text:
Increased T regulatory cells and decreased Th1 pro-inflammatory cytokines correlate with culture-positive infection in febrile neutropenia childhood oncology patients
Hodge G.,SA Pathology |
Scott J.,SA Pathology |
Osborn M.,SA Pathology |
To L.B.,SA Pathology |
And 3 more authors.
Cytokine | Year: 2011
Background: Paediatric oncology patients with febrile neutropenia are usually hospitalised and treated with empirical broad-spectrum antibiotic therapy to counter the risk of infection. However, there is currently no method available to rapidly identify bacteremia in these patients. T-helper-type-1 (Th1) cytokines are required for effective immune response to many pathogenic organisms and T regulatory cells are known suppressors of Th1 cells. We hypothesized that characterization of reduced intracellular Th1 cytokines and increased T regulatory cells (Tregs) may prove useful in identifying infection in childhood oncology patients with febrile neutropenia. Methods: Intracellular Th 1 cytokines and Tregs were enumerated in peripheral blood from a group of childhood oncology patients with febrile neutropenia using multiparameter flow cytometry. Results: There was a significant increase in the percentage of CD25+ CD127- CD8- CD3+ Tregs and a significant decrease in Th1 intracellular cytokines IFNγ, IL-2 and TNFα in the blood of culture positive patients compared with culture negative patients. Conclusions: Enumeration of Tregs and intracellular Th1 cytokines may provide a sensitive, specific test for determining infection in childhood oncology patients before blood culture results become available. © 2010. Source
Davenport M.H.,R Samuel Mclaughlin Foundation Exercise And Pregnancy Laboratory |
Goswami R.,Neurovascular Research Laboratory |
Kevin Shoemaker J.,Neurovascular Research Laboratory |
Mottola M.F.,R Samuel Mclaughlin Foundation Exercise And Pregnancy Laboratory |
And 2 more authors.
American Journal of Physiology - Regulatory Integrative and Comparative Physiology | Year: 2012
Endothelial dysfunction is commonly observed in women with a previous diagnosis of gestational diabetes mellitus (GDM). Whether arterial stiffness is also related to pregnancy and/or postpartum glucose intolerance has not been determined. We examined the influence of GDM during pregnancy and hyperglycemia in the postpartum period on arterial function. Thirty postpartum women were stratified into one of three groups: 1) normoglycemic pregnancy, normoglycemic postpartum (NORM), 2) GDM during pregnancy, normoglycemic postpartum (GDM-N); and 3) GDM during pregnancy, hyperglycemic postpartum (GDM-H). Ten never-pregnant controls were also recruited (Control). All measures were made at 2 mo postpartum or in the early follicular phase in Control women. Arterial stiffness was assessed by pulse wave velocity (PWV) and brachial and carotid artery distensibility. Endothelial function was determined by flowmediated dilation (FMD). PWV was not different between the four groups. Distensibility of the brachial and carotid arteries was lower in GDM-N women (brachial: 1.1 X 10 -3 mmHg -1 ± 3.6 × 10 -4; carotid: 2.0 X 10 -3 ± 3.3 × 10 -4) and GDM-H (brachial: 1.4 × 10 -3 mmHg-1 ± 4.1 × 10 -4; carotid: 1.8 × 10 -3 mmHg -1 ± 5.0 × 10 -4) compared with NORM women (brachial: 3.4 × 10 -3 mmHg -1 ± 7.0 × 10 -4; carotid: 3.9 × 10 -3 ± 7.4 × 10 -4). However, only brachial artery distensibility returned to Control levels by 2 mo postpartum in the NORM women. FMD was lower in previously GDM women (GDM-N: 4.1% ± 2.3; GDM-H: 4.4% ± 0.9) compared with NORM women (10.8% ± 1.3; P < 0.01). These findings suggest that the vascular function of women in the early postpartum period is influenced by GDM during pregnancy and the persistence of clinical and/or subclinical hyperglycemia after delivery. © 2012 the American Physiological Society. Source
The vent-like homeobox gene VENTX promotes human myeloid differentiation and is highly expressed in acute myeloid leukemia
Rawat V.P.S.,University of Ulm |
Arseni N.,Helmholtz Center Munich |
Arseni N.,Ludwig Maximilians University of Munich |
Ahmed F.,Helmholtz Center Munich |
And 15 more authors.
Proceedings of the National Academy of Sciences of the United States of America | Year: 2010
Recent data indicate that a variety of regulatory molecules active in embryonic development may also play a role in the regulation of early hematopoiesis. Here we report that the human Vent-like homeobox gene VENTX, a putative homolog of the Xenopus xvent2 gene, is a unique regulatory hematopoietic gene that is aberrantly expressed in CD34+ leukemic stem-cell candidates in human acute myeloid leukemia (AML). Quantitative RT-PCR documented expression of the gene in lineage positive hematopoietic subpopulations, with the highest expression in CD33+ myeloid cells. Notably, expression levels of VENTX were negligible in normal CD34 +/CD38- or CD34+ human progenitor cells. In contrast to this, leukemic CD34+/CD38- cells from AML patients with translocation t(8,21) and normal karyotype displayed aberrantly high expression of VENTX. Gene expression and pathway analysis demonstrated that in normal CD34+ cells enforced expression of VENTX initiates genes associated with myeloid development and down-regulates genes involved in early lymphoid development. Functional analyses confirmed that aberrant expression of VENTX in normal CD34+ human progenitor cells perturbs normal hematopoietic development, promoting generation of myeloid cells and impairing generation of lymphoid cells in vitro and in vivo. Stable knockdown of VENTX expression inhibited the proliferation of human AML cell lines. Taken together, these data extend our insights into the function of embryonic mesodermal factors in human postnatal hematopoiesis and indicate a role for VENTX in normal and malignant myelopoiesis. Source
Elevated serum cytokine levels using cytometric bead arrays predict culture-positive infections in childhood oncology patients with febrile neutropenia
Badurdeen S.,Child Health Research Institute |
Hodge G.,SA Pathology at Womens and Childrens Hospital |
Osborn M.,SA Pathology at Womens and Childrens Hospital |
Scott J.,SA Pathology at Womens and Childrens Hospital |
And 4 more authors.
Journal of Pediatric Hematology/Oncology | Year: 2012
Neutropenic patients with bacteraemia need prolonged intravenous antibiotic treatment. Using cytometric bead array technology, we show in children with febrile neutropenia that bacteraemia is associated with an elevation of at least 1 of 3 plasma cytokines plus C-reactive protein. The combination of interleukin (IL)-8, IL-6, IL-10, and C-reactive protein values above operator-defined cutoff levels identified 15 of 16 episodes of bacteraemia, making this a potentially useful technique in identifying high-risk patients who should not be discharged early from hospital. Furthermore, low risk of bacteraemia may be predicted by a combination of below threshold cytokines and negative clinical examination. Copyright © 2011 by Lippincott Williams & Wilkins. Source
News Article
Site: http://www.biosciencetechnology.com/rss-feeds/all/rss.xml/all
In his role as a pediatrician, Manish Butte, M.D., Ph.D., will often push and prod a patient's abdomen, feeling for abnormalities — a swollen spleen, a hardened lymph node or an unusual lump in the intestines or liver. There are still some things that can only be gleaned by touch, and Butte believes this notion applies to individual cells as well. Yet researchers' ability to probe and measure the features of living cells has been almost nonexistent. Recently, a team of Stanford scientists and engineers set out to right that imbalance with a new technique for rapidly mapping cells. They succeeded by engineering a major advancement in a technology known as atomic force microscopy, or AFM, which itself was invented at Stanford in 1986. A paper describing the work was published online Nov. 11 in ACS Nano. Butte, an assistant professor of pediatric immunology, is the senior author. Lead authorship is shared by Andrew Wang, Ph.D., a former postdoctoral scholar in Butte's lab, and Karthik Vijayrhagavan, Ph.D., who was a graduate student and member of the microphotonics lab led by Olav Solgaard, Ph.D., a professor of electrical engineering. "What a cell feels like — its mechanical properties that affect how it makes contact with other cells and tissues — is much more important than what it looks like, but the technology just wasn't there to allow us to examine it," Butte said. "There is a lot to be learned from studying the mechanics of a cell and its structures just beneath the surface." The way Butte and his colleagues use AFM to measure the mechanical properties of cells is akin to the way a builder taps her knuckles along a drywall, listening for the change in pitch that will tell her a wooden stud is on the other side. When an AFM probe taps the surface of a cell, it vibrates, and the pattern of these vibrations, like the sound waves reflecting from the stud, gives mechanical information about the structures of the cell being touched. However, existing AFM probes are relatively large and, as a result, insensitive to high frequencies, which communicate much of the key information about a cell's innards. The Stanford team's device couples a very small probe with a traditional one. This assembly allows the device to sense faster oscillations than conventional devices and, accordingly, to take more detailed and much faster measurements. "The main difference between this and previous atomic force microscopes is that we are able to measure the impact of the probe on the cell very fast and get specific readings, whereas typical AFMs simply provide an average. This allows us to accurately measure some very soft materials for the first time," said Solgaard, who also is a co-author of the paper. Current probes measure cellular stiffness by tapping against the cell around one or two times per second — the fastest that the large probes can make measurements. The small probe, however, can make detailed measurements easily at five to 10,000 taps per second because of its sensitivity. He likened the leap in sensitivity to the difference between driving a Cadillac Escalade down the road and pushing a Hot Wheel toy car along the same surface: "The small Hot Wheel will feel every little bump so much more than the large Cadillac." AFMs measure movement of the probe by bouncing a laser off its tip. As the tip moves up and down, the laser is reflected. The Stanford invention couples the small probe with the large one by means of a fork-shaped structure called an interferometric grating. The grating produces a diffraction pattern based on the movements of the small probe, and allows the AFM to conveniently capture its measurements. "Our tip actually produces a second signal, and that is what allows us to get much greater detail. From an engineering standpoint, it's an extremely simple, beautiful solution," Solgaard said, referring to the diffracted signals from the grating. Best of all, the team's device can be directly attached to existing AFMs, potentially saving millions of dollars on new equipment that could otherwise be spent on research. A new AFM can run as much as $500,000, according to Solgaard. The objective is the cellular equivalent of Butte pressing a child's abdomen. "We want to study cell stiffness to understand what is beneath the surface and how cells are structured," Wang said. As a demonstration, the team measured a section of a red blood cell, making approximately 4 million total measurements in about 10 minutes — all without damaging the delicate cellular exterior. "The same measurements would have taken more than a month to complete using conventional atomic force microscopes," said Vijayraghavan. The technology is so fast that the team was able to create a series of time-lapse images of a living cell, each taken just seven minutes apart, a previously unimaginable pace. The practical applications of the device range from basic scientific understanding of cellular structure to immunology and oncology. Scientific understanding of the mechanical forces at play in cells is so lacking that the field — now being called mechanobiology — is really in its infancy, according to Butte. The mechanical forces in the body can come from tissues, which range in stiffness from softest brain matter to stiffest bones, from gravity, and even from the pushing and pulling movements of other cells. Cancer cells make their environment mechanically rigid by secreting chemicals that stiffen up the extracellular matrix. Cancer cells likewise interpret the mechanical forces of a tissue to make decisions about growth and metastasis. Surprising feedback loops like this also appear to occur for stem cells in the bone marrow and during embryonic development. How immune cells interpret mechanical forces is still totally unknown. "The lowest-hanging fruit is cancer. Cancers are often stiffer than normal, healthy tissues and we can use that knowledge to diagnose disease. But first, you have to have good data, which our device provides," Wang said. He has already used an early form of the new Stanford probe in pilot work on breast cancer specimens taken from mastectomies. For his part, Butte plans to use fast AFM to study the immune system. He hopes to explore why otherwise disease-fighting T cells often remain dormant once inside a tumor. He theorizes that the mechanical stiffness of the tumorous tissue may be preventing T cells from freely making contact with cancer cells and from triggering their cancer-fighting functions. In essence, the tumor may be too crowded for the T cells to work. On the other end of the stiffness gamut, he believes that the soft mechanical properties of chronically inflamed or infected tissues provoke the immune system into over-activity, like autoimmunity. It is a theory no one has yet explored due to technical barriers, which the fast AFM could overcome. Butte's lab has begun a broad effort to link mechanical forces with immune responses at the molecular, cellular and tissue scales. "There is so much we don't know about the mechanical properties of various cell types and diseased tissues. Almost nothing, in fact," Butte said. "The first step is to probe. Now, we can do that." The work was funded by the National Institutes of Health, the National Science Foundation, the Stanford Center for Probing the Nanoscale, the Stanford Child Health Research Institute and Stanford Bio-X.


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An extensive epidemic of diarrhea due to Escherichia coli O111:B4 (EEC) occurred during the winter of 1960-1961 in the metropolitan Chicago-Northwest Indiana region. In the July, 1962, issue of American Journal of Hygiene, Kessner, Shaughnessy, and seven other public health workers1 report the visible portion of the epidemic iceberg which involved over 1,300 children and 29 community hospitals over a period of 9 months. The over-all mortality rate was nearly 6%. Theirs is a horrid tale of a community whose doctors generally didn't believe in the importance of EEC. Theirs is a tale of the largest community outbreak of infantile diarrhea reported in the space age. Imagine an epidemic of infants with an age specific attack rate of 3,700 per 100,000 in a metropolitan area like South Chicago. The public used to panic at milder figures from polio.
This was a nosocomial epidemic (nosos—disease + komein—to take care
W.E.W . Where Is Our Nosocomial Conscience?. Am J Dis Child. 1962;104(6):593-594. doi:10.1001/archpedi.1962.02080030593001
© 2017

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In the Caribbean, Sustainable Tourism is understood as the optimal use of natural, cultural, social and financial resources for national development on an equitable and self sustaining basis to provide a unique visitor experience and an improved quality of life through partnerships among government, the private sector and communities. This section contains documents, reports and studies related to research or projects on sustainable tourism development, at both regional and international levels.
Caribbean Excellence in Sustainable Tourism Awards 2016
These CTO Awards are aimed at identifying and showcasing Sustainable Tourism Good Practices in the Caribbean. The awards recognize individuals, groups, organizations or companies in any of the Caribbean Tourism Organization (CTO) Member Countries which have developed responsible and unique tourism products or are engaged in implementing sustainable tourism-related initiatives which embrace sustainable tourism concepts and core values. These initiatives should also help to enhance the country's tourism product offerings and advance sustainable and responsible tourism in the Caribbean. Read more: CTO CEST Awards
Sargassum and the Effects of Climate Change
View presentation by Kelly de Schaun, Executive Director, Galveston Island Park Board of Trustees and CVB, who is responsible for the maintenance of 32 miles of beaches and seven major beach parks: https://drive.google.com/file/d/0B5SMN7hmRwhzTl93LTBkMTRZeHc/view
Sargassum Resource Guide
The Guide is intended to serve as an initial resource for the Caribbean, in particular to inform the tourism industry, local governments, environmental groups and residents about Sargassum seaweed, its impact and uses, and best practice mitigation and management measures which are being undertaken. Provided this is a new and natural occurrence, there are ongoing studies on the tracking, use, effects and mitigation of Sargassum seaweed. The following pages seek to provide additional information to further educate the tourism sector and other stakeholders.
- Caribbean Conference on Sustainable Tourism Development (STC)
The Caribbean Tourism Organization has been staging its Annual Conference on Sustainable Tourism Development, otherwise known as the Sustainable Tourism Conference (STC) since 1997. This Conference is part of the information dissemination and regional awareness component of CTO's Strategy for Sustainable Tourism and examines how member states can design and implement sustainable tourism policies and programs, offering a regional forum for information exchange on the successes and pitfalls of national, regional and international initiatives.
View conference proceedings on the conference website: http://www.caribbeanstc.com
- Sustainable Destinations Alliance for the Americas (SDAA)
SDAA website: http://sustainabletravel.org/sdaa/
The Caribbean Tourism Organization (CTO), the Organization of American States (OAS), Sustainable Travel International, Royal Caribbean Cruises Limited, and the US Permanent Mission to the Organization of American States launched the Sustainable Destinations Alliance for the Americas (SDAA) in March 2014.
The SDAA aims at ensuring that tourism within the Caribbean and Central America regions continues to prosper and achieves the quality necessary to compete effectively with other international destinations by promoting sustainable destination management. View video: http://travelmole.tv/watch_vdo.php?sid=1&id=16116
Sustainable Destinations Alliance of the Americas from Sustainable Travel International on Vimeo.
For more information on SDAA, visit: http://sustainabletravel.org/our-work/solutions-for-destinations/regional-alliances/sdaa/
Gail Henry, former (CTO) Sustainable Tourism Product Specialist, spoke with TravelMole Publisher about SDAA: http://travelmole.tv/watch_vdo.php?sid=1&id=16116
- International Renewable Energy Agency (IRENA)
The International Renewable Energy Agency (IRENA) Event on Renewable Energy Application for Island Tourism presentations: http://www.irena.org/menu/index.aspx?mnu=Subcat&PriMenuID=30&CatID=79&SubcatID=429
- CTO CARPHA Regional Tourism Health Programme
CARPHA and CTO Launch Tourism and Health Programme in the Region
In 2014, CARPHA and CTO launched a Regional Tourism and Health Programme geared at strengthening the links between tourism, health and environment for more resilient and sustainable tourism in the Caribbean.
View full CARPHA media release on launch: http://carpha.org/articles/ID/16/CARPHA-and-CTO-Launch-Tourism-and-Health-Programme
- IDB Disaster Risk Management CCA
Regional Monitoring and Evaluation System for Disaster Risk Management and Climate Change Adaptation in the Tourism Sector (IDB DRM CCA)
The Inter-American Development Bank (IDB) and the Caribbean Disaster Emergency Management Agency (CDEMA), in April 2010, formalized the terms of a US$ 750,000 grant that supports the Regional Monitoring and Evaluation System for Disaster Risk Reduction and Climate Change Adaptation in the Caribbean Tourism Sector Project.
The project's goal is the reduction in vulnerability of the Caribbean tourism sector to natural hazards and disasters, including associated adaptive capacity for climate variability and climate change. The executing agency is the Caribbean Disaster Emergency Management Agency (CDEMA).
August 2012 : The First Regional Meeting
The Inter-American Development Bank (IDB) sponsored project "Regional Monitoring and Evaluation System for Disaster Risk Management and Climate Change Adaptation in the Caribbean Tourism Sector" reached a milestone on August 8-9, 2012 when the Executing Agency, the Caribbean Disaster Emergency Management Agency (CDEMA) convened the First Regional Meeting at the Pegasus Hotel, Kingston Jamaica.
The objectives of the meeting were to discuss and recommend for endorsement the outputs of Component 1 of the project, "Development of the Regional Monitoring and Evaluation (M&E) Framework". Specifically, two main sub components were reviewed and discussed they were the Revised Regional DRM Strategy and Action Plan which incorporates CCA and the outputs from the national stakeholder meetings.
The regional meeting also facilitated the face to face meetings of the arms of the project's governance structure, these are the National Focal Points (NFP), the Board of Management (BM) and the Technical Advisory Committee (TAC).
The success of the meeting was demonstrated by the general support for the Draft Revised Regional Disaster Risk Management and Climate Change Adaptation Strategy and Plan of Action for the Tourism Sector in the Caribbean and the enthusiasm with which information, comments and suggestions were exchanged. Representatives from the participating states, the Caribbean Tourism Organization (CTO), the Caribbean Community Climate Change Centre (CCCCC), the Inter American Development Bank and the CDEMA CU agreed in principle with the revised draft (SAP).
The next steps include the finalization of the SAP and the movement towards national level adaptation.
July 2012: The SAP
The "Regional Disaster Risk Management Strategy and Plan of Action for the Tourism Sector in the Caribbean" (SAP) developed under the IDB sponsored "Regional Disaster Risk Management for Sustainable Tourism in the Caribbean" project is currently being reviewed specifically to incorporate climate change adaptation. This is part on the ongoing IDB sponsored project "Regional Monitoring and Evaluation System for Disaster Risk Management and Climate Change Adaptation in the Caribbean Tourism Sector".
The main idea of the SAP is to create a strategic framework by which the countries of the region can support tourism amidst natural hazards and climate change. If well adapted into the national development programme, the SAP creates the foundation on which the monitoring and evaluation system can be built.
"The purpose of the Regional DRM and CCA Strategy for the Tourism Sector (SAP) is to reduce the vulnerability of the Tourism sector to natural hazards and climate change through integrating/ mainstreaming comprehensive disaster management and climate change adaptation. The Strategy identifies Regional Strategic Objectives (RSOs) and key activities for the Caribbean Tourism sector.
The Plan of Action details those measures that can be undertaken by Tourism stakeholders at the regional and national levels to meet the RSOs. To fully attain the RSOs, measures are required to be undertaken by stakeholders who are bound by national parameters. Therefore, to be a fully effective instrument, the Regional Strategy and Plan of Action are dependent on National Strategies and Plans of Action for the Tourism sector," the Draft Revised Regional Disaster Risk Management and Climate Change Adaptation Strategy and Plan of Action" pg 12, 2012.
Therefore, the adaptation of the SAP at the national level as a policy approach to DRM and CCA in the tourism sector is fundamental for progress and sustainability.
In a review of the SAP critical climate change issues such as, rising sea levels (0.36 to 2.5 ft), altered patterns of agriculture, increased extreme weather events, the expansion of the range of tropical diseases among others were the topics for discussion. Specific measures to either adapt or mitigate were also considered in order to ensure that the SAP provides the required framework for improvement. Current initiatives undertaken by Caribbean countries were captured in order to gauge the challenges, successes, risks and implications. In this way the SAP becomes a tool that encapsulates the reality of adaptation to climate change and managing natural hazards in the Caribbean.
Further information on the Draft Revised Regional Disaster Risk Management and Climate Change Adaptation Strategy and Plan of Action can be obtained from the CDEMA CU: [email protected] Details on the process of review will be provided in subsequent articles.
CARIBSAVE is a partnership between the Caribbean Community Climate Change Centre (CCCCC) and the University of Oxford. The CARIBSAVE Partnership addresses the impacts and challenges surrounding climate change, tourism, the environment, economic development and community livelihoods across the Caribbean Basin, using an integrated and holistic approach.
Visit the CARIBSAVE website: http://caribsave.org/
View report: CARIBSAVE Seed Funding Project ~ Caribbean Climate Change, Tourism and Livelihoods: A sectoral approach to vulnerability and resilience.
View paper: CARIBSAVE Partnership & Climate Change ~ Dr. Murray Simpson, CEO CARIBSAVE Partnership
View the CARIBSAVE Partnerships for Resilience climate change film series.
The Caribbean is the most tourism-dependent region in the world with few options to develop alternative economic sectors. The region is one of the most vulnerable in the Map of Caribbean world to the impacts of climate change including sea level rise, biodiversity loss and impacts on human health.
The CARIBSAVE partnership is providing practical strategies, and implementing capacity building and skills transfer activities across the region for pro-poor and national economic development in the Caribbean in an era of economic restructuring and climate change.
CTO is a partner of this project.
- Caribbean Hotel Energy Efficiency Action Programme
The US$2 million Caribbean Hotel Energy Efficiency Action Programme (CHENACT) is meant to drive the Caribbean hotels to implement energy efficient practices and to generate their own renewable energy. This, in turn, is expected to improve their competitiveness through improved energy use.
The region's public and private sector tourism groupings, the Caribbean Tourism Organization (CTO) and the Caribbean Hotel & Tourism Association (CHTA) – through its environmental arm, the Caribbean Alliance for Sustainable Tourism (CAST) – have launched a 24-month project to help the Caribbean hotel sector move towards energy efficiency.
One of the main components is the design and preparation of the energy efficiency programme and institutional strengthening. Using Barbados as a case study, this component involves performing detailed energy audits and understanding energy consumption patterns among Caribbean hotels.
Other key components include support for the preparation of policy in energy efficiency for the tourism sector; assessing Caribbean energy service companies and their potential to service the tourism sector; and energy consumption surveys. The CHENACT project was conceptualized by the Inter-American Development Bank (IDB), which is contributing US$1 million to the budget, with the remainder coming from a number of participating agencies and the government of Barbados.
The CTO will be the executing agency, while CAST will implement the project.
In seeking its goal of achieving higher energy efficiency, the project will also explore the possibilities of obtaining carbon credits for reduced carbon dioxide emissions through the Clean Development Mechanism (CDM) of the United Nations Framework Convention for Climate Change (UNFCCC).
Synergies have also been constructed within the CHENACT project with the United Nations Environmental Programme (UNEP), ensuring compliance among the participants to both the Kyoto Protocol by reducing carbon emissions, and the Montreal Protocol, in relation to the phasing out of ozone depleting substances (ODS) in air conditioning and refrigeration equipment.
The ultimate goal of this project is to make the CHENACT participants eligible for the Climate Investment Fund (CIF) managed by the World Bank and regional banks such as the IDB for very soft for programs that can show transformation towards a low carbon foot print. This fund (approximately US$5 billion) could be used for the financing and final implementation of relevant projects.
Other international agencies collaborating with CHTA and CTO on this initiative include:
- German Technical Cooperation (GTZ)
- Centre for Development Enterprise (CDE) based in Brussels
- Inter American Development Bank (IDB) through the Sustainable Energy and Climate Change Initiative (SECCI)
- United Nations Environment Programme (UNDP)
For more information on CHENACT, contact:
Loreto Duffy-Mayers
CHENACT Project Manager
CHTA Office -4th Avenue Belleville
St. Michael, Barbados
Tel: 246-4350847, Fax: 246 -4350845
E-mail: [email protected]
Energizing the Caribbean Hotel Industry ~ Gail Henry; Sustainable Tourism Product Specialist, CTO – World Tourism Day 27th September, 2012, Barbados
CHENACT Presentations
Caribbean Hotel Energy Efficiency Action Program (CHENACT) Presentation, March 30, 2012
Save the Planet, Save Your Money: Cutting Costs Through Responsible Resource Use ~ Bill Meade, TetraTech
What is CHENACT?~ Loretta Duffy-Mayers
Caribbean Hotel Energy Efficiency Action Program ~ Loretta Duffy-Mayers, October 2010
March 2010 CHENACT Hotel Clean Energy Training Workshop Presentations
New Rate Structure – Encouraging greater efficiency ~ Stephen Worme, Barbados Light and Power
How Can CHENACT Help Barbados Hotels? ~ Loretta Duffy-Mayers
Ozone Depleting Substances ~ Grantley N Parris MASHRAE, MIstR
Energy Efficiency Opportunities for Caribbean Hotels ~ Andre Escalente
- UNEP CTO Caribbean High Level Sustainable Tourism Symposium Project
The overall objective of this UNEP-CTO project is to assess CTO member country sustainable tourism-related priority needs and current and past institutional sustainable tourism programming and investment. A participatory high-level regional Symposium and consultation process to discuss identified needs took place in October 2012.
The STPS has provided additional support to IUCN, Switzerland by distributing its 2012 publications:
Biodiversity: My Hotel in Action – A guide to the sustainable use of biological resources in the Caribbean
Biodiversity: My Hotel in Action – Hotel Manager's Checklist
Siting and Design of Hotels and Resorts – Principles and Case Studies for Biodiversity Conservation
- Agro and Culinary Tourism Product Development
Under the OAS-funded "Gastronomic Product Development and Promotion for Caribbean Destinations – Developing the Tourism Industry Human Resources", an introductory workshop on agro and culinary tourism took place at STC-13 in Guyana.
View Presentation by Ena Harvey, IICA
The project's overall objective is to build the capacity of Caribbean tourism agencies to enhance their culinary tourism product development and marketing efforts and to strengthen the linkages between culinary tourism and the agro, cultural and heritage tourism niches. This project will seek to build on the results of the (CTO, CARICOM Secretariat, IICA, OAS and Government of Barbados supported) agrotourism workshop which took place in Barbados from 19-22 September, 2011. The regional agrotourism strategy which emanated from it is being fine-tuned.


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See what's happening at Aviva, and get involved.
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Back at Bellator 135, LC Davis showed the heart of a champion in his "fight of the year" candidate fight against Hideo Tokoro! watch video >>
At Bellator 125 hard hitting Brazilian Rafael Carvahlo made a huge statement after knocking out tough middleweight Brian Rogers! Subscribe for more great Bellator MMA content! http://bit.ly/Subscrib watch video >>
Going into hostile territory, Patricky Pitbull showed he could come out on top in David Rickels' home town. Jimmy Smith Breaks it down! Bellator 141, August 28th live and free on Spike 9/8c! watch video >>
Saad Awad was tested with a ferocious punch from Jon Duarte, but showed unbelievable resiliency to get the win. Jimmy Smith breaks it down. watch video >>
Back at Bellator 126, Brandon Girtz made quick work of Benny Madrid clocking in his first TKO win. Brandon Girtz fights Melvin Guillard at Bellator 141, August 28th live & free on Spike 9/8c watch video >>
Melvin Manhoef debuted back at Bellator 127, the result...complete domination. Watch Manhoef return against Hisaki Kato this Friday on Spike 9/8c watch video >>
Staying focused is the key to any great fighter's game plan. Raphael Butler showed his focus to stay on top of a difficult submission, such as the standing guillotine choke he used versus Josh Diekma watch video >>
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When he first entered MMA, Justin Wren was considered one of the hottest prospects at the time. He left the sport to pursue his interests in making the world a better place. Wren has returned to the watch video >>
With eleven of his twenty victories coming from submission, his KO win over Ryan Healy proved that Marcin Held's game has tremendous upside. Jimmy Smith Breaks it all down. Held returns agains Tiger watch video >>


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|Tipo de imóvel
|Estadia Mínima
|3 - 7 noites
Você pode ter seu bolo e comê-lo também neste condomínio isolada verdadeiramente à beira-mar na West Bay Beach. No prazo de 25 pés de borda da água você pode assistir para o flash esmeralda no conforto do ar condicionado, enquanto você está misturando um macaco Lala. Ou assistir a sua família vêm e vão no barco de mergulho ao lado.
Esta segunda casa está bem equipado para férias gozo quaisquer das famílias. A suíte master com cama king size é separado do segundo quarto via corredor de largura e segundo banho. Uma cama de casal e uma cama de solteiro compõem o segundo quarto. Há dois sofás bem feitas camas queen na sala de estar.
Cada quarto tem ar condicionado que são montados teto com ventiladores de teto com controle remoto. As grandes sliders selecionados pode ser aberta para deixar entrar a brisa do oceano. Esta unidade está ligado a gerador de backup do desenvolvimento que é ativado automaticamente quando o poder sai.
Ao lado do pequeno desenvolvimento condomínio de 6 unidades é um pequeno e tranquilo resort de mergulho e, por outro lado é uma grande propriedade da família. Este desenvolvimento é apenas uma curta caminhada para os principais resorts e restaurantes em West Bay Beach ainda é isolado a partir deles via o ponto de costa ferro curto. Existem apenas estradas privadas ao longo desta parte da West Bay Beach fornecendo acesso aos residentes e convidados apenas.
Há amplo resorts de mergulho, restaurantes, bares e lojas a cerca de 10 minutos a pé da vila por isso não há necessidade de ter um carro de carro para West End para a vida noturna. No entanto, você está protegido da confusão, agitação e do barulho através da barreira criada pelo curto cuspir ou costa de ferro com um calçadão sobre ele.
Palavras-chave: Condomínio
Absolutely love the location of this condo. Stayed in one of the other units two years ago but this is my second time at Villa Ocean Reef. The unit is spacious and comfortable. It is getting a little tired inside but who really hangs out inside on such a beautiful island? The drinking water and towels are plentiful and kitchen is pretty well stocked. Couches are comfortable if you needs to take a short siesta. Love Las Rocas right next door and being able to walk to the "busy" end of the beach then being able to return to the privacy of the of your own beach. West End is about a 40 minute walk and that is a neat little town as well. Snorkeling can be done straight out from the unit or across from Infinity Bay. Just watch for boats when crossing to the reef from the condo.
My complaints on this condo are minor but are the same complaints I had four years ago. First, the unit smells VERY musty and I wouldn't be surprised if there is some unseen mold going on in there. Second, the bushes are too high and you can not see the ocean without sitting on top of a very uncomfortable fixed structure wooden table (probably my biggest complaint). Third, the small bathroom can be very dark and a clear shower curtain would be helpful to let the light in. Not to mention, it is a challenge to get your entire body under the shower.
Walt Johnson has his name written on everything in that unit so i am assuming he is the owner. Hopefully, he reads the reviews. Bottom line: I would definitely stay here again but might check out one of the other units because of the smell and the view.
We,2 adult couples, recently traveled to Roatan for a 3 week vacation from winter and stayed in Ocean Reef Villa (2B). First of all, Roatan was a great vacation because we stayed on the beach in West Bay. Most anything we needed was within walking distance. Major grocery shopping must be done in Coxen Hole at Eldons or Plaza Mar There is a small store in the West Bay Mall that is like a deli which you can walk to. Also Woody's in West End which requires a water or land taxi.
Most of the activities are water based. These are our recommendations: To snorkel off the beach in front of the villa, go down the beach to the right and swim out along the buoy line and cross the boating path. You just need to stop and look for oncoming boats.
To snorkel off a boat go to West Bay Dive shop and inquire about open spaces on a dive boat. If not full of divers they will take you out for $5 a head. It gives you about 45 minutes of time in the water. Divers have priority at all times.
Parasailing, Kayaking, Zip line….been there done that.
Multiple restaurants for 3 meals a day.
Las Roccas (next door) for happy hour 3-6, and the sunset.
The villa has one thing going for it and that is location. Everything in West Bay is within walking distance
Overall the villa was OK but it is a tired place. It serves the need for a place to stay except you get the bonus of the location. Our stay started with water pressure problems. After a couple of days of investigation and work by John the plumbing problem was fixed and pressure was restored for the rest of out stay. The water does have an odor but it is not overbearing. Its well water. DirecTV service is offered. The problem is the reception because they are on the fringe of the reception area. Internet service is not provided. You can get a code from Las Rocas. $20 gets you 2 weeks or 2 gigs, whichever comes first. Reception and connection is spotty at best. This will not be a working vacation or gaming period for the kids. Email, text and news at best. There are plenty of towels. The kitchen is tired but fairly well stocked. The house is stocked well with TP, laundry soap, water and paper towels. The furniture is adequate but tired also. The plunge pool is clean except for the sand you bring in. Great place to lounge. House deck is nice also but there are no patio chairs. Just an uncomfortable nailed down picnic bench. The BBQ is atrocious. The house gets 3 stars and the location gets 5.
We spent a week in the condo and I highly recommend it to you. First of all, the price was extremely reasonable for the Christmas/New Year season. Linda was great to work with and responsive to all of our questions. Jensen picked us up at the airport and stopped while we bought groceries. We spent one full day with Jensen for an island tour and an unforgettable meal at La Sirena. My son finished his certification at Las Rocas and my husband and I did five dives each with this dive shop right next door. The location cannot be beat. The condo is spacious, but I wouldn't recommend that you try to fit 9 people in it. We were a party of six, and the two youngest children slept on the sofa bed in the living room. Some aspects of the condo and the building are weather worn, but everything was clean, cool, and comfortable. Every night we walked to a different restaurant on the main beach. The diving was world class. Alas, we did not win the war against the bugs. The mosquitos and sand flies extracted their pound of flesh. We appreciated the endless supply of water, and loads of towels.
If you are looking for North American luxury with room service and the works, you'll have to go elsewhere and spend three times as much. If you want to sleep right in the middle of the dance floor with DJ throbbing, head to Infinity Bay. However, if you want peace and quiet, unfettered views of the blue green sea from your private patio and your private beach, these villas will be home.
The condo is separated from West Bay proper by the rocking outcrop of Las Rocas dive resort. It has its own a stretch of private beach, with the reef a few hundred yards offshore providing decent snorkeling and calm waters. There's a bit more eel grass here than in the heavily trafficked West Bay, but the solitude was well worth it. Being apart from West Bay was a blessing. Just a few minutes walking brought us right to the action, but we could easily escape the parties and throngs of holiday revelers.
The unit we rented (Bayview 3b) was not super luxurious, but was perfectly comfortable and well appointed. We never once turned on the satellite TV, but it was an option. The kitchen had literally everything one might need (bakeware, fry pans, pots, blender, to-go mugs, coffee maker, lots of filtered potable water, etc). We self-catered nearly every meal, though many restaurants sit within easy walking distance.
Our unit was on the ground floor with 3 steps going down to the beach. We spent nearly all of our waking hours either in the sand and sea, or on the porch. The porch is semi-gated, has a handful of lounge chairs, along with a large glass table and 6 chairs for the table. The porch was very well shaded in the afternoons, and midday, when sun was strong, we simply moved the lounge chairs under the trees (just in front of the condo, in the sand) to get shade.
We highly recommend this condo to any and all travelers. It seemed especially nice for families (we brought our a 9-month old baby and his 75 year old grandma).
This condo was perfect for my family of four, spacious and comfortable. Everyone we worked with was fabulous. Linda took care of all of our arrangements, Jensen got us to and from the airport, Kevin checked in on us regularly and when we had a problem with one of the air conditioners had someone there to fix it within an hour.
The snorkeling just off shore was amazing. It is a little bit of a swim off shore, but the water is very shallow. My 10 year old managed it like a champ. We rented kayaks from Las Rocas for $10 for 4 hours. We also used Las Rocas to arrange zip lining at South Shore, they picked us up and then took us to West End when we were done. We walked to Gumbalimba Park (the tour is nice, don't waste your money on the zip line - go to South Shore). We enjoyed our quiet beach, but when we wanted to check out the excitement, the West Bay Beach was just around the corner. The small pool was perfect for cooling off, the kids loved it.
Thank you Linda for sharing this piece of Paradise with us. This place is located right on the beach with a private deck and a wonderful splash pool. (aka an unheated hot tub) The place is clean and spacious with 2 bathrooms. The outlets are all like we have in America. Bottled water was provided and everything was in working condition. There is a good restaurant called Las Rocas within 100 yds, food was good and Happy Hour starts at 3. Linda arranged for us to be picked up at the airport by Jensen. He drove us around, was always on time and made us feel comfortable. I would not recommend renting a car. His prices were always reasonable. The grounds crew was attentive and friendly.
Esta casa de férias está localizado em frente ao oceano (20 pés de borda da água) em uma área isolada de West Bay Beach devido a sua estrada de acesso privado. Eleita uma das 10 mais belas pela National Geographic, West Bay Beach é destinos mais ricos da Terra em Roatan. A baía é protegida ainda fica correntes frescas de ser no extremo ocidental da ilha. É a oeste de West End com um cume da montanha entre os dois. West End foi um destino de mergulho ocupado enquanto West Bay só era acessível através de barco. Praia de West Bay é bloqueado por resorts para o tráfego de veículos.
Outras atividades: compras, caiaque, canoagem, descasque, observação da vida selvagem, spa, mini-golfe
|Validade da Tarifa
|por noite
|Noite (fim de semana)
|por semana
|por mês *
|Pacote ou Evento
jan 30 2017 - fev 26 2017
Estadia mínima: 7 noite(s)
|Observações: As tarifas levam em consideração a estadia de 5 hóspedes, adicione R$ 31 por noite, por pessoa adicional
fev 27 2017 - abr 7 2017
Estadia mínima: 7 noite(s)
|Observações: As tarifas levam em consideração a estadia de 5 hóspedes, adicione R$ 31 por noite, por pessoa adicional
Easter / Semana Santa
abr 8 2017 - abr 17 2017
Estadia mínima: 7 noite(s)
|Observações: As tarifas levam em consideração a estadia de 5 hóspedes, adicione R$ 31 por noite, por pessoa adicional
Tarifa Básica
Estadia mínima: 3 noite(s)
A partir deR$ 650
|Observações: As tarifas levam em consideração a estadia de 2 hóspedes, adicione R$ 31 por noite, por pessoa adicional
|Cleaning fee < week
19% tax included in rate. Honduras requires Passports to be valid for 90 days past arrival (airlines recommend 6 months). Children's Passports are valid for 5 years and not 10 like adults. Full amount of security deposit will be forfeited for having more guests than booked without prior approval. No refund will be given for not meeting Visa requirements.
* Tarifa mensal aproximada. O valor real dependerá dos dias em que você de fato se hospedar no imóvel.


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Kate Upton Metallic Shoulder Bag
Kate Upton completed her ensemble with a silver Louis Vuitton Twist PM bag.
Kate Upton Blazer
Kate Upton enjoyed a date night wearing a double-breasted gray blazer and skinny jeans.
Kate Upton Pumps
Kate Upton chose a pair of pointy black pumps for her footwear.
Browse: Kate Upton | Metallic Shoulder Bag | Blazer | Pumps
Show Metallic Shoulder Bag Looks For:


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- Project Details
Title Organic Agriculture E-learning (FINESSA)
Project Number 2008-1-FI1-LEO05-00455
Product FINESSA Piloting Evaluation Report
Title FINESSA Piloting Evaluation Report
Product Type others
Marketing Text The report on the external evaluation of the piloting activities in the FINESSA project point to the strenghts and the areas needing further development in the parts of the FINESSA blended learning program that were tested by piloting.
Piloting was carried out in all of the target countries with a varying number of persons of whom most were learners in VET programs or apprenticeship programs and courses run by the association partners.
The report on the evaluation conducted by an external evaluator is based on interviews of learners and teachers.
It points to areas which were considered good by the participants as well high lights areas needing attention and further development.
Target group The primary target group were the project partners for whom the feedback is relevant in the use and further development of the project results. The report is available on the internet and will be useful for parties interested in using the FINESSA blended program or in developing it in future projects.
Result The findings of the evaluator have helped the project partners in making better use of the project results.
Area of application VET quality development
Homepage www.finessa.org
Product Languages English


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Speak Up, I Can't Hear You: Writing Voice – Kat Brzozowski
SCBWI Metro-NY Chapter
Tuesday, January 10, 2017 from 7:30 PM to 8:30 PM (EST)
Event Details
Speak Up, I Can't Hear You: Writing Voice – Kat Brzozowski
You've come up with a plot. You've created characters. You have a setting. Now how do you make your readers feel like these characters are really speaking to them? Voice is one of the most important elements of fiction and one of the hardest to master. We'll talk about how other authors craft voice successfully and how you can do it too. Be prepared to write!
Kat Brzozowski is an Editor at Swoon Reads/Feiwel & Friends, where she edits crowdsourced YA manuscripts from SwoonReads.com and acquires books traditionally through Feiwel & Friends. Previously, she was an Editor at Thomas Dunne Books, a division of St. Martin's Press. She has worked on a wide range of young adult fiction, from Anna-Marie McLemore's National Book Award longlister When the Moon Was Ours to new Fear Street books in R.L. Stine's best‐selling series, which has sold over eighty million copies worldwide. Kat is looking to acquire young adult fiction across a wide range of genres, especially contemporary, realistic YA with a strong hook; dark, contemporary fiction (not too issues-y), mysteries, suspense, and thrillers; and sci-fi and fantasy novels that are mostly rooted in this world. She is especially interested in YA with crossover appeal. When she's reading YA, she looks for a strong sense of voice, multi-dimensional characters, and realistic dialogue.
When & Where
Anthroposophical Society
138 West 15th Street
Ground floor, between 6th Avenue & 7th Avenue
New York,
Tuesday, January 10, 2017 from 7:30 PM to 8:30 PM (EST)
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As a little guy growing up with black and white television in Pittsburgh, I always thought the greatest thing on TV was professional wrestling. Today, as an old guy, I believe the greatest thing on TV is still professional wrestling. I know all the news that I get — like Archie Bunker — comes from…Read more
About: Peter Boyles
Recent Posts by Peter Boyles
Just when you thought the City and County of Denver….
... and State of Colorado could not do anything as stupid as the things they have done in the past . . . If you recall, when John Hickenlooper became the Mayor of Denver, he launched a program that he titled "The Ten Year Plan to End Homelessness." The Ten Year Plan plan not only…Read more
Brandon Marshall Stands Up, Brownstein Farber Takes A Knee
If you have been reading my award-winning columns in the The Glendale Daily Planet, I as Clark Kent, have had infinite fun pointing out the hypocrisy that reigns throughout the Mile High City. Denver, my personal Metropolis, has become laugh out loud for the mainstream media's inability to get a grasp on the obvious. I…Read more
Election 2016 —The Republican Party's Last Hoorah
It came to pass in those days, that the Republican Party has long doomed itself, and headed to the trash heap of history feeds up like the Phoenix bird out of its own ashes, emerges our hero, the modern Siegfried Republican stalwart Donald Trump. As I am writing this column in the middle of October…Read more
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This is your resource to discuss support topics with your peers, and learn from each other.
I recently purchased blackberry pearl and so far I've been really happy with a device except for one thing - I can't get it to sync with my PC! Every time I connect it to my computer, it cannot "see" the phone. The only indication that USB port is working is that the phone battery is charging. I really want to use my phone abilities to their fullest, please help! I installed a desktop software but it doesn't see the phone either (every time I click on Media manager icon, I get a message instructing me to connect the phone to computer)
Thank you!
If your query is resolved then please click on "Accept as Solution"
Click on the LIKE on the bottom right if the post deserves credit
If the above does not work, try the following:
1. Try plugging the USB into a different port on the computer.
2. Reboot your computer.
3. While the BB is plugged into the computer and the desktop manager is open, pull the battery out of the BB. Leave it out for 30 seconds. I know this seems odd but I have tried it with many of my clients and it's worked.
Also, sometimes using a docking station for a laptop causes problems.


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Lusaka, Zambia News
Local news for Lusaka, Zambia continually updated from thousands of sources on the web.
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Oct 19, 2016, 09.17 AM | Source: PTI
Hotels and restaurants can sell mineral water and aerated drinks above the maximum retail price unless it is sold over the counter, The Hotel and Restaurant Association of Western India said today.
Like this story, share it with millions of investors on M3
Hotels can sell water, soft drinks above MRP at tables: HRAWI
Hotels and restaurants can sell mineral water and aerated drinks above the maximum retail price unless it is sold over the counter, The Hotel and Restaurant Association of Western India said today.
"HRAWI, in a bid to remove any ambiguity over selling water, aerated drinks and similar commodities above the MRP, has issued a circular to its members clarifying that hotels and restaurants could continue to sell the same above the MRP," the Association said in a statement issued here.
"However, if such commodities are being sold over the counter then it is advised that they be sold at MRP only," it added.
The circular was issued in response to queries posed by members after media reports quoted Consumer Affairs Minister Ram Vilas Paswan saying that selling water and aerated drinks above MRP could attract fine and a jail term.
HRAWI is a member association in the western region of the Federation of Hotel and Restaurant Associations of India (FHRAI), the apex body of hotels and restaurants in the country.
"As per the present law, there is no such legal repercussion that can prosecute a hotel or restaurant for the sale of either packaged drinking water or aerated drinks or any such commodity above the MRP while being served in the premises i.e inside hotels and restaurants," FHRAI and HRAWI Chairman - Legal Matters sub-committee and HRAWI Secretary Pradeep Shetty said.
"So we have advised our members that they can continue selling at suitable rates as the MRP law applies to retailers only," Shetty added.
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40 000 Small Businesses in Bulgaria to Go Bankrupt by End-2012
Eleonora, Negulova, Chair of Bulgaria's National Association of Small and Medium Business (NASMB), has suggested that some 40 0000 registered SMEs, or 10% of the total, will go bankrupt by end-2012.
In a Thursday interview for the "Bulgaria On Air" TV station, Negulova claimed that managers were still failing to grasp the impact of the crisis and that it required a new approach.
She insisted that another major problem was intercompany indebtedness which had grown to BGN 100 B, according to recent data.
Negulova noted that the sectors experiencing serious difficulties were construction, the clothing industry, and the sectors which failed to implement technological upgrades.
Several days ago, the Bulgarian Construction Chamber (BCC) reported that some 27 000 small businesses had been closed and over 50 000 jobs lost in Q1, 2012.
According to data of the BCC, intercompany indebtedness amounted to BGN 104 B, while bad and restructured loans amounted to over 26% of the total of company loans by September 30 2012.
Meanwhile, a survey of Credit Insurance group Coface indicated that Bulgaria's bankruptcy rate was 0.12%.
However, Coface warned that the figures did not reflect the full picture in Bulgaria because the bankruptcy proceedings at Bulgarian courts were rather clumsy and the creditors often had no interest in starting them.
- » Ryanair Announces New Winter Services from Bulgaria
- » EVN Puts Gorna Arda Hydro Power Cascade on Hold
- » Bulgarian Resort Sunny Beach – the Cheapest Tourist Destination in the World
- » South Stream 'Could Be Revisited' after Bulgaria Election - Hungary FM
- » Regional Minister Popnikolov To Discuss Building Sanitation Programme With BDB, Municipalities
- » Deputy PM Yanev: Kostov Used His Influence To Appoint People
Unfortunately many of these bankruptcies are avoidable because they were businesses that should not have been started in the first place. I have observed so many small shops (in particular) that have started up either selling the wrong products, that is products that are not saleable for the local market where they are situated or the location for the products on sale is totally wrong. Classic examples I have observed is a shop in a nice mall but in a provincial town selling only high brand clothes such as Versace, D&G etc (not fakes but the real thing) or a shop selling high brand fitted kitchens in the same town, they both failed due to the prices being too high for the local market. Shops that open selling the same products (at the same prices) as established businesses almost next door, if you do thiss you must have something to lure away the customer from the established business, better prices or service. Bulgarians need to do a lot of market research and be business wise only that way will we see small businesses succeed instead of going bankrupt.


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Superpower synoptic, Edexcel June 2013
- Created by: Calum
- Created on: 06-06-13 14:15
First 443 words of the document:
The region in figure 1 has both economically and geo-politically one of the most strategically
important in the globe. This has occurred due to a whole range of factors including the
globalisation of world trade, the emergence of the counter colonial TNC's, the emergence of
NIC and BRIC economies and the legacy of a cold and world wars as well as imperialism for
most of the last century.
Each of the 4 countries named can be seen to demonstrate "super power mechanisms" both
hard and soft and two have a definite case to be termed superpowers within a multipolar
As figure 2 shows, the political systems in the region vary considerably in terms of
democracy and subsequently their interdependence and alliances with the rest of the globe.
The region is very significant to the global economy with 3 countries in terms of GDP
representing the second, third and fifteenth largest national economies.
2012 saw large political changes in the region. A new Chinese premier was selected, A
general election in Japan saw a swing to the right with new Prime minister Abe. In South
Korea an election saw the countries first female President and maybe a move away from the
hard line taken against North Korea by the previous govt. Finally the death of the North
Korean long standing dictator.....? saw the inheritance by his son and an uneasy future.
Political Disputes and territories
The island of Taiwan shows the complexity of politics in this region. Originally part of the
Dutch empire (Formosa) Taiwan became part of both the Chinese and Japanese empires as a
result of wars in the region. After world war 2 and Japanese defeat the island which is
ethnically/demographically Han Chinese was taken back from Japan . As Mao Zedong
defeated the Republic of China setting up the PRC, the ex Kuomintang government fled and
set up in Taiwan. Taiwan still remains officially the Republic of China and until 1992 had the
political objective of retaking mainland China. Most countries do not recognise the ROC as a
country and in many ways the island similar to Hong Kong is a self governing province of the
mainland. Recently there have been public calls in Taiwan to both officially become part of the
PRC and from others complete independence. The PRC military policy which is generally non
aggressive has stated that it would use military action if Taiwan was to claim full
Other pages in this set
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Taiwan is economically significant to China and is in it's own right the worlds
19th largest economies and home to large TNC's such as Foxcom.
In 2013 the Senkaku islands (Japanese name) became the centre of global attention
highlighting tensions between Japan and China . the 8 uninhabited privately owned islands
are only 7Km2 but do provide rights and access to reserves of petroleum, fishing grounds
and shipping lanes .…read more
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South Korea in particular are construed as
aggressive and threatening by China and North Korea.
The role of Japan in the war and its previous imperial colonial policies still leads to other
tensions in the area. Japan and South Korea both stake claim to Liancourt islands based on
medieval legislation!!. The Japanese government has refused to apologise for its previous
policies of "Comfort Women" where prostitution of Korean women was widespread.…read more
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American to Japanese industry. The Japanese economy then
went through 3 stages of growth initially focusing on heavy industry such as shipbuilding
followed by consumer goods and then High tech digital products. Japan invested heavily in
education. Small one room workshop style industries were encouraged to grow dramatically.
Japan was never in a position to rely on its raw materials and commodities of which it had
few.…read more
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Chinese TNC's do not feature high on global rankings but in terms of size and wealth,
companies like Sinopec appear in the top 10 according to the Fortune 500. Companies like
Lenovo, Foxconn and Huawei although not household names (which help create the cultural
hegemony some countries have) are in fact the world's largest players in the electronics and
telecommunications industry.…read more
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Growth Report
A criticism of all the economies either currently or historically has been the development of
research and development and technological innovation. The Growth report 2008 identified
key factors for growth including engagement with the global economy, specialising exports
and the transfer of key technologies. It also reported on the requirement to invest in
innovation and further education.…read more
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The size of the Chinese
market for food can have global implications, In 2013 another Chinese food safety scandal
surrounding infant milk formula led to the emptying of shelves in the UK as a huge import
black market was set up.
Traditional Chinese farms are fragmented or have insecure tenure meaning investment has
been limited. Less than half of Chinese farms have some form of mechanisation. State
investment into hybrid and GM crops is now very high.…read more
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In China the number of over 60's is set to double by 2030 (16% of total pop) to 365 million. A
2:1 dependency ratio by 2050 will create a huge burden on China as it faces a 4, 2, 1 syndrome
( a lack of comprehensive pension system means the burden of care falls on single
Grandchildren) as a result of the "famine solving" one child policy.…read more
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involvement in civil wars in both Sudan and Chad were due to securing oil supplies. China is
building ambitious pipelines westwards to Caucasus region. Fracking of natural gases may
also provide improved security but will impact on water security.
Japan has limited domestic energy supplies and is increasingly dependent on costly foreign
oil /gas imports(from middle east) especially since the closure of its extensive nuclear
programme after the tsunami disaster.…read more
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Twitter Outraged at Priyanka Chopra's Offensive Tee Shirt She Wore for a Magazine Cover
Priyanaka Chopra has gained much global recognition ever since she became a part of Hollywood, and good for her, too. Obviously, when one becomes an international celebrity, appearing on the cover of renowned magazines is not big deal. However, the fact that these celebrities are given enough importance to be placed on the cover for the world to see, means they hold enough power to influence the mindsets of the lot and also represent their point of view, on a global lever. It, therefore, becomes essential for these internationally recognised celebrities to take a thorough look at what they do before they convert their thoughts into actions.
This time around, Priyanka Chopra, played the wrong cards and ended up offending many. And with the advancement in social media, people made no efforts to keep their opinions to themselves and made sure she knew that she really hit the wrong nerve with the T-shirt she wore on cover photo on the Condé Nast Traveller Magazine.
Here is how Twitter reacted to her "insensitive" message on her Tee:
Oh, I'm sorry, I wasn't aware that being a refugee is a matter of choice…What were you thinking?! @CNTIndia @priyankachopra pic.twitter.com/WuyZv2iwp5
— Anum R. Chagani (@Anumero_1) October 8, 2016
Appalling, dehumanising, privilege-strutting, racist message on Priyanka Chopra's tee on this mag cover. @LakshmiGandhi have you seen this? pic.twitter.com/KbizRQ0LL1
— Sharanya Manivannan (@ranyamanivannan) October 8, 2016
@cntindia being a refugee is NOT a choice, it's a matter of survival. i was already disappointed for her comments abt feminism, now this -.-
— कमीनी (@1DerfulJelieber) October 8, 2016
@CNTIndia @priyankachopra offensive t-shirt. With 65 million ppl displaced, highest no. since WWII, to pretend as if it's a choice. #nonPC
— savita_pawnday (@savita_pawnday) October 9, 2016
@Ahmed7867864 @CNTIndia @priyankachopra I fixed it pic.twitter.com/tAOZUmcoIt
— Meena Kadri (@meanestindian) October 9, 2016
Oh, I'm sorry, I wasn't aware that being a refugee is a matter of choice…What were you thinking?! @CNTIndia @priyankachopra pic.twitter.com/WuyZv2iwp5
— Anum R. Chagani (@Anumero_1) October 8, 2016
Looks like Condé Nast Traveller India and Priyanka Chora have gotten themselves in a bit of a trouble here, is an apology on its way or are they just going to let this one pass?


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DEAR DR. ROACH: My sister broke out in a full-body rash of red, itchy blotches, and her doctor told her it was erythema multiforme. It is rare, and he sees only a few cases per year. Could you elaborate more on it -- causes, treatment, etc.? -- A.M.
DEAR DIDI: I have dogs that love to stick their noses or heads out of the car windows when they ride with me. Is that bad for them? They both are floppy eared dogs. -Concerned in Manteca, CA
Donald Trump's unorthodox campaign has performed a public service by shining the national spotlight on the problem of "sanctuary cities," which shelter illegal aliens from deportation. The tragedy of Kate Steinle, who died in the arms of her father after being shot by an illegal alien, is that her death was preventable, yet officials have defiantly defended their sanctuary policies.
With marijuana prohibition finally ending in states and cities across the land - including full legalization in Alaska, Colorado, Washington State, Oregon, and Washington, D.C. - who could be better than my friend Willie Nelson to lead the way for weed quality and social responsibility?
When South Carolina Gov. Nikki Haley signed a bill to boot the Confederate flag from State House grounds earlier this month, it was a beautiful moment - if decades late. State lawmakers finally acted out of revulsion from images of a confessed shooter posing with the Civil War relic before he shot to death nine African-American church parishioners June 17. Flag apologists lost their stomach for defending the banner as an emblem of states' rights.
Ninety-five percent of black voters in 2008 voted for then-Sen. Barack Obama. Surely a "progressive" black president would care about, empathize with and understand black America in a way no other president ever has or could, right? Exit polls from Pew Research show that 63 percent of all voters - and 65 percent of Obama voters - cited the economy as the number one reason they voted for him. Iraq was a distant second at 10 percent. Even for black Obama voters, "It's the economy, stupid."
Some of corporate America's biggest climate-change deniers - from Exxon-Mobil to the Koch Brothers - are dreading a potent storm that's gaining strength and headed right at them. It's the category-5 "Hurricane Francis," which threatens to overwhelm their flimsy ideological castles.
The American political class has failed the country, and should be fired. That is the clearest message from the summer surge of Bernie Sanders and the remarkable rise of Donald Trump.
The results of the first election of the 2016 presidential race are already in. It's the money primary, controlled not by voters, but by super-wealthy donors.
The results of the first election of the 2016 presidential race are already in. It's the money primary, controlled not by voters, but by super-wealthy donors.
The American political class has failed the country, and should be fired. That is the clearest message from the summer surge of Bernie Sanders and the remarkable rise of Donald Trump.
DEAR DR. ROACH: I'm a female, age 70, who is 5 feet, 4 inches tall and weighs 125 pounds. I have no problems with cholesterol, diabetes or blood pressure. I do not take any medications, just vitamins. I take dance exercise classes and walk often. I recently went for my checkup and found that I have a left bundle branch block. What happened? How did I get this? Is there anything I can do?
July 1 was one of those evenings when you feel blessed to be in San Francisco, especially if you are strolling along Pier 14. But every reader knows what happened next: A bullet struck Kathryn Steinle, 32, as she walked arm in arm with her father. Neither knew what had happened; the shot killed a vibrant woman - for which an immigrant with seven felony convictions and five deportations has been charged. (Juan Francisco Lopez-Sanchez has pleaded not guilty.) On Tuesday, less than a month later, Jim Steinle found himself where he never thought he would be - testifying before the Senate ...
DEAR DIDI: I have an 8 month old German Shepherd. She has so much energy! We read your column faithfully each week and value your opinion. My son likes to play laser light with Sassy and she is nuts for the game. You are training our neighbor's dog and he mentioned to us that you warned him against playing laser with dogs. He has a black lab. Is it a breed thing or all dogs that shouldn't play laser lights? - Manteca Dog Mommy
DEAR DR. ROACH: My husband's recent CT scan of his stomach and digestive system with and without contrast revealed that he has nodules on both adrenal glands. It was suggested that he undergo a blood test to determine if the nodules are producing hormones.
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Let's say you ask somebody a question. They give you an answer you don't like, so you pretend you didn't hear it ...
Still shell-shocked from his party's Nov. 8 beating, President Barack Obama said, "I'm confident that if I had run again and articulated it ...
For many women, getting a period for 3 to 8 days every month can be hellish - everything from bleeding, cramps, and fatigue to the humiliating ...
Did the community organizer from Harvard Law just deliver some personal payback to the IDF commando? So it would seem.
"Post-Truth." The Oxford English Dictionary named this its word of the year for 2016.
President-elect Donald Trump's transition continues to go smoothly. Actually, better than smoothly - confidently. More than confidently - transcendently.
Editor, Manteca Bulletin,
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It took me a second to realize why the Naks being drawn in the same group as La Tri wasn't a disaster - this is to avoid what happened to the Yaks in 2004, when Landon Donovan put more urine on the field than goals in the net, and Mexico went to Athens instead of the US. In theory, Canada could be the big roadblock, and wouldn't that be a great match. Realistically, it's up to either Costa Rica or Trinidad (and their trusty sidekick, Tobago). In their last one meetings with Mexico, the Naks are 0-0-1.
Besides, the US will undoubtedly have thousands of fans at the game, since it's right across the border in Juarez. I'm just glad that someone finally realized that, apart from a being a cultural landmark, Ciudad Juarez is one of the great soccer cities in the hemisphere, if not the world. I can't think of any more productive way to promote the game than to play as many matches in Juarez as humanly possible. In fact, let's put WPS teams in both El Paso AND Juarez, and have a derby!


text: Please forgive the length. A couple of weeks ago I started thinking about this phrase i hear from Christians on occasion. That phrase is "thou shall not put the Lord to the test". OK, were not supposed to put Him to the test, but what does that actually mean? What about Gideon and his famous fleece? So, I started with Jesus' words in Matthew/Mark when He was being tempted. I went back to the OT verse He quoted. Then I did a search on the Hebrew word used in that reference. Then I narrowed it down to those verses that dealt with people testing God. I also did a search of the NT for the Greek word used by Jesus in Matthew/Mark. What follows is the result of this study. Putting the Lord to the Test The Hebrew word for test in Exodus 17:2 is H5254. According to the Complete Word Study Dictionary Old Testament it means: nāsāh: A verb meaning to test, to try, to prove. Appearing nearly forty times in the Old Testament, this term often refers to God testing the faith and faithfulness of human beings, including Abraham (Gen_22:1); the nation of Israel (Exo_15:25; Exo_16:4; Exo_20:20; Deu_8:2, Deu_8:16; Deu_13:3 [4]; Jdg_2:22; Jdg_3:1, Jdg_3:4); Hezekiah (2Ch_32:31); David (Psa_26:2). Although people were forbidden from putting God to the test, they often did so (Exo_17:2, Exo_17:7; Num_14:22; Deu_6:16; Deu_33:8; Psa_78:18, Psa_78:41, Psa_78:56; Psa_95:9; Psa_106:14; Isa_7:12). Testing, however, does not always suggest tempting or enticing someone to sin, as when the Queen of Sheba tested Solomon's wisdom (1Ki_10:1; 2Ch_9:1); and Daniel's physical appearance was tested after a ten-day vegetarian diet (Dan_1:12, Dan_1:14). Finally, this term can refer to the testing of equipment, such as swords or armor (1Sa_17:39). It is found in the following verses: Gen_22:1; Exo_15:25; Exo_16:4; Exo_17:2; Exo_17:7; Exo_20:20; Num_14:22; Deu_4:34; Deu_6:16; Deu_8:2; Deu_8:16; Deu_13:3; Deu_28:56; Deu_33:8; Jdg_2:22; Jdg_3:1; Jdg_3:4; Jdg_6:39; 1Sa_17:39; 1Ki_10:1; 2Ch_9:1; 2Ch_32:31; Job_4:2; Psa_26:2; Psa_78:18; Psa_78:41; Psa_78:56; Psa_95:9; Psa_106:14; Ecc_2:1; Ecc_7:23; Isa_7:12; Dan_1:12; Dan_1:14 Below are the verses that deal with testing the Lord. (Exo 17:2) Therefore the people quarreled with Moses and said, "Give us water that we may drink." And Moses said to them, "Why do you quarrel with me? Why do you test the LORD?" (Exo 17:7) He named the place Massah and Meribah because of the quarrel of the sons of Israel, and because they tested the LORD, saying, "Is the LORD among us, or not?" In the passage from Exodus 17 the Israelites had been complaining. The event recorded here is when the people were complaining about not having water. Moses intercedes for them and God tells him to strike the rock at Horeb. What is implied here is a lack of faith. They complain instead of simply trusting God. In their complaints is the idea that God's plan to rescue them was not real and He was unable, or unwilling, to meet their needs. It is as if they are claiming that God failed to plan ahead. It also implies they doubt His faithfulness. (Num 14:22) "Surely all the men who have seen My glory and My signs which I performed in Egypt and in the wilderness, yet have put Me to the test these ten times and have not listened to My voice, At this point Caleb and Joshua have given a positive report after spying out the land of Canaan. The other spies had given a bad report. What was the difference? Caleb and Joshua included God, His power and faithfulness, in their report. The other focused on the giants. The people respond with complaining again. They grumble against Moses and Aaron. God is about to make them wander for 40 years to wait for the evil generation to die off. The evil generation has put God to the test time and time again by their complaints. They deny God's character as being faithful and able to give them what He has promised. God spares Caleb and Joshua for their faithfulness as they did not test Him. (Deu 6:16) "You shall not put the LORD your God to the test as you tested Him at Massah. This is a reference back to Exodus 17. It comes in the context of Moses' instructions to the Israelites. They were not to follow other gods but to fear God alone. (Jdg 6:39) Then Gideon said to God, "Do not let Your anger burn against me that I may speak once more; please let me make a test once more with the fleece, let it now be dry only on the fleece, and let there be dew on all the ground." This is a different situation. The Israelites have been disobedient and God has delivered them into the hands of the Midianites and Amalekites for seven years. Then the Angel of the Lord goes to Gideon. God is calling him to fight. Gideon is not complaining or doubting the character of God. Gideon wants to be sure it is God that is talking to him. So he prepares a sacrifice, which God consumes with fire. Gideon then goes, as commanded, and tears down the altar of Baal and the Asherah beside it. This angers the Midianites and they demand that Gideon be handed over to them. It doesn't happen. The Midianites and Amalekites assemble together. God sends an angel to assemblean army to follow him. Gideon wants know if God intends to deliver Israel through him. So he puts out his now famous fleece as a test. God responds positively. We then find verse 39. Gideon does not want to anger God. He does want to be sure he is hearing God, and hearing Him rightly. He puts out the fleece again. God, again, responds positively and Gideon goes out in obedience. This testing of God was not a complaint. It was not a denial of, or questioning of, God's character. It was a desire to be fully convinced that he was hearing from God. Gideon's heart here is one of obedience and desiring confirmation before action. It should be seen by us in a positive light. If he was complaining or disobedient that would be a different story. We should note that God does not get angry with him and he does not say Gideon did anything wrong here.


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text: We were spending the night in Parkersburg after a trip to Pa. and were looking for a place to have dinner. We love Italian but in our opinion this was one of the worse meals we have ever had. My husband always orders veal when it is on the menu. He ordered the veal scallopini and it was unlike any... More


text: BYZANTINE CHURCHES CHAP. and established the capital of a new kingdom at Tirnovo, while Constantinople itself had been captured by the forces of the Fourth Crusade and made the seat of a Latin kingdom. Consequently, it is not surprising to find that the Chora, like other churches of the ravaged city, was in a deplorable condition at the close of those calamitous days. Nothing seemed to have been done for the repair of the church immediately upon the recovery of the capital in 1261. The ruin which the Latin occupants of Constantinople left behind them was too great to be removed at once. The first reference to the Chora at this period occurs some fourteen years after the restoration of the Byzantine Empire, when the monastery, owing to its proximity to the palace of Blachernae, was assigned to the Patriarch Veccus as the house in which to lodge on the occasion of his audiences with Michael Palaeologus, on Tuesdays, to present petitions for the exercise of imperial generosity or justice. But the decay into which the establishment had fallen could not be long ignored, and a wealthy, talented, and influential citizen who resided in the neighbourhood, Theodore Metochites,1 decided to restore the edifice as a monument of the artistic revival of his own day. Theodore Metochites was one of the most remarkable men of his day. His tall, large, well-proportioned figure, his bright countenance, commanded attention wherever he appeared. He was, moreover, a great student of ancient Greek literature and of the literature of later times, and although never a master of style, became an author and attempted verse. He was much interested in astronomy, and one of his pupils, the historian Nicephorus Gregoras, recognised the true length of the year and proposed the reform of the calendar centuries before Pope Gregory. Theodore's memory was so retentive that he could converse on any topic with which he was familiar, as if reading from a book, and there was scarcely a subject on which he was not able to speak with the authority of an expert. He seemed a living library, *a walking encyclopaedia/ In fact, he belonged to the class of brilliant Greek scholars who 1 Niceph. Greg. I, p. 459.


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Prices could vary by region. I also highly suggesting printing out the Walmart coupon policy and keeping it handy.
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Paal Flaata Bless Us All (LP, Ltd. Blue Vinyl)
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Paal Flaata: Bless Us All (LP, Ltd. Blue Vinyl)(2014/Blue Mood) 10 tracks.
Paal Flaata, former singer of the country-rock band Midnight Choir, dedicated his latest album the songs of Mickey Newbury, the American singer-songwriter legend. The Norwegian singer with a warm baritone interprets Mickey Newbury songs on his own wonderful way with passion and respect. The album is produced by Göran Grini who accomanpies Paal Flaata on most of the songs. The tasteful arrangements remain discreetly in the background, but without losing its presence and give always enough space for the development of the beautiful and soft timbres of Paal Flaatas voice. An album full of enthusiasm and depth. Mickey Newbury would have been proud!
Songs Of Mickey Newburry
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Albumtitel: Bless Us All (LP, Ltd. Blue Vinyl)
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- Title Bless Us All (LP, Ltd. Blue Vinyl)
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Simple and sophisticated, the combination of lace and mesh, red material and gold hardware compliment each other to make the Seven 'til Midnight Red Cupids Bow Chemise & Thong a classic lingerie style.
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Quench your thirst at a hotel bar during your Chicago travels.
- Pull up a bar stool, and make friends with the locals
- Stay at an accommodation with the best cocktail mixers in town
- Drink up the best rates around
You've spent all day sightseeing around Chi-Town, and now you need a place to unwind.
The best hotel bars in Chicago are the perfect spots to regroup after exploring Buckingham Fountain at Grant Park and the marvelous shops along The Magnificent Mile. Downtown is buzzing with fabulous night life, where you can responsibly enjoy a cocktail before hitting the dance floor or order bottle service for a special occasion at Chicago hotel bars. Even if you're not a night owl drawn to the party scene, you can order a piping hot coffee for a caffeine boost or sip on non-alcoholic drinks.
When you're looking for some of the best hotel bars, Chicago has a vast selection. Here at Expedia, we'll provide you with a list of all the top hotels with lounges in the area boasting the amenities you desire. From wild clubs and trendy nightlife to live music and dive bars, let us help you find the watering hole perfect for your romp in Chicago. In addition to fabulous hotel bars, Chicago offers countless accommodations where you can get a good night's rest after painting the town red. Check out the downtown Chicago hotels for easy access to some of the most popular parties, restaurants, and attractions in the heart of The Windy City.


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Amid growing concern about pensions, David Robertson begins a series on who gets what by looking at civil servants
AS THE crisis in private sector pensions escalates, there is one group of workers who can still look forward to a comfortable retirement.
Civil servants have always grumbled that they are paid less than workers in the private sector, but as more and more companies cut their pension contributions, becoming a Whitehall pen-pusher has never looked so attractive.
There are 4.7 million people in public sector occupational pension schemes and they are beneficiaries of some of the most lucrative retirement benefits in Britain. They are nearly all in final-salary schemes, which pay out a pension based on pre-retirement salary. This


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yes, of course, his lordness is correct. the spadix is "hairy", with weird filaments coming out of it, not the spathe.
geoff, thanks for your email too. is your plant sagitattum? where did you obtain that? mine i'm told is a new undescribed species.
i'll have to go home now and smell my sumawongii again.
>A hairy SPATHE?????????? Or do you mean a hairy appendix or spadix??? The
>latter would be understandable. But a hairy spathe.......? Now THAT would be
>Lord Ulephallus
tsuh yang in nyc


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Hotfrog Philippines provides information regarding Icon Hotel in Paranaque Metro Manila. Icon Hotel is located at 1010 Macapagal Avenue, Paranaque Metro Manila 1703 and provides Travel services.
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Hotfrog NewZealand provides information regarding Kiwi A Salt. Kiwi A Salt provides Car services. Contact them on +64 7 884 8704 or by visiting them on their website http://www.kiwiasalt.co.nz.
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