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Bb!! Thanks!! Post a pic of your test??? I so hope you are joining me !!!
Bb!! Thanks!! Post a pic of your test??? I so hope you are joining me !!!
Well it's clearer today, looks like a bfp! Was initially relieved to know for sure, now nervous as hell... And no symptoms is very scary! I've just had this feeling that even if it did happen this month, it won't be a sticky.
Fingers crossed I guess
Congrats to you both bluebridie and spideysmummy! it is great to hear good news
I am still in a dark mood, one of my very good friends has also had a MC last week... she was 12 weeks so now I can only think that you are not safe even at 12 weeks. Trying to be positive but still quite dark.
Huge congratulations Spideysmummy, bluebridie and mumofprincess. I love seeing these stories as it gives me hope that it will happen again for me too. Please keep us posted of your progress!
Gentoo - I'm so sorry to hear about your loss. I also had a blighted ovum with my first pregnancy only a month before yours. I'll second what bluebridie said about trying not to be hard on your DH. They don't have to deal with the emotions that we do but they do stress in their own way. My OH was very supportive and seemingly was coping well until he quit his job twice that week (lucky they didn't accept his resignation LOL). It does get easier over time, big hugs though
Ardora and delirium - sorry to hear you are going through tough times. You have both been through a lot. I get so frustrated when I see people not appreciating their children so much more now and even last week had a melt down to DH about us deserving much better than this because we are good people. It really isn't fair.
AFM - I had my 6 week followup last wk after my D&C. Specialist confirmed I have endo and gave me the option of TTC or a laparascopy. Given that we did fall pregnant in our 3rd month of trying, I'm keen to see if we can fall pregnant naturally again and will follow up with him again in 3-6 months if it hasn't happened. He wants me to see him ASAP to monitor my HCG closely and ultrasound ASAP if I do fall pregnant again so I am happy that I will be monitored closely to help with the worry. I'm currently CD9 and feeling really positive about TTC again. Fingers crossed this will be our month.
mumofprincess (21-08-2012)
Hi there - just wondering if I can join?
Had an ectopic 2 weeks ago with a resulting salpingectomy (tube removed). It would have been our 4th child and I am devastated.
I don't conceive easily (kids are 12, 6, 2 - we haven't used contraception in 13 years!) but losing this last one has made me really really want another one. So we've decided to actively ttc even though the odds are against us - I've been reading up on charting, vitex, acupunture - everything! We have to wait a couple of months but I'll be getting ready and following along in the meantime...
Hi ladies, wondering if I can join? I had a D&c last week after a miscarriage at 11 weeks- bubs was 9 weeks.
Wanting to ttc again ASAP - I guess we are just at the mercy of my cycle now...
We seem to conceive easily enough- first month we had a chemical and then second month (straight after) was this most recent bubs. They are. Just not feeling very sticky.
I have a three and a half year old DS but he has a different biological dad. I would never say to DH but sometimes I just get so freaked out that together we not compatible baby makers.
So waiting for O and this time going for opk's, preseed and smep. Hoping for a super quick result!!
Taking vitex now too and also helping this makes for a stickier bub. Not sure how much heartache we can take - tho as DH says - if we want a baby we just have to keep on going.
Sorry for the massive post.
Congrats to all the BFPs - it has made me hopeful xx
Congrats to those with pos pregs and commiserations to those joining this thread.
I started my period yesterday evening. Yay. Taking this as a good sign my body is getting back to normal after D&C. We plan to start TTC now, but hard not to feel a little apprehensive.
Hi all, looks like I'll be
Joining in here, I had a miscarriage 2 weeks ago at 9wks, it took us 18mths to conceive if
You can see my signature it
Hasn't been the easiest few years for us
Pregnant for the first-time?
Not sure where to start? We can help!
Our Insider Programs for pregnancy first-timers will lead you step-by-step through the 14 Pregnancy Must Dos!


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Jihad Academy
Format: Paperback
Language: English
Format: PDF / Kindle / ePub
Size: 10.68 MB
Downloadable formats: PDF
Pages: 176
Publisher: Bloomsbury India (February 9, 2016)
The Kingdom of God Is Within You (Barnes & Noble Library of Essential)
If it passes, Nevada will make history as the first state to vote to undo the marijuana prohibition. The group asserts that current marijuana laws don't work, that instead of curbing its abuse, the punitive approach has produced excessive and unjust punishments. Meanwhile, the distribution system is run by dangerous criminals who target mainly the youth and vulnerable populations. Furthermore, there were more arrests for simple marijuana possession than for violent crimes like murder, manslaughter, rape, and robbery , source: Opus Dei: An Archaeology of Duty (Meridian: Crossing Aesthetics) Opus Dei: An Archaeology of Duty. Derived probably from the Greek kuriakon (i.e., "the Lord's house"), which was used by ancient authors for the place of worship epub. However, it also makes writing in religious studies challenging because your instructors will expect you to use diverse theories and methods. At the same time that religious studies uses many of the same theories and methods as other fields, it is still its own discipline with unique conventions for writing. Writing for religious studies takes place within a secular, academic environment, rather than a faith-oriented community A New Reformation: Creation Spirituality and the Transformation of Christianity A New Reformation: Creation Spirituality. A., Philosophy of Religion and Theology, Claremont Graduate University, CA, 2002. Ruzgar's research interests include Islamic thought, contemporary philosophy of religion and theology, process philosophy and theology, religious pluralism, and interfaith dialogue. "Islam and Deep Religious Pluralism" in Deep Religious Pluralism, edited by David Ray Griffin (Louisville: Westminster John Knox Press, 2005). "Islam and Process Theology" in Handbook of Whiteheadian Process Thought, vol. 1, edited by Michel Weber and Will Desmond (Frankfurt; Paris; Lancaster; New Brunswick: Ontos Verlag, 2008). "God and the World: A Dynamic Relationship in the Qur'an" in Creative Transformation, Volume 20, Numbers 3-4, Summer/Fall 2011. "An Analysis of the Gülen Hizmet Movement's Interfaith Dialogue Activities" in The Gülen Hizmet Movement: Circumspect Activism in Faith-Based Reform, edited by Tamer Balci and Christopher L Communalism, Caste and Hindu Nationalism: The Violence in Gujarat read epub.
One Nation Under God: A Christian Argument in Favor of Separation of Church and State
Man's Dominion: The Rise of Religion and the Eclipse of Women's Rights (Routledge Studies in Religion and Politics)
Politics, Society and Christianity in Vichy France (Berg French Studies Series)
THE CHALLENGES OF ROGER WILLIAMS (Baptists)
The Universe Bends Toward Justice: Radical Reflections on the Bible, the Church, and the Body Politic
Where God Was Born: A Daring Adventure Through the Bible's Greatest Stories (P.S.)
The Problem with Christ; Why we don't understand Jesus, His enemies, or the early Church
Confucianism and Democratization in East Asia
The Curious Case of Kiryas Joel: The Rise of a Village Theocracy and the Battle to Defend the Separation of Church and State
Reflections of a Realist
America's Vision vs. God's Standard of Justice: Rethinking the American Dream
Liberty in My Soul
The Protestant ethic and the spirit of capitalism
Religion and Law: An Introduction (Ashgate Religion, Culture and Society Series)
Rated 4.2/5
based on 402 customer reviews

subset: commoncrawl


text:
Order now to get it by: Wednesday March 15 - Saturday March 18
This product ships with limited tracking information, and may take longer than usual to be delivered.
Condition: New
Product ID: 221130
Delivery Information |Returns & Exchanges |Payment Methods
High quality, lasting pants by Dickies These kids' Dickies pants are made of 65% polyester/35% cotton. Imported.


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3900 S Kyrene Road, Tempe, AZ 85282
4 beds, 5 baths, 2,780 sqft
Status: Active
Property Description
2780 Sq Ft Private Gated Remodeled Vintage Home Nestled on a Huge Lot. 2 Miles from ASU & walking distance to Light Rail & Orbit Routes. Close to Downtown Mill Ave for Nightlife. 4 Bedroom Suites with Private Bathrooms & Oversized Closets. Separate Office or Bonus Room, Separate Bedroom with Private Entrance. Tile Floor Throughout, French Doors to Patio & Resort Style Backyard Oasis, Open Floor Plan to Stunning NEW Eat-in Kitchen with Center Island, Granite counters, Glass Tile Backsplash, Pantry, NEW Upgraded Appliances, Breakfast Bar & NEW Wood Cabinetry with Stylish Hardware. Upscale Bathrooms with Designer Tile. Extended Backyard Covered Patio. Right Across from Upcoming Tempe Redeveloped Bike Trail Path.
Listing Information for 3900 S Kyrene Road Tempe, AZ 85282
Ceiling Fan(s),Multi-Zones
School Information for 3900 S Kyrene Road Tempe, AZ 85282
Room Information for 3900 S Kyrene Road Tempe, AZ 85282
Separate Bedroom Exit
Master Bedroom Walkin Closet
Breakfast Bar, Formal, Eat-in Kitchen
Pantry, Non-laminate Counter, Kitchen Island, Granite Counter-tops
3/4 Bath Master Bdrm,Private Toilet Room,Double Sinks
Dual Sinks
Interior Features for 3900 S Kyrene Road Tempe, AZ 85282
Microwave, Refrigerator, Electric Range/Cooktop, Disposal, Dishwasher, Dryer, Washer
Tile, Carpet
Electric Heating
No Interior Steps, Vaulted Ceiling(s)
Exterior / Lot Features for 3900 S Kyrene Road Tempe, AZ 85282
2 Garage Spaces, 2 Parking Spaces, Direct Entry from Garage, Electric Door Opener
Stucco, Stone, Painted
Composition Shingle
Hermosa Tracts Lots 7 & 8
Covered Patio(s)
Community Features for 3900 S Kyrene Road Tempe, AZ 85282
Park Play Area, Bus Line, Gated Community
Driving Directions to 3900 S Kyrene Road Tempe, AZ 85282
S Mill Ave to right onto W Southern Rd. Turn left onto S Kyrene Rd to your new Home.
Financial Considerations for 3900 S Kyrene Road Tempe, AZ 85282
Listing Price History for MLS#: 5418352
Tempe AZ Real Estate and Tempe AZ Homes for Sale
Tempe is located in the state of Arizona. The zip code of 85282 has a population of 164,139. The median age of people living in Tempe, AZ 85282, is 28.1 years.
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George westinghouse
Explore related topics
George Westinghouse was an amazing American who changed the world. He invented the air brake for trains. Until this invention, only locomotives had brakes and thousands died annually in train wrecks. Every train in the world today still uses his system. In addition, the AC power used all over the world was pioneered by Westinghouse. Edison wanted to use DC power because he could make more money but Nikolai Tesla convinced Westinghouse that AC was better . His impact on the world was huge.
Monument seen at the Niagara. Nikola Tesla and George Westinghouse built the first hydro-electric power plant in Niagara Falls and started the electrification of the world.
George Westinghouse - Wikipedia
George Westinghouse - Wikipedia
George Westinghouse - an inventor that has influenced the course of progress in the USA and a genuinely nice human being.
George Westinghouse
Who Made America? | Innovators | George Westinghouse, Jr. was born October 6, 1846 (died in 1914) famous for his work re alternating current... (AC vs DC) and more.
George Westinghouse-Edison got most of the credit, it's hard to argue that Westinghouse's contributions were almost as great as Edison's. Certainly it was his electrical system, which used alternating current based (a result of the work of Nikola Tesla, by the way), that ultimately prevailed over Edison's insistence on direct current and paved the way for the modern power grid. Westinghouse invented the railway air brake, which did much to improve the safety of the American railway system.
George Westinghouse - Founder of the Westinghouse Electric Company in 1866, Westinghouse was a well-known inventor and engineer of his time. He was awarded an astonishing number of patents over the course of his life. Before this success, he enlisted in the military as a teenager and served in two branches over a three-year period


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Search engine marketers have gathered in Las Vegas for WebmasterWorld's World Of Webmasters Search Conference that runs
three days this week. A rundown on search coverage from the first day of the event is below:
- WebmasterWorld of Search Conference, Day 1 from Search Engine Lowdown
mainly covers the session about big site issues.
- Search Engine Friendly Design and Coding (Especially Flash) from Search Engine Roundtable covers using CSS
to tighten code and dealing with Flash from an SEO perspective.
- Super Session: History of SEO/SEM Theory and Testing from SE Roundtable covers a few tips but more some
interesting history and experiences in testing by long-time SEO vets to get the "perfect page" for search engine rankings.
- PFI Topics and Issues – from SE Roundtable is a look at paid inclusion.
- Informal Discussion with Tim Mayer and the Yahoo! Search Folks covers kicking back with Yahoo's Tim Mayer, a
veteran of the search industry, and talking about search forums, official search engine blogs and other topics.
All but one of the articles above is from Barry Schwartz of Search Engine Roundtable and one of our forum moderators (RustyBrick), providing his usual great conference coverage.
Barry does the same for our own SES shows and will be back at it when SES Chicago happens next month. Meanwhile, here
are links to coverage he provided from our SES San Jose and Stockholm shows earlier this year:
In our Search Engine Watch Forums, we also have an entire area devoted to discussion and coverage of search-related
events. Some recent threads of interest are:
- 2005: Conference listings: A call for people to list interesting shows and events for next year.
- WebmasterWorld World of Search Conference #7: No discussion of the show yet, but that may come.
For now, mainly a place for people to coordinate meet-ups.
- Search Engine Strategies Events: SES Chicago this year or SES New York next year? I and others
offer some advice to a person trying to decide.
- Ad:Tech New York: Andrew Goodman provides a long post on interesting search sessions out of the
show earlier this month.
And via John Battelle's blog, news that the venerable Search Engine Meeting has
posted its new agenda for next year. The conference takes an academic look at search both on the web and
across the enterprise.
Related reading
Can Pinterest crack (and monetise) visual search?
Pinterest made a clear declaration of intent last week with the announcement that Randy Keller, Google's former head of image search, has joined the photo sharing site as Head of Search.
What we can learn from the latest trends in voice search
Voice search is already a fast-rising trend in the search industry, and its latest developments indicate that it's starting to win ground in daily use.
How can you successfully set up an efficient business blog on a very tight budget?
Setting up online presence for your business can be overwhelming. So much to plan and so much to invest (in terms of both time and money).
What is influencer marketing, and why should it be part of your digital strategy?
If I tell you I have the secret formula for any entrepreneur to succeed, you may not believe me. But if Neil Patel, New York Times best selling author and a person The Wall Street Journal calls 'the web's top influencer' tells you, "My secret formula is the greatest", you will probably believe him.


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Utah Schools for the Deaf and the Blind - Administration and Ogden Campus
Address: 742 Harrison Boulevard (1200 E)
Ogden, UT 84404
Ogden, UT 84404
Phone: 801-629-4700
Fax: 801-629-4896
Service Categories:
URL: http://www.usdb.org
Eligibility: Hearing and/or visual impairment. Birth to 21 years of age and their families
Wheelchair Accessible: Complete
Services Provided: Provides consultation, resources, and direct educational services to children with hearing and/or visual impairment and their families.
|Original Source:
|MedHome Portal
|Last Updated:


text:
Royals place pitchers Young, Medlen on 15-day D.L.
Starting pitchers Chris Young and Kris Medlen were both placed on the 15-day disabled list on Thursday afternoon.
Royals score early, beat Yankees to snap losing skid
The Kansas City Royals beat the New York Yankees 7-3 on Wednesday night at Yankee Stadium.
Sporting KC loses to Colorado on late 2nd half goal
Sporting Kansas City lost to the Colorado Rapids 1-0 on Wednesday night.
Scherzer ties MLB record with 20 strikeouts in Nationals win
Max Scherzer struck out 20 batters, matching the major league record for a nine-inning game as he pitched the Washington Nationals past the …
Washburn baseball prepares for MIAA Tournament
Washburn baseball begins its MIAA Tournament run on Thursday morning at 9:00 a.m. against Northeastern State.
K-State to host 11-time NCAA champion UConn on December 11
The K-State women's basketball team will host the Connecticut Huskies on Sunday December 11, 2016, at 1:00 p.m. at Bramlage Coliseum.
Kyle Busch's crew chief suspended for lug nut violation
NASCAR has suspended Kyle Busch's crew chief and tire changer for one race for violating the lug nut policy during the team's win at Kansas …
Lorenzo Cain hits 3 HR's, Royals still fall to Yankees
The Kansas City Royals lost 10-7 to the New York Yankees on Tuesday night.
Seaman, Rossville, & Silver Lake baseball sweep doubleheaders; other scores
High school baseball, softball, and soccer scores from May 10, 2016.
MLB suspends Royals prospect Raul Mondesi Jr. 50 games
On Tuesday afternoon, the MLB suspended the Royals top prospect, Raul Mondesi Jr., 50 games for testing positive to performance enhancing dr…
Yankees hit five solo HR's, beat Royals in series-opener
The New York Yankees beat the Kansas City Royals 6-3 on Monday night at Yankee Stadium in New York.
Emporia State ready to make another run at MIAA Tournament
The regular season is over, and now the Emporia State baseball team has their eyes set on the MIAA Tournament.
Washburn Rural uses big 2nd half to beat Topeka High
Washburn Rural scored six second half goals on Monday night to beat Topeka High.
Oskaloosa softball sweeps Silver Lake; other scores
High school softball and baseball scores from May 9, 2016.
K-State's Britz signs with Buccaneers
Following an impressive tryout at rookie minicamp over the weekend, former Kansas State defensive tackle Travis Britz signed a free agent de…
Former HS standouts shine in NJCAA Regionals
Some former high school standouts were able to return to the place where they once shined.
Washburn swept by Central Missouri, falls to third in MIAA
No. 30 Washburn Baseball fell short in a 10-3 loss to No. 16 Central Missouri on Sunday, May 8 for Senior Day at Falley Field.
Royals drop series finale to Indians, have lost 4 straight series
CLEVELAND (AP) — Starter and stopper. Josh Tomlin is handling both roles for the Indians. The dependable right-hander stayed unbeaten and ag…


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Budget range low cost Live Entertainment to hire for weddings, corporate events and parties, the UK's largest entertainment agency, Alive Network.
Alternative for alivenetwork.com
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Great choice of cheap & affordable bands to hire for weddings, parties and corporate entertainment in the UK: Book Live Entertainment Agency.
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Red Hot Chili Peppers tribute band from Illinois. Includes member profiles, show dates, and sound files.
Alternative for funkymonksmusic.com
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Sabathia sublime in Yankees' win
BOSTON (AP) – CC Sabathia finally snapped out of his Red Sox funk, and it took an extra effort to do it.
The big Yankees left-hander struck out 10 on Tuesday night, throwing a season-high 128 pitches in six innings to beat Boston for the first time in five tries and lead New York to a 5-2 victory. The Yankees improved to 3-13 this season against the Red Sox, who still lead the AL East by one-half game.
"It's always a big game when you're playing the team you're chasing," Sabathia said, conceding to reporters that he had grown tired of the reminders of his struggles against Boston. "Of course, when you guys won't stop talking about it."
BLOG: Yankees' pitching, Red Sox MVP candidates in focus
BOX SCORE: Yankees 5, Red Sox 2
PHOTOS: The New York Yankees in pictures
Sabathia (18-7) had been 0-4 with a 7.20 ERA against the Red Sox this year, and 17-3 with a 2.40 ERA against the rest of baseball. He allowed two runs on 10 hits and two walks; only once in his career has he thrown more than 128 pitches.
USA TODAY Sports on Twitter!
To get the latest sports news from USA TODAY, including game results, columns and features, follow us on Twitter at @USATODAYSports.
"He got big outs when he had to, and that's CC," said Yankees manager Joe Girardi, who was ejected with one out to go after Mariano Rivera hit a swinging Jarrod Saltalamacchia with a pitch — the fourth hit batter of the game. "It's not like me to blow my top, but it's an important game. This is a huge game, a huge series."
Mariano Rivera finished the ninth for his 35th save.
John Lackey (12-10) allowed five runs — four earned — on seven hits and four walks, striking out three. Nick Swisher had three hits, and Francisco Cervelli hit a solo homer in the fifth, clapping as he crossed the plate. That may have been why, when he came up again in the seventh, Lackey hit him in the back, sparking a bench-clearing staredown.
"I totally understand how it could look that way. Guy hit a home run. Next at-bat, first pitch, you hit him," Saltalamacchia said. "We had no intent on hitting him. It just happened that way."
After getting hit, Cervelli moved toward the mound as the dugouts slowly emptied and home plate umpire Ed Rapuano tried to maintain order. There was nothing more than jawing back and forth, and in the end Yankees pitching coach Larry Rothschild was ejected.
In the first inning, Curtis Granderson took one off the end of the bat — or the hand, depending on whom you believe — and then Sabathia plunked Jacoby Ellsbury to lead off the bottom half.
"It's part of the game," Cervelli said. "Yankees-Boston, everybody wants to win."
New York took a 1-0 lead in the second and made it 3-0 in the fourth when Robinson Cano hit an RBI double and scored on Eric Chavez's single. After Boston cut the lead to 3-2 on Carl Crawford's homer and an RBI double by Marco Scutaro, New York added Cervelli's solo homer in the fifth and Derek Jeter's run-scoring double play in the seventh that made it 5-2.
The Red Sox had 13 hits in all, but Saltalamacchia stranded seven and Adrian Gonzalez stranded five; each struck out three times. It was also a rough day at the plate for Jorge Posada, who left five men on and grounded into a pair of double plays, and Jeter, who returned after missing two games with a bruised kneecap, grounded out five times.
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Pilonidal cyst
I am suffering from pilonidal cyst in my tail bone area between buttock for past 6 month, i have sitting job usually sit for 9hrs a day. I have redness and pus formation which usually discharge. I dont have aby pain. Please let me know how to cure it. I had consult with doctor who suggest me monocef o 200 and vizylac capsule but it doesn't heal.
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Doctor Answers (2) on Pilonidal cyst
Dr. Vimal Rastogi
14 yrs. of exp | Ghaziabad | Homeopath
Consult any classical homoeopath...soon it would be cured soon if action is taken early...lack of exercise and poor lifestyle is main cause of this...
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Madhur Nahal
21 yrs. of exp | Delhi | Homeopath
Homeopathy treats not only symptoms but also the cause by individualizing and patient's succeptibility.Please visit a homoeopath in person for its proper treatment.
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Skin Problem Daad
I having some skin infection between thighs . It keeps on itching. It is like some spots at the place. Daad I think we call it in Hindi. Also seems like some fungal . I have been applying Itch guard cream but can't see any positive effects. Please guide what to do. Any cream re commended or so? Thanks
205 Views
Doctor Answers (1) on Skin Problem Daad
Sharath Kumar K N
Mandya | General Physician
Hello sir,,, as you say 'it seems fungal and itching' it should give relief with ointment having antifungal and steroid combination, your itch guard will do that. Since it is not giving you results, kindly consult dermatologist get it diagnosed. Avoid tight undergarments.
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While buying a new Android smartphone, you must have found a feature in its specification sheet, named DLNA, alongside the Wi-Fi technical details. In most of the cases, users never understand what this feature is which result in never using of the same. But, if you want to stream content from your Android device to TV set, then it is possible because of the same technology.
Yes, DLNA can let you deal with the streaming and that's why you don't need any extra hardware to make things possible. I am sharing here are the best DLNA streaming apps for Android device. Since, DLNA hardware is already existing but it is lacking the software side, we need an application to complete the package.
Best DLNA Streaming Apps for Android
Technically, the TV set you want to stream media content, should be having the same DLNA technology included. Thankfully, every such TV set comes with the application require to drive those drivers. So, you select one of the below mentioned apps, install it on your Android smartphone or tablet, and get ready to do the online streaming for free.
Also, streaming any media content is pretty simple. Just open the media file you wish to stream, get your TV set ready for the connection, and hit the DLNA option, the app has newly installed on your device. It will start the content sharing instantly. Make sure both device and TV sets are at a working distance.
If you were looking for a premium application which comes without any price tag, then consider using AllCast. It works with almost every media streaming device like Amazon Fire TV, Chromecast, Apple TV, etc., and even supports Roku, Xbox 360, etc. In short, it covers almost every popular media streaming services along with any other DLNA render you may be using.
The app comes with very simple to understand, very easy to get addicted, and quickly learnable user interface which is going to help you throughout the time you want to use it. The only reason why you may want to look or alternative is that this free version comes with a limitation.
You can stream and watch pictures or videos of maximum 5 minutes at a time. But, to get complete access, you can always buy the premium or paid version, which is worth every penny. Try this free app and I am sure you will be interested in continuing with the same.


text:
Emelianenko-Mitrione bout postponed due to American's illnessSport February 19, 4:06
OSCE unable to identify perpetrators of cyber attacks against it - secretary generalWorld February 19, 4:02
Russian biathletes win gold in relay at 2017 IBU World Championships in AustriaSport February 18, 18:30
Putin signs decree on recognition of documents given to Donbass peopleRussian Politics & Diplomacy February 18, 17:26
Sberbank CEO says no repeat of crisis in the short termBusiness & Economy February 18, 17:24
Judging by certain statements at Munich Conference, "cold war" is still not over — LavrovRussian Politics & Diplomacy February 18, 15:19
Bout's lawyers will challenge Court of Appeals' decision in Supreme Court on February 21Russian Politics & Diplomacy February 18, 7:16
Turkish Minister reproaches NATO for not fulfilling obligations on its south-eastern flankWorld February 18, 7:12
Moody's upgrades outlook on Russia's sovereign rating to stable from negativeBusiness & Economy February 18, 2:37
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NOVO-OGAREVO, March 04. /ITAR-TASS/. No decision to revoke Russia's Ambassador to the US has been made yet, Russian President Vladimir Putin said in his countryside residence on Tuesday.


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tag:blogger.com,1999:blog-8777476886749761289.post3571841270906648148..comments2017-02-28T02:48:21.967+11:00Comments on baby space: 25 days of christmas : empire lane mobilesbron @ baby spacehttp://firstname.lastname@example.com:blogger.com,1999:blog-8777476886749761289.post-82077883430214648062016-09-30T19:28:11.566+10:002016-09-30T19:28:11.566+10:00Wow.. This is a lovely blog. I enjoyed going thro...Wow.. This is a lovely blog. I enjoyed going through it.. Really very nice.. It is very nice to see the cute little kids.. I appreciate the effort.. Loved it..

Assignment writing service reviews
Elizabeth Strattonhttp://firstname.lastname@example.com:blogger.com,1999:blog-8777476886749761289.post-17681647565433346362012-11-29T08:09:43.788+11:002012-11-29T08:09:43.788+11:00Lovely Bron, so simple, but so lovely. The cloud o...Lovely Bron, so simple, but so lovely. The cloud one is gorgeous! xAnna @ green tea n toasthttp://firstname.lastname@example.com:blogger.com,1999:blog-8777476886749761289.post-10553979075522830452012-11-28T12:43:43.079+11:002012-11-28T12:43:43.079+11:00Love the crane mobile. I should make one. I talk ...Love the crane mobile. I should make one. I talk as if I'm crafty, but I'm quite lazy...Chuzai Livinghttp://email@example.com:blogger.com,1999:blog-8777476886749761289.post-66103321955848775002012-11-28T08:28:07.120+11:002012-11-28T08:28:07.120+11:00Oh I adore these! I just went and had a look at E...Oh I adore these! I just went and had a look at Empire Lane's shop which was dangerous as there are so many gorgeous things there - I love the "Little Swallows" mobile in particular - it would go perfectly in my little one's nursery.

Just loving the Baby Space Christmas Gift Guide! So many unique and beautifully made products - I want to buy them all!!!! xxBhttp://email@example.com


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The use of imaging in the arena of primary treatment for breast cancer is gaining importance as a technique for assessing response to chemotherapy as well as assessing the underlying tumor biology. Both mammography and ultrasound have traditionally been used, in addition to clinical evaluation, to evaluate response to treatment although they have shed little light on the underlying biological processes. Functional magnetic resonance imaging techniques have the ability to assess response to treatments in addition to providing valuable information on changes in tumor perfusion, vascular permeability, oxygenation, cellularity, proliferation, and metabolism both at baseline and after treatment. This noninvasive method of evaluating cellular function is of importance both as endpoints for clinical trials and to our understanding of the biological mechanisms of cancer.
Imaging modalities have become increasingly valuable tools in the assessment of breast cancer, particularly in the arena of primary disease. They are used routinely in the diagnosis and assessment of breast cancer as well as in the evaluation of response to primary chemotherapy. These techniques have evolved over the past 30 or so years since they were introduced into routine practice and have significantly different roles compared with their original use as a diagnostic adjunct to clinical evaluations. They now play a role not only in screening and diagnosis but also in assessing operability and need for primary systemic therapy and assessing changes in response to treatment. As well as providing morphological assessments of breast cancer they can also give us insights into the biology and behavior of the disease leading to their classification as imaging biological markers.
These imaging biomarkers are of particular value in the early assessment of response to therapy which is of interest in identifying nonresponders early in their treatment journey and switching to potentially more effective therapy. The biological features that imaging and in particular magnetic resonance imaging (MRI), can provide information on are perfusion, oxygenation, vascularity, and cellularity (1). Imaging as a biomarker is noninvasive making it practical to be used for serial measurements, instead of repeat biopsies. Biological endpoints are also of potential utility in early stage clinical trials to evaluate novel treatments for further development (2) as they can address the potential mechanism of action of such treatments.
Neoadjuvant chemotherapy for breast cancer is used primarily for patients who have locally advanced disease that would not be amenable to breast conserving surgery in their current state. The intention of neoadjuvant chemotherapy is to allow breast conservation to take place whilst offering the other advantage of adjuvant chemotherapy, the treatment of micrometastatic disease. This setting provides a unique opportunity to use imaging biomarkers to assess tumor response to chemotherapy in comparison to pathological response to treatment. Pathological complete response (pCR) has been shown on meta-analysis to predict for relapse-free survival, disease-free survival, and overall survival (3). However, recent data has shown a variance of the ability of pCR to predict for outcome depending on histological parameters (4). Those with lower proliferating tumors including the luminal A and luminal B/HER2-positive groups displayed no prognostic benefit to pCR, whereas those with the more aggressive characteristics including the luminal B/HER2-negative, HER2-positive (nonluminal), and triple-negative tumors showed a significant prognostic impact of pCR. Despite this pCR still provides an excellent surrogate endpoint for higher risk patients and is also now used to accelerate drug approval in the United States (5).
In this review we will focus on what imaging can tell us about tumor biology and behavior at diagnosis and after neoadjuvant chemotherapy with specific reference to digital mammography, ultrasonography, and MRI.
Mammography has a well-established role in breast cancer management and most commonly in screening and diagnosis, but also in the assessment of response to therapy. Screen-film mammography has been considered to be the "gold standard" for many years although this is now being steadily replaced by "digital mammography" which allows easier storage of data as well as showing better rates of cancer detection in younger women, those with denser breast tissue, and women who are pre- and perimenopausal (6) as well as an equivalence to screen-film mammography for screening (7). Other advantages include a higher contrast resolution, a higher signal to noise ratio, and a slightly lower radiation dose although at the expense of lower spatial resolution (8).
The use of mammography for screening has been controversial although most studies have shown that there is a reduction in mortality. This may be at the cost of "overdiagnosis" (9,10). Features of breast cancer seen on mammography include a dense mass with a poorly defined border, a spiculate irregular mass, distortion of the breast tissue, asymmetric soft tissue, and specific formations of calcification including pleomorphism, linear and branching patterns, and fine clusters (11). However, mammography is very limited in the information it can provide about the underlying biology or behavior of breast cancer at the point of diagnosis. Newer mammographic techniques such as digital breast tomosynthesis, contrast-enhanced digital mammography, and dual energy mammography (spectral mammography) remain in development and their advantages over digital mammography are not yet proven (12).
Mammography has been used in the assessment of response to therapy in the breast after neoadjuvant chemotherapy to determine the extent of residual disease. As imaging techniques have changed with the advent of multimodality approaches most of these studies were performed more than 15 years ago. A study of 49 patients receiving Cyclophosphamide, Methotrexate, Fluorouracil (CMF) chemotherapy showed clinical examination predicted more responders than mammography (65.7% vs 54.3%) (13). A retrospective study looked at mammograms of 95 patients taken before and after neoadjuvant chemotherapy and found that five of the eight patients thought to have a complete pathological response actually had residual tumor and of the eight patients that actually had a complete pathological response only three were predicted by mammography (14). Another retrospective review reported 56 patients who received neoadjuvant chemotherapy and found that mammography had a better sensitivity than clinical examination for prediction of residual disease (79% vs 49%) but was less specific (77% vs 92%) (15). To our knowledge there have been no studies evaluating the routine use of mammography throughout a course of neoadjuvant chemotherapy to assess response, but instead is only performed at the end of chemotherapy, which reduces the utility in the earlier identification of nonresponders. However, there may be a role in the evaluation of disease progression during chemotherapy (16). Overall, mammography does not offer a great deal of information to the observer in terms of a morphological assessment of response, although it may complement other imaging methods and clinical examination in evaluating disease extent before surgery. It also has little to offer the observer in terms of assessment of tumor biology.
Ultrasound is a widely used technique for the imaging of primary breast cancer and axillary nodes. Unlike mammography, ultrasound does not have a routine role in screening for breast cancer but is used in particular for the characterization of the morphology of lesions as well as for image-guided interventions including biopsies. Breast cancers are typically solid on ultrasound, have irregular margins, and cast acoustic shadows distally (11). The use of ultrasound in addition to that of mammography has been shown to increase sensitivity (97% vs 74%) in the detection of primary breast cancer but also to have a false-positive rate of 2.4% (17).
In terms of the assessment of response to neoadjuvant therapy most studies have compared ultrasound to mammography, either on their own, or the utility of adding ultrasound to mammography for assessment of the primary lesion. A retrospective study of 100 patients found that ultrasound had a worse correlation with pathological outcome after neoadjuvant chemotherapy than physical examination or mammography. However, it was better correlated with lymph node response (18). Other studies have found that the accuracy of ultrasound is not significantly different to that of mammography (19) and its addition to mammography does not improve accuracy (20). A more recent review provided contradictory data showing that overall accuracy was greatest with ultrasound compared with clinical examination and mammography (21). A smaller study of 42 patients compared physical examination alone, a combination of mammography and ultrasound, and a combination of all three (22). The most accurate combination was found to be mammography and ultrasound although still with an accuracy rate of 67%. Doppler ultrasound has also been used to evaluate response assessment to chemotherapy for breast cancer. One study has found an increased sensitivity above clinical response for predicting pathological response after six cycles of chemotherapy (23) and a second study has found a similar outcome after three cycles of chemotherapy (24). The German Breast Group has made a similar observation in a study of 285 patients (25). They demonstrated that after two cycles of neoadjuvant chemotherapy (NAC), ultrasound assessment was more accurate than clinical examination in predicting nonresponding patients as well as patients who went on to have a pCR.
Newer ultrasound techniques are providing increasing information, in particular with regard to the underlying biology of breast cancers. Three-dimensional power Doppler ultrasound has been used to help classify breast lesions by identification of specific vascular features (26). It provides information on the underlying vascular network of larger vessels and this has application to the understanding of angiogenesis as well as being of value in the evaluation of antiangiogenic therapies. Another recent technical advance is the use of microbubble ultrasound which has been shown in selective series to increase the accuracy of diagnosis of primary breast lesions (27). Other novel techniques in ultrasound have attempted to improve diagnostic accuracy and interobserver variability include automated whole breast ultrasound, three-dimensional ultrasound, and sonoelastography (12). These techniques should still be regarded as experimental.
Overall with regard to ultrasound the data on the assessment of response of primary breast cancer to neoadjuvant therapy is mixed but does not seem to add significantly to the diagnostic accuracy of mammography and clinical examination. The studies seem to suffer from the same issues as those looking at mammography, namely only comparisons made at the end of chemotherapy, which does not aid response assessments during treatment. Explanations behind the failure of ultrasound to aid response assessments include the difficulty of posttreatment fibrosis. However, ultrasound is still used in routine practice for the assessment of response during chemotherapy and also has a role in the placement of tumor bed markers to guide surgeons in cases of good pathological response. Newer techniques promise to provide insights into the biology of tumors but have not yet been shown to aid our understanding of the changes in tumor behavior in response to chemotherapy.
Morphological MRI
MRI has an increasing role in the preoperative assessment of primary breast cancer. Its particular strengths include the imaging of mutifocal and multicentric disease, women with dense breasts, assessment of lobular carcinoma, post wide local excision with involved margins and patients presenting with involved axillary lymph nodes. MRI has also been shown to be of value in the assessment of breast cancer response to treatment. Most of the data to date has been using MRI to make anatomical assessment, in particular change in the size of tumors. The first significant study to address this question prospectively evaluated 39 patients pre– and post–neoadjuvant chemotherapy with a dedicated breast MRI and found that MRI predicted the pathological response in 97% of cases (28). This accuracy was far superior to that of mammography or clinical examination. Other studies that have compared the accuracy of differing modalities in predicting for response have shown both MRI and mammography to be superior to ultrasound and clinical examination (89%, 89%, 82%, and 75%, respectively) (19). Yi et al. (29) reviewed the MRI scans of 187 women who had received six cycles of NAC and found that a smaller reduction in tumor volume was an independent predictor of worse recurrence-free and overall survival. A short meta-analysis, which did not include the data of Yi, of between 230 and 301 patients across the modalities has been recently performed. The results from this study are summarized below (Table 1) (21). Overall the data shows that MRI as a single modality had the best accuracy, positive predictive value, and negative predictive value. It is however second to ultrasound in its sensitivity and second to clinical examination in its specificity.
|Clinical examination
|Digital mammography
|Positive predictive value
|Negative predictive value
|Clinical examination
|Digital mammography
|Positive predictive value
|Negative predictive value
*MRI = magnetic resonance imaging.
MRI is mainly used in assessing response to therapy using an anatomical approach. However the use of functional MRI has increased, mainly in clinical trial settings, and this can add a substantial amount of information to more traditional morphologic approaches. Functional MRI can also be known as quantitative MRI as it is able to measure intrinsic tissue properties, and using an appropriate model, compute these to provide numerical outcomes (30).
Dynamic Contrast-Enhanced MRI
Dynamic contrast-enhanced MRI is one commonly used functional MRI technique. This allows the detection of changes in T1 relaxation times caused by the passage of a gadolinium-based contrast agent through the tissue being studied. Multiple images are taken through the time course of contrast injection and uptake signal changes allow the computation of parameters such as Ktrans which is the contrast transfer rate constant showing blood vessel perfusion and permeability, ve which is the extravascular, extracellular volume fraction, and vp which is the plasma volume fraction (30) (Figure 1).
There are a number of studies that have used dynamic contrast-enhanced-MRI to assess response to neoadjuvant chemotherapy. We have previously shown that changes in kinetic dynamic contrast-enhanced-MRI parameters and Ktrans in particular can predict for both clinical and pathological response, where change in tumor size was not predictive (31). We subsequently reported that posttreatment Ktrans was also predictive of overall survival (32). A recent study has demonstrated that, after six cycles of NAC, a smaller reduction in the washout component was associated with worse disease-free and overall survival (29), a finding consistent with our data. A systematic review was conducted by Marinovich et al. (33) which identified 13 studies looking at dynamic contrast-enhanced-MRI in assessment of pathological response to NAC in breast cancer. The results were difficult to interpret mainly due to the heterogeneity of the studies involved but suggested that tumor volume, Ktrans, and early contrast uptake showed the highest sensitivity and specificity for prediction of pathological response. The biological basis for these changes and in particular those of Ktrans are not entirely understood. However, it is likely to relate to the changes within the microvasculature due to withdrawal of tissue vascular endothelial growth factor levels as a result of tumor cell death leading to endothelial cell apoptosis and a reduction in the proportion of proliferating blood vessels (31). The direct effect of chemotherapy on proliferating endothelial cells is considered to be a minor effect.
Blood Oxygen Level–Dependent MRI
Another biological process that MRI has a role in assessing in primary breast cancer is blood oxygenation and flow using blood oxygen level–dependent MRI. This technique uses the paramagnetic properties of deoxyhemoglobin, creating variations in the magnetic field, and reducing the relaxation rate (R2*) of water in blood and surrounding tissues. Hypoxia will therefore lead to an increased deoxyhemoglobin and a faster R2* (34). This technique has mainly been used in neuroradiology but also in cancer and specifically breast cancer. In a study of 31 patients with breast cancer treated with NAC we found increases in R2* after two cycles of treatment, with greater changes in those who went on to achieve a pathological response (32). However, this was not as useful as Ktrans in predicting a response. The likely hypothesis for increased R2* in response to chemotherapy is an increase in tumor hypoxia, although the data for this is mainly drawn from animal xenograft models.
Diffusion-Weighted MRI
Diffusion-weighted MRI is a functional imaging technique that can be used to measure water diffusivity and does not require the use of contrast agents. Modified fat-suppressed T2-weighted spin-echo sequences are used and the application of diffusion-sensitizing gradients with differing amplitudes allows the calculation of water diffusivity, often called the apparent diffusion coefficient (ADC) (35). The ADC value depends on the freedom of movement of water at the cellular level allowing the differentiation of benign and malignant tissues. Within cancers the diffusion of water can also be affected by the cell density with an increased proliferation leading to an increase in the "packing" of cells thereby reducing the freedom of water and the ADC (30). Of particular interest is the ability for this technique to pick up changes in ADC in response to therapy. As tumor cells die, a process of cell death and apoptosis causes rupture of cell membranes increasing water diffusivity and ADC.
Most of the work using diffusion-weighted MRI in primary breast cancer has focused on the differentiation of benign and malignant lesions. These studies have found a significant difference in the ADC value between differing types of tissue as well as difference associated with cellularity within malignant lesions (36). This technique has been used to assess response to therapy after neoadjuvant chemotherapy. Two small studies from the same group found conflicting results with regard to ADC changes, one with 10 patients showing significant changes after the first and second cycle (37) and the other with 16 patients showing that ADC did not display an early response (38). However, this second study did show that early changes in fat:water ratios and water T2 could be used to predict a final tumor volume response. A third study with 11 patients demonstrated that ADC was particularly sensitive to changes in tumor status (39). These findings have been corroborated by a much larger study with 56 participants with locally advanced cancers and 25 nonmalignant controls (40). This study showed that ADC was more useful than typical morphological changes on MRI at predicting tumor response. This finding is consistent with two of the three earlier and smaller studies.
MR Spectroscopy
MR spectroscopy uses the behavior of hydrogen (1H) to demonstrate metabolic changes in cancer cells, in particular using molecules such as choline that are known to be elevated in malignant tissues. MR spectroscopy can detect these elevated levels to increase the specificity of a malignant diagnosis. Tozaki et al. (41) have assessed it in the setting of response to neoadjuvant therapy. A study of 16 patients found an improved ability to predict pathological responders by reductions in the choline signal after two cycles of NAC in breast cancer. A second study by the same authors (42) looked at seven cases of breast cancer after one cycle of NAC and found a correlation between the change in choline signal and the change in lesion size. The same correlation was not observed between a change in ADC using diffusion-weighted MRI and a change in size. These studies suggest that the normalization of these high concentrations of tumor metabolites is associated with a response to treatment, perhaps because of reduced cellular activity or burden of disease after treatment.
Additional Approaches
Other MRI approaches are in development including MR elastography, which assesses tissue stiffness, although has not yet been used to assess response to primary therapy. Other non-MRI functional imaging techniques include positron emission tomography, which uses a radiotracer, most commonly [18F]2-fluoro-2-d-glucose, to assess tumor activity. This approach been used to demonstrate that [18F]2-fluoro-2-d-glucose reduction after a single cycle of NAC is predictive of a pathological response to treatment (43), and at least 10 other studies reviewed by Groheux et al. (44) have addressed this question, showing a correlation between early changes in the SUVmax and final pathological response. The other positron emission tomography tracer of particular interest is [18F]fluorothymidine which is a potential biomarker of proliferation. [18F]fluorothymidine-positron emission tomography uptake has been shown to be well correlated in breast cancer with the gold standard marker of proliferation, Ki-67 by immunohistochemistry (45), and reduction in [18F]fluorothymidine uptake after chemotherapy has been demonstrated to predict clinical response (46). Perfusion computed tomography has also been studied in breast cancer and found to be of utility in predicting response to NAC (47). It uses changes in tissue attenuation after administration of contrast media to allow the modeling (48) of kinetic parameters including changes in blood flow, blood volumes, and permeability, which are characteristics of tumor angiogenesis and therefore of potential value in the assessment of antiangiogenic therapies.
Mammography, ultrasound, and morphological MRI play essential everyday roles in the management of breast cancer. In the setting of NAC they have been shown to increase the accuracy of response prediction in comparison to clinical examinations. However, once one moves beyond morphological assessment to a biological approach to tumor imaging their utility is limited. Functional MRI approaches can reveal the underlying biological processes both before treatment and after chemotherapy, shedding new light on the pathophysiological nature of breast cancer in a noninvasive way, and without the use of ionizing radiation. These techniques allow us to assess cellularity, vascularity, oxygenation, and metabolism of tumors. They also provide the potential to act as clinical trial endpoints in the era of biological-targeted therapies although further work to validate these approaches is required.
We acknowledge the Breast Cancer Campaign and the Breast Cancer Research Trust who providing funding for our work.
- magnetic resonance imaging
- ultrasonography
- metabolism
- alveolar ventilation function
- cancer
- cell function
- chemotherapy regimen
- mammography
- perfusion
- diagnostic imaging
- neoplasms
- cell respiration
- breast cancer
- functional magnetic resonance imaging
- mammography, digital
- surrogate endpoints
- vascular permeability


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In The Spotlight
Sunday 19 January saw Cashandra Slingerland take on the Ride for Sight 116km Classic with her Cycle Nation Women's Team starting at the Boksburg Stadium.
Images from the Dis-Chem Ride for Sight held in Boksburg.
Images from day 6 of the South African National Championships held in Wellington.
Images from day 5 of the South African Road Championships held in Wellington.
In a world first for sporting events, the Absa Cape Epic will include a mountain biker riding with the pro peloton who will deliver 360-degree immersive video during the 8-day stage race when it takes place in the Western Cape in March 2016.
The Cervélo Bigla Pro Cycling Team is proud to announce a partnership with gebioMized. The biomechanic company with a focus on dynamic bike fit technology sent a team from Germany made up of sports scientists out to the team's training camp in Mallorca to work on bike positioning with the riders, looking for the optimal bike fit through different touch points such as the saddle and shoes.
"It's a great honour for us to work with such a professional team. Women's cycling is increasing and improving the level of professionalism and we are absolutely proud to be part of that," Lotte Kraus of gebioMized said.
Speaking more about the technology, Kraus continued: "We are working with dynamic pressure mats at the contact points. They are flexible so that they can perfectly adapt on the saddle and we are analyzing the interaction of the pelvic anatomy to figure out if the saddle is positioned perfectly, if the sitting position is optimal and if we can change anything, either the saddle position or padding of the bib shorts. This is to guarantee riding in a comfortable position and so the athletes can produce the maximum power output on the bike."
gebioMized works closely with Endura, the team's new clothing partner. An example of the collaboration sees software which analyses the athlete's touch points in the bib shorts, choosing the perfect padding on an individual basis. Inner soles are also examined and moulded to fit perfectly within the shoe.


text: Hello, friends, I wanted to ask for your perspective on an issue that's hitting our church. We have co-ed classes that are team taught by married couples in Sunday School. Many of our classes are all one gender, but a few are co-ed. Some of our deacons all of a sudden are now making a big fuss about the situation, and have brought it up to the deacon body. Now, the pastor and the entire staff (of which I am a part) are in agreement: As long as the woman is teaching under her husband's authority (and the authority of the pastor), there is no problem. That was clearly given to the deacons. But this was not good enough for the band of three who are causing the fuss. The deacons have called a special meeting to vote on this issue tomorrow. Now, here's a question: Are the deacons going outside of their Scriptural responsibilities in usurping the pastor's authority? While we could argue on the Biblical evidence of women teaching/not teaching, this isn't the place. That's another issue all together that our staff has prayed over, searched the Scripture, and decided upon. I guess I'm wondering if any pastors or other staff members have had to deal with a deacon body run amuck...how did you handle this? The entire ministerial staff (11 of us) will be there to support our pastor tomorrow. Many of the deacons have spoken out in favor of the staff. To be honest, if the pastor gives in to these three men (and whatever support they may have gotten during this week), not only I, but over half of our staff, have stated that we will turn in our resignation letters over this. Am I overreacting? Thoughts?


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Franklin is located in Norfolk county and has a population of 29,560.
Small Business schools in Franklin charged students an average tuition of $28,020.00 if they were Massachusetts residents, and $28,020.00 if they were non-residents, during the 2009 - 2010 school year.
The average cost of books and supplies for small business schools in Franklin is $1,000.00. Students who live on campus while attending a small business school in Franklin, can expect to pay an average of $11,964.00 for room and board. Students who live at home can expect average costs to be $1,200.00. There is one small business college in Franklin for students to choose from. Small Business programs in Franklin reportedly graduated 35 students in the 2008 - 2009 school year.
|Average Salary
|Number Employed in City
|General and Operations Managers


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Human Resource Management in Developing Countries
Edited by Pawan S. Budhwar Yaw A. Debrah
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Human Resource Management in Developing Countries by Pawan S. Budhwar
Book DescriptionFocusing on HRM developments in thirteen developing countries across Asia, Africa and the Middle East, this book explores the contextual functions of HR in these countries. In addition, it analyzes the more general issues of HRM in cross-national settings to give readers an understanding of HR that is both comparative and contextual. Covering the policies and practices of China, South Korea, Taiwan, India, Nepal, Pakistan, Iran, Saudi Arabia, Algeria, Nigeria, Ghana, Kenya and South Africa, each chapter follows a framework that draws out all of the unique and diverse configurations of HRM. This important text is an invaluable resource for all HRM practitioners, students and scholars of HRM, international HRM and international business.
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Book DetailsISBN: 9780415223331
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Publisher: Taylor & Francis Ltd
Publish Date: 10-May-2001
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A comprehensive introduction to HRM for students who are new to the field, but who will be seeking employment in a global market, working with diverse colleagues and across international borders.
Emerging Indian Multinationals, Hardback (July 2016)
Based on comparative data and interviews with over 90 senior managerial personnel from Indian multinationals, this book provides a comprehensive picture of the emerging multinational firms from India in terms of their internationalization process, competitive advantages, approach to global markets, and future outlook.
Human Resource Management, Innovation and Performance, Hardback (November 2015)View all books by Pawan S. Budhwar
Human Resource Management, Innovation and Performance investigates the relationship between HRM, innovation and performance. Taking a multi-level perspective the book reflects critically on contentious themes such as high performance work systems, organizational design options, cross-boundary working, leadership styles and learning at work.
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Here's all the hot Hollywood gossip including Blake Lively's premonition, Shia leBeouf's mentor of a director, Eva Mendes' adorable preference, Paris Hilton's line of hotels and Brooklyn Decker's special contribution to the Special Olympics.
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Winterton Reviews
Winterton / Central Berg
There really is so much to do in the Winterton / Central Berg area so try not to waste a day!If you don't already have the run-down on 'what to do', then stop at one of the local restaurants or curio shops on arrival and grab a handful of brochures. Then plan your holiday activities from there.
South Africa
South Africa
Lifes amazing wonders!
Winterton is just not a town, but a region with its own culture. A little like the winelands in the Cape. There are the magnificent Drakensburg mountains as a backdrop to a plethora of other interests in the area. The Winterton area is steeped in South African History for the buffs that want to see the battles that occurred during the Boer/English/Zulu wars. There is also the magnificent Drakensburg Escarpment that carries its own history of the SAN people. The area is a National Heritage site and a sanctuary for many protected birds of prey. In addition to all of this, the Winterton...see more
Kim Donaldson
South Africa
South Africa
Winterton Accommodation
If you are looking for Winterton holiday accommodation , SafariNow has a selection of Self-catering, Bed and Breakfast, Holiday Home holiday accommodation in Winterton and surrounds. With 15 listings in Winterton, our handy Winterton map search and great low prices, it's easy to book the perfect holiday accommodation for your Winterton visit.)


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- Affiliations:
1 National Institute of Aquatic Resources, Technical University of Denmark
2 Section for Ecosystem based Marine Management, National Institute of Aquatic Resources, Technical University of Denmark
3 French Research Institute for the Exploitation of the Sea
4 Wageningen IMARES
- 10.1080/23308249.2014.899557
- Abstract:
- Many marine fish stocks are overexploited and considerable overcapacity exists in fishing fleets worldwide. One of the reasons for the imbalance between resource availability and fishing capacity is technological development, which continuously increases the efficiency of the vessels—a mechanism referred to as "technological creep." We review how the introduction of new and more efficient electronic equipment, gear design, engines, deck equipment, and catch-handling procedures influences the capture efficiency (catchability) of commercial fishing vessels. On average, we estimate that catchability increases by 3.2% per year due to technological developments, an increase often ignored in fisheries management. The documentation and quantification of technological creep improves the basis for successfully integrating the effects of technological development (and catchability changes) in fisheries management regulations and policies. Ways of counteracting the undesired effects of technological creep are discussed as are the potential management benefits from improved fishing technology. Specific suggestions are given on the selection, application, and tuning of fisheries management tools that can be used to improve the balance between harvesting capacity and resource availability
- Type:
- Journal article
- Language:
- English
- Published in:
- Reviews in Fisheries Science, 2014, Vol 22, Issue 2, p. 156-174
- Main Research Area:
- Science/technology
- Publication Status:
- Published
- Review type:
- Peer Review
- Submission year:
- 2014
- Scientific Level:
- Scientific
- 267774591


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John and Iva are a American Saddlebred team. BLACK AND MATCH REALLY WELL BOTH ARE 15.1 HANDS John is 7 and Iva is 12. Raised here in Ky by one of my friends…SOLD
I am offering this ASB mare, very reasonably, to an amazing new home. She is registered with incredible show bloodlines. Very sweet, sound in all ways…SOLD
Mary is a 8 year old american saddle bred mare . Safe for anyone to ride and drive. drives single or double traffic safe Also worked in field w machinery…SOLD
Has done it all. Gaming, breed shows, trail rides, parades, jumping, dressage, you name it! - Incredibly willing to try new things - Very sweet temperament…SOLD
Very gentle gaited mare. Great for kids, trail riding or hunting. Can provide video of her being shot off of. Call Jason at 601-218-9628SOLD
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Well behaved, accustomed to children. Energetic and always up for adventures. He loves the trails. Good polocrosse prospect. He was a rescue, and due…SOLD
Fred is a 10 year old registered American Saddlebred gelding. He has done it all! Saddleseat, huntseat, western pleasure (doesnt fully neck rein yet),…SOLD


text:
WLI-UTX-AG300 print
Router infoOpenWrt supported: no
dd-wrt supported: no
Flash: n/a
WiFi: 300mbps (abgn)
WAN-speed: N/A ()
ETH-ports (LAN): 1
ETH-speed: 100mbps (10/100)
USB-ports: no
Hard reset instructions for Buffalo WLI-UTX-AG300
With the reset button
- Have the router plugged in and powered on
- Press and hold the reset button for 10 seconds until DIAG led start shining red
- Wait for DIAG led to turn off again.
The 30-30-30 resetIf the above instructions don't work you can always try the 30-30-30 reset as follows:
- When router is powered on, press the reset button and hold for 30 seconds. (Use a paper clip or something sharp)
- While holding the reset button pressed, unplug the power of the router and hold the reset button for 30 seconds
- While still holding the reset button down, turn on the power to the unit again and hold for another 30 seconds.
Default factory settings for Buffalo WLI-UTX-AG300
Default admin username: admin
Default admin password: password
Default subnet mask: 255.255.255.0
Default DNS server: 188.8.131.52
User Manuals for WLI-UTX-AG300
|save User Manual (click to download)
|Feb. 22, 2012


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Welcome to our villa. We are native Puertorricans who have been living in the Lone Star State for over 30 years. Now that our children are grown and with families of their own, we decided to purchase this property to ensure that our grandchildren (all of them US born) have a place where they can connect with their latin roots.
We hope that we can share our little corner of paradise with you. Don't hesitate to contact us with any questions.


text:
Italy trip is planned for March (last week). Woohoo!!!
I arrive in Venice then travel via train to Florence and then train to Rome before we fly home.
Looking for tips on what to pack and what the weather may be like at this time. I like to be comfortable for walking but love fashion as well. Recommended shoes? Should I bring rain boots?
Thank you.
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Italy weather last week of March.
Italy trip is planned for March (last week). Woohoo!!!
Report Abuse
The link above gives the weather for Rome. You can plug in other cities as needed.
It's awfully hard to predict what the weather is going to be in a certain week several months into the future. (I realize there are places in the world where the weather at a certain time of year is consistent day to day, but I don't think you're going to one of those places.)
For instance, in Rome, the average temp for March is about 55. You'll get days lower and higher. The average number of rainy days is about 10. Will they come the days you're there. I dunno.
Report Abuse
The Italians will wear their winter attire - American tourists will wear shorts and make ridiculous figures with their goosebumps.
Earnestly, it will be pretty chilly, especially in Venice. If you are lucky, you catch a few sunny days in Florence or Rome. You may wear short sleeves when you will be sitting outside for lunch, but the evenings will be chilly.
So, take some warm things and dress in layers. Taking raingear is always a good idea.
You need shoes which are comfortable for walking long distances over cobblestone pavements.
Report Abuse
This is something you might be thinking about 3 days before you leave, not 10 months.
I don't ever take rain boots anywhere. I wear them at home in the garden, would never think of traveling with them.
Report Abuse
I just googled "rain boots" - OMG, these are Wellingtons!
Never, ever walk with these through elegant cities like Florence, Rome of Venice! These are cities, not swamps!
Report Abuse
We were in Italy a few weeks ago--Umbria and Rome--and encountered weather substantially cooler and wetter than at the same time last year during another visit. We were told that this past March was unseasonably hot. Averages will only give you a vague sense of what to bring. Just keep an eye on the weather a few days out and pack accordingly.
Report Abuse
The "few days out" advice is the best.
Report Abuse
StCirq - I thought this was a forum I could ask questions about traveling and planning my trip which includes what the weather may be like. I know I won't know ubtil it gets closer obviously but I wanted to ask for those who have traveled during this time what their experience has been.
@ traveller1959/As far as rain boots. I have a pair of packable Hunter boots that are very comfortable and stylish. The reason I asked was because I have read on a few blogs that women have taken these same boots on trips to Europe.
Report Abuse
Hunters are ok in Europe, they are a common sight in upscale neighbourhoods in cities with big parks. At times Hunters make perfect sense.
Acqua alta happens mostly in October-February. November is by far the worst month, but you may get some instances of acqua alta in March so it may make sense to take the Hunters. I passed Venice's airport twice this March and both times it was raining heavily and the wind was terrible. But acqua alta is not that bad, I have some incredible pictures of lights reflected on the water at San Marco and the city seemed very well prepared for it. I love Venice in the winter.
My favourite shoes for walking are Hogan's Interactive. You'll see tons of Italians wearing those, they are incredibly comfortable and perfect for cobblestones. I find them a lot more comfortable than Hunters.
Report Abuse
In March, I would always be prepared with layers I can put on or take off. Even a day that starts out chilly can get quite warm by mid-day. I would also carry a small day pack to put the layers in when you peel them off.
Acqua Alta is caused by tides and winds, not by rain. It only lasts a few hours. If it happens, you can buy cheap rubber boots or just wait it out. There will be wooden walkways put out in a lot of the center. Nothing stylish will be suitable for walking through acqua alta.
Report Abuse
For Italy late March I bring ankle high leather boots. Not sufficient for acqua alta but as stated above, you can buy cheap rubber boots or these disposable plastic boot things. But for other than that you want something that will keep your feet dry if it's raining, for the most part you won't be walking through high water.
You could expect some days will be quite warm in the middle of the day, so a few short sleeve tops, with layers of sweaters and a rain coat/jacket. I worn jeans every day of my last March Italy trip, which included two weeks of temps ranging from evening lows of about 32F to some day time highs in the low 70s.
Report Abuse
>>StCirq - I thought this was a forum I could ask questions about traveling and planning my trip which includes what the weather may be like. I know I won't know ubtil it gets closer obviously but I wanted to ask for those who have traveled during this time what their experience has been. <<
Unfortunately their 'experience' won't help you one whit.
If you were asking about August . . . most likely hot and muggy, January most likely damp w/ some rain.
But in March you could in fact have absolutely anything.
See indyhiker's post -- same time one year apart and totally different weather.
The suggestion to wait until 3 or 4 days out is the best advice you've received.
Sign in to comment.


text:
The Daily Froth: June 25 {Pancake Edition}
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All your favorite dinosaurs are wrong. Today's Big Thing


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For many caregivers, memory care communities signal the end of something, but it doesn't have to be seen that way. Modern memory care communities are structured to help seniors with memory loss retain their memory and independence with their specialized care, nutritious meals, social activities and more.
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Welcome to RD Electrical
Part P and N.I.C registered, I am a fully qualified electrician in domestic-industrial and commercial electrical works I pride myself on being professional and reliable and to carry out all your electrical needs efficiently.Please call anytime for a free estimate.
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Elvis presley christmas
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This week's Christmas album is a playlist of the one and only king of rock n' roll, Elvis Presley.
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Studies in Television
By (author) John Hartley
Format: Hardback
Normal Price: $188.00
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Tele-ology by John Hartley
Book DescriptionTeleology brings together John Hartley's work on television. The book draws on current critical theory in cultural studies to develop a wide-ranging and thought-provoking view of television broadcasting in Britain, Australia and the USA. Neighbours, Hancock's Half Hour, Dallas, Monty Python, Miami Vice, Beverly Hillbillies and Bonanza are among the examples of TV art that are discussed in Hartley's exploration of cultural politics. He takes in TV truth and propaganda; populism in the news; mythologies of the audience; TV drama as a 'photopoetic' genre in the tradition of Shakespeare; Kylie Minogue, Madonna and gardening shows.
Buy Tele-ology book by John Hartley from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780415068178
(234mm x 156mm x mm)
Pages: 256
Imprint: Routledge
Publisher: Taylor & Francis Ltd
Publish Date: 2-Apr-1992
Country of Publication: United Kingdom
Other Editions...
Books By Author John Hartley
6th Battalion the Cheshire Regiment in the Great War, Hardback (June 2017)
The story is told from the Battalion s formation in 1908 to its disbandment in the 1920s
Cultural Science, Paperback (March 2016)
Cultural Science is a new way of thinking about culture. The book synthesises recent work across different disciplines, setting out a new, evolutionary approach to cultural studies. Engaging with scientific traditions in a way that previous literature has failed to do, it promises to be break new ground in social scientific scholarship.
Creative Economy and Culture, Paperback (September 2015)
An authoritative exploration of the current state of the creative industries, showing how students, researchers, entrepreneurs, practitioners and policy makers can make use of recent advances in the systematic study of the creative process on a population-wide scale.
Companion to New Media Dynamics, Paperback (May 2015)» View all books by John Hartley
As the lines have grown blurred between 'new' and 'traditional' media forms, there is much to learn about the dynamics surrounding the growth and adoption of new media.
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List of the world's Top 10 most expensive clothing brands 2016
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