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York has a population of 40,862 and is located in York county.
Chef schools in York charged students an average tuition of $14,097.00 if they were Pennsylvania residents, and $15,665.00 if they were non-residents, during the 2009 - 2010 school year.
Books and supplies for chef schools in York cost an average of $1,514.00. The average cost for room and board for students living on campus at chef schools in York was $8,080.00. The average cost for students living at home was $2,241.00 for the 2009 - 2010 school year. There are two chef colleges in York for students to choose from. Chef programs in York reportedly graduated 82 students in the 2008 - 2009 school year.
|Average Salary
|Number Employed in City
|Chefs and Head Cooks
|First-Line Supervisors/Managers of Food Preparation and Serving Workers


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FREE SHIPPINGon Orders over $75 (Does not apply to bikes/fitness equipment & oversize packages)
Southside - Megastore312-794-41552540 S WabashM-F 11-7Sat 10-5, Sun 12-5
Northwest - Megastore773-282-02023255 N. MilwaukeeM-F 12-8Sat 10-5, Sun 12-5
Northside773-281-22633712 N. HalstedM-F 12-8Sat 10-5, Sun 12-5
Near North312-266-1700219 W. ErieM-F 11-7Sat 10-5, Sun 12-5
South Loop312-360-0020811 S. DesPlainesM-F 12-8Sat 10-5, Sun 12-5
Brooks Slender Leather Grips feature vegetable-tanned leather tape, and are designed to offer an alternative performance option for the user, while maintaining the standard for sustainability set by the Plump Grips, allowing the user to replace worn parts if necessary. The design incorporates an aluminum shell around which the bar tape is wrapped in the manner of traditional handlebar tape. The leather is then held in place by aluminum and steel clamps which can be removed in the event that the tape requires replacement. The tape is made from the same vegetable-tanned leather used for Brooks Saddles and natural cork. Made in Italy.
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Temptation Cancun Resort offers 428 accommodations in three categories- Deluxe rooms, Jacuzzi Suites and Temptation Suites – all featuring exquisite, stylish, modern décor and private terraces or balconies boasting spectacular ocean or garden views.
• 342 Deluxe Rooms offer accommodating options between one king bed or two double beds, each with a garden or an ocean view. They have highlighted décor with white, red and silver accents along with luxurious furnishing such as duvets, black outs, drapes and full length mirrored sliding closet doors. Room amenities include: flat screen TV; individually-controlled air conditioning; direct-dial telephone; vanity mirrors; coffee maker; hair dryer; iron and ironing board; mini bar (soft drinks, water, juices and beer – stocked daily); safety deposit boxes; electronic door locks.
• 30 Jacuzzi Suites offer one king size bed, a terrace with pool view and an outdoor Jacuzzi. Every room includes a pull down privacy screen, modern décor that is highlighted with white, red and silver accents, artwork, luxurious furnishing and full length sliding closet doors with mirrors. Bathrooms are equipped with fixtures, makeup and vanity mirrors, decorated with pearlescent red glass tiles, ceiling and a high rain showerhead. Room amenities entail: screen TV; iPod dock, individually-controlled air conditioning, direct-dial telephone, coffee maker, hair dryer; iron with ironing board, mini bar (soft drinks, juices and beer - stocked daily); safety deposit boxes and electronic door locks.
• Drops of Love Package, offered exclusively for our Jacuzzi rooms, includes: room service for breakfast, lunch and dinner, fresh strawberries covered with chocolate, a fruit basket accompanied with a bottle of sparkling wine, daily petit fours, a lobster dinner for two in the privacy of your room, a dozen roses, couples massage and the Drops of Love Experience where your Jacuzzi will be prepared with selected essences, oils, candles and incense by your personal butler.
Talk to a specialist
Call 020 7644 1755 to speak with our award-winning travel consultants.
Opening hours 09:00 - 21:00 GMT


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Join us and see what happens when artists create together!
Located in Nashville, TN
Progressive Studio Dinner
Thursday, March 23rd, 2017 6-8:30pm
Visit with over 25 artists on Campus as you move from studio to studio while enjoying homemade food and drinks. You will get to engage with local artists while they […]
Basic Drawing Class for artists
Basic Drawing Class with Nan Jacobsohn
Saturday, March 18th, 2017
9:00am-3:00pm in Studio B, Cost $55
Learn how to translate drawing skills to other art mediums.
Supplies needed: sketch pad, pencils & a super fine marker
Call 615-242-0346 to register […]
Torch-fired enamel jewelry class
Torch-fired Enamel Jewelry Class with Pam Wilson
Saturday, March 11th, 2017
10:00am-2:00pm in Studio B, Cost $85
All materials are included. Learn the basics of torch firing enamels on copper using a Mapp gas torch. Attendees can […]
The Clay Lady speaks on "The reality of being an artist"
"The reality of being an artist" , by Danielle~The Clay Lady courtesy of Creative Mornings Nashville
We are proud to be a part of Creative Mornings Nashville, a breakfast lecture series for the creative community. In […]


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Moroccan Cooking Class in Fez City
Duration: 3 hours
Explore the Moroccan cooking class with us in the imperial city of Fez. Enjoy your time and learn more about its outstanding cuisine.
FesSee all 22 tickets & tours
Want to discover all there is to do in Fes? Click here for a full list.
My friend and I had an absolutely fantastic time on this cooking course. We learnt how to make Moroccan bread, saw where they take it to cook it and then also made tagine, 2 types of salad and flan. We felt very welcome in their home and would definitely recommend!


text: originally posted in:True Guardians of Destiny 8/20/2014 8:20:28 AM 0 0 Vader316 so has your choice changed? Hunter 1 Titan 2 Warlock 4 So we've played the beta has your choice changed let's find out #whowillyouchoose Comment Reply Start Topic Report Add more answer options B I U Quote Link Named Link Spoiler Armory Forum Category Destiny Feedback Help Community Recruitment Gaming OffTopic Forum Sub-Category Post a Poll Question Post Cancel Edit Create Fireteam Post Play nice. Take a minute to review our Code of Conduct before submitting your post.


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Running late for school or have errands to run, but don't want to look like a walking zombie while doing so? We all have those days! I've developed an easy makeup routine that works well for busy schedules and have included a video tutorial to help you out. Below are my top tips for getting out of the door in a hurry, while still looking and feeling beautiful.FTC Disclosure: This post contains affiliate links, which means we'll receive a small referral fee from purchases at no cost to … [Read more...]
Where to Apply Bronzer for a Sunkissed Look (VIDEO)
FTC Disclosure: This post contains affiliate links. You can read our affiliate policy here. Pale is pretty, but let's face it…there are times when it's fun to look like a sunkissed beach babe. (Or at least create that illusion!) That's when self-tanner and bronzer can come in handy. I've created a "Get Ready with Me" video so you can watch me apply my makeup from start to finish -- including my bronzer routine. I'll demo where to apply bronzer so you can duplicate the look to create your own … [Read more...]
LOOKBOOK: Brigitte Bardot Makeup Tutorial
I'm participating in a fun makeup challenge on Instagram called #100daysofmakeup. You can go on Instagram and search for the hashtag to see sample looks other people have created. I thought it would be a fun thing I could do during the summer months that would challenge me to create some unique looks! For the first one I thought I'd recreate Brigitte Bardot's sultry makeup and voluminous hair, since she has such an iconic look.The key ingredients to Brigitte Bardot's look are: - … [Read more...]
Winged eyeliner has a bad reputation of being difficult to master, but it just takes a little practice and a few handy tricks to get it right! Since the three main topics I'm asked about most often are my cat eye, my lashes, and my brows, I decided to debut my first makeup tutorial video showing how I get my cat eye! Be sure to read to the bottom of the post to get my favorite game-changing tip for a perfect wing.Just bein' silly. :)So, what do you need? - Eyeliner of your choice (I … [Read more...]
Holiday Retro-Glam Makeup Tutorial
If you're inspired by Old Hollywood and classic beauties like Grace Kelly, then this retro makeup tutorial is perfect for you. The classic cat eye, strong brows, bold red lip, and pin curls all combine for one stunning signature look. If you're planning on wearing anything gold and sparkly for NYE, this makeup look would pair perfectly with that combo!When in doubt, you can't go wrong with classic (that's my motto, at least).FTC Disclosure: This post contains affiliate links, which … [Read more...]


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Located in Pratumnak Hill within a 5-minute walk of Yin Yom Beach, Golden Cliff House is within a 15-minute stroll of Dongtan Beach. This 47-room, 3.5-star hotel has conveniences like a restaurant, a bar/lounge, and a rooftop terrace. It's also close to Mini-Golf Pattaya and Pattaya View Point.
Enjoy a leisurely bite to eat at the onsite restaurant, or have a drink at the bar/lounge. For your convenience, breakfast is available for a fee.
The 47 rooms are air-conditioned and have an array of amenities, including refrigerators, minibars, and free newspapers. For entertainment, guests can enjoy TVs. In-room massages are available.
Property features
Golden Cliff House features a sauna, a rooftop terrace, and free WiFi in public areas. Front-desk staff are standing by 24/7 to assist with any requests. Additional amenities include laundry facilities and a garden.
- Free WiFi in public areas
- Onsite dining
- Rooftop terrace
- Laundry facilities
Golden Cliff House
Hotel Amenities
Hotel Amenities
The hotel offers a restaurant. A bar/lounge is on site where guests can unwind with a drink. High-speed wireless Internet access is complimentary. This Pattaya hotel also offers a sauna, a rooftop terrace, and a garden.
- Total number of rooms - 47
- Number of floors - 4
- Number of buildings/towers - 2
- 24-hour front desk
- Breakfast available (surcharge)
- Laundry facilities
- Garden
- Bar/lounge
- Sauna
- Rooftop terrace
- Restaurant
- Free WiFi
Family Friendly Amenities
- Free Wi-Fi
- Laundry facilities
- Refrigerator
Available in some public areas: Free WiFi
Room Amenities
Golden Cliff House offers 47 air-conditioned accommodations with complimentary newspapers. Guests can make use of the in-room refrigerators and minibars.
- Air conditioning
- Refrigerator
- Minibar
- Television
- Free newspaper
- In-room massage available
Where to Eat
Golden Cliff House has a restaurant on site.
Nearby Things to Do
Recreational amenities at the hotel include a sauna.
If you have requests for specific accessibility needs, please note them at check-out when you book your room.
Hotel Policies
Minimum check-in age is 18
Check-in time starts at 2 PM
Check-out time is 11 AM
Payment types
Children and extra beds
- Children are welcome.
- Pets not allowed
You need to know
Extra-person charges may apply and vary depending on property policy.
Government-issued photo identification and a credit card or cash deposit are required at check-in for incidental charges.
Special requests are subject to availability upon check-in and may incur additional charges. Special requests cannot be guaranteed.
No rollaway/extra beds available
No cribs (infant beds) available
- New Year's Eve (31 December) Gala Dinner per adult: THB 2500
- New Year's Eve (31 December) Gala Dinner per child: THB 1250 (from 2 to 12 years old)
Optional extras
- Breakfast fee: THB 300 per person (approximately)
Hotel Name
- Golden Cliff
- Golden Cliff House
- Golden Cliff House Hotel
- Golden Cliff House Hotel Pattaya
- Golden Cliff House Pattaya


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Faculty Development Initiative: Phase II
The document provides an outline of the first and second phases of MERLOT's faculty development initiative. Phase II includes: 1. Continue workshops and conference presentations -which builds awareness and some skills. 2. Develop and conduct online courses on MERLOT- which develops robust skills 3. Develop MERLOT-Teaching and Technology collection and Editorial Board to build collection of online resources - which enables efficient and effective development of workshops, courses, and... More
http://info.merlot.org/merlothelp/index.htm#partner_benefits.htm to see how your institution can join MERLOT.This item is available for viewing by the MERLOT Leadership Community. The Leadership Community is comprised of MERLOT Partner Project Directors, and MERLOT Discipline Editors. If you are not a MERLOT Partner member, please visit
Material Type: Presentation
Technical Format: HTML/Text
Date Added to MERLOT: February 03, 2012
Date Modified in MERLOT: February 03, 2012
Submitter: Gerry Hanley
Reviewed by members of Editorial board for inclusion in MERLOT.Editor Review (not reviewed)
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Pick a Bookmark Collection or Course ePortfolio to put this material in or scroll to the bottom to create a new Bookmark CollectionName the Bookmark Collection to represent the materials you will addDescribe the Bookmark Collection so other MERLOT users will know what it contains and if it has value for their work or teaching. Other users can copy your Bookmark Collection to their own profile and modify it to save time.Edit the information about the material in this {0}Submitting Bookmarks...Select this link to open drop down to add material Faculty Development Initiative: Phase II to your Bookmark Collection or Course ePortfolioSelect this link to close drop down of your Bookmark Collection or Course ePortfolio for material Faculty Development Initiative: Phase IISelect this link to open drop down to add material Faculty Development Initiative: Phase II to your Bookmark Collection or Course ePortfolio
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Bret Michaels is "doing well" after undergoing an emergency appendectomy, his rep said in a statement.
The rocker and current Celebrity Apprentice contestant was rushed into surgery in San Antonio at 1 a.m. Monday after suffering severe stomach pains and what was assumed to be the flu all day Sunday. Doctors later determined the singer had acute appendicitis.
"According to doctors, Michaels, who remains in the hospital, is doing well and beginning the recovery process," the statement read.
The surgery forced the 47-year-old to cancel his Sunday performance at Sea World, which has since been rescheduled for Oct. 1.
"Michaels, who has been known to perform under extreme conditions that would make most performers cancel, will unfortunately have no choice but to reschedule some of his April tour dates," the statement continued.
The new dates will be posted on his website in the coming days.


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News By Tag
* Car Audio
* Mobile Video
* Marine Audio
* Car Alarms
* Remote Car Starters
* Navigation Systems
* Device Integration
* Window Ti
* More Tags...
Industry News
* Car audio
* More Industries...
News By Place
Industry News
Mobile Electronics Shop in San Antonio Hires Leading SEO Pro to Boost Accessibility for Locals
Soundmaster Tint & Alarm, Inc., a one-stop shop for mobile electronics in San Antonio, is pleased to announce its recent SEO program developed in collaboration with Prospect Genius.
Phone: (800) 511-8169
Address: 5563 De Zavala Rd, Suite #140, San Antonio, TX 78249
Web site: http://mobile-
Soundmaster Tint & Alarm, Inc., a one-stop shop for mobile electronics in San Antonio, is pleased to announce its recent SEO program developed in collaboration with Prospect Genius, a leading Internet advertising firm. With the introduction of this new search engine optimization plan, Soundmaster Tint & Alarm, Inc. makes it easier than ever for local Texans to locate the business's Web site and their all-inclusive menu of mobile and marine electronics, from car DVD players and in-dash navigation systems to backup cameras and remote car alarms.
Nearby residents in need of mobile electronics and accessories will now be able to use Bing, Google, Yahoo!, and other available search engines to avoid the hassle of sifting through multiple online listings and streamline their access to Soundmaster Tint & Alarm, Inc. So whether searchers need iPod integration in Alamo Heights, vehicle security in Castle Hills, or window tinting films in Olmos Park, Prospect Genius can help them connect to this premier, family-owned car audio shop with more than 18 years of experience in the trade.
A leader in local online advertising, Prospect Genius uses the latest SEO strategies and monitoring methods to assist small businesses across the country in their Internet marketing efforts. By enhancing the online visibility of Soundmaster Tint & Alarm, Inc., PG is able to capture the attention of more potential customers and track the behavior trends of visitors to their site. This type of insider Web information allows Soundmaster Tint & Alarm, Inc. to better understand the needs of the mobile electronics customers they cater to throughout San Antonio and the entire metro area.
"It's our pleasure to work with such outstanding local businesses as Soundmaster Tint & Alarm, Inc. to help them reap the rewards of effective online advertising,"
Soundmaster Tint & Alarm, Inc. is a fully licensed, bonded, and insured mobile electronics sales and installation shop based in San Antonio, Texas. In business since 1993, they offer a complete showroom stocked with a wide range of car audio video, window tinting, and other customization products.
# # #
Serving San Antonio TX, Alamo Heights TX, Balcones Heights TX, Castle Hills TX, Leon Valley TX, Live Oak TX, Olmos Park TX, Since 1993
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I will create work you will love(2)
About This Gig
Frequently Asked Questions
What if I'm not happy with the final product?All of the packages include 4 revisions to help ensure the work I do is up to your highest standards and if you're not happy with it even after 4 revisions then you can purchase additional revisions at a low cost.
Do you offer any other services besides branding design?I offer a variety of services! Just recently I've been working on a variety of photo editing and flyer designs! If you have any questions you can contact me and pitch me your design ideas and ask any questions you want!


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With Instructables you can share what you make with the world, and tap into an ever-growing community of creative experts.
Tell us about yourself!
Free and Cheap Clay at home
Rainbow Loom Goldfish Charm
Make your own Teepee
Flower Vase in Magazine Paper
Join 2 million + to receive instant DIY inspiration in your inbox.
© 2016 Autodesk, Inc.


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Sophia says of her baby boy, ''I didn't know that I could ever love anyone this much.'' As a mother of four and a grandmother of eight, I understand her feelings.
Those who are appalled that an older woman wants to bear a child saw nothing amiss when Tony Randall and Ben Bradlee fathered trophy children with women young enough to be their daughters or granddaughters.
The outrage at Sophia and other brave women who love children and who want to bear them past menopause is the chauvinism of those who guard male privilege.
Lee De Cesare
Madeira Beach, Fla.Continue reading the main story


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The 10 most recommended products by Fangocur at a glance
Alleviates impurities & rosacea
- Removes deposited waste products
- Protects against dehydration
- Inhibits inflammation
In stock
Highly effective against skin impurities
- Anti-inflammatory
- Especially effective against acne, abscesses & inflamed skin
- Regulates the metabolism
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Soothes irritated skin
- Regulates lipid metabolism of the skin
- Especially suitable for acne, rosacea and pimples
- Helps prevent skin irritations
In stock
Soothing cleansing for face & body
- Alleviates skin irritations
- Removes metabolic waste products
- Does not dry out the skin
- Also suitable for intimate hygiene & shaving
In stock
Gentle care for problem skin
- Inhibits inflammation
- Regulating and deep cleansing
- Ideal for skin affected by eczema & psoriasis
In stock
For the gentle removal of facial masks
- Finely porous
- For gentle cleansing
- Size: approx. 6 - 10 cm
In stock
Mild shampoo
- For energy & volume
- Cleanses, conditions & strengthens the hair & scalp
- Anti-inflammatory
In stock
Alleviates cold sores & aphthous stomatitis
- Free from chemical ingredients
- Strengthens the oral mucosa
- With calming effect
In stock
Gentle cleansing for problem skin
- Ideal for skin suffering from eczema & psoriasis
- Anti-inflammatory
- Regulates the moisture balance
- Also suitable for cleansing hair
In stock
Gentle peeling effect without irritating the skin
- Coarsely porous
- Increases blood circulation
- Size: approx. 15 cm
In stock
All prices incl. VAT.


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Hear ye, hear ye… Please join us for a royal shower feast — a sweet baby knight will soon be here! This noble baby knight shower invitation features a castle, crown, hearts, and stars on a scroll-like graphic. Completely change the co-ed royal shower wording to your shower needs as desired, to suit any occasion or style of the coming babe. We can also customize the boyish green & blue colors, graphics, and fonts to your taste.
Simply put your requests in the notes field when you personalize this card here: Prince Baby Shower Invitation.


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There are two Japanese food items that have been making waves here in the Philippines — tonkatsu and ramen. And then I find a place that offers both — Tampopo in Greenhills! Like the international bakery chain Eric Kayser, Tampopo was brought to the Philippines by Chris Tiu and company.
Tampopo, a Japanese-owned ramen and tonkatsu franchise from Singapore (yes, Singapore!) opened in Manila sometime last December. It has been touted as Singapore's #1 ramen and recognized as one of Singapore's top restaurants.
As usual, our cook took the day off and so we had to go out for lunch last Sunday. Tampopo in Promenade has an adjoining area dedicated to Red Mango, a Korean yogurt chain which Chris Tiu also franchised. You can order desserts from Red Mango after a meal at Tampopo.
I wonder how Tampopo would fare against the other ramen and tonkatsu places…
We were served water while waiting for our orders. I think it's good that they leave the pitcher with you so you don't have to keep asking for refills.
I ordered a Deluxe Hakodate Ramen (P420, pictured above). According to the menu this uses imported Hokkaido ramen. The server told me that the milky white broth is a mix of chicken and seafood. It's supposed to be one of the bestsellers too. This ramen had slices of pork, seaweed, bamboo shoots, a pat of butter, corn kernels, tiny shrimps, and a ramen egg (aji tamago).
The milky broth was quite bland despite the fact that I mixed in the butter thoroughly. The ramen egg was tasty and had a runny golden yolk. This is one of the better aji tamago I've tried although Ikkoryu's is still the best for now. The noodles were firm yet chewy, quite heavy in the tummy actually. The pork slices were kind of dry and the taste reminded me of Masuki's asado. I was unable to finish the entire bowl. Next time I think I should split an order of ramen with someone.
Daughter ordered Children's Set A – Ebi Fry and Tonkatsu (P240, pictured above). Rice is shaped into two pieces of onigiri and served with potato salad, hard-boiled egg, shredded lettuce, cucumber slices, a big piece of deep fried shrimp, and a few slices of tonkatsu (pork cutlet). There's also Yakult and tartar sauce on the side. It's pretty hefty for a child and the price is very reasonable.
Son ordered Special Premium Katsu Don (P350, pictured below) and was given a small dish of sesame seeds to grind.
Not bad for P350, right? You get a big bowl of rice topped with yummy tonkatsu, egg, and shredded lettuce, plus a bowl of miso soup, some pickles, and fresh fruit slices for dessert. It's a complete meal and son wolfed it down immediately after it was set in front of him.
We also ordered Sui Gyoza (P150 for 6 pcs). It's supposed to be spicy as it's shown to be drenched in a mix of chili oil and gyoza sauce in the menu but we asked for the sauces to be served on the side. I skipped the chili oil and just ate it by dipping a piece in gyoza sauce. Chewy wrapper, meaty filling, and more importantly not greasy since it was steamed. Nice.
Hubby had Hokkaido Seaweed Soba with Special Sauce (P240, pictured above) because he wanted something light and non greasy. He was happy with it, I forgot to have a taste lol so I can't describe it.
He opted for an ala carte order of Pork Loin Yanagawa Premium (P220, pictured above) to go with his cold noodles. It's pretty big for one person so I had a couple of pieces. It was surprisingly good — the pork was tender and I liked how they cooked it in egg and sweet-savory miso. I'd say the tonkatsu is about Yabu-level in terms of taste and price.
I've actually heard a lot of negative feedback about Tampopo prior to our visit so I didn't have high expectations despite the claim of being one of Singapore's top restaurants. Our lunch experience was pretty average. The ramen wasn't exceptional but in general everything was okay. Service was good and the place was nice and cool despite the sweltering summer heat outside. I found the prices to be reasonable too. I would probably go back if just to try a different bowl of ramen.
G/F Promenade 3
Greenhills Shopping Center, San Juan City
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Teenage Mutant Ninja Turtles: Out of the Shadows Plot Summary:
The Shredder (Brian Tee) escapes police custody with the help of advanced technology, but in doing so, comes into contact with a war lord from another dimension who wants to bring his ultimate weapon to planet earth. To combat the Turtles, Shredder enlists mad scientist, Baxter Stockman (Tyler Perry), to create two new mutants to demolish his old enemies. The special mutagen may also contain life changing properties for the turtles, as they try and unite to save the city once more.
Teenage Mutant Ninja Turtles: Out of the Shadows can best be described as not being able to look at the ark of the covenant. While this Turtles movie demolishes the first film, it's very much a gigantic turtle tease. Don't get me wrong – if you're a die hard Turtles fan like myself, you need to see this film. This movie gave me images and characters that I literally had dreams about when I was a kid. If you're in my age bracket, this is what we all thought Teenage Mutant Ninja Turtles III was going to be. The problem is they don't go all the way, to the point where it drove me to the brink of madness. They were so close. Even with all my Ninja Turtle nitpicks though, I'd be lying if I didn't say I was totally and utterly satisfied with this movie. To put it bluntly, this is a damn good Turtles romp.
Even with my strong dislike for the first film, they still built a good foundation. The turtles had chemistry, and they nailed the characterizations. The problem is they needed to tone down Michelangelo (Noel Fisher). I guess they listened. No longer is his dialogue 85% hitting on April (Megan Fox). Michelangelo was a lot funnier because his jokes weren't constant. But aside from Michelangelo, they get the heart of what the Ninja Turtles is. It's four very different brothers who need to unite as a team. That's the Ninja Turtles, and that's why this film works. They also introduce a strong conflict that hasn't been explored very much in Ninja Turtles lore – the desire to be human. For all its juvenile flaws and Michael Bay-isms, they kept the turtles pure. There's actually some subtle character development here, and even some memorable dialogue, especially from Leonardo (Pete Ploszek), who's kind of a dick. All the turtles deal with not being accepted in different ways that hold true to their personalities. If this didn't have to placate to kids, the writers could have really dived into something special. I understand it's a kid's movie though, and I appreciate what we got. Even with all the fan service, the Turtles were the best part, and that's how it should be. I have no complaints with anything involving the Ninja Turtles in this movie.
Before we get to the newbies, my biggest rant against the previous film was Shredder. He completely sucked can openers. Thankfully, he's much better, but they still dropped the ball. He barely gets anything to do, and is completely tossed aside at the end. While they wrote nothing for Shredder, Brian Tee did a great job bringing an intense presence that the character sorely lacked last time. It's still not everything I hoped for, but Shredder definitely gets the Most Improved award. Splinter (Tony Shalhoub, voice) was also underutilized, which pisses me off, as he's my favorite character! Come on! When we did see him though, he was well written, and definitely had some great stand out moments. There just needed to be more. Megan Fox was also much improved as April, and just seemed to have more fun with it. I'm not saying she's Katharine Hepburn, but this movie at least proved she's capable of smiling. Will Arnett is also back as Vernon Fenwick, who's perfectly fine, but he's the one guy who was better last time around. He just seemed funnier. The movie in general could have been funnier, although there is one hilarious prank involving Splinter and Casey Jones (Stephen Amell).
Speaking of Casey Jones, you want to hear about allllllll the fan favorite newbies, right? I enjoyed Amell in the role, but if you're expecting Oliver Queen as Casey Jones, it's not that at all. Casey Jones was way more chipper than I thought he'd be, but when he fights, it gets nasty. They could have done more with the character, but Amell's charisma really elevated what was on the page. Bebop (Gary Anthony Williams) and Rocksteady (Stephen "Sheamus" Farrelly) are Bebop and Rocksteady. They run around like morons and smash things. I got to say though, they were funnier as humans. Gary Anthony Williams legitimately made me laugh as Bebop. As the rhino and warthog, the jokes never got too bad, aside from one horrible fart gag. It happened. It is what it is. Tyler Perry as Baxter Stockman was hilarious in a Mystery Science Theater 3000 kind of way. The dude just went for it, and completely over acts. I loved every minute of it. You're either sold on his first laugh, or you're not. Laura Linney also pops up as a police chief. She doesn't do much, but it was nice to have her.
Enough about Laura Linney though. Let's get to it. This is it. If you're a Ninja Turtles fan, you know what this moment means – I've seen Krang in a live action Ninja Turtles movie. There's no build up whatsoever to his first appearance. It just happens. I couldn't even contemplate the first few seconds he was on screen. I never thought this day would come. So, how was he? Overall, pretty damn good. The look was perfect. This is where the film is a giant tease though. Krang's body – good, not great. Krang's voice – good, not great. What's interesting about that is Fred Arminsen was attached for a long time, but had to back out at the last minute. Brad Garrett was put in the role literally a few weeks ago. It annoys me that Krang's voice felt rushed. It's essential to the character. I'm not saying it was bad. It just could have been better.
If seeing Krang was my first childhood dream, I also got my second. The Technodrome. Look, I'm not spoiling anything here. It's crystal clear in the trailer. It's the damn Technodrome, alright! This is what really pissed me off while watching the movie. The Technodrome looks like the Technodrome. It's exactly how you'd imagine. The problem is you never see one full shot of it in all its glory. What complete bull shit! It's like going to a Patriots game and seeing Rob Gronkowski run around the field, but he never catches a pass! I'm guessing this was a budget problem, but it's still infuriating. WHAT A TECHNO-TEASE!
For all my Ninja Turtle-centric complaints, I had an absolute blast. Yes, it has several scenes that remind you Michael Bay put his grubby hands on it, such as the fart joke, and an April scene where she wears a suggestive outfit while a crappy pop song blasts through the speakers, but that's really it. The action sequences are pure pleasure. It was quite a thrill to see Bebop and Rocksteady go at the Turtles. And even though it's very fan servicey right up through the end credits, this is a fun summer movie that parents will be just fine with while they get dragged by their kids. If you're a life long turtle fan though, this is required viewing. Aside from the 1990 film, this might be the best Turtles movie ever made. If for nothing else, they're good to go for one hell of a third movie, where I expect to see the Turtle film to end all Turtle films. There are no excuses now. They have all the pieces, or shells rather.
Rating: 7.5 out of 10 (Very Good)
Daniel Cohen is the Film Editor for Pop-Break. Aside from reviews, Daniel does a weekly box office predictions column, and also contributes monthly Top Tens and Op-Ed's on all things film. Daniel is a graduate of Bates College with a degree in English, and also studied Screenwriting at UCLA. He can also be read on www.movieshenanigans.com. His movie crush is Jessica Rabbit. Follow him on Twitter @dcohenwriter.


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A new professional football league is coming in the summer of 2018.
Just like its WFL, USFL, XFL and UFL predecessors, the founders of the Pacific Pro Football League say they have a new wrinkle to make this upstart a viable offering.
Donald Yee, who also serves as Tom Brady's agent, is one of those founders along with former NFL wide receiver Ed McCaffrey and others.
PPFL's advisory board includes Mike Shanahan, former NFL executive Jim Steeg, former NFL game official Mike Pereira, political strategist Steve Schmidt and ESPN's Adam Schefter.
The idea behind the four-team league based in southern California is to pay college-age players who want to bypass the NCAA and begin earning money professionally.
Players will earn a salary with benefits valued at an average of $50,000. The league said it will be gimmick-free when it comes to football rules and style of play aside from some modifications to aid player safety. Teams will play eight games.
"It has become very clear to me, particularly over the last 15 years or so, that emerging athletes from middle school on have become much more specialized and even professionalized in their training and protocols — in becoming good at whatever sport they choose to become good at," Yee told Vice Sports. "In every other sport you can think of, even global sports, young and emerging talent is about to be professional directly from high school or even younger. The only outlier is football. I felt it should no longer be an outlier."
Start-up funding has been secured but the league is looking for sponsors and venues.


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I know, I know- that little silver hatchback up there is a 2016 Scion iM, but it won't be for long. That's because Scion, as you may know by now, is dead. To fulfill Scion's initial mission ...
May 27th, 2016Blog
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Goal! 2
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Goal! 2 by Robert Rigby
Book DescriptionSantiago has made his mark in the UK Premier league as a magic midfielder with Newcastle United. But European football now beckons and he finds himself playing alongside stars such as Beckham, Raul and Zidane for Real Madrid. But playing in the UEFA Champions League can bring new pressures - new challenges: fighting to keep his place in the squad, trying to resist the temptations surrounding a successful footballer, aiming to maintain his relationship with his girlfriend back home. Sometimes dreams can turn sour ...
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Book DetailsISBN: 9780552554084
(198mm x 129mm x 17mm)
Pages: 272
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Publish Date: 23-Jan-2007
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Wolfblood: Pull of the Moon, Paperback (December 2015)
Fourteen-year-old Maddy lives with her mother and father high in the moors of the beautiful Northumbrian countryside. Her Wolfblood nature - and that of her parents - is her most closely guarded secret.
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On a snowy night on Stoneybridge Moor, three wild wolves pursue another lone wolf, closing in on him. Meanwhile, Maddy and her parents take shelter in their underground 'den', away from the full moon and the danger of transforming into Wolfbloods in the open air.
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As well as writing the novelization for the first GOAL! movie, ROBERT RIGBY is also the co-writer of the BOY SOLDIER series with Andy McNab. A professional screenwriter whose work includes scripts for Byker Grove, he has also run literacy, drama and writing projects, doing outreach work in Education Action Zone schools and writing and staging drama for and with young people. He is particularly interested in writing that appeals to reluctant boy readers. Most importantly, he is also a very keen football fan.
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iPhone apps
We´ve all used the Apple Remote application to control iTunes on our computers. Now, you can use Tunes to control another iOS device like iPod Touch*.FEATURES• Manage Now Playing playlist locally or remotely• Search and queue songs locally and….. Read more
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Photo By Niagara – via wikipedia
"Dear PoPville,
Photo By Niagara – via wikipedia
"Dear PoPville,
Honestly just move. DC is a city where it takes years to get a stop sign installed. I cannot even fathom the effort required for what you propose, and at best you might succeed (but I doubt it) in 5-10 years.
I have to agree with Rollout. I dont want to sound insensitive but move to a slower part of the city or out to the burbs if you want the quiet that comes from living in a cul-de-sac.
I live several blocks away but walk/drive past this intersection daily. It is a completely cluster. I think the traffic issues here and at 14th and Irving are largely DC USA driven, but the light at 16th and Park is incredible short and doesn't sync with the light half a block east.
That intersection is a mess, but you may have hit on the ONE thing that will motivate DDOT to make some changes:
"church services are interrupted,"
It's a Catholic church, so regular rules don't apply.
Don't forget that Kelsey Temple Church of God is on the same stretch or Park Rd..
DDOT is actually planning to put transponders into the buses that run along the 16th street corridor to do exactly this with signal lights. So it couldn't hurt to ask if there are any plans to do the same for emergency vehicles.
OP, I actually reached out to Elizabeth Horen in Nadeau's office about this issue in Oct of 2015 and this was the response she got (tl;dr: they know the technology exists but I don't see them moving on it anytime soon): "Thank you for the suggestion. We strive to ensure quick response times in emergency situations while protecting the safety of drivers, pedestrians and others with whom we share the road. While we do not currently have traffic light preemption systems like the one you mention, we are currently exploring that type of technology in consultation with the Department of Transportation (DDOT)."
The response she got from whom — DCFEMS?
Seems like this is something for which DDOT would be the primary agency, not DCFEMS.
Get rid of the onstreet parking on 16th. That's what makes this stretch slow to a crawl. And yes, once upon a time, I live not far away with a car.
This is right on. Eliminating the ability to park on 16th St. south of Piney Branch 24/7, with dedicated bus lanes, would solve many traffic problems.
That said, the OP lives in the wrong place for noise avoidance. I live just 4 blocks away and had no idea.
While I don't disagree with this sentiment, 16th isn't the issue here, it's Park. Much of Park is effectively one lane from 14th to 16th, and that's the choke point that snarls up traffic (and has an ambulance parked, sirens wailing, for 2+ minutes outside the homes there). Eliminating parking on Park might not solve the problem, but it couldn't hurt.
I live at 16th and Park and have a 5 month old. I agree that this would be great to have. Baby is a city kid, who sleeps through sirens, drilling concrete right next to us when we're out and about in the stroller…That being said, we'd love to move but can't afford to right now.
Infants are very adaptable to their environment. Adults are the ones who get worked up about this stuff. Mostly. I myself was a colicky baby…
These things are everywhere in MSP. When I moved here, I was pretty surprised to find out that not every city has them.
Former Holiday Inn at 35th and Wisconsin Ave, NW Thanks to all who emailed the Washington Business Journal story "Trader…
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North Cleveland Park gangsta.
Capitol Hill.
Capitol Hill. More details.


text: My father, who graduated from a private medical school in 1970, says that his tuition was ~$2500 during his last year of med school. In inflation-adjusted dollars, that would be $15,344 in 2016. However, Harvard's medical school tuition for 2016-2017 will be $58,050. He asked me to ask if anyone on this forum could help him understand why there has been a nearly 400% increase in tuition?


text:
Residence Inn Tallahassee North/I-10 Capital Circle
Service & facilities
|Earliest check-in
|Latest check-out
Service & facilities
Hotel facilities
- Reception (lobby)
- Elevator
- Hotel-owned car park
- Safety deposit boxes at reception
- Ice machine
Room facilities
- Cable TV
- TV remote control
- Radio
- Desk
- Telephone in the bathroom
In-house services
- Multilingual staff on hand 24 hours a day
- Washing machine for guests
- Express check-out
- Free daily newspapers
- Business center
Style of hotel and ambience
The Residence Inn Tallahassee North/I-10 Capital Circle is particularly suitable for extended stays. Its fully furnished suites have their own kitchen as well as separate areas for sleeping, eating, and relaxing. In the morning, enjoy a delicious hot breakfast alongside other guests in the Gatehouse, and participate in sociable evening events, which are held several times a week.
Hotel data
Hotel built in 1996, Last partial renovation 2009, Number of floors 3, Total number of rooms 78, Number of suites (separate rooms) 78, Hotel, Suite hotel, Golf hotel
Service times
Earliest check-in:
Latest check-out:
Accepted payment methods
- Diners Club
- Visa
- Eurocard/MasterCard
- American Express
- Japan Credit Bureau (JCB Intl.)
1880 Raymond Diehl Road, 32308 Tallahassee -
Located a 10-minute drive from the centre of Florida's capital, this suite hotel offers great connections to the I-10 and the popular Alfred B. Maclay Gardens State Park. Besides two renowned universities, Tallahassee is home to the impressive Florida State Capitol with a viewing platform on the 22nd floor.
- 8.12 km
- 15.33 km


text:
Baietti M.F.,Center for the Biology of Disease Leuven Belgium |
Simicek M.,Center for the Biology of Disease Leuven Belgium |
Abbasi Asbagh L.,Center for the Biology of Disease Leuven Belgium |
Radaelli E.,Center for the Biology of Disease Leuven Belgium |
And 7 more authors.
EMBO Molecular Medicine | Year: 2016
Activation of the RAS oncogenic pathway, frequently ensuing from mutations in RAS genes, is a common event in human cancer. Recent reports demonstrate that reversible ubiquitination of RAS GTPases dramatically affects their activity, suggesting that enzymes involved in regulating RAS ubiquitination may contribute to malignant transformation. Here, we identified the de-ubiquitinase OTUB1 as a negative regulator of RAS mono- and di-ubiquitination. OTUB1 inhibits RAS ubiquitination independently of its catalytic activity resulting in sequestration of RAS on the plasma membrane. OTUB1 promotes RAS activation and tumorigenesis in wild-type RAS cells. An increase of OTUB1 expression is commonly observed in non-small-cell lung carcinomas harboring wild-type KRAS and is associated with increased levels of ERK1/2 phosphorylation, high Ki67 score, and poorer patient survival. Our results strongly indicate that dysregulation of RAS ubiquitination represents an alternative mechanism of RAS activation during lung cancer development. © 2016 EMBO. Source


text:
Fatigue Fighter helps maintain healthy energy levels and feelings of well being and promotes overall systemic functioning and strengthens immune system Fatigue Fighter is a 100% natural safe and ...
You can then monitor any items you like.Check your inbox to activate the alerts.
No statements on this page have been approved by the FDA. Contact a doctor and get written permission
before beginning a new diet or using any supplement.
Prices, labels, and product availabilities change frequently. We make no guarantee on the accuracy of any of the listings on this site.


text:
The LX-50 is a gas-fired modular boiler that provides on-demand steam capability.
This enables the boiler to be turned on or off as needed to efficiently manage changing load conditions, saving an average of 20% annually on energy costs over other boiler options.
Polyglass U.S.A., Inc. has been manufacturing premium roofing products in North America for 25 years. Learn about our CURE Technology and ADESO Technology, innovations that have transformed the roofing industry.
Utility Vehicle Alert! Don't Get Framed. Rust can eat right through most UTV frames, destroy your investment and disable your crews. But this simple step stops rust in its tracks.


text: Been coming here for a few years now, beginning to feel it's losing it edge though. Everything used to be spot on.... food, service, decor the lot. Just feel now it's gradually going downhill, don't get me wrong by all means try it, still value for money it's just losing its edge I'm afraid.


text:
A Rose Recipe: No Bake Extra Tart Key Lime Pie
The Florida Keys and Key Lime Pie
The Florida Keys and Key Lime Pie
There is no such thing as too much Key Lime juice!
Key Lime Pie
Graham Cracker Crust
1 can sweetened condensed milk
1/2 to 3/4 cup nellie and joe's key west key lime juice (as in start with 1/2 cup of juice, mix in well and taste test. If you are feeling more tart, try adding an extra 1/4 cup key lime juice)
1 16 oz container cool whip- room temperature
mix together wet ingrediants REALLY well then pour into crust and even out. set into freezer for 12 hours and serve.
When I serve it, I add a drizzle of chocolate syrup on top for a touch of sweet.
So we lived in the keys for 2 years with a key lime tree in the yard. This lead to a great deal of key lime recipes and learning how to freeze the key limes so they could last past the week that they ripened on the tree. Nellie and Joe's Key West Key Lime Juice is the closest you can find to real key limes. Hope you enjoy!
11/22/2010 - Update!
For a fun twist on this Florida favorite, I made individual servings. I used tin foil cupcake holders and made my own graham cracker crust with the recipe below. After I made the crust mix and put it the holders, I let cool and filled with the Key Lime Pie recipe from above and put in the freezer overnight. This made 36 cupcake sized little pies that were a smash hit at the office.
Graham Cracker Crust
1 box of graham crackers (Finely crush in a ziploc bag)
1/4 Cup of sugar mixed with the crushed graham crackers
1 1/2 Cube melted non salted butter
Mix together and spoon into the tin foil cupcakes for a thin layer of crust on the bottom. Press down. Bake at 350 degrees for 5 minutes and let cool
If you are making into a pie crust for larger appetites - mold into the pie pan and bake at 350 degrees for 8-10 minutes
More by this Author
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Sigmund Freud the creator of this theory believed that the only way to get people to do work was to threaten them with punishment if they didn't do their work.
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The policies of Chairman Mao Zedong were like a mountain range—full of high points and dangerous low points—that brought out the best and worst of the people.
Comments 2 comments
Hi Rosemueller, my favorite pie. Thanks for sharing this recipe.


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Monlam Tibetan-Eng Dictionary
Iron Rabbit
- August 30, 2016
( 926)
Tibetan-English dictionary curated by Venerable Lobsang Monlam, a Tibetan monk from Sera Monastery in India. It contains over 200,000 entries, and is completely open-source.
All code and data here for you to share and study:
Learn more about Monlam-la and find more apps here:
བོད་ 藏区 藏區 Zàngqū
All code and data here for you to share and study:
Learn more about Monlam-la and find more apps here:
བོད་ 藏区 藏區 Zàngqū
Prefer the old format I regret having updated the app. It was much easier to use before with the old format. I was able to see details of multiple dictionary entries without having to click on each one. That option seems to be lacking now. It is also significantly slower.
I would've given the previous version of this dictionary five stars, but now I can't get it to work in English at all. Whenever I enter an English word, I get what I think is an error message in Tibetan... This is a Tibetan-English dictionary, isn't it? Is there still a way to search in English??? SOS
Now not working on Moto G4 plus with the latest update I am not able to use Monlam dictionary after the recent update. Earlier I had the same problem which was rectified by an update now the new update had created the same problem. Please rectify it soon. Thanks
got updated to 1.1 and now half the time it doesn't work, the screen above the search bar remains blank even after I type in it. not clear what the difference is the times I open it and it does work.. not happu
Great app and dictionary but crashes and stops working all the time. I have to reinstall almost daily. Motor Z Force Droid, Nougat 7.0. Had the same problem on my Droid Turbo with Lollipop.
It's good now! Thank you!
What's New
- BUG FIX: Database install now working
- fixed for the image editor screen, including better support for landscape
- dictionary updated from the latest dictionary by Geshe Lobsang Monlam
- added new camera option for image editing mode
- now using new Google Noto Tibetan font
- easy export of definitions to other apps in text or customizeable image!
- built-in Tibetan "app store" listing
- provides Tibetan word suggestions with Zom (https://zom.im)
This Application used for language translator,voice translations any language.


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in The Biology Files
Name the Bug #5
6 comments:
The tail's got a weird pattern that made me think "scaly-tailed flying squirrel", but it looks more like a colugo (Cynocephalidae). Cynocephalus volans?ReplyDelete
- Dartian26 November 2009 at 17:43
Mike, your first impression was surely correct; that's an anomalurid (a.k.a. a scaly-tailed squirrel). Colugos have shorter tails than that, and the peculiar "scaly" pattern at the tail's base is typical of anomalurids.ReplyDelete
As for which particular anomalurid species it is: since that's a pretty big animal by rodent standards, I'm going with Anomalurus peli, the largest species. (The presence of a patagium rules out Zenkerella, which is a smaller animal anyway.)
Ah whoops, I was going by pics of the pygmy one.ReplyDelete
That's the one all right. What are those odd struts coming out from around the elbows?
- Dartian26 November 2009 at 23:07
What are those odd struts coming out from around the elbows?ReplyDelete
Supporting rods of cartilage. That feature can be used to tell anomalurids apart from true flying squirrels; in the former, the cartilage rods emerge from the elbow joints, in the latter from the wrists.
I am confident (p<0.01) that this is NOT a protist.ReplyDelete
[room fills with awkward silence]
How the hell can you guys manage to identify random inconspicuous features of equally obscure animals??? *awed*
Microbial eukaryotes are so much easier to deal with...! =P
I was going to say that the "ouros" looked very anomalous to me, but Mike and Dartian were too quick for me!ReplyDelete
Gliding adaptations have evolved in mammals at least half a dozen times: how many of these forms have (had) extra "struts" to support the patagium analogous to the cartilaginous rods on this one? Do gliding possums have them? Are the fossils of Volaticotherium and the (??Miocene??) gliding dormouse good enough to tell whether they had anything like this?
Markup Key:
- bold = bold
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text: SF Crime Is So Bad Police Need Quad Bikes That Transform Into Jet SkisAlissa Walker7/27/15 1:30pmFiled to: quadbikesSFPDsan franciscopolicebaseballvehicles18221EditPromoteShare to KinjaToggle Conversation toolsGo to permalink Cops on Segways are so 1993 and no one takes them seriously. That's why San Francisco now has cops on quadskis, the ATV that turns into a jet ski that turns whoever's riding it into a kind of poor man's James Bond. And at least one of them is being used to patrol the San Francisco Bay during baseball games. Advertisement Fans at last weekend's Giants game were tickled by the presence of a quadski-straddling cop in McCovey Cove, the body of water that curls around AT&T Park. Those watching the ballgame from their boats snapped photos, and the amphibious vehicles were even shown on the game's television broadcast.The quadski is not some new vehicle designed just for keeping an eye on floating baseball fans—we wrote about it here at Gizmodo nine years ago, Jalopnik reviewed it last year, and it will be very familiar to fans of Top Gear. San Francisco has what looks like the Quadski XL, which can go 45 mph on both land and sea, and now retails for about $50,000. Advertisement But don't worry, SFPD did not spend public funds on this, according to SFist: "The vehicle was a gift from Salesforce.com CEO Marc Benioff." He gave three to the city.The quadski has already made waves in the crime-fighting world, too: Dubai's police force has its own fleet of quadbikes (OF COURSE). But beyond the flash-factor, is something like this really necessary for SFPD? Like how many times has a suspected criminal gave chase on a motorcycle through city streets then ditched the bike and leapt into a boat—except for that one time on Baywatch? Advertisement Sponsored Although baseball does brings out the crazy in people and maybe, just maybe, a cop would need to act so quickly to save a life he wouldn't have time to switch vehicles. Just the other day a guy jumped off the stadium concourse into the water to catch a home run ball. No one was hurt, but the quadski might have dramatically rescued him, towing him safely from the crime-ridden waters of McCovey Cove.[SF Gate, SFist] Advertisement Follow the author at @awalkerinLAReply182 repliesLeave a reply


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Book of the Month
I Let You Go by Clare Mackintosh
On a rainy afternoon, a mother's life is shattered as her son slips from her grip and runs into the street... I Let You Go follows Jenna Gray as she moves to a ramshackle cottage on the remote Welsh coast, trying to escape the memory of the car accident that plays again and again in her mind and desperate to heal from the loss of her child and the rest of her painful past. At the same time, the novel tracks the pair of Bristol police investigators trying to get to the bottom of this hit-and-run. As they chase down one hopeless lead after another, they find themselves as drawn to each other as they are to the frustrating, twist-filled case before them. I let You Go is one of The New York Times Book Review' s 10 Best Crime Novels of 2016.
The Woonsocket Harris Public Library Book Club will discuss I Let You Go on Wednesday, February 15, 2017 at 7 p.m.


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tag: tanya tate
9 Hottest Cat Women
Sure Halle Berry was hotter than the sun as cat women but these ladies set the bar a whole lot higher.
0 7 16
10 Jan, 06:43 PMJimmyHottass
Hot Pornstars in Bikinis
Damn it! National Bikini Day snuck up on me again! Here are some ultra hot porn stars in bikinis. #NationalBikiniDay
0 1 3
5 Jul, 04:37 PMJimmyHottass


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Waiting Tables
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Step-By-Step Fast Methods For Hip HopThere are special new era caps designed for the players. Sure, it will talk about what exactly is happening, however it doesn't cause the violence. Instead he
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Hotfrog Singapore provides information regarding Readylight in Singapore. Readylight is located at Kallang Place 04-00 Lim Kim Hai Building, Singapore 339177 and provides Battery services. Contact them on 6490 5049 or by visiting them on their website http://www.readylight.com.sg.
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Drug Profile
DE 096Alternative Names: DE-096
Latest Information Update: 25 Mar 2009
Price : $50
At a glance
- Originator Santen Pharmaceutical
- Class Small molecules
- Mechanism of Action Tumour necrosis factor inhibitors
Orphan Drug Status
Orphan designation is assigned by a regulatory body to encourage companies to develop drugs for rare diseases.
On Fast track
Fast track status is assigned by the US FDA so therapies with the potential to address unmet needs can move faster through development.
Highest Development Phases
- Discontinued Diabetic macular oedema; Rheumatoid arthritis
Most Recent Events
- 10 May 2005 Phase-II clinical trials in Rheumatoid arthritis in Japan (PO)
- 10 May 2005 Phase-II clinical trials in Diabetic macular oedema in Japan (PO)
- 31 Dec 2003 Phase-I clinical trials in Rheumatoid arthritis in Japan (PO)


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is back-ordered. We will ship it separately in 10 to 15 days.
Way Huge presents the Swollen Pickle fuzz pedal, a bright green stompbox that's full of big-sounding fuzz tone and juicy low end. The Swollen Pickle includes a Sustain control that takes you from a restrained crunch all the way to massive, stage-shaking tones, while a Filter knob makes it simple to dial in an array of awesome fuzz tones. Naturally, Way Huge didn't stop there! They also included Scoop and Crunch controls to adjust the midrange and compression characteristics, respectively. You can even access more controls inside the Swollen Pickle pedal!
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GOP will have hands full with pitch to minority voters
PHOENIX — The Republican party's plan to attract minority voters isn't going to be effective, in the opinion of a Valley political analyst.
KTAR political analyst Mike O'Neil said the $10 million outreach campaign is a drop in the bucket and likely won't work because the party remains fractured on immigration reform.
O'Neil said some party members are hostile to the issue. Mitt Romney took less than 30 percent of the Hispanic vote in November's presidential election.
"This feels like a futile effort until they decide on a policy level what they want to do. This won't be overcome with a six-month public relations campaign because their problems run far, far deeper."
O'Neil said it could take decades for the GOP to build trust with minority voters, if ever.
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Chapter 2 – BIOCHEMISTRY 2-3 "Carbon Compounds" A.The Chemistry of Carbon 1. Molecules that contain carbon (and hydrogen) are called ORGANIC COMPOUNDS 2. Each carbon atom has 4 valence electrons -- allows carbon atom to form 4 bonds with other atoms -- can form long carbon chains and rings
3. Carbon can form very large, complex molecules called POLYMERS a. A polymer is made from joining 1000's of smaller molecules (MONOMERS) in a long chain b. The process of joining monomers together to form polymers is called POLYMERIZATION
4.The 4 main type of ORGANIC COMPOUNDS found in living things are: 1) CARBOHYDRATES 2) LIPIDS 3) NUCLEIC ACIDS 4) PROTEINS
B.The Organic Compounds 1. CARBOHYDRATES a. Made of carbon, hydrogen, and oxygen in a 1:2:1 ratio -- ex. C 6 H 12 O 6 (glucose) C 15 H 30 O 15 (a sugar) C 10 H 20 O 8 (a lipid) b. Living things use carbohydrates for: 1) main source of energy 2) to make up certain cell parts CARBS
c. 2 main types of carbs: 1) sugars 2) starches d. SUGARS end in "ose" 1) Simple sugars -- called MONOSACCHARIDES -- one sugar molecule -- ex. Glucose, fructose, galactose 2) If join 2 simple sugars together you form a 2 sugar molecule DISACCHARIDE -- ex. Sucrose, maltose, lactose
3) If keep on joining simple sugars you form a many sugar molecule POLYSACCARIDE (a.k.a. STARCH) e.STARCH 1) A polysaccharide a long chain of sugars 2) ex. Pasta, rice, breads CARBS
3) animals store excess sugar as a polysaccharide called GLYCOGEN ("animal starch") in their LIVER 4) Plants store excess sugar as starch 5) Another important polysaccharide to plants is CELLULOSE makes up the CELL WALL in PLANT CELLS
2.LIPIDS a. Also made of C, H, and O (but not in 1:2:1 ratio) -- C 6 H 12 O 5 b. 3 main types: 1) FATS2) OILS3) WAXES c. Uses: 1) energy (2x as much as carbs) 2) make up cell membranes 3) waterproof coverings LIPS
d. Made up of 3 FATTY ACID MOLECULES attached to 1 GLYCEROL MOLECULE Glycerol Fatty acids LIPS FAT
e. SATURATED FAT – solid at room temp -- all carbon to carbon bonds are single in the fatty acid -- contain the maximum number of hydrogen atoms (saturated) LIPS
f.UNSATURATED FAT – liquid at room temperature -- contains at least on double or triple bond between 2 carbon atoms in a fatty acid -- does not contain the maximum number of hydrogen atoms Saturated fatty acid Unsaturated fatty acid Unsaturated Fat LIPS
-- if contains more than one double or triple bond –> called a POLYUNSATURATED FAT
3.NUCLEIC ACIDS a. Contains C, H, O, and N, and P (Nitrogen) (Phosphorus) b. 2 main types: DNA and RNA (deoxyribonucleic acid) (ribonucleic acid) c. Made of a long chain of NUCLEOTIDES made of:for DNA for RNA a. 5 – carbon sugar deoxyribose ribose b. A phosphate group c. A nitrogen base guanine (G) G (1 of 4 types) cytosine (C) C adenine (A) A thymine (T) uracil (U) NUCS
DNA double-stranded RNA single-stranded d. Uses Nucleic Acids store and transmit genetic information
4.PROTEINS a. Made of C, H, O, and Nitrogen, and some have Sulfur b. Used by organisms for GROWTH and REPAIR c. Made up of a long chain of AMINO ACIDS STRUCTURE OF AN AMINO ACID -- all amino acids have an AMINO GROUP and a CARBOXYL GROUP -- amino acids differ from each other in their R SIDE CHAIN PROS
d. There are 20 different types of amino acids
e.If join 2 amino acids together forms a DIPEPTIDE -- amino acids are held together by a PEPTIDE BOND f.If keep on adding amino acids to a dipeptide forms a POLYPEPTIDE PROS
g.A protein is made of 1 or more POLYPEPTIDE CHAINS h. Proteins differ from each other in their order of amino acids -- most proteins are 100's of amino acids long -- a protein of 100 amino acids made with the 20 different known amino acids can have 20 100 different arrangements (1.268 x 10 130 ) there is GREAT VARIETY in proteins PROS
i.Proteins also differ from each other in their SHAPE PProteins bend into different shapes based on the order of their amino acids PROTEIN SHAPES h.The instructions for building proteins in a cell is contained in DNA PROS
j.MAJOR TYPES OF PROTEINS: 1. ENZYMES – control chemical reactions in living things 2. the major BUILDING MATERIAL of cells 3. HORMONES – chemical messengers 4. ANTIBODIES – made by white blood cells to fight disease PROS
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text:
Roger Leroy Miller, David Vanhoose
Money, Banking and Financial Markets
Книгу можно купить в интернет-магазинах:
· OZON.ru 20757р. [Проверить наличие]
ISBN: 0324159935Издательство: South-Western Educational Publishing
This text strives to bring money and banking up-to-date by providing complete, integrated coverage of topics that are important to the twenty-first century world of money and banking. While covering the myriad topics appropriate for a money and banking course, the book is the first in the field to fully integrate coverage of international financial markets and the global economy from the outset. It also gives considerable attention to the ways in which new technologies are affecting the practice of banking, the nature of money, and the tasks of policymakers, and is the first and only text on the market to offer a fully-integrated program of accompanying online resources and multimedia tools that enhance a reader's study of money and banking.
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Holiday Cottage in Limassol with studio sleeps 3
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Description from the owner
Description from the owner
Bedrooms: 2/
Bathrooms: 2/
Sleeps: 6/
Type: Cottage
Book this 2 bedroom, 2 bathroom cottage in Limassol today! A total of 6 people can sleep here comfortably.
Guests can enjoy a outdoor grill, air conditioning, and parking space among other amenities offered by this rental.
No travelers have shared a review of this property yet.
Costs vary, with the average weekly rate as low as $568.00, depending on travel dates.
The owner responds to 75% of inquiries and last updated the property's calendar 2 years ago, so this rental may not be available for your requested dates, but please inquire to confirm.
Proximity to TripAdvisor's Top Limassol Attractions
Proximity to TripAdvisor's Top Limassol Attractions
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The author is a Forbes contributor. The opinions expressed are those of the writer.
The fall collections at Marc Jabobs and Christian Louboutin don't seem to have much to do with software. But with thousands of different items on line, often different from one region to another, the big business of fashion needs to be more automated than you might think. That's why both use platforms from a Silicon Valley startup, Centric Software, alongside other brands like Tommy Hilfiger and Nike. It's a specialty business that Centric carved out starting in 2005, and it's now raised $24 million to hit the hot market for retail: China.
China's where the growth is in fashion, especially in private label brands, Centric believes--starting with 30,000 private label brands sold in the big retailers. Private labels are twice as lucrative to a retailer than selling clothes by someone else, so everyone from retail chains to suppliers are getting into the game. That's why Fung Capital's co-led Centric's Series D round alongside Silver Lake Waterman and with existing partners Oak Investment Partners and Masthead Partners--as the investment arm of $20 billion (revenue) supplier and retailer Limited, Fung Capital invests in B2B companies that can help with its contracts with other retailers and across its own 4,000 stores.
"China's becoming a product brand and retail nation," says Centric CEO Chris Groves, where much of fashion's future will lie. "That's pretty exciting for our industry," he says, "Even as it goes through such pressure."
Centric makes its money by offering retailers and brands a centralized software system to handle their planning and buying, from the design process to scheduling samples and then managing an order. The company had tried to build a horizontal collaboration platform for all types of businesses, but saw a brighter future in refocusing purely on the retail and fashion market. "Other industries like automotive had these tools, but the consumer product industry hadn't really adopted it," says Groves. "If you were a large company like , you might deploy over a decade on a generic platform, then $20 million or more customizing the solutions."
The big competition in the space, called product lifecycle management, range from giants like and to PLM Software and French leader Dassault Systemes. Within fashion, it's got competition like Lectra, a public company that gets a little less than half of its business from fashion and has a market cap of about $225 million.
That's not huge, but Groves is hopeful that the boom of the Chinese fashion and apparel market will grow the sector significantly in the next several years. Centric entered the European market after its Series B round six years ago, and Groves says the platform becomes profitable in each geography after two years.Clients there include Tommy Hilfiger Europe and Calvin Klein Europe, which have 1,000 employees and suppliers on the software.
Centric claims that it can set everything up in between 8 and 16 weeks, versus one to two years for competitors. There's still a key services component as Centric meets with clients and presents three or four versions of its customized software before the client starts. Centric also offers 8 mobile apps right now to customers, with more in the works.
It's not the sexiest business, but it's one that Groves says typically improves product margins by about 2% and employee productivity by between 25% and 50%. With billions pouring into Chinese companies that can scale up brands quickly for the growing consumer market in the country, that money adds up fast.
Fung Capital's been gunning for the revenues from improving that production process for years. Now it's got to help Centric get a slice.
Follow Alex on Forbes, Twitter and Facebook for more coverage of startups, enterprise software and venture capital.


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History of the Contest:
In 2012 the Mine Warfare Association leadership approached the U.S. Naval Institute with the idea of sponsoring an essay contest exploring the subject of mine warfare. The Institute was immediately interested in supporting such a program, and agreed to an inaugural essay contest in 2013, with the objective of making it an annual event going forward.
The Challenge:
Address the strategic, operational, and tactical demands for 21st-Century Navy mine warfare-mine countermeasures, mining-technologies, systems and platforms, explosive ordnance disposal. Examine the promise of autonomous and unmanned vehicles. Consider the difficulties of delivering capable and affordable solutions to the fleet.
Prior Publication: We will assume that your essay has not been previously published (online or in print) or being considered for publication elsewhere, unless otherwise notified by you. All previously published essays are ineligible.
Submission Guidelines:
Selection Process: A joint panel composed of experts from the Mine Warfare Association and the Proceedings editorial staff shall judge essays and choose winners. All essays will be judged in the blind -- i.e., the Proceedings staff members and Mine Warfare Association judges will not know the authors of the essays.
Memberships: All prize winners receive one-year memberships in the U.S. Naval Institute.
About Naval Institute Essay Contests
Essay contests have been central to the work of the Naval Institute for more than 130 years. They directly fulfill the Institute's educational mission by encouraging writing on issues of concern to the Sea Services. They provide thought-provoking articles that spur ongoing discussion of these same issues, not only in Naval Institute media, print and digital, but also in other leading defense and national security forums.