text:
Alkaline Phosphatase Knock-Out Mice Recapitulate the Metabolic and Skeletal Defects of Infantile Hypophosphatasia†
- †
Presented in part at the 18th Annual Meeting of the American Society for Bone and Mineral Research, Seattle, WA, U.S.A. (September 7–11, 1996) and the 46th Annual Meeting of the American Society of Human Genetics, San Francisco, CA, U.S.A. (October 30–November 2, 1996).
Hypophosphatasia is an inborn error of metabolism characterized by deficient activity of the tissue-nonspecific isoenzyme of alkaline phosphatase (TNSALP) and skeletal disease due to impaired mineralization of cartilage and bone matrix. We investigated two independently generated TNSALP gene knock-out mouse strains as potential models for hypophosphatasia. Homozygous mice (–/–) had < 1% of wild-type plasma TNSALP activity; heterozygotes had the predicted mean of ∼50%. Phosphoethanolamine, inorganic pyrophosphate, and pyridoxal 5′-phosphate are putative natural substrates for TNSALP and all were increased endogenously in the knock-out mice. Skeletal disease first appeared radiographically at ∼10 days of age and featured worsening rachitic changes, osteopenia, and fracture. Histologic studies revealed developmental arrest of chondrocyte differentiation in epiphyses and in growth plates with diminished or absent hypertrophic zones. Progressive osteoidosis from defective skeletal matrix mineralization was noted but not associated with features of secondary hyperparathyroidism. Plasma and urine calcium and phosphate levels were unremarkable. Our findings demonstrate that TNSALP knock-out mice are a good model for the infantile form of hypophosphatasia and provide compelling evidence for an important role for TNSALP in postnatal development and mineralization of the murine skeleton.


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Sandra & the late Leonard Zimmerman
Directions: From Edina MO
go north on Hwy 15 approx. 2miles to Hwy EE and continue north to Hwy K then east approx. 4miles to Rule Ave
then south to site. From Memphis MO take Hwy 15 south for 17miles to
Hwy K then east approx. 6miles to Rule Ave then south to site.Watch for
Shop tools
of welding rodstorchdrill pressgenerator(7000 watt)pressure washerorganizer with boltsready heaterparts washerair tanksair regulatorhoseoil transfer pumpair tank bead seaterlarge bench viceCraftsman vicetable sawwood clampsbench grinderseveral grease gunsair over hyd.bottle jackseveral hyd.bottle jacksjack standsextension ladder(32ft fiberglass)wooden step ladder2
aluminum ladderscreeperbarrel cartbarrel pumpsflood lightsDeWalt
sawseveral DeWalt drillssawnew electric motorselectric wood splitterfencing suppliespost hole digger2-1in air impactsseveral 1/2in impactsair chuckslots of air tools3 tool chests3/4in
socket setSnap On 3/4in drive torque wrenchlots of 1/2in,3/8in ,1/4in drive Craftsman socketsextensionsswivelsbreaker barssome full
setshammersscrewdriverslarge pry barstape measuresbead breaker for semi tireChannel Lock and Ridgid pipe wrenchesfilter wrenchesdrill bitsmetric gear wrench set 8-19 mmstandard gear wrench set 3/8-3/4torque wrenchlots of metric and standard
wrenches and setslots of standard and metric impact sockets(shallow and
deep well)3/8in and 1/2in drive2 sets of 3/4in drive impact socketslots
1in drive impact sockets up to 3 3/8in1in extensions and swivelswiring
supplieshole saw kit Halogen leak detectorhoesforksshovelsrakes
Oil and Cleaners
2 partial 55gal barrels of Schaeffer 15w-40 engine oil1- 55gal barrel Schaeffer 10w-30 engine oil1-55gal barrel of Zep truck wash solution T.N.T.oil drainer3-275gal totes2-1000gal tanks with some drain oil
Truck Parts(semi)
several new and used 22.5-24.5 Aluminum wheelstruck fuel tankfenderslots of misc truck parts
Oakwood table 68in with 4 10in self storing leaves8 acorn pressback chairssofahigh chairlarge corner computer deskprinter3 piece King size
bedroom setbook cases
Vehicles Lawn mower 4-wheeler
2006 Ford Mustang GT 5 speed 92,091 miles
2003 Chevy Tahoe 268,130 miles
2003 Chevy S-10 155,464 miles ZR2 4x4
2001 Chevy 2500 HD extended cab 4x4 180,000 miles
8.1 motor with Allison transmission
2009 Kawasaki 650R Ninja 6077miles(as is)
Lawn mower(Simplicity Landlord 50in 3387hourslawn
sweepKawasaki Bayou 220 4-wheelerATV sprayer
Tractor and Machinery
885 David BrownGehl 4625sx skid steer 1065 hours with bucket and forksMidwest BB20 box blade 72inNew Holland 7ft 455 pull type sickle bar mowerRhino 4ft 3 point brush cutterFerguson 3point 2 bottom plow8ft disc2-16ft bumper hitch
large fishing rodsgolf clubsice chestBBQ grillrunner sledBrass Quoite setwhite tailgas lanternantlers large vertical air compressorb battery chargerLincoln AC 225
welderlots angle grinderslarge Vulcan Anvilcutoff sawfl oor jackLincoln
Lunch served on grounds. Proceeds go to Mennonite schools.
Clinton 660.341.8036
Mark your calenders for this November 5th auction. Due to the sudden death of Leonard in August we will be selling his shop items, truck parts, vehicles, and machinery. Hope to see you November 5th!!
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subset: commoncrawl


text:
Please refer to JobSuchmaschine in your application
Senior Javascript Developer Job – Front Office – Structured Products – Zürich
Javascript developer, Lead Front End Developer, Senior web developer, Senior Javascript developer
Are you an experienced javascript developer interested in developing cutting edge front ends for a globally used trading platform? Are you interested in joining a small and diverse development team that are truly passionate about javascript / web development? Would you like to gain exposure to working with Front Office business users here in Zürich? If so this could be the perfect javascript developer job for you!
If you are heavily reliant on frameworks such as AngularJS or React.JS in your day to day role, you are probably not right for this team. The team uses frameworks where there is a need but are really looking for someone that has strong core Javascript development skills to take them forward and revamp the existing frameworks and APIs they have created.
If you are interested in finding out more about this Senior Javascript developer, please send your CV to
email@example.com alternatively if your CV is not up to date, you can call me on +41 44 5785 330


text:
Truglo Tru Bead Universal Fosforlu Arpacıklar :
Lif Çapı .060"
Orijinal arpacığın yerine takılır,
4 değişik renkte
CNC makinalarda üretilen fosforlu arpacık.
Güneşli V.D. - 69940038368
Ticaret Sicil No: 493039 - 440621
The following information has been self-reported by the entity to which it relates for the purpose of assignment of a unique identifier (CUI). The information has not been verified nor has the entity been authenticated, credentialed, verified, or investigated in any way.


text:
Cover up and cover ground. The Uptown & Downtown Shades feature a silver aviator design, brown ombré square lenses, caramel leather rims, and tortoiseshell arms. Perfect for nailing that oversized look.
*Leather/Synthetic Materials
*5.75"/14.5cm width
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California Residents: Proposition 65
If you're not utterly obsessed with your recent purchase, it's now so easy to send it back! All US returns can be completed online using our fast, hassle-free system. Check out the links below for more details.
Opened makeup, earrings, ear cuffs and panties cannot be returned.


text:
Meet the BVCA's new chief executive
Mark Florman, born in the UK to Swedish parents, joins the BVCA as chief executive after more than 30 years in business which included a seven year stint at UK private equity firm Doughty Hanson from 2001 to 2008. His tenure begins on March 14.
Florman's main challenges will be combating the threat of punitive regulation in the wake of the economic crisis, and rejuvenating the industry's image by educating politicians and the public as to the benefits private equity and venture capital can bring to the economy. He will also have to prove to its members that the BVCA is more than just a lobbying tool.
Florman said: "The next few years will be crucial for the fortunes of the UK economy. I believe that a sustained recovery requires the UK to develop its venture capital sector further and to support its entrepreneurs. The BVCA and its members are central to these efforts. I look forward to providing the private equity and venture capital sector with energetic leadership in pursuit of its objectives".
He began his career at The Northern Trust Bank of Chicago in 1981 before joining County Bank in 1986 and then Enskilda Securities where he ran the Swedish origination group. In 1992, he founded boutique investment bank Maizels Westerberg with four other partners, including Sten Westerberg, then under-secretary at Sweden's finance ministry. He became managing partner of the bank after the death of Spencer Maizels in 1994.
In 2000 he sold Maizels to create ArosMaizels, now one of the largest banks in the Nordic region, and become the new company's chief operating officer.
He then moved to buyout firm Doughty Hanson in 2001, where he worked as a senior principal. He also served as chairman of LM Glasfiber, a Doughty Hanson portfolio company which makes wind turbine components.
Florman is an avid sports fan, and keen skier. During his time as managing partner at Maziels, he would fly the bank's staff to an Alpine ski resort for an annual get-together on the piste.
He has been active outside work, serving as senior deputy treasurer of the UK's Conservative Party. Last year, he became chairman of the Centre for Social Justice, a UK think-tank he helped to found in 2004 which examines methods of combating poverty. He is a non-executive chairman of 8 Miles, a private equity group targeting investments in Africa fronted by concert-organiser Bob Geldof.
In 2004, Florman founded Build a School in Africa, which has completed the development of over 100 primary schools in East Africa. He is on the board of the Swedish Chamber of Commerce and is an ambassador for the Royal Albert Hall.
Hugh Lenon, chairman of the BVCA and managing partner of buyout firm Phoenix Equity Partners, said: "In his three years at the helm of the BVCA, Simon Walker has transformed the standing of the private equity sector and has been a ceaseless champion of venture capital. We are delighted to have found such a distinguished figure, with an extraordinary array of experiences, to succeed him. I know that Mark Florman will be a really strong standard-bearer for our exciting and important industry."
Walker, a New Zealand national, was brought in to head the BVCA from media group Reuters, where he worked in corporate communications and marketing. He had also worked in senior public relations roles for British Airways and Queen Elizabeth. He joined at a time when the trade body was catapulted into the spotlight following a UK parliamentary enquiry into private equity, which investigated the industry's use of debt, its favourable tax treatment, and its lack of transparency. Industry figures praised Walker's success in turning private equity into a "non-news story" during his time in charge. He has no immediate plans once he steps down from his role at the BVCA on March 14th, other than spending time with his wife.


text:
Sir 80 ka root kitana hoga3
- animaldk
- Ambitious
- Shravani83
- Genius
This Is a Certified Answer
Certified answers contain reliable, trustworthy information vouched for by a hand-picked team of experts. Brainly has millions of high quality answers, all of them carefully moderated by our most trusted community members, but certified answers are the finest of the finest.
√80 = 8.944 (rounding off to three decimal places).
- renesmee
- Expert
√80=4√5=8.9442 is the answer carrect now


text:
0 ReviewsWrite a Review
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Judith Jack
'Matrix' Convertible Pendant Necklace
Product not available
HideDetails & Care
Two-tone pavé crystals highlight a teardrop pendant's geometric cutouts. The necklace's station chain can be worn long or doubled for an alternate look.
- Toggle closure.
- Approx. length: 36" adjustable to 18".
- Approx. pendant dimensions: 1 1/8"W x 1 7/8"L.
- Sterling silver/14k-gold plating/marcasite/crystal.
- By Judith Jack; imported.
'Matrix' Convertible Pendant Necklace
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text:
Face Off!
Good morning and welcome back to the sneak attack. Yesterday's rise chewed through the few flies that littered the tape and quelled prior tries. "The trannies were just too strong from the start," said Hoofy the bull feeling all kinds of smart, "the only wisdom that's left to depart I will do with young Boo with a quick heart to heart:"
Hoofy: Cookie-please don't get stubborn again and draw a line in the sand. I know you see the same things I do. A bevy of charts (including the all-important BKX) has more reverse dandruff than a Head & Shoulders convention! It doesn't matter if you believe the hype...you've gotta climb into the mindset of the masses. People are confused and quarter-end is approaching. Have you ever heard of inertia?
Boo: I agree that it's perfect. Think about it--the hedge funds are lining up to buy the telegraphed acne, sentiment is lopsided, volatility (fear) levels are at their lowest level since '96 (VXN at all-time low), insiders are dumping, rates are rising, geopolicial risk remains (which should, by definition, price a 'risk premium' into stocks) and many feel we're looking at a double dead end politically. I know--let's buy stocks!
Hoofy: You just don't get it, do you? The stock market is the world's largest thermometer and the powers that be will make quite sure that we're flush with liquidity. Besides, history dictates the most structural shifts will ripple through the credit markets first and if you've read Professor Reynolds, you'd know that they're relatively sanguine. I would urge you to read his morning missive today as he weighs both sides of the trade rather cogently.
Boo: The risk is in one of two scenarios: Either everyone is loaded up for the quarter-end sprint and the ref blows the whistle (offsides!) or we get the breakout and upside capitulation. If the second script unfolds and we make marginal new highs, there will be NOBODY left to cover. That would set the stage for a particularly painful 'pop and drop.'
Hoofy: One step at a time, right? If this is indeed liquidity driven, global equities would rally (see Brazil and Asia), the metals would lift (gold poked through the 200-day), the small caps would sparkle (the Russell took out the June highs yesterday) and an ever-present bid would exist (you tell me).
Boo: I've got eyes, bro, and I can see the same things you do. But everyone is looking at the VXO chart (breaking down) and piling onto the sell side of volatility. It's so inexpensive that protection can be purchased very, very cheaply. It's a small price to pay for defined risk, in my view, but that's just me.
The two critters eyed each other and both knew that they were in for a dogfight. The next ten days would usher in the Iraqi semanticfest, quarter-end, Elmer, earnings and a long weekend (posturing included). We've been drifting sideways for over a month and energy is sufficiently stored for an outsized move. I would simply remind ye faithful that discipline is the common denominator of any successful trading strategy.
Good luck today.
- 1
Todd Harrison is the founder and Chief Executive Officer of Minyanville. Prior to his current role, Mr. Harrison was President and head trader at a $400 million dollar New York-based hedge fund. Todd welcomes your comments and/or feedback at email@example.com.
The information on this website solely reflects the analysis of or opinion about the performance of securities and financial markets by the writers whose articles appear on the site. The views expressed by the writers are not necessarily the views of Minyanville Media, Inc. or members of its management. Nothing contained on the website is intended to constitute a recommendation or advice addressed to an individual investor or category of investors to purchase, sell or hold any security, or to take any action with respect to the prospective movement of the securities markets or to solicit the purchase or sale of any security. Any investment decisions must be made by the reader either individually or in consultation with his or her investment professional. Minyanville writers and staff may trade or hold positions in securities that are discussed in articles appearing on the website. Writers of articles are required to disclose whether they have a position in any stock or fund discussed in an article, but are not permitted to disclose the size or direction of the position. Nothing on this website is intended to solicit business of any kind for a writer's business or fund. Minyanville management and staff as well as contributing writers will not respond to emails or other communications requesting investment advice.
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"I was overworked and not taken seriously when I shared my pain and concern that something was wrong."
Violent Femmes to tour Wollongong
Desiree Savage Listen to 'Blister in the Sun' live with the
Russell Crowe cleared in rapper Azealia Banks case
Amy Croffey Russell Crowe will not be charged with forcibly removing rapper Azealia Banks from his Beverly Hills Hotel party.
Isla Fisher and Sacha Baron Cohen confused by AACTAs red carpet sausage demonstration
Amy Croffey Mel Gibson, Isla Fisher, Sacha Baron Cohen, Boy George, Paul Hogan and Geoffrey Rush all helped make up the star-studded line-up at the AACTA Awards on Wednesday night, but it was demonstrators dressed as sausages who really stole the show.
Lena Dunham had the perfect response to being asked if she is pregnant
Nicole Economos Women of all sizes know how jarring it can be when someone asks if they're expecting and they're not. But next time it happens, we are going to take a page out of Lena Dunham's book.
Tom Ford sticks by comments that all men should experience anal sex to 'understand women'
Mary Ward The designer and director defended comments he made in 2004, after propositioning a male journalist.
David Beckham bares his body for UNICEF's powerful child violence campaign
Nicole Economos Along with his football career and family, David Beckham is renowned for his tattoos and chiselled physique, but the father-of-four's recent project uses his body art to illustrate the brutal reality that physical and psychological abuse can mark children forever.
Natalie Bassingthwaite revisits Wollongong High: video
Desiree Savage 'I got told once ... that if I didn't make it by the time i was 16 I was never going to make it.'
Kim Kardashian shares rare photos of Saint West to celebrate his first birthday
Nicole Economos Although Kim Kardashian has kept a relatively low profile since the Paris robbery and hospitalisation of Kanye West, the star celebrated her son Saint West's birthday in a subtle way.
New album awaits The Pinheads
Desiree Savage Wollongong band drops new single 'Wildfire' ahead of debut album release next year.


text:
Steak Sauce London Broil
Total Time
Prep 5 mins
Cook 8 mins
This one has only three ingredients, and couldn't be easier! Prep time does not include marinating time.
Ingredients Nutrition
- 3⁄4 cup A.1. Original Sauce
- 1 1⁄2 lbs top round london broil beef or 1 1⁄2 lbs flank steaks
- 1⁄4 cup spicy brown mustard
- Combine 1/2 cup of the steak sauce and the London Broil in a large resealable plastic bag; seal and marinate in refrigerator for at least 1 hour and up to 8 hours.
- Stir together the remaining steak sauce and the mustard in a small bowl; set aside.
- Preheat grill to high; remove steak from bag, discarding marinade.
- coat rack of grill with cooking spray and cook steak, turning once, to desired degree of doneness, 8 minutes for medium-rare.
- Serve thinly sliced steak with the mustard steak sauce.
Most Helpful
SERIOUSLY GOOD STEAK WITH STEAK SAUCE AND MUSTARD SAUCE!!! Fool proof simple, too!


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Related quotes
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"History is not going to be kind to liberals. With their mindless programs, they've managed to do to Black Americans what slavery, Reconstruction, and rank racism found impossible: destroy their family and work ethic."
"If Goddess religion is not to become mindless idiocy, we must win clear of tendency of magic to become supertition. Magic - and among its branches I include psychology as its purpose to describe and change consciousness - is an art."
"I see myself as a citizen of the planet. Even as a child, I always found it mindless to root for your own team. I was puzzled by the fact that people said their own team was better than other teams simply because it was theirs."
"There is no individual on this Earth more determined than I am to end this country's wretched and mindless bloodshed and destruction."


text:
iHerb Customer Reviews
Savings of: $0.79 (20% off)
Please note limited shipping months for this item:
This item is heat sensitive. It is only available for purchase between October 1st and June 14th. We temporarily discontinue the item during the summer months, from June 15th - September 30th, because it might melt or spoil during transit.
I`ve had better
Posted by MindsurfNorway on Aug 22, 2011
It might be just this batch, but this was kind of dry, and sort of flavourless.
Hard as Rock
Posted by 5235827532288943003 on Jun 06, 2016
Can't even sink my teeth in. I wonder if it's was over heated during the delivery. I ended up throwing the whole choc away.
This came only one I bought two products.
Posted by 4711066472180517727 on Nov 05, 2016
This came only one I bought two products. What should I do?
Items 1-3 of 3 total


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Antique Venetian Glass Beads, Red with Copper Aventurine Inclusion Rectangle Glass Bead Dangle Earring
14K Gold Bracelet "I LOVE YOU" in Rustic Wood Fence Letters 16g
Sterling Silver Garnet Cross Massive Cross Pendant 11.65 carats
Large Enamel Santa Pendant Brooch 2.5" Free Shipping
Antique Victorian Silvertone Pocket Watch Chain
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Signed ART AB Red Rhinestone Necklace and Matching Clip Earrings
Antique Victorian Ribbon Slide Charm
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14K Yellow Gold LAZULI LAPIS Ring - HEAVY Massive Estate Jewelry
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Antique carved Cameo winged eros dancing cupid with flutes greek God of Love Portrait necklace clasp Vintage Choker & Brooch
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3 Bedrooms Detached House for sale
Deer Close, Norton Canes, Cannock, Staffordshire
*** extended *** cul-de-sac *** dixons estate agents offer for sale this well presented extended three bedroom detached property located in a cul-de-sac. (contd...)
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KCG tech chief to leave
The chief technology officer at KCG Holdings is to leave the electronic trading firm to pursue interests outside the financial markets, bringing to an end a 14-year career in the sector.
Jon Ross, who is responsible for all of KCG's technology, information operations and infrastructure, will step down and be succeeded by Mike Blum, KCG's global head of client technology, on October 1, the company said in its second-quarter results on July 21.
Ross is leaving to "pursue a variety of personal projects in the technology space, unrelated to trading and markets," KCG said.
Ross had been the CTO at Getco prior to the high-speed trading firm's merger with Knight Capital to form KCG in July 2013. Before that, he was CTO at Nasdaq and other companies including Island ECN, one of the first US electronic trading platforms to rival established exchanges.
Before his career in trading technology, Ross worked for the US video game developer behind titles including SimCity2000 and SimTower, and also on programming missile-guidance systems at a Californian defence firm.
He told Financial News in 2012: "The early part of my career was great fun but, after joining Island, I became hooked on trading systems."
Blum joined KCG in the client technology role in January. A former head of execution services at Getco, he was most recently the CTO at high-speed trading firm Teza Technologies. As well as Blum, KCG also recently hired Redi Holdings' CTO Josh Schubkegel and Brian Freyburger, who was CTO at another high-speed firm Tower Research Capital.
KCG's results for the second quarter showed that revenues rose 22% to $319.9 million compared with the second quarter of 2015, while pre-tax profits were $54.6 million, compared with a loss of $57.1 million a year earlier.
However, those figures included a pre-tax gain of $33.4 million from the sale of a portion of its investment in exchange operator Bats Global Markets. KCG retains a 13.7% stake in Bats following the sale. Excluding the gains from the Bats stake, KCG's revenues grew by 9.4% year-on-year.
Daniel Coleman, chief executive of KCG, said in a statement: "Despite relatively poor market conditions for most of the second quarter, KCG produced reasonable financial results. KCG market-making in US equities had another strong quarter. In addition, our franchise ETF desk and KCG BondPoint both showed continued growth in revenues and market share."
KCG, whose operations span market-making, agency broking for institutions, and operating trading venues, said its institutional trading activity was impacted by the EU referendum in the UK, which affected US and European equity market volumes.
Revenues in the global execution services segment, which comprises agency execution services and trading venues, rose 7% from the second quarter of 2015 to $68.1 million, although this was 11% below revenues in the first three months of 2016.


text:
In Kansas, there are several unique license plate designs available to choose from. This list is available online here, Kansas Distinctive License Plates.
State law requires that there can be only one letter combination per personalized plate in the state of Kansas. Please go to the Personalized Plate Look-up to check availability.
Personalized plates can only be picked up at the Mission location. You will receive a notification from the state when your personalized plate is shipped to our office. You will need to bring your current license plate issued to you, the current registration and insurance information.
Fill out the Manual Personalize Plate Application. The cost for personalized plates is $45.50 for an Auto/Light Truck or Motorcycles. Anyone can order a personalized plate for a vehicle at either Motor Vehicle location. You may have up to 7 letters or spaces for an Auto/Light Truck personalized plate and up to 5 letters or spaces for a Motorcycle personalized plate. There is no punctuation allowed on personalized plate lettering.
If your license plate is lost or stolen from your vehicle, you must file a police report in the city in which the loss occurred. Bring the police report, current registration, and current insurance information to either motor vehicle office to obtain a replacement plate. This must be done by the registered vehicle owner, or the registered owner may give someone Power of Attorney to process this transaction on their behalf.
A 60 day tag may be purchased by bringing the assigned title, bill of sale, and current insurance information to either Motor Vehicle location. The 60 day tag will be valid for the first 60 days from the date of purchase. The cost of the 60 day tag is $8.00 and is payable by cash only.
Enter a name, address, property I.D., or Kansas Uniform Parcel Number (KUPN) to get quick access to maps and information about an address or location.
111 S Cherry St, Olathe, KS 66061 | 913-715-5000 | TDD: 800-766-3777© Johnson County 2016


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November 14, 2007
CONSTANCE M. GRIFFITH, JENNIFER S. BROWN, AND TERESA M. CUMMINGS, PLAINTIFFS,v.JOHN T. PEPMEYER, PERSONALLY, JOHN T. PEPMEYER, NOT PERSONALLY, BUT IN HIS OFFICIAL CAPACITY AS STATE'S ATTORNEY OF KNOX COUNTY, ILLINOIS; KNOX COUNTY, ILLINOIS, A MUNICIPAL CORPORATION, AND STATE OF ILLINOIS, DEFENDANTS.
On October 2, 2007, a Report & Recommendation was filed by Magistrate Judge Byron G. Cudmore in the above captioned case. More than ten (10) days have elapsed since the filing of the Report & Recommendation, and no objections have been made. See 28 U.S.C. § 636(b)(1); Fed. R. Civ. P. 72(b); Lockert v. Faulkner, 843 F.2d 1015 (7th Cir. 1988); and Video Views, Inc. v. Studio 21, Ltd., 797 F.2d 538, 539 (7th Cir. 1986). As the parties failed to present timely objections, any such objections have been waived. Id.
The relevant procedural history is sufficiently set forth in the comprehensive Report & Recommendation of the Magistrate Judge. Suffice it to say that Plaintiffs have brought this litigation alleging that they were discriminated against on the basis of their gender in violation of Title VII and 42 U.S.C. § 1983.*fn1 The Court concurs with the recommendation that Defendant Pepmeyer in his official capacity is a proper defendant for Plaintiffs' Title VII claims, and that at this stage of the proceedings, Plaintiffs must also be allowed to pursue the question of joint employment by Knox County. It is also apparent that the claim against the State of Illinois is duplicative of the claim against Defendant Pepmeyer in his official capacity, as it is well-established that in Illinois, a suit against a county state's attorney is a suit against the state. Hernandez v. Joliet Police Dept., 197 F.3d 256, 265 (7th Cir. 1999). With respect to Plaintiffs' §1983 claim, the Magistrate Judge has recommended that Defendant Pepmeyer should be dismissed in his official capacity, as the injunctive relief sought is moot and any claim for monetary relief is barred by sovereign immunity. The Court agrees.
Accordingly, the Court now adopts the Report & Recommendation [#24] of the Magistrate Judge in its entirety. Defendants' Motions to Dismiss [#13, #16. And #19] are GRANTED IN PART and DENIED IN PART. Plaintiffs are given leave to file their proposed Amended Complaint [#21 Exhibit A], and the rulings contained in this Order shall apply to the Amended Complaint. The State of Illinois is dismissed as a party defendant. The Title VII claims shall proceed against Defendant Pepmeyer in his official capacity and Knox County. The § 1983 claims shall proceed against Defendant Pepmeyer in his individual capacity. Plaintiffs' request for equitable relief is denied. This matter is referred to the Magistrate Judge for further proceedings.
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UPDATE 1-India's Adani Enterprises Australia CEO says coal project "back on track"
* Adani says will help, not hurt environment (Adds more Adani comment, details)
MOSCOW, Sept 30 Russia saw net capital outflow of $7.11 billion in the first half of this year, according to data published on the central bank's website on Friday.
The data showed current account surplus in the fist six months of the year was $13.7 billion. (Reporting by Alexander Winning; Writing by Lidia Kelly; Editing by Dmitry Solovyov)
* Adani says will help, not hurt environment (Adds more Adani comment, details)
To access the newsletter, click on the link: http://share.thomsonreuters.com/assets/newsletters/Indiamorning/MNC_IN_12062016.pdf If you would like to receive this newsletter via email, please register at: https://forms.thomsonreuters.com/india-morning/ FACTORS TO WATCH 11:00 am: Winter session of parliament continues in New Delhi. 11:45 am: Revenue Secretary Hasmukh Adhia to attend meeting of Heads of Revenue of BRICS countries in Mumbai. 3:00 pm: Trade Min
HANOI, Dec 6 Shares of Sabeco, Vietnam's biggest brewer, jumped the maximum allowed 20 percent in thin volume on debut on Tuesday to hit 132,000 dong ($5.8), data from the Ho Chi Minh Stock Exchange showed.


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Top-notch full service lab, 6 years in the business. Original owner. Very solid growth with solid client base. Specializing on full mouth, complex, and aesthetic cases. High quality denture department. Best ceramists.
Financials (USD)
Asking Price Between $500,000 and $1,000,000
Sales Between $500,000 and $1,000,000
Profit Available On Request
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purchase help!
madecov wrote:
B&H Photo
Berger Brothers
These are a few REPUTABLE re sellers.
This is a great list and you won't go wrong with any of them. I would suggest something further if this is your first DSLR. Find a good reputable Camera Store(Not Best Buy or Sears!) and pay what they sell it for. You will get need service and advice that surpasses any savings that you will get from mail order. (B&H and Adorama are good over the phone...if you want to deal with being a bit rushed). These dealers are some times hard to find. For example, there are only two that I would put in that category in the Seattle area(Kenmore and Glazers). That support is worth it and often times the pricing is competitive.
Good luck!
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Beamish Wild
Avg. Saving £4.40*
* average saving based on two adults and two children
More About This Offer
Welcome to the home of adventure in the North East! Set in the Treetops of our ancient woodland, our High Ropes Course is 2 hours of non-stop fun and challenges guaranteed to get your adrenaline pumping. We've packed your fun day out in the treetops with 4 zip-wires, rope bridges, swinging tires and you will be finishing off with the awesome Powerfan free-fall experience!
If you do feel a bit peckish before or after your adventure or maybe fancy a glass of wine/beer (definitely after!), The Stables Bar and Restaurant is just 50 yards away.
Beamish Wild has been awarded Tripadvisor's Certificate of Excellence in 2014 and 2015.
Contact Information
- Beamish Hall, Stanley, County Durham, DH9 0YB
- Opening Times: Please see website for opening times
- 01207 233 733


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Sports Bar & Grill Marylebone
Located in Marylebone Station, Sports Bar and Grill shows all the sporting action on 52in HD screens. The venue serves fabulous food from an open kitchen, and you can reserve a table to watch sport while you dine. Why not pop in on your way to a match at Wembley Stadium or Lord's? You'll also find Sports Bar and Grill branches in Victoria and Farringdon.
|Typical meal price:
|From £26.00 (USD32.73) per diner
£26 to £40
Venue Details & Map
Sports Bar & Grill Marylebone
- Address
Melcombe PlaceRegent's ParkLondonNW1 6JR
Yelp Reviews
Lots of tv's, short on quality. This sports bar is purely for the purpose of watching games, don't expect the food to be anything above barely edible. The wings are cold, and although we ordered 20, they delivered 17 wings.
In addition ensure you bring your patience as the staff are not attentive and hard to flag down. Will I come back to this bar, yes, but not by choice.more
Not sure where to start ! Food is below average. It came out cold the first time, we sent it back and it came out cold the second time. The service is below average. The waitresses upstairs were miserable and were clearly not happy to be working. . The venue is supposed to be a sports bar, but they have completely missed the mark, especially with the food. Would never recommend this place to a...more
Food was absolutely horrible. Really bad. Sausages disgusting. What's worse is no one asked how our food was even though we barely ate half of it! They should have been switched on and asked, then offered a refund.
Never going back.more
I'm sorry I didn't realize a Resturant / sports pub can actually destroy an experience with a simple burger !
The place is a sports pub and has a nice selection of beer , they are nice and cold .
And surprisingly they also have good selection of Italian wines
I walked in & noticed not manny people were eating (that should of been a clue) .
I ordered calamari, you get less...more
Use this place all the time as convenience. Food has gotten worse over time but still not awful. Staff are always friendly and the managers go out of their way to make sure you enjoy the experience.
The only disappointment is the food quality, chefs seem to change all the time and the meat seems to be a cheaper version of the one you'll have had a few weeks ago.more


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Lucky NumbersHD Closed Captioning
Nora Ephron
Open iTunes to preview, buy, and download this movie.
About the Movie
While lots of people dream of winning the lottery, one man hatches a more ambitious plan than just buying a ticket and hoping for the best in this satiric comedy. Russ Richards (John Travolta), a weatherman on a local TV station in Harrisburg, Pennsylvania, sells snowmobiles on the side, but both careers are in a rut thanks to an unusually warm winter. Russ's girlfriend Crystal (Lisa Kudrow) appears on the State Lottery's weekly televised drawing, pulling the numbered balls out of the rotating bin. With the help of a few of his less scrupulous friends - among them sleazy strip joint proprietor Gig (Tim Roth), small time hood Dale The Thug (Michael Rappaport), and Crystal's sleazy cousin Walter (Michael Moore) - Russ figures out a way to rig the drawing and have Crystal pull numbers that they happen to own. However, Russ discovers that making the scheme work and keeping everyone quiet about it is more trouble than it's worth. The supporting cast includes Chris Kattan, Ed O'Neill, and Bill Pullman; Nora Ephron, who previously worked with Travolta on the comedy hit Michael, directed.
Rotten Tomatoes Movie Reviews
- Reviews Counted: 96
- Fresh: 21
- Rotten: 75
- Average Rating: 4.0/10
Top Critics' Reviews
Rotten: [Ephron] seems to condescend to the characters.
Rotten: The laughs are few in this inert, ungenerous comedy.
Rotten: A visually unattractive picture of meager verve and dynamism.
Rotten: Gags hit with sledgehammer heaviness and most of them mock the movie's own characters so relentlessly -- and mirthlessly -- that one winces rather than laughs.
Customer Reviews
Mildly entertaining
I never heard of this movie until I saw it on iTunes and after watching it I now know why. The story line is somewhat predictable in the way events unfold and the characters are average at best. In a nutshell the story is about about a weatherman (Travolta) working at the local TV station who made some bad investments and is about to lose his life of luxury due to a run of bad luck. Travolta and his shady friend hatch a plan to rig the state lottery and retire rich. The plan involves the station's lottery "ball girl" who is eager to join in. They manage to win the lottery and that's where the problems start. The three end up dealing with the station manager who finds out about their little scam, a local bookie who also finds out and a hit man who wants in on the action. There are some funny moments but this is a movie you only want to watch when you really have nothing else to do and just want to relax in front of the TV. My advice is buy this movie and archive for a really rainy day.
Lucky 7
I love this movie. It is so funny. This is one of Lisa Kudrow's best movie's ever. She is so cool. I am not a fan of John, but he did a good job. Thank You iTunes.
I watched a short preview of this movie and thought it looked funny so I put it on my iPod to watch during a long road trip. I ended up starting it 3 different times because everytime I tried watching I fell asleep. The first hour was the only part I watched of the movie and finally decided it was just one of those not so great films. I wouldn't recommend it unless someone has absolutely nothing to do on a rainy day.
Viewers Also Bought
- The Last Shot
- Jeff Nathanson
- View in iTunes
- Dr. T & the Women
- Robert Altman
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- Chain of Fools
- Pontus Lowenhielm & Patrick Von Krusenstjerna
- View in iTunes
- Holy Man
- Stephen Herek
- View in iTunes
- Metro
- Thomas Carter
- View in iTunes
- $14.99
- Genre: Comedy
- Released: 2000
- © 2000 Paramount Pictures


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There's no requested posing, no photo shoot set up, no studio to invite these girls to. It's just people with cameras who come across amazing looking women and snap pictures of them so you can sample some of the hottest amateurs from around the world! At Candidography, feel like you're there yourself watching these babes in action, as thousands of candid and amateur pictures and videos await you.
Courtney Taylor is the main attraction in this gallery. Art students join in the spectacle as this huge titted blonde gets fucked, manhandled and disgraced. Rope bondage, riding crop, deep throat, rough sex and humiliation. Check out this unusual event.


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Sound: It breaks my heart to say that, if anything, the sound quality can only be described as poor. But, as with anything, the date that the footage in this film was filmed has to be taken into consideration. The footage in this documentary was filmed on two decent quality portable movie cameras in the late '70s and early '80s. Even with the poor, portable sound quality in mind, the quality of the footage from The Police playing their live sets isnt brilliant but can't exactly be described as bad. Some sound recordings of live bands on video cameras sound worse than awful but this one isn't too bad. If I could use one word to describe the quality of sound, it would be that it is decent, not good, but, at the same time, not bad. I would also like to say that I love some of the Police remixes on this documentary (such as 'I Can't I Can't' and 'Put Out The Red Light'). // 7
Overall Impression: Maybe I am slightly biast, but I love anything to do with The Police, and when this came out, I just had to have it. This documentary takes the veiwer to a place where a fan is restricted to go, behind the scenes. It takes you to the places that most people would litterally kill to get to, and quiet frankly so would I (although I might not go as far as killing). A must-have for any Police fanatic. // 10
belavista man
Sgt. Pepper


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Tampa Sets Handle Record for One Program
Full fields, three graded stakes, and quality horses helped Tampa Bay Downs register record total pari-mutuel handle for one program March 12. More than $12 million was wagered on 12 races.
Full fields, three graded stakes, and quality horses helped Tampa Bay Downs register record total pari-mutuel handle for one program March 12. More than $12 million was wagered on 12 races.
Beverly Anderson and Edward Seltzer's homebred Surgical Strike appears headed to the Spiral Stakes (gr. III) after a come-from-behind victory in the $100,000 John Battaglia Memorial Stakes March 12 at Turfway Park.
A strong push to decouple racing from gaming officially hit the wall with the end of this year's Florida legislative session March 11, but a horsemen's coalition said it fully expects the issue to come up again in 2017.
The New York Racing Association board of directors March 10 voted to support federal legislation that would grant USADA authority over equine medication and testing.
Tom LaMarra and Ellis Starr preview the Tampa Bay Derby (gr. II) featuring Star Hill, Rafting, Destin, Brody's Cause, and Economic Model. Watch Video
Racing returns to Laurel Park March 11 after a more than three-week break as part of a new schedule that will allow the facility to capitalize on its expansive turf course.
The American Quarter Horse Association said it remains committed to addressing misuse of medication in racing but a need for more resources has led it to suspend use of its multiple medication violation system pending review.
Gary Barber's Whatawonderflworld, who thus far has shown an affinity for turf and synthetic surfaces, is among a full field of 3-year-olds entered for the $100,000 John Battaglia Memorial Stakes March 12 at Turfway Park.
Burning Sands Stables' homebred Awesome Gent, who sat just off two dueling leaders for almost a half-mile, took over in the stretch and pulled away to win the $125,000 Jimmy Winkfield Stakes for 3-year-olds at Aqueduct.
With on- and off-track pari-mutuel wagering both up at the halfway point of its 2016 meet, Oaklawn Park has again raised overnight purses, this time by up to $5,000 a race.
Major gambling bills tied to a $3 billion compact with the Seminole tribe were removed from a Florida Senate committee agenda March 1 and may not be addressed before the current legislative session ends.
Pro-racing lawmakers in West Virginia took part in a March 1 Capitol press conference to discuss the economic impact of Thoroughbred racing and breeding given legislation that would decouple live racing from gaming.
Legislation that would allow most pari-mutuel operations to end live racing and become slot-machine casinos or card rooms with simulcast wagering easily cleared the Florida House Finance and Tax Committee Feb. 29.
Racing interests and their legislative representatives plan a rally March 1 at the West Virginia Capitol in Charleston to combat bills that call for the decoupling of live racing from gaming.
The Illinois Thoroughbred Horsemen's Association said it believes it can find common ground with Arlington as it moves into contract negotiations and also work with track officials to better position Illinois racing.
A state group that studies the impact of tax changes in Florida offered a general assessment Feb. 26 that decoupling horse racing from gaming would have minimal effect on pari-mutuel revenue for state government.
The West Virginia Senate Feb. 25 had first reading on legislation that would defund and decouple greyhound racing from gaming but maintain requirements that Thoroughbred racing receive its share of gaming revenue.
The AAEP has identified areas it believes are central to understanding exercise-induced pulmonary hemorrhage, and it hopes they determine future research into alternative methods of combating EIPH.
Legislation designed to modernize horse racing in Pennsylvania was signed into law Feb. 23 by Gov. Tom Wolf, who last fall threatened to shut down the industry because it couldn't pay for regulation.
The Maryland Racing Commission Feb. 22 gave the go-ahead to the Maryland Jockey Club to operate an off-track betting parlor at the Maryland State Fairgrounds in Timonium.
It remains to be seen whether the connections of Shogood will attempt to stretch him out around two turns for his next start, but on Feb. 20 he had little trouble winning the 6 1/2-furlong WEBN Stakes at Turfway Park.
Trainer Wesley Ward continued his roll at the Turfway Park winter/spring meet the evening of Feb. 19 with three victories, including the returning group II-winning filly Acapulco.
The Racing Medication and Testing Consortium Feb. 19 issued an overview of its procedures in setting withdrawal times and drug-testing threshold levels after the National HBPA said it would pursue its own research.
The Kentucky Thoroughbred Breeders' Incentive Fund paid out more than $10.5 million to eligible horses based on 2015 races, and the number of mares nominated to the program continues to increase.
Though Gainesway stands Tapit, the leading sire who commands the highest North American stud fee, and brought Empire Maker back from Japan for 2016, the farm is all in on Karakontie, who shares several ties with Kingmambo.
The Breeders' Cup World Championships at Keeneland last year fueled double-digit tourism growth in Lexington in 2015, VisitLEX said Feb. 17.
The Florida Senate Regulated Industries Committee Feb. 17 passed two pieces of legislation, one authorizing a compact with the Seminole tribe and another that would allow decoupling at most racetracks in the state.
Trainer Tom Amoss said the field for the Feb. 20 Risen Star Stakes (gr. II) at Fair Grounds is one of the deepest he has seen at the Louisiana track, and he believes that's good for Mo Tom, who he trains for G M B Racing.
Samuel Henderson's Suddenbreakingnews, last of 14 heading into the far turn, rallied strongly in the stretch to win the $500,000 Southwest Stakes (gr. III) Feb. 15 at Oaklawn Park.
Green Gratto, who has become a force in the New York sprinter ranks in the fall and winter, is among nine horses entered for the $250,000 General George Stakes (gr. III) Feb. 15 at Laurel Park.
Legislation that would remove the requirement that racetracks with gaming also offer live racing has been introduced in the West Virginia Senate.
Two prominent employees of the New York Racing Association are leaving their positions in February. Director of communications John Durso Jr. and chief security officer George Venizelos have taken private-sector jobs.
Tom LaMarra recaps Day 2 of the 2016 Fasig-Tipton Kentucky Winter Mixed Sale, including comments from Fasig-Tipton President Boyd Browning and Gainesway manager Neil Howard. Sponsored by Taylor Made Sales Agency. Watch Video
Florida horse racing and breeding interests made their case against decoupling Feb. 9 during a House Regulatory Affairs Committee meeting, but lawmakers voted to move the legislation forward.
An organization formed to represent the interests of racetrack veterinarians has become proactive in the area of research into therapeutic medications and continues to make its case that vets should be part of drug reform.
The National HBPA Feb. 6 said it plans to help fund research to develop administration and testing guidelines that could be incorporated into the Controlled Therapeutic Medication Schedule.
In the wake of bills introduced in the Florida legislature, horsemen have reiterated their opposition to any measure that would permit pari-mutuel facilities to end live racing but maintain gaming operations.
Achieving true uniformity in equine medication and testing goes well beyond basic adoption of model rules, according to attorneys, horsemen, and veterinarians who picked apart the current system Feb. 5.
The ARCI plans an industry congress for the end of this year to develop consensus on equine medication and testing given its belief Congress won't be anywhere close to acting on legislation introduced last year.
An anti-doping task force in Ireland has issued recommendations designed to combat use of illegal drugs in racing and breeding and strengthen testing programs.
The impact big bettors have on pari-mutuel handle and the resulting revenue, as well as the need to recognize that horse owners are bettors, too, was the focus of a Feb. 4 forum during the National HBPA convention in Florida.
Calls for unity in moving the horseracing industry forward kicked off the National Horsemen's Benevolent and Protective Association convention Feb. 4 in Clearwater Beach, Fla.
Former Kentucky Gov. Steve Beshear, in comments that helped kick off the Consignors and Commercial Breeders Association symposium Feb. 2, said horse racing and breeding in the state is strong, but challenges remain.
Melissa Cantacuzene's The Pickett Factor, winner of the Louisiana Classic Stakes in his last start, returns to action Feb. 6 for the $200,000 Louisiana-bred Premier Night Championship Stakes at Delta Downs.
Legislation that would restore video lottery terminal-generated purse funds that have been diverted to pay down a workers' compensation debt has been introduced in the West Virginia House of Delegates.
The 2016 Ohio Thoroughbred Race Fund will be worth $5.79 million, up 4.2% from last year under a proposal approved by the Ohio State Racing Commission Jan. 26.
Production of quality horse feed has evolved into a combination of natural ingredients and science. And just because a product is widely accepted doesn't mean it's not under regular review.
Mountaineer Casino, Racetrack & Resort has released its 2016 racing schedule and, as was the case last year, the West Virginia track will offer 160 programs.
The Illinois Thoroughbred Horsemen's Association Jan. 24 said proposed changes in state racing regulations, as well as another rule that allows racetracks to "recapture" purse money, "threaten to crush" horse racing.
Laurel Park has canceled its live racing program for Jan. 25, but not because of the about 30 inches of snow that fell on the racing surface over the weekend.