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van der Heyde H.C.,La Jolla Infectious Disease Institute
Methods in molecular biology (Clifton, N.J.) | Year: 2011
The Enzyme-Linked Immunosorbent Assay (ELISA) and Western Blot analysis have been workhorse techniques for the analysis of protein levels and state, such as phosphorylation. The ELISA is also useful for measuring the affinity of a molecule for its ligand. The disadvantage of these techniques is that only a single protein can be analyzed for ELISA and a few (up to three) proteins for Western Blotting. Exact quantification is difficult with Western Blotting and changes are often reported as fold differences. We present here protocols for using fluorescent microspheres coated with the selected capture molecule to perform in essence several hundred mini ELISAs with each microsphere representing an ELISA; this reduces the variability of the assay. In addition, it is possible to analyze up to 100 analytes simultaneously using microspheres because each fluorescent microsphere exhibits distinct fluorescence in the red and far red channels: the fluorescence intensity in the channels in the red and far red channels (up to ten different intensities for each channel leading to a 10 × 10 matrix of intensities) constitutes the address for each analyte. Source
van der Heyde H.C.,La Jolla Infectious Disease Institute
Methods in molecular biology (Clifton, N.J.) | Year: 2011
Cell-derived microparticles (MPs) are increasingly recognized as important cell-to-cell signaling mechanisms and may exhibit important functions in homeostasis but also in pathogenesis. Indeed, MPs are associated with a number of diseases inhibiting their production that protects against pathogenesis. MPs are distinct from exosomes and apoptotic bodies, often exhibiting the membrane proteins of the activated or apoptotic cell from which they are derived. Electron microscopic analyses have shown that MPs are produced by all cell types tested to date, and ELISA-based assays have established that increased numbers of MPs are produced following cell activation. These approaches do not, however, determine the exact number of MPs and distribution of functional proteins on their surface. Flow cytometry represents an obvious approach to analyze MPs, and we present here a method to assess the number and phenotype of MPs by using a conventional flow cytometer. We also present the caveats with this method and describe a new imaging flow cytometry approach that overcomes these limitations. Source
Osteopontin mediates tumorigenic transformation of a preneoplastic murine cell line by suppressing anoikis: An Arg-Gly-Asp-dependent-focal adhesion kinase-caspase-8 axis
Hsieh Y.-H.,University of Alabama at Birmingham |
van der Heyde H.,La Jolla Infectious Disease Institute |
Oh E.-S.,Ewha Womans University |
Guan J.-L.,University of Michigan |
Chang P.-L.,University of Alabama at Birmingham
Molecular Carcinogenesis | Year: 2015
Osteopontin (OPN), an adhesive, matricellular glycoprotein, is a rate-limiting factor in tumor promotion of skin carcinogenesis. With a tumor promotion model, the JB6 Cl41.5a cell line, we have shown that suppressing 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced OPN expression markedly inhibits TPA-induced colony formation in soft agar, an assay indicative of tumorigenic transformation. Further, the addition of exogenous OPN promotes colony formation of these cells. These findings support a function of OPN in mediating TPA-induced neoplastic transformation of JB6 cells. In regard to the mechanism of action by OPN, we hypothesized that, for JB6 cells grown in soft-agar, secreted OPN induced by TPA stimulates cell proliferation and/or prevents anoikis to facilitate TPA-induced colony formation. Analyses of cell cycle and cyclin D1 expression, and direct cell counting of JB6 cells treated with OPN indicate that OPN does not stimulate cell proliferation relative to non-treated controls. Instead, at 24h, OPN decreases anoikis by 41%, as assessed by annexin V assays. Further, in suspended cells OPN suppresses caspase-8 activation, which is mediated specifically through its RGD-cell binding motif that transduces signals through integrin receptors. Transfection studies with wild-type and mutant focal adhesion kinases (FAK) and Western blot analyses suggest that OPN suppression of caspase-8 activation is mediated through phosphorylation of FAK at Tyr861. In summary, these studies indicate that induced OPN is a microenvironment modulator that facilitates tumorigenic transformation of JB6 cells by inhibiting anoikis through its RGD-dependent suppression of caspase-8 activity, which is mediated in part through the activation of FAK at Tyr861. © 2013 Wiley Periodicals, Inc. Source
Grau G.E.R.,University of Sydney |
Grau G.E.R.,La Jolla Infectious Disease Institute
Future Microbiology | Year: 2012
Cerebral malaria is one of a number of clinical syndromes associated with infection by human malaria parasites of the genus Plasmodium. The etiology of cerebral malaria derives from sequestration of parasitized red cells in brain microvasculature and is thought to be enhanced by the proinflammatory status of the host and virulence characteristics of the infecting parasite variant. In this article we examine the range of factors thought to influence the development of Plasmodium falciparum cerebral malaria in humans and review the evidence to support their role. © 2012 Future Medicine Ltd. Source
Host-derived osteopontin maintains an acute inflammatory response to suppress early progression of extrinsic cancer cells
Hsieh Y.-H.,University of Alabama at Birmingham |
Margaret Juliana M.,University of Alabama at Birmingham |
Ho K.-J.,University of Alabama at Birmingham |
Kuo H.-C.,University of Alabama at Birmingham |
And 3 more authors.
International Journal of Cancer | Year: 2012
The matricellular protein osteopontin (OPN), expressed in various cancer types and elevated in the blood of cancer patients, is thought to have different functions when derived from host versus cancer cells. To assess the effect of host-derived OPN on growth of cancers of epithelial origin, we established a line of cutaneous squamous cell carcinoma (SCC) cells, named ONSC, which lacks the OPN gene and develops SCC in syngeneic wild-type (WT) and OPN-null mice. At 8 and/or 10 week after subcutaneous injection of ONSC cells in mice, however, there was a lower tumor incidence in WT mice, suggesting that host-derived OPN is associated with suppression of early growth of extrinsic cancer cells. Histological, immunohistochemical, biochemical and hematological analyses were performed on the tumor microenvironment and blood from tumor-bearing mice during the first week after implantation. Host-derived OPN suppression of extrinsic ONSC cell progression is likely mediated through elicitation of an early innate inflammatory response, through its function as a chemoattractant and/or by enhancing survival of inflammatory cells. Further, consistent with a previous report, the serum levels of host-derived OPN, which are elevated during the early phase of tumor growth in mice implanted with ONSC, appear to reflect an anti-tumor progression effect. Copyright © 2011 UICC. Source


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The Captain's Challenge
Winning the Ryder Cup
By (author) Bruce Critchley
Format: Hardback
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Captain's Challenge by Bruce Critchley
Book DescriptionFor those old enough to remember, Ryder Cups prior to the 1980s were often dispiriting affairs. Our little island band of hopefuls took on the glamorous plutocrats of American golf every couple of years, and usually got soundly beaten for their impertinence.There was the occasional surprising exception. Dai Rees' 1957 team recovered from being 3-1 down after the foursomes at Lindrick to win five of the eight singles and halve another to record the only victory post-war. Then there was Tony Jacklin, our 1969 Open Champion, who inspired Great Britain and Ireland to an epic halved contest that same year. But that was just about that. Then in 1983, Jacklin got his hands on the tiller and turned it all around. Jack Nicklaus had proposed the inclusion of Europeans to try to even up the competition. For Jacklin that meant Seve Ballesteros.Together, with Seve on the course and Jacklin doing everything possible to raise the self-esteem, the standing and the prestige of the European players - and in the process convincing them that these matches genuinely were winnable - they took the fight to the Americans with astonishing results. "The Captain's Challenge" charts how Europe has won seven out of the last eleven contests and halved one other, and how, on just about every occasion, they have done so with teams statistically inferior to their opponents. The captain's role has been pivotal in blending twelve disparate individual talents into a highly competitive fighting force. In this book the various captains tell how they set about this demanding but fascinating task, often giving up months of their own time to ensure no stone was left unturned in pursuit of golf's ultimate team prize. Meaningful captaincy has often seemed a peculiarly British concept.Other sporting nations seem to get by just picking the appropriate number of their best players and electing the most senior to lead the way. For Europe in the Ryder Cup there has been much more to it and "The Captain's Challenge" is an in-depth look at just how the various holders of the post went about their task.
Buy Captain's Challenge book by Bruce Critchley from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9781848310261
(218mm x 144mm x 26mm)
Pages: 240
Imprint: Icon Books Ltd
Publisher: Icon Books Ltd
Publish Date: 4-Sep-2008
Country of Publication: United Kingdom
Books By Author Bruce Critchley
Ryder Cup, Paperback (September 2010)
2010 is Ryder Cup year. This golf match, contested biennially by Europe and the USA, takes place at Celtic Manor, Wales, in October. After a trio of resounding victories for Europe, the USA fought back hard in 2008 to seize the cup and re-establish their playing dominance. This title offers a chronicle of this event.
Creating Classics, Hardback (November 2008)» View all books by Bruce Critchley
Harry Shapland Colt is one of the greatest golf-course architects. Having designed or influenced the layout of many of the world's most famous golf courses - Muirfield, Pine Valley, Wentworth - Colt's creations provide an enduring, pulse-racing test for golfers. This title tells the story of this golf visionary.
» Have you read this book? We'd like to know what you think about it - write a review about Captain's Challenge book by Bruce Critchley and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a member - it's free to sign up!)
Author Biography - Bruce Critchley
Bruce Critchley played for Great Britain and Ireland against the USA in the Walker Cup and has commentated on top golf tournaments for the last 25 years, first on the BBC and recently as the leading golf commentator on Sky, for whom he will be covering the 2008 Ryder Cup. Colin Montgomerie has been Europe's undisputed leading golfer over the last 15 years, winning the Order of Merit an unprecedented seven consecutive times.
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subset: commoncrawl


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Every surface in the space it's covered by a different material that creates an uncompromised composition, that leads to an explosion of feelings and when you leave, the urge to come back again to this place.
Posts Tagged 'Cyprus'
Rokoko kitchen bar by M.O.B. Interior Architects, Nicosia – CyprusDecember 5th, 2016
Miele Hair Spa by Offset Design Studio, Nicosia – CyprusNovember 2nd, 2016
The 'Anama Concept branding by Kristina Apostolou MohianakisFebruary 25th, 2015
Pralina Confectionery 2 by Rkitekts, Nicosia – CyprusJanuary 27th, 2015
Como restaurant by Studio Gad, Limassol – CyprusNovember 21st, 2014
M.O.B studio office, Nicosia – CyprusSeptember 18th, 2013
It was really challenging for us to manage the creation of a new concept without distorting the existing energy of the space. My main concept was to create a multilevel plan using the pictures of a city as a basic model. Where ever you stand in the studio, you get the feeling that you are watching the city through a large window.


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Brain Drug North Wales Phenomenal Brand-New Brain Pill - Reduce Cerebral Age Alpha Zxt Brain Booster
Advanced Brand New Human Brain Pill - Experience Sharper Cerebral Clarity And Out Perform Other People Half Your Age. Trademarked Active Ingredients. You Will Become Cheery, Vitalized, Focussed And Pushing Your Cognitive Caps. Go For It. Alpha Zxt Brain Booster
Memory is what specifies our everyday existence. We remember concepts in the present with our short-term memory while we keep previous occasions and also discovered significances in our long-term memory. Exactly what's more, memory does not work flawlessly and also has the tendency to degeneration with age. As we get older, it may take longer to recover information stored in our memory. It is typical to fail to remember points from time to time and there are a number of pointers on ways to enhance mind power and also mind memory and to advertise a healthy mind as a whole.
Brain Foods to Boost Memory as well as Brain Power
Diet plays a significant role webpage in brain health and wellness and memory. The most effective foods aid to increase memory and also mind function by motivating great circulation of blood to the brain. In fact there are various researches that connect specific foods with better cognitive feature, alertness and also memory.
Memory is boosted by appropriate diet, variant in daily life and also to analyze what you do.
Friend Johan Karlsen (28) safeguarded the other day his doctoral thesis in psychology as well as currently boasts to be doctor of something as special as memory. - Our memory makes us the power to change that we are. We are entirely dependent on it at all to function, claims Karlsen. Short-term memory is among Karlsen's favorite subjects. It can bring most of us up in awkward scenarios if it stops working. Who has not neglected the name of an individual you simply satisfied?
Alpha Zxt Brain Booster Acton 01720
Also video game are promoted as great for memory. TELEVISION, nonetheless, could have a numbing result, since you just passively obtain, without assuming so much. Karlsen motivate individuals to break routines that define and also govern daily life.
Lots of people always adhere to well established procedures.
This program was made to assist you obtain a far better understanding of on your own and also that you were predestined to come to be. Brain Typing by Jonathan Niednagal inevitably aids the person that is looking for themselves quit wasting time as well as realize that it is they actually are. There are 16 different brain kinds, each one with different faults and unique skills. After learning exactly what classification read you come under, thousands of inquiries that occur within your mind concerning exactly what instructions to take, what job path to choose, etc. will be eliminated.
This program is the utmost "time-saver" of the century.
This program can potentially remove much of the complication as well as stress that includes parent. Not all parents are birthed with kids of the exact same brain type, which could regrettably create troubles later on later on. By recognizing, you'll have the ability to successfully handle your youngster's tantrum, understand what sort of after-school activities are best for them (if any kind of at all), recognize whether your youngster should be home-schooled, as well as how you can approach them when having essential talks.
When it pertains to close, individual partnerships, comprehending your partner is important.
There could even be a chance that you're with the incorrect person. However, if you're with somebody that is totally other from you, Brain Keying by Jonathan Niednagal discusses how you can get on and also make it function.
A great deal of the troubles individuals experience originated from the line of work they do. What takes place if you're in the wrong line of work? You end up being dissatisfied and inefficient in all locations of life. Your individual relationships experience since you are not where you are meant to be in life. Mind Keying by Jonathan Niednagal brings to light the kinds of jobs that will certainly function the most effective for you, giving you with the chance making an efficient modification.
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After spending some time to recognize yourself and also the people around you, the globe will certainly make far more sense compared to before. Why is it that you behave the manner in which you do? Having this question addressed will certainly place a lot of points into perspective. Finally, you can determine that you really are, what sorts of people you get along with the most effective, and also put an end to the search for self-understanding. Mind Inputting by Jonathan Niednagal will help you to conserve time and also proceed with the life you were indicated to live.
It's lastly time to obtain our brain back. This suggests a trip to the Forbidden Area and also a grand battle with Dr. Mobius' army. You could intend to finish up some service with the Think Tank though, which will enable a few calm alternatives for the closing of Old Globe Blues
When you have all 3 items of modern technology, you can make the huge press right into Dr. Mobius' lab.
This is the pursuit for Dr. Borous. When you speak with him, you can speak about his study and also possibly share rage for his creation of nightstalkers as well as cazadors. The vital conversation has to do with Gabe though. If you've been to X-8 as well as mosted likely to the observation deck, he ought to have a memory of turning Gabe right into a substantial cyberdog.
You ought to be able to talk about Gabe to Borous, as well as pick up the official quest.
If you click to investigate talk with Dr. 8, you will certainly just obtain fixed for a number of concerns. After you ask a couple of points though, you'll get the opportunity for an ability check. With 75 points in Science, or 7 points in Understanding, you can find out that he's speaking in repeating lines of code.
You could after that utilize the same 75 points in Science to threaten to hack him. Evil characters can then compel his conformity and make him hand over some ammunition, while excellent personalities could comfort him as well as state that they would certainly never ever do it.
After reassuring him a bit, you need to finish the mission.
This is a fairly easy one. You just should talk with Dr. Dala and examine her regarding her unusual interest in the human body. Then point, you have a few choices. Those with Girl Awesome or Cherchez La Femme can simply utilize that to obtain Dala to open up. There's also a choice for those with a good quantity in Speech, or evidently, you should have the ability to show her an actual teddy bear to stimulate some feelings in her. You could quickly obtain among these from her room in the Think Tank (simply rise a level and search in the secured rooms) or from her old residence in Higgs Town.
Regardless of just how you obtain her to be honest with you concerning her odd tourist attraction to your bio-rhythms, you could then accept let her 'examine" you. After an awkward minute, you'll obtain some energy cells and her warm thanks
As soon as you have your allies in the Brain trust, you could go out to discover Dr. Mobius.
It's a long walk through a dangerous valley. You'll most likely discover a variety of lobotomites or even some Y-17 harness fits. I presume that you fit battling these enemies by now however. The actual method will be exactly what takes place when you actually get to the door to the Forbidden Area.
There is an army of roboscorpions waiting at the door. When you come close to the door for the X-42 battle room, a lot of scorpions will certainly spawn in.
I highly suggest that you reach the edge of the battleground promptly. Fire as you relocate. You need to have the ability to use a proton axe or the antenna to keep them away. One swipe will disable them momentarily, that makes the battle far more convenient.
If you keep dropping back, you need to be able to just brush off the laser damage as well as slim them out. With a few stimpaks, you'll be great.
The last action, if you cannot hack an Extremely Hard computer, is to order a mint condition LAER off of the table in the shelter in the back best. Keep in mind that you ought to be able to jump over the rails to save yourself some pain.
Once it's dead, make certain that you look the remains. There's a final setup for the sonic emitter, 'roboscorpion," inside it. When that's done, obtain onto the raised bridge as well as go through the door to reach Dr. Mobius' lair.
Once you obtain your mind, you'll need to face Dr. Klein.
Travel back to the Think Tank, and also consider switching your body organs back into area at the Auto-Doc.
As the display alerts, talking with the Think Tank will force a finishing. Make sure that you have actually done every little thing that you want to do, although you can return as well as do the majority of the pursuits after the ending. You currently have a few alternatives to handle them.
If you did all of their missions, you could just inform Dr. Klein to 'consult his coworkers", that will certainly choose not to battle you. You can then make him give up and consent to remain in the Big Empty with no skill checks.


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This week's "Bruschi's Breakdown" has been posted on ESPNBoston.com, with former Patriots linebacker Tedy Bruschi providing his insight on the team's upcoming game against the Saints.
Of the team's second-half struggles in its three losses, Bruschi says:
"This is out of character for a Bill Belichick-coached team, but at this point of the season, you pretty much are what you are -- you've had all training camp, then September, October and November to develop your identity. And right now the Patriots aren't a second-half team. That can end up being a huge problem in terms of your season being over early. That being said, I think if the Patriots beat the Saints, they have a chance to eliminate that label and the reason why is this: If you solve a problem like that in a big game, against a great team, it can sometimes flip a switch and you can ride that through toward a successful season."


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|Show only Newton Stewart Hotels, Wigtown and the Rhins of Galloway
|Show only Kirkcudbright Hotels, Castle Douglas and New Galloway
|Show only Dumfries Hotels, Nithsdale and Thornhill
|Show only Moffat Hotels, Lockerbie and Langholm
The Old Station House is situated in what was the station yard at Bridge of Dee..The guest accomodation is in two beautifully prepared ensuite rooms. Both rooms have king sized beds, TV and tea and coffee facilities. Room 1 has a large wet room attached and room 2 has an ensuite shower and toilet..Although the station closed in 1947 and the last trains passed through in the early 1960 s there are still a number of original features of the old station.
A 17th century country house hotel situated 3.5 miles from Dumfries on the mostly undiscovered and scenic Solway Coast..The hotel.nestles neatly within the parkland forest of Mabie with its award winning paths and mountain bike trails ..A favorite destination for romantic breaks, family get together and the mid week traveler looking for great accommodation and sumptuous food, all at realistic prices that will satisfy those that discover this gem of a hotel.
Standing in a commanding position, high on the Galloway Cliffs, The Portpatrick Hotel is magical and the vistas are unspoilt offering some of the most spectacular views in Britain..As well as comfortable bedrooms with everything you would expect in a modern establishment, the Portpatrick Hotel also offers stunningly decorated public areas including a comfortable lounge and adjacent bar as well a spacious and elegant dining room.
The Bruce Hotel is a 20-bedroom, 3-star hotel, centrally located in Newton Stewart in the heart of the beautiful Dumfries and Galloway region in southwest Scotland..All bedrooms have en-suite facilities, with TV, radio, hair dryer, and tea & coffee making facilities. Offering excellent accommodation in a traditional Scottish style, the Bruce Hotel is renowned for its outstanding food, friendly service, welcoming atmosphere and good value. Galloway is very popular for its hill-walking, cycle touring, mountain biking, fishing, shooting, golfing & motor-cycling.
Welcome to the Ecclefechan Hotel in Dumfries and Galloway. A listed building which began life in the 1730 s and thus steeped in history. We are located seconds from junction 19 on the M74 providing easy access from anywhere in the UK. We have sixteen bedrooms and are undergoing a refurbishment programme, updating our rooms with en-suite facilities throughout and modernising our public and service areas. We are a family run business that prides itself on giving a warm welcome and making your stay a memorable one.
The Craighlaw Arms is a small but cosy family owned hotel where our informal comfortable environment provides the perfect escape destination..Situated in Kirkcowan, just seven miles from the town of Newton Stewart and perfectly situated for those planning to travel on the ferry to Ireland. We offer an idyllic retreat in the heart of the Galloway countryside. We cater for families and small groups of walkers, cyclists, golfers or shooters or simply those who would like to take things at a more leisurely pace.
.Only 45 minutes from Glasgow, over 1 hour from Edinburgh and 15 minutes.drive from historic Gretna, the Moffat House Hotel by Best Western is the ideal retreat to help you make the most of your time in the area. Set within private grounds, this stunning Victorian style hotel combines traditional elegance, comfort and a warm welcome. Keep connected from the comfort of your guest room with WiFi. Your room uniquely reflects the character of this traditional building without compromising on modern amenities.
.We at the Kenmuir Arms would like to welcome you to our friendly little hotel..The Kenmuir Arms Hotel is situated in the beautiful village of New Luce in the delightful Dumfries and Galloway region of southern Scotland...Accommodation at the Kenmuir Arms is provided by six comfortable rooms, a four bedded en suite (bath and shower)family room, a double en suite.and a twin en suite.The other three rooms, one family, one double and one twin, share a shower and bathroom on the same floor.
The Balmoral Hotel is a traditional Scottish coaching Inn located in the lovely small town of Moffat, Dumfriesshire. We offer great food and accommodation and if you are looking for a friendly welcome in a relaxed and informal setting then we are sure you will enjoy your stay with us in Moffat. Easy access to the motorway network - just 5 mins from junction 15 on the M74 (Beattock turn off)..The Balmoral Hotel is a small 16 bedroom hotel situated in Moffat, a lovely small town in Dumfriesshire.
The Queens Hotel Lockerbie.where a warm welcome, good food and beautiful accommodation awaits you..As a privately run country house hotel standing proudly in over three acres of its own lovingly tended grounds, the Queens offers a unique combination of character, convenience and quality..Its semi-rural location on the outskirts of Lockerbie.which is cradled in the beautiful southern edge of Dumfries and Galloway, is very easily accessible from the M74. Our location makes the Queens your perfect Half-way resting place and a superb gateway to the highlands.
Family run Motel and Restaurant situated on beautiful Scottish Loch. Ideal Location for travellelling to Ferry Ports for travel to Ireland. Motel is situated beside A75 truck road which runs from Carlisle to Cairnryan/Stranraer..Ideal for Famillies and for watersports enthusiastics , as only place in South West Scotland to accomodate Jet Skis and Speedboats..Ideal For Fishing..Restaurant/Bar on site .Family Room available and also two bedroom apartment.
Located within Welcome Break Service Area Gretna Green. Days Inn offers an ideally located base for exploring Gretna Green, Carlisle and the Solway Coast. Situated just over the border in Scotland and 16 miles from Carlisle Airport..All rooms are en-suite with both bath & shower. Remote control TV and complimentary hot drinks tray in each room. Free WiFi facilities when you book this hotel.
After a major renovation and restyle, the contemporary Birchtree Hotel is now open!.The perfect setting from a leisurely coffee to a night to remember with friends..Why not stayover in 1 of our 12 ensuite bedrooms and enjoy the local area after a fresh breakfast cooked to your liking...Designed to celebrate the local area, come join us for a chilled glass of your favourite in our famous bar..Family owned, we are passionate about hospitality and offer an exceptional quality of food and drink throughout.
Decorated with a blend of antique and more modern furnishings, centrally.heated throughout and in an excellent location for exploring this region of.Scotland and playing golf. You will be most welcome in the warmest of.hospitality traditions... We have welcomed an ever increasing number of golfers to The Imperial Hotel..With more than 34 golf courses in the area, great countryside and our.hospitality we are perfect for golf breaks, they have all enjoyed their stay.and many return year on year...We have a total of 12 bedrooms.
The new, exciting Smiths at Gretna Green embraces both tradition and modern day comfort with inspirational design set against a historical backdrop. Guests can enjoy a blend of professional, relaxed hospitality along with first class facilities..Smiths at Gretna Green is the most hip and contemporary hotel for miles with luxurious bedrooms that have been designed to offer guests not just a bedroom but a spacious living environment complete with modern facilities such as flatscreen TVs, DVD players and broadband internet access.
The Bladnoch Inn offers good food, accommodation and a place to relax and enjoy fine ales and our extensive range of spirits..We aim to make your stay at The Bladnoch as comfortable and enjoyable as possible. br /.br /.br /.br / We have four letting rooms, two of which are en-suite and all have a television, hairdryer and tea and coffee-making facilities. All our bedrooms are bright, fresh and comfortably furnished..Please let us know if you have any special requirements.
This delightful family-run hotel is nestled amidst the rolling South Scotland countryside, minutes from the M74 and near to Carlisle it offers great food, free parking and a thoroughly warm welcome..Located on the outskirts of romantic Gretna Green, the Mill Forge is a quaint complex of historic Grade-B listed buildings dating back to the 1700 s. A popular wedding venue, it is renowned for its tranquil surroundings and friendly service..Within the beautiful landscaped grounds and sited around three attractive courtyards are 33 comfortable en-suite guestrooms.
The Cairndale Hotel and Leisure Club is ideally situated close to Dumfries town centre.and next door to the new DGone Leisure Complex..The hotel boasts a total of 91 letting bedrooms with the majority of rooms having bath and shower..A limited number of ground floor rooms are available.as well as a number of rooms with walk in showers..Recent upgrading has seen the refurbishment of 30 bedrooms in the hotel where the feel is.modern and contemporary. Free Wifi is available throughout the hotel.
The Corner House Hotel is a well-established, family-run hotel situated in the centre of the small Scottish town of Annan. The hotel is a traditional sandstone building with all the modern amenities our guests would require. br /.br /.br /.br / Located just off the M74, our location is ideal for visitors to Dumfries and Galloway, the Central Belt (Glasgow and Edinburgh), Gretna Green and beautiful Solway Coast. We are a popular destination for a number of outdoor activities such as cycling, fishing, walking and golfing.
Live like a Scottish Laird for a few days.Kirroughtree House Hotel is a country Mansion set within its own gardens, a golf course close by, only minutes from the country town of Newton Stewart which is set on the banks of the River Cree.
Offering Free Wi-Fi and ample free onsite parking, The Gables Hotel is conveniently situated only a mile from the M(A)74, M6 & A75 giving easy access to Glasgow, Dumfries & Carlisle...The Gables is an independent, family owned hotel in the heart of Gretna. The magnificent location, the traditional family feel and the friendly staff has established The Gables as one of the finest hotels in the area.
The Queeensberry Hotel And Restaurant Ltd,.Representing a £1. 4m investment, The Queensberry opened as a 15 bedroom hotel in July 2007. As a listed building on English Street, Dumfries that has been left unused for a number of years, The Barracuda Pub Group were keen to bring the building back into public use and preserve the hotels listed building consent. In recent years the Queensberry has been taken over by a private owner, the business is independently owned and is currently in the planning stages of a new refurbishment.
The Eskdale Hotel is an 18th Century Coaching Inn and stands prominently in the Marketplace of Langholm, the famous.Muckle Toon.of the Scottish Borders. The Hotel is family run and all guests are given a warm and friendly welcome. br /.br /.br /.br / Our Hotel consists of 14 bedrooms, 2 bars, a dining room and 2 function/meeting rooms which hold up to 120 persons. We are also the only hotel in the town to have our own private secure car park and a locked garage for bikes.
Situated on the High Street of Annan town centre, Queensberry Arms Hotel features free on-site parking and is within a minute s walk of local amenities such as shops and bars..An en suite bathroom is provided in each room at the Queensberry Arms, as well as a TV with Freeview channels and tea/coffee making facilities..A wide variety of main courses are served in the on-site restaurant, such as roast meats and steak and Guinness pie.
The proprietors personally supervise the smooth running of the hotel (a modernised listed building) which is situated in the heart of Gretna and is also the nearest hotel to the world famous Gretna Registration Office. Anvil Hall, Gretna Hall Blacksmiths and the Old Blacksmiths Shop are all within a five minutes drive from us.. Weddings and private functions can be catered for in one of our two function rooms, seating up to 50 guests.
The Nithsdale Hotel is situated in the Royal Burgh Town of Sanquhar, in the tranquil surroundings of the Nith Valley. We like to make all our guests very welcome with our warm, lively atmosphere..The Hotel is an ideal place to stay if you are doing the Southern Upland Way Walk, Lands End to John O Groats Cycle Run or Fishing on The River Nith.
The Crown Hotel is a first-class tavern in Lockerbie town centre and is one of the best venues in the south-west of Scotland. The Crown Hotel is situated in the centre of Lockerbie, just a few minutes walk from the town s railway station. The relatively close proximity and being one of the first Scottish towns for those travelling north has made Lockerbie an attractive and convenient.break.as well as being an important market and provincial town for this part of the south-west of Scotland.
The Manor Hotel & Restaurant is conveniently situated just two miles off the A75 (Gretna to Stranraer trunk road) Dumfries by-pass on the A709, some 8 miles to Lockerbie and the main North/South M74 Motorway. The hotel boasts not only comfortable en-suite bedrooms to suit most requirements, including a sleep five Family Room, but also a wide choice of either Bar or Restaurant food as well as a Childrens menu all at affordable prices. Food is available every night as well as Sunday lunchtimes. There is also a friendly village bar.
The Huntingdon is an entirely non smoking hotel. br /.br /.br /.br / Business travellers.A free, reliable and fast Wi-Fi internet connection is available..Work space in all the rooms..A large safe car park and a quiet lounge bar to relax in at the end of a long day. br /.br /.br /.br / Tourists.Four Castles, Abbeys, Museums, Rabbie Burns,.Robert the Bruce, J M Barrie, Thomas Carlyle, Commodore John Paul Jones, Many Lochs and rivers, The Solway coast, The Galloway Forrest.
Set amidst acres of stunning gardens, just 30 minutes from Gretna and 20 minutes from Dumfries.this Medieval Castle offers luxury accommodation, award winning dining, free Wi-Fi and a scenic location. Approached by a picturesque, tree-lined drive.the 15th Century Castle and a Baronial mansion perfectly blends the splendour of its historic past with exceptional service and modern amenities..Steeped in Scottish history, the castle s halls are adorned with medieval weapons, suites of armour, tapestries and banners, whilst offering the very best in modern luxury.
Welcome to the White Hart a great wee family run venue offering a lively pub atmosphere and first class accommodation. We are located in a quiet street close to Dumfries town centre. We ve got great beers on tap, the best internet jukebox, anywhere, karaoke, band nights and much more. There s free Wi-Fi throughout the building, which is a 170 years old. br /.br /.br /.br / The White Hart Hotel has been completely updated and refurbished with all 7 bedrooms finished to a very high standard.
A warm welcome awaits you at the family run Hazeldene Hotel.whether you are here for a wedding, business trip or overnight stay or just a meal in our restaurant or a few drinks in our bar. br /.br /.br /.br / The Hazeldene Hotel has a friendly home from home feel which you re sure to enjoy and our excellent restaurant serves good quality homemade dishes which are sure to whet your appetite.
Are you looking for a traditional Scottish, homely hotel, oozing a warmth and friendly welcome that will make you glad you ventured to this picturesque, corner of Dumfriesshire.Views over the estuary,.panoramic landscapes of the hills, stunning sunrise and sunset vistas, await you from your room...Getting out to explore on foot or car will get you up close with nature and offer scenic journeys that will give you lasting memories of your break in this lovely corner of Scotland.
Craigadam is quite special and offers something a bit different. Fine country house accommodation in a beautiful and convenient location..Guests and non residents are welcome to book for dinner which is taken family style.around the large oak table in the wood panelled dinning room. Much of the food comes from their own farm or within a few miles of it and the cooking is superb...Spacious and characterful accommodation in large courtyard rooms..Free wifi.....
Set in a 45 acre estate including woodland, The Friars Carse Country House Hotel is located only 7 miles from Dumfries town centre, yet.enjoys a tranquil rural location. Situated on the banks of the River Nith, the hotel boasts stunning views of the Dumfries & Galloway Countryside and the hotel s Private Salmon & Sea Trout River. All 21 en suite bedrooms have tea/coffee making facilities and TV, some with Free WiFi Internet access..The hotel s recently refurbished Holiday Cottage Accommodation is also available, situated within the hotel grounds.
A quiet family run hotel in the south-rhins area of Scotland..Ideal for the ferry to Ireland..The hotel has a licenced bar and restaurant specialising in good Scottish food..Nearby are six major gardens all open to the public,including Logan Botnical and Glenwhan..If you like your golf then we have four golf courses all within 15 minutes of the hotel with a further two in 30 minutes.
Behind the imposing Georgian columns of the Annandale Arms, you will find a small, smart, privately owned hotel..The bedrooms have recently undergone a major refurbishment..Decorated in a modern chic mode, all the rooms have pocket sprung luxury beds, en-suite bath or shower rooms, most have both. There are flat screne TVs as well as the usual tea coffee making facilities..The restaurant has a reputation for serving the best quality Scottish produce in an contemporary, uncompromising style.
Located in the picturesque town of Thornhill, this hotel offers comfort and style with a relaxed atmosphere, free Wi-Fi, free parking and an excellent onsite restaurant. Situated three miles from Drumlanrig Castle in Dumfries and Galloway and only 90 minutes from Edinburgh or Glasgow, the hotel is ideally located to explore some of Scotland s finest attractions and natural scenery..All ten bedrooms have been lovingly restored to the highest of standards, each with its own personality and charm.
Welcome to.The Ship , a family owned hotel business offering 4.luxury accommodation across ten en-suite bedrooms all recently renovated with designer bathrooms, flat screen TVs and coffee machines/fridge. Located in Gatehouse of Fleet a tranquil conservation village in the heart of Galloway - close to the Dark Skies Forest Park and less than a mile from world renowned sandy beaches.


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Lipitor, Atorvastatin News
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80-Year-Old Florida Man Is Catfished by Prostitute, Gets Mugged
Photo by seedfeeder via Wikipedia Commons
An 80-year-old man from Century Village in Deerfield Beach expecting to hook up with a female prostitute he met online instead was met by a man and then got robbed.
According to Boca Raton Police, the man had met a hooker named "Amy" on the internet. The two made plans to get together at the Quality Inn at 2899 N. Federal Highway on Sunday afternoon.
When the man arrived at the hotel, he saw "Amy" dressed in a leopard-print leotard. The man told police that once the two got inside "Amy's" room, something didn't feel right.
Maybe because "Amy" was actually a dude named "Frank."
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The victim stepped out of the hotel room, but as surveillance video shows, once he was outside, another man came up from behind him and stole his wallet and cell phone from his back pocket, according to police.
The man then called police and waited for them in the hotel lobby.
As he was waiting, he spotted the suspect walking through the lobby and then leave the hotel.
Boca Raton Police detectives investigating the crime made contact with "Amy," according to the report, and discovered that his actual name is Frank. According to the report, Frank told officers he knows the mugger only as "Chief."
Boca Raton Police released footage of the video that shows the victim getting robbed outside of Amy/Frank's hotel room. Chief Dan Alexander shared the video on his Facebook page with a description of the crime.
"There are certainly better (and safer) ways to find companionship," Chief Alexander writes in the description of the video. "Let's be careful out there."
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Vintage Jewels / Antique Haven,LLC ®
Vintage Jewels / Antique Haven / Deb Hancock, Glendale, AZ
Vintage Sterling Silver with 27 Mini Religious Medals Blue Enamel Charm Bracelet
$295.00 This linked marked sterling silver vintage bracelet is adorned with 27 medals securely attached. 25 of them are highly sought after and collectible blue enamel and one pink one. They are small and of various shapes and sizes... many of them are from France, some from Italy.These come from my personal collection,.. some from my Catholic school years in the 1950's and others I have accumulated while scouring antique stores in the U.S. The bracelet is 8-1/2" long but can be fastened anywhere on it for the perfect length. The largest charm is the ring. The clasp is a very secure spring ring style. Excellent condition.
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Relaxed Dentistry
Dentist, Pediatric Dentist, tooth decay
Before development of dental implants, dentures were the only alternative to replacing a missing tooth or teeth.
Implants are synthetic structures that are placed in the area of the tooth normally occupied by the root. Implants are anchored to the jawbone or metal framework on the bone and act as a foundation for an artificial tooth or permanent bridge. In some cases, implants can be used to attach dentures.
Not everyone is a candidate for a dental implant, however. For a successful implant to take hold, a candidate must have proper bone density and have a strong immune system. In all cases, dental implants require strict oral hygiene.
Implants are so well designed that they mimic the look and feel of natural teeth. Implants are usually made of a synthetic yet biocompatible material like metal or ceramic.
Surgery is necessary to prepare the area for an implant and place the implant in the mouth. Following the procedure, a period of time is required for the implant to take hold and for bone tissue to build up and anchor the device. In some cases, metal posts are inserted into the implant during a follow-up procedure to connect the tooth.
Because implants require surgery, patients are administered anesthesia and, if necessary, antibiotics to stave off infection following the procedure.
Like any restoration, implants require diligent oral hygiene and proper care to ensure they last a long time.
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Crowns are synthetic caps, usually made of a material like porcelain, placed on the top of a tooth. Crowns are
Teeth that are badly stained, shaped or crooked may be improved by a veneer placed on the surface of the
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Estate and letting agents in UK
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Established in 1992 we have grown to include a new homes division and a lettings division, all ... more


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HeavyMMA's Megan Olivi catches up with UFC heavyweight champion Junior dos Santos after his Wednesday workout session for UFC 146 in Las Vegas. watch video >>
ProMMAnow.com (www.prommanow.com) talks with Frank Mir before his title fight with Junior Dos Santos at UFC 146. watch video >>
Following UFC 146, Junior dos Santos and Frank Mir share the stage to talk about their title bout. Subscribe to our channel for more MMA videos! Click here: http://www.youtube.com/user/MMAFightingon watch video >>
UFC 146 weigh-in video highlights feature UFC champion Junior dos Santos, Frank Mir and the rest of the UFC 146 fight card stepping on the scale Friday at the MGM Grand in Las Vegas. "Subscribe to ou watch video >>
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Heavyweight champ Junior Dos Santos braces to defend his title against former beltholder Frank Mir in the main event of the unprecedented all-heavyweight event May 26. watch video >>
MMA H.E.A.T.'s Karyn Bryant talks with UFC Heavyweight Champ Junior Dos Santos at the UFC 146 open workouts, and hears what he has to say about fighting Frank Mir in his first title defense. JDS talk watch video >>
Watch heavyweight champion Junior dos Santos defend his title against former champion Frank Mir at UFC® 146: Dos Santos vs. Mir, live on Pay-Per-View, Saturday May 26 at 10PM/7PM, live from the MGM G watch video >>
Frank Mir has replaced Alistair Overeem as the challenger for the heavyweight title. This is an exclusive moment where Junior Dos Santos learns of his new opponent and gives his initial reaction to t watch video >>
UFC 146, MGM GRAND, Heavyweight champion Junior Dos Santos defends his title against former champ Frank Mir. By jhazizi21, LIKE and SUBSCRIBE. watch video >>


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Kevin Rudolf
B.A.M.F. Entertainment
Kevin Rudolf - That Other Ship
By DJ Z | one year ago
Editors Pick
Kevin Rudolf - Here's to Us
By richard | 3 years ago
Kevin Rudolf ft. Fred Durst, Lil Wayne & Birdman - Champions
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Kevin Rudolf - Don't Give Up
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Brisco ft. Kevin Rudolf - Stay Here Tonight
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Kevin Rudolf ft. Flo Rida - You Make the Rain Fall
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Kevin Rudolf Jumps "In the Mix" [DJBooth Interview Exclusive]
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Psychologists say that we're naturally wired to be attracted to people with multiple skills. With that, it can be assumed that singer, producer,...
Kevin Rudolf ft. Kid CuDi - Welcome to the World
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Controlling is the process management goes through to ensure plans are being implemented appropriately by evaluating performance and taking corrective action. This process involves looking at what was expected or intended to happen and then what actually has occurred.
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Oshawa Creek Trail is a 2.6 mile out and back trail located near Oshawa, Ontario, Canada that features a river. The trail is good for all skill levels and primarily used for hiking, walking, and trail running.
kid friendly
trail running
walking2 years ago
Nice walk or bike ride to Lake Ontario. You can go to Lakeview Park or Pumphouse Marsh Wildlife Reserve at the south end of the trail or the Oshawa Botanical Gardens at the north end.


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2 million Mass. voters expected to cast ballots on Election Day
Millions of people are expected to vote on Election Day. 22News explains what you can expect if you have yet to cast your ballot.
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Millions of people are expected to vote on Election Day. 22News explains what you can expect if you have yet to cast your ballot.
By the end of Election Day Secretary of State William Galvin expects that more than 3 million Massachusetts voters will have cast ballots.
With no statewide races on the ballot, much of the campaign conversation in the state has centered on the four ballot questions.
Veterans in western Massachusetts face a unique set of challenges when it comes to services.
Revenue collections last month eclipsed the state's newly revised estimates by $79 million.
Goldberg filed a bill that would direct UMass to work with the Dept. of Higher Education to develop the pilot on one of its campuses.
At least 16 cities and towns in western Massachusetts will end early voting on Thursday at 4 p.m.
22News explains how charter schools are performing in the urban communities of Massachusetts.
Springfield. Holyoke, Pittsfield, South Hadley, and Palmer will all consider whether to adopt the Community Preservation Act (CPA).
Police escorted protesters in wheelchairs out of the building after a group advocating for disability rights blocked its main entrance.
House Majority Leader Ronald Mariano, a Quincy Democrat who serves on the commission as an appointee of Speaker Robert DeLeo, said some of t…
The Republican has been attending events for his party's legislative candidates, and showing his support for Ballot Question 2.
22News explains why one state lawmaker is warning people about the safety issues with drowsy driving.
So far, it's been a pretty smooth transition. Crews are working 24/7 to tear down each of the 23 toll plazas along the Mass Pike.
About 83% of those who have driven on the Pike in the last few days already have an E-ZPass transponder.
Boston's Mayor and several US Senate candidates said would return more than $200,000 in campaign contributions linked to Thornton Law Firm.
Former Massachusetts House Speaker should be released early from prison because he can't eat or drink without a risk of choking.
Governor Charlie Baker's energy team has been putting together a new solar incentive proposal over the last six months.
Electronic tolling gantries had successfully processed nearly 3,000,000 transactions by 8:00 Monday morning.
A special State House commission met for the first time on Monday to explore how the state can oversee the online gaming industry.


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L'Autre Chose in Milan
L'Autre Chose opens its first boutique in the heart of Brera
L'Autre Chose opened its first boutique during Milan Fashion Week after the shops in Rome, Bologne, Milano Marittima and Cortina d'Ampezzo.
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Vittoria Mentasti's Dead Sea takes us to a place where the sky and the sea are one
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A chat with Kristin Prim, the founder of The Provocateur, the site that publishes letters written expressely by leading women addressing the whole female world. Vogue.it presents you an exclusive preview of the letter written by Dresden Dolls' Amanda Palmer
Fashion shows are changing: Burberry and all that's new on the runways
Menswear and womenswear collections will walk together and will be on sale right after the show. These are the news from Burberry but the evolution is generalized: runway shows are changing


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T's Restaurant
Located in the trendy Jiyugaoka district, this vegan restaurant serves a fusion of Japanese & western vegan cuisines, from its signature ramen dishes to pizza and risotto. Menu shows photos of the dishes. Also sells a range of vegan products. Apr 2016 updated menu no longer using honey. Open Mon-Sun 11:00am-10:00pm.
Category: Vegan, Pizza, Japanese, Western, Fusion
Reviews (17)First Review by Wozza
Really nice - Edit
The pasta is great. The strawberry ice cream is incredible!! I already missed it!
Pros: easy to find, reasonable price, delicious, cozy at
Cons: few selections for lunch
wow - Edit
Uno dei pochi ristoranti vegani in tokyo consigliato ottimo cibo staff e proprietaria gentilissimi
One of the few vegan restaurants in Tokyo recommended food great staff and owner very kind
a good place to go to - Edit
It is difficult to find vegan food in Tokyo so, T's restaurant is a welcome venue when you just want to order without having to explain your dietary requirements. The food , whilst not 'wow', it certainly is edible and will fill you up. The desserts are fairly good too. The staff are friendly and attentive.
Updated from previous review on 2016-08-01
Pros: soy meat dishes, thai curry, berry ice-cream
lovely atmosphere - Edit
Very nice restaurant with lovely staff and a comprehensive menu. Desserts are incredible!
1 Response
Alinyan 31 Jul 2016 - So why 4 starts and not 5?
delicious dinner, great atmosphere - Edit
A bit pricey, but worth every penny. The karaage and lasagna were amazing! And they sell vegan cup ramen and scones too
Pros: Lots of dishes, Cup ramen!, Close to the station
Cons: Pricey
Nice vegan event - Edit
I heard that Tantan noodle here was awesome. ここのタンタンメンはおいしかったと3人に言われた翌週、ヴィーガンのランチイベントがあったので参加。Next week I found a vegan lunch meetup and joined it. さらりと食べやすく、ユーリンチンも追加。Taste nice and I added vege Yu Lin Chi. ドリンクとサラダ付きのランチセットはお得。Reasonable lunch set with a drink and salad. フレキシタリアンによるヴィーガンイベントをここでやってみたいなと。It's going to be fun to have an event for flexitarian here. おいしかったです。ごちそうさまでした。
Pros: good value
Cons: well...
Fantastic place - Edit
We loved this place so much we went back 3 times. The ramen in here is the best I have ever tried! The price is very reasonable too. It's not hard to find once you find Keiyo street, but you need to be inside the station and have purchased a ticket.
Pros: Great food, Cheap price, Many choices
Cons: You need to have purchased a train ticke
1 Response
VeganMegane 28 Jul 2016 - I think you went to T's tan tan in Tokyo Station and not T's restaurant in Jiyugaoka. Same chain, different store. Here's the listing for T's tan tan: https://www.happycow.net/reviews/ts-tantan-tokyo-29533
A charming vegan restaurant in Jiyugaoka - Edit
Although slightly off the beaten path for tourists, this restaurant is a must visit for vegans and veggies in Tokyo!! The sister restaurant of T's TanTan ramen shop in Tokyo station, this charming bistro in the student neighborhood of Jiyugaoka (located in on the basement floor of a small shopping building) serves their famous ramen and much much more. Try their rich and creamy 'Doria' baked risotto dish - a classic 'Japanese-western' menu item, and their phenomenal parfait! 3-5min walk from Jiyugaoka station.
Pros: Varied menu , Lovely ambiance , English menu
Cons: out of the way from major tourist areas , Portions a bit small
amazing place - Edit
beautiful place, the staff are hospitable,
variety of delicious and beautiful dishes. without a doubt one of the best places I've been in.
T for tasty...? - Edit
Probably my favourite restaurant in Tokyo so far. There is so much variety on the menu and everything I've tried so far has been delicious. Everyone I've brought here (none of them veggie or vegan) has loved it too.
There are dishes from different countries including Italy, Thailand, China and Japan, so a wide range of tastes can be catered to. The desserts are delicious too and there's always at least one type of cake you cake take away as well as packaged biscuits, scones etc. They also sell a small variety of vegan foods you can cook at home, including a few of their own-made sauces/stocks. The white sauce in particular is something I haven't found elsewhere in Tokyo.
The waiters are all lovely and the owner herself sometimes wanders around and likes to have a chat. There is an English menu and all the staff seem to speak English to varying degrees, so there shouldn't be any problems for people who don't speak Japanese.
The restaurant is in the basement of Luz department store and is a short walk from Jiyugaoka station.
Updated from previous review on Wednesday April 01, 2015
Pros: Great variety, Friendly service
Delightful! - Edit
My Japanese hosts (who are not vegan) brought me to this restaurant, and we had a great time.
I ordered the pasta special which was a spaghetti in a creamy and flavorful white sauce (soy milk based), with fresh basil, and veggies. It was very delicious, though I wished there had been more veggies in there to balance the pasta.
For dessert I had the chocolate scone. It was amazing so I took a kabocha one to go. I really regret not buying 10. Jiyugoaka is a fabulous must-visit part of Tokyo, but it seemed to take us forever to get there. If it weren't so far I would definitely go back for more scones for the airplane ride home.
Pros: Delicious, Great atmosphere, Lovely staff
A change in pace - Edit
T's TanTan at Tokyo Central Station is famous amongst vegetarians in Japan. It is one of the very few places that sells vegan ramen and it is located in the very heart of Tokyo. However, the restaurant at Tokyo Station is merely the little brother of T's TanTan in Jiyugaoka.
After many good experiences in Tokyo Station, I wanted to try the real thing. Jiyugaoka isn't exactly a popular area for tourists, but the restaurant is less than 5 minutes by foot from Jiyugaoka station.
Compared to the Tokyo Station, the restaurant in Jiyugaoka is a world apart. In Tokyo vegan fast food is served at a fast pace. Waiters are always running, people are queueing outside and the lights are bright. T's TanTan Jiyugaoka is located in a basement floor. The mood is mellow, relaxed and jazz music is playing. This is like going from fastfood to slow food!
The most important reason to try the Jiyugaoka branch is the change in menu. At Tokyo Station only ramen is sold, in Jiyugaoka the menu is much more extensive. However, the menu is also more confusing. We selected our meals on the website, but it turned out the menu was changed and the website wasn't updated yet. Also, the English menu differs from the Japanese one. Once we made a choice, many dishes were sold out so we had to pick something else.
The portions are small, yet tasty. I started with the "hamburger" which is fact is just a piece of fake meat dressed in some sauce and onion rings. It is not a main dish like the menu suggests. My friend ordered pasta in tomato sauce which she raved about. We continued with fried chicken (tofu) in mayonaise, which also comes in very small portions. Finally we had gyoza which was the most tasty of the evening, but still not very satisfying. However, the total price of the meal adds up quickly by ordering so many small meals.
We left T's TanTan Jiyugaoka with mixed emotions. It differs so much from the Tokyo Station restaurant that only the name and a part of the menu overlap. Yet, the quality was fine and it does offer some welcome variety. Hopefully next time less items are sold out...
Pros: differs from the usual vegan meals, relaxed atmosphere
Cons: small portions, high prices, many meals sold out, english, japanese en web menu differ
One of the best in Tokyo - Edit
The location on the Happycow map is not correct. It is one block further away.
The food is excellent! Completely vegan except for honey (declaration on card). Style is western / chinese.
Creamy salad and mayo chicken were our favourites.
Pros: Excellent Food, Friendly Staff
Cons: Honey in chocolate Cake
Good food off the beaten path - Edit
First and foremost the map is incorrect! After you walk past Mizuho bank (to your right) continue past an intersection and find the Luz plaza. Had a very late lunch here. They have a lunch set from 11am-3pm. And I got the lunch set for 1800 yen. Salad, an extra appetizer (I choose pumpkin), the main dish (vegetable curry) and a choice of tea or coffee. The lunch set makes it easy to order even if you can't read Japanese.
Servings are not big but tasty. The curry was a bit salty that day. Cozy atmosphere inside. Not too loud. Next time I'll try the tantanmen and compare it with T's Tantan (sister shop in Tokyo Station).
Pros: inexpensive, a bit out of the way
Cons: good food, friendly staff, cozy atmosphere
The best place for dinner! - Edit
We went here for dinner several times during my visit to Tokyo. The staff were incredibly friendly and helpful, and many spoke English. The menu was clearly labelled to identify dishes including honey, soy, ginger and other ingredients that might not be suitable for some diners. Food was always beautifully presented, service was helpful but not overbearing, and the desserts are to die for! Definitely try the chocolate parfait!
Pros: Chocolate parfait!, Friendly, helpful staff, Relaxing atmosphere
Wonderful food, welcoming and informal - Edit
Visited with a local who comes here regularly for the reliable, beautifully prepared vegan dishes. The salad is beyond reproach and the dessert (a layered affair like the one pictured) was fresh, bewitchingly creamy and fruity - am weeping gently as i type. Cannot wait to return.
Pros: Vegan, Fresh, Welcoming
Nice little place - Edit
Have been here a few times, they do a set lunch menu with a salad, main, pudding and drink for about 1500 yen, it's a little more expensive in the evening. The vege meat chunks in sauce for a starter is really tasty. No English menu, but every dish has a photo, and it's all vegan so there's nothing to worry about.
Pros: Good value set menu, Nice decor, Nice trendy area
Cons: Out of central Tokyo
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text: Seller: honitonclocks (8,119) 99.8%, Location: Honiton, Ships to: Worldwide, Item: 262704175372 From the "Honiton Clock Clinic" in Devon, a family run, well established buisness offering the general public a long needed service, restoring and renovating clocks, barometers (aneroid and mercurial), barographs, music boxes, and much much more to a traditional style. We are having a stock clearance sale and when the stock is gone, we will no longer be making or selling this item again. So don't miss out. LAST CHANCE BeFORE CHRISTMAS. What do I get LIMITED STOCK10 x Wall HangingVintage Old StockSilver Finish HangersThat's 10 for only £1.45 or that's a Bargain!Stock Now LowThese are from old stock.The hanger is 31mm long with a7mm diam. holeThey are Not magneticThey have a good silver finish.for hanging barometers, wall clocks, brackets & pictures etc.More to followThere are more clock and barometer parts and salvage to follow.We are also going to clear out old stock items from the barometer parts range Look to my other listings for other clock, barometer & barograph parts etc If you require any further assistance please do not hesitate to phone during working hours on 01404 47466 Condition: As you see in the pictures.LAST CHANCE BeFORE CHRISTMAS., Age: Vintage


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