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Markets Expand for Single-Use Bioreactors
Biobags Offer Advantages Over Fixed-Tank Systems
The Challenges of Harmonizing Biomarker Data
Why Trial Success Depends on It
Top 10 Wall Street Losers of 2016
These Companies Lost the Most in a Down Year for Biopharma Stocks
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Single miRNAs Don't Say Much, but They May Become Eloquent Biomarkers if We Take Their Testimony in Context
AVI and Ercole Partner on mRNA Splicing for Genetic Disorders
AVI BioPharma and Ercole Biotech are working together to identify and develop drugs that direct the splicing of mRNA to treat a variety of genetic and acquired diseases. Under this cross-license and collaboration agreement, each party is granting the other rights under their respective patents for RNA splice-altering technologies.
Under the license agreement, AVI and Ercole will each select a set of specific gene targets to investigate the potential therapeutic effects of shifting splicing of those genes. AVI refers to its approach as Esprit (Exon Skipping Pre-RNA Interference Technology). Ercole uses the Splice Switching Oligonucleotide (SSO) in referring to its drug discovery platform to redirect mRNA splicing.
Ercole also received an exclusive license to AVI's Nuegene® third-generation antisense chemistry for the specific targets that it will select. Neugene molecules are also referred to as phosphorodiamidate morpholino oligomers (PMOs). "Our recent experiments have shown that PMOs are more effective in splice switching and up-regulation of test genes in muscle as well as heart tissues of treated mice than are a number of other chemistries we have tested," says Ryszard Kole, Ph.D., president and CSO of Ercole. "This agreement gives us access to AVI's proprietary PMO chemistry for gene targets that are of high interest to Ercole and extends the range of oligonucleotide chemistries Ercole can utilize in developing its SSO technology."
AVI will issue Ercole shares of its common stock, and Ercole will issue AVI shares of Ercole Series A-2 Preferred Stock.
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The Baths, with its Natural Hot Water Springs of 43º Celsius, is situated only two hours drive from Cape Town on a citrus farm in the scenic Olifants River Valley, near the town of Citrusdal in the Western Cape of South Africa. Established in 1739 this self-catering resort, with handsome Victorian-...
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The Radisson Blu Hotel & Residence, Cape Town will offer 339 rooms,suites & apartments in the city's central business district. Event planners love the meeting facilities that offer a sophisticated setting for hosting both personal & business events.

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Thank you for using Just Answer!
My name is ***** ***** I'll be glad to help you.
I just need to figure out exactly which model you have and then I can look up the date. Do you see any other markings on that gun (also open the cylinder and look at the areas that then become visible for more markings.
Optionally, if you can attach some photos showing both sides of the gun, that would work, too.


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We were guided by inner tube through two caves and a walk through the jungle. This young man, Chub (?) was very knowledgeable and respectful of us, as older adults and of the... read more
Charlie's Tours are very educational, ecological-oriented and adequate for...
Charlie's Tours are very educational, ecological-oriented and adequate for school kids and students of all ages.
Charlie offers an excellent ecological tour on the trails just prior to having to tube through the mysterious caves where the Maya priests once prayed to and worshiped the Gods of the Underworld.
At Charlie's Cave Tubing we cater especially to our Eco-friendly guests.
We are very serious about the conservation and preservation of the caves.
We are sure you will find this a very relaxing and pleasant experience.


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Cloud Coversingle goose down quilt
750 fill power hydrophobic goose down quilt. A lightweight and versatile alternative to a full sleeping bag
Cloud Cover single goose down quilt
For ultralight travel (and pure snuggability) a down camping blanket is a versatile piece of kit.
But that's not to say you should take your 50 kg duvet from home! Cloud Cover down quilt is made with a lightweight construction and a 200 g fill to keep you cosy in summer months and warmer climes or coupled with a beefier bag for ultimate-winter warmth.
The fill is 750 IDFB hydrophobic goosedown which means that it retains its loft better in damp conditions than untreated down. The corner attachments allow Cloud Cover to be mated with another quilt* or attached to itself to create a more traditional sleeping bag shape. A drawcord on either end can be tightened to keep the warmth in when the temperature drops.
With no zip, hood or foot section to speak of it is no surprise this is one of the lightest options you can find. Perfect for use in vans and as an emergency blanket to keep in the boot of your car.
Stays dry and retains loft up to 60 times longer than untreated down. It's water based formulation is PFC-free and will not harm you or the environment. Absorbs 90% less water than untreated down, restoring performance much quicker.
The down we use in Could Cover is certified RDS (Responsible Down Standard). This mark indicates that the down in this product does not come from birds that have been live-plucked or force-fed, and that their welfare has been protected from the time they were hatchlings to when they are slaughtered. That's good to know.
Key features
- 750 IDFB 90/10 chinese goosedown fill
- RDS (Responsible Down Standard) sourced down - Ethically sourced, not live-plucked and not force-fed
- Nikwax Hydrophobic fluorocarbon free water resistant down
- Draw cord at either end of quilt
More images
Vital stats
Fill: 90/10 Chinese white goose down
Weight: 520 g
Fill power: IDFB 750
RDS certified
Nikwax Hydrophobic
Length: 180 cm
Width top: 130 cm
Width bottom: 95 cm
Baffles: 12
Stitch-through construction
Packed size: 270 x 195 x 65 mm
20 D Polyester, 45 g/m2
Origin: China
It is not possible to give this product a temperature rating in the same way we can with our sleeping bags. Generally we would recommend its use during the summer months, or as an extra layer of insulation in the winter.
Same day despatchAll orders received before 2pm despatched same day.
Free UK Shipping on all ordersFree 2 day delivery to UK addresses is included in all orders so the price you see is the price you pay. Upgrade to next day at the checkout.
Free No hassle 123 Day ReturnsBuy with confidence and if you are not happy, change your mind or want a swap for any reason then return it for free and we will exchange or refund no question. The price you see is the price you pay. Just return the kit as you receive it - in its original condition, unused, unworn, with original packaging and fit for resale.
FinanceWe offer a range of finance options from 0% to 9.9% starting on orders over £500. Please give us a call on 01773 417007 to apply for finance. Our customer support heros will take your order and talk you through the quick and easy application process.
Alpine BondIf one of our products does not meet your expectations upon delivery or, if it does not live up to the demands placed upon it, please return it within 3 years of purchase for repair, replacement or refund. If the problem is our fault then we will do this to your satisfaction if it's your fault then we will help out the best we can.
Support - There are five ways to get in touch
- Visit the Support Department section
- Email us at firstname.lastname@example.com
- Ring us on 0044 1773 417 007
- Write to us here
- Drop by our Factory Store : Open Mon-Fri 9am to 5.30pm
Related content
Related products
Synthetic sleeping bag£60.00
Ultra lightweight 545 g goose down sleeping bag£140.00
-48ºC goose down sleeping bag for extreme conditions£435.00
Primaloft synthetic sleeping bag£80.00
Goosedown all season sleeping bag weighing 1kg£250.00
10 Reviews
Used this product?Write a review
A great option for boosting your existing bag
Used this over a winter weekend in the Lakes to boost my 3 season bag. Worked a treat. What more can you say really, oh yes I think at the price of 100 smackers this is great value . No idea if the hydrophobic bit actually made any difference, I was warm that is all that matters.
A good liner option!
I used this last night in -2C as an extra liner inside a 3-season bag. Being February, I needed to beef up my go to sleeping bag (PHD Minim 400) without buying a completely new 4-season bag. Using this as a liner quilt works very well and it adds a season. The press studs allowed me to enclose my body warmth inside effectively and they didn't pop open during the night.
I am very tall (6ft 4), and the cover did not span the length of my body. I don't mind this - actually I am used to gear heightism, so I used a down jacket for my top half as I normally do and thick socks for my toes.
I also looked at the point-5 quilt by Alpkit, but I think this is more versatile due to it being able to be laid out flat like a proper quilt. If used alone the extra long draw strings could be used to tie under a sleeping mat, meaning you have a fixed down layer over you that is non-restrictive.
I am not sure how much warmth it would give on its own. Perhaps only suitable for very warm summer's night, or indoors use. But certainly an ideal solution as a liner inside another bag during Winter.
Superb kit, for bag, house or car...
I wanted an alternative to a sleeping bag to keep in my car for emergencies. This Cloud Cover quilt fit the bill perfectly.
It folds down to a really small package, which means its virtually hidden away in the boot, or even used as cushion. However, when its open its a great size to either use as a full blanket, or folded in half as a car blanket over someone's knees at the start of a cold journey.
(Its used regularly and not just kept for emergencies)
It feels really good quality and is so lightweight, yet amazingly warm.
It IS expensive at £99, but it'll save your bacon one day and you'll be thankful of it i'm sure.
You'll not be disappointed.
good decision
Decided to take a punt on a quilt as I struggle to get a good nights sleep in my mummy bag any more as I get older. The cloud cover is definitely the way forward for me. Much warmer than its light weight suggests and lets me splay and roll about in comfort. I tested it with a cheap summer duvet this winter and was toasty. I reckon 2 quilts doubled up would be good for most seasons and give real versatility. Good stuff
Top notch
A great bit of kit. Really light, packs down tiny and warmer than you think it's going to be. Perfect for summer adventures.
Popper issue
I own a black Cloud Cover and I subscribe to all the praise written by the previous reviewers. However, I think the use of poppers in combination with the lightweight fabric is a bit unfortunate. From the moment I got the quilt I was always very careful when unfastening the poppers because I thought they might get easily torn out. But a few days ago it took me just a moment of not being careful enough and I managed to tear one of the poppers out, with a lot of down flying out of the holes on both sides of the quilt.
Best bit of kit in my rucksack. £ 4 lb best value and performance.
Perfect for a hammock
Have had my cloud cover for a few weeks now and couldn't be happier. I have used it a couple of times in my hammock now and am hoping for lots more chances to do so, the cloud cover is the perfect thing for in a hammock easy to get in and out of, keeps you more than warm enough and is a fraction of the price of a branded hammock blanket. Thanks for providing such great products alpkit
Warm and light
Had a minor issue with the cloud cover Alpkit sorted it out in no time, used this bad boy in the lakes at 2000ft in a bivi bag it kept me nice and warm despite the cold wet/windy weather. I really like the weight as it its so light.One thing that I really like is that when Alpkit states the weight of an item it is usually spot on. Nice one guys
Versatile must have
I had this as a Christmas present and I've used it loads since. The best thing about it is how versatile it is and I think I've only just scratched the surface. I've used it as insulation inside a bivvy bag in the spring, inside a slight sleeping bag in the winter, as a blanket on the beach, in a train, on the sofa at home, I've even worn it as a long coat! It packs down really really small, is ultra light and warmer than your would expect.
Cloud Cover quilt first look
Stuart takes a look at the Cloud Cover a 650+ fill down quilt
Sixty five quid! £65 is an almost ridiculously small amount of money to pay when you consider what you're actually getting.
Bear Bones Bikepacking December 2015 - Stuart Wright


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