text: Opinions leaguewide have been mixed on the subject of whether or not Marshawn Lynch could be facing a suspension folllowing his DUI arrest in the wee hours of July 14. But the consensus among PFW's sources seems to be that the Seahawks' star running back is, at the very least, more likely than not to miss a couple of games. That it was his first DUI offense could bode well for Lynch, since commissioner Roger Goodell does not typically suspend first-time offenders under the league's substance-abuse program. But a punishment based on the league's personal-conduct policy — which was the case when Lynch was suspended for three games in 2009 as a member of the Bills after pleading guilty to a misdemeanor weapons charge — remains a very real possibility. Whatever the case, Lynch's scheduled Aug. 14 arraignment figures to be a training-camp distraction that will be very difficult to ignore.


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So you are looking for the best vapor e cigarette in the market? And how are you supposed to know which one is the best for you? Is it the one your friend referred to you or the one your instincts preferred? Well, you first need to assess yourself and figure out what type of a smoker you are. Whether you fall in the category of an all time smoker, a little better than that and can manage with lesser cigarettes or you need the cigarettes after every couple of hours in a day.
There are various types of e cigarettes designed for each type of smoker. If you smoke heavily Talon e cigarette starter kit is just the right choice as it uses a very advanced technology and its tank system gives a perfect output. If you are a mild smoker you certainly do not need powerful e cigarettes. For a mild smoker using Talon would feel like using the best vapor e cigarette. If you are a heavy smoker you would need a higher performance for in which case G2 could be a good choice. And for the "once in a blue moon" smoker Revolver Light would do the job. It is disposable, comfortable to use and gives a great sensation of using a traditional cigarette.
Apart from this you need to also take into consideration the brand you plan to purchase from. Most of the times you would find e cigarettes are sold online. Now-a-days even wall-mart and retailers have started keeping e cigarettes but the choices offered are limited. So while choosing online you might be overwhelmed with the variety and at the same time might face a challenge to pick the best vapor e cigarette amongst them. In such a situation it is best to go through the reviews of the customers of various brands online. Good e cigarettes have high ratings, high trust factor, offer longer warranties and most importantly are old in the market with a good shipment service. They are made using the best quality substances. Their customer support is efficient and quick.
If you are on serious lookout for the best vapor e cigarette, it is advised to visit ecigscorner.com where you can find long warranty of e cigarettes with details about their range, shipping, flavors available, and the reviews of people who are actually using it. The e cigarettes have changed the concept of smoking rather we can say that we do not smoke at all now because we just "vape" the cloud of vapors. A good vapor e cigarette is the requirement of every modern e cigarette smoker. And if by just a few easy clicks we can get these e cigarettes to save our own lives, then these are worth a shot. It is reasonable to quit the traditional cigarettes and replace them with the e cigarettes as we continue to get the essence of the traditional cigarettes which is the nicotine. And to add on there is no trace of tar to damage our system.
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text: × Please take a short survey to help us improve our data-related literature resources. Search Results Studies Variables Publications (1) Your query returned 1 citations. Sort by: Pub Date (newest) Title Recent Additions Author Clear All Pub. Year Citation 1. 2006 Collins, Lauren G., Parks, Susan M., Winter, Laraine . The state of advance care planning: One decade after SUPPORT. American Journal of Hospice and Palliative Medicine. 23, (5), 378-384. Full Text Options: DOI Worldcat Google Scholar Export Options: RIS EndNote XML Results 1 - 1


text:
Melgisorb Ag is a versatile dressing that can be used on many different wounds - your nurse or doctor will know. Typical wounds that are treated with Melgisorb Ag are
Thank you for contacting Mölnlycke Health Care! We will get back to you as soon as possible.
Mölnlycke Health Care's Patient Site. The materials and information in this web site are in no way intended to replace the professional medical care, advice, diagnosis or treatment of a doctor. The web site does not have answers to all problems and Mölnlycke Health Care makes no warranty or guarantee as to the completeness of the information provided. Answers to specific problems or conditions may not apply to everyone. If you notice medical symptoms or feel ill, you should consult your health care professional. For further information see our Legal notice.


text:
|10.01.2011 - ?MKB launches new index to attract Middle Eastern capital
|From Todayszaman.com: The ?stanbul Stock Exchange (?MKB) launched its first Participation Index comprising 30 listed companies in line with a strategy to attract interest in the countrys Islamic finance sector. The ?MKB on Thursday hosted the presentation and signing ceremony of the Participation Index. Bizim Securities will serve as the consultant of the Participation Index, which some have also termed the Islamic Index. Association of Turkish Participation Banks (TKBB) President Fahrettin Yah?i spoke during the ceremony at the ?MKB and stressed the importance of the participation banks experience in stock trading..............................................Full Article: Source


text:
Detection of extended-spectrum beta-lactamases in E. coli and Klebsiella spp. by isoelectric focusing and PCR
Abstract number: p1414
Oksuz L., Gurler N.
The aim of this study was the detection of beta lactamases types in extended spectrum beta lactamases producing E. coli and Klebsiella spp strains. The study strains consisted of 12 E. coli and 32 Klebsiella spp (28 K. pneumoniae and 4 K. oxytoca) isolated from various specimens of patients hospitalized in different units (Intensive Care, Hematology, Oncology, Neonatology, Transplantation and Pediatric Surgery Units) of the Istanbul Medical Faculty between July 2002March 2004.
Antimicrobial susceptibility tests were performed by disc diffusion according to the CLSI guidelines. MICs of cefotaxime and ceftazidime were determined by the agar dilution method and by the E-test ESBL. Isoelectring focusing was performed by the method of Matthew et al (J Gen Microbiol, 1976). Polimerase chain reaction was performed using primers specific for the bla TEM, blaSHV and blaCTX-M genes. Conjugation was carried out by broth mating. A rifampicin-resistant E.coli strain (J62-2) was used as the recipient. Plasmid extraction was performed by the alkaline lysis method.
Resistance to imipenem or meropenem was not detected. Amikacin was the second most effective antibiotic against all strains, after carbapenems. All isolates demonstrated an ESBL phenotype using the double-disc synergy test. MIC50 and MIC90 for cefotaxime were found 16 mg/ml and 64 mg/ml in Klebsiella spp and E.coli strains, respectively. IEF results indicated that all isolates produced 14 beta lactamases. Isoelectric points of the isolates were between 5.49.0. Among K. pneumoniae and E.coli strains, rates of TEM, SHV, CTX-M beta lactamases were found 64.3%, 92.9%, 67.9%; 66.7%, 25%, 83.3%, respectively. The profiles generated with ERIC-2 PCR primer contained several bands, ranging in size from 170 to 1500 bp. Ten, three and six groups were separated for K. pneumoniae, K. oxytoca and E. coli, respectively. Thirty-one of the isolates (70.45%) were able to transfer their resistance to recipient E. coli strains by conjugation. Twenty of the transkonjugants (64.5%) were found to carry only one plasmid (>48a). Eleven strains (35.5%) harbored more than one plasmid, with sizes ranging from 10 to 100 kb.
In conclusion, we found that CTX-M was more common than TEM and SHV beta lactamases in E. coli strains isolated from patients hospitalized in Istanbul Medical Faculty, however SHV was the most common beta lactamase in K. pneumoniae. The present work was supported by the Research Fund of Istanbul University. Project no T223/06032003.
Session Details
|Session name:
|XXIst ISTH Congress
|Oxford, UK
|Presentation type:
|Back to top


text:
Frank M. Wheeler, 93, of Amarillo died Wednesday, Nov. 14, 2007.
Private family graveside services will be at 2:30 p.m. Saturday in Memorial Park Cemetery with John Wagoner officiating. Memorial service will be at 3:15 p.m. in Craig Memorial Living Center, with visitation to follow. Arrangements are by Memorial Park Funeral Home, 5400 Bell St.
Mr. Wheeler was born Jan. 7, 1914, in Throckmorton to Charles Garnet and Clara Maude Self Wheeler. He grew up in Amarillo and graduated from Amarillo High School in 1932. He then went to Amarillo College to start on a degree in accounting. In 1934, he married Clorine Grammer in Amarillo. She died in September 1988. He later married Bernice Carroll in 1994. She died in February 2000. He was one of the owners of Wheeler Brothers Auto Parts on Route 66 in the early 1940s. He retired after more than 15 years of service to the Chevron Oil Co. After his retirement, he worked with his son Jerry as warehouse foreman at Wheeler Municipal Supply for more than 10 years. He was an avid reader and loved playing dominoes, bingo and any board game he could find.
He was preceded in death by his parents; both spouses; four brothers; three sisters; a son, Larry Frank Wheeler; and two grandchildren, David Craig Wheeler and Kristie Lynn Wheeler.
Survivors include two sons, Jerry Wheeler and wife Sandy and George Carroll and wife Betty, all of Tanglewood; a daughter, Beth Price of Amarillo; three grandchildren, Darren Wheeler and wife Michelle of Stafford, Va., Michelle Black and husband Bo of Amarillo and Mason Price and Autumn of Austin; six great-grandchildren, Ali Wheeler, Chloe Wheeler, Rustin Holcomb, Riley Velasquez, Rayden Velasquez and Shad Price.
The family suggests memorials be to Odyssey Health Care, 6900 W. Interstate 40, Suite 150, Amarillo, TX 79106, Craig Methodist Retirement Center, 5500 W. Ninth Ave., Amarillo, TX 79106, or to the High Plains Food Bank 815 Ross St., Amarillo, TX 79102.
Amarillo Globe-News, Nov. 16, 2007
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text: With a stay at Euromar in Rimini (Rivabella), you'll be minutes from Arenas Water Park and close to Tiberius Bridge. This hotel is within close proximity of Rimini Marina and Church of San Giuliano Martire. Make yourself at home in one of the 49 air-conditioned guestrooms. Your Select Comfort bed comes with Frette Italian sheets. Rooms have private balconies. Bathrooms have showers and hair dryers. Take in the views from a terrace and a garden and make use of amenities such as complimentary wireless Internet access. All-inclusive rates are available at this hotel. Meals and beverages at onsite dining establishments are included in all-inclusive rates. Charges may be applied for dining at some restaurants, special dinners and dishes, some beverages, and other amenities. Enjoy a satisfying meal at a restaurant serving guests of Euromar. Quench your thirst with your favorite drink at a bar/lounge. Featured amenities include express check-in, express check-out, and complimentary newspapers in the lobby. Limited parking is available onsite. The recreational activities listed below are available either on site or nearby, fees may apply.


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This UK trailer for Sega's new action game Bayonetta, features tons of provocative images and gameplay. Director Hideki Kamiya, of Devil May Cry fame, helms this project with developer PlatinumGames which is scheduled for a 2009 release on the PS3 and Xbox 360.
Go ahead you "little Cheshire puss", click play.
Bayonetta UK Trailer
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© 2012 G4 Media, LLC. All rights reserved.


text:
Last December (in "Will Neurocsience Change Education?", I wrote about Dr. M. A. Greenstein of the George Greenstein Institute of Pasadena, California. Greenstein says the institute's mission is to bridge the gap between pure research and the classroom, delivering (in Greenstein's words) "the wisdom and power of truly applied neuroscience into the hands of learners and leaders to make change by design!"
In support of International Brain Awareness Week (March 11-17), Greenstein's group is trying to bring brain awareness to the public through a new arts- and science-based challenge called GLASSIFY! Through April 11, students of all ages, as well as neuroscientists, designers, data visualizers, artists and architects, are invited to submit their 2-D or 3-D vision of an icon for the brain age inspired by inspired by brain imaging, especially, images of spatial memory regions, networks and cells.
An elite jury led by honorary chair and pioneering neuroscientist, Dr. Michael Merzenich, will select one individual and one group submission as winners to be announced in May. The selected concepts will be actualized into blown glass art sculptures by the venerable glass blower Luke Jerram. The glass installations will be exhibited in cities across the U.S.
"We chose to use glass-blown art for the first challenge because it illustrates the fluidity, plasticity, and teamwork needed to activate and develop a brain-aware mind," says Dr. Greenstein. "We've entered the brain age, so it's time for us to draw back the curtain and reveal the workings of our beautiful brains, minds, and deep selves to empower children and adults to use their imagination, generate new ideas, and grow their brains."
"In celebration of Brain Awareness Week and all of our brains, the GLASSIFY! Challenge comes at the perfect time," said Dr. Michael Merzenich, co-founder and chief scientific officer of Posit Science, and Professor Emeritus, UCSF. "I'm honored to be involved in this exciting new project to continue showcasing the wonder of our brains and the importance of keeping them healthy throughout our lives."
More information, including a teacher's packet for classroom submissions, is available at www.inventiobrains.com.


text:
Peter Mavromates doesn't have any movies playing in theaters.
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text:
Scarre, Chris (2010) 'Rocks of ages : tempo and time in megalithic monuments.', European journal of archaeology., 13 (2). pp. 175-193.
Chronology remains a problematic area in prehistoric archaeology but the increasing number and precision of radiometric dates begin to suggest patterns that can be resolved down to the scale of individual lifetimes. The study of megalithic monuments has benefited from these developments but remains hampered by the indirect relationship between the materials that are dated and the structures themselves. Drawing on evidence from France, Scandinavia, and Iberia, it is nonetheless arguable that available patterns of dates suggest an event-like tempo to the construction of megalithic monuments, with large numbers being built within relatively short periods of time. This has implications for typological models and for the social context in which such monuments were designed and built.
|Item Type:
|AMS dating, Chronology, Megalithic monuments, Neolithic, Passage graves, Typology.
|Full text:
|PDF - Accepted Version (249Kb)
|Publisher Web site:
|Publisher statement:
|The final definitive version of this article has been published in the Journal European journal of archaeology, 13/2, 2010 © SAGE Publications Ltd by SAGE Publications Ltd at the European journal of archaeology page: http://eja.sagepub.com/ on SAGE Journals Online: http://online.sagepub.com/
|Record Created:
|11 Nov 2010 15:05
|Last Modified:
|19 Aug 2011 15:34
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text:
Wayne emailed me pics of these BCBG sandals earlier this month. I liked 2 out of 3 the pairs - can you guess which one I disliked? BCBGirls Alga sexy platform sandals in Brunette/Cosmo Pink, $109.95 from Zappos.com BCBGirls China Gold Tan/Ameretto Met Patchwork Stiletto Sandals, $97.95 from Zappos.com BCBG Max Azria Soleil versatile thong sandals, $88 from Zappos.com [phpbay]BCBG sandal, 1[/phpbay] … [Read more...]
Bon Chic Bon Genre Sandals
Dancing Sandals?
Our niece got married last past weekend and one of the guest was wearing these multi rose print sandals from BCBGirls with a cute little sun dress. Not only did she look good, she could actually dance in these 4 1/4" heels! I mean all kinds of dancing including the polka, the chicken dance, electric slide, etc. Here she was dancing in these cute high heels, and I'm not sure I could have even walked in them! I was very envious. BCBGirls Saraff Platform Sandals in Mutli Rose Punch are … [Read more...]
Pointed and Classy Boots
Are these BCBGirls Karen (Women's) - Brown Quilted Stretch boots cool or what? I love the quilted brown pattern that makes them look very stylish and the ornamented design with high heel adds to the look. You can find these Karen ankle stretch boots by BCBGirls at ShoeBuy.com - also available in Vintage Pewter Quilt. [phpbay]fashion boots, 2[/phpbay] … [Read more...]
To Be in BCBGirls
Missy Ward, co-founder of Affiliate Summit, shows off her BCBGirls Tolm heels in London last month. Isn't she stunning? When I asked her about them, she commented that the best feature is the traction on the bottom of the sole. BCBGirls Tolm's are available in Black Kid Leather, Cream or Wheat from Zappos.com with Free Shipping! Flowery d'orsay keeps you looking your prettiest. Leather upper. Floral and leaf ornamentation constructed from leather and lace. Adjustable quarter strap. Lightly … [Read more...]
BCBGirls are Perfect for B2B
I LOVE these hot BCBGirls Kenia Boots. I wear them to work aLL the time with my black flared pants. I love how sexy these boots are and how sexy they make me feel. I can conquer the world with these power boots. They take me from workday to nightclub. I have had them over 2 months and they look like new! EVEN MEN compliment me on these! ~ Kristin, IL Buy Your Own at Zappos! … [Read more...]


text:
The new Thermal Arc® Fabricator® 181i is the only product of its kind. It features MIG, Stick and TIG welding capabilities – complete in one integrated portable package. It's the ultimate compact multi-process welding system that has changed the game.
- Automotive
- Farm and Ranch
- Technical Hobbyists
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- Educational Institutions


text:
Welcome to MHF, JodieR11!
Did you know the following?
Perhaps you know how to differentiate those?
Hey right so I'm currently studying Pure Maths and I'm getting a bit confused on differentiation :/
Just wondering how would I differentiate 16√x and 32/x thanks!
Jodie, it sounds like you don't know how to differentiate anything...
Maybe you could type out an example of a derivative that you DO know, so we can help you from there.
The power rule of derivatives is arguably the first rule that you would learn, so if you can't do that...
I know that you bring the power to the front and then less one. Like, 2x^4 is 8x^3 so the basics! But when it gets to harder things like square roots, negative powers and fractions I know nothing Could you please link me to a site or rules or anything helpful? I have an exam in January and I'm trying to revise now :s thanks for replying and giving help, I'm new to this site and I really think it's helping
so does it just go -31^-2? I have a question which says.....
The curve C has equation y=16√x + 32/x + 2
a. Find the value of dy/dx when x=4
b. Find the equation of the normal to C at the point where x=4
I can find the equation of the normal when I have the coordinates or one coordinate and I have to find the other and only is y=3x^2 - 8x +7 something like that!


text:
from The American Heritage® Dictionary of the English Language, 4th Edition
- n. A crisp, round, compact head of lettuce with light green, tightly folded leaves.
from Wiktionary, Creative Commons Attribution/Share-Alike License
- n. A lettuce cultivar noted for its crunchiness; the most familiar of all lettuces sold in the United States.
from WordNet 3.0 Copyright 2006 by Princeton University. All rights reserved.
- n. lettuce with crisp tightly packed light-green leaves in a firm head
From its pale color.(American Heritage® Dictionary of the English Language, Fourth Edition)
Sorry, no example sentences found.


text:
Ready to put cutting-edge cocktail technology to work in your restaurant's bar? We've got two options you may wish to check out: Vapshot and Palcohol. Either product should bring at least some short-term energy and excitement to a restaurant's bar scene—perhaps more than some restaurants might want—and could also deliver a jolt to the operation's bottom line. The makers of Vapshot bill it as a vaporized spirits system that provides a healthy, safe and ...
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text:
Mini LED Clip Light, Discrete Book Light, Batteries Included
This product is no longer available.
This product is no longer available.
Product Details
- Warranty: Lifetime
- UPC Number: 846568034923
- Color: Silver
- Weight: 0.30 lbs
Mini LED Clip Light, Discrete Book Light, Batteries Included
With its high intensity LED light beam and compact size, this Mini Clip light complete with batteries is perfect for all of those around the house applications that need more light. Behind the TV, next to your circuit breaker, under cabinets, in the car or for reading a book this small size lightweight makes it great for travel as well. With the convenient clip you can attach it almost anywhere for hands free use.
* Batteries are inlcuded
* Batteries are inlcuded


text:
Prosthetic Records is proud to announce the signing of NERO DI MARTE.
Founded in Bologna, Italy in 2007, experimental metallers Nero di Marte debut on Prosthetic Records with their long awaited self-titled release, a unique and experimental approach to structure, sound and atmosphere. Expect a release date in March 2013.
Vocalist / guitarist Sean Worrell commented "We are absolutely thrilled and honored to be working with Prosthetic Records, a label which has had and still has some of the most amazing bands out there in its roster. We are very thankful to them and can't wait for you all to hear our album, which release is long overdue. We will hopefully see you on the road during 2013!"
Duncan of Prosthetic Records Europe added, "It's a rarity to discover such an exciting and forward-thinking new band that equally balances texture, heaviness, intelligence and perfect musicianship as Nero Di Marte does with ease. We're very excited for you to hear the upcoming new album shortly…."
Nero di Marte is the italian name of a pigment, an iron oxide that produces a deep, dark, intense black that when in contact with other colors can permanently coat or noticeably transform them.
Formerly known under the name Murder Therapy, the band signed to Dutch label Deity Down Records to release their debut "Symmetry of Delirium" in 2009, which showed a very personal mix of modern death metal, and have played numerous shows and festivals around Italy and Europe including performances with major acts such as Cynic, Decapitated, The Ocean, Intronaut, Ulcerate, Svart Crown, Red Fang, Jucifer, The Secret and at the prestigious Neurotic Deathfest in Tilburg (NL) with Carcass, Immolation, Six Feet Under, Napalm Death, Bolt Thrower, Origin among many others.
The band's broadened approach to songwriting was already audible in the 2010 self-released Ep "Molochian", which marked a stylistical step forward towards more progressive and atmospheric compositions.
The band then entered the studio to work on their new album in the summer of 2011. It was recorded in roughly 9 days at Regrexion Studios with Michele Trasforini and then was mixed and mastered at Studio73 in Ravenna with producer Riccardo "Paso" Pasini (known for working with Ephel Duath, The Secret, Extrema, At the Soundawn) in November.
During the summer of 2012 the band decided to change its name to Nero di Marte, the name the album was originally given; they now have a few shows in Italy to finish up the year , includine dates with Norway's Virus. and are planning to tour extensively in 2013 to promote the record.
The acclaimed Italian progressive/atmospheric metal quartet NERO DI MARTE have unveiled an advance stream of their sophomore effort "Derivae" prior to its worldwide release on Oct. 27 (North America/UK/EU) and Nov. 1 (G/A/S)! You can listen to the album in its entirety now at RevolverMag.com. Praised for its "supremely thick, groovy, heavy Meshuggah/Gojira-ish yet relentlessly focused riffage" (MetalSucks), the hour-long, seven-track effort was recorded [...]
Italy's experimental progressors NERO DI MARTE's upcoming sophomore effort "Derivae" pushes the quartet towards a post-metal sound with its crushing atmospheres and cinematic flairs, while maintaining their original and "deliciously brutal mix of churning, visceral rhythms and avant-garde, skronky, death metal noise" (MetalSucks). Recorded at Italy's Studio73 with Riccardo "Rico" Passini (Ephel Duath), with whom they [...]
Listen below to "Pulsar," a new song from Italian progressive/experimental metal act NERO DI MARTE's upcoming sophomore release "Derivae." You can also read an exclusive interview with vocalist Sean Worell on the band's influences and their organic recording process at here: http://www.invisibleoranges.com/2014/09/track-debut-qa-nero-di-martes-pulsar/ Three years in the making, "Derivae" — the follow-up to NERO DI MARTE's acclaimed self-titled debut [...]


text:
P. O. Box 362Maineville, OH 45039ph: firstname.lastname@example.com
Should you need further information or want to schedule your free estimate, please feel free to contact us 513-266-3541.
Thank you for
visiting our site!
We look forward to hearing from you!
Copyright 2010 Royalty Cleaning. All rights reserved.
Web Hosting by Yahoo!


text:
There are several options for treating pulmonary neuroendocrine tumors. Patients may receive one or more treatments, such as surgery, hormone therapy, chemotherapy, radiation therapy, and liver tumor embolization (described below).
Surgery is the preferred treatment for most early-stage pulmonary carcinoid tumors. Depending on the size and location of the tumor, doctors may remove the tumor and a portion of lung surrounding it (wedge resection), a lobe of the lung (lobectomy), or an entire lung (pneumonectomy). Surgeons at Memorial Sloan Kettering have experience performing more complex reconstructive surgeries that often permit removal of the tumor while preserving more of the healthy portion of the lung (sleeve resection). Lymph nodes in the chest are often removed during surgical removal of the tumor to determine whether cancer cells have spread. For more information about surgery to remove lung tumors, visit the Lung Cancer overview on our Web site.
Memorial Sloan Kettering offers minimally invasive surgical procedures, including video-assisted thoracic surgery (VATS), also known as thoracoscopy, for the removal of some pulmonary carcinoid tumors. Like laparoscopic surgery or "keyhole" surgery, VATS allows the surgeon to remove the tumor using thin, specialized instruments that are placed in small incisions between the ribs under image guidance. Recovery time and hospital stay is shorter for patients who have VATS compared with those who have traditional "open" surgery.
Chemotherapy and Hormone Therapy
Adjuvant (additional) treatment with platinum-based chemotherapy may be recommended for select patients following surgical removal of pulmonary carcinoid tumors, depending on the stage of the cancer. Because these tumors are so rare, there is no standard chemotherapy regimen for patients with pulmonary carcinoid tumors that have spread to other organs and cannot be surgically removed. Some of these patients may be treated with chemotherapy regimens used to treat small cell lung cancer. Others may be eligible for ongoing clinical trials.
Patients with pulmonary carcinoid tumors that cannot be surgically removed may benefit from monthly injections of a synthetic hormone, octreotide, which controls hormone-related symptoms and may have the potential to slow tumor growth.
Radiation Therapy
External-beam radiation therapy, which delivers radiation from a machine outside of the body, is the most common form of radiation therapy used to treat neuroendocrine lung tumors. Radiation therapy is occasionally recommended following surgery or to relieve symptoms in patients who are not candidates for surgery, particularly when the tumor has spread, or metastasized, to the bone or brain.
Radiofrequency Ablation
Interventional radiologists at Memorial Sloan Kettering have helped to pioneer the treatment of image-guided tumor ablation. This technique uses either heat (radiofrequency) or cold (cryoablation) to treat lung tumors. During ablation, we use CT imaging to place a needle into the tumor, and then apply either cold or heat to destroy tumor cells. This technique requires no incisions and is useful for some patients who are not good candidates for surgery and have isolated tumors.
Liver Tumor Embolization
Embolization, a localized approach to destroying liver tumors, may be used to treat neuroendocrine lung tumors that have metastasized to the liver. The portal vein channels blood and nutrients to the liver, but the hepatic artery directs blood to liver tumors. Guided by imaging techniques such as CT or ultrasound, embolization involves the injection of tiny particles through a small tube, or catheter, threaded into the hepatic artery. These particles block the flow of blood to the tumor, depriving it of the nutrients and oxygen it needs to survive. Embolization may be used alone or in combination with surgery.
Treatment for Advanced Cancers
Because small cell and large cell neuroendocrine tumors are usually found at an advanced stage, treatment often begins with a combination of platinum-based chemotherapy drugs. In the rare instances in which these aggressive tumors are localized, radiation and/or surgery may be recommended in addition to chemotherapy.
No standard of care has been established for large cell neuroendocrine carcinoma, which is very uncommon. Depending on the stage of the tumor, adjuvant chemotherapy may be recommended for select patients following surgical removal of a large cell neuroendocrine tumor. Chemotherapy also may be recommended if the tumor has spread to other organs. Generally, patients with large cell neuroendocrine carcinoma are treated with chemotherapy regimens used to treat small cell lung cancer.


text:
You purchased this item onView this order
Jarrow Formulas, Green Tea, Decaffeinated, 500 mg, 100 Capsules (Discontinued Item)
- You earn loyalty credit for every order you place at iHerb!
- Loyalty credit is equal to 10% of the value of your order, excluding shipping charges.
- Your loyalty credit will be applied towards your next order as soon as your current order has shipped.
- Your loyalty credits are valid for up to 60 days from the date of your last purchase.
Shipping Weight:?0.24 lbs (0.11 kg)Shipping WeightThe Shipping Weight includes the product, protective packaging material and the actual shipping box. In addition, the Shipping Weight may be adjusted for the Dimensional Weight (e.g. length, width & height) of a package. It is important to note that certain types of products (e.g. glass containers, liquids, fragile, refrigerated or ice packed) will often require protective packaging material. As such, these products will reflect a higher Shipping Weight compared to the unprotected product.
- Product Code: JRW-17023
- UPC Code: 790011170235
- Package Quantity: 100 Capsules
- Dimensions: 2.4 x 2.4 x 4.3 in, 0.2 lbs (0.09 kg)
- Decaffeinated by Water Extraction
- Antioxidant Protection
- Supports Cardiovascular and Immune Health
- Dietary Supplement
- Vegan
- Non GMO (Non Genetically Modified)
- Suitable for Vegetarians/Vegans
Jarrow Formulas Green Tea Decaffeinated is water extracted and decaffeinated, consisting of 50% polyphenols, including 30% catechins, approximately 15% of which is the important EGCG fraction. The polyphenols in green tea are potent antioxidants and support cardiovascular and immune health.
Suggested Use
Take 1 capsules per day with food or as directed by your qualified healthcare professional.
Other Ingredients
Cellulose, magnesium stearate (vegetable source) and silicon dioxide. Capsule consists of hydroxypropylmethylcellulose.
No wheat, no gluten, no soybeans, no dairy, no egg, no fish/shellfish, no peanuts/tree nuts.
If you have a medical condition, are pregnant, lactating, trying to conceive, or taking medications, consult your healthcare professional before using this product.
Store in a cool, dry place.
Keep out of the reach of children.
|Supplement Facts
|Serving Size: 1 Capsule
|Servings Per Container: 100
|Amount Per Serving
|Green Tea, water extract
(Camelia sinensis) (leaf)
Decaffeinated, 50% polyphenols (30% catechins)
|500 mg
|* Daily Value not established.
|Jarrow Formulas Green Tea Decaffeinated contains the following approximate profile of antioxidants:
|Total Polyphenols
|EGCG (Epigallocatechingallate)
Unlike some green tea tablets I purchased earlier, these are easy to swallow. No jitters.
If I don`t have time to make the tea, just pop in. This really does make you less hungry and if you take the cinnamon vegee caps or just from your spice rack that helps too.
Havent used enough
Posted by 5423242942990293316 on Jan 08, 2013
I am not sure how well this works. I wanted to review one item, not all.
Good product
Posted by Reviewer3306205 on Nov 20, 2012
Great price too. Will continue to buy
This is great stuff...
Posted by Reviewer2583260 on Mar 12, 2012
If I don`t have time to make the tea, just pop in. This really does make you less hungry and if you take the cinnamon vegee caps or just from your spice rack that helps too.
works for me!
Posted by Reviewer1190904 on Feb 02, 2012
seems to be working
Great product
Posted by Reviewer1545543 on Aug 07, 2011
Good antioxidant.


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Team USA, Canada and the Iroquois are the clear top dogs in the FIL World Championships. But each team has its own set of questions and decisions to be made. The IL asked the biggest ones heading into the tournament. First up: Team USA. Catch USA vs. Canada on ESPN2, 9 p.m. ET (7 p.m. MT) Thursday to kick off the games. Inside Lacrosse is in Denver ready to go; follow us on Instagram @IL_Photos and Twitter @Inside_Lacrosse.
Find USA and the Blue Division rosters here.
Will the U.S. play a more dynamic style?
Adapting to the International Rules is tough on everybody, but the U.S. looked particularly plodding in their tune-up with the MLL All-Stars in Boston earlier this month (save some dramatics from eventual team U.S. selectee Rob Pannell). The U.S. have the horses to run an up-tempo style, but the rules favor more deliberate action. I expect to see more full-field action and scoring moving forward.
Who'll take the ball away if the U.S. is down two goals with four minutes to go?
Stalling is more common and accepted in international play than in some of the game's other incarnations, and because of the rules about going below GLE, most of the stalling occurs around the midline. That means that if the U.S. needs to press out and cause a turnover late in a game, they'll most likely have to rely on longpoles Jesse Bernhardt and Kyle Hartzell. That's not a bad ask, but it is Brian Karalunas' specialty and one of the main assets they lost by not carrying him from the 30-man cutdown roster.


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Baby Name Poll Results
Danica vs. Isabelle vs. Olivia
Please help us choose a name for our baby girl, she's due at the beginning of March. Please vote and leave comments, we also need suggestions for middle names!!
The Top Baby Name is...
|24% (6 votes)
|52% (13 votes)
|24% (6 votes)
Danica (Dani) is adorable. My second fave is Isabelle (Belle).
posted by guest :: 2008-02-10 00:08:21 | report
Isabelle Grace
Isabelle Bree
Isabelle Ashley
Isabelle Florence
Isabelle Caitlin
Isabelle Joy
Isabelle Alexa
Isabelle Harper
Isabelle Bree
Isabelle Ashley
Isabelle Florence
Isabelle Caitlin
Isabelle Joy
Isabelle Alexa
Isabelle Harper
posted by guest: Marley D :: 2008-02-10 00:09:21 | report
Danica Natalia
posted by guest: M :: 2008-02-10 00:13:18 | report
Isabelle/a has such beautiful unique nicknames: Isa (ee-suh), Izzy, Belle, Bella, Elle, Ella. Love it!
posted by guest :: 2008-02-10 00:18:26 | report
posted by guest :: 2008-02-10 01:13:03 | report
Olivia is beautiful! Olivia Rose sounds lovely paired together. I like the classics. I think Olivia would age better than Danica. Isabella is very overused.
posted by guest :: 2008-02-10 02:08:28 | report
My favorite is Olivia but I also like Isabelle though I prefer the spelling Isobel. Isobel Olivia would be pretty.
posted by guest :: 2008-02-10 09:36:24 | report
Danica nn Nica
posted by guest :: 2008-02-11 19:29:56 | report
Post a Comment:Please keep your comments positive and helpful.
Even if you don't like the names. Thanks!
For all baby name poll questions, complaints, or improvements
contact firstname.lastname@example.com.


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Piper Frameless Mirrors
- Overview
Beveled edges accentuate the graceful shapes of our frameless mirrors. Hang them from the included chains for a vintage look, or remove the chains for a simpler effect.
- Crafted of glass and iron.
- Mirrors are beveled.
- Mounting hardware included.
- Dimensions & Care
- Small: 22" wide x 20" high
- Small weight: 6 pounds
- Medium: 21" wide x 26" high
- Medium weight: 7.5 pounds
- Large: 32" wide x 22" high
- Large weight: 11.5 pounds
- Clean glass with standard glass cleaner.
- Wipe frame with a soft clean cloth.
- Shipping & Return Info
This is a general shipping item.
Shipping Information
Hassle Free Returns
To make this gift-giving season a little merrier, we are extending our Returns & Exchange Policy. For all items purchased between Oct. 21 and Dec. 24, 2016, you'll have until January 31, 2017 to return the item for a refund of the merchandise value. Just make sure to bring your proof of purchase or gift receipt. Quick Ship upholstery items are excluded from the Extended Holiday Return Policy. You have 7 days to return your Quick Ship upholstery item for a full refund or exchange.
The following items are non-eligible for returns or exchanges:
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- Items damaged through normal wear and tear.
Delivery fees are non-refundable and prior purchases are not eligible for price adjustments.
For more information, view our full Returns & Exchange Policy.


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Coconut revival talks in Samoa
An in depth review of the Coconut industry in the Pacific is under way at Hotel Tanoa Tusitala in Apia. The talks are looking to develop feasible research and strategies to resolve issues that prohibit the growth of the industry.
The 'Pacific Coconut Research and Development Strategy' Meeting is being hosted by the Secretariat of the Pacific Community (SPC) and the Australian Centre for International Agricultural Research (ACIAR).
Held over three days,the conference is being attended by policy makers, senior government officials, researchers, development agents, coconut product manufacturers, exporters and buyers from around the Pacific region.
Coconut Agronomist at the Ministry of Agriculture and Fisheries, Fata Alo Fania, said the main issue for Samoa is the age and productivity of the coconut trees.
"The coconut trees in Samoa are very old," he said."So we need to replace those old trees by planting new ones…we need to find which coconut trees have the most potential to be productive."
To address this, two islands –Namu'a in Aleipata and Nu'usafee in Faleali -have been selected to be used as nurseries for new coconut trees.Namu'a and Nu'usafee have been chosen for their isolation, since it is harder to conserve coconut trees on the mainland, Fata said.
The hybrid coconut especially, is in high demand for its good oil content, ability to grow well in Samoa, and productivity.
Dr. Mike Foale, from the School of Agriculture and Food Sciences in Australia, has been researching coconut for fifty years. He saidplans to revive the coconut are an exciting and important prospect.
Dr. Foale is developing a new product called Hot Oil dried desiccated coconut, which can be used as a substitute for flour, in cooking and baking and in desserts.
Speaking to the Samoa Observer, he believes the best future developments are to have more high value products such as virgin coconut oil.
"Virgin oil has made a big impact and I think there's potential for other products based on the coconut kernel – big products," he said."I believe the coconut industry can really prosper and bring in much better income for coconut producers by marketing high value products such as virgin oil."
Kitiona Salanoa, owner of 'Mailelani',knows the importance of improving coconut productivity since his business uses large quantities to make soaps and lotions.


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Thio, Chloe L.a; Smeaton, Laurab; Saulynas, Melissaa; Hwang, Hyona; Saravan, Shanmugamc; Kulkarni, Smitad; Hakim, Jamese; Nyirenda, Mulindaf; Iqbal, Hussain S.c; Lalloo, Umesh G.g; Mehta, Anand S.h; Hollabaugh, Kimberlyb; Campbell, Thomas B.i; Lockman, Shahinj; Currier, Judith S.k
In this paper [1], last name of a co-author should read Saravanan instead of Saravan. Therefore, his full name should read 'ShanmugamSaravanan'.
March 27, 2013.
aJohns Hopkins University, Baltimore, Maryland
bHarvard School of Public Health, Boston, Massachusetts, USA
cYRG Centre for AIDS Research and Education, Voluntary Health Services Hospital Campus, Taramani, Chennai
dNational AIDS Research Institute-ICMR, Pune, India
eCollege of Health Sciences, University of Zimbabwe Clinical Research Centre, Harare, Zimbabwe
fJohns Hopkins Research Project, Department of Medicine, College of Medicine, Blantyre, Malawi
gNelson R Mandela School of Medicine, University of KwaZulu-Natal, Glenwood, South Africa
hDrexel University College of Medicine, Philadelphia, Pennsylvania
iUniversity Of Colorado School Of Medicine, Aurora, Colorado
jBrigham and Women's Hospital and Harvard School of Public Health, Boston, Massachusetts
kUCLA David Geffen School of Medicine, Los Angeles, California, USA.
Correspondence to Chloe L. Thio, MD, Associate Professor of Medicine, Johns Hopkins University, 855 N Wolfe Street, 5th floor, Baltimore, MD 21205, USA. Tel: +1 410 614 6088; e-mail: email@example.com
Received 10 August, 2012
Revised 6 September, 2012
Accepted 20 September, 2012
Objective: To understand the HIV–hepatitis B virus (HBV) epidemic from a global perspective by clinically and virologically characterizing these viruses at the time of antiretroviral therapy (ART) initiation in a multinational cohort.
Methods and design: HIV-infected patients enrolled in two international studies were classified as HIV–HBV coinfected or HIV monoinfected prior to ART. HIV–HBV coinfected patients were tested for HBV characteristics, hepatitis D virus (HDV), a novel noninvasive marker of liver disease, and drug-resistant HBV. Comparisons between discrete covariates used χ2 or Fisher's exact tests (and Jonchkheere–Terpstra for trend tests), whereas continuous covariates were compared using Wilcoxon Rank-Sum Test.
Results: Of the 2105 HIV-infected patients from 11 countries, the median age was 34 years and 63% were black. The 115 HIV–HBV coinfected patients had significantly higher alanine aminotransferase and aspartate aminotransferase values, lower BMI, and lower CD4+ T-cell counts than HIV monoinfected patients (median 159 and 137 cells/μl, respectively, P = 0.04). In the coinfected patients, 49.6% had HBeAg-negative HBV, 60.2% had genotype A HBV, and 13% were HDV positive. Of the HBeAg-negative patients, 66% had HBV DNA 2000 IU/ml or less compared to 5.2% of the HBeAg-positive individuals. Drug-resistant HBV was not detected.
Conclusion: Screening for HBV in HIV-infected patients in resource-limited settings is important because it is associated with lower CD4+ T-cell counts. In settings in which HBV DNA is not available, HBeAg may be useful to assess the need for HBV treatment. Screening for drug-resistant HBV is not needed prior to starting ART in settings in which this study was conducted.
Chronic hepatitis B (CH-B), which is the leading cause of end-stage liver disease worldwide, is common in HIV type-1-infected individuals with a prevalence ranging from 5 to 20% in various studies of HIV-infected patients [1–5]. Although coinfection with HIV and hepatitis B virus (HBV) is recognized as being common, there are limited data to provide an international perspective on this epidemic. Such a perspective is especially important as HAART is being introduced worldwide including in resource-limited settings with high HBV endemicity such as Asia and Africa. Because liver disease is a leading cause of non-AIDS death in HIV-infected patients receiving HAART, characterizing HBV prior to HAART is important in order to better understand the scope of the disease and to prioritize treatment needs in resource-limited settings.
Most studies of HIV–HBV coinfected patients have been conducted in countries with low HBV endemicity and have shown a negative effect of HIV on CH-B with decreased hepatitis B e antigen (HBeAg) clearance, high HBV DNA levels, and increased risk for cirrhosis and liver-related death [6,7]. Data from countries with low HBV endemicity are informative, but they represent HBV disease that occurs primarily in adulthood. In contrast, in countries with high HBV endemicity, transmission primarily occurs in infancy or early childhood; thus, in most of these cases, HBV has been present for years prior to HIV infection. It is not known if the worldwide epidemic is similar to what has been reported from countries with low HBV endemicity. One study from Nigeria suggests that this may not be the case because HBV DNA levels were lower than what has been seen in studies from North America and Europe [8]. Thus, data on HIV and HBV characteristics with a more global perspective in these coinfected individuals at the time HAART is initiated are needed.
Two randomized clinical trials of antiretroviral therapy were conducted by the Adult AIDS Clinical Trials Group (ACTG) in diverse resource-limited settings. The first, ACTG A5175, enrolled HIV-infected men and women worldwide to compare different initial HAART regimens [9]. The second, A5208, compared the response of first-line HAART in African women who had received single-dose nevirapine during a prior pregnancy to those who had not received nevirapine [10]. Both of these trials tested individuals for HBV at HAART initiation; thus, they are useful to characterize untreated HIV and HBV coinfection from a multinational perspective.
The participants were enrolled in one of the following parent ACTG studies: A5175 or A5208. A5175 was a randomized, open-label comparison of once-daily protease inhibitor or nonnucleoside reverse transcriptase inhibitor-containing regimens for HAART-naive HIV-infected men and women [with CD4+ T-cell count <300 cells/μl and alanine aminotransferase (ALT)/aspartate aminotransferase (AST) <5 × upper limit of normal (ULN)] from Brazil, Haiti, India, Malawi, Peru, South Africa, Thailand, United States, and Zimbabwe, as previously described (n = 1571) [9]. A5208 studied the response to a nevirapine-based initial HAART regimen after peripartum exposure to single-dose nevirapine (n = 745). Women in A5208 had CD4+ T-cell count less than 200 cells/μl, baseline AST/ALT less than 2.5 × the ULN, and came from one of the following African countries: South Africa, Kenya, Zimbabwe, Botswana, Zambia, Malawi, and Uganda, as previously described [10]. All A5175 sites and seven of the 10 A5208 sites received local Institutional Review Board approval for participation in this study. Informed consent was obtained from the study participants in their native language, and the study was also approved by the Johns Hopkins University IRB. Of the sites that participated, Brazil excluded people who had CH-B from enrolling in the parent study; thus, Brazilian participants were not included in prevalence estimates but are included in the HIV monoinfected study group. In addition, four of the 25 US sites, which enrolled 13% of the individuals from the United States, excluded people with CH-B.
Participants were classified as HIV–HBV coinfected if they were hepatitis B surface antigen (HBsAg) positive at the visit prior to randomization and positive for HBeAg, HBV DNA, or hepatitis B e antibody (anti-HBe) at the study entry visit. All others were classified as HIV monoinfected. Data abstracted from the parent study database included the following criteria: age, sex, race, BMI, history of liver disease, hemoglobin, HIV disease stage, HIV RNA, CD4+ T-cell count, ALT, and AST. The HIV–HBV coinfected participants also had the following performed using study entry visit serum: HBeAg, anti-HBe, HBV genotype, HBV DNA, hepatitis D antibody [anti-hepatitis D virus (anti-HDV)], hepatitis C virus (HCV) antibody (anti-HCV), HCV RNA if anti-HCV positive, HBV Pol sequencing, and a noninvasive marker of liver disease that correlates with liver disease [11]. This noninvasive marker measures the change in glycosylation of an immunoglobulin G reactive to a specific α-galactose epitope, which is measured by reactivity to the fucose-binding lectin aleuria aurantia lectin (AAL-reactivity). This marker was selected because other readily available markers use parameters such as platelets that are affected by HIV infection.
All specimens were stored at −80°C. Serological testing for HBeAg (ETI-EBK Plus; Diasorin, Stillwater Minnesota, USA or Abbott ARCHITECT HBeAg v17.0, Abbott Park, Illinois, USA), anti-HBe (ETI-AB-EBK Plus or Abbott ARCHITECT Anti HBe v13.0), anti-HDV (ETI-AB-DELTAK-2; Diasorin, Stillwater, Minnesota, USA), and anti-HCV (Ortho HCV v3.0; Ortho Diagnostics, Raritan, New Jersey, USA) were performed according to manufacturer's instructions. HBV DNA testing was done with real-time PCR using either RealART HBV LC PCR v 3.0 (Qiagen, Valencia, California, USA) or Abbott RealTime HBV DNA (Abbott Molecular, Des Plains, Illinois, USA). The highest common lower limit of detection of these assays was 200 IU/ml, which is the value used in the analyses. HBV genotype and drug-resistance mutations were determined by HBV Pol sequencing, performed as previously described [12]. HCV RNA was determined with the Abbott RealTime HCV RNA (Abbott Molecular) performed according to manufacturer's instructions. AAL-reactivity was tested as previously described [11] with values greater than 5 representing cirrhosis, values 3–5 representing moderate liver disease, and values of 1–2 representing no or mild liver disease.
ALT and AST levels were graded according to standard ACTG definitions [13]. Comparisons between groups were made using χ2 or Fisher's exact test for discrete covariates and Wilcoxon Rank-Sum Test for continuous covariates. For three-level ordinal group comparisons, the Jonchkheere–Terpstra trend test was performed. To test for associations of pretreatment covariates with baseline HBV DNA level, linear regression modeling on the log10 transformed HBV DNA was performed. Pretreatment covariates tested include screening CD4 T-cell count category (<50, 50–199, and 200–299), log10 HIV-1 RNA copies/ml, sex, age, BMI, anti-HDV, HBeAg, anti-HBe, HBV genotype, hemoglobin per 5 g/dl increase, creatinine clearance (Cockcroft–Gault equation), ALT, and AST. P values less than 0.05 were considered statistically significant and were not adjusted for multiplicity.
A5175 and A5208 recruited 2316 participants of whom 2105 (90.9%) were enrolled in sites that obtained IRB approval for this substudy. Of these 2105 participants, 115 (5.5%) were HIV–HBV coinfected. There was no significant difference in the prevalence of a positive HBsAg between the sites that did (6.7%) and did not (5.6%) have IRB approval for this substudy. The HIV–HBV coinfection prevalence varied with the highest prevalence in Zimbabwe (11%) and the lowest in Kenya (2.2%) (Table 1). The prevalence of HIV–HBV coinfection across continents was similar with Asia at 5.9%, Africa at 6.7%, Central/South America at 5.1% (excluding Brazil), and North America (United States) at 4.8%. Anti-HCV was positive in six participants who all had undetectable HCV RNA.
The median age of the 2105 participants was 34 years and 39% were men (Table 2). The racial make-up was majority black (62.7%) followed by Asian (17%), white (11.9%), and other (7.4%). The HIV–HBV coinfected participants had more blacks and fewer whites than the HIV monoinfected individuals (P = 0.07). The BMIs were lower among the HIV–HBV coinfected (median 21.7) compared to the HIV monoinfected participants (median 22.4, P = 0.02); however, the distribution of numbers in each BMI category (underweight, normal, overweight, and obese) was similar.
Given the entry criteria for the parent studies, only seven individuals had grade 3 and 4 elevations of ALT or AST, all of whom were HIV monoinfected. Although ALT and AST values were typically low (median 23 and 29 U/l, respectively), the distributions of these values were both higher among the HIV–HBV coinfected (median ALT 25.5 U/l, median AST 34 U/l) compared to the HIV monoinfected individuals [median ALT 23 U/l (P = 0.03), median AST 28.8 U/l (P < 0.001)] (Table 2).
The median CD4 T-cell count was 157 cells/μl [interquartile range (IQR) 88–218 cells/μl] and was significantly lower in the HIV–HBV coinfected (137 cells/μl, IQR 68–210 cells/μl) than in the HIV monoinfected individuals [159 cells/μl (IQR 90–218 cells/μl, P = 0.04] (Table 2). However, the two groups did not differ in HIV RNA level (median 5.10 and 5.05 log10 copies/ml, respectively, P = 0.23). Also, the CD4 T-cell differences between the groups could not be accounted for by differences in HBV prevalence by country (Fig. 1). Consistent with the difference in CD4 T-cell counts, the HIV–HBV coinfected patients had a higher prevalence of clinical AIDS, which was defined as WHO stage IV or history of AIDS, but the difference was not statistically significant (12.2 versus 8.6% in HIV–HBV coinfected and HIV monoinfected, respectively, P = 0.19).
As a sensitivity analysis, we repeated the above analyses excluding participants from Brazil because they were all HIV monoinfected by that site's inclusion criteria. Comparisons between HIV monoinfected and HIV–HBV coinfected participants were similar with the following exceptions. The proportion of men was significantly higher in the HIV–HBV coinfected (46%) compared to the HIV monoinfected group (36%, P = 0.02). The difference in the distribution of races between groups was attenuated (P = 0.7). However, the difference in the ALT distribution between groups was strengthened (P = 0.002).
From the study entry visit, serum was available for additional HBV testing in the 113 of the 115 HIV–HBV coinfected patients. Approximately, half, 57 of 113 (50.4%), were HBeAg-positive, and this proportion was similar in A5175 (51.8%) and A5208 (46.7%). The median age was 34 years in both the HBeAg-negative and HBeAg-positive individuals and the proportion of women was similar between the HBeAg groups (48 and 52%). By country, participants from Haiti (83%), India (69%), Kenya (67%), and Peru (83%) were predominantly HBeAg-positive, whereas those from Malawi (65%), Thailand (63%), and the United States (80%) were mainly HBeAg negative.
HBV genotype could not be determined for 18 (16%) participants due to low HBV DNA. Among observed genotypes, the most common were A (71.5%) and D (15.8%), but the distribution varied geographically with Africa having 95% genotype A, US with 78% genotype A, Thailand and India with 100% genotype C and D, respectively, and South and Central America with 55% genotype A, 27% genotype F, and 18% genotype E. Genotypes A and C were evenly divided between HBeAg-positive and HBeAg-negative disease, whereas D, E, and F were predominantly in HBeAg-positive participants (Table 3).
Anti-HDV was detected in 15 of 113 (13.3%) HBV coinfected participants, which is within the range of the prevalence reported in HBV monoinfection [14]. Anti-HDV was detected only among participants from Botswana, Kenya, Peru, South Africa, Thailand, or Zimbabwe, with Botswana having the highest relative number of participants (three of four). When stratified by HBeAg status, a similar proportion of the HBeAg-negative and HBeAg-positive participants (14 and 12%, respectively) were anti-HDV positive.
HBV DNA was detected in 91.2% of the 113 coinfected patients and was significantly more common in the HBeAg-positive (98.2%) compared to the HBeAg-negative patients (83.9%, P = 0.008) (Table 3). The median HBV DNA was significantly higher in the HBeAg-positive (median 7.96 log IU/ml) compared to the HBeAg-negative patients (median 2.74 log IU/ml, P < 0.001). In fact, 66.1% of HBeAg-negative patients had an HBV DNA 2000 IU/ml or less, which is the level above which treatment should be considered in HBeAg-negative patients [15]. In contrast, only 5.2% of HBeAg-positive patients had HBV DNA 2000 IU/ml or less. Only 12% of the HBeAg-positive patients had values below the cutoff recommended by some treatment guidelines for HBeAg-positive monoinfected patients (20 000 IU/ml) [15]. Genotypes C, D, and F had a higher proportion of participants with HBV DNA greater than 20 000 IU/ml compared to the other genotypes (P = 0.049).
In univariable analysis with log HBV DNA as the outcome, HBeAg-positive patients had a 3.63 log IU/ml [95% confidence interval (CI) 2.95–4.32 log IU/ml] higher HBV DNA than those who were HBeAg-negative (P < 0.01) (Fig. 2a). Those with higher ALT and AST also had higher log HBV DNA values. When compared to patients infected with genotype A, those infected with genotype D had a 1.61 log IU/ml higher HBV DNA (95% CI 0.21–3.01 log IU/ml) and those infected with genotypes C, E, or F had a 1.37 log IU/ml higher HBV DNA (95% CI −0.17 to 2.91 log IU/ml). In a multivariable model, only HBeAg status and AST remained significantly associated with higher HBV DNA (Fig. 2b).
Of the 95 individuals with HBV Pol sequencing, none (95% CI 0–3.7%) had mutations in HBV Pol that are associated with known resistance to lamivudine, adefovir dipivoxil, or entecavir [16].
AST values were higher in the HBeAg-positive (median 36.0 U/l) compared to the HBeAg-negative patients (median 31.5 U/l, P = 0.008) with a similar relationship in ALT (median 28.0 and 23.0 U/l, respectively, P = 0.03) (Table 3). Liver disease was measured by AAL-reactivity in 103 individuals because the samples from India were not available for this assay. No or mild liver disease was present in 39 (37.8%), moderate liver disease in 48 (46.6%), and cirrhosis in 16 participants (15.5%). All 16 with cirrhosis were from A5175, 15 of whom were black. The 16 with AAL values consistent with cirrhosis (>5) trended toward a lower albumin (3.29 g/dl) compared to the 87 without cirrhosis (3.62 g/dl)(P = 0.06); however, none of these 16 participants had clinical signs or symptoms of liver disease.
Because the HIV–HBV coinfected patients had lower CD4+ T-cell counts than the HIV monoinfected patients, we further explored the relationship between HBV DNA and CD4+ T-cell counts among the coinfected patients. The median CD4+ T-cell count did not differ by HBeAg status. To determine if CD4+ T-cell count was associated with HBV DNA, the CD4+ T-cell count was stratified into three groups of less than 50, 51–199, and more than 200 cells/μl. The proportion of patients with HBV DNA more than 200 000 IU/ml decreased significantly as CD4+ T-cell count increased (P = 0.04) (Fig. 3).
This is the first multinational study of HIV–HBV coinfected individuals characterizing both HBV and HIV parameters at the time of HAART initiation. Several notable findings include an association between HBV coinfection and lower CD4+ T-cell count especially those with high HBV DNA levels, the low HBV DNA levels in the majority of HBeAg-negative patients, and the absence of drug-resistant HBV. Such characterization of HBV in HIV-infected patients at the time of HAART initiation advances our understanding of HBV in this setting in order to focus treatment efforts.
The association of lower CD4+ T-cell counts with HIV–HBV coinfection was first noted in a Nigerian study, but it was not clear if that finding was universal or specific to Nigeria [8]. This is the first multinational study demonstrating that HIV–HBV coinfected patients have lower CD4+ T-cell counts than HIV monoinfected patients. If the findings were region-specific, then the association would have been diminished with the diverse countries included in this study. This finding is also robust because it was detected despite the fact that study entry criteria for the parent studies required a CD4+ T-cell count less than 300 cells/μl (for A5175) or 200 cells/μl (for A5208). Furthermore, this is the first study to demonstrate that the HIV–HBV coinfected patients with CD4+ T-cell counts less than 50 cells/μl were more likely to have high levels of HBV replication (HBV DNA >200 000 IU/ml) than were those with higher CD4+ T-cell counts. One possible mechanism for this association is that CH-B may lead to immune activation, which increases CD4+ T-cell apoptosis. This association is not due to differences in geographical distribution of CD4+ T-cell counts among countries because those with higher HBV prevalence did not recruit patients with lower CD4+ T-cell counts.
The low levels of HBV DNA in a large proportion of individuals was unexpected because HIV-HBV coinfection is associated with higher HBV DNA in patients from areas of the world with low HBV endemicity [6]. In our study, 16% of the HBeAg-negative patents had an undetectable HBV DNA, and an additional 50% had a HBV DNA less than 2000 IU/ml, which is the level above which treatment is considered. In contrast, the majority of HBeAg-positive patients (75%) had detectable HBV DNA levels that were more than 200 000 IU/ml. These findings are supported by the multivariable analysis demonstrating that HBeAg-positive status was the only factor associated with higher HBV DNA levels. The low HBV DNA in this cohort is not simply due to exclusion of patients with higher ALT or AST levels, as studies from Nigeria and South Africa that did not exclude such patients also show low HBV DNA in a substantial proportion of HIV–HBV coinfected patients [8,17]. In the Nigerian study, these low levels were also found primarily in HBeAg-negative patients, but HBeAg was not determined in the other study. Taken together, these studies suggest that determining HBeAg may provide a strategy to prioritize the need for HBV treatment in HIV-infected individuals when HBV DNA assays are not available in resource-limited settings.
In our study, no participant had pre-existing drug-resistant mutations in the majority population of the quasispecies. In two prior Japanese studies of therapy-naive individuals, the prevalence of drug-resistant mutants using population sequencing was 0 and 1.6% [18,19]. One of these studies used a second assay that could detect as little as 0.001% of mutant virus and found that 11% of patients had a drug-resistant virus in the minority population [18]. However, whether such low levels of virus lead to HBV treatment failure is not known. One study found lamivudine-resistant strains in 10 of 20 HIV–HBV coinfected patients prior to therapy, but the pattern of mutations was identical in the majority of the tested samples suggesting that contamination may explain this high prevalence [20]. Our study does not support the need for HBV drug-resistance testing prior to starting anti-HBV therapy.
Our study had several limitations. First, the inclusion criteria of the parent antiretroviral treatment trials may have skewed our study population. Even though both parent studies were focused on participants with CD4 T-cell counts less than 300 cells/μl, we were still able to see an association between CD4 T-cell count and HBV infection. The exclusion of patients with very high AST and ALT may have underestimated the prevalence of CH-B, especially in those with HBeAg-positive disease. However, we believe that this exclusion did not substantially alter the HBV DNA findings or the association with lower CD4+ T-cell counts, as discussed above. In addition, HIV–HBV coinfected patients are recognized to have lower ALT levels than are HBV monoinfected patients despite higher HBV DNA levels [6]. Second, we were not able to characterize liver disease using a liver biopsy because biopsies were not feasible and are not readily available in resource-limited countries. However, we did use a noninvasive marker of liver disease (AAL reactivity) that correlates with the level of fibrosis [11] and does not use platelet count, which can be affected by HIV. About 15% of the cohort had a level of AAL reactivity that was consistent with cirrhosis, which was almost exclusively found in individuals of African descent; however, the only sign of liver disease in these individuals was a trend toward lower albumin. This prevalence is similar to that described in HBV monoinfected cohorts with ALT cutoffs that were less than 2 × the ULN [21]. A Ugandan study found a 17% prevalence of significant fibrosis in HIV monoinfected patients [22]; thus, the cirrhosis prevalence in our study of HIV–HBV coinfected individuals is possible. Further studies are needed to characterize liver disease in HIV–HBV coinfected patients from resource-limited settings including those with high ALT/AST levels. Third, we did not find an association in the multivariable analysis with HBV genotype and HBV DNA, but these data are limited by the inability to genotype 16% of the individuals. This lack of association was also seen in a study from Denmark of 784 HBV monoinfected patients [23]. However, in another study, HBV DNA levels were the highest in HBeAg-positive patients with HBV genotype D [24].
In summary, we found a variable prevalence (2–11%) of hepatitis B in HIV-infected patients from diverse settings prior to starting HAART. Thus, it is important for providers to know the prevalence of HBV in their country. HBV DNA levels were relatively low in HBeAg-negative patients; thus, this serologic marker may be useful in prioritizing patients on their need for HBV treatment in settings in which HBV DNA is not available. HIV–HBV coinfection, especially those with high HBV DNA, was associated with lower CD4+ T-cell counts prior to HAART initiation, which emphasizes the need for HBV testing in HIV-infected patients. Further work is needed to study HIV–HBV coinfection in patients with high ALT/AST levels, to understand the mechanism for CD4+ T-cell loss in HIV–HBV coinfection, and to optimize treatment for HIV–HBV coinfection in resource-limited settings.
The authors would like to acknowledge the efforts of the investigators at each of the sites participating in this study, Ken Braun and James Tutko for managing the database, and the A5175 and A5208 study participants.
Study design was conducted by C.L.T., J.H., M.N., U.G.L., S.L., T.B.C., J.S.C.; data analysis was conducted by C.L.T., L.S., K.H., J.S.C.; data collection was performed by M.S., H.S., S.S., S.K., H.S.I., A.S.M.; drafting of manuscript was performed by C.L.T., L.S., K.H., J.S.C.; critical reading of manuscript was done by all the authors.
The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute of Allergy and Infectious Diseases or the National Institutes of Health.
This work received funding support from the National Institute of Allergy and Infectious Diseases at the National Institutes of Health [R01 AI071820 (C.L.T.), K24 AI56933 (J.S.C.), AI068636 (AIDS Clinical Trials Group), AI69450 (T.B.C.), U01 AI068634 (Statistical and Data Management Center of the AIDS Clinical Trials Group), R01CA120206 (A.S.M.), R01CA136607 (A.S.M.)]. It was also supported by Award Number U01AI068636 from the National Institute of Allergy and Infectious Diseases, the National Institute of Mental Health (NIMH), and the National Institute of Dental and Craniofacial Research (NIDCR).
Study drugs were provided by Abbott Laboratories, Boehringer Ingelheim Pharmaceuticals, Gilead Sciences, Bristol-Myers Squibb, GlaxoSmithKline, and Merck & Co. Inc.
Additional funding for each site includes:
UZ-Parirenyatwa CRS (Site 30313) CTU Grant: 1U01AI069436-01
Wits HIV CRS (Site 11101) CTU Grant: 1U01AI069463-01
University of North Carolina Project, Kamuzu Central Hospital (Site 12001) CTU Grant: 1U01AI069518-01
Durban Adult HIV CRS (Site 11201) CTU Grant: 1U01AI069426-01
YRG CARE Medical Ctr., VHS CRS (Site 11701) CTU Grant: 1U01AI069432-01
Instituto de Pesquisa Clinica Evandro Chagas CRS (Site 12101) CTU Grant: 1U01AI069476-01
College of Med. JHU CRS (Site 30301) CTU Grant: 1U01AI069518-01
Chiang Mai Univ. ACTG CRS (Site 11501) CTU Grant: 1U01AI069399-01
Hospital Nossa Senhora da Conceicao CRS (Site 12201) CTU Grant: 1U01AI069401-01
Les Centres GHESKIO CRS (Site 30022) CTU Grant: 1U01AI069421-01
NARI Pune CRS (Site 11601) CTU Grant: 1U01AI069417-01
Asociacion Civil Impacta Salud y Educacion, Sede Barranco(Site 11301) CTU Grant: 5U01 AI069438
Walter Reed Project – Kenya Med. Research Institute (Site 12501) CTU Grant: IAA#Y1-AI-8374-01
AMPATH at MOI Univ. Teaching Hosp. Eldoret CRS (Site 12601) CTU Grant: IAA#Y1-AI-8374-01
Kalingalinga Clinic CRS (Site 12801) CTU Grant: 1U01AI069518-01
Gaborone Prevention/Treatment Trials CRS (Site 12701) CTU Grant: 1U01AI069456-01
(Site 12401) CTU Grant: 1U01AI069456-01
San Miguel CRS (Site 11302) CTU Grant: 5U01AI069438
Molepolole Prevention/Treatment Trials CRS (Site 12702) CTU Grant: 1U01AI069456-01
University of Texas Southwestern Medical Center (Site 3751) Grant: AI 046376
NARI Clinic at NIV CRS (Site 11603) CTU Grant: 1U01AI069417-01
University of Cincinnati (Site 2401) CTU Grant: AI-069513
Univ. of California Davis Med. Ctr., ACTU (Site 3851) Grant: AI38858-09S1
NARI Clinic at Gadikhana Dr Kotnis Municipal Disp (Site 11602) CTU Grant: 1U01AI069417-01
University of Colorado Hospital CRS (Site 6101) CTU Grant: AI69450
The Ohio State University (Site 2301) CTU Grant: AI069474
Northwestern University CRS (Site 2701) CTU Grant: AI069471
University of Minnesota (Site 1501) CTU Grant: AI27661
Washington U CRS CTU (Site 2101) Grant: 1U01AI069495
Beth Israel Med. Ctr., ACTU (Site 2851) CTU Grant: AI46370
The Miriam Hospital (Site 2951) CTU Grant: AI069472-01
Duke University Medical Center CRS (Site 1601) CTU Grant: AI069484-06
University of Southern California CRS (Site 1201) CTU Grant: AI069428
Harbor-UCLA Medical Center (Site 603) CTU Grant: U01-A1 069424
UNC AIDS CRS (Site 3201) CTU Grant: AI069423; RR 025747; AI050410
Hospital of the University of Pennsylvania CRS (Site 6201) CTU Grant: U01-AI-AI69467-05; CFAR Grant: P30-AI-045008-12
HIV Prevention & Treatment CRS (Site 30329) CTU Grant: 1U01AI069470
Vanderbilt Therapeutics CRS (Site 3652) CTU Grant: U01-AI069439
Rush Univ. Med. Ctr. ACTG CRS (Site 2702) CTU Grant: 1U01AI069471-01
University of Texas, Galveston (Site 6301) Grant: AI32782
New York University/NYC HHC at Bellevue Hospital (Site 401) CTU Grant: Al-27665; Al069532
Christine Hurley, RN and Roberto Corales, DO-AIDS Care CRS (Site 1108) CTU Grant: U01AI069511-02 (as of 2/12/08); CTSI: UL1 RR 024160
UCLA CARE Center CRS (Site 0601) CTU Grant: 1U01AI069424-01
University of Rochester (Site 1101) CTU Grant: U01AI069511-02 (as of 2/12/08); CRC: UL1 RR 024160
Cook County Hospital CORE Center (Site 2705) CTU Grant:1U01AI069471-01
SSTAR, Family Healthcare Center (Site 2954) Grant: AI46381
Wake County Health and Human Services Clinical Research Site (Site 3206) CTU Grant: AI25868
University of Hawaii at Manoa, Leahi Hospital (Site 5201) Grant: AI34853
Todd Stroberg, R.N., and Christina Megill, PA-C. -Cornell CTU (Site 7804) CTU Grant # AI069419 CTSC# RR024996
There are no conflicts of interest.
coinfection; global; hepatitis B virus; HIV
© 2013 Lippincott Williams & Wilkins, Inc.
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The Bold And The Beautiful Weekly Summary For May 14-18.
Botched plans and unexpected turns.
Liam gulped as Steffy and Hope bickered over him. Hope remained clueless about the annulment papers and looked forward to the wedding in Italy. Meanwhile, Stephanie and Brooke bickered about Hope and whether the troubled young woman needed a husband more than mental help. Brooke stormed off to confront Liam about tearing up the papers. She worried that he was getting cold feet about the wedding. She agreed to keep what he did a secret since she could see how worried he was about Hope's inability to deal with reality.
Rick continued to wonder why Caroline seemed so turned off by him. Amber kissed him to cover his lips in lipstick. When he bumped into Caroline, this made things awkward, though he was clueless about it. Amber ran into her and talked about how she's had to come to accept Rick and his habits. Caroline said she had some secrets of her own but couldn't be that open. When Hope arrived, she quizzed Caroline about the situation and she asked her bluntly if she knew Rick was into cross-dressing. Hope thought that was absurd, but Caroline was convinced. Hope ran off to tell Rick about this and chucked the blame at Amber. He confronted Amber and she came clean about her deception. She made excuses but he couldn't forgive her for this as well as giving drugs to Hope.
Ridge was impressed by Thomas' latest designs. Thom said that Caroline was inspiring him. He went off and asked her to dinner. She thought he should come out and meet her parents. When he joined her, Karen and Danielle, he kept wondering where her dad was. Caroline wanted to explain but her mom forbade it. As the dinner party went on, Thomas continuing wondering where Caroline's father was and Bill made some snide remarks. Finally, Caroline got her two moms to admit that they were a couple. Thomas was fine with it but Karen begged him not to tell Bill. When Bill got home, Katie was waiting with big news – she was pregnant. He immediately ordered her to have an abortion.
Make sure to check out our Bold And The Beautiful appearances, B&B news, B&B spoilers and B&B polls. Join us on Twitter @soapoperafan and Facebook. Come tweet and Facebook with us about "Bold And The Beautiful," all the other soap operas, "Dallas," "Glee," "Grey's Anatomy," "Scruples," "Vampire Diaries," and "Venice The Series!"
Photo Credit: Soap Opera Fan Blog
Fun fact! Matthew Purvis wrote this story just for you on May 21st, 2012 |


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How do I solve the following?: du/dt = 2 + 2u + t + tu What I tried:
I multiplied both sides by dt but then I know I have to isolate u but how do I do that?
Any help would be greatly appreciated!
Thanks in advance!
Follow Math Help Forum on Facebook and Google+
so your equation is separable.
Edit: Just something I want to confirm; the book says Ae^(2t + t^2 /2) - 1 where A = e^c
but e^c - 1 is still a constant so I called it K. So is it acceptable to say (instead of what the book says) u = K*e^(2t + t^2 /2) ?
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Arrow S02 BDRip x264-DEMAND
The group DEMAND released BDRip of CW's very popular action,adventure, crime TV Series Arrow's season 02.
4 wins & 16 nominations.
Genre: Action, Adventure, Crime
Synopsis: Spoiled billionaire playboy Oliver Queen is missing and presumed dead when his yacht is lost at sea. He returns five years later a changed man, determined to clean up the city as a hooded vigilante armed with a bow.


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"And we looked like grasshoppers in our own eyes, and so we were in their eyes"
Numbers 13: 33
This week's parashah contains what may be the Bible's only example of meta-empathy. The spies sent to scout out the land of Canaan do not merely put themselves into their enemies' shoes and consider how the world must have looked from their perspective (empathy), but they imagine how they themselves must have appeared to their enemies (meta-empathy): "And we looked like grasshoppers in their eyes."
This act of imagination concludes a report designed to discourage military action: the land devours its settlers, the people are very large, and there are giants there. In that context, empathy in all its forms is problematic; the conquest of the land was the next stage of God's plan for Israel, and the spies were jeopardising the operation. Yet the grasshopper analogy reveals a crucial attribute of the spies, and by extension Israel — their humanity.
The phenomenon of dehumanising the enemy is well-known. Soldiers and civilians alike are encouraged to conceive their enemies as animals as a way of minimising any qualms they might have about killing them. The spies do the very opposite of this. First, they actively identify with their enemies by standing in their shoes and imagining how the world looked from their point of view ("and so we were in their eyes").
Second, far from diminishing the value of their enemies' lives by characterising them as dogs or vermin, they describe themselves as mere insects in relation to their enemies ("and we looked like grasshoppers"). Is this a very early example of awareness that killing must remain complex in a humane society, even at times of war, and even when following a divine imperative? And is it coincidental that the most powerful recent example I can recall — the brilliant Israeli writer Haim Sabato's novel about the Yom Kippur war — has an English title that involves a remarkably similar visual play, Adjusting Sights?


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TransCanada's Keystone XL pipeline would generate more than 5,000 jobs in Nebraska annually during its construction, according to a report commissioned by the Consumer Energy Alliance. The project is also expected to create about $580.2 million in direct spending during construction and another $570.5 million during operation, the report found. "Approving the pipeline is a no-brainer," said Cindy Schild, the American Petroleum Institute's refining senior manager.
Full Story:FuelFix.com


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Ahhh summertime in Ontario: swimming in cool freshwater lakes and streams, fishing off the dock, hiking on endless kilometers of sandy beaches. It's our own Canadian version of paradise, right?
New research suggests that plastic pellets accumulating in our rivers, Great Lakes and shorelines may be turning our pristine playground into a toxic nightmare. Surprisingly, 100 million tons of plastic debris is floating around the world's oceans, but research into the effects of these plastics on our Great Lakes – the largest freshwater ecosystem in the world -- is relatively unchartered territory.
Enter Dr. Patricia Corcoran, Associate Professor in the Department of Earth Sciences at Western University. Dr. Corcoran and her team are conducting pioneering research into the pathways of plastic debris into the Great Lakes, specifically Lake Ontario and Lake Erie. The accumulation of plastics here has the potential for widespread impact on multiple ecosystems, food chains and even tourism.
Corcoran's research concerning plastic debris along Lake Huron was a first for a freshwater ecosystem. Unlike the obvious plastic bottles, syringes and containers that litter our beaches, it's the smaller, meso- and microplastics that have caught her attention, specifically plastic pellets. These lentil-sized plastics are commonly used by manufacturers, melted down and then molded into larger products.
It's a big problem concentrated close to home. Some 47% of the companies in the plastic products industry in Canada are located in Ontario. Pellets are transported around the province, commonly spilling en route to their destinations or on factory floors where they are then swept into drains making their way through our storm sewers and eventually out to the larger bodies of water.
Just how much is getting in, and the effects they are causing, is exactly what Corcoran's research is attempting to uncover. "The first step," says Corcoran, "is to deduce where the hotspots are." Her first significant find is a blob of plastic debris equal to about 25 meters of sidewalk lining the shoreline of Humber Bay. Significant amounts of plastic pellets were also uncovered along the riverbank and floating down the Humber River, a waterway that feeds directly into Lake Ontario.
Fieldwork will begin in August 2014 to identify other hotspots and to take core sediment samples from the bottoms of Lake Ontario and Lake Erie. Corcoran and her team will use these samples to identify how much plastic has already accumulated, the date it started and the rate at which it continues to accumulate. Corcoran's team is collaborating with the Ontario Ministry of the Environment and Environment Canada on this pioneering research.
Core samples from the lake and the pathways feeding into it have the potential to launch future research into the effects of plastic on our own lives. Current research already shows that seabirds are attracted to plastic pellets and will keep eating until their digestive tract is full, eventually starving from nutrient deprivation. Littered shorelines, both with plastics and seabird guano, are not only unattractive to tourists but are potentially detrimental to the health of children who play in the sand.
Plastic debris provides transportation for pollutants and non-native organisms to hitchhike into our freshwater ecosystem. And yet another recent study discovered plastic fibres in the stomachs of fish from Lake Erie. This is particularly significant given that approximately 65 million pounds of fish are harvested from the Great Lakes every year.
Collectively, these outcomes are posing some very serious questions for Canadians: How much plastic can these animals eat? Can the toxicity from plastic pellets be transferred to the people who eat the fish? What is the long-term impact on animal populations, tourism, natural habitats and ecosystems?
Corcoran's pioneering research into pathways and hotspots for plastics, the rates at which they are accumulating, and the quantities that are already here, are setting the stage to answer these questions.
"Only then," says Corcoran, "will we be able to identify what the effects truly are and understand the real impacts."


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Severe drought conditions persist in Nebraska and Iowa
By Katie Knapp Schubert • Aug 2, 2012
All of Nebraska and Iowa are experiencing drought conditions, according to a new report.
The latest U.S. Drought Monitor was released Thursday morning. 83 percent of Nebraska is in an extreme to exceptional drought, up from 64 percent last week. 30 percent of Iowa is in an extreme to exceptional drought.
National Drought Mitigation Center officials say this year's drought is unusual because it developed and intensified quickly. Only 0.01 inch of rain fell in Omaha in July, according to the National Weather Service.
47 Nebraska counties have been declared primary natural disaster areas due to drought conditions.


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since 6% of the alarms are defective, probability of failure =q=0.06
p = 0.94
k =number of successes in n trials= 24-2=22
Use the pmf of the binomial distribution to find P(K=22)
A manufacturer produces 24 yard alarms per week. Six percent of all the alarms produced are defective. What is the probability of getting two defective alarms in one week?
I've identified the parameters
n = number of trials = 24
p = the probability of success p = 0.06
q=1-p = probability of failure = 0.94
x = the number of sccesses in n trials and 0<=x <= n x=2
P(x) probability of getting exatly x successes in n trials(I have to find out)
I can calculate P(x) using IT(Winstats) but I don't have it, any other ways to calculate it?


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Oh my, where has the week gone?! I have been totally overbooked this week. And last night, a glass of red wine, comfy pants, and dirty [gossip] magazines took over my productivity to take part in WIAW (What I Ate Wednesday). So, instead I am going to share with you What I Ate [and Did] on Tuesday, because that has been the most interesting day of my week thus far.
I rolled out of bed to hit the pavement and get some HIIT (High Intensity Interval Training) with the sunrise. I am trying to improve my running pace, and intervals seems to be the way to do it. After a 10 minute warm up, I did 6 x 30 seconds fast followed by 60 seconds of recovery, then a 10 minute cool down. Quick and Dirty. Normally, I eat before I exercise in the morning, but I didn't this morning, because I just rolled out of bed and sometimes eating just before running does not sit well with my stomach, plus I was only planning on running for about 30 minutes. Afterwards I came home, did some stretching and whipped up an egg scramble.
In the mix: carrot, onion, green pepper sauteed in 1 teaspoon coconut oil. 2 large pasture raised eggs, chopped spinach, cherry tomatoes, 1/4 avocado, and 1/2 cup re-fried pinto beans sprinkled with sesame seeds. I am seriously in love with the texture of re-fried pinto beans.
Mid-morning I snacked on some cucumbers and homemade hummus with the Food Of The Day–Orange (a-la-iTouch)! I am now getting in to foods that were on the "yellow" level of reactivity from my food sensitivity test, but so far I have not had any problems with any of the foods I have added. An update on how that is going will be coming soon!
Lunch was a re-formatted version of Sunday's pizza dinner.
I cooked up some Tinkyada brown rice fettuccine noodles, tossed them with about 1/4 cup of the tomato pesto from Sunday, and served them with some spinach, leftover chicken, kalamata olives, fresh basil, and a few dollops of cashew cheese. Delic-i-ous-o!
I worked my way through the afternoon seriously looking forward to my afternoon smoothie, and it sure lived up to its expectations.
In the Mix:
- 4 ounces homemade cashew milk + 4 ounces water
- 2/3 cup frozen blueberries
- 1 teaspoon vanilla
- 1 serving brown rice protein powder
- 1 tablespoon unsweetened dried coconut flakes (added an awesome texture)
- 2 teaspoons of chia seeds, stirred in after blending to maintain their "wholeness"
On the way home from work I swung by the gym to do a little quickie leg workout that has been in the queue since She Rocks Fitness sent it to me! I warmed up for 5 minutes on the elliptical and then did 3 sets of 15 repetitions (on each leg) with 1 minute rest between each of the following super sets.
- Lunge using the Smith Machine
- Single leg kettle bell dead lift
- Leg press
- Curtsey squat with dumbbells
- Walking lunges with dumbbells
- Step ups with dumbbells
In total, it took me 40 minutes and my legs were shaking walking back to the car! And I am still feeling it today! Almost worse than the day afterwards–that is some serious DOMS (delayed onset muscle soreness). Good thing I had a protein packed dinner waiting for me at home.
1/2# ground lean turkey, 1/2# ground Colorado lamb burgers with 1/2 diced green pepper, 2 tablespoons diced red onion, 2 tablespoons chopped fresh parsley, 1 large clove of garlic, sea salt and pepper. Cooked at 400 degrees for 15 minutes. Served with a lettuce bun, tomato, dijon mustard (Monday's Food Of The Day), and no-mayo coleslaw (without the hot pepper and green onions). Adding the dijon mustard to my diet was a bit of a stretch, because the brand I used contains a mystery ingredient of "spices". There very well could be a spice in there that I haven't tested or was high on my reactivity list, but I combed the shelves at Whole Foods and Natural Grocers looking for a mustard without unknown ingredients and this was the best I could come up with. I felt okay afterwards, so I am not too worried about it. I really should learn how to make my own mustard–that would be fun!
Today is turning out to be an accidental rest day, and it was well deserved.
Something to think about…Do you have things, activities, or people in your life that you identify as "energy robbers" where they just suck all the living energy out of you? How do you deal with them?


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About heyyitsemilia : I'm actually attractive if you don't compare me to anyone else. lol jk.
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Today, I have to get an ultrasound at the hospital. In order to get a clear picture, I need to have a full bladder. I've been waiting my turn for 2 hours now, desperately needing to pee. There are still multiple patients ahead of me. FML
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Today, I was in the shower with my boyfriend, and things started to get heated. That's where it all went to hell; I slipped and fell, bringing down with me the curtain and grooming products, and putting my back out. There goes my sex life. FML
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It s a perilous week for NFL prognosticators as teams with nothing more to prove or accomplish some of them matched against teams that still do give some R&R to injured stars and other key players. Blade pro football writer Dave Hackenberg is especially wary coming off of a rare losing week. All picks are against point spreads:
Last week: 6-7.
Season: 129-107.


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The impact of demographics on financial markets was the focus of the 2011 Robeco Summer University.
There, Klaas Smits, Robeco's Head of Food & Agri Strategies, met up with Charles Riemenschneider, Director of the Investment Centre of the United Nations' Food and Agriculture Organization (FAO), to discuss the roles that private capital and foreign investment will play in boosting global food production. For the full interview, please see: http://landing.quadia.nl/video/robeco/?m=99527.
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The Ottawa 67's make their way to the General Motors Centre on Sunday where they will take on your Oshawa Generals. This will be the third meeting between the two clubs this season, with the Generals winning both decisions so far. Puck drop is at 6:05pm.
The 67's and Generals last met on November 23rd, with Oshawa defeating Ottawa 4-2 with Boone Jenner, Scott Laughton and Tyler Biggs all picking up 2 points each in the win. Ottawa continued their dominance on the powerplay, scoring both their goals on powerplay chances. Coming into the game tonight the Generals sit second in the East Division with a record of 19-12-1-2, while the 67's sit near the bottom of the division with a record of 9-23-0-3. The 67's won four of the six games to give themselves the edge in the season series last year.
The Oshawa Generals were last in action on Friday night when they hosted the Belleville Bulls for the 15th annual Teddy Bear Toss night. The Generals opened the scoring when Chris Carlisle nabbed the Teddy Bear Toss goal late in the first. The Generals organization collected 5470 stuffed animals for the Children's Aid Foundation. Oshawa never gave up the lead, even when Belleville found new momentum late in the third, holding on to win 3-2. Daniel Altshuller picked up the win in net.
Ottawa was also playing Friday night, taking on the Peterborough Petes. Peterborough scored first but Ottawa answered with 4 back to back goals. After taking a 5-2 win, the 67's swept the 3 star selection with Dante Salituro taking the first star. Clint Windsor picked up the win in net, stopping 32 of 34 shots.
The Generals player to watch is Scott Sabourin. Currently undrafted, Oshawa's overage winger has had a scoring touch all season. He is currently third on the team with 14 goals behind Tyler Biggs (15) and Boone Jenner (27). Sabourin has been fantastic without the puck as well, creating scoring chances for his teammates by screening the goalie, or setting up plays with his passing. His +10 rating has been on a constant rise the past few games and he'll be playing big minutes with several key players away for the World Junior Championships.
Fans should also keep an eye out for 67's forward Tyler Graovac. Recently returning from Team Canada's training camp, look for him to play with some fire. The leading scorer on the 67's lineup, Graovac and teammate Sean Monahan are reasons why Ottawa's powerplay has been so effective all season. A draft pick of the Minnesota Wild, Graovac will be pushing to bring his team back into a playoff position.
The General next game is on December 28th, when they travel to Mississauga to take on the Steelheads. The Gens will return home to the General Motors Centre on Dec. 30th, when they host the Owen Sound Attack, and later when they host the Guelph Storm on New Year's Day, January 1st, at 2:05 PM.