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Usage of carbapenems significantly increase the rate of new colonisation due to antibiotic-resistant bacteria in hospitalised patients
Abstract number: O395
Tacconelli E., De Angelis G., Cataldo M., Mantengoli E., Spanu T., Pan A., Corti G., Radice A., Antinori S., Paradisi F., Carosi G., Antonelli M., Rossolini G., Cauda R.
Objectives: Accurate assessment of risk factors for colonisation with antibiotic resistant bacteria (ARB) is often confounded by scanty data on antibiotics use. The aims of the study were: to prospectively define the incidence of new colonisation due to ARB per 1,000 days of antibiotics; to determine mean time of acquisition; to measure patients'risk factors for acquiring ARB; and to compare genotypic patterns of the strains.
Methods: A 12-month prospective multicentre cohort study including all in-patients (pts) starting antibiotics was planned. Samples of nose and rectum were taken before and after starting antibiotics (day 2, 4, 7, 15, and 30). ARB included: meticillin-resistant Staphylococcus aureus (MRSA), vancomycin-resistant enterococci (VRE), and ciprofloxacin-resistant Pseudomonas aeruginosa (CR-PA). Pulsed-field gel electrophoresis was done to define genetic relatedness of the strains.
Results: In total, 6245 swabs from 864 pts were processed. The overall carriage rate of newly acquired ARB was 5%. The mean duration (days±standard deviation) of antibiotic therapy prior to the detection of a new colonisation was 8 (±4) for MRSA (range, 216), 6 (±6) for VRE (range, 219) and 9 (±8) for CR-PA (range, 228). The incidence of ARB per 1,000 days of therapy was 14 for carbapenems, 9 for glycopeptides, and 6 for cephalosporins of 3rd gen. and quinolones. Highest rates were observed for carbapenems in dialysed (29) and diabetic (28) pts and for 3rd gen. cephalosporins in pts with cronic renal impairment (27). Specific rates for MRSA were 8.2 per 1,000 days of macrolides, 7.9 of carbapenems, 3.2 of glycopeptides and 2.4 of cephalosporins. In the multivariate analysis length of hospitalisation >16 days (odds ratio [OR] 2.5, 95% confidence interval [CI] 1.25.1), HIV infection (OR 2.1, 95% CI 1.14.4), use of carbapenems (OR 2, 95% CI 13.8), and age >70 (OR 1.5, 95% CI 1.12) were significant predictors for new ARB acquisition (P < 0.05). All strains were genetically unrelated except for serial isolates from single patient.
Conclusions: The risk of ARB colonisation deeply varies during exposure to different antibiotics and is mainly related to pts underlying conditions and length of hospitalisation. Periodic screening of high risk pts undergoing antibiotics, in particular carbapenems, might be suggested.
Session Details
|Session name:
|18th European Congress of Clinical Microbiology and Infectious Diseases
|Barcelona, Spain
|Presentation type:
|Back to top


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subset: commoncrawl


text:
• Ideal for quality control and GLP applications• Up to 3 decimal place resolution• 1, 2 or 3 point pH calibration• Automatic or manual buffer selection• Multiple language options• Storage of up to 500 results• RS232 connection to printer or PC or infra red (IrDA) communication• GLP compliantThe 3520 dynamic pH/mV meter offers research grade specifications with a comprehensive range of features and functions, making it suitable for the broadest range of research, general laboratory, QC and GLP based applications. The built in data logger can store, print or output readings based on a wide range of trigger options, making this model suitable for monitoring and controlling pH levels.
Jenway Product
Bibby Scientific Limited,
Beacon Road,
Tel: +44 (0) 1785 812 121
Fax: +44 (0) 1785 810 405
Email: email@example.com
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SAN FRANCISCO— Aug. 2, 2007— Andy Schatz, Founder and CEO of Venture Arctic creator Pocketwatch Games, is set to keynote the Austin edition of the CMP Game Group's Game Career Seminar, taking place September 7, 2007 alongside the Austin Game Developers Conference at the Austin Convention Center. In his talk, titled"A Game Industry Journeyman," Schatz will give attendees an intimate look at his career path which took him from intern to CEO over the course of only twelve years. Sponsored by Disney and Activision, in association with GameCareerGuide.com, and programmed by the Game Developers Conference (GDC), the Seminar also features a number of sessions offering practical advice for beginning and intermediate-level game developers wanting to advance and develop their game careers, including the sponsored session on Disney's MMO and virtual world strategy,"Disney's World of Worlds: Where We Came From and Where We Are Headed."
In his talk, Andy Schatz will recount the professional journey he has taken, from his start as an intern at one of the first internet gaming portals in 1995 through his work in the big-budget console world and ending with his move into to the independent game development sector. Schatz is uniquely positioned to offer his experience to Seminar attendees, having founded Pocketwatch Games, creators of the acclaimed indie ecosystem-building game Venture Arctic. Schatz also worked for seven years within the large-scale videogame development world where he wrote the first Xbox Live code to ship to the public. Schatz's first indie title, Wildlife Tycoon: Venture Africa was built over ten months on a budget of $8000 and has sold more than 70,000 copies worldwide.
"Andy's story is every aspiring game developer's dream, so it thrills us that he has agreed to share his experiences with attendees hoping to learn how to achieve comparable accomplishments," said Jane Pinckard, Conference Manager of the Game Career Seminar."We're very proud of the content we've put together for the Austin edition of the Game Career Seminar, and are confident that the students who spend the day with us are going to leave with a stronger toolset to become the game industry's next generation of innovators and leaders."
The Game Career Seminar provides opportunities for students, recent graduates, and those looking to get into the game industry to network with industry professionals, meet with HR executives from leading game companies and learn how to jumpstart their careers. The speaker lineup includes top game developers and industry experts willing to share their perspectives and insights. In addition to the keynote by Andy Schatz, the Austin Game Career Seminar content includes the following sessions:
· Schools Under the Microscope: An Open Q&A
o Representatives from various types of schools that offer degrees in, or related to, game development and design will be on-hand to take questions
· Disney's World of Worlds: Where We Came From and Where We are Headed (Disney-sponsored session)
o Mike Goslin, Vice President, Virtual Reality Studio, Walt Disney Internet Group and Steve Parkis, Vice President, Premium Content, Disney Online discuss the evolution of Disney's MMO and Virtual World strategy, past, present, and future for all levels of game professionals interested in learning more about Disney's game strategy and new career opportunities
· Pitch Your Game Idea
o A panel of industry professionals hears attendees' one-minute pitches and gives the thumbs up or thumbs down to each; everyone is encouraged to participate in this fast-flowing session
· What are Employers Looking for Now?
o A panel of game industry HR professionals sheds light on the industry's latest hiring trends, what companies look for in entry-level candidates, which skills are most sought after, and educates attendees on how best to showcase the skills each is equipped with. This session is followed by a Q&A
· Networking 101
o Darius Kazemi, President, Orbus Gameworks teaches attendees how to talk to anyone, how to be memorable in an industry full of memorable people, and how to increase the value of industry contacts over time
The Game Career Seminar is always run alongside some of the industry's best games-related conferences. Following the Seminar at Austin GDC, CMP Game Group will present a Games Career Seminar at the E for All Expo in Los Angeles, CA October 18th and 19th at the Los Angeles Convention Center.
To register for the Austin Game Career Seminar or for more information, please visit http://www.gamecareerseminar.com.
Contact: Sibel Sunar/Brian Rubin
fortyseven communications
(323) 658-1200
Loria Ryan
CMP Game Group
(415) 947-6287


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- Game Details
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Golden Mullet Awards: Advent Rising
This game is a knock off of so many other titles - but some how they couldnt knock off the fun.
Judgment Day for Advent Rising
The JD hosts try to remain unbiased in their review even though Tommy did the sound and music design.
'Advent Rising' (PC) trailer
'Advent Rising' (PC) trailer
Videos 1–3 of 3


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Members of the Boise City Council are (back, L-R) council members TJ Thomson, Ben Quintana, Lauren McLean, Scot Ludwig (front, L-R) Council Pro Tem Elaine Clegg, Mayor David H. Bieter and Council President Maryanne Jordan.
The Mayor works full-time, managing the day-to-day operations of the City and providing leadership and policy direction to the City Council. The Mayor chairs all meetings of the City Council, voting only in the case of a tie. The six members of the City Council work part-time, holding budget and policy-setting authority for the city. The Mayor and City Council members are elected at large by popular vote. City Council members are elected to a specific Council seat, but the seats are not determined geographically. City elections are held in odd number years (e.g. 2007, 2009, 2011).
Phone: (208) 384-4422
Email the Mayor
Email the City Council
150 N Capitol Blvd
Boise, ID 83702
William L. Bones
Chief of Police
Contact: BPD Media Relations Office
Boise, June 29, 2009 - Boise Police are looking for two men who ransacked and robbed a home in the area of Mountain View Dr & Cole Rd. this afternoon. The victim is an elderly woman who was home at the time of the robbery. The victim was not hurt.
What Happened - Boise Police were called to the home near Cole Rd. & Mountain View Dr at 2:59 p.m. this afternoon. The victim, a woman in her 70's, said she was in her kitchen when two men entered through an open back door. She tells officers she was verbally threatened by one of the suspects to stay seated while the other went to her bedroom and began rifling through her things.
The victim says the suspects left after about five minutes, leaving her bedroom ransacked. At this time, the victim is unable to tell what, if any items were taken. Fortunately, the woman was not hurt.
Suspect's Description - both suspects are described as young men approx. 20- 25 years old. Both were wearing long sleeve shirts and pants. Both have close cropped haircuts, are clean shaven, with tall, slender builds.
Suspect #1 is a white male with blond hair. Suspect #2 is described by the victim as a darker skinned, Hispanic-looking male, well spoken, wearing a dark blue long sleeve shirt and white pants.
The suspects left the house through the same back door they came in. They were last seen on foot.
If anyone has any information about the crime or suspects, they're urged to call Crime Stoppers at 343-COPS.


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Thomas Kent Edlund
Granite, Utah
Beginning Croatian Research
Russian Record Sources
Russian Language and Handwriting
Russian Maps and Gazetteers
Research Horizons: Why and How We Do Family History
Thomas K. Edlund, president of FEEFHS, is a specialist in East European languages and manuscripts. As a professor of family and local history at Brigham Young University, he teaches curricula in East European genealogy, micro-regional history, and paleography.
He has authored many books on language and genealogy, including The Lutherans of Russia, Die Ahnenstammkartei des Deutschen Volkes, Medieval Latin for Family Historians, An Introduction and Index to the German Minority Census of 1939, and A Compendium of Nahuatl Dialectology.
He served as editor of the FEEFHS Journal from 1998 to 2008.
Dave Obee
Saanich, British Columbia
Introduction to Eastern European Research
Germans from Russia
Using Maps and Gazetteers
Writing a Family History
If it's Tuesday, This Must be Lidsbark-Warminski: On the Road in Eastern Europe
Dave Obee is author of Destination Canada, the ultimate guide to Canadian immigration records. He is also author of The Library Book: A History of Service to British Columbia and Making the News, a comprehensive history of Vancouver Island drawn from old newspapers.
Dave is also the co-author (with Sherry Irvine) of Finding Your Canadian Ancestors: A Beginner's Guide, published by Ancestry in 2007. He has compiled seven other books for Canadian genealogical sources, and has given more than 250 talks at seminars and society meetings since 1997.
Dave runs CanGenealogy, a Canadian link site, and Volhynia.com, for those with German ancestry in the northwest corner of Ukraine.
He is one of the owners of Interlink Bookshop and Genealogical Services of Victoria, B.C., which runs the Genealogy Unlimited website.
Dave has visited 19 countries in Europe during 15 visits, as well as Japan and Peru. He has a keen interest in the world war battle areas in France, Belgium and Luxembourg. He served as president of the Federation of East European Family History Societies from 2004 through 2007.
Joe Everett
Provo, Utah
Tracing Immigrant Origins
Online Resources, Part One
Online Resources, Part Two
Introduction to East European Records
Joe Everett is a product manager for European databases at Ancestry.com. Before joining Ancestry, Joe was the head of International Reference at the Family History Library, where he also worked as a cataloger of Slavic and Germanic records. Joe earned a B.A. in Russian Language and in Family History/Genealogy (Germanic emphasis) from Brigham Young University and a Master of Library Science degree from Emporia State University (Kansas). He has served as an officer in the Federation of East European Family History Societies, lectured and published articles on Slavic and Germanic family history and Central & East European historical geography and migration.
Milan Tyler-Pohontsch
Salt Lake City, Utah
German Record Sources
German Language and Handwriting
German Maps and Gazetteers
Milan Tyler-Pohontsch is the owner of European Roots Genealogy. He specializes in German and Eastern European research and translation of old handwritten records. Being of Wendish birth and growing up in Germany he communicates in some of the languages he is specialized in. He is the co-author of a Wendish lineage book and author of the Wendish genealogical newsletter. Milan has an engineer and a masters degree in economics and worked for many years as a manager for one of the leading European hardwood floor producers. More than 15 years ago genealogy became part of his life. He is married in Salt Lake City, Utah and works for the Brigham Young University. Further personal or genealogical information can be found at his website, European Roots.
Sylvie Pysnak
Bountiful, Utah
Czech Language and Handwriting
Czech Record Sources
Czech Maps and Gazetteers
Sylvie Pysnak, AG was born and raised in the Czech Republic. She is currently employed by the Family History Department of the Church of Jesus Christ of Latter-day Saints as a Slavic Research Consultant in the International Research Consultation Unit at the Family History Library.
Sylvie is accredited in Czech research, has a working knowledge of many Eastern European languages and has researched on-site in the Czech Republic, Slovakia and Poland. She has been writing publications and has taught at various conferences since 1998. Sylvie and her husband Bernard live in Bountiful, Utah, and are the parents of four children and the grandparents of two grandchildren.
Daniel Schlyter
Salt Lake City, Utah
Polish Language and Handwriting
Polish Record Sources
Polish Maps and Gazetteers
Daniel M. Schlyter worked at the Family History Library until 2010, where he worked with both International reference and as a U.S./Canada and was the Collection Management Specialist for Eastern Europe, Germany, Scandinavia, and China/Japan. He served as a research consultant on numerous genealogical projects. He has worked as a professional researcher for ProGenealogists. He has experience in Polish, Czech, Slovak, German, Swedish, Hungarian and Jewish genealogy. Daniel served on the Polish Genealogical Society of America board from 1984 to 1999 and on the board of the International Association of Jewish Genealogical Societies from 2000 to 2008. He is a graduate of BYU in International Relations and the Defense Language Institute, Monterey, California in Czech. He also has a certificate from the Foreign Institute of Charles University in Prague, Czech Republic. Daniel has published many articles, books, and finding aids including A Handbook of Czechoslovak Genealogical Research and Essentials in Polish Genealogical Research.
Joanne M. Sher
Duluth, Minnesota
Jewish Research
Holocaust Research
Joanne M. Sher is a professional genealogist and historical researcher who specializes in northeast Minnesota, northwest Wisconsin, American-Jewish research and World War I era records. She has presented numerous times at the International Association of Jewish Genealogical Societies, FEEFHS, and Minnesota Genealogical Society conferences. Her articles have been published in the Federation of East European Family History Societies' Journal, as well as various genealogical society publications.
Todd Knowles
Centreville, Utah
Using the Family History Library
Our venue:
Salt Lake Plaza Hotel at Temple Square
122 West South Temple
Salt Lake City, UT, 84101
(801)-322-5057 Fax
(Ask for the special FEEFHS rate: $82 for single or double, $89 for triple or quad)
Early reservations are encouraged!


text:
Mangrove Equity Partners' second fundraise got off to a fast start with the firm raising more than a half of the fund in just three months.
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text:
JCache to Miss Java EE 7
JSR-107 JCache API co-spec-lead Brian Oliver has announced that "unfortunately we've missed a few of the key delivery dates for JSR-107 to be included in Java EE 7" and "it's only reasonable to notify everyone that it's now highly unlikely JSR-107 will be included in Java EE 7."
Twemproxy – Proxy For MemCached And Redis
Twemproxy is a proxy server that allows you to reduce the number of open connections to your Redis or Memcached server.
Couchbase Releases Couchbase Server 2.0 GA
Couchbase Server 2.0 main features include flexible JSON data model, distributed indexing and querying, incremental map-reduce, and cross data center replication.
Terracotta BigMemory 3.7: Multi-Terabyte Support, Improved Search, Enhanced Security
Terracotta Inc has released BigMemory 3.7, an off-heap store snap-in for Enterprise Ehcache. BigMemory speeds up applications by keeping data in memory, without the long garbage collection pauses that is common for large JVM heap sizes. New in this version is support for multi-terabyte servers, lower search indexing overhead, and enhanced security.
Presentation: Progressive Architectures at the Royal Bank of Scotland
In their presentation posted at InfoQ systems and data architects Ben Stopford, Farzad Pezeshkpour and Mark Atwell show how RBS leveraged new technologies in their architectures while facing difficult challenges such as regulation, competition and tighter budgets. They also need to cope with stringent technical challenges, for instance with efficiency and scalability.
CouchDB versus Couchbase: What are the differences, and what happened to Membase?
Recently Couchbase published a comparison of Couchbase and CouchDB to denote the differences and simlarities between the two. This document addresses a common question: "What is the difference between CouchDB and Couchbase?", and what happened to Membase? InfoQ caught up with James Phillips, a Couchbase founder, to discuss the comparison and the merger of the two products Membase and CouchDB.
Hazelcast 2.0 Released with Off-Heap Storage and Distributed Backups
Version 2.0 of Hazelcast, a Java-based caching, clustering and data distribution solution, has recently been released. As part of this, the product is now offered in both commercial Enterprise and free open-source Community Editions.
MySQL Cluster 7.2 Released with 70x Increased Performance and NoSQL Features
Oracle fires a new round for the heart of the NoSQL market. This 7.2 release of MySQL Cluster has new features putting it head to head with other NoSQL solutions including REST, memcached wire protocol, NoSQL C++, and standard MySQL interfaces. Oracle boasts 70x speed gains for complex queries using MapReduce like distributed joins. Is the world ready for a MySQL/NoSQL hybrid from Oracle?
VMware Releases SQLFire 1.0
VMware releases SQLFire 1.0 a distributed SQL database geared towards high availability and horizontal scalability which offers table replication, table partitioning and parallel execution of queries.
Resin Can Now Act As a Drop-in Replacement for Memcached Solution
With the release of version 4.0.24, the cache for Caucho's Resin Application Server now provides a memcached interface for both the client and the server. This means that Resin can function as a drop-in replacement for memcached solutions.
NoSQL OODB with Smalltalk-based Ruby VM: MagLev 1.0 Released
The MagLev project has released version 1.0 of their Ruby VM. The Ruby implementation is based on the GemStone/S Smalltalk VM which comes with GemStone's distributed cache, ACID transactions, and persistence system (OODB). InfoQ caught up with Monty Williams of the MagLev project to talk about where MagLev fits on the NoSQL spectrum, and much more.
Memcached surpasses EhCache and Coherence in Java Job Demand
Around January 2011, Memcached became the number one caching solution based on Java developer job demand. Memcached expanded beyond its LAMP roots. InfoQ caught up with Dustin Sallings, the implementer of Spymemcached the leading Java Memcached client, to get his perspective on the rise of Memcached in the Java world.
Second Level Caching with Entity Framework
Second Level Caching is one of the features that is not present out-of-the-box in Entity Framework. In an MSDN article "Second-Level Caching in the Entity Framework and AppFabric" Julie Lerman shows how to implement Second Level Caching with Entity Framework to take advantage of caching services like Microsoft AppFabric.
JSR-107, JCache: Alive and Going to be Part of Java EE 7
Distributed caching is the tip of the spear for performance, yet Java does not have a standard API. JSR-107 has gained some notoriety over the years because its old yet not done. Given the increased demand for caching, it seems JSR-107 will finally see the light of day, and be part of Java EE 7. InfoQ caught up with Greg Luck, JSR-107 specification and Ehcache lead developer to discuss.
Windows Server AppFabric adds Read-Through and Write-Behind Support
The new Read-Through and Write-Behind support in AppFabric 1.1 allow developers to improve performance while at the same time reduce the complexity of their applications. This is done by moving the logic for reading from and writing to the database into the caching server itself. Other improvements include lazy-loading of session state information and support for ASP.NET output caching.


text:
Bacteria in the intestine influence motor dysfunction and neuroinflammation in a mouse model of Parkinson's disease.
Researchers Discuss Zika's Effects on Child Development
September 22, 2016|
The National Institutes of Health is hosting a two-day conference on how the virus affects infants and children. The take-home message so far: microcephaly is but one of many potential problems for Zika-exposed fetuses.


text:
Home List of Titles SAR versus S-inc: what is the appropriate RF exposure metric in the range 1-10 GHz? Part I: using planar body models
Please use this identifier to cite or link to this item: http://hdl.handle.net/1959.3/91972
- Title
- SAR versus S-inc: what is the appropriate RF exposure metric in the range 1-10 GHz? Part I: using planar body models
- Author(s)
- Anderson, Vitas; Croft, Rodney; McIntosh, Robert L.
- Abstract
- This is the first of two articles addressing the most appropriate crossover frequency at which incident power flux density (Sinc) replaces the spatial peak value of the specific energy absorption rate (SAR) averaged over 1 or 10 g (i.e., peak 1 or 10 g SAR) as the basic restriction for protecting against radiofrequency (RF) heating effects in the 1–10 GHz range. Our general approach has been to compare the degree of correlation between these basic restrictions and the peak induced tissue temperature rise (ΔT) for a representative range of population/exposure scenarios. In this article we particularly address the effect of human population diversity in the thickness of body tissue layers at eight different sites of the body. We used a Monte Carlo approach to specify 32000 models (400 models for each of 8 body sites for 10 frequencies) which were representative of tissue thicknesses for age (18–74 years) and sex at the eight body sites. Histogram distributions of Sinc and peak 1 and 10 g SAR corresponding to a peak 1 °C temperature rise were obtained from RF and thermal analyses of 1D multiplanar models exposed to a normally incident plane wave ranging from 1 to 10 GHz in thermo-neutral environmental conditions. Examination of the distribution spread of the histograms indicated that peak SAR was a better predictor of peak tissue temperature rise across the entire 1–10 GHz frequency range than Sinc, as indicated by the smaller spread in its histogram distributions, and that peak 10 g SAR was a slightly better predictor than peak 1 g SAR. However, this result must be weighed against partly conflicting indications from complex body modeling in the second article of this series, which incorporates near-field effects and the influence of complex body geometries.
- Publication type
- Journal article
- Research centre
- Swinburne University of Technology. Faculty of Life and Social Sciences. Brain Sciences Institute
- Source
- Bioelectromagnetics, Vol. 31, no. 6 (Sep 2010), pp. 454-466
- Publication year
- 2010
- FOR Code(s)
- 06 Biological Sciences; 09 Engineering
- Keyword(s)
- Fat thickness; Human body modeling; Power flux density; Radiofrequency safety standards; SAR; Skin thickness; Specific energy absorption rate; Temperature
- Publisher
- John Wiley & Sons
- 0197-8462
- Publisher URL
- Copyright
- Copyright © 2010 Wiley-Liss, Inc.
- Additional information
- The authors acknowledge support from the Mobile Manufacturers Forum and the GSM Association under Work Package 4 of the phase I RF Dosimetry Program.
- Peer reviewed


text:
Unitary Group is denoted .
Theorem: for any positive integer n, is isomorphic to .
Q: Prove that every element is determined by ; meaning, results in a well-defined automorphism of .
A: let be arbitrary. Then is an isomorphism. So, to show if something is well-defined I need to show if a=c, b=d, then a*b=c*d. I am not sure what to my a,b, and c's are. I know . so, do I let and . Now, I want to show ?
Unitary Group is denoted .
I think that your analysis of the problem is a little bit too complicated. For an easy example, let us look at the group . If is an automorphism, it must send a generator to a generator. To be explicit, a number is a generator of if and only if . In our case, is a generator if and only if . This means that . So, we have the following possibilities: , , , , or . If you try composing these maps, you will find that you recover the multiplication table for your .
Give it a try. Good luck!


text:
Toxicokinetics - Powering Silicon Valley | San Jose State UniversityBook 2.57 MB | Ebook Pages: 82
Toxicokinetics • Classic Toxicokinetics Classical Toxicokinetics • One Compartment Model • Log Plasma Conc vs. Time • 1st order process – Elimination
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Factors affecting an individual's response to a toxic chemical ► The dose ► Uptake into the body (absorption) ► Movement within the body (distribution)
GLOSSARY OF TERMS USED IN TOXICOKINETICS - IUPAC - InternationalBook 6.77 MB | Ebook Pages: 118
Glossary of terms used in toxicokinetics (IUPAC Recommendations 2003) Abstract:This glossary contains definitions of 365 terms frequently used in the
Guideline for Industry - U S Food and Drug Administration Home PageBook 2.29 MB | Ebook Pages: 64
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S 3 A Toxicokinetics: A Guidance for Assessing Systemic ExposureBook 3.53 MB | Ebook Pages: 181
Toxicokinetics may involve exposure assessment of dams, embryos, foetuses or newborn at specified days (Note 14). Secretion in milk may be assessed to define its
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Chapter 3 Toxicokinetics ANDREW G. RENWICK 3.1 INTRODUCTION The sequence between exposure to a chemical and the generation of an adverse effect can be divided into
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Toxicokinetics: For fertility studies: In-life observations: Terminal and necroscopic evaluations: OR For embyrofetal development studies: In-life observations:
Lecture 6: Fundamental Principles of Toxicity, ToxicokineticsBook 6.96 MB | Ebook Pages: 77
ES/RP 532 Applied Environmental Toxicology Page 1 of 25 ESRP532 Lecture 6.doc Fall 2004 September 20, 2004 Lecture 6: Fundamental Principles of Toxicity
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TOXICOKINETICS: AN IMPORTANT TOOL IN NEW DRUG DEVELOPMENTBook 4.96 MB | Ebook Pages: 54
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TOXICOKINETICS AND EFFECTS OF PCBs IN ARCTIC FISH: A REVIEW OFBook 5.25 MB | Ebook Pages: 214
38 E. H. JØRGENSEN ET AL. Major atmospheric, riverine, and marine pathways have resulted in long-range transport of contaminants into, and within, the Arctic.
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Methods for Assessing the Effects of Mixtures of Chemicals Edited by V. B. Vouk, G. C. Butler, A. C. Upton, D. V. Parke and S. C. Asher (jJ 1987 SCOPE
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Toxicokinetics should be incorporated appropriately into the design of the studies. It may consist of exposure profiling or monitoring (Note 1) at appropriate dose
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toxicokinetics of BPA in animals and humans would have no implication for the EFSA 2006 risk assessment of BPA. Toxicokinetics of Bisphenol A
This work is licensed under a Creative Commons AttributionBook 6.58 MB | Ebook Pages: 103
Toxicokinetics is the quantitation of the time course of toxicants in the body during the processes of absorption, distribution, biotransformation, and
Chlorine - ATSDR HomeBook 6.1 MB | Ebook Pages: 126
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236 IARC MONOGRAPHS VOLUME 95 4. Mechanistic and Other Relevant Data 4.1 Toxicokinetics 4.1.1 General considerations The toxicokinetics of inhaled compounds is
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toxicokinetics, and dose ranges where metabolic induction, saturation, or nonlinearity between external and internal doses does or does not occur;
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2.1.1 Overview on toxicokinetics, metabolism and distribution Formaldehyde is present at low levels in most living organisms. Physiological amounts of


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Hi! The church bells were ringing and I ran outside to catch the last bit of daylight, and wished I were a sailor so I could sail to places in the world where it's not already night when the clock strikes 6!
Dress: Ashley sailor dress
Hansel from Basel over-the-knee socks
Vintage woven loafers
For more please visit: http://fashionforwriters.com


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If the Navy picks you to operate a nuclear reactor located in a submarine hundreds of feet below the ocean's surface, you're presumed to be a responsible sort. But from time to time, a young sailor stationed at the West Milton training site of the Knolls Atomic Power Laboratory gets in trouble. Most often, it's for the kind of indiscretion that gives us oldsters a twinge of nostalgia. The kind of thing that reminds us ...
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{if segment_3 == 'live_timing'}{/if} {if segment_3 == 'live'}{/if}
Zatopkova 100/2
160 17
Czech Republic
Lenka Kovarova
Secretary General
Antonín Bauer
00420 242 429 259
The 2009 ITU Duathlon World Championship title went to triathlon regular, Vendula Frintova of the Czech Republic who used her kick to nip Sandra Levenez of France by four seconds in an exciting finish. Ana Burgos of Spain was third. Frintova finished in a time of 2 hours 18 minutes and 18 seconds. Levenez produced the fastest opening 10-kilometre run of the day, as she and Samantha Warriner of New Zealand pressed the pace early one. A 40k bike in and out of the Lowe's Motorspeedway didn't provide much drama with one large group coming together and staying together; the athletes were just waiting for the final five kilometre run. And it did come down to the run, with the top nine second run splits exactly matching the order of finish for the top nine athletes. Frintova's 15:57 was the fastest though and gave the Czech athlete her first world title. "I'm really, really happy. I'm a specialist for triathlon, but my season was up and down. This is my best result for the year," said Frintova. "The race was really hard, especially the first run for me. I was suffering. I didn't really expect to be the fastest at the end. The bike was quite calm, no one wanted to go hard, so we were just sitting back and waiting for the second run." Evgenia Sukhoruchenkova of Russian claimed the Under23 women's championship, followed by Kinga Lauf of Hungary. Great Britain's Sophie Coleman was crowned world junior duathlon champion with teammate Vicky Graves in second. Marjon Van Der Wansem of the Netherlands finished third. {/exp:tagstripper:tagsToSave}
Long Distance Triathletes get your entries in for the ITU Long Distance Series points race in Sadska Czech Republic Date: Saturday, July 16, 2005 Venue: Sadská, 40 km from Prague Status: International triathlon race, 11th year, race of the ITU Long Distance Tri Tour 2005 and 3rd race of the Czech cup in long distance triathlon Distances: Swim race 3 km Bicycle race 80 km Run race 20 km Details can be found at http://www.czechman.cz {/exp:tagstripper:tagsToSave}


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1,258 acres along the Huron River providing recreation of many types. Visit Turtle Cove Aquatic Center featuring two water slides, kid's sprayscape with 300-gallon dumping bucket, endless lazy river and zero-depth entry pool with lap lanes. Enjoy picnicking, basketball, volleyball, tennis courts, 18 hole, par 3 golf course, canoeing, bike rental and a paved five mile hiking/biking trail. Have fun ice skating and x-country skiing during the winter. This course is a certified member of the Turfgrass Environmental Stewardship Program.
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To everyone who reads the blog, everyone who comments, all our guest bloggers, anyone who happens to see this — my best wishes for a warm and happy holiday season, and a terrific 2014. Changes have been gathering force in classical music, and I hope we'll all track them here, with hope and joy. My warmest thanks to everyone in this blog community, and everyone working for classical music's rebirth. We're all in this together, and together we can work miracles. I'm grateful to all of you. … [Read more...]
Archives for 2013
Brush the issues aside
Here's a thought from my friend and Juilliard colleague David Wallace, a violist, composer, teaching artist, and — as Doc Wallace — a Texas fiddler. And much, much more. His subject? All the issues he, I, and so many others thrash out, about classical music, its problems, its future, its place in our culture. Everything discussed in my blog. At some point…but let David tell it: At some point, self-marketing that surfs the "What's wrong about classical music wave, and why I'm not that" is going tobe blown away by marketing that simply … [Read more...]
American Voices, footnotes and letdown
Followup to my post on Renée Fleming's American Voices festival at the Kennedy Center (which featured classical, pop, jazz, country, Broadway, and gospel singing): Pop, jazz, and classical singers have some of the same problems. As I said in my previous post, I couldn't attend the masterclass for classical singers, which Eric Owens taught. But Anne (Anne Midgette, my wife, who did attend, and reviewed the festival for the Washington Post) said he told the students not to pump out a big operatic sound, but instead to build meaning from the … [Read more...]
The walls are coming down
That's a phrase you might have seen me use, when I've talked about closing the gap between classical music and the rest of our culture. But the person who said those words at the Kennedy Center in Washington the weekend before Thanksgiving ago wasn't me. It was Renée Fleming, who of course is one of the most famous classical musicians alive, and who's knocked down walls herself by recording albums of jazz (here, here) and even indie rock. She used the phrase at the Kennedy Center because she was knocking walls down again, this time by … [Read more...]
Instead of a press release…
A colleague teaching an entrepreneurship course at a major music school emailed this question: I'm planning my entrepreneurship class for the spring and I used to have an exercise (using your blog actually) that required students to write a press release. This now seems kind of futile to me, since press releases, well, they are so analogue. Do you have any ideas about what I could replace this with? I like the notion of students having to publicize (and articulate) their projects. Blog post? Personal letter? Here's how I answered: You're … [Read more...]
From Erica Sipes: Twitter in the concert hall?
From Greg: Erica helps us here with a question many of us ask. If we break the traditional silence of the concert hall — and the sitting motionless that goes with it — will people still listen with the care and attention we expect? You'll see that she herself wondered about this, but by taking part in something she'd never tried before, she learned… But let her tell you. I almost always play the role of the "good girl" but a few weekends ago I found myself in a position where I was being glared at with obvious distaste and disgust within the … [Read more...]
From Victoria Paterson: Filling the house for new music
From Greg: Victoria will explain how she and I happened to meet, and strike sparks from each other. What excited me was the large audience she gets for the American Modern Ensemble, the new music group she runs with her composer husband, Robert Paterson. I fear I can be a broken record on the subject of audience, but I'm not going to stop saying that classical music needs new listeners. At new music concerts I'm saddened by seeing only 20 or 30 people in the audience, or seeing a repeating group of insiders, And I'm saddened, too, when I hear … [Read more...]
Again, where's Greg?
It's been liberating, I have to confess — not writing the blog for a bit, while I keep up my intense travel schedule. New York (from Washington) every week, and then, from the second week in October, a trip to DePauw University to continue my work with the music school there, a trip to Dubuque to help a community music school evolve a strategic plan. And then Boston to speak (twice) at a conference (and serve on a panel). And last week DePauw again, and this week Los Angeles. There I'll be joining Doug McLennan, founder of ArtsJournal and my … [Read more...]
From Jeffrey Nytch: The entrepreneurial symphony
From Greg I've been in email touch with Jeff Nytch for a few years. We have a mutual close friend, and of course a shared interest in teaching entrepreneurship at music schools. Last spring, Jeff invited me to speak at the University of Colorado-Boulder, where he runs the music school's entrepreneurship program. But what Jeff writes about here goes beyond any friend-of-friendship, or any speaking engagement. Jeff is not just an entrepreneurship teacher. He's an entrepreneur, and tells us here how he used entrepreneurship — defined much more … [Read more...]
Where's Greg?
I've been dashing about. Two weeks ago — and twice since the start of September — I've been at the DePauw University School of Music, plunging into my intensive consultantcy, working with faculty, students, and the dean to help define the school's radical new curriculum. And last week I was in Dubuque, IA, helping the Northeast Iowa School of Music — a spirited community music school — evolve a strategic plan for future growth. This turned out to be as gratifying as my DePauw work. They're terrific people in Dubuque, and to judge from the … [Read more...]
Monday post — recanted rant
From the New York Times Book Review a week ago, a Q&A with Scott Turow: What was the last truly great book you read? When I noticed that Patti Smith's "Just Kids" had won the National Book Award for nonfiction in 2010, I ranted about contemporary culture, so celebrity-besotted that we were now giving vaunted literary prizes to rock stars. Then I read the book. It is profound and unique, a perfectly wrought account of what it means to give your life to art and to another person. I expect it to be read with wonder for a long … [Read more...]
Timeline of the crisis
Here — to end my posts on the dates of the classical music crisis — is a detailed crisis timeline. The information in it comes from many sources, including published reports, blog comments by people who saw the crisis develop in their professional work, and my own experience. Nobody should think this timeline is anything but tentative. It's just a beginning of the timeline we could eventually construct, with more data and more reports from people in the middle of it all. And this timeline, tentative as it is, has some obvious weaknesses. … [Read more...]
Timeline of the crisis (2)
The first of my timeline posts offered two snapshots of classical music coverage in Time magazine — which declined (a lot) in recent decades. That shows us classical music receding from mainstream culture. Or mainstream culture moving away from classical music. Now, in my second timeline post, I'll quote an overview of the crisis from Ron Nadel, who posted it as a comment to the first of the posts I've been doing on the classical music crisis, the one where I asked how long the crisis has been going on. Note that it's based on his own … [Read more...]
Timeline of the crisis (1)
I'm continuing my posts about the classical music crisis, and I'm coming now to the crisis timeline, which will how and when the crisis developed, decade by decade. I started these posts by asking when the crisis began. Here are some answers, in three parts. First, two snapshots. Then, tomorrow, a savvy overview, written as a comment to my original post. And on Thursday a detailed timeline. Two snapshots. First: a graph showing mentions of the word "orchestra," tracked year by year through every issue of Time magazine from its founding in … [Read more...]
Monday post — Philadelphia fun
Many of us know that the Philadelphia Orchestra couldn't kick off Carnegie Hall's season, as planned, because of a brief strike by Carnegie's stagehands. Their concert was cancelled. So what did they do? They gave a free concert -- dressed in colorful, informal clothes — in their hall in Philadelphia. 2200 people showed up. And clearly had fun. Before the concert, there was a conducting competition. For members of the audience. A nine year-old won, and -- what a prize for a contest winner — conducted the orchestra in the end of … [Read more...]


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Fort Myers Sailing Club
The Fort Myers Sailing Club meets on the first Wednesday of every month at the Cantina Sol (MarinaTown Plaza) located just over the US 41 Bridge west of 41, Meetings begin at 7:30 PM. Guests are always welcome! Food and beverages are available for purchase.
The Fort Myers Sailing Club sponsors numerous events throughout the year. The club sponsors cruises as well as racing.
Cruises are usually informally planned with a designated cruise leader. Southwest Florida offers almost endless opportunities for local cruising from the Keys to Sarasota. Join our experienced cruisers or lead a cruise yourself!
Races are held in the Caloosahatchee River between the US 41 and Mid-Point Bridges every month from October through May. Races are non-spinnaker using a PHRF-style local handicapping system. Races are open to member and non-members for a small annual entry fee.
Further racing information and a calendar of races are available her(click on link) as well on this website.
The Fort Myers Sailing Club publishes a monthly newsletter titled The Sloop Poop - Scoop. The newsletter is generally mailed to the all members and published on this website.
Please feel free to browse our website. If you have any questions or would like to join our organization, you may download a
membership application
by clicking on this link or at the bottom of the Contact Us page you may also find another link.
About Us
The Fort Myers Sailing Club (FMSC) was formed in the mid-1950's by a group of local downtown businessmen who founded the club with the idea of promoting youth sailing in the area as well as bringing people from all walks of life together to share in their common interest of sailing. Even some fifty years later, Fort Myers Sailing Club members are still devoted to the concept upon which the club's forefathers founded it, with the most important one being: keeping the sport of sailing alive in our community.
Today, the Fort Myers Sailing Club membership roster is comprised of some of the most active and experienced sailors in Southwest Florida. The club's activities span the entire calendar year with a one-day-a-month racing program over the course of six to eight months, as well as several cruises taking the cruisers to destinations from the Florida Keys to Sarasota and beyond.
The Sloop Poop - Scoop is the official newsletter of the FMSC. The Sloop Poop - Scoop provides members with news of the monthly meeting proceedings, upcoming race and cruise information, race results and articles on recent cruises and other information which might be of value to the members. Members are encouraged to submit articles and photos on anything related to the clubs activities or mission to our Webmistress Shari at: firstname.lastname@example.com.
Throughout the years, FMSC has brought together numerous people who share in the enjoyment of the sport of sailing. Through a variety of activities such as social events, racing regattas, and cruises, members and guests keep the club alive and active.
Come join us to find out all the fun you've been missing!
Club Officers for 2016
Walter Smith
Board of Directors:
Vice Commodore:
Arnie Pfald
Bill Scarpitta Bruce Schvenski
Paul McDill
Joe Martinez
Cruise Director:
Bruce Schvenski
Committee Boat:. Dan Lancaster Rick Lancaster
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Drinking Water Criteria Document for Aldicarb (Final Draft)
The Office of Drinking Water (ODW), U.S. Environmental Protection Agency has prepared a Drinking Water Criteria Document on aldicarb. This Criteria Document is an extensive review of the following topics: Physical and chemical properties of aldicarb; Toxicokinetics and human exposure to aldicarb; Health Effects of aldicarb in humans and animals; Mechanisms of toxicity of aldicarb; Quantification ot toxicological effects of aldicarb.
Risher, J. Drinking Water Criteria Document for Aldicarb (Final Draft). U.S. Environmental Protection Agency, Washington, D.C., EPA/600/X-84/189-1 (NTIS PB86117751).
This download(s) is distributed solely for the purpose of pre-dissemination peer review under applicable information quality guidelines. It has not been formally disseminated by EPA. It does not represent and should not be construed to represent any Agency determination or policy.


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About Rainier
PC gamer, WorthPlaying EIC, globe-trotting couch potato, patriot, '80s headbanger, movie watcher, music lover, foodie and man in black -- squirrel!
'City of Heroes' - Screens
by Rainier on July 3, 2003 @ 1:15 p.m. PDT
City of Heroes is the first superhero themed online RPG and will offer a host of exciting and compelling gameplay features. Players create their own heroes, choosing from hundreds of different powers, skills, abilities, and items and design their own unique costumes. Then they can band together with other players to fight evil, build their own secret headquarters and strive to become the premiere hero group in the city.


text: Thanks for visiting our website! We are a family-run business and re-sell Trader Joe's products, among other items such as seasonal countdown calendars. To be clear, we are not affiliated in any way with Trader Joe's, we just love their products and want to make them available to those who do not have a Trader Joe's retail store nearby. Visit About Us for more about our store.


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The group behind a ballot measure to restore Alaska's Coastal Management Program says initiative opponents are violating state campaign disclosure law.
The Alaska Sea Party points to the "Vote No on 2" campaign's TV ads, which feature outdated information about the group's top three contributors, and don't audibly name those donors as required by the law.
At the time the ads were produced No on 2's top three financial backers were the Alaska Miners Association, Shell Oil Company, and the Alaska Oil and Gas Association. Since then, ExxonMobil and ConocoPhillips have displaced Shell and AOGA on the group's website, but not in the ads.
Sea Party Policy Director Lisa Weissler want the ads changed or taken off the air.
"The ads should stop. It's a very clear violation of the law, and so it should stop or they should do it right. And they should have penalties assessed," Weissler says.
She says the Sea Party filed a complaint about the ads with the Alaska Public Offices Commission Friday.
It's the second APOC complaint the Sea Party has filed against the anti-Measure 2 group. In July, the Sea Party took issue with the "Vote No on 2" moniker, saying it violates a state requirement that a group's name reflect an issue or the goal, and not simply express opposition or support of a particular measure.
The Sea Party touts itself as a grassroots organization. Its top three contributors are the North Slope Borough, Bristol Bay Native Corporation, and the Alaska Conference of Mayors.
No on 2 spokesman Willis Lyford could not be reached for immediate comment.
The federal Coastal Zone Management Act allows states that adopt an approved coastal management program to have greater input into development decisions along their coastlines. It also streamlines the regulatory process of various local, state, and federal agencies.
Alaska had a program for more than 30 years. But the legislature and Parnell administration failed to reach a deal to reauthorize it in 2011.
Measure 2 will be on the August 28th primary ballot.
Recent headlines
Money management at Mental Health Trust raises concernsLegislators are considering a special audit of the Alaska Mental Health Trust and how the trustees are investing its money.
Alaska Alcohol and Marijuana Control Office director resignsCynthia Franklin, who helped guide Alaska's work in setting up the state's legal marijuana industry, is resigning as director of the Alcohol and Marijuana Control Office.
Accusations of fake news and Islamophobia fill Anchorage AssemblyAn online controversy spread to the halls of city government in Anchorage on Tuesday, with accusations flying about fake news, liberal media bias and a militant Islamic training camp in Wasilla that does not exist.
John Glenn, first American to orbit the Earth, dies at 95Former Sen. John Glenn has died at 95. After a career as a Marine pilot, Glenn was chosen as an astronaut. He was the third American in space.


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Policy cancellations: Obama will allow old plansAP Photo
President Barack Obama speaks about his signature health care law, Thursday. Bowing to pressure, President Barack Obama intends to permit continued sale of individual insurance plans that have been canceled because they failed to meet coverage standards under the health care law, officials said Thursday.
WASHINGTON Bowing to pressure, President Barack Obama on Thursday announced changes to his health care law to give insurance companies the option to keep offering consumers plans that would otherwise be canceled.
The administrative changes are good for just one year, though senior administration officials said they could be extended if problems with the law persist. Obama announced the changes at the White House.
This fix wont solve every problem for every person, but its going to help a lot of people, the president said.
He acknowledged that we fumbled the rollout of this health care law and pledged to just keep on chipping away at this until the job is done.
He also promised to work to regain the trust of the American people.
I think its legitimate for them to expect me to have to win back some credibility on this health care law in particular and on a whole range of these issues in general, he said.
Obama has been under enormous pressure from congressional Democrats to give ground on the cancellation issue under the health care overhaul, a program likely to be at the center of next years midterm elections for control of the House and Senate.
Its unclear what the impact of Thursdays changes will be for the millions of people who have already had their plans canceled. While officials said insurance companies will now be able to offer those people the option to renew their old plans, companies are not required to take that step.
The main industry trade group, Americas Health Insurance Plans, said Obamas offer comes too late and could lead to higher premiums, since companies already have set 2014 rates based on the assumption that many people with individual coverage will shift over to the new markets created under Obamas law.
Karen Ignagni, president of the industry group, didnt speculate on whether companies would extend coverage for those threatened with cancellation, but warned in a statement that changing the rules after health plans have already met the requirements of the law could destabilize the market and result in higher premiums for consumers.
Insurance companies will be required to inform consumers who want to keep canceled plans about the protections that are not included under those plans. Customers will also be notified that new options are available offering more coverage and in some cases, tax credits to cover higher premiums.
Under Obamas plan, insurance companies would not be allowed to sell coverage deemed subpar under the law to new customers, marking a difference with legislation that House Republicans intend to put to a vote on Friday.
Only last week, Health and Human Services Secretary Kathleen Sebelius told a Senate panel she doubted that retroactively permitting insurers to sell canceled policies can work very well since companies are now in the market with an array of new plans. Many have actually added consumer protections in the last three-and-a-half years.
Republicans were unimpressed with the changes.
House Speaker John Boehner, speaking in advance of the presidents announcement, insisted it was time to scrap this law once and for all.
While the White House deals with the cancellation issue, the administration is also promising improvements in a federal website so balky that enrollments totaled fewer than 27,000 in October in 36 states combined. The administration had said in advance the enrollment numbers would fall far short of initial expectations. After weeks of highly publicized technical woes, they did.
Adding in enrollment of more than 79,000 in the 14 states with their own websites, the nationwide number of 106,000 October sign-ups was barely one-fifth of what officials had projected and a small fraction of the millions who have received private coverage cancellations as a result of the federal law.MORE IN Wire NewsMADISON, Wis. Full StoryKABUL, Afghanistan Afghanistan has fallen so far from Americans consciousness that some may... Full StoryCHARLESTON, S.C. Full Story
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Emma Hughes
- AP-BDC Certified
Project Manager, LEED, U.S. Green Building Council
Emma is an Associate in the LEED Department at USGBC. She works to support
departmental operations and coordinates multiple LEED committees made up of volunteer experts, including the LEED Steering Committee, LEED Advisory
Committee, Technical Committee, six Technical Advisory Groups, and various
working groups.
Before coming to USGBC, Emma lived in Sydney, Australia for ten months and
taught English as a second language to immigrants and international students.
She became passionate about sustainability while she was earning her B.A. in
International Relations from Boston University.


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An experience in any weather
At the Cologne Zoo more than 10,000 animals have found a new home - as many as in no other zoo in Germany. Visit okapi, lemurs, alpacas, african marabou, birds of paradise, tapirs and many other animals - in one of the oldest and at the same time one of the most modern zoos in the world!
Opening Hours:
In summer (from 1 March to 30 October): 9:00 a.m. to 6:00 p.m.In winter (from 31 October to 28 February): 9:00 a.m. to 5:00 p.m., aquarium to 6:00 p.m.
Admission Prices:
adults: 15.00 €children (4 to 12 years): 7.50 €students: 10.00 €
Cologne Zoo


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HON 210 Series vertical files are America's record-holders. You can see and feel the quality in the ball-bearing suspensions. Plus, there's quality you can't see, like six inner steel uprights, and a double-walled kick plate. Look to 210 Series verticals for durability and great standard features.
Assembly Type: Fully Assembled
Counterweight: No
Gross Weight: 114.0 lbs.
Lock: Yes
Overall Depth: 28.5"
Overall Height: 52.0"
Overall Width: 15.0"
Units Per Package: 1
Ability to Key-Alike: Yes
Document Size Accommodation: Letter
Drawer Configuration: File/File/File/File
Drawer Depth - File: 28.0"
Drawer Quantity Available: 4
Drawer Suspension - File: Ball-Bearing
Hangrail Options: Front-to-Back
Pull Style: Bright Aluminum Drawer Pull


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Police searching for two gunmen
MARTINSBURG – Police say a 25-year-old Martinsburg man died after being shot Monday night during a struggle with two gunmen outside an apartment in the city, and they are asking the public's help in locating the two suspects believed to be involved.
Police identified the victim as Spencer Lee Vancamp, who resided at an apartment located at 314 Pendleton Drive.
At about 11:46 p.m. Monday, members of the Martinsburg Police Department were dispatched in reference to a shots fired call. As officers were arriving, dispatchers reported that a gunshot wound victim was located at the Berkeley Medical Center, according to a news release.
In the area of 314 Pendleton Drive, officers located multiple shell casings laying on the ground. Police were able to speak with witnesses, who said that the victim and another man had gone to a local convenience store and returned to the residence on Pendleton Drive.
When they returned, both men were approached by two unknown black males displaying handguns. The men attempted to walk with them into the residence, but instead took them to an adjacent apartment, police said.
When the residents of the adjacent apartment opened the door, they saw the men with firearms and promptly shut the door. At that point, one of the suspects fired a round at the door, police said.
A struggle then ensued with the four men, which resulted in the victim being shot in the upper and lower torso. The second male fled from the area, while both suspects fled to a nearby vehicle. Following the shooting, the victim was taken to Berkeley Medical Center for treatment.
Once at the Berkeley Medical Center, the victim succumbed to his injuries. An autopsy is scheduled for today in Morgantown.
The Martinsburg Police Department is asking the community's assistance in locating both suspects in the incident. Both males were described as black males approximately 6 feet tall. The suspects' vehicle is described as a silver sedan with dark tinted windows.
Anyone with information is urged to contact the Martinsburg Police Department at 304-264-2100.
Monday's fatal shooting is the second homicide that has occurred on Pendleton Drive this year. On Aug. 21, a Martinsburg woman was allegedly beaten to death inside her apartment on Pendleton Drive by her husband.
The victim's husband, Rickie Greenfield Jr., 30, was charged with one count of murder in connection with the slaying of his wife, Jill, and has since been indicted.
– Staff writer Edward Marshall can be reached at 304-263-8931, ext. 182.


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This should help the team play better and ease the players' minds knowing they're not about to be traded resulting in better chemistry.
I think this shows that our backroom staff must be confident in Baron Davis' ability to return and contribute. It's obvious that we have a deep team but currently 0 depth at the PG spot. Unless Baron comes back and plays.Glen Grunwald is not looking at dramatic ways to upgrade the Knicks.
As a GM, youre always looking to improve the team but I dont foresee any further changes at this time, Grunwald said before the game Friday. Well see how it all plays out but were hopeful that this group will come together and play basketball and hopefully exceed expectations that were set for them at the beginning of the year.
With the addition of J.R. Smith, the Knicks appear to have one of the deepest rosters in the league.
Mike and I have been working together, along with our staffs, to get this team where it needs to be, Grunwald said. I know expectations were high and we had high expectations too. So Mike and I are focused on trying to get this situation as good as it can be, so we can have the best team that we can have and thats all weve been worried about so far.
If they weren't confident in that happening I'm sure they'd be looking to deal for a PG. We all know Mike needs his PG's.
This should help the team play better and ease the players' minds knowing they're not about to be traded resulting in better chemistry.
If an impending trade doesn't involve Dwight, please let there be no trades for the team this year.
Grunwald really has done everything right this year imo.
For all we know he could be lying. But at least he is making the players not constantly think they are going to be cut or traded.
The Knicks should be done and as long as they don't have an implosion Grunwald will likely win GM of the year awards. He had a rocky start but the Knicks went from no depth to a team who might have the best team talent wise from 1-7 (Melo, Amare, Lin, JR, Tyson, Fields, Smith). On top of that the majority of the team is either young or in their primes.
That is definitely a dark horse championship contending team ala the 99 Knicks.
Amare is past his prime
The thought of Interim GM Grunwald talking/working with Mike Dantoni on
what is best for this Knicks team should make all Knicks-Fans ready to....
The Knicks not going after 2nd season PG-Ishmeal Smith speed/passing-skills
to workout in practice with Jeremy Lin under Melo/Stat/Tyson tutorship....
or sign veteran PG-Arron Brooks over SG-JR Smith....shows how bad our Knicks
scouting report on NBA players has been with Grunwald & Dantoni at the helm.
The Knicks has been getting great outstanding performance from SG-Fields
and SG-Shump on offense/defense in the 4th quarter of the past 10 games....
what will the addition of a 24 minute playintime SG-JR Smith do to the performance
and playingtime of Fields/Shump?
Baron Davis NBA career has always been a halfcourt offensive guard....
Blake Griffin has tripple the highlight fastbreak dunks/alley-oops with CP3 in
20 games than he had in a full season with Baron Davis.
What grade do u give interim GM Grunwald after owner Dolan amnesty PG-Billups
to sign C-Tyson Chandler? both signing of PG-Bibby & PG-Baron Davis were
Grunwald selection to add nothing to the team in 31 games.
I was a big advocate for Ish smith but if the baron recovery stories are true then he would have been buried on the bench. Also Arron Brooks is a RFA meaning the suns QO is higher than any team can offer right now. Also JR smiths shooting ability will help the knocks against Zone defenses like the one the hornets used Friday to beat the Knicks. So yeah thats why it works.


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Tag Archives: Healthy Heavenly Foods
Bancroft Way food trucks' days are numbered
Berkeley's Bancroft Way won't have food trucks for much longer.
The permits that authorize Dojo Dog, Healthy Heavenly Foods and Kettle Corn Star, which are currently parked at the intersection of Bancroft and College Avenue, will expire March 31, 2016. The city does not plan to renew any of the permits. … Continue reading »
New Berkeley home found for displaced food trucks
Three food truck vendors who were displaced by UC Berkeley's construction at Sproul Plaza have been found a new location at the corner of Bancroft and College. According to an announcement from Mayor Tom Bates, the vendors will be able to renew their permits to operate in the new location for an additional two years.
Michael Koh, owner of Dojo Dog, Ann Vu, owner of Healthy Heavenly Foods, and Jack Huynh, owner of Kettle Corn Star, were forced to vacate their previous location near the intersection of Telegraph and Bancroft in December, when construction started.
Koh spoke at the Telegraph Avenue brainstorming convened by the mayor last month, and local councilmember Kriss Worthington had asked the city manager to assist in the relocation. Worthington's referral is on the City Council's action agenda for tonight's meeting.
Worthington's referral points out that, although the Lower Sproul project construction has been planned for years, the food vendors were given just two days' notice to vacate their locations. … Continue reading »
Shop Talk: The ins and outs of Berkeley businesses
GETTING MEATY Green Papaya, the Thai vegetarian restaurant at 2016 Shattuck in downtown, is switching it up. It's changing its name to Thanu's Kitchen and is adding meat to the menu. A notice on the door says that the new spot will open soon. "Although we're changing things up a bit here, we will still offer vegetarians our selective menu and, no worries, our utilities such as pots, pans, and ingredients for vegetarian will most definitely be separated from non-vegetarian," write the owners, who say the change is due to "a low volume of vegan/vegetarian consumers".
SPORTY OPENING Berkeleyans who are still missing Blakes, which closed its doors last year after 71 years, can now patronize Pappy's on Telegraph, which opened a couple of weeks ago in the old Blake's space at 2367 Telegraph Avenue. According to the East Bay Express, there is "a giant TV screen, plenty of sips, pitchers and noshes, and enough blue and gold to satisfy any Oski devotee". The name is a nod to former football coach Pappy Waldorf. … Continue reading »


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Jon and Kate Gosselin of TLC's docudrama Jon & Kate Plus 8, about their family life with two sets of multiples, may have trouble in paradise.
The couple appears to have serious marriage problems now that Jon has started spending increasing amounts of time away from home and partying with college girls, claims InTouchWeekly.com.
In a Feb. 6 incident, Jon was reportedly hanging out at Mimi's martini bar in Huntingdon, Penn. — easily three hours away from the new home he and Kate moved into with their children — when he met some girls from Juniata College who invited him to a house party.
"He walked in with two girls he met at Mimi's bar," a senior tells the magazine. "It was so cool."
Jon then proceeded to play beer pong and then follow the party with a nightcap at Memories Sports Bar & Grill, where he reportedly got drunker, flirted with the Juniata girls and told one, "We might be getting a divorce."
Star Magazine had earlier reported one witness' account:
"He was dirty dancing with several of them, making out, kissing them on their necks and mouths. I thought it was rather surprising for a father with his wife and so many kids at home to be acting like this. He was all over one girl, a long-haired blonde who's nearly 6 feet tall. He left with several of the girls, including her."
Check out pics of Jon's night of revelry that someone posted to Photobucket and a Livejournal pic of Jon with two girls at another bar near his home.
All the rumors have prompted Jon to issue the following statement through his rep:
"It is certainly hurtful for people to spread rumors and lies about us. It certainly makes me reluctant to live my life like the average person would. This has made it very clear that the simplest innocent gesture — such as taking a picture with a fan, can be taken out of context. As you can see on the show, I am not perfect, but I am a part of a loving family and couple."
Jon and Kate have often bickered on camera, part of the everyday activities on the show that includes family outings, movie nights and dentist visits. The couple even traveled to Hawaii to renew their wedding vows. The latest episodes documented their move into a $1.3 million mansion and the purchase of two German Shepherd puppies.
Their children include 8-year-old twins Cara and Mady and 4-year-old sextuplets Alexis, Hannah, Aaden, Collin, Leah and Joel. The children were the result of fertility treatments.
The elder Gosselins have come under attack for exploiting their children and the blog Gosselins Without Pity offers rather snarky recaps of the show and a forum for Gosselin critics.
Check out Jon & Kate Plus 8 photos from the show and of their Hawaii trip to renew their wedding vows.
What do you think? Has this been a long time in coming or is it a surprise? Can Jon and Kate work it out?
PICS: 'Jon & Kate Plus 8'
'Jon & Kate Plus 8' finale doesn't address divorce rumors
TV Ratings: 'Jon & Kate' plus 10 million
More 'Jon & Kate Plus 8' on the way
'Jon & Kate Plus 8' fifth season confirmed, but is it wise?
'Jon & Kate Plus 8': Jon 'never cheated'
'Jon & Kate Plus 8' recaps
The 'Other Woman' stories:
'Jon & Kate Plus 8's' Jon Gosselin admits to 'poor judgment,' not cheating
'Jon & Kate Plus 8's' Jon Gosselin seen with mystery woman
Jon Gosselin is a faithful husband and good dad, say friends
'Jon & Kate Plus 8's' mystery woman speaks up"
'Jon & Kate Plus 8' dad's 'gross' affair confirmed by woman's brother
VIDEO: 'Jon & Kate Plus 8' dad supposedly sneaking out the morning after
'Jon & Kate Plus 8' mom Kate Gosselin blames Jon for 'tension'
VIDEO: 'Jon & Kate Plus 8' mom 'hesitant' to believe tabloids
VIDEO: 'Jon & Kate Plus 8's' Kate Gosselin tells Larry King kids are 'unaware' of the rumors
'Jon & Kate Plus 8' production runs late
Other marital woes and Kate drama:
POLL: Kate Gosselin's hairstyle: A 'do or a don't?
Kate Gosselin accused of cheating: Jon & Kate Plus 10?
'Jon & Kate' split 8? Is divorce imminent?
Kate Gosselin's brother: 'Jon & Kate' in a sham marriage
'Jon & Kate's' Kate Gosselin: Worst. Boss. Ever.
'Jon & Kate' roundup: Jon's $5 allowance, J.Lo and the kids


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Today, I had dinner with my family in celebration of my 19th Birthday. I've been hinting that I need a new laptop for months now and I was sure my family had bought me one. I have got a pair of slipper socks. FML
by Unloved. / 09/15/2009 at 6:09am / New Zealand (Wellington) / Miscellaneous
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I listened to a narrated audiobook version of this novel. Read by Anne Flosnik.
Hero: Edward Ailsbury, the new Earl of Heyward, knows he must marry. As a spare, now heir, he knows the importance of preserving the family lineage. The candidate he has in mind is his family friend and favorite bluestocking, Eunice Goddard. A wife should be a friend, someone intelligent that one can converse with, and a lady unblemished by scandal or wild behavior, but when the lady refuses him, he's flummoxed. What now? Well, his family wants him to court Angeline Dudley and so he does. He's flummoxed again when he realizes that the scandalous Miss at the inn is none other than she!
Heroine: Angeline Dudley is preparing for her first Season. She's determined to catch herself a simple steady gentleman, a man completely opposite her rakish brothers and father (now passed away). A potentially scandalous incident at a public inn reveals to her just such a man and it's instant attraction for her. All she wants is his good opinion and his love, but it seems to be the thing he's determined to hold back. She suspects his interested lie elsewhere and does all in her power to bring them together, for his sake and Eunice's sake (who becomes her friend).
Review: I really liked the pairing of a stuffy, circumspect, and introverted hero (who doesn't think he is and takes offense when he's called on it) with a bubbly, impulsive, and extroverted heroine (who rambles and says things to upset the hero… like calling him a dry stick 😀 lol).
He's extremely dignified and extends politeness and courtesy as a shield. She prattles to fill uncomfortable silences and makes jokes at her expense to hide her insecurity. Angeline feels she doesn't deserve him and her innocent behavior appears to be reckless behavior.
I also thought it was incredibly sweet that the heroine put the hero's desire so far above her own she tried to orchestrate opportunities for him to meet Eunice in hopes he'd propose to her. There were lots of great quotes in the story, my favorite is below.
Favorite Scenes: Their first meeting at the inn, and Edward's first proposal to Angeline.
Favorite Quote:
In a few short minutes he had shown himself to be her ideal of manhood. Of gentlemanhood. He seemed perfectly content and comfortable with his ordinariness. He seemed not to feel the need to posture and prove his masculinity at every turn preferably with his fists… He was in fact, more than ordinary. He was an extraordinary man.
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Commercial and Contract Litigation
Whether you need a contract reviewed or drafted for an important sale or purchase, we can help ensure that there are no loose ends. And, if a transaction is going or has gone bad, we will provide you experienced, effective representation through negotiation, Alternative Dispute Resolution (ADR) or trial. Whether your issues arise in a Uniform Commercial Code (UCC) setting or a traditional contract law setting, we can help your business achieve the best possible outcome.


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Qandery Mountain Conditions?
Colorado 14er peak questions, condition requests and other info. 14er Trip Reports, Condition Reports
- Fisching
- Posts: 479
- Joined: Sat Oct 10, 2009 1:26 pm
- Location: Sao Paulo, Brazil
Re: Qandery Mountain Conditions?
Peter Aitchison on the risks of rock climbing and mountaineering: "That's life, isn't it? We think the challenge and satisfaction you get from doing this is worth the risks."
"Respect the mountain. Train hard. Hope you can sneak up when it isn't looking."
"The mind is always worried about consequences, but the heart knows no fear. The heart just does what it wants."
"Respect the mountain. Train hard. Hope you can sneak up when it isn't looking."
"The mind is always worried about consequences, but the heart knows no fear. The heart just does what it wants."
- rijaca
- Posts: 2689
- Joined: Sat Jul 08, 2006 7:36 pm
- Location: Minglewood
Re: Qandery Mountain Conditions?
The requested user does not exist.
"Well a couple shots of whiskey, women `round here start looking good"
- AckMonster
- Posts: 15
- Joined: Fri Jan 25, 2013 2:57 pm
Re: Qandery Mountain Conditions?
Chucks? As if. Spatula if you haven't figured out the mountain hierarchy yet it is all about looking good (especially on those winter climbs). The most important things in mountaineering are 1) FASHION 2) accomplishing your goal at any cost and 3) safety. Chucks may get you to the top but you need to summit in style. May I suggest some more fetching mountaineering footwear: http://www.zappos.com/ugg-classic-short-bomber-bomber-jacket-chestnut
- Taillon75
- Posts: 209
- Joined: Wed Dec 30, 2009 1:23 pm
- Location: Westminster, CO
Re: Qandery Mountain Conditions?
Rent Vertical Limit, Cliffhanger and K2! That's all you need to know about climbing in Colorado.
Catchy saying from someone famous.
- Jesse M
- Posts: 633
- Joined: Mon Jul 18, 2011 8:14 am
Re: Qandery Mountain Conditions?
I am fairly new to ForTEENers.com
Oh I get it, I think?
Well good luck on your Qandery trip, post a TR because I have never heard of this mountain.
- Nelson
- Posts: 397
- Joined: Mon Aug 25, 2008 1:52 pm
Re: Qandery Mountain Conditions?
Qandery is just south of Beckenridge.
Am I the only guy that doesn't know what "Chucks" are?
Am I the only guy that doesn't know what "Chucks" are?
- Scott P
- Posts: 6426
- Joined: Wed May 04, 2005 10:46 am
- Location: Craig
Re: Qandery Mountain Conditions?
Am I the only guy that doesn't know what "Chucks" are?
I didn't know either. Maybe these?
I'm slow and fat. Unfortunately, those are my good qualities.
- edhaman
- Posts: 491
- Joined: Sat Aug 21, 2010 11:10 am
- Location: Lakewood, CO
Re: Qandery Mountain Conditions?
I usually pass up the Chucks for the Bills, Freds, or Marys.
- colokeith
- Posts: 485
- Joined: Mon Jan 03, 2011 1:03 pm
- Location: Castle Rock, CO
Re: Qandery Mountain Conditions?
Nelson wrote:Qandery is just south of Beckenridge.
Am I the only guy that doesn't know what "Chucks" are?
They are flat bottom converse sneakers. I have seen them primarily in weightlifting
To climb is to push yourself in a way you might not normally imagine is possible. If your stamina, skill, and luck are sound you will get to stand on top. ... I realized that with climbing, I'd found something that nourished my soul and could forge me into a better version myself - Jim Davidson
- MonGoose
- Posts: 1051
- Joined: Fri Aug 14, 2009 2:53 pm
- Location: Denver, CO
- Massholeo
- Posts: 24
- Joined: Fri Jun 22, 2012 7:17 am
Re: Qandery Mountain Conditions?
Converse Chuck Taylor All-Stars? I'm 33 and now I feel old, seeing as some have not seen or heard of these canvass wonders for the feet. Sad day, sad day. Grab a photo of any hoops team from the 20's through 1970's and more than likely they'll be sporting a pair. An icon of American athletic apparel.... sure. Footwear for hiking....may as well borrow my Sanuks.


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Innovative nonprofit agency is seeking an organized, hands-on, energetic individual to teach a classroom of 20 young children in our daycare center located in a family homeless shelter. Qualified candidates will have experience working with high-needs families and young children, and be able to thoughtfully and creatively address the needs of the children and families we serve.
This position is an excellent opportunity for an enthusiastic child care and education professional to work in a child care program that meets the needs of a high-risk, vulnerable population.
The Teacher will collaborate with the program's director on daily lesson planning and curriculum development. The ideal candidate will demonstrate a passion for active engagement in classroom activities as well as an ability to work well with supervisory and support staff.
• Collaborate with director on curriculum development and daily lesson planning
• Actively create and maintain a child-oriented and literacy-focused atmosphere
• Ensure developmentally appropriate educational, physical, and hygienic care of the children
• Interact closely with and supervise children at all times
• Ensure respectful interactions with children, parents and staff
• Provide a balance of activities to meet the children's needs
Bachelor's degree in Early Childhood Education and one year experience or BA/BS and 5 years of experience teaching pre-school
NYS certified preferred
How to apply
To apply, please email cover letter and resume to Alex Rogutsky at email@example.com. Please include "Teacher" in the subject line. Phone calls will not be accepted.
Alex Rogutsky


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Armed Defense & CCW Classes for Civilians!
Please "Like Us" on Facebook to receive class and info updates.
"Safety & Defense for Landlords and Real Estate Professionals" Wed. Dec 7 at 5 pm at McDowell's Desert Supply store's New Location – 4350 Hwy 95 Ft. Mohave, 1/2 mile north of Camp Mohave Rd. Jamie will discuss how real estate professionals can protect themselves while showing property, collecting rent or making repairs – open to everyone, but directed toward landlords, realtors and repairmen at our FREE monthly self defense seminar.
LEOSA – HR218 Law Enforcement CCW: We are an authorized qualification exam center for LE officers certified under the Federal LEOSA – HR218 CCW permit.
Small Group and Private Classes: If you are visiting for only a few days or you can't attend a scheduled class we offer private classes for 1-3 or more students to fit your schedule. Our goal is to help you gain the training, skills and knowledge you need.
NRA Instructor Marathon! Coming in March 2017! Take one or ALL the NRA classes from Basic through Instructor and learn to teach others!
StarFire Tactical is the only dedicated NRA, civilian defense and security officer training facility serving Fort Mohave, Bullhead City and all Mohave County, AZ with range facilities at the Tri-State Shooting Park. We own our facility and work with our affiliated local gun stores to bring quality training to the Tri-State region. We offer Concealed Weapon Permit classes for Arizona and Utah, and teach StarFire propitiatory and NRA armed self defense and firearm safety classes for pistol, rifle and shotgun. We are the regional Arizona Security Officer and LEOSA Qualification Center.
We don't just teach you to shoot – you learn to "Run your Gun!" We teach the safety fundamentals, legal knowledge, operational skills, and mature, responsible attitude to safely, effectively, confidently, competently and legally protect and defend yourself and those you are responsible for!
Class dates and times subject to change based upon enrollment. Please call with any questions prior to enrolling or paying online.
Phone: 702-496-0165.
Course Overview
These are the classes you will remember for the rest of your life! Our dynamic instruction is intense, in-depth and informative! Safety is fundamental and stressed at all times!
CONCEALED WEAPON PERMIT CLASSES: This is the "must have" legal knowledge course for anyone contemplating carrying a weapon for defense. We teach the "Legal Aspects of Concealed Carry" for Arizona and Utah. Our certificates are also accepted by Florida, Virginia, Colorado and several other states as proof of training.
ARMED DEFENSE FOR CIVILIANS: We teach a three course series of Basic, Intermediate and Advanced armed self defense. No fancy course titles – no "drill sergeant" mentality – just the solid foundational skill training you need to survive and prevail in a defensive incident. We also offer half-day specialty clinics such as "road rage," "red-dot," and "night fire!"
ARIZONA SECURITY GUARD CLASSES: We are Northern Arizona's only Armed Security Guard training facility with classes in armed and unarmed security and annual or bi-annual required re-certifications. We also offer Security Shotgun and Basic Patrol Rifle.
PRIVATE AND SMALL GROUP CLASSES: We offer private instruction and semi-private classes to fit your schedule. Please call to discuss your specific needs.
ARMORER / GUN REPAIR CLASSES: Starting in September 2015 we will be offering Basic Armorer classes for Glock, 1911 and AR15. These affordable 1/2 day classes will teach you how to completely detail strip your listed firearms to the frame for cleaning, minor repairs or basic upgrades. Please watch our calendar for upcoming class dates!
PERSONAL SAFETY SEMINARS FOR RETAIL AND REAL ESTATE: We offer 1-2 hour seminars tailored to Real Estate Professionals and Landlords, and Retail employees. This is "must have" knowledge for these high risk businesses. Topics include risk recognition, confrontation avoidance, risks and liabilities. Legal aspects of self defense. Safe zones and ballistic shields. Unarmed defensive response and escape plans. Active shooter or employment violence mitigation. Pros and cons of armed defense and training options. Aftermath management and more.
LEGAL ASPECTS OF ARMED ENGAGEMENT SEMINAR: This is a 2 hour seminar designed to introduce the legal aspects of self defense and how to protect yourself from arrest and lawsuits. Topics include pertinent laws and their application, rules of engagement and evidence, prior knowledge, justification, witness and post incident scene management, what to say to police and when to shut up!
The classes listed above are not NRA approved courses.
NRA CERTIFIED FIREARM SAFETY AND DEFENSE COURSES: We offer NRA firearm safety and defense courses, to include Basic Pistol "Phase II," Basic Rifle, Basic Shotgun, Personal Protection Inside and Outside the Home and Certified Range Safety Officer. These classes are designed to provide the student with the skills, knowledge and attitude for safe recreational or defensive shooting as taught exactly to the NRA national curriculum standards. These courses are recommended for students seeking NRA training credentials.
NRA CERTIFIED INSTRUCTOR TRAINING COURSES: We offer Basic Instructor Training (BIT) Basic Pistol, Rifle, Shotgun Instructor, Personal Protection Inside and Outside the Home and Chief Range Safety Officer. These classes are designed to provide the Instructor Candidate with the skills, knowledge and attitude to TEACH safe recreational or defensive shooting as taught exactly to the NRA national curriculum standards. These courses are recommended for students seeking NRA Instructor credentials. Instructor Candidates are expected to know how to safely handle firearms and shoot accurately.
Mission Statement:
The mission of StarFire Tactical is to teach the fundamental skills, knowledge and attitude for the safe and responsible use of firearms by civilians for self defense, recreational or sporting purposes, and to instill the confidence and competence required to survive and prevail before, during and after a deadly force incident.


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Pressure is a fact of life when you play in the NFL.
It's everywhere.
The ability to perform under this enormous mental strain separates the All-Pros from the wannabes.
When a team puts a player in a situation where if they falter, the season crumbles, it makes the pressure even more intense.
With that in mind, here's a look at eight players who are facing that kind of stress as training camp begins.
All of them are being counted on to step up and be a catalyst for their team's success.
Seven are on the offensive side of the ball and three of the eight are rookies. Feel free to comment with your own list or differences of opinion.