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Favorite Glee Quotes
Did you know that dolphins are just gay sharks?Brittany
Your hair looks like a briar patch. I keep expecting racist, animated Disney characters to pop up and start singing about living on the bayou.Sue
I will no longer be carrying around photo ID. Know why? People should know who I am.Sue
I'm so depressed I've worn the same outfit twice this week.Kurt
I'm pretty sure my cat is reading my diary.Brittany
Rachel: Break a leg.
Finn: I love you.
[God] makes me gay and then makes His followers go around saying it's a choice, as if I'd choose to be mocked every day of my life.Kurt
I want Channing Tatum to stop being in stuff.Mike
When I heard Sandy wanted to write himself into a scene as Queen Cleopatra, I was aroused. And then furious.Sue
Rachel manages to dress like a grandmother and a toddler at the same time.Kurt
[to the panel] Okay. I'm just gonna come out and say it. This is a singing competition. I don't know how those deaf kids got in. They weren't singing, they were like honking and everyone was crying and I was like, "Get off the stage. You're terrible and you're making me super uncomfortable."Candace
My mom won't even let me watch Twilight. She says she thinks Kristen Stewart seems like a bitch.Tina


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Add the Missing Link to your animal's regular food according to its weight. As with any high fiber product, start with small amounts and gradually increase to the recommended level over the course of a week or two.
Some animals may benefit even more if their Missing Link intake is doubled for the first 90 days following the adjustment period.
The daily intake can be divided into two or more servings if desired.
Daily Intake:
Up to 25 lbs - 1 teaspoon
25 to 50 lbs - 2 teaspoons
50 to 75 lbs - 3 teaspoons
75 to 100 lbs - 4 teaspoons
Over 100 lbs - 5 teaspoons

subset: commoncrawl


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Showing irreducibility is not enough, you must also prove that the only units in your domain are 1 and -1.
Consider the integral domain .
Show that and have no common factors in except for and .
I can show that both and are irreducible. However, is there another way to prove that and are the only common factors?


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Let MLK , Jr. Day be Equality Day
As we once again celebrate a great orator, leader and inspirational figure, we must also realize there's a correct and equal way to celebrate Martin Luther King, Jr.
No other holiday is named for just one person. President's Day is for all presidents, Memorial Day is for all those who died in wars, Mother's Day is for all mothers and Veterans Day is for all veterans. All of these holidays are for those regardless of religion, sex or race. (Columbus Day should be renamed Founders Day or Discovery Day and Christmas is a religious holiday).
The struggle for color blindness and equal opportunity began many generations before and continues generations after MLK.
Cesar Chavez (who by the way was against illegals taking jobs from the legal farm workers whom he represented,) W. E. B. Du Bois, the white abolitionists, Frederick Douglass, Rosa Parks, Lyndon B. Johnson (without whom much legislation would not have passed); the white college students and citizens who marched with the protestors — all these figures played a prominent role in the struggle.
As such, I believe MLK would be ashamed and embarrassed that his name and his name alone is celebrated as the starting point for equal opportunity rights.
Perhaps we should rename MLK Day to Color Blindness Day, Equality Day or Equal Opportunity Rights Day so as to be inclusive of all those who fought and struggled and who continue to do so today and tomorrow.
Maybe then there would be fuller participation by those who feel MLK Day is not on equal footing with other recognized holidays.
I would love to see parades and speeches and writing contests about the presidents during February for President's Day as done so during MLK celebrations.
I would love to see students writing about the Constitution and extolling the wisdom of the Bill of Rights on Constitution Day in September.
Equal exposure.
Mike Coley
Fayetteville, Ga.


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Over the past year, restaurants have been plugging the holes in their operations to hang on to recession-weary customers, and according to the 2010 Leaky Bucket Study, they have begun to turn the tide.The overall industry "leak size," which measures the percentage of customers who say they're unlikely to return to a particular restaurant, fell from 36 percent in 2009 to 32 percent in 2010, erasing much of the jump from a 29-percent rate in 2008.But foodservice brands' work is far from over. ...
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Saints blow out the BucsAnd today, this Saints team played very, very well. But the Saints played on Sunday like they still care. This game has to be a huge disappointment to first-year Bucs coach Greg Schiano. And say this for the Saints: For everything that went wrong this yea… (more)Source: profootballtalk.com
Tom Jones' Two Cents: Tampa Bay Bucs vs. New Orleans SaintsBy Tom Jones, Times Staff Writer Sunday, December 16, 2012 Biggest decisionThe Bucs suddenly have a quarterback who can't hit water if he fell out of a boat. They couldn't run the ball Sunday. They scored zero points against what was, statistically, the…
Photo gallery: Saints 41, Bucs 0Images from the Bucs' loss to the New Orleans Saints.
Bucs' transition phase in full regression nowBy Gary Shelton, Times Sports Columnist Sunday, December 16, 2012 NEW ORLEANSI would hereby like to take back every compliment, especially the sincere ones.I want to apologize for every positive feeling I may have foolishly passed on to others.I wish to…
Brees throws 4 TDs; Saints shut out BucsDrew Brees passed for 307 yards and four touchdowns, and the New Orleans Saints recorded their first shutout since 1995 in a 41-0 victory over the Buccaneers on Sunday, virtually ending Tampa Bay's already slim playoff hopes.Source: ESPN.com


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ColbertBuschSC (D) @ColbertBuschSC
Politwoops no longer follows this account.RT @taycain: Congratulations to @ColbertBuschSC for securing the Democratic nomination for SC-1. Looking forward to the general election.
An archive of the public statements deleted by U.S. politicians. Explore the tweets they would prefer you couldn't see.
If you aren't an elected official or running for office and feel your account is being tracked by mistake then please contact us.


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Preventive Stress Management in Organizations, Second Edition
Supplementary Site
Welcome to the supplementary materials website for Preventive Stress Management, Second Edition. Because stress is systemic in nature for individuals and organizations alike, the diagnosis and measurement of stress cannot be accomplished with a simple or a single assessment or test. Therefore, we have identified a full range of measures and organized them into four broad categories. Each of the four documents includes a full set of references for the reader.
To really understand the experience and expression of stress in any individual or organization requires information and knowledge about the person or the system. These four documents describe a full range of assessments for undertaking that diagnostic journey.


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March 2009
Miriam Makeba
(3/4/1932 - 11/10/2008)
Miriam Makeba is, hands down, the most important female vocalist to emerge from South Africa. From her earliest years with the Manhattan Brothers in the 1950s, and for five decades thereafter, she has remained an important figure in the growth of African music.
As with most South African musicians, her life was not an easy one. The daughter of a mystical healer from the Xhosa tribe, she was imprisoned while still in her infancy. Many years later, while in her late 20s, her citizenship was revoked because of her outspoken views about apartheid. For the next three decades, she was forced to claim herself as a "citizen of the world." And yet, despite this and other struggles, she remained optimistic and forward thinking throughout her life.
I first met Miriam, known to so many as Mama Africa, at the Cape Town International Jazz Festival in 2006. We shared a meal and had some wonderful conversations, not just about music itself, but also about how great music can transcend ethnic and cultural boundaries and bring people of diverse backgrounds together.
We met several times after that, once at the French ambassador's residence in Pretoria, South Africa, as we discussed the idea of recording her classics with opera singer Barbara Hendricks and the Johannesburg Symphony Orchestra. Unfortunately, circumstances prevented the idea from materializing, but the fact that she would even entertain such a bold and innovative concept speaks to the broad and ambitious scope of her creative vision.
We did record Reflections, which was released in 2004. It was an opportunity to revisit some of her classic songs ("Pata Pata" and "The Click Song") with updated arrangements, as well as some Brazilian pieces and other new material. Clearly she would not allow herself to be limited to any particular style or be hampered by anyone's preconceptions.
I have always loved Miriam's approach to a song. She could sing effortlessly in several different languages, and she was a true storyteller in every one of them.
My only regret is that I didn't have more time and more opportunities to work with her. More than a great musician, she was an inspiration, not just to the people of her own nation, but to anyone anywhere who recognizes the transformational power of music.


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On Monday, 11 July from 3:00 p.m. through Wednesday, 13 July until 5:00 p.m. (USA Mountain Time), NSIDC data distribution, services, and Web site will be unavailable to accommodate a major upgrade to our data center. We apologize for any inconvenience this may cause you. Need to talk to us? You can always contact our friendly User Services Office at firstname.lastname@example.com or + 1 303.492.6199.
The Antarctic Glaciological Data Center (AGDC) at NSIDC archives and distributes Antarctic glaciological and cryospheric data collected by the U.S. Antarctic Program. From this Web site, you can access the data, the metadata, and the guide documentation for each data set as well as submit your data for archival, find related data sets, and access a collection of Antarctica photographs and images from the NSIDC archive.
Funding for this project is provided by the Division of Polar Programs, Antarctic Research, Glaciology Grant: NSF OPP ANT 0944763. AGDC is part of the U.S. Antarctic Data Consortium (ADC).


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Over 80% of all freshman entering CFAES receive a college scholarship. To maximize your opportunity to earn scholarships, Freshmen should complete the University Admissions Application by November 1st, our College Scholarship Application (to be eligible for college and departmental dollars), and the FAFSA (to qualify for scholarships that require documented financial aid) by February 15th. We also encourage looking to outside sources for scholarships and grants, whether they are large organizations or local companies.
Money Matters
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There are three types of financial aid available to those who qualify—scholarships, grants, and loans. Include us early in your planning, so we can help you navigate this process.
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66 posts tagged with intel.
Displaying 1 through 50 of 66. Subscribe:
Andrew S. Grove, Intel Chief Who Spurred Semiconductor Revolution, Dies
Andy Grove, former CEO and chairman of Intel, died yesterday at age 79.
Also at Ars Technica
Also at Ars Technica
Don't let it get you down, the singularity is as near as it's ever been.
Moore's law is dead, for real this time?
Antitrust Antitrust Antitrust Bring Back Antitrust
After 18 years in operation, after a federal law mandating that hospitals work to prevent needle-stick, and after two successful lawsuits resulting in BD paying more than $400 million for violating anti-monopoly statutes, Retractable Technologies made only $34 million in global sales last year. BD, with an inferior, more expensive product, sold $8.4 billion, the payouts to its competitor serving only as the cost of doing business. In 2000, the Centers for Disease Control estimated 380,000 needle-sticks at hospitals every year. Today, they estimate 385,000. "You turn on the TV and watch politicians talk about unleashing the power of the free market, that's absurd," Shaw says. "The American public is being denied a free market, being denied competition."We need a new antitrust for a new predatory era.
The Texas Instruments TMX 1795: the first, forgotten microprocessor
In the late 60's and early 70's, the technology and market were emerging to set the stage for production of monolithic, single-chip CPUs. In 1969, A terminal equipment manufacturer met with Intel to design a processor that was smaller and would generate less heat than the dozens of TTL chips they were using. The resulting design was the 8008, which is well known as the predecessor to the x86 line of processors that are ubiquitous in desktop PC's today. Less well known though, is that Texas Instruments came up with a competing design, and due to development delays at Intel, beat them to production by about nine months. [more inside]
insufficient context, scale, frequency or scope
"Instead, most current systems, almost without fail, do the opposite. Moderators responsible for content and complaints, regardless of gender, are making decisions based not just on the information they are reviewing, but on the way in which the information flows – linear, acontextual and isolated from other incidents. They are reliant, despite their best efforts, on technical systems that provide insufficient context, scale, frequency or scope. In addition, they lack specific training in trauma (their own or users) and in understanding gender-based violence. " -- "Silicon Valley sexism: why it matters that the internet is made by men, for men", by Soraya Chemaly, The New Statesman
Intel Includes
Intel Wants Diversity in the Workplace, Puts $300 Million Where Their Mouth Is - Also they have a cool stabby spider dress.
Intel Underestimates Error Bounds by 1.3 quintillion
Intel's manuals for their x86/x64 processor clearly state that the fsin instruction (calculating the trigonometric sin) has a maximum error, in round-to-nearest mode, of one unit in the last place. This is not true. It's not even close.
"The Techtopus": Much bigger than we realized
Mark Ames follows up on The Techtopus (previously) with a new report showing a much larger conspiracy than has been previously reported: [more inside]
The Silicon Valley cartel
Mark Ames on Silicon Valley's conspiracy to drive down workers' wages:
In early 2005, as demand for Silicon Valley engineers began booming, Apple's Steve Jobs sealed a secret and illegal pact with Google's Eric Schmidt to artificially push their workers wages lower by agreeing not to recruit each other's employees, sharing wage scale information, and punishing violators.... The secret wage-theft agreements between Apple, Google, Intel, Adobe, Intuit, and Pixar (now owned by Disney) are described in court papers obtained by PandoDaily as "an overarching conspiracy" in violation of the Sherman Antitrust Act and the Clayton Antitrust Act....[more inside]
"Nineteen months later, I feel safe answering"
"Why biotech whiz kid Jack Andraka is not on the Forbes 30 Under 30 list." Forbes science and medicine reporter Matthew Herper sends out Andraka's draft paper on his cancer diagnostic test to scientific experts, who find the results do not match the breathless excitement attracted by initial coverage, seen previously on MetaFilter and elsewhere. [more inside]
things that seemed like universal laws to people at the time
The Slow Winter [PDF]. A slightly true story about CPU design.
"A lesson about the success of Great Men"
gentle observer
Why People Really Love Technology: An Interview with Genevieve Bell The thing I love about Intel researcher Genevieve Bell is that she finds surprising things by looking at what's left out of the dominant narratives about technology. She finds data that's ignored because it didn't fit into the paradigm of, say, how people adopt technology. The dominant narrative is that young men determine the popularity of phones, computers, websites, and the like. But when Bell looked at the data, the story we told ourselves about how the world worked was not reflected in the numbers. That's why I wanted to talk to her about what gadgets people around the world might be using over the next decade. I figured she was someone who could look past the conventional wisdom and find the missing pieces of the future
Nokia MeeGon tarina
His name is Jack Andraka, and he loves science and engineering with every inch of his 15-year-old soul.
15 year old reinvents cancer detection, wins Intel International Science and Engineering Fair [more inside]
Surface to Air
Borrowing a name from another product, Microsoft today announced it's first ever hardware products running a mainstream version of Windows, and the first designed for Windows 8: The Microsoft Surface, in ARM and Intel flaovours. Hands on. Video highlighting the stand and covers.
I guess he had some kind of 'Total Recall' memory wipe in mind.
I've lost track of the many reasons that have been given for the [Apple OS X] switch to Intel, but this I know for sure: no one has ever reported that, for 18 months, Project Marklar existed only because a self-demoted engineer wanted his son Max to be able to live closer to Max's grandparents.
Anti-employee collusion by SF bay area tech companies
Google, Apple, Intel, Adobe, Disney, Pixar, Intuit and Lucasfilm are facing a lawsuit for their for their "no poaching" agreements (Bloomberg, TechCrunch). [more inside]
Things CPU architects need to think about
Things CPU architects need to think about. Bob Colwell gave this lecture in 2004, for the Stanford University Computer Systems Colloquium (EE380). Colwell was the chief architect of the Pentium Pro, Pentium II, Pentium III, and Pentium 4 processors. [About 90 minutes, Windows Media format] [more inside]
Competing with the MacBook Air
The PC industry is built around an idea of almost infinite variation: different Wi-Fi adaptors, different Ethernet chipsets, different GPUs, different USB3 controllers. This variety is then reflected in the systems available from manufacturers—and more importantly, it's reflected in the way the systems are actually built. … The big reason that HP wants to get out of the PC business is that it's simply not very profitable for HP—and that's true for all the major PC OEMs, Cupertino excepted. Cheap PCs are certainly important for making computing accessible, but they also mean that PC vendors have made themselves vulnerable: endless price cuts and a failure to emphasize the value of a quality product have cut revenues and slashed profitability. Desperate to compete on pricing and pricing alone, the mass-market PC OEMs have ended up cutting their own throats.Ars technica explains why the PC industry is having such a difficult time trying to build a competitor to the MacBook Air.
Science Fair Photos, 1942-2011
The Society for Science in the Public Interest photostream features photos of Westinghouse (now Intel) Science Talent Search winners from 1942 to the present. First place winner Ron Unz, later a failed California gubernatorial candidate and now publisher of The American Conservative. Nerds have always loved glowing liquids. Also van de Graaf generators. A guy made the finals with a sweeping robot. "Look! It's the future!" Ann Sieferle-Valencia won 7th place in 1997 with a an archeology project and is now the curator of the Tucson Museum of Art. George HW Bush digs science projects. So does Chuck Schumer. Tall finalist. Science! I just liked this one.
Intel Cougar Point has failed
As part of ongoing quality assurance, Intel Corporation has discovered a design issue in a recently released support chip, the Intel® 6 Series, code-named Cougar Point, and has implemented a silicon fix. Intel has identified the Northbridge chipset to the new Sandy Bridge processors to have an issue that will likely require the recall of all existing motherboards. Price tag for the recall is currently estimated to be $700 million. [more inside]
The Chase
The Chase through digital reality. It's an intel ad.
2010: The Year in Data Breaches
Wikileaks may have been the big news, but there were numerous other data breaches in 2010. [more inside]
HDCP master key is valid, encryption is now "only token protection"
High-bandwidth Digital Content Protection (HDCP) is currently the most common form of digital transmission protection for high definition digital multimedia, requiring an unbroken chain of licensed products for content to play back for TV systems and computers. A possible "master key" was posted online earlier this week, and created quite a stir around the potential of this leak or reverse engineering. Intel, who developed the initial specification, has confirmed the validity of the "master key", but instead of coming up with a new protection scheme, will use "legal remedies, particularly under the DMCA (Digital Millennium Copyright Act)." In essence, the threat of legal action, rather than cryptography, is [Intel and the media companies] real tool against unapproved uses of digital content. [more inside]
How to Make an American Job Before It's Too Late
How to Make an American Job Before It's Too Late. Andy Grove, from Intel, writes about America's lost manufacturing sector. [more inside]
"If you had unprecedented access to classified networks 14 hours a day 7 days a week for 8+ months, what would you do?"
Wired reports a US Intelligence Analyst has been arrested in connection with the "Collateral Murder" video released by Wikileaks. According to the article, SPC Bradley Manning was turned in by former hacker Adrian Lamo based on concerns about Manning's threat to leak an additional 260,000 classified embassy cables.
And I had hyperthreading, which was popular at the time...
Grandpa laces up his skates: How would a single core, 3.8 GHz Pentium 4 670 from 2005 compete against the latest offerings of AMD and Intel? How about a 2007 quad-core, the 2.4 GHz Core 2 Quad 6600? The Tech Report finds out in a Huge 14-way Roundout, including a price-performance evaluation (2nd perspective). For the release of AMD's new midrange DirectX 11 graphic card, the somewhat disappointing ATI Radeon HD 5830, they've done Something Similar, this time pitting older cards, including a Nvidia GeForce 7900 GTX from 2006, against the newcomer and today's top performers. (aggravation warning: hardware review sites love their multi-page layouts)
Trying to even out the false middle
Can a firefox extension extend rationality? Wherein intel labs attempt to add rationality to the web. Good freaking luck. [more inside]
OMG, Multi-Threading is Easier Than Networking [pdf, white paper about the multi-core future from Intel(R)]
Sienfeld wants you to buy Vista, Shatner wants you to buy a Vic 20
Et tu, Intel? Then fall, OLPC.
Wondering why OLPCNews.com disparages the OLPC project so much? Curious as to the site's apparent emphasis on bad news about the project? It could just be a coincidence. Or it could be because OLPCNews.com's chief contributor Wayan Vota works on a project that's partnered with Intel, a former OLPC partner turned competitor. Does Intel's back-stabbing extend beyond pre-sales and into public relations? [more inside]
To serve man (and woman)...
Hot, hot, XP on Mac action!
Windows XP booting on Apple hardware: confirmed. The $14000 contest to get Windows XP to boot on the new Intel hardware from Apple is over as of today. While considerable work in the realm of device drivers needs to be done, (and the rumored method may violate the Windows EULA) much of the hardware is straight Wintel. Considering that the MacBook Pro and Intel-based iMac (not currently working) both pack ATI Radeon X1600s, serious PC gaming on Apple hardware via dual-booting may finally be in the realm of possibility. [Via: slashdot, engadget]
Well I've got this guitar and I've learned how to make it chat
The Intel-Fender Concept Telecaster Guitar, or Intelecaster, is exactly what you think.
US plans to 'fight the net' revealed
US plans to 'fight the net' revealed "Information intended for foreign audiences, including public diplomacy and Psyops, is increasingly consumed by our domestic audience," it reads. "Psyops messages will often be replayed by the news media for much larger audiences, including the American public," it goes on.
Able Danger WP Series
The Secret History of Able Danger The WP may have have the goods on Able Danger. The Pentagon and Intel officials are mum on the data mining project because it could have been illegal.
Mac OS X Intel "Hacked"
Well it's happened the developer release of Mac OS X Intel x86 has been "hacked" to run on a PC Laptop. Here's the video torrent. (via)
Will Intel buy Apple?
The announcement that Apple was moving to Intel hardware was the first move in Intel's take-over of Apple, according to Robert Cringely, giving Intel a platform to compete head-to-head with Microsoft. "This scenario works well for everyone except Microsoft. If Intel was able to own the Mac OS and make it available to all the OEMs, it could break the back of Microsoft. And Apple/Intel could easily extend this to the consumer electronics world. How much would it cost Intel to buy Apple? Not much." More.
Human sacrifice, dogs and cats living together - mass hysteria.
Well, it's an old rumor, but many sources (including the NYT, WSJ, Wired, and many rumor sites) are reporting that Steve Jobs will be announcing a switch to Intel at the WWDC tomorrow. The WSJ claims Apple will be switching to x86 processors, while others speculate Intel will simply be manufacturing PPC chips, or only processors for a tablet PC. If the rumors are true, and it seems like they are, what of the Intel DRM recently announced? Are we destined to have DRM hardwired into our computers no matter where we turn? Curiously, the major rumor site has remained mum on the matter. Your best bet to follow the drama will probably be MacRumors, who will be providing live updates from Steve-o's keynote tomorrow.
All your content are belong to us
Think you're in full control of your computer? Think again. Intel has just quietly added one of the necessary components of Microsoft's (and the TCG/TCPA's) DRM technology, Palladium, to the PC platform. Some say this is a move against rampant Chinese software piracy, others think it's a power grab by the content producers. Left unchecked, content and software producers will have the final say in how you use your computer, fair use be damned.
build your own datacenter
The Intel IT Manager Game lets you manage an IT department (flash, reg. required, you don't have to enter a valid e-mail address). Here is another attempt (click "Simulation" at the top). For those who rather calculate than point-and-click, try the Ipas TCO simulation. [via Flex-MX Blog]
Dvorak: I'm smoking crack
Apple to switch to Intel processors, at least according to John Dvorak in a brief article over at PC Magazine. No mention in the article of the massive amount of effort required to re-write every piece of mac-compatible software for x86 architecture, or the unlikeliness of developers to be willing to do so having just optimized for OSX, but then, this piece seems to be mostly just bold, unsupported predictions.
E-mail is trespass?
E-mail is trespass? A disgruntled employee's emails to his former co-workers are a legally actionable form of 'trespass to chattels', says Intel. Have you ever trespassed to chattels? Should you fined or even jailed for it? 3 lower courts in Claifornia have said 'yes' to all or part of that last question. (linked to in a thread today, but it deserves it's own).
Has anyone read "Swimming Across" by Andy Grove?
Has anyone read "Swimming Across" by Andy Grove? It appears to be pretty far from the traditional "look-at-me, revel in my vision, I'm an uber-CEO," self-promotional book; he never even gets into his Intel career, apparently. Instead it's an account of Grove's childhood in Hitler and Stalin's Hungary and the story of how he came to America. The book has been getting great reviews, from people as diverse as Tom Brokaw, Elie Wiesel and Monica Seles. Still, the cynic in me says that no matter how dramatic the tale, when you're a Fotune 500 CEO, you always have other motives. Perhaps I'm just too cynical. So again, has anyone read it? What did you think?
Intel Likes the Napster Way (Wired Article).
Intel Likes the Napster Way (Wired Article). So, we've had Napster, and its counterparts, and we've had all sorts of cheerleading for P2P. P2P has taken off in a big way in the way of IMing, and in a smaller way via projects like SETI@home. Now there's a major corp using it for internal practices in a big way. Are any of you seeing any interesting uses of P2P where you work?
Where Apple goeth, the industry will follow . . .
Where Apple goeth, the industry will follow . . . eventually. "Intel is finally inciting the death of the floppy drive and is calling on PC manufacturers big and small to stop supplying the once-capacious 1.44MB removable drive in the latter half of 2002." I remember the first 3.5 inchers (weren't they 400k) with my first Mac in '84. Yet another era passes.
The last computer you'll ever own.
The last computer you'll ever own. With the entertainment industry pushing electronics manufacturers towards closed, proprietary hardware, how soon will we be limited to strictly "renting" media, serives, etc.?
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Welcome to the Abercorn Seventh-day Adventist Church website. We are a Seventh-day Adventist Church located in Abercorn, Quebec.
We invite you to discover our church. On these pages you'll find information about our worship, beliefs, directions to our church, and much more. Be sure to check our calendar for information on upcoming events at our church.
We are part of a worldwide Christian faith community preparing for the return of Jesus Christ. We encourage you to find out what God is doing at our church by attending our weekly worship, study groups, and social activities.
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The Bible Says


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creative garden design
inspired by nature
Jackson Hole is an environment unique unto itself. People travel from miles around to take in it's vast beauty and breathtaking peaks. A New Leaf recognizes this special place in our world and strives to become a steward in its honor. We believe in intentional design with nature in mind. We specialize in creating spaces unique to each individual site, collaborating with you to manifest a garden full of inspiration, pride and visual beauty. With over 10 years of gardening experience, we can assist you with all aspects of your natural world, from design to installation to weekly maintenance.
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Collective joy
May 12, 2011 —
GRAHAMSVILLE, NY — In his latest book entitled, "Our Choice: A Chance to Solve The Global Climate Crisis," Al Gore reflects on an ancient proverb, "If you want to go fast, go alone. If you want to go far, go together."
Collaborating to achieve a common objective makes great sense in a world where complex problems require the participation of many, not a few, if they are to be solved. Sports are a microcosm of the human experience and, as such, teamwork is a quintessential element thereof. That said, although track and field is a team endeavor, the scoring at meets is heavily weighted by individual performances, with the exception of relay races that involve a quartet of runners.
But each year at the Tri-Valley Relays, collective efforts take on an added allure as the jumping and throwing events feature pairs of athletes whose combined distances are used for scoring. The meet still features a few individual endeavors, such as the 100, the steeplechase, the pentathlon and the 1500/1600 runs. But everything else reinforces Gore's reference about going far as a product of going together.
To that end, several combined efforts are worthy of mention in the meet won by Ellenville's boys and Rondout Valley's girls. Locally, Tri-Valley's girls were second out of 14 teams, while Liberty was sixth. In the boys' realm, Tri-Valley finished fourth overall. Eldred was sixth. Sullivan West was not on hand for this meet, nor were the boys from Monticello.
Among the first-place collective girl finishes for Tri-Valley were: the freshman/sophomore sprint medley relay (4:40.8), f/s 400 relay (55.3), 1200 intermediate hurdle relay (3:51.2), varsity shot put relay (65-3 ¾), f/s shot put relay (58-8 ½), javelin relay (169-2) and the hammer relay (145-9). Liberty's girls, famous for their fiery speed, prevailed in the varsity 800 relay (1:51) and the varsity 400 relay (51.4). Individual efforts by Liberty's Jessica Dunnigan in the 100 (12.5) and Tri-Valley's Caroline Bertholf in the 2000 steeplechase (8:13.1) figured into the day's outcome as well. Dunnigan was named the meet's Outstanding Female Track Athlete for her role in the winning 400 and 800 relays. Tri-Valley's Heidi Furman was named the meet's Outstanding Female Field Athlete for her role in the winning shot put and javelin relays. She helped her team win a silver medal in the hammer throw relay, an event T-V also took first in.


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Water Pressure Problems Plague Firefighters At Duquesne Apartment Building BlazeEmergency crews were called to the scene of a two-alarm apartment fire in Duquesne.
Duquesne Community Mourns 16-Year-Old Killed In ShootingA community is in mourning as the investigation continues into a shooting that claimed the life of a 16-year-old and left three of his family members wounded at an apartment building on Saturday evening in Duquesne.
Teen Dead, 3 Others Wounded In Duquesne ShootingA teenager is dead and three of his family members were wounded when a barrage of gunfire broke out at an apartment building in the City of Duquesne Saturday evening.
Fire Damages Apartment Complex In DuquesneThe Allegheny County fire marshal is investigating following an early morning fire at an apartment complex in Duquesne.


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This online tracking tool lets you track what you eat to manage your diabetes and prevent the onset of complications. Explore nearly 5,000 foods and find recipes and healthy alternatives to improve your meals. En español
American Diabetes Association (ADA)
This tip sheet helps Hispanics/Latinos at risk for type 2 diabetes move more and eat less to reduce their risk. En español
National Diabetes Education Program (NDEP)
This booklet and website, designed for Latino families, provides information on how to stay healthy and prevent diabetes problems, especially heart disease.
National Heart, Lung, and Blood Institute (NHLBI)
This comprehensive kit includes reproducible patient education handouts on 29 topics related to cardiometabolic risk reduction, prediabetes, diabetes, and CVD. En español
American Diabetes Association (ADA)
This list of self-management support training materials provides health care professionals with strategies and patient tools to help patients adopt healthy behaviors.
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This three-booklet package helps you assess your risk for developing diabetes and implement a program to prevent or delay the onset of the disease. Use the activity tracker and fat and calorie counter to help track your progress. En español
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This comprehensive guide will help you control your diabetes by keeping a balance between what you eat, your physical activity, and your medication. It will also help you take important steps to prevent diabetes-related health problems. En español
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This inspirational booklet, written by Dr. Steven Covey, features seven habits that can help you with diabetes management. Learn to become more effective in managing your diabetes on your own, with your medical team, and with your family and friends.
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The National Diabetes Prevention Program lifestyle training curriculum is based on the Diabetes Prevention Program (DPP). The lifestyle program is divided into two components: Core Curriculum & Post-Core Curriculum.
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This toolkit provides materials to begin a community outreach program with African Americans and Hispanics/Latinos at risk for type 2 diabetes, reinforcing the message that type 2 diabetes can be delayed or prevented. CME credit available. En español
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Emu (puppet)
The logo for the new series of Emu.
|Created by
|Rod Hull
|Portrayed by
|Toby Hull
Emu is a puppet emu given to British entertainer Rod Hull in the 1960s while he was presenting a children's breakfast television programme in Australia. Hull adopted the mute puppet for his cabaret act, and took it with him to the United Kingdom when he returned in 1970.[1] The character was given a mischievous and sometimes aggressive onstage persona, attacking celebrity guests (and Hull himself) for comic effect. Hull and Emu also appeared on several episodes of The Hudson Brothers' comedy show in the United States.[citation needed]
Hull's son Toby Hull returned Emu to television on CITV in October 2007.[1] The new persona of Emu vocalises, allowing viewers to understand what the character is thinking. Emu is controlled by an unseen puppeteer, allowing his handler Toby to move around independently. The series is set in a modern apartment block where no pets are allowed, so Emu has to beware of his next door neighbour, Sophie.[2]
Emu's other neighbours are two young cousins, Charlie and Dani, who help Emu outwit Sophie, who wants to use Emu as a quick way to make money. While Toby is oblivious to Sophie's scheming, Charlie, Dani, and Emu know her true colours. Toby also has to keep Emu a secret from Ken Cole, a grumpy security guard.
In June 2009, it was announced that CITV had ordered a second series of the show, set in a craft cafe,[3] Emu being pitted against the health inspector Leo. The first episodes were broadcast on September 13 on ITV1.
- ^ a b "Emu set for television comeback". BBC News. 2006-06-08. Retrieved 2006-06-08.
- ^ "The beak is back: Emu returns to CITV". The Stage. Retrieved 2009-04-11.
- ^ Parker, Robin. "CITV orders more Emu | News | Broadcast". Broadcastnow.co.uk. Retrieved 2009-06-03.
|This puppet-related article is a stub. You can help Wikipedia by expanding it.


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Happy Valentine's Day from the PCH Blog Team!
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Roses are red, Violets are blue, Sugar is sweet, But not as sweet as you! Blog readers, oh blog readers, You're simply the best, Better than chocolate and flowers, Better than all the rest! Thank you for the love, The comments and cheer, Thank you for believing, Year, after year! We wish you the happiest [read more…]


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van Sighem, Ard Ia; van de Wiel, Mark Ab; Ghani, Azra Cc; Jambroes, Mariëlled; Reiss, Petere; Gyssens, Inge Cf; Brinkman, Keesg; Lange, Joep MAe; de Wolf, Franka,c; on behalf of the ATHENA cohort study group
From the aHIV Monitoring Foundation, Academic Medical Centre of the University of Amsterdam, Amsterdam, the bDepartment of Mathematics and Computer Science, Eindhoven University of Technology, Eindhoven, The Netherlands, the cDepartment of Infectious Disease Epidemiology, Imperial College School of Medicine, London, UK, dNational Association for Community Health Services, Utrecht, the eDepartment of Internal Medicine, Division of Infectious Diseases, Tropical Medicine and AIDS, and the National AIDS Therapy Evaluation Centre, Academic Medical Centre of the University of Amsterdam, Amsterdam, the fDepartment of Medical Microbiology and Infectious Diseases and Department of Internal Medicine, Erasmus University Medical Centre, Rotterdam and the gDepartment of Internal Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands.
See also p. 2259
Correspondence to Ard van Sighem, HIV Monitoring Foundation, Academic Medical Centre, University of Amsterdam, Meibergdreef 9, 1105 AZ, Amsterdam, The Netherlands. Tel: +31205666781; fax: +31205669189; email: firstname.lastname@example.com
Received: 8 August 2002; revised: 10 March 2003; accepted: 19 March 2003.
Objectives: To examine survival and progression to AIDS among HIV-infected patients after starting highly active antiretroviral therapy (HAART).
Methods: The study population consisted of 3724 patients from the ATHENA observational cohort who initiated HAART. We considered progression to either an AIDS-defining disease or death, distinguishing HIV-related and non-related (including therapy-related) deaths. A time-dependent multivariate hazards model was fitted to the patient data and 5-year survival probabilities under various therapy scenarios estimated.
Results: A total of 459 patients developed AIDS and 346 died during 12 503 person-years of follow-up. HIV-related mortality decreased from 3.8 to 0.7 per 100 person-years between 1996 and 2000 whereas non-HIV-related mortality did not change (0.4 and 0.9, respectively, P = 0.25). For asymptomatic and symptomatic therapy naive patients younger than 50 years with CD4 counts above 10 × 106 and 150 × 106 cells/l, respectively, predicted 5-year survival probabilities were above 90% when HAART was used continuously. This limit was 450 × 106 cells/l when HAART was used during 20 weeks in each 24 week-period of follow-up, and 110 × 106 cells/l when patients delayed initiation of HAART for 1 year after becoming eligible for treatment.
Conclusions: Survival probabilities were high among HIV-infected patients initiating HAART at an early stage of infection. The best therapy strategy is therefore to start HAART at this stage of infection. However, deferring HAART in patients with high CD4 cell counts may be clinically more appropriate given toxicity and adherence problems. The lack of any change in non-HIV-related mortality suggests that toxicity has not yet become a major risk factor for death.
The short term beneficial effect of highly active antiretroviral therapy (HAART) on survival and development of an AIDS-defining illness is well established [1–3]. Not only has the life expectancy of HIV-infected patients increased but also their quality of life has improved [4,5]. In addition the spectrum of causes of mortality is changing as the number of deaths related to opportunistic infections has diminished [6,7].
A significant problem associated with HAART is the adverse effects of drugs which may result in increasing morbidity and a reduced quality of life [4,8,9]. In addition, low adherence to drug regimens may lead to sub-optimal therapy thereby jeopardizing the likelihood of maintaining viral suppression [10–12], which in turn may lead to therapy failure and drug resistance [13,14]. It is therefore currently recommended that antiretroviral treatment is deferred in patients who have high CD4+ T-cell counts or relatively low plasma levels of HIV-RNA or both [15]. Another debated issue is structured therapy interruptions (STI) which, by enhancing HIV-specific immune responses, may contribute to maintaining virologic suppression [16–19].
Several studies have assessed prognostic markers related to progression to death or AIDS. Baseline CD4+ T-cell counts are highly predictive for (AIDS-free) survival in both untreated and treated patients whereas baseline HIV-RNA levels have little additional predictive value in treated patients [20–23]. Increases in CD4+ T-cell counts during treatment with HAART and reaching undetectable levels of viral load are also significantly associated with a better prognosis [22,24,25].
In the present study prognostic markers for survival and progression to AIDS among HIV-infected patients in the ATHENA observational cohort [26] were included in a multivariate hazards model. This model was used to estimate 5-year survival probabilities for patients at initiation of HAART. We know of only one previous study that estimated survival probabilities for patients treated with HAART [27]. These probabilities are important when answering questions regarding life expectancy when patients begin demanding and life-long anti-HIV treatment. In addition, we assessed the effect of HAART taken continuously or discontinuously, which was used as a surrogate marker of therapy success. This allowed us to predict the effect on disease outcome of unstructured treatment interruptions or deferred treatment. Finally we studied the changes in HIV-related and non-related mortality and associated risk factors.
Data used in this study were selected from the ATHENA observational cohort [26]. This cohort consists of HIV-infected patients living in The Netherlands (n = 3908 by 31 July 2001) and using highly active antiretroviral therapy (HAART). At the time of inclusion patients were at least 18 years old and gave informed consent to participate. Monitoring of patients was undertaken in 22 hospitals across the country. At each visit data were collected on case report forms and entered into the database on site. Data were then sent to the central database where consistency checks were performed. Source document verification was performed for 10% of the data and mistakes or missing data were reported back to each site and corrected.
Prospective data collection started in May 1998. From patients who started HAART before that time data were collected retrospectively, including those patients who had died before 1 May 1998. Demographic data were collected at entry in ATHENA. Clinical data focused on HIV-1 infection related events according to the Centers of Disease Control definition [28], the therapeutic and prophylactic drugs used to treat opportunistic infections and the combination and dose of the antiretroviral drugs used and their side-effects. In addition, data on plasma HIV-1 RNA concentration and CD4+ and CD8+ T-cell counts were collected.
The start date T0 of HAART, which in our study defined the start of follow-up, was determined from the data on antiretroviral drug use. HAART was defined as a combination of at least three drugs from at least two classes (nucleoside and non-nucleoside reverse transcriptase inhibitors and protease inhibitors). Patients whose HAART regimen was not recorded before closure of the database (31 July 2001) were excluded from this study (n = 166). Therapy interruptions after T0 were assessed by counting the number of weeks NHAART in which HAART was used in the preceding 24 weeks. In the first 24 weeks after start of the first HAART regimen we assumed a 100% usage of HAART (NHAART = 24). After each period of 24 weeks of follow-up NHAART was adjusted to its most recent value.
CD4+ T-cell counts and HIV-RNA load were measured on average every 12 weeks. Baseline (i.e. at start of HAART) CD4 cell count and viral load were determined by taking the value closest to the start of HAART measured between 24 weeks prior to T0 and 1 week thereafter for CD4 cell counts and 0 weeks after T0 for viral load. Disease status at baseline was defined as the most serious CDC-event (category B or C) in the year prior to T0 and the first 4 weeks thereafter. Additional information was collected on the transmission route (homosexual sex, heterosexual sex, intravenous drug use and other), gender and age at T0. Groups of patients were compared using Wilcoxon Mann–Whitney and χ2 non-parametric tests.
End points in this study were either death or AIDS events occurring as of 4 weeks after start of HAART. A CD4 cell count below 200 × 106 cells/l in isolation was not considered as an AIDS-defining event [27]. Patients who did not die or develop AIDS were censored at 3 months after the last follow-up visit, at the date of closure of the database, or, when analysing progression to AIDS, at the date of death, whichever came first. The period of 3 months corresponded with the median time between two consecutive visits.
Death cases were scored by a panel of three independent physicians (P.R., I.C.G., K.B.) as HIV-related, non-HIV-related (including therapy-related cases) or unknown. This score was based on clinical data at time of death reported by the treating physician and the patient's history of CDC and adverse events. Cases about which the physicians disagreed were discussed by the panel until a consensus score was reached. Mortality was calculated per 100 person-years of follow-up after T0. Poisson's distribution was used to calculate 95% confidence intervals for rates. Expected death rates were calculated for an age and gender matched group from the general Dutch population [29].
A multivariate hazards model was used to find the set of covariates that best predicted the time from start of HAART to onset of AIDS and death. For each patient the hazard for death or AIDS, h(t), after t years of follow-up after T0 is modelled as the product of an underlying hazard h0(t) common to all patients and a function containing patient-specific covariates. In order to estimate the underlying hazard in models with time-dependent covariates we used a discrete-time generalized linear model [30] in which for each patient the follow-up time was split in 3-week intervals, such that the Poisson probability of having two or more events per patient in the same time interval could be neglected. The hazard h(ti) of dying in time interval i is then given by the expression
where the sum runs over all covariates j with corresponding hazard ratios exp[βj(ti)]. The survival probability S(ti) up to time interval i is given by S(ti) = exp[−H(ti)] with H(ti) the cumulative hazard at ti defined as H(ti) = ∑j ≤i h(tj).
Covariates considered for inclusion in the model were disease status at start of HAART, age, gender and transmission route. Antiretroviral pre-treatment before start of HAART was included as a dichotomous covariate indicating whether or not a patient was pre-treated more than 1 year prior to T0 (no significant difference in disease progression was found between therapy-naive patients and patients pre-treated less than 1 year). NHAART was stratified in three categories: continuous use of HAART (NHAART = 24), not continuous but 16 weeks or more (16 ≤ NHAART < 24) and less than 16 weeks (NHAART < 16). We also considered baseline CD4 cell count and viral load and a covariate indicating whether a baseline CD4 cell count was available. An analogous covariate for viral load was not included, as it would be severely biased because pre-treated patients were less likely to have a baseline viral load than therapy-naive patients (Table 1). Parameters were estimated by maximizing the partial likelihood. Covariates were excluded from the model via backward elimination if this did not yield a significantly worse model (P < 0.01, log-likelihood, χ2 test). Wald 95% confidence intervals were calculated for the hazard ratios.
By extrapolating the model beyond the median follow-up time of the study group we could estimate 5-year survival probabilities after initiation of HAART using the hazards model as described. We estimated survival probabilities assuming various therapy scenarios: (a) continuous HAART (NHAART = 24 always), (b) HAART is interrupted for 4 weeks in each 24-week interval of follow-up (by definition NHAART = 24 in the first 24 weeks after T0 and NHAART = 20 thereafter), irrespective of the reason and the temporal pattern of the interruptions, and (c) instead of starting HAART at T0 patients waited for 48 weeks and started continuous HAART thereafter (`deferred HAART', NHAART = 24 in the first 24 weeks of follow-up, 0 in the next 48 weeks, and again 24 thereafter). In this latter scenario T0 is not the start of HAART but the time by which patients were eligible for treatment. Baseline values for the covariates in the hazards model were still determined at this time to allow a direct comparison between the three scenarios. Bootstrapping methods were used to obtain 95% confidence intervals on S(t) and to test the significance of differences between survival probabilities. A risk calculator based on our model will become available via our website (http://www.hiv-monitoring.nl).
All statistical analyses were carried out using SAS version 8.00 (SAS Institute, Cary, North Carolins, USA).
The number of patients in the ATHENA database that initiated HAART was 3742 of which 18 patients were excluded as their age at start of HAART was unknown. Thus our study contained 3724 patients who received HAART of whom 346 died during follow-up. The total follow-up time was 12 503 person-years. Characteristics of the patients at start of HAART are shown in Table 1. Among the 3708 patients who survived more than 4 weeks 459 patients were diagnosed with AIDS during follow-up. Of the 16 patients who did not survive more than 4 weeks nine died whilst the remaining seven patients were censored.
Covariates associated with progression to AIDS are listed in Table 2. The underlying hazard function h0 was modelled as a constant plus the log-transformed time of follow-up which was significantly associated with a reduced risk of developing AIDS [22]. For pre-treated patients the risk of progression to AIDS was 1.91 times larger than for patients who had no or less than 1 year of previous treatment. Each unit increase in log-transformed baseline CD4 cell count reduced the risk of progression to AIDS by a factor 0.62. Patients without a measured baseline CD4 cell count had a hazard ratio of 3.11 compared to those who had one. Gender, transmission category and viral load and age at baseline were not significantly associated with development of AIDS.
The effect on disease progression of having been diagnosed with AIDS in the year prior to start of HAART was the only one that was found to be dependent on time of follow-up after start of HAART. Compared to patients who were not diagnosed with AIDS before initiation of HAART the hazard ratio was 4.22 in the first half year after T0 decreasing to 1.83 in the 2.5 years thereafter, while after 3 years following start of HAART the hazard ratio was no longer significant. A Centers of Disease Control (CDC) category-B event in the year prior to start of HAART was not significantly associated with progression to AIDS after start of HAART. Interrupting HAART up to 8 weeks (16 ≤ NHAART < 24) or more than eight weeks (NHAART < 16) of the preceding 24 weeks was associated with a hazard ratio of 2.03 and 4.94, respectively, compared to continuous treatment with HAART.
In addition to the covariates associated with progression to AIDS two extra covariates were associated with survival, transmission via intravenous drug use and age at start of HAART (Table 2). In contrast to progression to AIDS, survival was not directly associated with time of follow-up. The hazard ratio of having experienced a CDC category-C event in the year prior to start of HAART was 14.5 in the first half year after initiation of HAART decreasing to 2.39 in the 2.5 years thereafter. Hazard ratios associated with treatment interruptions were 4.00 (16 ≤ NHAART < 24) and 7.28 (NHAART < 16).
Estimated 5-year survival probabilities as a function of baseline CD4 cell count and age for therapy-naive patients who are not intravenous drug users are given in Figure 1. Figures 1a and 1b show survival probabilities for patients without and with an AIDS-defining disease, respectively, in the year prior to the start of HAART who use HAART continuously (therapy scenario a). For patients younger than 50 years with CD4 cell counts above 10 × 106 or 150 × 106 cells/l (see Figure 1a and 1b), respectively, the predicted survival probabilities are above 90%. Estimated 5-year survival probabilities for patients without prior AIDS-defining event who interrupt HAART during 4 weeks of each 24-week interval of follow-up (scenario b) are only above 90% when CD4 cell counts at start of treatment are above 450 × 106 cells/l (Figure 1c). When the same group of patients defers HAART for 48 weeks and uses continuous HAART thereafter patients with CD4 counts above 110 × 106 cells/l have a 90% 5-year survival probability (scenario c).
Of the 346 deaths in our study group HIV-related mortality was scored as the most probable cause of death in 191 (55%) cases whereas in 97 (28%) cases the cause of death was non-HIV-related of which seven (2%) were therapy-related. In 58 (17%) cases the cause of death could not be determined. HIV-related mortality per 100 person-years of follow-up since start of HAART was 3.8 [95% confidence interval (CI), 2.4–5.9] in 1996 and decreased to 0.7 (95% CI, 0.5–1.1) in 2000 (P < 0.01) (Fig. 2). Non-HIV-related mortality did not change over time, 0.4 (95% CI, 0.0–1.3) and 0.9 (95% CI, 0.6–1.3), respectively (P = 0.25).
Covariates associated with either HIV-related or non-related death are shown in Table 3. No significant association was found between intravenous drug use and HIV-related death while CD4 cell counts at baseline were not associated with non-HIV-related death. Pre-treatment with antiretroviral drugs, a CDC category-C event in the year prior to start of HAART as well as discontinuous use of HAART were associated with an increased risk of HIV-related and non-related death.
Our study shows, in accordance with previous findings, that clinical markers associated with a higher survival probability and a slower progression to AIDS are a high baseline CD4+ T-cell count, absence of CDC category-C events before start of HAART and no or limited prior treatment with antiretroviral drugs. Age and intravenous drug use are significant predictors for progression to death but not for development of AIDS. In addition, continuous HAART is associated with slower progression to death and AIDS in comparison with interrupted HAART. The large difference between the AIDS and survival model in parameter values associated with an AIDS-diagnosis in the year prior to initiation of HAART is largely explained by the inclusion of time of follow-up in the first model. To avoid complexity in our model we only included prognostic variables that are measured in routine patient care. Thus our model could easily be applied to other observational cohorts.
In accordance with previous studies [22,23] we did not find a significant association between HIV-RNA levels at start of HAART and subsequent disease progression. Other studies showed that reaching undetectable plasma HIV-RNA levels during HAART is much more strongly related to risk of death and AIDS than pre-HAART RNA levels are [22,24]. In our analyses, however, we did not include viral load during HAART as we aimed to predict survival probabilities at the time of initiating HAART. Furthermore, we did not include haemoglobin and transaminase levels which have been shown to be associated with survival probability [31] since in our data these values were only recorded during follow-up.
By using our model to estimate survival probabilities we found that for young patients starting continuous HAART whilst in a less advanced stage of HIV-infection the 5-year survival probabilities were above 90%. This agrees with the 3-year survival probabilities that were previously found for a similar group of patients and varied between 95.9% and 99.8% [27]. Longer term predictions could be made but since the long-term effects of HAART are still unknown, these predictions cannot be validated with currently available data and might be too optimistic considering the risk of toxicities and resistance.
The effect of treatment on disease outcome is assessed by studying therapy interruptions, which reflect both failure to suppress viral load or to increase CD4 cell counts and toxicity-driven switches. This analysis does not aim at drawing conclusions about the effect of a treatment strategy adopted at start of HAART. The high survival probabilities for patients with high baseline CD4 counts using interrupted HAART confirm that occasional treatment interruptions shorter than 3 months do not increase the risk of death [19]. Our results are also compatible with STI studies which show that short-term disease progression does not change or may even improve slightly [16–18]. However, therapy interruptions in our cohort are largely unstructured and occur for a longer period of time (median duration 2 months, data not shown) than in previous reports. Moreover, therapy may have been interrupted because of toxicity or therapy failure, the latter two being associated themselves with an increased risk of death and AIDS. Other studies have shown that therapy failure is the reason for about 10% of the therapy interruptions within 1 year after start of HAART, and toxicity for about 30%. This latter percentage increases with each calendar year following the introduction of HAART [26,32,33]. Untangling the pure effect of STI from these other therapy interruptions is difficult in the settings of an observational cohort.
A possible underestimation of the effect of therapy interruptions is caused by patients who die within 24 weeks after initiating HAART as, by construction, therapy interruptions are not counted. We argue, however, that the effect of interruptions on disease progression is not instantaneous but only manifests itself after some time.
The optimum time to initiate HAART in asymptomatic patients is an issue that is hard to resolve [15,27]. The beneficial effect on immune restoration should be balanced against the risk of drug-related toxicities and development of drug resistance [15,34]. Our model could predict survival probabilities for patients who deferred initiation of HAART for 1 year after becoming eligible for treatment, although these predictions were not based on a dedicated study on deferring treatment. We approximated the decrease in CD4 counts in this year by an increased risk of death due to the absence of treatment. This risk is probably overestimated as treatment interruptions in our data were always during HAART. Compared to patients of the same age and CD4 cell count who initiated HAART immediately after becoming eligible for treatment, the difference in survival probabilities was a few percentage points when CD4 cell counts were above 110 × 106 cells/l. Although small, this difference was significant and compatible with previous findings that initiating HAART in patients with CD4 cell counts above 350 × 106 cells/l significantly delayed clinical progression [34].
From 1996 until 2000 the mortality amongst HIV-infected persons in the ATHENA cohort declined. A similar reduction has been observed in other studies and is largely explained by the introduction of HAART [2,3]. However, part of the decline might be attributed to changes in the infected and treated population during these years, as it shifted towards one in a less advanced stage of HIV-1 infection at the start of HAART with a growing fraction of therapy-naive patients. Mortality rates in 2001 were unreliable as not all follow-up data are available yet.
Non-HIV-related mortality was two to three times higher than in the general population [7]. Part of this excess can be explained by the seven proven and approximately 25 possibly therapy-related causes of death. Moreover, the HIV-infected and treated population is not representative of the general Dutch population, as there are relatively more intravenous drug-users who have a higher risk of dying of non-HIV-related causes.
Although misclassification of causes of death may limit interpretation of the results, the stable incidence of non-HIV-related causes over the years suggests that toxicity has not yet become a major cause of death. This may, however, change in the future when the long-term consequences of HAART become more clearly recognized. Thus, the recognition and careful recording of therapy-related toxicity and deaths remains of utmost importance.
In conclusion, using only covariates known at baseline, we could predict survival probabilities for patients initiating HAART under various therapy scenarios. Our model predicted that using HAART continuously is the best scenario. Deferring HAART for 1 year after becoming eligible for treatment and using continuous HAART thereafter is, according to our model, better than using interrupted HAART. However, absolute differences between 5-year survival probabilities in these three different scenarios were small for asymptomatic patients younger than 50 years with high levels of CD4 cell counts. Considering the risk of toxicities and adherence problems deferring treatment might therefore be acceptable.
Sponsorship: This study was supported by the National Health Insurance Council (grant number 97-46486), Amstelveen, The Netherlands. A.C.G. is supported by The Royal Society, London, United Kingdom. F.D.W. is supported by the Wellcome Trust, London, United Kingdom.
Members of the ATHENA Project: Clinical and Epidemiological Working Group: W. Bronsveld, Medical Centre, Alkmaar; H. Weigel,* K. Brinkman, P. Frissen, Onze Lieve Vrouwe Gasthuis (OLVG), Amsterdam; J. ten Veen,* M. Hillebrand, S. Schieveld, OLVG, Prinsengracht; J. Mulder,* E. van Gorp, P. Meenhorst, Slotervaart Hospital, Amsterdam; A. van Eeden, Jan van Goyen Kliniek, Amsterdam; S. Danner,* F. Claessen,* R. Perenboom, Academic Hospital, Vrije Universiteit, Amsterdam; J. K. Eeftinck Schattenkerk, E. Gisolf, M. Godfried, J. van der Meer, J. Nellen, D. Notermans, T. van der Poll, M. van Praag, J. Prins, P. Reiss, M. Reijers, T. Ruys, M. van der Valk, A. Verbon, F. Wit, Academic Medical Centre, Amsterdam; C. Richter,* R. van Leusen, Hospital Rijnstate, Arnhem; R. Vriesendorp, Westeinde Hospital, The Hague; R. Kauffmann* and E. Kogger, Hospital Leyenburg, The Hague; B. Bravenboer, Catharina Hospital, Eindhoven; C. ten Napel,* K. Pogany, Medisch Spectrum Twente, Enschede; H. Sprenger,* G. Law, University Hospital, Groningen; R. W. ten Kate, Kennemer Gasthuis, Haarlem; M. Leemhuis, Medical Centre, Leeuwarden; F. Kroon,* E. Schippers, University Medical Centre, Leiden; G. Schrey,* S. van der Geest, A. van der Ven, University Hospital, Maastricht; P. Koopmans,* M. Keuter, D. Telgt, University Hospital, Nijmegen; M. van der Ende,* I. Gyssens, S. de Marie, Erasmus University Medical Centre, Rotterdam (EMCR); J. Juttmann,* C. van der Heul, St. Elisabeth Hospital, Tilburg; M. Schneider,* J. Borleffs, L. Hoepelman, C. Jaspers, University Medical Centre, Utrecht; W. Blok, Hospital Walcheren, Vlissingen. (*site co-ordinating physicians.)
HIV; antiretroviral therapy; survival; AIDS; prognosis; HIV-related mortality; mathematical models
© 2003 Lippincott Williams & Wilkins, Inc.
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I'll be writing about news from Lansing that impacts sportsmen (this means ladies as well), talking about things I find when I go overseas to visit my children, and adding your comments into the mix. Because fishing really interests me, I will tend to concentrate in that area, but will digress on such topics as gun control which is in the news a lot right now, some of the animal rights stuff trying to take some freedoms away from us, ecology, and of course your comments.
Wednesday, December 19, 2012
Do we need automatic guns?
The military and police are about the only groups that would have a need for them. I(This is pursuant to conversations I have heard.) I agree.
Hunters need a bolt action or pump to shoot game. One good friend, Tom Lounsberry who resides on a farm in the thumb area often hunts with a single shot shotgun. He can empty a spent round a reload quicker than many can rack another round in the the gun's clip.
But the other side of the argument is if autos or semi autos are deemed illegal, that's just one step in outlawing all guns. Give them an inch and they'll take a yard is the conclusion of gun rights advocates.
The NRA, always a proponent of about any firearm that comes down the road has been silent on this issue since the shootings occurred.
They plan to hold a news conference December 21 to announce their position. In the past those announcements have always brought with them, frustration and anger on both the right to bear arms side as well as the opposition.
It's time to fish or cut bait as the saying goes. I don't think we can have it both ways. They are either legal or not.
Many stores are pulling them off shelves and gun racks. Some are refusing to sell them anymore. Indeed, these next few days and weeks are going to be telling regarding the second amendment and gun owners rights.
1 comment:
I am an NRA life member and supporter and believe in the Right to Bear Arms. However we don't need auto loading long guns with huge clips for any purpose except in war. I will never get rid of my Ruger 10/22. It is a fine squirrel getter though I don't hunt anymore. But I still go to the range and enjoy poking holes in bulls eyes. Is limiting autoloading rifles the foothold to eliminating shotguns that we use for hunting and home defense?ReplyDelete


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Is there a bike shop anywhere near Paddington station????
Bike Forum
Paddington Bike Shop
Nearest one I think would be the Cycle Surgery concession in Selfridges.
Yes - Fudge Cycles on the Harrow Road. 10-15 mins walk from Paddington
What are you after? They're big into folding bikes, though that's not all they do.
oops. my apologies.
Not heard of fudge and I used to live up the Harrow Road (but no that far up)
I had assumed that the OP was thinking townwards side of paddington.
I must pootle up to fudge and check them out.
EDIT> Although Walkit.com says that selfridges is closer than fudge cycles.
theres an evans in westbourne grove past hertford rd
I was after a new rear light. I often have half an hour to spare at Paddington so was just wondering if there was anywhere to spend that time.
Nearest one I think would be the Cycle Surgery concession in Selfridges.
Closed down years ago Stoner, do keep up! They have one at Gt Portland St though.
Half Pipe on Golborne Rd - just off Ladbroke Grove north.
Really top blokes and a great skate/bmx/snow lifestyle shop too.
Ask for Johnny or Nick.Posted 5 years ago #
Topic Closed
This topic has been closed to new replies.


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Top memory module manufacturer OCZ Technology has announced its new PC-4800 Platinum Elite Edition memory modules for enthusiasts and overclockers. While the company already has 600MHz DDR products in the lineup, the new modules require lower voltage, which may indicate better overclocking potential. Furthermore, the new modules use Samsung TCCD chips, well-known among overclockers and enthusiasts.
"Due to the popular demand for TCCD ICs OCZ has decided to release a new product using improved speed grading to cater to the detailed requirements of enthusiasts," said Dr. Michael Schuette, Director of Technology Development at OCZ Technology.
OCZ's PC4800 Platinum Elite Edition memory modules are rated to operate at 600MHz with CL2.5
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Record rains cause trouble in Central Vermont
Mark Collier / Staff Photo John Mayo (right) and backhoe operator Tommy Tucker of Tomco Excavating in Northfield discuss the optimum placement for the boulders they were placing in-between a bridge on Route 12A in Roxbury and the railroad line that runs along 12A between Northfield and Roxbury. The boulders were being placed in an effort to ensure the integrity of the bank of the First Branch that also follows 12A South.
A storm brought record rainfall in several Central Vermont towns Friday night into Saturday.
More than 2½ inches of rain drenched Waitsfield and Waterbury on Friday, according to the National Weather Service, and more than 1½ inches fell on several other locales across the state in a 24-hour period.
The rain caused flash flooding Friday night along Route 12A south of Roxbury, as the Flint Brook breached its banks and threatened the Amtrak railroad line, a house and the road, according to Selectman Steve Twombly.
Emergency crews were called to the area shortly after 9:30 p.m. Friday, and a construction crew was on the scene Saturday morning to shore up the railroad tracks and the Route 12 bridge.
Luckily it did not get as bad as we had thought it might, Twombly said. So there was not much damage. The fear was that the wall would break, but it did not.
The wall he referred to, which was built by the railroad in the 1840s to redirect the current of the Third Branch of the White River, was blown apart by flooding from Tropical Storm Irene a year ago. The walls failure wiped out the historic Roxbury fish hatchery.
That was the third time in the last 10 years that this wall which survived the 1927 flood has caused trouble when hit by high water.
The water was topping the wall Friday night, but never really threatened to sweep it away as it did during Irene, Twombly said. The way it channels the water, however, is causing ongoing problems and is preventing the rebuilding of the fish hatchery.
The fear is, that until this wall situation is figured out, its foolish to rebuild (the hatchery), he said. People know it; we just cant figure out whos going to take responsibility.
Twombly said the brook was diverted by the railroads when they were doing a lot of re-channeling of local streams and rivers to build tracks, and the tracks now act as a dam. Because the structures are not owned by the state or the town, a potential permanent fix would not qualify for federal emergency funding, and there is uncertainty over how to proceed.
In this case it doesnt quite fit the standard configuration of ownership, Twombly said, meaning there is not one group that has the power or resources to get the problem corrected.
The rain broke several records across the state for the most rain that ever fell on the date of Oct. 19, and was the second-highest rainfall total in Burlington so far in 2012, with 1.72 inches falling in 24 hours. That is second only to Sept. 5 of this year, when 1.92 inches fell, and broke the old Oct. 19 record of 1.13 inches.
Montpelier recorded 1.64 inches, breaking the old record of .63 inches, set in 2007, according to National Weather Service Observing Program leader Nathan Foster.
That was an easy one to get, he said of the rainfall total. It was only a matter of time.
Foster said several other records were broken across the state, although many of them were at stations that have been set up relatively recently in the last 15 or 20 years and are run by volunteers.
The total of 2.02 inches of rainfall recorded Friday in Northfield was reported by a trained observer with equipment that is quality-control tested by the National Weather Service. The 2.56 inches that fell in Waterbury were recorded by a volunteer station that does not have the same quality control, while a record 1.13 inches logged at Springfield Airport was recorded by a more controlled automated system, which was set up in 1997.
So, the records in many areas should be taken with a grain of salt, as they may not reflect recordings from a long stretch of time, and may not reflect major weather events like the 27 or 73 floods.
Some of (the records) are a little underwhelming, he said.
Either way, Foster said, the National Weather Service looks at the numbers and eliminates any that appear to be unbelievable.MORE IN Central VermontBRATTLEBORO Brooke Shields gift list is sweetening a Vermont family farms sale of maple syrup. Full StoryMONTPELIER City councils from Barre and Montpelier have placed the Central Vermont Public... Full StoryWoodstock After more than four hours of sometimes-tense courtroom arguments that raised serious... Full Story
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- Bureau of Reclamation Announces $100,000 in Recovery Act Funds for Non-Native Fish Removal from Utah Lake
Bureau of Reclamation Announces $100,000 in Recovery Act Funds for Non-Native Fish Removal from Utah Lake
Media Contact: Joan Moody, 202.208.6416
Lisa Iams, 801.524.3673
For Release: August 30, 2010
WASHINGTON, D.C. - The Provo Area Office of the Bureau of Reclamation, an agency of the Department of the Interior, awarded a contract under the American Recovery and Reinvestment Act (ARRA) of 2009, totaling $100,000 to the Central Utah Water Conservancy District (CUWCD) of Orem, Utah, for the removal of non-native fish from Utah Lake to aid in the recovery of the native June sucker (Chasmistes liorus).
The June sucker is endemic only to Utah Lake, located in north central Utah. In 1986, it was federally listed as an endangered species due to significant population decline associated with water development, impacts on natural habitat, and competition with non-native fish, specifically the common carp (Cyprinus carpio). The June Sucker Recovery Implementation Program (JSRIP) was established to recover the June sucker while allowing for continued water development.
Because of the significant impact of non-native carp on the June sucker, the multi-agency JSRIP has supported projects to investigate the feasibility of physically reducing the common carp population in Utah Lake, monitor carp movement, and evaluate the potential of various methods for controlling carp.
The Central Utah Water Conservancy District, a participating member of the JSRIP, has been identified by Reclamation and other JSRIP participants as the responsible agency for a general account used to gather funds to support recovery work outlined in the annual JSRIP guidance. This ARRA supported project will allow for the removal of up to 500,000 pounds of carp from Utah Lake.
"Reclamation continues to work collaboratively with the JSRIP partners to identify program activities that will assist in the recovery of the endangered June sucker," said Michael L. Connor, Reclamation commissioner."Successful carp control within Utah Lake would significantly improve the existing habitat conditions and aid in the recovery of the June sucker."
The American Recovery and Reinvestment Act enacted in 2009 gave $3 billion to the Department of the Interior.
The ARRA funds represent an important component of the President's plan to jumpstart the economy and put a down payment on addressing long-neglected challenges so the country can thrive in the 21st century. Under the ARRA, Interior is making an investment in conserving America's timeless treasures - our stunning natural landscapes, our monuments to liberty, the icons of our culture and heritage - while helping American families and their communities prosper again. Interior is also focusing on renewable energy projects, the needs of American Indians, employing youth and promoting community service.
"With its investments of Recovery Act funds, the Department of the Interior and its bureaus are putting people to work today to make improvements that will benefit the environment and the region for many years to come," Secretary Salazar said.
Secretary Salazar has pledged unprecedented levels of transparency and accountability in the implementation of the Department's economic recovery projects. The public will be able to follow the progress of each project on www.recovery.gov and on www.interior.gov/recovery. Secretary Salazar has appointed a Senior Advisor for Economic Recovery, Chris Henderson, and an Interior Economic Recovery Task Force to work closely with Interior's Inspector General and ensure the recovery program is meeting the high standards for accountability, responsibility, and transparency set by President Obama.
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Reclamation is the largest wholesale water supplier and the second largest producer of hydroelectric power in the United States, with operations and facilities in the 17 Western States. Its facilities also provide substantial flood control, recreation, and fish and wildlife benefits. Visit our website at www.usbr.gov and follow us on Twitter @USBR.


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Hotel Marvin: Find photos, reviews, information, amenities and compare prices for 3 stars hotels in Montepulciano, Italy.
Hotel Marvin has a 24-hour reception, a mineral bath and a bicycle rental. Just a short walk from Terme di Montepulciano, it offers comfortable rooms equipped with a private bathroom, a refrigerator and heating.
Hotel description
This 3-star hotel provides luggage storage, room service and a safe. The on-site spa offers a variety of treatments and a chance to relax.
Every room at Hotel Marvin Montepulciano provides a telephone and all the essentials for a comfortable stay. There are also several rooms geared towards families.
Each morning, guests can wake up to breakfast served by Marvin Hotel before setting out to see what the local area has to offer. For guests with day trips planned, the hotel offers packed lunches if required.
Set in the Tuscany Wine Region, guests of Hotel Marvin can easily sample the region's specialties and everything it has to offer. Val di Chiana and Palazzo Piccolomini are within a 20-minute car ride from the hotel.
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A complete line of moving supplies for the do-it-yourself mover in Long Beach, CA. U-Haul moving boxes are specifically designed to make packing and loading easier. We have products to meet all of your moving needs. Whether its boxes, packing tape, bubble wrap or any other type of packing supplies, U-Haul wants to make moving that much easier for you. We offer free shipping to Long Beach, CA, 90813 or anywhere within Canada or the continental U.S. on all orders over $50, or choose in-store pick up at First Class Auto for same-day service!
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Activities and Events
WINTERFEST EVENTS PLANNED: Student Government in collaboration with the Student Center Administration and Campus Life will host a week of fun events during WinterFest. Below are the upcoming events:
- Outdoor Winter Celebration: Thursday, January 17, from 12 - 4 p.m., on the outdoor patio at the Student Center. Students will have an opportunity to listen to good music brought to them by Channel 95.5's Bomb Squad from 12 - 2 p.m. Students will see an ice carving, receive a caricature drawing of themselves, and be able to *ice skate outside (*weather permitting) while enjoying a free cup of hot chocolate.
- Movie Night: Friday, January 18, 7:30 - 11:30 p.m., in the Student Center Auditorium. After a long week of hard work, students will be able to relax at one of the two movie showings of "Hotel Transylvania" - with free popcorn!
Please contact Desmond Miller, student body vice president at email@example.com or call 487-1471 with any questions.
* HONORING JULIA NISWENDER: The Department of Communication, Media & Theatre Arts will host an evening program to honor Julia Niswende, Thursday, January 17, 6 p.m., in Quirk and the Sponberg Theatre. Share memories of Julia Niswender - as an EMU student with a double major in communication and electronic media & film studies - with her family, campus friends and fellow students. The program will include remarks from CMTA faculty who enjoyed the energy and spirit she brought to their classrooms plus a photo journey of a recent Extended Programs trip Julia took with fellow students to New York City. The campus community is invited to attend. Light refreshments will be served. For more details, call 487-3130.
MARTIN LUTHER KING CELEBRATION 2013: Tickets are now on sale for the 27th Annual Dr. Martin Luther King, Jr. President's Luncheon, to be held Monday, January 21, in the Student Center Grand Ballroom. Doors open at 11:30 a.m., and the program starts at 11:45 a.m. The distinguished guest and keynote speaker is anti-racist activist/essayist, author and educator Tim Wise. Prices for luncheon tickets are $10 for students; $20 for faculty/staff/community members. Tickets can be purchased at the EMU Convocation Center ticket office and the Student Center ticket office, located on the 1st floor of the Student Center. Go to the MLK 2013 Celebration homepage or contact Ron Reid at 487-2282 for more information.
* RETIREMENT RECEPTION FOR JUDY STOKES: Please join the College of Health and Human Services (CHHS) as they say farewell to Judy Stokes who is retiring after 23 years of service at EMU. A retirement reception will be held on Friday, January 25, from 3 - 4:30 p.m., in the Marshall Gathering Room (Room 374). Judy has provided the CHHS with many years of dedication, efficiency, organization, management skills and good spirit. Please join the CHHS in wishing her a wonderful retirement and gratitude for all her service to EMU..
PANEL DISCUSSION: As part of Black History Month, the Department of Africology and African American Studies presents keynote speaker Ravi Perry, Thursday, February 7, 1 - 4 p.m., in Room 310AB of the Student Center. Perry will talk about "President Barack Obama's Re-election: demography, race relations & emerging political issues." Panelists include Barbara Patrick, Eric Brown, Joseph Engwenyu, Ravi Perry, Gregg Barak and Robert Perry with Victor Okafor moderating. During the event, the winners of a student essay contest on Obama's presidency to be announced. Free refreshments will be available. This event is LBC credit approved. For more information, contact Victor Okafor at email@example.com.
SESI ENTREPRENEURSHIP CONFERENCE: The Center for Entrepreneurship at the College of Business is proud to present the Sesi Entrepreneurship Conference, Friday, February 8, in the Student Center. The Collegiate Entrepreneurs' Organization of EMU is hosting the event and students and faculty are invited to listen to entreprenaurs as they share their successes and failures. The Skandalaris Business Plan Competition will also be held the conference which includes a continental breakfast and a sit-down lunch. The event is FREE but online registration is required. ALL EMU students and faculty and staff are invited to attend. To register or read more about the conference, go to Sesi Entrepreneurship Conference homepage or contact Jessica Smith of CEO for more details via email at firstname.lastname@example.com. (02/05)