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Not Cool Cupid – Romantic comedy
alternate title — Uncool Cupid
Screenplay by Alan Nafzger (126 pages)
LOG-LINE – When an internet dating site performs a social science experiment, purposely mismatching couples, eight internet daters find that opposites attract.
Eight internet daters find that opposites attract when an internet dating site performs a social science experiment, purposely mismatching people.
A dating website is used as a social science laboratory and the sites users are not told.
The research finds that if a user was told that another user had a high compatibility score instead of a low one, the user was slightly more likely to reach out with a message. Those who believed they were corresponding with a good match were almost twice as likely to send at least four messages compared with people who were told they were a low match.
But what happens to the people involved when they find out their true compatibility?
The effect on the eight people searching for love is profound and certainly creates three dramas. In the subplot, the site hid profile text to see how it affected personality ratings.
All three couples make it though the social experimentation. The reason is that they want to. They may have entered into the online dating scheme thinking they want similar. They search for similar (compatible) mates, but once they are into the relationship they learn opposites attract. They stick together even after the experiment becomes public.
When the website tells users who were poorly matched that in fact they were great matches…
- One couple becomes happily married and then and momentarily questions their entire marriage when the results are announced. They have relocated and changed jobs to be together.
- A second couple have moved into the same apartment together, when they receive the news that they might not be as compatible as they thought.
- A third couple are seriously dating when they learn they have been the social scientists guinea pigs.
The service also told good matches that they were terrible for each other.
- There is also a fourth (star matched) couple that are attracted by each other's photos; they exchange a single message but erroneously thinking they aren't compatible don't follow through. They are each haunted by this. They have read each other's profiles and they feel it might be a match, but they look at the websites compatibility rating. They become disillusioned with online dating and delete their profiles. As the movie plays out, the audience should wonder if perhaps the website hasn't ruined their happiness. They by chance meet each other off the internet
The moral of the story is… it isn't up to any website to match people. Websites might influence people; however the real choice to work though any compatibility issues belongs wholly to the participants.
- Not Cool Cupid Screenplay
- Not Cool Cupid Screenplay
- Not Cool Cupid Screenplay
- Not Cool Cupid Screenplay
- Not Cool Cupid Screenplay
The idea and inspiration for this screenplay is based on facebook.com's admitted social experimentation. The date of copyright is June 30th, 2014.
- http://www.forbes.com/sites/jeffbercovici/2014/06/30/facebooks-experiment-on-emotions-sounds-creepier-than-it-was/
- http://www.huffingtonpost.com/daniel-j-solove/facebook-psych-experiment_b_5545372.html
- http://en.wikipedia.org/wiki/Cupid
- http://www.britannica.com/EBchecked/topic/146701/Cupid
- http://www.pantheon.org/articles/c/cupid.html
Republished by Blog Post Promoter


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Aug 09, 2016
CAIRO [MENL] -- Iran was said to be selling weapons to Islamic rebels inEgypt.
Jul 19, 2016
WASHINGTON [MENL] -- President Recep Erdogan could have staged a militarycoup to consolidate his dictatorship in Turkey.
Jul 08, 2016
ANKARA [MENL] -- Turkey plans to integrate anti-tank guided missiles oncombat platforms.
Jul 05, 2016
ABU DHABI [MENL] -- Kuwait has reported foiling mass-casualty plots byIslamic State of Iraq and Levant.

subset: commoncrawl


text:
John Mayer has dropped out of a tribute concert honoring Prince tomorrow night.
Mayer had a "change of schedule'' and has had to withdraw from the concert at Xcel Energy Center in St. Paul.
Performers still in the lineup include Stevie Wonder, Christina Aguilera, Chaka Khan and Prince's ex–wife Mayte Garcia has just signed up.
Members of the New Power Generation and 3rdEyeGirl will act as the house band.


text:
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Customer Reviews
If you like anime... you NEED this app
Cheap price and high quality.. This app is really great.. I can honestly say I have no complaints. I ALWAYS stream to my chromecast. If you get this app, I would definitely recommend getting the premium membership!! You'll save so much time by not watching ads, and your money will support the anime industry!! Their free trials are very generous, and you can cancel before your trial ends to not pay.. unlike a lot of free trials where they charge you for the next month in advance.
... but as a warning...you'll definitely want to stay subscribed after your trial.
Another GREAT thing. They are a partner to Loot Anime (the monthly anime box) .. and if you stay subscribed to crunchyroll, you get like $5 off your Loot Anime boxes each month! So if you are doing Loot Anime anyway, I don't see why you wouldn't want to just get this along with it :p
It's an app that I definitely use daily by all means. The anime they have is quite expansive and is growing by the season. Though they--unfortunately--don't have ALL the anime, they still have quite a good bit, which is wonderful.
They also included a night mode which is handy for the eyes (though I just use it regardless of the time of day).
If there is anything that I'd complain, it's that everything you bookmark is in a single tab, if you're watching them or not, seasonal or not; everything you bookmark is in one big list. It'd be nice to be able to bookmark different series so you can differentiate series you're currently watching from the ones you will watch in the future or even the anime that's airing seasonally. It's just a little quirk that doesn't ruin the experience too bad at all. The app as it stands is completely fine
--great even. There's just a few things I'd personally like that would make my experience better.
The best way to stream anime
Crunchyroll has a great app and overall it is the best way to stream anime on the go. The best part of using crunchyroll is that all of the anime is legally purchased by Crunchyroll so you know that when you watch through this app you are supporting the actual content creators. That being said you're able to watch anime for free as long as you're fine with a few commercials. You can get a premium account for a low price and that will allow you to watch all of your anime commercial free.
- Free
- Category: Entertainment
- Updated: Oct 20, 2016
- Version: 3.0.2
- Size: 74.1 MB
- Languages: English, Catalan, Czech, Danish, Dutch, Finnish, French, German, Greek, Hebrew, Hungarian, Indonesian, Italian, Japanese, Korean, Norwegian Bokmål, Polish, Portuguese, Romanian, Russian, Simplified Chinese, Slovak, Spanish, Swedish, Traditional Chinese, Turkish
- Seller: Ellation, Inc.
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Compatibility: Requires iOS 8.0 or later. Compatible with iPhone, iPad, and iPod touch.Apple TV: Yes
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- Monthly Premium Membership$6.99
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Select Date
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Tranquility of West Bali National Park offers a fitting place for a memorable vacation. It is the largest resort with 382 hectares within the boundaries of the Bali Barat National Park and offers guests the chance to get close to nature and relax in exquisite surroundings. You can do various activities here. One of them is adventure biking.
"Nice Place to go for an afternoon"
I love to bring family and friends there when they come as it is quiet and surrounding by forest. The food is bit expensive but you dont have to drink or eat. The view is fantastic especially early...
Visited Oct 2016 Read More...
"Beautiful, serene place, not like anywhere else in Bali"
My husband and I spent a week at the Menjangan for our honeymoon. it was the perfect, romantic place to relax and enjoy beautiful natural surroundings. Away from the usual hustle and bustle of Bali...
"Isolated resort within a National Park"
Stayed 4 nights at the end of our two weeks in Bali. This resort was probably the highlight as it's so unique. It is a long drive from the South of the Island but well worth it. Each part of the...
Visited Sep 2016 Read More...
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The BIGGEST LIES have been taught to HIDE the GREATEST TRUTHS! EVERY LIE a man believes is an OBSTACLE against his PER-ceiving the GREATEST TRUTHS! PRE-CONDITIONED and MISoriented after WORLDLY STATUS QUOS, many draw HASTILY UNJUST CONCLUSIONS leaving them BONDAGE to MISruling entities. Thriving upon "flattery of opinions" trusting in the KINGS, many never RECEIVE to the TRUTH! Their "GUT-REACTION" upon being introduced to UNcommon knowledge of the REALITY is to INSULT and MOCK! (Yacob/ James 1:1-9, ISAIAH 57, 28:10-23, 65:12, Zeph.3:1-5) WHO but the MOST HUMBLY DILIGENT and FAITHFUL SOUL upon hearing the CALL of the MOST HIGH, will trust fervently to hearken diligently to overcome every PARTIALITY to OVERCOME the WORLD?
Isa 57:11 And of whom have you been in dread and fear, that you have lied against Me and have not remembered Me nor laid Me to your heart? Behold, I am the Holy One of old, and you did not revere Me.
Isa 50:2 WHY, when I came, was there NO MAN? When I CALLED was there NONE TO ANSWER? Is My hand SHORTENED at all, that it canNOT SAVE? Or have I no power to DELIVER? Behold, at MY REBUKE I DRY UP THE SEAS, I make the RIVERS a DESERT; their fish stink because there is no water. They die of thirst. (Isaiah 19:1-5 & 18-25) 50:3 I clothe RULERS ON HIGH with DARKNESS and make sackcloth/ SHAME their covering. 50:4 The MOST HIGH YAH has given Me the TONGUE of the LEARNED, that I should KNOW HOW TO SPEAK and DECLARE A WORD to the WEARIED! HE wakens ME in the morning; in the morning HE causes MY ears to HEAR the TEACHING. 50:5 As the MOST HIGH YAH OPENED MY EARS, I TURNED NOT BACK THE EVIL WAY, NEITHER was I REBELLIOUS!
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Here a Video Review Of Zev0's and Raiya's versatile Growing Up Skin Merchant Resource Bundle for Genesis 3 that was in the Newly Mad Category on Day 1 of this years March Madness Sale at DAZ3D
March Madness Reviews: Day1 – Bed Hogs
Here a Video Review Of Devon's creative Bed Hogs that was in the Newly Mad Category on Day 1 of this years March Madness Sale at DAZ3D
You can also have a look at Bed Hogs's 3D-Alamanc Page
March Madness Reviews: Day 1 : Chez Lucille Hair Salon
Here a Video Review Of SloshWerks lovley Chez Lucille Hair Salon that was the Daily Mind Blower on Day 1 of this years March Madness Sale at DAZ3D
You can also have a look at Chez Lucilles's 3D-Alamanc Page
DAZ3D March Madness Sale Introduction
Have Fun with our short March Madness Sale Buyers Guide.
A Quick Introduction how the Sale works, and the some thoughts about what we belive is a good buying strategy.
Tutorial: Metadata 101 – Create Smart Content Metadata for 3rd Party Content in DAZ Studio
Today we have a video tutorial for you.
In it we show you how you create metadata for 3rd party content so you can use it in the smart content Pane of DAZ Studio
Review: DAZ-23821 DA Real World Lighting
Have fun with this Review of the Product "DA Real World Lighting" from DAZ, a collection of light/render presets for Iray Sun Sky Mode.
You find the Product at:
The Product page in our Wiki is going to be added in the next days
We have Started
Dear Visitor,
we have just started with 3D-Almanac. We aim to be the one-stop-site that you need to find the right content for your render project, no matter where it was published.
But as I write this, the site is still pretty empty and we are entering a very early beta phase. So please be invited to follow us on this journey and come back often.
During the next weeks and months we are going to add new content to the page probably daily but at least multiple times a week.
We also plan to add video reviews of interesting content as well as well as free video tutorials.
So thanks for visiting us and I hope to see you again soon!


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Reviewed Work: The Political History of England. by Hunt, Poole, George Burton Adams
Review by: Charles A. Beard
Political Science Quarterly
Vol. 21, No. 3 (Sep., 1906), pp. 531-535
Published by: The Academy of Political Science
Stable URL: http://www.jstor.org/stable/2140602
Page Count: 5
Subjects: Political Science
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Political Science Quarterly


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Flamingo Decor
Flamingo Watercolor Painting, Set of 2 Birds, Pink Abstract Art Print, Flamingos…
flamingo, love this How stunning is this. DS Interiors
Flamingo Rustic Shabby Chic Wooden Wall Decor by ThePinkToolBox
Flamingo Print Be Yourself flamingo prints by WeArePaperPlane
Hey, I found this really awesome Etsy listing at https://www.etsy.com/listing/209199731/flamingo-sign-flamingo-decor-be-a
Flamingo Mason Jars - flamingo party favors - hawaiian party decor - luau party centerpieces
Elizabeth Burns Design | Beach Room Design - Navy and Pink Bedroom with Flamingo Decor
Make your own luau, pineapple party or flamingo party decorations with easy tissue pouf pineapple and flamingo tutorials.
Adairs Flamingo Cushion


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Earle's Paint Place
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5 Hospital RdMap
Emerald QLD 4720Click to view map
About Us
Whatever you are looking for, whether acryllic paint, painters or paint guns, if it is a Paint & Painting Equipment product or service then Earle's Paint Place are the people to speak to. We service a wide area from our main premises at Emerald, QLD. Email us or call on (07) 4982 #### to find out more about our Paint & Painting Equipment range of products and services.
View similar businesses near: Emerald QLD
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Professional Painter Melbourne Metro
"Artisan painting services provided us with exceptional service, quality paint work and were very efficient. They offer the best painting services Melbourne. We are gladly happy to recommend there services for painting. Paul and Julie, Epping"
Professional Painter Melbourne Metro
"I dealt with these guys some time ago and I found them professional very good communication skills and finished my project on time. I highly recommend them to everybody.
Gold Coast"
Julie and Paul on 27th Sep 2011
Sash on 25th Jul 2011


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Super Thick Potholder
Designed by Julie A. Bolduc
Date Added: October 1, 2004
This potholder uses the new stitch Single Crochet front back bobble. It produces a very thick potholder that is fast to make.
Thank you for using this download page to download this PDF file. Please link to this page from your web site if you want to link directly to the pattern. Do not link directly to the PDF file or I will have to start changing file names of the PDF files in the future. Thank you.


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When making peanut butter cookies, don't use the fork to make the criss cross design on top. Instead, get out your potato masher, dip in a little sugar or water (to avoid sticking) and press the tops of the dough. You have instant criss crosses.
This is a great tip, very simply and fast. Thanks for sharing Sandi!!
I like that tip too!
Add your voice! Click below to comment. ThriftyFun is powered by your wisdom!


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|This is a discussion on $200 NLHE Full Ring: Live hand: Bottom set, multi way, how to maximize? within the online poker forums, in the Cash Game Hand Analysis section; Live table 1/2 NL Playing for about 3 hours My image has been pretty tight, haven't shown down any hands, table saw me call villan's all in
$200 NL HE Full Ring: Live hand: Bottom set, multi way, how to maximize?
Live table 1/2 NL
Playing for about 3 hours
My image has been pretty tight, haven't shown down any hands, table saw me call villan's all in on river w/ 99 on A734Tr board
Villan UTG $500
Villan MP $90
Villan CO $300
My analysis of villans:
UTG - playing very snug, won a couple hands and has been sitting back, pretty tight/ABC
MP - spewy, saw him 3 bet shove QTs on AQ4r board
CO - Station, sees a lot of flops, haven't seen anything amazing about his play yet.
Villan UTG raises $15
Villan MP calls $15
Villan CO calls $15
HERO SB 9c9h calls $15
Flop: Kd Jd 9s
HERO checks, Villan UTG bets $40, Villan MP shoves all in $90, 1 fold
Anyone like flatting here? Or just 3-bet shove over the MP all-in and hope I don't get snapped by KK/JJ???
The hands I've given MP to shove would be any KQ/KT, 2-pair combination, any Axs-9xs and of course QT. I don't think he would have a higher set here, ever.
Villan UTG's range is a bit tighter probably looks more like TT+/ATs+/AJo+
I feel that the only hands that would call my all in shove would be KK/JJ/AQs-ATs every other hand folds. Ideally he'll over-call with AA/AK, but I don't see that happening. I don't see him c-betting QQ/TT here. So really his range is more like ....AA/KK/AK/JJ/AQs-ATs.
How do you guys feel about this? Plan for rest of hand also?
I'd just shove over the top.
Yea QQ and TT likely arent cbetting this flop into this many opponents so straights may not worry you that much, but villain could have AQ/AT of diamonds, in addition if villain does have a AA/AK type hand straight completing turns can kill your action and force both of you to slow down. Shove and get called by big draws, AA AK KJ (in addition to coolers KK and JJ obv). If you think villain will chuck AA and AK to shoves, flatting is ok hoping he'll call behind you and then maybe even lead a blank turn putting you on a draw at which point you shove. You also shove if checked to on blank turns to potnetially fold out big draws like AQdd ATdd
I'm often leading wet boards with monsters. We trap KQ/AK/AA/KJ/FDs/pair+gutshot hands etc into flatting whereas they might not cbet when checked to, and we prevent them from seeing a scare card or a card that improves their hand.
I think c/r is fine too as you have perfect relative position to the PFR (ie you check, PFR bets, often others just flat behind, trapping dead money in the middle, and we raise). If the PFR was to your right I'd say it was a mandatory lead.
As played I probably just jam too. Flush draws, top pairs and overpairs don't fold in live poker, plus our shove looks like a draw trying to get the most fold equity as possible, so we could get looked up lighter than if we c/r small and potentially scare away KT or something.
I agree with the shove on the flop. If you run into a straight you've still got outs.
I'd peg one player for a pair and a gutshot and the other for a FD.
Even against a flopped straight you're still ~14-15% to improve on the turn and ~20-21% to improve on the river.
As weird as it sounds, I fold here. This is a beyond draw heavy board, strong UTG has shown strength both pre and on flop out of position, and then spewy pushes. Could easily have Q10, big diamond draw, set over set. If you truly want to get in with it though, you have to push. Like I said, too many draws to contend with
UTG might have set over set, but the short stack surely pushes pre with an overpair.
re: Poker & $200 NLHE Full Ring: Live hand: Bottom set, multi way, how to maximize?
If the read is right and he is a strong player he wont be raising utg with Q10, probably no KJ either. if it is JJ or KK then i take the pproach usually that if you get done set over set then its not meant to be your day.
Ok well,
villan would almost never have QT in this spot like I said, his been playing snug, only playing good starting hands.
There is a chance the small stack could have QT, but at this point i'm almost never folding my hand, and if villan has KK/JJ its a cooler, life goes on.
I thought about this a lot, and I figured against another player, or if I was a little more shallow with my stack I would have just shoved.
I ended up flatting. Villan also flatted behind me.
Turn 2c
I led for all-in. Villan folds AKo face up.
River 4c
All shows Ad9d pair of 9s
Hero shows 9 9 set of 9s


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Israel Inspired: What's the Story with these Torah Observant Gentiles? [audio]Sunday, September 4th, 2016
As Jeremy returns from his cross country tour, he and Ari discuss the historically unparalleled phenomenon of Torah studying gentiles who love Israel and the Jewish people. What is at the core of this movement? What is the motivation? Tune in as Ari and Jeremy address both the harmony and the tension that this revolution is bringing to the world.The Land of Israel


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September 6, 2011
PERRY TALLEY, CDCR #D-91162, PLAINTIFF,v.GEORGE NEOTTI; S. PAULEY; RATHERFUR; J. WALKER; SPENCER;JOHN DOE NURSE; JOHN DOE PHYSICIAN DEFENDANTS.
ORDER DIRECTING U.S. MARSHAL TO EFFECT SERVICE COMPLAINT PURSUANT OF SECOND AMENDED TO FED.R.CIV.P. 4(c)(3) & 28 U.S.C. § 1915(d)
On February 23, 2010, Plaintiff, Perry Talley, a state prisoner currently incarcerated at Kern Valley State Prison located in Delano, California and proceeding pro se, filed a civil rights action pursuant to 42 U.S.C. § 1983. Plaintiff alleged that his Eighth Amendment rights were violated when he was housed at the Richard J. Donovan Correctional Facility ("Donovan"). Plaintiff also filed a Motion to Proceed In Forma Pauperis ("IFP") pursuant to 28 U.S.C. § 1915(a). The Court has granted Plaintiff's Motion to Proceed IFP but has also sua sponte dismissed his original and First Amended Complaint for failing to state a claim. See May 3, 2010 Order; see also August 3, 2010 Order.
On June 27, 2011, after receiving an extension of time. Plaintiff has now filed his Second Amended Complaint.
SUA SPONTE SCREENING PER 28 U.S.C. § 1915(e)(2) AND § 1915A
A. Standard
The PLRA also obligates the Court to review complaints filed by all persons proceeding IFP and by those, like Plaintiff, who are "incarcerated or detained in any facility [and] accused of, sentenced for, or adjudicated delinquent for, violations of criminal law or the terms or conditions of parole, probation, pretrial release, or diversionary program," "as soon as practicable after docketing." See 28 U.S.C. §§ 1915(e)(2) and 1915A(b). Under these provisions, the Court must sua sponte dismiss any IFP or prisoner complaint, or any portion thereof, which is frivolous, malicious, fails to state a claim, or which seeks damages from defendants who are immune. See 28 U.S.C. § 1915(e)(2)(B) and § 1915A; Lopez v. Smith, 203 F.3d 1122, 1126-27 (9th Cir. 2000) (en banc) (§ 1915(e)(2)); Resnick v. Hayes, 213 F.3d 443, 446 (9th Cir. 2000) (§ 1915A).
The Court finds that Plaintiff's claims are now sufficiently pleaded to survive the sua sponte screening required by 28 U.S.C. §§ 1915(e)(2) and 1915A(b). Therefore, Plaintiff is entitled to U.S. Marshal service on his behalf. See Lopez, 203 F.3d at 1126-27; 28 U.S.C. § 1915(d); FED.R.CIV.P. 4(c)(3). Plaintiff is cautioned, however, that "the sua sponte screening and dismissal procedure is cumulative of, and not a substitute for, any subsequent Rule 12(b)(6) motion that [a defendant] may choose to bring." Teahan v. Wilhelm, 481 F. Supp. 2d 1115, 1119 (S.D. Cal. 2007).
Good cause appearing therefor, IT IS HEREBY ORDERED that:
1. The Clerk shall issue a summons as to Plaintiff's Second Amended Complaint [ECF No.13] upon Defendants and shall forward it to Plaintiff along with a blank U.S. Marshal Form 285 for each of these Defendants. In addition, the Clerk shall provide Plaintiff with a certified copy of this Order, the Court's May 3, 2010 Order granting Plaintiff leave to proceed IFP [ECF No.4], and certified copies of his Second Amended Complaint and the summons for purposes of serving each Defendant. Upon receipt of this "IFP Package," Plaintiff is directed to complete the Form 285s as completely and accurately as possible, and to return them to the United States Marshal according to the instructions provided by the Clerk in the letter accompanying his IFP package. Thereafter, the U.S. Marshal shall serve a copy of the Second Amended Complaint and summons upon each Defendant as directed by Plaintiff on each Form 285. All costs of service shall be advanced by the United States. See 28 U.S.C. § 1915(d); FED.R.CIV.P. 4(c)(3).
2. Plaintiff shall serve upon Defendants or, if appearance has been entered by counsel, upon Defendants' counsel, a copy of every further pleading or other document submitted for consideration of the Court. Plaintiff shall include with the original paper to be filed with the Clerk of the Court a certificate stating the manner in which a true and correct copy of any document was served on Defendants, or counsel for Defendants, and the date of service. Any paper received by the Court which has not been filed with the Clerk or which fails to include a Certificate of Service will be disregarded.
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Download apps, toolboxes, and other File Exchange content using Add-On Explorer in MATLAB.
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News Articles
ESPN Taps Former Redskins, Giants Player as AnalystAntonio Pierce will appear on SportsCenter, NFL Live, more 7/08/2010 09:00:00 AM Eastern
has named Antonio Pierce to be an NFL analyst.
retired this year after nine seasons with the Redskins and later the Giants,
including the Super Bowl champion Giants team in 2007.
former linebacker will be featured on NFL Live, SportsCenter, ESPNEWS, as
well as on ESPN radio and online in New York.
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Ricoh SP 3600DN Black and White Printer / Mfr. No.: 407314
Meet your match: big printing for small offices
Even though the RICOH SP 3600DN is small enough to fit on a desktop, you don't have to compromise when it comes to managing and sharing information. Innovative LED print technology provides super high-quality printing at a very low price per page, and support for mobile printing simplifies collaboration.
General Features
Add a twist to mobile printing
Your office or department may be small, but you need to share information just as quickly as a big company. With the RICOH SP 3600DN, you can.
Print and share images, documents and photographs using the RICOH Smart Device Print&Scan app from your iPhone®, iPad® or Android™ smart phone or tablet — without print drivers.
Simplify how you work
Use the four-line LCD panel to check system status at a glance and speed through functions.
Raise the quality bar
Make every print job — even banners up to 35 inches long — look better by maintaining precise, sharp 1,200 dpi resolution, even when printing up to 31 ppm. The key is our LED print technology, which also keeps your cost per page very low.
Breeze through maintenance tasks
Access the photoconductor and toner from the front of the device. Use Web Image Monitor, Device Manager NX or @Remote to check settings, manage queues and complete maintenance tasks from your desktop.
Support your sustainability goals
With standard duplex printing, you'll use less paper. Double down again with the printer's EPEAT® Silver rating (EPEAT is a global environmental rating system for electronic products) and ENERGY STAR® certification.
Engine Specifications
Copier Features
Print Specifications
Other Print Features
Controller Options
Security Specifications


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The first full season for the Hammer City Roller Girls is coming to a close, with the "The Steel Town Showdown" set for August 25th.
This is not roller derby skating of the past – it's now a faced-paced and hard-hitting sport fueled by athletic endurance, strength, passion and entertainment. And this summer roller derby has become a "smash hit" as hundreds of fans from across the GTA have flocked to the Hammer to watch the roller girls battle it out on the track against their opponents.
Both Hamilton teams in the league have won challenges from teams in London, ON, Montreal, QC and Buffalo NY, USA. Now the Hamilton Harlots and The Steel Town Tank Girls will turn against each other to face-off in the 2007 season finale, "The Steel Town Showdown". It will take place on Saturday, August 25th at the Market Street Arena (J.L. Grightmire) in Dundas. The doors will open at 5:30PM and the game whistle will sound at 7:00PM.
The finale is an all-ages licensed event. Tickets can be bought in advance for $10 or $12 at the door. Children's tickets are $7. One dollar of each ticket sold will be given to the Hammer City Roller Girls charity of choice – The Soroptimist Club of Stoney Creek and Niagara. Also, in support of the Hamilton Food Bank the Roller Girls will be giving a free autographed game poster to each person who makes a non-perishable food donation.
Established in January, 2006, The Hammer City Roller Girls Inc. is an all female, skater operated roller derby league based in Hamilton, Ontario. Presently there are two teams within the league: The Hamilton Harlots and the Steel Town Tank Girls, amounting to approximately 30 skaters in total.
Within the first year, The Hammer City Roller Girls have grown in both athletic ability and popularity. The H.C.R.G. play on concrete or Sport Court floors and abide by the rules established by the Women's Flat Track Derby Association.
More information on the league and information on purchasing advance tickets can be found at http://www.hammercityrollergirls.ca/


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Wismec Reuleaux RX2/3 Box Mod
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07-18-2002, 01:28 PM #1Junior Guru Wannabe
- Join Date
- Oct 2001
- Location
- Philadelphia, Pa
- Posts
- 76
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Cowboy Birthday Party Supplies Canada
Wanted Poster Photo Prop is made of cardboard and measures approximately 37" wide x 25" high with a hole cutout for faces that measures approximately 6.25" wide x 6" high.
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Photo: Anson Smart
Recipe Time
Nutritional Information
Pat the chicken dry with paper towels and season with 1 teaspoon salt and 1/4 teaspoon pepper. In the bowl of a slow cooker, combine the chicken, onions, potatoes, squash, garlic, orange, broth, honey, and thyme. Set the slow cooker to high and cook, covered, until the vegetables are tender and the chicken is cooked through, about 2 1/2 to 3 hours. Divide the chicken mixture into individual bowls.
If You Don't Have a Slow Cooker: Heat oven to 325° F. Follow the recipe above using a Dutch oven or large casserole. Bake, covered, until the vegetables are tender and the chicken is cooked through, 2 1/2 to 3 hours.
This recipe was tested in a 6-quart slow cooker. Because different models cook at different rates, the cooking time below is presented as a range. Check for doneness at the low end of the range (but not before, as the escaped heat will significantly slow the cooking). If the food is not done, cover and cook to the end of the suggested time range. If using a slow-cooker smaller than 6 quarts, the cooking time may take an additional hour or more, and results may vary.


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In Stock
Expected to ship by .
$119.99Now: $59.99Save 50%
To view item in an alternate color, rollover swatch above.
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average rating: -- / 10
dopiero trzema dniami gościł Furtek Johnson w powiązaniu niepodzielnych wilków. Poprzez ostatnie trzy dzionków powiewy prysłyby tyle katarze z niezbadanego Barrenu, że ten iglak, pod как да �?големя пени�?а - �?големяване на пени�?
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I wanna cook
Cooking something?
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This mod has original and interesting ideas, along with some really cool vehicles. I wonder why it's totally canned.
in japan.
The player becomes a gentle Japanese and runs about Japan.
The Ground Self-Defense Force ? The Ground Self-Defense Force also mobilizes.
You should defend the public peace of Japan as a Japanese soldier.
MOD was made for Movies.
not completed Movie&MOD yet.
to be decided
Thanks for voting and helping Nieve2 on it's quest to become the 2016 Mod of the Year. You are now in with a chance to score some free games from our #modlove collection. Help this mod secure more votes by embedding the widget (or link) we have included below on your favorite sites.
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No articles were found matching the criteria specified. We suggest you try the article list with no filter applied, to browse all available. Post article and help us achieve our mission of showcasing the best content from all developers. Join now to share your own content, we welcome creators and consumers alike and look forward to your comments.
This mod has original and interesting ideas, along with some really cool vehicles. I wonder why it's totally canned.
Can we expect working AI?
And can you make a shopping mall map with indoor areas and AI-nodes in the indoor areas?
I wanna drive a tank into a mall, who else agrees?
Its 2011 and it said coming soon 2008... Dead Mod... mods dead.... no use in trying to get the beta here...
Please release the beta! It's looking awesome!
Lol looks funny your mod. ^^
Its a good new Mod i think, but i think its no more support it?
No Download exist?
This could be a new way of a Mod, but never released??:-(
looks good
I belive I saw a video of this on youtube but I dont speak Japanese so I couldnt find the right button to download it :D
Only registered members can share their thoughts. So come on! Join the community today (totally free - or sign in with your social account on the right) and join in the conversation.


text: Secondary School Geography 13 points Previous question Next question 3. Which of the above two resources can be transformed from a raw material into a finished product. Explain the process and depict it with the help of pictures. Cement, Coal, Iron-ore, Petroleum, food grains, Jute and Cotton 1 Ask for details Follow Report by srijangupta03 30.06.2014 Log in to add a comment


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400 Free Online Courses from Top Universities. Advertisement.
Top 10 Universities With Free Courses Online. #1 UC Berkeley Ranked as the #1 public school in the United States, Berkeley offers podcasts and webcasts of amazing professors lecturing.
Each course has an RSS feed so you can track each new lecture. For printable assignments and notes you can check the professors homepage, which is usually given in the first lecture or google his name. Even though the notes, homework and tests are not directly printed in the berkeley website, as they are in MIT and other courseware sites, it's not a problem to find them. I personally tried to use it for John Wawrzynek's machine structures class and the nutrition courses. Online Education Database - Online Colleges and Universities.
100 Incredible Lectures from the World's Top Scientists. Posted on Thursday June 18, 2009 by Staff Writers By Sarah Russel Unless you're enrolled at one of the best online colleges or are an elite member of the science and engineering inner circle, you're probably left out of most of the exciting research explored by the world's greatest scientists.
But thanks to the Internet and the generosity of many universities and online colleges, you've now got access to the cutting edge theories and projects that are changing the world in this list below. If you're looking for even more amazing lectures, check out our updated list for 2012 with more talks from great minds. General Let the world's top scientists explain exactly how they do their job when you listen to these lectures. Online Universities - Accredited Online University Guide. A complete list of free online courses offered by Stanford's Coursera, MIT and Harvard led edX (MITx+HardvardX+BerkeleyX), and Udacity. OER Commons. Steve Wheeler: Open Educations Wordwide! Chaîne de CollegeBinary. Keeping MOOCs Open. MOOCs — or Massive Open Online Courses — have been getting a lot of attention lately.
Just in the last year or so, there's been immense interest in the potential for large scale online learning, with significant investments being made in companies (Coursera, Udacity, Udemy), similar non-profit initiatives (edX) and learning management systems (Canvas, Blackboard). The renewed interest in MOOCs was ignited after last year's Introduction to Artificial Intelligence course offered via Stanford University, when over 160,000 people signed up to take the free online course. OpenLearn - The Open University. Massive open online course. Poster, entitled "MOOC, every letter is negotiable", exploring the meaning of the words "Massive Open Online Course" A massive open online course (MOOC /muːk/) is an online course aimed at unlimited participation and open access via the web.
In addition to traditional course materials such as filmed lectures, readings, and problem sets, many MOOCs provide interactive user forums to support community interactions among students, professors, and teaching assistants (TAs). MOOCs are a recent and widely researched development in distance education[1] which were first introduced in 2008 and emerged as a popular mode of learning in 2012.[2][3] A complete list of Massive Open Online Courses (free online courses) offered by the best universities and entities.
Microsoft PowerPoint - POEMs VUB14 - POEMs VUB14.pdf. Moosphere. Using mLearning and MOOCs to understand chaos, emergence, and complexity in education. Inge deWaard Athabasca University, Canada Sean Abajian Los Angeles Unified School District, USA Michael Sean Gallagher JSTOR, USA Rebecca Hogue University of Ottawa, Canada Nilgün Keskin Anadolu University, Turkey Apostolos Koutropoulos University of Massachusetts, USA Osvaldo C.
Abstract. Khan Academy. OpenCourseWare at the Johns Hopkins Bloomberg School of Public Health. Learn Science at Nature. Chaîne de khanacademy. Khan Academy is a nonprofit with a mission of providing a free, world-class education for anyone, anywhere.
We're entering a MacArthur Foundation competition, called 100&Change, for a $100 million grant to help solve a critical problem of our time. Millions of people lack the skills and credentials to participate in the global economy. To address this, our long-term goal is to develop internationally-recognized diplomas that provide direct access to economic and educational opportunities. We also plan to create free content and tools to help people earn the diplomas. If we win the grant, we'll be able to accelerate the development of the diplomas, content, and tools. Too many people lack the skills and credentials to participate meaningfully in the global economy.
Open Course Library. Smarthistory: a multimedia web-book about art and art history. Smarthistory offers more than 1500 videos and essays on art from around the world and across time. We are working with more than 200 art historians and some of the world's most important museums to make the best art history resource anywhere. Use the "subject" pulldown menu (go to "Arts and Humanities") at the top of this window or click on the headings below to access our content: Art history basics.
Educational Websites. Coursera. OpenStax College. TeacherTube - Teach the World. Oxford Open. OUP Supports Open Access Oxford University Press (OUP) is mission-driven to facilitate the widest possible dissemination of high-quality research.
We embrace both green and gold open access (OA) publishing to support this mission. A Proven Track Record of Success OUP has been publishing OA content since 2004. Since that time, 'gold' OA has grown dramatically and proven effective in some disciplines. Free Online Courses. Advance your College Education & Career. 8,200+ Strong, Researchers Band Together To Force Science Journals To Open Access. Evolutionary biologist Michael Eisen made this t-shirt design in support of the Elsevier boycott.
Academic research is behind bars and an online boycott by 8,209 researchers (and counting) is seeking to set it free…well, more free than it has been. The boycott targets Elsevier, the publisher of popular journals like Cell and The Lancet, for its aggressive business practices, but opposition was electrified by Elsevier's backing of a Congressional bill titled the Research Works Act (RWA). Though lesser known than the other high-profile, privacy-related bills SOPA and PIPA, the act was slated to reverse the Open Access Policy enacted by the National Institutes of Health (NIH) in 2008 that granted the public free access to any article derived from NIH-funded research. But the fight for open access is just getting started. Seem dramatic? Paying a high price for academic journals isn't anything new, but the events that unfolded surrounding the RWA was the straw that broke the camel's back.
Free Online Course Materials. FreeLearning.pdf (application/pdf Object) Commons learning alliance. InTech - Open Science Open Minds. Mary & mac design. Intro to AI - Introduction to Artificial Intelligence - Oct-Dec 2011. Learning for everyone, by everyone, about almost anything. Your Free Online School: Courses, Video Lectures, Documentaries, Images, Books and more. Alsica.pdf - isociety11.pdf. Learning Materials. DNA from the Beginning DNA from the Beginning is an animated tutorial on DNA, genes and heredity.
The science behind each concept is explained using... see more DNA from the Beginning is an animated tutorial on DNA, genes and heredity. Microsoft Word - 211-The MOOC as Distributed Intelligence- Dimensions of a Framework & Evaluation of MOOCs.doc - Framework-for-Design-Evaluation-of-MOOCs-Grover-Franz-Schneider-Pea_final.pdf.
12 Dozen Places To Educate Yourself Online For Free. All education is self-education. Period. It doesn't matter if you're sitting in a college classroom or a coffee shop. We don't learn anything we don't want to learn. Those people who take the time and initiative to pursue knowledge on their own are the only ones who earn a real education in this world.
Take a look at any widely acclaimed scholar, entrepreneur or historical figure you can think of. If you're interested in learning something new, this article is for you. Note that some of the sources overlap between various subjects of education. Online Courses - Anytime, Anywhere. OCW Consortium. OpenCourseWare. History[edit] The OpenCourseWare movement started in 1999 when the University of Tübingen in Germany published videos of lectures online for its timms initiative (Tübinger Internet Multimedia Server).[1] The OCW movement only took off, however, with the launch of MIT OpenCourseWare at the Massachusetts Institute of Technology (MIT) and the Open Learning Initiative at Carnegie Mellon University[2] in October 2002.
The movement was soon reinforced by the launch of similar projects at Yale, the University of Michigan, and the University of California Berkeley. MIT's reasoning behind OCW was to "enhance human learning worldwide by the availability of a web of knowledge".[3] MIT also stated that it would allow students (including, but not limited to its own) to become better prepared for classes so that they may be more engaged during a class. Serendipity. OpenCourseWare. Un article de Wikipédia, l'encyclopédie libre.
OpenCourseWare (OCW) désigne un projet destiné à mettre gratuitement en ligne des cours de niveau universitaire, de la même façon que les logiciels libres le sont. Généralement, les cours viennent avec une licence de distribution et de modification peu restrictive, souvent une licence Creative Commons[1]. Une application libre de visioconférence conçue pour les profs. À l'ère des MOOC (Massive Online Open Course) et de l'éducation en ligne, posséder une bonne plateforme de visioconférence est essentiel.
Il existe déjà des applications gratuites répondant à ces besoins. Par exemple, le « hangout » de Google + fonctionne très bien. MOOC completion rates. Connexions - Sharing Knowledge and Building Communities. Welcome to OpenWaldorf.com! School of Open. Learn open practices at School of Open. Why "open"? Universal access to and participation in research, education, and culture is made possible by openness, but not enough people know what it means or how to take advantage of it. We hear about Open Source Software, Open Educational Resources, and Open Access… But what are these movements, who are their communities, and how do they work?
Most importantly—how can they help me? A collaboration with the public. Connectivism. Upload and Search Theses and Dissertations - OpenThesis. Connectivism and MOOCs.


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Sometimes it's really hard to get on the Web 2.0 wagon. How do you choose between having conversations on forums, microblogging at Twitter, posting your latest video on YouTube, creating your next podcast, and posting your next small business blog update? Whew! It can be exhausting.
Well, you can outsource some of the work to a virtual assistant or delegate to one of your staff, but where podcasts are concerned you don't need to do either of those. I found a great little tool that does it for you. And for now, it won't cost you a dime.
Odiogo.com is a text to speech conversion site that will automatically turn your blog posts into an audio podcast. Using computer generated voice technology — that's pretty good and can only get better — Odiogo is compatible with all blog engines that publish RSS feeds such as Typepad, Blogger, WordPress or Overblog. You can see it in action by taking a look at my small business tips. Just press the listen now button.
Enroll in the service and within a short time they let you know when the audible version of your blog is ready. The generated MP3 files are even stored on their servers. You don't need to worry about technical integration tasks or bandwidth issues.
Give it a shot and let me know what you think by leaving a comment.


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text: He's taken down terrorists, ninjas, street thugs and corrupt cops, but now, Steven Seagal is after the FBI and-sources close to the subject agree- this time, it's personal. In 2002, the FBI began investigating Seagal under the suspicion that he hired a private detective to scare journalists out of writing negative reviews and now The Glimmer Man is demanding an apology. Seagal genuinely believes, evidently, that if it wasn't for the FBI's troublesome interference, his last twelve movies would have skyrocketed his career, upgrading his status from "that forgettable karate guy who keeps getting fatter" to "Academy Award winning Megastar." Instead, all twelve movies went straight to DVD. I can just picture him now, waiting by his phone and eating Ring Dings. "I'd be fucking Scarlett Johansosn on George Clooney's yacht this very second if it wasn't for that damn FBI..." I can't say I blame the FBI for wanting to destroy his career. It's very possible that Seagal brought these attacks on himself as he's previously boasted that he is both Hard to Kill as well as Above the Law, and you just can't make arrogant, outrageous claims like that and not expect some retaliation; you're really treading On Deadly Ground and putting your career Under Siege. The FBI was simply Out For Justice and you can't slight them for making an Executive Decision. What, just because you're The Prince of Pistols you think that you're Out of Reach of an FBI Attack Force? Guess again, Clementine. ...Half Past Dead.


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Featuring contrast white heart applique details on the front, this sweat top is a fan favorite!
Mix and match the Selja top with any of your favorite bottoms. No matter how brisk the weather gets this fall, she'll stay warm and toasty, thanks to the soft cotton blend fabric that is durable and easy to wash, too. Be sure to add some Limeapple glitter leggings to your cart to go with this cute sweatshirt.


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This museum is quite fascinating but quite difficult for those who do not read Swedish. It appears to be a museum in progress, having staff who are enthusiastic about their...
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3 days in Stockholm
Guide to Stockholm Outdoors
One Day in Stockholm
This museum is quite fascinating but quite difficult for those who do not read Swedish. It appears to be a museum in progress, having staff who are enthusiastic about their subject matter. However, the museum appears to have been started in a wonderful new facility but ran out of money to be completed properly.
The museum if full of items...
A quaint, underrated museum that is interesting and not too big. The current Japan temporary exhibit was well done but a bit too much stuff that wasn't related. Was meant to be mainly about cosplay and indigo subcultures but had a few other random Japanese things thrown in. The link with Swedish cosplayers was a good addition. Other smaller exhibitions...
One of the forgotten museums in Stockholm, or at least little talked about. It's about world cultures, ethnography. Currently there are two temporary exhibitions, Cos-play and Indigo. Both are quite small unfortunately, but gives a brief glimpse of the humans playing cos and the history of denim and the color indigo.
The Museum of Ethnography is located rather inaccessible, at...
I have been there in a different kind of visit, with the "EventGuide" Company, participating in a team building activity. Of course this was not a visit to the museum, but with what I saw from this activity, I loved the rooms where we were doing activities, so I want to go back and visit room by room.
The museum...
This museum houses an impressive collection of artifacts related to indigenous cultures from all over the world. The museum does a great job of showing the different cultures in a positive light without much colonial bias. The museum also has an exhibit on its own collections, showing the difficulty in curating a large collection with so many different classes of...
Review and learn about different ethnic peoples around the world. Even if a lot of the info is in Swedish, there is enough in English to read and understand. My son and I don`t know Swedish, but we had a great visit.
The restaurant is very good too!
After a little walk from Stockholm I got to the museum. It is situated at Museiparken, Djurgården. There are other five museums in total at the park (Tekniska museet, Sjöhistoriska museet, Etnografiska museet, Polismuseet, Riksidrottsmuseet).
The Etnografiska Museet is my favorite of the five and one of my favorites at Stockholm. It is a must visit. Althought if you have...
Some very interesting slices of culture around the world. However, it's mostly in Swedish with little booklets of English translation, away from the exhibits. Also, not terribly well-organized. As a student of culture and anthropology, I was a bit disappointed.
Perhaps the most fascinating piece is the workshop where you can pay just 50skr (~$5) for supplies and make some...
This was a great place to visit, this modern museum is small but it was packed full of exhibits from all over the world.
It's not very 'Swedish' as such, so if you're only in Sweden/Stockholm for a limited time there are probably better things to do.
It's also located beside some free museums such as the Sports museum and...
This museum is staggering - they have so many amazing collections on 2 floors. So varied, not paintings, all other kinds of pieces collected from other cultures. Charming staff who will help you and answer any questions + a decent cafe! Enjoy Stockholm - the Venice of the North!
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Real Estate AuctionFiled under: News on Tuesday, March 29th, 2016 by admin | No Comments
Real Estate Auction
April 30, 2016 at 11:00am
Watts Street, Newark, MO 63458
3 Bedroom, 2 Bath, Modern Home, 1 Acre Lot, Attached 2 Car Garage plus Unattached 2 Car Garage-Shop Building.
Short Line of Personal Property Items!
(2) 3 Wheel Bicyles, 4 Kitchen Chairs, Antique Banjo Choir, Cane Bottom Chair, Wooden Rocker, Small 4 Leg Desk, Afghans, Ceramic Eagle Collection, Kitchen Items, Window Air Conditioner, 3/4 Drive Socket Set, New Steel Posts, Misc. Hand Tools.
Seller: Mr. and Mrs. James Leasman
For Property Viewing call Jim at 573-822-2906


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By PETER KERR
Published: August 19, 1984
John A. Zaccaro, the husband of Geraldine A. Ferraro, the Democratic Vice-Presidential nominee, borrowed $100,000 from an elderly woman whom a court had appointed him to protect and lent the money to his real estate company, Mr. Zaccaro's attorney said late yesterday.
Mr. Zaccaro repaid the loan with interest after a year, according to the lawyer, Morton Povman, a member of the City Council. While Mr. Zaccaro broke no law by taking the loan, Mr. Povman said he told Mr. Zaccaro that he had acted improperly in using the money in his real estate business.
''There is an ethical prohibition known to lawyers: You don't do that,'' Mr. Povman said. Mr. Zaccaro once attended law school but did not finish and is not a lawyer.
Mr. Povman said Mr. Zaccaro had not known that the loan was improper and intended no wrongdoing. Mr. Zaccaro repaid the loan with interest at a rate of 12 percent a year to Alice Phelan, 84 years old, who had been declared incompetent to handle her financial affairs.
''The thing I stress is Zaccaro has not been found to do anything wrong,'' Mr. Povman said.
The Daily News in today's issue reported that Jonathan Weinstein, a court referee who audited Mr. Zaccaro's dealings with the woman's estate earlier this year, questioned the propriety of the loan. A hearing is scheduled on the matter Thursday.
Mr. Zaccaro was appointed conservator of the Phelan estate in December 1982 by Justice Edwin Kassoff of State Supreme Court in Queens. The holdings were mostly in stocks and bank accounts, Mr. Povman said. It was one of three estates Justice Kassoff awarded to Mr. Zaccaro.
Lack of Information Cited
The conservatorships were given to Mr. Zaccaro because he had a reputation as a responsible and successful business executive. In March 1982, Mr. Povman said, Mr. Zaccaro lent $100,000 from the Phelan estate to the P. Zaccaro Company, his real estate business. The lawyer said the court had failed to provide information to Mr. Zaccaro that would indicate such a loan was improper. The loan was repaid in March 1983, Mr. Povman said.
Mr. Povman said he did not know about the loan until Mr. Zaccaro filed an accounting of his activities regarding the Phelan estate ''around March or April'' of this year.
''I said you shouldn't do that type of transaction,'' Mr. Povman said. ''The rule is: Don't intertwine your business interest and those of the estate.''
According to Mr. Povman, Mr. Zaccaro had only intended to help Mrs. Phelan's estate, since it could earn 12 percent interest as a loan to Mr. Zaccaro, rather the 10.5 percent interest it was previously earning. Mr. Povman said Mr. Zaccaro did not benefit from the loan and that he could have just as easily borrowed the money at 12 percent from a bank.
Mr. Povman said he did not know what the loan had been used for.
No Comment by Zaccaro
Mr. Povman said that Mr. Zaccaro had asked him to answer any questions about the loan and that Mr. Zaccaro would not comment directly on the matter. Mrs. Ferraro's press secretary, Patricia Bario, when asked about the loan yesterday, said that she knew nothing about it.
The law secretary to Justice Kassoff, Robert C. Kohm, when reached last night, said the judge would not comment on any ongoing cases. The judge and Mr. Weinstein, the referee, could not immediately be reached for comment.
According to Mr. Povman, Justice Kassoff appointed Mr. Zaccaro as the conservator of two other estates. One, for a another elderly Queens woman, had involved $600,000 and was closed after several months when she died in 1983. Mr. Zaccaro is still managing the $150,000 estate of another Queens woman.
Mr. Povman said Mr. Zaccaro made no loans from the other estates.


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|N-terminally chemically modified protein compositions and methods
|Provided herein are methods and compositions relating to the attachment of water soluble polymers to proteins. Provided are novel methods for N-terminally modifying proteins or analogs thereof, and resultant compositions, including novel N-terminally chemically modified G-CSF compositions and related methods of preparation. Also provided is chemically modified consensus interferon.
|Kinstler; Olaf B. (Thousand Oaks, CA), Gabriel; Nancy Elise (Thousand Oaks, CA), Farrar; Christine E. (Newbury Park, CA), DePrince; Randolph B. (Raleigh, NC)
|Amgen Inc. (Thousand Oaks, CA)
|Filing Date:
|Dec 16, 2009
|Application Number:
|1. A substantially homogenous preparation of N-terminally chemically modified granulocyte colony stimulating factor (G-CSF) or analog thereof, optionally in a pharmaceutically acceptable diluent, carrier or adjuvant, wherein a water soluble polymer attached to the G-CSF N-terminus via an amine linkage.
2. A preparation of claim 1 where said water soluble polymer is selected from the group consisting of dextran, poly(n-vinyl pyrrolidone), polyethylene glycols, polypropylene glycol homopolymers, polypropylene oxide/ethylene oxide co-polymers, polyoxyethylated polyols and polyvinyl alcohols.
3. A preparation of claim 2 where said water soluble polymer is polyethylene glycol.
4. A preparation of claim 3 wherein said polyethylene glycol has a molecular weight of between about 2 kDa and 100 kDa.
5. A preparation of claim 4 wherein said polyethylene glycol has a molecular weight of between about 6 kDa and 25 kDa.
6. A preparation of claim 1 wherein said preparation is comprised of at least 90% N-terminally monopegylated G-CSF or analog thereof and at most 10% unpegylated G-CSF or analog thereof.
7. A preparation of claim 6 wherein said preparation is comprised of at least 95% N-terminally monopegylated G-CSF or analog thereof and at most 5% unpegylated G-CSF or analog thereof.
8. A preparation of claim 1 wherein said G-CSF has the sequence identified in SEQ. ID No. 2.
9. A substantially homogenous preparation of N-terminally monopegylated granulocyte colony stimulating factor (G-CSF), optionally in a pharmaceutically acceptable diluent, carrier or adjuvant, wherein: (a) said G-CSF has the amino acid sequence identified in SEQ. ID No. 2; and (b) said G-CSF is monopegylated with a polyethylene glycol moiety having a molecular weight of about 12 kDa.
10. A pharmaceutical composition comprising: (a) a substantially homogenous preparation of monopegylated granulocyte colony stimulating factor (G-CSF), said monopegylated G-CSF consisting of a polyethylene glycol moiety having a molecular weight of about 12 kDa connected to a G-CSF moiety solely at the N-terminus thereof via an amine linkage; (b) fewer than 5% non-pegylated G-CSF molecules; and (c) a pharmaceutically acceptable diluent, adjuvant or carrier.
11. A method of treating a hematopoietic disorder comprising administering a therapeutically effective dose of a preparation of claim 1.
12. A method of attaching a polyethylene glycol molecule to a granulocyte colony stimulating factor (G-CSF) molecule, wherein said polyethylene glycol molecule has a single reactive aldehyde group, said method comprising: (a) reacting said G-CSF with said polyethylene glycol molecule under reducing alkylation conditions, at a pH sufficiently acidic to selectively activate the .alpha.-amino group at the amino terminus of said G-CSF; and (b) obtaining the pegylated G-CSF and (c) optionally, separating the pegylated G-CSF from non-pegylated G-CSF.
13. A method of claim 12 wherein said polyethylene glycol molecule has a molecular weight of about 6 kDa to about 25 kDa.
14. The peyglated G-CSF product produced by the process of claim 12.
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