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Whether it's the start of summer or the end of the school year, June means many things to many people.
For the lesbian, gay, bisexual and transgender (LGBT) community, it's also Pride Month -- and each week, revelers will be hitting cities both nationwide and around the world to mark the occasion.
This year, HuffPost Gay Voices hopes to acknowledge LGBT Pride in a very special way -- and we'd like to hear from you! Here's your chance to be featured on the Huffington Post!
Please end us a photo of you, along your significant other and friends, celebrating LGBT Pride in your city, along with some details.
ALL ENTRIES MUST include your first name and that of your friends (if applicable), along with the date and location of the Pride event you're attending.
A short (6 lines or less) anecdote telling us about the experience would be great, too!
Send your submissions to firstname.lastname@example.com and have your Pride photo featured on the HuffPost Gay Voices page next week!
DISCLAIMER: By sending us your photo and anecdote, you are giving us permission to consider publishing them on our page, as well as distributed via our Twitter, Facebook, Tumblr and Instagram accounts.
Take a look at some great LGBT Pride photos from Tel Aviv below:
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Check rates!
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Pets are allowed on request. No extra charges.
This property only accepts cash payments.
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Hotels Shennongjia
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subset: commoncrawl


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A TAX AVOIDANCE SCHEME ring-fencing some £156m from the public purse has been shut down after a first-tier tribunal ruling.
The scheme, devised by NT [No Tax] Advisors and sold by Dominion Fiduciary Serves Group, had 305 users. It was challenged by HM Revenue & Customs investigators after they identified a series of financial transactions involving loan notes worth £6 million which were intended to exploit the tax rules on stock lending.
However, the tribunal found the arrangement was based on little more than "signing pieces of paper and making entries into accounts". The money moved in a circle and the tribunal held it served no other purpose than to save tax, adding that had the scheme proved successful, it would have been tantamount to making income tax voluntary.
It is the second scheme in as many months that NT Advisors has been publicly associated with, after it emerged that its founder also set up the Cup Trust, a registered charity used as a front for another avoidance scheme saving investors £46m in tax and artificially generating Gift Aid.
Speaking after the ruling, HMRC's director-general for business tax Jim Harra said: "People who are tempted by this type of scheme should be warned that they carry serious risks. These include paying advisors expensive set-up charges, which can run into hundreds of thousands of pounds, on top of tax that is due and interest for late payment.
"HMRC will challenge these schemes, however complex they appear to be. We have the skills and the expertise to effectively challenge tax avoidance and we will continue to do so."
Related reading
Edwin Coe recruits HMRC operational head of fraud investigation team
At HMRC, Dmitri Surendran was responsible for leading the London team of the offshore, corporate and wealthy unit of the fraud investigation service
Fifth of micro-businesses unaware of Making Tax Digital
Research also finds that 84% of businesses believe that the government has not provided enough information about digital tax plans
Tax fraud loses HMRC £16bn
A total of £16bn was lost through tax fraud last year, according to estimates released by Pinsent Masons
The rising significance of inheritances
Rosamond McDowell looks at key changes to inheritance tax policy, which apply from April this year


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Leigh Hunt
Life, Poetics, Politics
Edited by Nicholas Roe
Format: Hardback
Normal Price: $212.00
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Leigh Hunt by Nicholas Roe
Book DescriptionRecent critical and scholarly interest in John Keats has encouraged a resurgence of interest in his friend and mentor, the poet and journalist Leigh Hunt. This timely collection of essays by leading British and North America romanticists explores Hunt's life, writings and cultural significance over the full length of his career, arguing for the recognition of Hunt's importance to British intellectual and literary culture in the Romantic period.
Buy Leigh Hunt book by Nicholas Roe from Australia's Online Bookstore, Boomerang Books.
Book DetailsISBN: 9780415309844
(234mm x 156mm x 20mm)
Pages: 264
Imprint: Routledge
Publisher: Taylor & Francis Ltd
Publish Date: 27-Mar-2003
Country of Publication: United Kingdom
Other Editions...
Books By Author Nicholas Roe
Leigh Hunt, Paperback (August 2014)
Recent critical interest in Keats has encouraged a resurgence of interest in his mentor, Leigh Hunt. This collection of essays explores Hunt's life, writings & cultural significance, arguing for the recognition of Hunt's importance to British intellectual & literary culture in the Romantic period.
John Keats, Paperback (June 2013)
An entirely new portrait of Keats, rich with insights into the torments of his life and the imaginative sources of his works
English Romantic Writers and the West Country, Hardback (May 2010)
Long confounded with a monolithic British entity or misrepresented as 'Lakers' and 'Cockneys', the diverse regional forms of 'English Romanticism' are ripe for reassessment. Ranging west of a line between the Wye at Tintern and Jane Austen's Chawton, this book offers a first reconfiguration of Romantic culture in terms of English regional identity.
Keats and History, Paperback (August 2007)» View all books by Nicholas Roe
Critical approaches to Keats's poems which place his work in historical and political context.
» Have you read this book? We'd like to know what you think about it - write a review about Leigh Hunt book by Nicholas Roe and you'll earn 50c in Boomerang Bucks loyalty dollars (you must be a member - it's free to sign up!)
Author Biography - Nicholas Roe
Nicholas Roe is Professor of English at the University of St Andrews, Scotland. His books include John Keats and the Culture of Dissent (1997) and, as editor, Keats and History (1995) and Samuel Taylor Coleridge and the Sciences of Life (2001).
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This digital audiobook was created from the only remaining analog source and contains a slight tape hiss.
When Jacques Lusseyran was an eight-year-old Parisian schoolboy, he was blinded in an accident. He finished his schooling determined to participate in the world around him. In 1941, when he was seventeen, that world was Nazi-occupied France. Lusseyran formed a resistance group with fifty-two boys and used his heightened senses to recruit the best. Eventually, Lusseyran was arrested and sent to the Buchenwald concentration camp in a transport of two thousand resistance fighters. He was one of only thirty from the transport to survive. His gripping story is one of the most powerful and insightful descriptions of living and thriving with blindness, or indeed any challenge, ever published.
©2014 New World Library (P)2014 New World Library
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"One of the three most important books in my life"
I read this book for the first time about 30 years ago and subsequently visited the town of his boyhood, Jurvardeil. So much profound wisdom. I would recommend it to anyone, but especially teenagers who are struggling to find meaning and purpose in life.
"Moving account"
A powerful story well narrated. As much about the human capacity for understanding and compassion as it was a recounting of WWII. Unfortunate that it was abridged. The gaps left you wondering.
This is a beautiful story of a good man and his honest testimony. It has inspired and humbled me. If you, like myself, are yearning for some small ray of heaven's light to shine through the hellish evil of the holocaust, please listen to this.
"A Must Read"
There are few, if any, books I would recommend more highly. This book is worth your time.
"Absolutely amazing"
What an amazing man. I don't know what else to say. Words cannot express how much i recommend this title. The first horror story of ww2 suffering made beautiful.
Poetically told, dramatic, haunting, hopeful..
I would have loved to have met this writer.. Im sure i will in heaven.
"Not well written"
This is in no way meant to trivialize what the author went through. It is truly a story of heroism and triumph. However, i was just not a fan of the way it was written. I was bored.
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text: Seller: don3092 (416) 100%, Location: Lincoln, Nebraska, Ships to: US & many other countries, Item: 192038171978 For sale is an old screw jack metal bracket. It approximately 9" long. The lift distance is approximately 5". Please check out the photos. I don't offer returns so email any questions. Shipping prices are within continental USA only. Other USA bidders please email for shipping costs. International shipping through the Global Shipping Program only. Payment is due within three days of auction end. Thanks for looking.


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Let us know when your receive great advice so we can thank our lawyers and point others with similar questions in the right direction.Got it!
i was arrested recently & charged with controlled substance, hypo needles loitering. Im currently on ACOD for marijuana possesion and have other charges pending in a different county. the cop offered me the option of "working" for them and setting up a drug deal if i did my new charges will be dropped. Do they really drop your charges or is that just an insentive? I have a legal aid she adviced me not to do it for the fact that if the person finds out i set them up they will be out for me. Can the police tell them it was a set up? Am i protected in any way? I heard the statement you write can be public knowledge & you can even look up whos a "snitch" online. A friend of mine was arrested for dealing and he told me the cops told him it was indeed a set up who did it. Whats the real deal?!
There are no specific "details." There is no on-line database to learn who snithces are. If you are serious about this you want to become a registered informant and put the specifics in writing so the police later cannot say you were not authorized to do what they ask you to and instead arrest you again. Your lawyer should be involved in this because it is up to the DA - not the police - to resolve your current case. If your lawyer won't help with this I suggest you retain a lawyer who will. Please understand that often it is not hard for someone to figure out who set them up... its usually the person they were dealing with prior to the arrest.
I am a former federal and State prosecutor and now handle criminal defense and personal injury/civil rights cases. Feel free to check out my web site and contact me at (212) 385-8015 or via email at email@example.com. The above answer is for informational purposes only and not meant as legal advice.
You need your own attorney to advise you. It's not as simple as a cop tells you it is.
I am a criminal defense attorney practicing in Nassau, Suffolk and New York City. The above information is not a substitution for a meeting whereas all potential legal issues can be discussed.
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Tooth wonders.
Is it true that chewing and brushing your teeth with neem twig everyday can cure and heal almost every problem of tooth.
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Doctor Answers (1) on Tooth wonders.
Dr. Sumit Kumar Misra
6 yrs. of exp | Lucknow | Dental Surgeon
Well neem undoubtedly has excellent effects on health but neem twig is not efficient in cleaning out the debris and plaque present between the tooth or the inaccessible areas of mouth..failure in removal may lead to caries and gum problems..better go for toothbrush and a tooth paste..
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Nancy L. Russo, Brian Fitzgerald, Janice I. Degross
Realigning Research and Practice in Information Systems Development - The Social and Organizational Perspective (International Federation for Information Processing, Volume 194)
Книгу можно купить в интернет-магазинах:
· OZON.ru 5179р. [Проверить наличие]
ISBN: 0792374207Издательство: Kluwer Academic Publishers
Given the pervasive nature of information technology and information systems in the modern world, the design and development of IS and IT are critical issues of concern. New research topics continuously emerge in tandem with the latest developments in technology-E-Business, Knowledge Management, Business Process Reengineering, for example. However, when the initial flurry of research abates and the "gloss" of these areas has diminished somewhat, as it inevitably does, the enduring core issue remains as to how to develop systems to fully exploit these new areas. Both information systems and information technology are interpreted fairly broadly in this book. Of particular interest to the editors were research studies that facilitate an understanding of the role and impact of information technology on society, organizations, and individuals, and which strive to improve the design and use of information systems in that context. The contributions to the book are categorized into...
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Manage inventory and sales channels
Tools and services for Amazon sellers
Tools and services for eBay sellers
Handle challenges of cross-border trade
Sell on social media and web stores
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looks like the Refund and Return options are not valid / offered by eBay for UK site. They are only available for UK, Canada and Australia sites. That is the reason you don't have a way to specify this information in Listing Form. Let me know if I can be of any further help.


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Severe hairfall & itching
I have severe hairfal and itching scalp all the time.tried many oils, tried calcium and iron capsules for 2 months my weight got increased, tried homeopathy for 1 month no improvement.
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Doctor Answers (1) on Severe hairfall & itching
Dr. Manoj Agarwala
11 yrs. of exp | Delhi | Dermatologist
94 %
INR 250 for 24 hrsCHAT NOW
Thanks for the query. Severe dandruff could indicate dandruff itself which is significant or can indicate beginning of some other skin condition like Seborrheic dermatitis or Scalp psoriasis. Based on your description of pain on the scalp it looks like a superficial bacterial infection usually caused by staphylococcus aureus. Sometimes they co-exist with fungal folliculitis and can be determined with more precision during a consultation. Kindly consult a dermatologist for exact diagnosis and treatment plan. It is also important to prevent their relapse once you have got it cured. A decolonization regimen suggested by your doctor will help.
Health Tips
You can consult me for personal recommendation on Practo Direct.
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I was down Orange County way earlier today and thought I'd check out this little place located in Santa Ana. It's a small, clean place in a strip mall setting, but don't let that stop you! There have been previous threads on Jerry's that were mostly favorable and I have to agree. The dogs were really good.... char-grilled.... and all the condiments were fresh and tasty. I accompanied my meal with their freshly cut and cooked to order potato chips. Something different that really hit the spot. All in all, I would definitely recommend this place. I was very pleasantly surprised......
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Welcome fading!!
Yes dentist is very important. I am due for a check up in Oct.
Sent from my HTC One SV using The Bub Hub mobile app
Welcome fading!!
Yes dentist is very important. I am due for a check up in Oct.
Sent from my HTC One SV using The Bub Hub mobile app
I've got a friend who stayed with me long term board free, who is finally in a position where she can pay me back the money she promised I would always get. It's only gonna be about $2.5k I think (technically she owes me more like 6 lol.... But we won't go there!!!)
But that will be a nice little bit to chop off the top of the debt.
We are officially $10k down from where we started, so I'm so super proud of our efforts. Need to keep pushing harder though, if we want to finish in time!!!!!
Ugh why are finances always such an issue. Sometimes I really hate money and the issues it brings
Anyway we should count ourselves lucky we live in Australia with so much more than others. Good job on the debt payoff mrst you should be really proud!!
Still trying to forget mums jibes
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It's hard isn't it hope :-( I'm married to my husband of 6 months, who I've been allowed to call mine for over 6 years, and yet his mother still treats us like children and lectures us and tells us ton"slow down" and "we are making a big mistake". I don't even know what mistake she thinks we are making, because we haven't even told her we are tying for children. Parents are difficult creatures!!
I guess parents will always worry about something. It sucks that you're getting grief from your mum Hope. Try not to let it bother you because only you and your DH know how you feel and what you've got. As long as you both feel comfortable and like that time is right, that is the only thing that matters.
I get that money is needed to buy the baby the things he/she will need along the way it does not mean that you need to be rolling in it. There is always a way to make it work and you work with the budget you have. Besides people always live to their means - so with that said even the rich would need to make changes or sacrifices to afford children There is always a way!
Sorry to the essay it's early and I'm not very articulate at this time of day haha
Two girls, one dream and baby you are it!
Lol rain I think u were very articulate :-)
It's so true that people live to their means. I took a different job which meant a $20k pay cut pretty much. It was a hard decision to make but I still maintain it was the right choice.
I thought it was going to be really difficult financially, yet here we are paying $10k off our debt in under a few months. You can achieve anything if its important enough to you.
Thanks so much for the support girls. I am a sensitive soul so it helps me see the whole picture, rainbow you are so right. It is up to dh and I and I just need to trust that that's ok. Its just offensive because you want your fam to back the decisions you make. I said to mum, well there are ppl who have five kids and don't have much money and they get by, she said yes but life is simpler. I get it, she wants me to have the best and give my kids that, but I wish she realized that just because she thinks a certain way, doesn't necessarily mean its the right way or everyone has to agree to it and do what she says! I think that is a key fault in parent child relationships..similar to what your mil says mrst. And you feel like a two yr old, so not cool.
Also rain when you said the rich cut down too when a bub comes, that's right you always live to your means. Just because you're well off doesn't mean you're child is going to have things better. What is materialism going to give them in the long term. And half the time ppl achieve wealth because they work ridiculously hard and as a result can't be home as much with their kids. Its the value you put on money and as I said before, my fam is a tad into it
On a lighter note, very well done mrst!!! 10k is awesome. Imagine how much you'll save when you're utd,maybe even more
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Hopefully we can continue saving in this trend, it's not easy as we have no self control lol.... I've been talking DH with about backpacking through Europe before settling down. Maybe 3-4wks worth. Still discussing the possibility, but I think it's the most cost effective way for me to get my travel bug under control before we are house ridden for approx 10 years (I'm not much a fan of taking young children on holidays, but that's another discussion haha)
Timing wise, it would probably we JUST before we start TTC, or even we could start our first cycle while away (dames having to pack one extra item - condoms hahaha).
Still not sure f it's the right thing to do tho....
I have the same thing going on. Caravanning around France. I don't think its the right time for us tho. I'd rather TTC in March because if we travelled it'd be Sept so too long to wait for me
Could be a good decision mrst especially if you've got the bug!! Dh and I have Bali in Jan so that should kerb things for a bit and we have traveled a bit between us, so I hope we can hold out for a few yrs for Europe
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DH has been to NZ 3 times, and Delhi (both for work). We have been to Bali n New Zealand together. Thailand for our honeymoon. So sure better than some, but never truly gone very far... All above could really be considered Australia still HAHA.
Really want a big one, and could be fun to make a "thing" out beginning TTC. Some go to a fancy hotel, we go to Europe hahha.....
Suppose just need to do up a budget, and see if we can justify it... Either way we will do SOMEthing. Maybe just a week in Ireland or something like that :-)
Pregnant for the first-time?
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Quick Links
Online Free & Reduced Lunch Application
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Coming Soon . . . .
STEAM NIGHT! March 16th 5:30p.m.-7:30p.m.!
pennies for patients
Students across the country are collecting pennies, nickels, dimes and quarters during the Pennies for Patients campaigns benefiting the Leukemia & Lymphoma Society. Wagner-Holt is excited to be part of this fundraising endeavor.
Counseling Services
Please visit the Lodi Unified counselor website for information on counseling services and to view the counseling newsletter.
Fifth Grade STEM activity
Spelling Bee
Friday Morning Announcements
CAASP Parent Information
Parent Resources for Understanding the Student Score Report
The video "Understanding the CAASPP Student Score Report 2015–16," which explains how to interpret student results and highlights the new features found in the report, is now available in English. It is located on the California Department of Education (CDE) CAASPP Student Score Report Information Web page. The Spanish version of the video is coming soon.
A CAASPP document, Understanding Your Student Score Report, is now available in English for each of the following on the Understanding the CAASPP Student Score Reports Web page:
Each document will be available soon in Spanish and other languages.
Shining Stars and Olympic Day Highlights!!
STEAM Night! March 16th 5:30-7-30!
Upcoming Events
Friday, February 10 Holiday- No School
Wednesday, February 15 Minimum Day
Monday, February 20 Holiday- No School
Wagner-Holt Elementary has a New ORCA Creed!
ORCA's take OWNERSHIP by being
Organized Responsible, Respectful,
Engaged Community Members
who strive for Achievement
SPD Traffic Safety Reminder
The Stockton Police Department asked us to remind each of you to be mindful of traffic laws, especially during drop off and pick up at schools. Remember that traffic in both directions must stop when ...more
AVID Elementary
As an AVID (Advancement Via Individual Determination) campus, we are striving to ensure that all of our students are ready for college. Additional information about AVID on our campus will be provided soon. Please visit the website to view the successes of the 30 year program. AVID Elementary
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I think choosing a wedding venue is one of the most important decisions you'll make during the wedding planning. This is especially true if you're like Dave and I, and had the ceremony and reception at the same venue. Quite often, venues have onsite catering as well. So you're not just choosing the space for the wedding, but the food as well! The staff will set up the ceremony and reception, serve dinner, make sure everything runs smoothly, etc. It's an important decision.
Dave and I loved our wedding venue. Their on-site wedding coordinator was a God send, and the banquet staff was amazing! They really had a beautiful set up. Today I'm going to share a few tips with you to make sure you end up with an amazing wedding venue as well!
1. Consider your budget.
The venue (including catering) accounted for half of our wedding budget, so it wasn't a decision we made lightly. I figured out how much the food and drink would cost given how many people we were inviting. This gave me an idea of where our final number would be. I also considered any upgrades we would need to pay for along the way (audiovisual equipment, extra hours on the bar, etc).
2. Consider your guest list.
Make sure the venue has more than enough space. If the venue claims to hold 250 people and you're inviting 250, it's too small for you. Find a venue that holds more people than you're inviting so everyone has some breathing room.
3. How much work are you willing to take on?
Some wedding venues have staff that set everything up for you, including whatever décor you bring. Some won't. Our venue set up the hanging lanterns and the tables, but we were in charge of our décor. If you don't feel like you'll be able to manage that, make sure to find a venue that will do it for you.
4. What kind of wedding are you having?
Make sure the venue matches the tone of your wedding. If you're having a black-tie princess wedding, a rustic barn isn't going to work. On the other hand if you're going for a rustic wedding with lots of burlap and hay bales, probably don't go for the country club.
5. The weather factor.
I'm all for outside ceremonies. Hell, I wanted to have one myself. And I certainly planned on it, until it was pouring on my wedding day. Luckily, the venue had a back-up plan. If you're having an outside wedding as well, make sure there is a Plan B available!
6. Book early!
Wedding venues are typically one of the first things people book, so they're getting scooped up quite a bit in advance. Dave and I booked our venue 18 months before the wedding!
What are some tips you'd like to pass along for choosing a wedding venue?
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text:
Environmental Tectonics Corporation's Sterilization Systems Group Announces New Project Awards in All Categories
William F. Mitchell, President and Chairman of ETC, stated, "We are verypleased to have been selected for these new contracts. These new contractsspan all of our product offerings within the Sterilization Systems Group, eventhose in our newly formed Professional Service Group. Our SterilizationSystems Group is uniquely positioned within our respective industries todelivery highly customized solutions to the industries most demandingrequirements. No other competitor offers the array of products and servicesthat match ETC's SSG."
ETC's Sterilization Systems Group offers steam and Ethylene Oxidesterilizers, Services, Consulting and Software Systems to the Medical Device,Pharmaceutical, Biotechnology and Healthcare industries. ETC's SSG offersunique, customized solutions to unique process systems challenges.
ETC designs, develops, installs and maintains aircrew training systems,public entertainment systems, process simulation systems (sterilization andenvironmental), clinical hyperbaric systems, environmental testing andsimulation systems, and related products for domestic and internationalcustomers.
This press release may include forward-looking statements within themeaning of Section 27A of the Securities Act of 1933 as amended, and Section21E of the Securities Exchange Act of 1934. We have based these forward-looking statements on our current expectations and projections about futureevents. These forward-looking statements are subject to known and unknownrisks, uncertainties and assumptions about the Company that may cause ouractual results, levels of activity, performance or achievements to bematerially different from any other future results, levels of activity,performance or achievements expressed or implied by such forward-lookingstatements. In some cases, you can identify forward-looking statements byterminology such as "may", "will", "should", "could", "would", "expect","plan", "anticipate", "believe", "estimate", "continue", or the negative ofsuch terms or similar expressions. Factors that might cause or contribute tosuch a discrepancy include, but are not limited to, contract cancellations,failure to obtain new contracts, political unrest in customer countries,unfavorable results in litigation, general economic conditions, and thoseissues identified from time to time in our Securities and Exchange Commissionfilings and other public documents, including, without limitation, our AnnualReport on Form 10-K for the fiscal year ended February 23, 2007.Contact: Duane D. Deaner, CFO Tel: 215-355-9100 (ext. 1203) Fax: 215-357-4000 ETC -- Internet Home Page: http://www.etcusa.com
SOURCE Environmental Tectonics Corporation
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Neochemir Inc., Kobe University and Co2Be Medical Engineering K.K. | Date: 2012-07-13
The present invention provides a prophylactic or therapeutic agent for fracture and bone diseases as well as a bone growth promoting agent containing carbon dioxide as an active ingredient. Further, according to the present invention, an additive or synergistic effect for preventing or treating fracture and bone diseases as well as for promoting bone growth by combining the therapeutic agent of the present invention and a bone absorption inhibitor and/or a bone formation promoter is obtained.
Neochemir Inc., Kobe University and Co2Be Medical Engineering K.K. | Date: 2013-09-25
A liquid medicine of the present invention comprising liquid having carbon dioxide dissolved therein, said liquid being administered by using means of liquid injection, and a method of treatment of the present invention using a liquid medicine comprising liquid having carbon dioxide dissolved therein, said liquid being administered by using means of liquid injection can reduce or eliminate tumors with few side effects. When the liquid medicine of the present invention comprising liquid having carbon dioxide dissolved therein, said liquid being administered by using means of liquid injection, and the method of treatment of the present invention using a liquid medicine comprising liquid having carbon dioxide dissolved therein, said liquid being administered by using means of liquid injection are used in combination with surgical therapy, chemotherapy, radiotherapy, or immunotherapy of tumors, effects can be enhanced or side effects can be reduced compared with monotherapy or multidisciplinary therapy thereof.
Regulation of mitochondrial proliferation by PGC-1α induces cellular apoptosis in musculoskeletal malignancies
Onishi Y.,Kobe University |
Ueha T.,NeoChemir Inc. |
Kawamoto T.,Kobe University |
Hara H.,Kobe University |
And 5 more authors.
Scientific Reports | Year: 2014
A number of studies have reported that decreased mitochondrial numbers are linked with neoplastic transformation and/or tumor progression, including resistance to apoptosis. Peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) is a multi-functional transcriptional coactivator that regulates the activities of multiple nuclear receptors and transcriptional factors involved in mitochondrial biogenesis. In this study, we observed that the number of mitochondria in sarcoma tissues, such as osteosarcoma and malignant fibrous histiocytoma, is significantly lower than that in normal muscle tissue or benign tumors, and that increasing the number of mitochondria by PGC-1α overexpression induces mitochondrial apoptosis in human sarcoma cell lines. The findings suggest that decreased mitochondrial numbers may contribute to musculoskeletal tumor progression, and that regulation of mitochondrial numbers by PGC-1α could be a potent therapeutic tool for human malignancies. © 2014 Macmillan Publishers Limited. Source
Transcutaneous Application of Carbon Dioxide (CO2) Induces Mitochondrial Apoptosis in Human Malignant Fibrous Histiocytoma In Vivo
Onishi Y.,Kobe University |
Kawamoto T.,Kobe University |
Ueha T.,NeoChemir Inc. |
Kishimoto K.,Kobe University |
And 9 more authors.
PLoS ONE | Year: 2012
Mitochondria play an essential role in cellular energy metabolism and apoptosis. Previous studies have demonstrated that decreased mitochondrial biogenesis is associated with cancer progression. In mitochondrial biogenesis, peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1α) regulates the activities of multiple nuclear receptors and transcription factors involved in mitochondrial proliferation. Previously, we showed that overexpression of PGC-1α leads to mitochondrial proliferation and induces apoptosis in human malignant fibrous histiocytoma (MFH) cells in vitro. We also demonstrated that transcutaneous application of carbon dioxide (CO2) to rat skeletal muscle induces PGC-1α expression and causes an increase in mitochondrial proliferation. In this study, we utilized a murine model of human MFH to determine the effect of transcutaneous CO2 exposure on PGC-1α expression, mitochondrial proliferation and cellular apoptosis. PGC-1α expression was evaluated by quantitative real-time PCR, while mitochondrial proliferation was assessed by immunofluorescence staining and the relative copy number of mitochondrial DNA (mtDNA) was assessed by real-time PCR. Immunofluorescence staining and DNA fragmentation assays were used to examine mitochondrial apoptosis. We also evaluated the expression of mitochondrial apoptosis related proteins, such as caspases, cytochorome c and Bax, by immunoblot analysis. We show that transcutaneous application of CO2 induces PGC-1α expression, and increases mitochondrial proliferation and apoptosis of tumor cells, significantly reducing tumor volume. Proteins involved in the mitochondrial apoptotic cascade, including caspase 3 and caspase 9, were elevated in CO2 treated tumors compared to control. We also observed an enrichment of cytochrome c in the cytoplasmic fraction and Bax protein in the mitochondrial fraction of CO2 treated tumors, highlighting the involvement of mitochondria in apoptosis. These data indicate that transcutaneous application of CO2 may represent a novel therapeutic tool in the treatment of human MFH. © 2012 Onishi et al. Source
Uefuji A.,Kobe University |
Matsumoto T.,Kobe University |
Matsushita T.,Kobe University |
Ueha T.,NeoChemir Inc. |
And 3 more authors.
American Journal of Sports Medicine | Year: 2014
Background: The anterior cruciate ligament (ACL) does not heal spontaneously after injury, and patients of different ages respond differently to treatment. CD34+ stem/progenitor cells derived from the ACL remnant and associated tissues contribute to tendon-bone healing, but the relationship between age and the ACL's healing potential has not been clarified. Hypothesis: The ACL remnant and associated tissues from adolescent patients have more CD34+ cells, and this population of cells from younger patients exhibits a higher potential for proliferation and differentiation in vitro. Study Design: Descriptive laboratory study. Methods: Ruptured ACL remnants and associated tissues were harvested from 28 patients (mean age, 24.6 ± 1.6 years) who had undergone primary arthroscopic ACL reconstruction. Patients were divided into 3 patient groups by age: 10-19 years (teens group; n = 10), 20-29 years (20s group; n = 10), and ≥30 years (30s group; n = 8). The ACL remnant cells were characterized using fluorescence-activated cell sorting (FACS). Expansion potential was evaluated using population doubling (PD), and multi-lineage differentiation potential was assessed and compared. Results: The FACS analysis showed numerous CD34+ cells in the teens group compared with the 30s group (mean, 25.4% ± 7.9% vs 16.9% ± 3.9%, respectively; P = .044). The PD results indicated that the teens group had a significantly higher expansion potential than the 30s group at passage 3 (mean, 3.3 ± 0.2 vs 2.8 ± 0.2, respectively; P = .039). Young ACL remnant cells had a higher potential for osteogenic differentiation according to alkaline phosphatase activity (teens group, 169.5 ± 37.9 × 10 ng/mL vs 30s group, 64.9 ± 14.6 × 10 ng/mL; P = .029) and osteocalcin gene expression (teens group, 1.0 ± 0.25 vs 30s group, 0.39 ± 0.01; P = .01). In addition, the teens group displayed a higher differentiation potential to angiogenic lineages (acetylated low-density lipoprotein/Ulex europaeus lectin-stained cell counts) than other groups (teens group, 15.9 ± 1.9 vs 20s group, 8.9 ± 1.3 [P = .04]; teens group, 15.9 ± 1.9 vs 30s group, 7.2 ± 1.5 [P = .008]) and also tube length (teens group, 6939 ± 470 |xm vs 30s group, 4119 ± 507 |xm; P = .009). Conclusion: The ACL remnants of adolescent patients had more CD34+ cells, and those cells had a higher potential for proliferation and multilineage differentiation in vitro. Clinical Relevance: During remnant-preserving or remnant-transplanted ACL reconstruction, surgeons should consider the patient's age when predicting the healing potential. © 2014 The Author(s). Source


text:
The overall goal of this proposal is to develop and evaluate PET imaging methods for measuring activity and distribution (mass) of brown adipose tissue (BAT). This is relevant to the current request for applications: "Human brown adipose tissue: Methods for measurement of mass and activity", RFA-DK-10-002. Type-2 diabetes mellitus, T2DM, previously known as "noninsulin-dependent diabetes mellitus" (NIDDM) or "adult- onset diabetes", is the most common form of diabetes. About 90 to 95 percent of people who have diabetes have T2DM. There are 23.6 million people in the United States, or 8% of the population, who have diabetes. The total prevalence of diabetes increased 13.5% from 2005-2007 according to the American Diabetes Association. BAT has been shown to have thermogenic properties and can reduce white adipose tissue. It may be an important drug target for preventing or treating obesity. Our goal is to develop new imaging methods that will allow measurement of BAT activity and mass. We propose to use the adrenergic system for measuring both activity and distribution (mass) of BAT. The direct involvement of adrenergic system (epinephrine/norepinephrine and ?3 adrenergic receptor) via the uncoupling protein (UCP) in BAT thermogenesis has been reported. The ?3 adrenergic receptor has therefore been pursued as a target for therapeutics development for BAT activation. We propose to investigate two approaches towards activation of BAT using the rodent model by using a ?3-adrenoreceptor agonist, CL 316243 and the norepinephrine transporter (NET) blocker, tomoxetine. Both approaches are expected to stimulate the adrenergic system and increase BAT 18F-FDG in MicroPET/CT imaging. For measuring BAT mass we will develop 11C-CL 316243 as a selective ?3-adrenergic agonist radiotracer for imaging BAT distribution and mass, and also evaluate the NET radiotracer 18F-MFP3 as a potential radiotracer for measuring BAT distribution and mass. One of our goals is to evaluate BAT activity and mass using 18F-FDG and 11C-CL 316243 in the diet-induced obesity rodent model. Radiation dosimetry studies of 11C-CL 316243 will be carried out on rodents for an exploratory Investigational New Drug (eIND) application for translation to human studies. Development of the adrenergic neurotransmitter receptor imaging methods will strongly complement ongoing imaging approaches for obesity and diabetes.
This is a request for developing a noninvasive PET imaging methodology for the study of brown adipose tissue (Good fat). Diabetes is a major health problem currently affecting the US. Increased metabolic activity in the brown fat can accelerate breakdown of white adipose tissue (Bad fat) that is responsible for type 2 diabetes. The proposed research will develop methods to measure the metabolic activity and mass of brown adipose tissue. NOTE: The criteria scores and the critiques given below were provided by the reviewers assigned to this application. These do not necessarily reflect the positions of the reviewers at the close of the group discussion or the final majority opinion of the group, although the reviewers were asked to amend their criteria scores and critiques if their positions changed during the discussion. Please note that the criteria scores are not averaged in arriving at the final overall impact scores. If the reviewers have not changed their criteria scores after the discussion, those shown in the critiques may reflect the opinion of the reviewers before the meeting. The Resume and other initial sections of the summary statement are the authoritative representations of the final outcome of the group discussion. If there is any discrepancy between the reviewers'commentaries and the priority/impact score on the face page of this summary statement, the priority/impact score should be considered the most accurate representation of the final outcome of the group discussion.
|Kaur, Jasmeet; Khararjian, Armen; Coleman, Robert A et al. (2014) Spinal cord dopamine D2/D3 receptors: in vivo and ex vivo imaging in the rat using (18)F/(11)C-fallypride. Nucl Med Biol 41:841-7
|Pandey, Suresh K; Kaur, Jasmeet; Easwaramoorthy, Balu et al. (2014) Multimodality imaging probe for positron emission tomography and fluorescence imaging studies. Mol Imaging 13:1-7
|Mirbolooki, M Reza; Upadhyay, Sanjeev Kumar; Constantinescu, Cristian C et al. (2014) Adrenergic pathway activation enhances brown adipose tissue metabolism: a [¹?F]FDG PET/CT study in mice. Nucl Med Biol 41:10-6
|Pandey, Suresh; Venugopal, Archana; Kant, Ritu et al. (2014) ¹²?I-Epidepride: a PET radiotracer for extended imaging of dopamine D2/D3 receptors. Nucl Med Biol 41:426-31
|Garcia, Adriana; Venugopal, Archana; Pan, Min-Liang et al. (2014) Imaging pancreas in healthy and diabetic rodent model using [18F]fallypride positron emission tomography/computed tomography. Diabetes Technol Ther 16:640-3
|Baranwal, Aparna; Patel, Himika H; Mukherjee, Jogeshwar (2014) 18F-Fluorodeoxyglycosylamines: Maillard reaction of 18F-fluorodeoxyglucose with biological amines. J Labelled Comp Radiopharm 57:86-91
|Mirbolooki, M Reza; Constantinescu, Cristian C; Pan, Min-Liang et al. (2013) Targeting presynaptic norepinephrine transporter in brown adipose tissue: a novel imaging approach and potential treatment for diabetes and obesity. Synapse 67:79-93
|Upadhyay, Sanjeev Kumar; Eckel-Mahan, Kristin L; Mirbolooki, M Reza et al. (2013) Selective Kv1.3 channel blocker as therapeutic for obesity and insulin resistance. Proc Natl Acad Sci U S A 110:E2239-48


text:
How to write my essay on the topic java history
Discuss issues specific the Java port of Box2D
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How to write my essay on the topic java history
I am eleventh standard student. I am concentrating in computer science. So I get an essay on the topic java history. But I have no knowledge about the latest technology. And I don't know how to write an essay. So that reason my friends suggest me to use cheap essay writing service. If it good to use this service? He told me it is definitely works. please give me your opinion.
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Audience Wild Applause And Cheering
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An audience applauding and cheering wildly. Recorded in a medium size theatre from the stage's perspective with around 100 people aged 12-60 years old. Stereo recording made with matching mikes at an x/y recording pattern @ 24-bit/48khz.
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Linux_Magazine_DVD_Inlay.pdfFeb 28, 2008
more »
LINUX MAGAZINE DVDFeb 26, 2008
more »
Shuttleworth on Ubuntu 8.10 - Intrepid IbexFeb 21, 2008
Ubuntu is working on the next but one release, 8.10, codenamed Intrepid Ibex. Ubuntu promoter and Canonical CEO Mark Shuttleworth launched the next round of development in the traditional way by naming the product.more »
Centos 5.1 Live CDFeb 19, 2008
The makers of the free enterprise Linux, Centos, have released version 5.1, the latest version of their distribution on a Live CD.more »
Debian Update Introduces Security, Bans Adobe FlashFeb 18, 2008
The update Debian 4.0 alias Etch to 4.03r sees the free project mainly add security patches and remove the Adobe Flash plugin from the official repository.more »
Faster Package Management for Suse 11.0Feb 14, 2008
Suse developer Duncan Mac-Vicar gives a sneak preview of the next generation version of Novell's Zypper package manager in his blog.more »
Ubuntu Developer WeekFeb 14, 2008
The first Ubuntu Developer Week starts next Monday.more »
Opensuse 11: Alpha 2 with KDE 4Feb 12, 2008
The biggest change to the second alpha version of Opensuse 11 has to be the inclusion of KDE 4, which now replaces the older KDE version 3.5.8.more »
Issue 28: GIMP Handbook 4th Ed./Special Editions
Buy this issue as a PDF
Munich Plans to Ditch Linux and Go Back to Windows
A major setback for the Linux desktop.
Linux Kernel 4.10 Comes with New Security Features
Improved support for GPU in virtualization.
OpenSUSE Site Hacked
News site for the openSUSE community falls victim to a Wordpress exploit.
LibreOffice Goes Online with 5.3 Release
The source code is available online.
Microsoft Brings Clear Linux OS to Azure
One out of three virtual machines on Microsoft Azure Cloud run Linux.
ASUS Announces a Single-Board Computer
The form factor of the board makes it a drop-in replacement for Raspberry Pi.
Red Hat Releases RHEL 6.9 Beta
Makes it easier for customers to move workloads into container-centric applications.
SUSE Working on a New Operating System Called MicroOS
SUSE's answer to container-centric operating systems.
Biggest Kernel Release Ever
Linux 4.9 is the biggest release in terms of number of commits.
CentOS Linux 7 (1611) Released
The latest version of the official RHEL clone is here.


text:
Glencore Faces Yet Another Debt Challenge With Credit Due by Mayby
Add another looming problem to the list for Glencore Plc, the commodity group that's lost almost $45 billion in market value this year.
A quarter of the beleaguered firm's bonds and credit lines are due for refinancing by next May, compared with 9 percent for its peers, according to data compiled by Bloomberg. Glencore may have options for delaying the deadline for part of that $13.8 billion in lifeblood financing, but given that some of its debt is already trading like junk as the stock plummets, any bond refinancings will probably be pricey.
Shares of Glencore dropped 73 percent this year as a rout in commodities fueled by a slowdown in China's economic growth threatened to shrink the company's revenue as it attempts to manage its debt load. The company earlier in September announced a $10 billion debt-reduction program and cut its $30 billion of borrowings to protect its credit rating amid the commodity selloff.


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England have beaten Australia in the series 2-0. Eddie Jones is the coach of the England team and he is Australian. So the Australians are really angry at him for coaching the English Rugby team.
Some of the New Zealand supports are wanting to verse England because they have beat Wales in there series. Some of the English supports are saying because of Richie Mccaw departing now means that George Smith is the best no.7
Amazing wow!
All Blacks all and anyday
There will never be someone better that Richie MCcaw
This article sounds so bad it was like a kid wrote it😉
Wow I am really surprise that the England team has beaten Australia because Australia mainly always wins their game but just not against NZ and springbok.. But year 2 - 0 what a luck game plus their is no reason to get angry at Eddie Jones for coaching if I knew why they were angry at Eddie Jones then I would understand but right now.... I'm thinking that Australia is sore losers sorry for saying that but i think that it is true Australia is sore losers. THANK U 4 READING!!
I love rugby than my life
allblacks are the best
I have to addmit that I'm not a fan of sports at all. But NO! Why did the Auzzies lose England? I mean Australia is our closest neighbour. Why not cheer for them?
Awsome job boys
Double click on any word on the page or type a word:


text:
Title: Illusionist
Pairing: Zexion/Larxene
Rating: NC-17
Summary: Zexion walks into Larxene's room telling her that she's in one of his illusions. Despite the fact that she believes he's lying, she takes advantage of it.[ZexionLarxene,OneShot,] PWP,M/F,Lemon,MaleDom
Links: FanFiction.net: http://www.fanfiction.net/s/3212242/1/
Adultfanfiction.net: http://games.adultfanfiction.net/st
Author's notes: This story contains graphic lemon content. If you don't read mature fiction, you should leave now before you worry about what that means. (: I can't really say that some ages are restricted because, eh, kids at the age of twelve are probably reading this anyway, and I'm not supposed to be writing this myself, so I can only warn you all about the content.
FinaIity - -
IT WASN'T THE FACT that Zexion was in her room that made the rather annoyed Larxene growl and shove half of her head underneath her pillow. Rather, it was the fact that he had come at such an obscene hour in the night to pester her. It had become a rather normal thing for him now: coming into her room at night whenever he pleased. Always getting out of bed, having her mind fucked around with, and then waking up to discover that none of it had ever happened. Damned illusionist bastard.
He looked good enough to fuck, though—that much she'd admit. But only to herself; he was haughty enough as it was.
"Get the fuck out of my head. Do you have any idea what time it is?" the disgruntled blonde roared, shooting him an angry glare through the darkness that could melt lead as he stared her directly in the eye. "I'm not in the mood for those pointless mind games you play with me every night just so you can be amused for five minutes. Or however fucking long it really takes," she finished off, hands clawing at her comforter so that they wouldn't unconsciously go to his neck instead.
Ah, perhaps his persistence had succeeded in making her a bit peeved.
"This is no mind game," she heard him respond in the darkness, his voice low. Larxene then heard him shift, some part of his body briefly grazing against the wall from the sound she could distinguish: leather against marble.
"An illusion, then. Does that satisfy you?" she asked, one arm unconsciously waving about to accompany her words.
"Ah," he said dismissively, walking over to where she slept. Her frown deepened under the confines of her pillow.
"Thank you very much for avoiding my accusation. Your ignorance only proves that it is an illusion. Thank you for confirming it, Short Schemer," the Apathetic Princess stated mockingly, rolling over to face him. The only retort she recieved from the Tactician was a grunt. One of those grunts that he rarely issued out—which meant he was more than a little livid. "Short Schemer. I rather like that one," she serenaded on, grinning outrageously to herself. He could probably see her grinning, despite the lack of light.
It only made her grin stretch wider.
The long white comforter was pushed aside a bit as the mattress shifted and dipped in to accommodate her legs swinging down the side of the thick sleeping area. "Alright, then, Zexion. Have it your way; I'll play along with your little game of illusions," she said, voice low and domineering. Her hands went down towards her midsection to pull her nightgown over her legs from where it was bunched up at her hips. "I suppose I can go ahead and kill you if I please, then, can I not? After all, it is an illusion."
A smirk in the dark played on her lips.
She slid off the mattress with a sense of finality, gaining her balance slowly as she walked towards him.
One small hand violently lashed out to grab the collar of his robe, pulling him forward with incredible force. She deliberately pressed against him as vehemently as she could. Zexion audibly swallowed. Her lips were now mere millimeters away from his ear.
"…or I can fuck you if I please."
A little added emphasis never hurt anybody, now did it?
Well, it was about to.
The Sixth Order's lips parted so that a barely audible moan could slip through them as the Twelfth's moist tongue slipped out to graze his ear slowly before she proceeded to nip the cartilage hard.
The wall to her right was now behind her as she was slammed into it roughly before her lower lip was assaulted by the other's teeth harshly. Her face remained indifferent. Their roles reversed as the ravenous man attacked her. He didn't release the flesh until he drew a fair amount of blood.
"Mm, you're quite correct," he coincided, his voice almost sardonic.
Larxene quickly retreated the abused tissue into the safe confines of her mouth as she hissed.
"You have got some nerve waltzing into my room and beginning with your mindfuckery," she growled. The blonde's arms attempted to shift from their position on the wall, but to no avail. He was quite strong, and his psychic abilities made it more difficult to move with their added force. It was worth a try, though.
"Of course. 'Mind fuckery' is my most zealous interest, you see, as well as my illusions. They are a way to distort reality—to do whatever I please without causing permanent damage."
"So you just like to drag people around in your illusions so you can fuck around with them without having to pay the consequences?"
"I suppose," came the dry reply. "No need to make it sound like a misdemeanor."
"I hit the nail on the head and you know it."
"Whatever pleases you," he sarcastically retorted, smirking in the dark.
"Alright, then. The thought of you leaving pleases me greatly. Dissipate the illusion and leave," she said curtly. He ignored her and continued to press himself against her harder. One of his gloved hands went to her cheek.
She crossed her legs.
"It's an illusion, Larxene. Revel in it. Relish it. You can be uninhibited; release yourself," Zexion countered. The sexual tension in the air was practically a hum now. "Is there nothing you wish to do?"
"As a matter of fact, yes," the blonde answered silently before a dagger melted out of the space between her first two knuckles and was instantly in her grasp in the blink of an eye. Her eyes flashed to the man's collarbone before the dagger was sliced across the aforementioned body part. Dark blood began to trickle out of the clean cut. "Satisfied?"
The zipper of Zexion's coat was slowly pulled down by Larxene's pale hand, revealing more skin and the blood that had dripped down upon it. She cut off the trail of the leaking blood by placing the bright yellow end of her dagger on his skin. The blood pooled on the tip before it dripped down onto the white marble floor, leaving an ominous red circle.
"I'll have to clean that up later," she remarked.
The man showed no emotion; even as he grabbed the small dagger from her hand and pinned her to the wall, his face remained indifferent. Electricity hummed throughout both of their bodies as he placed said dagger against her neck. A shiver of complete pleasure ran down his back as he ran his fiery lips against the arrested area.
So that's why he had come.
"It's an illusion, Larxene. Revel in it. Relish it." The words revolved in her head like a marquee.
And so she would. None of it was real, after all.
"Alright, then. I'll revel in it. I'll fucking relish it," she bit out forcefully. Pink flesh had begun to replace the dark blood on his neck. She froze in place, hand in mid-air as her attempt to retrieve her dagger was foiled, for the weapon was upon her lips. A partial moment passed by before Zexion's lips replaced the weapon.
The elder felt the woman's lightning element pulsing through him in an even measure as he delved his tongue into the cavern of her mouth. She was pushed even more into the wall so that the man felt her ample chest pressing against his bare, bloody chest. Her nightgown now bore dark red streaks on it.
The pair's movement suddenly became dramatically heated as Zexion attempted to shift their position, or rather, change them completely. His first instinct was to rip her nightgown off and take her up against the wall until the screamed if her pride would allow, but that wouldn't fulfill his initial purpose of dragging things out long enough to drive her mad.
He was thrown out of his reverie when he found himself unconsciously pushing her farther up the wall. She had locked her legs around his slender waist and securely wrapped her arms around his neck.
Zexion's face was incredibly placid for such an intense moment, but Larxene's was something worthy of challenging. He ground his hips against her as her defenses went down. She let out a shaky breath that was strangely enticing for him and bit her lip.
Larxene could feel the thin straps of her nightgown being nudged off of her shoulder after Zexion's robe had dropped to the ground in a large black leather mound. Cool air now kissed her heated skin, causing her nipples to pucker, ache. The white nightgown fell on top of his robe in stark contrast. The woman was now only clad in the thin lace undergarment he was eager to tear off.
"Fucking hurry," she nearly yelled as he began to remove his gloves, her head being cradled by the hollow of his neck as she leaned down to lick the pulsing vein of the vertebrae.
"Patience," he growled. "Bitch." A shift in his attitude was evident.
She scoffed as he roughly threw her onto the mattress and began to remove his boots and bottoms. He was throwing things a safe distance away in the darkness to ensure their absence. Larxene had busied herself with the removal of the scrap of lace she called underwear. Both of the Nobodies' bare bodies were almost shining in the darkness. Ironic.
Zexion's mouth immediately clamped itself onto Larxene's left breast before she could open her mouth and complain, and she ached from the inside as she felt his body press itself against her between her thighs. Her hands clenched with a chunk of the cover sheet in them, the black mass becoming rumpled even more as his mouth licked a path up her breastbone before a trail of scorching kisses were pressed to her jawbone. His hands were both securely placed on either side of her shoulders as he propped his upper body up higher.
Larxene was driven into a frenzy since his agonizingly slow movements felt like they were consuming eons of time. She finally managed to open her eyes as he lifted himself up again to look at her face. Zexion looked positively delectable from what she could see as she looked up at him. His hidden eye was still blanketed by the shadows of the dark, but the section of layered hair that was constantly brushed onto his right half was now falling towards her, courtesy of the force of gravity.
His head swooped down before she had time to take in the sight for longer than a few seconds, and his mouth quickly claimed and ravaged hers. Welcoming his lust, his hardness, she met his tongue thrust for thrust, hands kneading his back.
Before the woman could blink or squeal, Zexion's hands had gotten a hold of her legs and pulled them upwards to rest them on his shoulders. The words "oh, fuck," were the last things to come out of her mouth before a vicious thrust of his hips had him pushing inside of her violently. Her mouth opened to let out a muffled gasp. He smirked outwardly as he saw her expression.
"I'm going to toss you well over the edge, Larxene," he growled, a low purr replacing his usual voice. Even when whispering, he possessed the most sensual voice; a rich, deep baritone that wrapped around her.
"I'm fucking taking you with me," she replied, her voice husky and a little strained from need. The blonde pushed herself against him. Zexion almost let out a groan from the delicious friction.
Zexion could feel her hunger, her need, and despite the fact that it was incredibly hard to persevere when he was about to begin ramming into the searing heat he was enveloped in, he was determined to make this just as agonizing for her. Larxene felt his hands anchor themselves at her hips.
He suddenly began to move, deep, deeper, lifting her up, pulling her down. Little by little, his rhythm began to quicken. Faster. Faster, still. He took her hungrily, brutally, pounding into her the way he'd wanted to all evening. A moan escaped his throat when she rotated her hips, taking him at a different angle. The woman beneath him could hardly think—all she could do was push against him in the quest for completion.
"Harder," she forcefully whispered, groaning as he surged forward again. Her passion-glazed mind was making her vision slightly hazy. Her hearing was limited by the loud sounds of his body ramming into her own, and her sense of smell was clouded by the scent of their bodies. She could still taste the lingering peppermint essence of Zexion's mouth. The only sharpened, heightened sense was her sense of touch, which was being sizzled by the feelings of electricity, sometimes literally, that their bodies were generating.
"Would you g— Oh!" She had opened her mouth once again to scream at him, but a moan tore from deep within her as she reached her sudden climax; it slammed into her, hard and sudden. The rest of her words died a quick death.
Molten sensations sent her spinning as she released all of the pent-up feelings.
The feeling of Larxene's inner alls clamping around him sent Zexion tumbling over the brink of extreme pleasure, just as Larxene had promised, before his pride gave way to an intense groan that almost sounded like he was in pain. Stars and lights flashed.
LARXENE'S EYES WERE TOSSED OPEN as the darkness pushed its way under her pale lids. She looked around her to register where she was before she recognized her bedroom. The room wasn't as bright as she would have liked, but things were visible enough for such and ungodly hour.
And then the memories of the night before flooded into her head with Zexion, the illusion, and the hot, rough, bed breaking hatese—
Even without the details, it was still an illusion. "Fucker," she mumbled.
She shifted a bit in her mattress and rolled over to make herself more comfortable.
Too bad the mental comfort was short lived as she saw a certain blue-silver-haired now pressed firmly against her, obviously unclothed as she saw the pale, well-muscled body begin to peek out from under the comforter. Zexion's hand wrapped around her waist roughly as he almost unconsciously leaned forward to bite her neck before his visible eye snapped open. "You shouldn't rise so angry in the mornings. It means the rest of us won't be having such a good time, either."
Larxene's eyes belatedly widened before she rolled on top of the surprised Nobody and straddled his hips.
So it wasn't an illusion. Big deal.
HAHA. I ttly had to do that whole "Larxene-wakes-up-with-a-really-warm-Zex
Clear. ~


text:
6 Pack Led Road Flares Bag Packed - Chinaprice: contact company for price
Led road flares is an essential piece of equipment for
police, firefighters, EMTs, rescue services, first
responders, members of emergency response teams and the
general public.
Led Road Flares Features:
16 super bright LEDs are visible up to ½ mileLighting covers
360 degree directionPush Button ON/ OFF Flash Selection
Button9 flashing patterns including SOS Rescue ( Morse
Code) Powerful magnet to attach to metal surfacesCorrosion &
crush proof, can be run over with any vehicle on the
roadWaterproof and submersible to 33 feet50 hours of use on
a full charge and hold a full charger for 6 monthsWorking
temp: - 40℃ to +100℃ or - 40℉ to +212℉ Size: 4.25" ( 11cm)
diameter X 1.25" ( 3.50cm) height
9 Flash Patterns Operating Time
Rotate 7 hours
Quad Flash 7 hours
Single Blink 50 hours
Alternating Blinks 7 hours
S. O. S. ( Morse Code) 12 hours
Steady on - high 4 hours
Steady on - low 30 hours
2- LED Flashlight 7 hours
4- LED Flashlight 5 hours
16 led road flares with CR123 battery120V/ 240V wall
charger12V/ 24V car chargerUSB charger
Led Road Flares Instruction:
Press ON/ OFF button to switch ONPush ON/ OFF button to select
from 9 different flash patternsPress ON/ OFF button and hold
down for 3 seconds to switch OFF
Led Road Flares Application:
Led Road flares will bring you safe and secure and can be
used as follows.
* The uses are limited only by your imagination. Customers
who need a reliable, ultra- rugged, ultra- bright light can
range from SCUBA divers, hikers, and cyclists .
* Search & rescue ( SAR) operations: tag areas and items;
personal safety light; emergency response teams
* Led road flares use as lantern in case of power failure,
earthquake, hurricane or other disaster
* Attach as a safety light for bicycles and motorcycles
* SCUBA diving / boating and marine operations
* Work zone safety: mount on cones or barricades
* led road flares seen in the dark. Be bright at night on the
road at a construction site or work site. Alert other
workers or passers- by that you need help and are under
duress when shouting does not help and want help from
emergency services.
LED Road Flares is an ideal signal light to identify Road
Hazards, Mark Detours, Underwater Repair Applications And
More and A great item to keep in your vehicle at all times
that can be used to signal for help or identify road hazards
and used for police, firefighters, EMTs, rescue services,
first responders, members of emergency response teams and
the general public and used in cars, trucks, boats, RVs,
semi- trucks, construction zones, and emergency response
Company Contact:
- Posted By: Winfys Industrial Limited
- Phone: 8613884483779
- Address: kakdh dehh, cixi, China
- Email:
- Website: http://www.winfys.com
Published date: September 14, 2014 -
- Business Description: WINFYS INDUSTRIAL LIMITED is a China Leading LED Power Flares ( Led Road
Flares ) manufacturer with the manufacturing capacity to provide low
prices, high quality and short lead time for LED Power Flares upon our
long policy of lower prices with high volume export. We actually
manufacture the led power flares in house which produces the wide
variety of 16 led power flares, 24 led power flares, rechargeable led
power flares and non rechargeable led power flares. Our manufacturing
facility is ISO 9001. We offer OEM service of rechargeable led power
flares, rechargeable led safety flares, rechargeable led emergency
flares, rechargeable led road flares, rechargeable led flares, led
traffic flares, led safety pucks light and led safety light.Our products
have been well sold in Europe, America, Australia, Middle East and South
Africa, etc.
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Info and Resources
Learn everything you need to know about this product.
Product Details
Learn more about what this product does and why you may need it.
Fits: 1989-1994 Mitsubishi Eclipse (Front)
The Monro-Matic Plus Strut is nitrogen gas charged strut at a great price.
You get a more comfortable ride and greater safety, These are good struts for your Mitsubishi Eclipse at a very economical price.
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What You Need to Know About Spine Pain
Spine pain has become a complaint that is common among the people of Seattle. Study suggests that four from every five people will build up a spinal challenge sooner or later in their lives. There's a large list of the causes of back pain and spine associated circumstances.
But typically these problems are connected with normal causes including muscles. A specific reason for back pain could be ailments including back herniated disc or degenerative disc disease. Most of the people, if they encounter some pain, go softly and feel that a painkiller will do away using the pain.
Interestingly, the extent of back pain, typically, does not have any connection with the amount of actual injury. Lower back spasms, for example, which results from simple back stress but will most likely, cause unbearable lower back pain. This can be extensive to the point that makes it actually difficult to stand or walk. Ironically, a big herniated disk can, in fact, be entirely painless.
This phenomenon can be very inaccurate. It is because a lot of people can simply find serious treatment if the back pain has turned into a large hassle and can dismiss slight back pain. This misinterpretation might be pricey particularly when the slight discomfort is just an indication of great injury inside the back.
When it is found back pain must, therefore, be maintained instantly. Anyone suffering must find a way of minimizing the ache within the initial phases. The majority of the back ailments just need therapeutic and medicinal relief techniques.
But first before engaging in any treatment solution, it is recommended to keep in touch with a physician. Spine doctors are specialists who have competency in back pain remedy. A spine physician can give people guidance to deal with and manage some behavioral styles in addition to their condition that they must stick to reduce potential problems.
You will find various ways of working with spine pain. A typical method is a physical therapy which has become effective on many clients. The use of ice or heat to relieve back pain can be employed. Problems that are worse require advanced means of analysis and cure.
Most of the people that are identified as having back ache find it too difficult to manage. Dealing with the pain may demand that individual to first acknowledge the things they are currently getting through. Take time to find out about the treatment and diagnosis.
Individuals also needs to look to get assistance from their family and friends to aid them to handle their problem. The process of coping with back pain is consequently both morally supported and medical. The skilled therapy ought to be enhanced from family and friends with help to assist the individual recover fully.
Source: pain management


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Kreg | SKU: T24969 | Model: PRS3100
Multi-Purpose Router Table Switch
Price: $34.95
Kreg PRS3100 - Multi-Purpose Router Table Switch
|Buy Now!
Add safety and convenience to your Precision Router Table with this incredibly handy power switch. This unique switch features a 2-Plug design which allows it to control two independent devices at once, Key-Lok which eliminates accidental power-on, and a long 8ft. heavy-duty 14 gauge power cord. Perfectly compatible with our Precision Router Table and Precision Benchtop Router Table. 15 amp, 120v.
Accessories and Related Items: View All
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Hunger at night
Hi doctor, I usually sleep at 12.30, 1 or 2. I am used to eat snacks at this time. Now the problem is if I am going to bed at 11 or 11.30. I m getting hungry at 12.30 or 1. I m not able to sleep as it is too much hunger. I want to avoid this problem. Can you please suggest a good remedy for this?
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Doctor Answers (2) on Hunger at night
Ms. Rekha Sachdev Pohani
9 yrs. of exp | Pune | Dietitian/Nutritionist
INR 250 for 24 hrsCHAT NOW
write me your weight height and diet details
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Dr. Swapan Banerjee
11 yrs. of exp | Kolkata | Dietitian/Nutritionist
93 %
INR 250 for 24 hrsCHAT NOW
Hi good to see your queries. I am not fully clear about your timings. Can u pl.write your daily lifestyles including meals, working etc.It will be better to advice u all by a mail id
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Explore Gardens Garden, Plants Gardens and more!
Explore related topics
Jardin de Castillon, près de Bayeux by tordouetspirit, via Flickr
THE jardin de mes rêves!!!
Carved stone heads with water flowing at Chateau de Courances
Jardín lavanda in Salamanca, Spain by Miguel Urquijo Rubio estudio de paisajismo / repinned on toby designs
André Le Nôtre, Jardins de Gourdon, c. 1679, France
In the old jewish quarter of Seville is the hotel Casas de la Juderia. It is made up from six or seven houses each with their own small courtyard garden. The Moorish influence can be seen in all the gardens. The houses have always been linked by underground passages that run through the basements of each house; and provided a means of escape during the days of persecution.
This planting season, think of the bees!
Haseley Court, Oxfordshire


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Via Spiga Amica Loafer
Sorry, this item is sold out!
Looks like you've got more shoe shopping to do - have fun!
Looks like you've got more shoe shopping to do - have fun!
Item # 371449
Slip on this shiny leather loafer from Via Spiga. The Amica is a professional flat that fits your sophisticated style!
- Box leather upper
- Cut-away lip with tassel detail
- Round moc toe
- ¾" block heel
- Rubber sole
- Imported
- View more Via Spiga
By: Millerly
Location: Denver, CO
September 20, 2016
Beautiful Slip on
"This is an elegant slip on with quality leather. I ordered it in black. It works well with casual and dressy wear. I love the fit and feel of the shoe!"
By: Ellaconti
Location: Houston, TX
September 09, 2016
Excellent shoes!
"I just love these shoes.They look great and feel great as well."
By: AADevon
Location: Michigan
August 08, 2016
high quality loafer
"Via Spiga never disappoints. These loafers are classic and very stylish. They are made of thick, quality leather with a high shine that is not patent. The inner lining is soft leather. It will take a little while to break in because of the thickness of the leather, so I have been wearing them inside for short periods of time. I have narrow feet, so I need a thin sock or an extra insole. I typically use a thin orthotic insole for arch support, and that fits very well - my heel does not slip out of the shoe.These feel about 1/4 size long. I have 7 1/2, and they are a little long, but not a full size 8. Thin socks or footies take up the extra space until they soften and mold to my feet."
By: AudreyWE
Location: Chicago
July 28, 2016
"These loafers are beautiful and very well made! The leather is beautiful and they are very sturdy. They are classic and will definitely last a long time. The toe bed is a bit narrow though so if you have wider feet, I would definitely try them in the store first."
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text: We visited 2 years ago and look forward to returning next week when we are back in the area. The beer is very cold and the owners Bob and Emily are fantastic, they even gave my friend and I a tour of their accommodation. Look forward to seeing them again next week and having the coldest beer in Port Vila


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My MS was just an icky feeling at 1st then it went to full blown all day nausea and then the vomiting started. Its horrible
My MS was just an icky feeling at 1st then it went to full blown all day nausea and then the vomiting started. Its horrible
Yep, like motion sickness for me too (although I fortunately didn't suffer too badly for too long). Is amplified when having actual car motion sickness too (which I am prone to when not pregnant).
I have occasional smells set me off to gag, but haven't ever vomited and generally eating a little food makes me feel better.
Agree that Ginger tablets are good for motion sickness feeling.
Nausea allllllllllllllll day and night long. Like one long hangover. I couldn't move, keep water down, anything it was horrible and lasted 5 & a half months until I could keep foo down properly. And then once or twice a morning when I woke up until i gave birth. It made me never want to be pregnant again.
Thats how mine was with my first preg, which turned to be a Boy. I just had that queezy sort of yukky feeling, but never threw up and it eased off in the 2nd trimester
This time, 8 years later, I am having extreme MS and am on medications for it, yet still quiet bed bound too... everyone says it will be a girl LOL
Pregnant for the first-time?
Not sure where to start? We can help!
Our Insider Programs for pregnancy first-timers will lead you step-by-step through the 14 Pregnancy Must Dos!


text: We're sorry, Poppy Print Dorothy Dress is no longer available Why not try one of these instead? Downton Abbey Flapper Embellished Dress by Gatsbylady London £85$145.87€101.87$108.91 free UK delivery Alpaca Pinafore Dress by Samantha Holmes £165$283.17€197.75$211.43 free UK delivery Petite Length 20s Inspired Flapper Embelli... by Gatsbylady London £85$145.87€101.87$108.91 free UK delivery Charisma Balloon Draping Dress by LALESTYLE £75$128.71€89.88$96.10 free UK delivery Pinch to zoom Poppy Print Dorothy Dress by Kiki's £69$118.41€82.69$88.41 This item is no longer available Favourite Favourite View your favourites sizesize (required)UK8UK10UK12UK14UK16size (required)UK8UK10UK12UK14UK16size (required)UK8UK10UK12UK14UK16size (required)UK8UK10UK12UK14UK16 we're sorry we're sorry, This item is no longer available buy a gift voucher related categories fashion > women's fashion > dresses > dresses by Kiki's Location: Derby, GB read seller's profile see seller's complete range more items from this seller Arm Candy Bag Of Tricks Vanity Case by Kiki's £12$20.59€14.38$15.37 Vintage Style Camera Watch Pendant Necklace by Kiki's £16$27.45€19.17$20.50 Silver Plated Message Bangle by Kiki's £15$25.74€17.97$19.22 Inspirational Friendship Wish Bracelets by Kiki's £3.95$6.77€4.73$5.06 Silver Plated Swallow Earrings by Kiki's £12$20.59€14.38$15.37 Daughter Silver Charm Bangle Bracelet by Kiki's £15$25.74€17.97$19.22 view all you may also like PRODUCT DETAILS DELIVERY RETURNS gift wrapping available ask seller a question save for later Emily and Fin Red and White Dorothy Dress The Dorothy Dress has had a face lift! This new dress has been nipped and tucked in all the right places for a better fit, and we approve! The Dorothy dress by Emily and fin is a Classic 40's inspired tea dress, with a button down front and a sweetheart neckline. The skirt is A-line and has concealed side pockets. The dress is waisted and comes with a fabric belt and pretty mid bell sleeves. This dress is fully lined. This red poppy print is our favourite pattern this season. Also available in black daisy print. made from: 100% viscose, fully lined. Machine washable at 30 degrees. dimensions: Length approx 98 cm. Sizes from UK 8 - UK 16 product code: 227394 This product is dispatched to you by Kiki's. You have 28 days, from receipt of cancellable goods, to notify the seller if you wish to cancel your order or exchange an item. Please note: goods that are personalised, bespoke or made-to-order to your specific requirements, perishable products and personal items sold with a hygiene seal (cosmetics, underwear) in instances where the seal is broken are non-refundable, unless faulty. Read more about our returns policy.Should you choose to return or exchange your order you will need to deliver the item(s) to the UK, where this seller is based. Kiki's's return policy Please see notonthehighstreet.com's returns policy.


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Hrithik Roshan divorce News
Hrithik Roshan all set to fly to Switzerland with kids!
Doting daddy Hrithik gives us major family vacation goals, doesn't he?
Hrithik Roshan has always been a hands on papa. Click here to read more
Sussanne Khan rubbishes rumours about marriage with Arjun Rampal!
She feels it is someone's fertile imagination at play here…
Superstar Hrithik Roshan's former wife Sussanne Khan has slammed reports that she is set to tie the knot with actor Arjun Rampal, saying she is a "proud" single mother. Click here to read more
Rumour Has It: Sussanne Khan to marry ex-husband Hrithik Roshan's close friend?
The Bollywood superstar ended his 14 year long marriage with his wife last year
Rumour mills are abuzz with the speculations that Hrithik's ex-wife Sussanne Khan set to remarry. Click here to read more
Hrithik Roshan's bond with ex-wife Susanne Khan's mother is still strong!
There doesn't seem to be any love lost between the two…
The divorce between Sussanne Khan and Hrithik Roshan had no bearing on the bond that Zarine Khan, mother of the décor expert, shares with the Bollywood actor. Click here to read more
Hrithik Roshan and Kangana Ranaut in a relationship?
The mystery man that Kangana admitted to being in a relationship with is none other than her Krrish 3 co-star
Two months ago in an interview to a daily, Kangana Ranaut had admitted that there is a man in her life. She said, " My love life is exciting. When you're in love, you kind of have to be sure about things that you make public. I hope it works out." However, the 27-year-old who has always been open about her relationship refused to reveal the name of the man in her life. Click here to read more
Divorced Hrithik Roshan should do action, dance, romantic, sci-fi and super hero movies in Hollywood, say fans!
After a lot of denials, the Bang Bang actor agrees to some international projects. Which sort of H-Town project would you like HR to feature in? Here's what his fans had to say…
Hrithik Roshan is a free man now. His divorce from Sussanne Khan has been finalised today. Bang Bang suffered a lot because of all the troubles that have been happening in HR's personal life (Divorce from Sussanne, Brain surgery, etc). But he has managed to give Click here to read more
Hrithik Roshan finally gets divorced from Sussanne Khan!
What will happen to their kids now? Read on to find out…
Fans of Hrithik Roshan and Sussanne Khan had been praying for the couple to get back together but Click here to read more
Hrithik Roshan has a dozen Hollywood scripts waiting in the pipeline!
After a lot of denials, the Krrish 3 actor agrees to some international projects. Which sort of H-Town project would you like HR to feature in…VOTE!!
Hrithik Roshan has been promoting his upcoming Bang Bang with a lot of fanfare. Amidst all the troubles that have been happening in his personal life (Divorce from Sussanne, Brain surgery, etc) he has managed to give the audience a superb cinematic experience and that is evident from the trailers and songs itself. However, people have been asking him about his Hollywood projects. Click here to read more
Hrithik Roshan and Sussanne Khan's Rs 400 crore alimony becomes butt of Twitter jokes!
This high profile Bollywood divorce has been making headlines for quite a few months now
Hrithik Roshan and Sussanne Khan's separation announcement didn't just have fans and media in a shock, but also Bollywood. While reports of trouble in their relationship were doing rounds since the Kites days, it's Sussanne blink and miss appearance at Rakesh Roshan's 64th birthday that got everybody talking. Finally Hrithik came out with an official statement announcing that his wife had decided to move on. The Bang Bang actor who was going through a lean phase, Click here to read more
Why does Hrithik Roshan travel in three cars?
The honey-eyed actor is currently shooting for his film Bang Bang and we hear he travels with a fleet of three cars. Is Hrithik obsessed with his automobiles? Not really…
Hrithik Roshan recently filed for a divorce and must be going through an emotional turmoil. In fact, the talented actor is physically drained too courtesy his not-so-great health. Click here to read more
Post separation from Hrithik Roshan, Sussanne gets custody of Hrehaan and Hridhaan!
Duggu and Sussanne were together for 17 years before they called it quits in December last year
Hrithik Roshan and Sussanne filed for divorce on April 30 at a Bandra family court and the decision was mutual. The couple went their separate ways last year and since then their two sons – Hrehaan and Hridhaan Click here to read more
Sussanne Khan retains Hrithik Roshan's surname even after separation!
This star wife certianly manages to surprise us each time
Sussanne Khan was a star wife until Hrithik Roshan announced his separation with her in an official statement. However, veteran actor Sanjay Khan's daughter in a recent statement said that she still holds her ex's surname. In a recent interview when she was quizzed about her name post parting ways with the Bang Bang actor, she quipped, "Sussanne Roshan, of course." Well, Ms Roshan manages to spring a surprise each time. Click here to read more
Does Hrithik Roshan need help to get over his divorce?
The Krrish 3 superhero has apparently hired a life coach with a questionable past to get over separation from Sussanne
Looks like Hrithik Roshan is seeking serious help to get over his separation with wifey Sussanne that grabbed headlines. The Greek God of Bollywood, we hear, has employed the services of a life coach with a questionable past, to tide over his recent separation from his wife. Click here to read more
Hrithik Roshan 40th birthday special: A sneak peek at the B-town superhero's life!
The Krrish 3 star had a mixed 2013 – a hit film, a broken marriage and major health issues! Will 40 be a better time for him? We think about it….
Hrithik Roshan turns a year older today. Last year the scene outside his residence in El Palazzo, Juhu, was bustling with activity. The Krrish 3 actor decided to celebrate his 39th birthday with the media and share his excitement and joy. What will he do this year when he hits the big four-oh? Click here to read more
A depressed looking Hrithik Roshan makes his first public appearance after split with Sussanne Khan, View pics!
The Krrish 3 star made his first public appearance this year after his much hyped split with wife Sussanne Roshan
Hrithik Roshan was a stark contrast to what his wife Sussanne Khan looked post their separation at her first public appearance. Sussanne had a starry store launch sans Hrithik and looked pretty in a little red dress, not to mention there were no signs of a broken marriage. Click here to read more


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This time she gets a new judge, has her bail and bond reduced, looks like she is off to stay her mums and is likely to have a case thrown out as she has passed her drug dependency course ?
Teenager Penelope Soto who flipped the bird at a Miami-Dade judge after laughing her way through a court hearing was back in the halls of justice Wednesday in a quieter, somber mood.
A day earlier, 18-year-old Soto appeared animated and agitated as she ticked off a judge during a bond hearing. After telling the judge "adios," shooting the bird and saying the f-word, Soto found herself in contempt of court and sentenced to 30 days in the slammer.
Soto appeared in drug court Wednesday, where a different judge, Jeffrey Rosinek, told her she would be released once she served the contempt sentence and that her case would be dismissed with the completion of a drug program.
She answered quest
By: Aussie
In: Other News, WTF
Tags: penelope, soto, judge, flip, bird, court, xanax,
Location: Miami, Florida, United States (load item map)
Marked as: featured
Views: 65864 | Comments: 439 | Votes: 6 | Favorites: 6 | Shared: 4193 | Updates: 0 | Times used in channels: 3
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Judge Richard Leon, US District Court, DC – master of the "Leave to File Denied"
Judge Arrested In Court For Treason By UK Citizens
Chief Judge of US Court, Los Angeles, Requested to Restore Integrity of the Courts in Litigations Involving Financial Institutions.
Greatest Courtroom Scenes Acted On The Silver Screen. - Part Three
UK Judge Arrested In Court For Treason
Woman Curses at Judge, flips him the finger
Cheecho Mertsaris Will Sex You Up
Complaint for Public Corruption,Racketeering Filed against Jacqueline Connor, Judge, LA Superior Court
Judge (JOKE) Judy
Police restraining teen in courtroom after being sentenced to Death
Girl who Flipped the Bird to the Judge Returns to Court Today
A word of caution .... do not flip off the judge


text:
Romania sees chance of another Eurobond issue in Sept-Nov
BUCHAREST Romania could issue another Eurobond in the third or fourth quarter before an expected national election, the finance ministry's deputy treasury chief said on Friday.
NEW YORK Technology companies spot signs of a pickup in demand but remain wary or skeptical that their sector has hit bottom, with many still cautious that the uptick merely reflects restocking by customers rather than a fundamental recovery in demand.
Speaking at the Reuters Global Technology Summit in New York on Monday, chief executives from an array of IT firms from Advanced Micro Devices Inc to Sybase Inc offered dour assessments of the economic environment.
Technology companies were stung this year by a steep drop in sales as consumers and businesses alike dialed back spending. Worldwide PC shipments fell 7.1 percent in the first three months of 2009, according to research firm IDC.
Suppliers responded by drastically cutting back on production, leaving inventories lean. Few analysts are willing to say that demand is truly recovering, given mounting job losses and an uncertain economy.
"In a situation like this particularly, a bottom is something you can really call when you're past it and looking down at it," said Advanced Micro Devices CEO Dirk Meyer.
"I'm hopeful things will stabilize and we'll see a resumption of growth in the back half of the year," he added.
Sybase foresees technology sector spending remaining tepid for at least a year and possibly until 2011.
"Nobody should run their business expecting the party is starting again," said CEO John Chen.
But Nvidia Corp CEO Jen-Hsun Huang sounded a discordant note, asserting that indeed a bottom has been reached, echoing comments made by Intel Corp, the world's largest chipmaker, last month.
"Demand appears to be growing again -- obviously from a lower base, but we're seeing demand growing nicely," Huang said. "We're actually seeing that there are spot shortages in the channel for several of our products."
Nvidia's dedicated graphics chips are featured in desktop PCs and more high-end notebooks. The company is also making a push into low-cost netbooks with its Ion product.
Huang said industry inventory levels were near historical lows after cutbacks in production over past quarters.
Sanford C. Bernstein analyst Toni Sacconaghi said it is too soon to tell when a recovery will take hold. He said the United States appears to have stabilized, while Europe looks weak.
"There's a question whether Europe is going to get worse before it gets better.
Other executives were simply uncertain.
Marvell Technology Group Ltd CEO Sehat Sutardja said it was difficult to tell if technology demand was recovering, noting it was hard to distinguish between temporary moves to replenish inventory and a true rebound.
"Nobody really knows whether real demand is sustainable, if the improvement in demand in the last few months were really sustainable, or if this is just an overreaction of people trying to replenish the inventory."
Marvell supplies a wide array of semiconductor products, including chips for hard disk drives for its largest customer, Western Digital. Apple Inc's iPhone and Research in Motion Ltd's BlackBerry also feature Marvell chips.
Britain's ARM Holdings Plc said chip sales had improved in the second quarter but said the rise was due to customers rebuilding inventory.
ARM's technology is used in more than 90 percent of the world's mobile phones, and products as diverse as set-top boxes and media players.
And finally, some executives, while tight-lipped on their predictions for the broader sector or economy, were convinced that their smaller peers were less than aware of the potential pitfalls of an uncertain year ahead.
Symantec CEO Enrique Salem said his company is no rush to acquire, as he expects valuations of private companies to fall over the next year.
"Private company expectations on valuation are still too high. We can afford to be patient."
(For summit blog: blogs.reuters.com/summits/)
(Reporting by Gabriel Madway; additional reporting by Jim Finkle, David Lawsky, Paul Sandle, Ritsuko Ando, Franklin Paul, Sinead Carew, Anupreeta Das; Editing by Edwin Chan, Richard Chang)
BUCHAREST Romania could issue another Eurobond in the third or fourth quarter before an expected national election, the finance ministry's deputy treasury chief said on Friday.
PRAGUE The Czech government prefers to use strong budget revenue to improve healthcare, education and defense rather than cut the budget deficit faster as the economy strengthens more than expected, Prime Minister Bohuslav Sobotka said on Friday.
PRAGUE The Czech government is aiming to make it easier for firms to bring in foreign workers to fill a labor shortage that industry leaders warn is becoming a barrier to growth, the industry minister told Reuters.