text:
Public employees in Ohio may review and copy their personnel file, as well as put rebuttals in the file to answer unfair information.
There is no law giving private sector workers the right to see their own personnel files.
If you have a union, you have many more rights. Your union contract may give you additional rights to review your file, have copies, or remove unfair information. Ask a shop steward or representative. Personnel files can almost always be reviewed during a grievance or discipline. Information in your file can be very important during discipline or promotion.
You do not have the right under state law to see your personnel file. First, investigate if your employer has a policy that employees can review their personnel files (check your employee manual and ask other employees). If there's no policy which says employees can review their file, it's still worth asking. It may be best to ask verbally (maybe you'll be allowed to review your file without the person you are asking checking for approval). Decide who is most likely to let you see the file, probably either HR/Personnel or your supervisor. You can also read "How to Review Your File and What to Expect."
The rules:
- All public workers (state, county, city, town, and school district) have rights under this law.
- You (or anyone your give written permission to) can review your personnel file.
- Your employer is allowed to make reasonable rules about reviewing personnel files, but they must give access and copies in a reasonable amount of time. Ask the Personnel or HR office what the procedure is for reviewing your file.
- If there is no procedure on how to review your file, ask in writing and keep a copy, so you have proof that you asked. You can use the request form on this page.
- You can ask for the copies to be mailed. You can be charged the costs of copies, materials, and postage. You can be asked to pay before copies are mailed.
- This law does not include a right to see medical records or records of confidential investigations by law enforcement.
- If there is something in your file that is incomplete, wrong, irrelevant, or out of date, you should first ask that the information be taken out of your file or corrected.
- The agency has to investigate and decide if there is a problem with the information.
- The agency has to tell you the result of the investigation and what they are going to do within 90 days.
- If the information is not removed or corrected, you can put a short rebuttal in the file (explaining why it is wrong). Your statement must be kept in your personnel file and attached to the document any time it is used. You can use the form on this page when you submit a rebuttal statement.
NOTE: The Ohio Public Records Act lets members of the public ask for public records. The law specifically prevents giving out home addresses and family information for peace officers, firefighters, paramedics and EMTs, parole officers, assistant and prosecuting attorney, correctional employees, and youth services employees.
The Law: Right to review and have copies of a personnel record: Ohio Public Records Act, Ohio Revised Code 149.43 Right to put a rebuttal into a personnel file: Ohio Revised Code 1347.09
How the law is enforced: You have to bring a "mandamus action" in County Common Pleas Court. If you win, the agency that refused to give you access to your file can be ordered to pay for your lawyer's fee.
If you have a union, you have many more rights if your rights are violated. Talk to a shop steward or union representative.


text:
Sayre Veterinary Acupuncture
Sayre Veterinary Acupuncture provides acupuncture sessions, nutritional counseling and Chinese Herbal Medicine (TCVM) for dogs, cats, and horses. Our office is located in Port Matilda, PA in Centre County.
Dr. Mary Ellen Sayre graduated from the University of Tennessee, College of Veterinary Medicine in 1997. She has worked in small animal private practice in Harrisburg and State College since graduating. In 2009 and 2010 she took and completed the International Veterinary Acupuncture Society certification course and is a Certified Veterinary Acupuncturist. She is currently studying Chinese Veterinary Herbal Medicine through the College of Integrative Veterinary Therapies.
In May 2011 Dr. Sayre started a holistic veterinary practice. Her mission is to improve the quality of life to animals through integrative methods that promote the philosophy that every animal is an individual and the body has innate means of healing itself.
Dr. Sayre lives with her family, dog, cat and chickens near State College, PA.
If questions or to schedule an appointment:
- Phone: (814) 404-2466
- Email: firstname.lastname@example.com

subset: commoncrawl


text:
You guys, I stopped at home before getting the kids from pre-school today and literally threw this crock-pot meal together in minutes. I didn't have a recipe but I used ingredients that you can most likely find in your home and it turned out great!
My family really enjoyed this comfort meal; definitely a keeper!
Creamy Crock-pot Chicken
4 boneless, skinless Chicken Breasts
1 FAMILY SIZE can Light Cream of Mushroom Soup
2 Tbsp. Butter
1/2 cup 2% Milk
1 Packet of Dry 'Good Seasoning' Italian Dressing Mix
Pepper (do not add additional salt)
1 small Package Sliced Mushrooms (I've used 2 packages of mushrooms too; yum!)
Egg Noodles or Mafalda Pasta (I used Mafalda Pasta Noodles)
Season each piece of chicken with a dash of pepper and place at the bottom of your crock-pot.
Sprinkle Good Seasoning Packet over chicken.
Place sliced mushrooms all around and on top of chicken.
In a separate bowl, Mix Mushroom Soup and milk together and then pour over chicken.
Drop little bits of butter over chicken.
Cover and Cook for 6 hours.
Serve over Egg Noodles or Mafalda Pasta
We enjoyed this dish with steamed green beans!
Using Light Campbell's Soup decreases calorie intake.
I know, I know. Where are the mushrooms in the photo? I forgot. But don't be like me; the mushrooms make the dish complete!


text:
Release Date: January 1st, 1999
R|1 hr. 29 min.
Plot Summary
When warrior Beowulf (Christopher Lambert) learns that the inhabitants of the Outpost are being killed by a monstrous creature named Grendel, he offers to help the king, Hrothgar (Oliver Cotton), fight off the beast. The beleaguered fighters are grateful for his help, but a warrior named Roland (Gotz Otto) grows jealous of Beowulf when he sees him with the king's daughter (Rhona Mitra). As Beowulf learns more about Grendel, he realizes how much danger they all are in.
Cast: Christopher Lambert, Rhona Mitra, Oliver Cotton, Gotz Otto, Layla Roberts, Brent J. Lowe, Patricia Velasquez, Charles Robinson
Director: Graham Baker


text:
Amon Amarth
Amon Amarth has a long history with Metal Blade that goes back to their debut album, 'Once Sent from the Golden Hall'! After almost 20 years later, it's now time for a vinyl re-issue of this album, as well as 99's 'The Avenger'.Read More
Armored Saint
For a preview of 'Carpe Noctum', a live video of 'Aftermath' from the Aschaffenburg show can be viewed at metalblade.com/armoredsaint - where the new Metal Blade Records pre-order for Carpe Noctum has also been launched.Read More
Irish pagan metallers Primordial have announced the release of the first live album in the band's history, 'Gods to the Godless'. To hear the live version of 'Wield Lightning to Split the Sun', head over to NoCleanSinging.com nowRead More
Metal Blade Records has announced the next batch of classic albums to be included in the label's 'Originals-Series': Immolation's 'Close to a World Below', 'Failures for Gods' and 'Here in After'!Read More
New Releases
New Releases
Latest News
Monte Pittman streams new track, "Be Very Afraid", online
- September 13th, 2016 – There are great guitarists, great vocalists...Read More
Good Tiger premieres new video for "Aspirations" via AltPress.com – alongside exclusive interview with Derya "Dez" Nagle
- September 13th, 2016 – Kicks off North American tour with Dance Gavin...Read More
Armored Saint launches PledgeMusic campaign for new live album
- September 9th, 2016 – Photo credit: Stephanie Cabral Having toured...Read More
Allegaeon launches mini studio documentary for new album, 'Proponent for Sentience', online
- September 9th, 2016 – On September 23rd, melodic death metal outfit...Read More
Poison Headache launches live video for "Rot With Me"
- September 9th, 2016 – Set to join Killswitch Engage, Noisem for west...Read More
Visigoth announces "Warstorms Over Western Shores" headlining west coast tour
- September 9th, 2016 – This October, Salt Lake City's Visigoth...Read More
Wovenwar reveals details for new album, 'Honor Is Dead'
- September 7th, 2016 – Launches concept video for new track,...Read More
Charred Walls Of The Damned's Richard Christy launches drum play-through for new track, "My Eyes"
- September 6th, 2016 – Charred Walls Of The Damned – the...Read More


text:
Project ID: 2002CA4B
Title: Voluntary Compliance Versus Mandatory Sanctions: A Natural Experiment in Water Quality Regulation
Project Type: Research
Focus Categories: Water Quality, Law, Institutions, and Policy, Agriculture
Keywords: water quality, voluntary compliance, command-and-control, livestock, dairy
Start Date: 03/01/2002
End Date: 02/28/2003
Federal Funds: $10,000
Non-Federal Matching Funds: $15,495
Congressional District: 43
Principal Investigator:
Paul Sabatier
University of California, Davis campus
Paul Sabatier PI
Dept of Environmental Science & Policy, Davis campus
email: firstname.lastname@example.com
phone: 530-752-8898
The PI will share with 4 other PIs from California in the award allocation.
The research will evaluate the voluntary compliance approach to water quality regulation being practiced in the dairy and livestock industries in counties north of San Francisco Bay. It will explore the relative effectiveness of voluntary compliance versus manditory sanctions and how compliance has improved water quality. It will explore which of the hypothesized mechanisms are important e.g. education and outreach, promoting an environmental ethic, trust-building. The research will include an original analysis of 9 years of water quality data and an original survey of all dairy and livestock producers in the region.


text:
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to maintaining your privacy and will not share your personal information without
your express consent. For more information, please refer to our Privacy Policy.
LICHENSTEIN, SARAH BS; MCDONOUGH, ANNETTE PhD; MATURA, LEA ANN PhD
The purpose of this study was to gain an understanding of how caregivers of people with pulmonary hypertension are using an online discussion board. The chronicity and complex medical needs of people with pulmonary hypertension warrant a holistic nursing approach combining the patient and caregiver concerns to adequately address their needs. A qualitative descriptive approach was utilized. A convenience sample over an 18-month period of those caregivers who posted Internet messages to the Pulmonary Hypertension Discussion Board was included. Sociodemographics collected were age and gender of the person with pulmonary hypertension and the relationship of the caregiver to the person with pulmonary hypertension. Clinical variables collected were medications and oxygen use and years since diagnosis. Thematic analysis was used to identify themes. A total of 98 caregivers posted to the discussion board during the 18-month period; 46% of those posting were mothers of children with pulmonary hypertension. Four themes emerged: fear and frustration, questions and concerns, someone to listen to, and moving on with life. These themes characterize how caregivers of people with pulmonary hypertension were using the discussion board. Caregivers of people with pulmonary hypertension may need more information and support from their healthcare providers to adequately care for those with pulmonary hypertension.
© 2013 Wolters Kluwer Health | Lippincott Williams & Wilkins.
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text:
Listen Radio MQFM 1027 Online
Listen Radio MQFM - 102.7 FM Bandung Online Radio FM:
Title: Radio MQFM 1027 Online Radio
Country: Indonesia: Bandung
Site: http://www.mqfm.co.cc/
Station Phone: Call (022) 200-5131
Station Address: MQFM 102.7 Bandung
Jl. GegerKalongGirangBaru no.11
Radio MQFM 1027 Listening Tips:
If you like to listen to Radio MQFM 1027 online radio, kindly share this radio station streaming with your friends through Facebook like, Google+, Tweets, or other sharings. Also, you can bookmark this online live radio by pressing CTRL+D so that you can have quick access and listen to Radio MQFM 1027 live radio anytime you want.
Listen Online 24 provides you with the options to choose different Radio MQFM 1027 radio streaming source. If the first source link is broken, you can try the second source link and so on. Also, you can listen Radio MQFM 1027 online using diffrent players. For each link source, you can choose different players to listen. Just test out different players to see which plugin is more suitable for you.
If you have trouble or problem listening to Radio MQFM 1027 radio station, you can visit the Radio MQFM 1027 official site by clicking the link given.


text:
Effective Date: August 22, 2001
Expiration Date: July 13, 2017
Chg #
Revalidated with administrative changes to include content and structure to comply with NPR 1400.1, NASA Directives Procedural Requirements, updated Section 3 Authority & Section 4.
a. It is NASA's policy to provide guidance on the appropriate use of civil service personnel and service contractors through the following methods:
(1) NASA will employ civil service personnel for those scientific, engineering, technical, policy, management, and administrative functions which are inherently governmental. The use of contracts for performance of inherently governmental functions is prohibited. Office of Federal Procurement Policy (OFPP) Circular A-76, articulates relevant considerations to apply in determining whether specific functions are, as a matter of policy, inherently governmental.
(2) In those situations where contractors closely support the performance of inherently governmental functions, special control measures are advised. Examples of control measures that may be employed are:(a) developing performance based statements of work and quality control plans that measure contractor performance; (b) establishing audit plans for periodic review of contracts; (c) and physically separating contractor personnel from Government personnel; (d) consideration should be given to clearly differentiating contractor personnel by use of different colored badges, special identifiers in telephone directories, identifying company affiliation when answering the phone, or company identifiers on e-mail addresses.
(3) NASA will ensure that improper employer/employee relationships between civil service personnel and service contractors (e.g., unauthorized personal services contracts) do not develop in the administration and implementation of non-personal service contracts. Proper contract administration is critical in situations in which an employer/employee relationship may develop because contractor employees are collocated with NASA employees and support the same organization. In addition, NASA will, to the maximum extent possible, obtain services by means of performance based service contracts which require minimal technical direction from NASA personnel.
(4) In situations where it is determined that contractor personnel are needed to assist in the evaluation of proposals, the procedures set out in the Federal Acquisition Regulations (FAR) Subpart 37.2 and NASA FAR Supplement 1815.207-71 will be followed.
(5) The NASA civil service workforce will maintain the expertise to independently evaluate contractor performance including approaches, methodologies, options, results, recommendations, or conclusions.
a. This NPD is applicable to NASA Headquarters and NASA Centers, including Component Facilities and Technical and Service Support Centers, with the exception of the Office of the Inspector General.b. In this directive, all mandatory actions (i.e., requirements) are denoted by statements containing the term "shall". The terms: "may" or "can" denote discretionary privilege or permission, "should" denotes a good practice and is recommended, but not required, "will" denotes expected outcome, and "are/is" denotes descriptive material. c. In this directive, all document citations are assumed to be the latest version unless otherwise noted.
National Aeronautics and Space Act, as amended, 51 U.S.C. § 20113 (a).
a. Definition of Employee, 5 U.S.C. 2105, Chapter 21.
b. 5 CFR Part 210, "Basic Concepts and Definitions."
c. Federal Acquisition Regulations (FAR) and NASA FAR Supplement (NFS) References: (1) Inherently Governmental Functions, FAR pt 7.5;(2) FAR: Purchase Descriptions for Service Contracts, 48 CFR, pt 11.106; (3) FAR: Service Contracting, 48 CFR pt 37; (4) Handling Proposals and Information, NFS pt 1815.207; (5) Release of Proposal Information, NFS pt 1815.207-70; (6) Appointing non-Government Evaluators as Special Government Employees, NFS Part 1815.207-71; (7) Service Contracts, NFS Part 1837,
d. Office of Federal Procurement Policy Circular A-76, Attachment A
e. NASA Procurement Information Circular (PIC) 07-02, Acquisition of Services.
f. Title 5, Code of Federal Regulations, Part 300, Subpart E.,Use of Private Sector Temporaries.
g. Equal Employment Opportunity Commission (EEOC) Enforcement Guidance Notice No. 915.002, Application of Equal Employment Opportunity Laws to Contingent Workers Placed by Temporary Employment Agencies and Other Staffing Firms. (Dec 3, 1997)
a. The Assistant Administrator for Human Resources and the Assistant Administrator for Procurement have the functional responsibility for issuing NASA policy regarding the use of civil service personnel or service contractors respectively.
b. Officials-in-Charge of Headquarters Offices and Center Directors will ensure that managers and supervisors under their authority are aware of this policy and the accompanying references.
c. Officials-in-Charge of Headquarters Offices and Center Directors shall ensure implementation of and compliance with this policy.
d. Any planned acquisition which would entail contractor performance of functions similar to those referenced in paragraph 1b. of this policy statement, shall be reviewed and approved by the responsible Center Director or, for Headquarters, by the Associate Administrator for Mission Support, prior to the issuance of any Request for Proposals for services.
Officials-in-Charge of Headquarters Offices and Center Directors will ensure reviews are being conducted to measure compliance with this NPD.
NPD 3310.1, Distinguishing Between Contractor And Civil Service Functions, dated December 10, 1997


text: Governor Appoints Recovery Chief By Bente Birkeland • Sep 20, 2013 TweetShareGoogle+Email Colorado has a new chief recovery officer to help oversee rebuilding in the wake of massive floods. Governor John Hickenlooper made the announcement on yesterday, saying the goal is to have state and U.S. highways reconnected by December 1st. Bente Birkeland has more from the state capitol. Listen Listening... / 1:18 Tags: FloodColoradorecoverynewsroomCapitol CoverageTweetShareGoogle+Email Related Content Udall, Bennet Seek Federal Aid 3 years ago FEMA Working For Quick Recovery For Colorado Flood 3 years ago


text:
You are Here:
/ Will Buffer Benefits Disappear?
Dave York is worried. He's afraid high land and corn prices and the expiration of Conservation Reserve Program (CRP) contracts will prompt farmers to take out many of the 1,300 miles of grass and tree buffers he's helped install along the streams and rivers in Carroll County. Those grass and riparian buffers not only look pretty, but they provide pheasant habitat, keep soil in place and filter out pollutants from rainwater runoff entering Carroll County waterways.
York is the district conservationist for Carroll County. As a USDA-Natural Resources Conservation Service (NRCS) employee he is part of a conservation partnership that includes elected district commissioners, federal, state and district employees and volunteers that are all involved with helping landowners improve their land and the environment. York's team works with local farmers and landowners on conservation strategies and practices that are tailored to meet resource concerns. In Carroll County, that can range from assisting producers with manure management storage and application issues to using terraces and buffers to slow and clean storm water runoff before it enters lakes and streams.
Carroll County has some of the most productive farmland in the nation. Half of the county is flat due because of glacial movement and the other half is rolling with windblown loess soils. Loess soils are highly productive for growing crops, but they easily erode, especially from hillsides. Loose soil becomes a pollutant when it enters lakes and streams. If chemicals, like phosphorus and nitrates are attached to it, the soil ladened runoff can cause major problems downstream. Those problems can include filling lakes with sediment and causing water treatment facilities the extra expense of removing nitrates and other chemicals.
Eleven years ago when he arrived in Carroll County, York recognized the problem and joined with others to attack erosion and improve water quality. The Carroll County Pheasants Forever (PF) chapter became a key player in the erosion fight. Grass and tree buffer strips along county waterways became an important tool in their battle.
"Early on," said York, "our team decided to make our buffers a minimum width of 66 feet. CRP rules said they needed to be 30 feet wide for water quality, but we wanted our buffers to count for habitat, too."
PF member and farmer Jim Riesberg says the Carroll County PF chapter has been very active in promoting buffers as a way to increase pheasant habitat. "Over the years," said Riesberg, "our chapter has provided native grass seed cost share to producers, we've hired a person to go door-to-door to promote buffers, our members have provided free labor and equipment to drill the native seeds, and we conducted a labor intensive letter campaign aimed at producers. In that letter, we gave each producer a map of their property showing where buffers should go and we outlined the financial benefit of installing buffers on their property. Years later, farmers are still bringing that letter into our NRCS office and asking about buffers."
Chip Wittrock, Carroll County PF president, says the numbers of pheasants have gone up with the number of buffer miles installed. Wittrock, who has 12-acres of buffers on his 40 acres of land, says it is not unusual to wake up now and see 60 to 70 pheasants on his property.
A key component of the buffers program has been CRP administered by USDA's Farm Services Agency (FSA). CRP is a voluntary program available to agricultural producers to help them safeguard environmentally sensitive land. Producers enrolled in CRP plant cover crops that are designed to improve water quality, control soil erosion, and enhance wildlife habitat. In return, FSA provides participants with rental payments and cost-share assistance. Contract duration is between 10 and 15 years.
In Carroll County, the current CRP base rental rate is $145 per enrolled acre. Incentives can push that incentive rate to $225.
"We have 100 CRP contracts representing 1,057 acres up for renewal in 2008," said York. "That represents about of 15 percent of the buffers we have in Carroll County. Over the next four years 60 percent of the land in CRP contracts will come up for renewal. We are hoping for a very high renewal rate."
Without a high CRP renewal rate York, Riesberg, Wittrock and Carroll County conservationists are concerned many of the buffer benefits will be lost. "We've seen water quality improve and pheasant numbers jump with buffers," said Riesberg. "We are hoping farmers renew their CRP contracts in spite of the high land and corn prices. In Carroll County we need the benefits of the buffers."
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Will Buffer Benefits Disappear? (PDF, 780 KB)
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text:
Luomo Size 8 Wedding Dress
Size: 8
Colour: White
Fabric: Silk
Beautiful Luomo designer wedding dress. Worn once, purchased for approx $3,000. The gown is very simple and not 'over the top'. It has 2 layers, one of satin and then layer of silk. Beading on the front, back and top of shoulders is crystals of silver and clear, very beautiful for photos. Small train. I am 5 ft 8, dress is approximately 1.5m in length. Professionally hand cleaned.
Informtion about the designer can be found at: http://www.luomo.com.au
Owner Name:
Sarah Boyes
Sandy Bay, Tasmania
21/08/2016 6:00 am
Ad has expired


text:
Fortnight For Freedom 2014
The American Catholic will again be participation in the Fortnight For Freedom-June 21-July 4 with special blog posts on the subject of freedom.
Here is the announcement of the Fortnight from the USCCB:
WASHINGTON—Catholic dioceses and parishes across the United States are once again encouraged to raise awareness for domestic and international religious freedom concerns during the third annual Fortnight for Freedom, June 21-July 4. The two-week celebration will focus on the theme, "Freedom to Serve," emphasizing the link between religious liberty and service to the poor and vulnerable.
"During the Fortnight, our liturgical calendar celebrates great martyrs who remained faithful in the face of persecution by political power—St. John Fisher and St. Thomas More, John the Baptist, Peter and Paul and the first martyrs of the Church of Rome," said Archbishop William E. Lori of Baltimore, chairman of the Ad Hoc Committee for Religious Liberty of the U.S. Conference of Catholic Bishops (USCCB). "This is a time when Catholics can unite themselves in prayer to the men and women throughout history who spread the Gospel and lived out Jesus' call to serve the 'least of these' in even the direst of circumstances."
Two nationally televised Masses will bookend the Fortnight. Archbishop Lori will celebrate Mass at the Baltimore Basilica on June 21, at 5:30 p.m. EDT. Cardinal Donald W. Wuerl of Washington will celebrate Mass at the Basilica of the National Shrine of the Immaculate Conception in Washington on July 4, at noon EDT. USCCB President Archbishop Joseph E. Kurtz of Louisville, Kentucky, will be the homilist at the July 4 Mass.
USCCB has prepared materials to help dioceses and parishes participate in the Fortnight, including templates and guides for special prayer services, a list of frequently asked questions about religious liberty, one-page fact sheets on current threats to religious freedom in the U.S. and around the world, and a study guide on Dignitatis Humanae, the Second Vatican Council's Declaration on Religious Freedom.
The heritage of all Americans is religious freedom. That heritage is under siege by the current administration that has trampled on American religious liberty in pursuit of transforming the country into something that the Founding Fathers would have rebelled against. A rededication to the principles of liberty so resoundingly stated in the Declaration of Independence 238 years ago is badly needed and that is why we are participating again this year in this Fortnight.
2 Responses to Fortnight For Freedom 2014
Excerpt from the letter to the Danbury Baptist Church
"Believing with you that religion is a matter which lies solely between Man & his God, that he owes account to none other for his faith or his worship, that the legitimate powers of government reach actions only, & not opinions, I contemplate with sovereign reverence that act of the whole American people which declared that their legislature should "make no law respecting an establishment of religion, or prohibiting the free exercise thereof," thus building a wall of separation between Church & State. Adhering to this expression of the supreme will of the nation in behalf of the rights of conscience, I shall see with sincere satisfaction the progress of those sentiments which tend to restore to man all his natural rights, convinced he has no natural right in opposition to his social duties.
I reciprocate your kind prayers for the protection & blessing of the common father and creator of man, and tender you for yourselves & your religious association, assurances of my high respect & esteem."
Th Jefferson
Jan. 1. 1802.
The HHS Mandate never passed by Congress or voted by the people. The HHS Mandate was added after Obamacare was passed. Obamacare itself is an opinion, a personal opinion, which was made public through the abuse of the office of president. This is why Chief Justice John Roberts laughed at us, called Obamacare a tax, while the same day in response the White House called it a penalty. Obamacare criminalized the observance of conscience and imposed a penalty for the acknowledgement of "our Creator".


text:
|Date added:
|June 18, 2012
|Downloads last week:
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text:
A.G Hospital & Lifestyle Center, Nagercoil
#16, Sannathi Street, Krishnancoil, Nagercoil, Tamil Nadu - 629001
- 3 Specialities
A G Hospital & Lifestyle center is headed by two young Physicians. Along with Dr.Enoch S.Suundaram and Dr.Gnana Mallika Enoch there are many other young people who have dedicated their lives to join hands in establishing and running this lifestyle center.They are more like a family than organization. They are a committed team with one mind and one purpose to fulfill the will of God and serve humanity.
In todays world, it is sad to know that most of the money, time and attention is given to hospital and health care related system than on promoting health and preventing diseases.
- Website : http://www.aghospital.net
- Cardiology
- Obesity
- Oncology
- Nutritional Therapy
- Hydrotherapy
- Massage
- Herbs


text:
By Thomas Garcia: Quay County Sun New Mexico Secretary of Taxation and Revenue Rick Homans spoke to about 50 Quay County residents on Wednesday, providing an overview of the American Recovery and Reinvestment Act in New Mexico. He also introduced several members of the New Mexico Recovery and Reinvestment Competitive Grant Advisory Team. "We are […]
Officials brief Quay County on grants
Community Notes: Ctiy's emergency sirens to sound off, Saturation patrols in effect
City's emergency sirens to sound offThe Tucumcari Fire Department and Tucumcari/ Quay County Emergency Management will begin testing the city's storm sirens at 10 a.m., Wednesday mornings. The first test will be
2/7 Police Blotter
The following is a sample of calls received during the last few days by the central dispatch office for Quay County, based at the Tucumcari Police Department. Wednesday • At 7:06 a.m., a male caller reported vandalism at a residence on south Sixth Street. An officer advised that the house had been egged. • At […]
Quinonez pleads not guilty to child molestation charges
By QCS Staff Gerado Alcala Quinonez, 25, plead not guilty to felony child molestation charges when he was arraigned Wednesday in
10-15-2008: Calendar
Calendar for Wednesday 10-15-08 October Today: 10 a.m. – 10:30 a.m. and 2 p.m. – 2:30 p.m., Story time for all children ages 2
United Way auction set for Wednesday
The annual United Way of Quay County Auction at Wells Fargo Bank kicks
Governor to support local projects
Chelle Delaney Gov. Bill Richardson met with local officials on Wednesday and
8-23 Obituaries
Lee Roy Rumbaugh, 79, of Minneapolis died Wednesday, Aug. 20, 2008 in Minneapolis. He was born Jan. 15, 1929, in Rexford, Kan. He was the hospital administrator at Dan C. Trigg Memorial Hospital. He served in the U.S. Air Force. Survivors include his wife, June; a son, Richard Leslie; and a daughter, Janet Lee Services: […]
Commission set to review racetrack applications Wednesday
Chelle Delaney The New Mexico Racing Commission will announce Wednesday the date it plans to declare its selection for the last remaining racetrack license in the state, according to the agenda for the commission's next regular meeting on Wednesday. The commissioners will also meet in a closed session to discuss three separate license applications, including […]
Tucumcari schools to hold late registration Wednesday
Parents and families who missed registering their children for the 2008-2009 school year are invited to attend "late registration" at each school building between 1 p.m. and 4 p.m. on Wednesday, according to a press release. "We had a great turnout at registration but some families were unable to make it. We still want them […]


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There's no doubting the fact that head coach Jim Mora has the UCLA Bruins football program trending in a positive direction.
The best part about that statement for UCLA fans is that it's true on two levels—the football field and the recruiting trail.
UCLA football is on the rise, and much of that has to do with Mora's ability as a recruiter. He's competed for and landed one of the best recruits in the nation, and this 2013 class will be looked back on as a very solid group of football players.
Let's get to know UCLA's 2013 recruiting class:
Note: Information via 247Sports, ESPN or Scout.com unless otherwise noted. Star ranking according to the 247Sports Composite Rankings.


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Posted 22 August 2013 - 11:18 PM
Posted 22 August 2013 - 11:41 PM
Im at work now dealing with the great unwashed with a big smile...
Posted 22 August 2013 - 11:54 PM
I am guessing mick burkes boots is Jordan burkes dad whom I had the pleasure to speak to at the Salford friendly and he is a knowledgeable and enthusiastic rugby league fan despite following Widnes. ...
Our season has been transformed in recent weeks with some awesome defence and commitment
We score some nice tries too with some flair which has been long lacking.
Tonight we were tough and hard. We are no push overs
Rhys Evans chase and tackle on Nicholson typified that
Why did Barrow pass forward when they should have walked in is beyond me
It was a turning point for me
Penny yet again was class as was his try however dodgy it was how it ended up in his hands
Harvey especially deserves a mention ...playing injured and proving his doubters wrong week after week
A good night. Well done to all.
Way back when Gary Chambers was first appointed he attended question and answer session at the Borough Social, one of Watto's testimonial events. He came across as a real genuine guy but one of the comments he made was that he wanted the Lions playing attacking expansive attacking Rugby and in recent weeks he has achieved this aim.
The guy has had a rough deal from a view on this forum and in the crowd ( understandably since some of the results and performances were poor) but credit is now due to him and all concerned. We now have a very strong team.
Posted 23 August 2013 - 12:04 AM
Well done to Swinton tonight... best team won but to be honest guys I think we deserved a BP !
Totally agree, only our dogged defence prevented this.
Posted 23 August 2013 - 12:10 AM
Let's go to 'Haven, and stay up in style with a win!
Haven yes! Let's charter a train to Whitehaven from Swinton station like we did to Workington (two trains) in the Cup back in 1964.
Posted 23 August 2013 - 07:04 AM
Especially well done GC who, according to our own 'Mystic Meg' was gonna throw the towel in a few weeks ago. It also seems congratulations may have to go to our Chair for his appointment in the first place.
Stay up or go down id all up to us. We want it, the lads want it and were gonna ave it!
"no-one knows what it's like to be the bad man.........behind blue eyes"
Posted 23 August 2013 - 08:58 AM
Couldn't believe it when York were in the lead and Hunslet were level with Sheffield...nearly choked on my chorizo! Though it shows anyone can turn in a performance at some time, so we need to go to Haven and get the 3.
Well done to all the lads and it's great to have the feedback from Mr Burke regarding how the lads feel.
Mustn't it be rubbish if you don't have promotion and relegation between leagues. You can be a ###### team in Superleague, languish at the bottom and "plan for next season", but where's the sporting fun in all that. It's been more exciting these last few weeks than when we won Champ 1.
...anyway that beer at the side of the pool will be getting warm....adios amigos and see you at Haven!
Posted 23 August 2013 - 12:45 PM
Well done lads, I managed to get the commentary on my ipad and the whole of Ireland was behind you.......well the Wiganers around the table. I ate my dinner and all my fingers!
Especially well done GC who, according to our own 'Mystic Meg' was gonna throw the towel in a few weeks ago. It also seems congratulations may have to go to our Chair for his appointment in the first place.
Stay up or go down id all up to us. We want it, the lads want it and were gonna ave it!
"Gary Chambers' post match quotes make me suspect he is seriously considering resignation."
I wonder who said that?
Its amazing looking back at the forum how things change so quickly in sport. How fickle we are as fans and how favour is so easily lost or won.
Some valuable lessons can be learnt by those who choose to from the last few weeks. Myself included.
Posted 23 August 2013 - 07:34 PM


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Marco Eneidi
Born on All Saints Day, 1956 in Portland, Oregon, Marco Eneidi's life in music began at the age of nine playing the clarinet while growing up in the San Francisco East Bay area of California. During high school he started playing the guitar in the finger picking style of the southern blues legends, played gut bucket bass in a jug band, and played clarinet in a Dixieland band which performed at nursing homes and the local pizzeria.
At the age of twenty, Marco decided to get serious about music and finally began to practice upwards of twelve hours a day. In 1978 he got his first real job in music. He was hired to be part of a C.E.T.A. sponsored band, playing swing and jazz standards twice a day at various nursing homes, schools and hospitals throughout Sonoma County in Northern California. It lasted one year, until he was accused of trying to sound like Ornette Coleman, then John Coltrane, and then fired for not wearing socks.Read more
CD/LP/Track Review
- Hell-Bent In The Pacific by John Sharpe
CD/LP/Track Review
- Cherry Box by AAJ Staff
- Cherry Box by Micah Holmquist


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BBC TV Agreement for Opera, Ballet, and Dance Relays 2013
3 April 2011
Equity & BBC agreemnent for opera/ballet/dance/theatre relays on public service sigital TV channels.
Mobisode Template for Day Players 2009
3 April 2011
Equity form of engagement to be used by producers making a mobisode production for non-principal cast members.
Mobisode Template for Principle Cast 2009
3 April 2011
Equity form of engagement to be used by producers making a mobisode production
PACT Agreement for Cinema Films 2010
3 April 2011
Equity & PACT Agreement for minimum terms and conditions for all Artists (excluding instrumental musicians and crowd artistes) when engaged for films produced primarily for theatrical (cinema) exhibition by Producers
PMA Guidelines for Internet-Only Productions 2009
3 April 2011
Equity & PMA guidelines for the engagment of artist for internet-only work.
ITC Agreement for Choreographers 2004-2007
2 April 2011
Equity & ITC agreement choreographers


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Thursday 8th December
Digital Sales Are Half Of Total UK Music Industry Income
Posted at 8:29AM Thursday 20 Feb 2014Digital revenues now account for 50% of the total UK record industry income, according to the British Phonographic Industry (BPI).
Digital album sales and a surge in streaming boosted total digital revenue in 2013 to £365m - up from £326m (a 45.5% share) in 2012.
Streaming revenue increased by 41%, bringing total UK revenue to £730.4m - the first growth since 2009.
The 1.9% increase comes despite a fall in physical album and single sales.
Income from subscription streaming music services such as Spotify and Deezer was the fastest growing sector, generating £54.7m.


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in the last few days was the acquisition of del.icio.us by Yahoo! that was announced on Friday.
Another big piece of news
I forgot to post about it the other day,
but Tom Coates continues to do some of the heavy thinking required to consider some of the recent innovations in new-ish webstuff. This time it's about tagging: Two cultures of fauxonomies collide. What's refreshing about Coates' writing is that while it's not academic in nature (much more accessible and not nearly as onanistic as much of the academic work in the domain), neither is it obsessed with the commercial side of things – his posts aren't about the next business model or monetizing X or Y.
Zeldman has posted
an interesing followup to his earlier article on folksonomies and tagging in general: Remove Forebrain and Serve: Tag Clouds II. "The intellectual problem is that tag clouds create a data world where subtopics are detached from their parents; where the very notion of parent/child relations no longer exists. The counter-argument is, who cares?"
Since it was published,
a few people have noted misgivings about the article by Janice Fraser that I linked to last week; notably Andre Torrez, maker of a great number of really cool things on the net. See also Kottke's A whole new internet?. I still like Fraser's piece, but it doesn't capture the whole story – the story you already know if you're a maker of things on the internet. But for a non-maker audience – reader, community participant, casual browser – I think the piece does have merit and is still worth a read.
Janice Fraser
of Adaptive Path: It's a whole new internet. As usual more technically-inclined people will scoff at this (and they have been dismissive since JJG's article on Ajax a few weeks ago), but they miss the point.
Tag clouds are the new mullets. "It is of course wrong to compare weighted tag clouds to mullets, mood rings, and similar instances of mindless pop-cultural detritus. Tag clouds are not dumb. Their smartness is why so many have rushed to use them. But ubiquity and repetition quickly turn sweets to ashes."
Joshua Schachter,
the guy behind del.icio.us, has taken some funding and is going to work on it full time.
I'm heading out now
to see Ed Bilodeau's talk on folksonomies at McGill's GSLIS. I'm super-curious to see how he presents it.
Wired News:
Folksonomies Tap People Power. A growing number of websites with user-created content are relying on user-generated tags, also known as folksonomies, to let people know what's available.
Louis Rosenfeld
weighed in on tagging and such in a good article on January 6: Folksonomies? How about Metadata Ecologies?. Read the excellent comments by Thomas Vander Wal as well.


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Kirishima Kaoru is the representative of the Fujido Groups while Daigo is a young executive of an American corporation. They are business colleagues by day and lovers by night. Although, Kaoru wishes that he could give up his job and indulge himself in sex with Daigo day and night! Unfortunately due to his deep-rooted insecurities, Kaoru continuously tests Daigo's affection through manipulations. And now, Kaoru's previous boss and lover, Ian, wants Kaoru back in his bed. Who will win in the struggle for power and love? The series goes like this: 1. Happy Yarou Wedding 2. Utsukushiki Kemonotachi 3. Virgin Love 4. Toriko ni Natta Kemono 5. Junai no Seinen 6. Kemono wa Ai de, Iyasareru 7. Playboy Amour 8. Oboreru Kemono no Koibito 9. Men's Love
Top Members
- No comments posted so far, be the first one!
- Volume 1
- 4 years ago...Junai no Seinen 4-5: Junai no Seinen
- 3 years ago...Junai no Seinen 4: Ch.4-5 [End]
- 4 years ago...Junai no Seinen 3: ...Virgin Love
- 4 years ago...Junai no Seinen 2: Utsukushiki Kemonotachi
- 4 years ago...Junai no Seinen 1: Happy Yarou Wedding
By editing this manga you will earn the editor title for this manga!


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Wild Sports Baltimore Ravens XL Tailgate Bean Bag Toss Shields
NOW: $199.99 (9% off!)
Was: $219.99*
Product Information:
Get ready for game time playing with the Wild Sports® Baltimore Ravens XL Tailgate Bean Bag Toss Shields. In the backyard or outside the stadium, these regulation-sized boards with Ravens graphics will show off your team pride in a big way. The boards are designed with collapsible legs and come with 16 oz. bean bags made with durable duck cloth for competitive play. Be sure to bring this fan favorite to your next outdoor event.
- Officially licensed bean bag toss
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Customer Reviews:
Rated 1.3 out of 5�by 3 reviewers.
Rated 1 out of 5�by mattinuniform Not worth it I had a complete set hand made (from wood) and delivered to my home for less then this...and it came with color coded bean bags....don't waste the money! If you want a great deal just ask me...or look up: Rich Forsythe on F a ce Bo Ok he is the first one that is on the list when you search, he makes these! October 1, 2014
Rated 2 out of 5�by SAS Nice with Flaws This was a XMAS gift for my husband. The wood is solid and I like how the legs fold under for storage. My concern was the NFL Shield sticker laid on top. The corners were peeling up and one of the wooden corners had some damage to it. There was also some bubbling in the sticker. For what they charge for this product it should be impeccable, and you are basically paying for the NFL logo so it needs to be perfect, which it was not. Luckily I bought it on sale with a big discount! January 1, 2014
Rated 1 out of 5�by Bugguy77 Save your money I bought these boards to use for game time fun at my house. They didn't even last for halftime. The graffic is a sticker applied to a wood board. The sticker had bubbles in it from being applied too fast or by someone who didn't really care. Also, the stickers on the original board were not removed so you could still see the outline of those stickers as well. The boards are held together with finishing nails and pulled loose after my first game. Don't even bother with these boards. You can build better ones yourself. September 22, 2013
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The Style Gallery is a great new way for you to view, love, and share outfit photos. It's meant to showcase
all the expressive, creative, and inspirational personalities of our community!
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Make a space in your closet for the most dazzling denim in the universe! Covered in a galaxy of splatter-paint stars amidst a purple-pink Milky Way that varies from pair to pair, these Cheap Monday jeans are so out of this world, they've even been featured in Elle Magazine! The skinny cut looks modern and marvelous, no matter the atmosphere, while the slightly higher rise and comfy fabric flatters a variety of celestial bodies. Worn with a white blouse, a tailored tuxedo jacket, and sky-high wedge booties, these skinnies will put you light years ahead of the style curve!
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Enter your Email address:
Wolters Kluwer Health may email you for journal alerts and information, but is committed
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your express consent. For more information, please refer to our Privacy Policy.
Glaser, Rebecca L. MD1,2; Dimitrakakis, Constantine MD, PhD3,4
From the 1Millennium Wellness Center, Dayton, OH; 2Department of Surgery, Wright State University Boonshoft School of Medicine, Dayton, OH; 3First Department of Ob/Gyn, Athens University Medical School, Athens, Greece; and 4Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD.
Received June 24, 2013; revised and accepted August 8, 2013.
Funding/support: None.
Financial disclosure/conflicts of interest: None reported.
Address correspondence to: Rebecca L. Glaser, MD, 228 East Spring Valley Road, Dayton, OH 45458. E-mail: firstname.lastname@example.com, firstname.lastname@example.com
This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivitives 3.0 License, where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially. http://creativecommons.org/licenses/by-nc-nd/3.0.
Objective: Experimental and clinical data support the inhibitory effect of testosterone on breast tissue and breast cancer. However, testosterone is aromatized to estradiol, which exerts the opposite effect. The aim of this study was to determine the effect of testosterone, combined with the aromatase inhibitor anastrozole, on a hormone receptor positive, infiltrating ductal carcinoma in the neoadjuvant setting.
Methods: To determine clinical response, we obtained serial ultrasonic measurements and mammograms before and after therapy. Three combination implants—each containing 60 mg of testosterone and 4 mg of anastrozole—were placed anterior, superior, and inferior to a 2.4-cm tumor in the left breast. Three additional testosterone-anastrozole implants were again placed peritumorally 48 days later.
Results: By day 46, there was a sevenfold reduction in tumor volume, as measured on ultrasound. By week 13, we documented a 12-fold reduction in tumor volume, demonstrating a rapid logarithmic response to intramammary testosterone-anastrozole implant therapy, equating to a daily response rate of 2.78% and a tumor half-life of 23 days. Therapeutic systemic levels of testosterone were achieved without elevation of estradiol, further demonstrating the efficacy of anastrozole combined with testosterone.
Conclusions: This novel therapy, delivered in the neoadjuvant setting, has the potential to identify early responders and to evaluate the effectiveness of therapy in vivo. This may prove to be a new approach to both local and systemic therapies for breast cancer in subgroups of patients. In addition, it can be used to reduce tumor volume, allowing for less surgical intervention and better cosmetic oncoplastic results.
The biological effect of testosterone on the androgen receptor (AR) prevents the proliferation of breast tissue and inhibits the growth of breast cancer cells.1-4 Since the 1940s, testosterone and testosterone pellet implants have been used to treat advanced breast cancer as well as menopausal symptoms in breast cancer survivors.5,6 However, in breast cancer tumors, both malignant epithelial cells and surrounding fibroblasts overexpress aromatase, increasing local estrogen production, which subsequently stimulates cancer cell growth.7,8
We have previously demonstrated that two 6.4 × 3.1–mm subcutaneous implants—each containing 4 mg of anastrozole combined with 60 mg of testosterone—were able to provide therapeutic levels of testosterone without elevation of estradiol (E2) levels in breast cancer survivors.9 We have also documented both the safety and the efficacy of this combination therapy in breast cancer survivors and in women without breast cancer, including a reduction in the incidence of breast cancer.9-11
This combination testosterone-anastrozole (T + A) implant therapy, delivered locally (intramammary/peritumorally) in the neoadjuvant setting, has several theoretical advantages, including higher doses of both testosterone and the aromatase inhibitor anastrozole being delivered directly to the tumor. With increasing monetary constrictions on funding of large trials, the neoadjuvant/presurgical setting will probably become increasingly useful in evaluating clinical response to novel therapies.12
The patient is a 90-year-old G2P2 woman with a history of menarche at age 14, natural menopause at age 43, and a family history of breast cancer (grandmother). She was found to have a suspicious left breast lesion on CT scan of the chest, which was ordered after a fall.
Subsequent mammogram on December 7, 2012 revealed a 2.4-cm-deep obscured mass in the posterior central left breast, consistent with CT findings. Ultrasound (US) of the left breast revealed a 2.4 × 2.3 × 1.7–cm (ie, tumor volumea of 5.12 cm3) suspicious mass in the subareolar 3-o'clock position. US-guided core biopsy was performed, revealing grade 2 infiltrating ductal carcinoma (estrogen receptor [ER]–positive, progesterone receptor [PR]–positive, AR-positive, and HER2-negative).
An oncology consultation recommended 20 mg of tamoxifen daily. The patient refused surgical intervention but complied with tamoxifen therapy from December 2012 through March 2013.
She was seen and evaluated at the Millennium Clinic on March 1, 2013. The patient was alert and oriented and in good health, with no history of diabetes or cardiovascular disease. Medical history was significant for depression, mildly elevated blood pressure, postherpetic pain syndrome, and elevated lipid levels. There was a slight thickening in the left breast at the 3-o'clock position at the areolar border, extending under the nipple-areola complex. There was no palpable axillary adenopathy and no skin or nipple changes. Initial medication list was extensive and included duloxetine HCl, lisinopril, atorvastatin, omeprazole, temazapam, aspirin, pregabalin, tamoxifen, and supplements.
US performed in the office reconfirmed the presence of a 2.3-cm-deep left subareolar mass, unchanged from her previous US on December 7, 2012.
A written informed consent form was obtained, and the patient agreed to intramammary placement of T + A implants. In addition, the patient was informed that the combination T + A implant was prescribed by a physician for a purpose for which it has not been specifically approved (ie, "off-label" use).
Through a 5-mm lateral incision, three compounded 60 mg T + 4 mg A pellets were implanted into the breast tissue surrounding the tumor approximately 1 cm superior to, 1 cm inferior to, and anterior to the subareolar tumor through a disposable trocar (Fig. 1). Tamoxifen was discontinued.
Follow-up examination of the left breast 2 weeks after intramammary T + A pellet implantation revealed a marked decrease in tumor size on physical examination and office US. The periareolar "thickening" was no longer palpable. By week 4, the patient's (previously unreported) left breast pain had subsided.
On April 16, 2013, 46 days after intramammary T + A therapy, follow-up left breast mammogram and US, performed at the original imaging center by the same radiologist, revealed a significant decrease in tumor mass size. On US, the tumor measured 1.6 × 1.1 × 0.8 cm, with a tumor volume of 0.74 cm3, indicating a sevenfold reduction in tumor volume compared with 5.12 mL on December 7, 2012.
Three additional implants (ie, total dose of 180 mg T + 12 mg A) were again placed peritumorally in the left breast on April 18, 2013.
Follow-up mammogram (Fig. 2) and US (Fig. 3) on week 13, again performed at the same radiology facility, revealed that the size of the carcinoma had continued to decrease, measuring 1.5 × 0.8 × 0.6 cm on US, with a tumor volume of 0.42 cm3. This 12-fold reduction in tumor volume from the original measurement equates to a 2.78% decrease per day (after therapy) and a half-lifeb of 23 days. The logarithmic response of the carcinoma to T + A therapy is evidenced by an R2 value greater than 0.99 (Fig. 4).
In addition, many of the patient's symptoms, including memory loss, physical fatigue, urinary incontinence, sleep disturbance, depression, and pain, improved with testosterone therapy. Adequate serum levels of testosterone, without elevation of E2, were confirmed on day 7 postinsertion (testosterone, 473 ng/dL; E2 <5 pg/mL), day 46 postinsertion (testosterone, 366 ng/dL; E2 <5 pg/mL), and again on day 7 after the second intramammary insertion procedure (testosterone, 345 ng/dL; E2 <5 pg/mL). Interestingly, the patient was able to discontinue several medications in addition to tamoxifen, including duloxetine HCl, lisinopril, and atorvastatin. There have been no adverse drug events with therapy. The patient "feels better than she has in years," is no longer using a walker, and is driving her car again. She continues to refuse any surgical intervention.
Follow-up US and mammogram are scheduled for September 2013, 6 months from the initial intramammary T + A pellet insertion. If a residual mass is present, an US-guided core biopsy will be performed to reevaluate tumor characteristics and hormone receptor status. The patient will be continued on intramammary therapy (180 mg T + 12 mg A) for a minimum of 1 year after complete clinical response. She will then continue to be treated with T + A implant therapy, possibly at alternate insertion sites.
Although there was virtually no response to oral tamoxifen therapy between December 2012 and March 2013 (as evidenced by tumor measurements on office US), our patient manifested a rapid clinical response to intramammary T + A therapy by 46 days, continuing through week 13. This was particularly evident when we compared three-dimensional tumor volumes over time, calculated using the ellipsoid formula,a which has been shown to be superior to using only the greatest (tumor) diameter.12
This innovative pharmacologic combination (T + A), unique delivery method (sustained-release implant), and unique delivery location (intramammary and peritumorally) in the neoadjuvant setting has many potential advantages both for research and for the local and systemic therapy of breast cancer.
The combination of testosterone delivered simultaneously with anastrozole allows the beneficial effects of testosterone on the AR and simultaneously prevents aromatization to E2. Testosterone is beneficial for immune function and treats many systemic symptoms, adverse effects of cancer therapies, and the breast cancer itself.1-4,9,13,14 The sustained-release combination implant ensures continuous, simultaneous delivery and absorption of both active ingredients locally at the tumor site while maintaining consistent therapeutic systemic levels of testosterone without elevating E2. We have previously published data on the safety and efficacy of these doses of testosterone and have shown that pharmacologic doses of testosterone—as evidenced by serum levels several fold higher than endogenous levels measured on week 4 (299.36 ± 107.34 ng/dL) and before reimplantation (171.43 ± 73.01 ng/dL)—produce a physiologic (therapeutic) effect and are not associated with adverse events.15 The only expected androgenic adverse effect in our patients has been a slight increase in facial hair. The safety of the 180-mg testosterone implant has also been confirmed in historic studies, where doses from 150 to 225 mg were routinely prescribed and doses up to 800 to 1,800 mg were safely used in the long term to treat metastatic breast cancer and female-to-male transgender patients.5,6,15,16 Contrarily, there is a lack of evidence to support that serum ranges from endogenous production should be extrapolated to exogenous therapy or used to determine implant dosing in lieu of "clinical efficacy" and "adverse effects." In addition to testosterone, the androgen precursors dehydroepiandrosterone sulfate (DHEAS) and androstenedione, found in much greater concentrations (up to 103-fold) than testosterone, also decline with age. We have found that higher serum levels of testosterone (supplied by the implant) are necessary to provide adequate amounts of testosterone to the AR, replacing not only testosterone but also the significant contributions of DHEAS and androstenedione to bioavailable testosterone.15
Unlike oral medication, patient compliance is not an issue with implanted pellets. Furthermore, the implant allows for lower, more efficient, and effective dosing of anastrozole. Subcutaneous delivery avoids the gastrointestinal tract and subsequent gastrointestinal adverse effects, including nausea, vomiting, and pain. There is no first-pass effect and no adverse effect on the liver or clotting factors.
The intramammary location is particularly unique in that it allows differential dosing. High doses of both testosterone and anastrozole are delivered locally, directly targeting the tumor, whereas lower therapeutic systemic levels are achieved. This is in direct contrast to neoadjuvant therapy by other delivery methods, including oral or intravenous, where higher systemic levels are necessary to deliver adequate dosing to the breast tissue/tumor site, resulting in greater systemic adverse effects and toxicities and less effective local therapy.
The neoadjuvant/presurgical setting also allows identification of responders (vs nonresponders) and early evaluation and documentation of the effectiveness of therapy.17,18 Moreover, in larger tumors, this therapy may allow for breast-conserving surgical operation, with improved oncoplastic cosmetic results.
This patient and several others who have responded to T + A therapy were AR-positive, consistent with testosterone effect on the AR.1-4 Interestingly, an 81-year-old patient with a clinical stage 2, ER-positive, PR-positive, AR-positive tumor, subsequently treated with T + A intramammary therapy, is also responding, although at a slower rate (1.87% per day, half-life of 37 d), with a logarithmic decline in tumor volume (R2 = 0.96). In addition, her palpable adenopathy is also responding to therapy.
In the future, it would be interesting to monitor response to T + A therapy among "triple-negative" (ER-negative, PR-negative, and HER2-negative) patients, who may be AR-positive. Contraindications to this therapy have not been recognized; however, caution should be exercised in ER-negative, HER2-positive patients; one study has shown that AR positivity was "associated" with poorer prognosis.19 Although an AR-negative tumor may not respond as well to this therapy, patients may still benefit from testosterone's anabolic effects on bone density, as well as testosterone's immunostimulatory, anti-inflammatory, and pain-relieving properties. Unlike higher-dose oral aromatase inhibitors, which can secondarily increase gonadotropin-releasing hormone and subsequently stimulate the ovary to reproduce estrogens, low-dose parenteral anastrozole, in combination with testosterone, may also prove to be appropriate in premenopausal hormone receptor–positive patients. However, until further studies are performed, older postmenopausal patients with hormone-positive tumors are considered to be the most appropriate candidates for this novel treatment.
The combination implant is also cost-effective, providing 2 to 3 months of therapy with a single, minimally invasive, 2-minute procedure at a cost of approximately US$2.00 to US$3.00 per day. In the future, this therapy may be used in conjunction with other endocrine therapies (such as tamoxifen) or sulfatase inhibitors, which prevent hydrolysis of estrone sulfate and DHEAS, both of which can be reduced to steroids with estrogenic properties in a low-estrogen environment.20
We have shown that this combination T + A therapy was well tolerated by this 90-year-old patient and effectively treated her AR-positive breast cancer. Neoadjuvant endocrine therapy for a grade 2, hormone receptor–positive breast cancer using intramammary T + A therapy resulted in a rapid clinical response (ie, 12-fold reduction in tumor volume within 3 mo).
A neoadjuvant study option allows the observation and documentation of clinical response and, if followed by surgical excision, the biology of tumor response. In addition, this therapy may allow for fewer surgical operations and improved oncoplastic results. Further research is needed to delineate the role of sustained-release T + A in both the prevention and the treatment of breast cancer. In the future, this combination may have the potential for both systemic and local therapies for breast cancer in subgroups of patients, possibly eliminating surgical operation, radiation therapy, and adverse effects of oral medication.
aEllipsoid formula: 4/3π (a/2 × b/2 × c/2). Cited Here...
bLogarithmic half-life equation: x = log(0.5) / log(1 − 0.0278). Cited Here...
Testosterone; Anastrozole; Breast cancer; Intramammary; Neoadjuvant
© 2014 by The North American Menopause Society.
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A slight positive theme has breezed through the markets today with most Asian equity markets holding on to gains. The Nikkei 225 retraced some heavy losses seen yesterday amid exporters benefiting by the JPY weakness. Sharp has been one of the top gainers, leading the local market on a Nikkei report, which said the Co. may sell its television factory in China to Lenovo Group. As a reminder, the Bank of Japan's policy meeting next week will be the next major crucial point for the JPY.
In terms of data, Australian employment change for December has been the primary focus, which came in surprisingly lower than consensus, printing at -5.5K vs. Exp. 4.0K. Consequently, AUD/USD fell 27 pips and continues to trend lower after this release. Interestingly, the disappointing job data has had little impact on the ASX 200, which has been the standout market so far, led higher by technology sectors echoing the US session. Participants are likely to pre-position ahead of the upcoming Chinese data, including Q4 GDP and December Retail Sales tomorrow with expectations that China's economy has expanded at a pace of 7.8% in Q4 Y/Y (Prev. 7.4%)
Looking forward, economic calendar remains on the light-side, but Japanese Nationwide Department Sales is scheduled to be released at 0530GMT/2330CST.
As of 0238 GMT:
ASX200 (+0.90%), Nikkei 225 (+0.18%), Shanghai Comp. (-0.79%), Hang Seng (+0.11%), KOSPI (-0.36 %)
17 Jan 2013 - 02:39 - Forex Data - Source: RANsquawk
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text: When you stay at Palace RRT Hotel Constanta in Constanta, you'll be near the beach and minutes from Great Mahmudiye Mosque and Constanta Casino. This hotel is within close proximity of Ovid Square and Archeaology Museum. Make yourself at home in one of the 99 air-conditioned guestrooms. Complimentary wireless Internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have showers and hair dryers. Enjoy recreation amenities such as a fitness center or take in the view from a terrace. This hotel also features complimentary wireless Internet access, wedding services, and tour/ticket assistance. Satisfy your appetite at the hotel's restaurant, which serves lunch, dinner, and brunch, or stay in and take advantage of room service (during limited hours). Quench your thirst with your favorite drink at a bar/lounge. Featured amenities include express check-in, express check-out, and dry cleaning/laundry services. This hotel has 8 meeting rooms available for events. Limited parking is available onsite. The recreational activities listed below are available either on site or nearby, fees may apply.


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Jim RossJames William Ross
- Birthdate: 01/03/1952 (age 64)
- Height: 5'10"
- Weight: 250 Ib
Jim Ross is an American professional wrestling ...
Jim Ross has posted his latest blog online. Check out the highlights:
On the WWE Network: "I'm still of the belief that, in time, the WWE Network will be a good investment for WWE but it likely will continue to evolve for the next 2-3 years as it relates to garnering a consistent number of subscribers and how the Network will be accepted and subsequently grow outside North America. By lowering the company's overhead, cutting the fat, so to speak, WWE will have more realistic numbers in place that will positively affect the Network's financial impact on the company."
On what fans want from the network: "My observations of the Network are that the younger fans want new programming to compliment what they are currently watching on WWE TV while many displaced fans, if they can be located in a reasonable, marketing manner, likely are going to like the content from the vault or programming that relates to the past the best. In other words, WWE has two, distinctly different audiences to market the network to and that cannot be done exclusively within WWE programming."
On how WWE can better promote the Network: "Plus, things like having their stars talk about what they watched this week on the WWE Network goes a long way in promoting the future of WWE which is the WWE Network. We rarely hear that. Same goes for the announcers. Organic promotion from all talents is easy to produced and to insert into any broadcast WWE produces. I'd suggest that WWE is under utilizing their powerful social media network to promote the WWE Network. For example, a tweet from John Cena, for example, on what he's watching goes a long way."
On what WWE should be producing for the Network: "When budgets allow for such, producing new programming for the network is imperative and one would think that there are endless ideas that could be utilized without incurring exorbitant costs. I'm not talking about major productions like Legends House but instead timely, one hour shows that create a platform for WWE talents to expand their skill set and to perform in a different arena. I'd love to see WWE produce more Legends Roundtables as they were fun and informative plus I think that the show, depending on the subject matter, could bridge the gap between today's fans and displaced fans of a generation ago. It's hard to navigate one's future if one doesn't understand the past."
On the staff cuts: "Cutting the fat, whether it be to our own bodies or to a company's overhead, is never a bad idea and it appears that through trial and error in a public forum of being a publicly traded company that WWE seemingly has a better handle on what they should and should not be doing from an infrastructure standpoint within the corporate world. Perhaps some executives might have to wear multiple hats in this all hands on deck state of their business. Hopefully, those that remain employed with WWE will do all they can to gain more product knowledge because it's impossible to adequately market to your consumer base if one doesn't know them, can't identify with them to some degree, etc. I used to say it all the time when I was in WWE, how does one have a successful career in WWE in any role if one is not a fan of the genre and is merely watching the product because they feel that they 'have to' or that Vince McMahon might ask them what they liked this week on RAW. I feel badly for those that have lost their jobs but hopefully they will land on their feet and positively move forward. That can be done as I can attest through personal experience. As far as the talent roster is concerned, if someone isn't evaluating the roster on virtually a daily basis as to who is on the bubble, who needs to improve in specific areas, etc then the job isn't being done as it should. It doesn't take long to determine what the likely ceiling is on any talent in the on going evaluation to find the next main event player at WrestleMania. Managing a talent roster means one is always in 'crisis mode' and WWE doesn't have a more valuable commodity or asset than their talent."


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Scott Stantis by Scott Stantis
- October 31, 2013
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It wasn't a glitch that messed this all up, that is only one tiny symptom in a system that is sick and rotten to the core.
I heard the same comments in 1944 when SS was just getting started.
Will Ted Cruz be reading this on the floor in another attempt to stop anything from getting done?
A follow-up to the popular series: The Insurance Industry that ran Health Care into the Ground.
Single payer. How many false starts do we need before we do what we all know needs to be done?
The SS got started in 1935 not 45… Oh! You meant Social Security…! My bad.
"I heard the same comments in 1944 when SS was just getting started."
Yeah, and look how well that turned out.
Bloated, bankrupt and sucked dry by corrupt politicians.
EXACTLY the same reasons reasonable people are opposing Obozocare.
History will keep returning you and your ilk to the ash heap. Unfortunately, each generation forgets the lessons of the past generation.
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Recording in my man-cave/studio: The process start to finish
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The Young And The Restless Spoilers For July 26 – 28.
We all know there's no love lost between Diane and Phyllis, who happen to be lusting for the same man. Nick is forced to step in between the rivals and orders the women to cool it. Phyllis isn't the only one gunning for Diane… Not only is Jack upset with her, and demands that she get Kyle on the phone pronto, Victor is furious when he finds out that Diane is suing Nikki.
Victoria is back in the saddle where work is concerned and is stunned to learn of Abby's new position. Don't expect another catfight to erupt though. The sisters decide it's time to celebrate and head out to do just that. However, when they run into Genevieve and ask if there's something they can help her with, Cane's mother replies, "I was hoping I could help you."
Adam can't keep his anger contained any longer. He lashes out at Sharon for betraying him and claims she deserves exactly what she gets. It's no secret Sam isn't a fan of Adam's, so look for the two men to get into it yet again. Adam isn't off the hook just yet… Victor warns that whatever Adam has up his sleeve, it'll backfire.
Wait, there's more… Chloe sees Billy and accuses him of following Delia and trying to lure their daughter away. And Jack and Lauren appear on "The Talk" to chat about their new Jabot venture.
More to come Friday…Until then, check out our "Y&R" spoilers over on Soaps.com, our sister site, or read Y&R weekly summaries, news, actor bios, appearances, video clips, polls and comings and goings, and please leave us a comment!
Join us on Twitter @soapoperafan, and Facebook. Come tweet and Facebook with us about "The Young And The Restless," all the other soap operas, "Glee," "Grey's Anatomy" and "Vampire Diaries!"
Photo Credit: Soap Opera Fan Blog
Fun fact! Amy Mistretta wrote this story just for you on July 26th, 2011 |


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Lavender Honey Winner
Well geeeez!
Remember that Mother's Day giveaway!? Yea? Just barely?
Big warm hugs and a giant thank you to all of you who shared stories about your amazing mothers. Your stories… phew! You got me cryin' a few times… I can't lie. Thanks for being so open and lovely about your moms. I loved reading all of your entries.
The winner of the dreamy Lavender Honey? Amy of Sing for Your Supper. Right on Amy! Way to go being comment 58! Way to go Random.org for being great at picking random numbers… like 58. Sweet!


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Managing the duplicate names while reading about the Wars of the Roses is quite the hassle. For instance, Richard Neville made an alliance with Richard. Richard Neville and Richard were killed at Wakefield in 1460. Hold on though, Richard Neville also died in 1471 at Barnet. How could that be possible? Because the doctor was a woman! Yes, like some lame riddle, the reusing of names that run through England's royal history is a baffling trial that will leave you behind if you're not closely paying attention. It's probably best then that Fatshark's War of the Roses focuses on a foot-soldier who is more concerned about avoiding arrows and sword swings than family lineage.
Catherine previewed the game back during this year's PAX East and she gives multiple reasons to get hyped about this sword and shield game. If you're already itching to don a rose and choose between Lancaster and York, Paradox has announced that they're accepting beta applications for the game's multiplayer. By going to this site here, players will both sign up for the beta and receive a referral link that- if five friends sign up through it- "secure[s] a spot in the beta," as the press release puts.
If you're interested in learning more about War of the Roses, you can read Catherine's preview here, watch a live stream of the game from Dreamhack on Paradox's Twitch TV archive, or watch this developer diary:
War of the Roses is scheduled for a third quarter release in 2012 for PC.


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What is in this article?:
- Herbicide resistant ryegrass troubling for wheat growers
- Other options
- Herbicide trials
- Glyphosate resistant pigweed currently may be attracting more attention, but to an increasing number of wheat growers, herbicide resistant ryegrass poses an equally disturbing dilemma.
Glyphosate resistant pigweed currently may be attracting more attention, but to an increasing number of Southwest wheat growers, herbicide resistant ryegrass poses an equally disturbing dilemma.
For several years, farmers, industry representatives and Texas AgriLife Extension specialists have noted that once-effective herbicides have failed to control some ryegrass in wheat stands.
A group of interested parties met at plots near Fairlie, Texas, to review control options for this increasingly worrisome problem.
Jim Swart, Texas AgriLife Extension integrated pest management specialist, has been looking at options for several years, especially after noticing that a control standard, Axial XL, was no longer effective in controlling some ryegrass. He said another once-effective herbicide, Hoelon, had been phased out of recommendations several years ago when ryegrass displayed resistance.
Last year Swart estimated about 10 percent of the wheat in northeast Texas showed resistant ryegrass infestations. "I think that's closer to 20 percent this year," he said.
Tony Driver, a tech representative for Syngenta, manufacturer of Axial XL, said the problem seems fairly localized "but must be taken seriously. This can be a serious problem if we don't address it."
The best solution so far is what Swart calls a "two-step program," a resistant ryegrass management system that keeps Axial XL in play. The program calls for application of Axiom, a Bayer CropScience herbicide, at 6 ounces per acre when you can "row your wheat. We don't want to apply until wheat is up to stand, as Axiom has some preemergence activity," Swart said. Following that, Axial XL is applied at 16.4 ounces per acre at the two-leaf stage of ryegrass, usually in early to mid January. "We add a half-ounce of Amber with Axial XL to control broadleaf weeds," he said.
That combination has taken out the resistant ryegrass. "And it keeps Axial XL available," Swart said. "Axial XL has been doing a good job and is still doing a good job in many places." He said using Axial XL in combination with Axiom allows farmers to keep a good herbicide available when ryegrass becomes resistant. "We really have nothing to replace Axial XL," Swart said.
He's looked at Axiom for about 12 years but until recently could find no real fit because "Axial XL was doing such a good job. Now, we can apply Axiom early and come back with Axial XL and take out resistant ryegrass."
Swart said a commercial field near the test plots failed last year and was overrun with resistant ryegrass. "They used the two-step program this year and will make a good wheat crop. This program is going to buy us a lot of time."
Gary Schwarzlose, Bayer CropScience tech service representative, said Axiom also has some broadleaf activity, mostly on mustards and henbit.
Swart and other industry representatives cautioned farmers to be alert to potential resistant ryegrass infestations and to watch for "slippage" of current herbicide programs.
"Pay attention when you combine wheat," Swart said. "If you see ryegrass at harvest following anAxial XL application, it may be resistant. And you can scatter seed all over the field with the combine."
Russell Sutton, Texas AgriLife research agronomist, said ryegrass seed spreads easily. "We can spread it with a combine, other farm equipment" or through natural means — wind, birds, etc.


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Living in a tropical paradise doesn't mean you get to sit on the beach all day, relax and surf. Just ask Asenati Petelo.
Even if she wanted to, Petelo is too busy to spend much time on the beaches of Hawaii, where she lives and works, because in addition to working a full time job she is in the U.S. Army Reserve, attends the University of Hawaii, and is a member of its ROTC program.
And as a Cadet, Petelo said she spent part of her summer at Cadet Command's Leader Development and Assessment Course, and the rest in Mongolia with ROTCs Cultural Understanding and Language Proficiency program.
The mission to Mongolia was a regularly scheduled multinational exercise which included 12 countries. It is sponsored by the U.S. Army Pacific and hosted annually by the Mongolia Armed Forces.
"The CULP mission helped me understand how peacekeeping missions operate and also, how cultures come into contact with the peacekeeping missions," she explained.
The actual exercise provided an environment that exposed participants to different ways of conducting peacekeeping operations. As the fictionalized scenario evolved it was designed to challenge participants to consider potential situations that may otherwise be overlooked.
For her part, Petelo was assigned the role of Public Affairs Officer during the battalion-level staff exercise.
"I was the brigade PAO during this assignment", she said. "I made sure media releases were sent out to all battalions and ensured that all the media products published by each battalion were aligned with the brigade's key messages and themes."
She said that this was the first time she had ever briefed at this level, and she had never briefed anyone higher than a captain before.
Lieutenants don't get to brief at the brigade level, and captains do it rarely, but she said she learned a great deal from the experience.
"I was nervous and scared at the thought of it but my all my shop officers encouraged me and told me that I could do it," Petelo explained. "I learned that as an officer, you need to do your best to be creative and to hold the audience's attention. And I should also maintain eye contact with each battalion commander and make sure that they taking necessary actions in order to get the job done the right way.
"I (really) think that this type of training is useful for Cadets' because it helps build the Cadets' morale and confidence in leading others. It will definitely help develop the Cadets into becoming greater leaders."
Petelo said that overall her experience at the Khaan Quest 2012 was something she enjoyed and from which she learned much.
"I was fortunate to work with foreign officers from other different countries. At an early stage in my officer life I was also blessed to be exposed to the different duties and responsibilities at each level within the Army organization," she said. "I worked directly with a Marine brigade, an Alaska brigade and a Mongolian brigade. And I experienced the importance task of a PAO on the brigade level as I was the role player for this position."
CULP is designed to immerse ROTC cadets in various languages, cultures and socio-economic situations so the Cadets can learn, through personal experience, that cultures are different and building relationships is important.
Petelo thinks she has accomplished what CULP was designed to teach, and now she will go home and pass on what she has learned, both as a Soldier and a civilian.
Petelo, who has been an Army Reservist for six years, will graduate in December from the university, and from ROTC, and plans on staying in Hawaii.
"I asked my recruiter if I can get a recruiting slot so I can recruit for the program and tell prospects about my route," she explained. "I want to tell them about the options because I didn't know (about them). I also plan on using my degree to work in (finance), maybe bank operations management."
Deciding to enter the Army Reserve was an easy decision, said Petelo, who is originally from the Samoan Islands. She said that culturally she is from a place where family is important and she wanted to stay close.
"I am the first in the family to go to college-- I received a Guaranteed Reserve Force Duty scholarship--and it is good to have family support," she explained. "With that in mind, my younger sister is also in the program---I recruited her last semester. I love the experience and can stay close to home---Hawaii is home and it still within the island mode."
Petelo added that her parents are supportive of her decisions and as soon as she is done with her degree they are pushing her to get her masters.
"Whatever I learn from the military I can apply to my job," she said. "At the same time I am giving back to my community. I am not only serving my country but, (I'm) serving on the civilian side which (means I am) offering what I have l learned from school.
"The education is what the Army gave me and I am giving back. I think it is important to give back to the community, whether it is serving in the military full time, or serving on the civilian side."


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The La Crosse City Council was split Thursday night on whether or not to extend the rental conversion moratorium.
In the end, 12 members voted to approve an additional 90 days to the ban on converting single family homes into rental properties.
It started back in July after it was made known that more than 700 single family homes were rentals. Since then, dozens of landlords have come forth looking for waivers to the moratorium, most because they were not properly registered.
Just like the council, residents are split on the end of the moratorium, but agree there's work to be done. "I think there's some issues, I don't think it's as bad as some people are suggesting. But I think there are some things that can be improved by better enforcement," said President-elect of the La Crosse Area Realtor's Association Kent Gabrielsen.
"We've gotten a lot of good feeling about people's commitment to this issue, but it takes time, and we understand that and that's why we wanted more time," said Jacob Sciammas of the Grandview- Emerson Neighborhood Association.
On Tuesday, a city committee presented the council with a series of ideas to address the increase in rental homes. Council members hope additional time will allow them to enact some of those ideas.