text:
Antigen presentation
Antigen presentation describes a vital immune process. Because T cells only recognise antigens displayed on the cell surfaces, an antigen-presenting complex is needed for detecting infectious cells. After infection with viruses or bacteria, the cells present endogenous peptide fragments derived from the pathogen by major histocompatibility complex (MHC) molecules on the cell surface. There are two types of MHC, depending on the source of the antigens: MHC class I molecules (MHC-I) binds peptides from the cytosol, while peptides generated in vesicles are bound to MHC class II (MHC-II).[1] T cells can recognise among ten to hundreds of thousands peptides because each MHC molecule can bind a different range of peptides.[2][3]
Intracellular antigens: Class I[edit]
Cytotoxic T cells regularly patrol body cells to maintain the organism healthy. Whenever they encounter signs of disease, caused for example by the presence of viruses or intracellular bacteria, they initiate processes to destroy the potentially harmful cell.[1] To effect recognition, all nucleated cells in the body (along with platelets) display class I major histocompatibility complex (MHC-I molecules). Antigens generated endogenously within the cells (DAMPs) are bounded to MHC-I molecules and presented on the cell surface. This antigen presentation pathway enables the immune system to detect transformed or infected cells displaying peptides from modified-self or foreign proteins.[4][5]
In the presentation process, these proteins are mainly degraded into small peptides by cytosolic proteases in the proteasome, but there are also other cytoplasmic proteolytic pathways. Then, the transporter associated with antigen processing (TAP) translocates the cytosolic peptides into the ER lumen in an ATP-dependent transport mechanism. There are several ER chaperones involved in MHC-I assembly, as calnexin, clareticulin and tapasin. Because of the association between TAP and MHC-I, the peptides are loaded to MHC-I molecules. After releasing from tapasin, peptide-MHC-I complexes (pMHC-I) exit the ER and are transported to the cell surface by exocytic vesicles.[6]
Naïve anti-viral CD8+ T cells (TCD8+) cannot directly eliminate transformed or infected cells. They have to be activated by the pMHC-I complexes of antigen-presenting cells (APCs) . Antigen can be presented directly or indirectly (cross presentation) from virus-infected and non-infected cells.[7] After the interaction between pMHC-I and TLR, in presence of costimulatory signals and/or cytokines,T cells are activated and kill the target cells (infected or damaged cells) by inducing cytotoxicity.
Cross-presentation is a special case in which MHC-I molecules are able to present extracellular antigens, usually displayed by MHC-II molecules. This ability appears in several APCs, mainly dendritic cells, that stimulate CD8+ T cells. This process is essential when APCs are not directly infected, triggering antiviral and antitumour immune responses.[5]
Extracellular antigens: Class II[edit]
Antigens from the extracellular space (PAMPs) and also endogenous ones,[8] are enclosed into vesicles and presented on the cell surface by MHC-II molecules to CD4+ T cells. Only professional APCs have this class of MHC molecules, such as dendritic cells, B cells or macrophages, so expression of MHC-II molecules is more restricted than MHC-I.
APCs usually internalize exogenous antigens by endocytosis, but also by pinocytosis, macroautophagy, endosomal microautophagy or chaperone-mediated autophagy.[8] In the first case, after internalisation, the antigens are enclosed in vesicles called endosomes. There are three compartements involved in this antigen presentation pathway: early endosomes, late endosomes or endolysosomes and lysosomes, where antigens are hydrolized by lysosome-associated enzymes (acid-dependent hydrolases, glycosidases, proteases, lipases...). This process is favored by the gradually reduction of the pH. The main protease is cathepsin and the result is the degradation of the antigens into oligopeptides.
MHC-II molecules are transported from the ER to the endosomes by the protein Invariant chain (Ii, CD74). A non classical MHC-II molecule (HLA-DM) catalyses the exchange of part of the CD74 (CLIP) with the peptide antigen. Peptide-MHC-II complexes (pMHC-II) are transported to the plasma membrane and the processed antigen is presented to CD4+ T cells in the lymph nodes.[6]
DCs undergo a process of maturation while migrating, via chemotactic signals, to lymphoid tissues, in which they lose the phagocytic capacity and develop an increased ability to communicate with T-cells by antigen-presentation.[9] As well as in CD8+ T cells, APCs need pMHC-II and aditional costimulatory signals to activate T helper cells.
Intact antigens: Presentation to B cells[edit]
B-cell receptors bind to intact, undigested antigens, rather than to proteins which have been digested and presented by MHC molecules. Small antigens sometimes encounter B cells after diffusing on their own to lymph nodes, but larger pieces of intact antigen appear to be presented to B cells by follicular dendritic cells and macrophages. It seems that these macrophages express comparatively lower levels of lysosomal enzymes and thus are less likely to digest the antigen they have captured before presenting it.[10][11]
See also[edit]
- ^ a b Charles A Janeway, Jr; Travers, Paul; Walport, Mark; Shlomchik, Mark J. (2001-01-01). "Antigen Presentation to T Lymphocytes".
- ^ Purcell, Anthony W; Croft, Nathan P; Tscharke, David C. "Immunology by numbers: quantitation of antigen presentation completes the quantitative milieu of systems immunology!". Current Opinion in Immunology. 40: 88–95. doi:10.1016/j.coi.2016.03.007.
- ^ Charles A Janeway, Jr; Travers, Paul; Walport, Mark; Shlomchik, Mark J. (2001-01-01). "The major histocompatibility complex and its functions".
- ^ Hewitt, Eric W. (2003-10-01). "The MHC class I antigen presentation pathway: strategies for viral immune evasion". Immunology. 110 (2): 163–169. doi:10.1046/j.1365-2567.2003.01738.x. ISSN 1365-2567. PMC 1783040. PMID 14511229.
- ^ a b Joffre, Olivier P.; Segura, Elodie; Savina, Ariel; Amigorena, Sebastian. "Cross-presentation by dendritic cells". Nature Reviews Immunology. 12 (8): 557–569. doi:10.1038/nri3254.
- ^ a b Bhattacharya, J. K. Sinha & S. A Text Book of Immunology. Academic Publishers. ISBN 9788189781095.
- ^ Sei, Janet J.; Haskett, Scott; Kaminsky, Lauren W.; Lin, Eugene; Truckenmiller, Mary E.; Bellone, Clifford J.; Buller, R. Mark; Norbury, Christopher C. (2015-06-24). "Peptide-MHC-I from Endogenous Antigen Outnumber Those from Exogenous Antigen, Irrespective of APC Phenotype or Activation". PLOS Pathogens. 11 (6): e1004941. doi:10.1371/journal.ppat.1004941. ISSN 1553-7374. PMC 4479883. PMID 26107264.
- ^ a b "The melting pot of the MHC II peptidome". www.sciencedirect.com. Retrieved 2017-01-04.
- ^ Flores-Romo, Leopoldo (2017-01-04). "In vivo maturation and migration of dendritic cells". Immunology. 102 (3): 255–262. doi:10.1046/j.1365-2567.2001.01204.x. ISSN 0019-2805. PMC 1783189. PMID 11298823.
- ^ Batista, Facundo D.; Harwood, Naomi E. (January 2009). "The who, how and where of antigen presentation to B cells". Nature Reviews Immunology. Macmillan Publishers Limited. 9: 15–27. doi:10.1038/nri2454. Retrieved 25 May 2016.
- ^ Harwood, Naomi E; Batista, Facundo D (Dec 17, 2010). "Antigen presentation to B cells". F1000 Biol Reports. Faculty of 1000 Ltd. 2: 87. doi:10.3410/B2-87. PMC 3026618. PMID 21283653.
External links[edit]
- ImmPort - Gene summaries, ontologies, pathways, protein/protein interactions and more for genes involved in antigen processing and presentation
- antigen presentation at the US National Library of Medicine Medical Subject Headings (MeSH)


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Two Heads are Better Than One
By (author) Hillary Homzie
Illustrated by Matthew R. Phillips
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Book DescriptionDouble Trouble! Barton and Nancy Jamison are just regular kids. That is until alien clones land in their hometown of Pine Bluff. Now there are two Barts and two Nancys! BUT (and this is a really big butt) the alien clones, Beta and Gamma, have a totally wacky take on Earth life. Whenever they're around, something always gets messed up.
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Book DetailsISBN: 9780689823428
(190mm x 127mm x 6mm)
Pages: 80
Imprint: Aladdin Paperbacks
Publisher: Aladdin Paperbacks
Publish Date: 1-Nov-2002
Country of Publication: United States
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Books By Author Hillary Homzie
Queen of Likes, Paperback / softback (May 2016)
A tween social media queen is forced to give up her phone and learn that there's more to life than likes.
Things Are Gonna Get Ugly, Paperback (August 2009)
Upon her arrival in California, Ernestine Smith reinvents herself as Taffeta and becomes the leader of the most popular clique at La Cambria Middle School. That is, until she's caught cheating and her teacher gives her the option of a fresh start--which isn't what Taffeta expects.
Who Let the Dogs Out?, Paperback (January 2003)
Twins Barton and Nancy try to use their alien clones to buy tickets for a rock concert, but their plan leads to chaos.
Hot List, Paperback / softback» View all books by Hillary Homzie
Is popularity hot or not? Homzie's "The Hot List" features quintessential tween conflicts and themes of friendship, crushes, and popularity.
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Author Biography - Hillary Homzie
Hillary Homzie has written several books for tweens, including Things Are Going to Get Ugly, The Hot List, and Queen of Likes for Aladdin M!X. She lives in Napa, California with her family.
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Des Moines has a population of 198,682 and is located in Polk county.
Business Writing schools in Des Moines charged students an average tuition of $13,917.00 if they were Iowa residents, and $13,917.00 if they were non-residents, during the 2009 - 2010 school year.
Books and supplies for business writing schools in Des Moines cost an average of $1,006.00. Students who live on campus while attending a business writing school in Des Moines, can expect to pay an average of $6,184.00 for room and board. Students who live at home can expect average costs to be $3,335.00. Students have a choice of one business writing college in Des Moines to attend. Business Writing programs in Des Moines reportedly graduated 14 students in the 2008 - 2009 school year.
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Initially grown from a defensive fort in Hadrian's Wall, Newcastle has become a world leading travel destination and is now one of the most culturally influential cities in the UK. Recognised for its contrasting rich history and modern attitudes, there's always something to see and do in the city, and car hire in Newcastle is well within reach. Hiring a car in Newcastle to experience the Geordie hospitality in its entirety - their warmth is unmatched to any other city in the UK. Whether you plan on visiting for its history and heritage or those interested in Newcastle for its famous nightlife - the people of Newcastle will be sure to make you feel extremely welcome.
Incredibly popular amongst those looking for a vast selection of entertainment attractions; Newcastle is the perfect long weekend break destination. With an array of lively restaurants and bars to stunning architecture and lush landscapes; Newcastle really has it all.
Consider hiring a car in Newcastle and visit its long list of must-see attractions; you only have to drive around to experience the incredible beauty of this city. Don't miss the BALTIC Centre for Contemporary Art, with value for money being at the core of any trip, the free entry to this inspiring gallery means you're getting more than your money's worth. You can''t visit the north without seeing the Angel of the North - rent a car in Newcastle and stand at the feet of this incredible piece of public art and be overwhelmed by the sheer craftsmanship of this piece. If you're looking for more of a learning experience, then why not visit some of the marvellous museums Newcastle has to offer? Whether you're into science, history or photography - there's an extensive variety of educational experiences at your fingertips.
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Dancing Revelations
Alvin Ailey's Embodiment of African American Culture
By (author) Thomas F. DeFrantz
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Dancing Revelations by Thomas F. DeFrantz
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Book DescriptionIn the early 1960s, the Alvin Ailey American Dance Theater was a small, multi-racial company of dancers that performed the works of its founding choreographer and other emerging artists. By the late 1960s, the company had become a well-known African American artistic group closely tied to the Civil Rights struggle. In Dancing Revelations, Thomas DeFrantz chronicles the troupe's journey from a small modern dance company to one of the premier institutions of African American culture. He not only charts this rise to national and international renown, but also contextualizes this progress within the civil rights, women's rights, and gay rights struggles of the late 20th century. DeFrantz examines the most celebrated Ailey dances, including Revelations, drawing on video recordings of Ailey's dances, published interviews, oral histories, and his own interviews with former Ailey company dancers. Through vivid descriptions and beautiful illustrations, DeFrantz reveals the relationship between Ailey's works and African American culture as a whole. He illuminates the dual achievement of Ailey as an artist and as an arts activist committed to developing an African American presence in dance. He also addresses concerns about how dance performance is documented, including issues around spectatorship and the display of sexuality, the relationship of Ailey's dances to civil rights activism, and the establishment and maintenance of a successful, large-scale Black Arts institution. Throughout Dancing Revelations, DeFrantz illustrates how Ailey combined elements of African dance with motifs adapted from blues, jazz, and Broadway to choreograph his dances. By re-interpreting these tropes of black culture in his original and well-received dances, DeFrantz argues that Ailey played a significant role in defining the African American cultural canon in the twentieth century. As the first book to examine the cultural sources and cultural impact of Ailey's work, Dancing Revelations is an important contribution to modern dance history and criticism as well as African-American studies.
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Book DetailsISBN: 9780195301717
(235mm x 153mm x 18mm)
Pages: 320
Imprint: Oxford University Press Inc
Publisher: Oxford University Press Inc
Publish Date: 2-Mar-2006
Country of Publication: United States
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Books By Author Thomas F. DeFrantz
Dance, Hardback (March 2016)
A landmark examination of the art and artists inspired by American dance from 1830 to 1960
Black Performance Theory, Paperback (May 2014)
Black performance theory is a rich interdisciplinary area of study and critical method. In this collection of new essays, some of its pioneering thinkers demonstrate the breadth and depth, innovation, and critical value of black performance theory.
Dancing Many Drums, Paperback (March 2002)» View all books by Thomas F. DeFrantz
This volume explores the influence of African American music on world culture. It brings together issues of race, gender, politics, history and dance, includes discussions of dance instruction songs, the blues aesthetic, and Katherine Dunham's controversial ballet about lynching, "Southland".
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Author Biography - Thomas F. DeFrantz
Thomas DeFrantz earned degrees from Yale, the City University of New York, and the Performance Studies Department of New York University. He organized the dance history program at the Ailey School, and is editor of Dancing Many Drums: Excavations in African American Dance. His writings have appeared in the Encyclopedia of African American Culture and History, and the Village Voice. Also a performer and choreographer, DeFrantz has taught at NYU and Stanford University. He is currently Associate Professor of Theater Arts at the Massachusetts Institute of Technology.
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text: Mike Ashley yesterday provided further evidence that it is the poorest households that are being hit hardest by the squeeze on incomes because they spend a higher proportion on food and fuel. The owner of Sports Direct, whose shares plunged to a new low yesterday, said management was in the bunker because sales at the lower end of the market were really suffering. Not that it should be much of a worry for Mr Ashley who took out £1 billion when the company floated last year. For him, cutbacks could mean "10 crates of Bolly rather than 12".


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Bristol Museum & Art Gallery
Queens Road, Bristol, BS8 1RL
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Join us on a family friendly curator-led guided tour of the Jurassic fossil treasures cared for behind the scenes in the geology store.
Bristol was very different 150 million years ago, covered in warm seas that were teeming with ancient life while the dinosaurs roamed the land. You certainly wouldn't see these animals alive today!
Discover the ancient marine reptiles that swam in the Jurassic sea like the amazing ichthyosaurs, and fantastic long necked plesiosaurs, on the lookout for their next meal of fish, ammonites or squid.
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Flip-flop Party Invitation
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- Cut 2 pieces cardstock in 2 shades of blue, in progressively smaller sizes, as shown. Attach.
- On light aqua border, write details of party with blue pen.
- Stamp the words, "POOL PARTY" on light aqua paper. Cut out individual letters into squares.
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- Attach invitation to flip-flop and add a festive bow.
- Trace flip-flop sole on paper. Cut out pattern and cut notches on sides for strap and hole for toe thong.
- Use pattern as a guide for cutting paper out for the sky, sea and sand. (To trace, enlarge to match size of your flip-flop.) Assemble.
- Lightly pencil in "BEACH PARTY". Stipple along lines with fine black marker.
- Write party information on narrow strips of lavender paper. Cut into segments and attach. Glue paper design to flip-flop.
- Attach stickers as desired.
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Wonderful Ethiopians of the Ancient Cushite Empire
By (author) Drusilla Dunjee Houston
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Wonderful Ethiopians of the Ancient Cushite Empire by Drusilla Dunjee Houston
Book DescriptionOur story will deal with the ancient Cushite empire of Ethiopians, that covered three continents and held unbroken sway for three thousand years. We will visit old Ethiopia, where as Herodotus said, "the gods delighted to banquet with the pious inhabitants." We will study the land and the ancient race. The "Old Race," will next win our attention, that Petrie found in Egypt of distinct and unique culture, who were the people of the earlier and superior civilization of the first dynasties. Down through this prehistoric vista we see "Happy Araby" with her brilliant primitive culture and her unrivalled literature of later days. On the screen flashes the rich and surpassing culture of old Chaldea, which belonged to the ancient Cushite empire of Ethiopians. Next comes veiled and mysterious India, the scene of charming story and magic fable, with her subtle mysticism and philosophy. Tarrying a while with the conquest and life of the ancient Medes and Persians, the trail runs far afield into the dominions of Western Europe and the striking questions array themselves demanding to be answered. Who were the Celts? Who were the Teutons? and what was the origin of the so-called Aryan race? The author was as much astounded as will be the reader, as to what this study reveals. It leaves us wondering if there is any Aryan race.
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Book DetailsISBN: 9781595478528
(229mm x 152mm x 9mm)
Imprint: NuVision Publications
Publisher: NuVision Publications
Publish Date: 30-Sep-2007
Country of Publication: United States
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We experimentally demonstrate the performance of a 10 Gb/s subcarrier multiplexed (SCM) wavelength-division multiplexed (WDM) passive optical network (PON) using 2.5 Gbaud 16-QAM transmission signals. Digital signal processing (DSP) and square-root raised cosine (SRRC) pulse shaping enable both the uplink and downlink channels to achieve net spectral… (More)
— We demonstrate an overlapped-SCM WDM PON using a burst-mode receiver capable of tracking instantaneous phase variations within the uplink. The receiver ensures proper alignment between the clock and up-converted data for efficient SCM down-conversion.
—Coherent optical interleave-division multiple-access (OIDMA) has been recently proposed for next generation passive optical network (NG-PON) systems. In this paper we present a performance evaluation and comparison of coherent OIDMA and coherent optical code-division multiple-access (OCDMA) PONs in terms of ONU launch power, PON reach, bit error rate… (More)
- Ziad A. El-Sahn
- 2012
—An innovative overlapped-subcarrier multiplexing (O-SCM) technique is proposed for single-feeder wavelength-division multiplexed (WDM) passive optical networks (PONs). Allowing a certain amount of spectral overlap between the uplink and the downlink maximizes the spectrum usage of bandwidth-limited reflective semiconductor optical amplifier (RSOA)-based… (More)
We experimentally investigate the performance of a low-complexity non-iterative phase noise induced inter-carrier interference (ICI) compensation algorithm in reduced-guard-interval dual-polarization coherent-optical orthogonal-frequency-division-multiplexing (RGI-DP-CO-OFDM) transport systems. This interpolation-based ICI compensator estimates the… (More)
—A queuing subsystem is proposed to the round robin receiver/transmitter (R 3 T) optical code-division multiple-access (OCDMA) protocol. The corresponding state diagram and its mathematical model are outlined. We prove that significant improvement in terms of system throughput and blocking probability can be achieved by only adding a single buffer at each… (More)
- Yousef M Abdelmalek, Ziad A El-Sahn, M H Hossam, Shalaby, El-Sayed Abdel-Moety El-Badawy
- 2007
A random access protocol that adopts stop-and-wait automatic repeat request ͑ARQ͒ is proposed for optical code-division multiple-access ͑CDMA͒ communication systems. A detailed state diagram and a mathematical model based on the equilibrium point analysis ͑EPA͒ technique are presented. Several performance measures are evaluated under different network… (More)
- Ziad A. El-Sahn, Julien Penon, Leslie A. Rusch
- 2006
— We simulate both the throughput and the delay of an experimental 7×622 Mbps SAC-OCDMA system. Our results reveal that the R 3 T protocol performs better than S-ALOHA CDMA protocol and provides a 4.5 dB improvement.
A new random access protocol for optical code division multiple access (CDMA) communication systems is proposed. Stop & wait automatic repeat request (ARQ) is implemented at the optical link layer. A detailed state diagram and a mathematical model based on the equilibrium point analysis (EPA) technique are presented. Several performance measures are… (More)
- ‹
- 1
- ›


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Hotfrog SouthAfrica provides information regarding Mark Pilgrim in Randburg Gauteng. Mark Pilgrim is located at 6 Nerina St, Randburg Gauteng and provides website services. Contact them by visiting them on their website http://www.markpilgrim.co.za.
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- Write a Review
Gig? Use it. Session? Use it. Cool microphone.
Audio-Technica's AT2005USB is an all-purpose microphone designed to take you from the stage to the studio and beyond. This rugged handheld microphone offers two outputs, USB output for digital recording, and an XLR output that connects with a sound system's conventional microphone input for use in live performance. The microphone plugs right into your computer's USB port, and functions seamlessly with your favorite recording software.
The AT2005USB also offers a quality analog-to-digital converter for excellent fidelity, and a headphone output with level control for monitoring. Its cardioid polar pattern reduces pickup of unwanted sounds from the sides and rear. The microphone is ideal for live performance, podcasting, home studio recording, field recording, and voiceover use.
- Handheld dynamic microphone with USB digital output and XLR analog output
- USB output connects to your computer for digital recording
- XLR output connects for use in live performance
- Suited for podcasting, recording, voiceover, and on-stage use
- Built-in headphone jack allows you to directly monitor from your microphone
- Adjust headphone volume from the bottom of the microphone
- AD convertor with 16 Bit, 44.1/48 kHz sampling rate
- Compatible with Windows and Mac
- Low-mass diaphragm provides excellent frequency response
- Cardioid polar pattern reduces pickup of unwanted sounds
- Tripod desk stand with folding legs for secure and easily portable tabletop use
- Threaded stand clamp
- Cables included
- Durable metal construction for long-lasting performance
- On/off switch functions for both USB and analog operation
USB and XLR have never been closer together. Order today for a truly multi-purpose microphone.
AT2005USB Cardioid Dynamic Handheld USB/XLR Microphone
- Element: dynamic
Polar pattern: cardioid
Frequency response: 50-15,000 Hz
Power requirements: usb power (5v dc)
Bit depth: 16 bit
Sample rate: 44.1 khz/48 kHz
Controls: on/off switch;
Headphone volume control
Weight: 266 g (9.4 oz)
Dimensions 183.6 mm (7.23") long,
51.0 mm (2.01") maximum body diameter
Output connector: USB-type/XLR-type
Headphone output power: 10 mw at 16 ohms
Headphone jack: 3.5 mm trs (stereo)
System requirements: Macintosh: Mac os x; usb 1.0 or 2.0; 64 mb ram (minimum)
Windows: XP/Vista/Windows 7; usb 1.0 or 2.0; 64 mb ram (minimum)
Accessories furnished stand clamp for 5/8"-27 threaded stands; tripod desk stand; 6.6' (2 m) mini usb cable, 9.8' (3 m) xlrf-type to xlrm-type cable
Audio-technica case style t7
Reviewed by 1 customer
- It's Solid It Works
- Nada
Best Uses
Comments about Audio-Technica AT2005USB Cardioid Dynamic Handheld USB/XLR Microphone:
I got this mostly for speech recognition.
But downloaded free software and now just leave it available on a little notebook for any song writing ideas. Can't lose for the price. I'm pleasantly shocked of the quality.
- Was this a gift?:
- No


text:
If you join SET from 1 January 2017, you can benefit from up to 14 months of membership for the price of 12. To make the most of your SET membership, pay by Direct Debit so you can spread the payments out throughout the year.
Subscription rates and payment options for the Society for Education and Training (SET) are listed below. SET's membership year runs from 1 April to 31 March.
SET also offers members joining after 1 October each year a discounted rate until 31 December. Please note that the discounted rates shown cannot be used in conjunction with the concessionary rates also offered by SET (see separate section below).
In order to make membership fees more manageable for you, and in response to member feedback, we have introduced monthly direct debits to spread out the cost of membership.
If you have set up a Direct Debit with SET, your subscription fees for 2017-2018 onwards will be collected automatically. There is no need to set up a new one each year - we will continue taking subscription payments unless you tell us that you wish to resign from membership. Direct Debit payments will be collected starting on or around 1 April 2017 and instalments will continue on or around the first of each month to 1 March 2018. Unless you tell us otherwise, you are committing again to the same declarations as the year before.
We will remind you that your subscription is due for renewal and keep you informed if your subscription payment changes. Please do contact us if there is a change to your bank details.
If your circumstances have changed and you are eligible to pay a concession rate then please let us know as soon as possible.
See further details on payment plans by direct debit.
Concessionary rates are available to members who have retired from the profession, are on a low income, are unemployed at the time of renewing their membership or are undertaking a full-time or part-time pre-service teaching qualification.
Concessionary band
Concessionary membership subscription fees
Full-time or part-time initial teacher training
Retired from the teaching or training profession
Unemployed or on maternity leave at the point of joining or renewing membership
If earnings are below the income tax threshold, £11,000 pa for 2016/17
Earnings above the income tax threshold, but less than £16,190
Fellows earning below the income tax threshold, £11,000 pa for 2016/17 (or Retired/Unemployed)
Fellows earning above the income tax threshold, but less than £16,190
To find out whether you are eligible for these rates please email firstname.lastname@example.com
We work hard to keep the membership fee as low as possible. However, with some core costs continuing to increase, such as postage and payment processing, we need to charge a small administrative fee, on some transactions.
SET does not benefit from this but it does enable us to continue to provide the widest range of relevant benefits to members.
Payment can be made by any of the following methods:
Payment method
Administration fee
Direct debit
Debit card
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Employer billing
Where an employer is able to support the cost of membership, SET anticipates that this will be through the full or part-reimbursement of professional expenses or a professional subscription loan scheme.
*All prices are inclusive of VAT


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political leaders
Jim Wallis 01-27-2011
Yesterday was the first day of the World Economic Forum in Davos, a little mountain village in Switzerland, where each January corporate CEOs, heads of state, and leaders of nonprofit organizations
Jim Wallis 01-13-2011
Many members of Congress and their staffers have had friends and loved ones call to check on their personal safety.
Jim Wallis 01-11-2011
Sheldon Good 12-02-2010
This Advent season, "waiting" has new meaning for hundreds of thousands of undocumented immigrant students.
Jim Wallis 08-25-2010
"Nazis don't have the right to put up a sign next to the Holocaust Museum in Washington," said former House Speaker Newt Gingrich.
Brian McLaren 07-16-2010
I often say that one of my favorite parts of being a pastor for 24 years was pronouncing the benediction each week at the end of gathered worship.
Ian Danley 05-17-2010
Allen Johnson 05-17-2010
In this month's Sojourners, Onleilove Alston takes a spiritually inflected look at coal country, where last month's EPA decision to ban much mountaintop removal min
Elizabeth Denlinger Reaves 05-05-2010
Watching a disaster unfold on the news is always heartbreaking, but when it occurs in your hometown and you are far away, it can be debilitating.
Celestin Musekura 04-15-2010
Sudan's impending presidential and parliamentary elections have degenerated into a chaotic mixture of fraud accusations, boycotts, political assassinations, intimidation, abuses of power by the rul
Rabbi Arthur Waskow 04-12-2010
Aaron Taylor 04-09-2010
I love the New Testament. I think it's fair to say that I live, eat, breathe, and drink the New Testament.
Allison Johnson 03-26-2010
Jim Wallis 02-17-2010
Sometimes things get so bad that you really don't know what to say or do. When that happens, it's a good time to fast and pray.
Jacqueline Klamer 02-09-2010
Law student Sebastien Doussous currently manages the database on a needs-assessment survey administered, just days following the Jan. 12 earthquake, by members of his church, L'...glise Communauté Evangélique d'Haïti (Evangelical Community Church of Haiti, L'ECEH).


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Sportsmen Classic 17FKTH
The Sportsmen Classic 17FKTH toy hauler travel trailer by KZ has 7'6" of cargo length space and a 60" x 70" rear ramp door for easy loading and unloading of your off-road toys.
In the cargo area you will find two flip-beds, one on either side of the trailer.
Along the front of the trailer there is a two burner gas hot plate, counter space, and a sink. To the left of the entrance is a refrigerator and TV.
Inside the front corner bathroom you will find a toilet and a shower. Next to the bathroom there is a nice size closet for added storage.Have a question about this floorplan?Contact Us
Sleeps 2 Length 17 ft 4 in Ext Width 7 ft 6 in Ext Height 8 ft 8 in Int Height 6 ft 3 in Hitch Weight 350 lbs Gross Weight 3500 lbs Dry Weight 2400 lbs Cargo Weight 1100 lbs Fresh Water Capacity 38 gals Grey Water Capacity 26 gals Black Water Capacity 5 gals Tire Size 14" Furnace BTU 16000 btu
Similar Toy Hauler Travel Trailer Floorplans
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*All calculated monthly payments are an estimate for qualified buyers only and do not constitute a commitment that financing or a specific interest rate or term is available. Financing terms may not be available in all Campers Inn locations. Campers Inn RV Sales is not responsible for any misprints, typos, or errors found in our website pages. Any price listed excludes sales tax, registration tags, and delivery fees. Manufacturer pictures, specifications, and features may be used in place of actual inventory in stock on our lot. Please contact us for availability as our inventory changes rapidly.


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back by popular demand:
Signature Massage Services
Three Massages or a Two-Hour Spa Package
- Save 50%
- 49 purchased
71% recommendedin LivingSocial customer ratings
Make a date with relaxation with this offer from Signature Massage Services. You'll leave your session feeling rejuvenated, restored, and refreshed:
• $127 ($255 value) for three 50-minute massages (Swedish or hot stone)
• $110 ($220 value) for a two-hour spa package
• Conveniently located on Northup Way in Bellevue
"Great service -- wonderful experience!" - LivingSocial Member
Why You'll Love It
For an utterly indulgent experience, Swedish and hot stone massage are perfect. With either modality, you'll be able to relax and let the rest of the world melt away for a while -- and you'll get to do so three times. The two-hour spa package is also a treat, and it includes a foot soak, Turkish body scrub, 50-minute Swedish massage, peppermint scalp massage, and moisturizing mask.
PAID VALUE EXPIRES ON February 22, 2022
PROMOTIONAL VALUE EXPIRES ON December 19, 2013


text:
Show all Arrivals
Terminal Map (PDF)
Find us on Google
this time is for security line-up wait time ONLY.
More Security Screening Information
Parking Information
With an updated terminal and the 2015 award for most improved Airport, we thought it was time to complete our make-over. The Saskatoon Airport Authority is now known as Skyxe (pronounced sky – ex- ee) and we are so excited to show off our new duds. With new colours, a new name and a changing atmosphere, our fresh brand is sure to bring a smile when you least expect it.
Say it with me now…sky…ex…ee. Skyxe. Good job! Sounds good, doesn't it? Our name is unique, but it is full of meaning. Let's break it down a bit.
It's all about the uplifting experience we'll deliver – from the moment you walk through our front doors to the minute your flight takes off.
Learn More
From renovations to changing our atmosphere, we're always doing something new and exciting at the Saskatoon Airport to make your experience with us and uplifting one!
Check it out
Please follow the link for 2016-2017 CAP Program and Application Guidelines.
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Attention A T users. To access the menus on this page please perform the following steps. 1. Please switch auto forms mode to off. 2. Hit enter to expand a main menu option (Health, Benefits, etc). 3. To enter and activate the submenu links, hit the down arrow. You will now be able to tab or arrow up or down through the submenu options to access/activate the submenu links.
Contact Us
VA » Health Care » Sheridan VA Medical Center
Sheridan VA Medical Center
Honoring America's Veterans with quality health care services, part of the largest integrated health care ...
Sheridan VA Healthcare System
Grand Opening and Ribbon Cutting Ceremony for the new MHRRTP building.
Can Yoga Ease Your PTSD? VA Wants to Find Out
A clinical research psychologist is exploring the effects of Yoga...
Can Yoga Ease Your PTSD?
A clinical research psychologist with the Department of Veterans Affairs in Indiana is exploring the effects Yoga might have on Veterans suffering with post-traumatic stress disorder. Full Story


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looks as good "in person" as the picture. good quality. we gave this as a gift our son and daughter-in-law and they love it.Read More
very colorful and well madeRead More
This set is great!! The dinner plates are huge, you have so much room on them. The ice cream sized bowls come in handy for everything, and the soup bowls are even big enough to use as a serving bowl. The packaging was very well done, not a broken piece anywhere. Would highly recommend this set.Read More
Excellent quality at a great price. Very happy! Dishes are sturdy & wash well in the dishwasher. Love that they're microwaveable & that they don't get super hot when you take them out of the microwave. Pattern is just like in picture & they look good in the cupboard!Read More
Overstock shipped amazingly fast. The packaging was incredible. I accidentally sent this to my work address - what a shock to see the HUGE box waiting for me! It was all good - my mistake, but don't believe it isn't a HUGE shipment. Great products and super value for the money!Read More
This dinnerware arrived in excellent shape. The outer box was damaged in several places, but the dishes were packed so well (an interior box with 2 layers of bubble wrap and cardboard separating each item) that there was no damage in shipping. I had been skeptical of ordering dinnerware on line, but the price was so good I decided to give it a try. I am quite happy with my purchase.Read More
I was thrilled to see how happy my wife was with our new dinnerware. The plates are an excellent size, the bowls are deep, the cups are 12 ounce which is awesome. I was so happy that every piece was in perfect shape when they arrived, the packaging was top notch. I was also happy that this 40 piece (8 place settings) was a better buy that many (most) of the 32 piece settings.Read More
Eight place setting combined from normal four saves money. Two bowl sizes nice extra choice in cupboard. Larger bowl holds a larger can of soup with room to spare for no spills. Dinner plates are huge for loading up and food not touching if you like it that way like myself! This is a pottery set and not too heavy for most. But smaller hands, arthritis, etc might need some help getting a loaded plate to the table. Colors are rich without being brash. A few sporatic, tiny blemishes in the glaze process adds to the authentic rustic feel of this set. Heats a cup of coffee the way you would expect in a microwave (30-60 secs), unlike ceramics. Pottery only hot from food, no hot spots in pottery itself from microwave use. Just used this set for Thanksgiving and was complimented on the set.Read More
One thing I loved about this set is the style. Another thing I enjoy is there is enough plates and bowls in this set to feed my family of 5 without having to buy 2 separate sets. It was a good experience. Only complain is the large plates don't fit in My dishwasher but overall still very happy. .Read More
My husband and I shopped for new dinnerware extensively both in stores and online. This pattern is one we both like and the price for 8 place settings was excellent. The packing was the best of all, because based on the condition of the outer box when it arrived, I fully expected significant breakage. Instead, every piece was perfect.Read More
My Sango-Vertigo black 40pc arrived today! The outer box was really damaged so I was sure I would find at least a couple of broken pieces. To my surprise, the inner packaging was so protective there was not even a chipped plate. Thanks Overstock! I ordered these to coordinate with my newly redecorated kitchen and everyday use. I was extremely happy to see that the colors were exactly as pictured. And are heavy enough not to break under my family's daily handling.Read More
Sango 'Vertigo Black' 40-piece Dinnerware Set
Today: $141.99


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I love you. I know you are watching your lil sis. You would be such a proud uncle. Scarlett is five now. I think about you everyday. Mom misses you so much. I know dad does too.
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Ecphasis infotech Introduction: Ecphasis infotech private limited company is a leading website and software development and its enhancements services in chennai near vadapalani.We have the experience in this services for past 7+ years.we are pioneer in the service of website designing , software development , mobile application design and development and etc . Vision We are situated at the heart of the chennai city near vadapalani. Our main objective is to satisfy the customers. Our vision is "To become an multi national company within a time span of next 5 years".This is the vision of the company's CEO's,Mr.Nizamdeen Thajudeen and Mr.Karthikeyan of the company. Most of all the customers fully satisfied with our services. Mission: Our mission is very simple but a powerful one "To satisfy the customers with our service" because most of our customers came to us because of customer referrals..To satisfy the customer is a huge and complex task which we learnt through our past experience.When a software is satisfied by a customer , it is said to be quality software. Services Offered: We provide services like Web designing , Website hosting and website redesigning , Website enhancements , software development , website hosting , software testing , software reengineering and its enhancements , customer support , software testing and digital marketing. We have designed and created high quality software products and its enhancements , web designing and its enhancements and mobile application development and its enhancements which are not to be named according to our terms and conditions. Ecphasis infotech Private limited is a reputed company in the service of web designing and software development and its oriented services.We are not just one of the company in chennai, we are "The Best web designing and software development company" in chennai. We have step foot in the service of mobile application development and its enhancements. »» [ Link Details for web hosting services ]
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Graphics Systems is a Print Shop specialized in PREPRESS, PREMEDIA, Graphic Designing. We are one of the best Digital Printers in Coimbatore, Tamil Nadu, India. Printing brochures & Catalogues Designers in Coimbatore. We design trifold, pamphlets & newsletter with creative design Our main aim is to create an identity for your company by utilizing various types of print media. Business Cards printing,Packaging Printing,Banner printing digital printing,offset printing , Brochure printing ,flex printing To Create A Successful Business(Product). »» [ Link Details for 5 Secrets: How To Use Business Cards printing,Packaging Printing,Banner printing digital printing,offset printing , Brochure printing ,flex printing To Create A Successful Business(Product). ]
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We deliver end-to-end website design & development solutions that are mainly focused on client goals and objectives. »» [ Link Details for Website Design Yamunanagar ]
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저희 GNA eMarketing 은 호주 시드니 현지에 기반을 둔 웹사이트 구축, 반응형 사이트,모바일 웹/ 앱, 호스팅,이마케팅, 쇼핑몰 제작을 전문 으로 하는 웹디자인 에이젼시 입니다. We are web design agency/ company Sydney in Australia. We serve responsive web design, shopping mall site, graphic design and web and social marketing like SEO and Rankbuilding . »» [ Link Details for GNA Design ]
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Featherlite Graphics in Grand Meadow, Minnesota expertise in custom vehicle and trailer paint and graphics, vinyl decals, custom airbrushing, stripe decals, vehicle wraps and more. »» [ Link Details for FeatherliteGraphics.com ]
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All Type Of stationary Use In School Office and Factories like Letter pad , bill book , Gate Pass book, school diary , School Hording & Poster Printing , Hording , I-card Designing & Printing »» [ Link Details for School and Institute stationery Printing press ]
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Digitoonz is an interactive entertainment and animation production studio with global presence from USA, UK, Australia, Japan and India. »» [ Link Details for Cgi animation ]
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|Additional Physical Format:
|Online version:
Davidds-Garrido, Yasmin.
Empowering Latinas.
Granite Bay, Calif. : Penmarin Books, ©2001
|Document Type:
|All Authors / Contributors:
Yasmin Davidds
|OCLC Number:
|xii, 244 pages : illustrations ; 22 cm
|A family shattered --
The choice to survive --
Facing the truth about our traditions --
A crisis of self-esteem --
A new perspective of a Latina's relationship with God --
Dealing with la familia --
Taking back the power that belongs to us --
Every child wants an empowered mother --
The courage to change --
Parallels between the Latino culture and the National Football League --
Profiles of courageous Latinas.
|Yasmin Davidds-Garrido.
Addresses a variety of issues Latina women face in the twenty-first century, including sexuality, shame, mental health, and the idea of equality with men, and discusses how they can break through society's boundaries to lead better lives.
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- Families.
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Hotels in Azolimnos
Hotel reservation
Hotel rooms in Azolimnos
There are not so many hotel rooms in Azolimnos, just 26, still everyone can find an offer to suit his choice. The most common offers in this city are apartments, they count 13 out of 26, and their prevalent location is central district. According to our practice, it is the most profitable to book a hotel in the south of Azolimnos, as it is the location of the hotels with optimal cost and quality offers along with the cheap hotels. Taking into account the small size of the city, there is no need to dwell hotel reservation on the location: the road to the city center would take less then half an hour, so one can book a hotel in any district of Azolimnos. The most populated with hotels district of Azolimnos is the center, 77% of cheap hotel rooms are concentrated here. However, even those who want to live in the north can choose from 2 variants of hotel rooms. Azolimnos is an ideal place for couple and family, such travellers rate hotels there 8.9 out of 10 on average. The view to panoramic, garden, pool and sea from the hotel room can serve as a pleasant addition to the journey. Apart from all these, hotels in Azolimnos offer their customers swimming pool, bar, parking and concierge service. The most appreciated amenities in Azolimnos hotels are service and room. According to the visitors reviews, hotels in Azolimnos has great room, fantastic service and great location. Take a look at our selection of the cheap hotel rooms in Azolimnos to make a well-informed choice for your reservation!
Azolimnos cheap hotels
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All cheap hotels in Azolimnos
hotel collections
Azolimnos hotels with swimming pool
average rating
If you like healthy lifestyle, it is very important to train every morning. One of the greatest ways to do it is to swim in the pool! Here is a collection of the cheap hotels with swimming pool in Azolimnos.
Show hotels
Azolimnos hotels with sea view
average rating
Do you want to enjoy beautiful view out of your window? Out of 26 hotels we have selected the best hotels with sea view.
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All hotel collections in Azolimnos
Best hotels in Azolimnos
Hotels in Azolimnos are spread around the city within the distance of 2.3 kilometers, while 21 hotels are located directly in the city center. The most popular accommodations in Azolimnos is
Aigaio Rooms
located in a 0.4 kilometers from the city center. People looking for something extraordinary and exceptional should not pass by
Aigaio Rooms
Aegean Star
Seaside Studios
with view to panoramic, garden, pool and sea. The cost of reservation of such hotel starts from
The best hotels are here and now. Try them!
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Energy in a Cell
Terms Chemosynthetic Organisms that obtain cellular energy by breaking down inorganic chemicals Autotroph creates their own food through photosynthesis or chemosynthesis. These organisms are producers. Heterotroph depends upon other organisms for nutrition. These organisms are consumers. Some organisms, such as the Euglena, will be photosynthetic in the presence of light and heterotrophic without light.
Energy Carriers ATP temporary energy storage molecule in all cells NADH H + and e - carrier molecule NAD + + H + + e - NADH FADH 2 H + and e - carrier molecule FAD + 2H + + e - FADH 2 Think of NADH and FADH 2 as taxi cabs!
NADH and FADH 2
All Cells Need Energy Cells need energy to do a variety of work: Making new molecules Building membranes and organelles Moving molecules in and out of the cell Movement
Where Does A Cell Get Energy? Food is broken down to a form the cell can use. Extra energy is stored in an ATP molecule, a nucleotide.
What Is ATP? ATP – adenosine triphosphate is a molecule made up of an adenine, ribose, and 3 phosphate groups. Adenine Ribose
A Simple Review What basic unit of what organic compound is pictured to the right? Adenine Ribose P
How Does ATP Work? Energy is stored in the bond between the second and third phosphate group. When the bond is broken, energy is released and ADP is formed. Adenine Ribose
ATP – Energy Currency Within a cell, formation of ATP from ADP and phosphate occurs over and over, storing energy each time. As the cell uses energy, ATP breaks down repeatedly to release energy and form ADP and phosphate.
Making Energy Cells make energy in two ways: Photosynthesis – takes place in the chloroplasts. Respiration – takes place in the mitochondria.
Photosynthesis Autotrophs make their own food by trapping light energy and converting it to chemical energy (carbohydrates).
Photosynthesis Using light from the sun, plants combine water and carbon dioxide to make sugar. General Equation: 6CO 2 + 12H 2 O C 6 H 12 O 6 + 6O 2 + 6 H 2 O Reactants Products light
Chemosynthesis Some autotrophs can convert inorganic substances to energy. Most are adapted to live in conditions where there is no oxygen. Marshes Lake sediments Digestive tracts of mammals Deep in the ocean
Cellular Respiration The process of breaking down food molecules to release energy. Aerobic respiration occurs in the mitochondria. Two types: Aerobic – requires oxygen. Anaerobic – requires an absence of oxygen.
Cellular Respiration – Chemical Equation C 6 H 12 O 6 + 6 O 2 _ CO 2 + _ H 2 O + 36-38 ATP enzymes
Cellular Respiration Cellular Respiration Steps Glycolysis Citric Acid Cycle Electron Transport Chain
1. Glycolysis Glucose is split to form pyruvate. Takes place in the cytoplasm of the cell. ATP and NADH are byproducts. Glycolysis Chemical Equation Glucose + 2 NAD + + 2 ADP + 2 Pi 2 pyruvate + 2 NADH + 2 ATP + 2 H 2 O Enzymes
Glycolysis C 6 H 12 O 6 C3H3O4C3H3O4 + NAD + NADH 2 ATP
Review What are the inputs for Glycolysis? Glucose 2 ATP C 6 H 12 O 6 (6 carbon molecule) 2 NAD + (coenzyme) 2 ADP+P What are the outputs for Glycolysis? 2 pyruvic acid (3 carbon molecules) 2 NADH 2 ATP (makes 4 but 2 are needed in the process)
Anaerobic Respiration Two types of anaerobic respiration: Fermentation Occurs when bacteria break down plants (vegetables and fruit) and release alcohol or vinegar. Lactic Acid Fermentation Occurs in muscles – a buildup of lactic acid causes soreness.
Aerobic Respiration 2. Citric Acid Cycle A.K.A. Krebs Cycle Pyruvate is used to build citric acid (a carbon compound), which is broken down to release ATP. (# Net 2 ATP) Takes place in the cristae (the folded membrane in the mitochondrion) CO 2 is released, and NADH & FADH 2 carry electrons and hydrogen ions to the electron transport chain. Each glucose molecule takes two trips around the cycle!
Inputs Pyruvate NAD+ FAD ADP + P i Outputs 4 NADH 1 FADH 2 1 ATP 3 CO 2 Each glucose molecule takes 2 turns through the cycle! Outputs 8 NADH 2 FADH 2 2 ATP 6 CO2
3. Electron Transport Chain Electron Transport Chain Electrons are reduced, and that energy forms large amounts of ATP. (#32-34 ATP) Takes place in the inner membrane of the mitochondrion The used ions are combined with oxygen to form H 2 O.
Electron Transport System 36-38 ATP NADH NAD+ FADH 2 FAD H2OH2O O2O2
Review What are the inputs for the Krebs cycle? 1 Pyruvate (3 carbon molecule) 4 NAD+ 1 FAD 1 ADP + P i What are the outputs for the Krebs cycle? (Per 1 pyruvate – 1 glucose yields 2X) 4 NADH 1 FADH 2 1 ATP 3 CO 2
Review What are the inputs for the ETS per one molecule of glucose? 10 NADH: 8 from Krebs, 2 from glycolysis 2 FADH 2 : from Krebs cycle O2O2 What are the outputs for the ETS? 32-24 ATP molecules H2OH2O
Total ATP Production 36 -38 ATP molecules C 6 H 12 O 6 + 6 O 2 6 CO 2 + 6 H 2 O + 36-38 ATP enzymes
MITOCHONDRION CO 2 H2OH2O O2O2 ATP NADH FADH 2 Heat Electron Transport System ATP NAD + FAD Pyruvate Glucose ATP
Sunlight Photo- System I Photo- system II NADP + ADP NADPH ATP Calvin CO 2 H2OH2O O2O2 ATP NAD + FAD NADH FADH 2 Electron Transport System Cycle Citric Acid Heat CHLOROPLASTMITOCHONDRION ATP Glycolysis Glucose Pyruvate Cycle
Citric Acid Sunlight Photo- System I Photo- system II NADP + ADP NADPH ATP Cycle Calvin CO 2 H2OH2O O2O2 ATP NAD + FAD NADH FADH 2 Electron Transport System Heat CHLOROPLASTMITOCHONDRION Glucose ATP Pyruvate Glycolysis
Cellular Respiration C 6 H 12 O 6 + O 2 CO 2 + H 2 O + 36-38 ATP 666
Oxidation - Reduction Oxidation is the loss of elecrons from an atom or molecule. It is also the loss (removal) of hydrogen atoms from a molecule. A loss of energy is associated with the loss of electrons or hydrogen atoms. Reduction is the gain of electrons or the gain of hydrogen atoms. This process stores energy.
Oxidation - Reduction Oxidation and reduction occur together. When a atom or molecule is oxidized, another must be reduced. Example: Na + Cl ® Na + Cl - - The Na is oxidized; the Cl is reduced.
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"Prague Castle" Castle Tip by la0124
Castle, Prague: 260 reviews and 472 photos
Prague Castle is the most popular sight visited in Prague. It is the largest ancient castle in the world (570 m long, on average 128 m wide, area 7.28 hectares).
Constructed in the 9th century by Prince Boøivoj, the castle transformed itself from a wooden fortress surrounded by earthen bulwarks to the imposing form it has today. Rulers made their own additions so there is a mixture of styles. Prague castle has had four major reconstructions, but it keeps its classical facelift it took on in the 18 century during the reign of Maria Theresa.
The castle has three courtyards and it has always been the seat of Czech rulers as well as the official residence. Allow at least half a day (it does not include time for museum visits) if you want to examine it in depth.
There are several ways in visiting such a beauty and one of the most favored route is walking thru Karluv Most or what tourist would say "Charles Bridge".
Address: Prazsky hrad
Phone: +420 224 373 368
Website: http://old.hrad.cz/
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Delay in Delaware Online Gambling Legalization
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- February 14th, 2013
- By Feelin froggy
This was also announced by the state's recent 'request for proposals' for operators which stated a deadline for operational launch at end September this year.
According to State Lottery director Vernon Kirk, the launch of online gambling in Delaware, which passed a legalization law last year, was planned for Q1-2013, but other priorities, such as the expansion of football parlay betting to non-casino venues, and a state-wide Keno network, had obliged it to delay the implementation to September 2013.
He also said that, due to concerns about player numbers and therefore liquidity in its internet gambling endeavors, , Delaware may seek to close partnerships with other states that have also legalized the pastime.
He stated Nevada and New Jersey as potential partners, adding: "We'll see what New Jersey does, and there's even been discussion that wouldn't necessarily exclude Europe."
Kirk also pointed out to the Request for Proposals which prescribes that respondents must have at least a year's online gambling experience in running legal, real-money online betting operations in Europe or North America.
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Gordon Shearer, president and CEO of Weaver's Cove LNG, told the Standard-Times (Mass.) that he expects his company will pursue an appeal of a U.S. Coast Guard decision to declare the proposed tanker route unsuitable for LNG vessel traffic. Shearer said that the Coast Guard's analysis was based upon "unprecedented procedural and factual errors."
Eversheds Sutherland is an international law firm helping the Fortune 100, industry leaders, sector innovators and business entrepreneurs solve their biggest challenges and reach their business goals. Dedicated to unfaltering excellence in client service, we are known for our business savvy and industry intelligence, providing creative and custom solutions for each of our clients. Industry and business experience makes the difference for our clients.
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Meet us at WindEnergy and WindEurope Summit 2016 in Hamburg!
On September 27-30, the leading wind industry voices will gather at WindEnergy 2016 in Hamburg. Take advantage of this opportunity to speak to representatives from across our business, including senior management.
Throughout WindEnergy 2016, you are invited to visit us at booth A1.521, where we will be showcasing:
Meet a record-breaker: LM 88.4 P
The longest, most advanced, wind turbine blade in the world! Powering an 8 megawatt wind turbine – this rotor is the 'motor' for one of the largest mechanical structures on earth. It has been designed and manufactured with sufficient quality and reliability to withstand 25 years of life offshore, in the harshest weather conditions and roughest seas. Breaking the world record for the longest wind turbine blade, LM Wind Power demonstrates once again our unique technical know-how and manufacturing expertise, enabling today's offshore wind turbines to capture more energy from the wind, reduce the cost of energy and push the industry's boundaries in the battle against global climate change.
You can have it all
Using flexible building blocks, we find the optimum fit for your turbine. LM Wind Power provides customized blades with variable root diameters and lengths while ensuring a fast launch on the global market with economies of scale and competitiveness. This modular concept, combined with LM Wind Power's unique understanding of aerodynamics and loads, has proven to increase Annual Energy Production (AEP) by up to 14% for blades in 2.5-3.3 MW segments. You can have it all: a perfectly optimized blade that leverages LM Wind Power's global supplier base and manufacturing footprint.
GL Certified – Safereceptor Insulated Lightning Protection System
With a track-record of producing more than 125,000 blades with lightning protection systems, we have put that knowledge to work to enable you to capitalize on a competitive GL certified lightning protection (IEC 61400-24 (2010)).
Global Footprint
We have a global manufacturing footprint and are a valued partner in established and emerging markets all over the world. Uniformity in our production processes becomes even more important because of our global manufacturing footprint - across 13 locations and 4 continents. We just opened our second factory in India in Vadodara and we now have an even stronger presence in Asia. Also this year we announced a new factory in Izmir, Turkey. As always we are present where our customers want us to be.
If you are interested in setting up an individual meeting with us during this trade fair, or at another time, please contact Sanne S. Nielsen at firstname.lastname@example.com
Wind Energy Hamburg
WindEurope Summit
Reception: Celebrating the World's Longest Blade
Wednesday, Sept. 28, 16:00-17:00
Visit LM Wind Power's booth for the looooongest blade reception, celebrating the LM 88.4 P. Take a break from a busy day and join us for a drink. We look forward to seeing you!
Presentations at the WindEurope Summit
A new, revolutionary carbon/hybrid technology within thesame global supply chain
Martin Molzen, Sr. Director, Global Business, Marketing & Service
Time: Tuesday, September 27 from 14:30 – 16:00
Location: Hall E at WindEurope Summit
Rotor Design Approach for Extending Wind Turbine Platform Lifecycle
Christian Frank Andersen, Director, Conceptual Design
Time: Tuesday, September 27 from 17:00 – 18:30
Location: Hall G2 at WindEurope Summit
Product Insertion of LM Wind Power Serrations
Ashish Singh, Lead Engineer, Aero Acoustics
Time: Tuesday, September 27 from 17:00 – 18:30
Location: Hall G2 at WindEurope Summit
The Next Blade Frontier
Roel Schuring, Vice President, Engineering
Time: Tuesday, September 27 from 13:00 – 13:10
Location: Speakers' Corner
Meet us
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Here's where you can meet LM Wind Power next.
Global footprint
In 8 countries on 4 continents
With blades factories in all major wind energy markets across four continents, our reach extends beyond anyone else and puts us in pole position to respond faster than competition to the needs of the market.
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LM Wind Power is active on various social media channels. Follow us and stay up to date.


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For a short while during the year I was ten, I thought only people I did not know died. At the time I thought this I was on my summer holidays and we were living far out on Fort Road. Usually, we lived in our house on Dickenson Bay Street, a house my father built with his own hands, but just now it needed a new roof and so we were living in a house out on Fort Road. We had only two neighbors, Mistress Mayvard and her husband. That summer, we had a pig that had just had piglets; some guinea fowl; and some ducks that laid enormous eggs that mother said were big even for ducks. I hated to eat any food except for the enormous duck eggs, hardboiled. I had nothing to do every day except to feed the birds and the pig in the morning and in the evening. I spoke to one one other than my parents, and sometimes to Mistress Maynard, if I saw her when I went to pick up the peelings of vegetables which my mother had asked her to save for the pig, which was just the thing the pig really liked. From our yard, I could see the cemetery. I did not know it was the cemetery until one day when I said to my mother that sometimes in the evening, while feeding the pig, I could see various small, sticklike figures, some dressed in black, some dressed in white, bobbing up and down in the distance. I noticed, too, that sometimes the black and white sticklike figures appeared in the morning. My mother said that it was probably a child being buried, since children were always buried in the morning. Until then, I had not known that children died.
I was afraid of the dead, as was everyone I knew. We were afraid of the dead because we never could tell when they might show up again. Sometimes they showed up in a dream, but that wasn't so bad, because they usually only brought a warning, and in any case you wake up from a dream. But sometimes they would show up standing under a tree just as you were passing by. Then they might follow you home, and even though they might not be able to come into your house, they might wait for you and follow you wherever you went; in that case, they would never give up until you joined them. My mother knew of many people who had died in such a way. My mother knew of many people who had died, including her own brother.
After I found out about the cemetery, I would stand in my yard and wait for a funeral to come. Some days, there were no funerals. "No one died," I would say to my mother. Some days, just as I was about to give up and go inside, I would see the small specks appear. "What made them so late?" I would ask my mother. Probably someone couldn't bear to see the coffin lid put in place, and so as a favor the undertaker might let things go on too long, she said. The undertaker! On our way into town, we would pass the undertaker's workshop. Outside, a little sign read "Straffee & Sons, Undertakers & Cabinetmakers." I could always tell we were approaching this place, because of the smell of pitch pine and varnish in the air.
Later, we moved back to our house in town, and I no longer had a view of the cemetery. Still no one I knew had died. One day, a girl smaller than I, a girl whose mother was a friend of my mother's, died in my mother's arms. I did not know this girl at all, though I may have got a glimpse of her once or twice as I passed her and her mother coming out of our yard, and I tried to remember everything I had heard about her. Her name was Nalda; she had red hair; she was very bony; she did not like to eat any food. In fact, she liked to eat mud, and her mother always had to keep a strict eye on her to prevent her from doing that. Her father made bricks, and her mother dressed in a way that my father found unbecoming. I heard my mother describe to my father just how Nalda had died: she had a fever, they noticed a change in her breathing, so they called a car and were rushing her off to Dr. Bailey when, just as they were crossing over a bridge, she let out a long sigh and went limp. Dr. Bailey pronouncd her dead, and when I heard that I was so glad he wasn't my doctor. My mother asked my father to make the coffin for Nalda, and he did, carving bunches of tiny flowers on the sides. Nalda's mother wept so much that m ymother had to take care of everything, and since children were never prepared by undertakers, my mother had to prepare the little girl to be buried. I then began to look at my mother's hands differently. They had stroked the dead girl's forehead; they had bathed and dressed her and laid her in the coffin my father had made. My mother would come back from the dead girl's house smelling of bay ruma scent that for a long time afterward would make me feel ill. For a while, though not for very long, I could not bear to have my mother caress me or touch my food or help me with my bath. I especially couldn't bear the sight of her hands lying still in her lap.


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Nubuck is a leather that is buffed to look and feel similar to suede. Nubuck is generally more durable than suede and, like many other types of leather, it is often treated to resist wear and tear. That said, a nubuck couch will need cleaning from time to time and knowing a few tricks of the trade may be the difference between you keeping your furniture in tip-top shape and destroying it.
Things You'll Need
- Vacuum
- Nylon brush
- White cloths
- Sandpaper 600-grit
- Cornstarch
Vacuum your nubuck leather couch with a hand vacuum or upholstery attachment. Make sure to suction the cushions and the frame of the couch to get all dirt and dust. Doing this regularly will help prevent dirt and dust from setting in and damaging the couch.
Blot up any liquid spills. Do not rub them or you may spread the moisture or stain.
Pat cornstarch into any stains that are oil-based. Leave the cornstarch on overnight and vacuum it off your nubuck couch in the morning. The cornstarch should help absorb the oil.
Brush the nubuck couch with a nylon bristle brush. This will restore the nap of the leather. Do this from seam to seam using a back and forth motion.
Sand any areas that have noticeable stains with a 600-grit piece of sandpaper. Do this in a back and forth motion, without rubbing too hard.
Vacuum any dust that is created from the brushing and sanding.
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- Photo Credit brown leather furniture image by Leonid Nyshko from Fotolia.com
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An application to the FDA to begin clinical trials of a new drug or biologic on humans. The IND gives the plan for the study and contains formulation, manufacturing and animal test result information.
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Fuji Chemical Industries USA, Inc. is a sales and marketing company servicing the North and South American markets.


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The 10th Invest in ME International ME Conference (IIMEC10) was held, as usual, in the Lecture Theatre at 1 Birdcage Walk in Westminster on May 29th, 2015.
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Treatment, recovery, where to start?!!!...
Discussion in 'General Treatment' started by EnduringAngel, Sep 29, 2013.
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"Yes, yes, yes," cried Sam Torrance. "Ooh, ooh, ooh," groaned Peter Alliss. People call golf a passionless game, but clearly they forget Augusta, where birds chirrup the spring's glad tidings from pine to pine, where azaleas riot in fertile protuberance and where, if you crouch quietly by your television set, you will soon enough hear the unmistakeable call of the golf commentator coming into season.
They love it out there, don't they? If you'd had a dollar for every time Gary Lineker paused to hymn the majesty of "this glorious course", you'd have earned more last week than Gary Player's


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funny glass storage of Clayre & Eefideal for storage of food or sweetsgreat use as decoration idea
Design: A jar of 3 floors without frillsMaterial: GlassColor: transparentProduct Size: Ø 16x41 cm
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