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APOBEC3B is a member of the cytidine deaminase gene family. Additionally we are shipping APOBEC3B Antibodies (44) and many more products for this protein.
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Data indicate that SIVmac239 Vif (show BTG1 Proteins) protein efficiently degrades human DNA cytosine deaminase APOBEC3B protein (huA3B).
Data show that restriction factor APOBEC3G (show APOBEC3G Proteins) (A3G) is susceptible to degradation by the HIV-1 Vif (show BTG1 Proteins) protein, whereas restriction factor APOBEC3B (A3B (show SGCB Proteins)) is resistant to Vif (show BTG1 Proteins).
APOBEC3B is required for regulation of gene expression by ERalpha (show ESR1 Proteins) and acts by causing C-to-U deamination at ERalpha (show ESR1 Proteins) binding regions.
These results suggest that functional potential of APOBEC3B and APOBEC3C (show APOBEC3C Proteins) involved in cancer mutagenesis is associated with estrogen receptor (show ESR1 Proteins) status.
The APOBEC3B deletion polymorphism was found to be associated with HBV, HCV, TTV (show EXT1 Proteins), and T. gondii co-infection in Indonesian HIV-infected individuals.
Germline variant and deletion polymorphism in APOBEC3B gene are not associated with breast cancer risk.
APOBEC3B expression was correlated with unfavorable prognosis in patients with gastric cancer.
APOBEC3B expression is an independent predictor of recurrence in patients with ccRCC, and the prognostic value is most prominent in those with low-risk disease.
report the first structures of the APOBEC3B catalytic domain in multiple crystal forms. These structures reveal a tightly closed active site conformation and suggest that substrate accessibility is regulated by adjacent flexible loops
APOBEC3B overexpression and Fhit-loss induced DNA damage are independent events that, when occurring together, result in a significantly increased frequency of APOBEC-induced mutations that drive cancer progression.
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control. A hybrid gene results from the deletion of approximately 29.5 kb of sequence between this gene, APOBEC3B, and the adjacent gene APOBEC3A. The breakpoints of the deletion are within the two genes, so the deletion allele is predicted to have the promoter and coding region of APOBEC3A, but the 3' UTR of APOBEC3B. Two transcript variants encoding different isoforms have been found for this gene.
apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3H
, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3B
, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3D
, probable DNA dC->dU-editing enzyme APOBEC-3B
, apolipoprotein B mRNA editing enzyme catalytic polypeptide-like 3B
, DNA dC->dU-editing enzyme APOBEC-3B
, cytidine deaminase
, phorbolin 2
, phorbolin 3
, phorbolin-1-related protein
, phorbolin-2/3
, apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like 3F
, DNA dC->dU-editing enzyme APOBEC3
, apolipoprotein B editing complex 3
, probable DNA dC->dU-editing enzyme APOBEC3


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The chance of all these properties coming together in the "just-right" proportions for our arrival is, objectively speaking, against all odds. As physicist Steven Weinberg puts it, "This is the one fine-tuning that seems to be extreme, far beyond what you could imagine just having to accept as a mere accident."
Indeed, it could lead the rationally inclined person to reasonably conclude that the whole thing is staged, something of a set-up job. But not so fast.
Making the improbable, inevitable
Turning rationality on its head, the philosophical naturalist starts with a bit of Sherlockian logic: "When you have eliminated the impossible, whatever remains, however improbable, must be the truth." Then, after defining the "impossible" as anything supra-natural, he concludes that life is not improbable, it's inevitable—our existence is Exhibit "A." Clever.
His favored explanation as to how is the "multiverse," a supercosmos consisting of an infinite number of universes where anything can and does happen, somewhere. As he spins it:
Out of the pre-cosmic nothingness, a blast of energy suddenly appeared, setting off an explosion of cosmic "bubbles" (think what happens when you pop the top on a dropped bottle of soda). By a singular event called "inflation" (think anti-gravity), each bubble ballooned at a rate faster than the speed of light into a separate universe with its own unique physics.
In short, our Big Bang was one of many "bangs" produced from nothing by nothing, resulting in a multiplication of universes guaranteeing the actualization of every imaginable and unimaginable outcome, including the appearance of beings who can dream all this stuff up.
Problems galore
The tale has undeniable flair, but with problems aplenty, not the least of which is an air of contrivance that oozes desperation.
Technically speaking, the theory includes exceptions to thermodynamics (mass-energy conservation) and special relativity (the inviolability of light speed); phenomena (inflation and other universes) that have never been observed or replicated; and untestability, such that if another world did exist with its own unique set of physical parameters, it would be undetectable with instruments constrained by the distinctive parameters of our universe.
Collectively, these novel devices and exceptions violate Occam's Razor, a cardinal principle of science that holds that when various solutions are offered to a problem, the simplest is the preferred. What's more, for a scientific theory, the multiverse makes no predictions, has no technological cash value, and holds no promise for the betterment of man or the planet.
But what should raise even the least skeptical eyebrow is that the multiverse is not derived from evidence or data but, rather, on the necessity of its story-tellers to avoid considering the Impossible. As cosmologist Bernard Carr warned his colleagues, "If there is only one universe you might have to have a fine-tuner." And, just in case they missed his point, Carr added, "If you don't want God, you'd better have a multiverse." Check.
Carr tipped the hand on the "dirty little secret" of cosmology: The object is not to follow the evidence wherever it leads, but to follow our wishes and boldly go, hoping they're so. And this, promoted by folks who are proud to say that, unlike believers in the Impossible, their beliefs are not based on faith or wish-fulfillment, but hard evidence.
Sci-fact or sci-fi
Those of more sober mind will sense there is more of metaphysics than physics going on here. Indeed, the notion that nothing became everything, instantly, is magic, not science; that it happened (or is happening) ad infinitum is more befitting sci-fi than sci-fact.
Science writer and journalist John Horgan agrees. "Multiverse theories aren't theories," Horgan writes, "they're science fictions, theologies, works of the imagination unconstrained by evidence."
David Gross, Harvard particle physicist and multiverse skeptic, urges his colleagues to not quit on fundamental science by settling for theories that can explain anything. As he well knows, a theory in which anything is possible, is a theory that includes the possibility that some of those unsettling philosophical and theological conclusions might also be true.
Then there's Steven Weinberg again, who in a theoretical physics conference at Stanford learned that British cosmologist Martin Rees was so confident in the multiverse that he would he bet his dog's life on the theory and that inflationary theorist Andrei Linde would bet his own life on it. To which, Weinberg quipped, "As for me, I have just enough confidence about the multiverse to bet the lives of both Andrei Linde and Martin Rees's dog."
But perhaps the harshest critic of inflation and the multiverse is Paul Steinhardt. Since receiving the 2002 Dirac Medal in theoretical physics for his work on inflationary theory, Steinhardt has turned on the theories.
Steinhardt explained, "For the last 400 years, most people would say the key thing that distinguishes science from non-science is that scientific ideas have to be subject to tests. Some people are nowadays thinking, no, that doesn't necessarily have to be the case. That's a mega-issue [for me]." He went on to say that these theories are unfalsifiable and can be made to fit any possible set of experimental observations. And that's a "deal-breaker."
Last best hope
For most theorists, however, the multiverse is the last best hope to keep the flames of the Enlightenment burning. The very notion that the Impossible could be true is an existential threat to science that could end discovery and technological progress, hurling civilization back into a new Dark Age of superstition, ignorance, and fear. Serious stuff.
But the whole question of why we're here is not a scientific question; it's a theological one. Whether the explanation is God, the multiverse, or some yet to be discovered mechanism of cosmic Darwinism, it will always be tentative and unprovable, because no matter how reasonable and robust the theory, there is no way of knowing that it's in fact the way it happened. Thus, our favored explanation will always be a matter of faith, faith in our presuppositions of how the world is.
At the same time, the answer has no effect on the scientific enterprise or our ability to study and harness nature for the good of nature and man.
To the contrary, our ability to detect, measure, and analyze the light spectra from a distant quasar is independent of whether the star was produced from the Big Bang or the command of God. The study of the human genome—its functions and similarity with other species—is independent of whether it is a product of common descent or common design. Advances in medical science do not depend on whether microevolution is a phenomenon of mud-to-man Darwinism or was front-loaded by an intelligent Designer. The recent confirmation of the Higgs boson (the "God Particle") didn't hang on whether the Higgs was produced by a random fluctuation of the quantum field or from a Divine pronouncement. No, all of these things and more are there to be discovered and studied irrespective of their ultimate origin.
But while the question of origins has no bearing on how we conduct our science, it does have an implication on how we should conduct our lives.
In a world created by matter and motion, there is no right and wrong, no duty, no oughts, only existence; every person is free to pursue his notion of the good life in a way that seems right to him. But if we are here by Divine intention and action, we are not morally autonomous happenstances; we're creations, beings whose very design implies purpose and who, one day, will stand before the Impossible, and shudder.
Therein lies the rub.
Image courtesy of the Smithsonian Institute via NPR.
Regis Nicoll is a freelance writer and a BreakPoint Centurion. Serving as a men's ministry leader and worldview teacher in his community, Regis publishes a free weekly commentary to stimulate thought on current issues from a Christian perspective. To be placed on this free e-mail distribution list, e-mail him at firstname.lastname@example.com.


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Life style changes in diet, exercise and stress reduction are the premise of healthy living and healthy looks. What we think and what we eat are at the foundation of how we look. What we take time to enjoy in the beauty around us not only gives greater meaning to our life, it adds to the beauty that is reflected in our appearance. Busy schedules and rushing adds years to our appearance and causes a decline in organ function. It is critically important to take time out to relax and indulge ourselves at times.
Editor's note: The following is the first of a series of monthly columns about historical incidents from Trimble County's past. The column title is taken from the ripples that still roll across the remains of the old Milton dike long submerged in the Ohio River. Many of the long-forgotten events of our past still cast shadows over our way of life today and create ripples that continue to lap at the shores of the river of life upon which we are all mariners.
South Oldham defeated Trimble County 4-1 in girls' tennis on March 28. Trimble's No. 1 singles player Kasi Fogle defeated South Oldham's Anna Townsend, 6-0, 6-2. No. 2 singles Kalee Cook was defeated by South Oldham's Sarah Hawes, 1-6, 0-6. Trimble's No. 3 singles, Cierra Harmon, was defeated by Mason Maylong, 0-6, 0-6.
Records set at Shelby
Trimble County's track team had a "very impressive night" in the March 29 Shelby County All-Comers Meet in Shelbyville, according to Coach Jeff Vincent. New school records were set by Olivia Cooley in the Long Jump and Kelsie Courtney in the High Jump.
Team members registered 19 personal best performances, claimed four first place finishes and scored 35 top eight finishes.
Individual results for the Raiders are as follows.
"It was simply inexcusable what went down today!"
Trimble County Coach Frank Ragland's displeasure with his team's performance was quite evident throughout Saturday's baseball outing at Southwestern in Hanover. The Raiders led briefly but were stunned 14-7 in the Rebels' season opener.
"We didn't hit the ball. We didn't field the ball. We didn't throw the ball. We didn't catch the ball. It's as simple as that," Ragland said following the game.
Trimble County Coach Walter McHargue lamented that his team couldn't hold border rival Carroll County after the Lady Raiders let a three-run advantage evaporate and fell 8-7 in Carrollton Friday.
Carroll lost to Trimble three times last year, twice during the regular season and during the All-A tournament, by a combined run total of 24-5.
Trimble opened the game with a 1-0 lead in the first inning, but Carroll roared out of the gate in the bottom of the third to take a 4-1 lead.
Trimble County Lady Raiders Coach Walter McHargue hopes his young softball team can quickly mature into a well-oiled machine and win some ballgames.
In an interview following Trimble's third loss in four outings McHargue said his team has two returning seniors—Raegan Black and Jana Dunlap—from last year's team that finished the season with a 12-17 record.
Returning students at each of the 16 colleges in the Kentucky Community and Technical College System (KCTCS) will receive guaranteed tuition, with no rate increase, for the 2011-12 academic year, if they enrolled during the fall 2010 or spring 2011 semesters. These students are eligible for a guaranteed tuition rate of $130 per credit hour, the same rate they paid during the 2010-11 academic year.
The KCTCS Board of Regents approved the guaranteed tuition rate during their June 2010 board meeting to enhance student retention and credential completion rates.
Kathy Beckner Woody has recieved her Ph.D. in Chemistry from Georgia Institute of Technology.
Kathy is a 2001 Trimble County High School graduate and graduated from University of Kentucky in 2005 with a Bachelor of Science degree in Chemistry. During her time at Georgia Tech, she received several national honors, including a fellowship from the American Chemical Society Organic Chemistry Division.
Copyright © 2017
The Trimble Banner is your source for local news, sports, events, and information in Trimble County, KY and the surrounding area.


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Employer costs for employee compensation in metropolitan areas, March 2009
September 28, 2009
In March 2009, employer costs for employee compensation in private industry averaged $27.46 per hour nationwide. Among 15 metropolitan areas, however, the costs ranged from $25.42 in Miami to $38.28 in San Jose-San Francisco.
Among the localities with high hourly compensation costs are San Jose-San Francisco ($38.28), Boston ($35.60), and New York ($35.45). At the other extreme, with relatively low hourly compensation costs, are areas such as Miami ($25.42) and Phoenix ($26.01).
To illustrate the range of cost differences between localities, compensation costs are about 50 percent higher in San Jose-San Francisco than they are in Miami.
These data are from the Employment Cost Trends program. To learn more, see "BLS Introduces New Employer Costs for Employee Compensation Data for Private Industry Workers in 15 Metropolitan Areas," in Compensation and Working Conditions Online, September 2009.
Bureau of Labor Statistics, U.S. Department of Labor, The Economics Daily, Employer costs for employee compensation in metropolitan areas, March 2009 on the Internet at https://www.bls.gov/opub/ted/2009/ted_20090928.htm (visited January 19, 2017).
Recent editions of Spotlight on Statistics
Workplace injuries and illnesses and employer costs for workers' compensation
Workplace injury and illness data and the costs to employers for workers' compensation in natural resources, construction, and maintenance occupations.
A look at the future of the U.S. labor force to 2060
Projected long-term trends in the growth, size, and composition of the labor force.
Union membership in the United States
Historical trends in union membership among employed wage and salary workers; union membership by a variety of demographic characteristics.
A look at healthcare spending, employment, pay, benefits, and prices
Spending on healthcare, current and projected employment in the industry, employer-provided healthcare benefits, healthcare prices, and pay for workers in healthcare occupations.
Self-employment in the United States
Trends in self-employment by various demographic and socioeconomic characteristics, including both the unincorporated and the incorporated self-employed, as well as data on paid employees who work for the self-employed.


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|Literary Criticism and Postmodernism
"Inasmuch as many have undertaken to compile a narrative of the things that have been accomplished among us, just as those who from the beginning were eyewitnesses and ministers of the word have delivered them to us, it seemed good to me also, having followed all things closely for some time past, to write an orderly account for you, most excellent Theophilus, that you may have certainty concerning the things you have been taught." (Luke 1:1-4)
Words Strain and Crack
Thus wrote T. S. Eliot in Burnt Norton V from The Four Quartets. Eliot describes the breakdown of meaning that occurs as words and their meaning die under the limitation of time. In these lines, especially if one reads them out loud and in the context of the entire poem, the breakdown of meaning hits us in a way that is startling, disconcerting, and palpable.
Eliot's Four Quartets, published in 1944, were masterful because they vividly depict so many of the struggles, challenges and agonies characteristic of the late modern (or early postmodern) period in which he wrote. Precisely because of this, the hope of redemption held out by Eliot at the end of The Four Quartets is all the more powerful.
The agonizing words of Eliot's poem are a good lead-in to what I want to discuss in this article, which is the Postmodern approach to language in general and literary texts in particular. (If you do not already know what Postmodernism is, then you may want to read my brief overview of Postmodernism or buy Gene Veith's book Postmodern Times.)
Deconstructing texts
The very existence of texts presupposes that communication is possible. Words have meaning, and while the meaning of words can often be misunderstood or change with time, the possibility of genuine, objective communication remains a reality.
At least, that was the prevailing assumption until the 20th century. Though all generalizations have exceptions, by and large people just took it for granted that it was possible to read and understand texts, even as they knew it was also possible to misread and misunderstand texts.
All this began to change in the mid-1900s, when literally thousands of intellectuals began deconstructing the legitimacy of the text as a vehicle of communication. This deconstruction did not happen overnight, but was the result of at least three important factors. We will explore each of these three factors in turn, before looking at the implication this had for literary criticism.
All readings are misreading: the influence of German hermeneutics
Ever since Martin Luther, Germans have retained a keen interest in hermeneutics, but in the 20th century the questions they were asking started to shift. Instead of asking about the appropriate way to interpret a text, they began exploring whether the notion of a 'correct interpretation' was even a viable concept. Do texts even communicate, let alone offer us objective insight, into the mind of the author?
One important thinker in this process was the German philosopher Hans-Georg Gadamer (1900 –2002). In his book A Primer on Postmodernism, Stanley Grenz summarizes Gadamer's approach to hermeneutics:
"…the goal of hermeneutics is not to discover the 'one meaning' of the text. The meaning of the text is not that strictly circumscribed: the limits of a text's meaning are not confined to just the author's intent or the reader's understanding. In fact, we can never claim that any one interpretation is correct 'in itself.'"
While Gadamer denied that his view led to relativism, or that it excluded the possibility of genuine communication, many others would say exactly that. After all, if we can never claim that a given interpretation of a text is correct, if we can never say that a text's meaning is limited to what the writer may have meant, then can a text mean anything? And if a text can mean anything, is there another sense in which it also means nothing? Are all interpretations which claim to have grasped the author's meaning therefore false? If so, are 'readings' actually misreadings?
These were only some of the unsettling questions raised in 20th-century Germany.
Nothing outside the text: the influence of French philosophy
French philosophers have always taken an interest in the relationship between words and reality. During the 20th century, French philosophers began asking whether there was any correspondence between language and the reality language describes. I am over-simplifying things here, but many philosophers began pointing out that because the meaning of any word is anchored by its definition, and because a definition is only as good as the other words which make it up, the entire network of verbal signs collapses in self-referential circularity. But if the entire network of verbal signs is self-referential, then any term has a potentially infinite semantic range. Put another way, any word can drift anywhere in the ocean of meaning, a notion known as 'free play.'
The implication these theories had for literary criticism was realized by Jacques Derrida (1930– 2004) who famously remarked that "there is nothing outside the text." In his discussion of deconstructionism in A Glossary of Literary Terms M.H. Abrams explains the significance of Derrida's oft-quoted remark:
"Like all Derrida's key terms and statements, this has multiple significations; but a primary significance is that one cannot get beyond the sequence of verbal signs to anything that stands outside of, and independent of, the language system that constitutes a text – for example its referents, or else the intention of its speaker or writer to express a determinate signification."
Put in layman's terms, what Abrams is saying is that for French deconstructionists like Derrida, there was a radical separation between our words and the things we think the words refer to. We are thus trapped in what Jean-François Lyotard (1924–1998) called "an infinite plurality of language games" since we cannot assume that our words actually refer to an independent reality that is 'out there.' All language thus collapses into radical subjectivity.
Shattering all metanarratives: the influence of American social sciences
During the mid to late 20th century, American public life began to be characterized by numerous groups all competing for public attention. Each group wanted to carve out a bigger share in the political, cultural and educational systems that made up America's national life.
Whether the groups in question were feminists, Christian activists, racial minorities, gay activists, environmentalists, etc., it seemed that the best each of these groups could do was to talk past each other.
Whereas at one time all Americans participated in common national meta-narratives that gave a shared reference point, as the 20th century wore on these various groups came to be characterized only by their own mini-narratives, rendering futile even the possibility of inner-communication.
Isolated in our own groups, all hope of intelligible interaction across the ideological divide becomes lost. What this leaves us with is only "Shrieking voices/Scolding, mocking, or merely chattering."
American theorists explained this phenomenon by saying that it is impossible to transcend the limitations of our own interpretative communities. The only story that is worth any of us telling – indeed the only story that any of us can ever tell - is either my own personal story or that of my group. Sociologists went even further and pointed out that when each of us tell our own stories, we cannot do it in reference to any larger narratives, because (and this is key) there are no larger stories that are true for everyone.
This being the case, we can only see ourselves in reference to ourselves. To try to make sense of our world with reference to any larger framework is invariably to impinge on someone else's reality.
American social scientists thus replaced universal metanarratives with small local or individual narratives. All the big stories are broken up into billions of little stories with no relation to each other. This emphasized the multiplicity of valid theoretical standpoints and the relativity of our beliefs. Jean-Francois Lyotard described this well in The Postmodern Condition when he suggested that we have moved "from the muffled majesty of grand narratives to the splintering autonomy of micronarratives."
To put all of this more crudely: what is true for you need not be true for me. Living under the canopy of the postmodern metanarrative that there are no metanarratives (yes, I know), we are freed from the constraints of consistency. We no longer have to relate our lives to any larger meaning or outside purpose. David Wells grasped this mood in his book Losing Our Virtue, when he wrote
"It means that people have nowhere to stand cognitively in the world, no way to get their bearings, that life's experiences fall like pieces of confetti with no relationship to each other. Life is made up of a multitude of separate experiences that are without interconnections or meaning."
Dispensing with authorial intent
Postmodernism has brought us to a position where many academics truly believe that the meaning of a text remains completely inaccessible to the reader. Literary criticism is thus plunged into an abyss of relativity since, to quote again from Abrams, "the meaning of any text remains radically 'open' to contradictory readings."
Not only does it become impossible ever to know what the author truly meant, but it becomes presumptuous even to try. Even in those cases where the author has clearly explained his meaning, we cannot bridge the inaccessible chasm between his mind and ours. All we find is isolated words that echo back to us our own stories, like someone projecting his own emotions onto Mona Lisa's smile.
You might expect that these postmodern theories would have brought the entire discipline of literary criticism to a standstill. After all, what is the point of reading, let alone commenting about a book if the author's meaning is inaccessible to us as readers? In practice, however, these postmodern theories did quite the opposite of bringing literary criticism to a standstill. Indeed, throughout the late 20th century, the field of literary criticism has exploded into an almost endless amount of different directions.
If you think about it, this is not surprising. If a text can have no determinate meaning (since no one can really understand what an author means anyway), then the floodgates are opened for going back and reinterpreting the canon of Western literature in new and creative ways. Since the meaning of a text is no longer constrained by authorial intent, interpretation becomes unbounded.
Thus, throughout the 20th and 21st century we have witnessed Jungian interpretations of Homer's Odyssey, Marxist interpretations of Plato's Republic, poststructuralist interpretations of the New Testament, post-9/11 readings of Milton's Samson Agonistes, socialist interpretations of the American constitution, etc., ad infinitum.
Did Homer actually intend for the journey of Odysseus to be an allegory of Jungian archetypes? Did Saint Paul really intend that his words to the Corinthians would not be de-coded until the 21st century? Were the framers of the American Constitution really proto-Marxists without realizing it?
After Postmodernism, the answer to these questions is that it doesn't matter. Since postmodern literary criticism does not have to be anchored to the intent of the writer, there is no longer a court of appeal by which we may adjudicate between the vista of competing interpretations that now accompany any single text.
Unhinged from authorial intent, the science of literary criticism is collapsing into merely another instrument for furthering political agendas and ideologies.
Implications for the Church
As Bible-believing Christians, we know that genuine communication is possible. When God gave us His Word, He was not giving us a text that was inaccessible to us.
When Luke opened his gospel, he said he was writing "that you may have certainty concerning the things you have been taught." (Luke 1:4) Similarly, when John was writing his gospel he said "I write these things to you who believe in the name of the Son of God that you may know that you have eternal life." (1 John 5:13) If the meaning of the Biblical text was inaccessible to us, it is hard to see how certainty and knowledge could derive from it. Though the Holy Spirit's assistance we are able to truly understand what the Biblical authors meant, even though we cannot always understand it completely. Words do not "strain/crack and sometimes break, under the burden..."
But if this is true, then (contrary to the claims of Postmodern theorists), when we read the Bible it is our responsibility to constantly ask, "what did the original writers [ultimately, God Himself] intend for this to mean?" This forces us to be attentive to questions of context, genre, language and history.
Sadly, many Christians have succumbed to a Postmodern approach to scripture. You may have been at a Bible study before where it is the custom to go around the room sharing what this passage means to me. Having been influenced by Postmodernism, we think that any interpretation of a passage is just as legitimate as any other, while the question of what Moses, Luke or Paul may have actually meant is completely neglected.
At the same time, however, we need to be careful not to fall into the opposite ditch. The Holy Spirit is free to apply scripture in a variety of ways. In the New Testament we see some of the writers taking verses from the Old Testament and applying them in new and creative ways. Similarly, sometimes the Holy Spirit will take a verse and apply it uniquely to our situation. But there is always an important difference between interpretation and application.
In this regard, what is true of scripture is true of other literary texts. Using Milton's play Samson Agonistes to give us insight into religiously motivated violence in the post 9/11 world is one thing; claiming that doing this helps to clarify the actual meaning of the text is quite another. The meaning of a text is always and only what the author meant by it. That is why there can only ever be one correct interpretation of a text, even though there may be any number of legitimate applications.
In a future article I hope to continue to explore the implications this has for us as Christians.
Next steps
Check it out for yourself: Ask some of your friends – Christian and non-Christian – whether there are any truths that are true for everyone in all places and times. If they say yes, ask for some examples. If they say no, ask how they know that. Do you think postmodernism has affected the way people think about their lives?
For further insight into this topic, read Robin's article "Solzhenitsyn Against Postmodernism." Also consider buying Gene Veith's book Postmodern Times from our online store.


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Authentic Street Signs Pittsburgh Pirates Avenue Sign
Product Information:
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DSHS HIV/STD Program
Post Office Box 149347, MC 1873Austin, Texas 78714
Phone: (512) 533-3000
E-mail the HIV/STD Program
E-mail data requests to HIV/STD Program - This email can be used to request data and statistics on HIV, TB, and STDs in Texas. It cannot be used to get treatment or infection history for individuals, or to request information on programs and services. Please do not include any personal, identifying health information in your email such as HIV status, Date of Birth, Social Security Number, etc.
For treatment/testing history, please contact your local Health Department.
For information on HIV testing and services available to Persons Living with HIV and AIDS, please contact your local HIV services organization.
The Texas HIV Medication Program (THMP) provides medications for the treatment of HIV and its related complications for low-income Texans. To qualify for medications, potential clients who meet eligibility criteria complete an application for assistance. Once approved, a client receives medications at an assigned pharmacy in their community.
To learn more about the THMP and find out if you are eligible, see the
Frequently Asked Questions. You can apply for the program by downloading and completing the
client application. Be sure and review the specific "application instructions" when completing the application. The application and its instructions are located in the
document section of the THMP website. If you have more questions or need assistance completing your application, call the THMP toll free at 1 (800) 255-1090.
The THMP is the official AIDS Drug Assistance Program (ADAP) for the State of Texas. The THMP has been in existence since 1987 and provides medications approved by the Food and Drug Administration (FDA) for the treatment of illnesses caused by the human immunodeficiency virus (HIV) and other opportunistic infections in HIV-infected individuals as prescribed by their doctor. THMP also operates the Texas HIV State Pharmaceutical Assistance Program (SPAP) which helps HIV-positive individuals that do not qualify for the full Low Income Subsidy (extra help) with their out-of-pocket costs associated with Medicare Part D prescription drug plans, including co-payments, deductibles, coinsurance, and during the coverage gap (the "donut hole").
THMP is now offering access to direct-acting antiviral Hepatitis C medications (starting December 1, 2016). To apply, complete and submit the Hepatitis C Medical Certification Form (PDF : 129 kb).
The combination therapy medications Evotaz and Prezcobix were both added to the Texas HIV Medication Program formulary on March 6, 2015. Both drugs were recently approved by the Food and Drug Administration to treat HIV-1 infection. Evotaz is an oral tablet that combines the protease inhibitor Reyataz (atazanavir) with the CYP3A inhibitor Tybost (cobicistat), which increases the amount of atazanavir in the blood to control HIV infection. Prezcobix is an oral tablet that combines the protease inhibitor Prezista (darunavir) with the CYP3A inhibitor Tybost (cobicistat), which increases the amount of darunavir in the blood to control HIV infection. The THMP expects to have both medications in stock and available for clients as of March 9, 2015. The updated Medical Certification Form is available for download on the
documents page. Should you have any questions please call the THMP at 1-800-255-1090.
Tybost (cobicistat) was added to the Texas HIV Medication Program (THMP) formulary on February 2, 2015. Tybost was recently approved by the Food and Drug Administration as a CYP3A inhibitor indicated to increase systemic exposure of Reyataz (atazanavir) or Prezista (darunavir) in combination with other antiretroviral agents in the treatment of HIV-1 infection. The THMP will have the medication in stock and available for clients as of February 5, 2015. The updated Medical Certification Form is available for download on the
documents page. Should you have any questions please call the THMP at 1-800-255-1090.
It's always a good idea to make plans in advance for your medical needs during hurricane season in Texas. As evidenced in recent years, the hardship experienced during an evacuation from the impending storm can be stressful enough without the added complication of interrupting your antiretroviral dosing regimen and the subsequent lapse in therapy. With that in mind, the THMP has prepared an informational guide to assist you in planning for what to have on hand ready to take with you should an evacuation occur, along with a form you can fill out summarizing the crucial medical information you'll need to have available:
Hurricane Preparedness Info for THMP Clients (PDF : 29 kb)
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Aaron Lee Tasjan Band
Ashley Pond.
Alt-rock, outlaw country from Ohio.
Honey Island Swamp Band
Ashley Pond.
Rock Gumbo from New Orleans. LA Monitor Night.
Igor & the Red Elvises
Ashley Pond.
Los Alamos' favorite rock 'n roll band returns. LA Daily Post Night.
Greg Abate Quartet
At Ashley Pond.
America bebop from Rhode Island. Member of Rhode Island's Jazz Hall of Fame. KRSN Night.


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A Tablescape we can all be Thankful for!
October 25, 2013 by Core'dinator
Filed under Core Blog, Tim Holtz
I know we have been giving you all sorts of Halloween Inspiration but today we are switching gears to something to be thankful for!Some truly gorgeous pieces from Designer Jennifer Edwardson that will make your Thanksgiving truly memorable. Thanksgiving in Canada was a few weeks ago but due to our three blog swaps, we are a bit behind on the blog. You can never complain about not enough inspiration around here, that's for sure!
And Jennifer created this Thankful Frame using TONS of Tim Holtz Kraft-Core!
You need to see these close-ups!
We have a HUGE giveaway for you! How exciting is this?
All you need to do is LIKE both Core'dinations and Couture Creations on Facebook (giving our friends over there shout out would be nice, too 😉 and then click HERE to enter to win! That's it! We are giving away FOUR prizes of $50 FULL of products from both companies. You don't want to miss this!
Handmade Paper Roses with Clare Buswell
September 19, 2013 by Ellen
Filed under Core Blog, May Arts Ribbon, Tim Holtz, Tim Holtz & Ranger Adirondack Collection, Tim Holtz & Ranger Collection, Tim Holtz & Ranger Distress collection
If this was Facebook we would need a LOVE button for this post!
Graphic45 Vintage Love with Clare Buswell
July 18, 2013 by Ellen
Filed under Core Blog, Graphic 45, May Arts Ribbon
You are not going to want to miss these beauties! Designer Clare Buswell is designing Vintage style for us today with some Graphic45 papers and Signature Series Cardstock. Sit back and enjoy…it's gorgeous!


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1. Stand Design and Construction
A. Official Stand Contractor
San Yau Expo Pte Ltd has been appointed as the Official Contractor for Sports & Fitness Asia2016. For contact person, please refer to our Official Contractors listing.
Exhibitors having Raw Space stand area may employ a contractor of his choice to construct and install any stands they may require. The name of the contractor must be given to the Event Secretariat by completing the Technical Form. Stand facilities listed are subjected to change at the discretion of the Event Secretariat without prior notice.
If exhibitors do not want any item in the standard stand package, they must accept that the cost of the package will not change and there will be no compensation or replacement with other equipment.
Additional furniture and electrical items can be rented from the Official Stand Contractor. Please place your order by completing the respective forms and returning these by the stipulated deadline.
No drilling, screw, paint, nail or fixture of any kind are allowed to be affixed onto partitions, floor or ceiling. Exhibitors are liable for any damages to their stands, fixture & fittings and the Exhibition venue, where caused by them or by any person or persons employed or engaged on their behalf. The cost of repair of any damages will be assessed by the Official Stand Contractor and charged accordingly to the exhibitor. The Event Secretariat, together with Venue Representative, will inspect the hall before and after the event.
B. Customised Stands arranged by Exhibitors with Official / 3rd Party Contractors
Exhibitors having Special Design stands can use the service of the Official Stand Contractor appointed by the Event Secretariat to undertake the job as this will facilitate convenient installation. Otherwise, exhibitors are required to obtain consent from the Event Secretariat before any of their own contractors are allowed to carry work on-site. The Event Secretariat reserves the right to reject any contractor and design they deem inappropriate. Each stand must have its own panels and it is not permitted to use neighboring panels. If any panel is higher than the one behind it, acceptable decoration or material must cover the back of the panel.The exhibitor may employ a contractor of his choice to construct and install any stands they may
require. The name of the contractor must be given to the Event Secretariat by completing the Technical Form.
Failure to obtain written approval can result in costly alterations onsite such as when designs or installations violate fire and safety, stand height and boundary or any space contract rules and regulations. When the Exhibitors appointed contractor is not the Official Stand Contractor, this contractor will be required to lodge with the Official Contractor, a refundable deposit of $500 per stand.
This is to ensure that the rules and regulations are abided by and to cover any damages arising directly from any infringement. This is without prejudice to any additional claims the Event Secretariat may have on the contractor if the damages exceed the deposit.
C. Construction height
The max permitted stand height is 5m. Any stand structure, exhibit or display about 2.44m high must be at least one metre away from the neighbouring partition wall. Suspended items or banners from the hall ceiling, and any special stand construction has to be approved by the Event Secretariat.
D. Building Material / Dangerous Materials
No temporary gas, petrol or highly inflammable substances are allowed in the halls. No false ceiling will be approved. All pressure vessels or equipment must conform to safety standards and regulations.
Approval for its use is required.
2. Hall Specification
A. Floor Loading Capacity
The floor load capacity of the Exhibition hall is 17.5KN/sqm. Special arrangements including the provision of a steel base plate may be required for any exhibit exceeding these limits. The Event Secretariat's delivery schedule for heavy and large exhibits must be strictly adhered to.
B. Power Supply & Lighting
The Event Secretariat will provide general lighting in the exhibition hall during show time only. The standard electrical current supply available for use is 220V. Exhibitors requiring different voltages/frequency or special connections to equipment must arrange directly with the appointed Contractor.
All electrical installation and equipment must comply with government regulations.
For safety reasons, all electrical installation work at the exhibition must be carried out solely by the Event Secretariat's appointed Contractor. The Event Secretariat reserves the right to cut off power supply in case of improper connections. Multi plugs and gangways are strictly not allowed.
All sockets are for machine use only and not for lighting. For safety reasons, please use one socket for one machine only.
C. General Cleaning
The Event Secretariat will provide general cleaning service of the show area. This only includes cleaning of carpet/flooring and rubbish disposal before the exhibition opens in the morning and after the exhibition closes in the evening. It excludes cleaning of exhibits and displays. It is the responsibility of the exhibitor to maintain the cleanliness of his booth at all times.
D. Removal of Waste
During the set-up and tear-down period, passageways in the exhibition hall must not be obstructed with packing materials, construction materials or debris. Contractors building Special Design booths or booth interiors are responsible for removing their own debris from the site all the materials from their client's booth. Should they not do so; the deposit paid will be used to pay for removal by the official cleaning contractor.
Exhibitors are requested to place their debris in the aisle, from where it will be removed by the cleaners at the end of each show day. The Event Secretariat reserves the right to charge exhibitors for the cost of removal of excessive packing materials and discarded crates or cartons.
E. Industrial Gas Demonstration & Fire Protection
Exhibitors, who, because of the nature of their exhibits, require specific fire precaution, must make arrangements at their own cost for provision of such equipment/service. Exhibitors must not bring in or use at the exhibition site any dangerous or hazardous goods and equipment such as poisonous gas, fuel, kerosene, noxious materials, inflammables and equipment using such inflammable materials as gas stoves and electric stoves without written consent of the Event
Secretariat. Even when the consent is given, adequate precautionary measures must be taken by exhibitors at all times. Exhibitors are also not allowed to carry out any fire hazardous operation/work.
All safety precautions must be taken by the contractor or the exhibitor to protect the public against any danger of fire outbreak. The Venue Representatives may require on-site inspection to ensure maximum fire safety.
F. Storage
Direct arrangements should be made with an appointed official freight forwarder. Otherwise, exhibitors must arrange for their cartons and cases to be transported back to their own premises. Exhibitors are not to store such items within the exhibition halls.
The organiser reserves the right to remove/dispose of any carton, cases and/or packing materials left in the exhibition halls. Any cost incurred will be borne by the exhibitor.
3. Film, Audio / Visual & Product Demonstration
Audio visual equipment may be provided by the exhibitor or hired from the official AV supplier. When in operation, audio visual equipment must not disturb visitors or exhibitors with excessive sound/noise. The Event Secretariat reserves the right to discontinue any audio visual presentation which in their opinion is disruptive to the event. When a high level of noise or other objectionable factors are involved, demonstrations may only take place at timing stipulated by the Event Secretariat, who reserves the rights to disallow a demonstration at any time.
No photography or video recording is allowed in the exhibition hall unless written approval is obtained from the Event Secretariat.
4. Lucky Draw Application
Any promotional activity involving the above will need a permit from:
Lucky Draw Application
Gambling Suppression Branch/ CID
Blk C Police Cantonment Complex
391 New Bridge Road Singapore 088762
Attn: Lucky Draw Officer
Tel: (65) 6435 8220
Fax: (65) 6220 7142
5. Insurance
General Insurance will be covered and handled by the Event Secretariat. However it is the responsibility of each exhibitor to arrange insurance coverage for their own exhibits during the exhibition.
All exhibitors must arrange at their own cost "all-risk" insurance coverage from origin country up to their exhibition booth including exhibition period and return to domicile. Exhibitors must ensure that they are fully covered by insurance and take out public liability and comprehensive protection.
Exhibitors are also responsible for making good any loss or damage to any item which they have rented or hired from the official contractors/suppliers. Though the Event Secretariat maintain the security surveillance at all times, exhibitors are reminded that goods/exhibits will still, nevertheless, be at risk, especially during the final day of the show.
Please ensure your stand, especially personal and valuable property, portable and rented items, are not left unattended at any time before, during and after the show. Exhibitors are reminded that small, portable and valuable items are most at risk after the exhibition closes each day. Therefore, exhibitors are advised to keep these items safely stored each day before leaving the exhibition area.
If your exhibits are very valuable or sensitive and you wish to hire security personnel to attend to your stand exclusively for off show hours, please contact the Event Secretariat.
6. General Security
The Event Secretariat will provide general security round the clock. Exhibitors and their staff will not be allowed to enter the exhibition area after official hours. All personnel in the exhibition area must wear identification badges. Exhibitor badges and temporary passes could be collected at the Registration Counter on-site.
7. Booth Operation
No business activity shall be conducted by the exhibitor and his co-participant outside their booth boundaries such as distribution of promotional material outside their booths. Activities which will inconvenience or disturb the conduct of the business session, will not be allowed.
Without special permission from the Event Secretariat, delivery of exhibits cannot be taken into the booth once the show has officially opened, nor removed from the booth before closure of the event. If exhibitors wish to remove any display item from the show area, a written request must be submitted to the Event Secretariat for approval.
Exhibitors must give proper consideration to the conditions under which their equipment will be demonstrated. Precautions must be taken for protection of the public.
Exhibitors are strongly encouraged to remove valuable and portable exhibits from the exhibition hall as soon as possible after 1800hrs on the final day of the show. Fire & Safety regulations require that no goods or packing materials may be stored in access areas behind or between booths. Exhibitors should design proper storage areas with adequate access within their own booth.
The exhibitor and his staff shall be responsible for any damages to the structure, floor, walls, pillars and any part of the Exhibition Hall, the Property of the Event Secretariat, and other Exhibitors due to the transport, removal of exhibits, refuse and/or decoration works.
Aisle ways indicated on the floor plan must be kept clear of all exhibition goods or decoration materials in order to facilitate flow of traffic. Exhibitors & Contractors must clear items not for display purpose (e.g. containers, packing items) the day before the show period according to the schedule. The Exhibitors will have to reimburse the Event Secretariat for the cost of removing such articles from their booth if they fail to do so.
Cleaning of paint containers or any other dirty items in the washroom is prohibited.
8. Working Exhibit
Working machinery or moving equipment must be fitted with safety devices when the machines are in operation. These safety devices may be removed only when the machinery or equipment are not in operation and are disconnected from the source of electrical power. All pressure vessels and machinery or equipment under pressure must conform to local safety standards and regulations.
Working machines must be place at a relatively safe distance from visitors. Use of safety guard is strongly recommended. Any machinery or apparatus displayed in the Exhibition Hall shall only be demonstrated within the Exhibition Booth, operated by qualified persons and shall not be left running without proper supervision of such persons. No motors, engines or power driven machinery may be used without adequate protection taken out by the Exhibitor against risk of fire.
9. Intellectual Property Rights
The Event Secretariat has the right to request Exhibitors to remove exhibits which are alleged to violate intellectual property rights. Any possible legal consequence resulting from such breech will have to be borne by the exhibitors concerned.
10. Regulatory Authorities
Where applicable, the above rules and regulations are additional to rules and directions set by the Regulatory Authorities. All exhibitors and their contractors must abide by the code of practices set by the relevant Regulatory Authorities.
11. Food and Beverages (F&B)
No external F & B suppliers/caterers are allowed to supply or cater any form of food and beverage in the exhibition hall. Singapore Expo provides an extensive range of F & B services to suit any event. Please approach the centre for all F & B requirements.
12. Force Majeure
In the event that the event is postponed, shortened, extended or cancelled due to any cause whatsoever outside or beyond the control of the Event Secretariat and Organizer, the Event Secretariat and Organizer shall not be held responsible for any losses incurred by the exhibitor directly or indirectly, attributable to the elements of nature force majeure or orders and directives imposed by any government authority. Under such circumstances, the money paid by the exhibitor or any part thereof, is refundable at the sole discretion of the Event Secretariat.
13. Unforeseen Occurrences
In the event of any unforeseen occurrences or not stated in these Rules & Regulations, the decision of the Event Secretariat shall be final.


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iHerb Customer Reviews
Savings of: $29.50 (59% off)
Controlled Labs, Green Bulge, Creatine Matrix
Posted by Reviewer3072575 on Oct 07, 2011
Good product, it works! Improved workout, to take just before training..
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Amazing stuff...
Posted by Reviewer2756092 on Mar 04, 2013
Using it 2nd times.It takes about 2weeks till it really kicks off but worth to wait...My bench went up at least with 20%.No water retention,no bloating.Recovery happens faster and a nice feeling of over-all well being can be experienced.Enhanced mood and energized non-training days...Tried many other Creatine formulas but nothing can beat Green Bulge... : ))
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Proposed teams for 3.org
We have created more than a half-dozen teams for the 3.org initiative, based on various discussions, ideas, and proposals. As a general disclaimer, these may evolve over the next few days.
API Reference. This team will build a comprehesive API reference based on inline documentation, and integrated closely with the handbooks. Lead: Nacin. Members: duck_, koopersmith, jorbin, mikeschinkel, benbalter.
Handbooks. This team will edit a series of handbooks, with the ultimate goal of one each for users, multisite admins, plugin developers, theme developers, and core contributors. Lead: Jane. Editors: Lisa Sabin-Wilson, Andrea Rennick, Doug Provencio, Aaron Jorbin, Andrew Nacin, and others TBA.
bbPress as a Plugin. This team will concentrate on creating a bbPress plugin for WordPress. Lead: JJJ. Member: PeteMall.
We're going to create a few teams to focus on the plugins directory. These teams may overlap and in some instances work together, but it is important to primarily work in small teams with manageable, defined scope. More about our general goals in this blog post.
Plugin Directory: Support and Management. Develop tools enabling plugin authors to better support their plugins, and for better administrative management. Lead: Mark Jaquith. Members: beaulebens, Dougal, WDS-Brad, Glenn Ansley.
Plugin Directory: Community. Improve user interaction with the directory, such as user reviews, adoption, comments. Lead: Peter. Members: filosofo, Dan Cole, Brian Layman, Michael Torbert.
Plugin Directory: Core Integration. Improve installer, upgrades, compatibility reports, api.wordpress.org. Lead: Ryan. Members: TBD..
UI Working Group: Will assist other teams. Lead: Jane. Members: JohnONolan, TECannon, Dremeda, MT, Kevin Conboy.
We have identified two additional projects that would need teams to proceed:
i18n Projects. Improving the management of localized plugins, and also providing better tools for localized communities.
Plugin Directory: Stats. SVN notifications, improvements to Trac, better stats for plugin developers (and aggregate, public download stats).
Quick hits for what's not on here and why. Ideas forum: It's a GSoC project by Justin Shreve. Themes directory: We hope lessons learned in the plugins directory projects can be carried over to the themes directory. Forums: We believe the plugins directory and the bbPress projects will offer incremental improvements to the forums. Codex: See API reference and handbooks. Profiles: We've realized without studying this well and developing a solid direction, a profiles project could flop. We're going to go ahead with these projects and discuss profiles in the near future. Site content and design: We'll get there.
If you're not on here, we're sorry. We either omitted you accidentally, or weren't sure what you want to commit to, or didn't know enough about you to offer you an assignment. Please let us know where you'd like to be involved in the comments (links to your website, portfolio, etc would be useful). Just note that some of these teams are already pretty much at their maximum, as we want to them to be agile pirate/ninja teams. But we don't want to leave anyone out who wants to enlist their skills and feels they can contribute.


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Prostate cancer is one of the most commonly diagnosed cancers in men in the United States and a major cause of cancer morbidity and mortality. The Johns Hopkins Prostate Cancer SPORE is focused on reducing prostate cancer incidence and mortality by translating new laboratory research discoveries into improvements in prostate cancer screening, detection, diagnosis, prevention, and treatment. Thus far, new prostate cancer biomarkers, inherited prostate cancer susceptibility genes, new approaches to prostate cancer immunotherapy, prostate-specific antigen-selective replication-restricted cytolytic adenoviruses, endothelin A receptor antagonists, prostate cancer-specific pro-drugs, and dietary approaches to prostate cancer prevention have all been introduced into clinical trials or population validation studies. This competitive renewal proposal contains six new Translational Research Projects, three Core Resources, two Career Development Projects, and two Developmental Research Projects. Research Project #1 aims to combine aptamer-targeted radiosensitizing interfering RNAs and radiation therapy, Project #2 considers the contributions of prostate-specific antigen itself to prostate cancer progression, Project #3 tests the enhancement of prostate cancer immunotherapy achievable with antibodies against auto-immune checkpoint regulators, Project #4 targets the development of histone deacetylase inhibitors as anti-angiogenic agents for prostate cancer, Project #5 pursues the discovery and validation of epigenetic biomarkers for prostate cancer progression, and Project #6 drives the development of new serum biomarkers for prostate cancer. Each of the Projects directs new scientific findings or insights toward human clinical trials or to population studies;each also features Co-Principal Investigators managing effective multidisciplinary translational research teams. The Research Projects are supported by an Administrative Core (A), which also manages inter-SPORE collaborations, a Tissue Archive Core (B), and a Biostatistics and Epidemiology Core (C).
|Regter, Sietze; Hedayati, Mohammad; Zhang, Yonggang et al. (2014) Androgen withdrawal fails to induce detectable tissue hypoxia in the rat prostate. Prostate 74:805-10
|Ku, ShengYu; Lasorsa, Elena; Adelaiye, Remi et al. (2014) Inhibition of Hsp90 augments docetaxel therapy in castrate resistant prostate cancer. PLoS One 9:e103680
|Chalfin, Heather J; Frank, Steven M; Feng, Zhaoyong et al. (2014) Allogeneic versus autologous blood transfusion and survival after radical prostatectomy. Transfusion 54:2168-74
|Bhatnagar, Akrita; Wang, Yuchuan; Mease, Ronnie C et al. (2014) AEG-1 promoter-mediated imaging of prostate cancer. Cancer Res 74:5772-81
|Brennen, W Nathaniel; Rosen, D Marc; Chaux, Alcides et al. (2014) Pharmacokinetics and toxicology of a fibroblast activation protein (FAP)-activated prodrug in murine xenograft models of human cancer. Prostate 74:1308-19
|Paller, C J; Olatoye, D; Xie, S et al. (2014) The effect of the frequency and duration of PSA measurement on PSA doubling time calculations in men with biochemically recurrent prostate cancer. Prostate Cancer Prostatic Dis 17:28-33
|Durham, Nicholas M; Nirschl, Christopher J; Jackson, Christopher M et al. (2014) Lymphocyte Activation Gene 3 (LAG-3) modulates the ability of CD4 T-cells to be suppressed in vivo. PLoS One 9:e109080
|Gurel, Bora; Lucia, M Scott; Thompson Jr, Ian M et al. (2014) Chronic inflammation in benign prostate tissue is associated with high-grade prostate cancer in the placebo arm of the prostate cancer prevention trial. Cancer Epidemiol Biomarkers Prev 23:847-56
|Lutz, Eric R; Wu, Annie A; Bigelow, Elaine et al. (2014) Immunotherapy converts nonimmunogenic pancreatic tumors into immunogenic foci of immune regulation. Cancer Immunol Res 2:616-31
|Zheng, Qizhi; Peskoe, Sarah B; Ribas, Judit et al. (2014) Investigation of miR-21, miR-141, and miR-221 expression levels in prostate adenocarcinoma for associated risk of recurrence after radical prostatectomy. Prostate 74:1655-62
Showing the most recent 10 out of 579 publications


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Check in from 2:00 PM / Check out prior to 11:00 AM
Loch Ness Country House Hotel at Dunain Park: Find photos, reviews, information, amenities and compare prices for 4 stars hotels in Inverness, United Kingdom.
Situated less than a 10-minute stroll from Inverness Bus Station, Loch Ness Country House Hotel at Dunain Park offers guests a convenient base while in Inverness. It is close to Eastgate Shopping Centre, eateries and shops.
Hotel description
This chic hotel offers meeting rooms, a hair salon and an express check-in and check-out feature. Helpful and professional staff are available 24-hours a day. Just moments from nearby bars and clubs, this 4-star hotel also allows guests to explore the local nightlife.
Loch Ness Country House has 15 traditional rooms that are equipped with a variety of essential amenities to ensure guests have an enjoyable stay. There are also honeymoon suites available.
Those staying at the property can start the day with breakfast every morning at Loch Ness Country House Hotel before heading off to explore the local region. For those with day trips planned, the hotel provides packed lunches on request.
Loch Ness Country House Hotel at Dunain Park is close to Inverness's well-known attractions, with Inverness Castle, the Eden Court Theatre and River Ness just a 10-minute stroll away. Additionally, a range of tourist attractions are within easy reach.
Hotel features
Room Service, Restaurant, Bar / Lounge, Coffee / Tea Maker, Hair Dryer, TV, Shower
Business Center, 24 Hour Reception, Dry Cleaning, Safe-Deposit Box, Meeting Rooms, Laundry service, Photocopier, Desk, Luggage Storage, Designated Smoking Area, Express Check-In/Check-Out, Self Laundry
Golf Course, Garden
Internet Connection (wireless)
Bathrobes, Packed Lunches, Shoe Shine
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Pre-College Summer Sustainability Program
The School of Global Environmental Sustainability Pre-College Summer Sustainability Program offers high school students an unparalleled opportunity to work with professors, professionals, and graduate students from some of the top ranked university programs and departments in the world.
Come hike through Rocky Mountain National Park, raft down the Cache la Poudre River, and explore research in action at Colorado State University. Each day of the Program will add another piece to the sustainability puzzle whether it is out among the prairie dogs on the Shortgrass Steppe, high in the Rocky Mountains investigating wildfire and ecosystem health, or discovering local food initiatives in Old Town Fort Collins. This program empowers you with a foundational understanding of sustainability that increases your capacity to think of creative solutions, broaden your global perspectives and be involved in your community.
No matter where your interests lie, whether it be sustainable green building, preservation of natural areas, climate change, sustainable local communities or global collaboration, this program will help you connect the dots between ecosystems, our society, and the economy.
Mentorship is a core goal of the Pre-College Summer Sustainability Program. Get a jumpstart on your college career and join us this summer!
Our eight-day summer residential program highlights six focal areas of sustainability:
- Climate Change and Energy
- Food Security
- Environmental Institutions and Governance
- Sustainable Communities
- Land and Water Resources
- Biodiversity Conservation and Management
Students will have the chance to interact regularly with Colorado State University professors and graduate students working in each of the six focal areas. The experiental learning approach will give students hands-on experience in the field. Academic curriculum will be brought to life at some of Northern Colorado's most exciting locations!
Where Does it Take Place?
The Program is based at the Colorado State University campus in Fort Collins, Colorado.
Field trips will visit:
- Rocky Mountain National Park
- The Cache la Poudre River
- Shortgrass Steppe Research Information Center
- CSU's Atmospheric Science Campus
- Old Town Fort Collins
- And more!
Life on Campus
Students will be immersed in the rich Rocky Mountain campus environment at Colorado State University with access to the Student Recreation Center and evening activities in the historic Old Town of Fort Collins. Students will be housed on campus in the Corbett Residence Hall which features suite style rooms for a taste of college living.
Who Should Join Us?
We encourage local, national, and international high school students with a passion for the environment and an interest in sustainability to apply! The typical student for the program will be entering their junior or senior year in high school in the fall of 2016. However, high school students outside of this age range are still welcome to apply. This program will expose participants to a wide range of social, economic, and environmental perspectives on sustainability.
This program is for you if:
- You are creative
- You are interested in hands-on learning about diverse ecosystems
- You want to find innovative solutions to complex problems
- You enjoy nature
- You want to strengthen leadership skills
- You are interested in working across academic disciplines
- You are a global thinker
- You want to learn new skills and have fun while doing it!
Who do I Contact?
For additional information and questions about the program, contact the The School of Global Environmental Sustainability home of the Pre-College Summer Sustainability Program at firstname.lastname@example.com or call (970) 491-1423.


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Microsoft Accessibility CD Set Materials Available Online
Microsoft Accessibility CD Sets are no longer available for shipment. However, all materials found on the CD sets are available online for immediate use. The chart below provides links to the online resources.
|CD Set Contents
|Resources Available Online
|Accessibility Resources CD
|Demo CD for Accessibility in Windows Vista
|Demo CD for Accessibility in Windows XP
Windows XP
Microsoft ended support for Windows XP on April 8, 2014. Technical assistance for Windows XP is no longer available, including automatic updates that help protect your PC. Learn what this means for you and how to stay protected.


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Press Releases
Pompeo: IAEA Report Proves Iran Lied about Its Nuclear Program
December 2, 2015
Pompeo: IAEA Report Proves Iran Lied about Its Nuclear Program
Says IAEA report fails to provide thorough and conclusive review of Iran's nuclear weapons related activities
WASHINGTON, D.C. – Congressman Mike Pompeo (R-Kan.) today issued the following statement on the International Atomic Energy Agency's (IAEA) release of its "Final Assessment on Past and Present Outstanding Issues regarding Iran's Nuclear Programme."
"The IAEA report on Iran's nuclear program finally proves that Iran lied about never having attempted to develop nuclear weapons and that the Iranian Supreme Leader's fatwa against nuclear weapons development is a fraud," Pompeo said. "The IAEA's report is dangerously incomplete and should be rejected by the IAEA Board of Governors for failing to fulfill its stated purpose of being a 'final assessment' of the possible military dimensions (PMDs) of Iran's nuclear program. Understanding Iran's past weaponization work is absolutely integral to verifying that this regime has not resumed its nuclear weapons program. The IAEA must not close the book on Iran's past nuclear weapons related activities until a thorough and conclusive report has been completed. This document doesn't even come close to accomplishing that basic task."
Pompeo serves on the House Permanent Select Committee on Intelligence. He is an Army veteran and graduate of West Point.
Tags: Foreign Policy


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