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Sephora Blonde Ambition Contour Eye Pencil ($9.00 for 0.04 oz.) is described as "beige." It's a pale, gilded beige with a pearly sheen. It had good color payoff in a single pass, but it's only semi-opaque and buildable to about semi-opaque, even though I tried to layer it. It's sufficient for brightening the eye, and it can be evened out with a brush to blend the eyeliner together. NARS Rue Bonaparte is matte. MAC Gilded White is very similar, perhaps a touch whiter. Other champagne eyeliners are warmer, more beige. See comparison swatches.Read Full Review
Physicians Formula Warm Happy Booster Glow & Mood Boosting Blush
Physicians Formula Warm Happy Booster Glow & Mood Boosting Blush ($11.99 for 0.24 oz.) is a warm, light-medium coral-pink with a soft, sparkling sheen. MAC Simmer is more intense, darker. Edwared Bess Secret Affair is more orange. theBalm Frat Boy is pinker, less shimmery. NARS Deep Throat is a bit darker. MAC Supercontinental is warmer, less pink. MAC Legendary is lighter. MAC Flaming Chic is less shimmery. Chanel Fleur de Lotus is a bit warmer, brighter.
See comparison swatches.
Revlon Super Lustrous Lipstick (Berry Couture, Fuchsia Shock, Lover's Coral)
Revlon Berry Couture Super Lustrous Lipstick ($7.99 for 0.13 oz.) is a cool-toned, fuchsia-berry with a soft shine. The color was buildable from sheer to semi-opaque–it looked a bit like a lip stain, because of how thin the formula is, as it looks a lot like my natural lip; not heavy-looking at all. This particular shade wore for three and a half hours on me, which is shy of average, but for something with as much slip as this does going on, it was good wear. Revlon Sorbet is warmer. MAC Lickable is slightly brighter. Dior Lucky is warmer. See comparison swatches.Read Full Review
MAC Coppertone Blush
MAC Coppertone Blush ($21.00 for 0.21 oz.) is described as a "peach brown [with a matte finish]." It's a medium, muted orange with brown undertones and a matte finish. I get the "peach brown" description, though. NARS Gina is a touch lighter. MAC Seasonal Appeal is less warm. MAC Eternal Sun is a bit darker. MAC Barefaced is more shimmery. Chanel Espiegle is more shimmery, lighter. See comparison swatches.Read Full Review
Hare Polish Bisbee 2.0, Leap Light Year, Star Tropics Nail Lacquers
Hare Polish Bisbee 2.0 Nail Lacquer ($10.00 for 0.50 fl. oz.) is described as a "turquoise jelly, accented with bright yellow-golden hexes and squares … plus gold shimmer." It's a cool-toned, aqua blue turquoise with square and hexagon-shaped gold shimmer (that turns almost green when it gets covered with the base color) and a fine dusting of gold shimmer. I applied two coats of polish, as the brand advised, and it was semi-opaque and had that signature squishy, slightly translucent jelly look. I couldn't think of any dupes (not even just a turquoise jelly!).Read Full Review
Chanel Delicatesse Ombres Fleuries Eyeshadow Palette
Chanel Delicatesse Ombres Fleuries Eyeshadow Palette ($60.00 for 0.14 oz.) has finishes that "range from matte to satin to shimmer," with a "smudge-proof formula [that] can be applied dry for subtle shading, or dampened for more intense colour, all with long-wearing results." Overall, it's a good palette with an interesting mix of colors and textures. When trying it out, the green shade wasn't as smooth or as easy to use as the other three shades, as it had an almost sparkly finish that made it less inclined to smooth out and bind together. I didn't encounter this issue with the other shades, though, and they applied more smoothly and were easier to blend. I wore all four shades together, and the green one was very slightly creased after eight hours, while the rest held up without creasing and had only minor fading after nine hours of wear.Read Full Review


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Myocardial Infarction First Aid
A selection of articles related to myocardial infarction first aid.
Original articles from our library related to the Myocardial Infarction First Aid. See Table of Contents for further available material (downloadable resources) on Myocardial Infarction First Aid.
- King James Bible: Numbers, Chapter 7
- Chapter 7 7:1 And it came to pass on the day that Moses had fully set up the tabernacle, and had anointed it, and sanctified it, and all the instruments thereof, both the altar and all the vessels thereof, and had anointed them, and sanctified them; 7:2 That...
Old Testament >> Numbers
- Hulse, David Allen
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Real Interviews >> Authors
- Hulse, David Allen
- >From an early age, David Allen Hulse has made a diligent study of the alphabets of the ancient world. Even as a child, David possessed a great affinity for the alphabets of Egypt, Phoenicia, and Greece. In college, a reading of MacGregor Mathers' Kabbalah...
Real Interviews >> Authors
- Morrison, Dorothy
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Mystic Sciences >> Alchemy
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Paganism & Wicca >> Holidays
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- DURECT's (DRRX) CEO Jim Brown on Q4 2015 Results - Earnings Call Transcript
- Greetings. And welcome to the Fourth Quarter 2015 DURECT Earnings Conference Call. At this time, all participants are in a listen-only mode.
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Myocardial Infarction First Aid Topics
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Milwaukee Rep adds Janis Joplin show to lineup
The Milwaukee Repertory Theater has added a new production, featuring the music of Janis Joplin, to the end of its current season.
"One Night With Janis Joplin," starring Mary Bridget Davies, will run May 3 through June 2 in the Quadracci Powerhouse Theater, 108 E. Wells St. »Read Full Article(1)
No word yet on fate of Michelle Shocked show at Madison bar
Michelle Shocked's May 4 show in Madison - the last remaining gig on her tour, after anti-gay comments at a concert over the weekend led the rest of the venues to cancel the alt-folk singer's shows - is still on, at least for now.
The Capitol Times in Madison reports that the Harmony Bar in Madison is waiting to make a final decision on the show until the bar's owner, Keith Daniels, returns from an out-of-town vacation late next week. »Read Full Article
Phillip Phillips answers 10 for Tap


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The U.S. territory is debating whether to fumigate with the insecticide Naled.
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Vincent Mallet, MD, PhD; Elisabeth Nicand, MD; Philippe Sultanik, MD; Catherine Chakvetadze, MD; Sophie Tessé, PhD; Eric Thervet, MD, PhD; Luc Mouthon, MD, PhD; Philippe Sogni, MD, PhD; Stanislas Pol, MD, PhD
Note: Drs. Mallet, Sogni, and Pol contributed equally to this article.
Acknowledgment: The authors acknowledge the patients' readiness to help others by accepting their case be the focus of this article. The authors also thank Anaïs Vallet-Pichard, MD; Hélène Fontaine, MD; Matthew Albert, MD, PhD; and Marie Françoise Avril, MD, PhD, for their help in the care of the reported patients and for their advice on the manuscript.
Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M10-0831.
Reproducible Research Statement:Study protocol and statistical code: Not available. Data set: Available from Dr. Mallet (e-mail, firstname.lastname@example.com) after establishing written agreement with the authors.
Requests for Single Reprints: Vincent Mallet, MD, PhD, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Cochin Saint-Vincent de Paul, Unité d'Hépatologie, 27 rue du Faubourg Saint Jacques, 75014 Paris, France; e-mail, email@example.com.
Current Author Addresses: Drs. Mallet, Sultanik, Chakvetadze, Sogni, and Pol: Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Cochin Saint-Vincent de Paul, Unité d'Hépatologie, 27 rue du Faubourg Saint Jacques, 75014 Paris, France.
Drs. Nicand and Tessé: Hôpital d'Instruction des Armées du Val-de-Grâce, Centre National de Référence des hépatites à transmission entérique (hépatite E), 74 boulevard de Port-Royal, 75230 Paris, France.
Dr. Thervet: Assistance Publique-Hôpitaux de Paris, Hôpital Necker Enfants Malades, Unité de Transplantation rénale, 149 rue de Sévres, 75015 Paris, France.
Dr. Mouthon: Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Cochin Saint-Vincent de Paul, Service de Médecine Interne, 27 rue du Faubourg Saint Jacques, 75014 Paris, France.
Author Contributions: Conception and design: V. Mallet, S. Pol.
Analysis and interpretation of the data: V. Mallet, E. Nicand, S. Tessé, L. Mouthon, P. Sogni, S. Pol.
Drafting of the article: V. Mallet, E. Nicand, E. Thervet, P. Sogni.
Critical revision of the article for important intellectual content: V. Mallet, E. Thervet, P. Sogni, S. Pol.
Final approval of the article: V. Mallet, C. Chakvetadze, E. Thervet, L. Mouthon, P. Sogni, S. Pol.
Provision of study materials or patients: V. Mallet, E. Nicand, P. Sultanik, C. Chakvetadze, E. Thervet, L. Mouthon, P. Sogni.
Administrative, technical, or logistic support: V. Mallet, P. Sultanik, S. Tessé, S. Pol.
Collection and assembly of data: V. Mallet, C. Chakvetadze, E. Thervet.
Mallet V., Nicand E., Sultanik P., Chakvetadze C., Tessé S., Thervet E., Mouthon L., Sogni P., Pol S.; Brief Communication: Case Reports of Ribavirin Treatment for Chronic Hepatitis E. Ann Intern Med. 2010;153:85-89. doi: 10.7326/0003-4819-153-2-201007200-00257
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© 2016
Published: Ann Intern Med. 2010;153(2):85-89.
There is currently no accepted treatment of chronic hepatitis E virus (HEV) infection.
To report 2 patients in whom ribavirin therapy seemed to alter the natural history of chronic HEV infection.
Case reports.
Hepatology unit of a tertiary care center in France.
A kidney and pancreas transplant recipient and a patient with idiopathic CD4+ T lymphocytopenia, both with biopsy-proven chronic HEV infection.
Patients received oral ribavirin, 12 mg/kg of body weight daily for 12 weeks.
Liver function tests, detection of HEV RNA (viremia and stool shedding) by reverse transcriptase polymerase chain reaction, and anti-HEV IgM and IgG antibodies.
Both patients had normalized liver function test results after 2 weeks of treatment and cleared HEV after 4 weeks of treatment. Hepatitis E virus RNA remained undetectable in the serum and stools throughout follow-up (3 months and 2 months for the first and second patient, respectively). Side effects were considered mild.
Given the relatively short follow-up, the achievement of HEV eradication could not be claimed.
Ribavirin is a potentially effective treatment of HEV infection and should be evaluated in patients with chronic HEV infection.
Chronic hepatitis E virus (HEV) infection is an emerging infectious disease in immunocompromised patients. Therapy has been limited to supportive measures.
In 2 patients with chronic HEV infection who received treatment with ribavirin, liver enzyme levels normalized and the virus was no longer detected in blood and stool. These results persisted after treatment was stopped.
Longer follow-up of these 2 patients is needed. Controlled trials of ribavirin treatment in patients with chronic HEV infection are needed to determine efficacy. In addition, ribavirin is contraindicated in pregnancy (U.S. Food and Drug Administration category X drug).
Antiviral therapy of chronic HEV infection may be possible.
—The Editors
Hepatitis E virus (HEV) is highly endemic in developing countries and is an emerging autochthonous (locally acquired) disease in industrialized countries in which a preferential zoonotic method of transmission is reported (1). Acute HEV infection has a high mortality rate in older persons, pregnant women, and patients with underlying chronic liver disease (2–5). Acute HEV infection can also evolve into chronic infection in immunocompromised patients (6, 7). The reported rate of chronicity after HEV infection is approximately 60% in solid-organ transplant recipients with persistent viral shedding observed in blood, stool, and liver biopsy samples for up to 7 years (8–10).
The diagnosis of HEV infection is based on the detection of HEV RNA in blood, stool, or liver biopsy samples and specific anti-HEV IgM and IgG antibodies. In some patients, including nonimmunocompromised patients, the course, maturation, and duration of anti-HEV IgG and IgM antibodies may be altered, and silent serologic acute or chronic hepatitis E cases have been reported (7, 9).
Chronic HEV infection can lead to cirrhosis and end-stage liver disease; in transplant recipients, it can lead to loss of liver graft (8, 11, 12). The prevalence of chronic HEV infection in transplant recipients is estimated from 0.4% in low endemic areas to 1.9% in areas with a higher prevalence (8, 12, 13). The incidence of chronic HEV infection in immunocompromised patients is difficult to estimate because of a lack of systematic HEV screening in this population. Nevertheless, the French National Reference Laboratory has reported an increasing number of cases of chronic HEV infection in immunocompromised patients in France (14).
Currently, no accepted treatment of chronic HEV infection exists, although cases of HEV clearance have been reported in transplant recipients once their immunosuppressive medication was tapered or when interferon-α was administered. Both approaches, however, introduce the risk for graft rejection (10, 15, 16). Regarding management of acute HEV infection, clinical intervention is limited to supportive care.
Ribavirin [1-(β-d-ribofuranosyl)-1,2,4-triazole-3-carboxamide) is a guanosine analogue that has broad-spectrum activity against DNA and RNA viruses, including activity against Orthomyxoviridae, Herpesviridae, respiratory syncytial viruses, Flaviviridae, and agents of many viral hemorrhagic fevers (17). Ribavirin (combined with interferon) has been used since the early 1990s to treat chronic hepatitis C infection and has been used as monotherapy in transplant recipients with chronic hepatitis C virus infection (18–21). We report the efficacy of ribavirin in 2 immunocompromised patients with chronic HEV infection.
The first patient was a diabetic white man aged 40 years who, after 2 years of hemodialysis, received a first simultaneous kidney and pancreas transplant from a deceased donor in November 1998. The immunosuppressive regimen included an initial 10-day course of antithymoglobulins; corticosteroids, 500 mg/d at day 0 followed by rapid tapering to reach 10 mg/d; tacrolimus dosed to achieve a targeted trough concentration between 10 and 15 ng/mL; and mycophenolate mofetil, 1000 mg/d, adapted to clinical outcome. The patient did not have any signs of acute rejection and was free of insulin when discharged, with a serum creatinine level of 90 µmol/L (1 mg/dL).
In January 2006, the patient presented to our unit for unexplained hepatitis lasting longer than the previous 38 months. Physical examination was normal. Serum alanine aminotransferase (ALT) level was 1.6 times the upper limit of the normal range. Aspartate aminotransferase (AST), γ-glutamyltransferase (GGT), and alkaline phosphatase levels were normal. Total bilirubin level was 19 µmol/L (1.1 mg/dL), with predominance of unconjugated bilirubin. Serum creatinine level was 144 µmol/L (1.6 mg/dL). Prothrombin time was normal. The patient tested positive for anti–hepatitis C virus antibodies and negative for anti–hepatitis B virus IgG core antibodies. Genome amplifications of hepatitis B virus, hepatitis C virus, cytomegalovirus, herpes simplex virus, and Epstein–Barr virus were all negative. Ferritin and transferrin saturation blood levels were normal; antiliver and antinuclear antibodies were negative; and serum α1-antitrypsin, copper, and ceruloplasmin levels were normal—which ruled out hemochromatosis, autoimmune hepatitis, and α1-antitrypsin deficiency and Wilson disease, respectively. Liver ultrasonography findings were normal. Hepatitis C virus genome remained undetectable over time (limit of detection, 12 IU/mL).
Hepatitis E virus infection was diagnosed in September 2008 on the basis of amplification of HEV RNA (genotype 3f; GenBank accession number GU936617) and detection of anti-HEV IgG and anti-HEV IgM antibodies (EIAgen HEV IgG and EIAgen HEV IgM, Adaltis, Bologna, Italy) in the serum (Figure 1). In our study, HEV RNA was amplified with primers targeting the HEV open reading frame 2 region. Two reverse transcriptase polymerase chain reaction (RT-PCR) methods were used: real-time polymerase chain reaction that was sensitive for all HEV genotypes and conventional RT-PCR, followed by sequence analysis of the 330-nucleotide open reading frame 2 product. The detection limit of RT-PCR was 100 copies of equivalent genome per milliliter of serum by using serial 10-fold dilutions of plasmid DNA (pGEM-HEV) as a standard curve (22). Amplification of glyceraldehyde 3-phosphate dehydrogenase was used as an internal control to rule out RT-PCR inhibitors. An IgG avidity index at 97% suggested past contact with the virus. Serum and plasma samples collected at the time of the transplantation in 1998 and stored until 2008 at −80 °C were screened retrospectively, and possible exposure to the virus was dated to 2003 based on the detection of both anti-HEV IgM and IgG antibodies; however, HEV RNA could not be amplified in both techniques. In 2007, HEV RNA was detected, showing a 99.5% identity with the genome sequence amplified in 2008. A 30-mm liver biopsy (spanning 10 portal tracts) was done in April 2009 and showed evidence of chronic hepatitis with moderate activity and extensive fibrosis (METAVIR activity [A] and fibrosis [F] scores of A2 and F3). The liver biopsy showed no steatosis, steatohepatitis, or vascular abnormality. The CD4+ T-lymphocyte count was 0.72 × 109 cells/L at that time. The CD8+ T-lymphocyte count was 0.58 × 109 cells/L. The patient had never traveled to endemic areas but did report frequent consumption of undercooked pork, suggesting an autochthonous zoonotic transmission method of HEV.
The graph plots the number of times the ALT level was above the ULN, by date. Genome amplifications of hepatitis B virus and hepatitis C virus were both negative. Other causes of chronic liver disease, including hemochromatosis, autoimmune hepatitis, α1-antitrypsin deficiency, and Wilson disease, were also ruled out. For the serologic and RT-PCR tests, a plus symbol indicates a positive result and a minus symbol indicates a negative result. ALT = alanine aminotransferase; ELISA = enzyme-linked immunosorbent assay; HEV = hepatitis E virus; RT-PCR = reverse transcriptase polymerase chain reaction; ULN = upper limit of normal.
In September 2009 (82 months after the presumed date of initial infection), ribavirin treatment, 400 mg twice daily (total daily dose, 12.3 mg/kg of body weight), was initiated with the informed consent of the patient. The immunosuppressive regimen was not modified. Two weeks later, ALT, AST, and GGT levels returned to within-normal limits. Four weeks after the initiation of ribavirin treatment, HEV RNA was undetectable (under the limit of detection of the assay) in the serum, and HEV IgM antibodies were negative. No fecal specimen was available for HEV RNA detection at that time. All of these findings were confirmed at weeks 6, 8, 10, and 12 of treatment. Ribavirin dose was progressively decreased to 200 mg/d because of mild anemia (nadir hemoglobin level, 92 g/L), and treatment was stopped after 12 weeks. Three months after cessation of treatment, liver function test results remained normal and HEV RNA was undetected in serum and stool.
The second patient was a white woman aged 57 years with idiopathic CD4+ T lymphocytopenia and a primary deficiency in IgG-1, -2, and -4 subclasses. Her medical history included recurrent upper respiratory tract infections since childhood, with secondary bronchiectasia and moderate chronic respiratory insufficiency, and chronic cutaneous and genital human papillomavirus infection that evolved to chronic epidermodysplasia verruciformis (since age 7 years), Bowen disease (age 47 years), spinocellular cancer (age 47 years), and intraepithelial neoplasia of the vulva (age 48 years). She also reported primary cancer of the breast (age 37 years), appendicular abscess (age 52 years), and several episodes of urolithiasis.
She was first seen in our unit in July 2009 for abnormal liver function test results and a 10-kg weight loss over the previous 6 months. Apart from the dermatologic lesions, the physical examination was normal. Levels of ALT, AST, GGT, and alkaline phosphatase were 8, 5, 7.5, and 1 times the upper limit of the normal range, respectively. Total bilirubin level was 14 µmol/L (0.8 mg/dL). The CD4+ T-lymphocyte count was 0.22 × 109 cells/L. The CD8+ T-lymphocyte count was 0.05 × 109 cells/L. The CD19+ B-lymphocyte count was 0.03 × 109 cells/L. The serum creatinine level was 63 µmol/L (0.7 mg/dL). Prothrombin time index was 97%. The patient tested negative for anti–hepatitis A virus IgM antibodies, anti–hepatitis C virus antibodies, anti–hepatitis B virus IgG core antibodies, and anti–HEV antibodies (HEV IgG enzyme-linked immunosorbent assay, Abbott Laboratories, Park, Illinois). Genome amplifications of hepatitis B virus, hepatitis C virus, cytomegalovirus, herpes simplex virus, and Epstein–Barr virus were negative. Ferritin blood level was normal; antiliver and antinuclear antibodies were negative; and serum α1-antitrypsin, copper, and ceruloplasmin levels were normal. Liver ultrasonography findings were normal.
In December 2009, a 9-mm liver biopsy (spanning 10 portal tracts) showed evidence of chronic hepatitis, with moderate activity and mild fibrosis (METAVIR scores of A2 and F1). At that time, HEV RNA was amplified (genotype 3c; GenBank accession number HM066937) from both serum and stool samples (Figure 2), and a low anti-HEV IgM reactivity (EIAgen HEV IgM) was detected in the absence of a detectable anti-HEV IgG antibody (EIAgen HEV IgG). Two previous serum samples collected in April and July 2009 (stored at −80 °C) were positive for HEV RNA and anti-HEV IgM antibody, confirming chronic HEV infection. The patient reported having traveled to the south of France in November 2008 where she consumed pig liver sausage, suggesting autochthonous zoonotic transmission. Two weeks later (12 months after the presumed date of infection), ribavirin treatment, 600 mg/d divided into 2 doses (total daily dose, 12 mg/kg), was initiated with the informed consent of the patient. Two weeks later, ALT and AST levels returned to normal limits. After 4 weeks of treatment, HEV RNA was undetectable in the serum and stools. Ribavirin treatment was stopped after 12 weeks. Two months after the end of treatment, liver function test results remained normal and HEV RNA was not amplified from either serum or stool.
The graph plots the number of times the ALT level was above the ULN, by date. Genome amplifications of hepatitis B virus and hepatitis C virus were both negative. Other causes of chronic liver disease, including hemochromatosis, autoimmune hepatitis, α1-antitrypsin deficiency, and Wilson disease, were also ruled out. For the serologic and RT-PCR tests, a plus symbol indicates a positive result, a minus symbol indicates a negative result, and a plus/minus symbol indicates a positive test result at the limit of detection of the RT-PCR assay. ALT = alanine aminotransferase; ELISA = enzyme-linked immunosorbent assay; HEV = hepatitis E virus; RT-PCR = reverse transcriptase polymerase chain reaction; ULN = upper limit of normal.
Because ribavirin monotherapy has broad-spectrum antiviral activity against RNA viruses and is rather well tolerated, we investigated its efficacy in 2 immunocompromised patients with biopsy-proven chronic HEV infection lasting for 82 months and more than 12 months, respectively. We observed a normalization of liver function test results after 2 weeks of treatment, and clearance of HEV RNA was attained by week 4 in both patients. To our knowledge, this is the first description of the efficacy of a nucleoside analogue for the management of patients with hepatitis E. Given the absence of available treatment, our results suggest that ribavirin should be tested in larger patient cohorts as a strategy for improving the natural course and management of patients with severe forms of HEV. One limitation of this case report is the lack of long-term follow-up. Clearly, viral eradication is the desired outcome, and evaluation of different dosing and treatment schedules may be required to achieve this goal. Nonetheless, our findings represent the first milestone toward an effective treatment of chronic HEV infection without increasing the risk for graft rejection in transplant recipients or increasing the level of primary or acquired immune deficiency.
Ribavirin is phosphorylated in human cells to ribavirin monophosphate, which is then converted to ribavirin triphosphate. Ribavirin monophosphate inhibits inosine monophosphate dehydrogenase and consequently reduces cellular guanosine triphosphate levels, which can interfere with viral (and host) nucleic acid synthesis. Ribavirin triphosphate directly interacts with the viral polymerase. We observed the same kinetics of normalization of liver function test results and of HEV clearance in both patients—1 of them having received mycophenolate mofetil, which is another inosine monophosphate dehydrogenase inhibitor. This observation could favor a direct inhibition of HEV polymerase by ribavirin rather than an antiviral activity on the basis of guanosine depletion. This hypothesis should be evaluated in vitro (23).
The primary toxicity of ribavirin is anemia. When ribavirin dose is based on weight (800 to 1400 mg/d) and is used in combination with interferon, the reported rate of anemia (hemoglobin level <100 g/L) is 19.3%. Anemia induced by ribavirin is usually mild and may be reversed when dosing is decreased. In the management of chronic hepatitis C virus, this approach obviates the need to interrupt treatment (24). Ribavirin-associated anemia usually occurs during the first 2 weeks of treatment, and the maximum decrease in hemoglobin levels is typically observed during the first 8 weeks. Therefore, close monitoring of hemoglobin levels is mandatory.
The U.S. Food and Drug Administration classifies ribavirin as a category X drug, indicating high teratogenic probability based on animal studies and defined mechanism of action. Hence, the drug is contraindicated in pregnant women. Ribavirin should not be used in pregnant patients with HEV infection because of the preliminary nature of these 2 case reports (25).
In conclusion, ribavirin seems to have potent activity against HEV and should be further evaluated in chronic as well as severe forms of acute HEV infection.
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Disney Cruise Line Stateroom PhotosCategory 8 Pictures
The Category 8 and 9 rooms are considered deluxe outside staterooms (meaning they have a large porthole window.) The category 9 staterooms located on deck 1 have two smaller porthole windows. At 214 sq. ft., these staterooms sleep 3 (with some sleeping 4) and they are among the first categories to book on the ship, as the price on these staterooms is very competitive. Each room contains one queen bed (or two twin beds) a single convertible sofa, and a split-bathroom design. Category 8 staterooms are located on decks 5,6 and 7. Category 9 staterooms are on decks 1 & 2.
Get up to $1000 to spend onboard the Disney Cruise!!
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Today's Theme Park Hours
Tuesday 10/25/2016
Magic Kingdom:
Epcot Future World:
Epcot World Showcase:
Hollywood Studios:
Animal Kingdom:
Typhoon Lagoon:
Blizzard Beach:
9:00 - 7:00
9:00 - 9:00
11:00 - 9:00
9:00 - 7:00
9:00 - 8:30
10:00 - 5:00
10:00 - 5:00
Extra Magic Hour
Evening: Epcot FW
Evening: Epcot FW


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At the recommendation of team doctors, trainers and coaches, Britt is putting away the pads for good and will be a regular student at Auburn until he finishes his degree in criminology.
After having a major surgery to repair what was a worsening shoulder problem followed by long rehab, he was upbeat and ready to challenge for a starting job in spring practice earlier this year. However, on the first day in pads the redshirt sophomore from McEachern High School reinjured the surgically repaired shoulder and couldn't practice the rest of the spring.
After evaluating the situation, discussing it with his father Don Britt and the coaches and staff, everyone concluded that it didn't make sense for the lineman to keep playing football.
"It's really tough to walk away from football and it is not something that I wanted to do, but I at least have the satisfaction of knowing that I gave it my best shot," he says. "Despite the injury, football at Auburn was a great experience for me. I got to know so many great people in the program like the trainers, Arnold Gamber and James Williams who did so much for me.
"Coach Yox (strength and conditioning coach Kevin Yoxall) is just a great person. He called me the other day and we talked for 30 minutes. I can't say enough good things about Coach Nall (Hugh Nall, offensive line coach). He has been absolutely great. Coach (head coach Tommy) Tuberville, of course, has been great, too. I couldn't ask for more supportive people to be around."
Jarrod Britt played offensive guard in seven games as a true freshman in 2003, but redshirted last year while recovering from shoulder surgery.
Britt, who is working this summer at Bill Heard Chevrolet in Columbus, Ga., will be back at Auburn for fall semester classes that start in August. The football program will pay for his scholarship and he plans to join the family's insurance business after graduation.
"I have already decided what I want to do after college," Britt says. "I am looking forward to working with my father."
Britt says that while the shoulder injury will limit him to some degree, he doesn't plan to let it slow him too much. "I like to get out and do a lot of different things and that won't change," he says.
Tuberville says he has a lot of respect for Britt. "Jarrod Britt worked very hard with his rehab and this is a guy who really wanted to play football for us," the head coach says. "We wish he could be part of the team, but it doesn't make sense for him to keep playing football with his shoulder problem."
Britt developed a reputation as a hard-nosed football player and he attacked his rehab following surgery with the same energy he brought to the football. While the Tigers were winning the SEC title last year, he and cornerback David Irons did rehab workouts with a religious fervor in an effort to get ready for the 2005 season. Irons, a cornerback who had ACL surgery last August, is expected to challenge for a starting job this season and Britt is thrilled about that.
"I am so happy that David has made this much progress," Britt says. "It is incredible the amount of effort he has put into his rehab. I saw how hard he worked. He's my home boy and I know he is going to have a great season."
Britt also predicts that despite the loss of three NFL first round draft picks in Jason Campbell, Ronnie Brown and Carnell Williams, the offense will be fun to watch in 2005.
"I think Brandon Cox is going to be really good at quarterback," Britt says. "He was a great recruit coming out of high school and I believe Coach Borges (offensive coordinator Al Borges) will have him ready to go.
"I know a lot of people are worried about how we will replace the two great running backs we lost, but let me tell you, Tre (tailback Tre Smith) and Kenny (tailback Kenny Irons) have a chance to be special. Also, watch out for Carl (tailback Carl Stewart) because he is coming on strong, too."
Up front, the offense will be fine, Britt contends. "Marcus (offensive tackle Marcus McNeill), Troy (offensive tackle Troy Reddick) and Ben (offensive guard Ben Grubbs) are back as starters and they are really good. Marcus and Troy are huge--the two of them are as big as four guys. Coach Nall is a special coach. He'll have them ready to play. Don't worry about the offensive line."
The same can said about Jarrod Britt. Although he will really miss football, he will be just fine, too.


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Lots of good games on today fellas.
Syracuse vs West VA (Geno Smith, Ryan Nassib, Tavon Austin, Stedman Bailey, Alec Lemon...)
Texas vs Oregon State.
TCU vs Michigan State.
Printable View
Lots of good games on today fellas.
Syracuse vs West VA (Geno Smith, Ryan Nassib, Tavon Austin, Stedman Bailey, Alec Lemon...)
Texas vs Oregon State.
TCU vs Michigan State.
For our hypothetical 4-3...how about the undersized DT from Arizona St, Will Sutton as a pass rushing specialist? I having a hard time placing value on him though. 3rd? 4th?
Fella has a good motor and quickness. Figure he'll give Gs fits lined up next to Ngata.
Interesting thought though.
Looking at KC drafting Gino...they have a slower Austin in Mc Cluster (they just don't use him well,) so I think they'll avoid Austin. If they lose Bowe then they'll probably go after a big body to replace him.. especially b/c Baldwin is a bust.
Just say that a player like Fisher, Ansah or Jordan isn't there for them in the first. Imagine if they could trade down into the second, and trade up from their third to a second and snag a trio like Minter, Margus Hunt and Bailey? Wouldn't you just sit there with wet underwear?
A lot of it will probably depend on compensatory picks. If you have those then it gives you more flexibility with your regular picks.
If we can get a third and fourth comp pick, that gives us great manoeuvrability. We can use our original third and fourth to move up in the first, or trade back in the first to second then use them to get a third 2nd round pick and three potential day 1 starters.
Also have the option of making a real bold move. Our first 2nd 3rd 4th and move way up in the first round. And still have a third and 4th round pick, just really lose a second but you could move up and get a potential legit left tackle, or Hankins for nose, teo for ilb, heck even one of the top pass rushers if Kruger goes.
I think I'll be watching the Oregon game.
We need to spend the first 2 picks on D. Can't be ranked #26 again next year - esp w Ray & Ed & Haloti aging...... Come on Oz!!!


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Adam Sachs
Episode 9: Never Mess Up Eggs Again, Editor-in-Chief Smackdown
Episode 9 of the Bon Appétit foodcast features a discussion of common cooking mistakes, and a summit of top food media pros.
I'm Big on Japan
What happens when our resident food fanatic, Adam Sachs, re-creates a Tokyo-style yakitori joint in a one-bedroom apartment in New York City? Smoke, fire, and plenty of sake
The Obsessivore's Beak-to-Tail Duck Dinner Party
So it turns out that 20 Moulard ducks will not fit inside a rolling suitcase. I mention this just in case you happen to be turning 40 and losing your mind—which means you might be planning an alarmingly ambitious dinner party in order to distract your addled brain from this most upsetting of milestones. And... View Article
Reporter's Notebook
In our September issue, we trek out to the hinterlands of Sweden to Faviken Magasinet for a legendary meal. BA Contributor Adam Sachs tells how it happened.


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Even now, knowing all that we do about his deception, Lance Armstrong can be remarkably convincing. As he denies doping allegations in the documentary The Armstrong Lie, you're still halfway inclined to believe him. His conviction is just that persuasive and, consequently, so unnerving. Astute documentarian Alex Gibney (Taxi to the Dark Side) was apparently hoodwinked as well, and he took a rare foray into inspirational storytelling to chronicle the cyclist and cancer survivor's 2009 comeback. But when Armstrong's failed bid for an eighth Tour de France title resulted in him being outed as a cheat, Gibney was forced back to the drawing board. Alas, the finished film often feels like anything but: It's a first draft instead of a treatise. Musings on the "moral relativism" of competition, previously reported details about the complexity of Armstrong's cover-up (including some audacious blood transfusions) and a glut of 2009 Tour footage join Gibney's earnest voice-over, which relates his desire for a reasonable explanation from Armstrong about his deceitfulness. Problem is, Gibney never manages to equal his subject's conviction. Faced with an opponent desperately clinging to the last vestiges of his reputation, Gibney uncharacteristically fails to fully pull back the curtain.
Critic's Grade: C
SEE IT: The Armstrong Lie is rated R. It opens Friday at Cinema 21.


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Are you doing baths or sponge baths? How often?
We are still doing sponge baths, he still has his cord and he doesn't really get dirty anyway. Ofherthan the usual areas, bum, private, neck and face. We are doing sponge baths once every 2-3 days or so. He had one Saturday and we will do one tonight or tomorrow.


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Fantasy FictionGoblins are usually portrayed as ugly mythical creatures that range in size from the size of a hobbit or dwarf to a human. They are usually green or brown and their chief characteristics are:...
Fantasy FictionChanged my nick to minu88 - just in case you want to contact me via enotes.
Fantasy FictionI think as long as a book can be classified as literature, there is room for it in a classroom. I taught a literature course using Jack Finney's Time and Again (which is a time travel novel -- I...
rows eNotes search


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Farmers' Market Finder
You can find us selling individual cuts at these farmers' markets:
Or check with our Google calendar
We're back -> Downtown Palo Alto Farmers' Market!
Gilman Street at Hamilton, Palo Alto, CA
Saturdays 8 am – 12 pm.
(See our Market Calendar for exact dates)
New season at Pescadero Grown Farmers' Market
Starting Thursday, June 2nd – 3 p.m. to 7 p.m.Our dates for this year:
- June 2
- June 9
- July 14
- August 11
- September 8
- October 13
More information about Pescadero Grown: http://www.pescaderogrown.org
(See our Market Calendar to help you plan)
Palo Alto Winter Market – DONE FOR THE SEASON
Hope to see you next season!
Still going strong
Downtown Santa Cruz every Wednesday, 1:30 pm – 5:30 pm
Westside Farmers' Market, Saturday 9am to 1 pm.
View Santa Cruz Westside Farmers' Market in a larger map


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C4 Corvette Gets Powerful New Lease On Life With LS Swap
Here's an LS swap you might not have seen before. Ditching an L98 for an LS is always a step in the right direction. See what it took to get this old C4 updated with modern Chevy power.Read More
Video: Proof That You Can Make Your C5 Better With The Help Of A C6
In the world of LS-swaps, sometimes it seems like the more wild and out-of-the-box the transplant, the better a swap it is. However, Travis and his LS3-swapped C5 prove that even LS-cars can benefit from an LS-swap.Read More
March Performance Eliminates An LS Swap Headache
If you are planning to do an LS swap into your classic ride or street rod, are you prepared to overcome the issue of driving your accessories? March Performance not only has what you need, but they make it easy.Read More
Pace Performance Releases LS/LT 6L Connect And Cruise Packages
Pace Performance has released LS/LT Connect And Cruise Packages. These packages include all the harnesses, programming, hardware & fluids needed for easy install. Check 'em out!Read More
Add Your LS-Powered Vehicle To MSD's Facebook Page
LS power is fitted to all kinds of great cars on MSD's Facebook page. Take a look and you will see Chevelles, Novas, several trucks and even a '69 Barracuda sure to throw a wrench into the minds of the Mopar guys.Read More
Video: Corvette-Powered Factory Five GTM Stretching Its Legs
Who doesn't love a good burnout session? And what about Factory Five kit cars - those are cool too, right? And both together? Awesome. Check out this video to see for yourself.Read More
Video: Ariel Atom Battles Big Z06 on the Nurburgring
Though many would opt for the Atom as the clear choice for a trackday car, the fettled Z06 featured here succeeds in disproving that notion. Read More
SEMA 2015: B&M's New Star Tek Starters Cover Many Applications
Hard starting is a thing of the past with B&M's new line of Star Tek high-torque starters. Applications cover many popular performance engines.Read More
Granatelli Motor Sports Offers 85kv Coil Packs For 05+ Chevys
Granatelli Motor Sports now has 50-state legal 85,000-volt coil packs for 2005-up GM car or truck with current LS and LT engines. These coil packs are strong enough to handle 2,000+ hp engines.Read More
Video: Radical, Mid-Engine, 1000+ HP C2 Corvette
Some Corvette folks think you shouldn't mess with Detroit's DaVincis. On the other hand, if you're gonna do a custom Vette, pull out all the stops and go wild. This1000+ HP mid-engine Vette takes the cake.Read More
In It For The Long Haul: The 650,000-Mile C5 From Florida
Are you a believer in the longevity of Corvettes? After watching this video, you will be. Check out this Torch Red C5 owned by a man named Mark, and the outrageous odometer display that'll leave you speechless.Read More
PRI 2014: PRW Offering PQx Shaft-mount Rocker Arms For LS Engines
PRW now has PQx shaft-mount rocker arms for the LS1, LS2 and LS6 engines. The company also showed off some trick fabricated LS valve covers and machined rocker-cover risers.Read More
V8 Excellence: The Glory and Majesty of the LS Platform
The LS platform has reached the end of the line as far as evolution goes, but we're still not over it. The saga of the landmark V8 that changed the world is recounted here in full, from the LS1 to the LSA.;Read More
The Tale Of Death Vette
This is Death Vette, Trent Durham's insane C5 Corvette project that may suck birds out of the air. Check out the feature to see what makes this car Albuquerques Baddest 'Vette!Read More
Corvette Central Seat Cover Replacement Install on Project Y2K
Project Y2K's interior has yet to be touched, until now - check out our installation experience of Corvette Central's 100% leather seat cover replacements as well as their nifty seat bottom repair kit.Read More
MSD's New Coils and Coil Cover Kits for LS Motors
MSD now offers two sweet new products for LS-powered applications--the newly-redesigned LS coil and LS coil cover. Check 'em out!Read More


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Let the slow cooker do all the hard work with this easy, satisfying White Chicken Chili recipe.
I've been sick this whole week, so all I've wanted to eat is soup and chocolate fudge snack packs.
Yes, that's right. I've been craving those unrefrigerated, flimsy plastic containers of smooth chocolatey goodness all week. Something about being sick makes me long for the comfort foods of childhood. On Wednesday when I was at my worst, I called the Mr. and asked him to make a special trip on his way home just to pick up some snack packs and a can of soup. Licking the chocolate off that plastic lid has some serious healing powers.
Fortunately, the following day I was able to muster up the strength to make a giant crockpot full of this Slow Cooker White Chicken Chili.
Wanna know something guys? Even if you're sick, can barely get out of bed, and weary beyond belief, you have the strength to make this chili.
It is ridiculously easy.
Here's what you do.
Drag your nasty, unshowered, PJ-clad self to the kitchen. Make your husband cut up a few vegetables. Dump chicken breasts, cut vegetables, beans, broth, and spices in the crockpot. Set to low.
Make yourself some tea, take a shot of Nyquil, then collapse on the couch and watch reruns of Boy Meets World for 8 hours in between bouts of fitful, nose-drippy sleep.
Wake to the smell of chicken soup.
Stumble, all zombie like, to the crockpot. Open the lid and take a deep breath in. You're already feeling better, aren't you?
Scoop out a bowl, then take a bite. Feel the rich, warm, broth coat your scratchy throat. Keep slurping. Get all warm and fuzzy inside. Feel better.
It's magic. This White Chicken Chili is magic.
This soup will warm you up on the coldest, roughest days. It's got everything you need for a complete meal, plus tons of great texture from all the different veggies and beans. This soup has a mild heat–the kind that will open up your sinus passages, not the kind that will make you need to drink a gallon of milk.
I've taken a liking to putting coriander in my white chicken chili rather than the more traditional cumin. It adds a similar depth, but the flavor is just enough different to make people wonder what your secret is. If you don't have coriander on hand, cumin makes a fine substitute.
However, there is one spice I have to recommend you add to your cupboards–smoked paprika. I've used the spice in several other recipes on the blog (see this super simple Vegan Lentil Soup, The Best Veggie Burgers Ever, and this Slow Cooker Sweet and Smoky Pulled Pork), and I simply love it. It adds the best subtle smokiness to meats, soups, even eggs. I use it almost exclusively now instead of regular paprika. (Sorry regular paprika!)
The smoky warmth of this dish is just right for a fall evening when you begin to crave something a little heartier. It's a great dish for busy weeknights when the days are shorter, kids are starting sports practice, and the nights call for a sweatshirt. This chili wants to make your life easier (and tastier!)
Serve it up with a dollop of sour cream, smattering of green onions, and plenty of bread for dipping. The whole family will thank you.
Don't forget to check out all the other cozy, warm, fall foods the Sunday Supper contributors are sharing below!
- 1.5 lbs. chicken breast
- 2 stalks celery, chopped
- 3 carrots, chopped
- 1 onion, chopped
- 2 cloves garlic, minced
- 1 red or orange bell pepper, chopped
- 2 teaspoon Kosher salt
- ½ teaspoon pepper
- ½ teaspoon coriander
- 1 teaspoon smoked paprika
- 1 teaspoon chili powder
- ¼ teaspoon cayenne pepper
- 1 can diced green chilies, undrained
- 1 can pinto beans, undrained
- 32 ounces low sodium chicken broth
- Diced green onions (for serving)
- Sour cream (for serving)
- Place all the chopped vegetables at the bottom of the crockpot and the chicken on top. Sprinkle with garlic and remaining spices, add can of green chilies and pintos, then pour chicken broth over all. Cook on low for 6-8 hours then remove chicken and shred with a fork. Return to crockpot and serve soup hot with diced green onions and sour cream.
Recipe by Neighborfood
It's a Sunday Supper Fall Food Extravaganza!
Amazing Breakfasts, Brunches, and Breads
- Apple Spice Muffins from Pixie Dust Kitchen
- Skinny Pumpkin Cinnamon Chip Donuts with Maple Cream Cheese Glaze from The Messy Baker
- Apple Spice Waffles from Treats and Trinkets
- Pumpkin Spice Latte Donuts from Daily Dish Recipes
- Mini Pumpkin Pancake Kebobs from The Urban Mrs.
- Mini Apple Cinnamon Rolls from Peanut Butter and Peppers
- Cinnamon Apple Crepes from Juanita's Cocina
- Maple Apple Bread from The Foodie Army Wife
- Pumpkin Ale Pretzel Buns from A Kitchen Hoor's Adventures
Outstanding Soups, Starters and Sides:
- Bacon, Corn and Shrimp Chowder from The Girl in the Little Red Kitchen
- Pumpkin Tomato Sauce with Andouille Sausage from Hezzi-D's Books and Cooks
- Parmesan Polenta from That Skinny Chick can Bake
- Farro Date Salad with Mango and Arugula from Shockingly Delicious
- Butternut Squash Tian with Herb Topping from Food Lust People Love
- Chipotle Sweet Potato Soup from Alida's Kitchen
Comforting Main Dishes:
- Autumn Risotto with Chicken & Cranberries from Momma's Meals
- Mushroom and Sorrel Lasagne from Jane's Adventures in Dinner
- Roasted Fig & Pancetta Pasta Carbonara from Nik Snacks
- Chili from Casa De Crews
- Vegan Mushroom Pie from Killer Bunnies Inc
- White Pizza with Kale and Meatballs from The Hand That Rocks the Ladle
- Spicy Korean Monkfish Stew (Agu Jjim) from kimchi MOM
- Creole Shrimp & Cheddar Basil Grits Cake from The Roxx Box
- Penne with Spicy Pumpkin and Sausage Sauce from Webicurean
- Bacon Spinach Pasta from Magnolia Days
- Chicken, Spinach, and Gnocchi Soup from Cookin' Mimi
- Stuffed Meatballs in Tomato Alfredo Sauce from Family Foodie
- Butternut Squash and Lentil Pot Pie from Curious Cuisiniere
- Mini Meatball and Goat Cheese Risotto from MarocMama
- Onion Tart {Zwiebelkuchen} from The Not So Cheesy Kitchen
- Slow Cooker White Chicken Chili from Neighborfood
Decadent Desserts:
- Pumpkin Marshmallows from Home Cooking Memories
- Salted Caramel Apple Crisp Bars from Table for Seven
- Apple Cider Five Spice Caramels from girlichef
- Italian Apple Torta from La Bella Vita Cucina
- Apple Fig and Pomegranate Crisp from Take a Bite Out of Boca
- Caramel Apple Sugar Cookie Pizza from Chocolate Moosey
- Pumpkin Bourbon Pie with Walnut Crumble from Gotta Get Baked
- Camotes Enmielados (Mexican Candied Yams/Sweet Potatoes) from La Cocina de Leslie
- Maple Syrup Pumpkin Bars from What Smells So Good?
- Pear Almond Graham Cracker Tart from Vintage Kitchen Notes
- Walnut-Stuffed Baked Apples from Foxes Loves Lemons
- Buttery Bourbon Ice Cream from NinjaBaking
- Caramel Apples from Pies and Plots
- Funnel Cakes from The Texan New Yorker
- Pumpkin Chocolate Chip Oatmeal Cookies from In The Kitchen With KP
- {Gluten-Free} Pumpkin Swirl Pecan Crumb Cake from Cupcakes & Kale Chips
- Chocolate Pumpkin Swiss Roll Cake from Big Bear's Wife
- Hot Apple Pizza from Cindy's Recipes and Writings
- Savory & Sweet Coconut Cream Salted Caramel Apples from Sue's Nutrition Buzz
Tasty Drinks:
- Pumpkin Juice – Harry Potter Style from The Dinner-Mom
- The Best Wines for Fall Foods from ENOFYLZ Wine Blog


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Latest projects
The main objective of SUCCES is to reduce the negative impacts of freight distribution in city urban areas and to reduce its costs. In order to do so, the project focuses on to what extent and how the Supply Chain Management and Construction Consolidation Centres (CCCs) concepts could bring about tested and replicable solutions (adequate collaborative frameworks and, as result, sustainable business models) to address problems in the construction supply chains, focusing on distribution networks, construction sites and reverse logistics. SUCCESS addresses the feasibility of optimising and integrating the supply chain (for example introducing supplier's cooperation schemes, contractors' integration arrangements, introducing optimization tools, etc.).
Key logistics stakeholders from seven European cities/logistics hubs have joined forces to deploy, validate and set-up after project life of five piloted cooperative logistics services combining cooperative mobility services and intelligent cargo with real-life logistical aspects. CO-GISTICS services will increase energy efficiency and equivalent CO2 emissions, bringing additional benefits in road safety and cargo security. To achieve these goals public authorities, fleet operators, freight forwarders, industrial partners and other stakeholders will jointly implement five services: CO2 Footprint Estimation and Monitoring, Multimodal Cargo, Intelligent Truck Parking and Delivery Area Management, Eco-Drive Support, Priority and Speed Advice. These services will be piloted over one year of real life driving.
Energy Production and Distribution (EP&D) networks have rapidly increased their size and complexity. Thus, there is an increasing need of systems supporting the operational, regulatory and design decisions through a highly inter-disciplinary approach, where experts of all the concerned fields contribute to the definition of appropriate mathematical models.
This is particularly challenging because these models require the simultaneous use of many different mathematical optimization tools and the verification by experts of the underlying engineering and financial issues. The COST framework is instrumental for this Action to be able to coordinate the inter-disciplinary efforts of scientists and industrial players at the European level.
ICT services proposed by smartCEM will facilitate vehicle-sharing, public transportation or freight distribution and optimise the performance of EVs, increase public awareness and acceptance, and enhance the confidence of end users towards a new form of mobility: electro-mobility.
The project will prepare, carry-out and coordinate eCall pre-deployment pilots at European level taking into account the the approved standards. The overall project objective for the deployment of the necessary infrastructure in Europe with the aim of making the Pan-European in-vehicle emergency call service eCall a reality.


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|2010-12-10, 16:50
|Link #81
Sage Mode
Join Date: Sep 2008
A couple things: So Madara's mask was white, making it a true combination of the Rinnegan and Sharingan... I thought it was still orange. Without color pages, we'd never know until the anime. It's a little boring for a color scheme, but it makes sense since he wanted both of those eyes. Secondly, the Zetsus have PANTS! Thank God. lol, plant pants.
|2010-12-10, 16:52
|Link #82
Senior Member
Join Date: Oct 2004
Location: Hidden Village of Sake
This guy keeps healing Konoha girls (Hinata, Sakura, now Anko?), if he was not so inhuman i would begin to think that he is somewhat like Itachi, that is he is secretly helping the good guys
But anyway, as expected (for now), Kishimoto wants to save Anko's ass, and so he invents a reason for not killing her now, and later anything can happen, probably Kabuto has a plan to use her which might save her ass.
Summoning type jutsu works by using a large amount of chakra when summoning but none after that. So i assume that Kabuto is able to use it only because he has a huge amount of chakra by becoming a snake-monster like Orochimaru.
Also there are techiques to build up more chakra than one can have naturally, one is Tsunade's chakra seal which can contain huge amount of chakra, an other example was Sage-Naruto's kage bunshins which were accumulating nature energy while the real Naruto was fighting. There's also the cursed seal that forcibly creates chakra. Then there is Kisame and his samehada, they could use other people's chakra. So it's not unprecedented that chakra can come from hidden reserves or from the enemy itself.
I think that the only big disadvantage of Edo Tensei should be that the summoned undead should have a finite amount of chakra that comes from the sacrifice's chakra amount. And when they use jutsu or when they regenerate their body that chakra should be drained, and when it reaches zero the sacrifice should die and the summoned soul return to the "pure world".
So if i had to complain about something it would be the lack of chakra draining of the zombie and the jutsu that controls their will.
|2010-12-10, 17:18
|Link #83
Senior Member
Join Date: Apr 2007
Location: East Cupcake
^Summoning does not require a large amount of chakra. It's a C-Rank jutsu after all. It is only when you summon a very large object/person that more chakra is needed. Just summoning a person, though, shouldn't be too taxing. No, the main, and really only, problem with Edo Tensei si the preparation. You can't simply summon anybody (get it, any body ). There is a detailed set of requirements for every person summoned. Consequently, the down side is not chakra, but rather preparation and then control after the summoning.
So, I believe Kabuto was telling the truth.
|2010-12-10, 18:03
|Link #84
Join Date: May 2004
|2010-12-10, 18:07
|Link #85
Senior Member
Join Date: Oct 2004
Location: Hidden Village of Sake
I don't think that his preparation is a downside for someone like Kabuto or Madara. I mean Orochimaru pulled out from his ass a 1000 ninjas just to train Sasuke a bit, he could have made 500 zombies of those people just like Kabuto made 1 zombie from 2 people in this chapter. So even if they are individually weak he could have made a large zombie army of them just like a Zetsu army is. And then he could have used those zombies against Konoha. Sure Kabuto is better with this jutsu than Orochi was, but there must be some serious limitation otherwise he wouldn't be afraid of Madara right now.
We have seen a spiritual kage bunshin, when Minato and Kushina did talk to Naruto, but it was just a clone of the soul that was powered by a remnant of their chakra and as soon as the chakra was drained it disappeared.
It was clear that Orochimaru's soul was sealed into Itachi's sword, so all other snakes and seal and whatever only contains the chakra.
|2010-12-10, 18:13
|Link #86
Senior Member
Join Date: Apr 2007
Location: East Cupcake
Kabuto described the technique as having no down side, and from everything we've seen, that seems the most likely explanation.
|2010-12-10, 19:33
|Link #88
Join Date: Jan 2009
Location: USA
Age: 30
|2010-12-10, 19:54
|Link #90
floating away...
Join Date: Oct 2007
Location: Beyond World's End
|2010-12-10, 20:55
|Link #91
Ninja Emperor
Join Date: Oct 2004
Age: 31
I like Kishimoto's explanation for the concept of Edo Tensei.
Some people were speculating about how Itachi or Pain's dojutsu could be used if their eyes have been removed. Since Edo Tensei uses the DNA of the corpse no matter how decomposed they are or what part of their body is missing they can still be brought back to life with their full abilities.
|2010-12-10, 23:03
|Link #92
Join Date: Aug 2007
Maybe Kabuto plans using Anko as a new body for Orochimaru? She was probably a candidate for that to begin with.
Now that we know the secrets of Edo Tensei and who Kabuto couldn't summon, gotta wonder who was in that casket that made Madara so afraid.
Madara himself? That's impossible if he's the real Madara. His brother maybe or the original Sage of the 6 Paths? Not a lot of ninjas left unsummoned who Madara himself would fear.
It's interesting Madara mentioned the balance of power against him. We still have no idea how strong he really is.
Now that it's confirmed that Nagato and Itachi have their abilities, who on the side of good have the power to stop either of them?(Outside of Naruto and Bee)
|2010-12-10, 23:38
|Link #93
Join Date: May 2004
But, I do think Kishimoto wouldn't have shown the white snakes unless he intended to do something with them. Even if they were all burnt up, there should be a reason for showing that parts of Orochimaru escaped being sealed away.
|2010-12-10, 23:39
|Link #94
Magical Boy
Join Date: Dec 2004
Location: Hiding... don't try to find me.
Age: 12
|2010-12-10, 23:47
|Link #95
Join Date: Jul 2008
Location: U.S.A.
Age: 28
But the issue have is that, in addition to summoning a soul of the dead into a zombie that can use their techniques, they're also immortal and have a seemingly limitless supply of chakra. I'm sorry, but where is that chakra coming from? And what exactly is making their bodies regnerate?
|2010-12-11, 03:14
|Link #96
Shougi Génération
Graphic Designer
|2010-12-11, 03:44
|Link #97
Senior Member
Join Date: Apr 2007
Location: East Cupcake
Edo Tensei doesn't bother me. It's a faux resurrection technique derived from Buddhist teachings. Hell, it even seems to work off of the Fullmetal Alchemist principles of Equivalent Exchange: one soul for one soul, one body for one body; everything is equal (unlike Nagato's horrendous resurrection abilities which seem to only require chakra). (It certainly helps that the resurrected person is not really alive.)
btw, Can we confirm now that it seems very unlikely that Kabuto summoned forth the original Rikudou-Sennin?
|2010-12-11, 04:02
|Link #99
Join Date: Jul 2008
Location: U.S.A.
Age: 28
Edo Tensei couldn't have less to do with equivalent exchange. One human life, some DNA, a minimal amount of chakra and some weirdass ritual for an immortal zombie with limitless chakra. Sense, this makes none.
|2010-12-11, 04:10
|Link #100
Magical Boy
Join Date: Dec 2004
Location: Hiding... don't try to find me.
Age: 12
Oro is capable of transforming his host body into a powerful ninja just by transferring his soul. Edo Tensei is basically the same thing. Considering he picked Anko once, and how weak she is, it's pretty safe to assume the host's own chakra/powers doesn't matter at all.
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GPS vs. me
... heard that song at least 400 times more than I did.
They have this really cool habit at their house. Every time Leilah falls down and doesn�t hurt herself, instead of gasping and asking if she�s okay, they all start clapping and saying how cool it was. Because if they do that, she doesn�t automaticaly think something is wrong and she won�t cry.
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Day 22 - Palmdale California
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Iron Fist (countermeasure)
Iron Fist (Hebrew: חץ דורבן, Hetz Dorban, lit. Porcupine Arrow) is a hard-kill active protection system (APS) designed by Israel Military Industries (IMI), with a modular design allowing adaptation to a range of platforms ranging from light utility vehicles to heavy armoured fighting vehicles. The concept was revealed by IMI in 2006 and was expected to enter Israel Defense Forces tests by mid-2007. The system has been successfully tested against a wide variety of threats including rocket-propelled grenades, anti-tank guided missiles and tank-fired HEAT ammunition and kinetic energy penetrators.[citation needed]
It senses incoming threats via a fixed radar sensor developed by RADA Electronic Industries and an optional passive infrared detector developed by Elbit's Elisra. When a threat is imminent, an explosive projectile interceptor is launched towards it. The interceptor explodes very near the threat, destroying or deflecting and destabilizing it without detonating its warhead. For this, only the blast effect of the explosive is used. The interceptor casing is made of combustible materials so no fragmentation is formed in the explosion, helping minimize collateral damage.
Acquisition of the Iron Fist active protection system was approved in June 2009. The system was to be installed on the Namer armoured personnel carrier.[1]
In November 2010, The Israeli ministry of defense announced the stop of funding of the system development.[2][3]
In May 2011, the system intercepted Kinetic energy penetrators and Metis anti tank missiles during a test in the U.S.[4]
In early 2013, the MoD tested both the IMI Iron Fist and Rafael Advanced Defense Systems Trophy in a competition to select a single second-generation APS for IDF vehicles. Both systems were first-generation standard at the time. Both systems were financed concurrently until 2010, when the ministry's participation in funding the Iron Fist was suspended and limited procurement of the Trophy was initiated. In 2012, the ministry attempted to combine the two systems into one, utilizing the Iron Fist's interceptor and the Trophy's Elta radar and C3 system. Because Rafael would serve as the prime contractor instead of both companies being equal partners, IMI refused to cooperate. After 2013 trials, completion of a second-generation APS would be completed within a few years. IMI is also trying to market the Iron Fist internationally.[5]
In December 2014, it was revealed that Rafael, Israel Aerospace Industries, and IMI had agreed to jointly develop a next-generation active defense system for vehicles, based on a combination of the Rafael/IAI Trophy and IMI Iron Fist. Rafael will act as the main contractor and system developer and integrator, and IAI and IMI will be subcontractors providing the radar and interceptor respectively. Unlike the Trophy's interception method of metal pellets that spread over a wide area, IMI's interceptor is based on an anti-missile missile. Interest for a vehicle APS grew significantly following Trophy's successful performance during Operation Protective Edge in mid-2014, where tanks equipped with the system intercepted dozens of ATGMs and RPGs, and suffered no injuries or false alarms. The Defense Ministry had pushed the companies to work together and combine their systems.[6]
In June 2016, the U.S. Army chose the Iron Fist Light configuration to protect its light and medium armored vehicles as part of the Modular Active Protection System (MAPS) program. The decision to select Iron Fist was made because of the system's light weight, ability to fire interceptors without shock, and low cost.[7][8]
- ^ "IDF Approves Acquisition of IMI's Iron Fist Active protection Systems for Namer AIFVs". Defense Update. June 2009. Retrieved 10 August 2014.
- ^ Amos Harel (10 November 2010). משרד הביטחון הפסיק לממן פיתוח מערכת הגנה לנגמ"שים [Defense Ministry ceased financing the development of a protective armored personnel carriers]. Haaretz (in Hebrew). Retrieved 10 August 2014.
- ^ Amos Harel (24 December 2010). "הארץ" חושף: מערכת ההגנה מטילי נ"ט מוקפאת, ונגמ"שי החי"ר מחכים למיגון [Haaretz reveals: antitank missile defense system is frozen, and waiting infantry protection APCs]. Haaretz (in Hebrew). Retrieved 10 August 2014.
- ^ "First Report: Iron Fist System Intercepted Kinetic Shell in a Trial in the United States". Archived from the original on May 7, 2011. Retrieved June 8, 2011.
- ^ Rafael's Trophy and IMI's Iron Fist to Compete in Early 2013 - Israeldefense.com, 23 December 2012 Archived October 18, 2013, at the Wayback Machine.‹The template Wayback is being considered for merging.›
- ^ Rafael, IAI and IMI to jointly develop next-generation of active defense system for vehicle - Armyrecognition.com, 30 December 2014
- ^ U.S. has chosen Israeli Iron Fist active protection system to secure armoured personnel carrier - Armyrecognition.com, 9 June 2016
- ^ US Army selects Israel Military Industries for APC active protection system - Jpost.com, 7 June 2016
External links[edit]
- Israel Military Industries Ltd: Active Protection System, Iron Fist
- Armada, issue 4/2007, August/September: Unrivalled Active Protection System (APS) Against the Widest Range of Threats
- "Iron Fist Active Protection Ssystem (sic) (APS)". Defense Update. January 2006. Retrieved 10 August 2014.
|This article related to weaponry is a stub. You can help Wikipedia by expanding it.


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I went on vacation to visit my friends from the home I left before relocating to a different state 2 1/2 years ago. It was so much fun to see my friends again. I spent a day with each person I wanted to see … and it was so invigorating. I felt like I recharged my batteries.
While on vacation, I stayed at my best friend's mom's place – which just happens to be top floor of my best friend's house. It was so nice being able to just go downstairs to spend time with my friend and her family … just like old times. While there, I made some observations that have resonated with me in the week I've been back home. You see, I have struggled with my weight for all of my adult life. I've been trying to lose weight .. yet again .. but have not really been whole-heartedly focussed on it.
One day, her middle son was hungry and had a sweet tooth for some cookies. He stated he just loved cookies. Here's what I observed. He grabbed 3 Oreo cookies and a half glass of milk and went downstairs to enjoy it. Yep, he only grabbed 3 cookies! I'd have likely grabbed 6 cookies!
On another day, I observed my best friend's husband and two youngest kids (one in high school and the other in junior high school) take 2 slices of pizza with a small salad for dinner. WOW! I'd have likely had 3 or 4 slices of pizza and not even considered the salad. Well – that explains why I'm twice the size of ALL of them! <sigh>
Since I've been back home – and today is 1 week – I have lost 4 pounds. This is in spite of it also being the Thanksgiving holiday weekend. In addition to reading some daily scripture meditations/prayers, I also plan to keep these observations on the forefront of my mind to keep my focus on proper portion sizes so I can lose all this excess weight.
I hope you had a wonderful Thanksgiving holiday weekend.


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Posts Tagged: drawing
Drawing History
For the next hour or so, we shifted in our seats, tense and transfixed. It felt like I was witnessing history, a dialogue I'd mostly been exposed to on the internet being brought forth into real life and vocalized by two important people.
The Rumpus Interview with Jason Polan, Part II
Artist Jason Polan talks about drawing in dreams and on wet windows, black-and-white rainbows, and the largest thing he's ever made. ...more
Drawing the Connection
Art is an act of finding, making, and forcing meaning; a synthesis of witness and imagination; a course that veers always toward empathy. ...more
The Rumpus Interview with Craig Yoe
Was Superman's Co-Creator Joe Shuster mad at DC Comics–or even his own creations–for betraying him? Was he taking some sort of delight in putting his characters through this alternate world? (NSFW)...more


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The over-the-counter products are designed to provide short-term relief from minor muscle and joint aches and pains. But regulators say they have received reports of skin injuries ranging from first- to third-degree chemical burns caused by the products. Some of burns have required hospitalization, according to a notice posted to FDA's website.
The agency says consumers should stop using the pain relievers if they experience signs of skin injury, such as pain, swelling or blistering of the skin. Doctors should instruct patients on how to use the products, which come in lotions and patches, correctly.


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