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Nov. 29, 2012
Colorado State at Bowling Green | Game 6
Colorado State (2-3) travels on to Bowling Green, Ohio, to face the Falcons (3-3) at the Stroh Center (4,387) on Saturday. Tipoff is set for 2:30 p.m. MT.
The Rams next three away games are at opponents from last season. CSU lost to Bowling Green and Colorado at home last year, but earned its first win of the 2011-12 season over Tulsa at Moby Arena.
With the return of two-time all-conference selection, Sam Martin, and the reigning Mountain West Sixth Player of the Year, Meghan Heimstra, the Rams will look to improve upon last season's 13-17 record. Sophomore LaDeyah Forte leads Colorado State from the point guard position. She finished second in assist-to-turnover ratio in the MW in her rookie year.
Bowling Green lost its first home game Wednesday vs. Temple, 70-56. The Falcons are now 2-1 at the Stroh Center.
The game will be broadcast live on AM 1410 KIIX. Matt Wozniak, now in his fourth season with the Rams, calls all the action. Live game video will also be available via Rams All-Access subscription on CSURams.com, and for the first time, fans will be able to listen to every Rams' game for free on Rams All-Access.
Scouting Bowling Green…
- Head Coach Jennifer Roos is in her first season at the helm of the Falcons' program. She spent 11 seasons as an assistant, including eight as the associate head coach before being promoted upon former Head Coach Curt Miller's departure to Indiana.
- The Falcons advanced to the WNIT last season, falling in the first round to VCU at home. BGSU finished 2011-12 with a 24-7 record.
- BGSU was picked to finish second in the East Division of the Mid-American Conference. Alexis Rogers and Chrissy Steffen were two of the four returning starters from Bowling Green named to the East's Preseason All-MAC team.
- Steffen leads the team in points per game with 12.3, followed by Jillian Halfhill and Danielle Havel with 9.5 and 9.2, respectively. Havel leads the team on the glass, with 6.0 rebounds per game, with Alexis Rogers just behind with 5.8 boards.
- Temple was hot, shooting 61.5 percent in the second half Wednesday night, handing Bowling Green its first double-digit loss since the Stroh Center opened in 2011. Steffen and Rogers were the two top scorers for the Falcons, with 13 points apiece.
Series vs. the Falcons...
Saturday's meeting between Colorado State and Bowling Green will be the second game between the two schools. This is Head Coach Ryun Williams first contest vs. the Falcons.
The Rams are 0-1 vs. BGSU overall, with a loss last year at Moby.
Last time vs. Bowling Green...
The Colorado State women's basketball team lost to the Bowling Green Falcons, 70-57, on New Year's Eve at Moby Arena.
The Rams (3-10) started in a strong fashion with a 13-4 run to begin the game, but Bowling Green (10-3) came back even stronger to lead by seven at halftime.
Sophomore Sam Martin had 12 points and four rebounds. Senior Kim Mestdagh couldn't find her hot-spot for the game and only ended up with seven points. Junior Meghan Heimstra recorded nine rebounds and 12 points, playing 27 minutes.
Bowling Green had 12 second-chance points off of the Rams' 17 turnovers.
Playing in her first game of her career, freshman Hanne Mestdagh got to see some action for five minutes.
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'The Voice' Season 8 Judges Announced: Christina Aguilera Is Back!
Get ready, 'The Voice' fans: Christina Aguilera is coming back!
Get ready, 'The Voice' fans: Christina Aguilera is coming back!
Christina Aguilera, who gave birth to a baby girl on Saturday (Aug. 16), has officially released her daughter's name, Summer Rain Rutler!
It's a girl for Christina Aguilera!
The 33-year-old singer gave birth to a baby girl on Saturday, Aug. 16, according to Us Weekly. Aguilera underwent a C-section at Cedars-Sinai Medical Center in Los Angeles.
Maternity photo shoots are pretty common these days, but Christina Aguilera took the tradition to a new level with her bare-body spread.
While many soaked up the sun, Christina Aguilera celebrated the first day of summer (June 21) by showing off her growing belly on Twitter!
After yesterday's announcement that Gwen Stefani will be replacing Christina Aguilera on NBC's 'The Voice,' Christina took to Twitter to talk about what she has planned during her time away from the reality competition show.
NBC's 'The Voice' will be welcoming a new face to the judges panel for season seven: Gwen Stefani! Stefani will be sitting and slamming buttons in Christina Aguilera's chair, who is currently pregnant with her second child and will be taking time off to care for the new baby. Season seven is scheduled to begin filming in June and run through the fall 2014 television season.
Finally! Christina Aguilera, pregnant with her second child, which she revealed is a girl, shared a photo while in NYC with her fiance Matthew Rutler. We can finally see her baby bump, as she put it on full display in the pic, something she hadn't done up until now.
Stunning singer Christina Aguilera is expecting her second child and guess what? She's having a baby girl.
It's another major life event for singer Christina Aguilera!


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Earth Bag Architecture Workshop
Biko Casini
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San Francisco, California
London, United Kingdom
Florence, Italy
Event Details
Be prepared to get hands-on, designing and constructing multiple earth bag structures. Learn the principles of the arch, earth bag construction, dome building, and cistern/water collection technologies.
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2105 St. Cyr
2105 Saint Cyr Avenue Southeast
Saturday, June 1, 2013 at 9:30 AM - Thursday, June 6, 2013 at 5:30 PM (MDT)
Add to my calendar
Biko Casini
Biko was trained at a young age in masonry by his father. Together they worked restoring plantation homes and churches in the South. He spent years as a student and employee at the Ecovillage Training Center, where he worked to design and build the ETC campus. He studied sustainable building and development in South Africa, and with sixteen years of natural building experience, he has built with stone, cob, straw bale, adobe, straw clay slip, and cordwood, in the U.S., South Africa, Italy, India, and Ghana.


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The ocean and tropical views from the Pualani Beach House make this Hawaiian home your true paradise. Located in the gated community of Kapoho Beach Lots on the eastern tip of the Big Island, snorkeling, swimming, bicycling, and hiking are nearby!
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The RetroEngine Sigma sounds like it will make the process of running classic games impossibly easy.
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Hotel Bon Alpina, Innsbruck
- Free WiFi in lobby
Main amenities
- 95 smoke-free guestrooms
- 2 restaurants
- Indoor pool and outdoor pool
- Breakfast available
- Ski storage
- Fitness center
- Garden
- Arcade/game room
- Tour/ticket assistance
For families
- Free cribs/infant beds
- Private bathroom
- Garden
- Hair dryer
- Flat-panel TV
- Satellite TV service
What's around
- In Igls
- Patscherkofel Mountain Bahn (0.3 mi / 0.4 km)
- Patscherkofelbahn 1 (0.3 mi / 0.5 km)
- Olympia Express Gondola (1.1 mi / 1.8 km)
- Innsbruck Olympic Sliding Center (1.2 mi / 1.9 km)
- Patscherkofelbahn 2 (1.7 mi / 2.8 km)
More great choices
At a glance
Key facts
Hotel size
- This hotel has 95 rooms
- This hotel is arranged over 3 floors
- Check-in time starts at 2 PM
- Check-out time is 11 AM
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- Children (2 years old and younger) stay free when occupying the parent or guardian's room, using existing bedding
- Pets allowed (dogs only) *
- Free WiFi in public areas
- WiFi in rooms *
- Free nearby parking
Other information
- Smoke-free property
Nearby Three Star Innsbruck hotels
In the hotel
- Buffet breakfast (surcharge)
- 2 restaurants
- Bar/lounge
- Room service (during limited hours)
- Indoor pool
- Outdoor pool
- Ski storage
- Fitness facilities
- Steam room
- Sauna
- Downhill skiing nearby
- Arcade/game room
- Billiards or pool table
- Tours/ticket assistance
- Number of buildings/towers - 3
- Garden
In the room
- Private bathroom
- Shower only
- Hair dryer
- Flat-screen TV
- Satellite TV channels
- Desk
- WiFi (surcharge)
Top Innsbruck hotels
Recently reviewed hotels in Innsbruck
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"Everything was great!"Dec 9, 2016
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"quaint, great food, i would highly recommend this hotel to a fellow traveller. especially loved the great pillows. "Dec 8, 2016
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"It was such a great time staying there and feels like a home! Highly recommended and you will find all the details they paid attention to to make the best for you, the sauna house…"Dec 5, 2016
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"My husband and I loved our stay so much. We were only there for one night and can't wait to come back. They have the most comfortable beds in Europe! The bathrooms are in new…"Dec 3, 2016
Also popular with travelers from the USA
Special features
DiningOnsite venue - This restaurant specializes in international cuisine and serves lunch and dinner. Open daily.
Hotel Bon Alpina, Innsbruck's small print
Also known as
- Bon Alpina
- Bon Alpina Hotel
- Bon Alpina Innsbruck
- Hotel Bon Alpina
- Hotel Bon Alpina Innsbruck
- Bon Alpina Hotel Igls
- Bon Alpina Igls
Reservations are required for massage services and can be made by contacting the property before arrival at the number on the booking confirmation.
Mandatory fees
You'll be asked to pay the following charges at check in or check out:
- Tourism fee: EUR 1 per person, per night
Optional extras
Pets are allowed for an extra charge of EUR 6.50 per pet
WiFi is available in guestrooms for EUR 1,00 per night (rates may vary)
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.
Recent reviews
Good 3.9 /5 from 34 reviews
Nice hotel, the location is convenient and the rooms are good size and clean. The swimming pool is not very big and the water is quite cold, not ideal for kids. The food is pretty good with a friendly service. Honest value for the price.
W checked-in very late in the night (1 a.m.), the staff was there, I guess there is always some one there. The room was huge,and clean. But there is no a/c and the temperature was almost 30 to 30++ degrees, it was hot in summer. It can be just us, but the waiter have we seated next to a European family who clearly have not seen any Asian in their lives, they keep staring and made us feel uncomfortable. Table so closed together that every time someone walks pass they kind of hit you in the back. The hotel is in Igls, there are buses to Innsbruck every 10-20 minutes. But if you want to travel in Innsbruck, my advice is tpo stay in Innsbruck, it's not that different in price.
It was a pleasant stay at Bon Alpina. Hotel is easily accessible from the main highway. We stayed there for two nights and we were satisfied with the overall service. There's a swimming pool and sauna but get there in time before it gets crowded. Although breakfasts were nothing special and we missed simple things like tomatoes, than dinner was great.
Is the description of this hotel not correct? Tell us


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A Day In the Life of the Fizzy
Sad DayNovember 22nd 2010 5:24 pm
[ Leave A Comment | 16 people already have ]
It's a sad day here, pups. Grammy's hair started falling out, so Momma went over to her house and cut it all off. Grammy was crying a little bit, but Momma tried to cheer her up by talking about what it might look like when it grows back. Maybe she'll be a stunning red head or a bodacious blonde! I don't really know what those words mean, but Momma was sad when she came home. She hasn't leaked, though. She keeps reminding herself about those really good test results, and she says Grammy looked really cute in her turban.
Leave A Comment | 16 people already have
Sorry Fizzy, somehow the graphics didn't show up...but they're here now and in Austin's msg. above. Sorry.
Prayers for Grammy
Fizzy Gammy, you's the same beautiful, loving human with or without hairs! We's pups doesn't cares 'bout outward 'pearances--we's loves you no matter what! Hugs & licks!
Yeah, its hard when that happens...but they really do have nice turbans, hats and scarves. Growlmy tried to have a nice hat to match all of her good outfits for when she was out of the house, and the same for turbans when she was home. She has a whole box full of them! Hope she doesn't evfur need them again!
Hugs & Kisses
Sending lots of hugs and good healing thoughts to your Grammy, Fizzy!
Fizzy tell your Grammy that furs dont care what we look like that you will still send her lots and lots of kisses.
We will keep her in our prawyers!
Woof Woof Woof, Buddy, Molly & Scooter
Aw pals thanks a lot. Momma always appreciates the nice words cause they cheer her up and help her be strong for Grammy. MJF, I hope and pray your Growlmy never needs those hats and stuff ever again, too! DOWN WITH CANCER!!
Sending prayers and westie kisses to your grandma.
Fizzy tell your Mommy that we're thinking about her and Grammy. We'll keep those prayers coming!
we are thinking of your Grammy, with or without hair your Grammy is still the same and she will be just fine! Hugs to your Mom too!!
GRRRRRRRRR.....tu dat bad cancer stuff, bud YAY tu yur Momma, Fizzy, fur helpin' yur Gwammy wif hur hair an' fur bein' dere fur hur. Dat r whut famblies du. It r all 'bout da wuff ♥ ♥ ♥ ♥ ♥ ♥ ♥
Growlmy can still keep all her 'head gear' in the box!
She got a good report today...doesn't need to go back for another 6 months!
Hope that when your Grammy is done with the chemo junk, that she will get good reports, too.
Pawyering for a great outcome.
When will the chemo be done, anyways? (Or at least, what is the plan...? Most seem to be about 4 - 6 months long.)
OH MJF!!! That's great news! I'm so happy for you and Growlmy!! Oh joy joy joy!! Do you see my schnauzie butt wiggling with happiness!!?!!?!
Momma estimated Grammy's chemo to be done February 21. That's IF all goes according to plan and she goes every 3 weeks on the nose. Her next round is this coming Monday, and Momma is going to go with her this time and stay with her. She felt real bad she couldn't go the first time.
I can see your comment! Did the flea stuff get to work! BOL!
Growlmy mostly had friends go with her to chemo.but they didn't stay! Some of her chemos went for 6 - 8 hours!
A couple of times Pawppy could get off work to go with her.
It sure is nice when there is someone there to be company and a support.
Feb 21...seems like a long ways off...but it will get here, those weeks just keep going by...faster than we want them to sometimes! Your Grammy will be finished just in time for the beautiful days of spring...and if all goes well, it will be like a new start for her, too!
Lots of Westie kissies and prayers on the way......
We will keep sending those good thoughts and prayers your way. Hoping everything goes according to the plan and Grammy's hairs will all grow back.
We said a pawrayer for your grammy!


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Everki lifestyle bags
Ilse Jurriën : November 21th 2005 - 02:54 CET
Everki lifestyle bags :
Tritton today introduced its new line of Everki lifestyle bags. Designed for consumers seeking innovative technology and transport solutions, Everki bags are fashionable, rugged, easier to transport, versatile and multi-functional. The Everki lineup includes small, highly portable bags, cases, backpacks, briefcases and travel duffels and is created for a wide variety of on-the-go applications and digital products. Whether its laptops, digital cameras, MP3 players, PDAs, cell phones or gaming devices, Everki provides an intelligent and protective organizational system for electronics and paperwork to keep users on the go, while providing security and easy access to anything they may need inside.
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Consumers are spending top dollar for new digital cameras and accessories. Everki bags protect consumers' investment and organize all the accessories they'll need to capture that memorable moment anytime, anywhere. Models include:
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Everki manufactures movement-focused gear designed to carry and protect the equipment, data, and intellectual property. Everki bags combine comfort, convenience, durability and style and feature contoured zipper pulls, padded handles, and cushioned contact points. Everki bags offer smooth zipper lines, stash pockets, top load design cuts and quick snap buckles, which provide easy access to files and electronics. They are constructed with tough, reliable materials, robust padding in side walls, computer nests, and sturdy zippers with smooth lines, classic colors, and unique features to blend distinctive function with impeccable looks.
About Tritton Technologies
Tritton is based in Vista, California and is a manufacturer of innovative and unique networking, storage and computer peripherals. Tritton provides its consumers with the latest cutting edge technology combined with the highest quality of manufacturing and customer service. The products are designed to be user-friendly insuring long-term customer satisfaction, while delivering first-to-market solutions.
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Digital cameras
Mobile phones


text:
RENEE MONTAGNE, host:
It's 8 o'clock at night. You have a stack of dirty dishes in the sink, a pile of paperwork on your desk and your kids want you to read to them. Guess what? There's an app for that. Okay, not the dishes. But you can download a children's book app to your Smartphone or iPad. Enhanced children's e-books include narration, animation and interactive features.
As NPR's Lynn Neary reports, some kids are getting their very first exposure to books on a digital device.
LYNN NEARY: Michel Kripalani is deeply invested in Dr. Seuss these days for two reasons. His company, Oceanhouse Media, has the rights to develop the works of Dr. Seuss as digital books; everything from "Green Eggs and Ham" to "The Cat in the Hat." Kripalani also has a two-year-old daughter, Kentia, who loves Dr. Seuss, especially on her father's iPad.
MICHEL KRIPALANI (President, Oceanhouse Media): Boy, she can navigate on that thing. It's incredible. There's something about a child's ability to navigate by touching what they want and I believe that's the magic here. It's just that the child is able to touch the tree, or touch the bird, or touch the word that they don't know and that's really one of the things that just changes everything.
NEARY: What's that?
Ms. KENTIA KRIPALANI: Kitty-kitty.
Mr. KRIPALANI: The kitty-kitty. Can you touch the cat?
Unidentified Woman #1: Cat.
Mr. KRIPALANI: Good job.
(Soundbite of a cat)
Ms. KRIPALANI: Meow.
(Soundbite of an e-book)
Unidentified Woman #1: No, Pat. No.
NEARY: Kripalani doesn't consider himself an expert on reading. He began his career as a videogame developer. But he says his team was very aware that Theodor Geisel, aka Dr. Seuss, cared deeply about literacy. So in developing digital versions of books like "The Cat in the Hat," they wanted to use the interactive features to help children learn to read.
Mr. KRIPALANI: And as the app is reading the book, the individual words are highlighting. So the child is getting an association between what they're hearing and the actual word that's being spoken at the time. Or they can also touch on any of the pictures and they get a picture-word association. So if the child taps on cat, for example, the letters C-A-T float up and the narrator speaks in a clear voice: Cat.
NEARY: With the e-book market so hot right now, a lot of people are eager to get in on the ground floor. Rick Richter left the traditional publishing world, to found Ruckus Media, which develops digital versions of well-known kids' books, as well as brand-new book apps like "A Present for Milo."
Mr. RICK RICHTER (President/CEO, Ruckus Media): What a two to four-year-old wants in an app really is to poke and be satisfied and really a very high degree of interactivity. So "Milo" has 80 different touch points and 125 different animations. And they're randomized, of course, so every time the child enters it's a different experience.
NEARY: "A Present for Milo" begins simply enough with a story about a cat and a mouse.
(Soundbite of e-book, "A Present for Milo")
(Soundbite of knocking)
Unidentified Man #1: Who's there, there, there?
Unidentified Man #2: Milo, that's who and away they go.
NEARY: Words appear as the narrator speaks them and illustrations come alive. When touched, a mouse squeaks.
(Soundbite of laughter)
NEARY: A plane flies.
(Soundbite of an airplane)
NEARY: A piano plays.
(Soundbite of a piano)
NEARY: Other book apps developed by Ruckus are less interactive but they might offer other options: substituting a well-known actor's narration with a parent's voice, for example.
Richter believes these apps are an entirely new art form.
Mr. RICHTER: People ask are you creating books. Are you creating games? Are you creating, you know, animations? And the answer is yes. And that's what we set out to do - books you can play with and games you can read.
NEARY: But as you might expect, for some, an app will always be just an app.
Professor PHILIP NEL (Director, Program in Children's Literature, Kansas State University): It's not a book, for a number of reasons.
NEARY: Philip Nel is a professor of English and director of the Children's Literature program at Kansas State University.
Prof. NEL: One, is that in a traditional reading experience, the reader is in charge. The reader acts on the book. With the interactive e-book, the reader does still act on the book but the book also acts on - and depending on the adaptation, sometimes against the reader. So I would say that it's not a book; it's maybe a relative of the book, but it's not quite a book.
NEARY: Nel agrees with Richter that these apps are something entirely different. He says highlighting the words can be helpful to a young reader, but he thinks some of the sound effects and interactive features may interfere with the process of reading
Prof. NEL: Reading may be involved but there's more to it than that, and it's different than that. It's, you know, we don't read a film. We watch a film. We don't read a videogame. We play a videogame. And I was trying to think: What's the verb to describe what the enhanced e-book experience is like. Is it work? Is it use? Do we play an enhanced e-book?
NEARY: Its true that some of the bells and whistles in kids' book apps can be distracting, says Elizabeth Bird. She's a librarian at the New York Public Library, who's come up with some criteria for evaluating children's book apps. She says it's important that all the artwork and interactive features in an app are well-integrated with the story. Obviously not all apps are equal, says Bird, but the ones that get it right can take a book to a new level.
Ms. ELIZABETH BIRD (Senior Librarian, New York Public Library): They allow you to do things that you really couldn't do before. For example, there's a wonderful "Peter Rabbit" app that's out right now, which sort of turns "Peter Rabbit" into a virtual pop-up book. And you can go beyond that. I mean, there're apps where you can touch a word, it will pronounce it for you - but it could pronounce it for you in any language, so you could learn a language a second way by using one of these picture book apps.
NEARY: Bird doesn't believe apps are about to overtake books. She says kids move seamlessly back and forth between traditional print books and digital books all the time. And if a parent wants to use a book app to distract a child, well, Bird doesn't see a problem with that either.
Ms. BIRD: Let's say that I'm in a grocery store and I see a parent handing their phone to their child. Do I want them to hand the child a game like "Angry Birds?" Or do I want them to hand them "Freight Train" by Donald Crews in the app form. I would prefer that they hand them the book.
NEARY: Kids' book apps are so new, says Michel Kripalani, it's not surprising there are problems still to be resolved. But when he thinks about his daughter, those questions go away.
Mr. KRIPALANI: I just stand back in awe and I just say wow. She is just going to be able to absorb so much, so much faster, so much earlier. It's really, really awe-inspiring when you see a, you know, three or four-year-old child that really gets it.
NEARY: And of course, just like a good old fashioned book, an app works best when a parent and child enjoy it together.
Mr. KRIPALANI: Kentia, can you touch the puppy?
(Soundbite of an e-book)
Unidentified Woman #2: Pup.
(Soundbite of a barking dog)
Mr. KRIPALANI: Can you touch the cup?
Unidentified Woman #2: Cup.
Mr. KRIPALANI: Good job.
NEARY: Lynn Neary, NPR News, Washington.
MONTAGNE: And for links to download "A Present for Milo," "The Cat in the Hat" and the other apps we just heard about, visit NPR.org.
It's MORNING EDITION from NPR News. I'm Renee Montagne.
LINDA WERTHEIMER, host:
And I'm Linda Wertheimer.
Copyright © 2011 NPR. All rights reserved. Visit our website terms of use and permissions pages at www.npr.org for further information.
NPR transcripts are created on a rush deadline by Verb8tm, Inc., an NPR contractor, and produced using a proprietary transcription process developed with NPR. This text may not be in its final form and may be updated or revised in the future. Accuracy and availability may vary. The authoritative record of NPR's programming is the audio record.


text:
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text:
When you use the voice recognition software on your smartphone (like Siri on the iPhone) all of your voice commands are recorded and retained by the software manufacturer (like Apple, Samsung, or Google). You might already have known this, but what you probably didn't realize is those voice files aren't just sitting on servers somewhere in Silicon Valley; some of them are being listened to by total strangers on the internet. In fact, I listened to almost 200 of them today.
This week, a Reddit post picked up steam when a user wrote that she had started a new job at a company called Walk N'Talk Technologies—a company neither she nor I was able to verify online. Her job was to listen to voice recordings to see if they match up with text in order to evaluate the accuracy of a voice-to-text program.
"At first, I thought these sound bites were completely random. Then I began to notice a pattern. Soon, I realized that I was hearing people's commands given to their mobile devices," FallenMyst wrote.
FallenMyst later told me the work she was doing was through CrowdFlower, a crowdsourced data mining company that pays low wages for people to do easy, repetitive data analysis for various third-party companies.
I signed up for CrowdFlower myself and tracked down the post enlisting workers to analyze the voice-to-text examples, for one cent per 10 voice recordings they analyzed.
An example of some of the sound and text files.
While none of the clips had any specific identifying information, it seemed very likely they were obtained from individuals using their phone's voice recognition. The clips ranged from asking questions like "what time is it?" and "what's the weather like today?" to giving commands like "text Dakota: 'Sorry, I'm bored." There were also plenty of examples of the silly, joking-around babble that many people spew at their phones from "will you marry me?" to "show me some boobies."
While the project page did not say where the voice recordings came from, many clips I listened to were addressed to Galaxy phones:
"Galaxy, can you turn on the music?"
"Hi Galaxy, who sold more rock records than anybody else?"
"Galaxy, will you have sex with me?"
Samsung's terms of service state that the company may collect voice information "such as recordings of your voice that we make (and may store on our servers) when you use voice commands to control a service," and that Samsung works with a third-party speech-to-text conversion service that may receive and store this information. Though I didn't identify any Siri-specific voice clips, Apple has similar terms of service when it comes to collecting voice data, but it does not reference sending that data to a third party.
Apple spokesperson Trudy Muller told Wired that the company strips personal information from voice recordings before storing it for analysis it within Apple to improve the software. I reached out to both Apple and Samsung but did not hear back by the time this story was published. We will update this story if either company provides a response.
But while it may be within the legal limits of the companies to farm out these short, anonymous voice clips to strangers online, it's certainly not a well-known practice, explained Christopher Soghoian, the principal technologist at the American Civil Liberties Union.
"Many Americans would probably be shocked to learn that the contents of what they're saying is even being transmitted to Apple or Google or Samsung. I think many people probably think that Siri's only on their phone," Soghoian told me.
But Soghoian stopped short of calling it an invasion of privacy, telling me that the company's motivations seem to be to improve their voice recognition software, not to broadcast personal information about its customers. He added that if we want voice recognition software to get better, the companies creating it will need to collect data and, until the software improves, a human will have to listen to that data.
The problem arises when most people dictating at their phone don't realize that another person might someday listen to it, Soghoian said.
"Consumers have a certain expectation about what's happening when they interact with a company. People don't like it when they think they're talking to a computer and they're not or vice versa," Soghoian told me.
And as one of the people who did listen to these recordings, I can understand why. There was no personal information or any way to identify the voices in the brief, one-to-five-second snippets. But there's something about hearing a total stranger say "love you. Send." that feels transgressive.
"People text really sensitive things sometimes," Soghoian said.
"Just because the text message doesn't begin with 'my name is and my social security number is' doesn't mean there isn't going to be sensitive information in there."


text:
Bladder Cancer
Bladder cancer is a disease in which malignant cells arise in the bladder. Symptoms can include blood in the urine, pain during urination, increased frequency of passing urine, or feeling the need to urinate but with nothing coming out. The bulk of bladder cancers are histlogically classed as transitional cell carcinomas which arise in the uroepithelium (lining of the bladder). Other types include squamous cell carcinomas, and adenocarcinomas. Treatment will depend on how far the tumour has invaded the surrounding tissues, and if it has spread to other parts of the body. World-wide about 260,000 people are diagnosed with bladder cancer each year.
Information for Health Professionals / Researchers
Latest Research Publications
Molecular Biology of Bladder Cancer
Urinary System Cancers
Information Patients and the Public (16 links)
What You Need To Know About Bladder Cancer
National Cancer Institute
Detailed booklet about transitional cell cancer (TCC) of the bladder.
Cancer Research UK
CancerHelp information is examined by both expert and lay reviewers. Content is reviewed every 12 to 18 months. Further info.
Content is peer reviewed and Cancer.Net has an Editorial Board of experts and advocates. Content is reviewed annually or as needed. Further info.
Macmillan Cancer Support
Content is developed by a team of information development nurses and content editors, and reviewed by health professionals. Further info.
NHS Choices
NHS Choices information is quality assured by experts and content is reviewed at least every 2 years. Further info.
Cancer Research UK
CancerHelp information is examined by both expert and lay reviewers. Content is reviewed every 12 to 18 months. Further info.
Statistics for the UK, including incidence, mortality, survival, risk factors and stats related to treatment and symptom relief.
A charity which works with healthcare professionals, patients, their carers and the general public, to help improve the care of people with bladder cancer through awareness raising, education and research projects
Bladder Cancer
Mayo Clinic
Dr. Jeff Karnes describes symptoms of bladder cancer, diagnosis, and treatment options. Dr. Karnes also discusses risk factors for bladder cancer.
Founded in September 2009, Bladder Cancer Canada is a patient advocacy organization dedicated to bladder cancer issues. Bladder Cancer Canada is a Canadian registered charitable non-profit corporation.
Association for International Cancer Research
Patient produced site with information and support resources.
Discussion and support list for Bladder Cancer & Transitional Cell Carcinoma
Blæreforeningen | Danish Bladder Society - Dansk - English
An association of individuals with bladder cancer, bladder polyps / papillomas and their relatives.
David I. Quinn, MD: Bladder Cancer 101
American Society of Clinical Oncology
Dr. David Quinn, a bladder cancer expert, gives us an educational overview of bladder cancer. Risk factors, signs and symptoms and diagnosis. This 8 minute video interview was filmed at the American Society of Clinical Oncology Annual Meeting in Chicago 2012.
Information for Health Professionals / Researchers (8 links)
- PubMed search for publications about Bladder Cancer - Limit search to: [Reviews]
PubMed Central search for free-access publications about Bladder Cancer
MeSH term: Urinary Bladder Neoplasms
US National Library of Medicine
PubMed has over 22 million citations for biomedical literature from MEDLINE, life science journals, and online books. Constantly updated.
National Cancer Institute
PDQ summaries are written and frequently updated by editorial boards of experts Further info.
Cancer Research UK
CancerHelp information is examined by both expert and lay reviewers. Content is reviewed every 12 to 18 months. Further info.
Statistics for the UK, including incidence, mortality, survival, risk factors and stats related to treatment and symptom relief.
NHS Evidence
Regularly updated and reviewed. Further info.
Detailed reference article covering etiology, histology, staging, metastatic patterns, symptoms, differential diagnoses, prognosis, treatment and follow-up.
Patient UK
Clinical Trials - Bladder Cancer
National Cancer Institute
Search of the NCI's database of 12,000+ clinical trials from around the world.
SEER Stat Fact Sheets: Bladder
SEER, National Cancer Institute
Overview and specific fact sheets on incidence and mortality, survival and stage, lifetime risk, and prevalence.
Latest Research Publications
This list of publications is regularly updated (Source: PubMed).
Laparoscopic Radical Cystoprostatectomy, Surgical Technique and Result: A Case Report.
J Med Assoc Thai. 2015; 98 Suppl 10:S154-7 [PubMed] Related Publications
MATERIAL AND METHOD: A 72-year-old Thai male presented with gross hematuria. Cystoscope was performed. Large bladder tumor near right ureteric orifice was observed. Then, transurethral resection of bladder tumor was performed. His tumor pathology was muscle invasive high grade urothelial carcinoma with clinical staging T2N0M0. Laparoscopic radical cystoprostatectomy was then conducted with bilateral pelvic nodes dissection and ileal conduit.
RESULTS: Operation period was eight hours. Blood loss was 500 ml. In pathological results, tumor invaded bladder muscle into perivesical tissue. Tumor margin was free. Lymph nodes were positive for malignancy 5/7 for right side and 0/4 for left side. Pathological staging was T3aN1M0. After post-operative period, the patient was discharged from hospital uneventfully.
CONCLUSION: Laparoscopic radical cystoprostatectomy in Maha Chakri Sirindhorn Medical Center is minimal invasive, feasible and safe. However, a longer follow-up period regarding long-term cancer control as well as functional and technical aspects will be required.
Improved Noninvasive Bladder Cancer Diagnosis using Urine Sediments and Novel DNA Methylation Biomarker Panels.
Clin Lab. 2016; 62(3):327-36 [PubMed] Related Publications
METHODS: Seven candidate genes with known cancer associations were selected for this study. The DNA methylation status of the candidate genes was analyzed by methylation-specific polymerase chain reaction assays to evaluate the relationship between bladder cancer and target gene methylation status in the urine sediments of participants.
RESULTS: 112 bladder cancer patients, 10 healthy volunteers, and 17 glandular cystitis patients were enrolled. There were significant differences in the methylation status of p14ARF, RUNX3, RARβ, DAPK, and HPP1 between the healthy control, glandular cystitis, and bladder cancer groups (p = 0.027, p < 0.001, p < 0.001, p = 0.030 and p = 0.003, respectively). A panel composed of all five genes with significant methylation differences yielded an area under the receiver-operating characteristic curve (AUC) of 0.936 and had 98.21% sensitivity and 88.89% specificity, while a panel using just two of these genes (RUNX3 and RARP) yielded an AUC of 0.918 with 96.64% sensitivity and 88.89% specificity. Another panel of two genes (p14ARF and HPP1) had 100% specificity, but an AUC of 0.688 and 37.50% sensitivity.
CONCLUSIONS: Using the urine of bladder cancer patients and healthy controls, we assessed several novel DNA methylation biomarker panels that demonstrated good bladder cancer detection capability. Based on the results of this study we recommend the RUNX3 and RARβ panel as the first choice for bladder cancer detection. In suspicious or difficult to diagnose cases, the p14ARF and HPP1 panel could be used as an additional diagnostic tool due to its high specificity.
Thyroid metastasis of bladder transitional cell carcinoma.
Malays J Pathol. 2016; 38(1):65-70 [PubMed] Related Publications
Spinal tuberculosis with severe neurological symptoms as a complication of intravesical BCG therapy for carcinoma of the bladder.
Neurol Neurochir Pol. 2016; 50(2):131-8 [PubMed] Related Publications
MATERIAL AND METHODS: In the first patient, aged 66, after intravesical BCG therapy for bladder carcinoma, back pain and spastic paralysis of the lower limbs were observed. The MRI and CT revealed destruction of the intervertebral disc and vertebral endplates Th11-Th12. Mycobacterium tuberculosis complex bacilli were cultured from the material obtained by puncture aspiration. In the second patient, aged 35 years, during intravesical BCG immunotherapy for carcinoma of the bladder, girdle thoracic spine pain was observed. The MRI and CT of the spine showed visible lesions characteristic of tuberculosis. Immobilization in a plaster corset and implementation of antituberculous treatment resulted in quick relief of the pain and healing of the tuberculosis focus in the spine.
CONCLUSION: The cases described in the work are the first documented reports in the Polish literature of spinal tuberculosis which occurred as a complication of intravesical administration of bacilli Calmette-Guérin. The diagnosis was based on the finding of BCG vaccine bacillus with molecular methods or PCR. Full antimycobacterial treatment was implemented.
Rosiglitazone Use and the Risk of Bladder Cancer in Patients With Type 2 Diabetes.
Medicine (Baltimore). 2016; 95(6):e2786 [PubMed] Free Access to Full Article Related Publications
Arteriovenous Malformation Masquerading as a Bladder Tumor. A Case Report.
Anal Quant Cytopathol Histpathol. 2015; 37(5):322-5 [PubMed] Related Publications
CASE REPORT: A 47-year-old man presented with irritative symptoms and hematuria. Cystoscopically the lesion appeared as an erythematous, broad-based mass obscuring the right ureteral orifice. The patient underwent cystoprostatectomy for suspected mass lesion. Histologically the bladder tumor was composed of numerous malformed blood vessels of various calibers with myxoid degeneration. Immunohistochemically the bland endothelial cells lining in the vessels were reactive for markers of CD31 and CD34. Ki67 index was < 1%. The patient was free of disease 24 months after surgery.
CONCLUSION: Our findings broaden the morphologic spectrum of bladder arteriovenous malformation and emphasize its deceptive presentation.
Bladder cancer risk from the perspective of genetic polymorphisms in the carcinogen metabolizing enzymes.
J BUON. 2015 Nov-Dec; 20(6):1397-406 [PubMed] Related Publications
Copper Transporter-CTR1 Expression and Pathological Outcomes in Platinum-treated Muscle-invasive Bladder Cancer Patients.
Anticancer Res. 2016; 36(2):495-501 [PubMed] Related Publications
PATIENTS AND METHODS: We identified matched paraffin-embedded tissues from pre-NAC transurethral bladder tumor resection (TURBT) and post-NAC radical cystectomy (RC) specimens in 47 patients with MIBC who received Pt-based NAC. Tumor and adjacent normal tissues were stained with CTR1 antibody. CTR1 expression was determined through immunohistochemistry by two pathologists blinded to the outcome (0=undetectable; 1+=barely detectable; 2+=moderate; and 3+=intense staining). Pathological response was defined as either down-staging to non-MIBC (≤pT1N0M0) or complete pathological response (pT0). Pathological outcome was compared between the CTR1 expression groups.
RESULTS: Forty-three percent of TURBT and 41% of RC specimens expressed a CTR1 score of 3+. Forty-four percent of patients had a pathological response to NAC, and 17% had pT0 disease at cystectomy. In both pre-NAC TURBT and post-NAC RC specimens, a CTR1 expression score of 3+ correlated with pathological response (p=0.0076 and p=0.023, respectively).
CONCLUSION: This is the first study to demonstrate a correlation between CTR1 tumor expression and pathological outcome in Pt-treated MIBC. These findings suggest that CTR1 expression may be a biomarker for Pt sensitivity.
Risk Factors Predictive of Recurrence and Progression for Patients Who Suffered Initial Recurrence After Transurethral Resection of Stage pT1 Bladder Tumor in Chinese Population: A Retrospective Study.
Medicine (Baltimore). 2016; 95(5):e2625 [PubMed] Free Access to Full Article Related Publications
Complete Response and Fatigue Improvement With the Combined Use of Cyclophosphamide and Quercetin in a Patient With Metastatic Bladder Cancer: A Case Report.
Medicine (Baltimore). 2016; 95(5):e2598 [PubMed] Free Access to Full Article Related Publications
Improving Access to Adjuvant Intravesical Therapy for Non-Muscle Invasive Bladder Cancer in a Community Hospital.
Urol Nurs. 2015 Nov-Dec; 35(6):287-91 [PubMed] Related Publications
Combination of Intravesical Chemotherapy and Bacillus Calmette-Guerin Versus Bacillus Calmette-Guerin Monotherapy in Intermediate- and High-risk Nonmuscle Invasive Bladder Cancer: A Systematic Review and Meta-analysis.
Medicine (Baltimore). 2016; 95(3):e2572 [PubMed] Related Publications
Metabolic alterations in bladder cancer: applications for cancer imaging.
Exp Cell Res. 2016; 341(1):77-83 [PubMed] Related Publications
KLF5 promotes cell migration by up-regulating FYN in bladder cancer cells.
FEBS Lett. 2016; 590(3):408-18 [PubMed] Related Publications
miR-1182 inhibits growth and mediates the chemosensitivity of bladder cancer by targeting hTERT.
Biochem Biophys Res Commun. 2016; 470(2):445-52 [PubMed] Related Publications
Gene expression test for the non-invasive diagnosis of bladder cancer: A prospective, blinded, international and multicenter validation study.
Eur J Cancer. 2016; 54:131-8 [PubMed] Related Publications
METHODS: Consecutive voided urine samples from BC patients and controls were prospectively collected in five European centres (n=789). Finally, 525 samples were successfully analysed. Gene expression values were quantified using TaqMan Arrays and previously reported diagnostic algorithms were applied to gene expression data. Results from the most accurate gene signature for BC diagnosis were associated with clinical parameters using analysis of variance test.
RESULTS: High diagnostic accuracy for the four gene signatures was found in the independent validation set (area under curve [AUC]=0.903-0.918), with the signature composed of two genes (GS_D2) having the best performance (sensitivity: 81.48%; specificity: 91.26%; AUC: 0.918). The diagnostic accuracy of GS_D2 was not affected by the number of tumours (p=0.58) but was statistically associated with tumour size (p=0.008). Also, GS_D2 diagnostic accuracy increases with increasing BC tumour risk. We found no differences in the performance of the GS_D2 test among the populations and centres in detecting tumours (p=0.7) and controls (p=0.2).
CONCLUSIONS: Our GS_D2 test is non-invasive, non-observer dependent and non-labour-intensive, and has demonstrated diagnostic accuracy in an independent, international and multicenter study, equal or superior to the current gold standard (cystoscopy combined with cytology). Additionally, it has higher sensitivity than cytology while maintaining its specificity. Consequently, it meets the requirements for consideration as a molecular test applicable to clinical practice in the management of BC.
Poly(I:C) potentiates Bacillus Calmette-Guérin immunotherapy for bladder cancer.
Cancer Immunol Immunother. 2016; 65(2):223-34 [PubMed] Related Publications
Prognostic Genetic Signatures in Upper Tract Urothelial Carcinoma.
Curr Urol Rep. 2016; 17(2):12 [PubMed] Free Access to Full Article Related Publications
Role of Sonic Hedgehog (Shh) Signaling in Bladder Cancer Stemness and Tumorigenesis.
Curr Urol Rep. 2016; 17(2):11 [PubMed] Related Publications
Rationale and Early Experience with Prophylactic Placement of Mesh to Prevent Parastomal Hernia Formation after Ileal Conduit Urinary Diversion and Cystectomy for Bladder Cancer.
Curr Urol Rep. 2016; 17(2):9 [PubMed] Free Access to Full Article Related Publications
Stapled orthotopic ileal neobladder after radical cystectomy for bladder cancer: Functional results and complications over a 20-year period.
Eur J Surg Oncol. 2016; 42(3):412-8 [PubMed] Related Publications
MATERIALS AND METHODS: From 1992 to 2012 we performed 606 radical cystectomies with stapled orthotopic neobladder substitution in male patients. The median patient age was 65 years (interquartile range [IQR]: 58-71).
RESULTS: Median operative time was 205 min (IQR: 180-225). The overall survival rates at 5, 10, 15, and 20 yr were 68% (336 of 494), 55% (207 of 376), 38% (98 of 259), and 23% (14 of 62), respectively, and the disease specific survival rates were 75% (371 of 494), 59% (222 of 376), 50% (130 of 259), and 35% (22 of 62), respectively. After a median follow-up of 81 months (IQR: 30-144), a total of 147 early (less than 90 days) complications (38 diversion related, 109 diversion unrelated) occurred in 144 patients (24%); 163 late complications (141 diversion related, 22 diversion unrelated) affected 141 patients (23%). At 60 months, daytime and nighttime continence was complete in 96% and 72% of cases, respectively. Urodynamic studies showed that maximum capacity, residual volume, maximum flow rate, pressure at maximum capacity, and maximum outlet closure pressure were not statistically different at 12 and 60 months postoperatively.
CONCLUSIONS: The use of a stapler when performing orthotopic neobladders significantly reduces the operating time, and offers good functional results with acceptable complication rates. Our results could encourage the use of a stapler when performing an ileal neobladder during laparoscopic and robotic radical cystectomies.
Clinical significance of serum and urinary HER2/neu protein levels in primary non-muscle invasive bladder cancer.
Int Braz J Urol. 2015 Nov-Dec; 41(6):1080-7 [PubMed] Free Access to Full Article Related Publications
MATERIALS AND METHODS: Fourty-four patients with primary non-muscle invasive bladder tumors (Group 2) and 40 healthy control group (Group 1) were included the study. Blood and urinary samples were collected from all patients and HER2/neu levels were measured by ELISA method. Blood and urinary HER2/neu levels and additionally, ratio of urinary HER2/neu levels to urinary creatinine levels were recorded. Demographic data and tumor characteristics were recorded.
RESULTS: Mean serum HER2/neu levels were similar between two groups and statistically significant difference wasn't observed. Urinary HER2/neu levels were significantly higher in group 2 than group 1. Ratio of urinary HER2/neu to urinary creatinine was significantly higher in group 2 than group 1, (p=0,021). Serum and urinary HER2/ neu levels were not associated with tumor stage, grade, recurrence and progression while ratio of urinary HER2/neu to urinary creatinin levels were significantly higher in high-grade tumors. HER2/neu, the sensitivity of the test was found to be 20.5%, and the specificity was 97.5%, also for the urinary HER2/neu/urinary creatinine ratio, the sensitivity and specificity of the test were found to be 31.8% and 87.5%, respectively.
CONCLUSIONS: Urinary HER2/neu and ratio of urinary creatinine urine were significantly higher in patients with bladder cancer compared to healthy subjects. Large series and controlled studies are needed for use as a tumor marker.
Regulator of cullins-1 expression knockdown suppresses the malignant progression of muscle-invasive transitional cell carcinoma by regulating mTOR/DEPTOR pathway.
Br J Cancer. 2016; 114(3):305-13 [PubMed] Article available free on PMC after 02/02/2017 Related Publications
METHODS: ROC1 expression in cancer cells was knocked down by siRNA silencing. The effects of ROC1 silencing were evaluated by in vitro assays for cell migration and by an in vivo mouse metastasis model. Epithelial-mesenchymal transition (EMT) induction was evaluated by immunofluorescence staining and western blotting of EMT-associated proteins. ROC1 expression in human tumours was further evaluated by immunohistochemical analysis.
RESULTS: ROC1 knockdown suppresses bladder cancer cell migration by inhibiting EMT. ROC1 knockdown inhibited EMT by inhibiting mammalian target of rapamycin (mTOR) activity via the accumulation of the mTOR-inhibitory protein DEPTOR, a CRL substrate. DEPTOR knockdown partially rescued ROC1 knockdown-inhibited EMT and the ROC1-induced inhibition of cancer cell migration. Furthermore, in vivo studies using a nude mouse metastasis model confirmed the in vitro data. Finally, tissue microarray analysis of clinical bladder cancer specimens indicated a positive correlation between ROC1 expression and EMT.
CONCLUSIONS: ROC1 has an important role in the malignant progression of bladder cancer via the mTOR/DEPTOR pathway. ROC1 may serve as a novel therapeutic target for the treatment of muscle-invasive transitional cell carcinoma.
Standard or accelerated methotrexate, vinblastine, doxorubicin and cisplatin as neoadjuvant chemotherapy for locally advanced urothelial bladder cancer: Does dose intensity matter?
Eur J Cancer. 2016; 54:69-74 [PubMed] Related Publications
PATIENTS AND METHODS: We performed a retrospective analysis of 241 consecutive bladder cancer patients who received a combination of methotrexate, vinblastine, doxorubicin and cisplatin (MVAC) using a standard (52 patients) or an accelerated schedule (189 patients) as NAC before radical cystectomy in 17 centres of the French GEnito-urinary TUmour Group from March 2004-May 2013.
RESULTS: The median age was 62 years. As expected, the median number of cycles, the median total dose of cisplatin and the median cisplatin dose intensity were higher in patients treated with the accelerated regimen. Conversely, the median duration of chemotherapy was shorter. Regarding toxicity, grade III/IV neutropenia, grade III thrombocytopenia and grade III anaemia as well were more frequently observed in patients treated with the standard regimen. Among 211 (88%) patients who proceeded to cystectomy, 75 (35%) patients achieved an ypT0 pN0 status (no pathologic residual tumour cells) with no significant difference according to the MVAC schedule. Three-year overall survival rates were 66.5% (95% confidence interval [CI], 56-79) and 72% (95% CI, 59.5-88) in the standard and accelerated cohorts, respectively. In the multivariate analysis, two independent prognostic parameters were retained: the ypT0 stage and the ypN0 stage. Heterogeneity test did not show any interaction with NAC regimens.
CONCLUSION: Similar pathological response and survival rates were observed whatever the chemotherapy regimen used. Haematological toxicity was greater in patients who received standard MVAC.
MicroRNA-542-3p suppresses cellular proliferation of bladder cancer cells through post-transcriptionally regulating survivin.
Gene. 2016; 579(2):146-52 [PubMed] Related Publications
METHODS: Expression levels of miR-542-3p and survivin mRNA in bladder cancer and adjacent normal tissues were detected by quantitative RT-PCR. Cell proliferation and cell cycle were assessed by cell viability assay, flow cytometry and colony formation assay based on two human bladder cancer cell lines.
RESULTS: MiR-542-3p expression was downregulated, while survivin mRNA expression was upregulated in bladder cancer tissues, compared to adjacent normal tissues (both P<0.001). Importantly, the expression level of miR-542-3p in bladder cancer tissues was negatively correlated with that of survivin mRNA. MiR-542-3p-low and/or survivin-high expression were all significantly associated with tumor stage (all P<0.05) and tumor recurrence (all P<0.05) of patients with bladder cancer. Moreover, the enforced expression of miR-542-3p remarkably inhibited cell proliferation by inducing G1 phase arrest in both T24 and J82 cells, and decreased the expression level of survivin protein. In contrast, the knock-down of miR-542-3p dramatically promoted the proliferation of bladder cancer cells by accelerating the progression of cell cycle and increased the expression level of survivin protein.
CONCLUSION: MiR-542-3p and its target gene survivin may play crucial roles in the aggressive progression of human bladder cancer. More interestingly, miR-542-3p may function as a tumor suppressor and inhibit the proliferation of bladder cancer cells, implying that miR-542-3p-survivin signal axis might be a novel therapeutic target of this disease.
LDH-A promotes malignant progression via activation of epithelial-to-mesenchymal transition and conferring stemness in muscle-invasive bladder cancer.
Biochem Biophys Res Commun. 2016; 469(4):985-92 [PubMed] Related Publications
Villous Adenoma of the Urinary Bladder: A Brief Review of the Literature.
Arch Pathol Lab Med. 2016; 140(1):91-3 [PubMed] Related Publications
Perioperative treatment and radical cystectomy for bladder cancer--a population based trend analysis of 10,338 patients in the Netherlands.
Eur J Cancer. 2016; 54:18-26 [PubMed] Related Publications
METHODS: This nationwide, retrospective, population-based study included cTa/is, T1-4, N0-3, M0-1 bladder cancer patients from the Netherlands Cancer Registry who underwent RC with curative intent between 1995 and 2013. PT-administration over time was compared with chi-square tests. Multivariable logistic regression analyses were performed to identify characteristics associated with PT usage. The sub-groups cT2-4N0M0 and cT2-4, N0 or NX, M0 or MX were separately analysed.
RESULTS: In total, 10,338 patients met inclusion criteria. Eighty-six percent did not receive PT, 7.0% received NAC (or induction chemotherapy [IC]), 3.2% NAR, 1.8% AC, and 2.1% AR. NAC usage increased from 0.6% in 1995 to 21% in 2013 (p < 0.001), application of NAR decreased from 15% to 0.4% (p < 0.001). Usage of AC and AR in 2013 was <1.5%. Comparable temporal trends were found in 6032 patients staged cT2-4N0M0. Multivariable logistic regression analysis revealed that younger age, ≥ cT3, ≥ cN1 and treatment in academic/teaching hospitals were associated with NAC or IC (all p < 0.05).
CONCLUSIONS: The increase in NAC administration in the Netherlands reflects a slow but steady adoption of evidence-based guidelines over the last two decades. Considerable variability in patients' and hospital characteristics in the likelihood of receiving NAC exists. Conversely, NAR, AR and AC are hardly administered anymore.
Long-Term Outcomes Among Patients Who Achieve Complete or Near-Complete Responses After the Induction Phase of Bladder-Preserving Combined-Modality Therapy for Muscle-Invasive Bladder Cancer: A Pooled Analysis of NRG Oncology/RTOG 9906 and 0233.
Int J Radiat Oncol Biol Phys. 2016; 94(1):67-74 [PubMed] Article available free on PMC after 01/01/2017 Related Publications
PATIENTS AND METHODS: A pooled analysis was performed on 119 eligible patients with muscle-invasive bladder cancer enrolled on NRG Oncology Radiation Therapy Oncology Group trials 9906 and 0233, who were classified as having a complete (T0) or near-complete (Ta or Tis) response after induction chemo-RT and completed consolidation with a total RT dose of at least 60 Gy. Bladder recurrence, salvage cystectomy rates, and disease-specific survival were estimated by the cumulative incidence method and bladder-intact and overall survivals by the Kaplan-Meier method.
RESULTS: Among the 119 eligible patients, 101 (85%) achieved T0, and 18 (15%) achieved Ta or Tis after induction chemo-RT and proceeded to consolidation. After a median follow-up of 5.9 years, 36 of 101 T0 patients (36%) versus 5 of 18 Ta or Tis patients (28%) experienced bladder recurrence (P=.52). Thirteen patients among complete responders eventually required late salvage cystectomy for tumor recurrence, compared with 1 patient among near-complete responders (P=.63). Disease-specific, bladder-intact, and overall survivals were not significantly different between T0 and Ta/Tis cases.
CONCLUSIONS: The bladder recurrence and salvage cystectomy rates of the complete and the near-complete responders were similar. Therefore it is reasonable to recommend that patients with Ta or Tis after induction chemo-RT continue with bladder-sparing therapy with consolidation chemo-RT to full dose (60-64 Gy).
Predictors of costs associated with radical cystectomy for bladder cancer: A population-based retrospective cohort study in the province of Quebec, Canada.
J Surg Oncol. 2016; 113(2):223-8 [PubMed] Related Publications
METHODS: We conducted a retrospective analysis in a cohort of 2,759 patients who underwent RC for BC between 2000 and 2009. We analyzed predictors of pre-surgery, RC, post-surgery, and total costs. The following variables were considered as potential predictors: age, gender, hospital/surgeon case load, academic hospital, and geo-administrative region. Multivariate linear regression was used to determine predictors.
RESULTS: Predictors of pre-surgery costs were: age (β = 808.64, P < 0.0001) and having surgery in an academic hospital (β = 511.42, P = 0.003). Increased RC costs were associated with age (β = 196.73, P = 0.0006), hospital/surgeon annual load (β = 484.45 and β = 254.21, P < 0.0001, respectively). Having surgery in academic hospitals and geographic region were significant predictors of low RC costs (β = -1085.82 and β = -449.31, P < 0.0001, respectively). Increasing age and the presence of post-operative complications were predictors of high post-operative costs (β = 623.48, β = 5781.44, P = 0.01, respectively), while hospital load was associated with low post-surgery costs (β = -949.79, P < 0.0001).
CONCLUSION: Patients' age and surgery performed by high-volume health providers were predictive factors of high RC costs. Low RC costs were associated with surgeries performed in academic hospitals.


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Graphics for posters
The theme that I was required for this poster were superheroes, I was inspired by a generic style of super hero. The proportions are very particular (720x2016), so I had difficulty inserting the character into a so close settlement. Poster lettering must be placed in space at the top and if desired, on the metal plate at the bottom of the spacecraft.
Close Up


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Received from local host 127.0.0.1 ???????
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Sleuthkit is a collection of open source forensic tools. Did you at any time download those or subscribe to their mailing lists?
Old Nabble - The Sleuth Kit forum
The Sleuth Kit | Download The Sleuth Kit software for free at SourceForge.net
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Compact Monitors Stage 1.2
Enter the Stage! Dual driver system (balanced armature) Upgrade possible at any time Stage 1.2 is available in two different versions (transparent and beige)
Compact Monitors Stage 2
Top class dual driver InEar with exceptional dynamic and sound. Two drivers (one for the low/mid frequencies and one for the high frequencies) in each earpiece will give you an extraordinary performance with crystal clear high frequencies combined with tight and precise bass Due to the specially selected drivers this InEar creates a headroom at the low end that usually would not be...
Compact Monitors Stage 3
Studio sound meets In Ear - ...enter the next Stage! Extremely precise and linear sound - three drivers and a crossover with parts of absolutely close tolerance makes the Stage 3 sound perfectly balanced No matter where – stage, studio or for your portable player: Stage 3 will make you get addicted to sound...!
Compact Monitors Stage 4
Cable: replaceable due to miniature plugs (gold plated) Lenght: 1.38 m Shell: acrylic Technology: Three-Way-System with four drivers Sensitivity: 120dB SPL at 1mW Frequency: 10 Hz - 19 kHz Impedance: 20 Ohm ______________________________________________________________________________________________________________ Four balanced armature drivers and a complex crossover create lowest bass,...
ZERO AUDIO-ear stereo headphone carbo Tenore ZH-DX200-CT
"Let me preface this review by first letting you understand where I come from as I think that will give you some valuable perspective of my thoughts and opinions about this little gem. This also probably won't be a conventional review in that I describe in detail about the sound signature but I will make clear and efficient comparisons to well known IEMs. So I am a music producer and..." --Marc Lian
Zero Audio ZH-BX300
Zero Audio ZH-BX300
Zero Audio ZH-BX500
"A mids-focused specialist with a little bass thump and smooth, relaxed treble (recessed, but still has some detail). Not an especially engaging sound (a little too relaxed maybe). Decent across genres, but tend to congestion during busy/noisy passages. I find them particularly useful for low volume podcast legibility, though with podcasts that are poorly leveled, subject to intrusive volume..." --Raketen


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Chapel Cross Guest House
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TripAdvisor Reviews Chapel Cross Guest House Roslin
Travel Blogs from Roslin
Roslin - The Last Day of Spring
... steps to lovers' nooks A secret kiss to steal Flowing 'round the castle Over boulders, rocks and stones Swirls the North Esk River swiftly Dancing deep red undertones With paths in all directions You'll be lost and lead astray The perfect place to find yourself Upon a sunny day Forget-me-nots and buttercups Daisies and bluebells If fairies were to truly live Then this is where they'd ...
Day 12: Edinburgh
... which was kind of sad. They still have real government events at these places, and today was one of those days. A few guys in kilts were guarding the entrance. So we headed up to the other end of the royal mile in search of the castle.
As we approached the St. Giles Cathedral, we saw a guy with a guitar and some people starting to gather and thought nothing of it really. Then he started to sing. ...
I had a great flight from Singapore to London, as for some unknown but lovely reason just before I got on the plane they swapped my boarding pass for another with an upgrade to business. So I had a flat bed, and thus slept for 8 hours. Rather slow processing of non UK people at Heathrow, so I did not go to the lounge there. Arrived at Edinburgh a bit late, it is very green flying in. My little flat is tiny but adequate ...
Rosslyn Chapel
... inside, but click here if you would like to see some professional images :)
It was built and served as a Catholic Church until the Protestant Reformation outlawed Catholic worship. Like so many historic structures, it eventually suffered from disuse and neglect. When Queen Victoria stopped to visit, she declared that it was too beautiful to lose and restoration began. Rosslyn Chapel is made ...
I Don't Feel Like Dancing....
... if you wanted to go to Aberdeen by any chance...), to drop my stuff off. Went to the beach for ice cream. Was an absolutely lovely day, and I was able to call home and speak to my parents so that was awesome as well <3 Today I left my bag at the apartment office, and did some shopping, watched man of steel (terrible) and caught my train to Edinburgh. Arrived at my hostel shortly after 10, just staying in tonight, but i'm excited to explore! Peace and love Kimber ...


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Hot From the Oven
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- Happy New Year from Brian & Margot!
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Tag Archives: Pittsburgh
Pittsburgh Turkey Devonshire for Sandwich Day 2016!
Hello! Happy Sandwich Day! I honor of the occasion, I am sharing a post that first appeared in 2014. This post will be very relevant come the end of the month because it is a most excellent way to use up … Continue reading
Posted in cookbooks, Food, Recipes, Retro Food, Retro Recipes, Turkey Tagged bacon, cream sauce, Pittsburgh, sandwich, turkey 4 Comments
Christmas Parade Party Buffet!
A Christmas post, kittens! This year I had a party for the Christmas parade because it goes through my neighborhood. ALL THREE HOURS OF IT. I shit you not. It was like the Macy's Day parade. But with meth addicts and … Continue reading
Posted in 1970s, Beverages & Cocktails, cookbooks, Food, Recipes, Retro Food, Retro Recipes Tagged 1970s, cheese, Christmas, cocktail party, dip, holiday food, Hors d' oeuvres, Liberace, Liberace Cooks, Mayonnaise, Pittsburgh, punch, Scandanavian food, vintage cocktails 7 Comments
24-Hour Salad
I plucked a grey hair out of my left eyebrow this morning. This surprised me; although it should not, considering that for over five years, I dye my hair, not for fun, but out of necessity (I am sitting with light … Continue reading
Posted in cookbooks, Food, Fruit, Recipes, Retro Food, Retro Recipes, Salad Tagged custard, Judy Garland, mandarin oranges, Marshmallows, Pittsburgh, salad 8 Comments
Mike Kalina's Pittsburgh Potato Cheese Pierogies
PIEROGIES! One of my most favorite foods. Growing up in Pittsburgh, pierogies were everywhere. Everywhere! The best are the ones made by church ladies, and my Aunt Bonnie (goddamnit, why do I not write down the dough recipe when I … Continue reading
Posted in cookbooks, Food, International Cuisine, Retro Food, Retro Recipes Tagged onions, pierogi, pierogie, Pittsburgh, Polish food, Ukranian food 9 Comments
The Astronaut Wives Club Ham Loaf
On last night's premiere episode of The Astronaut Wives Club, Mrs. Alan Shepard gets all down in the doldrums either because her husband is in space or because he bangs anything in a bikini down at Cape Canaveral. Regardless, as she's … Continue reading
Posted in cookbooks, Food, Pork, Recipes, Retro Food, Retro Recipes Tagged Astronaut Wives Club, Ham, loaf, Pittsburgh, pork, television 1 Comment
Yinzerella's Lazy Pierogie Casserole
It's going to snow here today. I don't know how much, but snow is in the forecast. And when snow is in the forecast, there is nothing better to eat than a big, stick-to-your ribs, comfort food casserole. And when … Continue reading
Posted in Food, Recipes Tagged bacon, casserole, cheese, cottage cheese, mashed potatoes, New England Patriots, pasta, pee wee herman, pierogi, pierogie, Pittsburgh, Polish food, sauerkraut, Steelers 13 Comments
New Year Pretzel & City Chicken (A Very Pittsburgh New Year)
Happy New Year, kittens! The days of December 31 and January 1 are rife with superstition and things to do and not do in order to roll into the new year as a lucky duck and leave the bad parts … Continue reading
Posted in 1970s, Dessert, Food, Pork, Recipes, Retro Food, Retro Recipes Tagged Baking, Ben Wyatt, Brian, City Chicken, dessert, electric skillet, Giant Eagle, holiday food, new years, Pittsburgh, pork, pork and sauerkraut, pretzels, sauerkraut 7 Comments
Pittsburgh Turkey Devonshire Sandwich
Got turkey? I got a great way for you to use up some of your Thanksgiving leftovers. That is, if you like bacon and cheese sauce. And who doesn't (aside from our kosher and lactose intolerant friends)? When "sandwich" and … Continue reading
Posted in Food, Leftovers, Recipes, Retro Food, Retro Recipes, Turkey Tagged 1980s, bacon, cheddar, cheese, cream sauce, leftovers, Pittsburgh, sandwich, sandwiches, sauce, Thanksgiving, turkey 4 Comments
For National Sandwich Day: Isaly's Chipped Ham Barbecue
Yesterday was National Sandwich Day, which, should be celebrated nationally. It would have absolutely thrilled me to observe the day with a McRib, but, alas, the damn things never made it anywhere near Baltimore. So, I made a barbecue sandwich … Continue reading
Posted in Food, Recipes, Retro Food, Retro Recipes Tagged barbecue, Brian, cat, cat circle, Ham, isaly's, ketchup, McRib, Pittsburgh, sandwich, sandwiches, Tom Selleck Leave a comment
Yinz Sound Like Jagoffs
It's official. Yinzer, a.k.a. the official language of Pittsburgh, has been voted the WORST ACCENT IN AMERICA! I am oddly proud. Here is a fabulous example of the horrendous accent: As is this: I chose this Pittsburgh Dad one because … Continue reading
Posted in Etc., humor Tagged Pittsburgh Leave a comment


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04/09/14 – Today is National Antique Appreciation Day so of course Huggy Lowdown wanted to give a tribute to a fellow comedian. Bet you can't guess who! Also, according to Kanye, he wants to dip Kim K's hind parts in gold and you KNOW Huggy has a bit of advice for him!
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This Week's Celebrity Instagrams (1/7-1/13)
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PUT ME IN COACH: Creme De La Creme
As we get set for the Final Four games to tip off a little after 5 p.m. today, the main thing I noticed is that, even after the upsets, the wild finishes and the drama, the cream has risen to the top.
Whether by name recognition (Kentucky and UConn) or by seeding (Wisconsin) and Florida (which could easily fit into both categories based on its 21st century hardcourt success), the best teams have arrived at one of the grandest sports stages in Arlington Texas.
Though Kentucky entered the tournament as a No. 8 seed, the Wildcats have the strongest hoops tradition of the Final Four teams, maybe combined. You are probably familiar with some of the accolades, but let's go over it again.
The Wildcats are the winningiest program in college basketball history (76.1 percent) and have the most NCAA tournament appearances with 53 overall and wins with 117.
If a man named John Wooden (who was a snowstorm away from becoming the Gophers men's basketball coach), hadn't stopped by UCLA, the Wildcats eight NCAA basketball championships might be the most all time, as well.
For the record, UCLA has 11 championship trophies.
The Bruins are third All-Time in appearances in the event taking place this weekend with 16 Final Four appearances.
UConn also has a rich basketball tradition, which is also only slightly disguised by its No. 7 seed. The Huskies have taken home three NCAA championships, which is tied for sixth on the all-time list and have been to five Final Fours, which is ninth on the all-time list, along with 32 NCAA tournament appearances.
UConn is guided by one of the up-and-coming coaches in the nation in former NBA player Kevin Ollie, who has taken the Huskies to a Final Four in just his second year at the helm. He took over for Jim Calhoun, who decided to retire after the 2012 season.
The Gators' successful basketball roots don't run as deep, but they are a name you definitely recognize. Coach Billy Donovan and Florida splashed onto the scene ever since the millennium turned. The Gators have won three national championships in the past 15 years, including back-to-back titles in 2006 and 2007.
Donovan, alone, has become the winningest coach in Florida history with those back-to-back titles as well as three Final Four appearances, 12 NCAA tournament appearances and 15 consecutive postseason appearances.
His 28-10 mark in the NCAA tournament puts him third all-time with the likes of Duke coach Mike Krzyzewski and North Carolina coach Roy Williams – not a bad group to share a table with.
Of the four, the Badgers would be considered the new kids on the block and have ushered in a new era of Wisconsin basketball.
While their success may be of the more recent and modern variety, the Badgers are led by an old school coach in Bo Ryan, who took over in 2002 and won Big Ten Coach of the Year in his first two seasons.
Ryan has a career winning percentage of .757 and has joined the likes of Wooden, Coach K, Williams, Jerry Tarkanian and Dean Smith in the wins discussion.
Under Ryan, the Badgers have reached 12 straight NCAA tournaments, including five trips to the Sweet 16. Wisconsin has now reached its first Final Four under Ryan and the program's first since 2000 – the year Florida won the national championship.
Bracket Talk
With Florida being the lone team remaining in my bracket (I had Florida, Michigan State, Arizona and Louisville in the Final Four), this is the part where I'm going to admit what went right and what went wrong up until now.
What I got wrong: UConn really messed up my bracket and took out the likes of Michigan State and Iowa State en route to Arlington. The Huskies, like the Wildcats, are a program with players that turn it up a notch come March.
Kansas and Syracuse are two other teams that I expected to go a lot farther than they did, but Dayton was the Cinderella of this year's tournament in my opinion – if we were going to name one that is.
What I got right: Florida was one of the hottest teams heading into the tournament and one of the most popular picks to win it all across the country. The Gators have lived up to expectations. I had Michigan losing in the Elite Eight, but had them losing to Louisville. Still, Florida is a team I believe lived up to expectations for the most part.
It's going to be hard for coach Greg Marshall and the Wichita State Shockers to win the "You didn't play anyone" argument after losing to Kentucky in the third round – even if it was just by two points.
Biggest surprises of the tournament: I'm going to throw UConn in here and leave Kentucky out just because Kentucky turned it on under John Calipari in March, which is somewhat expected. The Huskies, under Ollie, were not expected to make a Final Four run. Dayton, of course, should be in the mix after knocking off Ohio State and Kansas before losing to Florida.
Creighton surprised me in a disappointing way, getting blown out by Baylor in the third round.
Biggest disappointments of the tournament: Duke, Syracuse and Kansas all had very favorable matchups and none of them made it past the third round of the Tournament. Duke's loss to No. 15-seeded Mercer was the tournament's biggest upset.
Predictions: The Huskies were the last team to beat Florida when the two teams squared off Dec. 2, 2013, in Storrs, Conn. Gator's star in Scottie Wilbekin was out for the final 3 minutes of the game with an injured ankle and UConn's star Shabazz Napier drained a buzzer-beating jumper from the free-throw line to give the Huskies the 65-64 win.
Chris Walker, another key Gator, was out due to eligibility issues, which he has since cleared.
While both teams can boast that they've improved since then, I think the Huskies tank is finally going to run out of gas and Florida will have too much talent to lose to this team twice. The Gators advance to the title game.
The Kentucky-Wisconsin matchup should be a very competitive game as the Badgers are a legit team with the No. 2 seed against arguably the hottest team in the country in the Wildcats. Kentucky just keeps finding ways to win.
The signs started to come when the Wildcats knocked off the No. 1 seed Wichita State and, then, it became even clearer when Aaron Harrison hit a highly-contested 24-footer in the waining seconds to knock off the Wolverines.
Kentucky won't let anything stop it from reaching the title game, and I don't know how, but they will find a way to beat Wisconsin and take on Florida for the fourth time this season – this time for the national title.


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This is a page about postal code of Le Lignon, Vernier, Genève, Canton de Genève, with more professional information like latitude, longitude and online map etc.
This is online map of the address Le Lignon, Vernier, Genève, Canton de Genève. You may use button to move and zoom in / out. The map information is for reference only.
More information about text formats


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- 05-10-2014, 08:19 AM Thread Author #1
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sprint galaxy s3 will not turn on
i have a rooted sph-l710 sprint gs3. i was loading the stock rom and unrooting it which ive done many times before with the same file using the same technique on the same phone. i loaded it via recovery mode zip file and it loaded and succeeded with no problems, then ticked reboot phone now and it shut down and wouldn't come back on. i do know what im doing because i been messing with phones for awhile now i.e rooting, custom roms, ect. i went to restart it and it wont turn on at all. i tried charging a spare battery in a wall spare battery charger and it still wont turn on. when i plug the phone in to charge it the normal way through the charging port, the led dont even light up. its dead like there's no battery in it. does anyone know what i can do to fix this aside from taking it in? Any help is appreciated. thank you.
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Re: sprint galaxy s3 will not turn on
can you get into recovery or download menu
if not buy USb JIG it will force phone to enter recovery menu.
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Re: sprint galaxy s3 will not turn on
Also, try seeing if the battery is bulged. Take it out, set it on a flat surface and spin it. If it does spin easily, it needs to be replaced.
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Re: sprint galaxy s3 will not turn on
You could see if you can find a debrick image for it over on XDA.
Or use a JTAG service (ex. http://mobiletechvideos.mybigcommerc...-brick-repair/).
Sent from my rooted, debloated, deodexed Sinclair ZX-80 running CM -0.001 using Tapatalk
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Mort Geller 68 international official dies of heart failure
Mort Geller of Hollywood, Fla., 68, a respected international wrestling official, died July 25 in Florida of congenital heart failure. Geller was the 1999 USA Wrestling Official of the Year, based upon a career of achievement and service as a referee. Geller was involved in wrestling officiating for 30 years and achieved the highest rank as an international referee. He worked in the Olympic Games as a referee representing Israel. He also worked numerous top international events across the world on many levels. Geller received the Phil Portuese Award for his work as a teacher and mentor for young officials. According to U.S. Olympic Wrestling Officials Association President Rick Tucci, he was a valued counselor for him, as well as the rest of the U.S. officials. Geller was originally from Illinois.


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Having roots early in eBay's history, 2wheelsport started out in 1998 as a small ebay business selling old bike parts. Over the years it has grown into a speciality online shop that provides consignment services to individuals and liquidation services to the bike industry. Bike shops liquidate old inventory. Reps sell their end of season goods. Clubs and teams can sell old gear.
Always looking for high end consignments and buying inventory.
18 years on ebay. Platinum Powerseller. See feedback here. http://feedback.ebay.com/ws/eBayISAPI.dll?ViewFeedback2&userid=2wheelsport&ftab=AllFeedback
The best prices for bikes, frames, and wheelsets will be here on the site. All the latest inventory will be posted in the ebay store. stores.ebay.com/2wheelsport


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Word mark
Trademark: 'EZBOND'
On 31. 5. 1999 the community trademark application no. 001190388 was filed for EZBOND (Word mark) by TAIWAN SEMICONDUCTOR MANUFACTURING CO., LTD. before the OAMI.The goods and services in respect of which registration of the trademark was sought are in classes 9 and 42. The current status of the trademark is registration expired.
Status is 'Registration expired'
The Community Trade Mark has not been renewed by the trademark owner and has therefore expired.
|30. 1. 2001
|Expiry date
|31. 5. 2009
|Nice classes
|9, 42
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