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Watson Announces Positive Data for Its Investigational Oxybutynin Topical Gel for the Treatment of Overactive Bladder at SUNA's Annual Conference
Previously, the efficacy and safety of OTG were demonstrated in a Phase 3multi-center, double blind, placebo-controlled study. The study showed thatdaily treatment of a 1g dose of OTG for 12 weeks was superior to placebo atrelieving OAB symptoms, based on patient urinary diaries, which demonstrated areduction in incontinence episodes and urinary frequency, and an increase invoid volume. Secondary endpoints indicated a significant positive effect ofOTG treatment on quality-of-life. Treatment was well tolerated in the studywith no treatment-related serious adverse events.
"A topical oxybutynin gel is a convenient option for treating OAB that iseasy to use and offers a way to improve treatment compliance among patients,"said Diane K. Newman, RNC, MSN, CRNP, FAAM, lead author and Co-Director of thePenn Center for Continence and Pelvic Health, Division of Urology, Universityof Pennsylvania. "Transdermal drug delivery through a topical gel is a widelyaccepted and effective technology in urology. Our data confirm that thisparticular gel can fit nicely into a busy woman's daily regimen, includingshowering and sunscreen use, without compromising efficacy."
Clinical Data Presented at SUNA
The data presented at the Society of Urologic Nurses and Associates (SUNA)Annual Conference are from three open-label, randomized studies in healthy menand women which showed that showering one hour or later, or the application ofsunscreen 30 minutes before or after OTG application did not significantlyalter the absorption and systemic blood levels of OTG. The data also foundlimited transference of the drug when treated people came into contact withtheir untreated partner.
The new abstract included data from three open-label, randomized studiesconducted in healthy men and women. In the showering study, participantsreceived OTG for 35 days. Every seven days, starting at day 14, subjectseither didn't shower or showered at 1, 2, or 6 hours after dosing. At the timepoints tested, showering did not have a meaningful impact on delivery of thedrug into the bloodstream.
In the sunscreen study, participants received OTG alone, or 30 minutesbefore or after applying sunscreen. All three application regimens resultedin similar oxybutynin absorption and time to maximum blood plasmaconcentration (Tmax).
In these studies, OTG demonstrated good safety and tolerability. Notreatment-related adverse events were observed, and no skin reactions to thegel application site were exhibited. In addition, there were no significantchanges in vital signs among any of the trial participants between pre- andpost-study evaluations.
"We are very excited about the new data, which further point to theoutstanding convenience and ease-of-use of OTG, our topical gel formulation ofoxybutynin, for patients suffering from OAB," said Edward Heimers, Jr.,Executive Vice President and President of Watson's Brand division. "Throughproducts like OTG, Watson continues to work to meet the highest standards ofsafety and efficacy while offering novel treatment solutions that allowpatients to focus on enjoying their lives."
About Oxybutynin Topical Gel (OTG)
OTG is a clear, rapid-drying, odorless formulation of oxybutyninhydrochloride that is under development for the treatment of OAB with symptomsof urge urinary incontinence, urgency and frequency. It is designed todeliver a consistent dose of oxybutynin through the skin over a 24-hour periodto help decrease urinary urgency and the frequency of incontinence episodes inpatients with OAB. A one-gram (approx. 1 mL) dose of 100mg/g OTG, applied oncedaily, delivers about 4mg oxybutynin each day.
About Watson Pharmaceuticals, Inc.
Watson Pharmaceuticals, Inc. is a leading specialty pharmaceutical companythat develops, manufactures, markets, sells and distributes generic andspecialty brand pharmaceutical products. Watson pursues a growth strategycombining internal product development, strategic alliances and collaborationsand synergistic acquisitions of products and businesses.
The mission of Watson Urology is to offer products and services thatimprove the quality of patients' lives, and satisfy the needs of physicianswho specialize in the diagnosis, management, and treatment of urologicaldisorders. By advancing education and support for urological diseases, we arecreating the differences that make life more livable.
In the U.S., the Watson Urology portfolio includes: Oxytrol(R);TRELSTAR(R) LA; TRELSTAR(R) Depot; Androderm(R); ProQuin(R) XR, under aco-promotion agreement with Depomed, Inc.; and AndroGel(R), under a co-promotion agreement with Solvay Pharmaceuticals, Inc. In addition tooxybutynin topical gel, the Watson portfolio includes a number of productsunder development including: Rapaflo(TM)(silodosin), a product for thetreatment of benign prostatic hyperplasia; and a six-month formulation ofTRELSTAR(R) (triptorelin pamoate for injectable suspension), for the treatmentof advanced prostate cancer and Uracyst(TM), for cystitis.
For press releases and other company information, visit WatsonPharmaceuticals' Web site at http://www.watson.com.
Forward-Looking Statement
Any statements contained in this press release that refer to future eventsor other non-historical facts are forward-looking statements that reflectWatson's current perspective of existing trends and information as of the dateof this release. Except as expressly required by law, Watson disclaims anyintent or obligation to update these forward-looking statements. Actualresults may differ materially from Watson's current expectations dependingupon a number of factors affecting Watson's business. These factors include,among others, the difficulty of predicting the timing or outcome of productdevelopment efforts and FDA or other regulatory agency approvals or actions,if any; whether the results of clinical trials for oxybutynin topical gel andother information will be sufficient to support approval by FDA or otherregulatory authorities; patents and other intellectual property rights held bythe Company and the ability to successfully enforce such rights against thirdparties; the impact of competitive products and pricing; market acceptance ofand continued demand for Watson's products; difficulties or delays inmanufacturing; and other risks and uncertainties detailed in Watson's periodicpublic filings with the Securities and Exchange Commission, including but notlimited to Watson's Annual Report on Form 10-K for the year ended December 31,2007.
(Logo: http://www.newscom.com/cgi-bin/prnh/20020214/WATSONLOGO)
SOURCE Watson Pharmaceuticals, Inc.
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CLOSED: SkyeCabo
16 de Septiembre, Colonia Centro, Cabo San Lucas, Mexico, 23473
Serves meat, vegan options available. Restaurant offering a varied menu of food, baked goods, and juices, including vegetarian as well organic choices. Has Wi-Fi and air conditioning. Confirmed closed January 2017.
Category: Lacto, Ovo, Organic, Western, Juice bar, Mexican, Bakery, Non-veg
Reviews (1)First Review by unoclay
Good, simple mexican food - Edit
We stopped here during the quiet early September (decidedly low tourist attendance) season and had the small restaurant-kitchenette to ourselves. Food was straightforward and good--nothing flashy, but healthy without a doubt, and did the job. We had guac, salsa, chips, and two taco/fajitta dishes, one with some sort of cactus (a good, smokey/sweet flavor?) and another simpler beans-corn-etc dish. Service was very slow, but we werent in a hurry--took about 20 min for chips/fresh salsa/guac, and another 20+ for our main dishes. It was as though they made everything fresh upon our arrival--perhaps due to a slow day. We didnt mind, but it wasnt speedy. Limited english spoken, but we were able to make ourselves understood with limited spanish and gestures. Recommended, if you're in the mood for healthy, simple food.
Pros: healthy, simple, straighforward mexican authentic, reasonably cheap
Cons: somewhat slow service, small place
Link to this page from your site.
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subset: commoncrawl


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Get an overview of this hotelInn in Lima with free breakfast and rooftop terrace
Situated in Lima, this inn is within 1 mi (2 km) of Archaeological Site of Mateo Salado, Larco Herrera Museum, and Pontifical Catholic University of Peru. Plaza Bolivar and National Museum of the Archaeology Anthropology and History of Peru are also within 2 mi (3 km).
Property Features
Along with a rooftop terrace, this inn has coffee/tea in a common area and laundry facilities. Free continental breakfast and free WiFi in public areas are also provided.
Room Amenities
Rooms offer cable TV and desks.Information missing or incorrect? Tell us!Opens in a new window
Posada Peregrinus
Property Amenities
Property Amenities
A complimentary breakfast is offered each morning. Public areas are equipped with complimentary high-speed wireless Internet access. For a surcharge, a roundtrip airport shuttle (available 24 hours) is offered to guests. This Lima inn also offers a rooftop terrace, coffee/tea in a common area, and laundry facilities.
- Airport transportation (surcharge)
- Total number of rooms - 9
- Number of floors - 5
- Free breakfast
- Free WiFi
- Rooftop terrace
- Luggage storage
- Number of buildings/towers - 1
- Coffee/tea in common areas
- Laundry facilities
Available in some public areas: Free WiFi
Room Amenities
- Cable TV service
- Desk
Where to Eat
A complimentary continental breakfast is served each morning between 7:30 AM and 10:00 AM.
Start your day with a free continental breakfast, available daily from 7:30 AM to 10:00 AM.
Property Policies
Check-in time starts at 2:00 PM
Check-in time ends at midnight
Special check-in instructions:
Check-out time is noon
Payment types
Children and extra beds
- Children are welcome.
- No pets or service animals allowed
You need to know
Extra-person charges may apply and vary depending on property policy.
Government-issued photo identification and a cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
- No onsite parking is available.
Cash Deposit Required
No rollaway/extra beds available
No cribs (infant beds) available
No elevators
No pets or service animals allowed
Noise-free rooms not guaranteed
- The national sales tax (18%) is charged upon check-out to citizens of Peru regardless of length of stay and to foreigners staying in the country for 60 consecutive days or more. Foreigners who present a valid passport and Andean Migration Card (Tarjeta Andina de Migración) at check-in are exempt from this tax. Furthermore, the tax may apply per room when the room is shared by a taxable and a nontaxable guest.
Property Name
- Posada Peregrinus
- Posada Peregrinus Inn
- Posada Peregrinus Inn Lima
- Posada Peregrinus Lima
We should mention
This property's policy is to refuse certain bookings for the purpose of group events or parties, including pre-wedding stag/bachelor and hen/bachelorette parties. This property offers transfers from the airport (surcharges may apply). Guests must contact the property with arrival details before travel, using the contact information on the booking confirmation. Only registered guests are allowed in the guestrooms. Some facilities may have restricted access. Guests can contact the property for details using the contact information on the booking confirmation. No pets and no service animals are allowed at this property.


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Secured Lending Business Project Manager (AVP)
Secured Lending Business Project Manager (AVP)Responsibilities:
Manage system and process aspect of consumer secured loans. This involves the following:
- Business project manager of a regional loan origination system.
- Contribute towards the digital strategy and implementation for secured loan products.
- Manage end-to-end process creation for home loans from product development, process mapping, customer engagement, acquisition, documentation, disbursement, retention and collateral administration.
- Engage other product teams and stakeholders in the Bank to deliver product bundling, process enhancement or cost management initiatives.
- Lead process enhancements with stakeholders and to implement changes.
- Handle system issues and recovery work with stakeholders.
- Conceptualise, create and maintain technical tools for sales, backroom and product manager's application.
- Create technical training materials for education of sales and process chain stakeholders.
- Excellent ability to communicate well verbally and in writing.
- Strong analytical and communications skills, able to create and to maintain computational tools and presentations for the stakeholders.
- A proven record of successful leading a team in the planning and deployment of a system implementation.
- Able to think independently and out of the box to create or leverage leading industry practices
- Sharp analytical and problem-solving skills to develop simple solutions to complex problems.
- Ability to manage multiple projects/initiatives and work independently


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Call Us: 1-888-514-5151
Shop our supply of Milwaukee hand tools and accessories on sale and save.
Shop our full line of DEWALT power tools and equipment for great savings.
Never risk working with tools that aren't functioning properly.
Save on Makita hammers, drills, nailers, grinders, saws and more. Learn more and request a quote today!
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Listening for God: A CatholicMom Community Lent Playlist
53 minutes ago
I love the alphabet stuff you're doing! I still have no idea what I'm doing for 'Z'. Although I'm only on K so I guess I still have awhile to figure it out. :-)
Thank you for your kind words. I hope everyone is enjoying the lesson plans.
I'm taking the easy route for Z. I'm doing Zacchaeus. LOL!


text:
He owns a 1,000-year-old castle. He's could get a $100 million bonus this year. And, believe it or not, he works for a bank that's 33 percent owned by the government.
In a report that suggests that Wall Street pay packages have returned to pre-bust levels, the Today Show reported this morning on Citigroup's star energy trader Andrew Hall, whose contract stipulates that he can receive a pay package worth up to $100 million this year.
Hall's pay will likely be vetted by the Obama administration's new pay czar Kenneth Feinberg, but NBC's Lisa Meyers points out that the top six Wall Street banks have dedicated no less than $75 billion to pay employees this year. And, despite posting three straight quarterly losses, Morgan Stanley has set aside $6 billion to reward employees.
All of which, Meyers points out, suggest Wall Street's excessive and dangerous pay practices have returned.
Visit msnbc.com for Breaking News, World News, and News about the Economy
The Morning Email helps you start your workday with everything you need to know: breaking news, entertainment and a dash of fun. Learn more


text:
Catching Up With Mike London
By Jeff White (firstname.lastname@example.com)
Catching Up With Mike London
By Jeff White (email@example.com)
'Hoos Remain Work in Progress After Spring Game
By Jeff White (email@example.com)
'Hoos Remain Work in Progress After Spring Game
By Jeff White (email@example.com)
UVa Announces Spring Football Award Winners
Dean and Swanson Named Rock Weir Award Winners
Football vs. UNC (by Matt Riley)
Football vs. UNC (by Matt Riley)
Football vs. Wake Forest (by Matt Riley)
Football vs. Wake Forest (by Matt Riley)
2012 - Appeared in all 12 games ... made four starts ... nine of his completions went for 30 yards or more ... 21 of his completions went for 20 yards or more ... started the Duke, Maryland, Wake Forest and NC State games ... completed 5-of-6 passes for 50 yards against Richmond ... connected on 2-of-3 passes for five yards against Penn State ... threw the first two TDs passes of his career at Georgia Tech ... threw 6-of-8 passes for 56 yards ... passed for 63 yards and a TD at TCU ... made first career start at Duke and threw for 268 yards ... found Tim Smith for a career-long 56-yard strike against Wake Forest ... was 22-of-39 and one TD against Wake Forest ... rushed for first career TD to start scoring at NC State ... was 8-of-10 for 115 yards and a passing TD at NC State ... also rushed for a TD against Miami ... had one passing touchdown on 8-of-17 passing against North Carolina.
Transfered to Virginia from Alabama in May of 2012 ... was a member of the Crimson Tide's 2011 BCS national championship squad ... split time in 2011 with AJ McCarron at quarterback ... saw action in eight games and completed 64 percent of his passes for 163 yards ... made collegiate debut against Kent State when he came off the bench during the fourth series and completed 7-of-14 passes for a 73 yards, his best outing during his Alabama career ... also appeared against Penn State, North Texas, Arkansas, Florida, Vanderbilt, Mississippi and Tennessee ... redshirted the 2010 season.
Came out of Oscar Smith as one the nation's top-ranked passers ... a five-star recruit by Scout.com and a four-star prospect by Rivals.com and ESPNU ... a Parade magazine All-American and a first-team EA Sports All-American ... the No. 1 quarterback nationally by ESPNU and SuperPrep magazine ... the nation's No. 13 player by SuperPrep magazine, a SuperPrep All-American and the publication's top-ranked player in Virginia and the Mid-Atlantic Offensive Player of the Year ... ranked 32nd in the ESPNU 150 and 36th overall in the Scout.com rankings ... listed at No. 67 nationally in the Rivals100 and that publication's No. 2 pro-style quarterback ... the nation's No. 1 quarterback according to ESPNU ... Tom Lemming's No. 3 pro-style quarterback nationally ... played in the 2010 ESPN Under Armour All-America Game in Orlando, Fla. ... a member of the PrepStar Dream Team member as the No. 69 player nationally ... the 2009 Abe Goldblatt All-Tidewater Player of the Year ... two-time first-team All-State in Virginia's largest classification ... finished his high school career as Virginia's career leader in passing yards (10,725) and touchdown passes (119) while finishing second in career completions (636) ... was 48-4 as a four-year starter at Oscar F. Smith High School, which included a 39-1 record in the regular season ... led his team to the 2008 Virginia Group AAA Division 6 State Championship, four Southeastern District titles and three Eastern Region crowns ... as a senior in 2009, Sims threw for 2,960 yards and 33 touchdowns ... passed for 3,167 yards as a junior in 2008 with 38 touchdowns and just four interceptions ... amassed 3,100 yards and 33 touchdowns as a sophomore in 2007 and 1,498 yards and 15 touchdowns as a true freshman in 2006 ... high school teammates with current UVa teammate Tim Smith ... the duo were on the 2008 state title team at Oscar Smith.
UVA Athletics Information
In the NewsRecent Headlines News Archives
- Top Videos
Jeff White
Weekend Notebook: Perrantes Hits HomestretchMen's Basketball2/24/17For point guard London Perrantes, the final regular-season road game of his UVA basketball career is Saturday afternoon at NC State.Casey's Return Buoys CavaliersBaseball2/22/17Derek Casey, who missed the 2016 season while recovering from Tommy John surgery, pitched five strong innings in No. 14 Virginia's home opener.Perrantes Searching for AnswersMen's Basketball2/21/17Senior point guard London Perrantes has made only 16 of 58 shots (27.6 percent) from the floor in his past four games, all Virginia losses.
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Director of News Content
A 1985 graduate of UVA, White worked at the Richmond Times-Dispatch until July 2009. He was honored six times as the state's Sportswriter of the Year.
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text: Singles Category page 30pages on this wiki Add New Page Edit Classic editor History Talk0 Sorting type: Most visited Most visited Alphabetical | singles by alice in chains Pages in category "Singles" Man In The Box Them Bones Angry Chair Don't Follow Down In A Hole Got Me Wrong Grind I Stay Away " "No Excuses" is the lead single from American rock band Alice In Chains 's third EP, Jar of... No Excuses Rooster Sea of Sorrow What The Hell Have I Would? Retrieved from "http://alice-in-chains.wikia.com/wiki/Category:Singles?oldid=4249" Ad blocker interference detected! Wikia is a free-to-use site that makes money from advertising. We have a modified experience for viewers using ad blockers Wikia is not accessible if you've made further modifications. Remove the custom ad blocker rule(s) and the page will load as expected. Categories: Browse Add category Cancel Save


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Government & Organizations, NationalFollow
|Government & Organizations
Features stories about U.S. service members and military operations from around the world.
November 9th, 2015
Episode 273 of 300 episodes
Forest fires are part of the landscape in Northern California especially from June to October. One group of heroes that put their lives on the line to battle the fires are the USDA/U.S. Forest Service Smokejumpers. DLA is now proud to support these heroes of the forest with many of the supplies they need to contain and put out a fire
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Welcome to the daily audio workout for your head.


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Hopefaithbelieve... So sorry for ur bfn... Now ur fs knows how ur body works, hopefully they will change ur protocol for next time and it be right for u.. All the best xx
thought I'd posted about our OB appt but just realised I hadn't.. Went really well.. Margo is fantastic!! Did a quick scan for us and saw our little gb again with a faster hb :-) wants us to go back at 10 weeks another scan just to keep our minds at ease which is awesome so that's booked for the 19th march... Then we go back on the 2nd April which I'll be 12.1 weeks.. So happy and excited that I chose the right OB.. DH was really pleased as well.. Now we r just counting down til the next appt. other than that still no ms thankfully..
Hope everyone else is well..


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Adhya Shetty Hot Bikini Maxim India April 2013
Indian model Adhya Shetty photographed by Amit Sharma for the cover shoot of the men's magazine Maxim India for their April 2013 issue.
This entry was posted in Bollywood, Hot Special, Latest Fashion, Magazines, Photoshoots and tagged Adhya Shetty, Adhya Shetty Hot Bikini photo shoots 2013, Amit Sharma, April, india, Maxim India April 2013, model. Bookmark the permalink.


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Scottish trainer believes that Australian raider Takeover Target should not be invited to race in Britain this year
Ascot is relishing the return to the royal meeting of the iconic Australian sprinter, Takeover Target, and his former taxi driver trainer, Joe Janiak. Together, they are box-office. But at least one leading British trainer believes the horse should not have been invited.
Mark Johnston has no argument with any financial inducements Ascot might have offered. His issue is with the drugs that Janiak admits administering to his star horse. In his house magazine, Kingsley Klarion, the Scot addresses the subject in a comment piece illustrated by an oiled-up bodybuilder with a horse's head and headlined "Invitation to Cheat?"


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Valencia-Palomo G.,Technological Institute of Hermosillo |
Rossiter J.A.,University of Sheffield
Control Engineering Practice | Year: 2011
The prime aim of this paper is to embed a predictive control (MPC) algorithm with constraint handling capabilities into a programmable logic controller (PLC). In order to achieve it, this paper develops parametric approaches to MPC but differs from more conventional approaches in that it predefines the complexity of the solution rather than the allowable suboptimality. The paper proposes a novel parameterisation of the parametric regions which allows efficiency of definition, effective spanning of the feasible region and also highly efficient search algorithms. Despite the suboptimality, the algorithm retains guaranteed stability, in the nominal case. A laboratory test was carried out to demonstrate the code on real hardware and the effectiveness of the solution. © 2011 Elsevier Ltd. Source
Valencia-Palomo G.,Technological Institute of Hermosillo |
Rossiter J.A.,University of Sheffield |
Jones C.N.,Automatic Control Laboratory |
Gondhalekar R.,Osaka University |
Khan B.,University of Sheffield
Proceedings of the American Control Conference | Year: 2011
This paper looks at the efficiency of the parameterisation of the degrees of freedom within an optimal predictive control algorithm. It is shown that the conventional approach of directly determining each individual future control move is not efficient in general, and can give poor feasibility when the number of degrees of freedom are limited. Two systematic alternatives are explored and both shown to be far more efficient in general. © 2011 AACC American Automatic Control Council. Source
Novel programmable logic controller implementation of a predictive controller based on Laguerre functions and multiparametric solutions
Valencia-Palomo G.,Technological Institute of Hermosillo |
Rossiter J.A.,University of Sheffield
IET Control Theory and Applications | Year: 2012
This study presents a novel programmable logic controller (PLC) implementation of a constrained predictive control (MPC) algorithm based on Laguerre functions and multi-parametric quadratic programming (mp-QP). First, the study shows how Laguerre functions can be used in conjunction with mp-QP to achieve a large decrease in both the online computations and data storage requirements while increasing the feasible region of the optimisation problem for MPC; extensive simulation results are given to back this claim. Next, the study shows how the algorithm can be embedded on an industrial PLC using the IEC 61131-3 programming standard. A laboratory test was carried out to demonstrate the code on real hardware. © 2012 The Institution of Engineering and Technology. Source
Valencia-Palomo G.,Technological Institute of Hermosillo |
Rossiter J.A.,University of Sheffield |
Lopez-Estrada F.R.,Instituto Tecnologico de Tuxtla Gutierrez
ISA Transactions | Year: 2014
Simple predictive control (MPC) algorithms produce a feed-forward compensator that may be a suboptimal choice. This paper gives some insights into this issue and simple means of modifying the feed-forward to produce a more systematic and optimal design. In particular, it is shown that the optimum procedure depends upon the underlying loop tuning and also that there are, as yet under utilised, potential benefits with regard to constraint handling procedures, which helps to improve the computational efficiency of the online controller implementation. A laboratory test in a programmable logic controller (PLC) was carried out to demonstrate the code on real hardware and the effectiveness of the solution. © 2014 ISA. Source
Electron raman scattering in asymmetrical multiple quantum wells system with an external electric field: Fröhlich interaction
Betancourt-Riera R.,Technological Institute of Hermosillo |
Betancourt-Riera R.,University of Sonora |
Rosas R.,University of Sonora |
Riera R.,University of Sonora
Journal of Computational and Theoretical Nanoscience | Year: 2012
The differential cross section for an electron Raman scattering process in a semiconductor multiple GaAs/AlGaAs quantum well with the presence of an external uniform electric field is calculated for T = 0 K. A description of the confined phonon modes, considering the Fröhlich interaction is presented. We assume single parabolic conduction band with one electron. The emission spectra and the effect for different electric field values are discussed. Singularities in the spectra are found and interpreted. The ERS studied here can be used to provide direct information about the electron band structure of these systems. Copyright © 2012 American Scientific Publishers. All rights reserved. Source


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It may not have won an Oscar but the short film made by Tom Lane won his girlfriend's heart.
As Tina Kilford and a couple of her friends settled into their seats at the cinema, she was astonished to see her boyfriend appear on the screen.
He was standing in their living room, dressed in a dinner jacket, and holding a series of hand-written placards, one of which read "Will You Marry Me?". The romantic short was filmed by Mr Lane with the help of a couple of friends. He persuaded staff at the Cineworld multiplex in Weymouth, Dorset, to


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Mehle N.,Slovenian National Institute of Biology |
Trdan S.,University of Ljubljana
Journal of Pest Science | Year: 2012
Many thrips are pests of commercial crops due to the damage they cause by feeding on developing flowers or vegetables. Thrips may also serve as vectors for plant diseases, such as tospoviruses. Their small size and predisposition towards enclosed places makes them difficult to detect by phytosanitary inspection. In this review, several methods available for identifying thrips, including their advantages and disadvantages, are discussed. A combination of different methods gives the most reliable identification. Relatively new morphometric, molecular and biochemical methods for identifying thrips species represent valuable alternatives for situations in which correct identification with classical morphological methods is very difficult, time consuming or virtually impossible. However, traditional morphological methods should not be neglected, especially because adequate identification using morphological keys is usually an indispensable first step in the development and validation of these new modern methods. In addition, modern systems may still require specimen identification to the genus level via morphological keys, or such keys may be recommended to confirm the results of modern identification methods. © 2012 Springer-Verlag. Source
Grego M.,Slovenian National Institute of Biology |
Riedel B.,University of Vienna |
Stachowitsch M.,University of Vienna |
De Troch M.,Ghent University
Biogeosciences | Year: 2014
The impact of anoxia on meiobenthic copepod species was assessed by means of a field experiment. Four plexiglass chambers were deployed in situ in 24 m depth to simulate an anoxic event of 9 days, 1 month, 2 months and 10 months. From normoxic to anoxic conditions, we recorded a drop in copepod density and species richness. With increasing duration of anoxia the relative abundance of the individuals of the family Cletodidae increased, and they survived the 1 month and 2 month anoxia, the latter with few specimens. They were the true "winners" of the experimentally induced anoxia. Dominance did not increase in the deployments because not one, but several species from this family were tolerant to anoxia. The overall rate of survival was the same for males and females, but no juvenile stages of copepods survived in anoxia. During a recovery phase of 7 days after a short-term anoxia of 9 days, harpacticoid copepod density did not increase significantly, and there was only a slight increase in species diversity. We concluded that no substantial colonisation from the surrounding sediment took place. The survivors, however, showed a high potential for recovery according to the number of gravid females, whose number increased significantly once the oxygen was available again. These findings imply that substantial energy is allocated to reproduction in the recovery phase. © Author(s) 2014. Source
Koren A.,University Clinic Golnik |
Motaln H.,Slovenian National Institute of Biology |
Cufer T.,University Clinic Golnik
Cellular Oncology | Year: 2013
Introduction: Lung cancer is the most lethal form of cancer in the world and despite significant therapeutic improvements that have been made, its survival rate still remains low. The latter is mainly due to the acquisition of resistance to systemic treatment regimens which, in turn, may be due to the presence of cancer stem cells (CSCs) within the primary tumors. CSCs constitute a subpopulation of cells that are highly tumorigenic and that exhibit biological properties similar to those of normal tissue stem cells, including an unlimited self-renewal capacity, an extensive proliferative capacity and a capacity to generate differentiated progeny. A better understanding of the signaling pathways that regulate lung CSC maintenance, proliferation, and tumorigenicity could thus lead to the design of improved approaches to lung cancer treatment. Aim: In this review we will discuss the current knowledge on lung CSCs, their biological properties and their putative clinical relevance. By employing currently available data, we will evaluate the prognostic value of several lung CSC markers. In addition, we will discuss the release of CSCs from tumor tissue into the blood circulation via epithelial-mesenchymal transition (EMT) as an important step towards acquiring a metastatic phenotype. Finally, we will provide an outlook into novel CSC-targeting approaches for achieving less invasive diagnostic procedures and improving long-term therapeutic options. Conclusion: Lung CSC research has gained considerable momentum to both basic and clinical applications, both aiming to identify a reliable panel of markers for lung CSCs and to clarify their function, with the final goal to develop a CSC-targeted therapy that will result in the complete elimination of CSCs for achieving significantly better long-time survival of lung cancer patients. © 2013 International Society for Cellular Oncology. Source
Aliphatic and polycyclic aromatic hydrocarbons in sediments of the Slovenian coastal area (Gulf of Trieste, northern Adriatic)
Bajt O.,Slovenian National Institute of Biology
Environmental Monitoring and Assessment | Year: 2012
The distribution and sources of aliphatic and polycyclic aromatic hydrocarbons (PAH) were determined in sediments at seven sites around the Slovenian coastal area. The potential toxicological significance was also assessed using biological thresholds. The results of the analyses showed higher concentrations of hydrocarbons in the Port of Koper and in the Marina of Portoroz. The influence of pollution was also evident in rather higher concentrations of hydrocarbons in the surrounding area in the Bays of Koper and Piran. Concentrations of hydrocarbons decrease toward the central part of the Gulf of Trieste. The major component of the aliphatic fraction was the unresolved complex mixture. Concentrations of the total resolved aliphatic hydrocarbons were in a range from 689 to 3,164 ng g-1. Concentrations of the total PAHs were between 330 and 1,173 ng g-1. Polycyclic aromatic hydrocarbons are primarily of pyrolytic origin with some smaller contributions of the petrogenic, while the aliphatic are mostly of petrogenic origin with significant amounts of biogenic derived compounds of terrestrial and marine origin. Strong evidence of the diagenetic origin of perylene in the investigated area was also found. Quite a good linear relationship between PAH concentration and TOC and between aliphatic hydrocarbon concentrations and TOC was observed. The principal component analysis showed differences between the nearshore and offshore sites. In general, the investigated area is moderately contaminated by hydrocarbons. Concentrations of PAHs, hydrocarbons of high concern, are below the levels (effects range low and the effects range median) associated with adverse biological effects. © Springer Science+Business Media B.V. 2012. Source
Temporal processing of vibratory communication signals at the level of ascending interneurons in Nezara viridula (Hemiptera: Pentatomidae)
Zorovic M.,Slovenian National Institute of Biology
PLoS ONE | Year: 2011
During mating, males and females of N. viridula (Heteroptera: Pentatomidae) produce sex- and species-specific calling and courtship substrate-borne vibratory signals, grouped into songs. Recognition and localization of these signals are fundamental for successful mating. The recognition is mainly based on the temporal pattern, i.e. the amplitude modulation, while the frequency spectrum of the signals usually only plays a minor role. We examined the temporal selectivity for vibratory signals in four types of ascending vibratory interneurons in N. viridula. Using intracellular recording and labelling technique, we analyzed the neurons' responses to 30 pulse duration/interval duration (PD/ID) combinations. Two response arrays were created for each neuron type, showing the intensity of the responses either as time-averaged spike counts or as peak instantaneous spike rates. The mean spike rate response arrays showed preference of the neurons for short PDs (below 600 ms) and no selectivity towards interval duration; while the peak spike rate response arrays exhibited either short PD/long ID selectivity or no selectivity at all. The long PD/short ID combinations elicited the weakest responses in all neurons tested. No response arrays showed the receiver preference for either constant period or duty cycle. The vibratory song pattern selectivity matched the PD of N. viridula male vibratory signals, thus pointing to temporal filtering for the conspecific vibratory signals already at level of the ascending interneurons. In some neurons the responses elicited by the vibratory stimuli were followed by distinct, regular oscillations of the membrane potential. The distance between the oscillation peaks matched the temporal structure of the male calling song, indicating a possible resonance based mechanism for signal recognition. © 2011 Maja Zorović. Source


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I'm a long term renter, so yeah, pauper town!
I won't elaborate much, but I feel like we haven't had enough income to sustain our lifestyle/financial obligations since we had DS. We've certainly lost the ability to save money, as paying the bills takes priority.
I'm hoping to turn things around next year when DS starts school. It'll enable DH to seek full time work (he cares for DS during the day and works casually). I'll also be free of paying preschool fees which are a financial stretch this year ($165 a week), and my car loan will be paid off.
Realistically we won't be entering the property market any time soon. It's still a goal of ours though, one I hope we achieve in time.


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The US Department of Labor (DOL) has issued a final rule that updates equal employment opportunity (EEO) requirements with respect to apprenticeships. Current protections are expanded to include disability, age, genetic information and sexual orientation.
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"Kerala leads our country in all social and human development indicators. It is the most literate state and female literacy and life expectancy for women have reached levels prevailing in some advanced countries. The women of Kerala have been truly empowered and enjoy full equality. There have been many many distinct women authors, social activists, doctors, lawyers, scientists, professors...the first Supreme Court judge was from Kerala and all these women have made their mark in the state and else where in the country," said Gandhi said at a rally here.
The UPA chairperson also held discussions with top leaders of the state and inaugurated a private research foundation and a new building of the Women's Centre of the Church of South India (CSI). She is also expected to visit the Rajiv Gandhi Centre for Biotechnology.
Reports say that human development indices like elimination of poverty, primary level education, and health care in Kerala are among the best in India.
According to the 2001 census, Kerala has the second highest literacy rate (89.9 percent) among the Indian states after northeastern Mizoram (91 percent) and the life expectancy (73 years) is among the highest in India. Literacy is 88 percent among females and 94 percent among males.
Kerala is one of the most sought after tourist destinations in the world. In 2005, the state was listed among the top 50 destinations of a lifetime by National Geographic.


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Nov 30, 2016, 07.48 AM | Source: Reuters
Iran has written to the Organization of the Petroleum Exporting Countries saying Saudi Arabia needs to cut oil output to 9.5 million barrels per day, an OPEC source told Reuters.
Saudi Arabia has previously indicated it was prepared to reduce its production only by 0.5 million bpd from current levels of 10.5 million bpd.
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Belleville Dentists at Family Dentistry of Bellville and Associates provide cosmetic, general and restorative dentistry in a Convenient Belleville Michigan Location.
Family Dentistry is located at the address 11784 Belleville Rd in Belleville, Michigan 48111. They can be contacted via phone at (734) 699-1808 for pricing, hours and directions. Family Dentistry specializes in Migraines, Oral Disease, Stained Teeth.
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The office was dirty and the older, bald, large dentist was very rude. The front desk staff very unfriendly and unknowledgeable. The decor, hello can you say the 70's are calling!!! The patient chair did not even have an arm on it. And about 4 different colors of carpeting that trip you while walking down the hallway.
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Globalization in Brazil and its Overall Effects
While the world is going through recession and economic downturn has especially hit hard the developed economies like the U.S and Britain and adversely impacted every other nation in a globalizing economy, a group of nations especially the developing ones like Brazil are on a growth trajectory that has remained almost untouched by the adverse economic impact.
There could be several reasons how and why some of these nations remained unscathed by the economic downturn. The one fundamental reason appears to be their internal strength. The internal strength shared in common by these nations include – a large internal market that fuels their growth, an expanding economy largely due to the investment efforts of their national governments on social sector programs, large foreign investment into their economies in recent years, among several other important factors like foreign remittances from their citizens abroad.
Brazil has grown at a phenomenal pace over the last decade. The nation has already emerged as the leading voice of the major developing nations:
They are a leading voice on the emerging markets in international affairs. They rallied the major developing nations to challenge the rich world's agricultural subsidies, forming a group now known as the G5. At Brasília's prodding, the ambassadors of Brazil, China, India and Russia now meet monthly in Washington to coordinate a common BRIC policy strategy, often to counter U.S. positions. Pushing its "south-south" agenda, the Lula government has opened 35 embassies since taking office in 2003, most of them in Africa and the Caribbean. Brazil also leads a widely acclaimed peacekeeping mission in Haiti, one of the hemisphere's biggest basket cases (Margolis, April 9, 2009).
According to a Goldman Sachs analysis that addresses these economies as BRICs economies (acronym for Brazil, Russia, China, and India), they are the emerging global economic powers that are, in the next 40 years, poised to grow larger than the G6 in US $ terms, and by 2025 they could be larger than half the size of the G6. India's economy for instance could be larger than that of Japan by 2032, and the Chinese economy is likely to outgrow that of the US by 2041, and everyone else by as early as 2016. Over the next 50 years, Brazil's GDP growth rate according to Goldman Sachs report is expected to average 3.6 percent. The size of Brazil's economy overtakes Italy, and France by 2025 and 2031 respectively while UK and Germany would be left behind by Brazil's economy by 2036 (Goldman Sachs, 2003). That's truly possible because of globalization impacts on Brazil.
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Brazil's self determination has been centuries in the making......with many millions of poor they have a long way to go be classified as an industrial democracy. AT least they have the democracy part.......good to see that the cia has not toppled them!!!


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Earlier tonight, Bo Jackson hosted the All For One Event to celebrate the athletes, the designs, and the art of the Nike Trainer 1.2. The special event, held at Niketown New York, displayed a lineup of 11 limited edition Nike Trainer 1.2 models, known as the "All For One" Pack, which were developed for some of the world's most dominant athletes. To go along with the sneakers, 11 of today's top artist's were commissioned to create a piece of artwork inspired by the athletes in which the shoes honor.
The Nike Trainer 1.2 "All For One" Pack retails for $350, and includes one pair of player edition shoes in a premium footwear box, as well as the framed artwork inspired by the sneakers. Only 12 prints of each athlete posters were made and a first-come, first-serve raffle took place at Niketown in NY when the event kicked off to determine who would have the opportunity to buy each of the "All For One" Pack's.
Continue reading for a closer look at the shoes and more details about the artwork.
Bo Jackson (1989)
Steve Rura for Bo Jackson, 1986
"Bo Jackson is legendary for his dual athleticism and All-Star status in both American football and baseball. 1986 marked Bo's entrance into professional sports, and it was also the year Nike first developed the now classic Air Trainer 1 shoe design. Bo's image quickly became synonymous with Nike cross-training during his career."


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|Mr. John Manning was very polite and gave me the exact info I was looking for With extra useful advices. I wish him all the luck of the world.
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There has always been a need for skilled machinists, but with the advent of technology the skills and knowledge needed to succeed in the industry have increased. Today's Computer Aided Manufacturing machinists must know precision machine tools, equipment and systems and be able to develop programs that will allow them to process metal or plastic parts to engineering specifications. The U.S. Bureau of Labor Statistics projects that Texas will have 2,580 job openings each year for the next seven years in the machining fields listed below. That's more than 18,000 skilled, qualified personnel that will be needed to fill open positions through 2022.
TSTC offers an Associate of Applied Science degree in Computer Aided Manufacturing Machinist. For those wishing to enter the workforce more quickly or add to an existing knowledge base, TSTC also offers two certification levels in Computer Aided Manufacturing Machinist - one which requires 19 hours to complete and one which requires 39. Most students take all three programs, which were designed to be completed in progression. Through a unique partnership with HAAS Automation Inc., TSTC has established a regional training facility that enhances the learning experience. In the laboratory, where most of the student's time is spent, the machines and software are the same as those used in today's fast-paced and highly-competitive manufacturing environment. Graduates find excellent career positions in large and small companies throughout Texas - particularly in Marshall-Longview, Dallas-Fort Worth, Houston and Austin-Round Rock - as well as nationally.
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Question about Coby MP-C7085 MP3 Player
Hey I accidentally deleted all the directories exept the multimedia one any ideas on how to get them back or create new ones
Posted by EZ rider on
Try this link
for the firmware
or for recovery,try this one.
Posted on Apr 04, 2008
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Pal Ontologie Fran Aise Description Zoologique Et G Ologique de Tous Les Animaux Mollusques Et Rayonn S Fossiles de France, Volume 3
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Pal Ontologie Fran Aise Description Zoologique Et G Ologique de Tous Les Animaux Mollusques Et Rayonn S Fossiles de France, Volume 3 by Alcide D' Orbigny
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Event: Ranbir Kapoor, Konkana Sen Sharma and Ayan Mukherjee launched the trendy and stylish range of Provogue-WAKE UP SID T Shirt collection at Inorbit Mall, Malad, Mumbai.
Guest List: Konkona Sen Sharma, Ayan Mukherjee, Ranbir Kapoor
Venue: Inorbit Mall, Malad, Mumbai.
Date: 29-Sep-2009
Bollywood celebs Alia Bhatt and Varun Dhawan sizzled the ramp at Fevicol Caring with style fashion show.
Bollywood celebs Amitabh Bachchan, Varun Dhawan, Disha Patani, Iulia Vantur, Tara Sharma, Manish Paul, Sonali Bendre, Suzzanne Khan, Priya Bapat, Terrence Lewis, Himesh Reshammiya among others sizzled...
Bollywood celebs Shah Rukh Khan, Nikhil Dwivedi, Shatrughan Sinha, Satish Kaushik, Premila Chopra, Simi Garewal, Rekha, Padmini Kolhapure, Udit Narayan among others were snapped at 4th Yash Chopra awa...
Bollywood megastar Amitabh Bachchan, Ustad Zakir Hussain, Pt. Birju Maharaj, Ustad Rashid Khan, Suresh Wadkar, Pankaj Udhas were snapped at Ajvasana's Vasantostav 2017
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14 Parks near Old Town, Florida
Cross City, Florida 0.68 miles NW
Manatee Road, Florida 13.92 miles SE
Steinhatchee, Florida 16.75 miles NW
4114 NE Hwy 349 Old Town, Florida 32680 (map) | (352) 542-0033
Sites: 60 | Latest Rate: $31.00 | 16 Reviews
|Clean Restrooms:
|Clean Showers:
Feb 2017 - $31.00
Hidden gem! Owners were very nice and helpful. Beautiful campground with a lot of space between sites. - dtfoster
Dec 2016 - $31.00
The owners are lovely people. I left a message and they called me back very promptly. We arrived after dark and they drove their car to our site so we could follow them. The sites are very wide, long and level. Lots of big, old trees. We tow a car and there was plenty of room to get in and out. The hookups were lighted to make hooking up after dark much easier. There was a grassy dog park. We would definitely return to this park. The owners were so very gracious! - Tiffin Allegro
Dec 2015 - $31.00
Wonderful privately owned park for adults ( just be 40 or older). 60 very long, level and spacious pull thru sites. Free wi-fi and cable, heated pool, hot tub, clubhouse, fenced dog park. Roads and sites are compacted rock.
Very open and lots of trees. Picnic table at each site. Very clean and reasonable. Would recommend for an over night or a winter! - travelswithpuppies
2241 SE Hwy 349 Old Town, Florida 32680 (map) | (352) 542-9500
Sites: 44 | Latest Rate: $22.00 | 24 Reviews
|Clean Restrooms:
|Clean Showers:
Dec 2016 - $22.00
Nice smooth road from highway 19/98 to the park entrance. There is a courtesy phone in the office where you can call the manager. He comes to the office right away. He escorted me to a good level site. I was able to easily hook up my electric and water. I took my dogs to the pet run so they could do their business. It is was very quiet there and I had a good restful night. Very friendly gentlemen who runs the place. - maine charactor
Mar 2016 - $16.00
A well maintained and medium-sized RV park, quite a bit off the beaten track which means it's quiet. Very pleasant surroundings overall with lots of trees, palms, etc. Owner was pleasant and friendly. Fair WiFi (apparently better in other parts of the park than our site), moderately ok cable quality and good selection, and good Verizon signal. There were only two spots available when we arrived -- no reservations, just assurances, and only cash or check. There were a lot of one- and two-nighters coming through. We stayed 8 days and enjoyed them all. Our site hookups were all good, but no sewage. Since we left every other day to see some local attraction we used the dump each time, which worked fine for us. Some long-termers had portable dump tanks with wheels. Our water pressure was low, about 20psi, but seemed okay in the showers. Picnic table but no fire ring/pit/grill. And despite it being "in the middle of nowhere," there were a lot of things to do close-by. Private bathroom/showers which were clean. Two washers, two dryers in the laundry and they did a good job. Main path is paved, sites are sandy, grassy, pine needles. Everyone was friendly. Price was with Escapees discount. This is an excellent value! We would stay here again. - RobtL
Feb 2016 - $30.00
The website says "full hookups", but only some sites have sewer - ours did not. Sand site, no social activities. Strange rule about lights off after 7 PM to avoid interfering with infrared security cameras.
On the plus side, it was very quiet. - Neil_and_Sandy
21354 SE Co Road 349 Old Town, Florida 32680
Sites: don't know | Latest Rate: $20.00 | 1 Reviews
|Clean Restrooms:
|Clean Showers:
Feb 2013 - $20.00
This beachfront campground is administered by Dixie County within the Lower Suwanee National Wildlife Refuge. This is a breathtakingly beautiful place on a white sand beach, but apparently it is heavily used for local partying on the weekends, and as a result there is trash everywhere. We picked up multiple bags of trash during our 4 day stay. There is a bathroom with flush toilets and 1 shower that has hot water: not very clean. There is no potable water, WiFi, or cell phone reception. There is a dumpsite and a brand new fishing pier. Come with a good stock of water and groceries, because the nearest shopping is at least a 30 minute drive. The only noises here are the wild hogs rooting in the bush, and the tide splashing up on the beach. The fee quoted is for non-county residents; residents pay $10. - Wereapair
1218 SE 346 Hwy Old Town, Florida 32680 (map) | (352) 542-7800
Sites: 44 | Latest Rate: $14.00 | 32 Reviews
|Clean Restrooms:
|Clean Showers:
Jan 2017 - $14.00
Fantastic, quiet campground. Owners are great. 50 amp service and full hookups, wifi at the club house, pool is beautiful but not heated - still refreshing on a hot day. Dog friendly. We will definitely make this a yearly stop for a month or more. Very reasonable price per month. - Lucy Belafonte
Jun 2016 - $28.00
The name Hideaway completely suits the location. Due to this fact, cell service was weak and sporadic for both AT&T & Verizon. Their advertisement regarding "major" cable TV service related to only 4 channels, and Wi-Fi was non-existing, even in their Wi-Fi hot-spot area. The sites require mowing. Grass is tall and there are a lot of ant nests throughout the campground. May be good for a one-nighter. We will not return to this campground. - LM Stiers
May 2016 - $15.00
Very nice resort with gravel roads and wide level grass sites. Long back in and pull thru sites. Many towering trees for almost complete canopy of shade. Only a few sites with satellite signals. Cable tv, weak antenna TV, no wi-fi. Ok cell signal. Nice pool and walk paths to river. On-site fishing pond. OK for big rigs. Park clean and staff helpful. Charge extra $2 per nite for 50 amp and a $4 dump fee for FHU site. Will stay there again. - Pepper Dan
28872 SE 19 Hwy Old Town, Florida 32680 (map) | (352) 542-7680
Sites: 70 | Latest Rate: $28.00 | 5 Reviews
|Clean Restrooms:
|Clean Showers:
Mar 2016 - $28.00
This campground has changed owners and management. It is very clean! The river is beautiful! Restrooms are very clean. Management is very nice and helpful!! Great place to stay!! - Bald Hill 156
Aug 2015 - $25.00
The park is under new management. This park has had a lot of landscaping and TLC put into it. There are currently 2 new owners which have put a lot of money back into the park. The bath house is clean, the old gazebo is gone and the junk has all been cleared away. This is a nice place to stay! If you are looking for a great place to camp and fish, this is your place! - Bald Hill 156
Feb 2014 - $25.00
Bathhouse is disgusting. Not cleaned since we have been here. Mold in soap dispenser. Commode stopped up and not fixed. Horrible smell. Not handicapped accessible. Large person could not use bathroom or showers. The place is rather junky. Would not camp here again. The owners are very nice, but the place needs lots of TLC. - Bill Lawson
Old Town, Florida (map) | (352) 542-8365
Sites: 85 | Latest Rate: $40.00 | 47 Reviews
|Clean Restrooms:
|Clean Showers:
Nov 2016 - $40.00
Quick stop - just to sleep but lovely setting with lots of family activities - very accommodating to novice RV'ers. - Sarah-5cat
Jun 2016 - $35.00
Stayed here several times and have always had a nice experience. Pontoon boat rental is available which is a plus. Large open space and nature trails. Plenty of room for kids and dog walking. The owners are very accommodating and even let us use their oven one Thanksgiving. - Cashlin
May 2016 - $65.00
We were given a site that looked 1/2 a site. We were 8' from our neighbor on our awning side and right against the utility post on the other. Somewhat level, gravel and dirt with no picnic table. On a walk around the park, in the back we discovered at least 40 picnic tables stacked up. We asked the office why they were there they told is campers moved them from the spot they were placed and they didn't want to pay an employee to move them back. The office said they would rent us one for $25.
The only place you could use a cell phone was at the pool. They had a hot spot attached to the fence, and to use it you could not be more than 3' away. Also the pool was heavy with chlorine probably because of the 3 babies in diapers in there. Over priced and will never go back. - Walt Deptula
50 Southeast 74th Avenue Cross City, Florida 32628 (map) | (352) 498-0490
Sites: 36 | Latest Rate: $20.00 | 3 Reviews
|Clean Restrooms:
|Clean Showers:
Jun 2014 - $20.00
This park has both good and bad points. it's hard to get in and out. Also, the staff aren't good at giving directions, and one bad turn, you're stuck in pure sand! The good is that it's a fun park. The music camp for kids is the best I've ever seen, and one I'd recommend to every parent. You'll be amazed at what your child learns in just three days. People are nice here, but warning, people often come here to party, so it can get loud/rowdy. The experience was overall great, and we'll likely stay here again. - David Paul
Apr 2010 - $37.00
Campground was adequate for an overnight stay. Individual in the office was very friendly. He led us to our campsite which was a good thing since we drove through a field: no road of any sort to access our site. I have no problems with paying a small amount extra for more than two adults but $5 per adult extra is a little much! Nightly rate for 2 adults is $27. Site was sandy. Swimming pool is under construction. Bathrooms were clean but small: two showers and one toilet. Overpriced for what we got! - knipp4la
Oct 2009 - $20.00
The previous horrible review was 2 years ago. This campground is under new ownership and they are working hard to make it nice. I asked for an open site for my roof top satellite and they were very accommodating. My Verizon phone worked to get on line with a strong EVDO signal. It's right along 98, so not searching for it. No road noise. There were quite a few full time residents, but all were very nice, quiet and respectful. I wouldn't hesitate to stay there again. - airstreamingypsy
6470 SW 80th Ave Trenton, Florida 32693 (map) | (352) 463-0800
Sites: 100 | Latest Rate: $30.00 | 18 Reviews
|Clean Restrooms:
|Clean Showers:
Oct 2016 - $30.00
They give discounts to military retirees and disabled military. Indoor swimming pool, meeting room, a conference center and of course the springs. Quiet park, good utilities, level sites and lots of shade. - Walt Deptula
May 2015 - $23.00
The first few days was OK. Memorial weekend was a disaster. On Thursday they moved in a huge tent city with close to 100 Haitian migrant workers. They were transported in by bus. You couldn't get in the bath rooms - men sitting in chairs and on ground all in the building. They got off bus and went directly to swimming pool. Filthy in their work clothes jumped into pool. We thought this was a quiet family oriented park. We were stuck here, couldn't find another place because of the holiday weekend. I would not recommend this place to anyone. Poorly organized and poorly run. - Diana smith
Apr 2015 - $23.00
This park is a work in progress, having been taken over by a veteran's support group last year. Sites are close and dirt, access is via a narrow sand lane. The attendant who sent us to our site didn't know what side the power was on so we had to drive through a site to turn around and enter from the other direction. Power, water and sewer connections were all satisfactory. Do not try to take a big rig to the end of the main loop and turn around since trees are in the way and way to tight to turn. We walked the route after finding the site with utilities on the wrong side. We will not return to this park. - Teacher's Pet
11650 NW 115 Street Chiefland, Florida 32626 (map) | (352) 493-6072
Sites: 72 | Latest Rate: $11.00 | 75 Reviews
|Clean Restrooms:
|Clean Showers:
Jan 2017 - $11.00
Nice park. Staff and rangers friendly and helpful. Facilities clean and up to date. Plenty of hiking/biking trails. Great boardwalk along the spring to the river and around spring head. Sand/gravel loop roads could use some smoothing out. Good day visit facilities (playground, pavilions, picnic benches, grills) and a good concession with wi-fi. Canoe/kayak rentals, river tour available. Cell phone spotty. All sights look pretty level. Ours was perfect. - GDoug
Jan 2017 - $20.00
Including tax we were at $23/night. Verizon cell had a sketchy voice signal and no data signal (could not hot spot). Sprint Mifi had zero signal. There is free wifi at the sports/bbq building at the spring. Despite lots of trees, we were able to receive DirecTV from our site (MAG1 loop site 29). I imagine sat signal varies from site to site and even varies depending on where the dish is within the site. Our pull-thru site was rated for max 35' but we had no problem with our 40' motorhome plus tow car. We even saw a 45' coach in another pull-thru site. I suggest calling the park office prior to booking if you want to try to squeeze into a site. They'll tell you if they think you can "really" get in. The park is perfect for lots of outdoor activities. Park staff and camp hosts were wonderful. We enjoyed our time here and would definitely stay here again. - GottaGoNow
Nov 2016 - $20.00
Dirt roads bumpy, had to use the hitch slide (short bed truck with fifth wheel) to back in to site because of a tight site (trees), narrow road and cars in sites across, but was doable on first try with a skilled driving companion's directions. MANY armadillo, so we had to keep a tight leash on the dogs. Deer came right through between sites at all hours and were easily spotted on trails. Sunset pontoon ride was very pleasant and informative and extra special on the super moon night. Sites are not too close to each other and there is varying amounts of vegetation between each. No cell reception at all. - Anja_vom_Landschaft
4802 SW 358 Hwy Steinhatchee, Florida 32359 (map) | (352) 498-5979
Sites: 14 | Latest Rate: $50.00 | 17 Reviews
|Clean Restrooms:
|Clean Showers:
May 2016 - $50.00
The only concern causing us to rate this park lower than a 9 or a 10 is the close layout of the sites. Our motorhome with slideouts on one side and our awning on the other did not completely fit within the side boundaries of the site. So if anyone had been in the sites next to us our awnings would've possibly touched each other's units. The sites are very close to each other and only just barely wide enough. The sites patio/deck and picnic table are situated behind the site so that the site's widths may be kept as small as possible. Having said that, the sites themselves were the nicest we've been in that aren't concrete, they just need to be wider.
The entrance to the park is very narrow for an RV, and if you have a toad you'll need to unhook at Casey's Store before pulling into the park.
This is a lovely RV park to stay in. And the new owners (since October 2015) have everything nice, clean, and well maintained. The pool area with covered deck, ceiling fans, and picnic tables is the nicest we've seen in 3 years of fulltime RVing. Since we were the only ones there we had the feeling of camping in our own backyard - really nice! And the WiFi was excellent!
If you have a small camper or RV, or if you don't mind "touching awnings" then this is a great place to stay. But it's too tight for us to camp in the future. - TCandME
Mar 2015 - $1.00
Went by this RV park and found that it is closed and no info. Asked around and everyone said that it was the best RV resort around, but with the new owners it closed. - sjsaxt
May 2014 - $37.00
Clean CG with very nice hosts. They let me use their power washer as my windshield was completely covered in May Flies. The sites are gravel and level but are open with no shade. They have a nice pool. All the sites are back in and are easy to do so except the last two because of the buildings in front. The signage at the road was extremely poor and we missed the entrance and had to drive a few miles toward town to find somewhere to turn around. - HRambler


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Guenther E.,Inter Science |
Guenther E.,Institute fuer Bildgebende Diagnostik |
Klein N.,Inter Science |
Klein N.,Institute fuer Bildgebende Diagnostik |
And 5 more authors.
Biochemical and Biophysical Research Communications | Year: 2015
Electroporation, the permeabilization of the cell membrane by brief, high electric fields, has become an important technology in medicine for diverse application ranging from gene transfection to tissue ablation. There is ample anecdotal evidence that the clinical application of electroporation is often associated with loud sounds and extremely high currents that exceed the devices design limit after which the devices cease to function. The goal of this paper is to elucidate and quantify the biophysical and biochemical basis for this phenomenon. Using an experimental design that includes clinical data, a tissue phantom, sound, optical, ultrasound and MRI measurements, we show that the phenomenon is caused by electrical breakdown across ionized electrolysis produced gases near the electrodes. The breakdown occurs primarily near the cathode. Electrical breakdown during electroporation is a biophysical phenomenon of substantial importance to the outcome of clinical applications. It was ignored, until now. © 2015 Elsevier Inc. All rights reserved. Source
Lugnani F.,Franco Lugnani MD |
Zanconati F.,University of Trieste |
Marcuzzo T.,University of Trieste |
Bottin C.,University of Trieste |
And 8 more authors.
PLoS ONE | Year: 2015
Freezing-cryosurgery, and electrolysis-electrochemical therapy (EChT), are two important minimally invasive surgery tissue ablation technologies. Despite major advantages they also have some disadvantages. Cryosurgery cannot induce cell death at high subzero freezing temperatures and requires multiple freeze thaw cycles, while EChT requires high concentrations of electrolytic products-which makes it a lengthy procedure. Based on the observation that freezing increases the concentration of solutes (including products of electrolysis) in the frozen region and permeabilizes the cell membrane to these products, this study examines the hypothesis that there could be a synergistic effect between freezing and electrolysis in their use together for tissue ablation. Using an animal model we refer to as vivens ex vivo, which may be of value in reducing the use of animals for experiments, combined with a Hematoxylin stain of the nucleus, we show that there are clinically relevant protocols in which the cell nucleus appears intact when electrolysis and freezing are used separately but is affected by certain combinations of electrolysis and freezing. © 2015 Lugnani et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Source
Stehling M.K.,Inter Science GmbH Biophysics |
Guenther E.,Inter Science GmbH Biophysics |
Mikus P.,Inter Science GmbH Biophysics |
Klein N.,Institute fuer Bildgebende Diagnostik |
And 2 more authors.
PLoS ONE | Year: 2016
Electrolysis, electrochemotherapy with reversible electroporation, nanosecond pulsed electric fields and irreversible electroporation are valuable non-Thermal electricity based tissue ablation technologies. This paper reports results from the first large animal study of a new non-Thermal tissue ablation technology that employs "Synergistic electrolysis and electroporation" (SEE). The goal of this pre-clinical study is to expand on earlier studies with small animals and use the pig liver to establish SEE treatment parameters of clinical utility. We examined two SEE methods. One of the methods employs multiple electrochemotherapytype reversible electroporation magnitude pulses, designed in such a way that the charge delivered during the electroporation pulses generates the electrolytic products. The second SEE method combines the delivery of a small number of electrochemotherapy magnitude electroporation pulses with a low voltage electrolysis generating DC current in three different ways. We show that both methods can produce lesion with dimensions of clinical utility, without the need to inject drugs as in electrochemotherapy, faster than with conventional electrolysis and with lower electric fields than irreversible electroporation and nanosecond pulsed ablation. © 2016 Stehling et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Source


text:
Koya dance of the Koya tribe has women holding sticks fitted with brass bells that they beat on the ground while dancing. Male participants play huge drums (called Dhols) sporting turbans fitted with bison borns.
Songs and dances are an integral part of festivals of various tribes and communities all over the state.


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Since 2009, Pactimo has been providing the winners jerseys for the GGP. We are happy to keep the tradition alive, and even better, can now offer you the ability to purchase the 2016 jersey and bib-shorts directly from Pactimo's online store!
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text:
Turkey Noodle Casserole
Photo by Scott Phillips
- 1 Tbs. finely chopped fresh sage
- 1 lb. assorted fresh mushrooms, cleaned and sliced 1/8 to ¼ inch thick
- 3 Tbs. finely chopped fresh flat-leaf parsley
- 8 oz. egg pappardelle pasta
- ¾ cup coarse dry breadcrumbs
- 3 cups shredded or diced roast turkey
- 2 medium cloves garlic, minced
- + 9 more ingredients
- 2 oz. (4 Tbs.) unsalted butter; more for the baking dish
- 2 Tbs. extra-virgin olive oil
- Freshly ground black pepper
- 3-½ oz. (1-½ cups) grated sharp white Cheddar
- 1 Tbs. freshly grated Parmigiano-Reggiano
- Kosher salt
- 6 cups low-fat milk
- 2-¼ oz. (½ cup) all-purpose flour
- 3 Tbs. minced shallots
Position a rack in the center of the oven and heat the oven to 350°F. Butter a 3-quart baking dish. Bring a large pot of well-salted water to a boil over high heat. Mix the breadcrumbs, 1 Tbs. of the olive oil, Parmigiano, and sage in a small bowl. Season to taste with salt and pepper. Set aside...
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text:
Poem - What Would You like to Talk About
Talk to Me
So, if you ask me to write a poem. I will.
What would you like me to talk about?
Water, salt, fire and wind?
The greens and the blues or the life from within?
Dieing people and the life that they leave?
Clueless people living life in the breeze?
What would you like me to talk about?
Monsters that are never seen in our presence?
Santa Clause flying, distributing presents?
Love dancing before you so innocent so pure, shining in glee yet so insecure?
Let's talk behaviors and consequences or security first hand or the way the tea party is making a stand
Is it possible to hold onto the wonders of life?
How about those people who sacrifice?
I know, lets have a discussion of all the smart people, screaming for justice on top of the steeple.
The people we can trust perhaps?
The way this poam would make a good rap?
As you can see the subject's are infinite
Let's talk about it.
Pjf/pjb 1/22/11 - Copyright Protected
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