text:
A meeting of the Governance Committee was held at the Authority's offices at 123 Main Street, White Plains, New York at approximately 8:30 a.m.
The following Members of the Governance Committee were present:
Michael J. Townsend Chairman
Gil Quiniones President and Chief Executive Officer
Judith McCarthy Executive Vice President and General Counsel
Edward Welz Acting Chief Operating Officer
Donald Russak Acting Chief Financial Officer
Joan Tursi Senior Vice President – Corporate Support Services
Joseph Gryzlo Vice President and Chief Ethics and Compliance Officer
Patricia Leto Vice President – Procurement
Lesly Pardo Vice President – Internal Audit
Brian McElroy Treasurer
Karen Delince Corporate Secretary
Dennis Eccleston Chief Information Officer
Rod Mullin Director – Fuel Planning and Operations
Mark O'Connor Director – Real Estate
Saul Rojas NERC Reliability Compliance Program Manager
Gary Schmid Manager Network Services, Infrastructure
Lorna Johnson Assistant Corporate Secretary
Louise Nestler Assistant Ethics Officer
Sheila Baughman Senior Secretary, Corporate Secretary's Office
Chairman Nicandri welcomed committee and staff members to the meeting.
1. Adoption of the Proposed Meeting Agenda
By motion made and seconded, the March 27, 2012 meeting agenda was adopted.
2. Minutes of the Regular Meeting of November 15, 2011
The minutes of the Committee's November 15, 2011 meeting were adopted.
3. Review and Recommendation of Employee Corporate Policies
Ms. Joan Tursi presented the highlights of staff's recommendation to the Committee. She said Section 2824 of the Public Authorities Law requires the Authority's Trustees to establish policies regarding the payment of salary, compensation, reimbursements and time and attendance of the Authority's employees. Also, Section 2 of the Authority's By-laws requires the Authority's Trustees to annually review and approve these policies.
Ms. Tursi said the proposed changes to the policies are to provide clarity, transparency and accountability and address organizational changes. She then outlined the significant changes to each policy. The policies are as follows:
3.1 Salary Administration Policy (EP 2.1)
3.2 Salaried Non-Exempt and Facility-Based Exempt Overtime (EP 2.4)
3.3 Employee Benefits Eligibility (EP 3.1)
3.4 Reimbursement of Employee Meal Costs (CAP 1.5)
3.5 Attendance & Flexible Hours (EP 4.6)
3.6 Vacation (EP 3.2)
3.7 Travel (CP 2-1)
In response to a question from Trustee Mark O'Luck, Ms. Tursi said the Salary Administration Policy was revised to provide restrictions on promotional increases. If a promotional increase is more than 10%, it has to be approved by the Compensation Committee, with final approval by the President and Chief Executive Officer. President Quiniones added that promotions for Vice President and above, has to be approved by the Governance Committee and the Board of Trustees.
Responding to further question from Trustee O'Luck, Ms. Tursi said that the incentive pay is usually a lump-sum payment awarded for special achievements. The language was added back to the policy in order that management would be able to make an award for outstanding achievements by employees working on major projects.
Responding to a question from Chairman Nicandri, Ms. Tursi said she would explore and report to the Committee the feasibility and advisability of monetary awards as it relates to employees acting above and beyond the call of duty in instances such as the flood at the Blenheim-Gilboa plant last August, where no parameters are established.
On motion made and seconded the revised corporate policies relating to salary, compensation, reimbursements and time and attendance of the Authority's employees were unanimously approved.
4. Review and Recommendation of Guidelines and Procedures
Ms. Tursi said Ms. Patricia Leto will report on the recommendations for the Authority's Guidelines for Procurement Contracts and the Guidelines and Procedures for the Disposal of Personal Property and Mr. Mark O'Connor will report on the recommendations for the Guidelines and Procedures for the Disposal of Real Property and Guidelines and Procedures for the Acquisition of Real Property.
4.1 Guidelines and Procedures for Procurement Contract
Ms. Leto said the Guidelines for Procurement Contracts have been revised to make it consistent with the law; clarify or improve the Authority's procurement process; and reflect any organizational changes in the Authority. Ms. Leto then highlighted the major revisions relating to the Comptroller's approval or filing of certain Change Orders and prohibitions regarding preparation of specifications by outside consultants.
4.2 Guidelines and Procedures for the Disposal of Personal Property
Ms. Leto said staff reviewed the Guidelines for Personal Property and no substantive changes were being recommended; only organizational changes were recommended.
4.3 Guidelines and Procedures for the Disposal of Real Property
Mr. O'Connor said the Guidelines have been developed by staff pursuant to the Public Authorities Accountability Act to ensure that the Authority's transactions as it relates to the acquisitions and dispositions of real property are transparent to the public while preserving the Authority's ability to assist in economic development.
Mr. O'Connor said the Authority has very little surplus real property; all properties deemed surplus has been identified in the recent relicensing process for St. Lawrence and Niagara Plants.
The Guidelines outline the procedures for:
· Acquisition, disposal and valuation of real property
· Inventory control over Authority assets
· Compliance overview
· Duties of the Director of Real Estate
· Ethical considerations
· Annual reporting
4.4 Guidelines and Procedures for the Acquisition of Real Property
Mr. O'Connor said that the only substantive change in the 2012 Guidelines is a change in title, which reflects operational changes made within the past year. The Senior Vice President – Corporate Support Services is named as the Authority's contracting officer.
Mr. O'Connor also said that under the Authority's current expenditure authorization procedure, all acquisitions by eminent domain and all acquisitions or disposals greater than $10k must be submitted separately to the Authority's Trustees for approval.
By motions made and seconded the Guidelines for Procurement Contracts; Guidelines and Procedures for the Disposal of Personal Property; Guidelines and Procedures for the Disposal of Real Property; and Guidelines and Procedures for the Acquisition of Real Property were unanimously approved.
5. Procurement and Real Estate Reports
Ms. Joan Tursi said that status reports on procurement and real estate activities for the period ended December 31, 2011 will be presented.
5.1 Procurement Contract Activity
Ms. Patricia Leto highlighted the following procurement contract activities:
· The total expenditures for procurement contracts for the period ended December 31, 2011 exceeded
$371 million;
· 12% of the contracts were for construction work;
· 47% for the purchase of equipment and commodities;
· 10% for personal service contracts (professional consulting services);
· 2% for architectural and engineering services
· 2% for legal services
· 27% for other service-based contracts;
· approximately 97% of the total amount expended were for contracts that were competitively bid.
5.2 Disposal of Personal Property
Ms. Leto said that under the Public Authorities Accountability Act ("PAAA"), the Authority is required to prepare a report listing all personal property over $5000 in value disposed of during the reporting period. For the period ended December 31, 2011, there were 15 such transactions. The Authority received $803,328.12 for these transactions.
Fleet Operations
Ms. Leto said that during the reporting period ended December 31, 2011, the Authority participated in four fleet-related auctions conducted by JJ Kane Auctioneers. The Authority received $725,080.85 after commission and transportation costs were deducted.
The total amount for all personal property with a value in excess of $5,000 for the reporting period is $1,528,408.97.
In response to a question from Trustee O'Luck, Ms. Leto said Authority staff estimates the value of the fleet for auction or uses an outside firm. Ms. Tursi added that the Authority usually receives more than estimated at the auctions because bidders are aware that the Authority's vehicles are properly maintained.
5.3 Acquisition and Disposal of Real Property
Mr. Mark O'Connor reported on the acquisition and disposal of real property, as well as leasing and permitting activities for the period ended December 31, 2011.
The Real Estate division closed on several acquisitions during the reporting period. Of note, is a series of transactions with Noble Wind Energy which has helped to facilitate wind energy development in Clinton County. Also, staff closed on a substation and underground facilities to facilitate construction of the Astoria Energy Generating Facility in Queens, New York.
Danger Tree Permits
This program allows the Authority to acquire transmission right-of-way permits for vegetation which has grown to a sufficient height to threaten the safe operation of its transmission system. One of the components of the North American Electric Reliability Corporation ("NERC") compliance standards is a successful vegetation maintenance program. During this reporting period, staff closed on a total of 88 danger tree permits.
Land use permits
The Real Estate division issued 16 land use permits during calendar year 2011. These permits are issued by the Authority to allow others to use its land holdings (normally its easement rights) in a safe and productive way and consistent with the safe operation of its transmission facilities.
Headquarters Leasing
The Authority owns the building at 123 Main Street and occupies approximately 60% of it. Approximately 40% of the building is occupied by lease-paying tenants. This leasing operation generates about $2.7 million in gross revenue. As indicated at the last meeting, JP Morgan Chase has vacated its leasehold on the 4th floor.
Staff is currently attempting to market this space, with the Authority's broker, Newmark Knight Frank, but market conditions continue to be unfavorable. In the White Plains Central Business District, with 5.9 million square-feet of office space, more than 20% is considered open and available for leasing. Further, the trend is currently showing more available space placed on the market than is being absorbed. The trend is also toward negotiations of smaller deals. For example, at least three of the Authority's tenants have requested modifications to their existing leases because they are unable to meet their rental obligations. Staff is working to address this issue which reflects the overall economic conditions for the businesses involved. The Board of Trustees will be requested to approve any concessions made with tenants.
New York Office Lease
The Authority leases a small office space of approximately 7,100 rentable square feet at 501 7th Avenue in midtown Manhattan. This lease, by its terms, expires on August 31, 2012.
St. Lawrence lands
One of the major commitments the Authority made during the relicensing of the St. Lawrence/FDR Power Project was to convey certain identified lands as surplus to either municipalities or landowners who owned adjoining lands to these Authority lands. To date, staff has conveyed all of the lands committed to various municipalities of Lisbon, Louisville, Waddington and Massena. In addition, of the 520 parcels committed to private landowners, approximately 412 parcels have been conveyed. Staff is working to persuade the landowners to close on the remaining parcels.
In response to a question from Trustee O'Luck, Mr. O'Connor said that the land conveyed to the municipalities was in the amount of $1 with payment waived; and the land conveyed to individual landowners was at fair market value. The lands were individually appraised and made public.
In response to further question from Trustee O'Luck, President Quiniones said that with regard to office space in New York City, the Authority is exploring different options including sharing of space with other New York State agencies. However, a final decision has not yet been made.
5.4 Supplier Diversity Program Activities
Ms. Leto reported that for the period ended December 31, 2011, the Authority awarded $61.2 million (18.6%) of its reportable expenditures to New York State ("NYS") Certified Minority and Women-Owned Business Enterprises (M/WBEs). M/WBEs financial dealers transacted over $421.8 million in principal sales and purchases for the Authority. The Authority also increased its contract allocations to MWBEs from 6% to 20% in support of the Governor's goal for M/WBEs to account for 20% of NYS businesses. The bulk of these allocations will be through energy services projects.
In response to a question from Chairman Nicandri, Ms. Leto said that staff uses the NYS Registry list of MWBEs to verify that all applications being submitted are certified by NYS.
5.5 Inventory Statistics
Ms. Leto reported that as of December 31, 2011, the total stock value of the Authority's inventory was $84,046,879. This includes spare part materials for the Blenhein-Gilboa Life Extension and Modernization project, purchase of spare gas compressor, compressor blades and Original Equipment Manufacturer ("OEM") valves for the 500 MW Project.
5.6 Fossil Fuels Activity
Mr. Rod Mullin reported that the total fuel purchases and related costs for the period ended December 31, 2011 was $260 million. Of this total, $251 million was spent on Natural Gas purchases and associated costs and $9 million on Fuel Oil purchases and related costs. There were 30 natural gas and oil contracts, in total, all of which were competitively bid. To date, the Authority has transacted approximately $5.5 million of business with the firm of YAKA Energy, a certified NYS M/WBE.
Mr. Mullin said that the natural gas industry has been experiencing low prices recently and this is expected to continue for some time. This is due primarily to weak demand, high storage, new sources of natural gas and new technology.
5.7 Corporate Finance Activity
Mr. Brian McElroy stated that for the year ending December 31, 2011, the Authority expended approximately $4.5 million on financial related agreements primarily supporting the administration of the Authority's variable rate debt program, namely the Commercial Paper Notes and Adjustable Rate Tender Notes. Approximately 80% of the expenditures were related to the 2011 Revolving Credit Agreement which the Trustees approved in January 2011 for a term of three years. Mr. McElroy also noted that the Commercial Paper Notes are trading around 20 basis points and the Adjustable Rate Tender Notes recently reset for a six month term at 15 basis points.
In response to a question from Chairman Nicandri regarding recent headlines of the Port Authority's use of interest rate hedging instruments, Mr. McElroy said that the Authority has two open interest rate swaps matched with underlying variable rate debt. Therefore, the Authority does not have any un-covered positions.
6. Recent Development and Status of NYPA's Ethics and Compliance Program
Mr. Joseph Gryzlo provided an update of the Authority's Ethics and Compliance program. He said that the Ethics and Compliance office continues to receive ethics inquiries from staff, including union employees, the main category being with regard to outside employment. Outside Activities and Employment were the focus of NYPA's annual ethics training which was administered to all Trustees and employees during the first quarter of 2012. He added that union employees were not subject to the Authority's Code of Ethics until 2009 when it was revised. The Ethics office also received requests for interpretation of the Public Officers Law and the Authority's Code of Conduct involving issues related to conflicts of interest, endorsements, gifts and post-employment restrictions.
Financial Disclosure
Mr. Gryzlo said that the deadline for filing Financial Disclosure statements is May 15th. The Ethics office will be sending e-mails to the Trustees and staff who are required to file. Approximately 400 employees are required to file.
Inspector General's Office - Referrals
Mr. Gryzlo reported that the Ethics and Compliance office received two referrals from the New York State Inspector General's Office.
Mr. Gryzlo said that the annual Federal Energy Regulatory Commission ("FERC") Standards of Conduct training has been completed by all Authority employees who are required to do so.
Compliance Update
Mr. Saul Rojas provided an update of the North American Electric Reliability Corporation ("NERC") Reliability Standard Compliance Program. He said that the Authority self-reported four potential violations to the Northeast Power Coordinating Council ("NPCC") in 2011:
· PRC-005-1 R2 – Maintenance and Testing of Transmission and Generation Protection System: The NPCC is reviewing the results of NYPA's recently completed mitigation plan. NYPA will soon enter into settlement discussions with NPCC and a penalty is expected.
· PRC-018-1 R6 – Maintenance and Testing of Disturbance Monitoring Equipment: NYPA's self-reported violation of this requirement was processed through NERC's Find, Fix and Track process and filed with FERC on February 29, 2012. Therefore, no financial penalty was assessed.
· CIP-004-3 R2 and CIP-0043 R4 - Cyber Security — Personnel and Training: NYPA's self-reported violation of these requirements will be processed through NERC's Find, Fix and Track process; therefore, no financial penalty will be assessed.
Responding to a question from Trustee O'Luck, Mr. Eccleston said staff ensures that the security of the Authority's cyber and transmission systems are protected against attacks. President Quiniones added that the Authority is investing the appropriate resources into the protection of its physical and cyber security. This is an ongoing process and standards are being set by NERC and FERC to address this issue.
Bulk Electric System Definition:
Mr. Rojas reported that FERC issued its final rule on the Electric Reliability Organization Definition of the Bulk Electric System ("BES") to include assets greater than 100 KV. He said NERC approved the new BES Definition and the Exception Process and filed them with FERC on January 25, 2012. FERC is expected to adopt the new definition and exception process by the end of 2012. The new BES definition will have substantive impacts on New York State's electric utilities, including NYPA. NYPA has identified 25 additional assets that will be subject to NERC Reliability Standards under the new definition and is working with NPCC and NYISO to address this issue.
CIP Standard Version 5
Mr. Rojas reported that a new version of the Critical Infrastructure Protection ("CIP") standards regarding cyber security in the electric utility industry is currently being developed and is expected to be adopted by FERC by the end of 2012 and be enforceable in 2014. He said staff will keep the Committee apprised of any new developments as it is expected that the new standards will have significant impacts on the Authority.
7. Proposed Strategic Planning and Energy Committee Charter
Ms. Judith McCarthy provided highlights of the proposed Strategic Planning and Energy Committee Charter.
By motion made and seconded, the Strategic Planning and Energy Committee Charter was unanimously approved.
8. Motion to Conduct an Executive Session
Mr. Chairman, I move that the Authority conduct an executive session pursuant to the Public Officers Law of the State of New York section §105 to discuss matters leading to the appointment, employment, promotion, demotion, discipline, suspension, dismissal or removal of a particular person or corporation.
On motion made and seconded, an Executive Session was held.
9. Motion to Resume Meeting in Open Session
Mr. Chairman, I move to resume the meeting in Open Session. On motion made and seconded, the meeting resumed in Open Session.
10. Amendments of NYPA By-laws
Ms. Judith McCarthy stated that the By-laws were amended to establish a set of procedures for the Authority that would be longstanding; this will avoid ongoing amendments to the By-laws. The amendments also address the Trustees concerns with regard to the reporting structures of the Chief Financial Officer and the General Counsel. Ms. McCarthy said the amendments reflect staff's findings after review of the reporting structures of other utilities and authorities. The By-laws also reflect the establishment of the Strategic Planning and Energy Policy Committee.
President Quiniones added that the Authority's goal is to conform to best practices with comparable agencies and large utilities of the state. He said the Strategic Planning and Energy Policy Committee is crucial in the Authority's mission to play an active role in advancing the state's energy and economic development goals.
In response to a question from Chairman Nicandri, Ms. McCarthy said that the change as it relates to the reporting structure of the Chief Financial Officer was based on staff's findings. She then suggested that the Committee could discuss this further during the Executive Session before formal adoption of the amendments.
Following the Executive Session, Ms. McCarthy said that the proposed amendments to the By-laws were further amended as follows:
Section (h) Executive Vice President and Chief Financial Officer, page 5:
amendment bolded.
The Executive Vice President and Chief Financial Officer shall report and give advice to the President and Chief Executive Officer, shall give advice to the Chair and Trustees as they may request and shall supervise and direct the activities of the Business Services Division regarding financial investment policies of the Authority, oversee the Authority's investment program, recommend and implement financial policies of the Authority and participate in the preparation of the financial reports of the Authority required by the applicable law.
By motion made and seconded the proposed amendments to the Authority's By-laws were unanimously approved.
11. Next Meeting
The next regular meeting of the Governance Committee will be held on Tuesday, July 31, 2012, at 8:30 a.m., at the Clarence D. Rappleyea Building in White Plains, New York.
On motion made and seconded the meeting adjourned at approximately 10:35 a.m.


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I'm saying that when you have so many good teams the odds that at least one of them has a record better than 13-5 are higher. You're going the other way which is to think that they will all beat each other up. I suppose either could happen.
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I'm saying that when you have so many good teams the odds that at least one of them has a record better than 13-5 are higher. You're going the other way which is to think that they will all beat each other up. I suppose either could happen.
Hopefully we blow out Penn State tonight and also escape uninjured. I hated playing this team last year, they play reckless basketball and have no problem diving through someone's knees. I will be holding my breath all game.
We will be number 5 and Minny will be number 8 for our matchup this Saturday.
They beat us in the Hall last year. Our only loss there. I'm guessing our boys haven't forgotten that.
After giving up 13 offensive rebounds to Penn freaking State I worry how we'll fare against Mbakwe and company.
The second half tonight was garbage. IU got lazy and coasted.
No doubt. Need some rough practices between now and Saturday.
That being said though, to put what happened yesterday in perspective, only one team last season in the B1G had a 20 point road win and that was OSU, they did it a couple times.
Last edited by Trader Joe; 01-08-2013 at 12:41 PM.
Rebounding/physicality and the possibility of really bad matchup for Hulls to defend are my two biggest concerns. Our offensive arsenal is neutralized by not securing the defensive boards. I think we're good enough to overcome for the most part, but there's always that chance it rears its ugly head at the most inopportune time.
I'd rather die standing up than live on my knees.
-Emiliano Zapata
This IU/Minnesota game has been awesome so far. The IU crowd is freakin' outstanding... not that I'm surprised.
Take me out to the black, tell 'em I ain't coming back. Burn the land and boil the sea, you can't take the sky from me.
I absolutely hate it when this team plays zone. Why, Crean? It almost never works.
Minn has been hot from 3 so far.
Hulls is feeling it. Baaaad news for the Yellow Rodents.
If Victor continues to hit threes consistently, he's a first team All-American.
All of these threes--credit them to Yogi. He's setting the table expertly.
Everyone's doing it for IU today. Zeller, Watford, Oladipo, Hulls, and Ferrell have all taken over in spurts. No one on Minny has been able to establish themselves.
Take me out to the black, tell 'em I ain't coming back. Burn the land and boil the sea, you can't take the sky from me.
OH. MY. GOD. That last play! Oladipo with the steal to Zeller to Ferrell!!!!
Take me out to the black, tell 'em I ain't coming back. Burn the land and boil the sea, you can't take the sky from me.
"Nobody wants to play against Tyler Hansbrough NO BODY!" ~ Frank Vogel
"And David put his hand in the bag and took out a stone and slung it. And it struck the Philistine on the head and he fell to the ground. Amen. "
Want your own "Just Say No to Kamen" from @mkroeger pic? http://twitpic.com/a3hmca
That second half was officially horrible by IU, but at least they came out with a win. 3-0 in the Big Ten now.
Take me out to the black, tell 'em I ain't coming back. Burn the land and boil the sea, you can't take the sky from me.
Didn't get to see the second half (stuck at work). How did Minney get so close?
Skip Bayless:
"Derek Fisher will prove to be a much better NBA head coach than Steve Kerr."
"The Houston Texans will forever regret it if they do not take Johnny Manziel with the No. 1 overall pick. He will haunt them."
"You bet I'd take Tebow late in games over ARodg."
"Manti Te'o: the next Ray Lewis."
What a weird game. 3 point sfrom th bench? Yikes. A little too complacent in the first half. Don't understand why Watford takes the ball out for us. He is a good screener we should use him in that role when we are being pressured and either have yogi or hulls take it out. We don't really throw the ball deep over people, it is usually a bounce pass so why not let our two guards try and work somethign?
Oladipo is fantastic, but made some boneheaded mistakes. Can't believe we missed those free throws, we need to work on keeping our pace up even when a game is getting mucked up with fouls.
I was pretty upset after that second half but in the end it's tough to stay angry when you basically beat a top 10 team wire to wire like that.
Oladipo with three inexcusable fouls. I'd love to know how many times a guy has committed THREE fouls on a guy shooting a three pointer in the same game. You just can't do that.
I texted a buddy right afterward: "That was about the most deflating win over a top 10 team I can imagine. Not sure how to feel right now."
The last four-five minutes were terrible by IU but give credit to Minny. They are a legit top ten team.
At the end of the day, IU is 15-1 and poised to move up to #3 in the polls on Monday.
Possibly 2, not that I am cheering for OSU or anything
One more thing to add about the game yesterday. That is how teams should try to use the 3 ball to get back in a game. All so often teams wait till they have to hit every single 3 to make it back into the game. Minny started early, which gave them the chance to miss some yet still get back in the game.
Last edited by Mad-Mad-Mario; 01-13-2013 at 12:09 PM.
Oh, I am rooting for OSU. Absolutely. Then again, I live in the heart of Michigan country and have several friends who are Wolverine fans. They are getting awfully cocky. I'd like to see them taken down a notch.

subset: commoncrawl


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Hi Alex,
That type of issue is usually fixable, but it may need to be looked at by a professional repair shop.
Have you had this problem for a while, or is this a new issue?
Hi Alex,
That type of issue is usually fixable, but it may need to be looked at by a professional repair shop.
Have you had this problem for a while, or is this a new issue?
I've had the issue since it was installed by a professional. I've mostly used the guitar unplugged but now I'd like to use it plugged in as it sounds amazing except for the one string. I'd prefer to do the repair myself but I needed to know if it was fixable and what needs to be done. Am I correct in assuming the saddle needs to be raised on the high E side?
Thanks again for your help,
The reason I recommend using a professional is that the LB6 is a very difficult pickup to work with. You may be able to add a thin layer of black electrical tape to the bottom of the brass sensor, under the quiet string. Beyond that, a professional with LB6 experience is highly recommended.
Thanks, Caleb. I'll give it a shot and try to locate an experienced professional if I hit a dead end.
Has anyone powered a the Venue Di with the Voodoo Lab Power Plus 2 and knows what configuration is needed to properly power the Venue?
Hey baotloi,
Welcome to the LR Baggs forum!
You should be able to use one of the regular 9v (center neg) outputs from the Power Plus 2, with one of the included 5.5 x 2.1mm plugs. The PP2 is already designed to provide the necessary power that the Venue needs, so it's just that simple.
I know several people who use the PP2 with their Venues right now, and they all have really good things to say about their setups.
All the best!
Thanks Caleb! I'm new to this pedal board thing although I've been playing for about 10 years now. I've been using mainly multi-effects board like Line6 POD system for my electric and recently bought a HD-35 with the Venue Di, Boss DD-20, and a TC Hall of Fame. Let me know if you have any recommendations!
Thanks for the help!
I have the TC Hall Of Fame, and I LOVE it! It's an excellent pedal for Electric and Acoustic guitars. I run my HOF in the Venue FX loop, when I use use it. That way, my tuner stays accurate without needing to disengage the Reverb.
I just received two Element active undersaddle pickups for two guitars that I own. I installed both, and one of them was humming A LOT, while the other works perfectly. I took both pickups back out, and noticed that on the one that is humming, the small, exposed metal at the end of the undersaddle "string" was missing. I am assuming this is some sort of grounding device? Is this something that I can fix without sending the pick up back...or will this require a swap out?


text:
PRO stands for Player Referee Organization. It is the standard name given to AYSO Referee programs geared towards kids 18 years old and younger. Anyone is welcome to become a youth referee – they do not have to be a soccer player to join PRO. However, 95% of AYSO youth referees are also soccer players and therefore the program is named Player Referee Organization.
National guidelines state that kids 12 years old and older can become certified Referees (U-5 thru U-8 games) or Regional Referees (U-5 thru U-10 games). Youths under 12 are welcome too, but usually need to join the program as Assistant Referees.
For more info, please contact the PRO directors at email@example.com .


text:
Poorly trained part-timers determine test scores that loom so large in education, writes Todd Farley in a New York Times op-ed. The author of Making the Grades, Farley was hired to score fourth-grade, state-wide reading comprehension tests when he was a graduate student in 1994.
One of the tests I scored had students read a passage about bicycle safety. They were then instructed to draw a poster that illustrated a rule that was indicated in the text. We would award one point for a poster that included a correct rule and zero for a drawing that did not.
The first poster I saw was a drawing of a young cyclist, a helmet tightly attached to his head, flying his bike over a canal filled with flaming oil, his two arms waving wildly in the air. I stared at the response for minutes. Was this a picture of a helmet-wearing child who understood the basic rules of bike safety? Or was it meant to portray a youngster killing himself on two wheels?
Some fellow scorers wanted to give full marks for understanding bicycle safety; others wanted to give a zero.
I realized then — an epiphany confirmed over a decade and a half of experience in the testing industry — that the score any student would earn mostly depended on which temporary employee viewed his response.
This is why multiple-choice tests can be more reliable than subjectively graded tests that rely on drawing (or writing) skills to measure reading comprehension.
I have a review copy of Farley's book, which I plan to read very soon — along with the four other review books waiting for me. Maybe today! Anyhow, I vowed not to mention other people's books without promoting my own book, Our School: The Inspiring Story of Two Teachers, One Big Idea and the Charter School That Beat the Odds.


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RAGE Pull Up Assist System
Product Information:
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Country of Origin: United StatesWeb ID: 13270936
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Rated 5 out of 5�by kingfischer great product Gives you the ability to lower resistance over time. Gives you full.range of motion and keeps you in correct form unlike using the "chair technique" to assist your pull ups. Recommended for P90x. September 26, 2014
Rated 5 out of 5�by tnacc Pull up assist It allows me to do pull ups with a full range of motion. December 9, 2013
Rated 3 out of 5�by CF2013 Good price, but quality questionable Purchased this product for use in training strict pullups. No instructions included, but it's pretty simple to figure out and install on my pullup bar. The bands are not manufactured in a complete circle, but are glued together to make one. Hope the glue holds up, because it makes me nervous about the adhesive failing when I have my body weight on it. This is not easily seen by the way the product is packaged in the box. Also, the green paint or whatever it is that is used to apply the company logo to the bands came off all over my hands and does not wash off easily. Yes, this product is less expensive than purchasing traditional CF bands, and it's nice to have the flexibility of increasing the resistance, but I don't think this product is manufactured as well as it could be. July 4, 2013
Rated 5 out of 5�by Andi Just what I was looking for. I was going to just get a heavier gauge resistance band for my assisted pull ups and then I saw this. Easy to install onto my pull up bar. The fact that it comes with three bands is great because you can start with three, build up strength, move onto only using two and so on and so forth until you can do a pull up unassisted. For me I only use one band, but other people use our home gym who need the use of all three. So it's good for all of us. It mimics the form of a strict pull up much better than some other methods of assisted pull ups, for example putting one foot on a chair. I think for anyone working on doing a strict pull up unassisted this is the perfect tool. Simple and very effective. March 19, 2013
Rated 4 out of 5�by Al GREAT product, but no directions. Great product & the use is pretty straight forward, but it would have helped if there were some "tips" of us maybe or "things NOT to do," but overall once it was all figured out good product for the price. October 21, 2012
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Topic: dzone - Digg for Developers
I just came across this site called dzone which is basically Digg for developers. It now has a Ruby category, and so I just added a link for Rails Forum:
http://www.dzone.com/links/rails_forum_ by_on.html
Digg has it's own programming section, but the RoR content is a little sparse and it is very tough to get stuff on the main page there, so dzone may be a better place to find RoR content.
Feel free to post any interesting stuff to dzone that you do here.
Rails Forum - Rails Jobs


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Showing 2,785-2,880 of 3,187 items
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The Filling Station Pub and Grill
Offering a variety of meals, burgers, sandwiches, fajitas and roasted cod (all you can eat on Fridays). Old gas station memorabilia.
CITY:St. Charles
An ode to the American table with its diversity and global influence. We set out to be an expressive regional American kitchen, all while remaining approachable, affordable, and welcoming.
CITY:St. Charles
Main dining room has a ski lodge atmosphere. Exposed brick walls. All season outdoor garden. Seventeen TVs for all major sporting events.
This is the ultimate destination for anyone who loves sports. The only sports bar with 22 projection TVs and 140 flat screen TVs. If your sport is on TV they have it! OTB, slots, shuffleboard tables, pool tables, sand volleyball, team trivia, indoor tobacco shop and lounge. Fantastic menu, MUG club and drink specials. Three separate bars and private spaces available for catered parties. Salsa dancing w lessons featured on Tuesday's and Friday's as well as Team Trivia Tuesday's and Thursday's.
The Fudge Pot in Chicago provides delicious chocolate, daily. Their specialists' work around the clock making sure only the sweetest covered strawberries, apples and nuts are provided. Take your pick of famous toffees, award winning fudge and chocolate bars. You can always expect only the tastiest treats at The Fudge Pot.
Chicago's first and only Gastro Tavern. High-quality food, a step above pub grub, in a relaxed atmosphere. Menu complemented by assortment of international beers, wines and liquors and our specialty Irish whiskeys.
The Garden Cafe & Lounge, Doubletree Hotel
Pasta and salad bar for lunch, weekdays. Steaks, chops and poultry dishes for dinner in a casual atmosphere.
CITY:Wood Dale
A landmark in Lockport and along the I&M Canal since 1838, The Gaylord Building connects visitors to America's forgotten Canal Era. Come tour the site and enjoy fine dining in the Public Landing Restaurant. Then stroll or bike ride along the scenic canal trail or explore Lockport's National Register Historic District. Monday - Saturday 10:00 AM - 5:00 PM and Sunday 11:00 AM - 5:00 PM. Special group tours by appointment. The Gaylord Building is a historic site of the National Trust for Historic Preservation (www.preservationnation.org). The Gaylord Building played a vital role in one of the great enterprises of the 19th century: the Illinois & Michigan Canal. In this handsome limestone warehouse visitors will discover exhibitions illustrating the unique heritage of the site and the Canal Corridor. A landmark in Lockport and along the I&M Canal since 1838, The Gaylord Building connects visitors to America's forgotten Canal Era. Come tour the site and enjoy fine dining in the Public Landing Restaurant. Then stroll or bike ride along the scenic canal trail or explore Lockport's National Register Historic District. Special group tours by appointment. The Gaylord building is a historic site of the National Trust for Historic Preservation (www.preservationnation.org). Monday - Saturday 10:00 AM - 5:00 PM and Sunday 11:00 AM - 5:00 PM.
The Gene Siskel Film Center - School of the Art Institute of Chicago
One of the largest and most comprehensive programs of its kind in the country, the Gene Siskel Film Center presents premieres of new American and foreign films, revivals of classics, retrospectives, independent productions, and festivals of international scope. Open to the public seven days a week, $11 general admission, $8 groups, $7 for students. Visit our website at siskelfilmcenter.org for more information.
Come for business, stay for golf. The Glen Club has 21 overnight rooms featuring unique layouts and elegant fixtures including historic photographs from Chicago's famous Golf Clubs. Dine on delicious American fare at "The Grill" or host your corporate events in our elegant ballroom seating up to 230, or our stately meeting rooms. Visit the Illinois Golf Hall of Fame. Designed by renowned golf course architect Tom Fazio, the Glen Club's golf course features rolling terrain with dramatic elevation changes, meandering lakes and streams and stunning vistas.
This perfectly-planned town offers beautiful shop and restaurant-lined streets—just like a European town. A 10-screen movie theater, shops including Von Maur, Hot Mama and Dick's Sporting Goods as well as restaurants unique to the North Shore including RA Sushi, Jameson's Charhouse and Ted's Montana Grill. The Glen Town Center is also home to the Kohl Children's Museum, a leading institution for hands-on, interactive learning.
Come find a taste of Greece! Try traditional specialties like Leg of Lamb, Pastichio, Spanakotiropita, Dolmades, Loukoumades, and Moussaka. Belly Dancer every Friday and Saturday night followed by Live Music. Semi-private dining with party packages.
The Green Door Tavern of Chicago
From its earliest days, The Green Door Tavern has been a neighborhood favorite. It's warm wooden interiors, decorative backsplash of memorabilia from days long past, and down-to-earth staff have kept its many loyal customers happy through Chicago's bitter winters to its hot, summer nights. Over the years the menu has changed, but the theme has remained the same – "eat, drink, be merry"…and occasionally cheer for Chicago's winning sports stars – the Bears, Bulls, Hawks, Sox and Cubs.
The Grille, Oak Brook Hills Resort
Just steps away from the 18th hole where you can relax and enjoy a light meal and refreshing beverage. Specialty drinks and all-you-can-eat Friday night fish fry
CITY:Oak Brook
The Grove National Historic Landmark
The prairie grove, covering 123 acres of ecologically diverse prairie land, is preserved and maintained as former home of the visionary horticulturist and educator Dr. John Kennicott, who brought his family from New Orleans to settle on his land in 1836. The Grove, located in Glenview, is a National Historic Landmark and is on the National Registry of Historic Places. It offers many opportunities for educational, environmental and historical enjoyment including two historic homes, the Kennicott House and the Redfield Estate; the Grove Interpretive Center, a Native American Village, a Log Cabin, a Schoolhouse, a Wetlands Greenhouse and numerous interpretive trails.
The Guesthouse Hotel - Chicago
The Guesthouse Hotel offers spacious, affordably luxurious, and fully furnished 2 bed / 2 bath and 3 bed / 2 bath vacation rental condominiums. Located on the southern end of Andersonville, one of Chicago's hottest neighborhoods, the Guesthouse is very close to public transportation for convenient access to downtown Chicago and tourist attractions. The affordable luxury of our Guesthouse and our unique location provide the perfect rental accommodation for travelers who want the comforts and independence of their own home while enjoying all that Chicago and its local culture has to offer.
World's largest manufacturer of art pottery. Factory outlet salesroom and Haeger Museum open to the public at original manufacturing site.
CITY:East Dundee
Nestled in to the banks of the Fox River, The Herrington offers romantic getaways, executive events, weddings, corporate events, and riverside dining 45 minutes from downtown Chicago.
The Highlands of Elgin Golf Course
This collection of eighteen holes now provides golfers with an adventure through a variety of unique golf holes in a beautiful setting. The prairie style clubhouse features an expanded golf shop, locker rooms, event rooms with expansive ceilings and a full scale food and beverage operations. Enjoy dining at the Hickory Stick Bar & Grill and experience stunning golf course views.
The Highlands of Elgin Golf Course
The Highlands of Elgin has become a premier destination for thousands of golfers throughout the region. Nine new holes reclaim an old stone quarry, and take maximum advantage of the unique and dramatic landforms that were left behind, including a twelve acre quarry lake. Four holes hug the top of the bluff thirty to forty feet above the water providing golfers with incredible views and numerous shot options on each hole.
Built in the historic Williamsburg-style in 1927, the Homestead has been under family management for over 75 years. The 90-room hotel is conveniently located on a quiet residential street adjacent to Evanston's downtown business district and Lake Michigan. Guests will enjoy a continental breakfast and garage parking during their overnight, or longer stay (rooms can be rented by the day, month or longer.) The hotel's fine dining restaurant, Quince, serves contemporary American cuisine and Q2, the hotel's intimate cocktail lounge, is not to be missed.
The Iannelli Studios Heritage Center
Home to the Kalo Foundation of Park Ridge, a nonprofit organization dedicated to preserving the rich artistic legacy of the city through education, advocacy, and preservation, as well as promoting the arts & crafts as an integral part of our modern lives. Based on the ideals of the American Arts and Crafts Movement, the Foundation will sponsor educational seminars, exhibits, tours, publications and special events to increase awareness and appreciation of the arts and crafts. Check the website for special events and hours.
CITY:Park Ridge
The Illinois State Museum Chicago Gallery
The Illinois State Museum Chicago Gallery exhibits and promotes the work of contemporary and historical Illinois artists. The changing exhibition schedule presents Illinois art to a statewide as well as a national and international audience. Our exhibition schedule ranges across mediums, including our outstanding quilt collection in the Decorative Arts area to electronic art, installations, and collaborative exhibitions with community organizations. Admission is free.
Try us for great authentic Mexican tacos and burritos, hot dogs, fresh cut fries, hamburgers and more. Open daily.
CITY:St. Charles
297 rooms. 106 suites. Seven meeting rooms. 200 nonsmoking rooms. One restaurant - David Burke's Primehouse. The Spa. 24-hour room service and concierge service. The second in a dynamic new line of hotels that Travel & Leisure named "America's sexiest." James fuses modern American comfort, service and style with state of the art technology. A multiregional Italian restaurant, JBar and The Gym, our signature fitness center, are highlights. Located at Rush & Ontario at the center of the Magnificent Mile and gateway to River North.
The Joffrey is a world-class, Chicago-based ballet company that performs a unique repertoire encompassing masterpieces of the past and cutting-edge works. Director Gerald Arpino brings a uniquely American style of dance featuring ballets from the great choreographers of the 20th century. Many prolific choreographers have worked with the Joffrey including Paul Taylor, Twyla Tharp, George Balanchine, and founders Gerald Arpino and Robert Joffrey. Photo credit: Joffrey Ballet
Take a kayaking class or a kayaking trip with an ACA certified instructor on the beautiful Fox River, Batavia. It's fun and informative. Check out some videos on what you will learn in the different classes. Several group and private kayaking classes - first time kayakers to intermediate. See the calendar for dates and times. So grab your friends and let's go paddling!
The Keg has a relaxed atmosphere and an inviting dance scene. Come and enjoy a meal or just drink and have a good time.
The Keg of Evanston restaurant
A friendly drinking establishment catering to the North Shore for over two decades. The Keg has a relaxed atmosphere serving everything from steak and seafood to hamburgers.
Known as Chicago's liveliest Irish bar, located in the heart of downtown Chicago's River North Neighborhood, The Kerryman is a little piece of Ireland. The 3 owners all hail from Co. Kerry Ireland and the Head Chef Damo Moloney from Co. Limerick, Ireland who creates an upscale authentic Irish menu.
The Kids' Table is a unique resource created with a single goal in mind: to help instill in kids a love of healthy foods. With cooking classes for tots, kids, teens, parents, and even the whole family, The Kids' Table is a fun, educational environment that gives parents the tools and information they need to get their kids eating well from the start, while encouraging and empowering kids to begin making their own healthy food choices. Our retail store offers an array of products to get parents and kids cooking together at home, as well as a variety of healthy food-themed tees, toys and children's books.
Think of The Kimpton Gray Hotel like a perfectly bespoke suit from London's Savile Row — beautiful, bold, and with no detail out of place. Clad in marble and terra-cotta, The Kimpton Gray has been a tastemaker for more than a century, first as an office building and now as an elevated-experience hotel. When the 9-to-5 day is done in the Financial District, those in the know flock to the on-site restaurants - Volume 39, a law library-themed bar, and Boleo, an Argentinean-inspired rooftop lounge.
The Law Office Pub & Music Hall
Boyd, owner of Rogue Barrister Records has partnered with Jason Leslie, owner of Three Angels Brewing have brought together national talent combined with some of the best local craft beers in the area to provide a one-of-a-kind music and beer experience for visitors and local residents alike. The Law Office Pub & Music Hall is the perfect space to showcase amazing independent musicians and great craft beers on a regular basis. A uniquely remodeled pub and music hall, the Law Office is strategically situated along the majestic Fox River. Open Thursdays - Saturdays.
The Legacy Walk is a dynamic outdoor LGBT history exhibit in the "Lakeview" neighborhood of Chicago. Presently, along the half mile of the North Halsted Street Corridor, between Belmont Avenue and Grace Street, ten (10) pairs of 25'-tall decorative "Rainbow Pylons" define the nexus of Chicago's LGBT community. Affixed to the pylons are a series of bronze memorial plaques commemorating the life and work of notable lesbian, gay, bisexual, or transgender individuals whose achievements have helped shape the world
As stylish and romantic as the European jazz clubs it aims to emulate, the Little Gem Café offers an elegant setting and delectable items using locally sourced ingredients. Featuring weekly live music, happy hour specials, and the recent unveiling of a new weekend brunch menu, the Little Gem will bewitch you with its warm atmosphere and uniquely flavorful dishes. Planning a private party? The event team will work with any budget and size to create your perfect event, from anniversaries to corporate meetings.
CITY:Oak Park
This historic mansion features 36 rooms filled with treasures from around the world and a history over 80 years in the making.
The Little Traveler (Restaurants)
Dine in the Atrium Cafe or at the Victorian Buffet Luncheon served daily in the store's Antique Department where you will enjoy fresh entrees and delicious desserts elegantly served on silver, china and imported antique dishes.
At the Lobby in the world renown Peninsula hotel, guests can enjoy a spectacular dining experience from a five star restaurant while relishing in the opulence and majesty of the space. Traditional afternoon tea is also served daily, while the weekend offers a scrumptious brunch accompanied by a string quartet.
Wood-roasted chicken, ribs. Free s'mores in outdoor fire pit. Seven flat screen TV's to watch sports.
CITY:St. Charles
A family-friendly restaurant featuring Prime beef burgers, thin-crust pizza, and craft-brewed beers, including 6 brewed on the premises.
The ritzy North Michigan Avenue shopping district boasts a dizzying array of stores, including Nordstrom, H&M, Tiffany, Chanel and the flagship Crate & Barrel store. Upscale shopping centers include Water Tower Place and The 900 Shops. In just eight blocks, you can shop at over 420 exclusive stores and boutiques, enjoy fine dining at over 200 restaurants and discover unsurpassed hospitality at over 50 hotels.
Located in a historic 28-room mansion.
CITY:West Dundee
This bed and breakfast's original architecture dates back to 1927 and charms guests with its wood burning fireplace, French doors and vintage molding. The Inn's 42 are each uniquely designed. Personal service is complete with a continental breakfast. Conveniently located near downtown Evanston and Northwestern University. Pensiero Ristorante is a North Shore favorite and is located on the Inn's first floor.
Fondue is a fun and interactive dining experience! Discover all the ingredients for a unique dining experience including a relaxed atmosphere, private tables, attentive service, fine wines and signature fondue dinners.
The Millennium Reserve stretches from downtown Chicago to the Indiana border and suburban Park Forest. It encompasses numerous neighborhoods, the Southeast lakefront, and 37 South suburban municipalities. In aggregate, the Reserve includes a collection of over 15,000 acres of open space such as trails, wetlands, and forest preserves; Making it ideal for runners, bikers and kayakers alike.
Magnificent, 1,700-acre museum of trees and plants from around the world. Hiking trails, paved roads, restaurant, gift shop, open-air tram and handicapped accessible facilities.
The Museum of Contemporary Photography
Exhibitions and presentations of contemporary photography are supported by grants from the City of Chicago Department of Cultural Affairs/Gallery 37, the Illinois Arts Council and the National Endowment of the Arts. See these works at the museum located at Columbia College.
Nursery specializing in Native & Ornamental Perennials & grasses since 1953.
CITY:St. Charles
One of the best kept secrets in casual dining! The Nest Bar & Grill at Bolingbrook Golf Club can accommodate over 100 guests.
Restaurant specializes in fresh pasta and seafood.
CITY:Burr Ridge
This 850-passenger ship offers lunch and dinner cruises, plus weekend Moonlight and Sunday Jazz Brunch cruises, with live entertainment and amazing city views.
Superb food in a casual, contemporary atmosphere. Outdoor smoke house for great meats and one of Fox Valley's best outdoor dining patios.
CITY:St. Charles
The Old House New House Home Show
Update, renovate and refresh home surroundings with 300 award-winning contractors, select remodelers and creative craftsmen. See the latest in kitchens, baths, basements, additions, landscaping and improvements, Enjoy inspiring daily workshops.
CITY:St. Charles
The Old House New House Home Show
Update, renovate & remodel home surroundings with The Old House New House Home Show. See the latest in home improvements and explore exhibits from 300 select experts. Enjoy inspiring, idea-sparking daily workshops. A portion of the ticket proceeds benefits The Habitat for Humanity.
CITY:St. Charles
The first Middle Eastern Restaurant of its kind and caliber in the area. Our food is prepared fresh daily. Offering specialties such as tabouleh, fattoush, Jerusalem, Lebanese, Mediterranean and chicken salad. We pride ourselves on our tremendous following amongst healthy eaters including many vegetarian dishes.
A specialty food store featuring artisanal, small batch extra virgin olive oils on tap, a variety of balsamic vinegars from Modena, Italy, fresh spices from our spice locker, and a full menu of gourmet food items and accessories. Stop in for a taste and see why customers say wow!
CITY:Long Grove
The Other Mozart by Sylvia Milo at Fermilab
Little Matchstick Factory's The Other Mozart is the true and untold story of Nannerl Mozart, the sister of Amadeus - a prodigy, keyboard virtuoso and composer, who performed throughout Europe with her brother, to equal acclaim, but her work and her story faded away, lost to history. Created by Sylvia Milo, the monodrama is set in a stunning 18-foot dress (and based on facts, stories and lines pulled directly from the Mozart family's humorous and heartbreaking letters. With the opulent beauty of the dress and hair design, the sweet smell of perfume, and the clouds of dusting powder rising from the stage, the performance creates a multi-sensual experience and transports the audience into a world of outsized beauty and delight -- but also of overwhelming restrictions and prejudice. There, in communion with the audience, this other Mozart at last tells her story.
Gifts, collectibles, fine furniture and accessories. Coffee and treats.
CITY:South Elgin
Located inside the Swissôtel Chicago, The Palm is a mainstay on the Chicago Social Scene. In a town known for its steak, The Palm has more than held its own, being named one of the "Top Steakhouses" in Chicago by Chicago magazine.
The Palm Court at the Drake Hotel
Award-winning Executive Chef Baasim Zafar and team serve homemade scones, delectable pastries and tea sweets prepared in house daily, reflecting locally sourced ingredients to ensure an authentically memorable experience. From the original blend of "Palm Court" tea created specifically for The Drake Hotel to the china and sterling silver service with the enchanting ambiance of the live harpist in the background, afternoon tea is truly a memorable experience for all.
We take great pride in using only the finest quality ingredients that are preservative and filler-free, and freshly-prepared the old-fashioned way. We never cut corners! Our famous Barbecue Ribs and Rotisserie Chicken are always cooked fresh throughout the day, and our signature smoked meats – sliced Beef Brisket, Pulled Pork, and Pulled Turkey – are seasoned and slow-cooked for hours. We make our own soups from scratch daily and we even grind and patty our own hamburgers. The way we do things may require extra effort, but we believe you can really taste the difference! For over 35 years, we continue to follow the same philosophy – quality, value, exceptional service and delicious barbecue!
The Patio Restaurant - Bridgeview
Voted "Best BBQ Ribs in the Southland." The Patio is a casual dining, catering and carryout tradition in the Southwest and Western suburbs.
The Patio Restaurant - Orland Park
The Patio is now a 38-year casual dining, catering and carryout BBQ tradition in the Southwest and Western suburbs.
CITY:Orland Park
The Peninsula Chicago is a Five Star, Five Diamond luxury hotel perfectly situated in the heart of the Magnificent Mile. Well-appointed guest rooms—among the largest in Chicago—are complemented with exemplary service and indulgent amenities that include a large indoor swimming pool, modern gym, an outdoor sun deck with city views and exquisite onsite dining. Guests can also retreat to the Peninsula Spa, rated the "#1 Hotel Spa in the U.S." by Condé Nast Traveler.
The Peninsula Spa is the most exclusive and intimate fitness club and spa in the Windy City. Located on the top floor of the hotel, the spa is host to streaming natural light, a half Olympic-length pool and a world-class fitness center.
When you think about Chicago you think Improv Comedy. And when Chicago improvisers think improv they think The Playground Theater. The Playground is the Chicago Improvisers improv theater. This performer run comedy club features the best in Chicago improv and sketch comedy. With shows 7 nights a week, The Playground is a perfect place to start your night with a friends and a laugh.
For your shopping needs, including stores such as Carson Pirie Scott and Circuit City.
CITY:Evergreen Park
Have lunch at The Plaza at Park Grill in Millennium Park, the city's largest outdoor dining venue. Enjoy live music and a sweeping city vista. In the winter, the dining patio is converted into an ice rink, as featured in The Weather Man and Derailed.
The Paderewski and Kosciuszko memorial rooms, folk art, photos and documents all tell the fascinating history of the Polish immigration to America and Chicago, where the largest Polish population outside of Warsaw resides.
Mainstreet shopping & dining destination anchored by Ikea, Macy's and Bass Pro Shops. Ted's Montana Grill, Gordon Biersch and Johnny Rockets are a sampling of the restaurants. Barnes & Noble, H & M, Coldwater Creek and Coach represent the many retailers.
The Promontory is a stylish, two-story bar and restaurant that also houses live music throughout the week. Come for drinks and enjoy an extensive list of wine, cocktails and beer, or browse the menu for unique entrees, small plates, pastries, and more. The Chef de Cuisine and Sommelier team also hosts a tasting every Tuesday featuring a 5-course tasting menu complete with wine pairings.
An homage to beer, pork and oysters, The Publican's eclectic menu is inspired by simple farmhouse fare in a space evocative of a European beer hall. Executive Chef Paul Kahan and Chef de Cuisine Brian Huston have developed a network of purveyors to supply the restaurant with hand-selected, sustainably-harvested fish and seafood as well as sustainably-raised heirloom pork to anchor a rustic menu of simple, eclectic fare. The extensive international beer list, developed by partners Eduard Seitan and Terry Alexander, features 100 or so ales, lagers, stouts and ciders by the bottle, 12 of those available on tap. The Publican is a design partnership from the James Beard Award-winning team of Thomas Schlesser and partner Donnie Madia.
The Pullman State Historic Site - The Factory Complex
The site preserves surviving portions of the industrial complex developed in the early 1880s by George M. Pullman to build luxury railroad passenger cars. The plant was the centerpiece of a company-owned town planned under Pullman's direction.
Chicago's premier piano bar offering top entertainers playing your favorite standards, rock and pop hits; upbeat, comfortable and open late.
The Renaissance Chicago O'Hare Suites Hotel
Located near O'Hare Airport, the Renaissance offers roomy suites with bedroom and living areas. The hotel also features an indoor pool and fitness center. Roll the dice at the new Rivers Casino nearby.
The Reserve at Harrah's Joliet Casino
A steak this good is, well, rare. At our Steakhouse, The Reserve, you find sizzling new dining options like Trio Crusted Filet, in addition to spectacular steaks and pasta dishes. Pair them with a fine wine and savory side dish for a spectacular evening.
The Richard H. Driehaus Gallery of Stained Glass at Navy Pier
The Richard H. Driehaus Gallery of Stained Glass, located near the tip of Chicago's Navy Pier, immerses visitors in darkened rooms bathed in the glow of 11 of Tiffany Studios' stained glass windows, ranging from ecclesiastical to secular landscapes. Each displays the ways Tiffany Studios reinvented tradition, using embedded colors and new types of glass to create folds, ripples, and other textures that gave life to each scene.
The Richard H. Driehaus Museum
The Richard H. Driehaus Museum immerses visitors in one of the grandest residential buildings of 19th-century Chicago, the Gilded Age home of banker Samuel Mayo Nickerson. Philanthropist Richard H. Driehaus founded the museum on April 1, 2003 with a vision to influence today's built environment by preserving and promoting architecture and design of the past.
Set atop Water Tower Place, above prestigious North Michigan Avenue, this property is just an elevator ride from over 100 shops & boutiques and offers exceptional Lake Michigan and skyline views from each spacious guestroom. Recently opened, The dec Rooftop Bar provides a new and chic outdoor spot for sipping, savoring and socializing. Casual elegance and brasserie-inspired cuisine come together at deca RESTAURANT + BAR, serving inventive fare from morning to night. Enjoy easy access to such famed attractions as The Magnificent Mile, The Museum of Contemporary Art and The John Hancock Observatory or stay in and request an in-room visit from the popular Candy Man.
84 rooms 16 suites High-Speed internet access, iron, dryer, coffeemaker, one restaurant. Lounge, valet/laundry, business center, exercise facilities, room service, concierge desk. Free chilled purified water.
Located in Chicago's historic Uptown theater district, at the intersection of Racine, Broadway and Lawrence the Riviera Theatre is a central part of the Chicago's past and present. The Riviera has hosted many of the world's greatest performers and entertainers throughout the years and is also available for private functions. Its grand design and beauty make it a perfect location for a variety of events.
A unique showroom located in the eclectic Oak Park Arts District featuring exclusive fashions for children, specializing in christening outfits, flower girl dresses, boy's tuxedos and First Holy Communion apparel. You will also find a full line of accessories, gifts and Kidorable rain gear. Our knowledgeable staff will make it easy for you to find the perfect outfit for that special day. Hours are by appointment in our showroom, or you can choose to have a free consultation in your home.
CITY:Oak Park
John Wellborn Root designed the Rookery in 1885-9, which reflects the development of new structural systems for large urban buildings during that time. It holds one of the most spectacular interior spaces in the state, an elaborate main lobby and light court that were renovated by Frank Lloyd Wright (1867-1959) in 1905. The Rookery was named a Chicago Landmark in 1972, listed to the National Register in 1970, and named a National Historic Landmark in 1975.
This legendary Italian restaurant is filled with local flavor. The Chicago Tribune and Suntimes gives Rosebud a 3 1/2 star rating and was singled out as one of 15 best pasta restaurants in America.
The Second City - Chicago Mainstage
The Second City opened its doors on a snowy Chicago night in December of 1959, and has since grown to become the world's premier comedy club, theatre and school of improvisation. The Second City has launched the careers of John Belushi, Mike Myers, Tina Fey, Bill Murray, Stephen Colbert, Steve Carell and many others.
The Second City - Donny's Skybox Theater
Donny's Skybox Theatre and the de Maat Studio Theatre are dedicated to presenting productions that are rooted in the crafts of theatrical improvisation and sketch comedy as taught by The Second City Training Center. Alumni, faculty, students, and other members of the extended Second City family unite to develop new voices and points-of-view in a manner that honors the history of the work and seeks to propel it into the future. Donny's Skybox is a studio environment where both emerging and established artists are encouraged to experiment, innovate, and grow.
The Second City - e.t.c. Theater
The Second City opened its doors on a snowy Chicago night in December of 1959, and has since grown to become the world's premier comedy club, theatre and school of improvisation. The Second City has launched the careers of John Belushi, Mike Myers, Tina Fey, Bill Murray, Stephen Colbert, Steve Carell and many others. Dinner/show packages available. Call or log on for specific show information.
The Second City's de Maat Studio Theater
Named for the late improvising guru Martin de Maat, this 49-seat theater is dedicated to presenting productions that are rooted in the crafts of theatrical improvisation and sketch comedy as taught by The Second City Training Center.
A remarkable collection of 70 distinctive shops and restaurants including Bloomingdale's, Gucci, MaxMara and Michael Kors.
Chicago's newest shopping destination features 50 world-class specialty shops. 15 sumptuous restaurants, five elegant hotels, one magnificent Nordstrom and over 2,500 parking spaces.
The Signature Room at the 95th
Enchanted dining experiences await guests at this contemporary American restaurant. Located atop the John Hancock Center, it offers the best view of the city of Chicago. Live jazz, elegant dark wood and marble tiled artdeco interior compliments the mood.
Enjoy hockey, figure skating or recreational skating at this ice arena in Skokie.
The SoFo Tap is your neighborhood bar South of Foster, located at the corner of Clark and Argyle. Enjoy a game of darts, hang out in our spacious outdoor patio, play your favorite song on the jukebox or check out the videos on our flat panel TVs. Our friendly staff is here, ready to pour your favorite drink.
The Spa at Four Seasons Hotel Chicago
The Spa at Four Seasons Hotel Chicago provides a soothing escape in which to relax and rejuvenate in Chicago's Gold Coast. Experience innovative spa treatments that combine natural ingredients with the nurturing care of our expert therapists. Private spa treatment rooms are soundproofed for peace and privacy and include massage rooms, a wet treatment room, an aesthetics room and a manicure/pedicure suite.
The Spa at Trump offers a soothing selection of signature treatments that heal through precious gem-infused oils and renowned products that include Kate Somerville Skincare. Experiences can be customized to the needs of each guest.


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Most of us have spent at least a little time working in jobs we weren't thrilled about. For me, it peaked with McDonald's (no offense, Ronald).
For Trevin Wax, it was Cracker Barrel:
I never wanted to work at Cracker Barrel. I had business experience as an office manager, plus five years of international missions experience tucked under my belt.
But none of that mattered when the most pressing question was, How will you provide for your wife and son this week? Like many before and after me, I did whatever was necessary.
In the past, I've referred to such work as "needs-based" — an adjective that would seem highly redundant to most of our ancestors, not to mention plenty of today's poor. Our now-widespread discussions and contemplations about vocation and personal calling are somewhat new, and we should be careful to recognize why exactly we have the reactions we do about working at reliable, air-conditioned joints like Cracker Barrel.
Each new wave of economic progress and individual empowerment has brought more opportunity to look upward and onward, beyond meeting our own needs and toward something bigger and brighter and so on. This is a marvelous thing, but with such opportunity and privilege also comes a temptation to look inward when it's convenient — to rejoice in ourselves when we succeed and get grumpy when we wind up sniffing grease at Cracker Barrel.
Wax, however, looks back on his experience as much more than a pay-the-bills moment. Rather, the 18 months he spent at Cracker Barrel serves as "a reminder of the Lord's faithfulness to us during a difficult, sometimes frustrating, season of life." Pointing out that "there are hidden blessings in unwelcome work," Wax proceeds to offer four reminders for those who find themselves in work situations that don't seem to fit the mission. (more…)


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American Express Leverages Access and Innovative Tools to Increase Sponsorship Value
August 22, 2012
David Eisenberg, senior manager, Global Sponsorship Marketing, American Express, discussed the evolution and implementation of the company's new tools for sponsorship activation.
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Stocks Slump as Fed Sees 'Downside Risk'
NEW YORK ( TheStreet) -- Stocks closed near session lows on Wednesday after Federal Reserve policymakers said U.S. unemployment remains "elevated" and that "fiscal policy is restraining economic growth," adding that they are prepared to increase or reduce asset purchases as needed.
The S&P 500 dropped 0.93% to 1,582.70. The Dow Jones Industrial Average lost 0.94% to 14,700.95, while the Nasdaq slid 0.89% to 3,299.13.
"The Committee is prepared to increase or reduce the pace of its purchases to maintain appropriate policy accommodation as the outlook for the labor market or inflation changes."
The FOMC indicated it will continue its bond purchasing program, buying mortgage-backed securities at a pace of $40 billion per month in addition to longer-term Treasury securities at a pace of $45 billion a month. The Fed committee affirmed its target federal funds rate at 0% to 0.25%, noting that inflation has been running somewhat below the Committee's longer-run objective while longer-term inflation expectations have remained stable. The Committee anticipated that inflation over the medium term likely will run at or below its 2% objective.
The European Central Bank's rate announcement is scheduled for Thursday. Most economists in a Thomson Reuters poll are expecting a cut of 25 basis points to a new record low of 0.5%.
The latest employment numbers pointed to a slowdown in the economy with payroll processor ADP reporting that the private sector added 119,000 jobs in April vs. a downwardly-revised 131,000 in March. The number was below the consensus estimate of 150,000, according to Thomson Reuters .
Similarly, the ISM Manufacturing Index dipped to 50.7 in April from 51.3 in March, falling further than the 50.9 economists, on average, were expecting, according to Thomson Reuters. The construction spending number for March was also a disappointment, falling 1.7%, compared with forecasts for a 0.7% rise, and following an upwardly-revised increase of 1.5%.
As the biggest decliner in the S&P, Allergan
ADT Corp.
"The company's mix of newly installed systems continues to shift toward more ADT-owned systems, increasing deferred revenue and reducing current period installation revenue," ADT said in a statement.


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It's almost Halloween, everyone. Get excited! Raise the roof! Shake what your mama gave you! OK, maybe not. But seriously. These crafty Halloween ideas will have you positively shrieking with excitement.
And you'll see personalized content just for you whenever you click the My Feed .
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Next Day and Saturday Delivery Available
Goldfren K5-LX102 Pair of Competition Brake Pads For Enduro, Trails & Motocross The K5-LX sintered compound is optimal for striving pro level off-road racers who demand great braking performance and pad life. It is recommended for off-road riders who are looking for a competitive edge and great stopping powerThe K5-LX series is designed for low abrasive interaction with the rotor, long life and self-cleaning capabilities necessary for off-road riding conditions. Additionally, the K5-LX rear brake pads feature a stainless-steel heat shield for thermal isolationFriction materials contain metal-ceramic with a very sophisticated bronze-graphite and a full-metal formulation with fine friction particles to achieve optimal friction properties
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9 Common Email Marketing Mistakes and How to Avoid Them
May 4, 2011
Greg Cangiolosi, CEO, Blue Sky Factory, Inc., discussed the nine email marketing mistakes that many marketers are making, and suggested tactical ways to improve on each critical area of campaign planning and execution.
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Limited Edition
Eyelash Lace Wrap
Style: 570099003
Out of Stock
Sublimely soft and exquisitely embellished, this short knit robe is easy to love. Contrasting trim, relaxed kimono sleeves and floral lace with delicate fringe make it absolutely dreamy.
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- 90% polyester, 10% spandex. Machine wash. Imported.
- From our luxuriously soft Oh My Gorgeous Collection.
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Average Ratings:
"Absolutely Pleased!"
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Debates of April 20th, 2010
House of Commons Hansard #29 of the 40th Parliament, 3rd Session. (The original version is on Parliament's site.) The word of the day was nation.
- Question Period
- Committees of the House
- Royal Canadian Mounted Police Act
- Petitions
- Questions on the Order Paper
- Questions Passed as Orders for Returns
- Business of Supply
- Business of the House
- Business of Supply
- Auditor General of Canada
- National Victims of Crime Awareness Week
- Snowmobiling Ultimate Rider
- Millennium Summit
- G8 and G20 Summits
- Police Officers
- Reel Student Productions
- Multiple Sclerosis
- National Volunteer Week
- Vaisakhi
- Stephen Turner
- Victims of Crime
- Victoria Harbour
- National Volunteer Week
- École secondaire Pierre-Dupuy
- Juno Awards
- Firearms Registry
- Ethics
- Transportation
- Ethics
- Grant Forest Products
- Ethics
- Financial Institutions
- Afghanistan
- Health
- Firearms Registry
- Information Technology
- Public Safety
- Arts and Culture
- Fisheries
- Northern Development
- Agriculture and Agri-Food
- Justice
- Public Safety
- Status of Women
- Automotive Industry
- Taxation
- Information Technology
- Broadband Canada Program
- National Volunteer Week
- Business of Supply
- Criminal Code
Oral Questions
2:50 p.m.
Gail Shea Minister of Fisheries and Oceans
Mr. Speaker, as the hon. member knows, crab has a four-year cycle. Normally, it would go down in intervening years and peak in the fourth year.
As I said before, conservation is our number one priority in the Department of Fisheries and Oceans. That is why the quota is what it is, to protect the future of this fishery.
Northern Development
Oral Questions
2:50 p.m.
Dennis Bevington Western Arctic, NT
Mr. Speaker, today the Auditor General revealed that the main problem with the environmental regulatory regime in the Northwest Territories is the government's own failure to properly implement it.
The Auditor General detailed how the government has starved identified funding needs, not acted on past recommendations and dragged its feet when it comes to implementation.
However, the current government says the system's problems are all the fault of the process created by northerners to protect their lands and waters.
Will the minister admit that the highly publicized objective of regulatory reform is designed to open the north to uncontrolled exploitation and that it, not northerners, has created the problem?
Northern Development
Oral Questions
2:50 p.m.
Chilliwack—Fraser Canyon
Chuck Strahl Minister of Indian Affairs and Northern Development
Mr. Speaker, I encourage the hon. member to get home and talk to some of the industry folks in his own territory, because they are telling me that, if we do not get the regulatory regime fixed by the time the diamond mines are closed, there will not be any more employment
Mind, he is an NDPer and he does not really care about that, but we do. That is why we created the Canadian Northern Economic Development Agency. That is why we have invested in initiatives on community-based environmental monitoring. We have gone ahead and are going to create the first Canadian high Arctic research station.
We continue to invest in the north. That is what northerners deserve and that is what this government expects.
Agriculture and Agri-Food
Oral Questions
April 20th, 2010 / 2:50 p.m.
Alex Atamanenko British Columbia Southern Interior, BC
Mr. Speaker, instead of firing off cheap shots, the minister might want to get out and actually do some work to help people in the north.
Farmers and consumers agree that public scientific research is required to solve problems of debilitating crop diseases, like wheat rust and soya bean root rot. The Auditor General blamed the government's funding cuts of 20% and 6% over the past three years for reducing the amount of peer-reviewed research that helps producers. Cuts to peer-reviewed research mean harm to farmers' incomes and threats to food security across Canada.
Will the minister commit today to reversing cuts to agricultural research funding?
Agriculture and Agri-Food
Oral Questions
2:50 p.m.
Pierre Lemieux Parliamentary Secretary to the Minister of Agriculture
Mr. Speaker, we accept the Auditor General's recommendations, and we are already implementing many of them.
Our government continues to invest in research, including $158 million for the agri-innovations program, turning new ideas in technologies into viable market opportunities, and $26 million to modernize federal laboratories.
We are investing directly in industry, including $28 million for canola, flax and pulse crops, $6 million for beef producers and $10 million for dairy.
Oral Questions
2:55 p.m.
Dona Cadman Surrey North, BC
Mr. Speaker, our government has already done a great deal for victims of crime in this country.
We created the federal ombudsman for victims of crime as well as provided the funding necessary for programs and services for victims across the country. However, we need to do more.
Could the Minister of Justice please inform the House of the legislative step he took today to put the rights of victims ahead of the rights of criminals?
Oral Questions
2:55 p.m.
Niagara Falls
Rob Nicholson Minister of Justice and Attorney General of Canada
Mr. Speaker, I am proud to say that within the last hour, we introduced a bill in the Senate that, once and for all, would get rid of the faint hope clause from the Criminal Code. This is good news for victims and good news for everyone who believes murderers must serve serious time for serious crime.
I call on all members of the House to support this important legislation. After all, a minority Parliament is no excuse not to stand up for victims and law-abiding Canadians.
Public Safety
Oral Questions
2:55 p.m.
Siobhan Coady St. John's South—Mount Pearl, NL
Mr. Speaker, the Auditor General's report shows that the RCMP believes the Conservative government's negligence "increases the risk to police and public safety that could lead to injury or death".
Why has the Conservative government placed front-line officers and Canadian families at unnecessary risk?
Public Safety
Oral Questions
2:55 p.m.
Vic Toews Minister of Public Safety
Mr. Speaker, our government has done more for ensuring that there are officers on the street, as opposed to making cuts as the prior Liberal government did when it in fact shut down Depot, so that there were no officers being trained.
We are in fact concerned about the RCMP. Our funding to provide cadets and technical support for the RCMP is unsurpassed, certainly unsurpassed by the prior government.
Status of Women
Oral Questions
2:55 p.m.
Nicole Demers Laval, QC
Mr. Speaker, the former minister for Status of Women promised the Conseil d'intervention pour l'accès des femmes au travail, a group working to increase women's access to jobs, that it would receive funding from Status of Women Canada's community fund. However, the group was denied funding.
When the Prime Minister distanced himself from his minister, did he do the same with the promises she made?
Status of Women
Oral Questions
2:55 p.m.
Edmonton—Spruce Grove
Rona Ambrose Minister of Public Works and Government Services and Minister for Status of Women
Mr. Speaker, I know this organization does good work in the area of pay equity.
Let me just say how proud I am of the work this government has done to ensure we have successful women in the public service. In fact, we are proud to have elevated intelligent and competent women in the public service.
When it comes to pay equity, more than half of the public service is now made up of women and 43% of the deputy ministers who lead the public service are women.
We will continue to support women, and we will continue to push the envelope to make sure women reach their full potential in public life.
Automotive Industry
Oral Questions
2:55 p.m.
Brian Masse Windsor West, ON
Mr. Speaker, the government is still failing to stand up for Canadians.
The U.S. transportation secretary just levied the largest fine against Toyota for knowing about brake problems months in advance. It was $16 million for "putting consumers at risk" and failing to come clean about a pedal defect it has known about for months.
Here in Canada, we have learned that Toyota executives have secretly known about acceleration problems for at least five years.
When will the minister take action and stop the second-class treatment of Canadians?
Automotive Industry
Oral Questions
2:55 p.m.
Ottawa West—Nepean
John Baird Minister of Transport
Mr. Speaker, let me very clear. The Government of Canada will work to ensure that all legal measures and the full force of Canadian law are used and that all measures are taken to ensure that Canadians are safe. The issue that the member discusses is under investigation by my department.
Let me tell the member opposite about a key difference between Canada and the United States. In Canada ministers of the Crown do not order criminal charges to be laid.
Oral Questions
2:55 p.m.
Bruce Stanton Simcoe North, ON
Mr. Speaker, while our Conservative government is working to create jobs for Canadians, the opposition is finding ways to hike taxes and do more reckless spending. For example, the Bloc, supported by the Liberals and NDP, are pushing Bill C-288 that, according to the PBO, would cost over $.5 billion a year. The bill is set for third and final reading and cannot be amended.
Could the Minister of Finance please inform the House of some of the other problems with this bill?
Oral Questions
3 p.m.
Jim Flaherty Minister of Finance
Mr. Speaker, let us be clear. Bill C-288 would grant a temporary special tax subsidy for new graduates taking employment in so-called depressed regions. How are they defined in the bill? They are so poorly defined in the bill that Fort McMurray would qualify as a depressed region according to Bill C-288.
I know the Bloc leader has personal investments that he is fond of in the oil sands, but this is going too far, subsidizing Fort McMurray through a private member's bill.


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Long-Term Efficacy and Safety Extension Study of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)
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Mucopolysaccharidosis IV A
Morquio A Syndrome
Drug: BMN 110 - Weekly
Drug: BMN 110 - Every Other Week
Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Double Blind (Subject, Caregiver, Investigator, Outcomes Assessor)
Primary Purpose: Treatment
|Official Title:
|A Multicenter, Multinational, Extension Study to Evaluate the Long-Term Efficacy and Safety of BMN 110 in Patients With Mucopolysaccharidosis IVA (Morquio A Syndrome)
- Primary Long-Term Safety/Efficacy Evaluation [ Time Frame: Approximately 240 weeks ] [ Designated as safety issue: Yes ]To evaluate the long-term safety and efficacy of BMN 110 administration at 2.0 mg/kg/qw and 2.0 mg/kg/qow in patients with MPS IVA. Safety results will be determined by numbers and severity of adverse events as well as descriptive statistic analysis of other safety related assessments. Efficacy will be assessed by changes from baseline in 6-minute walk test and 3-minute stair climb test as well as urine keratan sulfate (normalized to urine creatinine.)
- Long-Term evaluation of changes in biochemical markers of inflammation and bone and cartilage metabolism [ Time Frame: Approximately 240 weeks ] [ Designated as safety issue: Yes ]To evaluate the long-term effect of BMN 110 administration at 2.0 mg/kg/qw and 2.0 mg/kg/qow on changes in biochemical markers of inflammation and bone and cartilage metabolism, in patients with MPS IVA.
|Study Start Date:
|July 2011
|Study Completion Date:
|December 2016
|Primary Completion Date:
|June 2016 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: BMN 110 Weekly
BMN 110 Weekly: In Part 1, patients will receive an intravenous infusion of BMN 110 at a dose of 2.0 mg/kg administered over a period of approximately 4 hours once a week.
Drug: BMN 110 - Weekly
In Part 1, patients will receive intravenous (IV) infusions of study drug at a dose of 2.0 mg/kg/qw administered over a period of approximately 4 hours once a week.
In Part 2, patients will continue to receive 2.0 mg/kg of BMN 110 every week, with no placebo.
Other Names:
Experimental: BMN 110 Every Other Week
BMN 110 Every Other Week: In Part 1, patients will receive an intravenous infusion of BMN 110 at a dose of 2.0 mg/kg administered over a period of approximately 4 hours every other week and will receive infusions of placebo on alternating weeks.
Drug: BMN 110 - Every Other Week
In Part 1, patients will receive intravenous (IV) infusions of study drug at a dose of 2.0 mg/kg administered over a period of approximately 4 hours every other week. Patients randomized to the 2.0 mg/kg/qow arm will receive infusions of placebo on alternating weeks, to mask active drug weeks.
In Part 2, patients will receive 2.0 mg/kg of BMN 110 every week, with no placebo.
Other Names:
Detailed Description:
This is a multi-center, multinational, extension study to evaluate 2 dose regimens of BMN 110 treatment in patients with MPS IVA who completed MOR-004.
The last study visit assessments for MOR-004 will constitute Baseline for this study. The first study drug dose of this protocol will occur on Week 0 of MOR-005, which is the same as the last visit (Week 24) of MOR-004. Initially, the study will be double-blind with patients previously randomized to BMN 110 in MOR-004 remaining on their assigned BMN 110 dose regimen (qw or qow dosing). The MOR-004 placebo patients will be re-randomized (1:1 ratio) to one of the 2 BMN 110 dose regimen groups: 2.0 mg/kg/qw or 2.0 mg/kg/qow.
There will be two study parts:
- Part 1 - randomized double-blind until the optimal BMN 110 dose regimen has been determined, based on the final primary efficacy analysis from MOR-004
- Part 2 - open-label BMN 110 treatment with the single optimal dose regimen
|Ages Eligible for Study:
|5 Years and older (Child, Adult, Senior)
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Must have completed MOR-004
- Is willing and able to provide written, signed informed consent. Or in the case of patients under the age of 18 (or other age as defined by regional law or regulation), provide written assent (if required) and have written informed consent, signed by a legally authorize representative, after the nature of the study has been explained, and prior to performance of research-related procedures.
- If sexually active, must be willing to use an acceptable method of contraception while participating in the study.
- If female, of childbearing potential, must have a negative pregnancy test at Baseline and be willing to have additional pregnancy tests done during the study.
Exclusion Criteria:
- Is pregnant or breastfeeding, at Baseline, or planning to become pregnant (self or partner) at any time during the study.
- Has used any investigational product (other than BMN 110 in MOR-004), or investigational medical device, within 30 days prior to Baseline; or is required to use any investigational agent prior to completion of all scheduled study assessments.
- Was enrolled in a previous BMN 110 study, other than MOR-004.
- Has a concurrent disease or condition, including but not limited to, symptomatic cervical spine instability, clinically significant spinal cord compression, or severe cardiac disease that would interfere with study participation, or pose a safety risk, as determined by the Investigator.
- Has any condition that, in the view of the Investigator, places the patient at high risk of poor treatment compliance or of not completing the study.
Please refer to this study by its ClinicalTrials.gov identifier: NCT01415427
Show 41 Study Locations
|Study Director:
|Matthew Mealiffe, M.D.
|BioMarin Pharmaceutical
|Responsible Party:
|BioMarin Pharmaceutical
|ClinicalTrials.gov Identifier:
|NCT01415427 History of Changes
|Other Study ID Numbers:
|Study First Received:
|August 8, 2011
|Last Updated:
|December 19, 2016
|Health Authority:
|United States: Food and Drug Administration
United States: Institutional Review Board
United Kingdom: Medicines and Healthcare Products Regulatory Agency
United Kingdom: Research Ethics Committee
Netherlands: Medical Ethics Review Committee (METC)
Netherlands: The Central Committee on Research Involving Human Subjects (CCMO)
France: Afssaps - Agence française de sécurité sanitaire des produits de santé (Saint-Denis)
France: Conseil National de l'Ordre des Médecins
Canada: Health Canada
Korea: Food and Drug Administration
Taiwan : Food and Drug Administration
Taiwan: Department of Health
Italy: The Italian Medicines Agency
Italy: Ethics Committee
Argentina: Ministry of Health
Argentina: Administracion Nacional de Medicamentos, Alimentos y Tecnologia Medica
Denmark: Ethics Committee
Denmark: Danish Health and Medicines Authority
Japan: Institutional Review Board
Japan: Pharmaceuticals and Medical Devices Agency
Portugal: Ethics Committee for Clinical Research
Portugal: INFARMED, National Authority of Medicines and Health Products, IP
Brazil: Ethics Committee
Brazil: National Health Surveillance Agency
Brazil: National Committee of Ethics in Research
Colombia: INVIMA Instituto Nacional de Vigilancia de Medicamentos y Alimentos
Colombia: Institutional Review Board
Germany: Ethics Commission
Germany: Federal Institute for Drugs and Medical Devices
Qatar: Hamad Medical Corporation
Saudi Arabia: Ethics Committee
Saudi Arabia: Saudi Food and Drug Authority
Spain: Agencia Española de Medicamentos y Productos Sanitarios
Spain: Comité Ético de Investigación Clínica
Norway: Norwegian Medicines Agency
Keywords provided by BioMarin Pharmaceutical:
Mucopolysaccharidosis IV type A
Mucopolysaccharidosis IVA
MPS IV Type A
Morquio A Syndrome
Lysosomal Storage Disorder
N-acetylgalactosamine-6-sulfate sulfatase
enzyme replacement therapy
Additional relevant MeSH terms:
Mucopolysaccharidosis IV
Pathologic Processes
Carbohydrate Metabolism, Inborn Errors
Metabolism, Inborn Errors
Genetic Diseases, Inborn
Lysosomal Storage Diseases
Connective Tissue Diseases
Metabolic Diseases
Bone Diseases, Developmental
Bone Diseases
Musculoskeletal Diseases
ClinicalTrials.gov processed this record on January 14, 2017