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Separate But Not Equal?Posted by Frank J. Oteri in Contemporary Classical Music, Music History
A lot of folks in the New York City classical music community were very upset last week over a list published in Time Out New York magazine of the fifty greatest New York musicians of all time. Each was honored with a photo, a brief description of their contribution to music history and a recommended CD.
Not a single person cited on the list was someone who worked primarily in classical music. Sure, John Zorn, Duke Ellington, and John Cale (the Velvet Underground was TONY's number one pick) all wrote symphonic works, but those were never mentioned anywhere. That said, the list was full of variety and arcana: everyone from Broadway diva Barbara Streisand to free jazz tenor saxophonist Albert Ayler to salsa vocalist Hector LaVoe (although salseros know that his most enduring contributions to the genre were the result of frontman/trombonist Willie Colón's work).
A similar list a few months back in Time Magazine made my blood boil even more. To me, lists like these reveal the mainstream media's total cluelessless when it comes to classical music. It's not just innocent ignorance: the folks who spin such news perpetuate the myth that classical music is dead and not at all a part of contemporary life. To Time Out's credit, they published a letter by NYC Opera dramaturg Cori Ellison expressing disappointment that Time Out's list could ignore New Yorkers like George Gershwin, Aaron Copland, Maria Callas, and Beverly Sills. That said, a close reading of TONY Music Editor Mike Wolf's response is revelatory. (Bold emphasis below is mine.)
"[O]ur primary mistake was in not specifying that classical music artists were, in fact, excluded from consideration for the "50 Greatest" list. We felt we needed to do this partly because classical has its own section in the magazine, but also because Gershwin and many others chiefly proved their greatness off the stage. Measuring the greatness of Public Enemy versus Billie Holiday was some challenge; adding Beverly Sills to the mix would've killed us."
It's somewhat disingenuous to claim classical musicians "chiefly proved their greatness off the stage" in defense of omissions on a list featuring recommended recordings. And indeed, if it would kill adjudicators to consider Sills or Gershwin when faced with applications from Lady Day and P.E., people concerned that it could be the death knell for recognition for contemporary classical music if awards like the Pulitzer and the Grawemeyer were open to all genres of music have good reason to fear. Of course, there are people who understand the bigger musical picture. Time Out's own classical music editor, Steve Smith, is a musical polyglot who could argue the comparative merits of Anthrax, Robert Ashley, Missy Elliott, and Charles Wuorinen. All the more pity that his voice seems conspicuously absent from that list. Or, more importantly, that such a broad view of music really can't be found anywhere. At the end of the day, having a separate section or separate awards for what we do really doesn't allow us to reach out to a wide audience, yet not having our own things would keep the smaller audience who is interested from ever finding out about this stuff.
As the Civil Rights movement showed us two generations ago, separate is not equal; we should not be content with a small corner of the playground whether it's a single page among hundreds in a magazine or a handful of Grammy Awards that we've been exiled from collecting on prime time television. Twenty-five years ago as an undergrad at Columbia, a fellow student expressed shock when I told him that I composed things like sonatas and concertos. "Really? No one's written that kinda stuff for a hundred years." When I described to him the history of classical music in the 20th century, he was incredulous. "Never heard of it. Classical music died with Wagner and then there was big band jazz. Jazz died after World War Two and there's been rock and roll ever since." At the time, I thought he was an idiot. Now I realize that he's merely a byproduct of the American education system who got all his information about cultural history from reading and watching mainstream media. We have the power to reclaim the media by writing and by speaking out.


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Reverse transcription is the synthesis of single-stranded DNA (complementary DNA, or cDNA) using single-stranded RNA as a template, mediated by reverse transcriptases (RTs). The cDNA can be used as a template for amplification by PCR or to generate a cDNA library.
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subset: commoncrawl


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We all know now that obesity in the United States is considered to be an epidemic, and is also on the rise. A recent article in the New York Times outlines some of the more shocking statistics our country faces if these trends continue as they have been since the 1970s.
By 2020, three of every four Americans will be overweight or obese if the trends continue. By 2030, there could be 65 million more obese adults in the United States than in 2010, according to the epidemiologist Dr. Y. Claire Wang and her colleagues at Columbia University's Mailman School of Public Health.
If these predictions actually come true, it would mean 8 million more cases of diabetics, 6.8 million more cases of atherosclerotic heart disease and stroke and more than 500,000 more cases of cancer. Obviously, this would also impact health costs in our country.
Camp Shane weight loss camps for children and Shane Diet & Fitness Resorts weight loss program for adults are doing their part to fight obesity by helping people learn a healthy lifestyle and maintain it through nutritious eating and physical activity. For more information about transforming your life, visit www.campshane.com and www.shanedietresorts.com.


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Marijuana-infused food products selling quickly
Marijuana products are selling so quickly, one store ran out of marijuana-laced food products. In most cases, the edibles have a higher potency than smoking marijuana.
The Greener Side in Pueblo County sold out of its marijuana infused-food projects for recreational users on Saturday. All they have left are more potent edibles reserved for medical customers.
Hank Borunda, the owner of The Greener Side, said eating a candy containing 100 milligrams of THC, the active chemical in pot, is the equivalent of smoking two joints.
"When you take an edible, it goes throughout your body. It's a relaxation. It's pure chill pretty much," said Joshua Borjon, a bud tender.
A medical marijuana customer, who asked to only be referred by his first name Sean, said, " I use it specifically to take care of the arthritis in the lower half of my body. I use it because I also have just regular trouble sleeping."
The store sells edibles in the form of lollipops, sweet and sour drops and peppermint candy. Some medical marijuana users consider edibles to be medicine.
"The main people that really come in here for edibles are the people that are in pain," Borjon said. "The people that want to be discreet about it and people that don't like the whole act of smoking."
Sean said it's part of the cure for treating his arthritis.
Borunda expects to be stocked up on edibles later this week. On average, an edible cost $15-$20 for a recreational user.


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by Anton Shilov
Patriot Memory on Wednesday followed its rival Kingston Memory with monstrous USB flash drive with 128GB capacity, which is higher than the capacity of solid-state drives in many notebooks.
Patriot Extreme Performance Xporter Magnum can boast not only with unprecedented capacity of 128GB, which is equal to 14 – 15 dual-layer DVD movies, but also with 210x read speed, or equivalent of 31MB/s data transfer rate. With such read speed, it will take more than an hour to completely unload the 128GB USB drive and, considering that writing takes longer than reading, even more time it will take to record data onto the unit.
"Patriot is elated to bring the consumer a product that is unprecedented in the market. The Magnum gives the consumer unequaled storage flexibility to make video libraries. Even in this age of Blu-Ray movies, you can store at least 14 titles and with the incredible speeds for read and write, the capabilities for storage and compiling information are endless," said Meng Jay, Patriot's Product Manager.
Even though both Patriot and Kingston promote their 128GB drives for data carrying, it is more than likely that the vast majority of consumers will simply archive their data on such USB drives.
Unlike its rival, Patriot did not reveal whether the units will be build to order only. Besides, the company also did not announce the price, which may be around $500.


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jimmy339 wrote:I'm looking for a tea that is sweet whereas I don't have to add as much sugar. Any recommendations? Preferably green or white tea since I read that it has the best antioxidants.
Andy wrote:Most of the green teas, and all the white teas I've tried are sweet without sugar. Even some low quality bulk tea, and Temple of Heaven pearl tea I pulled out of teabags are fairly sweet. Although even the sweetest green tea can become bitter if brewed wrong. http://chineseteas101.com/brewingmethod.htm Gaiwan brewing is supposed to be the best for green tea.
By the way, it's worth getting used to tea without sugar. It just makes the experience so much better, especially for green, white, and oolong teas. You'll probably be surprised by what you've been missing by putting sugar in tea. Although it may take some time to get used to it without sugar before noticing those subtle differences.


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- 2 Chronicles 7:14 RSV
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"We as Catholics have not properly combated (the culture) because we have not been taught our Catholic Faith, especially in the depth needed to address these grave evils of our time. This is a failure of catechesis both of children and young people that has been going on for fifty years. It is being addressed, but it needs much more radical attention... What has also contributed greatly to the situation is an exaltation of the virtue of tolerance which is falsely seen as the virtue which governs all other virtues. In other words, we should tolerate other people in their immoral actions to the extent that we seem also to accept the moral wrong. Tolerance is a virtue, but it is certainly not the principal virtue; the principal virtue is charity... Charity means speaking the truth. I have encountered it (not speaking the truth) many times myself as a priest and bishop. It is something we simply need to address. There is far too much silence — people do not want to talk about it because the topic is not 'politically correct.' But we cannot be silent any longer."
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Joseph Ratzinger - The Feast of Faith"In those situations where homosexual unions have been legally recognized or have been given the legal status and rights belonging to marriage, clear and emphatic opposition is a duty. ... If all Catholics are obliged to oppose the legal recognition of homosexual unions, Catholic politicians are obliged to do so in a particular way, in keeping with their responsibility as politicians." CDF 2003
One of the most dangerous errors is that civilization is automatically bound to increase and spread. The lesson of history is the opposite; civilization is a rarity, attained with difficulty and easily lost. The normal state of humanity is barbarism, just as the normal surface of the planet is salt water. Land looms large in our imagination and civilization in history books, only because sea and savagery are to us less interesting. — C. S. Lewis
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Grant unto thy Church, we beseech Thee, O merciful God, that She, being gathered together by the Holy Ghost, may be in no wise troubled by attack from her foes. O God, who by sin art offended and by penance pacified, mercifully regard the prayers of Thy people making supplication unto Thee,and turn away the scourges of Thine anger which we deserve for our sins. Almighty and Everlasting God, in whose Hand are the power and the government of every realm: look down upon and help the Christian people that the heathen nations who trust in the fierceness of their own might may be crushed by the power of thine Arm. Through our Lord Jesus Christ, Thy Son, who liveth and reigneth with Thee in the unity of the Holy Ghost, God, world without end. R. Amen.
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"The legalization of the termination of pregnancy is none other than the authorization given to an adult, with the approval of an established law, to take the lives of children yet unborn and thus incapable of defending themselves. It is difficult to imagine a more unjust situation, and it is very difficult to speak of obsession in a matter such as this, where we are dealing with a fundamental imperative of every good conscience — the defense of the right to life of an innocent and defenseless human being."
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"One of the most dangerous errors is that civilization is automatically bound to increase and spread. The lesson of history is the opposite; civilization is a rarity, attained with difficulty and easily lost. The normal state of humanity is barbarism, just as the normal surface of the planet is salt water. Land looms large in our imagination and civilization in history books, only because sea and savagery are to us less interesting."
- C.S. Lewis
More food for thought:
"I expect to die in bed, my successor will die in prison and his successor will die a martyr in the public square. His successor will pick up the shards of a ruined society and slowly help rebuild civilization, as the church has done so often in human history."
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St. Gregory Nazianzus ep. 131 - AD 382"We will conquer your Rome, break your crosses, and enslave your women. If we do not reach that time, then our children and grandchildren will reach it, and they will sell your sons as slaves at the slave market."
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Roman Sunday Supper
For lunch I was at the college refectory of a friend. We spent the afternoon talking about today's heretics. Tonight I am out alone at a great pizza place. I'll graze and read on my Kindle. For a starter: Tonight's … Continue reading
Posted in On the road, What Fr. Z is up to Tagged Isola della Pizza, Nepi, pizza, restaurants, Rome 13 Comments


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The Wayland Mission Center, in partnership with Baptist churches, associations, agencies, conventions, the global Baptist community, and the greater faith community, serves as a rallying point to encourage, educate, empower, equip, and inspire students and west Texas churches to be the presence of Christ throughout the world.
This vision statement of the Wayland Mission Center, adopted on October 15, 2009, articulates the purpose and motivation of this now seven-year-old movement. We have stated seven goals for the WMC:
Scripture serves as the foundation of all that we do in following the leadership of God's Spirit at WMC:
After this I looked and there before me was a great multitude that no one could count, from every nation, tribe, people and language, standing before the throne and in front of the Lamb. They were wearing white robes and were holding palm branches in their hands. And they cried out in a loud voice, "Salvation belongs to our God, who sits on the throne, and to the Lamb" (Revelation 7:9-10).
Then Jesus came to them and said, "All authority in heaven and on earth has been given to me. Therefore go and make disciples of all nations, baptizing them in the name of the Father and of the Son and of the Holy spirit, and teaching them to obey everything I have commanded you. And surely I am with you always, to the very end of the age" (Matthew 28:18-20).


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Interpersonal Violence (IV) in Society
It is important to note that various forms of interpersonal violence have made themselves prevalent in society.
Examples where Interpersonal Violence can be seen include:
- Videogames
- Films
- Music
- TV shows
- Advertisements
- Commercials
- News
Why is Interpersonal Violence in Society Detrimental?
- Rape Culture sets the tone that violent acts towards people are socially acceptable.
- It decreases the prevalence of upstanders, because people are reinforced by society to not intervene.
- Rape Culture is everywhere in the media and becomes a model of acceptable behavior.
- It becomes normalized for people who witness Rape Culture to stand by when they hear or see Rape Culture. They participate in the bystander effect by passing by instead of intervening.
To gain knowledge on how to combat IV in Society visit our IVP UP-Stander page.


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Corneal ulcers in cats are an erosion of the various layers which make up the outer protective surface of the cat's eye called the cornea. When an ulcer develops, it can be very serious because part of the inside of the cat's eye is now exposed.
Most commonly, corneal ulcers are caused by some sort of trauma to the eye. This may be a blunt impact, or possibly a scratch from another animal. In somewhat rarer cases, a chemical infection may trigger the ulcer - such as if the cats gets shampoo or some other irritant in its eye. Finally, ulcers may also be caused by bacterial infections or viral infections such as feline herpes, according to VCA Animal Hospitals.
Corneal ulcers are very painful, so owners will likely notice the issue when the cat begins squinting or pawing at its eye. The eye may also take on a cloudy appearance as the ulcer begins to develop. The cat may also keep its eye shut or blink repeatedly.
It's important owners bring their cats to a veterinary clinic as soon as possible if a corneal ulcer is suspected. In many cases, ulcers can be treated with medication if caught early enough. However, an ulcer that erodes through all protective layers to the eyeball itself may irreparably damage the eye and cause blindness.


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FC Bayern Munchen 2004 home red shirt.Features open collar in white with embroidered team crest,logo and screened on sponsor in front.Clim Lite fabric that keeps comfortable and mesh panels on each side.100% polyester.
Soccerplus first opened in 1994. We were one of the first soccer websites to hit the webView more
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Phone: 1-800-945-7291
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Office of International Student Services
Welcome to Regent University, your home away from home! Approximately 130 international students representing about 50 nations attend Regent through on-campus and online programs. The Office of International Student Services (OISS) understands and appreciates the unique needs of our international students and helps meet those needs by providing specialized services with a caring approach. If you are a current or a newly admitted F-1 international student, this site will provide you with helpful information on a variety of adjustment and immigration topics. We look forward to serving you and welcoming you to our communtiy!
Prospective Students/Applicants: For questions about admission or I-20 issuance please contact the International Admissions Office at email@example.com or call Graduate Admissions at 757.352.4936 or Undergraduate Admissions at 757.352.4846. Click here for more information on international admissions.
"The OISS is an indispensible Office to all International Students coming to Regent University, from the first stages of helping us to prepare to attend Regent University while still in our home countries, through our program of studies, to returning to our Home Countries." -Regent International Student


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HASTINGS, Minn. (AP) — A Minnesota judge has dismissed charges against the former head of a national right-to-die group accused in the death of an Apple Valley woman.
Judge Karen Asphaug ruled Minnesota's law against advising suicide is unconstitutionally overbroad. She dismissed charges against Thomas Goodwin, former president of Final Exit Network.
Last year, four members of the group were charged in the 2007 death of Doreen Dunn, who killed herself in her home. Prosecutors said the defendants provided Dunn with information and support to follow through with her suicide.
Final Exit members claim they do not encourage suicide, but that the act of giving information and emotional support could be interpreted as "encouraging" under Minnesota's assisted-suicide law. They claim the law is unconstitutional because it violates a person's right to freedom of speech.
Copyright 2013 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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For spring break this year, we went to Port Aransas, Texas, which is on the barrier island east of Corpus Christi. Fortunately, it was after the big spring break rush, when the normally quiet town of about 3,500 was swamped with over 100,000 partiers. While there were some visitors there at the same time, the beach was never close to crowded and the town was mellow. After spending time there, I concluded that the Gulf Coast of Texas is a great place, though it was not my first choice of destinations.
I'm typically not a beach town kind of person, but I had a good time in Port Aransas. The weather is great, people are friendly and everything is very, very unpretentious. It's also very affordable. While it's probably a lot busier during the high seasons, going in the shoulder season (fall and spring break, with the exception of spring break week) is a good way to go. The weather is still great, you have your choice of places to stay, and there's plenty of space on the beach.
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ciri-ciri hewan berdarah panas


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A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas (Protocol 102)
Recruitment status was: Active, not recruiting
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Treatment Overview
This phase II study will evaluate the activity of sirolimus in children and adults with NF1 and inoperable plexiform neurofibromas that have the potential to cause significant morbidity. The following disease strata will be studied:
Stratum 1: Progressive plexiform neurofibroma(s) that have the potential to cause significant morbidity. The endpoint will be time to tumor progression based on volumetric tumor measurements.
Stratum 2: Plexiform neurofibromas without documented radiographic progression at trial entry. The endpoint will be radiographic response. As of May 2009, Stratum 2 was closed to enrollment. Stratum 1 is active.
Neurofibromatosis Type 1
Drug: Sirolimus, Rapamycin
Phase 2
|Study Type:
|Study Design:
|Intervention Model: Single Group Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|A Phase II Study of the mTOR Inhibitor Sirolimus in Neurofibromatosis Type 1 Related Plexiform Neurofibromas
- Increased time to disease progression based on volumetric MRI [ Time Frame: 24 weeks Stratum 1 / 48 weeks Stratum 2 ]
- feasibility and toxicity [ Time Frame: same as above ]
|Study Start Date:
|April 2008
|Estimated Study Completion Date:
|August 2014
|Estimated Primary Completion Date:
|August 2014 (Final data collection date for primary outcome measure)
|Assigned Interventions
Experimental: 1
Drug: Sirolimus, Rapamycin
This phase II study will evaluate children and adults with neurofibromatosis type-1 (NF1) and plexiform neurofibromas treated with sirolimus. It is divided in two strata. The first stratum will evaluate time to progression (TTP) in children and adults with NF1 and progressive plexiform neurofibromas with the potential to cause significant morbidity treated with sirolimus. The second stratum will evaluate objective radiographic response to sirolimus in children and adults with NF1 and inoperable plexiform neurofibromas with the potential to cause significant morbidity that do not have documented progression of the PN at time of trial entry.
Other Name: Sirolimus, Rapamune, Rapamycin
Show Detailed Description
|Ages Eligible for Study:
|3 Years to 75 Years (Child, Adult, Senior)
|Sexes Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria: all patients (stratum 1 and 2):
- All patients must have the clinical diagnosis of NF1 using the NIH Consensus Conference criteria.
- Six or more café-au-lait spots (greater than or equal to 0.5 cm in prepubertal subjects or greater than or equal to 1.5 cm in postpubertal subjects).
- Freckling in the axilla or groin.
- Optic glioma.
- Two or more Lisch nodules.
- A distinctive bony lesion (dysplasia of the sphenoid bone or dysplasia or thinning of long bone cortex).
- A first-degree relative with NF1.
- Patients must have plexiform neurofibroma(s) that have the potential to cause significant morbidity, such as (but not limited to) head and neck lesions that could compromise the airway or great vessels, brachial or lumbar plexus lesions that could cause nerve compression and loss of function, lesions that could result in major deformity (e.g., orbital lesions) or significant cosmetic problems, lesions of the extremity that cause limb hypertrophy or loss of function, and painful lesions. Patients with paraspinal plexiform neurofibromas will be eligible for this trial. Histologic confirmation of tumor is not necessary in the presence of consistent clinical and radiographic findings, but should be considered if malignant degeneration of a plexiform neurofibroma is clinically suspected.
- Age: Patients must be greater than or equal to 3 years of age at the time of study entry.
- Durable Power of Attorney: Adults evaluated for this study will be offered a durable power of attorney. Adults who are unable to provide informed consent will have to have a durable power of attorney in order to participate in this trial.
- Disease status: Measurable disease: Patients must have measurable plexiform neurofibroma(s) amenable to volumetric MRI analysis. For the purpose of this study, a measurable lesion will be defined as a lesion of at least 3 cm measured in one dimension.
- Performance Level: Karnofsky greater than or equal to 50% for patients > 10 years of age and Lansky greater than or equal to 50 for patients less than or equal to 10 years of age (Appendix IV). Note: Patients who are unable to walk because of paralysis, but who are up in a wheelchair, will be considered ambulatory for the purpose of assessing the performance score.
- Prior Therapy: Patients who underwent surgery for a progressive plexiform neurofibroma will be eligible to enter the study after the surgery, provided the plexiform neurofibroma was incompletely resected and is measurable. Patients are only eligible if complete resection of a plexiform neurofibroma with acceptable morbidity is not feasible, or if a patient with surgical option refuses surgery. Patients may have been previously treated for a plexiform neurofibroma but must have fully recovered from the acute toxic effects of all prior chemotherapy or radiotherapy prior to entering this study.
- a. Myelosuppressive chemotherapy: Must not have received within 4 weeks of entry onto this study.
- b. Hematopoietic growth factors: At least 7 days since the completion of therapy with a growth factor that supports platelet, red or white cell number or function.
- c. Biologic (anti-neoplastic agent): At least 14 days since the completion of therapy with a biologic agent. For agents that have known adverse events occurring beyond 14 days after administration, this period must be extended beyond the time during which adverse events are known to occur. These patients must be discussed with the Study Chair on a case-by-case basis.
- d. Investigational Drugs: Patients must not have received an investigational drug within 4 weeks.
- e. Steroids: Patients with endocrine deficiencies are allowed to receive physiologic or stress doses of steroids if necessary.
- f. CYP3A4 inhibitors: Patients may not be currently receiving strong inhibitors of CYP3A4, and may not have received these medications within 1 week of entry. These include: Macrolide Antibiotics: clarithromycin, telithromycin, erythromycin, troleandomycin; Gastrointestinal prokinetic agents: cisapride, metoclopramide; Antifungals: itraconazole, ketoconazole, fluconazole, voriconazole, clotrimazole; Calcium channel blockers: verapamil, diltiazem, nicardipine; and, Other drugs: rifampin, bromocriptine, cimetidine, danazol, cyclosporine oral solution.
- Grapefruit juice.
- g. CYP3A4 inducers: Patients must also avoid strong inducers of CYP3A4 and may not have received these medications within 1 week of entry. These include: Anticonvulsants: carbamazepine, phenobarbital, phenytoin; Antibiotics: rifabutin, rifapentine; Herbal preparations: St. John's wort (Hypericum perforatum, hypericine).
- h. Enzyme inducing anticonvulsants : Patients may not be taking enzyme - inducing anticonvulsants, and may not have received these medications within 1 week of entry, as these patients may experience different drug disposition. These medications include: Carbamazepine (Tegretol), Felbamate (Felbtol), Phenobarbitol, Phenytoin (Dilantin), Primidone (Mysoline), Oxcarbazepine (Trileptal), and, Herbal preparations: St. John's wort (Hypericum perforatum, hypericine).
- i. XRT: Greater than or equal to 6 months from involved field radiation to index plexiform neurofibroma(s); greater than or equal to 6 weeks must have elapsed if patient has received radiation to areas outside index plexiform neurofibroma(s).
- j. Surgery: At least 2 weeks since undergoing any major surgery.
- Organ Function Requirements; Adequate Bone Marrow Function Defined as: Peripheral absolute neutrophil count (ANC)greater than or equal to 1500/μL; Platelet count greater than or equal to 100,000/μL (transfusion independent); and Hemoglobin greater than or equal to 10.0 gm/dL (may receive RBC transfusions).
- Adequate Renal Function Defined as: A serum creatinine based on age, OR a creatinine clearance or radioisotope GFR greater than or equal to 70ml/min/1.73 m2
- Adequate Liver Function Defined As: Bilirubin (sum of conjugated + unconjugated) < or equal to 1.5 x upper limit of normal (ULN) for age, and SGPT (ALT)< or equal to 5 x upper limit of normal (ULN) for age, and Serum albumin > or equal to 2 g/dL.
- Fasting LDL Cholesterol: Patients must have a fasting LDL cholesterol of < 160 mg/dL; Patients taking a cholesterol lowering agent must be on a single medication and on a stable dose for at least 4 weeks
Specific eligibility criteria stratum 1 Disease status:
- Patients must have a progressive plexiform neurofibroma(s). Progression at the time of study entry is defined as: Presence of new plexiform neurofibromas on MRI or CT, OR A measurable increase of the plexiform neurofibroma (> or equal to 20% increase in the volume, or a > or equal to 13% increase in the product of the two longest perpendicular diameters, or a > or equal to 6% increase in the longest diameter) over the last two consecutive scans (MRI or CT), or over the time period of approximately one year prior to evaluation for this study.
Specific eligibility criteria stratum 2 Disease status:
- Radiographic disease progression as defined in Section 4.2.1 is not required for trial entry.
Exclusion Criteria:(Both Strata):
- Chronic treatment with systemic steroids or another immunosuppressive agent.
- Patients with endocrine deficiencies are allowed to receive physiologic or stress doses of steroids if necessary.
- Evidence of an active optic glioma, malignant glioma, malignant peripheral nerve sheath tumor, or other cancer requiring treatment with chemotherapy or radiation therapy. Patients not requiring treatment are eligible for this protocol.
- Dental braces or prosthesis that interfere with volumetric analysis of the neurofibroma(s).
- Other concurrent severe and/or uncontrolled medical disease which could compromise participation in the study (e.g. uncontrolled diabetes, uncontrolled hypertension, severe infection, severe malnutrition, chronic liver or renal disease, active upper GI tract ulceration).
- A known history of HIV seropositivity or known immunodeficiency. HIV testing will not be required as part of this trial, unless HIV is clinically suspected.
- Impairment of gastrointestinal function or gastrointestinal disease that may significantly alter the absorption of sirolimus (e.g. ulcerative disease, uncontrolled nausea, vomiting, diarrhea, malabsorption syndrome or small bowel resection). A nasogastric tube (NG tube) is allowed.
- Women who are pregnant or breast feeding.
- Males or females of reproductive potential may not participate unless they have agreed to use an effective contraceptive method during the period they are receiving the study drug and for 3 months thereafter. Abstinence is an acceptable method of birth control. Women of childbearing potential will be given a pregnancy test within 7 days prior to administration of sirolimus and must have a negative urine or serum pregnancy test.
- Patients who have received prior treatment with an mTOR inhibitor.
- History of noncompliance to medical regimens.
- Patients unwilling to or unable to comply with the protocol, or who in the opinion of the investigator may not be able to comply with the safety monitoring requirements of the study.
- Patients who have an uncontrolled infection.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00634270
|United States, Alabama
|The University of Alabama at Birmingham
|Birmingham, Alabama, United States, 35294
|United States, District of Columbia
|Children's National Medical Center
|Washington, District of Columbia, United States, 20010
|United States, Illinois
|University of Chicago
|Chicago, Illinois, United States, 60637
|United States, Maryland
|National Cancer Institute (NCI)
|Bethesda, Maryland, United States, 20892
|United States, Massachusetts
|Children's Hospital Boston
|Boston, Massachusetts, United States, 02115
|United States, Missouri
|Washington University
|St. Louis, Missouri, United States, 63110
|United States, Ohio
|Cincinnati Children's Hospital Medical Center
|Cincinnati, Ohio, United States, 45229-4006
|United States, Pennsylvania
|Children's Hospital of Philadelphia
|Philadelphia, Pennsylvania, United States, 19096
|United States, Utah
|University of Utah
|Salt Lake City, Utah, United States, 84132
|Principal Investigator:
|Bruce Korf, MD
|The University of Alabama at Birmingham
|Principal Investigator:
|Brian Weiss, MD
|Children's Hospital Medical Center, Cincinnati
|Study Director:
|Roger Packer, MD
|Children's National Medical Center - Chairman of the NF Consortium
|Responsible Party:
|University of Alabama at Birmingham
|ClinicalTrials.gov Identifier:
|NCT00634270 History of Changes
|Other Study ID Numbers:
|Study First Received:
|February 20, 2008
|Last Updated:
|March 14, 2014
Keywords provided by University of Alabama at Birmingham:
Plexiform, Neurofibromatosis Type 1, Sirolimus, Phase II
Additional relevant MeSH terms:
Neurofibromatosis 1
Nerve Sheath Neoplasms
Neurofibroma, Plexiform
Neoplasms, Nerve Tissue
Neoplasms by Histologic Type
Neoplastic Syndromes, Hereditary
Neurocutaneous Syndromes
Nervous System Diseases
Heredodegenerative Disorders, Nervous System
Neurodegenerative Diseases
Genetic Diseases, Inborn
Peripheral Nervous System Neoplasms
Nervous System Neoplasms
Peripheral Nervous System Diseases
Neuromuscular Diseases
Anti-Bacterial Agents
Anti-Infective Agents
Antibiotics, Antineoplastic
Antineoplastic Agents
Antifungal Agents
Immunosuppressive Agents
Immunologic Factors
Physiological Effects of Drugs
ClinicalTrials.gov processed this record on January 23, 2017


text:
I hadn't heard that NBC was down on Conan. But I wouldn't mind if this happens:
NBC cans Conan.
Dave moves to 10:00 slot.
CBS picks up Conan for 11:30 slot.
CBS ends up with Dave, Conan, and Craig and I don't have to mess with the remote.
I hadn't heard that NBC was down on Conan. But I wouldn't mind if this happens:
NBC cans Conan.
Dave moves to 10:00 slot.
CBS picks up Conan for 11:30 slot.
CBS ends up with Dave, Conan, and Craig and I don't have to mess with the remote.
"Now that's a real shame when folks be throwin' away a perfectly good white boy like that."
The problem isn't Leno or Conan -- the problem is that both shows have the exact same format. Monologue, skit, celebrity interview, skit / second guest, credits. Even if both shows are well done, the viewer is going to get tired of watching the same thing twice in one night.
If Leno was doing more of a variety show, it might work -- but his format is essentially unchanged from his Tonight Show days. Either he has to change or Conan has to change because there isn't room for two of them on the same network, plus Dave and the late-nighter (Fallon & Ferguson). It's too much.
Cincinnati Here We Go.
26 Years and Counting...
I think more then likely they will let Leno go and he'll end up somewhere else with an 11:30 show.
Go Gators!
Exactly. I'm not saying it's right. Lord knows Leno had his problems when he first started and there were some execs at NBC who were ready to pull the plug on him. But he survived and eventually thrived. The easy solution - if they percieve there's a problem - is that they boot Conan and pay him off then drop Leno back into his old spot. He's a known quantity and he's more mainstream than Conan. The thing you need to know about Leno is that he craves work. When he did stand up he was on the road nearly every night in one club or another. He certainly didn't take a lot of vacations when he was on the Tonight Show. If they cancel his show, he isn't going to be happy to just get paid off.
Leno was #1 for close to 15 years. He was at the top of his game, and now they have this muddled mess that makes no sense.
Not sure how you fix this....
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text:
I love this cards
Everyone's favourite penguin surf harmony group sing a fun birthday song for you.
Send these beautiful flowers e-card wishing lots of love, smiles and blessings. . .
Say Happy Birthday to someone special... A CAPPELLA! IF YOU WANT TO LEARN THIS SONG...
Send this colorful and exciting ecard with jazzy upbeat music to the birthday girl or guy!
Cakes and candles to wish your special one a very happy birthday.
Send these beautiful flowers to your near and dear ones on their birthday.
Send across a cute teddy bear to give a tight birthday hug to your dear ones.
Send this cute greeting to your friends and family to wish them happy birthday.
Send a sparkling birthday wish to your dear ones.
A beautiful birthday ecard with wonderful visual for you to wish your dear/ near ones...
The Muppet Show's Swedish Chef dancing in the kitchen to wish you a happy birthday! No...
Send these beautiful flowers ecard on his/ her birthday.
Send your sincere birthday wishes upon butterfly wings.
Send this cute kitten card to wish a very happy beautiful birthday to all your friends...
Send magical greetings to your near & dear ones on their birthday!
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text:
Running in Sandals?
Our Favorite Things: Locally-made, huarache-style sandals for the trail
Patrick Sweeney runs the Leadville 100 in his Lunas. Photo by Caleb Wilson / Llama Running Company.
Many of us first became familiar with the notion of running in sandals through reading about Mexico's huarache-clad Tarahumara in Christopher McDougall's 2009 bestseller, Born to Run. Those who have embraced huaraches are still a relatively small percentage of the general trail-running population—but you can find them everywhere from your local 5K to 100-milers.
"Depending on terrain, having the option to let your feet breathe and have that near-barefoot experience can really make running way more fun," says Jonathan Loewus-Deitch, one of our huarache testers. "Running in sandals gives variety to your experience and truly makes you focus on how you run and where you're stepping."
Aside from requiring a higher level of attention to the trail, huaraches encourage a low-impact, mid/forefoot strike. Even if you have no interest in ditching your running shoes altogether, huaraches can be a great tool for strengthening the muscles in your feet and improving your running form.
Read on for the dirt on two brands of trail-running huaraches that we've tried out ...


text:
Allergy Research Group, Ox Bile, 500 mg, 100 Veggie Caps
- You earn loyalty credit for every order you place at iHerb!
- Loyalty credit is equal to 5% of the value of your order, excluding shipping charges.
- Your loyalty credit will be applied towards your next order as soon as your current order has shipped.
- Your loyalty credits are valid for up to 60 days from the date of your last purchase.
This product is already in your Wish List.
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Expiration Date:?Jun 2019Expiration Date
The length of time for the expiration date or "best used before" date depends on the type of product, as well as the brand.
Perishable items (such as flax oils or certain probiotics) generally have shorter expiration dates. Although our warehouse is fully air-conditioned, these more fragile items are put in cold storage (freezer or refrigeration unit) for maximum freshness.
Our receiving department does its best to verify and then enter the correct expiration dates for all incoming products. However, discrepancies do occur from time to time. This being said, the exceptionally high turnover at iHerb ensures that our inventory is among the freshest in the industry.
Shipping Weight:?0.24 lbsShipping WeightThe Shipping Weight includes the product, protective packaging material and the actual shipping box. In addition, the Shipping Weight may be adjusted for the Dimensional Weight (e.g. length, width & height) of a package. It is important to note that certain types of products (e.g. glass containers, liquids, fragile, refrigerated or ice packed) will often require protective packaging material. As such, these products will reflect a higher Shipping Weight compared to the unprotected product.
- Product Code: ALG-70850
- UPC Code: 713947708501
- Package Quantity: 100 Veggie Caps
- Dimensions: 2.1 x 2.1 x 3.9 in, 0.2 lbs
- Dietary Supplement
- Hypoallergenic
Ox Bile 500 mg
Derived from a bovine source and freeze-dried (lyophilized) to maintain its biological activity, Ox Bile is a suitable supplement to the liver's production of bile.
Suggested Use
As a dietary supplement, 1 capsule three times daily with meals, or as directed by a healthcare practitioner.
Other Ingredients
Hydroxypropyl methylcellulose, l-leucine.
Keep in a cool, dry place, tightly capped.
California Proposition 65 Warning: Warning. This product contains chemicals known to the State of California to cause birth defects or other reproductive harm.
|Supplement Facts
|Serving Size: 1 Capsule
|Servings Per Container: 100
|Amount Per Serving
|% Daily Value
|Bile (Bovine)
|500 mg
|* Daily Value not established.


text:
A friend in boston and I are having a long-distance disagreement about what tea is "better" puerh or matcha. (Naturally, this is a stupid argument, drink both ymmv, but we like to argue)
Well we have both agreed to learn to drink the other's favorite kind of tea "correctly" -- he's getting sample of my favorite puerhs (thus far) and he already has a few nice pots for brewing.
On the other hand I needed to buy a whisk and bowl. So I bought this one
http://cgi.ebay.com/ws/eBayISAPI.dll?Vi ... 0999451791
(I love pink!) Then I realized I ought to have asked for advice first.
Ah well. I'm excited for it to come anyway. He's sending me some "very fresh" matcha. I hope this experiment will work!
now will i need a sifter or something? I'm off to read more about matcha.


text:
Medieval Fishtail Crown Braids
Well with the whole Game of Thrones craze restarted there is no wonder ladies are opting for that untamed and gorgeous medieval look. A great way to achieve this look is with halo and crown braids. Try this look by switching it up with some gorgeous fishtail braids to give it a unique and trendy look.


text:
Also from Raw Story, today:
Priest pushes Obama supporters to confession
By Andrew McLemore A California pastor told his parishioners to attend confessional if they had voted for President-elect Barack Obama because of his stance on abortion, the McClatchy Tribune reported.
The Rev. Joseph Illo, pastor of St. Joseph Catholic Church in Modesto, Calif., said voting for a pro-choice candidate amounted to a punishable sin.
"If you are one of the 54 percent of Catholics who voted for a pro-abortion candidate, you were clear on his position and you knew the gravity of the question, I urge you to go to confession before receiving communion. Don't risk losing your state of grace by receiving sacrilegiously," Illo wrote in a letter dated Nov. 21.
Illo sent the letter to more than 15,000 members of his parish, one of 34 parishes in the Stockton diocese.
Illo also delivered this message in a homily, the Modesto Bee reported.
Many religious leaders warned voters against Obama during the campaign because of his stance on abortion. Earlier this month, U.S. Roman Catholic bishops cautioned Obama against enacting an "evil law" that would deregulate the "abortion industry", saying it would alienate millions of Americans and sow disunity, Agence France Presse reported.
I hope the Catholic Brass are stupid enough for this to gain momentum. Many parishioners in the US will tell the church to fuck off, and probably a number of them will leave (though I think they're more likely to go "rogue" than to actually leave). Religious rifts that develop out of resistance to dogmatism are good though, regardless.
from the article: saying it would alienate millions of Americans and sow disunity
Oh my oh my, the raw irony… the catholic church, the largest proponent of monotheism with their triple-headed, guilt-giving god monster threatening alienation and disunity amongst the masses. One has to wonder if father Illo (why does he go by reverend if he's catholic?) is calling for confessions so he can compile a list of "sinners" for future reference…
I do hope the congregates see through this twaddle.
It seems that voting for Obama is yet one more sin I am guilty of. My family will never be able to buy me out of Purgatory.
I either want a tax deduction for my donations to Obama, or the Catholic Church to start paying taxes.
I either want a tax deduction for my donations to Obama, or the Catholic Church to start paying taxes.
I think the first thing the Catholic church should do is return all the cash to the Jews that the nazis funneled through their church bank, from the stolen artifacts, during WWII. Then they can go about turning over all those pedophile priests they shipped to other parishes to the authorities.
Then they can go about turning over all those pedophile priests they shipped to other parishes to the authorities.
...or to the parents…


text:
Miss Me mixes casual with glamorous! This Miss Me top features an attractive scoop neckline. Silver-tone beads and metallic foil prints decorate wing screen print on front. Tee is made of 60% cotton/40% polyester. Imported. S(2-4), M(6-8), L(10-12).
Missing dyes and shades are characteristic of this garment and not considered a defect.


text:
Hector's dolphin
Hector's dolphin (Cephalorhynchus hectori) is the best-known of the four dolphins in the genus Cephalorhynchus and is found only in New Zealand. At about 1.4 m in length, it is one of the smallest cetaceans, and New Zealand's only endemic cetacean.
Hector's dolphin was named after Sir James Hector (1834–1907). He was the curator of the Colonial Museum in Wellington (now the Museum of New Zealand Te Papa Tongarewa). He examined the first specimen found of the dolphin. The species was scientifically described by Belgian zoologist Pierre-Joseph van Beneden in 1881.
Maui's dolphin (Cephalorhynchus hectori maui) is a subspecies of Hector's dolphin found off the northwest coast of New Zealand's North Island.[2] It is the most endangered subspecies of marine mammal (other cetaceans with a similarly perilous conservation status inhabit rivers and estuaries only). There are approximately 55 Maui's dolphins remaining.
Māori names for Hector's and Maui's dolphin include Tutumairekurai, Tupoupou and Popoto.
|... thirty years ago there were over 26,000 Hector's and Maui's dolphins. Today, due to human activity, there is a struggling population of around 7,270 Hector's dolphins - and Maui's are the rarest marine dolphins in the world with around 110 left - WWF Apr. 2007 [3]
Physical description
Hector's dolphin is the smallest of the delphinids. Mature adults have a total length of 1.2-1.6 m (3.9-5.25 ft) and weigh 40–60 kg.[4] The species is sexually dimorphic, with females being slightly longer and heavier than males. The body shape is stocky, with no discernible beak. The most distinctive feature is the rounded dorsal fin, with a convex trailing edge and undercut rear margin.
The overall appearance is pale grey but closer inspection reveals a complex and elegant combination of colours. The back and sides are predominantly light grey, while the dorsal fin, flippers and flukes are black. The eyes are surrounded by a black mask, which extends forward to the tip of the rostrum and back to the base of the flipper. A subtly shaded, crescent shaped black band crosses the head just behind the blowhole. The throat and belly are creamy white, separated by dark grey bands meeting between the flippers. A white stripe extends from the belly onto each flank below the dorsal fin.
At birth, Hector's dolphin calves have a total length of 60–80 cm and weigh 8–10 kg.[5] Their coloration is the same as adults, although the grey has a darker hue. Four to six vertical pale stripes, caused by fetal folds affecting the pigmentation, are present on the calf's body until an age of about 6 months.
Population and distribution
Hector's dolphins are endemic to the coastal regions of New Zealand. The species has a patchy distribution around the entire South Island, although there are only very occasional sightings in the deep waters of Fiordland. The centres of distribution are on the west coast between Kahurangi Point (41˚S) and Jacksons Bay (44˚S)[6] and on the east coast around Banks Peninsula (43˚S-44˚S).[7] Maui's dolphin is found only on the west coast of New Zealand's North Island between 36˚S and 40˚S, with the majority of animals in the central portion of this range between the Manukau and Raglan Harbours.[8]
Abundance has been estimated from a series of five line-transect surveys between 1998 and 2004. The abundance estimate for South Island Hector's dolphin is 7270 (CV = 16%).[5][6] Current population size is estimated to be 27% of the abundance in 1970 before significant human impacts occurred.[9]
The species has a preference for shallow, coastal waters less than 100 m deep.[10][11] This means they are most commonly seen close to shore, although in shallow regions they have been sighted up to 34 km from the coast. In some areas, there is a pronounced seasonal difference in distribution, with dolphins being sighted further offshore and in deeper water in winter, presumably in response to movements of their prey species.
Ecology and life history
Caught and stranded Hector's dolphins have provided information on the life history and reproductive parameters of the species. The maximum observed age is 19 years for females and 20 years for males.[4] However, a long term photo-ID project at Banks Peninsula has shown that individuals reach at least 23 years of age. Males attain sexual maturity between five and nine years of age, and females have their first calf between seven and nine years old.[4] The calving interval is two to four years.
These life-history characteristics mean that Hector's dolphins, like many other small cetaceans, have a low potential for population growth. Maximum population growth rate has been estimated to be 1.8-4.9% per year, although the lower end of this range is probably more realistic.[12]
Foraging and predation
Hector's dolphins find their food close to shore, generally in groups of two to eight dolphins. They feed at the ocean surface and sea floor, with their diet including ahuru, yellow-eyed mullet, kahawai, arrow squid, herring and red cod.[13]
Hector's dolphins are believed to be generalist feeders, with prey selection based on size rather than species. Stomach contents of dissected dolphins have included surface schooling fish, mid water fish and squid and a wide variety of benthic species.[3] The largest prey item recovered from a Hector's dolphin stomach was an undigested red cod weighing 500 g with a standard length of 35 cm.
Natural predators of Hector's dolphins include sharks and probably orca. Remains of Hector's have been found in sevengill and blue shark stomachs.[14]
Hector's dolphin is covered by the Memorandum of Understanding for the Conservation of Cetaceans and Their Habitats in the Pacific Islands Region (Pacific Cetaceans MOU)
Gillnet threat
Bycatch in bottom-set gillnets has been responsible for the majority of human induced mortality of Hector's dolphins. Gillnets are made from lightweight mono-filament that is undetectable to the dolphins. Hector's dolphins swim into the nets, get caught and subsequently drown. Some dolphins are able to escape from gillnets, as they are spotted displaying scars consistent with entanglement.[15]
The nationwide estimate for bycatch in commercial gillnets is 110-150 dolphins per year[16] which is far in excess of the level which is considered to be sustainable.[17] Hector's dolphins face a range of other impacts including trawl bycatch,[18] tourism,[19][20] pollution[3] and habitat modification.
Conservation management for Hector's dolphin has focussed on reducing gillnet bycatch. The first marine protected area (MPA) for Hector's dolphin was designated in 1988 at Banks Peninsula, where commercial gillnetting was effectively prohibited out to 4 n.mi. (7.4 km) offshore and recreational gillnetting was subject to seasonal restrictions. A second MPA was designated on the west coast of the North Island in 2003. Despite this protection, the Hector's dolphin population was predicted to continue declining due to bycatch outside the MPAs.[8]
On 15 November 2007, the World Wide Fund for Nature launched an online petition asking Helen Clark, New Zealand's Prime Minister at the time, to introduce emergency measures to protect the Hector's and Maui dolphins.[21] New measures were introduced by the Ministry of Fisheries in 2008 effectively banning gillnetting within 4 n.mi. of the majority of the South Island's east and south coasts, regulating gillnetting on the South Island's west coast out to 2 n.mi. (3.7 km) offshore and extending the gillnet ban on the North Island's west coast to 7 n.mi. (13 km) offshore. There are also restrictions on trawling in some of these areas. For further details on these regulations see the Ministry of Fisheries website.[22] Five marine mammal sanctuaries were designated in 2008 to manage non-fishing related threats to Hector's and Maui's dolphin.[23] Their regulations include restrictions on mining and seismic acoustic surveys.
New Zealand free-diver William Trubridge referred to his goal to make the first 100m single breath unassisted dive as "Project Hector" to draw attention to Hector's dolphin. He successfully achieved the dive on December 13, 2010, setting a new world record. [24] A mere three days later Trubridge would surpass his own goal by setting a new world record of 101 meters [25] in a no fins dive on December 16, 2010.
- MNZ MM001915, collected Kaikoura, New Zealand, no date data.
See also
- ^ Reeves, R.R., Dawson, S.M., Jefferson, T.A., Karczmarski, L., Laidre, K., O'Corry-Crowe, G., Rojas-Bracho, L., Secchi, E.R., Slooten, E., Smith, B.D., Wang, J.Y. & Zhou, K. (2008). "Cephalorhynchus hectori". IUCN Red List of Threatened Species. Version 2012.2. International Union for Conservation of Nature. http://www.iucnredlist.org/apps/redlist/details/4162. Retrieved 18 January 2013.
- ^ Baker, A.N., Smith, A.H. and F.B. Pichler. 2002. Geographical variation in Hector's dolphin: recognition of a new subspecies of Cephalorhynchus hectori. Journal of the Royal Society of New Zealand 32: 713-727.
- ^ a b c Jenny Riches. "Hector's and Maui's survival in Kiwi's hands, says WWF". http://www.wwf.org.nz/news/2007/07-04-03-maui.cfm. Retrieved May 11, 2007.[dead link]
- ^ a b c Slooten, E. and Dawson, S.M. 1994. Hector's dolphin Cephalorhynchus hectori. Pp. 311-333 in: Handbook of Marine Mammals. Volume V (Delphinidae and Phocoenidae) (S.H. Ridgway and R. Harrison eds). Academic Press. New York.
- ^ a b Slooten, E. 1991. Age, growth and reproduction in Hector's dolphins. Canadian Journal of Zoology 69: 1689-1700.
- ^ a b Slooten, E., Dawson, S.M. and Rayment, W.J. 2004. Aerial surveys for coastal dolphins: abundance of Hector's dolphins off the South Island West Coast, New Zealand. Marine Mammal Science 20:477-490.
- ^ Dawson, S.M., Slooten, E., DuFresne, S.D., Wade, P. and Clement, D.M. 2004. Small-boat surveys for coastal dolphins: Line-transect surveys of Hector's dolphins (Cephalorhynchus hectori). Fishery Bulletin 102: 441-451.
- ^ a b Slooten, E., Dawson, S.M., Rayment, W. and Childerhouse, S. 2006. A new abundance estimate for Maui's dolphin: What does it mean for managing this critically endangered species? Biological Conservation 128: 576-581.
- ^ Slooten, E. 2007. Conservation management in the face of uncertainty: effectiveness of four options for managing Hector's dolphin bycatch. Endangered Species Research 3: 169-179.
- ^ Bräger, S., Harraway, J. and Manly, B.F.J. 2003. Habitat selection in a coastal dolphin species (Cephalorhynchus hectori). Marine Biology 143: 233-244.
- ^ Rayment, W., Dawson, S. and Slooten, E. In press. Seasonal changes in distribution of Hector's dolphins at Banks Peninsula, New Zealand: implications for protected area design. Aquatic Conservation: Marine and Freshwater Ecosystems. doi:10.1002/aqc.1049.
- ^ Slooten, E. and Lad, F. 1991. Population biology and conservation of Hector's dolphins. Canadian Journal of Zoology 69: 1701-1707.
- ^ Protection of Hector's dolphins around Bank's Peninsula. Department of Conservation. 1988. ISBN [[Special:BookSources/00478010605|00478010605]].
- ^ Banks Peninsula Marine Mammal Sanctuary Technical Report. Department of Conservation. 1992. pp. B-9. ISBN 0-478-01404-X.
- ^ Banks Peninsula Marine Mammal Sanctuary Technical Report. Department of Conservation. 1992. pp. A-29. ISBN 0-478-01404-X.
- ^ Davies, N., Bian, R., Starr, P., Lallemand, P., Gilbert, D. and McKenzie, J. 2008. Risk analysis of Maui's dolphin and Hector's dolphin subpopulations to commercial setnet fishing using a temporal-spatial age-structured model. Ministry of Fisheries, Wellington, New Zealand. 113 p. http://www.fish.govt.nz/NR/rdonlyres/B034115D-247A-42E5-B08F-F5D267046C59/0/HectorNIWAriskanalysis.pdf
- ^ Slooten, E. and Dawson, S.M. 2008. Sustainable levels of human impact for Hector's dolphin. The Open Conservation Biology Journal 2: 37-43.
- ^ Starr, P. and Langley, A. 2000. Inshore Fishery Observer Programme for Hector's dolphins in Pegasus Bay, Canterbury Bight, 1997/1998. Published client report on contract 3020, funded by Conservation Services Levy. Department of Conservation, Wellington. 28p.
- ^ Bejder, L., Dawson, S.M. and Harraway, J.A. 1999. Responses by Hector's dolphins to boats and swimmers in Porpoise Bay, New Zealand. Marine Mammal Science 15: 738-750.
- ^ Stone, G. S. and Yoshinaga, A. 2000. Hector's dolphin (Cephalorhynchus hectori) calf mortalities may indicate new risks from boat traffic and habituation. Pacific Conservation Biology 6: 162-170.
- ^ Tell New Zealand to protect endangered dolphins, World Wildlife Fund Passport Panda website, retrieved 11:10 a.m. Saturday, 15 March 2008.
- ^ "Hector's Dolphins". Ministry of Fisheries. 2008-10-01. http://www.fish.govt.nz/en-nz/Environmental/Hectors+Dolphins/default.htm?WBCMODE=PresentationUnpublished++%23MainContentAnchor%23MainContentAnchor. Retrieved 2010-02-16.
- ^ "Marine mammal sanctuaries: Marine protected areas". Department of Conservation. http://www.doc.govt.nz/conservation/marine-and-coastal/marine-protected-areas/marine-mammal-sanctuaries/. Retrieved 2010-02-16.
- ^ "William Trubridge succeeds at 100m Project Hector". DeeperBlue. http://www.deeperblue.com/newsfull.php/2370/. Retrieved 2010-12-13.
- ^ "Trubridge Delivers 101 Meters CNF". DeeperBlue. http://www.deeperblue.com/newsfull.php/2372/. Retrieved 2010-12-17.
Further reading
- National Audubon Society: Guide to Marine Mammals of the World ISBN 0-375-41141-0
- Encyclopedia of Marine Mammals ISBN 0-12-551340-2
- Whales, Dolphins and Porpoises, Mark Carwardine 1995 ISBN 0-7513-2781-6
- Facts about Maui's dolphin Department of Conservation - Several Images & listed as 'critically endangered' - Retrieved 2007-05-08.
- Hector's Dolphins, New Zealand Ministry of Fisheries - Retrieved 2007-02-09.
- Hector's Dolphin - Factsheet, Royal Forest and Bird Protection Society of New Zealand Inc - Retrieved 2007-02-09.


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Side swept layered hairstyle with fringe
A neat, short crop is turned remarkably stylish and avant-garde by an expert application of colors. A fringe is swept from deep in one side to the other, skimming the eyebrows with tucked-under, layered ends, and ending mid-cheek on the other side. This whole is alternately striped with a brassy strawberry blonde, purple, and red, making for a strikingly colored cap. The uncovered section on one side is buzzed and dyed purple. It is bordered at the back with the continuation of the crop, echoing the color of the fringe.


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August 2, 2010 WIC Update
SUBJECT 1: Food and Formula Reference Guide – FFRG (August 1, 2010 version)
SUBJECT 2: Nutrition Education Opportunity
JOB ANNOUNCEMENT: Two (2) Part Time Breastfeeding Peer Counselors
JOB ANNOUNCEMENT: Nutritionist
- Updated Food and Formula Reference Guide – FFRG (August 1, 2010 version) Important!
The Food and Formula Reference Guide (FFRG) has been updated. Please share the following attachments with your staff:
- Attachment #1 - A List of Changes to FFRG and MOWINS
- Attachment #2 - Updated FFRG (August 1, 2010 version) -- Please see the attachment #1 for the changes. The Table of Contents is hyper-linked with respective page/section and interactive. Two versions of this attachment are provided—one in Adobe Acrobat (.pdf) format and one in Microsoft Word (.doc) format.
If you have any questions and/or suggestions, please feel free to contact Takako Tagami at email@example.com.
- Nutrition Education Opportunity: WIC Registered Dietitians, Nutritionists, Registered Nurses, Certified Nurse Midwives, Nurse Practitioners, Physicians, and other Public Health Professionals who serve pre-conceptual, pregnant, postpartum and breastfeeding women will want to take advantage of this two-day National Maternal Nutrition Intensive Course, shown by videostream on October 14-15, 2010 in Jefferson City. This year's continuing education program focuses on the improvement of maternal and infant health through the delivery of risk-appropriate high-quality nutrition services. This training is presented by the University of Minnesota's School of Public Health and the Missouri Department of Health and Senior Services, Bureau of WIC and Nutrition Services, Nutrition Training Institute. It is also sponsored by the Maternal and Child Health Bureau, Health Resources and Services Administration at the U.S. Department of Health and the Human Services and Food and Nutrition Service at the U.S. Department of Agriculture. Please see the attached registration brochure for details. Contact Michele Bailey at 573-751-6481 or email@example.com, or contact the University of Minnesota at http://www.sph.umn.edu/ce/trainings/coursepage.asp?activityId=9546&stype=2 or http://www.sph.umn.edu/ce/trainings/coursepage.asp?activityId=9545&stype=2 to register for the online course to be held at your location.
2010 University of MN Maternal Nutrition training brochure
List of Changes to FFRG & MOWINS
Food & Formula Reference Guide
Food & Formula Reference Guide
WIC Positions
JOB ANNOUNCEMENT: Two (2) Part Time Breastfeeding Peer Counselors needed to support and encourage WIC breastfeeding moms. Contact with clients by telephone as well as face to face. Counselors will also facilitate group education sessions for prenatal clients and family members about the benefits/advantages of breastfeeding. Work with team members that are enthusiastic about getting our clients to breastfeeding.
Qualifications include: Successful breastfeeding experience for at least 6 months within the last 2 years. High School or GED, some college preferred; working knowledge of computers; experience on "facebook" and texting preferred; good communication, organization and telephone skills. Work 20-24 hours a week; flexible days and times. Apply on-line at www.swopehealth.org. If you have questions about the on-line process, call 816.922.7645 ext 2100. For further information about the position, call Ernestine Persley RD, LD at 816.922.7645 ext 6345 or e-mail email@example.com.
JOB ANNOUNCEMENT: Nutritionist needed- Join our friendly and cohesive WIC team committed to providing excellent customer service, patient-centered counseling and relevant nutrition education one on one and group settings. Develops and documents individual care plans for high risk clients; conducts certifications for eligible clients; promotes breastfeeding activities and education.Minimum qualifications include: Bachelors degree in a nutrition related field with at least 15 semester hours in food and nutrition, including at least one course in diet therapy and one course in community nutrition. College/university program must be ADA approved and supervised. At least one year of experience is preferred. Apply on line at: www.swopehealth.org. If you have questions about the on-line process, call 816.922.7645 ext 2100. For further information about the position, call Ernestine Persley RD, LD at 816.922.7645 ext 6345 or e-mail firstname.lastname@example.com.


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Lost Player Status
Posted 01 December 2012 - 05:26 PM
Please reinstate me back in when possible.
Posted 01 December 2012 - 07:17 PM
Posted 04 December 2012 - 12:56 PM
Same here.
Posted 04 December 2012 - 01:50 PM
Posted 05 December 2012 - 08:12 PM
Same here.
Posted 07 December 2012 - 07:43 PM
Posted 08 December 2012 - 02:39 PM
We will looking into resolving this here sometime soon. No exact time frame has been set yet. Once it is resolved we will notify you and work to correct and rectify this situation. I did not come in here to reply because I thought it was just thought that you all would know we will make this right for you all. But I guess I was wrong.
So please rest assured we will be working to resolve this issue, but we still have users accounts that need to be created and resolved. So we currently feel that is the priority and then we will begin to resolve the issues with the PC members.
I hate to say this but on a real front it may be shortly after the new year before this is rectified since it is very labor intensive to research every PC member and their transaction date and then add them with the new renewal date. We will add time for the time lost, that should go without saying, but let me go ahead and address that as well.
Thank you all for your support and continued understanding during this time.
If you have an issue or would like to say anything in regards to this, please feel free to contact me directly. Since the majority of the blame falls on my shoulders over this issue.
I can be reached at : email@example.com or firstname.lastname@example.com
Once again thank you all for your continued support.
Posted 08 December 2012 - 06:43 PM
Posted 09 December 2012 - 10:24 PM
Posted 10 December 2012 - 01:05 AM
I(we) meant no disrespect and as a players club member(s) and I(we) was just wondering the severity of the situation. I only saw pinned post about fixing peoples post counts and lost accounts. Since it seemed that people who weren't in the players club had priority in fixing their post count seem like a higher priority then people who paid to support the site.
I just wanted to be sure that we weren't forgotten and the best we got was a "we are working on it" I figure since now we got some what a general ideal of the situation it'll help me to get a general ideal of whats going on.
again thank you Willie, I just wanted to know what was going on and did not mean any type of disrespect or rudeness
Edited by Razgriz183, 10 December 2012 - 01:06 AM.
Posted 11 May 2013 - 08:06 PM
Posted 08 June 2013 - 08:39 AM
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Herrera Perfume & Cologne
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Excellent cologne - one of my favorites as it mixes well with my body chemistry. It has a long lasting scent that seems to smell even better as the evening wears on. It is strictly an "adult" scent for evenings and/or casual evenings. I would recommend it highly.
Written by E.S. Cumming on July 14, 2014
I have been wearing Herrera by Carolina Herrera since it was introduced. It is my go to scent. I have tried others but always come back to my favorite. I really can't smell it on myself after the first few minuets so I know that it is not overpowering a room. I get compliments from many people and questions regarding what perfume am I wearing. Friends and family know that this is the perfect gift for me.
Written by Carol's Cats on July 09, 2014
1 - 5 (of 126 Reviews)


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Men's 4x800 Relay Highlights Final Day for Track and Field Teams
Men's 4x800 Relay Highlights Final Day for Track and Field Teams
The Buena Vista indoor track and field teams wrapped up competition at the 2013 Iowa Conference Indoor Track and Field Championships on Sunday afternoon with each team posting its best overall team finish in recent years. The men's 4x800 meter relay team brought home the lone championship title in record-breaking fashion.
Beginning on the women's side, senior Rachel Burnette (Irwin, Iowa/IKM-Manning) got BVU going strong on the final day with her fifth-place effort in the 55 meter hurdles in a career-best clocking of 8.68 seconds. Sophomore Maggie Marker (Clarion, Iowa/Clarion-Goldfield) followed that up with a fourth-place finish in the 55 meter dash, reaching the finish-line in a career-best 7.41 seconds. She just missed out on all-conference accolades by 0.08 seconds.
Marker didn't miss out on earning those accolades, however, in the 200 meter dash, as she took third with a career-best mark of 26.38 seconds. Sophomore Casey James (Lenox, Iowa/Orient-Macksburg) also scored team points for BVU in the event, taking seventh with her personal-best time of 26.67 seconds.
After the 4x800 meter relay team took seventh, the Beavers then added a fourth-place effort to the table in the final race of the championships (4x400 meter relay), posting a time of 4:06.26; a mark that was just over a second out of a top-three performance. The team was made up of Marker, Burnette, Abby Hesnard (Sac City, Iowa/East Sac County) and Laura Eberly (Manning, Iowa/IKM-Manning).
After just missing out on scoring points for the team in the shot put on Saturday, Molly Hutchins (Spirit Lake, Iowa/Spirit Lake) made it into the top-eight on Sunday, capturing eighth in the weight throw with a heave of 12.84 meters (42-1.05).
Overall, BVU tallied 40 points for the championships and took fifth overall in the team race. It's the team's highest finish and most points scored since taking sixth back in 2007 with 50.5 points.
Over on the men's side, the 4x800 meter relay team of Andrew Smith (Brayton Iowa/Exira), Garrett Woodson (Dysart, Iowa/Union), Ben Berberich (Royal, Iowa/Clay Central-Everly), and Seth Woodson (Dysart, Iowa/Union), highlighted the day for the Beavers by winning the race with a new IIAC and school-record time of 7:52.15 seconds. It breaks the previous conference mark of 7:59.59 set back in 2009 and bettered its own mark of 8:03.04 set earlier this season during the BVU Open.
Both Seth and Garrett captured top-five finishes in the 800 meter run with Seth taking third overall in 1:56.17 and Garrett fifth at 1:56.61. Seth's time was one of three times to surpass the facilities previous fastest time in the event of 1:56.20.
Freshman Andrew May (Webster City, Iowa/Webster City) gave the Beavers an eighth-place finish in the 55 meter hurdles. Ryan Eberly (Manning, Iowa/IKM-Manning) ran 51.71 in the 400 meter dash and placed 10th overall, but was less than one second out of the top-three.
The 4x400 meter relay team closed out the championships for the Beavers with a fifth-place effort in 3:29.16.
Nolan Sampson (Cherokee, Iowa/Cherokee) earned the only points for the team in field events, taking fifth in the high jump by clearing his best height of the year at 1.96 meters.
As a team, BVU took seventh and finished with 35 total points. This follows a year in which it was eighth with only 21 points. It marks the team's highest finish since 2009 when it took fifth with 89 points.


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I have gone through that court testimony doc at embeddedgurus.com. It is not only interesting, but can be considered as a lesson if you are in the business of designing safety critical hardware/firmware.
The following is an excerpt from that pdf. It is an answer given by Mr. Barr when asked about how they had access to the toyota source code.
"That experts see source code is not unusual, but the protections around this source code are certainly unusual in my experience. The source code review involves looking at electronic documents on computers. There is basically a room the size of a small hotel room that is disconnected from the Internet, no cell phones allowed inside or would work inside. In that room there is about five computers and some cubicles. In there, it is possible to believe view on the computer screen Toyota's source code. We couldn't take any paper in, take any paper out, couldn't wear belts, watches. There was a guard. It was worse than airport security was on the way here. Each time in and out, even to go to the bathroom."


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Overcast ~
Dense Fog Advisory
Friday, Jan. 20, 2017
Happy CustomerPosted Tuesday, May 22, 2007, at 1:30 PM
I wanted to comment on a recent pleasant bit of customer service I experienced last weekend.
Being an entertainment lover, I often find myself down at the local video rental store to check out the latest video game releases (for either myself or my son, who is also an avid video game player). My family and I headed out to Family Video, where we recently got a membership, to check out what the store had in stock, and since we hadn't gotten familiar with how the store operates yet.
Well, we were the only customers in the store on this particular day, and the store clerk greeted us very friendly as we entered the store and began browsing the aisles. After about 5-10 minutes of scoping the shelves, we noticed that the store was offering discounts for multiple rentals, so we grabbed a couple video games and headed up to the counter to check out.
The friendly store clerk happily scanned the games and also removed the discs, placed them in a computer desktop tower disc drive, where I noticed the young lady clean the discs with a chemical before placing back in the box and giving them to us. (I had never seen staff in a video rental store do this before, and sometimes the discs are loaded with fingerprints, smudges and scratches..) She gave us our discount on the games, and informed us that they have a weekly "featured" new release movie for 75 cents if we were interested.
For 75 cents, when some of these new movie rentals are $4-$5, we grabbed up the movie too. (Stranger Than Fiction with Will Ferrell, we hadn't seen it yet.)
The clerk then told us that we could extend our half-price rental period another 30 days for a nominal fee. (First-time customers, as my family and I were, get half-price rentals for the first 30 days of their membership.) Although we passed on this special for the time being, it's nice to know that you can continue to rent movies and games there for half price for a small fee, which ultimately results in a nice savings on rentals down the road. (Especially for us frequent renters.)
Now I know it was this young lady's job to mention all of these discounts to us, clean the games, bag them up and take our money before we left. She could have done all of these things and left it at that. But it was nice to see how she handled her customers in a way that was courteous and professional. It was apparent she wanted to make us feel like happy customers who would soon return to their store after we left the building. And you know what? With customer service like that, I think we'll be going back there in the future.
Between saving money, good customer service, and getting three games and a movie for like $8 (where else can you get that kind of a deal for all this entertainment?), we left the store knowing this is how a good video rental store should be operated.
The clerk who helped us that day didn't have to necessarily go that extra mile to make sure we were pleased with our service, but she did, and if all of the staff in the store treat their customers like she treated us, especially during busy hours, they should have a good business on their hands.
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i would invite you to visit the Ft. Scott Movie Gallery store. We have great rental and purchase specials (on both movies and games), a friendly shopping environment, and we take great care to keep our customers happy. Stop in and say hi!
-- Posted by moviewatcher on Wed, Jun 13, 2007, at 4:55 AM
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Breakout players are what every fantasy owner hopes to find in each sport. They usually lead to championships because you are getting more value out of the players you select. Think about football season. People who drafted Adrian Peterson got exactly what they wanted and expected from him, but that didn't guarantee them a championship. Now think about the owners that got Arian Foster and Darren McFadden in the middle rounds, those are the players that led teams to the top of their leagues. These are the MLB players that should be able available as fantasy baseball sleepers in 2011 fantasy baseball.
Rajai Davis – OF – Toronto Blue Jays
Davis might be the best option for fantasy baseball owners looking for cheap steals late in drafts. While Davis has been around for a while, this may be his real breakout season. (more…)


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Find and Create Events on Twitter!
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PC Games
This page contains Cheats for Kohan: Immortal Sovereigns organized by sections for PC. This game has "Strategy" as genre, made by Timegate Studios, released on Mar 14, 2001. If you can't find a hint or secret in our list, then please check this page periodically for the latest updates.
Boxshot & Details
- Developer: Timegate Studios
- Publisher: Strategy First
- Genre: Strategy
- Release: Mar 14, 2001
- ESRB: Teen
From: PlasterBoy76
Submit Cheats
If you know cheat codes, secrets, hints, glitches or other level guides for this game that can help others leveling up, then please Submit your Cheats and share your insights and experience with other gamers.
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Stuck in this game? Set a specific, clearly defined question and let other gamers answer your question or view answers to previously asked questions. If you think you are an expert then please try to help others with their questions.
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text: The Academy has announced this years medalists for the Student Academy Award. The medalists in the animation category are An Object at Rest, Soar, and Taking the Plunge. The specific placement for the films- gold, silver, and bronze- will be announced on September 17 at an awards ceremony in Beverly Hills, California. Animated shorts also showed up in the alternative category, with Chiaroscuro and Zoe both also placing there.Read More


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Bryan "Jop Jop" Joplin Dies in Wreck
Friday, September 11, 2009
MMA fighter killed in desert accident
La Habra man was killed in 3-vehicle collision, CHP says.
By PETER SCHELDEN
The Orange County Register
Comments 8 | Recommend 0
Bryan "Jop Jop" Joplin, a 33-year-old mixed martial arts fighter from La Habra, was found dead Thursday night about 11:15 after a highway accident midway between Palm Springs and the Colorado River, said Sgt. Steven Ahrens of the California Highway Patrol.
Joplin was killed driving a pickup heading east toward the river when he was in a crash with another eastbound Dodge pickup towing a boat and a westbound Jeep Cherokee, Ahrens said. He said emergency workers found Joplin dead at the scene of the accident.
The vehicles were traveling state Route 62, about 32 miles west of Vidal Junction.
The driver of the Jeep Cherokee, Will Kammerdiene, 28, of Parker, Ariz., was taken to an Arizona hospital with moderate injuries. The passenger and driver of the pickup were unhurt, Ahrens said.
The CHP continues to investigate the accident. Ahrens said the area is a no-passing zone for eastbound traffic, but said it is still unclear whether any passing was attempted.
Joplin was a Dana Hills High School graduate of the class of 1994, according to his MySpace page.
"The fun and good times consist of the river, the desert, the beach, and pushing the limits looking for the biggest thrill/rush I can get!" his MySpace page reads. "I live life to the fullest with no regrets!"
The MMA Web site sherdog.com records Joplin winning five professional fights between 2004 and 2007, and losing his sixth and final recorded match in November 2007.
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by Anton Shilov
At its financial analysts day on Tuesday Advanced Micro Devices released additional details about its future products for client personal computers. Apparently, in 2012 there will be no mainstream or entry-level central processing units (CPUs) without integrated graphics as AMD will address all the markets, except the high-end desktop, with its Fusion accelerated processing units (APUs).
The most powerful microprocessor for desktops that AMD will offer in 2012 will be code-named Komodo and which will have eight cores powered by improved Bulldozer micro-architecture. It is noteworthy that the server brother of Komodo - the code-named Sepang chip - will have up to ten cores, whereas traditionally AMD's most powerful desktop chips offered similar features as server chips. Perhaps, in 2012 the chip designer will change its tactics and client and server chip designs will be completely different.
For performance-mainstream, mainstream and entry-level desktops and laptops AMD plans to introduce Trinity family of APUs, which will have two or four next-generation Bulldozer x86 cores as well as DirectX 11-capable integrated graphics engine. AMD's Trinity family made using 32nm SOI fabrication process will likely be the company's biggest line in terms of volume.
For low-power desktops, ultra-thin notebooks, netbooks and other low-power devices the Sunnyvale, California-based AMD intends to offer Krishna and Wichita APUs powered by one to four enhanced Bobcat cores as well as DirectX 11-compliant graphics core. Advanced Micro Devices plans to utlize a bulk 28nm manufacturing process to build its next-generation low-power APUs. Unfortunately, at present it is unknown whether the company plans to use TSMC's or Globalfoundries' 28nm fabrcation process.