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What is Bromium Endpoint Protection?
Bromium Endpoint Protection, a module of Bromium Advanced Endpoint Security, transforms endpoint security with a revolutionary new architecture that focuses on protection through CPU-enforced isolation. Bromium Endpoint Protection protects desktops and laptops without requiring signatures or updates. It defeats and automatically discards malware, eliminating the need for costly remediation. Bromium Endpoint Protection empowers users to access the information they need without putting your enterprise at risk. Because it is transparent to users, it enhances their productivity and offers them the flexibility to work anywhere — from home, hotels, airports or cafes — without risk of compromise.
How It Works
Bromium Endpoint Protection is built on the Bromium Microvisor, a Xen-based, security-focused hypervisor designed to automatically isolate each vulnerable user task, such as visiting a website, opening a document, or accessing a USB drive. Malware entering a micro-VM cannot modify the operating system or gain access to local or enterprise data or network infrastructure. Whenever an isolated task attempts to access files, networks, devices or the clipboard, or to interact with the user, the hardware interrupts execution and passes control to the Microvisor, which applies task-specific policies on a strictly need-to-know basis. The power of isolation is also applied to unknown file-based executables, ensuring that malicious executables cannot run on the protected endpoint.
Why You Need It
Traditional security solutions rely on detection of malicious content and often fail to block attacks that use unknown zero-day exploits or advanced persistent threats (APTs). Bromium uses isolation to stop known and unknown attacks without disrupting the user experience. In addition, Bromium streamlines IT processes, reducing and even eliminating:
- compromises on endpoints
- costly remediation and reimaging
- the need for urgent security-related patching
- the noise and cost of security alerts and the wasted effort of chasing false positives
Organizations improve their security while lowering their costs and increasing productivity.


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Adelphi University is proud to announce that Doreen Downs Miller, M.B.A. '86, will receive an honorary doctorate of humane letters at Adelphi University's 117th Commencement Ceremony. The event will take place on May 19, 2013 at 10:00 a.m. at Nassau Veterans Memorial Coliseum, 1255 Hempstead Turnpike, Uniondale, NY.
Doreen Downs Miller earned her M.B.A. at Adelphi in 1986. She is a parent educator specializing in early childhood development, temperament and the influence of attachment relationships on developmental outcomes. She is presently affiliated with the Adelphi University Institute for Parenting as a parent educator and Instructor of a post-masters certificate program in parent education and parent guidance. Ms. Miller is also a founding member of the Institute for Parenting and serves on the Advisory Board. She is formerly affiliated with the NYU Child Study Center Parenting Institute, the California Parenting Institute in Santa Rosa, CA, and was an instructor at NYU Steinhardt School of Education. Additionally, she consults with organizations dedicated to strengthening families and improving the quality of care and education for young children. She has served on various related boards.
Ms. Miller holds an M.B.A. from Adelphi University and an M.A. in the Psychology of Parenthood from NYU. A passionate supporter of Adelphi, Ms. Miller has generously contributed to the Alice Brown Early Learning Center, and to various other University projects and programs.
For more information and the full day's program, please contact Adelphi's Commencement Office at 516.877.4695 or visit adelphi.edu/commencement.
Adelphi University is a nationally ranked, doctoral research university offering exceptional liberal arts and sciences programs and professional training with particular strength in its Core Four—AU Arts and Humanities, AU STEM and Social Sciences, AU Professions, and AU Health and Wellness.
Founded in Brooklyn in 1896, Adelphi was one of the first coeducational institutions of higher education in New York State and is Long Island's oldest private coeducational university. Today Adelphi serves nearly 7,500 students from 38 states and 46 countries at its beautiful main campus in Garden City, New York—just 23 miles from New York City's cultural and internship opportunities—and at dynamic learning hubs around the state (New York City, the Hudson Valley and across Long Island) and online.
More than 100,000 Adelphi graduates have gained the skills, knowledge and exposure to thrive as professionals and active citizens in an interconnected and fast-paced global society, making their mark on the University and the world beyond.
Our history, location and commitment to student success and academic excellence define the Adelphi Advantage.
Kali Chan
Director of Media Relations
p – 516.877.4040
f – 516.877.3266
e – email@example.com

subset: commoncrawl


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City's tax rate not highest
After reading the Cheers and Jeers on May 11, I have some good news for Gloversville taxpayers: You're not the taxpayers with the highest property tax rate in New York state.
About 21 tax parcels in the former Bleecker School District No. 5 in the town of Caroga – which were combined with Bleecker District No. 4 back in 1923 and then combined with the Gloversville school district in 1964 – pay a town tax rate of $27.05 per $1,000 of assessed property value and a staggering Gloversville school tax rate of $48.34 per $1,000, for a total of $75.39 per $1,000.
Where a Gloversville resident pays $3,699 on a $70,000 assessment, residents on those roughly 21 parcels pay $5,276.88 in this district.
Ironically, they haven't sent a student to these schools that we can document since 1923. They have gone to the Wheelerville Union?Free School District at no cost to Gloversville.
If they chose to go to Gloversville, their school bus would have to pass through the Wheelerville district to pick them up and return them.
Caroga Lake


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6 posts tagged with animation by Greg Nog.
Displaying 1 through 6 of 6.
Animating a Jump: Part 269
Animating a Jump Tutorial Video, Part #269. (SLYT, 2m10s, shades of Duck Amuck)
There's A Man In The Woods
There's A Man In The Woods. (vimeo, 3 min 36 sec) 4th Year Animation Project by Jacob Streilein.
Animation Pals
Four under-a-minute Animation Pals shorts, so far: Episode One: Introduction. Episode Two: Nude. Episode Three: An Impressive Butterfly. Episode Four: Training. You can follow them at the Animation Pals tumblr. Voiced and animated by Adventure Time's Pendleton Ward and Ian Quartey-Jones.
Jingle Cats, Crawling in my Skin
Jingle cats SCREEN TEST - Crawling in my SKin. Ayuh, seems like Christmas comes earlier every year. [more inside]
Bird Box Studio
Bird Box Studio makes short, simple, wordless, slapstick-heavy, fantastic cartoons. Bird Box UFO. Sketchy Ice Creams. Sketchy Blues. Sketchy Duel. Sketchy Guard. More available on the BBC's "headroom" website. brought to my attention by yoga in this thread
Avatar Two: Eclectic Bendaloo
The creators of Avatar: The Last Airbender have confirmed that they will be making a new miniseries, set 70 years in the future. Despite the poor critical reception of the live-action Shyamalan adaptation, the animated world will continue. [more inside]
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Around 25 million Americans are afflicted by the disease at present. Jargon is basically defined because language that covers a specific career field or interest. The pharmaceutical industry and the people which can be concerned consider this to be survey conducted by Drs.
My Care Pharmacy offers Trust, Private, Convenient, Affordable replacement for conventional pharmacies. If you have a refillable prescription at one of those stores, you will probably find yourself driving across town to their round-the-clock location after hours. All you might be required to do is fill out an online questionnaire which is reviewed by an experienced doctor.
' Truck drivers, food services, alcohol and drink creation and distribution are safe. Assisting pharmacy technicians are pharmacy aides, sometimes called clerks or cashiers. We cover actual clinical material and learn how to make clinical decisions within an ideal setting.
If you happen to be exploring a pharmacy technician career, this question must be in the top of your head. This is smart because you may not have to enter your contact details every time you shop with them. Side effects include: Increased urination (most popular with loop diuretics, for some people this subsides within a few weeks), too much potassium within the blood (with potassium-sparing diuretics), weak hands potassium in the blood (with thiazide diuretics), breast enhancement in men, increased blood sugar levels, increased cholesterol, male impotence (ED, impotence), low blood sodium, rash, gout (joint inflammation), and menstrual irregularities. For probably the most part, pharmacists and pharmacy staff really do care about the patients.


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Public Comment Opportunities
Public Comment is an opportunity for all stakeholders to provide input and feedback on all facets of ICANN's work. Find and participate in Open community discussions, review past work and browse upcoming topics.
To learn more about Operational Consultations, please visit this page.
Open for Public Comment
Identifier Technology Health Indicators: Definition
Updated Supplementary Procedures for Independent Review Process (IRP)
Proposal for Thai Script Root Zone Label Generation Rules (LGR)
Proposed Renewal of .MOBI Sponsored Registry Agreement
Proposed Charter Amendments of the GNSO Business Constituency
Recently Closed for Public Comment
Continuous Data-Driven Analysis of Root Server System Stability Draft Report
Proposed ICANN Community Anti-Harassment Policy
Proposed Implementation of GNSO Thick RDDS (Whois) Transition Policy for .COM, .NET and .JOBS
Revised Proposed Implementation of GNSO Thick Whois Consensus Policy Requiring Consistent Labeling and Display of RDDS (Whois) Output for All gTLDs
Proposal for Lao Script Root Zone Label Generation Rules (LGR)
Draft PTI FY18 Operating Plan and Budget
Phase II Assessment of the Competitive Effects Associated with the New gTLD Program
Proposed Amendment to .XXX Registry Agreement to Transition to New Fee Structure and to Adopt Additional Safeguards
Middle East and Adjoining Countries 2016-2019 Strategy
Latin American and Caribbean DNS Marketplace Study
Upcoming Public Comments
A vital element in ICANN's processes is the opportunity for public comment on each substantial piece of work before it is considered for approval. In order to keep the community informed about future public comments, this page provides summary data for topics that are being considered with links to relevant documents that can provide fuller descriptions and background information where applicable. The topics and dates presented are offered as informed predictions of when certain forums are expected to be initiated, but should not be relied on as specific date announcements.
Upcoming public comments may be found on this page.
How Public Comment Works
Public Comment is a vital element in ICANN's decision-making process whereby the community is given an opportunity to comment upon proposals initiated by a working group or staff department. Each proceeding is open for at least 40 days. This page contains information about topics that are currently OPEN or have RECENTLY CLOSED.
Follow and Submit
We encourage you to sign-up and log-in to icann.org to receive public comment updates about when proceedings open and close for comment and when staff summary reports are posted. Submitting comments requires adherence to ICANN's Expected Standards of Behavior.
Staff Summary Report Inquiry
If you believe an error has been made in a public comment staff summary report, please send an email to firstname.lastname@example.com in which you identify the proceeding, explain the nature of the error, and recommend an appropriate remedy.


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HHS Secretary Kathleen Sebelius on Thursday announced $51 million in grants to assist states in creating exchanges designed to allow consumers to compare and buy health insurance plans over the Internet. "We are working hand-in-hand with states as we carefully implement the exchanges to make sure they best meet people's health insurance needs," Sebelius said.
Full Story:Government Health IT magazine


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Topic: WWE Raw
USA Network Is Trying to Reach Millennials With More Dramas and More WWE
Expect sci-fi series, SmackDown and fewer scripted comedies
By Michelle Castillo on Apr. 7, 2015 - 2:47 PM EDT
USA Network understands that audience demographics are changing. To further appeal to the mainstream, the NBCUniversal property is working on a new strategy to reach millennials. USA announced Tuesday at its…
Stephen King's Under the Dome Drama Is a Hit for CBS
Four weeks in, ambitious summer series is still going strong
By Anthony Crupi on Jul. 16, 2013 - 8:21 PM EDT
Four episodes in and it's clear that CBS has a rare summer drama hit on its hands with Under the Dome, a claustrophobic yarn about a small town that is…
Tweet My TV Show
Keys to Social TV: Charlie Sheen, SpongeBob and 'Love and Hip Hop Atlanta'
By Lucia Moses on Sep. 11, 2012 - 6:15 AM EDT
Used to be, television viewing was a passive experience. Today, the vast majority of smartphone and tablet owners are tapping away on their devices as they watch TV—creating more opportunities…


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Castle Hotel
No prices found through our partners. Please contact the business directly or check some of our recommended alternatives.
How has this hotel rated in the past?
- Free High-Speed Internet
- Room service
- Restaurant
- Bar/lounge
- Free parking
Photos of Castle Hotel
Travelers also recommend:
- Restaurant
- Bar/lounge
- Free High-Speed Internet
- Free parking
- Room service
TripAdvisor Reviews Castle Hotel Neath
Travel Blogs from Neath
How did I manage to make it to adulthood?
... accommodation voucher and driving reference in separate poly pockets, arranged chronologically in one slim, professional-looking file. All for nothing. Because I left it there. On the chair. Eighty miles away at this point. Nothing like a sudden drama to make you reconsider whether it's safe for you to travel halfway across the planet without a ...
Finally, a castle
... They apparently even handed out seeding calenders.
If you want to know more about the keep itself, you'll have to ask Alexis, as she stole my audio tour player by means of asking nicely, and listened to the funny bloke all the rest of the way. Her english grades better be amazing.
We left the castle and ambled about the old town until we found the old Victorian market place, where we bought enough food to give us two homecooked meals. ...
Oewieoe, tumtudum!
... Weeping angels? Nah, not important, where are my Daleks?
The museum itself was quite interesting, although it is painfully obvious how much was chucked in the garbage back when BBC thought it was but a passing fad. A lot of the old collection, including a whole tardis console, is on loan from private collections. Unfortunately, the atrociously pink outfit from Sarah Jane Smith survived. More fortunate, we got to walk around in the ...
A Day in the Gnoll Country Park
Saturday morning started off sunny and bright! I was in the kitchen on my laptop enjoying the peace and quiet with a cup of tea and my MacBook Pro. I was startled by a noise at the kitchen door. I looked over and there was a bird flying up at the kitchen door glass, not really sure what it was trying to do but it was flapping its wings and jumped up repeated at the glass for about 5 minutes before it stopped!
Shortly ...
A Day in Margam Park
We had a bit of a slower start this morning, mainly due to lack of birthdays and presents to open lol :).
It started out a mixed day weather wise so we decided not to risk the beach and go to Margam Country Park and play cricket and football. Margam Park, just a few miles from Bedw Arian has a fairytale castellated mansion, 1,000 actress of land telling an 800 year old story through monastic ruins, to a restored exotic orangery (the longest ...


text: Offering a sun terrace and views of the river, Liberté is set in Amsterdam, 2,953 feet from Dutch National Opera & Ballet. Guests can enjoy the on-site bar. Some units feature a seating area where you can relax. Every room is equipped with a private bathroom. For your comfort, you will find free toiletries and a hairdryer. Liberté features free WiFi . There is a shared lounge at the property. A range of activities are offered in the area, such as cycling and fishing. The hostel also offers bike hire. Beurs van Berlage is 0.7 miles from Liberté, while Royal Palace Amsterdam is 0.7 miles away. The nearest airport is Schiphol Airport, 7.5 miles from the property.


text:
San Francisco, Miami and Vancouver help power growth as markets in Europe weaken
As grand English estates like Albury Park, Wyfold Court and Apley Park are subdivided into apartments, buyers find more affordable, low-maintenance retreats.
Cluttered, salon-style arrays of artwork have lost their mojo. What looks new: Framing similarly sized pieces identically and hanging them in a tight grid formation
Counties where 2015 home sellers made a 49% or better return on investment
Listing date: 07/14/2015


text:
Light blue and white tile.
Who put your lunch together when you were little?
Light blue and white tile.
Who put your lunch together when you were little?
Yup, with donuts!!
My Mom
What did you want to be "when you grew up?"
a school teacher
What is the distance from your home to the grocery?
"Show a dog an ounce of love and he'll be your friend for life." ~ Stuart and Linda Macfarlane
1 mile
What makes your city fun?
Yup, with donuts!!
The lake
What is your favorite sandwich?
Turkey and cheese
Who mends the clothes in the family?
Yup, with donuts!!
I do.
Who is the worry wart in your family?
My brother.
What topping(s) do you like on pizza?
~Supernatural Addict~
Ham, Pepperoni, Pork & Beef toppings, Italian sausage, Red Onions, Mushrooms, Green Peppers!!!
What is your Favorite Pizza Restaurant?
Pizza Chief
What color is your hair naturally?
Yup, with donuts!!


text:
[embedded content]
How about one final video highlight from this past weekend's UFC Fight Night 30, which includes Luke Barnatt's premature celebration but eventual submission win over Andre Craig?
The middleweight bout, which streamed online ahead of Saturday's FOX Sports 2 main card from Phones4u Arena in Manchester, England, saw Barnatt (7-0 MMA, 2-0 UFC) quickly recover from some early power shots from Craig (9-2 MMA, 3-2 UFC). However, after scoring knockdowns, the Englishman celebrated a bit too early.
However, it was no harm, no foul for the fighter, who eventually cinched up the submission win in the second round. Check out the highlights above.
Also check out the other UFC Fight Night 30 highlights:
For complete coverage of UFC Fight Night 30, stay tuned to the UFC Events section of the site.
Former UFC heavyweight champion Cain Velasquez has been forced out of yet another fight. This time it's his UFC 207 rematch with Fabricio Werdum that's been scrapped. Just one week before the Dec. 30 read news >>
In 2015, then-interim champion Fabricio Werdum unified the heavyweight titles against Cain Velasquez at UFC 188 with a submission finish. read news >>
Ronda Rousey was once one of MMA's most dominant athletes. Now, ahead of UFC 207, her doubters seem to outweigh her supporters. Can she beat Amanda Nunes?Filed under: Featured, Featured Videos, News, read news >>
UFC 207 has lost its heavyweight showcase, but the show continues on with 10 fights. Cain Velasquez didn't get the Christmas present he wanted. The Nevada Athletic Commission (NAC) pulled Velasquez f read news >>
UFC bantamweight champ Dominick Cruz takes his racing almost as seriously as his fighting. Cruz fights Cody Garbrandt in the co-main event at UFC 207. read news >>
Cain Velasquez is officially out of his scheduled UFC 207 rematch against Fabrcio Werdum after failing to be approved by the Nevada State Athletic Commission. read news >>
If you're heading to UFC 207 this week, don't expect much in the way of pre-event activities.Filed under: News, UFC read news >>
Two former heavyweight champions were set to rematch next week at UFC 207, though no belts were on the line. However, prior to that second fight, Cain Velasquez was ruled ineligible to face Fabricio read news >>
Before he fights UFC bantamweight champion Dominick Cruz at UFC 207 on December 30, learn about Cody Garbrandt and his special friendship with young Maddux. read news >>
UFC 207 is drawing near, and UFC fans of all stripes are getting excited for the card – and the two title fights sitting atop it.Filed under: Featured Videos, News, UFC, Videos read news >>


text:
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Item #: WRT7116
WILSON Pro Open BLX Tennis Racquet
List Price: $190.00 Sale Price:
The manufacturer no longer makes this item. It is no longer available for purchase. For assistance finding a similar product click the "Get Help Now" button below or call customer service at 800-833-6615
Click here to read the Tennis Express Review
Get $10 off select Wilson shoes when you purchase this racquet! Plus, get free shipping and free stringing! Proceed to checkout for details.
The racquet that is largely responsible for the creation of the Power and Spin line, the Wilson Pro Open BLX gets a new appearance for the 2012 season. Hugely versatile, this frame features all the classic features of a tweener frame, from the taper beam to the 100 square inch head size. What makes the Pro Open BLX different is its focus on feel rather than just power. Complete with basalt fibers within the graphite matrix, harmful and unwanted vibrations are filtered out, resulting in a crisp feel while remaining comfortable. At 10.5 ounces unstrung, there is nothing that this frame cannot do in the right hands. Our testers found plenty of spin off ground strokes and the power level allowed some mistakes when pulled out wide, showing that this frame has no weaknesses.
Note: Wilson does not provide a cover with this racquet. Please check out our complete selection of Wilson bags.
For more information on choosing a racquet, please see the Tennis Express Buyer's Guide.
|Head Size:
|100 sq. in MP
|27 inches
|Strung — 11.1 oz Unstrung — 10.5 oz
|53-63 pounds
|7 Pts Head Light
|Beam Width:
|26mm Dual Taper
|Basalt/Karophite Black
|Grip Type:
|Pro Hybrid
|Power Level:
|String Pattern:
16 Mains / 19 Crosses
Mains Skip: 8T, 8H
One Piece
No Shared Hole
|Swing Speed:
|Swing Weight:
Pro Open BLX Tennis Racquet
User: doug tran, California
Personally, I think it is a mediocre racquet for this price range. It is head light but not a stable and accurate racquet for long, fast swings. However, the feel is great and the vibration is virtually none upon ball impact. If you are used to long, fast swings with 11 oz plus racquets this one is not for you.
Wilson Pro Open BLX Review
User: Winnie Wong, ca
-The racquet has a good balance of spin and control. The lite weight material makes it easier for me to whip the ball. I am very satisfied with the results it has provided with me so far and I look forward to seeing a newer version!
Love it..!
User: Giselle Gonzalez, Puerto Rico
It feels strong and light at the same time... Like it so much!
Try it!
User: Tracy Wong, Tx
After being away from the game for over 10 years, I tested a lot of demo rackets before settling on this one. I love the control and stability of the racket. Im very happy with the overall playability of the racket.
Racket Review
User: Felipe Couto da Silva, Brazil
Great Racket has improved my tenis a lot! I have the same old model and this new one just improved the material and the balance from the last one. I am using the Wilson Sensation String and the racket is better than never! Thanks a lot.
Its the complete package
User: Daryl Rosenblatt, NY
I cant simply say its a great racket, because I wouldnt have gotten it its actually my second BLX Pro Open, because you MUST try out many rackets to find one that suits your game. Mine is an all court type of game, and after 40 years of playing with either an Ashe II or a Head mid size, or a Yonex graphite --all of which needed the old style of play, I decided it was time for a 56 year old dog to learn new tricks. The new game is power and topspin, and for that, you need to counter with a new racket. This one is light, well balanced, and gives a great compromise for all aspects of the game. However, a review of a racket alone for Tennis Express is incomplete. They strung it just the way I wanted a hybrid, Babolat gut on the mains, Luxilon rough on the crosses, and at the right tension. So when you get the racket you want, done the way you want, and get it just when they say you will, you have to say you are a happy customer.
Great, great racket
User: Addison Tackaberry, Texas
The power and spin provided by this racket is a thing of beauty. Wouldnt play with anything else. Wilson is at the top of the class here.
in awe
User: james fultz, fl
very great in all areas,needs nothing.4.5 player,used all the high end rackets,if your looking for comfort this is it,if for power sensations at 57 perfect,f for feel,same sensations at 57 play for 4hrs ,bam the perfect set,on serves,no worries,returns too easy,baseline use yor body hv no worries,very great racket for all players .you will not be disappointed.
- Customer Video Reviews
See any errors on this page? Let us know


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Flight Level 110 tips
- App name: Flight
- Developer: Armor Games
- Genre: Adventure
- Release: Jul 19, 2012
If you are stuck on Flight level 110 you came to the right place. Below you will find a video walkthrough and some written tips that will guide you through that level. Have fun and enjoy this great game.
Level 110 Walkthrough
This page contains Flight video walkthroughs for iOS (iPhone/iPad) called "my office from" and has been uploaded on lucasmj2004 official channel at Sep 2, 2013.
Still need help with this level? Here you can ask questions and discuss with other Flight users.
Hit like if this helped you!
Stuck on some levels in Flight? This walkthrough can help you finish the game.


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- 08-10-2014, 11:00 AM Thread Author #1
Unfortunately, the process com.android.phone has stopped
Well I'm not too good with phones and should not of tried but I got a good pair of earphones so while watching you tube videos I routed my phone and put Cyanogen Mod on there.
Then I started looking for ways to improve the sound and tried the Boeffla kernel but it had some problems so then I found this one called Siyah Kernel and tried this but now, after I rebooted the phone, it has a message saying "Unfortunately, the process com.android.phone has stopped"
If I press OK the message returns instantly and there is no way to unlock the phone to get access.
I tried plugging it into a PC and using MobileGo but it can no longer connect and it dose not show anywhere up on the PC as attached.
So I'm stuck, it's a Galaxy S3 Gt-i9300 running Cyanogen Mod 10.2 with the Siyah Kernal, Siyah-s3-v1.9.1-CWM.zip. Can anyone help me please?
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Charlie Hunnam Gossip
Charlie Hunnam gossip, latest news, photos, and video.
Charlie's "unique love story"
Jacopo Raule/ Karwai Tang/ Getty Images
Drake Doremus's movies are always about love. Like Crazy was about love. And Equals was about love. And the people who are in love are young and hot. According to The Hollywood Reporter, his next movie is, once again, about love. And the stars of his next movie are really, really hot. Full Story
Charlie's push-ups
No one should have to work after this post. It's nearing the end of August. I have a few days of hiatus left. And I feel like after seeing these pictures and watching these videos, we all deserve a break. WHO CAN WORK WHEN CHARLIE HUNNAM IS DOING PUSH-UPS? And, as a bonus, he stepped out yesterday to the dentist, giving us some new pictures to go with this article. Full Story
Lock, Stock, and Arthur Snatch Sherlock
Vivien Killilea/ Stefanie Keenan/ Kevin Winter/ Getty Images
Guy Ritchie's Knights Of The Round Table now titled King Arthur: Legend Of The Sword was supposed to be released this summer. Late last year it was announced that the movie would be pushed to first quarter of 2017. Full Story
Charlie Hunnam on red carpet
Wenn, FameFlynet, Barry King/ JB Lacroix/ VALERIE MACON/ Getty Images
Theme of the day: distraction. Big G came through, Idris came through, Swoki keeps coming through, and look… it's Charlie Hunnam. Who is not a red carpet regular. Who doesn't just show up wherever he's invited. Full Story
Charlie & Morgana go shopping
LA Photo Lab/ Splash News
Charlie Hunnam and his partner Morgana were photographed shopping this weekend. Seemed happy. Smiled for the paps. I was surprised to see new shots of him so soon after the last post on Friday Full Story
Charlie Hunnam on a Friday
Cousart/ JFXimages/ WENN
It's a travel day today and I'm still finishing up a live show which is why I'm serving up some quick hits. Hoping to have some time for longer posts at the airport and if there's a wifi connection on the plane but if not I'll load you up on Monday. Also, you don't typically need many words when it comes to Charlie Hunnam Full Story
John Boyega takes over for Charlie Hunnam
Lia Toby /WENN
Do you remember Pacific Rim? It's Guillermo Del Toro's kaiju vs. robots movie that stars Charlie Hunnam and Idris Elba as the guy who cancelled the apocalypse Full Story
Memorial Day Charlie
Charlie Hunnam was seen on Memorial Day weekend with his partner Morgana McNelis and his family. So, continuing my intention today to begin the blog with relationship calm (before we get back into the mess of Amber and Johnny), there's your update on his romantic status. Full Story
Charlie in New York
This weekend was already amazing, what with Beyoncé's Lemonade and Game Of Thrones and now new pictures of Charlie Hunnam. He was in New York the other day with his partner Morgana McNelis. She is tall. I always forget that she's so tall. Like 5 ft 9 at least, I think? Anyway, it's been 6 weeks since I last posted about Charlie (that's why it's such a treat to be kicking off the week with him) and the last time we talked about him he was defending Morgana from the JaxHards who were dragging her for, I dunno, being his girlfriend. Full Story
Charlie Hunnam's messages for the JaxHards
Here's the situation as I understand it, because it's hard to understand crazy f-cking fans. There's someone who runs a Facebook fan club for Charlie Hunnam. Her name is Tina. And people were being dicks on Facebook about Charlie's girlfriend, Morgana. I guess Charlie found out about it and asked Tina to post a message that he wrote on the fan page telling them to not be so TwiHardy about his partner. Full Story
Charlie Hunnam and Jake's high notes
Here are these new-ish shots of Charlie Hunnam. And he looks hot. So I wanted to post them yesterday. But then, beyond that, I didn't have anything to say. I still don't. Then, this afternoon, a few readers have sent over video of Jake Gyllenhaal last night at Lincoln Centre for Leonard Bernstein Takes Over The New York Philharmonic and, well, even though the only connection here is that they're both really attractive, I'm putting them in the same article. Full Story


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"There are a lot of organizations doing political organizing, but I think we're working on something different here in terms of talking about it as a community. It really struck home for me when we had the Shabbat dinner for gay and lesbian marriage."
Social Justice
A core expression of our Jewish identity at the Boston Workmen's Circle Center for Jewish Culture and Social Justice is the pursuit of a besere velt — a better world. We weave that commitment into every layer of the community, including our holiday rituals, arts and culture programming, and our children's Sunday School.
Inspired by the 110-year history of the Workmen's Circle, we are proud to stand up as a progressive American Jewish voice on social and economic justice issues as well as on Israel. And we are proud to be a community that makes room for the respectful airing of differing views on issues that can be controversial.
We provide progressive activists with a place to energize. We act together, mobilizing around social justice issues that speak to our identity as Jews and as activists.
Our social justice committees lead the way. New members are always welcome!
Our work for a just peace between Israel and Palestine is guided by a commitment to ending the occupation, establishing two viable states, ending violence on all sides and making room for diverse views.
Organizing community allies to support local labor and immigrant struggles is a priority of the Acting for Racial and Economic Justice Committee, along with participation in the Greater Boston Interfaith Organization (GBIO).
Through political action, relationship building and community education, the BWC Jewish Muslim Relations Committee works to foster positive ties between Jews and Muslims in Greater Boston and joins with the Muslim community in opposing Islamophobia in all its manifestations.


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Hackerspaces in Boston
Artisan's Asylum
If you need a lot of space head to this nonprofit community craft studio for working, storage, or even manufacturing. Feel free to spread out in this 40,000-square-foot warehouse in Somerville. Gui Cavalcanti is president of Artisan's Asylum. Next
Bocoup Loft
Bocoup Loft is a Web consultancy/hacker space near South Station that also hosts events and houses coworking desks. Next
Cambridge Hackspace
Cambridge Hackspace welcomes anyone and everyone to collaborate. They describe their hackspace on their website as a "community-operated physical place where people can gather and work on their projects, from coding to quilting and anything in between." Next
hack/reduce is one of the more well-known hackspaces in the area. Their slogan "Code big or go home" says it all. They specialize in big data projects at their Kendall Square locale. hack/reduce was established in partnership with the Commonwealth of Massachusetts, local innovation firms, and the nearby universities. Next
Ideas to Things
One of the newer hackspaces, Ideas to Things, resides in Sullivan Square. Hit them up if you want to be a part of a brand new venture and help it progress. Next
MIT's hackerspace is — as expected — much more active in the school year. When you get your fill of the computers, there are also band saws, welders, hands-on, and prototyping tools to play with at MITERS. Check out what they've done before. Next
P.irateship is a hackerspace / coworking space in Union Square where members share the rent. Boston's Public Laboratory chapter is housed there. Back to the beginning


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Ressource publié par Causecast
Créé le : 28 févr. 2013
According to the National Center for Charitable Statistics (NCCS), over 1.5 million non-profits are registered in the U.S. While many of them receive assistance through corporate philanthropy and employee volunteerism, in general all of them compete for a limited giving pool. So how can nonprofits stand out among all the noise, especially if you're a small, grassroots organization championing an underserved and mainly unnoticed population like foster children?
How can your organization leverage a companies community service?


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December 28, 2009
State Of The Industry: Leaders Sound Off
Read More
So many questions, so many different answers. Determining whether the state of our industry is good, bad or something else is a mighty challenge when you take into account the fact that growers, retailers and others have vastly different opinions on the issues pressing us most. Business may be booming for some yet hard to come by for others, and a challenge to one grower may be the least of another's worries. To give you an idea where people in the industry stand, we approached growers and others with five questions about the state of greenhouse floriculture in 2010. Most of those we approached expressed concerns about the state of things. But here's what they said − in their own words. How would you describe the state of the greenhouse floriculture industry today? Fran HopkinsPresident, Under A Foot Plant CompanyIn complete disarray and total pandemonium. I must say this […]
December 22, 2009
Five Questions With … Denise Godfrey
Read More
Denise Godfrey of Olive Hill Greenhouses in Fallbrook, Calif., shares her take on the state of the industry this week. How would you describe the state of the greenhouse floriculture industry today? Like the rest of the economic sectors, we are suffering from decreased demand and we hope to maintain during this uncertainty by looking at old and new ideas and technology; by relying more on relationships and working together with fellow growers, suppliers and customers to better define and react to what is happening; to take advantage of opportunities; and to maintain a positive outlook in order to overcome adversity and persevere. Has our industry entered a new era or paradigm shift? Please explain why or why not. We no longer grow in a vacuum, growing and selling plants and the customer deciding their purchase on beauty and a fair price. The public is having more and more influence […]
December 15, 2009
Four Questions With … John Bonner
Read More
As part of our State Of The Industry report, we asked industry leaders to answer questions about the state of all things greenhouse floriculture. John Bonner, general manager of Eagle Creek Wholesale in Mantua, Ohio, shares his take on the state of the industry this week. How would you describe the state of the greenhouse floriculture industry today? The industry is in flux and going through some serious changes. Has our industry entered a new era or paradigm shift? Please explain why or why not. Yes, the new paradigm is one of accountability for making sure not only our customer is successful, but even more importantly, the consumer. This mantra is rippling back through the supply channels. Creating value also seems to be the law of the land today. What are the greatest challenges growers are facing today? Our greatest challenges are creating programs and products that are relevant to […]
December 4, 2009
Three Questions With … Art Van Wingerden
Read More
Art Van Wingerden, president of greenhouse operations at Metrolina Greenhouses in Huntersville, N.C., shares his take on the state of the industry this week. How would you describe the state of the greenhouse floriculture industry today? We think the state of the industry is good right now. Not good for everyone, but the overall state is, we think, good. Has our industry entered a new era or paradigm shift? Please explain why or why not. We have hit a shift. If you told growers a few years back they would be contract growing, they would have told you no way. The number of people who contract grow for others is increasing every year. We are currently at 25 percent of our sales is grown by others. Has there been a changing of the guard in industry leadership? Please explain your answer. Not sure about this one. Who says who is […]
December 1, 2009
Five Questions With … Fran Hopkins
Read More
Fran Hopkins, president of Under a Foot Plant Co., shares her take on the state of the industry this week. How would you describe the state of the greenhouse floriculture industry today? In complete disarray and total pandemonium. I must say this is the most disturbing place I have ever been in as a grower, as an owner and as a marketer. Instead of a unified front, forging forward in this horrible economy, we are regressing into civil war–box store versus independent, generic versus brand, paper versus plastic. You name it, our industry has pushed itself into every corner it can with a fight or flight mentality. I used to love this industry, but going to meetings now is a dreadful undertaking. It's vigilante time for many I think. Instead of pulling together and finding a common cause to whip this bad economy, my friends and colleagues are yelling at […]
November 30, 2009
Industry Infection
Read More
Whether your political views are conservative, liberal or somewhere in between, we can likely agree Americans are as politically divided today as they've been at any point in our lifetimes. To me, the political division is OK. I should be able to think one way while you think another. We all have different backgrounds and needs anyway, and what's viewed as an economic, foreign policy or health care solution to one person may be a new set of problems to another. The real problem today is how we're addressing our differences. Civil discourse and spirited debate are gone, and Americans are resorting to name calling, screaming at the top of their lungs and playing the blame game to get their points across. Look no further than a couple of cable news networks that often make news based on how the other network covers a big story. Mud slinging between networks […]
November 19, 2009
Lowe's Experiences Large Drop In Earnings
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As of October 30, Lowe's reported earnings of $344 million. This total is a 30 percent drop from the $488 million reported in earnings this time last year. Despite recent declines, analysts say good things are ahead for the home-improvement retailer. "We are seeing signs of improved performance in some of the hardest-hit housing markets, including California, Florida and areas of the desert Southwest," says Lowe's CEO Robert Niblock. Analyst Michael Lasser of Barclays Capital, says while Lowe's sales trends have been negative, the retailer "is seeing a recovery" as gains have been made over second-quarter results. Read on for more on Lowe's third-quarter fiscal profits and the company's overall performance.
November 18, 2009
Standards Committee Calling For Applicants Again
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Leonardo Academy is looking to fill five seats recently vacated on the National Sustainable Agriculture Standards Committee. The organization encourages growers interested in engaging in dialogue on sustainable agriculture to apply for the seats. The 58-member standards committee is in the process of developing a national standard for sustainable agriculture under the rules of the American National Standards Institute (ANSI). The committee consists of a skilled, diverse membership representing a broad range of perspectives from across all areas of agriculture, including commodity producers, specialty crop producers, agricultural product processors, food distributors, food retailers, environmental organizations, labor organizations and industry trade associations, as well as government representatives, academics, regulators and certifiers. In addition, the committee created six subcommittees it has been working with since July to develop the outline of the standard along with draft economic, environmental and social criteria for the committee to review at its next in-person meeting. The […]
November 17, 2009
Anna Ball's Top Trends In Horticulture
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Ball Horticultural Co.'s CEO Anna Ball recently shared her insights with woody ornamental growers at the International Plant Propagators Society's Eastern Region meeting in Cleveland. Here are her top trends: Sustainability Sustainability continues to top her list, and as a company, Ball has been the leader in creating a sustainable supply chain for growers. Sustainability is the fifth wave of innovation to transform our industry, the way plastics and soilless media revolutionized our industry in the 1960s, she says. Sustainability isn't a project or program but a new way of doing business. "It's not a goal on the strategic plan but part of everything you do," Ball explains. "It's a vehicle to drive innovation in all different areas. To create a sense of urgency, we need to act as though oil were $300 a barrel, water availability were cut in half and weather variations tripled." She advises growers to embrace […]
November 10, 2009
Garden Media Group's Seven Trends For 2010
Read More
Public relations firm Garden Media Group just released its annual trends report to show what they anticipate will be hot in 2010. "Just look around you," says Susan McCoy, trend spotter and outdoor living expert. "Our relationship with money has changed. Hard work, common sense and a return to small-town values are causing a shift in priorities from boardrooms to backyards. "The rewards of growing your own – from basil to berries to flowers – are boundless." Here is a glimpse of what McCoy and her team of trend spotters see for 2010. 1. Main Street is in. Wall Street is out. There's a shift of priorities between balancing practicality with comfort and fulfillment. "Core values of responsibility, meaningful relationships and connectivity to neighbors and communities are surging," says McCoy, president of Garden Media Group. That "can-do" spirit empowered by a new sense of self-sufficiency is fueling a renewed appreciation […]
November 3, 2009
New Niche For Struggling Nurseries
Read More
Oasis of the Sea, the world's largest cruise ship, has created some much needed and unexpected business for Florida's hard-hit landscaping market. More than 12,000 plants will be used in the ship's Central Park, which is an open-air green space that spans more than a football field at the center of the 5,400-passenger ship. Florida's Michaels Nursery and Southeast Growers are growing the bulk of the plants. "This is a real big thing for us, a real shot in the arm," says Bill Churchill, general manager of Michaels. Churchill declined to disclose estimated profits but said the cost of the plants alone is about $15,000. One garden will have plants native to Caribbean destinations, so guests will see shade-grown coffee plants, budding pineapple plants and learn about the origin of spices, such as cinnamon and nutmeg. The park's horticulturalist will give tours and offer passengers gardening tips, reports The Sun […]
October 29, 2009
Survey: Economy Impacts Holiday Spending
Read More
The National Retail Federation (NRF) recently released the results of a survey that focused on the spending habits of Americans this holiday season. Last year, consumers spent an average of $705 on holiday-related shopping. This year, that amount is expected to drop to $682.74. Here are additional results from the survey: –Forty-three percent of holiday shoppers surveyed said sales and price discounts will be the most important shopping factor.–Seventy percent will shop discounters, though 55.8 percent will also purchase from department stores.–Thirty-nine percent of shoppers will begin holiday shopping before Halloween, and 75 percent of the holiday budget will be spent on gifts.–Spending on family members is expected to drop 2 percent, while spending on co-workers and friends is expected to see double-digit drops. For more results, read the entire NRF survey article.


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Toyoko Inn Hankyu Jusoeki Nishiguchi
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Fish Market and Asakusa
... station, I am completely lost not sure which way to go, I literally have to circle the entire perimeter of the city area before I finally find my way back to tsutenkaku. By this time I am so hungry, I checked into the Okonominoyaki restaurant and ordered their most famous one. It's sure worth the wait and walk, absolutely delicious, and t hey grill Okonominoyaki right in from of my eye. After dinner, I took the local train back, so much easier, but as soon as I returned, ...
Osaka, Day 2
Today we were up once again bright and early at 5:00 AM. It turns out not much is open at this time except Starbucks, so lucky for me, this is generally where we will start our days! We headed down to the JR ticket office in Osaka station after grabbing coffee to exchange our order form, as well as reserve seats to Kyoto for tomorrow. Once it was late enough that the Aquarium would be open by the time we got there (it's about half an hour away from where ...
Osaka and lost luggage in Singapore
... we were up first thing to get on our next plane to Singapore via Kuala Lumpur. Nothing in this world could have prepared us for the chaos that was Kinsai airport in Osaka!
There were people everywhere! The queue for customs stretched right to the end of the terminal, with 3 people across, which left us severely worried that we wouldn't be able to clear in time for our flight even though we had arrived over 2 hours early.
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Last day in Japan
... of all ages were so friendly and accommodating; so many smiling faces.
Japan is definitely a step ahead of the US in regards to technology….I love the toilets. I love them so much I may just get one for home. Everyone will be invited over to try it!
The country is the size of California with 4 times as many people, but it never felt crowded. Kana told us that everyone is raised to live together in harmony and it's just ...
Sendai, Nagoya, Osaka, Kyoto & Ferry Adventure
... the Key Bridge coming out of Baltimore.
Our first day down south we spend at an F-1 Race Exhibition at the Suzuka Circuit. There weren't any actual races being held, but instead the had each of the different types of vehicles that race there do several laps around the track. While we didn't have that thrill of seeing the racers push full out, it was ...


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This a wonderful hand-carved and painted miniature "Mallard Hen" decoy with glass eyes, detailed feather painting and realistic coloration. Created by master Illinois carver, Charles Moore, from De Kalb, Illinois. Mr. Moore who carves in the Illinois River style has been carving for over 40 years; this decoy is from early in his carving career. He is also noted for his expert restorations of works of prior greats from his field.
The decoy measures 7 3/4" in length, 3 3/8" in width and 3 1/4" in height. Marked on the bottom "Chas. Moore '74". This is as close to mint as the day it was completed. If you collect and enjoy contemporary carving and know of the work of Charles Moore you will want this great Mallard Hen for your collection.
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I transfected myplasmid into chemically competent cells (E.coli) and let them grow overnight at 37°C, upside down. However, in the morning, there were no colonies, only a thiny plaque and, importantly, the agar was dried out (it was much thinner than yesterday and shrunk).
What can be cause for this?
Thanks a lot
Submit your paper to J Biol Methods today!
Agar has dried out during cultivation
Started by torte, Nov 22 2011 12:23 AMcloning agar no colonies
1 reply to this topic
Posted 22 November 2011 - 12:23 AM
Posted 22 November 2011 - 05:01 AM
Very dry air and incubator temperature cause evaporation from the surface of plates. You can make this less of a problem with a pan of water in the incubator, or by putting your plates in plastic bags (or sealing with parafilm).


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An old photo postcard...untouched by look of it...very natural feel to it. Has an 89 written in white at bottom right corner...could refer to 1889...looks old enough. Measures 5 1/2" x 3 1/2" and in pretty good order for age.Marked Postcard BARNET on back.
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At Molloy's MEGA ANTIQUES CENTRE, Takapuna, Auckland, New Zealand
Specialists in Pacific Islands Items, Victoriana, And a Fascinating Range of General Collectibles
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A new study reveals how the amygdala is involved in controlling predatory behavior in mice.
Exercise-Induced Muscle Factor Promotes Memory
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Running releases an enzyme that is associated with memory function in mice and humans.
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Running releases an enzyme that is associated with memory function in mice and humans.
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Researchers identify three new examples of infectious cancers affecting these invertebrates.
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Ancient DNA research suggests that there were two independent agricultural revolutions more than 10,000 years ago.
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A federal panel will review the first proposal for the use of the technology to edit human genes for medical purposes.
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Mouse pups born to mothers fed a high-fat diet lack a gut microbe that promotes social behavior, scientists show.
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Researchers aim to predict new infectious disease outbreaks that spread from animals to humans.
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A mouse study suggests that disruptions to nerves in the skin may contribute to autism spectrum disorder.
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A researcher documents electric eels jumping out of the water to shock potential threats, confirming a centuries-old anecdotal report of the behavior.
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Jazz Pharmaceuticals is set to purchase Celator to acquire an experimental treatment for acute myeloid leukemia.
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In Chapter 2 author J.D. Trout highlights the dividing line between truth and scientific "fact."


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Bloomington - Indiana looks to improve to 2-0 Saturday when it faces Murray State at 7 p.m. at Memorial Stadium. IU Coach Bill Lynch talks about the week two opponent, along with the return of Greg Middleton, the rotation at running back, and his impressions of Jerimy Finch...
AUDIO: Bill Lynch Weekly Press Conference
Peegs.com Top Stories
OG Anunoby out indefinitely with knee injuryIndiana sophomore forward OG Anunoby will be out indefinitely after suffering a knee injury on Wednesday night at Penn State, IU said tonight.
Peegs.com4:15 PM
Ellison thrilled to get Indiana offerOhio RB Morgan Ellison spoke to Peegs.com about how excited he is to land an offer from the Hoosiers.
Peegs.com2:54 PM
Indiana to host Big Ten baseball tournamentFor the first time ever Indiana will host the eight-team Big Ten baseball tournament.
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If Anunoby's out, how does IU manage?How does Indiana manage the expected absence of OG Anunoby? We take a look at where his minutes may go whether it is a short or extended recovery following his injury last night at…
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Coach Crean Verbatim: at Penn StatePeegs.com has the transcript of what IU head coach Tom Crean said after Indiana's 78-75 win at Penn State last night.
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Domino System Administration
€ 48,49
Besorgung - Lieferbarkeit unbestimmt
November 1999
BeschreibungThe comfortable, Old World of Lotus Notes has vastly changed. There's a totally new universal client that works for email, scheduling and even web browsing. 'Domino' now refers to both the plain vanilla Notes server as well as the totally new Internet Mail and Web server. Your administration duties have just been expanded to hosting web sites and supporting remote users through the Internet. Imagine for a moment that you're the administrator for Lotus Notes at Eli Lilly. You've been comfortably maintaining your user base since version 3.0. Most of your end users are running the Lotus Notes Mail client, and only accessing the server for email. You're comfortable with all of the routine maintenance and troubleshooting issues that are involved with managing a Notes Server. Now consider what happens when Lilly announces that it's going to upgrade to the newest version of Notes and Domino when it ships. As a Premium Lotus Business Partner, Lotus has offered a substantial price break to keep your company away from Microsoft's Exchange Server. How are you supposed to get this new system installed, configured, and rolled out to all 42,000 of your end users? You understand how Lotus Notes works - you've been administering it for years. What you need is a concise, practical explanation about the new features, and how to make some of the advanced stuff really work. You need answers and solutions from someone who's been in the trenches. Someone like you, who has worked with the product for years, and understands what it is you need to know. Domino System Administration from New Riders is the answer - the first book on Domino that attacks the technology at the professional level, with practical, hands-on assistance to get Domino 5 running in your organization.
InhaltsverzeichnisPLEASE PROVIDE
Untertitel: 'New Riders Professional Librar'. Sprache: Englisch.
Verlag: NEW RIDERS PUBL
Erscheinungsdatum: November 1999
Seitenanzahl: 880 Seiten
Format: kartoniert
Alle Preise inkl. MwSt., ggf. zzgl. Versandkosten


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MAT1A catalyzes a two-step reaction that involves the transfer of the adenosyl moiety of ATP to methionine to form S-adenosylmethionine and tripolyphosphate, which is subsequently cleaved to PPi and Pi. Zusätzlich bieten wir Ihnen Methionine Adenosyltransferase I, alpha Kits (18) und Methionine Adenosyltransferase I, alpha Proteine (14) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 53 products:
Human Polyclonal MAT1A Primary Antibody für EIA, IHC (p) - ABIN953327
Wu, Huang, Lu, Chien, Yeh, Tsai, Liao, Chen, Liao, Cheng, Lin: Thyroid hormone receptor-mediated regulation of the methionine adenosyltransferase 1 gene is associated with cell invasion in hepatoma cell lines. in Cellular and molecular life sciences : CMLS 2010
Zeige alle 4 Referenzen für ABIN953327
Human Monoclonal MAT1A Primary Antibody für EIA, IF - ABIN1108162
Chamberlin, Ubagai, Mudd, Levy, Chou: Dominant inheritance of isolated hypermethioninemia is associated with a mutation in the human methionine adenosyltransferase 1A gene. in American journal of human genetics 1997
Zeige alle 3 Referenzen für ABIN1108162
Human Polyclonal MAT1A Primary Antibody für IHC (p), WB - ABIN656632
Bing, Zhu, Yu, Li, Liu, Li, Wang, Qi, Guo, Yuan, He, Liu, Liu: Glucocorticoid-induced S-adenosylmethionine enhances the interferon signaling pathway by restoring STAT1 protein methylation in hepatitis B virus-infected cells. in The Journal of biological chemistry 2014
Chicken Polyclonal MAT1A Primary Antibody für WB - ABIN2776786
Oh, Yang, Hahn, Kim, Byun, Jeon, Kim, Song, Noh, Kim, Yoo, Kim, Kim: Transcriptome analysis of human gastric cancer. in Mammalian genome : official journal of the International Mammalian Genome Society 2005
MAT1A is required for normal VLDL assembly and plasma lipid homeostasis in mice. Impaired VLDL synthesis, mainly due to SAMe deficiency, contributes to NAFLD (zeige TSC2 Antikörper) development in MAT1A-KO mice.
Deletion of the TFIIH kinase subunit Mat1 in mouse fibroblasts leads to dramatically reduced RNA polymerase II Ser5 phosphorylation.
DUSP1 (zeige DUSP1 Antikörper) mRNA and protein levels are lower in Mat1a knockout livers and fall rapidly in cultured hepatocytes.
investigated the function of the Cdk7 (zeige CDK7 Antikörper).cyclin (zeige PCNA Antikörper) H.Mat1 complex in murine embryonic stem (ES) cells and preimplantation embryos to determine whether it regulates the unique cell cycle structure and transcriptional network of pluripotent cells
Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A
MAT1A knockout hepatocytes have more baseline DNA synthesis but no mitogenic response to hepatocyte growth factor (zeige HGF Antikörper). MAT1A-produced SAMe has a major role in ERK (zeige EPHB2 Antikörper) signaling & cyclin D1 (zeige CCND1 Antikörper) regulation during liver regeneration & mitogenic signal response.
Mat1a(-/-) mice have expansion of liver stem cells as they age. These cells have increased expression of several oncogenes and are tumorigenic in vivo.
C/EBPbeta (zeige CEBPB Antikörper) plays an important role in epigenetic regulation of the mature hepatic gene MAT1A
By 1 month of age, genomic instability increases in livers of Mat1a knockout mice, possibly due to reduced APEX1 (zeige APEX1 Antikörper) levels
CD133(+)CD45(-) oval cells isolated from premalignant 16-month-old Mat1a(-/-) mice demonstrated significant resistance to transforming growth factor-beta-induced apoptosis compared to CD133(-) cells.
High PED expression is associated with esophageal carcinoma.
The nuclear translocation of SApErk1/ 2 apart from PEA-15 (zeige PEA15 Antikörper) as an important mechanism to reverse senescence phenotype.
Latent HCMV infection of CD34 (zeige CD34 Antikörper) + cells protects cells from FAS (zeige FAS Antikörper)-mediated apoptosis through the cellular IL-10 (zeige IL10 Antikörper)/PEA-15 (zeige PEA15 Antikörper) pathway.
New therapeutic targets based around PEA-15 (zeige PEA15 Antikörper) and its associated interactions are now being uncovered and could provide novel avenues for treatment strategies in multiple diseases.
PED/PEA-15 overexpression is sufficient to block hydrogen peroxide-induced apoptosis in Ins-1E cells through a PLD-1 mediated mechanism
Omi/HtrA2 (zeige HTRA2 Antikörper) overexpression promotes hepatocellular carcinoma cell apoptosis and the ped/pea-15 expression level causes this difference of the Omi/HtrA2 (zeige HTRA2 Antikörper) pro-apoptotic marker in the various hepatocellular carcinoma cell lines
Results suggest that neurochemical adaptations of brain FADD (zeige FADD Antikörper), as well as its interaction with PEA-15 (zeige PEA15 Antikörper), could play a major role to counteract the known activation of the mitochondrial apoptotic pathway in major depression
Data show that phosphoprotein enriched in astrocytes of 15 kDa (PEA-15 (zeige PEA15 Antikörper)) influences dephosphorylation of epidermal growth factor receptor (EGFR (zeige EGFR Antikörper)) via extracellular signal-regulated kinases ERK1/2 (zeige MAPK1/3 Antikörper) sequestration in the cytoplasm.
5-Aza-CdR (zeige RUNX1T1 Antikörper) showed no effects on MAT2A (zeige MAT2A Antikörper) methylation.
Tumor suppressor PEA15 (zeige PEA15 Antikörper) is a regulator of genome integrity and is an integral component of the DNA damage response pathway.
This gene encodes a death effector domain-containing protein, which is a major phosphoprotein in astrocytes, and an endogenous substrate for protein kinase C. Studies using knockout mice suggest that this protein may protect astrocytes from TNF-induced apoptosis. This protein is also overexpressed in type 2 diabetes mellitus, where it may contribute to insulin resistance in glucose uptake.
CDK-activating kinase assembly factor MAT1
, CDK7/cyclin H assembly factor
, CDK7/cyclin-H assembly factor
, RING finger protein MAT1
, p35
, S-adenosylmethionine synthase isoform type-1
, S-adenosylmethionine synthetase isoform type-1
, adoMet synthase 1
, adoMet synthetase 1
, methionine adenosyltransferase 1
, methionine adenosyltransferase I/III
, S - adenosylmethionine synthetase
, 15 kDa phosphoprotein enriched in astrocytes
, Phosphoprotein enriched in astrocytes, 15kD
, astrocytic phosphoprotein PEA-15
, homolog of mouse MAT-1 oncogene
, phosphoprotein enriched in diabetes


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A solid cigar, I must say. Good flavor, nice draw, ash and smoke output. I'm a huge fan of Pepin or any My Father collection cigars. Love to revisit them as often as possible due to consistency of the cigars. I will say that my expectation from this cigar was huge and it's not as I expected, but a very good smoke indeed.
This stick is DAMN peppery & delicious as hell. HEAVEN! Must buy, & incredibly affordable price for A 20 COUNT GORDO BOX!
Is this the cigar that Pepin will be remembered by through the ages? No. But that doesn't mean this isn't a good stick. I bought a few a around when they were newish to the market and noted that while they had typical Pepin flavors I was craving, they seemed to be a little too "fresh". They got very bitter towards the end and I could only smoke around 2/3rds of the cigar before I had toss it. Fast forward to today and a year and some change has done beautiful things to this cigar. It has picked up a creaminess that seems to come about from the flavors melding together so well. Bitterness is completely gone from the last third and I'm kicking myself for not buying more. If you're picking up some sticks, do yourself a favor and buy just a little more so you can really enjoy these cigars down the road.
Ok! I said it was a good cigar, but after smoking it all the way to my fingertips, I decided that it's a great cigar. The longer it burned the better it taste. Delicious in flavor and I love the aroma. Definitely will keep these in my humidor. I'm not going to smoke my last one until I get the next box in my hands. Getting those today, woohoo!
Good cigar.
Just received another box of these great smokes. One of the best burns out there. Definitely one of my top two favorites especially at less than $5 apiece. Always have these and the Acid Kuba Grande in my humidor.
The question to ask. Can Don Pepin make a bad cigar? I've tried to smoke every cigar he had a hand in making & have never encountered any type of poor quality. As a cigar wizard he has his mojo working & smaller less known brands should learn as much as they can from his abilities. As one review pointed out, there are no soft spots on this. How in the hell can he accomplish this and other makers can't? Once again the 5 pack of Churchills I ordered will become a soon to come box. I can only hope that the low cost of these won't change any time soon. In agreement with another review, this is bold but nothing over powering. This would be a great cigar for those wanting to move up in strength without blowing them away. The only problem I've had is trying to keep it even. This is no big deal when the rest of the cigar is wonderful. Being very serious. This is a must try cigar for those who are true dedicated Pepin fans or you just love good cigars.
I believe this is a CI exclusive and a great cigar. There are a lot of good moderately priced cigars but you'd be hard pressed to find a better one than this.
Got a box of these and I had to try one asap, they are an excellent smoke.
Boy, there's a lot to like about this cigar. Got 5 of them in the Summer Sampler, smoked one, and then immediately bought a box. Flavors keep unfolding, with leather, cedar, earth and a floral component. Construction is incredible, but I've never seen a Pepin stick that wasn't well constructed. Nice, even burn all the way to the nub. I'm going to make sure I always have some of these around. By the way, if you're just starting to smoke fuller bodied cigars, this would make a great starter.
These are outstanding smokes! Full bodied, Cuban-esque, perfectly constructed. Vintage Pepin Garcia! The My Father juggernaut rolls out another gem!
Great smoke, one of his greatest! Highly recommend if your a full bodied smoker...
Just got one of these in my CI cigar of the month box. Puffin on it now and it just keeps opening up. I've read a v cut is recommended but I did a full guillotine cut and it's a wonderful. Will for sure be getting more of them!
Another winner from Pepin Garcia. Provides a mix of multiple flavors throughout the smoke, and is more medium or medium-full rather than other full-bodies Garcia blends (Tatuaje). One hint: have patience and do not smoke these as soon as they arrive off the truck. I did with the first stick and I actually told myself I wouldn't order them again. After trying another one after sitting in the humi for a couple of weeks, it delivered a totally different experience and moved onto my Garcia favorites list.
"To start I'm a Pepin fan all the way, so some bias is inevitable. As I wait to see if my $79 bid for a box of 20 churchills wins, I will tell my fellow enthusiasts that I have already smoked 4 5-packs of toro and robusto size sticks. For the price it is vintage DPG. It compares to DP Black, 5-Vegas Miami and a couple of Tatuaje lower end varieties. I love the cigar, it is bold enough with plenty of taste. Not a lot of change as it burns but no weakening either. While some required an extra flame a spot, the effort was a small price to pay. At these prices boys....jump on it. Smok'em if you got'em"
I am wiating for these Don Pepin legends and hope they are as good as their others.
Just bought a box these babies before cigar afficionado rates it and will be out of stock or double the price. anyways I would not say this is a full bodied cigar but it has enough punch not to be called a light weight either. this is definitely a full med to light full bodied cigar (if that makes sense) anyways since this is a pepin cigar as usual great product as expected right of the bat. Cuban style construction through and through. The wrapper is oily and reminds me of la requiza by tatuaje. Triple cap of course and flawless cuban wrapper perfect amount of tobacco means no soft nor hard parts on the cigar,
now lets talk about on how it smokes.. This cigar is a medium bodied cigar that reminds me of an aged cuban partagas. The burn was perfect all the way through even on a windy day when I smoked one. Lots of aged tobacco, leather, pepper and cedar although the strength profile never changed from start to finish, it was an extremely enjoyable cigar. The after taste reminds me of my cuban cigars as well. Once again pepin has done it again and created a future 90+ rated beauty, buy a box or two while you can still afford it.


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