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A concert at Mali's National Museum
Dr Geoff Baker from the Department of Music at Royal Holloway, University of London will travel to Cuba in March 2012 for the second phase of a research project he's Co-investigator on. Led by Dr Lucy Durán (SOAS, University of London) 'Mali-Cuba: Music Across Generations' is a unique project that celebrates two great musical cultures and their deep historical and cultural connections, through the musicianship of young children.
The project emerged from 'Growing into Music', a three-year AHRC-funded research project that explored children's acquisition of musical skills and knowledge in India, Rajasthan, Azerbaijan, Mali, Guinea, Venezuela and Cuba. 'Mali-Cuba: Music Across Generations' looks specifically at common musical ground between Mali and Cuba, and has the UK label World Circuit Records as its business partner.
Dr Baker says: "The project aims to bring the results of our research to wider audiences as well as back into the communities themselves where we have been working." He adds: "It seeks to stimulate the transfer of musical skill and knowledge across generations, and to enable first-hand – and first-time – musical encounters between talented children from Mali with those from Cuba."
The first phase of the project which took place in Mali in January 2012 was a great success – the highlight being a concert performed by 30 children that opened the 2012 series of Musical Thursdays, sponsored by Mali's National Museum in Bamako.
The researchers are currently into the second phase of the project, taking place in Cuba until 1 April 2012. Dr Baker, Dr Durán and project assistant Michele Banal will be joined by four of the most talented young griots from Mali, under the musical guidance of virtuoso balafon player and one of Mali's leading musicians, Lassana Diabaté. Dr Baker comments: "None of the Malian musicians have ever left Mali before. They'll be meeting their equivalents, the talented Cuban children we've been working with. Together, they will participate in a series of events and exchange musical ideas and knowledge."
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Grant Details
|Grant Number:
|5R21CA117261-02 Interpret this number
|Primary Investigator:
|Mathews, Herbert
|Loyola University Chicago
|Project Title:
|Immune Dysregulation By Psychosocial Distress
|Fiscal Year:
DESCRIPTION (provided by applicant): Diagnosis of breast cancer as well as the burden of breast cancer treatment put women at risk for psychosocial distress. Psychosocial distress impairs the immune system, impacting both natural killer cells and the production of cytokines. This is of particular importance to breast cancer patients because breast cancer can be responsive to natural killer cells and cytokines. These components of the immune system contribute to cancer control by protection from tumor initiation, primary tumor growth, and tumor metastasis. In the past decade, the number of women diagnosed with the form of breast cancer known as ductal carcinoma in situ (DCIS) has markedly increased. This increase in the number of DCIS patients is due to the widespread use of high- resolution screening mammography. DCIS is a significant clinical management problem and women diagnosed with DCIS face difficult treatment choices that must be weighed against not only the risk of cancer recurrence but also their personal values. Our preliminary data show that women with DCIS experience psychosocial distress that is characterized by elevated mood disturbance, anxiety, and perceived stress. Accompanying this psychosocial distress is immune dysregulation characterized by reduced natural killer cell function and reduced production of the cytokine interferon y. Such effects upon the immune system may have considerable impact upon the overall health and quality of life of breast cancer patients. However, surprisingly little is known about the molecular basis for the observed immune dysregulation. It is the overall purpose of this project to identify, at the molecular level, the basis for this immune dysregulation. This identification will be accomplished by determining whether peripheral blood mononuclear cell epigenetic modifications, subsequent to psychosocial-distress, mediate the immune-dysregulation. The specific aims of the project are to: 1) Identify peripheral blood mononuclear cell epigenetic patterns associated with psychosocial-distress mediated immune-dysregulation in women who are diagnosed with DCIS. 2) Evaluate whether epigenetic modifications are associated with specific dysregulated immune response genes in women with DCIS. This two-year developmental/pilot (R21) project will evaluate women with DCIS at 2 data collection time periods, one following breast cancer diagnosis and one 2 months after completion of cancer treatment. Results will be contrasted with a comparison group of matched women. The design of this project will provide for an identification of the peripheral blood mononuclear cell subsets, with demonstrable epigenetic pattern modification. Once identified, these subsets will be evaluated by chromatin immunoprecipitation and polymerase chain reaction to determine whether the observed epigenetic effects are associated with regulatory regions of specific immune response genes dysregulated in these women. No such analysis has been accomplished previously and this study will provide the first investigation of the epigenetic effects of psychosocial distress upon the immune system. Identification of an epigenetic basis for this immune-dysregulation will provide new insight into the effects of psychosocial-distress and will allow for future development of the means by which to manage this dysregulation. Such management will not only reduce the long-term adverse effects of immune-dysregulation but will also improve the overall health and quality of life of these patients.
Epigenetic Patterns Associated With The Immune Dysregulation That Accompanies Psychosocial Distress
Authors: Mathews H.L. , Konley T. , Kosik K.L. , Krukowski K. , Eddy J. , Albuquerque K. , Janusek L.W. .
Source: Brain, Behavior, And Immunity, 2011 Jul; 25(5), p. 830-9.
Related Citations
Glucocorticoid Dysregulation Of Natural Killer Cell Function Through Epigenetic Modification
Authors: Krukowski K. , Eddy J. , Kosik K.L. , Konley T. , Janusek L.W. , Mathews H.L. .
Source: Brain, Behavior, And Immunity, 2011 Feb; 25(2), p. 239-49.
Related Citations
Epigenetics And Psychoneuroimmunology: Mechanisms And Models
Authors: Mathews H.L. , Janusek L.W. .
Source: Brain, Behavior, And Immunity, 2011 Jan; 25(1), p. 25-39.
Related Citations
Psychologic Stress, Reduced Nk Cell Activity, And Cytokine Dysregulation In Women Experiencing Diagnostic Breast Biopsy
Authors: Witek-Janusek L. , Gabram S. , Mathews H.L. .
Source: Psychoneuroendocrinology, 2007 Jan; 32(1), p. 22-35.
Related Citations


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One good suit is worth a thousand resumes.


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The 1 Percent Candidate There's a secretive effort by mega-rich Wall Street titans to place a presidential candidate on the ballot in November. By Peter Hart Think big money and Wall Street have too much influence over national politics? Not to worry: A third-party presidential candidate bankrolled by hedge funds will fix all of that. …
Tag Archive: president
Jan 30 2012
The 1 Percent Candidate
Permanent link to this article: http://www.easttexasreview.com/the-1-percent-candidate/
Dec 13 2011
Influence Peddler for President
Gingrich, his lawyers, and his staff adamantly insist that it's rude and crude to call him a lobbyist. By Jim Hightower Mea culpa, I misspoke, my bad. I stand corrected. I have called Newt Gingrich a lobbyist. Apparently, he hates that tag, even though he has indeed gotten very wealthy by taking big bucks from …
Permanent link to this article: http://www.easttexasreview.com/influence-peddler-for-president/
Nov 16 2011
Newt for President?
By Jan Shedd Bag 1 Freddie Mac is one of the wildly corrupt government-subsidized lenders responsible for igniting our current economic woes. In 2004, President (GW) Bush correctly diagnosed its problem as a serious lack of oversight, and tried to pass some reforms. The Democrats in Congress blocked it (naturally). In 2006, John McCain warned …
Permanent link to this article: http://www.easttexasreview.com/newt-for-president/
Jan 20 2011
Former president fingers Williams for Senate
Ex-President George H.W. Bush has given his blessing to businessman and past Texas Secretary of State Roger Williams to fill the coming vacancy when Senator Kay Bailey Hutchinson retires in 2012. Bush was not sparing in his praise. "Roger Williams is a good man, a wonderful friend and an accomplished business leader who still understands …
Permanent link to this article: http://www.easttexasreview.com/former-president-fingers-williams-for-senate/


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Non-discrimination Statement
It is the policy of the Asian Society of International Law to comply with all Singapore nondiscrimination laws and the relevant Singapore government policies. This nondiscrimination policy applies to admissions, there employment, access to and treatment in the Society programs and activities. Complaints of invidious discrimination prohibited by Society policy are to be resolved within existing Society procedures.


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Check in from 14h / Check out prior to 10h
Adelaide Motel & Backpackers: Find photos, reviews, information, amenities and compare prices for 2 stars hotels in Adelaide, Australia.
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Paris-based ABC on new fund path with two more additions
Paris-based systematic event-driven firm ABC Arbitrage Asset Management has made a strong start with its second hedge fund, the ABCA Reversion Fund, since launching in May.
David Hoey
Its flagship offering, ABCA Opportunities, is also making good progress this year, and the firm has plans for additional launches early next year. These are expected to include a fund that will provide access to the firm's existing strategies.
ABCA Reversion is a statistical arbitrage fund employing a systematic market-neutral approach. The fund has made 7.25% in the four months since launch, including two particularly good showings


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Honda Gains After Raising Profit Forecast on Improving Sales in Asia, U.S.
Honda Motor Co., Japan's second- largest automaker, gained the most in seven weeks in Tokyo trading after raising its full-year profit forecast on improving sales in Asia.
Honda rose 4 percent to close at 2,818 yen, the most since June 14, after earlier climbing as much as 4.9 percent. The carmaker expects net income of 455 billion yen ($5.3 billion) in the year ending March, compared with an earlier estimate of 340 billion yen, the Tokyo-based company said in a statement after trading closed on July 30.
The maker of Accord sedans expects to sell 3.64 million vehicles this fiscal year, compared with an earlier estimate of 3.615 million, with gains in Asia outside Japan accounting for the increase. Honda's net income in the three months ended June 30 surged to 272.49 billion yen, more than double analyst estimates, from 7.56 billion yen a year earlier.
Honda "revised up first-half operating profit well beyond Deutsche Bank's estimate," Kurt Sanger, an auto analyst at Deutsche Bank AG in Tokyo, wrote in a report today. First- quarter operating profit "far exceeded our expectations," said Sanger, who rates the stock "buy."
Honda, the world's biggest motorcycle maker, also raised its two-wheeler sales forecast to 10.82 million vehicles from 10.38 million.
Stronger Yen
The company's operating profit may be eroded by 80 billion yen as the Japanese currency gains more than previously forecast, Honda said. The automaker based its full-year profit estimate on exchange rates of 87 yen to the U.S. dollar and 112 yen to the euro. In April, Honda expected the currency to average 90 against the dollar and 120 against the euro.
A rising yen against the two currencies reduces the repatriated value of earnings from sales in the U.S. and Europe.
A revamped Odyssey minivan and better inventory management of CR-V, Pilot and Fit models will help sales in the U.S., Honda Executive Vice President Koichi Kondo said on July 30.
Honda's deliveries in North America, its most profitable market, rose 15 percent in the first quarter as the U.S. economy recovered, while Japan sales jumped 13 percent on government subsidies for car buyers. Sales in other Asian countries surged 38 percent.
Higher factory utilization cut fixed costs by 40 billion yen in the three-month period, Kondo said.
The carmaker's first-quarter output in China rose 4.3 percent to 149,109 units, even as its sales in the country fell 2.4 percent in June after strikes at suppliers forced the carmaker to halt production.
To contact the reporter on this story: Makiko Kitamura in Tokyo at firstname.lastname@example.com


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Study Abroad 101 Info Session
Learn about the application process to study abroad during a semester and/or short-term.
Learn about the application process to study abroad during a semester and/or short-term.
Interested in studying abroad? Visit the information table in Maucker Union for more information regarding semester, short- term and Capstone programs.
UNI Gallery of Art Concert Series, in association with the exhibition "Remix: Art and Sound Unbound" featuring avant-garde music and art.
Want a change of scenery? Get UNI credits at a partner university abroad for a semester. Listen to UNI students who have studied abroad for a semester. Classes are taught in English or the host country's language. Many major options are available.
The Study Abroad Center will present information about on- and off-campus scholarship opportunities.
The Study Abroad Center will provide information about a short-term program in New Zealand during winter break 2014. Travel with UNI students and course leader.
It seems as though people either love rubrics or hate them. Some appreciate the time that rubrics can save; others find them too restrictive and generic. This session, led by Catherine Miller, mathematics, and Susan Hill, CETL, will explore the advantages and disadvantages of using rubrics for grading, which rubric is best for a task or project, examine a variety of different kinds of rubrics and discuss when using rubrics can be most beneficial to you and your students.
Regular meeting of the UNI Faculty Senate; open to all.
The Van Cilburn gold medal is the highest competitive honor a pianist can achieve. The Gold Medalist of the 2013 competition will take the Gallagher-Bluedorn stage following his or her coveted victory.
When Weston family patriarch vanishes one hot summer night, his acid-tongued, pill-popping wife summons her grown daughters and their families to their Oklahoma homestead. Dinner is served, lies are told, and long-held family secrets are unflinchingly revealed. Tracy Letts' comic tragedy exposes the emotional destruction that rips through generations if nothing stops its path. One of the most critically acclaimed plays of this century, August earned the 2008 Pulitzer Prize for Drama, Tony Award for Best Play, and Drama Desk Award for Best New Play. Directed by alumna Angie Toomsen and featuring UNI faculty Richard Glockner and Cynthia Goatley.


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- Enjoy £1.00 credit to spend on movies or TV on Amazon Video when you purchase a DVD or Blu-ray offered by Amazon.co.uk. A maximum of 1 credit per customer applies. UK customers only. Offer ends at 23:59 GMT on Wednesday, December 20, 2017 Here's how (terms and conditions apply)
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Doctor Who: The Complete Specials [Blu-ray] [Region Free]
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This 5 disc set includes the following -
The Next Doctor
The Next Doctor Feature (SD to HD up conversion)
DTS HD 5.1 Audio on feature only
The Next Doctor Confidential (SD to HD up conversion)
Doctor Who at the Proms (SD)
Dolby Digital stereo audio on extras
Planet of the Dead
Planet of the Dead feature (HD)
DTS HD 5.1 Audio on feature only
Planet of the Dead confidential (HD)
Dolby Digital stereo audio on extras
The Waters of Mars (HD)
DTS HD 5.1 Audio on feature only
Waters of Mars confidential (HD)
Dolby Digital stereo audio on extras
The End of Time - Part 1 (HD)
DTS HD 5.1 Audio on feature and confidential
The End of Time - Part 1 - Confidential (HD)
David Tennant video diary - The Last Days (SD)
BBC idents (SD) Audio commentary on feature Dolby Digital stereo audio on extras (except Confidential)
The End of Time - Part 2 (HD)
DTS HD 5.1 Audio on feature and confidential
The End of Time - Part 2 - Confidential (HD)
Russell T.Davies intro to deleted scenes (HD)
Doctor Who at Comic-Con 2009 (HD)
Audio commentary on feature
Dolby Digital stereo audio on extras (except Confidential)
The Next Doctor: It's Christmas Eve in 1851 in The Next Doctor and Cybermen stalk the snow of Victorian London. When the Doctor arrives and starts to investigate a spate of mysterious deaths, he's surprised to meet another Doctor (David Morrissey), and soon the two must combine forces to defeat the ruthless Miss Hartigan (Dervla Kirwan). But are two Doctors enough to stop the rise of the CyberKing?
Planet of the Dead: Starring Michelle Ryan and Lee Evans, Planet Of The Dead was the first of this year's specials. When a London bus takes a detour to an alien world, the Doctor must join forces with the extraordinary Lady Christina. But the mysterious planet holds terrifying secrets, hidden in the sand. And time is running out, as the deadly Swarm gets closer...
The Waters of Mars: The Waters of Mars welcomes Lindsay Duncan as the Doctor's cleverest and most strong-minded companion. The Waters of Mars is a dark, scary thriller that sees the Doctor land on the planet Mars, at a base in peril. A creeping infection beneath the Martian surface threatens not only the human race, but also the Doctor's most fundamental beliefs. Together with Adelaide Brooke - the base's commander - the Doctor must stop a seemingly unstoppable menace before it can reach Earth, and wipe out mankind.
The End of Time: Part One: Join the Tenth Doctor for his final journey in The End of Time Parts One and Two, when his psychotic nemesis the Master has been reborn, on Christmas Eve. With both determined to cheat death, the battle ranges from the wastelands of London to the mysterious Immortality Gate, while the alien Ood warn of an even greater danger approaching, as a terrible shadow falls across the entire Universe.
The End of Time: Part Two: The Doctor faces the end of his life as the Master's plans hurtle out of control. With the sound of drums growing louder, and an ancient trap closing around the Earth, the Doctor and Wilf must fight alone. But sacrifices must be made, and the deadly prophecy warns: "He will knock four times."
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First up is the 2008 Christmas special THE NEXT DOCTOR in which the whole idea that this Doctor might not be forever is addressed. David Morrissey guest stars when the Doctor meets a figure not unlike himself having adventures during a Victorian Christmastime and a comic tragedy unfolds that mixes Dickensian imagery with Cyberpunk as the Cybermen return with the help of Dervla Kirwan in a plot involving the kidnapping of street urchins to help create their Cyberking where only the Doctor(s) and a very different type of TARDIS can save the day.
By Easter, the Doctor has taken to riding buses around London, but even a simple bus journey can't be uneventful as before you know it he's been transported to THE PLANET OF THE DEAD with only Michelle Ryan's cat-burglar and a busload of passengers (as well as Lee Evans and UNIT) to help get him home. The stakes are high as a race of planet-eating flying manta rays are getting ever closer...
The darkest, scariest moment happens fifty years in the future when THE WATERS OF MARS are threatening to overrun Lindsay Duncan and her crew on Bowie Base One. The fact that they're all already doomed adds a dark edge to the story, but when the Doctor himself decides that he won't put up with that any more things take an even darker turn.
Back to Earth at Christmas again (via the planet of the Ood) for this Doctor's final battle.Read more ›
In my opinion, the quality of the stories really took off when Tennant came on board and had peaked at Series 4 (which remains my favourite series of Doctor Who bar none). And then after an amazing five year run, after so many painful departures...the man himself David Tennant declared that he was finally leaving.
It shocked me to the core, along with everyone else. For me (and millions more), he was MY Doctor. He made me a fan, and the fact that Russell T Davies was also calling it a day was heartbreaking.
So this boxset, containing the final five specials of the Davies era, marks the end of a truly wonderful era. Taking place after the monumentally superb Series 4, the premise here is the Tenth Doctor (after vanquishing greatest enemies Davros and the Daleks and saying goodbye to his best friend Donna Noble) is once again on his own. After losing so much, the Doctor decides its best to remain on his own and not to endanger anyone else and risk his heart being broken again.
These five specials (spanning from Christmas 2008 to New Year's Day 2010) feature David Tennant and a delightful all-star guest cast. Here he has a different companion for the duration of each adventure, resulting in some terrific, classic episodes, all running for an hour except the BIG FINALE, which runs for a stonking seventy-five minutes.Read more ›
The Next Doctor
Doctor Who at the proms
The next Doctor confidential
New special moving menus
Planet of the Dead
Planet of the Dead Confidential
New special moving menus
The Waters of Mars
Waters of Mars confidential
The End of Time: Part One
Xmas confidential
David Tennant video diary - the final days
BBC idents
Audio commentary on feature
The End of Time: Part Two
New Year confidential
Russell T Davies intro to deleted scenes & deleted scenes
Doctor Who at comic-con 2009
Audio commentary on feature
Where does it say that EVERY story must be tense, exciting, original and scary? Just check out the original series for some wonderful clunkers! These specials should be taken for what they are: Popular family-oriented science fiction adventure. It's designed to appeal to the masses - it wouldn't be Doctor Who if it didn't - so why read more into it than that? OK some of the plots are wafer thin and some of the designs are ludicrous - what were they thinking of when they brought us the Cybershades? - but the whole is greater than the parts and the series marches on.
How would I rate these specials if pressed in a convention bar? Well, "The Next Doctor" was a bit of a disappointment as I just don't like huge robots, especially Cyberman ones! "Planet of the Dead" was better, despite the flying bus, "Waters of Mars" was actually quite good, but what happened to the Doctor towards the end? He's never gone quite so far out before, possibly the nearest the character has ever come to this was in the Tom Baker scene from "Genesis of the Daleks", where the Doctor debates the moral rights of the Daleks to exist at all. The final two-parter veered between daft and magnificent. If a casual viewer had tuned in for these, they would be left dazzled and mystified in turn. The Master Race? Too silly! The ACTUAL knocking four times - too brilliant for words! After saving the human race, the Doctor gives his life to save one old man? Fantastic! But would he have done this if he did not know the prophecy of his death? Probably!Read more ›
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As a massive Doctor Who fan, I love having all things Who, The specials with David Tennant are difficult to review as its *spoilers* the end of his era as the doctor and the end of... Read morePublished 3 months ago by Aimie
i have enjory the dr who : the complete specials on the Blu-ray and i like it very much.Published 7 months ago by Amazon Customer
Product not as advertised. The box is actually the new version with a different logo. Just in case like me you prefer to complete the old collection.Published 7 months ago by .I.D.H.
Brilliant purchase, have watched numerous times - it's the gift that just keeps on giving!!
Thank you very much. Highly recommend this item and the vendor.
I've always liked doctor who awesome one of the best tv shows ever madePublished 9 months ago by Xfactor
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Darnell Smith
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Darnell Smith was booked in Cook County, IL on 11/14/2011.
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The following Official Record of Darnell Smith is being redistributed by Mugshots.com and is protected by constitutional, publishing, and other legal rights. This Official Record was collected from a Law Enforcement agency on 11/15/2011.
Mugshots.com ID: 4587367
Inmate Number: 2011-1114137
Name: SMITH, DARNELL
Birth date: 7/11/1979
Race: BK
Gender: Male
Height: 6′ 0″ (1.83 m)
Weight: 245 lb (111 kg)
Booking Date: 11/14/2011
Location: 02-
Visiting Info: - Call 773-869-7100 for Visit Information
Bond Set Amount: Bond in Process
Charges: N/A
Court Info: N/A
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Mississippi. The Spirit of America's Veterans in ponce rest in the ramp Thanks to Victor and brother Roberto
109th Airlift Wing member ( Pride of Rotterdam) New York ANG Redy to take off to SJU(Skier 89).
145 AW SQ Take off to direct to SJU from PSE very heavy take off. to this member of North Carolina ANG.
Niagara ANG 914 AW 107AW New York Air Guard in Ponce the firs time i can see this C-130 in this airport.
Nashville Tennesse 118 AW SQ Backtaxi to the ramp over the runway.
Maryland ANG 135 AG SQ arriving in Mercedita.
Pawa arriving from MDSD Santo Domingo in the first one of two flights to Ponce.
Usa Jet arriving from Punta Cana in 7000 feet runway touch down in 4000 feet of runway 30 of Ponce the full brake in this shot note the left gear smoking power full reverse trusth.
The first fligth of USA JET in Ponce Mercedita operates for Holiday Air charter fligth to Punta Cana. SonyAlpha100 Sony 70-300mm G SSM.
Cape Air and IFAW paint the plane to bring whale protection to the public eye. IFAW works around the globe to protect animals and their habitats and to create a better world for animals and people... (more)
Missisippi ANG 172AW SQ make a short take off in Ponce Mercedita. i hope see soon the C-5 Galaxy once again in this airport.
Jetblue Taking off from PSE to SJU JBU740.


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text:
Cellular function depends on highly specific interactions between biomolecules (proteins, RNA, DNA, and carbohydrates). Alpha-helices, ubiquitous elements of protein structures, play fundamental roles in many of these interactions. Alpha-helix mimetics that can predictably disrupt these interactions would be invaluable as tools in molecular biology, and as leads in drug development. We have succeeded in creating a general approach for the synthesis of short stable alpha helices that can target chosen biomolecular interactions. Our strategy involves replacement of one of the main chain hydrogen bonds in the target alpha-helix with a covalent bond. The internal placement of the crosslink makes it possible to take advantage of the full helix functionality for molecular recognition. We have demonstrated that this new method results in unusually stable artificial alpha-helices. In this application, we explore the utility of these artificial helices for targeting complex signaling networks. With regards to specific aims, (1) We will create a conformationally and metabolically robust family of HBS helices. (2) We will construct a database of experimentally determined structures of helix-mediated protein-protein interactions and determine hot-spot residues in the helical protein interfaces. (3) We will develop structure-based ligands to help decode the GTPase signaling networks, and evaluate a new paradigm for discovery of specific inhibitors of protein kinase activity. Combined these three aims will offer rationally designed inhibitors of protein- protein interactions, and validate our design principles that are rooted in the fundamental theories of biophysics and physical organic chemistry.
Selective modulation of protein-protein interactions is a grand challenge for chemists and biologists. The ability to systematically modulate protein-protein interactions would greatly facilitate the discovery of candidate therapeutic agents for a broad range of diseases. The proposed research offers a synthetic method for developing artificial alpha-helical ligands for targeting chosen protein interfaces.
|Watkins, Andrew M; Arora, Paramjit S (2015) Structure-based inhibition of protein-protein interactions. Eur J Med Chem 94:480-8
|Miller, Stephen E; Thomson, Paul F; Arora, Paramjit S (2014) Synthesis of hydrogen-bond surrogate ?-helices as inhibitors of protein-protein interactions. Curr Protoc Chem Biol 6:101-16
|Watkins, Andrew M; Arora, Paramjit S (2014) Anatomy of ?-strands at protein-protein interfaces. ACS Chem Biol 9:1747-54
|Miller, Stephen E; Watkins, Andrew M; Kallenbach, Neville R et al. (2014) Effects of side chains in helix nucleation differ from helix propagation. Proc Natl Acad Sci U S A 111:6636-41
|Xie, X; Piao, L; Bullock, B N et al. (2014) Targeting HPV16 E6-p300 interaction reactivates p53 and inhibits the tumorigenicity of HPV-positive head and neck squamous cell carcinoma. Oncogene 33:1037-46
|Raj, Monika; Bullock, Brooke N; Arora, Paramjit S (2013) Plucking the high hanging fruit: a systematic approach for targeting protein-protein interactions. Bioorg Med Chem 21:4051-7
|Kushal, Swati; Lao, Brooke Bullock; Henchey, Laura K et al. (2013) Protein domain mimetics as in vivo modulators of hypoxia-inducible factor signaling. Proc Natl Acad Sci U S A 110:15602-7
|Bergey, Christina M; Watkins, Andrew M; Arora, Paramjit S (2013) HippDB: a database of readily targeted helical protein-protein interactions. Bioinformatics 29:2806-7
|Drew, Kevin; Renfrew, P Douglas; Craven, Timothy W et al. (2013) Adding diverse noncanonical backbones to rosetta: enabling peptidomimetic design. PLoS One 8:e67051
|Henchey, Laura K; Kushal, Swati; Dubey, Ramin et al. (2012) Correction to Inhibition of Hypoxia Inducible Factor 1-Transcription Coactivator Interaction by a Hydrogen Bond Surrogate ýý-Helix. J Am Chem Soc 134:8000
Showing the most recent 10 out of 32 publications


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Matt Macduff: The Ten Commandments
Filmed/Edited by Justin Browne. Rider: Matt Macduff. Music: Pyramid Theorem. http://www.myspace.com/pyramidtheorem1 Locations: Aurora,New market, Oak Ridges. http://www.dobermannbikes.blogspot.com/ http://allaboutbikes.tk/
matt is freakin crazy!!!!!!!!!! VOD! WOOOOOOOO[Reply]
damn this guy is goood! ontario represent[Reply]
dope vidoe and he has the same shoes as me[Reply]
matt rules school bus tuck nos rule dailed barspins rule this video should get vod[Reply]
Lol, I love how he randomly goes bush waking at 108, but sweet vid, definitly vod, and hey, he is wearing his helmet[Reply]
sick vid, vod![Reply]
This vid is Sick VOD!!!![Reply]
well it seems to me he's got the barspins dialed! sick video, vod for sure[Reply]
very nice, should be vod![Reply]
green wallmart?[Reply]
i love the smirk at the start[Reply]
back2bs (Jun 5, 2009 at 18:57) (Below Threshold) show comment
he has my shoes! lmao. AWSOME VID TOO[Reply]
NO. you have his shoes. COPY CAT!![Reply]
the song makes me want to cut off my eats, but good riding[Reply]
he would be way better if his pants werent so tight[Reply]
LIES! he rocks the pants! i love this kid, soooo fucking street, i love those tucks down stairs and those dumpster jumps![Reply]
Did i just see a flat, tuck no hander?[Reply]
Please stop the barspins.[Reply]
way too many barspins[Reply]
haha sick skills. First street video with metal music(?) p.s. no helmet no vod is broken!:P[Reply]
yaa matt!![Reply]
music boring as fuck, riding is the only thing that kept we watching it, and i say mad props to the guy for such sick riding. just edit better and get a better song.[Reply]
Was this filmed in Langley BC?[Reply]
Locations: Aurora,New market, Oak Ridges[Reply]
If you could read.
If you could read.
11th commandment: thou must sling the sickest of barspins off everything[Reply]
shit vod to boring[Reply]
sorry, but wow that was boring, and were you trying to choose the worst possible music on a pinkbike video ever?[Reply]
someones likes bar spins[Reply]
good tricks but you ride like a machine, get some steeze in your riding. But good tricks[Reply]
Matt Mcduff only has one commandment- thou shall barspin everything[Reply]
this guy has tricks but no style or flow with them, always to quick. not my kind of vod[Reply]
he is the first hesh mountain biker![Reply]
i generally ride brakes on my bikes....but with trials and dh you dont have a choice.[Reply]
great vid, but that guy needs to get a hair cut![Reply]
i got a coupon for supercuts if he wants it...[Reply]
if that guy rode a bmx hed get 10x better[Reply]
No flow what so ever. I didn't enjoy this vod at all. If he stopped barspinning everything, it'd be a lot better.[Reply]
He does quite a lot of barspins!![Reply]
i completely agree wil. all that there was were bar spins and 3's. not that thats not hard, but it was repetitive and forced.[Reply]
VASCOgva (Jun 17, 2009 at 12:12) (Below Threshold) show comment
song? its sick!!!!!!!!!!![Reply]
It would be a sick video if he didnt repeat every trick atleast 50 times.[Reply]
Matt GOt VOD!!! Guess what this video beats your gay DH racing anyday and this guy right here. learned to bike in ontario. I'd to see you guys do any of that.[Reply]
dh isnt gay man ive onl tryed it once but its much more fun then park, street snd dirt.[Reply]
how can you say DH is gay when it takes so much more balls to go fast?![Reply]
DH sucks to watch matts way cooler then any of those stupid athertons or any other DH videos on this stupid site. I ride with this guy. him getting vod Is really cool. plus he's sponsered by Dobermann so all you stupid kids should show some respect and as for the music its like a local rock group trying to make it just like Matt and it fits the video.[Reply]
keenan, we DHers appreciate street/jumps/trials/park etc. so whay do you have to be so arrogant towards us? I ride DH mostly, i race xc and i ride street/trials. all have their hooks, and none are 'gay'.[Reply]
this is a pretty lame argument man. riding style is all super opinionated. not one style is better than another, they are just different and attract different people. i personally like dh better, but have mad respect for dj and street as i ride that too and realize how hard it is too do the stuff guys like matt can throw down[Reply]
ok, i had to put my own music on to enjoy it, and yes there were too many barspins, and yes the editing and filming was bad, but this guy still has talent - he's a really good rider, the only reason people cant see that is because they are too acustomed to watching their well groomed pro level riding imo.[Reply]
I never said I hate DH. I used ride DH and I owned a fully. all I'm saying is I'm sick of people always saying DH videos are the best videos which they so aren't. Matts a really good biker. all these people sign up to watch that crap and when they don't see it half of them have nothing nice to say about any of it.[Reply]
that definetly wins the "worst VOD ever trophy" way too many barspins!!!!!!!!!!!!!!!!!!!!!!!! cant wait for the dh VOD tommarow!!!! and the music was really shitty f*ck that song and f*ck the vid...try again later dumb ass matt!!!![Reply]
sick vid!! hes sponsered by dobbermann[Reply]
Pretty good! but where's the helmet?[Reply]
AMAZING!! but too many barspins and where do u live in canada it looks like around where i live[Reply]
yes yes yes, soooo bmx, yet soo mtb, fuckin loved it[Reply]
too many barspins but the vid was still pretty dope. id say get a bmx cuz shit would be alot easier but whatever floats ur boat i guess. either way the vid was pretty ballin[Reply]
Everywhere I go on this site, everyone is bitin everyone else's style. Not cool.[Reply]
welcome to pinkbike. if you want real help and nice people go to mtbr.
welcome to pinkbike. if you want real help and nice people go to mtbr.
ROFL 44 negs mo fukers !!!!![Reply]
i dont think he did enough barspins[Reply]
everyone calm the f*ck down..[Reply]
we got the fact he does alotta barspins,
and to anyone that said go bmx im pretty sure ive seen him ride one before but he either sold it or broke it i cant remember.
and to jojojof: read the description man
we got the fact he does alotta barspins,
and to anyone that said go bmx im pretty sure ive seen him ride one before but he either sold it or broke it i cant remember.
and to jojojof: read the description man
i love cow hide skinnies[Reply]
look at the vid again. his forks dont move at all???[Reply]
wuts up with all the with all mountain bikers ridin street. dont get me wrong boss ass riding but y dont u just ride a bmx if ur gonna ride street. much lighter[Reply]
@colinecoop, we find it alot more comfortable to be on a big boy bike. not so hucnhed over. It limits the tricks and stuff sure, but I've found it to be a lot more comfortable and a lot more forgiving.[Reply]
my friends mtb is set up to 23lbs...thats lighter then most bmx[Reply]
ya thats pretty fuckin light. alrite well i guess wutever u mountain bikers feel comfortable with go for it. its just not my style[Reply]
i personally dont like street on a mtb nor would i ride a 23lb mtb thats just sketchy light i was just making a point i would much rather ride bmx for street[Reply]
haha well then what was the point of saying anything then!![Reply]
Surely it should be called "Matt Macduff: Can barspin and 360"[Reply]
sick vid but to many b-spins 4 me but mad props on the tucks especially off the curb[Reply]
ya pretty much ever second shot was a barspin...[Reply]
THERE'S NO SUCH THING AS TOO MANY BARSPINS WHEN TALKING ABOUT MATT MACDUFF[Reply]
19 bar spins!! but nice riding[Reply]
i agree, waaaay too many barspins. i think there were only really 4 or 5 tricks in total? didnt relly enjoy the video.[Reply]
yeah only like 6 tricks on different terrain...i was waiting thru the whole vid for it to get better but then i just focused on the # of f*cking barspins...god that was shitty!!!![Reply]
haha your a little fucking late on the comments d bag[Reply]
bike buster will do anything in his power to try and run the comments i love it hahahahaha ![Reply]
bikebuster (Jul 3, 2009 at 1:50) (Below Threshold) show comment
u should change your name from justbmx to i-justbmx-and-suck-at-it!!!!haha[Reply]
and you should go back to school and get a job instead of chirpin on pinkbike videos change your name from bikebuster to umm i-like-ballsacks-in-mouth[Reply]
yeah and change your name to "Euro-peice-of-shit-biker" it would sound like "your a piece of shit biker"... just in case you dumb f*cks pernounce sounds differently than us americans[Reply]
let me know when you get VOD bikebuster hahahahahahahah !!!
let me know when you get VOD bikebuster hahahahahahahah !!!
I laughed sooo hard when i read the above comments[Reply]
i also laughed even harder when I click on his account of bikebuster saw this...[Reply]
This account has been suspended.
(4947 hours remaining)
This account has been suspended.
(4947 hours remaining)
haha click on my account now!!!! hahaha and im sorry to all the people i pissed off or offended in anyway[Reply]
your still a douche bag.[Reply]
haha dont care what you think..can still ride a bike better[Reply]
for all the comments on this guys pants and hair...[Reply]
what is this???
This is pinkBIKE
- not pinkfashion.
And even if it was a fashion site, he would probably still be vod. He's style is cool and different then some maybe, but theres nothing wrong with that.
Stay on the topic Boys N Girls.
what is this???
This is pinkBIKE
- not pinkfashion.
And even if it was a fashion site, he would probably still be vod. He's style is cool and different then some maybe, but theres nothing wrong with that.
Stay on the topic Boys N Girls.
me2menow (Jun 17, 2009 at 12:04) (Below Threshold) show comment
nice try but theres no such site as pinkfashion![Reply]
aint no fucking style in this. just a guy copying bmx best he can and failing miserably at it.[Reply]
180s, 360s, barspins... a couple tuck no handers and a tailwhip at the end... not a lot goin on there, imo. it was a whole video consisting of 5 tricks. granted, he's a decent rider, better than I am right not. just not feelin' the vod thing for this. Props to him though, he's dialed....[Reply]
yeah...cool that you can do those tricks but boring vid[Reply]
Wait? I fell asleep. What happened at the end!?[Reply]
Jasongsd.. HAHA :LOL: Your comment made me laugh. Props![Reply]
too many bar spins for me. i thought the video was quite repetitive. good riding though.[Reply]
fuck you[Reply]
no bud, fuck YOU!!!!![Reply]
yankie bitch[Reply]
your calling bikebuster a yankie bitch?????? what the f*ck you ass hole bikebuster ride so well and smoothly, check out his profile and then say hes a yankie bitch, EH???? f*cking canadian!!!![Reply]
wow he rides downhill... that makes him even more gay .... by the wayy.. your gayy too.. get some real beer in your country then talk to me[Reply]
Shut up you fucking Shitheads neither Matt or Justin or any of us Ontario People that will kick the shit out of you at biking need to hear your comments on this video.[Reply]
konashed-rider1...wow i thought u canadians were cool but u basically changed that...f*ck u... and dont dis on DH just because you cant do it!!!!!! and keenanbikes...im pretty sure that u suck at biking...your profile is a JOKE!!!! and matt and justin both suck ass at riding...that was the worst vod ive ever seen...f*ck u...how much did you pay pinkbike to have them put that vid and make it vod on there???????[Reply]
Thanks for all the comments, views, and favs everybody. hi haters, i see you.[Reply]
and another thing, saying keenan, matt or i suck at riding wont change anything. These guys are putting in work everyday and what are you doing? Take a look at your own profile there buddy, you post pictures of broken konas and how hard you push them to the limit. I really wanted to avoid commenting like this but i couldn't hold back any more. Seriously go out and ride your bike instead of bashing every video and picture you see on the pinkbike. Maybe even rethink a new hobby or sport because im not sure if DH is doing it for you.[Reply]
Where going to keep on doing what we do regardless of what you say so keep hating, i love hate.
Where going to keep on doing what we do regardless of what you say so keep hating, i love hate.
wow, i started this?[Reply]
i do push my bikes to the limit...is there some sort of problem here??? have you EVER seen a broken bmx bike???? no because you and bmx riders in general are f*cking pussy!!! you ride around it a little park, do a bunch of hella gay spins and BARSPINS...i mean wtf is that..hella gay...so dont go around bashing me or other DH guys because you could never do the things we do!!!![Reply]
Hey!! bike buster why don't you: bust a nut on your daddies face and maybe he will buy you a new shitty kona to ride on. because we don't care what you do[Reply]
oh how thoughtful!!!! umm actually i buy my own bikes and now i have a norco team DH... there is no way in hell u can put shit on norco!!!! just because your a poor ass SOB doesnt mean you have to be an ass hole to other people....Ohhhh i see now...u got into bmx because you can get a bike for 350 fucking dollars!!!! you gotta pay to play..and damn, i sure am playing!!!![Reply]
I'm being an asshole to you cause your ripping on my friend for Getting VOD yesterday and he deserved it and you suck at biking[Reply]
nahh let this guy say what he wants who cares.[Reply]
well your friend does suck at biking...that vid was not VOD worthy at all!!!!!!!!!!!!!!!!![Reply]
hey now. i ride bmx and DH. and i don't really get what the big deal is, some people like to go big. and others like to ride around and do spins... just do what you love. stop arguing about which is better and go ride your bike![Reply]
wow mess you dont think this is VOD worthy, you really need some sense kicked into your rattling, peanut head mate..[Reply]
I havent ever seen street done so well on an MTB! I mean a tuck no hander off a curb? what the fluff I didnt even think that was possible, mega props to this guy, he has style and balls *eek*[Reply]
really sick style! abit to many barspins in my opinion, but still pretty sick with such a wide bar[Reply]
i thought that he was good, but wayyyy 2 many barspins and no handers, i mean ffs, learn some new tricks. was some sick ridein tho.[Reply]
this guy has the worst style ive ever seen. not POD material.. he almost missed the handle bars like 10 times. the whole vid consist of like 3 tricks. and i just think that there are way better vids. NEG PROP ME IF YOU WANT. idc[Reply]
im open to suggestions on what you would like to see in the future. instead of just saying more variety tell me exactly what you would like to see.[Reply]
mabey something new that we havent seen before....[Reply]
something more extreme mabey?
combine the two and it wud be sorted!
something more extreme mabey?
combine the two and it wud be sorted!
yeah or turn the vid into a 30 second vid by taking out all the mother f*cking barspins!!!!!!! god havnt you f*cking relized that all the comments say the the barspins were hella anoying?!?!?!?![Reply]
I just fvcking hate it to see dumba$$ kids that are too dumb to realize they need a helmet for doing trials.[Reply]
Regardless, I don't understand why this is VOD. It's a totally lame video, the angels are horrible, and that's the worst music for an MTB (or trails or street or bmx) clip I've ever heard.
Regardless, I don't understand why this is VOD. It's a totally lame video, the angels are horrible, and that's the worst music for an MTB (or trails or street or bmx) clip I've ever heard.
sooo.. can he do a barspin?[Reply]
call me what you will, but could he fit into any tighter of pants?
and "10 commandments" video? With something sounding like Pantera in the background? hmm.
negative prop as you please.
call me what you will, but could he fit into any tighter of pants?
and "10 commandments" video? With something sounding like Pantera in the background? hmm.
negative prop as you please.
No helmet = no brainer. This shouldn't be promoted, no matter how many barspins.[Reply]
stop crying about it if he dont want to wear a helmet then he dont have to. like how f*cking often do you fall on your head? i mean your more likey to fall on your hands and break your wrists or clean snap your leg in half than hit your head. c*nt[Reply]
shut it u fag ur the one crying about people crying hahaha[Reply]
Why such an offensive little twit?…broken arms and legs heal, but a brain injury screws you for life...if you live. You're very likely to hit your head biking. If you haven't yet, you will.[Reply]
its ok, hes a bmxer it doesnt matter if they fall on there head there dumbarses anyway, they only ever move at 5-8mph on a skate park so they wouldnt no what it feels like to take a facefull of dirt after a hard landing[Reply]
oh shock i didnt hear any of you go "yeah i hit my head" dick heads...[Reply]
oh yeah im a dumbarse? comming from you know do tricks that bmx's have been doing for years and try it on a mtb and when you dont do it you blame it on "oh yeah im on a mtb thats why i didnt land it". also how f*cking fast do you go round a park? or so you only ride the jump box coz you cant hop?
not to mention a broken leg can effect you for life, like even a broken foot can so dont give me that shit.
oh yeah im a dumbarse? comming from you know do tricks that bmx's have been doing for years and try it on a mtb and when you dont do it you blame it on "oh yeah im on a mtb thats why i didnt land it". also how f*cking fast do you go round a park? or so you only ride the jump box coz you cant hop?
not to mention a broken leg can effect you for life, like even a broken foot can so dont give me that shit.
o dear looks like sum1 stayed up to late last night and drunk to much coke and has got a little upset. id suggest going to bed early tonite.[Reply]
how can this be VOD great riding but no helmet, arent we supposed to be promoting safe riding??? prob get negative props for this comment but I dont care, wear your helmet[Reply]
whaas gonna catch his brain parts if his head go splat?? helmets work good for me, but maybe can barspin his brain back together sick vid should hav had a helmet wit hella stickers on there to rep anything u wanted[Reply]
he is good and all but not vod for me, there just wasnt really anything special about this vid it was the same stuff over and over again[Reply]
yu try doin half the stuff hes doing, and plus he is sponsered by dobbermann so obviously he MUST be doing something right.[Reply]
i know, i didnt say i was better it was just my opinion.[Reply]
all he did was barspins, tuck no's 180's or 3's! hes a good rider and way better than me but a vid that long deserves alot more tricks! not just a combination of the four above![Reply]
totally agreed this guy sucks!!!!!!!!!!!!!!!!!![Reply]
180 over trash bin was fucked[Reply]
yah dude this should get alot of props because he dropped a school bus to flat and no handed it!!![Reply]
sick riding, but only chicks should wear pants that tight[Reply]
You gave him VOD for his trousers or what? ;D[Reply]
sorry but i don't like it, maybe reason is the music... who knows
sorry but i don't like it, maybe reason is the music... who knows
agree that alot of tricks were repeated. no helment half the time. but the tricks he did pull off were pretty clean. props on the good riding though.[Reply]
not sure if he can barspin like?[Reply]
justbmx has got the right idea,everybody is bitching about the amount of barspins but barspinning is pretty much the main street trick,ive ridden with matt and hes an incredible rider,as to his style,clearly none of you who are taking shots at him have ever been to ontario,thats the style down here,it makes you more aerodynamic Props matt! great video[Reply]
Ok I definitely think the riding is good... But the kid looks like a FAG!!! LOOK AT HIS PANTS!!!! and the headband!!![Reply]
haha, its to hold his hippy hair - to lazy to cut it i guess! lol[Reply]
wow you guys are all fucking faggets, have some fucking respect... the kid is representing ontario hard and you guys are just chirpin the shit out of him. shut the fuck up and show some respect[Reply]
LOVED the floaty 1's over the dumpster. and btw everyone saying too many barspins, he gets the idea! i was scrolling down these comments and its like[Reply]
too many barspins
too many barspins
too many barspins
be more like the biker and chilllll
too many barspins
too many barspins
too many barspins
be more like the biker and chilllll
(seen a broken bmx bike???? no because you and bmx riders in general are f*cking pussy!!!) This is one of the stupidest things that I have read on here. A BMX is made of chromoly steel a piece of shit Kona is made of shit quality aluminum, chromoly bends aluminum snaps you stupid person.[Reply]
there is more broken bmx parts in the world then mtb parts...[Reply]
jordo5.... do you have any f*cking proof that the statement you said is true? and wow, did someone just say bmx riders are pussy? go look at videos of mark webb, maybe that'll straighten up your mind a lil.[Reply]
colt fake SNM[Reply]
that was an amazing vod. what the hell do you know^^^. that was like a new level of street[Reply]
11th Commandment: Thou must not wear your sister's pants![Reply]
not denying he is good but he only done 5 tricks! nice style n all but soo boring, i think i predicted every trick before he done it! faggot trousers too!![Reply]
that's odd, i counted more than 5.[Reply]
yeah there was lots, even a valder[Reply]
just plain disgusting. way to set the bar for ontario street riders[Reply]
How is it disgusting???[Reply]
disgustingly awesome[Reply]
f*cking hippie, good job man... ontario(y) but im not gay so change those pants[Reply]
i dont really like this video, all 180's with bar spins. and a rider with a lack of smooth riding, it sounded painful whenever he landed.[Reply]
i hate barspins now lol[Reply]
jeharv (Jun 17, 2009 at 17:55) (Below Threshold) show comment
why do you hate bar spins[Reply]
because there was to many of them duh...[Reply]
i ahte barspins 2 now[Reply]
I agree. There are 19 fucking barspins in this video. Yes, I counted.[Reply]
So if someone has no helmet in a pic it can't get POD but its alright if they are riding without a helmet in a vid?[Reply]
i wonder if you know how to barspin...[Reply]
This vid has several things wrong:[Reply]
No helmet!!!!
Sister's jeans on.
80's metal bandana.
Shitty metal song.
Too many barspins.
No flow to the editing.
Rider has a bag of tricks, but no steeze.
No helmet!!!!
Sister's jeans on.
80's metal bandana.
Shitty metal song.
Too many barspins.
No flow to the editing.
Rider has a bag of tricks, but no steeze.
Sweet riding. Might have been cooler if there where more variety of tricks. Bar spins are only so cool. Whats with the spandex pants.STOP WEARING LITTLE GIRLS PANTS!!!!!! Looks like he is going to the gay bar! Not the best Vod I've seen.[Reply]
sbfleck87 (Jun 17, 2009 at 11:09) (Below Threshold) show comment
How about the Gay Bar Spin![Reply]
just saw that guy a few days ago at Thrash Bike NYC @ Brooklyn Banks, he's got them shit dialled[Reply]
Too slow and not "agressive" style!! Good video and riding, but why VOD???? Wow, I forget, and no helmet. I don´t care about that argument to judge a video but I think PB opened a precedent.[Reply]
wow who cares![Reply]
I think for VOD's it should be mandatory that the riders wear a helmet for the WHOLE video. Not wearing a helmet promotes stupidity, head injuries and brain damage and those are all great ways to give up things like riding your bike, walking, talking and even breathing. Great riding tho.[Reply]
yea your probebly right fugger but don't ever tell that to a BMX thug...[Reply]
bullsh*t, cant people decide on their own if they want to wear a helmet or not...start regulating that then youll start regulating whether the rider has sufficient tread on their tires to be safe in a VOD...[Reply]
I wonder what guys like Stephen Murray and Johnny Waddell have to say about helmets.[Reply]
pretty boring to be honest. fairly decent riding, but it was just so repetive... and his style.. urggg[Reply]
i agree[Reply]
really good rider but video just shouldnt be pod i dont think its to repetitive
and get rid of the metal
great rider tho
really good rider but video just shouldnt be pod i dont think its to repetitive
and get rid of the metal
great rider tho
take out about 1/2 of the vid and then post it again so i will be able to watch the whole thing without barfing my brains out!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!!![Reply]
no doubt he has mastered the barspin. but give him a break... what else can he do look at what he has to work with[Reply]
what happened to the helmet rule?[Reply]
macduff is a dope rider but that video had wayyyy too many barspins in. so boring![Reply]
For all the kids rockin their sister's jeans, did you one day you wake up, or maybe you saw some cute bloke in tight pants, and though, ya, nut smothering tight-ass jeans, that what I want! WTF?[Reply]
IT SHOULD BE CALLED THE BARSPIN COMMANDMENTS[Reply]
is it pants or he painted his legs black?[Reply]
it's boring 360...manual...barspin...360barspin... barspin...manual...nohand...barspin...180...manual...barpin... yawn>[Reply]
lol this guy is a grinder[Reply]
the video was ok....but he neeeds to learn some more good tricks...wayyyy to many barspins[Reply]
that was so sick, loved the cow pants too haha[Reply]
I wonder if he can Barspin?[Reply]
matt you make me laff your tricks are sick your style is fun to wotch and you make me want to ride[Reply]
Good riding, but pants and hair are sickening[Reply]
Monumental rock and street?? LOL!!!! the same tricks all the time..... ;/[Reply]
that was shite[Reply]
chance your name for barspin[Reply]
get a helmet[Reply]
some good riding, but i kinda got tired of seeing the same trick or same shot, over and over again[Reply]
no style.[Reply]
this vid sucks try again later!!!!!!!!!!!!!!![Reply]
yah ur right..... IT ONLY GOT 30 000 VIEWS!!!!![Reply]
k bud we were commenting on this like 10 f*cking days ago stop commenting on old vids (espeacally shitty 1's like this)[Reply]
from the guy who comes here and comments EVERYDAY hahahahahahahahahahah ![Reply]
uhhhhh your the one who comes here everday...it didnt send u a message that says "dickhead commented on your response" so your the one who is always looking...shit head[Reply]
well its his video he gets notification saying that u commented on his video... so he checks it out lol[Reply]
bike buster nobodys else comes back to comment like you. If you had any videos on your profile with comments you would know you DO in fact get a notification. Thanks for trying tho kiddo, maybe next time ha.[Reply]
yeah thanks for trying on the video hahaha maybe next time hahaha...or not[Reply]
maybe next time.[Reply]
hey just wanted to come back and say....MATT MCDUFF BLOWS[Reply]
notgay here nows its true...he really does...most un-deserving VOD right here[Reply]
i am matt macduff lol[Reply]
hahaha so your name is "notgay" but your wearing homo ass pants hahahaha[Reply]
wow you must have really put a lot of thought into that one..[Reply]
ahahaha what a fucking faggot go suck a fucking cock bikebuster[Reply]
his pants r alittle tight[Reply]
to many barspins and he only has about 6 tricks buy good riding anyways[Reply]
did he do enough bar spins?[Reply]
good tho i enjoyed it
good tho i enjoyed it
a b-spin, a 180 and a tuck are not enough to fill a whole video. most boring VOD for years...[Reply]
dirty video. lets see some dirt!! OH WAIt richmondhill blows for dirt jumps.[Reply]
you just don't know where the good jumps are sorry.[Reply]
i know where some are, big trees for example, i just dont like riding with certain faggots. And i said richmondhill not oak ridges, or aurora. There arent any decent jump lines worth hitting thats within a 20 minute drive[Reply]
you don't know where good big trees even is so... Big trees is stoufville, in between oak ridges and richmond hill so either stop complaining or build your own. its simple, jumps don't just grow out of the ground.[Reply]
lol thanks tips. i dont give a shit where big trees is anyways i wouldnt want to ride there now. you still havent proven me wrong if thats what your aiming for[Reply]
that's great, nobody wants you to ride there anyways tips *.[Reply]
good, go have sex with mike reid and all those other fags. good one with the tips also i like how you incorporated that. its still a sick video though lol[Reply]
dont worry justbmx is a dick[Reply]
lol thanks bro but im not worried. i didnt call nobody a dick either[Reply]
OMG BIKE BUSTER STOP COMMENTING WE WHERE ALL COMMENTING ON THIS LIKE 5 DAYS AGO OMG. PINKBIKEE 4 LYFEEE SQUAD UP HOMIES, ROLL OUT.[Reply]
yup uh huh FUCK YOU[Reply]
ahahahahahahhha you mad.[Reply]
by the way mike reid is alright lol[Reply]
ahahahahahah you gay and like 13 ahahaha[Reply]
no flow no style just a load of barspins[Reply]
woooooowww never laughed so hard after reading all these bullshit comments. Most of u are all a bunch a wanabe douche bags.[Reply]
tuck no hander of a curb now thtas inpressive[Reply]
he does it like it is his night job[Reply]
This is Mat's worst video... his sumer and spin edits are much better than this/.[Reply]
VOD !!!!!![Reply]
congrats on the VOD Matt[Reply]
I can't believe you guys are complaining about tight pants . Who cares what he wears it's about the riding not what you wear.[Reply]
i do believe that the tuck nohander off the bus would make a sweet pod sick ridding on the 26's props.[Reply]
i was at that church today[Reply]
homeless? helmet rules[Reply]
Skinny pants. barf.[Reply]
pretty sick man. for a second video alot more varity is required. Seemed slightly repetative.[Reply]
this edit was awesome. i liked the quiet music. ha. i suck and like anything you do is cool to me[Reply]
All it was was bar spin, bar sipn, bar spin 360 abother bar spin it was gay...[Reply]
Amazing vod all the way F*ck ya[Reply]
I was quoting the idiot, hence the brackets, I was defending BMX so just calm down.[Reply]
no style whatso ever! and i just love to barspin!! ha[Reply]
rhis guy is a bar spiner lol[Reply]
barspin, barspin, barspin, boring boring[Reply]
Sick!!!! guy has skills. its sick to see bar spins that clean for the huge bars[Reply]
SICK riding matt![Reply]
What a hippie.[Reply]
mau12 (Jun 17, 2009 at 10:14) (Below Threshold) show comment
yeaah, a haircut, and new pants, i mean, wtf was that?[Reply]
dude fuck you...look at the props you got on that response above...thats how much people agree with you!!!!! haha you suck ass[Reply]
wow bikebuster comment on some good things!!!!!! but true[Reply]
ok first of all to bikebuster....anyone who actually gives a fuck about how many props they get on pinkbike comments has no life...its a stupid feature. and second of all... why wouldn't you just get a bmx if youre going to ride street...i used to ride park on a mtb but its really stupid looking back on it all. BMX[Reply]
hes sponsored by a mountain bike company and has been riding these bikes since way back.[Reply]
f*ck whoever says too many barspins or w/e, theyre dialed I wish I could throw bars everywhere. nice vid, id like to see anyone here bashing this guy do better[Reply]
theres something about that kid that just makes me not like him[Reply]
I think boring is the thing... jejeje. He's got talent, but the vid makes no favor to him. Just pay more attention to the vdo edit and the music. The tight pants is up to him, but the helmet... surely the helmet would be a great idea. Nice riding though.[Reply]
wow 18 barspins do sumit different please[Reply]
its street, what other tricks would you have liked to see?[Reply]
seriously do make a list of tricks you would have liked to see at theses spots.
seriously do make a list of tricks you would have liked to see at theses spots.
ermm well just more veriety realy[Reply]
there where a few whips in there. what do you want him to do more? oh but then ill have all of pinkbike going on about how he did to many whips so really watch the video again and tell me what he DIDN'T do street wise.[Reply]
look how many comments you got saying about how many barspins there was thts all im saying man.[Reply]
hahaha so don't say do something different when he had a variety of tricks with a bunch of barspins.[Reply]
well it was mainly just barspins so the point i was getting across was the fact it was boring seeing that many barspins :\[Reply]
and i was trying to get the point across that you are telling him to do something different when he did with additional barspins.[Reply]
additional nah he did loads of barspins with the odd 180/360 or tail whip but anyway.[Reply]
dont ride street then if its so shit in for it.[Reply]
dont ride street then if its so shit for it. #[Reply]
clearly nothing is getting trough your head i give up.[Reply]
care.... still does too many barspins.[Reply]
Skinny jeans - PUFFTER[Reply]
thers nothin wrong with them i think ur the dumb ass with ur trackies that wud just get caught in the chain haha[Reply]
yeah nothing wrong with them, except the fact they were made for women nd i dont wear trackies.[Reply]
well i was just lookin at ur pics nd its full of trackies haha[Reply]
WOW DUDE you tottally dialed the 180 bar last time i saw you at aurora park you were like just learning them sick video dude[Reply]
if he wants to ride something he will ride it aha[Reply]
300th comment![Reply]
why are you posting s**** like "you should ride BMX" or "no helmet" what are you 13 or smtg? street vids dont get to be VOD's often, so just enjoy it, "no style" huh? it's the style he prefers, not YOU, just deal whit it, personaly for me it is awesome, good riding and superb muzic )[Reply]
matt you are my hero.....[Reply]
i mean wear it at all times[Reply]
biker version of chuck norris, thats how much of a beast he is[Reply]
can you do anythin but bar spin??????[Reply]
I'm a fan of wide bars, but Damn.[Reply]
Fair enough its good riding, but jeez bar spin after bar spin :/[Reply]
Great video. You sure can ride![Reply]
Why is he using his Argyle as rigid as possible? is that way better for street?[Reply]
good video dstarted to get anoying tho coz all u do was like bar spins, took no off bus was sick tho[Reply]
Matt Macbarspin[Reply]
the barspins were starting to get really anoying.[Reply]
barspin mania, good video[Reply]
cool riding but wear a helmet. Cool shirt too[Reply]
This is such a crap VOD. Some wannabe bmxer riding a brakeless mountain bike with suspension doing street.[Reply]
right, cause 26 inch wheels make it a mountain bike? my bad, maybe your just pissed cause hes probably about 900 times better then you at everything and your just a little pansy so you hate on other peoples videos?[Reply]
Um yeah 26" wheels are for MTB's and 20" are for BMX. Duh![Reply]
I just think that all these BMXers on MTB's should just man up and admit that they are just attempting to form a new sport to avoid the reality that the average BMXer is better than the average MTB street rider or dirt jumper or whatever their "new sport" is called.
I just think that all these BMXers on MTB's should just man up and admit that they are just attempting to form a new sport to avoid the reality that the average BMXer is better than the average MTB street rider or dirt jumper or whatever their "new sport" is called.
o yeah! well we beat you in the revolutionary war sucka![Reply]
he is on 24, so fuck both of you, 24 ponys for life[Reply]
Why is he using his Argyle as rigid as possible? is that way better for street?[Reply]
holy shite were do I get a pair of those pants...I kinda like the no handers...[Reply]
That dumpster jump thing was sick!! So were those tailwips.[Reply]
he sucks[Reply]
1: since when does a headband count as a helmet?[Reply]
2: f*ggot ass jeans
2: f*ggot ass jeans
its called hesh fool, and jeans can't have a sexuality[Reply]
bikebuster (Jun 17, 2009 at 14:47) (Below Threshold) show comment
they can when that mother fucker is wearing them!!!![Reply]
dude bikebuster, matt can ride the fuck out of his bike, u from the look of things can only break the fuck out of ur bike. show some respect to those better than u[Reply]
Bikebusters a loser[Reply]
wow you guys make a great couple!!!!! ahhh fuck both of you!!!!!![Reply]
to many barspins[Reply]
guy is awesome...think how awesome he could be if he had better range of movement by not wearing his little sisters jeans[Reply]
nice vod. how many of you realized he was riding break less.give the guy a break he not riding for you who cares how he looks he a good ride.[Reply]
riders insane but i like how hes riding mtb and the profile says just bmx[Reply]
kewl but repeatative gud rider but i was getting a bit sik of bar spins[Reply]
dammmm man thats awesome :X props to rider :X[Reply]
nice the vid is asome vod[Reply]
omg barspin heaven :L[Reply]
SOOOOOOOOOOOO GGGGAAAAAYYYYY!!! HESHER FAG[Reply]
ya one question how do u do barspins any trick tips[Reply]
that was a pretty sick vid[Reply]
Matt Macduff A.K.A "Mr Barspin"[Reply]
not a fan of the tights but crazy skills[Reply]
What a tool.[Reply]
he has one of my dream bikes[Reply]
wow u really like ur bar spins[Reply]
dude your jeans are so tite i think im going to have a coma[Reply]
to many barspins but great vid[Reply]
sick video but personnaly i think too many barspins[Reply]
is that a pinscher frame?[Reply]
Wow man! I love your no hander ; )[Reply]
b-spin city![Reply]
tuck no off of a curb...wtf![Reply]
barspin much?[Reply]
Breakless hell yeah![Reply]
Nice ride man![Reply]
i thoguht you need a helmet to get VOD[Reply]
so did i[Reply]
enough bar spins[Reply]
Ultra brutal riding, but he looks like homeless..xD[Reply]
badass pants[Reply]
no - bad asspants[Reply]
he loves his barspins.....but so would i if i was that good at them[Reply]
You do really love barspin[Reply]
well would you look at that. his bike is 4 inches too big.[Reply]
you ride a monkey bike[Reply]
sick vid a over doing the bar spins dont you think[Reply]
to many barspins[Reply]
sick but to many barspins[Reply]
VOD!! good job matt[Reply]
Thats insane![Reply]
He should work on getting his tricks a bit smoother. There great tricks but if he could smooth them out a little that would be good.[Reply]
Every time i see u i touch ma self[Reply]
nice man[Reply]
yo this is filmed in heartland?[Reply]
its a good vid but why soo mant barspins , i always new what was going to hapen for each trick, BARSPIN[Reply]
nice video[Reply]
whats with the hating on barspins4 there a sweet trick??[Reply]
Nice vid =D really good,, thoes tires look faat^^[Reply]
TOO MANY BARSPINS!!![Reply]
Pretty sick riding with no brakes.[Reply]
what the f*ck did his mom try and bleach his jeans or something?[Reply]
good ridin but the music was shite![Reply]
samtheman66 is oviusly compinsating for something just because he wheres tight pants dosent mean hes gay[Reply]
amazing riding a little to many barspins[Reply]
Some random hippie kid wearing his lil sisters pants and doing barspins = shit vod[Reply]
Also riding brake-less is stupid...
Also riding brake-less is stupid...
your scum you heartless cunt[Reply]
garrett reynolds on mtb..... awesome[Reply]
does his fork do anything? he is basically running it rigid[Reply]
nice vod but way to many barspins for mee.[Reply]
personaly i dont like landing flat on concrete -obviously this guy does though. might as well have been on a bmx[Reply]
cool tricks, but i think her style isnt good[Reply]
its he.. mat.[Reply]
maybe with a shorter bar it will be better[Reply]
dude the wide bar makes his barspins look soooooo nice.[Reply]
put a helmet on![Reply]
nice video!!!maybe to much bar spins[Reply]
representin york region baby solid stuff matt[Reply]
nice video .... good riding[Reply]
damn, its realy good streeter, i want to say vod[Reply]
sick ridin but thoes shoes suck for biking i hav them and if your riding breakles thay suck:P[Reply]
Sweet Vid[Reply]
schoolbus tuck no hander was epic !
schoolbus tuck no hander was epic !
Riding in my home town thanks man[Reply]
why dont you ride bmx? ad its the garret reynolds of the mtb world :L[Reply]
lol that will wear his headset out with all those repetitive barspins!!! XD[Reply]
duuuuuuuuuuuuuuude!!! that was sick. but, get a haircut, hippie![Reply]
holy balls that was dope! you guys are soo BUM FIGHT[Reply]
so much Hate...I love it. Pinkbikes lame[Reply]
here come the neg props![Reply]
26" inch wheels should stick to dirt...
unless your a roadie
26" inch wheels should stick to dirt...
unless your a roadie
hmmm thats why he rides 24" i guess[Reply]
and roadies ride 28" btw lol[Reply]
what are them forks i fink thay are the same as mine[Reply]
congrats matt sick riding[Reply]
Barspin ?[Reply]
niice pants :S[Reply]
well i liked it and im not gay so ...[Reply]
Good vod but i would like to se a more verity of tricks.But i would say the trick that he has learnt are A*.[Reply]
oh and i live there and theres no gay bars around[Reply]
HE GOT VOD!!!!!!!!!!!!!![Reply]
that was intense[Reply]
shittie jeans...naaa[Reply]
omg vodd this guy is my inpiration[Reply]
AWESOME VOD[Reply]
good vid a lot ans l and lots and lots of bare spins[Reply]
manual at the end was nice, ok vid all about fun , tempted to get a 24 for arseing about on myself[Reply]
wtf... dis sht off da chain[Reply]
barspins are gaaaaaaaaaaaaaaaaaaaaaay[Reply]
TO DOPE... Justin ur the man[Reply]
Meh to many barspins but he's the biking definition of hesh lol[Reply]
man that was sick..what kind of forks were those?[Reply]
Marzo 4x[Reply]
lam3 5 trick comandments... buy a bmx[Reply]
is that 24 or 26 inch?[Reply]
very good riding...
very good riding...
its about time matt got vod.. great job natt.[Reply]
fuck man nice riding. good video too[Reply]
Skinny jeans,long hair, repetetive tricks ! boring oh and i get the picture U CAN BARSPIN!!!!![Reply]
Ridiculous! SIICKK[Reply]
Dude, PYRAMID THEROM? We just played a show with them, and gunna play another.[Reply]
wow ausome riding[Reply]
master of barspins![Reply]
tht video is cool but hes only doin tailwhips, bars, spins nd tucks[Reply]
vodd sick vid mann[Reply]
me too aha[Reply]
get a haircut ya hippie[Reply]
your just jealous, you wish you could shred as hard as him.[Reply]
i like the jeans[Reply]
great VOD[Reply]
very nice riding dude![Reply]
but, euhm the pants is weird :p
but, euhm the pants is weird :p
toooo many barspins.[Reply]
nice riding, nice shirt[Reply]
what kinda bike[Reply]
good vid man but yeah toooo many barspins[Reply]
yeah!!!!! great rider...bar and tuck-drop!!!![Reply]
cut down on the bar spins;
but that bike must weigh a ton
good on ya
cut down on the bar spins;
but that bike must weigh a ton
good on ya
I didn't know Weird Al Yankovic had street Skillz.... Nice Vid![Reply]
I love this Vid! so nice music, sick bars and last tailwhip. the best VOD for a long time.[Reply]
Barspin Mcgee over here![Reply]
this guy kicks ass[Reply]
Wow, brakeless!!!!!![Reply]
how wide this bar man?[Reply]
LOVE IT! VOD DEFINATELY![Reply]
Some random hippie kid wearing his lil sisters pants and doing barspins = shit vod[Reply]
Also riding brake-less is stupid...
Also riding brake-less is stupid...
that random hippie kid rides for dobermann.[Reply]
sic vid[Reply]
this is the worst VOD ive ever seen!!!!!! fuck this shit, and anyone who thinks that this guy is hot because he can do a fucking barspin is soooo fucking screwed!!!![Reply]
gayest vod ive ever seen .....[Reply]
everything about it was ugly. i fucking hate mountain bike street, ride a fucking bmx and stop pretending. ugly. very fucking ugly.[Reply]
hes fucken amazing,and ive seen him ride bmx in other vids.and hes better than you[Reply]
Boy, if i were you Rory id be really insulted, heyhey just said he's better than you.[Reply]
WHO CARES.[Reply]
the whole website, if you dont care dont post.[Reply]
OMG PINKBIKE 4 LYFE !~~![Reply]
IMA NEG YO ASS![Reply]
47.7. POD[Reply]
i just rode with him at the thrashbike contest[Reply]
dang that guy is so hesh[Reply]
MATT MACDUFF IS GOD WHEN IT COMES TO BIKES[Reply]
MATTS INSANE but wheres the flamingo?[Reply]
That was one nasty tuck off that bus roof[Reply]
26" or 24" ??[Reply]
finally a good vod[Reply]
tighte jeans[Reply]
such a sick vid[Reply]
sick song[Reply]
HA the song sucked ass[Reply]
ya matt and justin![Reply]
good tricks but really cut your hair[Reply]
and...mstts good to[Reply]
sick m8[Reply]
holy shit sooo good[Reply]
I knew it was going to be VOD![Reply]
GAY GAY GAY GAY GAY, wayyyyy too many barspins, and not very smooth at all.[Reply]
uhhhh... that was harsh...[Reply]
neg prop me if you want but his moves are too predicable and i dont really like him[Reply]
i wanted to, and i did neg prop you[Reply]
ok then[Reply]
THATVIDEO IS GAY![Reply]
get a bmx mtb are lame at street it looks so dumb your tryin to be a bmxer but still riding is kill.[Reply]


text:
- Description
IWC 91 Pts - According to International Wine Cellar - Bright purple. Powerful, spice-accented scents of cassis, olive paste, violet and woodsmoke. At once rich and lively, offering sweet dark berry compote and peppery spice flavors, along with a smoky overtone and a hint of cola. Precise and sharply focused on the subtly tannic finish, leaving intense berry skin, bitter chocolate and black pepper notes in its wake.
Winemakers Notes - The aromas are classic Bien Nacido and classic cool climate Syrah, spicy, peppery, clove, nutmeg, dried raspberry and just enough of that thyme and sage character that comes from the stems.
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Varietal/Type Syrah - Shiraz gtin No Brand Qupe Size 750 ML Standard Rating 91 Points
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January 17, 2017 - 10:00 GMT
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President Obama has been on a mission to release the remaining inmates before Trump takes office.
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Oman's Minister of Manpower is expecting Omani employee numbers to increase following the introduction of the ministry's development programme.
January 16, 2017 - 11:00 GMT
The 10 have been released from Guantanamo Bay and received by the Sultanate at the request of the US government, a senior official at the ministry said in a statement earlier today.
January 11, 2017 - 17:34 GMT
With the football World Cup set to feature as many as 48 nations from 2026 onwards, as announced on Tuesday by the sport's world body FIFA...
January 11, 2017 - 10:14 GMT
Twitter users have been calling for action to combat high youth unemployment in the sultanate.
January 11, 2017 - 08:00 GMT
Oman has refuted a Reuters report claiming that it is courting Gulf states for millions to boost its foreign exchange reserves.
January 10, 2017 - 09:30 GMT
The British oil and gas company will undertake the engineering, procurement and construction of the Salalah LPG extraction project in the southern part of Oman.
January 08, 2017 - 16:09 GMT
No matter where Ali Al Habsi goes, he is guaranteed the support of the people of the Sultanate of Oman, who've always backed him to the hilt during his lengthy career overseas.
January 08, 2017 - 15:25 GMT
Oman's new national football coach, Dutchman Pim Verbeek, who arrived in Muscat earlier this week to take charge of the Red Warriors, wasted little time to get into work mode.
January 08, 2017 - 12:00 GMT
Trade union officials and experts in Oman predict that the 'expat exodus' that began in 2016 will continue this year.
January 08, 2017 - 10:00 GMT
Iran's exports to Oman have more than doubled in four years thanks in part to the launch of a direct shipping line between the two countries.
January 05, 2017 - 10:00 GMT
The Sultanate's ratings reflect its low public and external debt, strong balance sheet and high per capita income, balanced against its double-digit fiscal deficit and a very hydrocarbon-dependent budget and economy.
January 03, 2017 - 11:00 GMT
Due to the worsening economic situation around the world and low oil prices in the region, overall sales in room rates in Oman's four- and five-star properties continue to decline.
January 02, 2017 - 06:01 GMT
Oman plans to take on the OMR 3 billion deficit with lower public sector recruitment, continued austerity measures, a review of subsidies and privatization of government assets.


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The Washington Ballet's The Nutcracker, Set in Historic D.C.
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A wonderful production, a lovely afternoon, and an especially stunning second half of the performance!
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A classic Washington DC holiday performance. The costumes were great, the scenery beautiful and the dancers graceful. We had great seats and the whole process was very easy. Just showed a photo id at Will Call.
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Just fabulous. The dancers, the sets, the costumes. Even the unorthodox aspect made it fun. One of my favorites. Don't miss! Katie-jane
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This was a great outing, from start to finish. The premium seats at Warner were great -- I will purchase these seats again -- worth the extra $$ (I'd not heard of them before - even if I had, I probably wouldn't have sprung for the extra $$ if...continued
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