text:
Premique Low Dose 0.3mg/1.5mg Modified Release Tablets
Last Updated on eMC 06-May-2016 View changes | Pfizer Limited Contact details
- 1. Name of the medicinal product
- 2. Qualitative and quantitative composition
- 3. Pharmaceutical form
- 4. Clinical particulars
- 4.1 Therapeutic indications
- 4.2 Posology and method of administration
- 4.3 Contraindications
- 4.4 Special warnings and precautions for use
- 4.5 Interaction with other medicinal products and other forms of interaction
- 4.6 Fertility, pregnancy and lactation
- 4.7 Effects on ability to drive and use machines
- 4.8 Undesirable effects
- 4.9 Overdose
- 5. Pharmacological properties
- 5.1 Pharmacodynamic properties
- 5.2 Pharmacokinetic properties
- 5.3 Preclinical safety data
- 6. Pharmaceutical particulars
- 6.1 List of excipients
- 6.2 Incompatibilities
- 6.3 Shelf life
- 6.4 Special precautions for storage
- 6.5 Nature and contents of container
- 6.6 Special precautions for disposal and other handling
- 7. Marketing authorisation holder
- 8. Marketing authorisation number(s)
- 9. Date of first authorisation/renewal of the authorisation
- 10. Date of revision of the text
PosologyAdults:Premique Low Dose is taken in a continuous combined 28-day regimen of one tablet daily with no break between packs.In women who are not taking hormone replacement therapy or women who switch from another continuous combined hormone replacement therapy product, treatment may be started on any convenient day. In women transferring from a sequential hormone replacement therapy regimen, treatment should begin the day following completion of the prior regimen. For treatment of postmenopausal symptoms: Take one tablet per day. Breakthrough bleeding and spotting may occur in the early stages of Premique Low Dose therapy. If breakthrough bleeding persists and endometrial abnormality has been ruled out, a higher dose of treatment or cyclic therapy should be considered as an alternative.The lowest dose and regimen that will control symptoms should be chosen.
Maintenance/Continuation/Extended treatmentFor initiation and continuation of treatment of postmenopausal symptoms, the lowest effective dose for the shortest duration (see section 4.4) should be used. Patients should be re-evaluated periodically to determine if treatment for symptoms is still necessary.The benefits of the lower risk of endometrial hyperplasia and endometrial cancer due to adding a progestogen should be weighed against the increased risk of breast cancer (see sections 4.4 and 4.8). Forgotten tablet: If a tablet is forgotten, it should be taken as soon as the patient remembers, therapy should then be continued as before. If more than one tablet has been forgotten only the most recent tablet should be taken, the patient should not take double the usual dose to make up for missed tablets. Missed pills may cause breakthrough bleeding.Elderly:There are no special dosage requirements for elderly patients, but, as with all medicines, the lowest effective dose should be used.Paediatric population:Not recommended.
Method of administrationPremique is taken orally.
Medical examination/follow-upBefore initiating or reinstituting HRT, a complete personal and family medical history should be taken. Physical (including pelvic and breast) examination should be guided by this and by the contraindications and warnings for use. During treatment, periodic check-ups are recommended of a frequency and nature adapted to the individual woman. Women should be advised what changes in their breasts should be reported to their doctor or nurse (see 'Breast Cancer' below). Investigations, including appropriate imaging tools, e.g. mammography, should be carried out in accordance with currently accepted screening practices, modified to the clinical needs of the individual.
Conditions which need supervisionIf any of the following conditions are present, have occurred previously, and/or have been aggravated during pregnancy or previous hormone treatment, the patient should be closely supervised. It should be taken into account that these conditions may recur or be aggravated during treatment with Premique Low Dose, in particular:− Leiomyoma (uterine fibroids) or endometriosis− Risk factors for thromboembolic disorders (see below)− Risk factors for estrogen dependent tumours (e.g. 1st degree heredity for breast cancer)− Hypertension− Liver disorders (e.g. liver adenoma)− Diabetes mellitus with or without vascular involvement− Cholelithiasis− Migraine or (severe) headaches− Systemic lupus erythematosus (SLE)− A history of endometrial hyperplasia (see below)− Epilepsy− Asthma− Otosclerosis
Reasons for immediate withdrawal of therapyTherapy should be discontinued in case a contra-indication is discovered and in the following situations:− Jaundice or deterioration in liver function− Significant increase in blood pressure− New onset of migraine-type headache− Pregnancy
Endometrial hyperplasia and carcinomaIn women with an intact uterus the risk of endometrial hyperplasia and carcinoma is increased when estrogens are administered alone for prolonged periods. The reported increase in endometrial cancer risk among estrogen-only users varies from 2-to 12-fold greater compared with non-users, depending on the duration of treatment and estrogen dose (see section 4.8). After stopping treatment risk may remain elevated for at least 10 years.The addition of a progestogen for at least 12 days per month/28 day cycle or continuous combined estrogen-progestogen therapy in non-hysterectomised women prevents the excess risk associated with estrogen-only HRT. Unless there is a previous diagnosis of endometriosis it is not recommended to add a progestogen in hysterectomised women.The reduction in risk to the endometrium should be weighed against the increase in the risk of breast cancer of added progestogen (see 'Breast cancer' below and section 4.8). Break-through bleeding and spotting may occur during the first months of treatment. If break-through bleeding or spotting appears after some time on therapy, or continues after treatment has been discontinued, the reason should be investigated, which may include endometrial biopsy to exclude endometrial malignancy.
Breast cancerThe overall evidence suggests an increased risk of breast cancer in women taking combined estrogen-progestogen and possibly also estrogen-only HRT, that is dependent on the duration of taking HRT.The randomised placebo-controlled trial, the Women's Health Initiative study (WHI), and epidemiological studies, including the Million Women Study (MWS), are consistent in finding an increased risk of breast cancer in women taking estrogen-progestogen combinations for HRT that becomes apparent after about 3 years (see section 4.8). For all HRT, an excess risk becomes apparent within a few years of use and increases with the duration of intake but returns to baseline within a few (at most five) years after stopping treatment. HRT, especially estrogen-progestogen combined treatment, increases the density of mammographic images which may adversely affect the radiological detection of breast cancer.
Ovarian CancerOvarian cancer is much rarer than breast cancer. Epidemiological evidence from a large meta-analysis suggests a slightly increased risk in women taking estrogen-only or combined estrogen-progestogen HRT, which becomes apparent within 5 years of use and diminishes over time after stopping.Some other studies, including the WHI trial, suggest that the use of combined HRTs may be associated with a similar or slightly smaller risk (see section 4.8).
Venous thromboembolismHormone replacement therapy (HRT) is associated with a 1.3-3 fold risk of developing venous thromboembolism (VTE) i.e. deep vein thrombosis or pulmonary embolism. The occurrence of such an event is more likely in the first year of HRT than later (see section 4.8). Patients with a history of VTE or known thrombophilic states have an increased risk of VTE. HRT may add to this risk. HRT is therefore contraindicated in these patients (see section 4.3). Personal or strong family history of thromboembolism or recurrent spontaneous abortion should be investigated in order to exclude a thrombophilic predisposition. Generally recognised risk factors for VTE include, use of estrogens, older age, major surgery, prolonged immobilisation, obesity (BMI > 30 kg/m2), pregnancy/postpartum period, systemic lupus erythematosus (SLE), and cancer. There is no consensus about the possible role of varicose veins in VTE. As in all postoperative patients scrupulous attention should be given to prophylactic measures to prevent VTE following surgery. Where prolonged immobilisation is liable to follow elective surgery, particularly abdominal or orthopaedic surgery to the lower limbs, consideration should be given to temporarily stopping HRT 4-6 weeks earlier, if this is possible. Treatment should not be restarted until the woman is completely mobilised.In women with no personal history of VTE but with a first degree relative with a history of thrombosis at young age, screening may be offered after careful counselling regarding its limitations (only a proportion of thrombophilic defects are identified by screening). If a thrombophilic defect is identified which segregates with thrombosis in family members or if the defect is 'severe' (e.g., antithrombin, protein S, or protein C deficiencies or a combination of defects) HRT is contraindicated.Women already on anticoagulant treatment require careful consideration of the benefit-risk of use of HRT.If venous thromboembolism develops after initiating therapy the drug should be discontinued. Patients should be told to contact their doctors immediately when they are aware of potential thromboembolic symptoms (e.g. painful swelling of a leg, sudden pain in the chest, dyspnoea).
Coronary artery disease (CAD)There is no evidence from randomised controlled trials of protection against myocardial infarction in women with or without existing CAD who received MPA.The relative risk of CAD during use of combined estrogen+progestogen HRT is slightly increased. As the baseline absolute risk of CAD is strongly dependent on age, the number of extra cases of CAD due to estrogen+progestogen use is very low in healthy women close to menopause, but will rise with more advanced age.
Ischaemic strokeCombined estrogen-progestogen and estrogen-only therapy are associated with an up to 1.5-fold increase in risk of ischaemic stroke. The relative risk does not change with age or time since menopause. However, as the baseline risk of stroke is strongly age-dependent, the overall risk of stroke in women who use HRT will increase with age (see section 4.8).
Other conditions• Estrogens/progestogens may cause fluid retention and therefore patients with cardiac or renal dysfunction should be carefully observed. Patients with terminal renal insufficiency should be closely observed, since it is expected that the level of circulating active ingredients in Premique Low Dose is increased. • Women with pre-existing hypertriglyceridemia should be followed closely during estrogen replacement or hormone replacement therapy, since rare cases of large increases of plasma triglycerides leading to pancreatitis have been reported with estrogen therapy in this condition.• The use of estrogen may influence the laboratory results of certain endocrine tests and liver enzymes.Estrogens increase thyroid binding globulin (TBG), leading to increased circulating total thyroid hormone, as measured by protein-bound iodine (PBI), T4 levels (by column or by radio-immunoassay) or T3 levels (by radio-immunoassay). T3 resin uptake is decreased, reflecting the elevated TBG. Free T4 and free T3 concentrations are usually unaltered. Other binding proteins may be elevated in serum, i.e. corticoid binding globulin (CBG), sex-hormone-binding globulin (SHBG) leading to increased circulating corticosteroids and sex steroids, respectively. Free or biologically active hormone concentrations are usually unchanged. Other plasma proteins may be increased (angiotensinogen/renin substrate, alpha-I-antitrypsin, ceruloplasmin). Some patients dependent on thyroid hormone replacement therapy may require increased doses in order to maintain their free thyroid hormone levels in an acceptable range. Therefore, patients should have their thyroid function monitored more frequently when commencing concurrent treatment in order to maintain their free thyroid hormone levels in an acceptable range.• HRT use does not improve cognitive function. There is some evidence of increased risk of probable dementia in women who start using continuous combined or estrogen-only HRT after the age of 65.• There is an increase in the risk of gallbladder disease in women receiving HRT (see conditions that need supervision).• A worsening of glucose tolerance may occur in some patients on estrogen/progestogen therapy and therefore diabetic patients should be carefully observed while receiving hormone replacement therapy.• This product contains lactose monohydrate and sucrose. Patients with rare hereditary problems of galactose intolerance, fructose intolerance, the Lapp lactase deficiency, glucose-galactose malabsorption or sucrase-isomaltase insufficiency should not take this medicine.• Estrogens should be used with caution in individuals with severe hypocalcaemia.
Breast-feedingPremique Low Dose is not indicated during lactation.
Adverse drug reactions (ADRs)The adverse reactions listed in the table are based on post-marketing spontaneous (reporting rate), clinical trials and class-effects. Breast pain is a very common adverse event reported in ≥ 10% of patients.
|System Organ Class
|Very Common ADRs ( >1/10)
|Common ADRs ( >1/100, < 1/10)
|Uncommon ADRs ( >1/1000, <1/100)
|Rare ADRs ( >1/10000, <1/1000)
|Very Rare ADRs ( <1/10000), isolated reports
|Infections and infestations
|Vaginal candidiasis
|Neoplasms benign and malignant (including cysts and polyps)
|Fibrocystic breast changes, Ovarian cancer
|Enlargement of hepatic hemangiomas
|Immune system disorders
|Anaphylactic/ anaphylactoid reactions, including urticaria and angioedema
|Metabolism and nutrition disorders
|Glucose intolerance
|Exacerbation of porphyria; Hypocalcemia
|Psychiatric disorders
|Changes in libido; Mood disturbances
|Nervous system disorders
|Dizziness; Headache; Migraine; Anxiety
|Stroke; Exacerbation of epilepsy
|Exacerbation of chorea
|Eye disorders
|Intolerance to contact lenses
|Retinal vascular thrombosis
|Cardiac disorders
|Myocardial infarction
|Vascular disorders
|Pulmonary embolism
|Superficial thrombophlebitis
|Respiratory, thoracic and mediastinal disorders
|Exacerbation of asthma
|Gastrointestinal disorders
|Nausea; Bloating; Abdominal pain
|Vomiting; Pancreatitis
|Hepatobiliary disorders
|Gallbladder disease
|Cholestatic jaundice
|Skin and subcutaneous tissue disorders
|Alopecia; Acne; Pruritus
|Chloasma/melasma; Hirsutism; Pruritus; Rash
|Musculoskeletal, connective tissue and bone disorders
|Arthralgias; Leg cramps
|Reproductive system & breast disorders
|Breast pain
|Breakthrough bleeding/ spotting, Dysmenorrhea; Breast tenderness, enlargement; Discharge
|Change in menstrual flow; Change in cervical ectropion and secretion
|Galactorrhoea; Increased size of uterine leiomyomata
|General disorders and administration site conditions
|Changes in weight (increase or decrease); Increased triglycerides
|Increase in blood pressure
Breast cancer risk• An up to 2-fold increased risk of having breast cancer diagnosed is reported in women taking combined estrogen-progestogen therapy for more than 5 years.• Any increased risk in users of estrogen-only therapy is substantially lower than that seen in users of estrogen-progestogen combinations. • The level of risk is dependent on the duration of use (see section 4.4). • Results of the largest randomised placebo-controlled trial (WHI-study) and largest epidemiological study (MWS) are presented.
Million Women study Estimated additional risk of breast cancer after 5 years' use
|Age range (years)
|Additional cases per 1000 never-users of HRT over a 5 year period*
|Risk ratio & 95%CI#
|Additional cases per 1000 HRT users over 5 years (95%CI)
|estrogen only HRT
|1-2 (0-3)
|Combined estrogen-progestogen
|6 (5-7)
|#Overall risk ratio. The risk ratio is not constant but will increase with increasing duration on use Note: Since the background incidence of breast cancer differs by EU country, the number of additional cases of breast cancer will also change proportionately.
US WHI studies - additional risk of breast cancer after 5 years' use
|Age range (yrs)
|Incidence per 1000 women in placebo arm over 5 years
|Risk ratio & 95%CI
|Additional cases per 1000 HRT users over 5 years (95%CI)
|CEE estrogen-only
|0.8 (0.7 1.0)
|-4 (-6 0)**
|CEE+MPA estrogen & progestogen
|1.2 (1.0 1.5)
|+4 (0 9)
Endometrial cancer risk
Postmenopausal women with a uterusThe endometrial cancer risk is about 5 in every 1000 women with a uterus not using HRT.In women with a uterus, use of estrogen-only HRT is not recommended because it increases the risk of endometrial cancer (see section 4.4).Depending on the duration of estrogen-only use and estrogen dose, the increase in risk of endometrial cancer in epidemiology studies varied from between 5 and 55 extra cases diagnosed in every 1000 women between the ages of 50 and 65.Adding a progestogen to estrogen-only therapy for at least 12 days per cycle can prevent this increased risk. In the Million Women Study the use of five years of combined (sequential or continuous) HRT did not increase risk of endometrial cancer (RR of 1.0 (0.8-1.2)).
Ovarian cancerUse of estrogen-only or combined estrogen-progestogen HRT has been associated with a slightly increased risk of having ovarian cancer diagnosed (see section 4.4). A meta-analysis from 52 epidemiological studies reported an increased risk of ovarian cancer in women currently using HRT compared to women who have never used HRT (RR 1.43, 95% CI 1.31-1.56). For women aged 50 to 54 years taking 5 years of HRT, this results in about 1 extra case per 2000 users. In women aged 50 to 54 who are not taking HRT, about 2 women in 2000 will be diagnosed with ovarian cancer over a 5-year period.
Risk of venous thromboembolismHRT is associated with a 1.3-3-fold increased relative risk of developing venous thromboembolism (VTE), i.e. deep vein thrombosis or pulmonary embolism. The occurrence of such an event is more likely in the first year of using HT (see section 4.4). Results of the WHI studies are presented:
WHI Studies - Additional risk of VTE over 5 years' use
|Age range (years)
|Incidence per 1000 women in placebo arm over 5 years
|Risk ratio and 95%CI
|Additional cases per 1000 HRT users
|Oral estrogen-only*
|1.2 (0.6-2.4)
|1 (-3 10)
|Oral combined estrogen-progestogen
|2.3 (1.2 4.3)
|5 (1 - 13)
Risk of coronary artery diseaseThe risk of coronary artery disease is slightly increased in users of combined estrogen-progestogen HRT over the age of 60 (see section 4.4).
Risk of ischaemic strokeThe use of estrogen-only and estrogen + progestogen therapy is associated with an up to 1.5 fold increased relative risk of ischaemic stroke. The risk of haemorrhagic stroke is not increased during use of HRT.This relative risk is not dependent on age or on duration of use, but as the baseline risk is strongly age-dependent, the overall risk of stroke in women who use HRT will increase with age (see section 4.4).
WHI studies combined - Additional risk of ischaemic stroke* over 5 years' use
|Age range (years)
|Incidence per 1000 women in placebo arm over 5 years
|Risk ratio and 95%CI
|Additional cases per 1000 HRT users over 5 years
|1.3 (1.1 1.6)
|3 (1-5)
Reporting of suspected adverse reactions:Reporting suspected adverse reactions after authorisation of the medicinal product is important. It allows continued monitoring of the benefit/risk balance of the medicinal product.Healthcare professionals are asked to report any suspected adverse reactions via the Yellow Card Scheme at www.mhra.gov.uk/yellowcard.
Conjugated EstrogensThe active ingredients are primarily the sulfate esters of estrone, equilin sulfates, 17α-estradiol and 17β-estradiol. These substitute for the loss of estrogen production in menopausal women, and alleviate menopausal symptoms.
Progestogen:As estrogens promote the growth of the endometrium, unopposed estrogens increase the risk of endometrial hyperplasia and cancer. The addition of a progestogen reduces but does not eliminate the estrogen-induced risk of endometrial hyperplasia in non-hysterectomised women.
Relief of estrogen-deficiency symptomsIn a 1-year clinical trial (n=2,808), vasomotor symptoms were assessed for efficacy during the first 12 weeks of treatment in a subset of symptomatic women (n=241) who had at least 7 moderate or severe hot flushes daily or 50 moderate to severe hot flushes during the week before randomisation. Premique 0.625mg/2.5mg (conjugated estrogens/medroxyprogesterone acetate) was shown to be statistically better than placebo at weeks 4, 8 and 12 for relief of both frequency and severity of moderate to severe vasomotor symptoms.In two clinical trials, the incidence of amenorrhoea (no bleeding or spotting) increased over time in women treated with Premique 0.625 mg/2.5 mg. Amenorrhoea was seen in 68% of women at cycle 6 and 77% of women at cycle 12. Breakthrough bleeding and/or spotting appeared in 48% during the first 3 months, and in 24% of women during months 10-12 of treatment.
AbsorptionPremique Low Dose contains a formulation of medroxyprogesterone acetate (MPA) that is immediately released and conjugated estrogens that are slowly released over several hours. Following single dose administration of Premique under fasting conditions, the time taken to reach the peak plasma concentration (Tmax) was 6 9 hours and the peak plasma concentration (Cmax±SD) was 149±52 pg/ml and 83± 32pg/ml for the unconjugated estrogens, estrone and equilin, respectively. Peak plasma concentration (Cmax±SD) of 724±475 pg/ml was reached at 2 hours (Tmax) for MPA.When single doses of Premique were administered with a high-fat meal, there was a two-fold increase in MPA Cmax (1830±1050 pg/ml) and AUC was increased by approximately 30%. Food had little or no significant effect on the exposure of unconjugated and conjugated estrogens. These changes to MPA Cmax and AUC after a high fat meal are not considered to be clinically meaningful as the pharmacokinetics of MPA are highly variable and safety of a wide range of MPA doses up to 10mg have been demonstrated.Premique can be administered with or without food.
DistributionThe distribution of exogenous estrogens is similar to that of endogenous estrogens. Estrogens are widely distributed in the body and are generally found in higher concentrations in the sex hormone target organs. Estrogens circulate in the blood largely bound to sex hormone binding globulin (SHBG) and albumin. MPA is approximately 90% bound to plasma proteins but does not bind to SHBG.
BiotransformationExogenous estrogens are metabolised in the same manner as endogenous estrogens. Circulating estrogens exist in a dynamic equilibrium of metabolic interconversions. These transformations take place mainly in the liver. Estradiol is converted reversibly to estrone, and both can be converted to estriol, which is the major urinary metabolite. Estrogens also undergo enterohepatic recirculation via sulfate and glucuronide conjugation in the liver, biliary secretion of conjugates into the intestine, and hydrolysis in the gut followed by reabsorption. In postmenopausal women a significant proportion of the circulating estrogens exists as sulfate conjugates, especially estrone sulfate, which serves as a circulating reservoir for the formation of more active estrogens. Metabolism and elimination of MPA occur primarily in the liver via hydroxylation, with subsequent conjugation and elimination in the urine.
EliminationEstradiol, estrone and estriol are excreted in the urine along with glucuronide and sulfate conjugates. Most metabolites of MPA are extracted as glucuronide conjugates with only minor amounts secreted as sulfates.
|Tablet core:
|Lactose Monohydrate Microcrystalline Cellulose Hypromellose 2208, K100M Magnesium Stearate Purified Water
|Tablet coating:
|Sucrose Microcrystalline Cellulose Hydroxypropyl Cellulose Hypromellose, 2910, E6 Hypromellose, 2910, E15 Polyethylene Glycol 400 Purified Water Eudragit NE 30 D (30% solids) (Ethyl Acrylate and Methacrylate Copolymer Dispersion) Spectrablend Yellow 88101N020 1 Purified Water Opaglos® 2, Clear, 98Z19173 2 Purified Water
|Printing on tablet:
|Opacode® WB NS-78-17821, Black Ink (Purified Water, Iron Oxide Black (E172), Isopropyl Alcohol, Propylene Glycol, Hypromellose 2910)
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realmagick.com The shrine of knowledge.
Muslim Arabs
A selection of articles related to muslim arabs.
Original articles from our library related to the Muslim Arabs. See Table of Contents for further available material (downloadable resources) on Muslim Arabs.
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History & Anthropology >> Arabic
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Muslim Arabs is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Muslim Arabs books and related discussion.
Suggested News Resources
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- When Hillary Clinton threw Arab and Muslim Americans under the bus
- Without hesitation, Clinton condemned her Muslim supporters, returned their donations and refused to meet with Arab and Muslim Americans for the remainder of her campaign, all in the spirit of "wooing Jewish voters," as The New York Times put it.
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- However, Alan Cooperman, director of Religion Research at Pew, told Al-Monitor that overall Arabs in Israel are less religious than in nearby Arab countries.
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- Laying down a heavy critique of the Islamic world, he added: "Arabs have no more creative force. Islam does not contribute to intellectual life, it suggests no discussion. It is no longer thought.
Great care has been taken to prepare the information on this page. Elements of the content come from factual and lexical knowledge databases, realmagick.com library and third-party sources. We appreciate your suggestions and comments on further improvements of the site.
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subset: commoncrawl


text:
By GREGG BELL
AP Sports Writer
SEATTLE — Yes, Marquette is small. Its coach claims "we will
be the smallest team you have seen" from a major conference.
Buzz Williams also says Lazar Hayward, Marquette's center and
leading scorer, "is 6-6 1/2 – with his shoes on."
Quincy Pondexter knows Hayward to be even smaller than that.
Pondexter and Hayward were teammates last summer for the United
States during the World University Games in Belgrade, Serbia.
Both were greeted there by a training table with unrecognizable
native dishes they refused to eat.
"He was losing weight by the day," Pondexter said Tuesday of the
225-pound Hayward, who leads Marquette's four-guard offense in
scoring at 18.1 points per game entering Thursday's first-round
meeting in the NCAA tournament between the 11th-seeded Huskies
(24-9) and sixth-seeded Golden Eagles (22-11).
"I starved a couple days, ate bread, water. It was like fasting.
Then I went ahead and got some McDonald's."
A re-nourished Pondexter has Washington recharged for its second
consecutive tournament appearance.
"He can pretty much do it all," Hayward said of his former dorm
mate in Serbia.
Pondexter has led the Huskies to seven consecutive wins,
including three last weekend to secure the Pac-10 tournament
To make it eight in a row and get into Saturday's second round,
Washington needs to go back inside and find out just how small
Marquette is.
"You want to test them, to see what they can do inside," point
guard Isaiah Thomas said.
Which is to say, the Huskies need to keep playing the way they
have all season while in San Jose. A second-round game would be
against either third-seeded New Mexico or Montana. The Lobos'
tallest starter is 6-8.
Even the 5-8 Thomas will have a height advantage Thursday at
point guard over Maurice Acker, whom Williams says is more like
5-7 1/2 instead of his listed 5-8.
"He's smaller than me?" Thomas said, amazed
So again it's inside or bust for the Huskies. Washington is at
its frenetic best when Thomas, whose average of 17.1 points per
game is second on Washington to Pondexter's 19.8, is driving
daringly into the lane. He floats circus shots or attracts
multiple defenders, leaving Pondexter or revitalized, 6-9
forward Matthew Bryan-Amaning open for easy baskets underneath.
"We always try to be in there going to the paint, getting points
underneath and off offensive rebounds, or to get us to the foul
line," Washington coach Lorenzo Romar said.
One of the reasons the Huskies are in this tournament is because
they got inside then made 17 of 18 free throws in the Pac-10
tournament title game to clinch the win against California. The
automatic bid that came with it eliminated the stress of whether
the NCAA tournament selection committee would choose them.
There are potential pitfalls to Washington's inside job.
Doctors have told Thomas he probably has a broken bone in his
shooting hand. Last year's Pac-10 freshman of the year said
Tuesday that trainers are trying to make a less-bulky glove for
him to wear over the hamate bone on the palm of his left hand.
He's planning to wear that Thursday.
"When I fall, that's when all the pain comes back," he said.
Thomas says the glove he had been wearing since getting hurt on
Feb. 11 at Cal caused him to shoot with too much of his hand on
the ball.
Romar calls it a non-issue, citing how well Thomas has played
with the injury.
It's not like Marquette just got small since bids were announced
on Sunday. Although they lost three of the top eight scorers in
school history off last year's team and were picked to finish
12th in the Big East, the Golden Eagles arrived Monday in San
Jose for their fifth consecutive NCAA tournament.
They have been hardened by 15 games decided by five points or
fewer this season. Marquette has won seven of those. It won
three straight in overtime on the road, lost by one at West
Virginia and by five at top-seeded Syracuse.
"We're going to be facing one of the most mentally tough teams -
if not the most mentally tough team – we've faced all season,"
Romar said. "People keep saying, 'Who do they remind you of that
you've played?'
"No one. They get after it. The things they do on the floor
compensate for their lack of size."


text:
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Welcome to Ioana Hotels! This luxury 5-star ski Sinaia hotel is 0.8 mi (1.3 km) from Sinaia Monastery and 2.1 mi (3.4 km) from Peles Castle. Cantacuzino Castle and Bucegi National Park are also within 9 mi (15 km).
This hotel has its own restaurant serving breakfast, lunch and dinner where you'll find a selection of items to try. The bar/lounge is a perfect place to have a drink.
This hotel has its own restaurant serving breakfast, lunch and dinner where you'll find a selection of items to try. The bar/lounge is a perfect place to have a drink.
A spa tub and a sauna are among the leisure facilities on offer. Free WiFi is provided so you can check your in-box whenever you like.
See all 23 Venere.com reviews
Fantastic service
Tasty breakfast
Delicious food
Great room
TripAdvisor Traveller Rating: 5
From 239 reviews
Ioana Hotels - Sinaia
Hotel Info: 1-877-214-4288from $98
- Luxury Double Room
Also popular with travelers from the USA
At a glance
Key facts
Hotel size
- This hotel has 24 rooms
- This hotel is arranged over 3 floors
- Check-in time 2:00 PM-11:30 PM
- Check-out time is noon
Airport shuttle service is available on request. Contact the property in advance to make arrangements.
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- One child (6 years old and younger) stays free when occupying the parent or guardian's room, using existing bedding
- Free babysitting/childcare
- No pets or service animals allowed
- Free WiFi in public areas
- Free WiFi in rooms
- Airport shuttle (available on request) *
In the hotel
Food and drink
- Free breakfast
- Restaurant
- Bar/lounge
- Room service (during limited hours)
Things to do
- Spa tub
- Sauna
- Playground on site
- Hiking/biking trails nearby
- Ski lessons available nearby
- Ski equipment rental shops nearby
- Downhill skiing nearby
Working away
- One meeting room
- Conference center
- Tours/ticket assistance
- Dry cleaning/laundry service
- Laundry facilities
- Free newspapers in lobby
- Wedding services
- Year Built 2010
- Elevator/lift
- Safe-deposit box at front desk
- Fireplace in lobby
- Television in common areas
In the room
Home comforts
- Minibar
Be entertained
- Cable TV channels
Stay connected
- Free WiFi
- Phone
- Daily housekeeping
Special features
DiningForest Restaurant - This restaurant specializes in international cuisine and serves breakfast, lunch, and dinner. A children's menu is available.
Focus Bar and Lounge - Onsite lobby lounge. Open 24 hours.
Ioana Hotels - Sinaia's small print
Also known as
- Ioana Hotels
- Ioana Hotels Sinaia
- Ioana Sinaia
Only registered guests are allowed in the guestrooms.
Optional extras
Airport shuttle service is offered for an extra charge of RON 80 per vehicle
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.


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Maize Origin Of Maize
A selection of articles related to maize origin of maize.
Original articles from our library related to the Maize Origin Of Maize. See Table of Contents for further available material (downloadable resources) on Maize Origin Of Maize.
- Origin of the Zodiac Signs
- Zodiac is that imaginary belt encircling the earth through which the sun, moon, and the planets pass during the year.
Mystic Sciences >> Astrology
- The Legend of Stonehenge
- Stonehenge has fascinated thousands of people throughout the ages, even today people are still wondering about the origins of the mysterious Stonehenge. Today's scientists and historians are still unable to come to a solid theory of when, why, by whom, and...
Earth Mysteries >> Mystic Places
- Tarot Cards Overview
- Tarot is made up of four suites of regular playing cards, each having 14 pieces of cards. What distinguishes a deck of tarot cards from conventional playing cards is a single card called the Fool.
Divination >> Tarot Cards
- Story of the Celts: The Celts in Britain
- The Celts in Britain [ 27 ] What is obvious when studying the Celts, as when studying anything, is that different experts say different things--there are always men of knowledge who have conflicting views about specifics. The dates of when the Celts came to...
History & Anthropology >> Celtic & Irish
- Astral Beings and Wildlife
- The astral dimension contains a wide variety of what could be called non-physical subtle energy life-forms; or as Carlos Castenada so aptly calls them: inorganic beings. Some of these have a positive nature (nice) and some seem have a negative nature (not so...
Parapsychology >> Astral Projection
- Select Cross-Cultural and Historical Personifications of Death
- This extensive introduction includes some of the more well known, along with some lesser known Death "incarnations", and I use that term loosely, as in many cultures, the Angel of Death can be quite an adept shapeshifter. We have tried to cull...
Mystic Sciences >> Necromantic Studies
Maize Origin Of Maize is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Maize Origin Of Maize books and related discussion.
Suggested News Resources
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- To test whether maize diversity and population structure are shaped by social origin and/or environmental factors, maize collections and common garden experiments with morphological characterization were performed. Four villages were selected: one ...
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- "This is maize," says Salgado, "not sweet corn." Specifically, it's a blue cónico variety grown in the highlands near Atlacomulco in the state of Mexico and the sole ingredient (aside from water) in Salgado's tortillas at Taco Maria.
- Three MIAA football players take home honors at Scholar Athlete Awards Dinner
- Spanellis showed his Wolverine spirit by wearing a maize and blue tie featuring the Michigan logo. "I think this is a great honor," said Spanellis, picked from the North region.
- Botswana: Village On Bank of Okavango River
- Most of the people staying in the village are of Bayeyi origin. History has it that ... The soil was rich and moist-which produced plenty and bountiful harvests more especially maize, sorghum and peanuts, she remembers with nostalgia.
- Food prices soar by 50%
- At the Agbogbloshie market, this paper gathered that a sack of maize, which used to sell at GHC140 as of January last year, now sells at GHC220 while an 'olonka' of gari sells at GHC6.50; it was sold at GHC3.50 a year ago.
Great care has been taken to prepare the information on this page. Elements of the content come from factual and lexical knowledge databases, realmagick.com library and third-party sources. We appreciate your suggestions and comments on further improvements of the site.
Maize Origin Of Maize Topics
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Keep yourself safe from burglaries | Column
According to FBI statistics more than two million homes across the United States are burglarized each year. Victims of burglaries reported an estimated $4.8 billion in lost property in 2011 with the average loss per homeowner being $2,185. Favorite items for criminals to steal are cash, jewelry, guns, watches and electronic devices.
While burglary, by definition, is a crime where there is no direct confrontation by a criminal, almost everyone who has had a home burglarized knows that it can leave a family feeling violated, vulnerable and angry.
Fortunately, there are a number of steps that homeowners can do to lessen their risk of becoming a victim of burglary. Taking the time to "harden" your home against intrusion can decrease the odds of being burglarized. Criminals want to be successful in committing their crime and many will bypass your home if it requires too much skill or time to break into.
The Bothell Police Department (BPD) takes the investigation of burglary cases very seriously. During the last year, BPD has arrested a number of burglary suspects and has, on many occasions, recovered stolen items. We want to be able to identify and return property to the rightful owner but need your help. A few simple things that you can do that will increase the likelihood of getting your property back should your home be burglarized include taking the time to engrave your driver's license number on your larger, valuable possessions, taking a video or photographs of your belongings, particularly your jewelry and other small valuables, and keeping the receipts from your larger purchases. Keep that information in a safe location such as a safety security box. Taking these practical steps will also help you with insurance claims in case of fire or flooding.
The Bothell Police Department believes the security of you and your family is the top priority. Should you find yourself the victim of a burglary or some other crime, call 911. We are here to serve you.
Bothell police burglary tips
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Remember this includes locking your garage door and back door. Burglars know that these doors often the weakest point of entry and provide the most cover from being observed.
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Carol Cummings is the Bothell Chief of Police.
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realmagick.com The shrine of knowledge.
Bertha Bertha Queen Of Kent
A selection of articles related to bertha bertha queen of kent.
Original articles from our library related to the Bertha Bertha Queen Of Kent. See Table of Contents for further available material (downloadable resources) on Bertha Bertha Queen Of Kent.
- Mythic Heroes of Celtic Ireland
- The Celtic mythology of Ireland is best summarized as consisting of four broad cycles. This month's article deals with mythic Celtic mortals, figures who populate the stories in the second and third cycles below. Four Cycles of Irish Mythology Foundation...
Saga of Times Past >> Legend and Prehistory
- Morrighan (the), Morrigan, Morrigu
- ("Great Queen", "Specter Queen", "Supreme War Goddess" or "Queen of Phantoms or Demons") Irish/Celtic. The Dark aspect of the Celtic Triple Goddess. Crone aspect of the Goddess. Great Mother. Moon Goddess. Great White...
Deities & Heros >> Celtic, Welsh, Irish & Brittish
- The Tarot Queens and the Kama Sutra
- '"Being the source of virtue, woman is the best means of reaching heaven. Man's efforts to be virtuous are impossible outside of conjugal virtue... There is no doubt that women are a source of happiness."' Vatsyayana An ancient principle of Indian...
Tarot Cards >> The Minor Arcana
- Persephone
- Persephone had no real title or position in the world of Olympian gods and goddesses.
Deities & Heros >> Greek
- Select Cross-Cultural and Historical Personifications of Death
- This extensive introduction includes some of the more well known, along with some lesser known Death "incarnations", and I use that term loosely, as in many cultures, the Angel of Death can be quite an adept shapeshifter. We have tried to cull...
Mystic Sciences >> Necromantic Studies
- Story of the Celts: The Celts of Ireland
- The Celts of Ireland [ 33 ] The Celts arrived in Ireland by 350 B.C (some say earlier) and they thrive there to this day. A claim might be made that the Celtic Irish are among the world's oldest nationality groups. Despite periods when foreigners tried in...
History & Anthropology >> Celtic & Irish
- The Four Grieving Queens
- These are the Ladies who attended Arthur after his final battle, when he lay mortally wounded, and they are the ones who carried him off to Avalon. Two are mentioned below, Morgan Le Fay as chief amongst them, and Nimue, a Lady of the Lake. The other two are...
Deities & Heros >> Celtic, Welsh, Irish & Brittish
Bertha Bertha Queen Of Kent is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Bertha Bertha Queen Of Kent books and related discussion.
Suggested News Resources
- King Ethelbert: the Christian monarch whose influence is barely acknowledged today
- For the early years of their marriage, Ethelbert and Bertha would have had what we now call a mixed marriage. Queen Bertha's reign in Kent saw the beginning of a Roman Catholic influence on Anglo-Saxon society – it is thought that Bertha persuaded ...
- Pet pug Frank ends up on Tesco mug, as his owner discovered on a visit to
- A Tesco shopper was left gobsmacked after discovering her pet dog had become the face of a novelty mug. Stunned Ania Knapek, 22, spotted two-year-old pug Frank on a stack of the £5 gifts at the supermarket in Westwood Cross. But the health worker won't ...
- 1400 anniversary of King Ethelbert of Kent mass to be held in Ramsgate
- The east Kent king seems generally to have been the dominant ruler. 8) King Ethelbert became a holy man and after his death was venerated as a saint. 9) King St Ethelbert and his wife, Queen St Bertha, are commemorated in Pugin-designed windows in the ...
- Local beauty queen could lose crown over DUI conviction
- MONROE, Wash. -- A local beauty queen who was busted for drunk driving didn't tell pageant officials about her conviction, and she's in danger of losing her crown now that the secret is out. Stormy Keffeler was arrested last April for DUI.
- Security guard shot behind popular Queen Anne restaurant
- Police responded to the scene, the alley behind Peso's Kitchen & Lounge at 605 Queen Anne Ave. N., at about 1:30 a.
Great care has been taken to prepare the information on this page. Elements of the content come from factual and lexical knowledge databases, realmagick.com library and third-party sources. We appreciate your suggestions and comments on further improvements of the site.
Bertha Bertha Queen Of Kent Topics
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The Hound's Ideal Meal
Unlike our previous character themed meals, there was a lot of consensus about the Hound's ideal meal: Nothing fancy, a cheap cut of meat, bitter drinks, and possibly a lemoncake or two for dessert. Kathleen summed it up well, stating that the meal "should be charbroiled, unpretentious, and drowned in a sea of wine".
We liked where a lot of you went with game meat, what with Sandor being a "hound". The subtle poetry of hound and quarry was too appealing to resist. So, game meat it was, and we chose venison and rabbit. True, in our Middle Ages, only the nobility could hunt, but are you about to stand between the Hound and his meal? Didn't think so.
Our grill was recently stolen, right off our porch. Otherwise we'd do a spit roasted rabbit to go with the meal. Barring that, though, we swapped in some oven roasted rabbit legs alongside the venison sausages.
A big question was whether to sear the meat, or no. Personally, we liked the idea, but could see how the Hound might not. So, we hedged our bets, searing the lamb, then hiding the evidence by braising. :) We also liked the idea of lamb, because while Sandor might be a Hound, he's also more than a bit wolfish. Lamb shank it was, then.
Both Kate Quinn and Irian suggested bone marrow, which we loved. It evokes the image of a big mastiff gnawing on a bone in front of the fire, and also ties in with Random's thought that "Joffrey would probably find it amusing to throw his dog a bone." Ours is topped with applewood smoked salt.
For smaller sides, we liked Frank's suggestion of beans thick with molasses, and Duckchick's of sharp cheese with apples, for the Hound's sharp words.
Our final bill of fare: black bread, bone marrow, leg of lamb, venison sausages, rabbit legs, savory beans and sharp cheese, wilted greens, and rustic lemoncakes.
Our Thoughts:
Good Lord. Or the Seven. Or any other deity the Hound probably doesn't believe in…
This is a fantastic meal.
It is obviously very heavy on the meat, but given the fighter's lifestyle that the Hound leads, this makes sense. The three meats- lamb, venison, and rabbit- all give amazingly rich flavors to the meal. Of course, it helps that we braised the lamb and then the rabbit in mead and molasses. The venison sausage already has port in it, so each of the meats has essentially been cooked in/with booze. Even the vegetables have been braised in mead, along with the lamb, so they're incredibly tender and tasty. And the bread! Also made with beer.
The rustic lemoncakes are a much lighter finish to a very heavy meal, and you'll probably only have room for a couple of them.
Our drinks consultant recommends a beer made with juniper to pair with the meat dishes, in the style of a traditional Finnish Sahti. A couple good examples of this are Huvila Arctic Circle Ale and Lammin Kataja. Another interesting pairing would be a rauchbier, such as Spezial and Schlenkerla, given that the smokiness would pair particularly well with the molasses beans and cheddar.
Honorable Mention:
- Chris's suggestion of black and white truffles to represent the duality of his nature (only if you're buying!)
- Wildling, Selkie, and Julia's suggestions of "little birds". We've got something else planned for those, though… ;)
- Irian's list of other cheap meats, including like black pudding, head cheese, ox tongue, lard, goose fat and bacon
- Richard's suggestion of "Black Dog" wines, especially if served on a yellow tablecloth
- roussefolle's wonderful ideas, just exotic enough to be Westeros, amazingly delicious
- Verity's suggestion of Baked Alaska for dessert, first for the irony of a flambe, and also because they can be made to look like a mountain, and the Hound would enjoy symbolically demolishing and devouring a Mountain
20 thoughts on "The Hound's Ideal Meal"
Jose M. Larrinaga says:
In Spain we eat something similar it´s an ancient dish called "Cocido" which there are many versions in different areas. Mainly composed by Pork ham, chicken leg, beef, stuff with chickpeas and carrots and potatos. Remmember Spain is full of castles.
Trinity says:
Damn!!! I want that shank!!! (DROOL)
Tessa says:
No wine pairings!? We know the Hound enjoys a good flagon (or six) of red wine ;)
fluffywarthog says:
I'd be careful on cooking some of those other offal products in booze- tongue will soak up everything it can get!
Shirley says:
"A big question was whether to sear the meat, or no. Personally, we liked the idea, but could see how the Hound might not."
hahaha!! It took me a second to get that one. Excellent meal! Looking forward to the little birds.
Irian says:
I like it. It's a very nice combo – and I'm not only saying that because of the bone marrow! Mead for the braising of the meats sounds like a fantastic idea – I never really thought about that.
Well and the wilted greens give at least a little color. Although they do not look that wilted … *g*
I am looking forward to doing something like this again!
- says:
That looks fantastic! I really like the idea of the venison sausage — and how can you go wrong with three meats!
And I can sympathize with your stolen grill. My bicycle was stolen out of our detached garage because I forgot to close the garage when I came back home with the groceries so it was left open (for maybe like, 2 hours, in the evening before it was even dark). People suck.
duckchick says:
Oh wow, this looks fantastic! Thanks so much for celebrating one of my favorite characters! I really love the idea of the bone marrow, and now I want to know how to make it! Must Google immediately!
John Thompson says:
That looks really good and hearty … I also love the table in the background of the picture.
Janet says:
Littlefinger fans eagerly await what you'll be doing with little birds.
Carcosa says:
looks exquisite! any chances on getting some details re: preparation? or pointing me in the right direction if the individual dishes have been covered previously? i'd love to try and make this myself, but i'm only a journeyman culinarist (i made that up, pretty cool, right?) and don't trust myself to even attempt something like this just off-the-cuff.
Sandy Fox says:
If the Hound was eating on the move quite a lot of this might be done in one pot over the fire. The meats could be done in a fire-pit underneath. I'd probably chop up the suasages and cook them in the beans. I can see Sandor eating them straight out of the pot prior to digging out the meats and taking them straight from the bone.
As for wilted greens? For little birds. :D
Dawn Marie Martin L. says:
How odd that nobody seems to have noticed the lemoncakes inclusion on the menu…..as they're only Sansa's fave dessert ever!! ;-)
Perfectly Houndish meal….excellent taste everybody. Just misses the sour red wine. Salut!
Natalie says:
I see the Hound as secretly kind and tender hearted on the inside. I imagine that he might like to sneak something a little more refined into this meal when no one is looking.
Rumblefish says:
Lemoncakes shouldn't be in this meal. I understand that the folks running the web site like lemoncakes, however in the book they are almost always used as a metaphor for child-like naievety. No way that metaphor fits the hound, and, having read the books, why would Sandor Clegane have a dessert at all? Not everyone loves dessert, and I think a rough and tumble "meat and potatos" type of person would fit into that category.
Rumblefish says:
I've read you're themed meals and do know that you tend to use foods as metaphors for the characters and their personalities in addition to what they would eat, however I still feel the lemoncakes are a miss because of their already established metaphor.
I definitely agree with you that he should have something in his meal to represent his affection for Sansa, so please allow me to present you with an alternative. The Hound often referred to Sansa as a "little bird." I believe something as simple as a cornish game hen, or, if you prefer to go high end an ortolan bunting (which I realize is not likely to be something you can find nor prepare) would satisfy The Hound's affection for Sansa and his "meat and potatoes" personality without adding the fantasy level naivete that lemoncakes tend to represent.
Anyway, I do enjoy this site and appreciate your response to my first post. I am sorry this one is so late.
Rumblefish says:
oops, wrong your…sorry about that


text:
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Transmission Lines:
Issues Associated with High-Voltage Direct-Current Transmission Lines along Transportation Rights of Way
GAO-08-347R: Published: Feb 1, 2008. Publicly Released: Feb 1, 2008.
Additional Materials:
- Full Report:
- Accessible Text:
(202) 512-3000
Office of Public Affairs
(202) 512-4800
Electricity is central to the national economy and the daily lives of many Americans, powering homes, businesses, and industries. Today, an extensive system consisting of more than 150,000 miles of high-voltage transmission lines works to provide reliable electricity service and transport electricity from power plants to consumers. Federal and state entities share responsibility for regulating the electricity system. On the federal level, the Federal Energy Regulatory Commission (FERC) regulates interstate transmission of electricity and wholesale rates, among other regulatory activities. State public utility commissions are generally responsible for regulating retail electricity sales and, in some cases, planning for new power plants and transmission lines. However, as studies have shown, growth in electricity demand has strained the nation's transmission system, resulting in less flexibility to respond to system problems and an increased risk of potential blackouts. These issues have led some to suggest that new lines or other investments in the transmission system may be required to increase capacity and accommodate growing electricity demand. Several companies have recently introduced proposals to build new high-voltage direct-current (HVDC) transmission lines. Some of these proposed lines would follow active transportation rights of way, such as railroads, highways, and pipelines. Some stakeholders have raised concerns about the potential economic, safety, and security issues related to collocating new HVDC transmission lines along transportation rights of way, particularly for nearby residents and consumers of electric power. Given these issues, Congress included a provision in the Implementing Recommendations of the 9/11 Commission Act of 2007 requiring us to assess the siting of HVDC transmission lines along active railroad and other transportation rights of way and report to appropriate congressional committees. In response to this requirement and after discussions with the committees, we examined (1) the role of the federal government in siting HVDC electric transmission lines along active transportation rights of way, (2) advantages and disadvantages of adding transmission lines and using HVDC technology, and (3) benefits and risks associated with the siting of HVDC electric transmission lines along active transportation rights of way.
Historically, the federal government has had a limited role in siting transmission lines. It has generally only made siting decisions on federal lands. State governments, through public utility commissions and other agencies, traditionally approve transmission line siting. However, the Energy Policy Act of 2005 expanded the federal government's role. Specifically, under certain circumstances, FERC now has the authority to approve and issue siting permits for new transmission lines in areas designated by the Department of Energy as National Interest Electric Transmission Corridors (NIETC). However, some stakeholders have expressed concerns about FERC's expanded authority in the national corridors, including how the state siting process will be affected and whether states and the public will be involved in FERC's proceedings. FERC officials told us they expect the review of a transmission line proposal in the national corridors would have little impact on the states' existing process. FERC officials also told us that to the extent FERC receives applications, they expect to consider information from the state siting process as part of their federal proceeding and that states and the public will have opportunities to participate in and comment on the federal siting process. Currently, federal statutes as well as federal and state guidance encourage the collocation of new transmission lines along existing transportation and other rights of way. We identified potential advantages and disadvantages to adding transmission lines and using HVDC technology. According to studies we reviewed and stakeholders we interviewed, adding transmission lines offers potential advantages, including (1) decreased congestion and improved reliability of the electricity system by providing access to additional sources of generation and additional paths for electricity, (2) lower costs for consumers at the end of the line where electricity is received, (3) better utilization of existing power plants and more competitive local wholesale electricity markets, (4) facilitated development of new electricity sources location outside population centers, and (5) facilitated development of renewable energy sources. Stakeholders and studies also identified potential disadvantages of adding transmission lines, including (1) diminished economic or aesthetic values of the land if lines are built above ground, (2) raised electricity prices in areas from where the electricity is being taken, and (3) reduced incentives to identify alternatives that decrease demand (e.g., energy conservation). With respect to the potential advantages of using HVDC over HVAC technology, studies we reviewed and stakeholders we interviewed indicated that HVDC lines generally (1) cost less than HVAC over long distances and (2) allow operators of transmission systems to have more control over the direction and the amount of power flowing over HVDC lines. Potential disadvantages of using HVDC over HVAC technology include (1) higher costs for short-distance lines due to the cost of equipment needed to convert DC into AC electricity used by residents and (2) the lack of electricity benefits to consumers living along these lines--unless converter stations are installed at intermediate locations--because such lines are generally not connected to local electricity lines.
Sep 14, 2016
Nuclear Weapons:NNSA Should Evaluate the Role of the Enhanced Surveillance Program in Assessing the Condition of the U.S. Nuclear StockpileGAO-16-549: Published: Sep 14, 2016. Publicly Released: Sep 14, 2016.
Sep 8, 2016
Department of Energy:Actions Needed to Strengthen Acquisition Planning for Management and Operating ContractsGAO-16-529: Published: Aug 9, 2016. Publicly Released: Sep 8, 2016.
Aug 11, 2016
Nuclear Supply Chain:DOE Should Assess Circumstances for Using Enhanced Procurement Authority to Manage RiskGAO-16-710: Published: Aug 11, 2016. Publicly Released: Aug 11, 2016.
Aug 9, 2016
DOE Project Management:NNSA Needs to Clarify Requirements for Its Plutonium Analysis Project at Los AlamosGAO-16-585: Published: Aug 9, 2016. Publicly Released: Aug 9, 2016.
Aug 4, 2016
Nuclear Waste:Waste Isolation Pilot Plant Recovery Demonstrates Cost and Schedule Requirements Needed for DOE Cleanup OperationsGAO-16-608: Published: Aug 4, 2016. Publicly Released: Aug 4, 2016.
Jul 15, 2016
Nuclear Security:NRC Has Enhanced the Controls of Dangerous Radioactive Materials, but Vulnerabilities RemainGAO-16-330: Published: Jul 1, 2016. Publicly Released: Jul 15, 2016.
Jul 14, 2016
Department of Energy:Whistleblower Protections Need StrengtheningGAO-16-618: Published: Jul 11, 2016. Publicly Released: Jul 14, 2016.
Iran Nuclear Agreement:The International Atomic Energy Agency's Authorities, Resources, and ChallengesGAO-16-565: Published: Jun 9, 2016. Publicly Released: Jul 14, 2016.
Jun 20, 2016
Combating Nuclear Smuggling:NNSA's Detection and Deterrence Program Is Addressing Challenges but Should Improve Its Program Plan [Reissued on June 20, 2016]GAO-16-460: Published: Jun 17, 2016. Publicly Released: Jun 17, 2016.
Mar 3, 2016
DOE Loan Programs:Information on Implementation of GAO Recommendations and Program CostsGAO-16-150T: Published: Mar 3, 2016. Publicly Released: Mar 3, 2016.
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I am quirky, artsy, and weird
My glasses are broken all to hell but it's cause I love them dearly and they quit making the brand and design. I'm stubborn when it comes to things like that.
Movies: Too Many!!! I'm a movie junkie (when I can afford to be) I love movies from when I was a kid like Hook and Neverending Story. I love more mature movies (no, I don't mean "adult films" either) I have a sporadic love of watching the same movie over and over as well. I like movies about mental patients. I love Robin Williams movies. I dig Kevin Spacey and Helena Bonham Carter. I still love Johnny Depp although media makes him overrated. Kate Winslet is amazing too (Go see Eternal Sunshine of the Spotless Mind!). I love musicals. Sometimes the only way you can see them is through film. I love Rent, Hedwig and the Angry Inch, and the Rocky Horror Picture Show. I love The Full Monty and basically almost any British movie. Bone Collector, Man on the Moon, Beetlejuice, Braveheart, Fight Club, Fear and Loathing in Las Vegas, Princess Bride, Mel Brooks movies.. I like SOME movies based on comics like V for Vendetta, X-Men and Ghost World. I love I like movies with realistic depth to them. I dunno. I just like movies lol.
Music: I'm into bands that most of you have barely heard of. I love weird music as well as old cheesy poplar stuff. Ani Difranco is amazing. Collective soul, Goo Goo Dolls, Fiona Apple, Eric Clapton, Scissor Sisters, Pink, Alanis Morsette, Live, Linkin Park, Just Jack it goes on and on and gets more obscure as it goes.. :)
Food: Veggies!! Whole Foods! I go to Green Tree which is a local co-op in Mt-P that I loooove. All organic yum yums. Oh and yes.. i do enjoy junk food and candies. I would'nt have my chubby-bum if not for these lovely items lol.
2. The UK, I want to be there like.. now.. or now..
3. My Pets. A 10 yr old Calico cat and my weird ass ferrets Layla and Jo-Jo
4. Music (yea I know, generic answer, but it does consume my life)
5. My Mac- my poor abused laptop.
6. Green tea (with sage *drool*)
Love thats sailed and gone and the shores yet to come.
Ways in which I can travel more.
How much longer I am here in college
-and- what I am going to do when I leave college
Movie Quotes and music
Also, for the time being, I am only looking for friendships at this point. Not saying a real charmer could convince me otherwise. I am not here for a quick slam, nor am I here for a romance. I'm just here to chat with some interesting people and hopefully make a friend or two. :)
-if you wanna watch The Young Ones, Little Brittan or Mighty Boosh and need someone to huggle.
-you're a long lost friend
-you're a future long lost friend
-if you don't mind being a little stupid and wacky sometimes.


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There Is Peace (Ewe Of Ghana)
Emefa Louw, Emefa Calder, Emefa Middleton, Emefa Wade, Emefa Villiers
If you know people with name Emefa or have name Emefa, please write down your opinion about "What is the meaning of my name Emefa".
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realmagick.com The shrine of knowledge.
Alicya Eyo
- Watch Alicya Eyo say goodbye to Emmerdale viewers in emotional video: ''It's
- The 39-year-old star praised her co-stars, crew and the ITV soap's fans for helping to make her four-year stint on the show "an absolute blast". She said: "It's been incredible. I feel really emotional because it's the end of an era for me.
- Emmerdale's Alicya Eyo reveals devastating pregnancy heartache for Ruby Haswell
- Emmerdale's Alicya Eyo has shed some light on that situation, she said: "Super Dan will continue to help because he just wants the best for them.
- British actress Alicya Eyo on coming out and being a lesbian role model
- 'Some people will see me as a role model. I feel lucky to be in the position I'm in and can speak out about being gay. I do feel I have a responsibility to do that.
- Emmerdale: Alicya Eyo: 'Ruby has to get away after Ali's betrayal'
- When Ruby proposes to girlfriend Ali, she has no idea that her other half is covering up an enormous secret - her one-night stand with Dan that may have left her pregnant.
Alicya Eyo is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Alicya Eyo books and related discussion.
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Good morning! Here is a look at your forecast at the bus stop this morning:
Temperatures: 35-40° for most of central New York, 29-34° for the North Country.
Wind chills: Same as the temperature.
Sky condition & precipitation: Cloudy skies across the entire area. There will be some leftover sprinkles or light rain showers scattered across central or northern New York. Across the Tug Hill Plateau, extreme northern Oneida county and the Adirondacks, the precipitation will likely be light snow.
What should I wear outside?: A fall or winter jacket is a good idea. You might need an umbrella this morning. Of course, it is ultimately your decision on what you think you and your children should wear.
Any notable driving condition issues?: Conditions are mainly wet across CNY. However, sections of the North Country and Adirondacks have a light accumulation of snow.
Special concerns: None
Afternoon ride home on the bus: Temperatures will be in the 48-53° range with cooler readings across the North Country and milder conditions across the southern Tier and Finger Lakes. Winds will be only 5 MPH with negligible wind chill.
You can stay up to date with any severe weather with these links:
Interactive Doppler Radar
Triple Doppler Radar
Lightning Strikes: Lightning Strikes
: (Make sure to hit the 'F5' key to refresh the page.)
Follow CNY Central Meteorologists on Twitter
If you see a severe weather, damaging winds, hail, or flooding, please let us know on Facebook or by e-mail at