuclear Information System (INIS)
The level structure of 249Bk has been investigated by measuring the γ-ray spectra following the α decay of a chemically and isotopically pure 253Es sample. Alpha-gamma coincidence measurement was performed using a Si detector for α particles and a 25% Ge detector for γ rays. A gamma-gamma coincidence measurement was performed with the Gammasphere spectrometer. The Es sample was obtained by extracting the 253Es which grew in a 253Cf source material produced in the High Flux Isotope Reactor (HFIR) at Oak Ridge National Laboratory. Additional information on the 249Bk levels was obtained from the study of γ rays produced in the β- decay of 249Cm. The 249Cm sample was produced by neutron irradiation of 248Cm. Using the results of the present study and the results of previous 248Cm(α,t) and 248Cm(3He,d) reaction spectra, the following single-particle states have been identified in 249Bk: 7/2+[633], 0.0 keV; 3/2-[521], 8.78 keV; 1/2+[400], 377.55 keV: 5/2+[642], 389.17 keV; 1/2-[530], 569.19 keV; 1/2-[521], 643.0 keV; 5/2-[523], 672.8 keV; 9/2+[624], 1075.1 keV. Four vibrational bands were identified at 767.9, 932.2, 1150.7 and 1223.0 keV with tentative assignments of {7/2+[633]x1-}9/2-, {7/2+[633]x0-}7/2-, {7/2+[633]x1-}5/2- and {7/2+[633]x0+}7/2+, respectively
Compact Radio Sources in NGC 660
Wiercigroch, A. B.
The nuclei of starburst galaxies are often obscured by dust and hence are probed best in non-visual wavelength regimes such as the infrared and radio. For example, radio studies of classical starburst galaxies such as NGC 253 and M82 have identified ~ 50 compact sources in each galaxy. One of the purposes of this type of observing program has been to classify the compact radio sources as H II regions or radio supernovae, and to estimate the supernova rates. If obtainable, spectral indices are used to identify the compact structures; otherwise supporting evidence or assumptions are needed. NGC 660, located at a distance of 7.5 Mpc, is a strong candidate for a search for compact radio sources. It is a relatively strong infrared emitter, has far infrared colors similar to NGC 253 and M82, and shows several peaks in published Very Large Array (VLA) maps at 6 cm and 20 cm. We therefore observed NGC 660 at 3.6 cm in the A-configuration of the VLA on 1995 July 13--14. Total integration time on-source was 4.8 hrs. The image shows a large family ( ~ 20) of compact radio structures with a flux density range of 0.1--3.4 mJy, three of which have fluxes > 2.0 mJy. The source luminosities are comparable to those of the stronger sources in M82 and NGC 253, typically a few times more powerful than Cas A. A number of the compact sources appear to lie along a ring projected against the more diffuse radio emission in the galaxy's nuclear region. The work described in this paper was carried out by the Jet Propulsion Laboratory, California Institute of Technology, under contract with the National Aeronautics and Space Administration.
Exergy and energy analysis of three stage auto refrigerating cascade system using Zeotropic mixture for sustainable development
International Nuclear Information System (INIS)
Highlights: • Zeotropic mixture of R290/R23/R14 works with 22.6% increased exergic efficiency. • Zeotropic mixture of mass fraction 0.218:0.346:0.436 offers COP of 0.253. • Since emphasis on COP, evaporating temperature 0.253 COP became the only alternate. • This is the only alternate refrigerant mixture for three stage ARC system at −97 °C. - Abstract: The Zeotropic mixture of environment friendly refrigerants (HC's and HFC's) being the only alternatives for working fluid in low temperature refrigeration system and hence three stage auto refrigerating cascade (ARC) system was studied for the existence using two combinations of (R290/R23/R14, R1270/R170/R14) three component Zeotropic mixture of five different refrigerants. The exergy analysis confirmed the existence of three stage ARC system. The performances of the system like Coefficient of Performance (COP), exergy lost, exergic efficiency, efficiency defect and the evaporating temperature achieved were investigated for different mass fractions in order to verify the effect of mass fraction on them. In accordance with the environmental issues and the process of sustainable development, the three component Zeotropic mixture of R290/R23/R14 with the mass fraction of 0.218:0.346:0.436 was performing better and hence can be suggested as an alternative refrigerant for three stage ARC system operating at very low evaporating temperature in the range of 176 K (−97 °C) at COP of 0.253 with 58.5% exergic efficiency (comparatively 22.6% increased value)
Human anti-plague monoclonal antibodies protect mice from Yersinia pestis in a bubonic plague model.
Directory of Open Access Journals (Sweden)
Xiaodong Xiao
Full Text Available Yersinia pestis is the etiologic agent of plague that has killed more than 200 million people throughout the recorded history of mankind. Antibiotics may provide little immediate relief to patients who have a high bacteremia or to patients infected with an antibiotic resistant strain of plague. Two virulent factors of Y. pestis are the capsid F1 protein and the low-calcium response (Lcr V-protein or V-antigen that have been proven to be the targets for both active and passive immunization. There are mouse monoclonal antibodies (mAbs against the F1- and V-antigens that can passively protect mice in a murine model of plague; however, there are no anti-Yersinia pestis monoclonal antibodies available for prophylactic or therapeutic treatment in humans. We identified one anti-F1-specific human mAb (m252 and two anti-V-specific human mAb (m253, m254 by panning a naïve phage-displayed Fab library against the F1- and V-antigens. The Fabs were converted to IgG1s and their binding and protective activities were evaluated. M252 bound weakly to peptides located at the F1 N-terminus where a protective mouse anti-F1 mAb also binds. M253 bound strongly to a V-antigen peptide indicating a linear epitope; m254 did not bind to any peptide from a panel of 53 peptides suggesting that its epitope may be conformational. M252 showed better protection than m253 and m254 against a Y, pestis challenge in a plague mouse model. A synergistic effect was observed when the three antibodies were combined. Incomplete to complete protection was achieved when m252 was given at different times post-challenge. These antibodies can be further studied to determine their potential as therapeutics or prophylactics in Y. pestis infection in humans.
Structures of trehalose synthase from Deinococcus radiodurans reveal that a closed conformation is involved in catalysis of the intramolecular isomerization.
Wang, Yung Lin; Chow, Sih Yao; Lin, Yi Ting; Hsieh, Yu Chiao; Lee, Guan Chiun; Liaw, Shwu Huey
Trehalose synthase catalyzes the simple conversion of the inexpensive maltose into trehalose with a side reaction of hydrolysis. Here, the crystal structures of the wild type and the N253A mutant of Deinococcus radiodurans trehalose synthase (DrTS) in complex with the inhibitor Tris are reported. DrTS consists of a catalytic (β/α)8 barrel, subdomain B, a C-terminal β domain and two TS-unique subdomains (S7 and S8). The C-terminal domain and S8 contribute the majority of the dimeric interface. DrTS shares high structural homology with sucrose hydrolase, amylosucrase and sucrose isomerase in complex with sucrose, in particular a virtually identical active-site architecture and a similar substrate-induced rotation of subdomain B. The inhibitor Tris was bound and mimics a sugar at the -1 subsite. A maltose was modelled into the active site, and subsequent mutational analysis suggested that Tyr213, Glu320 and Glu324 are essential within the +1 subsite for the TS activity. In addition, the interaction networks between subdomains B and S7 seal the active-site entrance. Disruption of such networks through the replacement of Arg148 and Asn253 with alanine resulted in a decrease in isomerase activity by 8-9-fold and an increased hydrolase activity by 1.5-1.8-fold. The N253A structure showed a small pore created for water entry. Therefore, our DrTS-Tris may represent a substrate-induced closed conformation that will facilitate intramolecular isomerization and minimize disaccharide hydrolysis.
Youth aggression and bullying: Challenges for pastoral care workers
PUBLISHED A study of over 15,000 6th-10th graders estimated that approximately 3.7 million youths engage in, and more than 3.2 million are victims of moderate or serious bullying each year in the US (Nansel, et al., 2001). While between 1994 and 1999 there were 253 violent deaths in school in the US, 51 casualties were the result of multiple death events. Bullying is often a factor in such schools-related deaths (Anderson, et al. 2001). These and other statistics clearly attest to the p...
Retreived bacteria from Noctiluca miliaris (green) bloom of the northeastern Arabian Sea
Institute of Scientific and Technical Information of China (English)
BASU Subhajit; MATONDKAR SG Prabhu; FURTADO Irene
In recent years,seasonal blooms of the dinoflagellate Noctiluca miliaris have appeared in the open-waters of the northern Arabian Sea (NAS).This study provides the first characterization of bacteria from a seasonal bloom of green Noctiluca ofNAS (20°N-17°N and 64°E-70°E),during the spring-inter-monsoon cruise ofSagar Sampada 253,in March 2007.Bacterial growth as assessed by most-probable number (MPN) and plate counts,revealed 'variable-physiotypes' over a wide range of salinities (0%-25% w/v NaC1),pH levels (5-8.5),and organic nutrient strengths,in comparison to non-bloom waters.MPN indices of bacteria in surface waters of bloom stations *DWK and *PRB,corresponded to (3.08-4.41)× 103 cells/mL at 3.5%NaC1 (w/v),and (2.82-9.49)× 102 cells/mL at 25% (w/v) NaC1 in tryptone-yeast extract broth (TYE).Plate counts were (1.12-4) × 106 CFU/mL at 0% (w/v) NaCl,(1.28-3.9) × 106 CFU/mL at 3.5% (w/v) NaC1,and (0.4-7)× 104 CFU/mL at 25% NaC1 (w/v) on TYE.One-tenth-strength Zobell's gave (0.6-3.74)× 105 CFU/mL at pH 5 to (3.58-7.5)× 105 CFU/mL at pH 8.5.These bacteria were identified to the genera Bacillus,Cellulomonas,Staphylococcus,Planococcus,Dietzia,Virgibacillus,Micrococcus,Sporosarcinae,Leucobacter,and Halomonas.The identity of three strains (GUFBSS253N2,GUFBSS253N30,and GUFBSS253N84) was confirmed through 16S rDNA sequence homology as Bacillus cohnii,Bacillusflexus,and Bacillus cereus.The ~2-3-fold higher plate counts of culturable bacteria from the open-waters of the NAS indicate that these bacteria could critically determine the biogeochemical dynamics of the bloom and its milieu.The role of these bacteria in sustaining/terminating the bloom is under evaluation.
Curso clínico y pronóstico a un año de una cohorte de prematuros dados de alta con oxígeno domiciliario en bogotá, colombia
Charpak, Nathalie; Ruiz, Juan Gabriel; Motta, Sylvia
Objetivo Documentar el curso clínico y pronóstico de una cohorte de niños prematuros dados de alta con oxígeno domiciliario en Bogotá, Colombia. Método Cohorte prospectiva de 194 prematuros de 34 o menos semanas de edad gestacional (EG) al nacer, egresados de 12 unidades neonatales con oxígeno suplementario, seguidos hasta la edad corregida de 12 meses para determinar supervivencia, crecimiento, desarrollo y morbilidad. Resultados 49 niños (25,3 %) tenían una oxigenodependencia leve y 145 ...
Interpretation of pile-oscillation measurements by the integral data assimilation technique
International Nuclear Information System (INIS)
The Integral Data Assimilation (IDA) was designed to deduce values of infinite dilute neutron cross-sections from specific integral measurements. Performances of the IDA procedure are demonstrated with pile-oscillation measurements carried out on 155Gd in the pool type reactor MINERVE (CEA Cadarache, France). At low neutron energies, the Integral Data Assimilation is based on the Neutron Resonance Shape Analysis technique routinely used in neutron spectroscopy measurements. As a result of the IDA analysis, a value of (61 900±1500) b has been obtained for the 155Gd thermal capture cross-section at (Eth=25.3 meV).
Políticas indígenas en Chile (siglos xix y xx) de la asimilación al pluralismo -El Caso Mapuche-
Guillaume Boccara; Ingrid Seguel-Boccara
Introducción Antes de que la ley 19.253 de 1993 reconociera la existencia del pluralismo cultural en el territorio nacional y sentara las bases de la participación indígena en las políticas aplicadas por el Estado a las "etnias descendientes de las agrupaciones humanas precolombinas"(3), los pueblos autóctonos chilenos eran meros objetos del derecho. El papel pasivo que se les atribuía se remite fundamentalmente a la relación que el Estado chileno estableció desde su inicio con los pueblos in...
The economic, energy, and environmental impacts of the Energy-Related Inventions Program
International Nuclear Information System (INIS)
This report provides information on the economic, energy, and environmental impacts of inventions supported by the Energy-Related Inventions Program (ERIP) -- a program jointly operated by the US Department of Energy and the National Institute of Standards and Technology (NIST). It describes the results of the latest in a series of ERIP evaluation projects that have been completed since 1980. The period of interest is 1980 through 1992. The evaluation is based on data collected in 1993 through mail and telephone surveys of 253 program participants, and historical data collected during previous evaluations for an additional 189 participants
An experimental set-up for carbon isotopic analysis of atmospheric CO2 and an example of ecosystem response during solar eclipse 2010
Guha, Tania; Ghosh, Prosenjit
We present here, an experimental set-up developed for the first time in India for the determination of mixing ratio and carbon isotopic ratio of air-CO2. The set-up includes traps for collection and extraction of CO2 from air samples using cryogenic procedures, followed by the measurement of CO2 mixing ratio using an MKS Baratron gauge and analysis of isotopic ratios using the dual inlet peripheral of a high sensitivity isotope ratio mass spectrometer (IRMS) MAT 253. The internal reproducibil...
Vulnerability and the intention to anabolic steroids use among Iranian gym users: an application of the theory of planned behavior.
Allahverdipour, Hamid; Jalilian, Farzad; Shaghaghi, Abdolreza
This correlational study explored the psychological antecedents of 253 Iranian gym users' intentions to use the anabolic-androgenic steroids (AAS), based on the Theory of Planned Behavior (TPB). The three predictor variables of (1) attitude, (2) subjective norms, and (3) perceived behavioral control accounted for 63% of the variation in the outcome measure of the intention to use the AAS. There is some support to use the TPB to design and implement interventions to modify and/or improve individuals' beliefs that athletic goals are achievable without the use of the AAS.
Psychological Distress and Violence Towards Parents of Patients with Schizophrenia.
Kageyama, Masako; Solomon, Phyllis; Yokoyama, Keiko
The present study investigated the relationship between violence and psychological distress experienced by parents of patients with schizophrenia. Questionnaire data from 379 parents were analyzed. A total of 151 parents (39.8%) had not experienced violence in the past year, whereas 96 (25.3%) and 132 (34.8%) had experienced psychological violence only or physical violence, respectively. A total of 216 (57.0%) of parents reported being psychologically distressed. Multiple logistic regression revealed that the risk of psychological distress significantly increased with the experience of psychological and physical violence, lower household income, greater family stigma, and the increasing age of patients. PMID:27654247
Mapping of Hd6-f1 Gene on Rice Heading Date%水稻抽穗期基因 Hd6-f1的定位
Institute of Scientific and Technical Information of China (English)
周鹏飞; 柳絮; 张华; 宣宁; 李军; 杨永义; 李广贤; 姚方印; 刘开启
本试验以明恢63(供体)/早熟豫6(受体)的BC4 F2分离群体为材料,采用BSA ( Bulked segrega-tion analysis)法,对控制水稻抽穗期分离的基因进行SSR分子标记定位。 BC4 F2出现抽穗期分离,早抽穗植株为253株,晚抽穗植株为657株,χ2=3.66<P0.05=3.84,符合1∶3的孟德尔分离比,表明F2群体的抽穗期分离受一对等位基因控制,晚抽穗性状为显性。以明恢63×早熟豫6的BC4 F2分离群体的253株隐性单株为定位群体,将该抽穗基因(暂时命名为Hd6-f1)定位在水稻第6染色体分子标记RM19771与RM527之间,遗传距离分别为0.2 cM和2.9 cM,与RM19780共分离。%Using the BC4F2 segregation populations of Minghui 63(donor) and Zaoshuyu 6(receptor) as materials, the SSR markers were located for the gene on rice heading date by the bulked segregation analysis (BSA).The BC4F2 population had 253 early heading plants and 657 late heading plants( χ2 =3.66
Maternal Obesity: Consequences and Prevention Strategies
Emre Yanikkerem; Selviye Mutlu
Obesity is a medical condition in which excess body fat that it may have an adverse effect on health, leading to life expectancy and increased health problems. In keeping with the general international trend of rising prevalence of obesity, maternal obesity prevalence is rising. According to WHO, the prevalence of obesity in pregnancy ranges from 1.8 to 25.3%. Maternal obesity has been identified to be a risk factor for maternal and perinatal mortality. The aim of this article was reviewed in...
Efficacy of the Chicago Parent Program with Low-Income African American and Latino Parents of Young Children
Gross, Deborah; Garvey, Christine; Julion, Wrenetha; Fogg, Louis; Tucker, Sharon; Mokros, Hartmut
This study tested the efficacy of a 12-session parent training program, the Chicago Parent Program (CPP), which was developed in collaboration with African American and Latino parents. Using growth curve modeling, data were analyzed from 253 parents (58.9% African American, 32.8% Latino) of 2–4 year old children enrolled in 7 day care centers serving low-income families. Day care centers were matched and randomly assigned to intervention and waiting-list control conditions. At 1-year follow-u...
Effect of Condensed Tannins on Bacterial Diversity and Metabolic Activity in the Rat Gastrointestinal Tract
Smith, Alexandra H.; Mackie, Roderick I.
The effect of dietary condensed tannins (proanthocyanidins) on rat fecal bacterial populations was ascertained in order to determine whether the proportion on tannin-resistant bacteria increased and if there was a change in the predominant bacterial populations. After 3 weeks of tannin diets the proportion of tannin-resistant bacteria increased significantly (P < 0.05) from 0.3% ± 5.5% to 25.3% ± 8.3% with a 0.7% tannin diet and to 47.2% ± 5.1% with a 2% tannin diet. The proportion of tannin-...
Comorbid psychiatric diagnoses among individuals presenting to an addiction treatment program for alcohol dependence.
LENUS (Irish Health Repository)
Lyne, John Paul
A retrospective patient record review was conducted to examine comorbid psychiatric diagnoses, and comorbid substance use, among 465 patients below 45 years of age, presenting to a national alcohol addiction treatment unit in Dublin, between 1995 and 2006. Rates were high for depressive disorder (25.3%) particularly among females (35.4%). Lifetime reported use of substances other than alcohol was 39.2%, and further analysis showed significantly higher rates of deliberate self-harm among this group. Lifetime reported use of ecstasy was also significantly associated with depression in this alcohol-dependent population using logistic regression analysis. Implications and limitations of the findings are discussed.
Assessment of Calculation Procedures for Piles in Clay Based on Static Loading Tests
DEFF Research Database (Denmark)
Augustesen, Anders; Andersen, Lars
College in London. The calculation procedures are assessed based on an established database of static loading tests. To make a consistent evaluation of the design methods, corrections related to undrained shear strength and time between pile driving and testing have been employed. The study indicates...... that the interpretation of the field tests is of paramount importance, both with regard to the soil profile and the loading conditions. Based on analyses of 253 static pile loading tests distributed on 111 sites, API-RP2A provides the better description of the data. However, it should be emphasised that some input...
Structure and Property of Bamboo Fiber
Institute of Scientific and Technical Information of China (English)
The chemical composition, fiber characteristics, crystalline structure, mechanical properties and thermal behavior of the five species of bamboo (Phyllostachys edulis cv.Pachyloe, Bambusa tootisk, Arundinaia amabilis, B.vulgaris cv. Vittata, and Dendrocalamus affinis) were studied with IR, X-ray, DSC and chemical analyses. The results indicated that the benzene-ethanol extractive content of bamboo was higher than that of wood, the content of lignin and the content of pentosan were 19.1% - 25.3% and 14.9% - ...
Expression, purification, crystallization and preliminary X-ray analysis of an NAD-dependent glyceraldehyde-3-phosphate dehydrogenase from Helicobacter pylori
International Nuclear Information System (INIS)
Glyceraldehyde-3-phosphate dehydrogenase B from H. pylori has been cloned, expressed, purified and crystallized in the presence of NAD. Crystals of GAPDHB diffracted to 2.8 Å resolution and belonged to space group P6522, with unit-cell parameters a = b = 166.1, c = 253.1 Å. Helicobacter pylori is a dangerous human pathogen that resides in the upper gastrointestinal tract. Little is known about its metabolism and with the onset of antibiotic resistance new treatments are required. In this study, the expression, purification, crystallization and preliminary X-ray diffraction of an NAD-dependent glyceraldehyde-3-phosphate dehydrogenase from H. pylori are reported
Evaluación energética de los refrigerantes R1234yf y R152a como alternativa al R134a en sistemas de refrigeración
Navarro Esbrí, Joaquín; Mota Babiloni, Adrian; Peris Pérez, Bernardo; Molés Ribera, Francisco; Mendoza Miranda, Juan Manuel; Belman Flores, Juan Manuel; Rubio Arana, Jose Cuauhtémoc
[EN] This paper presents a theoretical performance of R1234yf and R152a as possible replacements of R134a in refrigeration systems. The refrigeration system performance using R134a, R1234yf and R152a was carried out for single stage refrigeration system for different evaporating condition ranging from 253 to 283 K and for condensing temperatures of 313 K, 323 K and 333 K holding 5 K as superheating degree and subcooling degree. Refrigerant performance is evaluated using COP, cooli...
Measurements of energetic particle radiation in transit to Mars on the Mars Science Laboratory.
Zeitlin, C; Hassler, D M; Cucinotta, F A; Ehresmann, B; Wimmer-Schweingruber, R F; Brinza, D E; Kang, S; Weigle, G; Böttcher, S; Böhm, E; Burmeister, S; Guo, J; Köhler, J; Martin, C; Posner, A; Rafkin, S; Reitz, G
The Mars Science Laboratory spacecraft, containing the Curiosity rover, was launched to Mars on 26 November 2011, and for most of the 253-day, 560-million-kilometer cruise to Mars, the Radiation Assessment Detector made detailed measurements of the energetic particle radiation environment inside the spacecraft. These data provide insights into the radiation hazards that would be associated with a human mission to Mars. We report measurements of the radiation dose, dose equivalent, and linear energy transfer spectra. The dose equivalent for even the shortest round-trip with current propulsion systems and comparable shielding is found to be 0.66 ± 0.12 sievert.
[Importance of cooling after death for restoration of metabolism during resuscitation].
Pogosova, A V; Petukhova, L M; Nikulin, V I; Konikova, A S
Incorporation of labelled metabolites into proteins, RNA and DNA was completely inhibited in rabbit tissues under conditions of prolonged hypothermia (10 degrees). The incorporation of labelled metabolites into all the biopolymers studied was restored after subsequent warming up to 38 degrees. Within 60-90 min after death of the animals due to acute anoxia, the labelled metabolites did not incorporate into protein, RNA and DNA. Artificial postmortal hypothermia (20 degrees) increased (by about 2.5-3-fold) the period of viability, during which reanimation is possible. The hypothermia enables subsequent restoration of the anabolic processes from the zero level. PMID:734984