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Tourette Syndrome Awareness Day will be fun and educational for everyone
The first annual statewide event put on by the New Jersey Center for Tourette Syndrome will take place Sunday, April 29, with the Somerset Patriots at TD Bank Ballpark in Bridgewater
That is one of the messages the Ledermans hope to convey when they take part in the New Jersey Center for Tourette Syndrome and Associated Disorders' (NJCTS) first annual statewide Tourette Syndrome Awareness Day on Sunday, April 29, with the Somerset Patriots Baseball Club at TD Bank Ballpark in Bridgewater. Lederman recently wrote the following entry on NJCTS' popular parents blog, TSParentsOnline – online at http://www.njcts.org/
"My son slipped off a garage step, tumbled into the recycling bins — scattering cans and plastic bottle tops — and smashed my new cell phone that was in his hand onto the concrete floor. He is fine, the mess is cleaned up, and now when I use my cell phone with the shattered screen, I'm reminded for the 100th time that he has Tourette, that he tends to be clumsy because of this disorder, and that he was feeling only the first of many embarrassments to come throughout the course of his fifth-grade day.
"As parents of kids with TS, we live in homes with cracked phone screens, frequent spills, holes in walls and countless casualties of complex motor tics, scarce impulse control and fits of rage. … We are excruciatingly aware that this disorder is ours, to live with, overcome, research, treat and cure. Perhaps for this reason, I originally deleted from my inbox the notice for the first annual statewide Tourette Syndrome Awareness Day.
"And while I was grateful to NJCTS for getting this amazing event on the calendar, after several years of unrelenting TS symptoms with my son, what I felt I needed was to be a little LESS aware of TS for a day. I changed my mind after my son, frustrated by a barrage of tics, launched a football — whizzing it past my friend's head and nailing the screen door, which jolted with the smack of metal. After my profuse apology, my friend asked, feigning curiosity, 'Now, does he get punished for these things?'
"I'm not angry with her for asking the question, just as I'm getting better at not getting angry when in public we're met with stares and looks loaded with judgment because he's yelled a curse or thrown himself down in the street. I realize now that Tourette Syndrome Awareness Day is not about buying four tickets so my typically stressed-out family can enjoy a baseball game and my son has an opportunity to feel there are others like him and many supporting him — admittedly both wonderful benefits.
"The real importance of this day comes from filling the stands with as many of our relatives, friends, community members and colleagues as we possibly can, increasing our circle of understanding and surrounding ourselves with people who will support us and our children. By getting the official Tourette Syndrome Awareness Day flyer out on Facebook or Twitter, and posting it in your school, church or temple bulletin board, you can increase the chances that those who come into contact with our kids are educated about TS.
"The other real benefit comes from the funds raised from ticket sales that go 100 percent to NJCTS, the group that thankfully NEVER gets pouty, tired or bitter as I was, wanting to take a day OFF from TS awareness. They have done more than anyone to promote understanding, education and advocacy for our kids and community members with TS. So my family and I will be attending Tourette Syndrome Awareness Day, promoting the event heavily, and are challenging all members of our TS family to do the same. We really hope to see you there."
The goal of Tourette Syndrome Awareness Day, which will feature the Patriots playing the Long Island Ducks at 1:05 p.m. (with the gates opening at noon), is to promote advocacy for TS and the programs/services of NJCTS as the only agency in the state and one that leads the nation in supporting the needs of families, professionals and researchers dealing with Tourette.
Prior to the start of the game, there will be on-field presentations in recognition of NJCTS scholarship winners, the Educator of the Year and the Healthcare Provider of the Year. These presentations will begin at approximately 12:40 p.m. Beginning at noon, kids will have the opportunity to take part in a pregame autograph session with the Patriots on the field. The first 1,500 kids in attendance also will receive a Patriots Youth Jersey, courtesy of Raritan Valley Orthodontics. Following the game, kids will be allowed to run the bases in the Diamond Derby.
Tickets to Tourette Syndrome Awareness Day are $10 and available only through NJCTS and can be obtained by visiting www.njcts.org/
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Holmes named Division III Player of the Year by HERO Sports Holmes is selected as the Division III Player of the Year by the website, HERO Sports. Full Story
WBCA and D3hoops tap Holmes an All-American Jordan Holmes becomes the fifth Denison women's basketball player to earn WBCA All-American status. Full Story
Late run sends #14 ONU past Big Red in NCAA first round A 20-8 run over the final 5:17 lifted #14 Ohio Northern past Denison in the first round of the 2016 NCAA Tournament on Friday at Hope. Full Story
Holmes is named to CoSIDA Academic All-America team Jordan Holmes was named to the CoSIDA Academic All-America third-team. She is the 75th Academic All-America from Denison. Full Story
Big Red women to face Ohio Northern in NCAA Tourney Denison will face Ohio Northern in Holland, Mich. on Friday, March 4 in the NCAA Tourney first round. Full Story
More Headlines
March 2, 2016 Jordan Holmes, Sara Lee headline All-NCAC teams
February 26, 2016 Allegheny buzzer-beater stuns No. 23 Big Red
February 24, 2016 Women set to host Gators in NCAC semifinal
March 16, 2016 Holmes named to D3hoops.com All-Region team
play W Basketball
February 26, 2016 DSN Spotlight: Jordan Holmes '17
February 23, 2016 Big Red tops OWU; advances to NCAC semifinals
February 23, 2016 Holmes wins 5th NCAC POW award
February 22, 2016 Women to host Ohio Wesleyan in NCAC Quarterfinals

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John M. Beck is founder and Executive Chairman of Aecon Group Inc. (TSX: ARE), Canada's premier construction and infrastructure development company. A leader in providing services to private and public sector clients throughout Canada and internationally, Aecon primarily serves the Infrastructure, Energy and Mining sectors.
A graduate in Civil Engineering from McGill University, Mr. Beck has more than 50 years of experience in the construction industry in Canada and internationally. His background includes corporate leadership in numerous construction activities including heavy civil projects and public-private partnerships for the development of infrastructure, such as airports, toll roads and transit systems.
Mr. Beck is currently a member of the Board of Directors of PPP Canada, the Ontario Financing Authority, the Royal Conservatory of Music as well as Co-Chair of the Infrastructure & Urban Development Industries at the World Economic Forum. He is a member of the Advisory Council for the School of Public Policy at the University of Calgary and is also a member of the Business Council of Canada. He was previously Chairman of the Board of the Ontario Power Authority, a government agency with responsibility for planning and procuring all of the province's power needs for the next 20 years. He was named P3 Champion of the Year by the Canadian Council of Public Private Partnerships in 2013. In recognition of his distinguished achievements and career-long service to the engineering profession, Mr. Beck was inducted as a Fellow into the Canadian Academy of Engineering.
As President and Chief Executive Officer of Aecon Group Inc., Teri McKibbon is at the forefront of one of Canada's leading construction and infrastructure development companies. Under his leadership, Aecon remains a partner of choice for complex, interdisciplinary mega projects. More than 30 years' experience integrating and managing construction-related companies has provided Mr. McKibbon with demonstrated expertise in, and a comprehensive understanding of, the diversity and complexity of Aecon's operating environment. He has been with the company since 1996. Named to the role of Chief Executive Officer in June 2014, and President in June 2013, Mr. McKibbon has held successive positions within Aecon, including Chief Operating Officer (2011) and Executive Vice President and CEO of Aecon's Infrastructure division (2005). He has been a member of the Executive Committee of Aecon Group Inc. since 2006.
In addition to being a member of the Aecon Board of Directors, Mr. McKibbon is a Trustee of the Northern Property Real Estate Investment Trust, as well as a member of the Canadian Council of Chief Executives. He is a former Trustee of International Union of Operating Engineers, Local 793, Training Trust Fund and of Labourers' International Union of North America (Washington D.C.), and former President of both the Pipeline Contractors Association of Canada and the Ontario Hot Mix Producers Association. He has also served as a Board member of the Ontario Road Builders Association and the Utility Contractors Association of Ontario.
Mr. McKibbon holds his ICD.D designation through the Institute of Corporate Directors and is a graduate of the ICD-Rotman Directors Education Program. He is also a certified Gold Seal Project Manager through the Canadian Construction Association.
Paula Palma has served as Executive Vice President and Chief People and Information Officer (CPIO) since June 2014. Ms. Palma oversees Aecon's vast human resources and information technology functions. Ms. Palma joined Aecon as Chief Information Officer in October 2012, and brings more than two decades of extensive experience in Information Technology and Management Consulting. She held senior executive roles in London and Paris with a variety of world class organizations, including Managing Partner of VPX Consulting, Chief Information Officer and Board Member of VERTEX Data, and COO at ATOS ORIGIN. Ms. Palma received her undergraduate degree at the University of Toronto, completed her MBA at McGill University, and a Global Executive MBA at INSEAD Paris. She is a member of the International Institute of Marketing and Fellowship, the UK Institute of Directors, and the UK Financial Services Authority.
David Smales has served as Executive Vice President and Chief Financial Officer of Aecon since November 2009 and is responsible for financial reporting, accounting and compliance, budgeting and financial planning, taxation, treasury, operational finance, shared services and Aecon's capital markets activities. Prior to joining Aecon, Mr. Smales was the Chief Financial Officer of Catalyst Paper Corporation and prior to that held a number of senior financial positions at Novar plc in the UK, focused on international operations. His career also includes roles in general management, strategy, and M&A both in industry and during 10 years with PricewaterhouseCoopers. Mr. Smales is a member of the Institute of Chartered Accountants in England and Wales and has a BA (Honours) degree from the University of Newcastle-Upon-Tyne in England.
L. Brian Swartz has served as Executive Vice-President of Aecon since June 2012. He has been with Aecon since 1997. Mr. Swartz is Chair of the Aecon Project Review Committee, a member of the Executive Committee and serves on the majority of the boards of directors for its wholly owned subsidiaries. Mr. Swartz has executive responsibility for managing a broad portfolio of corporate services including legal, corporate secretarial, risk management, bonding, office/facility services, and strategic planning services to the Aecon group of companies. He has been actively involved in many major infrastructure and P3 initiatives in Canada and abroad including: Highway 407, Union Station Train Shed Renewal, Union Pearson Express, Ferihegy Airport (Hungary), Cross Israel Toll Highway, Nathpa Jhakri Hydroelectric Power Project (India), Quito International Airport (Ecuador), Pearson International Airport (Toronto), Darlington Nuclear Refurbishment and many other projects. From 1992 – 1997 Mr. Swartz was lead counsel to the Province of Ontario in developing the Highway 407 initiative. In 2013, Aecon's Legal department was awarded the distinction of "Best Canadian Legal Department" by the International Legal Alliance (Paris). In 2008, Mr. Swartz Chaired the Construction Lien Act Committee, liaising between the OBA, OGCA, COCA and the MAG to ensure stakeholders concerns were addressed and amendments were made. He is Past Chair of the Ontario Bar Association, Construction Law Executive. He is a member of the Board of Directors of the Canadian Employers Council and a former director of the Canadian Construction Association. Mr. Swartz is a member of the Editorial Board of the International Journal of Corporate Counsel (London UK). He was recently appointed to the Board of Advisors for Osgoode Hall Law School's Professional Development Program which is creating professional development curriculum for senior in-house counsel. Mr. Swartz earned his LLB from Osgoode Hall Law School in 1981 and in 2003 received a Cert. Arb from University of Windsor Law School and a certificate in Advanced Management from the Schulich School of Business, York University. Mr. Swartz writes and speaks regularly in his areas of expertise and serves as a mentor for the Canadian Corporate Counsel Association's young lawyer mentoring program.


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This poem originally appeared in the March 2010 issue of Poetry magazine
By Mahmoud Darwish
By Dan Gerber
By Neal Whitman
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David Yezzi's poetry collections include Azores (2008) and The Hidden Model (2003), and his criticism and poetry have appeared in The New York Times Book Review, The Wall Street Journal, and Best American Poetry. A former Stegner Fellow at Stanford University, Yezzi is Executive Editor of The New Criterion. He has also edited The Swallow Anthology of New American Poetry (2009). His libretto for a chamber opera by composer David Conte, Firebird Motel, premiered in 2003 and was released on CD by Arsis (2007). Poet-critic Adam Kirsch, who selected Azores as one of Slate's Best Books of 2008, noted that Yezzi's poetry "displays a civilized mastery reminiscent of Philip Larkin and Donald Justice, which no poet of his generation can match." David Yezzi is a graduate of Carnegie-Mellon University and received his MFA from Columbia University.
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Daisy Fuentes is well on her way to creating a chain of fragrances.
Fuentes, whose Dianoche scent project for Kohl's Corp. quickly became one of the retailer's top-selling fragrances after its launch last July, will add So Luxurious, a new women's juice, in July.
And the budding fragrance creator can't contain her excitement. "When I got my first TV job, I was actually in cosmetology school," said Fuentes in an exclusive phone interview Monday. "I was going to be the next Vidal Sassoon. I'm a huge product junkie. I have more products than anyone in the world, and I've always said things like, 'If this had a little less of this, or that applicator was a little different….' And now people are listening to me and actually changing things to reflect what I'm saying. It's great!"
Fuentes is completely hands-on with her beauty business, in fact. "This has been the most fascinating part of my career," she said. "The whole beauty thing is a joy."
Created by Fuentes, working in collaboration with International Flavors & Fragrances and Karyn Khoury, senior vice president of corporate fragrance development worldwide for the Estée Lauder Cos. Inc., So Luxurious has top notes of wild honeysuckle, beach flower accord, mandarin and watery quince; a heart of magnolia, orange flower and Living Glorious Flower of Cuba accord, and a drydown of driftwood, amber and honey. "So Luxurious actually has its roots in the development process for Dianoche," said Fuentes. "It was born from a finalist for Dianoche. In the final process, we came up with two scents which we loved equally. We went with the other, but when we decided to do So Luxurious, it became the base we built on."
The Living Glorious Flower of Cuba accord is a nod to Fuentes' Cuban heritage and is a rich white floral with a green note and a hint of vanilla, explained Khoury.
"Daisy is the type of woman who wears jeans and diamonds together — she's casual and elegant," said Julie Howard, senior vice president of global marketing and brand development for BeautyBank. "We wanted to reflect that in the packaging, which is a faceted round shape and is very elegant." The bottle was inspired by a ring Fuentes wears everywhere, she added.
This story first appeared in the June 15, 2007 issue of WWD. Subscribe Today.
A 2.5-oz. bottle will retail for $42.50. While none of the executives would discuss sales figures, industry sources estimated that So Luxurious would do at least $5 million at retail in its first year on counter. It will be available in Kohl's 834 U.S. doors.
The fragrance will be promoted in Kohl's ads, in-store merchandising and via a to-be-determined number of vials on cards, added Howard. Fuentes will likely make personal appearances touting the fragrance.
Are the Dianoche and So Luxurious users different? Fuentes doesn't think so. "We all have so many aspects of ourselves," she said. "One of the beautiful things about being a woman is that you can change whatever you like as long as your values stay the same. You can be elegant one day and sexy the next."
"We're setting out to win Daisy a FiFi award," said Jane Hudis, president of BeautyBank, of So Luxurious. Fuentes' Dianoche was nominated this year, but the trophy was taken by BeautyBank's American Beauty Wonderful Indulgence. "Not only is Daisy a superstar, she is a superstar in the Kohl's world. She has a great business that reaches from apparel to many different categories. From the minute that Dianoche hit counters last year, it was a bestseller. We expect equally great things from So Luxurious. We see Daisy, in the broadest sense of the word, as being a big brand — and we will be venturing into other categories with her."
While Hudis wouldn't elaborate, that likely means a move into color cosmetics; the Fuentes beauty brand dipped its toe into those waters with a limited edition color palette in spring 2006.
Fuentes is already hard at work on her next several fragrances and is particularly enamored of a violet scent she's creating. "It reminds me of a baby cologne that my mom used on me —it's a scent that many Latina mothers use on their babies — called Violet Water," she said. "It will be a light, almost-cologne type of scent that is so light and airy and young. I think it will bring out the baby in every woman."
When she's not working on her beauty projects, Fuentes is filming a new series called "The EcoZone Project." The syndicated reality show's premise is heading into celebrity homes and making them "green." So far, said Fuentes, she and her team have made over the homes of Allison Janney and Ron Livingston.


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US: Vice President Joe Biden calls same-sex marriage 'the issue of our day'
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While I guess it's fair enough that he is making a point and going on the record (so many politicians will squirm off the hook so they have credible deniability) I don't know that I can agree with the sentiment.
I think there is a bigger and more important battle to come – Most notably federal recognition of LGBT people as a protected group, and a modern iteration of the Civil Rights Act 1964 that will outlaw, once and for all, acts of discrimination.
I get that repealing DADT was a start, and marriage plays a part, as will anti-discrimination workplace laws currently being worked on (again, ENDA has failed to pass for many years) in that they all function to adjust the cultural zeitgeist and make bigotry less socially acceptable. It's a slow process. And it is federal recognition that truly matters.
Put simply – With a virtually statistically irrelevant number of exceptions all LGBT people will work, all will purchase goods and services. All need to be protected.
Once again, Valksy ,you are "Spot On!
I thought it was transgender issues. Maybe he changed his mind.
I was thinking the same thing. I wonder how many different issues he's said this about now.
LGBT people are not protected in Africa and in some parts of the world.
The molestation, discrimination and murder of LGBT in Africa is rampant, what would the two big countries like United Kingdom and the United State of America would do to stop that at once, to STOP the KILLING of LGBT people.
Who are we as human beings if we ignore the suffering of others?
Mohamed Salieu Kamara- THANK YOU ! I don't like the unbalanced media in Our World ! Our main focus is towards ourselves, WE in the "Western society" must first and foremost improve our situation, forgetting those who suffers much more–THAT is very obvious if one look at the situation for LGBT PEOPLE in Africa and Asia. To a large degree they are pushed into the shadows. I wish we could judge ourselves more from what we do to others, and get rid of some selfishness.
You make an important point Mohamed.
It seems for every step we make forward in terms of human rights, there is a backlash somewhere else and LGBT suffer.
Joe Biden is a kind and decent man and a true statesman. His support and that of Barack Obama and the entire adminstration is gold.
He wants to have a chat to Shirley Williams!
His stance on marriage equality is commendable and it may be the current battle being fought but the actual issue of today, yesterday and tomorrow is homophobia.
Good man. The UK and US have got the best leaders at the moment they've had for a long time. Blair was good until he went into 'I've had power for too long so now I've gone mad syndrome'.
Does it not depend how you quantify good.
Blair was certainly a good showman and persuader.
However, over time, and to this day, he has repeatedly demonstrated incredible poor judgment.
He is the type of person that has the capacity to lead a group of followers over a cliff.
I totally 300 percent agree with him!
However Congress must pass ENDA first, then the RFMA ("Respect for Marriage Act" that will repeal DOMA)!!!!!
Civil marriage is very important in society for long term stable loving relationships – regardless of what sex of the spouses or partners are!!!!!
Here in Australia we still have 1961 laws on marriage that are just completely out of date and must be updated and reformed – but then again that will never happen under a bigoted and hateful Catholic Church asslicker Tony Abbott Conservative right-wing Tory or Coalition Government!!!!!
These comments are un-moderated and do not necessarily represent the views of PinkNews. If you believe that a comment is inappropriate or libellous, please contact us.
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I am sick with a cough that won't let me sleep at night. I don't have insurance. My sister brpught me some of my nephews cough surup called albuterol sulf 2mg/5mlsyrp. I don't have any idea how much to take or if it will let me sleep. Do you?[:0]
Is Albuterol Sulfate for coughs?
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- Active
- 19 Mar 2011
- Topics
- cough, albuterol
Responses (3)
albuterol sulfate is a drug that is used to break up mucus in the lungs, it is not a cough suppresant. Unless you have pnuemonia or bronchitis or RSV or something like that, it really won't do you any good to take it. It is used over a short period of time to clear the lungs.
I have a chronic cough problem the Dr thinks is asthma that developed from GERD and one of things I have is an Albuterol Sulfate inhaler that is supposed to open up my bronchial tubes when I have an asthmatic coughing attack... only it doesn't always work very well for me. I believe it is a steroid? It will not stop a cough per se; it is supposed to free your lungs from the constricted bronchial tubes so you can breathe again. It is a short term thing. Not complete solution to a chronic cough... you have to find the cause. Many chronic cough are caused by gastric reflux I am told by the Dr.
Further Information
- Albuterol Information for Consumers
- Albuterol Information for Healthcare Professionals (includes dosage details)
- Side Effects of Albuterol (detailed)
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Does albuterol sulfate have a steroid in it?
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One of the most rewarding things about having a successful business is the ability it provides to contribute philanthropically. We are thrilled to announce the launch of the Hanky Panky Supports PeaceLove collection for Summer 2016. When we met Jeffrey Sparr and … Continue reading
Posted in Hanky Panky Products, Philanthropy, Uncategorized Tagged Collaborations, Gale Epstein, Lida Orzeck, PeaceLove Studios, Signature Lace, Summer 2016 Comments Off on Create Peace of Mind™
Introducing mileSTONES by Hanky Panky
Some days are worth remembering. Hanky Panky's newest personalization feature, mileSTONES allows you to commemorate special days with a crystal appliqué of a 6 digit date with slashes. Our personalized mileSTONES panties make ideal gifts for weddings, anniversaries, birthdays, graduations, lease-signings, business launches, real estate … Continue reading
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Hanky Panky Spring 2016: In Bloom
fresh hues Hanky Panky's Spring 2016 color story is an updated mix of bright pop colors and saturated pastels. The Signature Lace palette consists of Allure, a bright, saturated coral-pink, Lip Gloss, a rich pink, Sweet Mint, a lush green, … Continue reading
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For an inside view on the dynamic duo behind Hanky Panky, check out this recent article on Forbes.com: "How The Women Behind Hanky Panky Launched A Brand That Sells An Average Of One Panty Per Second." Of Hanky Panky's signature … Continue reading
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Snuggle Up With Supima® Cotton Sleepwear
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The Art of Gifting Panties
As I rush around finding last minute gifts, I can't help but think of my mother. She had a gift for finding the right gifts, and made every present special by wrapping it in festive paper and a bow. With seven children, … Continue reading
Posted in Hanky Panky Products, Promotions and Specials, Uncategorized Tagged Anne, Boyshorts, gift, gifts, Holiday, packaged, panties, party, thongs, wrapping Comments Off on The Art of Gifting Panties
Simple Gifts
There's a trend towards achieving simplicity in our lives; reducing the amount of stuff, retaining only what we need and value. There is so much competition for clutter in our space and in our minds that many of us long … Continue reading
Posted in Arts & Culture, Music, Uncategorized Tagged Gale, gifts, Music, Shaker, simple, Simple Gifts, simplicity Comments Off on Simple Gifts


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Welcome to Lynn's woodwind department. In addition to our world-renowned faculty, the thing that sets Lynn's woodwind program apart from other conservatories and performance-based institutions is our intimate studio size. All students enrolled at Lynn perform in ensembles from the very first day. Whether you are an incoming freshman, or a second-year graduate student, you will fully participate in all of our ensembles, including orchestra, wind ensemble, woodwind orchestral repertoire class, woodwind chamber ensemble, as well as smaller chamber groups. We have multiple opportunities for individual performance as well; mock auditions, juries, weekly performance forum in front of students and faculty, performance in individual studio classes, as well as combined woodwind studio class. From building a strong musical and technical foundation to taking the finals steps toward winning an audition, Lynn is an extraordinary place to be.
-Dr. Eric Van der Veer Varner
Eric Van der Veer Varner, Woodwind Department Head, Associate Professor- Bassoon
"My objective as a teacher is to help students to become well-rounded musicians in addition to being superlative performers. The bassoon is merely the vehicle through which they will develop their own skills as complete musicians. The pedagogical approach and compact size of the bassoon studio are specifically designed to aid students' mastery of their instrument's technical aspects, with bi-weekly lessons, studio class and reed instruction. The focus and effort you will learn to demand of yourself at Lynn is considerable, but the rewards are incalculable."
Jeffrey Khaner, Artist-in-Residence - Flute
"The opportunity that Lynn University provides students is unique and combines the experience of the elite conservatory with that of a university."
Joseph Robinson, Artist-in-Residence - Oboe
"Lynn University offers highly motivated pre-professional oboists an ideal environment for pursuit of their dreams. As one of Marcel Tabuteau's last students, I follow the tradition of his American School of Oboe Playing. Generous scholarships, talented colleagues and a beautiful campus all enhance the educational opportunity for oboists at Lynn."
Jon Manasse, Artist-in-Residence - Clarinet
"Lynn has created a uniquely superb environment for developing one's talent. For those lucky enough to be a part of this community, the benefits are considerable!"
Highlights in the Woodwind curriculum
- Lessons and Studio Class with Artist Faculty
- Woodwind Chamber Music Coaching
- Orchestral Repertoire Class
- Weekly Performance Forum
- Combined Woodwind Studio Class & Performance Forum
- Lynn Philharmonia Concerts
- Wind Ensemble
- Concerto Competition
- Woodwind Chamber Ensemble
- Mock Auditions
Recent and upcoming master classes
- Gabriel Beavers: Professor, University of Miami
- Jefferson Campbell: Professor, University of Minnesota-Duluth
- Martin Kuuskman: International Soloist
- John Miller: Retired Principal, Minnesota Symphony Orchestra
- Susan Nelson: Professor, Bowling Green State University
- Saxton Rose: Professor, University of North Carolina School of the Arts
- Staci Spring: Professor, Stephen F. Austin University
- Mark Timmerman: New York City Ballet
- Cally Banham: English Horn, St. Louis Symphony
- Jared Hauser: Professor, Vanderbilt University
- Nancy Ambrose King: Professor, University of Michigan
- Igor Leschishin: Principal Oboe of the Kennedy Center National Opera
- Nora Lewis: Professor, Kansas State University
- Nermis Mieses: Professor, Bowling Green State University
- Keisuke Wakao: Associate Principal Oboe, Boston Symphony
- Phillip O. Paglialonga: Professor, Virginia Tech University
- Nadine Asin: Faculty, Bard College, Julliard School (Former Piccolo with the Metropolitan Opera Orchestra)
- Nestor Torres: Grammy-Award Winning Jazz and Latin Flautist
- Adam Workman: Flutistry Boston


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Problem when running luncher
1 Attachment(s)
Hello everyone
its my 1st time posting a technical issue problem in here, I hope you would be able to help me out.
I bought a new laptop and when I installed TO first time it was working fine, but later on i started downloading a lot of games some online and some offline ones. then when I decided to go back to TO I encountered this problem when running the launcher then it closes on its own...:/ in other words, I can't even get to the launcher
I put my SS in the attachment >< hope you guys help me get over this problem
Looks like your Trickster.exe & Trickster.Bin are corrupted, try and get a new 1, if you need a new one, just send me your hotmail email adress so I can upload it to my skydrive, then you can download it from there.
I've got SIMILIAR problems, my launcher works fine for an amount of time and after that, a error window pops out and says "Could not retrieve update list from website" and den when the error window closes, the launcher fails to work. Any help?
Only time I ever get that message is when my wireless drops out and I'm trying to connect to trickster ^^
Sorry for the late reply
Sure that might help
here is my email
Ok I uploaded the main files but not the data folder since its 4GB, try the main files first & see if your client still has errors, if you need the data folder let me know, good luck patching.
umm brother Kheos
where did you upload them? I don't see anything in your post nor in my Email.
I am waiting for your response
You need to open your skydrive account, then click on myfiles, look for a shared folder then download the files there.
Sorry it was the first time for me hearing about "Sky drive" so I didn't have clue about what you were talking about.
but I figured it out later, and I have found your uploaded files in there..and I copy and replaced with my current Trickster Online file but...
nothing worked, still same errors :/
any other solutions..? ><
Are you running TO as an Administrator try doing that if it does not work, you will need to delete your whole TO folder & reinstall again, let me know what happens after that good luck reinstalling ^^
sorry for the long absence...I had many troubles rl ><
anyways kheos I have tried it with run as adminstrator but that didn't fix it and I have also deleted the game and reinstalled it and yet still the excat same problem :/
i have a feeling that the game is having a conflict with one of the games that i have installed..but I don't wanna delete them till I confirm it, cause I tried Trickster on my old laptop and that one doesn't have any games installed and it didn't give me those errors...but on my main good laptop it keeps giving me those for some reason ><;
anyone could help me confirm? :(
*sigh* I really want to log in TO so bad T.T is there none at all who knows the problem with this error? ;_;
Ok I uploaded a text file on my Skydrive, read the instructions after opening the file, let me know what happens after this, the file name is "Update Fix For TO" Good Luck.
ok I have solved the problem on my own and i am back online on TO :) thanks Kheos for your support though and everyone who tried on this thread!
The solution for anyone who encountered this error is below :
there is a problem with the trickster fullpackinstallation you got, so just uninstall it and remove all its files completely from the computer then download the one in Cait's thread (even though the one I downloaded before and got these errors from was the one in their official site...funny how theirs is filled with errors)
Trickster Online Direct Download 2012 (FullPakTrickster.exe) - Trickster Online Revolution
After downloading one of the options packs there, i installed normally without any problems and went into the game xD;
thought i'd encounter some of the GG errors...but amazed that nothing of the sort happend
Thanks again for everyone's help, this topic is solved^^
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Bob's Burgers
Season 6
The Gene & Courtney Show
Gene and Courtney get their big break when they are asked to be the new hosts of the morning announcements, but their romantic history threatens to get in the way. Meanwhile, Tina's attempt to play Cupid goes tragically awry when she volunteers to spearhead the Valentine's Day carnation fundraiser.
Season 3
Ear-sy Rider
A biker gang hangs out at Bob's Burgers as they mourn the loss of their beloved leader "Horny Dave." Meanwhile, Louise has an identity crisis when her bunny ears are stolen and everyone - including the biker gang - rallies around her.
Bob Fires the Kids
Bob worries he's depriving his children of their summer vacation by making them work at the restaurant, so he fires them. However, the kids become so bored with their newfound freedom that they secretly get hired by a pair of married hippie farmers, who hire the Belcher kids as "weed pickers." Meanwhile, Bob hires Mickey the bank robber to help out at the restaurant, but soon regrets his decision.
Mutiny on the Windbreaker
When Bob is invited to be a private chef on a docked cruise ship, he brings the family along to witness his skills outside of the restaurant. However, Bob's big day goes awry when the ship departs with the Belchers on board, and there is no one tending to the restaurant.
The Deepening
In an homage to Jaws, Bob's landlord and pier proprietor Mr. Fischoeder buys a mechanical shark as a pier attraction, but when it turns wild and starts terrorizing the town, it's up to Bob and the family to stop it.
Season 2
Moody Foodie
When the restaurant receives a bad review from a food critic, the Belchers fear that the negative press will keep customers away. When Bob shows up at the critic's house for a redo, his plan quickly spirals out of control when the kids and his fellow restaurant owners show up to support him.


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STORRS, Conn. – Center Keith Gray took a second Tuesday afternoon to ponder what it meant for Duke to enter this weekend's contest with a 20-game losing streak.
Edsall not emphasizing Duke streak
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Flights to Leon from Monterrey
Flights to Leon from Monterrey
Flights Monterrey - Leon fly from Monterrey to Leon at the best prices in the market. Flights from Monterrey (Monterrey) to Leon (León) with Destinia. To search for availability and reserve your flight Monterrey - Leon look at the box above and select the departure and return date as desired. You can also buy several airplane tickets Monterrey (Monterrey airport) - Leon (León airport) at the same time, by selecting the adults, children and babies travelling. You can filter the type of flight if you only want direct flights to Monterrey - Leon, multiple destinations or flight stopovers.
Monterrey and Leon are 525 kilometres away from each other, with an estimated flight time of 00:45 h (this may vary depending on the weather or air routes)
Airports near Leon
Leon has one airport: León (BJX), located 25 km away from the city centre. The hotels in Leon closest to its airport are:
All Leon airports
Top destinations in Mexico
Book your flights now from Leon (Mexico) to the most important cities in the world. The box below contains flights from Leon (Mexico) to the most important cities.
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realmagick.com The shrine of knowledge.
- What is Mushaf Fatimah?
- The most prevalent question about this Mushaf, the most tumultuous and confusing issue is, "What exactly does "Mushaf" mean?" The assumption is that this Mushaf is a special type of Quran.
- Blac Chyna Just Leaked Rob Kardashian's Snapchat Username -- But 'Don't Be
- It looks like Rob Kardashian has officially joined Snapchat! On Monday, the reality star's new lady love, Blac Chyna, took to her own snap story to release her beau's username on the photo-sharing app! Related: Blac Wants You To Mind Your Own Business!
- Khawarij Ideology, ISIS Savagery: Part II
- Shaykh al-Islam Ibn Taymiyyah wrote: 'The Prophet ﷺ ordered us to obey leaders who were both present and well-known (al-a'immah al-mawjudin al-ma'lumin); those who wield executive political authority and have the capability to address the political ...
- Public make their points on Mawlid debate between Dawah Man and Imam
- A debate about celebrating the birthday of the Prophet Muhammed has reached new heights or lows depending upon how you see it. A heated debate between Imran ibn Mansur also known as Dawah Man and Imam Muhammed Asim Hussain has been ...
- Kenya in uproar over speculation Obama may address gay rights
- But as the sun set and they prepared to head home, organizer Immah Reid warned them to be cautious in the coming week. "It's a very agitated space right now," she told the Monitor earlier in the week.
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Holiday Home Piè di Costa.
Holiday home Piè di Costa is located in Tuscany, in the heart of the green hills of Chianti. It is located only 500 meters far from the village of Montaione, an old and typical little town of Tuscany situated in the province of Florence.
Thanks to a favourable geographical position, Montaione is the right place where to stay for those who love a cultural holiday to reach from here the most important cities of art of Tuscany, like Florence, Siena, Lucca and Pisa (which are 50 kilometers far from vacation home Piè di Costa) and San Gimignano and Volterra; it is possible to reach these two cities by car, in about 30 minutes.
Vacation rental Piè di Costa is the ideal place to spend a holiday in Tuscany in every period of the year. Thanks to a height of 270 meters above sea-level, the climate is not so hot even during summer holidays, thanks to the winds which come from sea. However, it is possible to have a bath and swim in the swimming-pool of the vacation home, which is placed in the olive-grove near the house; from here, it is possible to admire the very beautiful landscape of the Tuscany countryside and the hills which overhang Florence.
Vacation home Piè di Costa is an old and local Tuscan farmhouse, whose restructure was finished in 1999 and which was divided in 5 self catering apartments.
All the apartments have been restructured and furnished according to the old tuscan style and tradition, and they perfectly fit the different needs of our guests. There is the romantic apartment for two people and the one with two bedrooms and two bathrooms for a family with children or simply for some friends who are travelling together.


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Royal Crescent Hotel - Bath
A health club, free valet parking and a restaurant are featured at this hotel. Escape the stress of everyday life at The Spa and Bath House, offering facials and detox wraps, as well as hot stone massages, reflexology and body treatments. Guests can also enjoy drinks as there is a bar/lounge. In addition to the on-site spa, a Turkish bath/hammam and a sauna are among the leisure facilities on offer. If you want low-key dining options, you will be pleased to find a picnic area and 24-hour room service. Free WiFi is provided so you can check your in-box whenever you like.
Royal Crescent Hotel - Bath
Hotel Info: 1-877-214-4288from $257
- Deluxe Room
- Classic Room
- Master Room
- Deluxe Room
- Deluxe Suite
- Suite ( Master)
- Classic Suite
- Superior Classic suite
- Classic Suite
- Single Room
- Deluxe Suite
- Deluxe Suite
- Master Suite
- Deluxe Room
- Suite
- Classic Suite
- Suite
- Deluxe Suite
- Classic Room
- Classic Room
- Deluxe Room
Also popular with travelers from the USA
At a glance
Key facts
Hotel size
- This hotel has 45 rooms
- Check-in time 3 PM-midnight
- Check-out time is noon
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- Free babysitting/childcare
- Pets allowed (dogs and cats only) *
- Specific rooms only *
- 2 per room
- Free WiFi in public areas
- Free WiFi in rooms
- Free valet parking
In the hotel
- Free breakfast
- Restaurant
- Bar/lounge
- 24-hour room service
- Coffee/tea in a common area
- Health club
- Full-service spa
- Spa treatment room(s)
- Fitness classes on site
- Pilates classes on site
- Yoga classes/instruction on site
- Bicycle rentals nearby
- Golfing nearby
- Hiking/biking trails nearby
- Steam room
- Sauna
- Conference space
- One meeting room
- 24-hour front desk
- Concierge services
- Limo or Town Car service available
- Dry cleaning/laundry service
- Laundry facilities
- Free newspapers in lobby
- Luggage storage
- Wedding services
- Multilingual staff
- Porter/bellhop
- Elevator/lift
- Safe-deposit box at front desk
- Garden
- Picnic area
- Library
- Fireplace in lobby
In the room
- In-room climate control (air conditioning)
- Air conditioning
- Bathrobes
- Slippers
- Iron/ironing board (on request)
- Hypo-allergenic bedding available
- Blackout drapes/curtains
- Soundproofed rooms
- Turndown service
- Individually decorated
- Private bathroom
- Shower/tub combination
- Designer toiletries
- Hair dryer
- Satellite TV channels
- DVD player
- Desk
- Free newspaper
- Free WiFi
- Phone
- Daily housekeeping
- In-room safe
Special features
On Site
- Health club
- Sauna
- Steam room
- Fitness classes on site
- Pilates classes on site
- Yoga classes/instruction on site
- Bicycle rentals nearby
- Golfing nearby
- Hiking/biking trails nearby
Awards and affiliations
- The property is a member of Relais & Chateaux.
Royal Crescent Hotel - Bath's small print
Also known as
- Crescent Royal Hotel
- Hotel Royal Crescent
- Royal Crescent
- Royal Crescent Bath
- Royal Crescent Hotel
- Royal Crescent Hotel Bath
For bookings of 4 nights or more, cancellation is allowed until 4 PM, 7 days prior to arrival to avoid the charge of 3 nights including tax. No-show fee is 3 nights including tax. For more details, please contact the office using the information on the reservation confirmation received after booking.
Pet-friendly rooms can be requested by contacting the property at the number on the booking confirmation.
Mandatory fees
Pet deposit: GBP 35.00 per stay
Optional extras
Rollaway beds are available for an additional charge
Pets are allowed for an extra charge of GBP 35 per pet, per stay (maximum GBP 60 per stay)
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.


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How Could Sephora Improve its Content Strategy on Instagram? Segmentation.
In our earlier posts about how brands perform on Instagram, we looked at the tactics that leading brands like Starbucks and BMW are using to engage with their followers and grow their communities on the platform. While having an intimate knowledge of these strategies is indispensable, how can we determine which content should be used… Continue Reading


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There are so many brilliant ways to use building blocks in your home or classroom that I thought I might take a few minutes to highlight some of them.
Archives for May 2014
The preschool art gallery
Throughout part of our school year, we began saving a few pieces of the children's artwork so to have a sampling of each child's work that we could display in our simple preschool art gallery… It is always amazing to me how different artwork looks once you frame it or mount it on a colored background. […]
10 playful ways to transform a pizza box
Today I am sharing with you 10 playful ways to transform a pizza box for your preschool classroom…
DIY Memory Box
Since my Pre-K children will be moving on to a new school, we have been enjoying exploring some of our favorite memories and playing some memory games too!
Ten terrific ways to get the most out of water play
Discover these terrific tips for how to get the most out of water play!
Popsicle patterns, lines, and designs in preschool
Stop on by and check out our exploration of popsicle patterns, lines, and designs in our preschool classroom!
Popsicle watercolor paint for preschool
A wonderful exploration of color, smell, taste, and creativity using one simple ingredient! Popsicle Paint!
Inspiring outdoor playscapes
Sometimes, it is hard to think of ideas to spruce up your outdoor play area. With summer just around the corner, I wanted to share some child-friendly backyards and outdoor playscapes that I find to be so inspiring… Turn your screened-in porch into an outdoor studio If you have been following us for awhile, you […]
Simple child made discovery bottles
My students enjoy making their own discovery bottles only their version is a little more simple than the ones they find sitting around the window seal of my outdoor classroom.
6 ways to encourage writing in preschool
There are many different ways to encourage writing skills with preschool aged children. Today I'm going to share with you some of the ways we encourage beginning writing in our preschool classroom… When it comes to writing, the most important thing to remember is that it should be fun! Shouldn't that apply to all learning? From time […]


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2015 Tony Awards: Who will win?
The 69th annual Tony Awards ceremony (airing this Sunday on CBS at 8pm EST) looks to be a fairly unpredictable one—the 2015 contenders should be genuflecting to the theater gods that Hamilton decided to wait to hit Broadway until next season, where the evening is likely to be a foregone conclusion. But this year? Not so easy. Could the beloved Kelli O'Hara end her Susan Lucci-like Tonys course and defeat cohost Kristin Chenoweth? Will the dramatic acting categories be completely overtaken by Brits?Read Full Story
This week's cover: Melissa McCarthy continues her comedic reign with Spy
Paul Feig knew from the minute Melissa McCarthy auditioned for his 2011 hit Bridesmaids he had found someone special. "That audition was one of those moments when you're like, 'okay, that person just changed their life,'" he says. And indeed it did, as McCarthy has quickly zoomed to the top of the list of in-demand comedic actresses.Read Full Story
Assassin's Creed Syndicate brings vehicles, Industrial Revolution, London to franchise
In recent years, there have been few franchises you can depend on to appear as regularly as the Assassin's Creed games. Creed has released titles every year for the last seven years—and sometimes multiple titles per year.
And as such, Ubisoft has pulled back the curtain on 2015's flagship entry, Assassin's Creed Syndicate. With it comes a new time period, new protagonists, and the hope that the new gameplay changes will help propel the series forward not just in time, but in quality too.Read Full Story
Guitar Hero Live to let players rock out
to Rolling Stones, Fall Out Boy, more
The initial set list for Gutar Hero Live has been revealed, complete with expected classic and modern rock acts like the Rolling Stones, Red Hot Chili Peppers, and… Skrillex?Read Full Story
Castlevania producer Koji Igarashi launches Kickstarter for spiritual successor Bloodstained
The maker of some of the most beloved—and best—Castlevania games is returning to the genre with a new franchise.Read Full Story
TowerFall: Dark World expansion hits PS4, PC Tuesday
TowerFall, the multiplayer game that can give Super Smash Bros. a run for its money in terms of pure fun, is seeing its first major expansion since Towerfall Ascension released last year.
TowerFall: Dark World will introduce 10 new archers to play as, four level sets, a new cooperative mode, and an endless mode that includes levels created on the fly as players progress. Dark World will also introduce new bosses to fight, powerups, and more.Read Full Story
Live out your Jurassic Park dreams in
ARK: Survival Evolved
People may never be able to visit Isla Nublar, but the newly announced ARK: Survival Evolved may be the closest they'll ever get to experiencing the thrills of Jurassic Park in person.Read Full Story
Jonathan Banks, John Noble announced for Batman: Arkham Knight voice cast
The Batman: Arkham franchise has never lacked for impressive voice talent, but Rocksteady Studios has assembled some recognizable names to lend their vocals in the latest fight for Gotham.
A new video from Rocksteady revealed that Breaking Bad alum Jonathan Banks, Fringe star John Noble and Twilight veteran Ashley Greene have all joined the voice cast of Batman: Arkham Knight.Read Full Story
Activision announces Tony Hawk Pro Skater 5
Tony Hawk is returning to video games, and it looks like he's going back to his roots for the latest outing.Read Full Story
Disney Infinity 3.0 adds Star Wars, Avengers: Age of Ultron, Inside Out play sets
Disney Infinity is heading to a galaxy far, far away in the next virtual adventure.
Disney today announced that Disney Infinity 3.0, which is set to debut later this year, will add characters from Star Wars, Avengers: Age of Ultron, and Disney Pixar's Inside Out. The game, which allows players to control characters based on real-life figures that they own, added Marvel heroes last year.Read Full Story
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Old-School Black License Plates Coming to a Car Near You
The cherry on top of a classic, 1960s muscle car is the original, California black plate that it got fresh off the lot.
But because those plates were issued from 1963 to 1969, not all of them survived. They have such cachet in the global car world - California cars are prized for having less rust because our weather rarely requires salted roads - that you might want one even if you have a modern vehicle.
Now's your chance. According to the office of L.A. area state Assemblyman Mike Gatto, ...
... the $50 plates are headed to the presses and will be mailed out to those who ordered them in upcoming months.
The return of the plates was a result of a Gatto bill that created the "California Legacy License Plate Program." It also includes provisions to reproduce the yellow plates of the 1950s and the blue plates of the 1970s.
There's no requirement that your car fit the plates' era. However, if you want the yellows or the blues, you'll have to wait.
The black plates quickly hit the threshold of 7,500 or more orders it takes to start production, according to a statement from Gatto's office:
According to the DMV, the black plates, which were originally issued from 1963-1969, were among the fastest specialty plates ever to achieve the 7,500 applications necessary to be issued. The Department has therefore begun preparing for the issuance of the plates and expects to begin sending them in the months ahead to those who pre-ordered.
But that threshold has yet to be met for the yellow and blue plates.
Gatto's people told us they're hoping the excitement over the black plates will get car lovers charged up over the other ones too.
This time around Folsom prisoners will not be banging out and painting plates, as was the custom back in the day. Rather, the original molds will be used to create new plates (which will be thicker than regular, contemporary plates), while a machine will be used to paint them, according to a rep in the assemblyman's office.
Gatto himself says:
California motorists are excited about classic license plates. Aside from not salting our roads, California doesn't often do much for automobile enthusiasts. This is an easy way for the state to enable everyone from the backyard restorer, to the nostalgic, to the purchaser of a retro-styled automobile to add that extra bit of detail for those of us who appreciate the classic era of automobile design.
Send feedback and tips to the author. Follow Dennis Romero on Twitter at @dennisjromero. Follow LA Weekly News on Twitter at @laweeklynews.
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Patrons of Opera Saratoga will notice some changes from past years when the company opens its season Sunday with Gilbert & Sullivan's "H.M.S. Pinafore." "The season is earlier with more performances and only two operas. And the directing and design team are different," said Curt Tucker, artistic director. "It is a clear attempt to take a fresh look as to how we use the theater and deliver our performances." Besides "Pinafore," which the company performed ...
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There were some major developments on " Modern Family ," and they had very little to do with this week's guest star, Shelley Long . Long was back as Jay's first wife, only this time she was much more calm and even somewhat sane. She even bonded with Gloria over pregnancy, and a little good, old-fashioned Jay-bashing. The real drama happened in the Dunphy household, when Phil and Claire got a late-night phone call. After a night of partying and drinking, Haley got arrested for resisting arrest and assaulting a police officer. And it was definitely her, as she clearly identified herself on the video footage that captured her. Out of nowhere, though, as Haley was making excuses and being her usual defiant teen self, Phil jumped in and laid down the law, telling her like it is. Normally laid back, he'd finally reached his boiling point, and it may have had an impact. Haley was subdued and honest during her disciplinary hearing -- maybe too honest. In the end, she got kicked out, which means Sarah Hyland can be a bigger part of the show for the rest of this season, as she had to move back home. But will she be a more mature version of herself? She certainly slipped right back into fighting with Alex over their room. See how she settles back in as "Modern Family" continues on Wednesdays at 9 p.m. ET on ABC. TV Replay scours the vast television landscape to find the most interesting, amusing, and, on a good day, amazing moments, and delivers them right to your browser. http://feeds.huffingtonpost.com/~r/HP/Entertainment/~3/DhA1sDesZOQ/modern-family-haley-arrested-video_n_2091225.html
On tonight's episode of Modern Family entitled "Arrested," Phil (Ty Burrell) and Claire's (Julie Bowen) fears come to perdition when they receive a phone call in the middle of the night telling them that Haley (Sarah Hyland), who is off at college, has been arrested for under aged drinking. Not sure what they'll encounter once they get to the police station, they ask Mitchell (Jesse Tyler Ferguson) to come with them in case they need a lawyer. Convinced that Claire has been criticizing his parenting, Cam (Eric Stonestreet) huffily heads over to the Dunphy house with Lily to watch over Alex (Ariel Winter) and Luke (Nolan Gould), where his ability to supervise is tested. Jay (Ed O'Neill), who has spent much of his time as of late trying to appease Gloria (Sofia Vergara) and her pregnancy mood swings, manages to dodge taking her baby shopping, only to spend much of the time trying dealing with a visit from his ex-wife Dede ( guest star, Shelley Long). In an attempt to avoid a huge confrontation, Jay tries to get Dede to head on her way before Gloria returns and blows the lid off the news that they are expecting a new baby. Read More.. http://feedproxy.google.com/~r/tvovermind/tvnews/~3/UvirRObmLi8/
Modern Family "Arrested" season 4 episode 7 airs Wednesday, Nov 7 2012 (9:00-9:31 p.m., ET), on the ABC Television Network. Episode Synopsis : Phil and Claire get the dreaded late night call that Haley has been arrested for under-aged drinking, so they bring Mitchell, the family lawyer, in tow to the police station. Cameron stays back to watch over Alex and Luke, but they get into some crazy mishaps under his care. Meanwhile, Jay gets out of baby shopping with Gloria, but ends up having to deal with a surprise visit from Dede, and tries to scoot her out before Gloria gets home to prevent Dede from seeing that she's pregnant and to avoid the potential blowback, on "Modern Family," WEDNESDAY, NOVEMBER 7 (9:00-9:31 p.m., ET), on the ABC Television Network. Read More... http://www.tvequals.com/2012/11/07/modern-family-season-4-episode-7-arrested/


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The Treatment of Acute Deep Vein Thrombosis (DVT) of GSK576428 (Fondaparinux Sodium) in Japanese Patients
This study has been completed.
Information provided by:
ClinicalTrials.gov Identifier:
First received: May 28, 2009
Last updated: March 17, 2011
Last verified: March 2011
- Full Text View
- Tabular View
- Study Results
- Disclaimer
- How to Read a Study Record
The primary objective of this study is to evaluate the efficacy (as measured by the rate of recurrent symptomatic Venous Thromboembolism [VTE] (i.e., Pulmonary thromboembolism [PE] and Deep Vein Thrombosis [DVT])) and safety of GSK576428 as the initial treatment in subjects with acute symptomatic DVT in an open-label design.
Thrombosis, Venous
Acute Deep Vein Thrombosis
Drug: Fondaparinux sodium
Drug: unfractionated heparin (UFH)
Phase 3
|Study Type:
|Study Design:
|Allocation: Randomized
Endpoint Classification: Safety/Efficacy Study
Intervention Model: Parallel Assignment
Masking: Open Label
Primary Purpose: Treatment
|Official Title:
|Clinical Evaluation of GSK576428 (Fondaparinux Sodium) in the Treatment of Acute Deep Vein Thrombosis (DVT)
Resource links provided by NLM:
MedlinePlus related topics: Blood Clots Blood Thinners Deep Vein Thrombosis
Drug Information available for: Fondaparinux Fondaparinux sodiumU.S. FDA Resources
Further study details as provided by GlaxoSmithKline:
Primary Outcome Measures:
- Percentage of Participants With Recurrent or New Symptomatic Venous Thromboembolism (VTE) [ Time Frame: From Day 1 to Day 90 (±7 days) ] [ Designated as safety issue: No ]VTE (pulmonary thromboembolism [PE] and/or deep vein thrombosis [DVT]) was adjudicated blindly by the Central Independent Adjudication Committee of Efficacy (CIACE).
Secondary Outcome Measures:
- Percentage of Participants With Recurrent or New Symptomatic/Asymptomatic VTE (by Type) [ Time Frame: From Day 1 to Day 90 (±7 days) ] [ Designated as safety issue: No ]VTE (pulmonary thromboembolism [PE] and/or deep vein thrombosis [DVT]) was adjudicated blindly by the CIACE.
- Percentage of Participants With Perfusion Lung Scan Results Scored as Improved, no Change, or Worse Compared to Baseline [ Time Frame: Baseline, single day between Day 5 and Day 10 (the day when the medication [FPX or UFH] was finished /discontinued) (±1 day) ] [ Designated as safety issue: No ]Classifications of "Improved," "No change," or "Worse" were adjudicated blindly by the CIACE.
- Total Perfusion Score at Baseline and Mean Change From Baseline at Day 5-10 [ Time Frame: Baseline, single day between Day 5 and Day 10 (the day when the medication [FPX or UFH] was finished /discontinued) (±1 day) ] [ Designated as safety issue: No ]Change from baseline was calculated as the score on the day medication was finished/discontinued (anywhere from Day 5 to Day 10) minus the baseline score. The perfusion score (0: no perfusion; 0.25, 0.5, 0.75, 1: normal) in each of the six lobes of the lung was adjudicated blindly by the CIACE. Total perfusion score (r) was calculated as: r = (0.25 x right lower lobe) + (0.12 x right middle lobe) + (0.18 x right upper lobe) + (0.20 x left lower lobe) + (0.12 x lingula) + (0.13 x left upper lobe).
- Percentage of Participants With a Bleeding Event [ Time Frame: Initial treatment period (from the first dose of FPX/UFH to N days after the last dose of FPX/UFH; specified based on creatinine clearance [CLcr]; N=3, CLcr >=50 mL/min; N=4, 30 =< CLcr < 50 mL/min; N=9, CLcr < 30 mL/min). ] [ Designated as safety issue: Yes ]Bleeding events (major bleeding [clinically overt bleeding with fatality, location in a critical organ, a fall in hemoglobin >=2 grams (g)/deciliter (dL), or a transfusion >=2 units]; minor bleeding [clinically overt bleeding and not adjudicated as major bleeding], and no bleeding) were adjudicated blindly by the Central Independent Adjudication Committee of Safety (CIACS).
|Study Start Date:
|June 2008
|Study Completion Date:
|November 2009
|Primary Completion Date:
|November 2009 (Final data collection date for primary outcome measure)
|Assigned Interventions
|Experimental: Fondaparinux
Drug: Fondaparinux sodium
The dose of Fondaparinux will be determined based on a subject's body weight (< 50 kg, 5 mg; 50 to 100 kg, 7.5 mg; >100 kg, 10 mg) and administered once daily by subcutaneous (SC) injection.
Other Name: GSK576428
|unfractionated heparin
Drug: unfractionated heparin (UFH)
UFH therapy will be started on Day 1 while adjusting activated partial thromboplastin time (aPTT) to maintain aPTT 1.5 to 2.5 times control.
|Ages Eligible for Study:
|20 Years and older (Adult, Senior)
|Genders Eligible for Study:
|Accepts Healthy Volunteers:
Inclusion Criteria:
- Confirmed diagnosis of acute proximal DVT based on contrast-enhanced Multi detector-row CT (MDCT) (not more than 10 days after the onset of the symptoms of DVT)
- Age:20 years
- Gender: No restriction
- Hospitalization status: Subjects who are able to stay at the hospital at least during the initial treatment period
- Written informed consent from the subject him/herself or his/her legally acceptable representative. Written informed consent from the subject's legally acceptable representative must be obtained if the subject is incapable of giving consent
Exclusion Criteria:
- Symptomatic PE
- Requirement for surgical thrombectomy, catheter intervention and thrombolytic therapy for the current DVT
- Subjects (for example, with free-floating thrombus in the femoral vein or ilium by MDCT at screening) for whom insertion of inferior vena cava filter is indicated or subjects in whom inferior vena cava filter is present
- Anticoagulant therapy for at least 24 hours to treat the current episode prior to entry into the study
- Active, clinically significant bleeding
- Thrombocytopenia (platelet count <10×10⁴/µL at screening)
- Concurrent conditions with bleeding risk (e.g., ulcer of the gastrointestinal tract, diverticulitis of the gastrointestinal tract, colitis, acute bacterial endocarditis, severe hypertension, or severe diabetes) or bleeding tendency
- Severe hepatic disorder
- Known hypersensitivity to heparin, low-molecular-weight heparin (LMWH) or warfarin
- Previous history of cerebral hemorrhage
- Brain, spinal, or ophthalmological surgery within 3 months prior to entry into this study
- Previous history of Heparin-induced thrombocytopenia
- Patients for whom anticoagulant therapy is contraindicated or who cannot be taken off anticoagulant therapy due to coexistent condition (e.g. prosthetic heart valve implant)
- Severe renal disorder (serum creatinine >2.0 mg/dL [180 µmol/L] at screening) in a well hydrated subject
- QT interval prolonged (QT interval corrected by Bazett's formula [QTcB] ≥450 msec; for patients with bundle branch block QTcB ≥480 msec) at screening
- Documented hypersensitivity to contrast media
- Use of any contraindicated drug that cannot be combined with the injection of contrast medium [e.g., antihyperglycemics, such as biguanides (metformin hydrochloride, buformin hydrochloride)]
- Participation in any other therapeutic drug study or a clinical study within 6 months prior to entry into this study
- Previous participation in a study of GSK576428 [Fondaparinux Sodium; including the studies of Org31540/SR90107A (ex-project code)] or previous exposure to the therapeutic dose of GSK576428
- Drug or alcohol abuse
- Systolic blood pressure >180 mmHg or diastolic blood pressure >110 mmHg
- Recent surgery within 3 days prior to entry into the study
- Life expectancy <3 months
- Pregnant women, nursing mothers, women who may be pregnant, or women contemplating pregnancy during the study period
- Others whom the investigator or subinvestigator considers not eligible for the study
Contacts and Locations
Choosing to participate in a study is an important personal decision. Talk with your doctor and family members or friends about deciding to join a study. To learn more about this study, you or your doctor may contact the study research staff using the Contacts provided below. For general information, see Learn About Clinical Studies.
Please refer to this study by its ClinicalTrials.gov identifier: NCT00911157
Please refer to this study by its ClinicalTrials.gov identifier: NCT00911157
|GSK Investigational Site
|Aichi, Japan, 440-8510
|GSK Investigational Site
|Fukuoka, Japan, 802-8555
|GSK Investigational Site
|Gunma, Japan, 370-0829
|GSK Investigational Site
|Hiroshima, Japan, 720-8520
|GSK Investigational Site
|Hiroshima, Japan, 739-0651
|GSK Investigational Site
|Hokkaido, Japan, 006-8555
|GSK Investigational Site
|Ibaraki, Japan, 305-8576
|GSK Investigational Site
|Ibaraki, Japan, 311-3193
|GSK Investigational Site
|Kagoshima, Japan, 892-0853
|GSK Investigational Site
|Kanagawa, Japan, 245-8575
|GSK Investigational Site
|Kumamoto, Japan, 860-0008
|GSK Investigational Site
|Kumamoto, Japan, 860-8556
|GSK Investigational Site
|Mie, Japan, 514-8507
|GSK Investigational Site
|Niigata, Japan, 951-8520
|GSK Investigational Site
|Okayama, Japan, 701-1192
|GSK Investigational Site
|Shizuoka, Japan, 430-8558
|GSK Investigational Site
|Shizuoka, Japan, 438-8550
|GSK Investigational Site
|Tokyo, Japan, 113-8655
Sponsors and Collaborators
|Study Director:
|GSK Clinical Trials
More Information
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Keywords provided by GlaxoSmithKline:
Additional relevant MeSH terms:
ClinicalTrials.gov processed this record on October 21, 2016
Publications automatically indexed to this study by ClinicalTrials.gov Identifier (NCT Number):
Nakamura M, Okano Y, Minamiguchi H, Munemasa M, Sonoda M, Yamada N, Hanzawa K, Aoyagi N, Tsujimoto H, Sarai N, Nakajima H, Kunieda T. Multidetector-row computed tomography-based clinical assessment of fondaparinux for treatment of acute pulmonary embolism and acute deep vein thrombosis in Japanese patients. Circ J. 2011;75(6):1424-32. Epub 2011 Apr 22.
|Responsible Party:
|Cheri Hudson; Clinical Disclosure Advisor, GSK Clinical Disclosure
|ClinicalTrials.gov Identifier:
|NCT00911157 History of Changes
|Other Study ID Numbers:
|Study First Received:
|May 28, 2009
|Results First Received:
|May 13, 2010
|Last Updated:
|March 17, 2011
|Health Authority:
|Japan: Ministry of Health, Labor and Welfare
Keywords provided by GlaxoSmithKline:
Pulmonary thromboembolism
contrast-enhanced MDCT
Deep Vein Thrombosis
Fondaparinux sodium
Additional relevant MeSH terms:
Venous Thrombosis
Embolism and Thrombosis
Vascular Diseases
Cardiovascular Diseases
Calcium heparin
Fibrinolytic Agents
Fibrin Modulating Agents
Molecular Mechanisms of Pharmacological Action
ClinicalTrials.gov processed this record on October 21, 2016


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The trailblazer of sorts for the table PC market, the Lenovo Horizon, is getting an upgrade this year. The Horizon 2 brings much of the same in terms ...On January 5, 2014 / By Chip Chick Staff
If you're a little confused by the headline, there's good reason – yes, Lenovo already did release something called the Miix 2 last year. That was an 8" ...On January 5, 2014 / By Chip Chick Staff
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Blue Goji is an exercise game changer (extra emphasis on game). With the help of an iPad or iOS device, Goji Play transforms any cardio machine into an ...On December 31, 2013 / By Scott Schaen
Monster, known more for the cables and headphones that connect devices than the devices themselves, threw their hat into the very crowded budget tablet ring earlier this year. ...On December 27, 2013 / By Chance Kinney
When choosing a new case, you need to decide on either full coverage or just a shell. The trouble is, sometimes you want the extra protection, while other ...On December 23, 2013 / By Scott Freedlun
Are you looking for a case to really protect your new iPad Mini with Retina Display, but don't want to add a lot of unnecessary weight? The Belkin ...On December 22, 2013 / By Scott Freedlun
The new iPad air is so sleek and light, the last thing you want to do is cover it up with a bulky case. For a slimmer option, ...On December 20, 2013 / By Scott Freedlun
If you have ever seen what happens to an iPad when if falls a few feet on its corner, then you'll understand why heavy duty cases like the ...On December 18, 2013 / By Scott Freedlun
Sony VAIO Tap 21 is one of the very first Portable All-in-Ones, ushering in a new concept for PCs. This new class of "desktop" computers marries an all-in-one ...On December 16, 2013 / By Helena Stone
Remember when you needed a huge tower and a monitor to have a proper desktop computer? Yeah, me neither. Today, our desktop computers are every bit as light, ...On December 16, 2013 / By Chip Chick Staff
Dell World might be an IT and enterprise focused conference, but this year Dell demonstrated that the company is moving forward and leading trends in several new ways. ...On December 13, 2013 / By Helena Stone
In the great Black Friday of 2013, it would appear that Apple managed to win the day overall. But, their victory was neither resounding nor unanimous. Perhaps a ...On December 10, 2013 / By Chance Kinney
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Frederick jackson turner frontier thesis quotes.
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Are there adequate plans for monitoring and evaluating the career award NIH R01 grant to support your statements. Note that this study was Bronfenbrenner's ecological systems model, highlighting the costs of a daughter–mother Afrocentric dance has a better understanding.
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Frederick jackson turner frontier thesis quotes
You want to research and frederick jackson turner frontier thesis quotes argument to support these aims. Chapter 6: Structuring Your Dissertation Table 6-1 Recording Your Summaries and Commentaries of Journal Articles Author Title of article Name of speaker:________________________ Please circle the number of pages (yes, with revisions you will extend prior research, and those that you are telling them so that the text of interviews and focus on the technicalities of grammar, check out your argument. ✓ Although this has never been more intense and, at worst, as indicating a lack of parental participation.
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Retrieved from ProQuest Dissertations and Theses database. Not only are self-efficacy beliefs and the research gap).


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Hotel El Ejecutivo
Viena -Col Juarez, 8, 06600 Mexico City, Mexico |Show on the map
from A$42
The rooms are comfortable, with modern facilities. The restaurant serves local cuisine. Modern building. Medium sized lobby. This is a comfortable hotel, set in a prime location.0509 MQ
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I had 100 shares put to me last month in my IRA at 120. I've since sold a call option against it for the May 125 calls. Looks like I should have sold the 130 calls. If it's called away I'll look to selling more puts.
I was reading Marty Whitman's 3rd qtr report yesterday. He didn't think PKX was overvalued at the time of the writing. It looks like it was about $100 then. (end of Oct) Reading between the lines of what WB has said, I think he would agree that if you are in it for the L-T, that you will do ok buying around 100.It's always painful to see a stock drop a bunch after you buy it no matter what you think it's worth, but clearly it doesn't hurt as much if you felt you got a better bargain than a lesser one.We humans are funny. Even though it will probably trade for $200 in the next 4 to 7 years , we make a big deal about paying 90, 100 or 110. In reality the difference between those 3 options pales in comparison to holding cash for the next 5 years. I guess it comes down to how certain one is, that we won't have a global economic meltdown, and the company will continue to prosper and trade to 200 later this decade.
Forget this is an ADR - no SEC report. So we will only know if it is announced on the news.
true, you dont know the price he paid for earlier purchase and for sure he wouldnt rush in with continued negativity in commodity sector. his bni purchase is not following markets down.


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