text:
Boilermaker Registration Opens This Weekend
If you're planning to run the Boilermaker road race in Utica this year, you can sign up starting tomorrow. Registration opens for the 15k and 5k runs. Entries are limited to 14,000 runners in the 15k race and 4,000 in the 5k. Sign up online or at Planet Fitness in New Hartford from 8 until noon.


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- Worldwide Rank #6,508
- Follower/Following Ratio 1.56
- Daily New Followers -16
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@CelePistan - Tracking CeleS ツ Twitter profile since August 20, 2011
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subset: commoncrawl


text:
Bad Cat
Bad Cat
May 13, 2004 7:12AM PST
I started working on character sketches for the flash animation I have planned today, but Im stuck. Its hard to believe that for all the painting and drawings I've done, Im having the most trouble drawing the face of a ... cat! WTF, I attempted to draw a simple little cat for hours, looked at pictures, looked at my own cat, googled it... and still it eluded me. Maybe its so hard for me to draw this cat because of its signifigance to the story. Well anyways, I'll try again today.
Comments (0)


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UPS is expanding its network of health care distribution by adding new facilities in Singapore; Venlo, Netherlands; Burlington, Canada; and Louisville, Ky.
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Mendocino to integrate SAP with MS Office
SAP and Microsoft have joined forces to develop a solution that closely integrates Microsoft's Office applications with SAP's...
This Article Covers
Business applications
SAP and Microsoft have joined forces to develop a solution that closely integrates Microsoft's Office applications with SAP's business process software.
How businesses can win talent war with mobile apps, HR data analytics and cloud technology
Latest articles on HR best practices: mobile apps disrupting the annual staff appraisals; reasons for and against open-source software; and Rolls-Royce case study.
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The new product, codenamed "Mendocino", will be designed to make it easier for users to access, analyse and use enterprise data to make better business decisions, according to the pair.
Mendocino will link SAP functionality directly to Microsoft Office applications, and allow users to use familiar Office interfaces to access business information held in SAP products.
As part of the expanded partnership, SAP will resell Microsoft Office and Microsoft will resell licences to SAP's business process platform.
Generally available in 2006, the new product will be released to select customers in the fourth quarter of 2005.
Enjoy the benefits of CW+ membership, learn more and join.
Read more on Business applications
Gulf Air tinkers with Oracle suite and explores hybrid cloud models
'Considerable risk' if Post Office replaced Horizon system, says chairman
SuiteWorld 2016: Focusing on customer experience dragged us away from the call centre, says Aspect
European IT buyers prioritise BI and data management over ERP and CRM


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A Recent Favorite:
Uh Oh, Nothing Here Yet
Why don't you go browse some Comics or Editorials and pick a few to favorite?
Recent Comments
Though the "grayhaired" commenter might deny it, there really is such a thing as racism.
To argue (1) that poverty is purely a matter of individual decisions, caused by spending too much on malt liquor, and (2) that blacks and hispanics make FOUR TIMES as many bad decisons as whites – well, that just tells me that someone's personal circle of acquaintances doesn't include a representative sample of whites, blacks, and hispanics.
But, grayhair, even if you don't personally know any blacks or Latinos, just ask yourself if Donald Trump's wealth owes more to his high IQ & brilliant decision-making, or to inheriting $400 million form his daddy. Then just extrapolate a little bit.
Subprime education is like a subprime mortgage, the scammers don't care if you keep the house or graduate or learn anything, you're just a pawn in their money-leveraging game.
Diploma mills & con men have been around for a long time, and buying friends in government to protect you has a long history too - that doesn't make it right.
Subprime wars in Afghanistan & Iraq are now "under water" & will have to be written off, but have we learned anything? Do we ever learn anything?
Gitmo may not be better than San Quentin in any other way, but if you want to hold random Afghan goatherds forever without charges & without evidence, it is "out of sight."
The guy who hadn't heard the news about Clarence Thomas also needs to read some history – the main impetus for the Constitution was to strengthen the new federal government, not to limit it.
Cheney & Rove must be in a different cell block?
If you made fun of the Old Testament God, you got boils, lightning bolts, and your goats died.
Since we can now make fun of Mr. God & nothing happens, it's pretty good evidence he doesn't exist. Proof is in the pudding.
"Bush was President. But he was not in power."
Yeah right, and Clinton wasn't in power either, and neither of course was Barney Frank. Take off your partisan blinders & notice that both parties bent over backwards from the 80's onwards to please the banks and hedge funds and those who GOT RICH from the credit bubble.
Just follow the money, and it's pretty obvious who maxed out our credit cards and is now putting the rest of us on a diet. (Goldman Sachs etc.) They play, we pay.
Historical footnote: In World War I, many recruits from the French countryside spoke only local patois, not French, and literally did not understand their officers orders (per Graham Robb in "The Discovery of France"). Of course they all got slaughtered anyway, regardless of their language skills - c'est la guerre!
Geekologist, I absolutely agree with you that deregulation and lack of supervision from the SEC were big factors in letting the greed and fraud get out of hand.
My point to DeeBerg was specifically regarding the CRA: (1) that it did NOT apply to the mortgage service companies (2) that it seems to have taken 27 years for the alleged cause-and-effect to suddenly kick in - which seems unlikely, don't you think?


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text:
The game was postponed until Monday with a restart time of 3:05 p.m. CT. The if-necessary game is slated for 6:05 p.m. CT. Both games can be heard on the Sooner Sports Network KREF 1400 AM and seen on ESPN2.
OU's Jonathan Gray struck out nine of 23 batters and allowed just three hits as he finished his start after a one-hour, four-minute lightning delay after the fifth inning. South Carolina starter Colby Holmes was holding Sooners at bay as well, giving up just one hit with two strikeouts.
Gray reached 100 K's for the season with his fourth strikeout, coming in the third inning against Evan Marzilli. He joins Jordan John and Dillon Overton for the first trio in Oklahoma history to each hit the benchmark in a single season.
Rain washed away the standard pre-game routines but the first pitch was on schedule at 6:05 p.m. Central. At 7:26 p.m., officials suspended play. The game resumed at 8:30, but was halted again for heavy rain 10 minutes later at the completion of three outs.
South Carolina won the first game of the best-of-three series, 5-0, Saturday and the two-time defending national champions need just one victory to advance to the College World Series. The Gamecocks have a 20-game winning streak in the NCAA postseason, which began after a loss to the Sooners in the 2010 College World Series.


text:
Hi Guest, welcome to the TES Community!
Connect with like-minded professionals and have your say on the issues that matter to you.
Don't forget to look at the how to guide in the welcome lounge and help forum.
Mathematical Shape Language in EYFS
Discussion in 'Early Years' started by cheeryelle, Sep 11, 2012.


text: First there was Windows vs. Mac. Then came iOS vs. Android. Now with a project called Fuchsa, Google could be starting a new software platform war — but we don't yet know who'son the other side of the battle line. Fuchsa, which emerged Friday, is an operating system designed for "modern phones and moden personal … Read More


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|Welcome to WoWWiki!
|Hello, SilentBob420BMFJ, and welcome to WoWWiki, the Warcraft wiki! Thank you for your contributions, and we heartily encourage you to continue contributing!
Some useful links:
We hope you enjoy editing here and being a WoWWikian!
Quests Edit
Hiya, Bob!
Actually, from my observations, I believe you and the article are both wrong. And yet both right. It's a different answer per server.
On my server, Suramar US, the dailies reset occurs at 4 AM Pacific Time. (That's 7 AM Eastern, New York!) Obviously, your observations can be correct too, for whichever realm it is that you're playing. Perhaps there's one truth here that no one yet has seen entirely. ° talk ˚ contribs. 06:09, 24 June 2008 (UTC)
ok, then i guess put down "early in the am" as the time the day starts.. i watched the clock, and at 2am central time (where i live), my daily quests went from 23 to 25, as i got a message
Cool! Thanks, Bob. Happy questing. ° talk ˚ contribs. 07:55, 24 June 2008 (UTC)


text:
realmagick.com The shrine of knowledge.
Enumeration Computer Science
A selection of articles related to enumeration computer science.
Original articles from our library related to the Enumeration Computer Science. See Table of Contents for further available material (downloadable resources) on Enumeration Computer Science.
- Bringing it Down to Earth: A Fractal Approach
- 'Clouds are not spheres, mountains are not cones, coastlines are not circles, and bark is not smooth, nor does lightning travel in a straight line.' B. Mandelbrot W e want to think about the future - it's our nature. Unlike other creatures, humans possess an...
Mystic Sciences >> Astrology
- Question the Premises of Society and Science
- Question the ultimate validity of the basic premises of society, in particular, scientific theory. Do not accept concepts or statements as truthful simply due to weight of tradition or learned opinion. The synthesis of these statements is a healthy skepticism...
Religion & Philosophy >> Philosophy
- The Religious Experience: A Wiccan Viewpoint
- What is religion? Religion is a set of beliefs which allow us to understand and categorize our world and our place in it. A set of beliefs which define our culture, our expectations, our views of people and behaviors we expect. I have found several different...
Religion & Philosophy >> Religions
- Magick and Science
- Many people wonder how magick works. To the non-believer, they say that there is no proof that spells work. And those abilities such as telekinesis are illusionary or product of imagination. They ask us to use scientific means to explain how exactly these...
Mystic Sciences >> Magick
Enumeration Computer Science is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Enumeration Computer Science books and related discussion.
Suggested News Resources
- Robert Amos: Retro artworks, high-tech lace
- South of the border, the first commercial paint program was written for the Graphic Mac computer in 1984, so Howarth's work was a little ahead of its time.
- The rise of the crime beat "news nerds"
- Still others take a retrospective look at a crime issue, such as the Equal Justice Initiative's exhaustive enumeration of lynching in America. And in a break from convention, many of the projects ...
- Researchers Develop Machines Capable of Detecting Emotion
- I'm afraid that computers will be able to read your mind someday. No joke. Are you afraid?
- How to "Read" A Million Novels in One Afternoon with Spark
- To see how Spark can handle a massive amount of text data, consider the case of a University of Oklahoma doctoral student in Political Science. She wants to investigate ... I'm afraid that computers will be able to read your mind someday.
- Bayesian and Nonlinear Approaches to Statistics
- Learn how rapid data application development can address the data science shortage. Someone ... I'm afraid that computers will be able to read your mind someday.
Great care has been taken to prepare the information on this page. Elements of the content come from factual and lexical knowledge databases, realmagick.com library and third-party sources. We appreciate your suggestions and comments on further improvements of the site.
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and yes i said yes i will yes
Ten years ago we started being married. It is the vow that started our vocation. But what does it mean when a vow becomes an everyday verb? When a calling is shared as a single story? When we think about a wedding, we often think about a beginning. A clean slate for a new couple. An… Read More


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25 Must-Read Nonprofit IT Blogs 2016
You know and love our Must-Read IT Blogs lists, but now, say hello to the nonprofit side.
That little piece of plastic in consumer's wallets that we know as the credit card has truly come a long way. Did you know, for instance, that the idea of payment by card goes all the way back to 1887? Or that American Express and Bank of America issued their first credit cards back in 1966?
Check out this story and more from the week in BizTech below:


text:
Decreased Androgen Receptor Expression Is Associated With Distant Metastases in Patients With Androgen Receptor–Expressing Triple-Negative Breast Carcinoma
To characterize prognostic values of androgen receptor (AR) in triple-negative (TN) breast cancers, we investigated AR expression status and levels, explored an association of AR expression with metastatic disease, and correlated AR expression with Ki-67 in TN invasive breast carcinomas. AR expression was analyzed with immunohistochemistry in 121 cases of TN tumors. Thirty-nine cases had distant metastatic disease and 82 had locoregional disease only. AR was positive in 38 (31.4%) of the 121 cases. Our results indicate that among the AR-positive TN tumors, distant metastases are significantly associated with lower expression of AR compared with cases with only locoregional disease, and that AR expression negatively correlates with Ki-67 expression. These findings suggest that decreased intratumoral AR expression may be predictive of distant metastatic disease and AR expression levels may have potential prognostic value in AR-expressing TN tumors.
- Androgen receptor
- Triple-negative breast cancer
- Distant metastasis
High androgen receptor (AR) expression in breast cancer has been correlated with a low risk of recurrence and death. Significant differences in AR expression have been identified in different molecular subtypes of breast cancer. Triple-negative (TN) breast carcinoma, characterized by estrogen receptor (ER), progesterone receptor (PR), and HER2 negativity, comprises a group of aggressive tumors that characteristically have a low AR expression.1 AR has been shown to have prognostic implications in breast carcinoma, and higher AR expression levels have been associated with older age at diagnosis, higher expression of ER or PR, lower nuclear grades, and smaller tumor size.2,3 Multiple studies have revealed that AR positivity has been detected in approximately half of all breast carcinoma cases.1,2 However, it has been detected much less frequently in TN breast carcinomas (25%-35%).1,2,4-6 Positive AR expression has been associated with favorable outcomes in ER-positive tumors.2 Previous studies looking at AR expression in TN breast carcinoma have demonstrated that AR negativity has been associated with a shorter disease-free interval and overall survival than AR-positive TN cancer.4,7,8 These studies suggest that AR expression could be a useful prognostic marker in TN tumors.
TN carcinomas lack molecular targets commonly used in targeted therapy, making this group of tumors difficult to treat, and chemotherapy remains the main treatment modality.9-11 Conventional neoadjuvant chemotherapy results in complete pathologic response in 13% to 45% of TN tumors, and patients not exhibiting a complete response have a high likelihood of disease relapse.12 Despite having relatively high rates of clinical response to presurgical/neoadjuvant chemotherapy, patients with TN tumors have frequent distant recurrences and a poorer prognosis than patients with non-TN subtypes of breast cancer.13 Fewer than 30% of patients with metastatic TN tumors survive 5 years, and almost all die of their disease despite neoadjuvant chemotherapy.14 The development of novel therapies is crucial to improve the prognosis of TN tumors.
TN breast carcinoma was traditionally considered a distinct, molecular subset of breast carcinoma, but currently it has been proposed that TN breast cancer includes a heterogeneous group of tumors.15 Subtyping TN cancer is necessary to better identify molecular targeted therapies. Lehmann et al15 recently identified 6 TN cancer subtypes using gene expression analysis, including 2 basal-like (BL1 and BL2), an immunomodulatory, a mesenchymal-like, a mesenchymal stem cell–like, and a luminal androgen receptor (LAR) subtype. The LAR subtype was characterized with AR signaling, and expressed numerous downstream AR targets and coactivators. Further characterization of AR expression in TN tumors using immunohistochemistry (IHC) may help better elucidate the molecular basis of TN tumors and provide additional information on prognosis and treatment options for patients with TN tumors that lack specific therapeutic targets.
Recent studies suggest a possible antiproliferative effect of AR stimulation and pathway activation in breast cancer.16,17 High expression of Ki-67, a proliferation index, has been associated with a worse prognosis in TN breast cancer. However, little is known about the correlation status between AR and Ki-67 expression in TN cancers. In this study, we investigated AR expression status and levels in TN breast carcinomas, explored an association of AR expression with metastatic disease, and correlated AR expression with Ki-67.
Materials and Methods
Patient Identification
Patient information was obtained with a search of case files from 2007 to 2010 at the University of Texas Southwestern Medical Center and Parkland Memorial Hospital, Dallas. We included all patients in whom TN breast carcinoma was established with IHC and confirmed with HER2 fluorescence in situ hybridization assay. The criteria for determining triple negativity were based on immunohistochemical staining and image quantitation of ER, PR, and HER2 as previously described.18,19
We identified 163 patients with primary TN invasive breast carcinoma. IHC was performed in 120 of the 163 cases, 1 of which had bilateral primary tumors that were analyzed separately, for a total of 121 cases included in this study. Follow-up data were available for a mean of 30.3 months (range, 1-60 months). The 121 cases of TN breast carcinomas were divided into either distant metastatic disease group (pathologic stage pM1) or locoregional disease group (pM0). Mean follow-up period for the pM1 group was 30.7 months (range, 1-60 months) and for the pM0 group was 30 months (range, 3-60 months).
The locoregional disease group included cases with or without axillary node involvement and with no evidence of distant metastases. Of the 121 cases, 112 (92.56%) were determined to be basal-like TN tumors defined as cytokeratin 5/6 (CK5/6) positivity and/or epidermal growth factor receptor (EGFR) positivity on IHC.
IHC for Tumor Biomarkers
Slides cut from the tumor tissue were immunostained for ER (SP1, prediluted, Ventana Medical Systems, Tucson, AZ), PR (PgR, prediluted, Ventana Medical Systems), HER2 (prediluted, Ventana Medical Systems), CK5/6 (D5/16B4, 1:50, Cell Marque, Rocklin, CA), and EGFR (3C6, 1:2, Ventana Medical Systems). These IHC tests were performed as previously described.18,19
IHC was also used for several additional markers including AR (sc-816, 1:15, Santa Cruz Biotechnology, Santa Cruz, CA), Ki-67 (MIB-1, prediluted, Ventana Medical Systems), and p53 (DO-7, 1:16,000; DAKO, Carpinteria, CA). Immunostaining for AR, Ki-67, and p53 was performed using IHC in conjunction with automated image analysis (ACIS, Clarient, San Juan Capistrano, CA), and all of the results were confirmed on manual review by a pathologist (Y.P.). The ACIS system used for image quantitation consisted of an automated robotic bright-field microscope module, a computer, and a Windows NT (Microsoft, Redmond, WA)–based software interface. The robotic microscope module scanned the IHC-stained slides, and the computer monitor displayed the digitalized tissue images. After viewing the high-magnification images on the ACIS computer, more than 10 subregions of the digitalized tissue images were selected for analysis by the ACIS. To assess the level of AR, Ki-67, or p53 expression, the ACIS provided the percentage of positively stained cells for these markers in the selected subregions. When the percentage of cells staining positive for AR was more than or equal to 1%, the tumor was considered to be positive for AR. Ki-67 and p53 expression was considered to be high when positive cells were more than or equal to 10%.
Statistical Analysis
The frequency of AR expression in the pM1 and pM0 groups was examined using the Fisher exact test. The percentage of intratumoral expression of AR in the pM1 and pM0 groups was compared (data shown as mean ± standard error of mean [SEM]) using the unpaired t test to explore an association of AR expression with metastatic disease in TN tumors. Also, the Pearson correlation analysis was used to correlate AR expression levels with Ki-67 expression, p53 expression, and tumor size. All analyses were performed using GraphPad Prism 5 (GraphPad Software, La Jolla, CA).
Of the 121 cases of TN tumors included in this study, 39 were determined to have distant metastatic disease (pM1) and 82 had evidence of locoregional disease only (pM0). Of the latter 82 cases of local disease, 34 had axillary node metastases. In the pM1 group, 41% of the cases were treated with neoadjuvant chemotherapy before surgery and the most common therapeutic agents used were doxorubicin, cyclophosphamide, and docetaxel; 35% were treated with a partial mastectomy and 65% with a total mastectomy. In the pM0 group, 21% of the cases were treated with presurgical chemotherapy; 62% were treated with a partial mastectomy, and 38% with a total mastectomy. The pM1 cases were more likely than the pM0 cases to receive neoadjuvant chemotherapy.
AR was positive in 38 (31.4%) of the 121 cases. The frequency of AR positivity in the pM1 and pM0 groups was similar, with 10 positive pM1 cases (25.64%) and 28 positive pM0 cases (34.15%, P = .4). There was no significant difference in the rate of neoadjuvant chemotherapy use between the AR-positive and AR-negative cases.
The clinicopathologic characteristics of the pM1 and pM0 groups are summarized in Table 1, and the AR-positive and AR-negative cases are summarized in Table 2. No significant differences were found in the patient age, histologic subtypes, histologic grade, or size of tumor between the pM1 and pM0 groups or the AR-positive and AR-negative groups.
Among the AR-positive cases, the intratumoral expression level was significantly higher in the pM0 group (52.2% ± 7.2%) compared with the pM1 group (19.4% ± 9.1%; P = .02) Figure 1. Of note, 8 of the 10 AR-positive cases with distant metastases (pM1 group) had 20% or less AR positivity Figure 2. Image 1 shows tumor AR immunoreactivity in representative cases in the pM1 and pM0 groups.
Differences in Ki-67 expression levels between AR-positive and AR-negative cases are shown in Table 2. The mean Ki-67 expression among the AR-positive cases (48.4% ± 5.0%) was significantly lower than that of the AR-negative cases (73.1% ± 3.5%; P < .0001) Figure 3. The AR expression levels showed a significant negative correlation with Ki-67 expression in the AR-positive tumors (r = −0.55; P = .0006). No correlation was found between AR expression levels and either p53 expression or tumor size.
Our results reveal that 31.4% of TN breast cancers express AR, which is similar to results seen in previous reports.1,2,5,6,9,20 Among AR-positive TN breast tumors, distant metastases (pM1) are significantly associated with a lower intratumoral expression of AR compared with cases with only locoregional disease (pM0). The results suggest that, among AR-positive TN cancers, the tumors with a higher expression of AR may be less likely to develop metastatic disease. There is no significant difference in the frequency of AR positivity between the distant metastases and the locoregional disease groups in the study.
Androgens have long been thought to play a role in breast cancer, and previous studies have shown that androgens can induce proliferative changes and tumor formation.21 Endogenous androgens inhibit breast development, the effect of which is normally balanced by the stimulatory effect of estrogens.22 Androgens, including testosterone and dihydrotestosterone, function by binding to and activating intracellular ARs. AR expression is abundant in normal breast epithelial cells. However, the functional role of AR expression in breast cancer is not well understood.23
Ki-67 is a proliferative marker with expression peaking during mitosis. The use of Ki-67 as a predictive and prognostic marker in breast cancer has been investigated extensively with higher levels associated with worse prognosis.19,24 Our results demonstrated a negative correlation of AR expression with Ki-67, and a significantly lower Ki-67 expression in the AR-positive tumors than that in the AR-negative tumors, which may be related to the antiproliferative effect of AR stimulation; these findings further support the idea that high AR levels may be associated with a better prognosis in TN tumors.16,17,20
Our results suggest that intratumoral AR expression level rather than the frequency of AR positivity in TN tumors may have potential prognostic value. Decreased intratumoral AR expression is associated with a worse prognosis in AR-expressing TN tumors and may be predictive of distant metastatic disease. In contrast, TN tumors with higher AR expression may have a better prognosis in part due to decreased tumor cell proliferation caused by the increased antiproliferative effect of AR stimulation. Although IHC assessment of AR appears to have significant prognostic value, routine testing for AR in breast cancer specimens clinically is not recommended at this point. Further work is needed to better understand the role of AR expression in tumor metastases.
Our results support the concept that TN breast cancers are a heterogeneous group of tumors with only the minority of cases expressing AR.15 The Lehmann et al15 study revealed that the percentage of TN tumor cells scored with nuclear AR immunostaining and the intensity of the staining were significantly higher in the luminal AR subtype (>10-fold; P < .004) compared with all other TN cancer subtypes. The AR-expressing TN tumors in our study may represent the luminal AR subtype of TN tumors. In addition, their study demonstrated that luminal AR cell lines are uniquely sensitive to bicalutamide, an AR antagonist.15 The AR signaling pathway may be a molecular driver that can be therapeutically targeted in AR-expressing TN tumors, suggesting that AR inhibitor may be a novel therapeutic agent for treating TN breast cancers, especially those tumors not responding to chemotherapy. Knowing the AR expression status of TN tumors is important for the selection of patients with TN breast cancer for antiandrogen therapy.
- © American Society for Clinical Pathology


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Fulton Heights Neighborhood
The FHNA is a non-profit organization made up of neighbors and friends in the Fulton Heights area of Grand Rapids, Michigan. We are one of the older neighborhoods in Grand Rapids lying between Heritage Hill and East Grand Rapids. Even though the Fulton Heights area extends from Eastern Ave to Plymouth Ave, the neighborhood association's boundaries are Fuller Ave, Michigan Ave, Fulton St, and Plymouth Ave. We proactively work with both the Fulton Heights & Michigan Ave Business Districts.
Our Mission
The mission of the Fulton Heights Neighborhood Association is to promote friendship and cooperation among residents; to maintain and improve the property and physical appearance of the community; to assist local businesses to survive and prosper in the community; to have a role in civic matters affecting our community; to develop awareness, a spirit of pride and individuality; to initiate neighborhood programs for solving problems, providing services, and promoting social activities; to encourage the development of more localized groups such as block clubs to follow the aforementioned purposes; and to receive and disburse monies, gifts, bequests and goods for community service for charity.
Latest FHNA News
- 2016 Summer Newsletter September 7, 2016
- FHNA Annual Picnic July 26, 2016
- Preventing Oak Wilt in Grand Rapids April 12, 2016
- Common Ground Church Meeting Survey March 22, 2016
- Common Ground Church Development – UPDATED March 11, 2016


text:
The Pickle
Release Date: January 1st, 1993
R|1 hr. 43 min.
Plot Summary
An unsuccessful director (Danny Aiello) creates a melancholy mess while in New York to preview his science-fiction schlocker.
Cast: Danny Aiello, Dyan Cannon, Clotilde Courau, Shelley Winters, Barry Miller, Jerry Stiller, Chris Penn, Little Richard
Director: Paul Mazursky
Genres: Comedy


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Attorney General Olens' Statement on Fifth Circuit Immigration Ruling
Attorney General Sam Olens today released the following statement on the Fifth Circuit Court's ruling in the case of the Deferred Action for Parental Accountability program:
Attorney General Sam Olens today released the following statement on the Fifth Circuit Court's ruling in the case of the Deferred Action for Parental Accountability program:
Attorney General Sam Olens today announced that former Fort Gordon Youth Challenge Academy Director Lynda Dukes was arraigned on one count of Racketeering (O.C.G.A. § 16-14-4(a)) in Richmond County Superior Court.
Attorney General Sam Olens announced Tuesday that Georgia, along with 23 states filed a lawsuit asking a federal court to strike down the Environmental Protection Agency's (EPA) new source performance standards (NSPS), which effectively prohibits the c
An execution date for Marcus Ray Johnson has been set for November 19, 2015. Georgia Attorney General Sam Olens offers the following information in the case against Marcus Ray Johnson for the 1994 murder of Angela Sizemore:
Attorney General Sam Olens today announced that Georgia, along with 23 other states, filed a lawsuit challenging the Obama Administration's Section 111(d) Rule, an unlawful plan to radically restructure the way electricity is produced and consumed thro
On Wednesday, October 21, 2015, Khiry Price pled guilty in Cobb County Superior Court to Human Trafficking and was sentenced to 50 years to serve 30 years.
Today, October 9, 2015, Attorney General Sam Olens announced that the U.S. Court of Appeals for the Sixth Circuit has ruled in favor of Georgia and 17 other States, and granted a nationwide stay of the EPA's "Waters of the United States" rule.
The lawfully ordered execution of Kelly Renee Gissendaner for the 1997 murder of her husband Douglas Gissendaner was carried out this morning at 12:21am at the Georgia Diagnostic and Classification Center in Jackson, Georgia. The sentence was carried o
Yesterday, Attorney General Sam Olens, Director John Sours of the Consumer Protection Unit, Holly Petraeus, Director of Servicemember Affairs for the Consumer Financial Protection Bureau, and Georgia Watch announced the start of the Georgia Military Co
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Oct 06
Sleep well for good health
Sleep is the one step in my program that is absolutely essential to helping every other step work effectively.
~ Marilu Henner, Total Health Makeover
Marilu calls sleep the fountain of youth. In the Total Health Makeover she says, "if someone told you that you could look younger, feel better, boost your energy level, and keep yourself healthy, wouldn't you want to know how to do that? It's simple, it's cheap, and it's as easy as getting a good night's sleep."
A few facts about Sleep –
- We spend almost one-third of our lives asleep.
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Here's how to assess your sleep health in THM® terms.
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- Advanced * Same as intermediate, plus keep a sleep journal to better track your pattern, including any roadblocks to a good night's sleep.
- Makeover Maniac * Become so obsessed with your journal that you no longer have time to sleep.
Read more about Sleep in Marilu's books.
Total Health Makeover * chapter 12
The 30 Day Total Health Makeover * short summary on pages 67-68
Healthy Kids * what happens to our kids on pages 1-3; bedtime stories on pages 179-181


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Shadoan gave a smile as he put his notebook away. "I'm Shadoan, and Avaith is my pokemon... Like Kiba said, we found you unconscious in the mountains. So we brought you here to get you treated... We have another in our group, but he's busy fighting dragons at the moment..." He dug through his fanny back behind his hip and pulled out Julia's pokemon, all 6 pokeballs and laid them on her lap. "Im guessing these are yours, we found them beside your body when found you." He gave her a kind smile as Avaith grinned and gave a simple bow to Julia as he then turned his attention to his loving mate, Mello."What's your name?"
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realmagick.com The shrine of knowledge.
Slavery In Abrahamic Religions
A selection of articles related to slavery in abrahamic religions.
Original articles from our library related to the Slavery In Abrahamic Religions. See Table of Contents for further available material (downloadable resources) on Slavery In Abrahamic Religions.
- The Religious Experience: A Wiccan Viewpoint
- What is religion? Religion is a set of beliefs which allow us to understand and categorize our world and our place in it. A set of beliefs which define our culture, our expectations, our views of people and behaviors we expect. I have found several different...
Religion & Philosophy >> Religions
- Starting with Jesus and the Christian Path...
- During the years of the historical Jesus' life, there are eight or nine years that his whereabouts are not accounted for. Meaning these are the 'lost' years. It was after returning that he truly began to teach his wisdom. Many scholars believe he was in India...
Religion & Philosophy >> Religions
- The Pagan Origins Of Christian Mythology
- The Judeo-Christian religions were founded in a region of the world where savior religions existed for thousands of years. Much of the symbolism and many of the stories in the Bible may be traced to earlier myths of the Persians, Egyptians, and other people...
Religions >> Christianity & Paganism
- Noah's Ark
- The story (or myth? ) of Noah and his ark full of animals is told from the accounts in the Hebraic Bible, from the Christian's Book of Genesis in the Old Testament Bible and from the Muslim's Qur'an.
Old Testament >> Genesis
- Bibles Do Not Equal Wisdom
- Bibles do not equal wisdom. In other words, all forms of spiritual text no matter how eloquently stated, cannot actually grant wisdom to the reader, merely through the act of reading. Words are only the representations of things, but not the things themselves....
Religion & Philosophy >> Religions
Slavery In Abrahamic Religions is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Slavery In Abrahamic Religions books and related discussion.
Suggested News Resources
- Trump and Cruz's Christian 'Jihad'
- The Republican frontrunners aren't just affirming their Christian credentials, they are also expressing an alleged dichotomy and incompatibility between their Bible-bound religious beliefs and a 'benighted' Islam. ...
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- I am the Lord thy God, who brought thee out of the land of Egypt, out of the house of slavery. • Thou shalt have ... And though each borrow from the Jewish law, the Ten Commandments vary slightly among the branches of the Abrahamic faiths.
- I Am A Pagan – Let The Rant Begin
- I posit that Christianity has dominated religious thought for far too long and has done more damage than it could ever hope to do good, no matter what it's martyrs and evangelists might proclaim.
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Today's Horoscope by Rick Levine
Beautiful Venus forms an anxious aspect to weirdo Uranus, prompting us to desire something or someone far outside the realm of our normal interests. The fiery trine between the lively Leo Moon and Uranus in spontaneous Aries reinforces our revolutionary spirit. However, the cosmos hands us a reality check when cerebral Mercury shifts into take-no-prisoners Scorpio at 4:46 pm EDT, followed by the Moon's entry into efficient Virgo at 11:16 pm.
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ESL is my specialty. I have worked with students of all ages, from over 30 different countries, from absolute beginners learning their very first words to advanced students seeking an additional edge. I have a variety of effective and fun techniques that make learning English easier. I tailor my lessons to meet the needs of each individual student. I help students overcome shyness, pronunciation difficulty, and forgetfulness. I am proud of my record of success on two continents with my ESL students.
Basic grammar through advanced grammar, for native speakers and ESL students. I offer special techniques for understanding how grammar works, applying grammar properly, and checking your own grammar.
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Reading skills for children and adults, native speakers and ESL students. Depending on the needs of the student, I focus on elementary reading ability, standardized test prep, how to read more efficiently and effectively, and speed reading. I approach reading with the notion that reading can be fun, even if it is part of a test. I am very patient with those just beginning to read, and offer creative techniques for improvement.
SAT reading can be challenging for most adults, let alone young people whose vocabularies are still developing. I offer practical ways to analyze written passages, accurately infer meaning, see their structure and organization, and eliminate incorrect answer choices. There are systematic ways to improve SAT reading scores, and my lessons will familiarize you with all of them.
SAT writing can be confusing for adults, let alone high schoolers who are still developing a familiarity with college level writing. I can help students analyze sentences, avoid errors, apply grammar appropriately, and outline and organize essays efficiently. Writing is crucial for success in college; preparing now can give a student a significant edge when test day arrives.
TOEFL is a specialty of mine. Students will understand how the TOEFL tests work, what TOEFL looks for in the written and speaking sections, how to find answers in the reading section quickly an accurately, and how to use selective note-taking to do well on the listening section. I also focus on time management, and how to avoid common mistakes. I also show you how taking TOEFL can actually be fun, and should not be feared. If you are facing a TOEFL test soon, or just want to improve your overall skills, please don't hesitate to make an appointment.
For native speakers and ESL speakers. I offer effective vocabulary techniques that can help you speak English better and more accurately, help you pass your standardized test, improve your reading skills, or give you an edge in business. I can help you determine meaning from context and determine meaning from prefix, suffix, and root. A strong vocabulary makes your writing and speaking much more effective, and helps you get your point across with eloquence.
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SAT English/TOEFL/IELTS/ACT/ESL/ELD/Homework help -- Results oriented


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Your Chromecast may have something special for you today
Google's Chromecast is a handy little tool for streaming media from your smartphone or tablet, but most rarely use it Chromecast outside of casting Netflix or another app on our phone to the TV. If you weren't aware, there's a Chromecast offers page, which provides you with promotional offers from Google, as well as third-party services who want your attention. It doesn't always supply you with fun stuff, but from time to time, you get something cool — and today might be your day.


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|Wine maker notes
|Currently, we offer fine wines under the Sean MinorFour Bears label. I believe youll find these wines to be, as I like to call them, sophisticated yet approachable. The Four Bears wines offer incredible value from distinguished appellations and provide an uncompromising experience.
|We founded Four Bears Winery and Sean Minor Wines in 2005 for a number of reasons. First and foremost, we wanted to make delicious, quality wines that continually exceed your expectations. We are all about family and we named our business for our four children: Nick, Elle, Jack and Charlie. Starting our own winery is both a professional and personal dream. Not long after Nicole and I were married, we discovered our second largest monthly expense was wine. We enjoy wine every day with dinner, when friends and family come to visit, during celebrations. . . actually, I cant think of times we dont enjoy wine. After a number of years in the industry, I knew there had to be a better and more affordable way to produce great wines without severe consequences on the pocket book. We started Four Bears Winery and began producing wines from premier appellations throughout California. With the help of a family friend and colleague, Will Bucklin, our initial production featured a Napa Valley Cabernet Sauvignon, Central Coast Chardonnay, and Dry Creek Sauvignon Blanc. Since then we have expanded our portfolio of wines which include a Sonoma County Sauvignon Blanc, Napa Valley Merlot, Carneros Pinot Noir, Napa Valley Red Blend, Central Coast Pinot Noir and Paso Robles Cabernet Sauvignon. Just as our family and children have grown, so has our business. We decided our winery would eventually include more than one label each with a different focus and personality much like our children. We offer wines under the Sean Minor label and the Sean Minor Four Bears label.


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Machol Pacifica - NZ Israeli Dance
The 26th National Israeli Dance Camp will be hosted by Hamilton in October (Labour Weekend). Preparations are well underway to make this event a success.
Venue: YWCA Hall corner Clarence and Pembroke St, Hamilton
Camp Dates are as Follows...
If you have not already done so, please consider joining the mailing list to get updates as they become available.
Looking for an Israeli dance group in your area? Please visit the Groups page, find your local group and join the movement.


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Hotel Cortezo - Madrid
Free WiFi, a rooftop terrace and gift shops/newsstands are offered at this hotel. The bar/lounge is a perfect place to have a drink. Knowledgeable staff are available at the front desk 24 hours-a-day and can provide express check-in.
Hotel Cortezo - Madrid
Hotel Info: 1-877-214-4288from $81
- Junior Suite, 1 Double Bed
- Double Room Single Use
- Twin Room, 2 Single Beds
- Family Room
- Standard Triple Room, 3 Single Beds
- Quadruple Room
Also popular with travelers from the USA
At a glance
Key facts
Hotel size
- This hotel has 92 rooms
- This hotel is arranged over 6 floors
- Check-in time 12:30 PM-midnight
- Check-out time is noon
- Express check-in
Required at check in
- Credit card or cash deposit required
- Government-issued photo ID required
Travelling with others
- Pets not allowed (service animals welcome)
Extra people
- Roll-away beds available, charges may apply*
- Free WiFi in public areas
- Free WiFi in rooms
- Airport shuttle *
- Self parking *
Other information
- Resort fee included
In the hotel
- Breakfast daily (surcharge)
- Bar/lounge
- Coffee shop/café
- Snack bar/deli
- One meeting room
- 24-hour front desk
- Dry cleaning/laundry service
- Luggage storage
- Number of buildings/towers - 1
- Year Built 1958
- Elevator/lift
- Rooftop terrace
- Accessible bathroom
- In-room accessibility
- Roll-in shower
In the room
- In-room climate control (air conditioning)
- Air conditioning
- Minibar
- Private bathroom
- Shower only
- Hair dryer
- 26-inch LCD TV
- Digital TV channels
- Free WiFi
- Daily housekeeping
- Connecting/adjoining rooms available
Hotel Cortezo - Madrid's small print
Also known as
- Cortezo
- Cortezo Madrid
- Hotel Cortezo
- Hotel Cortezo Madrid
- Medium Cortezo Hotel
- Medium Cortezo Madrid
Cash transactions at this property cannot exceed EUR 2500, due to national regulations. For further details, please contact the property using information in the booking confirmation.
The property has connecting/adjoining rooms, which are subject to availability and can be requested by contacting the property using the number on the booking confirmation.
Mandatory fees
The charges below are included in the total price displayed:
- Resort fee
Optional extras
Self parking costs EUR 25 per day
Airport shuttle service is offered for an extra charge of EUR 30 per vehicle (one way)
We have included all charges provided to us by this hotel. However, charges can vary, for example, based on length of stay or the room you book.
Recent reviews
Good 3.8 /5 from 329 reviews
Too expensive for the quality of service and facilities. No bar!


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Plenty of stories will be shared when these legendary anglers and fathers of the modern fishing industry will come together for the Fishing Legends Panel on February 20th. Don't miss the opportunity to witness and interact with this historic gathering of fishing greats.
Come learn the latest techniques from nationally known anglers at our fishing seminars conducted atop the Hawg Trough. This 5,000 gallon aquarium measuring an astounding 40' long, 4' wide and 8' deep, is one of the show's leading attractions and fits nicely in the heart of Tackle Town. Here visitors can receive expert information from the pros as they watch various seminars conducted throughout the show. Watch in amazement as the best anglers in the country share their secrets and catch fish right before your eyes! Don't forget to check out our speakers page for this year's lineup!
Comedians Pat 'Mac' and Mike 'The Big Cheese' Faverman aren't your average comedians. Pat Mac and Mike Faverman are nationally touring comedians and celebrity chefs with a passion for camp cooking. Co-founders of Ultimate Camp Cooking, Pat and Mike have created a series of DVDs, a popular cookbook, and do live performances around the nation.
Don't miss the opportunity to see these two comedian chefs this year in the Travel Cafe at the Ford Indianapolis Boat, Sport & Travel Show.
K-9 X Games (Shows) are performances by the Alpha K-9 U Crew exhibiting K-9 Obedience & the different Dock-Diving sports disciplines such as X-treme Retrieve, X-treme Vertical and demonstrating the newest discipline, X-treme Air, which will soon be added to the 2016 competition line up – then joining the Alpha K9 U Crew are Invited Handler Teams that will also be demonstrating the well-known "long jump for dogs" (Big Air) in this ever growing and thrilling K-9 sport.
For more information, go to alphak9u.com/events.html
The Travel Café is back with exciting travel destination presentations and videos! Along with the fresh new travel ideas presented by the exhibitors within the Travel & Tourism section of the show, there will be new and unique in-show dining options. The Travel Café will encourage attendees to linger through the use of live and entertaining programs and demonstrations, as well as an array of multi-media displays showcasing destinations represented at the Show. In short you can grab a bite, rest a spell and pick out a new vacation destination all at the same time, this year in the new Travel Café
The Ask the Pros Fishing Seminar Series provides a unique seminar format that puts show goers into direct contact with the seminar speakers. It is an interactive forum, providing invaluable opportunities for seminar attendees to ask the questions most important to them.
Crappie Superstars: Courtesy of B'n'M Poles
Kyle Schoenherr, Russ Bailey, Sam Heaton and Matt Morgan will help folks crack the crappie code on waters from Wawasee to Patoka and everywhere in between.
Dan Armitage – Moderator
The Xpogo Stunt Team is the world's best extreme pogo demo crew, featuring Championship Pro Athletes flying over 10 Feet in the air on extreme pogo sticks. Throwing down flips and incredible tricks, the Xpogo Stunt Team brings the sport to you. The Xpogo Stunt team has headlined in 21 countries, appeared in numerous TV shows, Music Videos, commercials and films, and collectively holds 13 current Guinness World Records.
No need to leave the kids at home. Bring the kids to the Kid's Trout Fishing Pond to try their hand at fishing in Tackle Town.
Test your skills at our 180 foot fly casting pond. From beginners to experts, you'll have the opportunity to speak with the pros who can help you improve your skills or get you started. You can also watch demonstrations from the experts, who are happy to teach you the art of fly casting. Find it in the Quiet Sports and Travel & Tourism Pavilion.
Are you ready for the Rock? This custom designed mobile rock wall stands 24 feet tall and adds a dash of extreme sports to the show! Located in the Quiet Sports and Travel & Tourism Pavilion, the Wall is open to anyone who wants to give rock climbing a try. The Wall has been one of the most popular exhibits at past shows and with the increasing popularity of the X-games, more people will climb the rock wall this year than ever before!
Diver's Supply lets you experience the thrill of scuba diving through their interactive "Discover Scuba" display in the Quiet Sports and Travel & Tourism Pavilion. Under the supervision of a Diver's Supply Professional, you'll experience scuba diving in pool or pool-like conditions. You'll be taught the basic concepts and scuba skills to prepare for your own open water adventure. You'll discover excitement and adventure – freedom and serenity. Nothing compares to the "weightless" exhilaration of breathing underwater. Only a diver knows the feeling! Find out more about them at their website www.diverssupplyindy.com
To celebrate 100 years of Indiana State Parks the DNR has a great series of educational programs designed to teach the public as much as possible about birds and snakes. You won't want to miss these great displays at the show!
The dream of canoeing started for John Van Hal when he was just a kid. After working a few summer jobs, he and his brother had enough money to buy an 18-foot fiberglass canoe. One of his many adventures included a trip down the Des-Moines River from the source in Minnesota to Fort Dodge, Iowa. Even after weathering a tornado less than 1⁄2 mile from their camp he was hooked on canoeing.
John can clearly remember sitting in the boat with his dad, drawing plans for a wooden boat when he was 12 years old. He dreamt of the day when he could build his own. His dreams spawned a reality in 1986, when he built his first redwood strip canoe. During the building process, he realized that he was doing what he loved most, designing and constructing wood strip canoes. He started vanhalcanoes.com which has become a second passion for John. The shop is in Mooresville, IN.
The adventure of exploring new places and enjoying nature around us is something that John has loved since he was a kid. He says "being able to maneuver through a powerful river or a serene lake in a wood strip canoe is indescribable. If you've ever banged around in a metal canoe you'll immediately notice the quietness of a wood strip canoe. My admiration for the outdoors and natural materials is evident in the care that I put into constructing every wood strip canoe."
John Van Hal will be at the show to demonstrate and answer your questions about the building process whether you are building one yourself or are just interested in the process.
One of the great aspects of the Indy Boat Sport &Travel Show is the fact that folks can come and see the Latest, most innovative and up to date gear for outdoor men & women. Our 62nd Indy Boat Sport & Travel Show again is proud to add a special educational element to the event as Jay Walls and Rick Eichrodt will be displaying their Antique Outboard Motors and Boats for anyone who wishes to see how far outboard boat motors have come.
Their display will have over 60 motors, several over 100 years old, and a few factory racing models. Rick and Jay are both local members of the Antique Outboard Motor Club which is an International organization whose fundamental purpose is to provide a means of communication for those who are interested in research and exchange of knowledge pertaining to the history and preservation of antique outboard boat motors. Jay says that during show hours the antique outboard display booth will have knowledgeable club members available who can answer questions about motors or the hobby. Come see this blast from the past at the Indy Boat Sport &Travel Show.


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Fri Aug 19
Use this symbol to remind you of who you are and who you are not...... https://t.co/n3SUrE96FR
Tue Aug 16
Remember not to be the sage as the sage doesn't exist......! Be who you are and allow life to take you.
Sun Aug 07
Meditation helps release the mind of old thought patterns...


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