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Conventional protocols for differentiating human induced-pluripotent stem cells (hiPSCs) into smooth-muscle cells (SMCs) can be inefficient and generally fail to yield cells with a specific SMC phenotype (i.e., contractile or synthetic SMCs). Here, we present two novel hiPSC-SMC differentiation protocols that yield SMCs with predominantly contractile or synthetic phenotypes. Flow cytometry analyses of smooth-muscle actin (SMA) expression indicated that ~45% of the cells obtained with each protocol assumed an SMC phenotype, and that the populations could be purified to ~95% via metabolic selection. Assessments of cellular mRNA and/or protein levels indicated that SMA, myosin heavy chain II, collagen 1, calponin, transgelin, connexin 43, and vimentin expression in the SMCs obtained via the Contractile SMC protocol and in SMCs differentiated via a traditional protocol were similar, while SMCs produced via the Sythetic SMC protocol expressed less calponin, more collagen 1, and more connexin 43. Differences were also observed in functional assessments of the two SMC populations: the two-dimensional surface area of Contractile SMCs declined more extensively (to 12% versus 44% of original size) in response to carbachol treatment, while quantification of cell migration and proliferation were greater in Synthetic SMCs. Collectively, these data demonstrate that our novel differentiation protocols can efficiently generate SMCs from hiPSCs.
Citation: Yang L, Geng Z, Nickel T, Johnson C, Gao L, Dutton J, et al. (2016) Differentiation of Human Induced-Pluripotent Stem Cells into Smooth-Muscle Cells: Two Novel Protocols. PLoS ONE 11(1): e0147155. doi:10.1371/journal.pone.0147155
Editor: Gangjian Qin, Northwestern University, UNITED STATES
Received: September 23, 2015; Accepted: December 29, 2015; Published: January 15, 2016
Copyright: © 2016 Yang et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
Data Availability: All relevant data are within the paper.
Funding: This work was supported by National Institute of Health RO1 HL67828; National Institute of Health RO1 HL95077; National Institute of Health RO1 HL114120; and National Institute of Health UO1 HL100407.
Competing interests: The authors have declared that no competing interests exist.
Human induced-pluripotent stem cells (hiPSCs) can provide a theoretically unlimited number of terminally differentiated cells for use in tissue engineering, drug development, and autologous cell therapy; however, their utility will remain limited (particularly for clinical applications) until efficient, standardized differentiation protocols are developed to satisfy the requirements of Good Manufacturing Practice. Protocols for differentiating hiPSCs into endothelial cells (hiPSC-ECs) [1] and cardiomyocytes (hiPSC-CMs) [2] have recently been improved, but conventional methods for generating hiPSC-derived smooth-muscle cells (hiPSC-SMCs) can take longer than four weeks [3] and may rely on co-culturing with feeder cells, which can lead to xenogenic contamination [4].
Because smooth muscle cells (SMCs) develop from a wide range of embryonic tissues, including the neural crest [5], the paraxial/somatic mesoderm [6], the lateral plate mesoderm [7], and the secondary heart field [8], many hiPSC-SMC differentiation protocols direct the cells toward an intermediate, origin-specific lineage [9, 10] before inducing the terminal SMC phenotype. Furthermore, somatic SMCs display a wide range of morphological and functional characteristics that are best described as a spectrum bounded by predominantly synthetic and contractile phenotypes [11]. Here, we present two hiPSC-SMC differentiation protocols. Both protocols begin by using a GSK inhibitor (CHIR99021) and bone morphogenic protein 4 (BMP-4) to direct the hiPSCs toward the mesodermal lineage; then, Synthetic hiPSC-SMCs are produced by culturing the cells with vascular endothelial growth factor (VEGF) and fibroblast growth factor (FGF), or the Contractile hiPSC-SMC phenotype is induced with varying combinations of platelet-derived growth factor (PDGF), transforming growth factor (TGF), and FGF. Each protocol can be completed in two to three weeks and includes a 4- to 6-day selection period, which yields SMC populations that are ~95% pure and remain phenotypically stable for at least 20 generations.
Cell lines
The differentiation protocols were tested with hiPSCs that had been reprogrammed from human cardiac fibroblasts [12] or from human dermal fibroblasts [1] (GriPS, kindly provided by Dr. James Dutton, University of Minnesota, USA) and with H9 embryonic stem cells [13] (ESCs) (kindly provided by Dr James Thomson, University of Wisconsin, Madison, USA). Control assessments were performed with hiPSC-SMCs that had been differentiated via a conventional protocol [14] and in primary human aortic SMCs (HA-SMCs) (Life Technologies Corporation, Grand Island, NY, USA).
Synthetic and contractile hiPSC-SMC differentiation protocols
hiPSCs and ESCs were cultured in mTeSRTM medium on Matrigel-coated plates, with daily medium changes, until confluent (~2 days); then, differentiation into mesodermal-lineage cells was initiated on Day 0 by culturing the cells with CHIR99021 (5 μM) and BMP-4 (10 ng/mL) in RPMI1640 medium and 2% B27. Differentiation into Synthetic SMCs or Contractile SMCs began on Day 3. Synthetic SMCs were produced by culturing the cells with 25 ng/mL VEGF-A and FGFβ in RPMI1640 and 2% B27 minus insulin from Day 3 to Day 7, with 25 ng/mL VEGF-A and FGFβ in RPMI1640 and 2% B27 from Day 7 to Day 9, and with 10 ng/mL PDGFβ and 3 ng/mL TGFβ in RPMI1640 and 2% B27 from Day 10 to Day 14. Contractile SMCs were produced by culturing the cells with 25 ng/mL VEGF-A and FGFβ in RPMI1640 and 2% B27 minus insulin from Day 3 to Day 7, and with 5 ng/mL PDGFβ and 2.5 ng/mL TGFβ in RPMI1640 and 2% B27 from Day 7 to Day 14. The differentiated cells were enriched for SMCs by maintaining them in 4 mM lactate RPMI1640 metabolic medium for 4 to 6 days (Fig 1).
hiPSCs and ESCs were cultured in mTeSRTM medium on Matrigel-coated plates, with daily medium changes, until confluent (~2 days); then, differentiation into mesodermal-lineage cells was initiated on Day 0 by culturing the cells with CHIR99021 and BMP-4 in RPMI1640 medium and 2% B27. Differentiation into Synthetic SMCs or Contractile SMCs began on Day 3. Synthetic SMCs were produced by culturing the cells with VEGF-A and FGFβ in RPMI1640 medium and 2% B27 minus insulin (B27–) from Day 3 to Day 7, with VEGF-A and FGFβ in RPMI1640 and 2% B27 (with insulin) from Day 7 to Day 10, and with PDGFβ and TGFβ in RPMI1640 and 2% B27 from Day 10 to Day 14. Contractile SMCs were produced by culturing the cells with VEGF-A and FGFβ in RPMI1640 and 2% B27– from Day 3 to Day 7, and with PDGFβ and TGFβ in RPMI1640 and 2% B27 from Day 7 to Day 14. Purification was performed by maintaining the differentiated cells in 4 mM lactate RPMI1640 metabolic medium for 4 to 6 days.
Quantitative real time polymerase chain reaction (QRT-PCR)
Total RNA was extracted with RNeasy Mini as directed by the manufacturer's instructions (QIAGEN). cDNA was prepared with a Maxima First Strand cDNA Synthesis Kit (Thermal Scientific Inc), and the QRTPCR mixtures were prepared with SYBR Green PCR Master Mix (Thermal Scientific Inc). QRTPCR reactions were performed on a 7500 Fast Real-time PCR System (Applied Biosystems) and by using the Quantitation-comparative CT setting. The QRTPCR thermal cycling program included 40 cycles, and each cycle consisted of enzyme activation for 2 min at 95°C, denaturation for 30 sec at 95°C, annealing for 30 sec at 60°C, and extension for 30 sec at 70°C; primer sequences are listed in Table 1. Duplicate measurements were performed for each analysis and were normalized to the endogenous level of glyceraldehyde-3-phosphate dehydrogenase (GAPDH) mRNA.
Immunofluorescent imaging and flow cytometry
For immunofluorescent imaging, adherent cells were fixed, permeabilized, blocked with 5% donkey serum, and incubated with primary antibodies at 4°C overnight; then, the primary antibodies were labeled with fluorescent secondary antibodies (Jackson Lab, USA) (Table 2), cell nuclei were labeled with DAPI, and the cells were imaged under an Olympus 200M microscope. For flow-cytometry analyses, cells were fixed with 4% paraformaldehyde for 10 min and incubated with UltraV (Thermo Scientific, USA) block for 7 min at room temperature; then, the cells were labeled with primary phycoerythrin (PE)-conjugated or allophycocyanin (APC)-conjugated anti-SMA antibodies and with isotype-control antibodies (BD Pharmingen, USA) for 30 min at 4°C in phosphate-buffered saline (PBS) and 2% fetal bovine serum (FBS), washed with 2% FBS/PBS, and re-suspended in 0.3 mL 2% FBS/PBS containing 5 μL of propidium iodide (10 μg/mL). Flow-cytometry analyses were performed with a FACS Aria instrument (BD Biosciences, USA), and control assessments were performed with undifferentiated hiPSCs.
Cell migration
Cells were cultured in 6-well plates (4×105 cells/well) overnight at 37°C in Dulbeco's Modified Eagle Medium (DMEM) containing 10% FBS under a water-saturated, 5% CO2 atmosphere; then, the cultures were scratched with a 200-μL pipette tip and the medium was changed to DMEM containing 1% FBS. Images were taken 10 hours later, and cell migration was quantified as the number of cells present in the scratched region.
Cell contraction test.
Cells were seeded onto a gelatin-coated 6-well plate (2×105 cells/well), partially detached by incubating them with a non-enzymatic dissociation buffer (Versene, Invitrogen, USA), and then treated with 10 μM carbachol for 5 min. Images were obtained both 0 and 5 min after carbachol treatment, and contraction was evaluated by using CellC Software (Department of Signal Processing, Tampere University of Technology, https://sites.google.com/site/cellcsoftware/download) to measure the cells' cross-sectional surface areas.
Gel contraction test.
SMCs (1×106) were suspended in 250 μL of an 8 mg/mL fibrinogen solution; then, the cell-containing fibrinogen solution was mixed with 250 μL of a 5 U/mL thrombin solution in one well of a 24-well plate and incubated at 37°C. Ten min later (after the mixture had formed a semi-solid gel) the gels were transferred to a 6-well plate and cultured with 300 U/mL aprotinin and 10 μM Rho kinase (ROCK) inhibitor (Y-27632; Millipore, USA) in 2 mL DMEM containing 5% PBS. Gel sizes were measured at 24-hour intervals over 3 days.
Cell proliferation
SMCs (1×106 cells/mL in RPMI1640) were serially diluted in a 1:2 ratio, and 100 μL of solution for each cell concentration was added to the wells of a 96-well plate. The cells were cultured with PDGFβ and TGFβ in DMEM containing F12 and 5% FBS for 2 hours under 5% CO2; then, 20 μL of One Solution Cell Proliferation Assay reagent (Promega, USA) was added to the well, and the cells were cultured under the same conditions for another 90 min. Proliferation was quantified by measuring optical density at 490 nm with an ELISA reader (Energy H2, Bio-Tek instrument, USA) both before (i.e., at 0 min) and after the 90-min culture period; measurements were blanked with the One Solution Cell Proliferation Assay reagent, and the measurement at 0 min was used to define the baseline.
Data are presented as mean±standard deviation (SD) and were evaluated for significance via the student T test (unpaired, 2 tailed); the Bonferroni correction was used when more than two groups were being compared. Statistical analyses were performed with SPSS software (version 20.0; IBM, Armonk, New York, USA) and a p-value of less than 0.05 was considered significant.
Differentiation of hiPSCs into hiPSC-SMCs
The efficiency of our differentiation protocols was evaluated in cardiac-lineage hiPSCs (chiPSCs), dermal-lineage hiPSCs (dhiPSCs), and embryonic stem cells (ESCs). The cells were incubated on Matrigel-coated plates for two days until they reached near-complete confluence. Differentiation into the mesodermal lineage was initiated on Day 0 and produced cultures of uniform morphology with a small amount of cell death (10%~15%) that can likely be attributed to CHIR99021 toxicity. Induction of the SMC phenotypes began on Day 3, and then the differentiated cells were purified by maintaining them in metabolic medium for 4 to 6 days beginning on Day 14 (Fig 1). Before purification, flow cytometry analyses indicated that SMA was expressed by ~45% of chiPSC-derived SMCs (Synthetic: 46%, Contractile: 44.5%; n = 6) (Fig 2), by 35% (Contractile; n = 3) to 75% (Synthetic; n = 3) of dhiPSC-SMCs, and by ~80% (Synthetic: 83%, Contractile: 78%; n = 3) of hESC-derived SMCs. The proportion of SMA+ cells increased to ~95% after purification (chiPSC-SMCs, Synthetic: 95.1%, Contractile: 94.5%; n = 6. dhiPSC-SMCs, Synthetic: 97%, Contractile: 96.4%; n = 3. hESC-SMCs, Synthetic: 98%, Contractile: 98.6%; n = 3).
The efficiency of the differentiation protocols was evaluated via flow cytometry analyses of SMA expression in (A) undifferentiated cardiac-lineage hiPSCs (chiPSCs) and in (B-C) chiPSC-SMCs obtained via the (B) Synthetic and (C) Contractile SMC differentiation protocols before and after purification.
Characterization of Synthetic and Contractile hiPSC-SMCs
The specificity of the two hiPSC-SMC differentiation protocols was evaluated by comparing the expression of cell-specific markers in chiPSC-derived Synthetic and Contractile SMCs, in hiPSC-SMCs that were generated via conventional differentiation methods, and in primary human aortic SMCs (HA-SMCs). Myosin heavy chain 11, calponin, and transgelin mRNA levels in conventional hiPSC-SMCs and Contractile chiPSC-SMCs were similar and significantly higher than in Synthetic chiPSC-SMCs (Fig 3A), but Synthetic chiPSC-SMCs were more likely to express collagen 1, connexin 43, or vimentin (Fig 3B). Assessments of cell migration (Fig 4A) and proliferation (Fig 4B) were also significantly greater in Synthetic chiPSC-SMCs than in Contractile chiPSC-SMCs, but the two-dimensional surface area of Contractile chiPSC-SMCs declined more extensively in response to carbachol treatment (Fig 4C and 4D). Gels containing Contractile chiPSC-SMCs also contracted to 27% of their original size, compared to 46% for gels that contained Synthetic chiPSC-SMCs (Fig 4E).
(A) mRNA levels of the SMC markers alpha smooth-muscle actin 2 (αSMA-2), smooth muscle myosin heavy chain 11 (MHC-11), calponin (Calp), vascular-endothelial cadherin (VE-Cad), and transgelin (Tgln) were evaluated via quantitative RT-PCR and normalized to endogenous GAPDH mRNA levels (*p<0.01 vs Conventional or Contractile chiPSC-SMCs, †p<0.05 vs Conventional chiPSC-SMCs, †p<0.01 vs Contractile chiPSC-SMCs). (B) Smooth-muscle actin (SMA), collagen I (Col I), connexin 43 (Cnx 43), vimentin (Vmt), and calponin (Calp) protein expression (red) was detected via immunofluorescent staining in human aortic SMCs, in chiPSC-SMCs that were obtained via a conventional differentiation protocol, and in chiPSC-SMCs obtained via our Synthetic or Contractile hiPSC-SMC differentiation protocols; nuclei were counterstained with DAPI (blue) (bar = 100 μm).
(A) 4×105 Synthetic or Contractile chiPSC-SMCs were cultured on gelatin-coated plates for 24 hours; then, the plate was scratched with a 200-μL pipette tip, and images of the scratched area were obtained 0 and 10 hours later. Migration was quantified by counting the number of cells that had migrated into the scratched area (*p<0.01). (B) 1×106/mL Synthetic or Contractile chiPSC-SMCs were suspended in 100 μL of RPMI1640 and cultured in the presence of PDGFβ or TGFβ for 90 min; then, the solutions were serially diluted in half six times, and cell concentrations were evaluated via optical density measurements at 490 nm (*p<0.01). (C) 2×105 Synthetic or Contractile chiPSC-SMCs were cultured on gelatin-coated plates for 24 hours; then, the cells were treated with carbachol to induce contraction, and images were obtained 0 and 5 min later. (D) Contraction was evaluated by calculating the mean cell surface area at each of the two time points (*p<0.01). (E) 1×106 Synthetic or Contractile chiPSC-SMCs were suspended in a fibrinogen gel; then, the gels were cultured with aprotinin and Rho kinase inhibitor, and the surface area of the gels was measured 0 and 3 days later (*p<0.01).
Although the contractile activity of SMCs may be their most prominent characteristic, SMCs also contribute to a variety of other physiological activities, including the growth and remodeling of vessels in response to vascular injury, exercise, or pregnancy [15]. The functional diversity of SMCs is accompanied by considerable phenotypic diversity, ranging from contractile cells at one extreme to predominantly synthetic cells at the other. These two archetypal SMC phenotypes differ substantially in morphology, marker expression, and activity, including their rates of proliferation and migration. Thus, the utility of hiPSC-derived SMCs for a particular application may depend on the specific phenotype generated. For example, pharmacological studies of vasoconstriction may be best performed with populations of primarily contractile SMCs, while tissue engineering [9, 10, 16–19] and cell therapy could benefit from the inclusion of synthetic SMCs, which are more proliferative and produce larger amounts of extracellular matrix material [20].
A number of highly efficient hiPSC-SMC differentiation protocols have been developed [14, 21, 22], but methods for specifying the contractile or synthetic SMC phenotype have been unavailable until recently [23, 24]. The results presented here indicate that our novel differentiation protocols effectively direct hiPSCs toward either a contractile or synthetic SMC phenotype, and that the SMC populations can be purified to ~95% via metabolic selection. Furthermore, the risk of xenogenic contamination is minimized, because the differentiation and purification procedures do not require exposure to feeder cells, and the entire protocol (both differentiation and purification) can be completed in just 2–3 weeks. The cells can also be quickly expanded in DMEM with 5 ng/mL FGF and 5% serum or Medium 231 (Life Technologies, USA), and the SMC phenotype remains stable for at least four months or 20 generations when the cells are maintained in 5% FBS or RPMI-1640 medium with B27. Proliferation can be halted by limiting the serum concentration or by reducing the cell density to ~10% or less (e.g., 5×104 cells/well in a 6-well plate).
The predominant phenotype of an hiPSC-SMC population can be characterized by evaluating the expression of a panel of cell-surface markers [23]. Marker expression in SMCs generated via our Contractile SMC differentiation protocol was similar to the expression in conventionally produced hiPSC-SMCs, while the synthetic SMC differentiation protocol yielded cells that produced more of the extracellular matrix proteins collagen 1 and connexin 43. These observations are consistent with the results from studies with primary SMCs that have been isolated from swine coronary arteries [25, 26], although the pattern of gene expression appears to vary depending on whether the cells are studied in vivo or in vitro [11, 27]. Furthermore, some evidence suggests that marker expression in SMCs derived from hiPSCs and hESCs, or from hiPSCs that were generated from different somatic tissues, can also differ [23, 24]. Thus, the efficiency of our hiPSC-SMC differentiation protocols and subsequent function of the differentiated cells may depend on which hiPSC (or hESC) line is used.
In conclusion, we have developed two novel, highly efficient differentiation protocols that can be used to generate contractile or synthetic SMCs from hiPSCs in just 2–3 weeks while minimizing the risk for xenogenic contamination.
The authors would like to thank W. Kevin Cukier-Meisner, PhD, ELS, for his editorial assistance with this manuscript.
Author Contributions
Conceived and designed the experiments: LY JZ. Performed the experiments: LY ZG TN CJ LG JD CH. Analyzed the data: LY CH. Contributed reagents/materials/analysis tools: LY JZ. Wrote the paper: LY JZ.
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2 identical bra tops from VS. Both have a banded bottom so it's forgiving around the middle. Listed together to save on shipping.
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Mon 12/12/16 - Fri 12/16/16 (4-8 days)
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text:
Our Mission
Thanks to you, $127,404 has been donated to charitable organizations dedicated to saving elephants
In 2014, The Elephant Pants embarked on a mission to help save elephants - and feel good while doing it.
Our Story
In 2014, two friends found themselves looking up at an elephant and something clicked. Standing there, staring up at the gentle giant, they realized just how special elephants were. They understood why elephants had been revered for thousands of years and why so many people traveled far and wide to see them. They also became aware of the dangers of being such a special animal and learned about the consequences of human-elephant conflict. After Traveling home, wearing the pants that had become such a staple during their trip, they found themselves troubled. Something had to be done. The Elephants had to be saved. So they embarked on a journey to help save elephants and feel damn good about it one pair of pants at a time.


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Blood Gulch (disambiguation)
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Blood Gulch could refer to:
- Blood Gulch - A famous Halo: Combat Evolved multiplayer map.
- Blood Gulch (Halo Wars level) - The Halo Wars remake of the original Halo: Combat Evolved map.
- Coagulation - The Halo 2 remake of the original Halo: Combat Evolved map.
- Bloodline - The Halo 2: Anniversary remake of the Halo 2's Coagulation.
- Hemorrhage - The Halo: Reach level remake of the original Halo: Combat Evolved map.
- The Blood Gulch Chronicles - The first 5 seasons of Red vs. Blue
- This is a disambiguation page - a navigational aid which lists other pages that might otherwise share the same title. If an article link referred you here, you might want to go back and fix it to point directly to the intended page.


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They'll now play Bristol, Brighton, Glasgow, Leeds and London in January.
Beach Slang's Ruben Gallego releases statement about departure from band
Beach Slang: "When we play live it's an exorcism."
Beach Slang have had their ups and downs, but with a new album influenced by Britpop, what else would you expect?
Beach Slang – A Loud Bash Of Teenage Feelings
Stream Beach Slang's new album in full
'A Loud Bash Of Teenage Feelings' is due next week.
Hear Beach Slang cover Japandroids for new Polyvinyl compilation
The twenty-song release is out on 25th November.
Against Me! front up September's new issue of Upset, out now
It's on the streets today. Order a copy or read it online now.
Beach Slang drop new video for 'Atom Bomb'
Drop? Bomb? Geddit?
Beach Slang announce four UK headline dates for November
They'll play Glasgow, London, Leeds and Brighton.
Beach Slang punch Reading Festival right in the heart
Does exactly what it says on the tin.
Beach Slang stream 'Punks In A Disco Bar' video
The clip is for the first track from their new album 'A Loud Bash Of Teenage Feelings'.
Drummer JP Flexner leaves Beach Slang
The band are currently working on their second album.
Beach Slang aren't breaking up
The rumours of their demise have been greatly exaggerated. Kinda.
Beach Slang announce June UK dates
Waves and Muncie Girls are supporting on the run.
Beach Slang have started work on their second album
The band told us earlier this year they wanted it out in 2016.
Circa Survive, Beach Slang and more cover Nirvana on 'Bleach' tribute
You can get a first taster in the form of Circa Survive's cover of 'Love Buzz'.
Beach Slang want a new album out this year, 'FYI'
"We have a US tour this April and I want to record it before we split for that."
The Valentine's Day Mixtape: Beach Slang
From Beach Slang, with love.
Panic! At The Disco, All Time Low, SWMRS and more – February's Upset is out now
Inside the new issue, out now, we get inside the mind of Panic! At The Disco's crazy genius Brendon Urie.
Beach Slang plot US tour for April and May
The band are touring in support of new album, 'The Things We Do To Find People Who Feel Like Us'.
Panic! At The Disco, All Time Low, Bury Tomorrow and more – it's February's Upset
Inside the new issue, out next Wednesday (10th February), we get inside the mind of Panic! At The Disco's crazy genius Brendon Urie.


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Abner McGehees, Charles Frederick Briggs, Clement Briggs, Contential Army, Edmund Bridges, Edmund Briggs, George Nixon Briggs, Governor Winslow, Henry Brigs, Hinham MA, Joan Allen, John Briggs, June Gilmer, King Phillips War, Matthias Briggs, MeGehee fmily, Name variations colonial records, Nathaniel Dunn, Newport Rhode Island, Robert Dunn, Scituate MA, Ship Blessing 1635, Virginia, Walter Briggs
Came across this article published in the newspaper. Various spellings Brigges, Brigs, Bridges, Brug, and Brygges. Sharing with Group New England Genealogy and History Group.
Further Reading Briggs Family of America by Samuel Briggs published 1880 Also check out Briggs Genealogy Page


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The NT Labs Pondlab 200 Multi Test Kit carries out over 200 tests of 6 different parameters, giving reliable, steadfast results and of course great value for money. Well known for their expertise in all things aquatic, NT Labs offer top quality pond equipment for a beautiful, healthy pond.
The pack includes everything you might need to conduct a professional test; full instructions, vials, testing reagents and more. A colour gauge is also included to compare the results quickly and easily.
Tests for:
The pack includes:
|NT Labs Pondlab 200 Multi Test Kit
|200 Tests


text:
Sound: This wasn't by any means the best Bon Jovi performance ever. The amp settings sounded off, and Jon Bon Jovi repeatedly struggles to hit notes. The tracks on the album however, which include the full Lost Highway album, do sound more country than ever before.
Bon Jovi claim that the album 'Lost Highway', wasn't written for financial purposes, instead coming from the bands creative freedoms. They constantly refer to the factors which helped them write the album, and despite the occasional failures musically throughout the DVD, its easy to see that they were being 100% truthful.
The records played are truly brilliant compilations of Country Music with a rock sound. These tracks pretty much led to the sound that is currently used by the likes of 'Taylor Swift' and country legend, 'Alan Jackson'. It was also nice to see Jon Bon Jovi play guitar, something he only seems to do once every three albums.
The more you watch the concert, the less annoying it is. // 7
Overall Impression: At the time of realise no music sounded like the Lost Highway album. It was a one off. Now almost all country music sounds like it, which is only a good thing. The DVD is very impressive. The concert is one that you watch once, don't like, then realise that a week later your hooked on the songs and need to listen to it once again. Then your hooked from that point. I like almost the whole DVD, its so different. What I don't particularly like is the amp setting used by Sambora for most of the first four or five songs.
If I were to loose this DVD, I'd buy it again. And before I finish this review, I must praise the violinest on the DVD, for two brillaint lyrical performances. // 8


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Free personalized radio that
plays the music you love
Bali Run
Features of This Tracksmooth jazz elements
block piano chords
a lively electric guitar solo
electric bass playing
an interesting song structure
interesting harmonic progressions
interesting part writing
strong melodies
a groove oriented approach
elaborate arrangements
minor tonality
These are just a few of the hundreds of attributes cataloged for this track by the Music Genome Project.show more
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Loreto Bay 3 Bedroom Casa Poema(9 Reviews)
The owner has been emailed.
To book this property, you need to complete your booking through checkout on the VRBO website. We can't protect your payment if we don't know you've booked through us. Learn more
- Minimum stay:1-4 nights
- Sleeps:6
- Bedrooms:3
- Bathrooms:3
- Property type:Villa
- Internet:Yes
- Pets considered:Yes
- Wheel chair accessible:No
About the Property
Poema Style Home
Our property manager Arturo will help you get settled into the Loreto Bay lifestyle, the restful and relaxing Villages of Loreto Bay. Surrounded by the Sierra de la Giganta mountain range and the Sea of Cortez, Loreto Bay is located in the charming town of Nopolo. The town of Loreto is just minutes away, as is the airport with connecting flights to Los Cabos, Los Angeles, and Calgary.
Upon arrival you, our guests, will step into a special place. From the large, palm-treed courtyard, open the French doors to your casa & our lovely, well-equipped, three bedroom, three bathroom villa home. The main floor includes kitchen/dining area, living room, main bedroom with king bed, and bathroom with shower. The courtyard garden is just out two sets of French doors, and where you will find the second bedroom / bath, a mirror image of the main bedroom / bath. Upstairs on the terrace is the private, master king suite, overlooking the gardens and leading up to the viewing tower which boasts 360 degree views of Loreto Bay: golf course, mountains, sea, and unending charm
Take a five-minute stroll to the beach and the Inn at Loreto Bay for restaurants, snorkeling, kayaking, and more. Wander along the boulevard or 'paseo' and visit the wine bar, café, designer shops, hair/massage/nail salon, or community center.
Our property manager Arturo is fluent in English, and is at your service to make your stay at our Casa your #1 choice in Loreto. Contact us for your best long-term deal here in Loreto Bay! Stay the summer or longer.
All bedrooms and living room have independent AC, ceiling fans, TVs, DVD players, and WiFi/Ethernet. There is a built-in safe in the living room and laundry next to the kitchen for your use. All linens and towels are provided, as are all kitchen dishes, etc.
New in 2016 - Last month, VRBO began rolling out a new service fee to be charged to travelers who book on HomeAway, VRBO, and VacationRentals.com. The new service fee is a percentage-based fee of 4–9% (average 6–7%) based on total rental price. The fee is collected during the checkout process.
We wanted to be sure you're aware of this new fee, and to share with you why we offer alternative payment options such as personal check and PayPal.
When you're ready to book, here are some tips to keep in mind.
Paying with a credit card on VRBO protects your payment for up to $10,000 against listing fraud. We recommend completing your booking on VRBO.Learn more
Member since: 2009
Property Type
- Villa
- 2100 sq. ft.
Accommodation Type
- Vacation Rental
- Guests Provide Their Own Meals
- Long-Term Renters Welcome
Minimum Age Limit For Renters:
Minimum renter age (unaccompanied) is 25 years of age...moreless
- Children Welcome
- Non Smoking Only
Bedrooms: 3 Bedrooms, Sleeps 6, Beds for 6
- Master: 1 king
- Main: 1 king
- Garden: 1 king
- Master bedroom is located on the terrace level, above the gardens. It has an ensuite bathroom with shower, extra large tub, and two sinks. There are also two amoires for clothing, a writing table, TV and DVD player, AC, and love seat in the bedroom area. Garden bedroom is located on the ground level just off the gardens. It also has an ensuite bathroom with shower. The bedroom has a clothing amoire, TV and DVD player, and AC. The main bedroom is located in the main house and has an ensuite bathroom with shower that is shared with the main living quarters. It too has a clothing amoire, TV and DVD player, and AC....moreless
Bathrooms: 3 Bathrooms
Other Amenities
- Check in time is 2 pm Check out time is 11 am
An extensive 'take one, leave one' library of books and movies are available at the Community Center....moreless
- DVD Player
- Away From It All
- Family
- Romantic
- Sports & Activities
- Health/Beauty Spa
- Marina
- Restaurants
Local Services & Businesses
- ATM/Bank
- Fitness Center
- Groceries
- Hospital
- Massage Therapist
- Medical Services
Leisure Activities
- Beachcombing
- Bird Watching
- Boating
- Eco Tourism
- Paddle Boating
- Photography
- Scenic Drives
- Shelling
- Shopping
- Sight Seeing
- Walking
- Whale Watching
- Wildlife Viewing
Location Type
Golf Course View:
The golf course is about 25 yards from the Casa to the 10th tee. The club house is a walk down the fairway, or a drive a short distance down the Paseo....moreless
- Mountain View
Ocean View:
The beach in Nopolo, Loreto Bay, is located about 100 yards from your Casa. It is a darker sand, not your white sand beaches of the Carribean. The surf is minimal, so not much opportunity for surfin...moreless
- Resort
- Water View
Sports & Adventure Activities
- Cycling
- Deepsea Fishing
- Fishing
- Golf
- Hiking
- Kayaking
- Mountain Biking
- Rock Climbing
- Sailing
- Scuba Diving Or Snorkeling
- Snorkeling
- Snorkeling/Diving
- Sound/Bay Fishing
- Surf Fishing
- Swimming
- Tennis
- Wind-Surfing
- Dining
- Dining Area
- Seating for 6 people
- Air Conditioning
- Clothes Dryer
Fitness Room / Equipment:
Fitness room is available for use at the hotel, just behind Arturo's Rentals on the beach. Yoga is available several times a week at the Community Center on the Paseo....moreless
- Hair Dryer
- Heating
As of May 4, 2016 - we are having issues with our Internet provider and dono' have internet service available in Casa 473 now. We hope to have this corrected soon, please ask when inquiring....moreless
- Iron & Board
- Linens Provided
Dishes & Utensils:
Home comes with all the necessary dishes, pots, pans, and utensils you will need....moreless
- Dishwasher
Kitchen is equiped with an electric range, microwave, dishwasher, and refrigerator....moreless
- Microwave
- Oven
- Refrigerator
- Stove
- Toaster
- Balcony
There are bicycles stored in the garden bedroom for your use....moreless
Fishing and sightseeing boats are available for rent through the hotel or a variety of places in Loreto....moreless
Deck / Patio:
The terrace above the main house has lounging chairs, a dining table and chairs, atop a cantera tile floor inlaid with tortugas and dolphins....moreless
An amazing 18 hole course is located just minutes from your doorstep. Clubs are available to rent at the pro shop. You can buy unlimited golf if you are planing to stay for a few weeks or longer....moreless
Kayak / Canoe:
Kayaks and wake boards are available for rent on the beach in front of the hotel....moreless
Lawn / Garden:
Our casa has a surrounding garden area with a fountain, lounge chairs, citrus trees, and a variety of local vegitation....moreless
Outdoor Grill:
A built-in propane grill is located under the pergola on the terrace for grilling up the catch of the day....moreless
Water Sports Gear:
Scuba diving is available through dive shops in Loreto....moreless
RatesCurrency Conversion
|Weekend Night
|Monthly *
Winter / Spring 2017
Nov 1 - Apr 30, 2017
4 night min stay
Summer 2017
May 1 - Jul 31, 2017
4 night min stay
Fall 2017
Aug 1 - Oct 31, 2017
4 night min stay
Fall 2018
Aug 1 - Oct 31, 2018
4 night min stay
Additional information about rental rates
- Refundable Damage Deposit $250
Check in time is 4 pm
Check out time is 11 am
Refundable $250 deposit due to hold reservation. Full payment due 30 days prior to arrival. Checks and PayPal (funded) accepted.
*Deposit varies based on length of stay and/or pets. Surcharge for any excessive cleaning requirements and/or damage will be deducted from refund.
All inclusive. NO extras!
Owner's cancellation policy:
100% refund if canceled at least 60 days before arrival date.
Don't forget your vacation protection! Get protected now
Adding our Vacation Protection services can make sure your getaway goes smoothly, no matter what. We offer Cancellation Protection and Damage Protection so you can truly relax.
Car: Not Necessary
Owner info
Year Purchased: 2005
About the owner: Our family bought in Loreto Bay 'in the beginning', when the lots were just caulk marks in the sand. It has been a wonderful, always eventful, journey from then until today. The only constant has been the beautiful mountains and sea, friendly people, and great food.
Why the Owner Chose Loreto Municipality, Baja California Sur, Mexico:
We have lived in our casa for the past six years, sharing it with our friends and extended family over the years. We have decided to share our home with others and are now renting our casa so you can create your own memories in Loreto Bay.
Contact us
Send email
- Primary: 907-862-3868
- Click Here to see All My Rental Listings
Loreto Bay Estuary and Golf Course
Golf course view
Shopping under the laurel trees in Loreto
Christmas tree at the hotel
Community pool / hot tub area
Beaches near Mulege (1 hour)
Garden bedroom
Living room
Master bedroom
Terrace BBQ center
Front entrance walkway
Courtyard gardens
Golf course and estuaries
Golf course, #10
City Hall and town square
Villages of Loreto Bay
Sea lions on Isle Coronado
Garden bedroom
Master bath
Master bedroom
Viewing tower, west toward the Sierra de la Giganta
Front view of Casa 406
Lobsters hot off the grill
This listing was first published here in 2013.
Date last modified - Tuesday, December 06, 2016
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The Alamo Heights School Foundation mobilizes community support for current and long-term strategies that enhance and perpetuate district-wide academic opportunity and excellence for our children.
Dianne Hughes
Alamo Heights School Foundation,ahsf
Also Known As
See more addresses
Main Address
7101 Broadway
San Antonio, TX 78209 USA
Fund Raising and/or Fund Distribution (B12)
IRS Filing Requirement
This organization is required to file an IRS Form 990 or 990-EZ.
How does this organization make a difference?
Self-reported by organization
What are the organization's current programs, how do they measure success, and who do the programs serve?
Program 1
AHISD Wellness Program
In its 2009 Strategic Plan, AHISD declared that it was time to "aggressively confront the social and emotional issues of our community". Drug and alcohol abuse is a National problem that reinforces the necessity that our schools address the whole student and issues that surround their choices.
In response, a Wellness Coordinator was hired. For the past three years she has been developing campus programs to provide age appropriate responses and resources relevant to the emotional and social well-being of AHISD students. The Wellness Program focuses on the family to foster better family relationships and much needed honesty in our community in treating emotional and behavioral issues that can lead to drug and alcohol abuse. The goal is to nurture preventative resources that support healthier choices and helps save lives.
AHISD is in the process of creating a new paradigm that could become a model for other school districts and communities. To date, we have received requests from both public and private schools to share information about the program and its intended scope.
Our campaign goal of $1.5 million will endow this program in perpetuity to sustain a program that is already creating a healthier community and saving lives.
Program long term success
Not available
Program success monitored by
Not available
Program success examples
Not available
Population(s) Served
Program 2
Grants to Educators
The Alamo Heights School Foundation's current Grants to Educators program was established in 1998 for educator innovation. The Innovative Grants program awarded AHISD teacher applicants with funds that enable and encourage them to be innovative in their approach to teaching, motivating and inspiring student learning through developing activities or incorporating materials outside normal curriculum or teaching patterns.
In 2009, the AHSF evolved Innovative Grants to the current Grants to Educators program. The guiding criterion for allocating Grants to Educators comes from four focus areas of AHISD's Strategic Plan.
- All Learning will be Engaging, Relevant & Challenging - AHSF supports educator efforts aimed at attaining academic excellence through specific and rigorous academic experiences.
- Closing the Achievement Gap - AHSF supports educator efforts of differentiated instruction in core curriculum to address the varied needs of students.
- Ensuring a High-Performing Faculty and Staff - AHSF recognizes that an integral part of excellence in education is continued educator development, collaboration, and leadership.
- Creating a Culture of Participation that Ensures Equitable Access to Academic (and Extra-Curricular) Activities - AHSF supports projects and programs that further equitable access to academic activities for all students in the AHISD.
In 2012, the AHSF awarded 58 teachers in the district $100,000 worth of grants.
Program long term success
Not available
Program success monitored by
Not available
Program success examples
Not available
Population(s) Served
Program 3
Heights Heroes
Heights Heroes Awards were created in 2009-2010 with the goal to recognize excellent teaching practices by peer nominations in the Alamo Heights Independent School District.
Eligibility: Any member of the AHISD faculty, staff or administration can nominate a teacher/educator for a Heights Hero Award. The review committee seeks to identify those who go "above and beyond" in their teaching and instructional methods - being available, inspiring a class to excel, or making a real difference in the lives of the students are examples. The AHSF Board makes its selections based on those teachers who most closely fit the award criteria.
Amounts: All Heights Heroes Awards shall be in the amount of $500 to be used for the recipient's classroom or school-related project.
Program long term success
Not available
Program success monitored by
Not available
Program success examples
Not available
Population(s) Served
Program 4
Named Funds
In addition to the grants for which teachers apply, there are other grants available that support specific educational opportunities for teachers and students. Some of these funds are endowed to provide for a full program and/or position, while others provide a portion of a program or position.
Part of the important work of the AHSF is to grow the General Endowment for perpetual sustainability of the needs of AHISD. The Alamo Heights School Foundation accepts gifts to endow specific programs and/or positions of importance that align with its mission statement to provide academic excellence. Such gifts would be from $1.5 million upward.
- Glenn R. and Sally Ramsdell Fund
- Teacher for Academic Excellence in Science
- Faye Langley Cowden Chair for Elementary Education
- Johnnie Eng Excellence in Teaching Fund
- Wellness Program
- Rob Boldrick Memorial Award
- Caroline Gose Memorial Grant
- Graham Ladensohn Memorial Lecture Series
- Martha Spoor Young Writers Fund
- The Charles Urschel Guenther Theater Arts Fund
- Ida M. Kennedy Fund for Academic Excellence
- Sarah Chidgey Hughes Shine Bright Fund *
- Paul A. Forester Math Fund *
* Fund currently maturing
Program long term success
Not available
Program success monitored by
Not available
Program success examples
Not available
Population(s) Served
The people, governance practices, and partners that make the organization tick.
Dianne Hughes
Tiffany Mills
GuideStar worked with BoardSource, the national leader in nonprofit board leadership and governance, to create this section, which enables organizations and donors to transparently share information about essential board leadership practices. Self-reported by organization
Does the board conduct a formal orientation for new board members and require all board members to sign a written agreement regarding their roles, responsibilities, and expectations?
Has the board conducted a formal, written assessment of the chief executive within the past year?
Have the board and senior staff reviewed the conflict-of-interest policy and completed and signed disclosure statements in the past year?
Does the board ensure an inclusive board member recruitment process that results in diversity of thought and leadership?
Has the board conducted a formal, written self-assessment of its performance within the past three years?


text:
This Tweet from @alanjhorne has been withheld in response to a report from the copyright holder.
@Andy_russell_93 @jsnboyd he wouldn't do it down south? vine.co/v/MXBwPnPLqFP should go take a long look at yourself.
Hamburger menus on desktop, stop it, just stop it. Not a single piece of data to support it's use, plenty showing you it's bad.
My work may be on the lookout for a middleweight UX/UI designer, based in Glasgow (no remote). Give me a shout if you're interested.
My work are hiring pretty much every type of Dev there is, also have a UX Designer position, all based in Glasgow. If interested, contact me


text:
Hudson Valley Oakdale 6"e 1 Light Wall Sconce in Polished Nickel
Home > 1800lighting.com > Hudson Valley
Like the keystone from which it takes inspiration, Oakdale is at the apex of classic style. Thick beveled-edge mirrors, cut to the storied keystone shape, anchor a look that will dazzle through the ages. 1 Light Wall Sconce in Polished Nickel
Hudson Valley http://www.1800lighting.com/images/jqzoom/hudson valley/330-PN.jpg
On Sale
$250.00 $212.50 at 1800lighting.com


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Be the first to like this
Published on
Social media accounts for 27% of all time spent online, so to say that they are an effective marketing resource would be an understatement. Furthermore, pictures obtain far more interaction than posts with simple text. The combination of these two resources make Pinterest and Instagram valuable assets to multifamily professionals to connect with consumers. Erica Campbell Byrum, real estate social media expert, explains the best practices of using these social sites for growing your real estate business.
This presentation was given at the Apartment Internet Marketing Conference (#AIMConf) on May 5, 2014 by Erica Campbell Byrum, Director of Social Media for Homes.com & ForRent.com.


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Bench Bar Conference Commitee
Bench Bar Conference
Assists in planning and organizing the annual DBA Bench/Bar Conference attended by DBA members and the judiciary.
This committee generally meets the second Wednesday of the month.
Committee Contacts:
Co-Chair & Board Advisor Shonn Brown - firstname.lastname@example.com
Co-Chair Jason Freeman - firstname.lastname@example.com
Co-Chair Coyt Johnston - firstname.lastname@example.com
Co-Chair Dick Sayles - firstname.lastname@example.com
Co-Chair Kimberly Sims - email@example.com
Co-Chair Katie Stepp - firstname.lastname@example.com
Co-Chair Danny Tobey - email@example.com
Co-Chair Clark Will - email@example.com
Co Vice-Chair Stefanie Bradshaw - firstname.lastname@example.com
Co Vice-Chair Quentin Brogdon - firstname.lastname@example.com
Co Vice-Chair Steven Bruneman - email@example.com
Co Vice-Chair David Elrod - firstname.lastname@example.com
Co Vice-Chair Hon. Bonnie Goldstein - firstname.lastname@example.com
Co Vice-Chair Brian Lauten - firstname.lastname@example.com
Staff Liaison Rhonda Thornton - firstname.lastname@example.com


text:
Metropolitan Rectangular Coffee Table
- Overview
Our stylish Metropolitan coffee table adds organization to busy family spaces. Carefully built to last for years to come, it features a compact profile and simple silhouette that make it perfect for smaller spaces.
- Table is crafted of kiln dried solid hardwood and mahogany veneer layered over MDF.
- Apron and legs are crafted of solid rubberwood.
- Finished using an exclusive multistep process that includes staining in Espresso, priming, sanding, glazing, and sealing with lacquer for moisture resistance.
- Legs are wood blocked for structural integrity.
- Adjustable levelers add stability on uneven floors.
- Simple assembly.
- Dimensions & Care
- Overall: 52.5" wide x 22.5" deep x 18.25" high
- Top: 52.5" wide x 22.5" deep x 2.25" thick
- Shelf (1): 49" wide x 19" deep x 1.25" thick
- Clearance Above Shelf: 11"
- Clearance Below Shelf: 3.5"
- Distance Between Legs: 47.25" side to side; 17.25" front to back
- Maximum Weight Capacity (top): 200 pounds
- Maximum Weight Capacity (shelf): 50 pounds
- Weight: 46.5 pounds
- Dust often using a soft, dry cloth.
- Blot spills immediately with a clean, damp cloth.
- Avoid using harsh chemicals and abrasives as they may damage the finish.
- Shipping & Return Info
This is a general shipping item.
Shipping Information
Hassle Free Returns
To make this gift-giving season a little merrier, we are extending our Returns & Exchange Policy. For all items purchased between Oct. 21 and Dec. 24, 2016, you'll have until January 31, 2017 to return the item for a refund of the merchandise value. Just make sure to bring your proof of purchase or gift receipt. Quick Ship upholstery items are excluded from the Extended Holiday Return Policy. You have 7 days to return your Quick Ship upholstery item for a full refund or exchange.
The following items are non-eligible for returns or exchanges:
- Monogrammed items
- Mattresses
- Gift cards
- Made to Order items, including custom rugs and furniture
- Final Sale items (identified by a price ending in $.X7 or $.X9)
- Items damaged through normal wear and tear.
Delivery fees are non-refundable and prior purchases are not eligible for price adjustments.
For more information, view our full Returns & Exchange Policy.


text:
We're doing some work for www.thechapar.com - they're a great service, check them out if you're in the UK.
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Retail Businesses For Sale in Salem MA
Searched the MergerNetwork database for Retail Businesses For Sale in Salem MA and found the following matches.
Used Tire and Auto Repair Business #454472 posted Sep 22, 2016
- Salem, Massachusetts, United States
- $350,000
Well established new and used tire business located north of Boston. Fantastic cash flow and constant stream of customers from both the Boston area as well as New Hampshire. Business includes two auto repair stations and contract mechanics. Customer base includes fleet accounts, used car dealers...
Did you know that social networking is a great way to buy a business? Sign up now and we'll show you how.


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Hedge fund returns12 Sep 2010
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Research ranks Soros fund as 'absolute return' star
George Soros' Quantum hedge fund has generated the highest "absolute returns" for clients, compared to any of its nearly 7,000 industry peers, research by Rick Sopher, chairman of Leveraged Capital Holdings, has claimed.
Since its inception in 1973, Quantum has made its investors $32bn (€25.16bn), translating into an annual average of over $900m, the report said.
The study, which excluded low-return funds from its analysis, revealed that the top 10 most successful hedge funds have generated an aggregate $154bn since their establishment - with most of them typically dating back to the early 1990s or before. Brevan Howard is the only non-US fund to figure in the top 10 list.


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January 31, 2007
WARNER DOUGLAS WILLIAMS, PETITIONER,v.ALBERTO GONZALES, ET AL., RESPONDENTS.
Petitioner currently is incarcerated at a Federal Correctional Institution in Oakdale, Louisiana. Generally, he challenges the jurisdiction of the United States District Court for the Western District of Louisiana over his criminal case, and defense counsel's failure to raise this issue. Challenges to the jurisdiction of the federal court imposing sentence and attacks on the constitutionality of a federal prisoner's conviction both properly are raised in a motion to vacate, set aside or correct the sentence under Section 2255. See Taylor v. United States Bd. of Parole, 194 F.2d 882, 883 (D.C. Cir. 1952).
Section 2255 provides specifically that:
[a] prisoner in custody under sentence of a court established by Act of Congress claiming the right to be released upon the ground that the sentence was imposed in violation of the Constitution or laws of the United States, or that the court was without jurisdiction to impose such sentence, or that the sentence was in excess of the maximum authorized by law, or is otherwise subject to collateral attack, may move the court which imposed the sentence to vacate, set aside or correct the sentence.
28 U.S.C. § 2255 (emphasis added). Moreover, the ability to challenge a conviction by a motion to vacate sentence generally precludes a challenge by a petition for habeas corpus: [a]n application for a writ of habeas corpus in behalf of a prisoner who is authorized to apply for relief by motion pursuant to [28 U.S.C. § 2255], shall not be entertained if it appears that the applicant has failed to apply for relief, by motion, to the court which sentenced him, or that such court has denied him relief, unless it also appears that the remedy by motion is inadequate or ineffective to test the legality of his detention.
28 U.S.C. § 2255 (emphasis added).
The Court will dismiss the petition. An Order consistent with this Memorandum
Opinion is issued separately on this same date.
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The Day Alfred From Dark Knight Met Spiderman's Bernerd
One day Bruce Wayne had a party at his mansion. Lots of politicians, philantrophists as usual. But there was one person there who even Batman didn't know -- this old man who seems to be trying to standing up straight as well as he can from being so drunk.
So Bruce gets Alfred to interrogate him. He learns his name much faster then it rings a bell even though it should, for this is Bernerd from the Spider-Man movies. Norman and Harry Osborn's butler.
"I'm such an insignificant character," Bernerd whined. "Harry even makes his own omelets. What am, I doing is such a baller film series?"
"Oh come now, seh," Alfred replied. "You kept tight-lipped about the Goblin massacre occurring right under your nose. You are what James Bond would call a master criminal."
"Oh but it's more just that," Bernard says. "I don't even know how to keep frantic scientist assistants from bursting into Norman's study to tell him Doctor Strom is killed."
"Of course," Alfred says in return. "And who could forget the way you kept Wayne Manor from being paraded upon by...tonight's entertainment."
Bernard grins. "Hey yeah! You did kind of wussy out at that point."
"Yeah alright," Alfred says. "But did yo mama?"
And now for why Scottie Pippen was better than Michael Jordan. Click below!
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One of the great cinematic injustices was what occurred following the completion of the epic "Blood In Blood Out" (1993). I refer you to Sylvester Stallone and Al Pacino to illustrate my point, Sly...
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March 6, 2014 (Chinavestor) The overbought China stock monitor picked up a good number of important developments. First of all, E Commerce China Dangdang Inc. (NASDAQ:DANG) became extremely overbought after a 73% rally in the past 5 trading days! Perfect World Co. (NASDAQ:PWRD), Renren Inc. (NYSE:RENN), Sutor Technology (NASDAQ:SUTR) as well as Sohu.com Inc. (NASDAQ:SOHU) are stocks screaming on the overbought screen. SouFun Holdings (NYSE:SFUN) is also extremely overbought. And while the overbought chart is full of action, no oversold China stock exists at this moment.
Taking a closer look at the overbought China stock monitor, E Commerce China Dangdang Inc. (NASDAQ:DNAG) is far out there. The stock surged from the middle of its trading range to all the way to theoretical highs. Needless to say, the stock is extremely overbought. This implies DANG is expected to level off or fall slightly on Thursday and Friday before resuming a rally.
Perfect World (NASDAQ:PWRD) is another stock on fire. PWRD surged on Wednesday and is up 10% for the last three days as a result. Perfect World (NASDAQ:PWRD) leveled off on Thursday and may continue to advance on Friday or Monday.
Renren Inc. (NYSE:RENN) is up over 30% for the week and is overbought. Good news is that RENN surged the most on Wednesday with volume four times over average. This is very important because it shows strong money flows are present. This makes RENN less vulnerable to downside pressure.
Sohu.com Inc. (NASDAQ:SOHU), the most overbought China stock just earlier the week, has leveled off for the last three days. The stock is far from theoretical highs but is lacking momentum at this point. The overbought chart doesn't tell where SOHU is going to go from here. One thing looks certain: downside pressure is minimal right now.
SouFun Holdings (NYSE:SFUN) is another China stock on fire. The stock surged the most among major Chinese listings on Wednesday and is now extremely overbought.
This chart clearly shows Soufun Holdings (NYSE:SFUN) is now extremley overbought bacause it is now trading over two standard deviation above its trading range.
There are no oversold Chinese stocks at this moment. Chinese education stocks have leveled off just like China Telecom (NYSE:CHA) did. Mindray Medical (NYSE:MR) slid on Wednesday but is not considered oversold yet.
Overbought A technical condition that occurs when prices are considered too high and susceptible to a decline. Overbought conditions can be classified by analyzing the chart pattern or with indicators such as the one above. A sharp advance from $15 to $30 in 2 weeks might lead a technician to believe that a security is overbought. Or, a security is sometimes considered overbought when the stock is trading out of its trading envelope and is approaching the theoretical high. It is important to keep in mind that overbought is not necessarily the same as being bearish. It merely infers that the stock has risen too far too fast and might be due for a pullback.
Oversold A technical condition that occurs when prices are considered too low and ripe for a rally. Oversold conditions can be classified by analyzing the chart pattern or with indicators such as the one above. A sharp decline from $30 to $15 in 2 weeks might lead a technician to believe that a security is oversold. Or, a security is sometimes considered oversold when the stock is trading below its trading envelope and is approaching theoretical lows. It is important to keep in mind that oversold is not necessarily the same as being bullish. It merely infers that the security has fallen too far too fast and may be due for a reaction rally.


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Check in from 12:00 AM / Check out prior to 12:00 AM
Campanile Paris Ouest-Nanterre-La Defense: Find photos, reviews, information, amenities and compare prices for 2 stars hotels in Nanterre, France.
Campanile Paris Ouest-Nanterre-La Defense provides a comfortable setting while in Nanterre. It is conveniently located for guests wanting to sightsee in the area.
Hotel description
Campanile Paris Ouest - Nanterre - La Défense provides a 24/7 reception, plus a coffee bar and meeting rooms. For added convenience, it offers a wake-up service, a TV room and a lift.
Hotel Campanile Paris Ouest Nanterre La Defense provides modern rooms equipped with cable/satellite channels, tea and coffee making facilities and a flat-screen TV. Guests can unwind in the comfortable sitting area.
A satisfying breakfast is prepared every morning at Campanile, and there are numerous restaurants and cafés close by. Beverages are served at the bar.
The area surrounding Campanile Paris Ouest-Nanterre-La Defense is famous for its vibrant nightlife, with plenty of places to go for a drink or dance. The Arc De Triomphe and Champs-Elysees are within an easy drive from the hotel.
Hotel features
Restaurant, Air Conditioned, Cable / Satellite TV, Coffee / Tea Maker, TV, En suite, Private Bathroom
Elevator / Lift, 24 Hour Reception, Multilingual Staff, Wake-up Service, Meeting Rooms, Photocopier
Private Toilet
Availability and Prices
Booking Site
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Per room
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Per night
Users who viewed Campanile Paris Ouest-Nanterre-La Defense also viewed these 2 stars Nanterre hotels:
Sejours & Affaires Paris Nanterre Hotel
50 Rue De Vignes, Nanterre
50 Rue De Vignes, Nanterre
14 Avenue Pablo Picasso, Nanterre
14 Avenue Pablo Picasso, Nanterre
Ibis Nanterre La Defense
36/38 Avenue Champs Pierreux, Nanterre
36/38 Avenue Champs Pierreux, Nanterre
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841 reviews
Nearest hotels
- Ibis Nanterre La Defense
0.3 miles
- Hotel & Residence Mercure Paris La Defense Grande Arche
0.3 miles
- Hotel Itineraires
0.4 miles


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Check in from 2:00 PM / Check out prior to 11:00 AM
Isrotel Dead Sea Hotel and Spa: Find photos, reviews, information, amenities and compare prices for 5 stars hotels in Ein Bokek, Israel.
Providing views of Dead Sea, Isrotel Dead Sea Hotel and Spa is located near a popular shopping area, plus boasts a Jacuzzi. It provides 5-star accommodation and views of the sea.
Hotel description
There are a variety of amenities at Isrotel Dead Sea that guests can enjoy, including body treatments, a steam bath and a gym. There is an on-site day spa to enjoy, which features a beauty centre, as well as a range of body treatments.
Rooms at Isrotel Dead Sea Hotel are modern and have views of the sea and the mountains. Each provide tea and coffee making facilities, a refrigerator and a private bathroom with a hair dryer.
A satisfying breakfast is prepared each morning at Isrotel Dead Sea Hotel Ein Bokek, and there are numerous restaurants and cafés nearby. Room service is also available 24 hours a day.
The position of the hotel permits easy access to many tourist attractions by foot. Those wanting to discover the region can also visit Arad, located an easy car ride from the property.
Hotel features
Room Service, Restaurant, Air Conditioned, Refrigerator, Cable / Satellite TV, Coffee / Tea Maker, Hair Dryer, TV, En suite, Private Bathroom
Concierge, Elevator / Lift, 24 Hour Reception, Dry Cleaning, Babysitting / Child Services, Multilingual Staff, Safe-Deposit Box, Wake-up Service, Laundry service, Luggage Storage, Designated Smoking Area, Self Laundry
Fitness Room/Gym, Tour Desk, Massage / Beauty Centre, Bath / Hot Tub, Jacuzzi, Massage, Spa & Wellness Centre, Steam Bath
Body Treatments, Facial Treatments, Private Toilet, Kids Club, Executive Floor
Availability and Prices
Booking Site
Room Type
Per room
Per night
Per night
Users who viewed Isrotel Dead Sea Hotel and Spa also viewed these 5 stars Ein Bokek hotels:
Royal Rimonim Dead Sea
Ein Bokek, Dead Sea, Ein Bokek
Ein Bokek, Dead Sea, Ein Bokek
Daniel Dead Sea Hotel
Ein Bokek, Dead Sea Mobile Post, Ein Bokek
Ein Bokek, Dead Sea Mobile Post, Ein Bokek
Crowne Plaza Hotels Dead Sea
Ein Bokek M.P.O, Ein Bokek
Ein Bokek M.P.O, Ein Bokek
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563 reviews
Nearest hotels
- Daniel Dead Sea Hotel
0.1 miles
- Spa Club Hotel
0.2 miles
- Oasis Dead Sea
0.2 miles


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A couple of the highlights were CrossVegas, the Sram swag giveaway (they were giving away whole groupos), getting a pair of Q Rings, and a chat with Greg LeMond. I had a great time hanging out with Jim, Wick, and Henry for all those.
--Vino is going to do one more season! Looks like he's healed well and ready for another year of bike racing. For those of you who haven't liked him on Facebook (or me), I highly recommend it. Otherwise you'll miss out on regular updates like this:
--Looks like Gesink is out of Worlds with a broken femur. Meanwhile, Cav and Boom look to be on form for Worlds.
--Speaking of Cav, the other day at the Tour of Britain Eisel got off his bike on a climb to cheer Cav on! Hilarious!
--The recent Rasmussen case has gotten interesting. He looks to be innocent of doping but not of stupidity. Apparently, he's just really disorganized (according to a Tweet by Greg Henderson). Not to say that reporting your future whereabouts three months at a time is easy, but it's your job. Oh, and you can update via email or SMS. That being said, I consider myself pretty organized and if I were to, okay it wouldn't be that hard. The interesting part is that you can screw up two times within an 18 month period and not get busted. That's enough for two flights to St. Moritz.
Also, it looks like there might have been an error made by the authorities in the case so he may not get busted. However, the damage is already done because he's been fired by HTC and has lost the two year contract he had just signed with Garmin.
--WADA is considering a rule change for clenbuterol (and the steak). This could have some serious implications for Contador's case, not to mention the countless other non-superstar riders who are now out of work for two years.
--I'll leave you with this vid from the Tour of Britain. Check out the funny crash in the last turn (7:50)


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12920 Central Ave,Chino, CA 91710 | Map
Our goal is to provide complete, affordable dental solutions for each of our patients. We offer y... Read More
5370 Schaefer Ave,Chino, CA 91710 | Map
Tarsem L Singhal Dental Corporation based in the city of Chino in State of California is led by a... Read More
5250 Philadelphia St,Chino, CA 91710 | Map
Dr John Ramos & Staff welcomes you and your family to our office. Dr Ramos is a Member Of The Am... Read More
4648 Riverside Dr,Chino, CA 91710 | Map
Dr. Maria A. Cruz-Agustin General and Cosmetic Dentistry (Located in Ontario and Chino, Californi... Read More
13768 Roswell Ave.,Chino, CA 91710 | Map
14139 Pipeline Ave,Chino, CA 91710 | Map
13768 Roswell Ave,Chino, CA 91710 | Map
13788 Roswell Ave,Chino, CA 91710 | Map
8660 Central Ave,Montclair, CA 91763 | Map
On behalf of our entire dental team and myself, we welcome you to our dental offices. We hope you... Read More
212 W C St,Ontario, CA 91762 | Map
Our office offer friendly and dedicated dental services, taking as a first point the dental care ... Read More
276 W 9th St,Upland, CA 91786 | Map
Although Dr. Greenwood shares the name of George Washington's personal dentist,who made our first... Read More
1945 E Riverside Dr,Ontario, CA 91761 | Map
Olga Reyes, DDS - Ontario and Chino DentistDr. Reyes has been a dentist for years and has been th... Read More
150 W 1st St,Claremont, CA 91711 | Map
2409 S Vineyard Ave,Ontario, CA 91761 | Map
Both doctors Nguyens' are graduate of Loma Linda University School of Dentistry. Both have been ... Read More
1541 S. Garey Ave.,Pomona, CA 91766 | Map
Garey Dental le ofrece un servicio profesional en el cuidado dental en la ciudad de Pomona para t... Read More
5467 Moreno St,Montclair, CA 91763 | Map
Thank you for allowing us the opportunity to serve you. Our practice specializes in Family Denti... Read More
398 E Holt Blvd,Ontario, CA 91761 | Map
600 N Mountain Ave,Upland, CA 91786 | Map
Our office is dedicated to helping you achieve optimum dental health. We believe in comprehensive... Read More
1532 San Bernardino Ave,Pomona, CA 91767 | Map
528 N Fern Ave,Ontario, CA 91762 | Map
Ontario Family Dentistry in Ontario, CA serves customers.We offer services in Dentists.We special... Read More
101 W Mission Blvd,Pomona, CA 91766 | Map
At Soboh Dental Care, we are committed to providing you with the quality treatment you deserve. A... Read More
436 N Mountain Ave,Upland, CA 91786 | Map
Joseph Gray DDS, MS And Todd Ehrler, DDS, MS are Board Certified Orthodontists with more than 30 ... Read More
2217 S Mountain Ave,Ontario, CA 91762 | Map
600 N Mountain Ave Ste A205,Upland, CA 91786 | Map
Our office is dedicated to helping you achieve optimum dental health. We believe in comprehensive... Read More
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250 E 7th St,Upland, CA 91786 | Map
18 Rancho Camino Drive,Pomona, CA 91766 | Map
Koold Kidz Dentist Orthodontics es un consultorio dental pediatrico en el cual nos encargamos del... Read More
270 E 7th St,Upland, CA 91786 | Map
29. Lupita's Quality Dental - Nicolas Transito DDSwww.lupitaqualitydental.com
77 E 7th St,Upland, CA 91786 | Map
Lupita Quality Dental Nicholas Transito completed his education at the National Autonomous Univer... Read More
250 E 7th St,Upland, CA 91786 | Map
Shunk James G DMD in Upland, CA serves customers. Read More


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Bear Stearns fraud24 Dec 2007
Take a Financial News trial today:
- Breaking industry news & commentary
- 10 year searchable archive
- FN Powerlists & Special Reports
- FN on mobile and iPad
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Ex-Bear bankers plead guilty to fraud
Two former Bear Stearns investment bankers pleaded guilty to mail and wire fraud as part of a federal public-corruption probe in Texas that has implicated firms that underwrite municipal bonds.
Roberto Ruiz, former managing director at Bear Stearns' Dallas office, and Christopher Pak, former vice president in the office, admitted to conspiracy charges related to bribery schemes in El Paso.
The news comes as US federal officials pursue a yearlong nationwide criminal probe into alleged widespread bid-rigging in the municipal bond industry. Several Wall Street firms that underwrite the deals as well as insurers that handle part of the business have reported receiving subpoenas.


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Proxies for Privacy in Ambient Systems
The increased use of social-network services for sharing personal information has made it easier to gain awareness of each other. It has also increased the interest in privacy issues, especially since it is not always clear to the provider of information who gains access to personal data and to what end this data is being used. Many interesting ideas and proposals have appeared to address the issue of privacy vs. information sharing. One of the most interesting is perhaps the notion of minimizing asymmetry of information flow.
Provided by: Universitat zu Lubeck Topic: Security Date Added: Dec 2010 Format: PDF


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Stephanie Paolino is an associate and health care team leader at Vision 3 Architects, and recently was awarded the credential of Evidence Based Design Accreditation by the National Center for Health Design. In her position, she is involved in all phases of projects, from pre-design through construction administration. Her current projects include the Thundermist Health Center facility renovation in Woonsocket and University Medicine's new medical office building in East Providence. more
By Mary MacDonald
1 VoltServer Inc. received about $5 million in venture capital in 2015. How will you use this funding? Including the 2015 round, we have raised approximately $10.2 million in financing. The financing is primarily focused on scaling the … more
By Eli Sherman | firstname.lastname@example.com | 3/17/16
Tom Falcone was appointed interim executive director of Tech Collective, Rhode Island's information technology and bioscience association, on Feb. 1. Falcone talked with Providence Business News about the position. more
By Lori Stabile
Jennifer Zanni is the founder and president of the Endometriosis Foundation of Rhode Island, a 6-year-old nonprofit based in Lincoln. She has worked for CVS Health since 2006, most recently as a human resources senior consultant. Her personal struggles with the disease led to founding the nonprofit. Here she discusses its mission and outreach efforts. more
By Patricia Daddona
Richard Culatta is Rhode Island's chief innovation officer. His role will focus on opening up government and using data to solve problems. more
By Patricia Daddona | email@example.com | 3/23/16
Christopher Samih-Rotondo is the community organizer for the Tenant and Homeowner Association at DARE, or Direct Action for Rights and Equality, a Providence-based organization. He has held this position for five years. He is a graduate of Evergreen State College in Olympia, Wash., and an occasional contributor to local media, including the RI Future blog. more
By Mary MacDonald
Ron Simoneau is vice president of Shawmut Design and Construction in Providence, a national construction management company whose presence in Rhode Island has grown substantially over the past several years. He responded recently to questions posed by the Providence Business News. more
By Mary MacDonald
Heidi Farmer Piccerelli, a sales associate with Mott & Chace Sotheby's International Realty, recently completed the sale of a $2 million home in Warwick. This was the most significant sale in the city since September 2014. She responded this week to questions posed by the Providence Business News. more
By Mary MacDonald
Dr. Ghada Bourjeily is an attending physician in pulmonary services and obstetric medicine and director of research at the Women's Medicine Collaborative. She treats patients at Rhode Island Hospital and The Miriam Hospital. She is also an assistant professor of medicine at The Warren Alpert Medical School of Brown University. Her recent research has focused on sleep-disordered breathing and its impact on cardiovascular and metabolic outcomes during pregnancy. more
By Harold Ambler
Elizabeth Capalbo is founder and program director for the North Kingstown-based nonprofit Gaits of Harmony, which provides certified therapeutic riding programs. She founded the nonprofit in 2014 after acquiring two horses that were therapeutic equines and becoming certified as a registered instructor. Here she discusses the mission and value of the nonprofit. more
By Patricia Daddona


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Fresh Picked Concert Series
Downtown SLO Farmers' Market is proud to feature Fialta on Thursday, October 6th from 6:30 PM-8:30 PM at the Fresh Picked Concert Series, located in the Union Bank Parking lot at 955 Higuera Street. The Fresh Picked Concert Series is part of Downtown SLO Farmers' Market and is presented by The San Luis Obispo Collection, with support from Union Bank and Pacific Energy Company.
Fialta is local, indie-pop quartet that has come to describe their sound as "Central Coast Literary Pop", a genre they created for their sun-drenched, winter-dreading, narrative sensibilities. Their keyboard and percussion-driven music is inspired equally by a love of literature and the landscape of their beloved town, San Luis Obispo.
Thank you to our 2016 Sponsors:
Title SponsorThe San Luis Obispo Collection 999 Monterey Street San Luis Obispo, CA 93401 (805) 785-0511 www.SanLuisObispoCollection.com
Union Bank 995 Monterey Street San Luis Obispo, CA 93401 (805) 783-5140 www.UnionBank.com
Pacific Energy Company
2121 Santa Barbara Street San Luis Obispo, CA 93401 (805) 544-4700 www.AlterYourEnergy.com


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For Sale by Owner Isn't As Easy as it Looks
If you are interested in where the Bluffton / Hilton Head Island real estate market is going? Give Jo Anne or Tony Rizza (843-301-5825) a call to better understand the current market, see the latest available properties, or to list your own home!
With over 25 years of experience, our team is ready to help!
Hilton Head Real Estate Partners
Partnering with you every step of the way.


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Charming three bedroom vintage home nicely situated in a quiet location along The Delaware & Raritan Canal Towpath. This sweet property offers a detached garage/studio plumbed for radiant heat flooring. Enter through the tall wooden gate into the enclosed rear/side yard with a brick patio, very private, and plenty of garden opportunities. The garage/studio has the potential for an office, yoga studio, workshop, or garage. The main level has an open floor plan creating a contemporary feel for today's modern living. Beautiful hardwood flooring throughout add to the charm and character of the house. Plenty of built-in shelving and nooks are nice for displaying books and decorative items. A spacious living room is open to a large dining room, which also has an entrance to the front of the home with an open yard and a big shade tree, facing the tow-path. Dining room is open to the eat-in kitchen which creates a nice entertaining space. An extensive laundry/mud room, which has its own entrance to the rear yard is spacious enough and can easily be converted into an office space. A powder room completes the first floor. The second level has three bedrooms and a full bath with pine flooring and plenty of windows. In town living at its best!
Listing Area: Stockton Boro
The data relating to real estate for sale on this website appears in part through the TREND Internet Data Exchange program, a voluntary cooperative exchange of property listing data between licensed real estate brokerage firms in which Callaway Henderson Sotheby's International Realty participates, and is provided by TREND through a licensing agreement and identified with the TREND IDX Logo. Some properties which appear for sale on this website may no longer be available because they are under contract, have sold or are no longer being offered for sale. Some real estate firms do not participate in IDX and their listings do not appear on this website.Some properties listed with participating firms do not appear on this website at the request of the seller.
2016 TREND, All Rights Reserved. Information Deemed Reliable But Not Guaranteed.


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Face2Face is a multiplayer game where players can duel with other players or play vs the computer using the mouse to draw bullets and barriers... wins who hits and doesn't let hit
Either scripts and active content are not permitted to run or Adobe Flash Player version
13.0.0 or greater is not installed.
use WASD keys to move and jump
use the mouse to draw bullets and barriers:
- draw a circle with the mouse holding left button pressed to make a bullet, then click and drag themouse to choose force and direction
- draw a vertical or horizontal line to make a barrier
Is this game not working? Any suggestions? Send your comments.


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Swiss exchange gets tough on governance
The SIX Swiss stock exchange is investigating a listed asset manager over possible breaches of its corporate governance provisions, regarding disclosure of the company directors' roles in its 2008 annual report.
Vontobel Holding has been singled out as having potentially failed to adequately disclose and explain in the report how its executive structure worked.
The exchange, which is part of the SIX group, implemented an updated standard of corporate governance disclosure for the 2007/8 annual reporting season in September 2007.
The standard called for full clarification of the role of each executive committee member, working methods and compensation structures in order to improve transparency for investors. This move comes as Sir David Walker has today outlined plans to improve corporate governance among banks and financial institutions in the UK.
A spokesman for Vontobel told Financial News that the company was not permitted to comment on the investigation, but said it believed that it had fully complied with corporate governance standards and its annual report was in line with those of its peers.
A spokesman for the exchange said the investigation could take up to six months to complete.
Vontobel runs funds out of Switzerland and the US; in July the holding company announced it would buy the Swiss arm of Commerzbank.
– Write to: firstname.lastname@example.com
– Vontobel's 2008 annual report can be seen here: http://bit.ly/4o8x1U


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BCX Holiday Party for Business Owners
Business Connection Exchange - BCX
Monday, 12 December 2016 from 6:00 PM to 9:00 PM (EST)
Who's Going
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3 of your friends are going. Share it to get more people on board! Share
Sara Haughty
San Francisco, California
San Francisco, California
Luke Picard
London, United Kingdom
London, United Kingdom
Rick Vespucio
Florence, Italy
Florence, Italy
Event Details
Join Business Connection Exchange members for our annual holiday party. Members, guests and future members are welcome to attend this event. As a business owner you are invited to bring your spouse, your staff or your clients. Hot and cold appetizers will be served along with a cash bar. Door prizes will be part of our evening.
Have questions about BCX Holiday Party for Business Owners? Contact Business Connection Exchange - BCX
Save This Event
Event Saved
When & Where
Hot House Cafe
35 Church St,
Monday, 12 December 2016 from 6:00 PM to 9:00 PM (EST)
Add to my calendar
Business Connection Exchange - BCX
Business Connection Exchange is a business networking group that has chapters hosting regular meetings and special events to help businesses connect to the people and resources they need to grow their business. This group was set up by the members for the members.
BCX Holiday Party for Business Owners
Things to do in Toronto


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Horizon is an exclusive complex nestled in the Amapas hills with commanding panoramic views of the Banderas Bay and exclusive amenities such as security, 3 common pools (2 heated in the winter months), parking, gardens, and elevator service to all floors.
This corner unit is furnished with casual Asian elegance that complements the minimalistic modern design beautifully. As you come into the unit you will be surprised by its spacious and bright living areas all incorporated for entertainment. Provided with floor-to-ceiling sliding glass doors and windows, the inside flows onto the outside terrace.
The guest suite has direct access to a full bathroom and enjoys views of the hillside and jungle, the master bedroom has an oversized walk-in closet and en-suite bathroom with a Jacuzzi
Last Updated: Monday, 10 October 2016
All information is deemed reliable but not guaranteed. The listings on this site are displayed courtesy of the IDX program of AMPI Vallarta Nayarit MLS and may not be the listings of the site owner.


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