text:
Chiefs coach is next
It is called "suspension mode".
It is about the suspension of coaches and this practice by PSL clubs looks set to gain momentum.
It's not funny!
In less than a week, two top PSL coaches have been suspended by their clubs for different reasons.
This trend is new to us and it is seen in some quarters as a "subtle" way of firing a coach. The old way of firing a coach was to "redeploy" him in the club, but this was just to frustrate the coach, who would later resign.
There was also a "tactful" way applied by clubs to force coaches to resign when supporters were not happy with the results.
They would simply be told that "as a club we can't guarantee your safety".
But now it's all about suspension.
Struggling Platinum Stars were the first to suspend their coach, Owen da Gama.
He is alleged to have solicited bribes from players for them to get game time.
These are damning allegations, of course, and Dikwena did well to appoint an independent investigation team to get to the bottom of the claims, which will shame the country if proven right.
But my beef is why should they suspend the coach? He should be seen as innocent until proven guilty.
The club argues that Da Gama may tamper with the investigations if he continues with his job.
But it's an open secret that Da Gama has been under tremendous pressure from the club, thanks to the side's abysmal run this season.
And this might have contributed to his suspension.
Rumours abound that former Orlando Pirates treble winner Ruud Krol will replace Da Gama after the Dutchman was seen taking notes during the Stars vs Pirates clash in Phokeng on February 22.
This was, however, vehemently denied by Stars' management.
But I believe it would have been prudent for the club to allow Da Gama to continue coaching under scrutiny, as investigations continue.
Removing him at this crucial time of the season could create instability and affect the mental steel of the players.
I don't think Da Gama is accused by the entire team in the "pay-to-play" allegations.
So surely the suspension of Da Gama will affect those who are loyal to him, those who are happy to play under him.
This, of course, is if the club still has faith in Da Gama.
Joining "Rubberdoll" on the sidelines was Bucs mentor Julio Leal.
Leal, who steered Pirates to an MTN8 and Telkom Knockout glory, was suspended on Monday after the Brazilian's admission to club supremo Irvin Khoza that Pirates were "too big" for him to guide.
I respect Leal for his frank admission but why should they suspend him , rather than show him the door?
I mean, the man has admitted that he has somehow run out of ideas for taking Pirates forward, unless he has not been honest in his admission.
Like Da Gama, Leal has been under pressure after the Buccaneers' embarrassing first-round exit from the African Champions League, humbled by Angolan side Recreativo de Libolo.
This is a difficult time for PSL coaches as they don't know who is next in line to be suspended.
I think club bosses should start to be honest with their coaches and stop lulling them into a false sense of security by being diplomatic with them when they are about to fire them. I hope other clubs don't follow this trend
yeah for me its heartless the manner in which our coaches have been suspended and fired.
V V had lots and lots of time... the clock is ticking we been behind him all the way
Yah neh kick backs in soccer yah corruption is everywhere....they should also suspend players who took part in this!
Have you ever heard of a person being precautionarily suspended? This is where you suspend a person in order to conduct investigations and have some assurance that they will not interfere with the fact finding processes. The type of allegations that Owen is facing are so cheap but yet can bruise the coach's reputation indelibly. If he were to be allowed to continue coaching, the complainant may then come back and pin further allegations of other sorts because remember, they still have to work together. This is why I find your take on this matter a bit myopic.
Secondly, I wonder if just one incident of suspending the coach warrants you to term the situation a new trend. I say one incident because you accept the enormity of the allegations against Owen and the repercussions they may have on our country (Not only Platinum Stars) if they are found to be true but yet you still want to assert that he should not have been suspended. Let us assume then, (and God forbid) that the allegations are true, do you honestly think that he will sit and let the investigations go ahead without any let or hindrance? Owen's suspension was a very judicious thing to do because and by your own admission, our reputation as a country is at stake.
Cox$pus! I will remember this name and who is Mcelwa Nchabeleng again?
Chiefs coach is next
Haahahhahaha!!! tomorrow's loss will be paving way for his suspension.


text:
Via the Dish, I read this hype-ridden piece on the "astonishing" progress of Google Translate, and this far more sober piece by Lance Ulanoff. Ulanoff writes,
"Initially… the translation was perfect, but when I started to speak in longer sentences, it basically fell apart and got a lot of it wrong. As I tested with others who spoke in Greek, German and French, we noticed the same thing. We could never completely rely on Google translate to get the words right."
This is, I think, a constant dynamic in tech circles: astonishment, followed by growing dissatisfaction and frustration. So what makes machine translation difficult?
I could go on about these issues forever. (Put a beer in me and I'll talk your ear off about why both the Chomskyan approach and the Peter Norvig approach are at an impasse when it comes to actually decoding language as a system.) Let's pick one particular issue for true machine translation: the dilemma put forth by Terry Winograd, professor of computer science at Stanford. (I first read about this in this fantastic piece on AI by Peter Kassan.) Winograd proposed two sentences:
The committee denied the group a parade permit because they advocated violence.
The committee denied the group a parade permit because they feared violence.
There's one essential step to decoding these sentences that's more important than any other step: deciding what the "they" refers to. (In linguistics, we call this coindexing.) There are two potential within-sentence nouns that the pronoun could refer to, "the committee" and "the group." (Note that both are singular and "they" is plural, so one thing machine translation has to overcome is problems with formalist grammar!) These sentences are structurally identical, and the two verbs are grammatically as similar as they can be. The only difference between them is the semantic meaning. And semantics is a different field from syntax, right? After all, Chomsky teaches us that a sentence's grammatically is independent from its meaning. That's why "colorless green ideas sleep furiously" is nonsensical but grammatical, while "gave Bob apples I two" is ungrammatical and yet fairly easily understood.
But there's a problem here: the coindexing is different depending on the verb. In the first sentence, a vast majority of people will say that "they" refers to "the group." In the second sentence, a vast majority of people will say that "they" refers to "the committee." Why? Because of what we know about committees and parades and permitting in the real world. Because of semantics. A syntactitian of the old school will simply say "the sentence is ambiguous." But for the vast majority of native English speakers, the coindexing is not ambiguous. In fact, for most people it's trivially obvious. And in order for a computer to truly understand language, it has to have an equal amount of certainty about the coindexing as your average human speaker. In order for that to happen, it has to have a theory of the world, and that theory of the world has to not only include understanding of committees and permits and parades, but apples and honor and schadenfreude and love and ambiguity and paradox….
Some might say that this is a particularly bad example to pick with Google Translate, because it is a probablistic engine; rather than trying to parse the syntax-semantics interface for these sentences, it would merely see how these sentences or parts of sentences have been translated in the past, assign a certain probability to a given set of translations being correct, and act accordingly. (In terms of pure translation, anyway, it would only have to faithfully provide an equivalent language-specific reading of the English text to speakers of other languages, but I'm afraid in some languages that would entail having to coindex the pronoun itself.) That's true– but it's precisely that probabilistic nature, that reliance on chance, that leaves Ulanoff and his partners frequently unable to understand each other past a certain level of complexity. In order to do that — in order to go from pretty good to legitimately astonishing — I believe machine translation would have to move beyond Bayesian probabilistic approaches and towards developing an actual theory of the world for their models, which would entail a functioning theory of mind. Outside of Doug Hofstadter, hardly anyone is even trying to do that. (As my friend Alex Waller says, "It's okay to discuss the pros and cons of AI, but we need to admit actual AI will almost certainly not exist in our lifetimes.") So for now we'll have to settle for OK and recognize that there's always going to be the odd WTF awful translation popping up, because of what the human language capacity can do and computers can't.

subset: commoncrawl


text:
The Second Opinion
Exchange Watch
Why were Massachusetts reporters slow to probe the health exchange meltdown?
Q&A with a Boston IT expert who pieced together the story in a 31,000-word 'Autopsy Report'
By Trudy Lieberman Sep 17, 2014 at 02:50 PM
As Massachusetts goes, so goes the nation--at least when it comes to healthcare. In 2009 and 2010, in the midst... More
If it sounds 'too good to be true…'
How Health News Florida flubbed the rate story last week and what all reporters can take away from it
By Trudy Lieberman Jul 2, 2014 at 04:00 PM
Remember those seven tips I offered earlier this month for how to report on health insurance rate proposals? I have... More
Sticking with Washington's 'whistleblower judge flap'
Puget Sound Business Journal's Valerie Bauman reported the heck out of a state insurance commission saga—and the broader issue of narrow networks
By Trudy Lieberman Jun 23, 2014 at 06:50 AM
There are different ways to tell the story of what's happening with Washington's insurance exchange, a state marketplace called... More
Oregon reporters missed the story of a failing health exchange—until they didn't
After a slow start, the state press corps recovers with a bang
By Trudy Lieberman May 5, 2014 at 11:15 AM
Behind Oregon's failed health insurance exchange is a story of spin that in some ways mirrors federal officials' management of... More
What coverage of New York's 'surprise billing' fix left out
The fight between doctors and insurers is an important one to keep watching
By Trudy Lieberman Apr 9, 2014 at 11:00 AM
Last week, The New York Times ran an article announcing a significant healthcare provision in the budget deal reached by... More
Got health coverage? Prove it!
How widespread are proof-of-coverage problems? Fort Myers News-Press took an extra step to find out.
By Trudy Lieberman Jan 30, 2014 at 10:50 AM
If insurance exchange shoppers thought their trials would necessarily end once they were--finally--able to log on and do the hard... More
Exchange Watch: Missing doctors, missing coverage
In New York, insurance exchange shoppers (if not enough reporters) discover the lack of out-of-network benefits
By Trudy Lieberman Dec 18, 2013 at 02:50 PM
At the tail end of October, when the media were hyper-fixated on the woes of HealthCare.gov and who knew what... More
Better late than never: the new insurance sticker shock story
The press discovers high cost sharing, but the story goes deeper
By Trudy Lieberman Dec 13, 2013 at 11:00 AM
As coverage of the Affordable Care Act rolls along, the pesky subject of high out-of-pocket costs for plans purchased on... More
Exchange Watch: Telling half a story about the federal exchanges
Politico sniffs out the White House spin
By Trudy Lieberman Sep 30, 2013 at 02:50 PM
We can probably forgive Secretary of Health and Human Services Kathleen Sebelius for spinning tomorrow's debut of Obamacare in the... More
Exchange Watch: Florida
There's been solid coverage in the Sunshine State. Now it's time to treat Obamacare like the consumer story it is
By Trudy Lieberman Sep 20, 2013 at 11:45 AM
What can we say about Florida, that bad boy of healthcare reform? Every time states are supposed to do something... More
Exchange Watch: Missing in Montana
The Associated Press trips up in covering an Obamacare rate announcement
By Trudy Lieberman Aug 23, 2013 at 06:57 AM
While it was good to see the AP's statehouse reporter do a story this week on the release of... More
Exchange Watch: Nevada
Who's sending out those press releases? Brokers, too, have an angle on Obamacare.
By Trudy Lieberman Aug 20, 2013 at 03:30 PM
A few days ago Dennis Myers, the news editor of the Reno News & Review, sent along a press... More
Exchange Watch: Are New Yorkers getting a bargain?
The state announces a big win on health policy prices, but a closer look is in order
By Trudy Lieberman Jul 18, 2013 at 11:02 AM
Hallelujah! New York's insurance exchange--kept under wraps for months by the administration of Gov. Andrew Cuomo--has finally brought forth... More
Exchange Watch: California Dreaming
Low healthcare premiums on the West Coast were trumpeted as a big, good-news Obamacare story. But: "Compared to what?"
By Trudy Lieberman Jun 5, 2013 at 06:51 AM
In mid-May, The Spokesman-Review in Spokane trumpeted some good news for Obamacare, reporting that "Health insurance next year will cover... More
Exchange Watch: half a story in Connecticut
On insurance affordability, the Hartford Courant falls short
By Trudy Lieberman Mar 8, 2013 at 02:58 PM
This is the second in a series we're calling Exchange Watch, which will keep an eye on the rollout of... More
Exchange Watch: growing pains in Connecticut
Is the state's model insurance plan unaffordable?
By Trudy Lieberman Feb 19, 2013 at 10:59 AM
On October 1, state health insurance exchanges throughout the country, called Health Insurance Marketplaces, will start enrolling people eligible... More
New survey reveals everything you think about freelancing is true - Data from Project Word quantifies challenges of freelance investigative reporting
Why one editor won't run any more op-eds by the Heritage Foundation's top economist - A reply to Paul Krugman on state taxes and job growth made some incorrect claims
Why we 'stave off' colds - It all started with wine
The New Republic, then and now - Tallying the staff turnover at the overhauled magazine
Why serious journalism can coexist with audience-pleasing content - Legacy media organizations should experiment with digital platforms while continuing to publish hard news
Why Bill O'Reilly can play hardball on his war zone story (5)
Why scientists often hate records requests (4)
Showdown over the future of independent documentaries at PBS (2)
The LA Times goes deep on superbug outbreak (2)
Email blasts from CJR writers and editors
The rise of feelings journalism (TNR)
"Bloom engaged in an increasingly popular style of writing, which I've discussed on my blog before, which I call "feelings journalism." It involves a writer making an argument based on what they imagine someone else is thinking, what they feel may be another person's feelings. The realm of fact, of reporting, has been left behind."
Things a war correspondent should never say (WSJ)
"The correspondent retelling war stories surely knows that fellow correspondents had faced the same dangers or worse"
The joyful, bloody media circus of bringing down Brian Williams (Bloomberg)
"In the media, we eat our own for sport"
On WaPo trying to interview a cow (National Journal)
"'I wasn't milked on the White House lawn by a strange man,' The Washington Post—the venerable institution that would later come to break the Watergate scandal and win 48 Pulitzers—quoted her, a farm animal, as saying"
Greg Marx discusses democracy and news with Tom Rosenstiel of the American Press Institute
CJR's Guide to Online News Startups
ACEsTooHigh.com – Reporting on the science, education, and policy surrounding childhood trauma
Who Owns What
The Business of Digital Journalism
A report from the Columbia University Graduate School of Journalism
Questions and exercises for journalism students.
Hey millionaire tech bros: Have patience with the editorial process – Chris Hughes probably wanted to enable great journalism at first. Then the dust settled and before you know it, he's shaking everything up again
ESPN's The Undefeated off the ground – Jason Whitlock's long delayed race and sports site launches first story


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Skype translation service rolls out in preview form
Chatting with someone of a different language can be a daunting task, but technology is bridging the language barrier daily. Google has their translation service, which serves as a robust tool for travelers, but what about calls? Skype has begun testing their own translation features on Windows 8.1. Not only for voice calls, Skype will have translation available for video chats as well. The features are still in testing, and Microsoft is looking for brave (hopefully bilingual, we're sure) folks who are willing to help it along.


text:
Want travel alerts for this area?
Enter your name and email to receive alerts when new vacation deals are added to any property in this region.
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Showing 1-1 of 1 Family Reunion Resorts
Paradise Cove Marine Resort
Afton, Oklahoma, United States
Treat your entire family to a fun-filled reunion along the banks of Grand Lake. Spend your days soaking up the sun on the beach, or swim out to the in-lake WaterMat. Boat and wave runner rentals are available, or you can cast a line into some of the most bountiful fishing waters in the area! Two- and three-bedroom condos will provide enough... more
- Wifi
- Restaurant Onsite
- Pets Allowed
- Property Size 12 units
- Conference Facility
- Kids Allowed
- Nearby City Grove
- Nearby Water Grand Lake
- Open Dates All Year
- Beach
- Family
- Golf
- Reunions
- Wedding
- Fishing
- Romantic
- Lake
- Honeymoon
- Villas and Condos
Showing 1-1 of 1 Family Reunion Resorts


text:
Multiple Pages, 1 CSS File
# March 20, 2013 at 4:08 pm
Hey guys so I am new and learning HTML and CSS now. I am use to incline css but I am building a website which has 5 webpages incorporated into it and I need to use 1 external CSS file to make each of the 5 html pages look different but I am having a hard time figuring out how to do this.. I was hoping you guys can help..
ThankS!# March 20, 2013 at 4:23 pm
Make sure to give each different template a unique body class:
Then in your CSS you can override default styles *or* add styles specific to a page by going:
.page-name .other-selector { /* styles */ }
.page-name .parent .child { /* styles */ }
Or, if you're using the wonderful world of SASS/SCSS you can do something like this:
.page-name {
.other-selector { /* styles */ }
.parent p { /* styles */ }
}# March 20, 2013 at 5:18 pm
when ever i add it seems to cancel out my javascript css..
#smenu {background-color:#ffffff; text-align:center; border:1px solid #000099; z-Index:999; visibility:hidden; position:absolute; top:100px; left:-225px; width:250px;}
#sleft {width:220px; float:left;}
#sright {width:20px; float:right;}
#sright a:link{text-decoration:none; color:#999999; font-weight:bold; font-family:arial, helvetica, sans-serif;}
#sright a:visited{text-decoration:none; color:#999999; font-weight:bold; font-family:arial, helvetica, sans-serif;}
#sright a:active{text-decoration:none; color:#999999; font-weight:bold; font-family:arial, helvetica, sans-serif;}
#sright a:hover{text-decoration:none; color:#999999; font-weight:bold; font-family:arial, helvetica, sans-serif;}
#hovmenu {background-color:#ffffff;border: 1px solid #000000; text-align:center;z-Index:999; visibility:hidden; position:absolute; width:200px;}
#menu {display:none;}
.index {
width: 400px;
background: gray;
}# March 20, 2013 at 5:33 pm
i have this on the site:
What Are Your Favorite Countries?
and In the css file i am trying to have them centered on the page in Italic.# March 20, 2013 at 5:37 pm
For starters, if you are listing items like that, you should probably use an unordered list:
If you want the text centered, you could do this with your CSS:
.country-list {
list-style: none;
text-align: center;
But like I said, these are *super* basic things that are covered early on in any tutorial on CSS and HTML.
You must be logged in to reply to this topic.


text:
Exeter Coffee Table Set
$ 169.99
Less is more with the Exeter coffee table set. The glass tops enhance the open and airy feeling you're going for—while the metal tubular frames in a rustic two-tone finish inject a highly contemporary vibe. Includes coffee table and two matching side/accent tables.
44"W x 22"D x 16"H
QUESTIONS?Call us at 631-768-8130 (open 10am-6pm) or
drop us a message here.
Product Specification
Style - Contemporary
Material - Glass


text:
10 Easy Sugar Scrub Recipes for Winter Skin
by Becky Striepe
Is the chilly winter weather wreaking havoc on your skin? Instead of buying expensive scrubs to exfoliate and moisturize, try these DIY Sugar scrub recipes that you can make yourself on the cheap!
My skin takes a beating in the winter, and I'm sure I'm not the only one. All of that cold wind and dry air makes my skin dry and sometimes even painfully cracked. A sugar scrub is such a great, natural way to help your skin bounce back, and when can make your own DIY sugar scrubs, you can enjoy those benefits even on a Dollar Store budget!
- Foot Scrub - This recipe from Wellness Mama uses only two ingredients for smooth, healthy feet all winter long.
- Face and Body Scrub - This scrub has very little oil, so you can even use it on your face without worrying about breakouts.
- Easy Peasy Sugar Scrub - You can customize this moisturizing scrub using any scent that you want!
- Warming Face Scrub - Sooth your poor face with this coconut oil scrub.
- Sugar Cube Scrubs - This recipe uses a mold to turn your sugar scrub into cute little sugar cubes!
- Lavender Sugar Scrub - Decompress from holiday stress and treat those aching muscles right!
- Coconut Lime Sugar Scrub - It's like a beach vacation in a jar!
- Pumpkin Sugar Scrub - This scrub uses real pumpkin, and it sounds good enough to eat with a spoon.
- Lemon Sugar Hand Scrub - Do your hands get dry and cracked in the winter? There's a scrub for that!
- Peppermint Candy Cane Sugar Scrub - Don't you love the pretty colored layers in this scrub? And they use a surprising natural alternative to food coloring to give the red layer its vibrant hue!


text:
The face of survival? It had a black eye, a missing tooth and 13 stitches in its mouth. It took an elbow to the nose Friday, got knocked to the floor and even stood bruised-face-to-face with Toronto's DeMarre Carroll in a staredown.
The face of survival came with a tortured smile, though. Goran Dragic flashed it after hitting a corner shot to stretch the second-half lead in the Heat's 103-91 win in Game 6 of this bar fight of a playoff series with Toronto.
Dragic ran down the court, waving for the home crowd to pump the volume, showing exactly how he felt on the way to a career playoff high of 30 points. It's how all the Heat felt.
That's all that matters,...


text:
Sports Briefs
Minot salvages split in St. Cloud
ST. CLOUD, Minn. – The Minot Vistas managed a doubleheader split Monday, losing their first game before rebounding with a win in the nightcap.
Minot battled the St. Cloud Chutes – the seventh-ranked team in Minnesota – in the opener, losing 8-5. Leading 2-0 after two, the Chutes tacked on an extra six runs in the third to put the game out of reach for the Vistas with Chandler Jacob picking up the loss.
Grant Larson provided a late spark for Minot in the seventh, blasting a three-run home run as part of a four-run inning.
The Vistas responded with a three-run victory of their own in Game 2, a 7-4 win over the St. Cloud 76ers.
Larson was the only Minot player to register multiple hits, going 2-for-2 with two RBIs.
Minot travels to Woodbury today for a 6 p.m. game against East Ridge.
-Daily News Staff


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The mouse genome database (MGD, ), the international community database for mouse, provides access to extensive integrated data on the genetics, genomics and biology of the laboratory mouse. The mouse is an excellent and unique animal surrogate for studying normal development and disease processes in humans. Thus, MGD's primary goals are to facilitate the use of mouse models for studying human disease and enable the development of translational research hypotheses based on comparative genotype, phenotype and functional analyses. Core MGD data content includes gene characterization and functions, phenotype and disease model descriptions, DNA and protein sequence data, polymorphisms, gene mapping data and genome coordinates, and comparative gene data focused on mammals. Data are integrated from diverse sources, ranging from major resource centers to individual investigator laboratories and the scientific literature, using a combination of automated processes and expert human curation. MGD collaborates with the bioinformatics community on the development of data and semantic standards, and it incorporates key ontologies into the MGD annotation system, including the Gene Ontology (GO), the Mammalian Phenotype Ontology, and the Anatomical Dictionary for Mouse Development and the Adult Anatomy. MGD is the authoritative source for mouse nomenclature for genes, alleles, and mouse strains, and for GO annotations to mouse genes. MGD provides a unique platform for data mining and hypothesis generation where one can express complex queries simultaneously addressing phenotypic effects, biochemical function and process, sub-cellular location, expression, sequence, polymorphism and mapping data. Both web-based querying and computational access to data are provided. Recent improvements in MGD described here include the incorporation of single nucleotide polymorphism data and search tools, the addition of PIR gene superfamily classifications, phenotype data for NIH-acquired knockout mice, images for mouse phenotypic genotypes, new functional graph displays of GO annotations, and new orthology displays including sequence information and graphic displays.
The mouse genome database (MGD) is a comprehensive, integrated system for exploring genetic, genomic and biological information for the laboratory mouse (1–3). MGD facilitates the study of human biology and disease by supporting the mouse as an exquisite model system and enables hypothesis generation through its integration of diverse data and use of semantic standards. Core data include sequences, maps, genes, gene function, gene families, strains, mutant phenotypes, disease models, mammalian orthologies, single nucleotide polymorphisms (SNPs) and other polymorphisms (Table 1). Data are integrated through a combination of expert human curation and automated processes that determine object identities and shared relationships and use a variety of controlled/structured vocabularies (ontologies), including the Gene Ontology (GO), Mammalian Phenotype (MP) Ontology, Anatomical Dictionary for Mouse Development, OMIM, InterPro and PIR super families. Collaborative efforts with other large genome informatics resources increase data accuracy through joint curation to resolve inconsistencies. MGD provides authoritative data for the research community on nomenclature for mouse genes, alleles, and strains, and GO annotations for mouse gene function. MGD also is the hub for mouse phenotype information, providing robust access to phenotypic data for human users and for computational applications.
|MGD data statistics
|October 2, 2006
|Number of genes with sequence data
|27 906
|Number of genes (including uncloned mutations)
|30 893
|Number of markers (including genes)
|57 375
|Number of markers mapped
|55 326
|Number of genes with protein sequence information
|20 247
|Number of genes with GO annotations
|17 304
|Number of mouse/human orthologies
|15 672
|Number of mouse/rat orthologies
|14 758
|Number of genes with one or more phenotypic alleles
|Number of cataloged phenotypic alleles
|16 416
|Number of references
|107 170
|Number of RefSNPs
|6 348 628
|Number of mouse nucleotide sequences integrated into the MGI system (includes ESTs)
|>8 400 000
|MGD data statistics
|October 2, 2006
|Number of genes with sequence data
|27 906
|Number of genes (including uncloned mutations)
|30 893
|Number of markers (including genes)
|57 375
|Number of markers mapped
|55 326
|Number of genes with protein sequence information
|20 247
|Number of genes with GO annotations
|17 304
|Number of mouse/human orthologies
|15 672
|Number of mouse/rat orthologies
|14 758
|Number of genes with one or more phenotypic alleles
|Number of cataloged phenotypic alleles
|16 416
|Number of references
|107 170
|Number of RefSNPs
|6 348 628
|Number of mouse nucleotide sequences integrated into the MGI system (includes ESTs)
|>8 400 000
MGD data available via the website are updated daily. MGD exchanges data with genome resources such as NCBI and UniProt weekly. Software releases that occur as projects are completed, generally 4–6 times annually. A recent snapshot of MGD content is shown in Table 1. MGD continues to evolve, expanding its data coverage, improving data access, and providing new data query, analysis and display tools. Computational users and genome centers can access MGD data through daily file reports available via FTP and through direct SQL.
MGD is a core component of the Mouse Genome Informatics (MGI) database resource () hosted at The Jackson Laboratory (). Other projects and resources that are part of the MGI system include the Gene Expression Database (GXD) () (4) and the Mouse Tumor Biology (MTB) Database () (5). All MGI component groups participate actively in the development and application of the GO () (6).
Mouse SNPs integrated in MGD
Mouse SNPs have been incorporated into MGD. A comprehensive summary report is provided that gives an overview of SNP numbers by strain, by chromosome and by SNP data submitter (). Users can query for SNPs by strain, strain comparisons, SNP attributes (variation type and functional class), map position, marker range, or by association to MGD genes and genetic markers. Output can be customized, for example to display SNPs among strains or SNPs showing only differences compared to a specific strain. A tab-delimited output option is available for visualizing presumptive haplotype blocks. Figure 1A displays output searching for a simple search of all SNPs detected for the Fgf1 gene. For each SNP, the nucleotide present at each site for each strain is given, color-coded by nucleotide. Links are provided to a MGI SNP Detail page (Figure 1B), as well as to the Mouse Phenome Database (MPD), NCBI's dbSNP database and to the MGI Gene Detail page for the gene in which the SNP is detected.
Protein Superfamily Vocabulary Browser
For locating links between MGD mouse genes and the protein classes, MGD now incorporates UniProt PIRSF (Protein Information Resource Superfamily) protein classifications into a Protein Superfamily Vocabulary Browser (). Figure 2 shows a protein superfamily detail page for the pepsin genes, listing the mouse superfamily members and any human and rat orthologs. Options on this page also provide users the opportunity to download available sequences in FASTA format or forward them to the MouseBLAST tool.
Phenotype data for NIH-acquired knockout mice
In 2006, the NIH reached an agreement that has allowed the distribution of mutant mice and frozen embryos from two private collections of knockout mice developed by Deltagen, Inc., and Lexicon Genetics, Inc. The data characterizing and phenotyping these animals have been deposited with MGD and are available through our web interface (WI). By integrating this phenotype data with MGD, users can search simultaneously for all phenotype data, regardless of its source. A list of these NIH-acquired mutants can be found at ; to search all phenotypes in MGD, use the phenotype search form at .
Images of phenotypic genotypes of mice
MGD now adds image data to phenotypic descriptions of mutant genotypes whenever available. Although current images focus on visible external phenotypes, such as pigmentation changes, limb, eye, or ear abnormalities, and coat texture, future images will also include histology, pathology, x-rays and whole animal imaging. Figure 3 shows an allele record for Mregdsu (the dilute suppressor allele of the melanoregulin gene) with a thumbnail representative image in the allele page and a link to additional images available for this phenotypic mutant.
Graph representation of GO annotations
MGD now provides an additional way to view functional (GO) annotations of genes. Previously, GO annotations were available in a standard tabular form and as computer generated text paragraphs. This year we have added a graphical view, where users can view the path from the term annotated, up the GO graph to the root terms (molecular function, cellular component and biological process) (Figure 4). This view allows users to visualize how terms are related and the granularity of the particular GO annotations.
Enhanced mammalian orthology reports
The display of mammalian orthology has been enhanced to include a primary nucleotide and protein sequence for each ortholog and the ability to download these sequences as FASTA files or to forward them to the MGD MouseBLAST tool. In addition, new links are provided to VISTA homology plots, HomoloGene and to MGD's new mouse–human–rat comparative GO graph (Figure 5).
MIT marker files and genome coordinates
MIT markers are commonly used STS markers, particularly for mapping QTL (quantitative trait loci). MGD now provides the original files from the Broad Institute (formerly the Whitehead Institute at MIT) including marker name, assay, primers and full assay sequences. In addition, genome coordinates for all MIT markers are available, thus making these markers accessible for searching the mouse genome assembly.
Electronic publication
We now have posted an electronic publication of Origins of Inbred Mice edited by Herbert C. Morse III. This out-of-print book, originally published in 1978, provides an historical perspective on the development of inbred mice. It is thoroughly indexed and linked to appropriate terms in MGD. This book joins other out-of-print classics of mouse genetics in electronic publication at MGD.
Mouse gene, allele and strain nomenclature
The MGD gene annotation group assigns unique symbols and names to mouse genes, alleles and strains following the guidelines set by the International Committee on Standardized Genetic Nomenclature for Mice (). The official nomenclature for mouse genes, allele and strains is becoming widely disseminated through regular data exchange and curation of shared links between MGI and other bioinformatics resources, and increasing adherence of journal publications to nomenclature standards. The MGI nomenclature group works closely with nomenclature specialists for human () and rat () to provide consistent nomenclature for mammalian species. The mouse and human nomenclature committees collaborate with scientific experts in specific domain areas to develop a systematic nomenclature for those genes that should be grouped together in a family, such as the ARID family (7) or to revise the nomenclature for an already established gene family, such as the ACOT family (8). Scientists can contact the MGD nomenclature coordinator by email (email@example.com) and can reserve symbols prior to publication using the electronic nomenclature submission form ().
Electronic data submission
Any type of data that MGD maintains can be submitted as an electronic contribution. Over the last year, the most frequent submissions have been of mutant and phenotypic allele information originating with the large mouse mutagenesis centers and repositories that contribute data sets to the International Mouse Strain Resource (IMSR, ) (9). Other common types of submission include mutant and QTL mapping data. Each electronic submission receives a permanent database accession ID. All data sets are associated with their source, either a publication or an electronic submission reference. MGD reference pages provide links to associated data sets. On-line information about data submission procedures is found at .
Community outreach and user support
MGD provides extensive user support through on-line documentation and easy email or phone access to User Support Staff.
User Support can be accessed by:
Email access: firstname.lastname@example.com
Telephone access: +1 207 288 6445
FAX access: +1 207 288 6132
Other outreach
MGI-LIST () is a moderated and active email bulletin board supported by the MGI User Support group.
Here, we summarize the high level functionality of the major components of the system. At the heart of MGD is the database itself. MGD is implemented in the Sybase relational database management system. Its ∼180 tables form the core within which the biological information is stored. Additional sequence data such as BLAST-able databases and genome assembly files are stored outside the relational database. There are two primary vehicles by which data are entered into MGD: the editing interface (EI) and automated load programs. The EI is an interactive, graphical application. Curators use the EI to enter new data from the literature, to verify the results of automated loads and to correct errors. The automated load programs integrate larger data sets from many sources into the database. Automated loads involve quality control (QC) checks and processing algorithms that integrate the bulk of the data automatically and identify issues to be resolved by curators or the data provider. Through these two vehicles, the EI and automated loads, we are able to acquire and integrate large amounts of data into high-quality, curated information.
There are several different routes for public data access. The WI is the main tool allowing users to query interactively and display our data through a web browser. MouseBLAST allows users to do sequence similarity searches against a variety of rodent-relevant sequence databases that are built weekly from selected sequence databases from NCBI, UniProt and other providers. Mouse GBrowse allows users to visualize mouse data sets against the genome as a series of linear tracks. Supplementing these three interactive tools is a large collection of public database reports generated nightly. These reports provide concise listings of large subsets of data, for example, all mouse/human homologies. They are a major source for other data providers who link to or use MGD data in their products and for computational biologists who use MGD data in their analyses. Direct SQL access to the database is available for sophisticated users who wish to construct custom queries or to perform analyses not possible through the WI. Finally, we are developing a web services API that will provide another programmatic route into MGD.
For a general citation of the MGI resource, please cite this article. In addition, the following citation format is suggested when referring to datasets specific to the MGD component of MGI: mouse genome database (MGD), MGI, The Jackson Laboratory, Bar Harbor, Maine (URL: ). [Type in date (month, year) when you retrieved the data cited.]
The Mouse Genome Database is supported by NIH/NHGRI grant HG000330. Funding to pay the Open Access publication charges for this article was provided by The Mouse Genome Database.
Conflict of interest statement. None declared.


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Story URL: http://news.medill.northwestern.edu/chicago/news.aspx?id=198558
Story Retrieval Date: 4/17/2015 12:24:30 PM CST
In New York City, Manhattan's Asians are being forced out of Chinatown by the steep rise in property values. The story is different in Chicago's Chinatown, where the aging, stable population is being augmented by an influx of new residents.
The population has increased by more than 24 percent, to 7,254, in the last decade.
"There is a constant and likely increasing number of immigrants moving into the community," said Theresa Mah, policy consultant with the Coalition for a Better Chinese American Community,a group based in Chinatown that works to empower Chinese and Chinese-American Chicagoans.
Mah said her group defined a "Greater Chinatown Community Area" for a
more accurate understanding of the demographics. That area encompasses parts of
Armour Square, Bridgeport, McKinley Park and Brighton Park.
"The Asian population in this area is about 27,000, and perhaps 90 percent are Chinese," Mah said.
In Chinatown itself, the population increase is driven by immigrants.
These immigrants are young and old, and most of them have relatives who
already live in Chinatown, according to Sylvia Wu, principal of Chinatown's Pui
Tak Christian School.
"Relatives bring them over and want them to be nearby," Wu said. "They bring young people here for job opportunities and grandparents to take care of their children."
Another reason immigrants are attracted to Chinatown is low English proficiency.
Mah said with increasing number of immigrants, there will be more needs for ESL
classes, bilingual social services and education.
"New immigrants continue to see this area as a port of entry," Mah said. "Because it is close to jobs that they can get without English skills, social services through the long-established agencies in the community and good public transportation that serves the area."
All of those conditions are true about New York, but Mah said the housing issue is the big difference between the two Chinatowns and what is happening in each.
In Chicago, families can choose to stay in the area in newer and more
spacious homes or condos, or live in adjacent areas where there are houses
within reach financially.
"New York has seen its population move out to the suburbs," Mah said. "Manhattan is expensive and space is limited. In Chicago, in contrast, there has been a great deal of residential development over the past 10 years or so."
Another Chinatown resident, who wouldn't give his name and spoke only in Chinese, said employment stability is the reason most residents continue living here.
"Most of the residents have a stable job in or near Chinatown," said the man, Mr. Sun, who was at a closed community center.
Another reason, he said, is that "senior citizens have good welfare, so they
don't have to move to cheaper apartments."
Even though high housing costs aren't squeezing out Chicago residents, and the community is relatively stable, Chinatown is not without its demographic problems.
The aging population and the economic downturn are both taking a toll.
According to the 2010 Census, Chicago Chinatown's median age is 42.4 and that of Asian alone is 43.9. In the city of Chicago as a whole, by comparison, the median age is 32.9.
"There is a disproportionate number of seniors in this area," Mah said. "Thirty-three percent of the population is over 55 in the Armour Square Community Area compared to the national average of about 20 percent."
Many residents, however, see the aging problem as an opportunity for the young.
"Most of the stores here are family businesses," said Javien Chen, director of national sales and marketing at Nexus Holidays, a travel agency in Chinatown. "So the younger generation will take over the business sooner or later. [Businesses] will always hire young people."
Under the economic downturn, however, it is harder for those small-business owners to survive.
"From our observation, some small stores are closed," Chen said. "And there isn't increasing traffic."
But Wu dismissed that as a concern. She said restaurants, the staple of Chinatown's economy, have maintained consistent.
"Weekends are the busiest time," Wu said. "There are a lot of visitors and the restaurants are crowded all the time."
Chen said Chinatown needs more marketing to promote business, rather than being content with consistency.
Dustin Harrington, a Chicago resident who visited Chinatown Friday with his friends for the first time, said Chinatown needs advertisement, such as tours.
"The reason I didn't come here before," he said, "is that I had no one to show me around."


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text:
Do you want to make Ohio.com your homepage?
By Aoife White and Angeline Benoit
Bloomberg News
FILE- In this April 17, 2007 file photo, exhibitors of the Google company work on laptop computers in front of an illuminated sign of the Google logo at the industrial fair Hannover Messe in Hanover, Germany. Googles removal of search results in Europe is drawing accusations of press censorship, as stories from some of the continents most prominent news outlets begin vanishing. The U.S. Internet giant said Thursday it is getting 1,000 requests a day to scrub results. The U.S. firm must comply with a May ruling from the European Unions top court that enables citizens to ask for the removal of embarrassing personal information that pops up on a search of their names. Among links to vanish were stories on a soccer referee who resigned after a scandal in 2010, French office workers making post-it art, a couple having sex on a train and a lawyer facing a fraud trial. At least three British media, including the Guardian newspaper and public broadcaster BBC, said Google notified them search results in Europe woul
Click here to read or leave a comment(s) on this story.
If you live in the Akron area, the Rev. Ronald Fowler is a name you probably know well.


text:
It involves about 5 minutes of prep—and it's impossible to dislike.
You might as well make a double batch of this sweet-and-salty, double-coconut popcorn—you'll need it.
You don't have to use a vegan chocolate to make this decadent tart—any bittersweet baking bar will be great.
Local chefs run off with all the fancy lettuces at your farmers' market? Not to worry. The herbed avocado base of this dish will elevate even the most basic supermarket greens.
A beautiful winter-white salad; the natural bitterness of the endive is balanced by sweet roasted parsnips and a tad of sugar in the dressing.
A vegan's delight, with a gentle bonus buzz from the matcha.
This mixture gets pretty sticky in the food processor. Don't be alarmed if you have to scrape and pulse and scrape and pulse to keep the machine moving.
An unexpected way to revamp hot chocolate.
The ultimate do-ahead, portable power breakfast; it's also great with fresh fruit.
Use a frozen whole grain waffle, or freeze leftover homemade waffles between sheets of waxed paper.
These wings are hot, sweet, and tangy.
A new restaurant trend, these grain, nut, and seed clusters add a satisfying crunch and healthy hit to salads, veggies, and more.
No matter how fanatical you are about straining the milk, some sediment will settle as it sits. Shake or stir before using.
Watermelon's natural sweetness gets a little boost from agave syrup instead of refined sugar in this refreshing summer beverage.
A warming drink with echinacea, plus a kick of ginger and cayenne to clear the sinuses? We're in.
Spoon this spicy and acidic kimchi relish over a steak salad, serve alongside pan-fried chicken, or try it on a taco.
Tired of the same old yogurt for breakfast? This blackberry smoothie recipe keeps things interesting (yet healthy!).
This healthy fruit smoothie recipe is packed with peaches, grapefruit, orange, banana, and strawberries. But any fruit you have on hand will work, too.
Food Innovation Group: Bon Appétit and Epicurious
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