text:
Relevant offers
Beauty News
Rihanna has hinted that she could be the new face of Chanel.
The Barbadian singer may have accidentally revealed the "top secret" fashion news after she posted a picture of herself from the set of a new photoshoot on her Twitter account.
In the image Rihanna is seen wearing nothing more than a white towel with the notable addition of some Chanel necklaces hanging from her neck.
"And that's a #wrap on my shoot for my new #topsecret add campaign!!! #2013 #phuckyobasic, (sic)" Rihanna captioned the photo.
In the image, the star also sports bright red lipstick, with red nail varnish painted on her fingers.
The notable inclusion of Chanel branded accessories and their trademark rouge colour suggests Rihanna was shooting images for the French luxury label.
Previous 'faces' for the iconic brand have included Kate Moss, Catherine Deneuve, Keira Knightley and Brad Pitt.
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The week in celebrity Instagrams
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This week we tried: A lash lift
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Q&A: Is it OK to use olive oil as your default for cooking?
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Rolls-Royce unveils bespoke 'Sweptail' - is it the world's most expensive new car?
7 subtle signs of high stress you might not know about
Why we need a new word for spinsters like me
The pretty palm tree that can bring a world of pain
Aussie mother Adele Barbaro to livestream childbirth
A wildly popular logic puzzle is driving people to distraction
What's your fave grooming option?


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subset: commoncrawl


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What airfield can I expect?
Gongue is a laterite runway located in the Forêt des Abeilles ("bees forest", but these don't sting, btw) about 40NM northwest of Koulamoutou. The runway was built in a gully between two hills, which was partially filled with earth. Runway 18 is upslope, so it is used for landing. Beware of the hill covered with massive trees after the runway: any missed approach decision must be made early. Runway 36 is used for takeoff. A timber camp is located less than a mile northwest of the strip. Runway surface is hard and quite smooth, but is easily furrowed by rains. Check for mud as well, as it can get pretty sticky after heavy rains. The surrounding terrain is made up of hills, beware of not getting in low-level IMC while trying to get in.
Airplanes normally park at the end of runway 18. No tiedowns, no flight plan, no fees. The runway is the property of Leroy Gabon, a timber company. Authorization to operate on the airfield should be sought from their offices in Libreville at +(241) 74 32 51.
Where am I?
In the middle of 6,000 km² of forest, exploited from the nearby timber camp.
Where do I sleep?
The only place to sleep is the nearby Leroy Gabon camp. Such accomodation must be arranged beforehand with the main office in Libreville.
Where do I eat?
Meals at the camp would have to be arranged with the camp operator.
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The "Semi Finals" episode starts with the top 4 home cooks walking into the MasterChef Kitchen to find out they will have to make a dish with a very special ingredient: Chocolate! Tons of Chocolate Chips fall on the kids' heads. Shayne tries some and tells Gordon they taste good! J The judges treat the home cooks to a perfectly made Chocolate Molten Lava Cake with a berry coulis. Their challenge will be to replicate this dessert. The winner of this challenge will get a big advantage going forward.
Adam and Jasmine are very comfortable baking. Adam loves science and baking is science. He says, "Making a Molten Lava Cake is like a science experiment. You have to have the right proportions. You have to have the right temp on the oven. And you have to have it cooked for the proper amount of time. And if one of those things goes wrong, you're going to blow up your lab!"Justise and Shayne admit it is not their favorite kind of cooking. Time gets the better of Justise and she does not get her cake out of the ramekin. Shayne has trouble pulling the plate together and gets it down to the front just in time!
35 minutes is up! Time to taste them!
Shayne's lava cake is stunning and tastes delicious. Unfortunately he did not get the fruit on his plate.
Jasmine's lava cake plate is the most beautiful of the four. Christina says, "It's gooey. It's perfectly molten lava."
Adam's lava cake broke and is a bit under cooked. Gordon says he should have turned up the heat at the end to help it along. His fruit and coulis are great though.
Justise's lava cake didn't work out and fell apart. Flavor wise it is delicious, but this challenge got to her. Christina says, "You know how to fight, and you know how to recover."
Jasmine has the best lava cake dessert and wins a big advantage. She can assign each home cook their protein for the elimination challenge; Pork, Lamb, Beef or Goat. Jasmine chooses Lamb for herself, gives Beef to Adam, Pork to Shayne and Goat to Justise.
During the cook time Adam knows how hard it is to elevate the beef and that he will have to take some risks by picking daring cut of beef and sides and do something special with the sauce.
Shayne is confident. He says the pork chop reminds him of a relaxing Sunday dinner at home, but tonight he will be stepping it up. The judges are confused when Shayne cooks two chops but uses a thermometer to check temp on the one he is plating instead of cutting into the spare chop to see if it's done. Will his chop be undercooked?
Jasmine is making something out of her comfort zone to show the judges that she can cook more than her signature Jamaican flare. When Gordon asks her why she doesn't go easier on herself, she answers, "Well, because, if you want to go easy, there's really no reason for you to be here in this competition."
Justise is taking a big risk cooking her goat leg in a pressure cooker because she is basically cooking blind. She is counting on it to give the goat lots of juices and flavor. Gordon is not sure she will have enough time for a proper curry dish.
Time is up.
Jasmine made Mediterranean Lamb with Herb Couscous, Olive Puree and Pickled Bell Peppers. The rack of lamb has a nice even sear and is cooked perfectly. The olive and fennel flavors are great compliments to her dish. Christina thinks the peppers should have been sliced thinner and Gordon thinks the couscous is an odd choice with rack of lamb. But overall, she nailed it. Gordon says, "It's definitely one of the best cooked proteins, ever, in this competition. Well done."
Adam made a Grilled Rib Cap with Mushroom Sauce, Endive Two Ways, Fennel-Endive Puree and Asparagus. This cut was a bold choice, but it needed to be basted, not baked, to render the fat down. And his veggies are under seasoned, but his mushroom is delicious. Gordon says, "It breaks my heart to say this, but this is one of your weakest performances."
Justise made Vadouvan Goat Curry with Cilantro Scented Rice and Crispy Shallots. It is amazing. The meat is incredible, fragrant, spicy, sweet and sour. She nailed it! Christina says, "You took something that is not normally elevated and you brought it to another level."
Shayne made Grilled Pork Chop with Maple Soy Glaze, Chipotle Sweet Potato Mash and Apple Slaw. The pork chop is cooked to perfection. Gordon says, "It's glistening, it's juicy, I mean seriously that's fit to go into any top restaurant in New York, let alone London or Paris." It is seasoned and glazed so well, but the sides are a bit messy. The hero is the protein and he nailed it.
In the end, the first cook in the Finale based on these dishes is Justise! The other home cook will be … Jasmine! That means Shayne and Adam are going home. 😦 This is a hard one, all four cooks are so amazing.
Christina says, "Adam, your ability, your desire to want to take risks and challenge the rules is really impressive. I have no doubt that your dream for your test kitchen is going to come true." And Gordon says, "Promise you won't stop."Gordon says, "Shayne, not only are you one of the most lovable characters, but you and I've got a big connect, because you put your heart and soul into everything you do. This is why we started this competition, based on boys like you. Do you know that? Good man." And Christina says, "You are an outstanding human being."
Both kids get hugs and cheers when they are walking out and Shayne says, "Come on Adam, we're fine." 🙂
Final words from Adam: I'm sad to be leaving the MasterChef Kitchen. But this is definitely going to be a time of my life that I will never forget. I've grown so much since I've first came here. I've gone from being twelve year old science guy from Sacramento, California, to being a bona fide chef. I'm really proud of myself, I've done so much more than I ever thought I could. I've gotten to cook with some of the greatest chefs in the world. Now I have friends all over the country.
Final words from Shayne: I've put my heart and soul into everything in this competition. I represented Texas as best as I can. I mean, who thought a little kid from Texas would make the best vegan burger? Even though we had our bumps in the road, I've had so much fun, win or lose. All in all, how many kids can say they got into the semi-finals of the biggest cooking competition in the world? Not many. God had a plan no matter what happen, so I really think that if it was my time to go… it's my time to go.
I really liked this episode because I was happy to see Shayne and Adam cook for one last time. I was also happy for Justise and Jasmine when they got in the finale. I think all the kids showed a lot of heart and support for each other.
And finally, to Shayne: (I hope you are reading) I just want to say thank you so, so, so much for reading my blog and saying such amazing things about it. When you gave me a shoutout on your Facebook page it made me so happy. You are a great friend. I have been rooting for you since day one. I really wanted you to win the whole thing and I was sad when you left. However, no matter what, you are a winner in my heart based on your amazing attitude. You were nice to all the kids on the show. You always had such a great time. I wish you the best of luck. I know you will get your Food Truck one day and go on to do amazing things.


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If you are looking to save some money on your move, a do-it-yourself service may be the right choice. One of the challenges of the do-it-yourself move is loading your possessions in the moving van. Movers Corp prepared tips on how efficiently to load a moving truck.
Loading a Moving Truck
When planning a local move, it is important to be prepared before your hired company arrives. Movers Corp provides you with all the moving suggestions and tips for a carefree relocation.
Moving Timeline
How to avoid injuries to yourself and others while moving yourself. Guide to moving large pieces of furniture the safe way.
How to Safely Move Furniture
Here are some moving tips in pictures. An interesting guide on how to move yourself and stay in control.
DIY Moving Tips
Do you need assistance on how to pack and transport heavy items? Find out everything about packing and shipping large and heavy items.
How to Pack Heavy Items
Moving companies in Bloomdale, Ohio - Local Movers


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Washington D.C., Jan 12, 2017 / 03:18 am (CNA/EWTN News).- Global persecution of Christians has risen for the fourth year in a row and is on a "rapid rise" in Asia, the advocacy group Open Doors UK warned on Wednesday in its annual report on Christian persecution.
"Religious nationalism is sweeping the globe according to figures released today as part of the Open Doors 2017 World Watch List," said Lisa Pearce, CEO of Open Doors UK & Ireland.
"Persecution levels have been rising rapidly across Asia and the Indian subcontinent, driven by extreme religious nationalism which is often tacitly condoned, and sometimes actively encouraged, by local and national governments."
On Wednesday, the group Open Doors released its annual World Watch List on the state of global persecution of Christians. The list ranks the countries where the worst persecutions of Christians are taking place based on information gathered from field workers and "independent experts."
Open Doors was founded in 1955 by a Dutchman named Brother Andrew who smuggled Bibles into Communist Eastern Europe. Since then, the organization has grown to aid Christians in 50 countries by sending them Bibles and other needed materials, and speaking out for their well-being.
Overall persecution of Christians has risen from last year, Open Doors UK noted, stating that "Christians are being killed for their faith in more countries than before."
"Christians living in these countries need the support of their family, the body of Christ, to help them stand firm in their faith," they stated.
Pakistan had the most fatal attacks against Christians, "even more than Northern Nigeria," the report noted. Mexico also saw a violent spike in the killings of 23 Christian leaders in 2016, including the abductions of several priests. The country has seen 15 priests killed since the election of current President Enrique Pena Nieto in 2012.
For the 16th consecutive year, Communist dictatorship North Korea was determined to be the "worst place on earth for Christians," Open Doors UK said. There are 300,000 Christians amidst the population of 25.4 million.
Christians there suffer from a totalitarian police state that closely monitors their actions and requires them to worship the ruling family, the report said. They must pray privately. Those discovered by the state to be Christian may end up in harsh labor camps where an estimated 50-75,000 Christians currently suffer.
"Every day was as if God was pouring out all ten plagues on us simultaneously," revealed one Christian women who was held captive in the camps but escaped. "That's how hard it was. But God also comforted me and brought a secret fellowship into existence. Every Sunday we would gather in the toilets and pray."
All top 10 countries with the worst persecution of Christians are in Asia and Africa. Somalia ranks second on the list, followed by Afghanistan, Pakistan, the Sudan, Syria, Iraq, Iran, Yemen, and Eritrea.
Somalia, ranked the second-worst country for persecution of Christians, "has persecution levels nearly as high as in North Korea," Open Doors UK noted.
"Islam is Somalia's state religion and all Christians come from a Muslim background," they explained, meaning that for converts to Christianity, if their conversion is discovered, it can mean persecution and even a "rushed beheading."
"If a Christian is discovered in Somalia, they are unlikely to live to see another day," Lisa Pearce stated. There are only hundreds of Christians in the country with a population of over 11 million.
At least 12 Christian converts were killed in Somalia in 2016, the report said. The country is ruled by a "tribal system" and is "basically lawless," which means that entities like the militant group al-Shabaab can "persecute Christians with impunity."
Afghanistan is number three on the list, another tribal country where being a Christian is illegal. The Islamic republic of Pakistan is fourth, where more Christians were recorded as killed for their faith in 2016 than any other country. There are almost 4 million Christians there amidst the population of over 196 million.
An estimated 700 Christian women and girls were abducted in 2016, many of them raped and forced to marry Muslim men. The country's strict blasphemy laws – which carry a death sentence – enable mob violence against Christians and accusations of blasphemy committed with impunity.
Persecution of Christians has had a disturbing increase in Asia, Open Doors noted, including in the world's second-most populated country of India where there are 15 attacks against Christians every week, and probably more than that number since some attacks are not reported by fearful victims.
There were "at least ten" abductions of Christians there in 2016, ten rapes of Christian women, and over 800 physical attacks on Christians, the report said. Laos, Bangladesh, and Vietnam have also seen greater persecution of Christians by religious nationalists.
In the Middle East, Christians have been "caught in the crossfire" of wars in Yemen, Syria, and Iraq. "The Saudi-backed civil war in Yemen has reduced the country to a waste land, with many Christians caught in the crossfire, such as the 16 people killed in an attack on a Christian care home for the elderly and disabled," the report said.
Other problems of persecution include Islamic extremism in sub-Saharan Africa, and attempts to destroy the homes of Christians who have been driven away by violence, in the hopes that they permanently resettle elsewhere.
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customer service phone i like talking to people not email
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Best price I have found.
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Our Trip is in May. Your process was wonderfil and allowed us to make our choice of time and date we wanted to travel.\nThank You.
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Statistics and meaning of name Marlek
Usage: 66% firstname, 34% surname.
Marlek first name was found 6 times in 1 different countries. (USA)
Surname Marlek is used at least 3 times in at least 1 countries. (USA)
Marlek reversed is Kelram
Name contains 6 letters - 33.33% vowels and 66.67% consonants.
Anagrams: Kalerm Rmaelk Mraekl Armekl
Misspells: Morlek Mallek Marrlek Marleka Mralek Marlke Marelk
Rhymes: garlic folic anarchic gnostic karmic
Meaning of this name is unknown.
Marlek says: Gostaria de saber tudo sobre meu nome
This page has been visited from the following countries:
Marlek.com - UNKNOWN Marlek.net - FREE Marlek.co.uk - FREE Marlek.de - REGISTERED
Faces of people named Marlek
Recent searches: Planalp Vatle Kielczykowski Capperella Sogliuzzo Veratti Navodaru Darabut Hokyan Bogopolsky
Top searches: Poyiadjis Tante Mueller Kahoot Fischer Pahlke Amparine Saucha Bosta Drzymalla
Random names: Eksteen Lillefjell Tryggestad Ternig Ajini Uvalles Louahed Turias Rodrogues Yazdanmehr
Do you know more about the meaning
or about the origins of this name?
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or about the origins of this name?
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Visit Worcestershire
Welcome to the official Visit Worcestershire website - full of tourist information for Worcestershire for all the things you need to know to help plan day trips, short breaks or family holidays in Worcestershire - a beautiful West Midlands county.
You can explore the vast amount of attractions and things to see and do, enjoy the great outdoors including the beautiful countryside and the many waterways, discover more about the history and heritage of the area including; Worcester's part in the English Civil War, an array of historic houses and a steam railway. There is also plenty to do for the whole family and unique shopping experiences. The county is also renowned for its sports including premiership rugby, first division cricket, basketball and horse-racing fixtures.
Accommodation providers offer a mixture of facilities whatever your budget for holidays in Worcestershire, including country house hotels, B&B's, self catering, camping and caravanning sites.
Worcestershire is famous for its local Food and Drink Produce and it's not just the sauce. Pubs, Restaurants and Cafes across the county serve local food and drink produce ensuring an authentic Worcestershire experience.
You can also search for many Festivals and Events happening throughout the year.
Let Worcestershire Tourist Information help you make your holiday in Worcestershire perfect!
Exploring Worcestershire
Tue 23 May 2017
Learn to draw your own cartoons with artist Lee Bradley.
Wed 24 May 2017
General Market in Angel place on Monday, Wednesday and Saturday's with a fabulous mix of goods as well as fresh produce and street food.
Thu 25 May 2017
In this lecture David Starkey draws on his unique knowledge of Henry's reign on the one hand, and his insights as a leading commentator on modern politics on the other, to illuminate both the Tudor age and our own.
Thu 25 May 2017
A glorious theatre show, widely regarded as the best of its kind currently touring the U.K. It brings together the very best authentic burlesque performers who combine for a superb evening of tassels, tease, comedy, music and cabaret. 16+
Sat 27 May - Sun 4 Jun 2017
Nine days of walks in Elgar country, ranging from gentle strolls to long, challenging walks, covering a rich variety of themes. Details available on the website, in Tourist Information Centres & other locations. www.malvernwalking.uk
Sat 27 - Mon 29 May 2017
Join The Commandery, Worcester for their traditional spring-time celebration of the restoration of the monarchy in 1666.
Sat 27 May - Sun 4 Jun 2017
Look out for the eighteenth century inspired pavilion in the gardens at Berrington, designed and created by internationally renowned artists Heather and Ivan Morison.
Mortimer Country
Sat 27 May - Sun 4 Jun 2017
Step into the magical world of C. S. Lewis, brought to life in the grounds of Croft, on our family trail this half-term.
Sun 28 - Mon 29 May 2017
Elizabethan Living History. Discover how the Elizabethans worked, fought and played.
Wed 31 May 2017
An ideal opportunity for aspiring young potters to work with professional, ceramic artists. Experience 'hands on' real clay with an exciting variety of making techniques.
Mon 5 - Fri 9 Jun 2017
International Wheelchair Basketball Tournament
Sat 17 Jun 2017
A food & drink festival featuring around 100 local producers and chef demonstrations held in the beautiful surroundings of the Lido Park in Droitwich Spa. Star Chef will be TV Chef Brian Turner.
Sun 18 Jun 2017
Join us this Father's Day and treat Dad (or yourself!) to a Free Beer* in our Garden Tea Room
Upton upon Severn
Thu 22 - Sun 25 Jun 2017
Celebrating the glorious sounds of Jazz.
Fri 30 Jun - Sun 9 Jul 2017
A 10 day national and international poetry festival - readings, open-mics, Slams, street entertainment, family activities, national competition winners.
Sun 2 Jul 2017
Spetchley is proud to be one of the original Gardens to open for charity under the National Gardens Scheme, 2017 marks the 82nd year of participation. Normal admission applies.
Local Tourism News
19 May 2017
A National Trust team has received a sought after accolade at the annual Museums and Heritage Awards which recognizes the innovators and leaders in the world of heritage visitor attractions.
17 May 2017
The Love Your Local Market campaign returns to Worcester.
The Love Your Local Market Campaign was started in 2012 following recommendations made in the Mary Portas Review. The recommendations called for a National Market Day, which soon developed into Love Your Local Market Fortnight, that now takes place annually in May.
11 May 2017
A selection of Roman coins from the Bredon Hoard is being displayed at the Broadway Museum and Art Gallery until the end of May so don't forget to bring family and friends to see the collection while it is here.
4 May 2017
From May 2017, the Broadway Museum & Art Gallery will host an exhibition of embroidered clothing from the Ashmolean Museum revealing many hidden gems from its collections.
Featured Accommodation
Treherne House
Bed & Breakfast with 4 rooms, £78-£135 prpnb
Brockencote Hall
Hotel with 21 rooms, £120-£190 prpnb
The Old Town Hall
Bed & Breakfast with 3 rooms, £40-£65 prpnb
Osborne House
Guest Accommodation with 4 rooms, £35-£80 prpnb
Roundstone View Holiday Let
Chalet with 1 unit, £560-£840 pupw sleeps 1-6
Fern Cottage
Self-catering with 1 unit, £0-£475 pupw sleeps 1-4
Bank House
Bed & Breakfast with 4 rooms, £37-£40 pppnb, £62-£65 prpnb
The Dell House
Self-catering with 3 units, £350-£740 pupw sleeps 1-6
The Durrance
Self-catering with 2 units, £250-£420 pupw sleeps 3-4
Canvas and Clover
Glamping with 10 units, £75-£95 pupn sleeps 1-5
Green Farm
Farmhouse with 3 rooms, £75 prpnb
The Talbot Inn
Bed & Breakfast with 14 rooms, £90-£160 pppnb
Fern View
Self-catering with 1 unit, £450-£650 pupw sleeps 1-6
Hope End Holidays
Self-catering with 1 unit, £180 pupn sleeps 2-5
The Pembridge
Guest House with 8 rooms, £53-£87 prpnb
Bank House Hotel, Spa and Golf Club
Hotel with 68 rooms
University of Worcester
Self-catering with 1239 units, £0-£43 pupw sleeps 5
Henwick House Bed & Breakfast
Bed & Breakfast with 7 rooms, £0-£88 pppn, £35-£79 prpnb
Phepson Farm Cottages
Self-catering with 4 units, £273-£600 pupw sleeps 2-6
Bewdley Hill House Bed & Breakfast
Bed & Breakfast with 6 rooms, £60-£65 prpnb
Hop Pickers' House at Brook Farm
Self-catering with 2 units, £480 pupw sleeps 2
The Fleece Inn (National Trust)
Inn with 1 room, £98 prpnb
The Barn, Beechcroft
Self-catering with 1 unit, £350-£650 pupw sleeps 5-6
Hillside Cottage
Self-catering with 1 unit, £225-£395 pupw sleeps 1-4
Hanbury Hall (National Trust)
Self-catering with 3 units, £237-£740 pupw sleeps 2-3
Brides Manor at Stanbrook Abbey Hotel
Self-catering with 1 unit, £700 pupn sleeps 10
White House Cottages
Self-catering with 5 units, £200-£510 pupw sleeps 1-5
Look Out Lodge
Self-catering with 1 unit, £600-£1000 pupw sleeps 2-6
The Firs
Self-catering with 1 unit, £300-£350 pupw sleeps 1-2
Colwall Park Hotel
Hotel with 19 rooms, £70-£160 prpnb
Hop Pickers Rural Retreats
Self-catering with 3 units, £525-£1025 pupw sleeps 1-5
Huntlands Farm Bed & Breakfast
Bed & Breakfast with 5 rooms, £70-£75 pppnb, £70-£105 prpnb
Holly Lodge
Self-catering with 1 unit, £350-£600 pupw sleeps 2-8
Rochford Park Cottages
Self-catering with 3 units, £193-£740 pupw sleeps 2-8
The Cardinals Hat
Bed & Breakfast with 4 rooms, £50-£120 prpn, £65-£190 prpnb
Eckington Manor
Guest Accommodation with 13 rooms, £75-£225 prpn
Crown and Sandys
Inn with 6 rooms, £80 prpnb
The New Cottage
Self-catering with 1 unit, £330 pupw sleeps 1-4
Evesham Lodge B&B
Bed & Breakfast with 2 rooms, £60-£85 prpnb
Eastnor Deer Park
Touring & Camping Park with 50 pitches, £7-£9 ptpn


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This note was uploaded on 05/09/2011 for the course HIST 2057 taught by Professor Rand during the Spring '08 term at LSU.
- Spring '08
- Rand
- George Washington, John Adams, The American, The Federalist Papers, Federal government of the United States, John Quincy Adams
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Music Gear News
Paul Weller reveals he improvised lyrics for new album
Electric guitar player Paul Weller has revealed he adopted a new way of working for his latest album improvising the lyrics over the top of backing tracks when he was in the studio.
Speaking to BBC 6 Music, the former frontman of The Jam revealed that it was the first time he had gone about recording music in such a way, but he was pleased to try something new.
"I didn't really sit down with a guitar and try to work them out," he explained, adding that he would instead spend a couple of weeks listening to each backing track.
"It's nice after all these years to think there's still a method of working which you haven't done before."
The results can be heard by fans very soon as his new record, Wake Up The Nation, is set to be released next Monday (April 19th 2010).
Weller is set to play an arena tour in support of the album later this year, with dates planned in cities including Cardiff, Glasgow and London.Posted on 14 Apr 2010 15:58 to category : Band / Celebrity News
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Through a collaboration with Martin, Sheeran's latest signature model features artwork from his latest album '÷' and has been built to his exact specifications.
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Founding guitarist of legendary LA band Y and T Joey Alves passes away due to complications relating to Ulcerative Colitis. Documentary on soon to follow.
Destroyer Cola is to be the latest release in rock veterans Kiss' long line of merchandise currently available to the general public for purchase
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Charming hotel in historic town. Host was most accommodating in spite of no English on his part and no Spanish on ours. Room was clean and comfortable. It was hard to find, we just stumbled upon it, but it was worth it
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Published on
Find here a collection of projects that give a quick look into the tools of my trade. As part of the engineering school, I had access to a full array of manufacturing tools and methods.
These helped me prototype both rough and final versions of the projects I worked on while studying Product Design at Stanford University.


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Tutustu kiinnostaviin ideoihin!
Tutustu aiheeseen liittyviin aiheisiin
yeaa buddyy
Yay.. this has restored what little hope I have left in humanity!
Wifey in Training
Hosea 6:3
"When God know you're ready for the responsibility of commitment, He'll reveal the right person under the right circumstances. Wait patiently. Don't waste your time searching and wishing. Grow and be ready, you'll see God will give you a love story far better than you could ever dream of."
Jesus is all of the above!
Amen, in Jesus name I accept my blessings of desires in abundance of immeasurable proportion, I accept salvation by confessing with my mouth that you my Lord Jesus, King of kings are my Lord and Savior, my God, because of you father everything I speak comes to fruition commanded by the Holy Ghost, through the everlasting love of Jesus Christ, embraced in Gods mercy and grace. Amen... Lisa Christiansen, child of the one true king ΙΧΘΥΣ
I Hope You Dance :)


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Written on: 20/10/2013
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Asmussen E. Apparent Efficiency and Storage of Elastic Energy in skeletal Muscles in Man. Acta Physiol Scand, 1974; 91: 385-392 [Crossref]
Asmussen E., Bonde-Petersen F. Storage of Elastic Energy in Skeletal Muscles in Man. Acta Physiol Scand, 1974; 92: 537-545 [Crossref]
Aziz AR, Mukherjee S, Chia MY, Teh KC. Validity of the Running Repeated Sprint Ability Test Among Playing Positions and Level of Competitiveness in Trained Soccer Players. Int J Sports Med, 2008; 29: 833-838 [PubMed] [Crossref] [Web of Science]
Bland JM, Altman DG. Statistical Method for Assessing Agreement Between Two Methods of Clinical Measurement. Lancet, 1986; 8: 307-310 [Crossref]
Cavagna GA. Elastic Bounce at the Body. J Appl Physiol, 1970; 29: 279-292 [PubMed]
Cavagna GA, Dusman B, Margaria R. Positive Work Done by a Previously Stretched Muscle. J Appl Physiol, 1968; 24: 21-32 [PubMed]
Cavagna GA, Saiberne FP, Margaria R. Effect of Negative Work on the Amount of Positive Work Performed by an Isolated Muscle. J Physiol-London, 1965; 20: 157-158
Ferreira JC, Carvalho RGS, Szmuchrowski LA. Validity and Reliability of a Contact Mat for Height Vertical Jump Measurement. Brazilian Journal of Biomecanics, 2008; 9 (2): 39-45
Ford LE, Huxvey AF, Simmons RM. Tenses Responses to Sudden Length in Stimulated Frog Muscles Fibers Near Slack Length. J Physiol-London, 1976; 269: 441-515
Gissis I, Papadopoulos C, Kalapotharakos VI, Sotiropoulos A, Komsis G, Manolopoulos E. Strength and Speed Characteristics of Elite, Subelite and Recreational Young Soccer Players. Res Sport Med, 2006; 14: 205-214 [Crossref]
Harman EA, Rosenstein MT, Frykmam PN, Rosenstein RM, Kraemer WJ. Estimation of Human Power Output from Vertical Jump. J Appl Sport Sci Res, 1991; 5: 116-120
Malliou P, Ispirlidis I, Beneka A, Taxildaris K, Godolias G. Vertical Jump and Knee Extensors Isokinetic Performance in Professional Soccer Players Related to the Phase of Training Period. Isokinet Exerc Sci, 2003; 11: 165-169
Melvill JG, Watt DG. Muscular Control of Landing from Unexpected Falls in Man. J Physiol-London, 1971; 219: 729-737
Newton RU, Kraemer WJ. Developing explosive muscular power: implications for a mixed methods training strategy. Strength Cond, 1994; 10: 20-31 [Crossref]
Peter JP. Reliability: A Review of Psychometric Basics and Recent Marketing Practices. J Marketing Res, 1979; 16: 6-17 [Crossref]
Skurvydas A, Jascanin J, Eider J. Low Frequency Fatigue of Quadriceps Muscle During Eccentric Exercise. J Hum Kinet, 1999; 1: 69-75
Socha T, Skowronek T, Socha S. Somatic and Functional Variables Determining Game Efficiency of Ice Hockey Players. J Hum Kinet, 2006; 15: 61-74
Stone MH, O'Bryant HS, McCoy L, Goglianese R, Lehmkuhl M, Schilling B. Power and Maximum Strength Relationships During Performance of Dynamic and Static Weighted Jumps. J Strength Cond Res, 2003; 17: 140-147 [PubMed]
Wisloff U, Castagna C, Helgerud J, Jones R, Hoff J. Strong Correlation of Maximal Squat Strength With Sprint Performance and Vertical Jump Height in Elite Soccer Players. Brit J Sport Med, 2004; 38: 285-288 [Crossref]
About the article
Published Online: 2012-07-04
Published in Print: 2012-06-01
Citation Information: Journal of Human Kinetics, ISSN (Online) 1899-7562, ISSN (Print) 1640-5544, DOI: https://doi.org/10.2478/v10078-012-0050-4. Export Citation
This content is open access.


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Join the '4-Way Menthol' group to help and get support from people like you.
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The price of oil has declined a lot since the summer of 2014. The West Texas Intermediate (WTI) in Cushing, Oklahoma has declined from a high of $107.52/barrel in June 2014 to a low of $45.25/barrel in August 2015. This severe decline in prices has reduced the earnings power of many energy dividend growth stocks, which are engaged in exploration and production.
The question on everyone's mind is whether these dividends are safe. Only after we answer this question, can we determine whether it makes sense to purchase those shares for income in a dividend growth portfolio.
Back in late 2014, I discussed whether the oil price decline was the opportunity of a lifetime. I talked about three companies I had my eye on. Initially, I discussed how I wanted to slowly build my positions every month. I even made a purchase of ConocoPhillips in early 2015, followed by a small purchase of Exxon Mobil (XOM) a few later. As I was buying Exxon Mobil, I had a change of heart after realizing that the oil price shock had drastically reduced energy companies' earnings a few weeks later. Therefore, the drop in share prices was much lower than the decline in earnings power, which made those shares overvalued. As a result, I changed course and only recently bought shares in Exxon Mobil.
Continue Reading on Seeking Alpha
Full Disclosure: Long XOM, CVX, COP, KMI, WMB, OKE,
Relevant Articles:
- The Energy Company I want to buy
- Are Energy Stock Values Today a Once in a Lifetime Opportunity?
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Monday, August 10, 2015
Are these oil dividends safe?
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Dr. Amy Schefler MD Patient Reviews
- Ophthalmology Houston, TX
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Very competent and professional. Really great doctor.
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The Ballhooter Spring Break Festival will be taking place on March 10 thru 12 2017. The event will feature music, games, and other activities. Hosted by Snowshoe Mountain, the festival will also have life-size versions of some of your favorite childhood
Are you wanting to get out of the house this winter and have some fun? Willing to try something new or have a fun, family day? Or are you looking to just hang out with friends and enjoy the winter
West Virginia was named the Mountain State for good reason. People from all over follow West Virginia's fabled country roads to visit some of the best ski resorts in the nation. Located entirely in the Appalachian Mountain range, West
Our couples ski trip to West Virginia landed us in the perfect skier's paradise. Snowshoe Mountain is an amazing destination with skiing and snowboarding options for every level of expertise. I love skiing, but I've never been exceptional at it,
If you are looking for a place to vacation that offers beautiful scenery and fun activities for children and adults alike, look no further than Pocahontas County WV. There are a wide range of things to see and do during
Snowshoe, West Virginia was the location for the fourth annual Ballhooter Spring Break Festival from March 11-13, with performances by some big name entertainment. Bud Light sponsored this year's festival, which featured Brooklyn recording artists, American Authors, with their recent
Watoga State Park, located near to Snowshoe WV, is 10,000 acres worth of outdoorsy fun. Here there is seemingly no shortage of things a vacationer can do: Hiking, swimming, horseback riding, fishing, and boating. Plus, for those who want to
The Falls of Hills Creek, located east of the city of Richwood, West Virginia, are some of the most serenely majestic waterfalls in the United States. Sitting inside the perimeter of the Monongahela National Forest they have been a favored
If the beauty of unspoiled nature is your passion than the Highland Scenic Highway near Snowshoe WV is for you. The Highland Scenic Highway is entirely surrounded by the 19,000-acre Monongahela National Forest. It is 43 miles of natural beauty. This quiet


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In the Spotlight - Nestle exec takes helm at Carrefour
After months of speculation over the future of Carrefour CEO José Luis Durán, today's (18 November) news that the retail giant has appointed his successor came as little surprise. However, the French group's move to hire Nestle executive Lars Olofsson did raise eyebrows. Dean Best looks at Durán's departure and the challenges ahead for the Nestle veteran.
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A BUNDABERG man was brutally bashed and teenager Jacob Donnell helped the attacker, his sister's boyfriend, dump the badly injured victim's car.
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If You Read One Article About Experts, Read This One
Maynard Cooper & Gale Attorneys
Maynard Cooper and Gale Law Firm is a fully established law firm situated in Birmingham. People in San Francisco and New York as well as their environs can also access these services as they firm has established offices there. If you are in Montgomery, Huntsville, Tuscaloosa and Mobile then so far no more as the firm has offices in these areas as well.
Since its established in 1984, continues to marvel the nation with its quality services. The firm boasts of more than 300 legal representatives. Maintaining sustained performance keeps Maynard Cooper & Gale Law Firm in the top 250 firms published by the National Law Journal every year.
The firm has national presence in the US. Even popular firms in Fortunes 100 Companies are clients benefiting from the services offered by Maynard Cooper & Gale Law Firm. Individuals, charities, new business establishments, local business groups, and state corporations, national and international organizations fall in the list of clients served by the firm.
It is important to understand that attorneys in the firm handle issues within the US and borders and beyond. Lawyers from Maynard Cooper and Gale Law Firm serve people with cases in all industries. Trust the firm in using modern technology to handle your case. Technology has helped the firm expand its business to deal with case across the border.
Covered areas include financial and banking services, aerospace, automotive, healthcare, manufacturing, and insurance, education, natural science, and government. The grouping includes but not limited to consumer products, construction, real estate, biotechnology, retail and consumer products, commercial transport, maritime and pharmaceuticals.
The firm highly regards centering on individual customers in its philosophy while at the same time responding to their contemporary needs. Maynard Cooper and Gale Law uses experience, quality skills, creative ideas in courtrooms and extensive knowledge to offer quality service to clients. Since it was started in 1984, Maynard Cooper and Gale Law Firm has always secured a place on the B.T.I Client Service A-Team.
Broadly, the number of people served by Maynard Cooper and Gale Law Firm are many. Notably the company deals with companies on the Fortune 100 companies list, national organizations, international establishments, local and state corporations as well as non-governmental institutions. Maynard Cooper and Gale Law Firm attorneys serves both emerging businesses and medium-sized companies.
It is a requirement at Maynard Cooper and Gale Law Firm for attorneys to fully understand the industry besides being adequately skilled. To qualify for employment at the firm, a lawyer must fully comprehend corporate law, litigation, commercial and banking law, labor and employment, securities law, public finance, antitrust and government contracts. Additional areas where the firm's attorneys have enormous experience are bankruptcy law, environmental law, health care, intellectual property federal and state tax, maritime and admiralty as well as regulations of international trade.


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Explorează subiecte asemănătoare
How To Choose Colours That Work Well Together – Infographic | Cool Daily Infographics
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What to expect from the Obama administration on Cybersecurity
By Norman Johnson
The first Obama administration jumped out of the gate in 2009 with a nationwide review of cyberspace, headed by Melissa Hathaway. By May 2009 Cyberspace Policy Review was released with much fanfare. "This new approach starts at the top, with this commitment from me: From now on, our digital infrastructure - the networks and computers we depend on every day - will be treated as they should be: as a strategic national asset," Obama said. "Protecting this infrastructure will be a national security priority. We will ensure that these networks are secure, trustworthy and resilient. We will deter, prevent, detect, and defend against attacks and recover quickly from any disruptions or damage." The recommendations in the review were received positively by the security community and set high expectations.
A major recommendation of the Review was to appoint an interagency cybersecurity policy official and was fulfilled in Dec 2009 with the appointment of Howard Schmidt as the White House cybersecurity coordinator with cabinet and Presidential access. Although in the following years President Obama and Schmidt have been relatively quiet, the Obama administration has been active on many fronts, addressing many of the recommendations in the Review, for example, developing a joint Defense-Homeland Security guidance (Oct 2010), coordinating an international cybersecurity initiative (May 2011), proposing a plan for National Strategy for Trusted Identities in Cyberspace (Jun 2010), and unveiling a unified research and development strategic plan (Dec 2011).
Most of the activities in the first administration were policy actions, which did not directly impact companies and operations. What can be expected from the second Obama administration? A recently proposed Presidential directive outlines provides major clues: the "Critical Infrastructure Protection and Resilience Presidential Policy Directive" or Cybersecurity Executive Order (CEO), first circulated for comment in Sept 2012 and was made available to the public in Nov 2012. While the focus of the order is critical infrastructure protection (CIP), the type of infrastructure covered by the CEO differs from prior CIP directives, in that cybersecurity in a modern economy impacts all aspects of society, from traditional infrastructures, such as energy production and distribution, to new information infrastructures found in financial and economic sectors.
Why was an executive order needed? The CEO was in response to the failed Senate legislation, Cybersecurity Act of 2012(S.3414), on Aug 2, 2012 that was backed by the Obama administration. The goal of the legislation was to consolidate the oversight and regulation of the private sector cyberspace within the Dept of Homeland Security (DHS) as recommended in the Policy Review, but the legislation was rejected because opponents said it would lead to undue government regulations of the private sector. With the continued divided Congress, there is little expectation that a new cybersecurity legislation will be passed. Hence, the proposed CEO implements parts of the legislation, but is limited because only legislation can change or create new regulatory authority. Instead of a consolidated approach within DHS, the proposed CEO requires all agencies with regulatory control over critical infrastructures, under the coordination of DHS, to 1) identify critical infrastructure at risk and prioritize them – to be completed within 150 days of the date of the order, 2) develop a Framework to reduce cyber risk to critical infrastructure – to be finalized within one year, 3) establish and invite owners and operators of critical infrastructure to adopt voluntarily the Framework, and 4) propose regulations to implement the Framework within each infrastructure sector – within one year. The Executive Order differs from the Senate legislation S.3414 primarily by seeking a multi-agency regulatory solution, coordinated by DHS, rather than a centralized regulatory solution. Furthermore, because some cyber infrastructures are not currently regulated - such as financial networks, these will be exempt from the Executive Order.
While the details of the impact on the public sector by the Executive Order depend on the Framework that will be developed and the prioritization of the infrastructures (highest priority ones will be affected soonest), the final outcome will be some form of cybersecurity regulations. The new regulations will in turn result in increased certification and auditing activities. Whether or not there will be a common need for software and services to support the new regulations across all infrastructures will depend on the success by DHS in coordinating across multiple agencies.
So is increased cyberspace regulation of public sector likely in the second Obama administration? Definitely. And is the a new industry to be arise around regulation, certification and compliance?
Quite likely.


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USA -(Ammoland.com)- The election is here. And now the future of Ohio, and the country, is in YOUR hands.
Download our Pro Gun Voter Guide so that you can VOTE YOUR GUN RIGHTS.
It is vital that you vote in EVERY race. Your choice for President is important. But so are your choices for every office all the way down the ticket.
Buckeye Firearms Association voter guideIn addition to our Voter Guide, here are other resources:
Voter App – Create a personalized pro-gun voter guide on any mobile device or computer.
Where to Vote – Find your polling location.
View Your Sample Ballot – See the ballot for your voting location.
Trump vs. Clinton on Your Gun Rights
Donald Trump – "I will never let you down. I will protect our Second Amendment. I will protect our country."
Hillary Clinton – "The Supreme Court is wrong on the Second Amendment. And I am going to make that case every chance I get."
About Buckeye Firearms Association:
Buckeye Firearms Association is a grassroots political action committee dedicated to defending and advancing the right of Ohio citizens to own and use firearms for all legal activities. Visit: www.buckeyefirearms.org.
This post Vote for Candidates Who Support your Second Amendment Rights! appeared first on AmmoLand.com Shooting Sports News .
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Miller's Ale House
Coral Springs
1915 N. University Drive
Coral Springs, FL 33071
- Mon - Tue 11:00 AM - 1:00 AM
- Wed - Sat 11:00 AM - 2:00 AM
- Sun 11:00 AM - 12:00 AM
About This Location
Welcome to Miller's Ale House – Coral Springs! We're a local restaurant and sports bar located on North University between NW 19th and 20th Streets, next to the Century Plaza and across the street from Wells Fargo Bank. Come hang out, watch sports, be yourself and enjoy the company of others without breaking the bank.
We are known for our wide variety of freshly prepared dishes, and daily lunch, dinner and cocktail specials. From Filet Mignon and original pasta dishes to fresh salads and our signature fresh, boneless chicken Zingers tossed in your favorite sauces, our extensive menu offers something for everyone.
With over 75 beer varieties, including sought-after foreign imports and craft brews, signature cocktail pitchers and loads of specialty drinks, we have you covered any day of the week!
If it's happening, it's happening here.
Memorial Day May 29
This Memorial Day we're honoring the men & women who serve our country. If you served in any Military Branch come dine with us on Memorial Day & receive 50% off your menu item!


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Autoimmunity (Autoimmunity)
Journal description
Current understanding of autoimmune disease is being increasingly underpinned by the new molecular sciences. Progress in this area has been little short of spectacular, and all clinical specialities now recognise autoimmunity as a major component of the diseases with which they are involved. Autoimmunity is an international, peer reviewed journal that publishes articles of clinical and basic science on the pathogenesis, immunology, genetics, molecular biology, and treatment of autoimmune diseases. In addition to the basic mechanisms and elements of the immune system, the journal focuses on the autoimmune processes associated with systemic lupus erythematosus, rheumatoid arthritis, Sjogren syndrome, diabetes, multiple sclerosis, and other systemic and organ-specific autoimmune diseases. The journal is not restricted to any disease type or clinical speciality, but reflects the areas where scientific progress is most rapid and clinical applications significant and widespread. The journal is valuable to clinicians and researchers in immunology and molecular biology.
RG Journal Impact: 2.62*
RG Journal impact history
|2017 RG Journal impact
|Available summer 2018
|2015 / 2016 RG Journal impact
|2014 RG Journal impact
|2013 RG Journal impact
|2012 RG Journal impact
|2011 RG Journal impact
|2010 RG Journal impact
|2009 RG Journal impact
|2008 RG Journal impact
RG Journal impact over time
Additional details
|Cited half-life
|Immediacy index
|Article influence
|Autoimmunity website
|Material type
|Internet resource
|Document type
|Internet Resource, Computer File, Journal / Magazine / Newspaper
Publisher details
Publications in this journal
Article: Complex interaction between HNRNPD mutations and risk polymorphisms is associated with discordant Crohn's disease in monozygotic twins
- [Show abstract] [Hide abstract] ABSTRACT: Systemic lupus erythematosus (SLE) is a polygenic pathological disorder which involves multiple organs. Self-specific B cells play a main role in the lupus pathogenesis by generating autoantibodies as well as by serving as important autoantigen-presenting cells. Autoreactive T lymphocytes, on the other hand, are responsible for B cell activation and proliferation, and cytokine production. Therefore, both factors promote the idea that a down-modulation of activated self-reactive T and B cells involved in the pathogenic immune response is a reasonable approach for SLE therapy. Annexin A1 (ANX A1) is expressed by many cell types and binds to phospholipids in a Ca(2+) dependent manner. Abnormal expression of ANX A1 was found on activated B and T cells in both murine and human autoimmunity, suggesting its potential role as a therapeutic target. While its role on T lymphocytes is through formyl peptide receptor-like molecules (FPRL), and the formed ANX A1/FPRL pathway modulates T cell receptor signalling, there is still no fool-proof data available for the role of ANX A1 in B cells. We employed a lupus model of Balb/c mice with pristane-induced SLE which very closely resembles human lupus. In the present study, we investigated the possibility to modulate the autoimmune response in a pristane-induced mouse model of SLE using an anti- ANX A1 antibody. Administration of this monoclonal antibody resulted in the inhibition of T-cell activation and proliferation, suppression of IgG anti-dsDNA antibody-secreting plasma cells and of proteinuria, decreased disease activity and prolonged survival compared to control group.
Article: Aberrant function of myeloid-derived suppressor cells (MDSCs) in experimental colitis and in inflammatory bowel disease (IBD) immune responses[Show abstract] [Hide abstract] ABSTRACT: Background and aims: Myeloid-derived suppressor cells (MDSCs) encompass a novel population of suppressor cells and a potential candidate for cell-based therapies in inflammatory diseases. Herein, we investigated their immunomodulatory properties in experimental inflammatory colitis and T cell-mediated immune responses in inflammatory bowel disease (IBD) patients. Methods: MDSCs (defined as CD14(-)HLA(-)DR(-/low)CD33(+)CD15(+)) numbers were determined in peripheral blood (PB) from IBD patients. PB MDSC function was assessed in vitro. Experimental colitis was induced upon 2,4,6-trinitrobenzene sulfonic acid (TNBS) treatment and MDSCs were characterized by flow cytometry. The in vivo suppressive potential of bone marrow (BM)-derived MDSCs (BM-MDSCs) was tested by using both depleting and adoptive transfer strategies. Results: MDSCs were enriched in the periphery of IBD patients during active disease. TNBS colitis induced amplification of MDSCs, particularly of the granulocytic (Ly6G(+)) subset during the effector phase of disease. Of interest, BM-MDSCs potently suppressed CD4(+ )T cell responses under steady state but failed to control colitis-associated immune responses in vivo. Mechanistically, under the colonic inflammatory milieu MDSCs switched phenotype (decreased proportion of Gr1(high) and increased numbers of Gr1(low)) and downregulated CCAAT/enhancer-binding protein beta (CEBPβ) expression, a critical transcription factor for the suppressive function of MDSCs. In accordance with the murine data, human CD33 (+) CD15(+ )MDSCs from peripheral blood of IBD patients not only failed to suppress autologous T cell responses but instead enhanced T cell proliferation in vitro. Conclusions: Our findings demonstrate an aberrant function of MDSCs in experimental inflammatory colitis and in IBD-associated immune responses in vitro. Delineation of the mechanisms that underlie the loss of MDSCs function in IBD may provide novel therapeutic targets.
Article: Baseline adiponectin and leptin levels in predicting an increased risk of disease activity in rheumatoid arthritis: A meta-analysis and systematic review[Show abstract] [Hide abstract] ABSTRACT: To determine the pathogenic role of adipokines, such as adiponectin and leptin, in rheumatoid arthritis (RA) by investigating whether serum levels of these adipokines correlated with disease activity in RA patients. Medline, Cochrane, EMBASE and Google Scholar were searched for studies published until 5 November 2015 reporting serum levels of leptin and adiponectin and measures of disease activity including DAS scores and radiographic progression scores (such as total change in SHS scores and number of erosions). Secondary outcomes included pain scores, functional status and health questionnaires. Only randomized controlled trials, cohort studies, or two-armed prospective or retrospective studies were included. A χ(2)-based test of homogeneity was performed using Cochran's Q statistic and I(2). A total of 917 predominantly female participants (average age range, 39-56 years) from six prospective cohort studies were included for assessment. A fixed-effects analysis was applied for leptin levels due to lack of heterogeneity among the studies (Q = 4.4364; I(2 )=( )32.38). A random-effects analysis was applied to serum levels of adiponectin because of significant heterogeneity between studies (Q = 4.444, I(2 )=( )77.50%). Serum leptin levels were higher in RA patients with high disease activity (pooled SMD: 0.53, 95% CI: 0.24-0.82); however, serum adiponectin levels did not correlate with RA disease activity (pooled OR: 1.38, 95% CI: 0.77-2.47). The meta-analysis provides an additional factor to determine high disease activity index in RA, that is, serum leptin levels, which can be of benefit when choosing treatment strategies.
Article: Anti-calreticulin antibodies and calreticulin in sera of patients diagnosed with dilated or hypertrophic cardiomyopathy[Show abstract] [Hide abstract] ABSTRACT: Distinct cellular level of the Ca(2+)-binding chaperone calreticulin (CRT) is essential for correct embryonal cardiac development and postnatal function. However, CRT is also a potential autoantigen eliciting formation of antibodies (Ab), whose role is not yet clarified. Immunization with CRT leads to cardiac injury, while overexpression of CRT in cardiomyocytes induces dilated cardiomyopathy (DCM) in animals. Hence, we analysed levels of anti-CRT Ab and calreticulin in the sera of patients with idiopatic DCM and hypertrophic cardiomyopathy (HCM). ELISA and immunoblot using human recombinant CRT and Pepscan with synthetic, overlapping decapeptides of CRT were used to detect anti-CRT Ab. Serum CRT concentration was tested by ELISA. Significantly increased levels of anti-CRT Ab of isotypes IgA (p < 0.001) and IgG (p < 0.05) were found in patients with both DCM (12/34 seropositive for IgA, 7/34 for IgG) and HCM (13/38 seropositive for IgA, 11/38 for IgG) against healthy controls (2/79 for IgA, 1/79 for IgG). Titration analysis in seropositive DCM and HCM patients documented anti-CRT Ab detected at 1/1600 dilution for IgG and 1/800 for IgA (and IgA1) and at least at 1/200 dilution for IgA2, IgG1, IgG2 and IgG3. Pepscan identified immunogenic CRT epitopes recognized by IgA and IgG Ab of these patients. Significantly increased levels of CRT relative to healthy controls were found in sera of patients with HCM (p < 0.01, 5/19). These data extend the knowledge of seroprevalence of anti-CRT Ab and CRT, and suggest possible involvement of autoimmune mechanisms directed to CRT in some forms of cardiomyopathies, which are clinically heterogeneous.
- [Show abstract] [Hide abstract] ABSTRACT: Objectives: Recent evidence has demonstrated that CD3ζ (also called CD247) play a vital role in multiple autoimmune diseases. In this study, we explored the association between CD247 gene single-nucleotide polymorphisms (SNPs) and rheumatoid arthritis (RA) in a Chinese Han population. We also evaluated the CD3ζ expression profile in peripheral blood mononuclear cells (PBMCs) from patients with RA and health controls. Methods: Three CD247 polymorphisms (rs704853, rs1214611 and rs858554) were studied in 612 patients with RA and 848 controls in a Chinese population. Genotyping was performed using the Fluidigm 192.24 Dynamic Array™ Integrated Fluidic Circuit (IFC). For gene expression study, CD3ζ mRNA levels of 36 patients with RA and 39 healthy individuals were assessed by real-time polymerase chain reaction (RT-PCR). Data were analyzed by SPSS 11.5 software. Results: A significant association between rs858554 polymorphism and RA was found under all genetic models (all p < 0.05). Moreover, we found the genotype distribution and allele frequency of rs858554 were significant associated with ACCP(+) and RF(+) phenotype as compare to health controls (all p < 0.05). Unfortunately, we did not detect any significant associations between rs704853, rs1214611 and RA susceptibility and autoantibody profiles (all p > 0.05). The gene expression assays showed that CD3ζ mRNA levels were downregulated in PBMCs of patients with RA when compared to healthy controls. Conclusions: Our results, the first reported for distinct Chinese populations, support a role of the CD247 gene in the susceptibility to RA. Further studies with more sample size are necessary to clarify the exact role of CD247 gene in the pathogenesis of RA.
Article: Ureido group-specific antibodies are induced in rabbits immunized with citrulline- or homocitrulline-containing antigens[Show abstract] [Hide abstract] ABSTRACT: The specificities and cross-reactions of antibodies induced by citrulline- and homocitrulline-containing proteins may give implications on the role of citrulline- and homocitrulline-binding antibodies in the pathogenesis and progression of rheumatoid arthritis (RA). Here we use rabbits as an experimental model of antibody development in RA. Thirty-two animals were immunized with peptide antigens containing either homocitrulline or citrulline. The sera were tested for binding to CCP and MCV antigens and to peptide sequences related to carboxyterminal telopeptides of type I and II collagens and containing arginine, citrulline, or homocitrulline. The binding of CCP and MCV antigens to antisera against homocitrulline-containing immunogens could be inhibited by human serum albumin containing homocitrulline, whereas similar binding to sera against citrulline-containing immunogens was not inhibited. The antisera induced with citrulline-containing collagen telopeptides recognized type I collagen-related antigens in a sequence-specific manner, as antibody binding to both citrulline- and homocitrulline-containing peptides was inhibited by corresponding citrullinated and native peptides. In contrast, type II collagen-related peptides were recognized by the antisera in a ureido group-specific manner, as their binding to homocitrulline-containing peptide was inhibited by both citrulline- and homocitrulline-containing, but not native peptide. Binding of the citrullinated type II collagen peptide could only be inhibited by the similarly citrullinated peptide. In conclusion, antibodies induced with citrulline or homocitrulline-containing antigens bound antigens in a ureido group-specific manner, recognizing citrulline and homocitrulline also in other sequences than those used in the original immunization. In competitive situations the amino acid present in the immunization antigen was favored.
Article: Association between the three functional miR-146a single-nucleotide polymorphisms, rs2910164, rs57095329, and rs2431697, and autoimmune disease susceptibility: A meta-analysis[Show abstract] [Hide abstract] ABSTRACT: Studies suggest associations between the miR-146a single nucleotide polymorphisms (SNPs) and susceptibility to autoimmune diseases. However, the results are inconsistent and inconclusive. Therefore, the aim of this study was to arrive at a conclusion about the association between the three functional miR-146a SNPs and autoimmune disease risk. Studies were identified through PubMed/MEDLINE searches for studies published up to January 2016 using as keywords rs2910164, rs57095329, rs2431697, and miR-146a polymorphisms. Thirty studies were included in the meta-analysis. The SNP rs2910164 G > C was found to be associated with increased risk of multiple sclerosis (CC + CG versus GG, OR = 1.25, 95% CI: 1.01-1.55), with decreased risks of psoriasis (C versus G, OR = 0.81, 95% CI: 0.69-0.96; CC versus GC + GG, OR = 0.73, 95% CI: 0.56-0.94), Behcet's disease (CC versus GC + GG, OR = 0.60, 95% CI: 0.50-0.73), asthma (C versus G, OR = 0.80, 95% CI: 0.69-0.93; CC versus GC + GG, OR = 0.65, 95% CI: 0.48-0.86), and uveitis (CC + CG versus GG, OR = 0.61, 95% CI: 0.49-0.77). The SNP rs2431697 C > T was found to be associated with an increased risk of SLE (T versus C, OR = 1.26, 95% CI: 1.15-1.38; TC + TT versus CC, OR = 1.28, 95% CI: 1.03-1.58; TT versus TC + CC, OR = 1.40, 95% CI: 1.21-1.62). The SNP rs57095329 A > G was found to be associated with an increased risk of SLE (G versus C, OR = 1.25, 95% CI: 1.17-1.35). The miR-146a SNPs rs2910164, rs57095329, rs2431697 are associated with susceptibility to certain autoimmune diseases. However, for other autoimmune diseases, they may be protective or insignificant.
Article: Aberrant expression of long noncoding RNA TMEVPG1 in patients with primary immune thrombocytopenia[Show abstract] [Hide abstract] ABSTRACT: TMEVPG1 is a long noncoding RNA, which can promote Interferon gamma (IFNG) transcript as an enhancer. It has been reported that plasma IFNG concentration was elevated and partly due to dysregulation of micro RNAs in patients with primary immune thrombocytopenia (ITP). However, the effect of long noncoding RNA on IFNG expression in ITP is currently not well understood. To explore whether TMEVPG1 is involved in ITP, this study examined the TMEVPG1 expression and analyzed the association between TMEVPG1 transcript and IFNG expression in patients with ITP and healthy controls. The result showed that TMEVPG1 expression in peripheral blood mononuclear cells (PBMCs) from active ITP patients were lower than in that of healthy controls. Further activation for 24 h in vitro resulted in decreased TMEVPG1 while elevated IFNG mRNA and protein expressions in activated PBMCs compared with un-activated PBMCs both in ITP patients and healthy controls. However, TMEVPG1 and IFNG mRNA had same up-regulated tendency after short-time activation (1, 2 and 4 h) in healthy controls. In addition, we detected T helper 1 (Th1) cell associated transcription factors T-bet, STAT1 and STAT4 mRNA levels, and found T-bet mRNA expression was lower in PBMCs from ITP patient in remission compared with healthy controls. In conclusion, we speculated that TMEVPG1 could promote IFNG transcription, and IFNG over-expression negative feedback regulated on TMEVPG1 expression, which resulted in decreased TMEVPG1 in ITP patients.
- [Show abstract] [Hide abstract] ABSTRACT: Primary immunodeficiences are often accompanied by autoimmune phenomena. IL-12 receptor deficiency is a well characterized primary immunodeficiency that leads to propensity to intracellular infections mainly with mycobacteria and Salmonella. We report on two patients with IL-12 receptor β1 deficiency that presented with autoimmune manifestations and photosensitivity dermatitis and describe possible pathogenetic mechanisms leading to development of clinically significant autoimmune phenomena.
Data provided are for informational purposes only. Although carefully collected, accuracy cannot be guaranteed. Publisher conditions are provided by RoMEO. Differing provisions from the publisher's actual policy or licence agreement may be applicable.


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March 11, 1929
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Monday, March 11, 1929
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Saturday, March 9, 1929
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Tuesday, March 12, 1929
Mason City Globe Gazette
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Mason City Globe Gazette
Mason City, Iowa
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Mason City Globe-Gazette (Newspaper) - March 11, 1929, Mason City, Iowa MASON CITY G x MONDAY MARCH 11 1929 lampton Girl Receives High Honors at Ames HAMPTON March Lucy Ifhompson daughter of Mr and Mrs ill G Thompson of Hampton was DILI i of the 21 girls with the highest aver ages in the freshman class at Iowa State College at Ames during the last quarter Miss Thompson is a gradu ate of the Hampton high school and an active in 4H ctub work DOCTORS SHOW WAKE UP WITHOUT COLD any Here End Head Cold and Chest Cold in Few Hours at Home by Hospital Meihod The pleasure of quick relief a nights Bleep and waking up the morning without the misery and danger ot a head cold cough or chest cold This brieflyIs the substance of reports tiafi hundreds of Mason City Mrs W II Burnetts found quick relief through a pleasant and inexpensive homo method recommended by hospital hysicians Burnette for example was reated for a severe cold which startuI ln her noss passages and had spread llown towards her chest causing fear f pneumonia Doctors Immediately prescribed double doses ot Aycrs yhcny concentrated mix cf wild cherry und otheiIngredients which have re Jeved even the most extreme hospital Kelicf began with the first pleas ant swallow She felt its comforting healing her nasal pas sages deep down into her chest In a few hours the cold hail cleared up noticeably and that night she breathe 1 freely and didnt cough once In an other day or so doctors report all traces oE the cold were rone Note See other cases reported certified by attending phy sicians This hospital medicine penetrates and heals inflamed linings of the breathinpr passages Absorbed by the system it quickly reduces holps allay that feverish prinpy feel ing find arises out the rnld frnm the noso passages throat and ohopt Just a fow pleasant siioonsfuls of Cherry TVrtnral now and youll teo lilre a differcnt person tomorrow Al nil drugfxistH URICK SAYS IOWA EMPLOYMENT IS mm INCREASED Many Industries Delayed by Weather and Bad Road Conditions DES MOINES 11 dustry In Towa now faces the most favorable period In years A L Urluk state lahor commissioner said today in his employment survey for Feb ruary Reporting a general increase of 22 per cent In Industry employment for February over January Uricfc says Many of the industries are now being delayed by unseasonable weather and bad road conditions which mean longer callinff intervals and greater sales effort to maintain volume How ever from all Indications wo are Just entering a period that Is bringing to industry tho most favorabte oppor tunities for better and business generally than has been visioned In a ot years In Iowa Only two ot the seven larger cities of tbo state she ed tbo trend of em ployment for Fcbrxiary as less than for January Sioux City reported n 2 per cent decrease d Burlington a 14 per cent falling off Davenport re liorted the greatest Increase 142 per cent with Waterloos 65 per cent In crease the o y other city reporttns morp thnn 1 per cent The monthly survey also shows that the number of person employed dur ing January this year was greater than for any January in the last five years The total ot 40523 men and women occupied In 11 types of indus tries was nnre than 3000 greater than for January 1027 tha second highest total since During the second month of the new year a complete recovery la seen of the holiday activity Mr Uriel said Tho Ircronse reported for the month Is a result largely oC the nor mal stride attained hy the larger in iluslrlal groups assisted materially with the expansion projects In some of the larser manufacturing establish ments 350 Odd Fellows of Hampton Listen to Childrens Program HAMPTON March of th3 largest gatherings of Odd Fellows and Rebekahs ever held In in tho I O O F hall bore took place Friday evening when 350 members of the orders gath ered to hear aprogram presented by a group of children from the Odd Fel lows home at Mason city Dinner was served at 7 oclock Two File in Thornton School Board Election THORNTON1 March con solidated school district of Thornton Is holding an election today to select two directors to succeed Jesse Brogan an 1 John Gaspers whoso terms expire The names which have been filed with tlie secretary Paul James are Art Thada and John Caspers PIVBT POLICE GRAFT IS BLAMED FOR CRIME Judge Says 20 Per Cent of Chicagos Officers Are Dishonest CHICAGO March 11 doiigtgettinB policemen estimated as 20 per cent ot tho force were blamed by Juflgo Frank Comerford last night for tho presence of organ ized crime in the city Wo know that organized crime cannot exist without police conni vance1 he tola tho Sunday evenlns club of Downers Grove Probably SO per cent of the police department Is honest but the other 20 per cent is made up of the boys with an in A policy of millions for extermina tion but not one cent for tribute vtis urged by Judge Comerford He sug gested giving the police commissioner unlimited power and then accept no excuses Politicians who bargain with crime should be sent to the penitentiary he said anot the bar association should clean out its members who are guilty of fixing framing and other un ethical practices High Ranking Senior at Iowa University Will Get Prize IOWA C1TV March Uni versity of Iowa senior having thta highest promise oC achievement in graduate study will receive the annum prize of this spring according lo Dean Carl K Seashore of the grml uate college By terms of the will of the late Theodora F Sanxay longtime rosi icnt of Towa City the sum Is offered to candidates who are natives or dents of irt state Definite plans for graduate study must be presented The advanced worl may be taken at the of Towa or at uuy other approve1 institution Nominations will be made by the faculty of the graduate college before March IS Dorothy 15 Scott of Slbley Is the holder of the 192829 award Rockford 0 E S Has School of Instruction nOCTCFCmn March an nual school of Insfuctton for the members and officers of llio Eastern Star was Conducted hv Mrs Nornvi fjanlon Cbarlpg City FrWlv nftor noon and evening A oclock din ner was served to SO members and visitors by Mrs L IT Blddlck Mr and Mrs A W Lohr Mrs John Allen Mrs Klla Lindsay Mrs Fannie notch Kiss Mr and Mrs B P Aycrs Mr and Mrs R P Deunkelberg and Mrs Aung KVinnongrnlscM Telephone Company Organizes for Year LAKE March The board of directors of tCenter1 toivn ship telephone company met and or ganized for the coming year Satur day Tho officers who will servo are A O Brae ey president Leonard Thompson secretary nnd Tlico Ijelstad treasurer course times have changed Wouldnt it bo awful It thpv hnrtivV Variety is a great help in making life worth NensRepuhli ran for that welldressed feeling Get that Marshall Swift touch of smartness moulded into your spring coat by the best pressing experts in town Just ordinary drycleaning will not do Just ordinary pressing is not good enough for you Not when you can get Marshall Swift crafts manship for the same money The Marshall Swift pro cess actually refreshes and revives the fabric It gives the fabric the feel as well as the looks of newness Colors have snap and life Linings gleam and glint with freshness Fur trimmings are glazed and revived amazingly But it is in the chic air and tailorlike smartness that Marshall Swift crafts manship reveals itself es pecially Shape and lines are expert ly moulded in Edges are pressed thin kept true and straight The coat fits neck and shoul ders Yes Theres a difference Thats why over 10000 homes preferred Marshall Swift skill and service last year PLEASE HURRY This year more than ever you should send early to insure the best of service Easter is nine days earlier The inclement weather has de layed the Spring rush Avoid disappointment and delay by sending now SWIFT Inc CLEANERS and FURRIERS PHONE 788 or 789 CRAFTSMEN IN KEEPING THINGS NEW A Few Words About Marshall Swift Service This spring we can render you a complete head to foot wardrobe service as well as renovating your many household articles Read the List GARMENTS Cleaned and Pressed Repaired Altered Dyed HATS Cleaned Reblocked Retrimmed SHOES Repaired FURS Cleaned Repaired Remodeled Stored DRAPES Cleaned and Pressed RUGS Cleaned Resized Refringecl Overedged ENCLOSED CARS Cleaning of Rugs and Upholstery UPHOLSTERED FURNITURE Cleaned MothProofed HEMSTITCHING PLEATING BUTTON COVERING To OutofTown Folks For miles around our Irnrlts firo lit your vicinity uiro This At VON i Dour lieiiiff re liirricff promptly and In Korifl condition rSi GAY DAYS AND BRILLIANT 1 NIGHTS t New Modes and Skinners Crepes TTKnB comesspvlnsi and the mil for color and more color And hoi0 arc tho now SUInnerH OepcH in nil tlie lovely shades that Fashion favors For your sports frocks afternoon dresses and eve runfiowns tliiso incomparable fahrlcs are tlie very last word Sott rich draping perfectly In slender lines yet with tliat famed Skinner wearing ouility TRY OUR CUTTING AND PITTING SERVICE Skinners Crepes DAMONIGOU CO ITS NOT A HOME UNTIL ITS ILANTT7D A house wihiftut the softening beauty of trees shnibs vines and Bowers looks stark naked and uninviting NotiiUnmc Until Its Planted Plan now the planting you will do this spring Let Us Help Make Your Ground Beautiful Well gladly fld vise yon just what you need and varieties will give the best and quickest results xt ihe Sherman Nursery Co CHRALES CITY IOWA Occasional Blemishes Try it today You will sure to like its clean tonic odor also the way it clcfinscs nnd livens the skin At all For free ftRcnpla of each writeDrpl41Reimol Baltimore Md esinol Almost everyone has ugly pim ple or bit of rashl Apply n little Kesinol Ointmcjit and see how quickly the soreness ia relieved and tho blemish disappears To keep the skin soft nnd lovely nothing can excel the daily use of Ilcsinol Soap SERVICE MEASURED NOT BY GOLD BUT BY THE GOLDEN RULE evcry rtclor can use the Be PrOlld Symbol oC Service w li i c h is pictured above As a matter of fact only OIK funeral director in a community is entitled to that privilogrc Only a funeral director who renders a complete and thoughtful service at a reasonable price may represent the Order of the Golden Rule in his community This is therefore a distinction in which one may very properly take pride MEYER FUNERAL HOME 243 FIFTH STREET SOUTHEAST or Night k 1505 ;
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