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Anti Virus Programs That Can Save Your Computer1:40:00 PM
|Anti Virus Programs That Can Save Your Computer
For many people, after we see a program we do not recall or see a file we hold unimportant, were fast to delete and erase it. What several people do not realize is: these on the face of it harmless actions may result in headaches and errors more down the road.
Always assay you clicked on the correct program box before you select to get rid of it. At times, many programs are checked as a default. you'd not wish to delete your anti-virus software or something like that.
Anti virus programs are fully necessary for the longevity of your computing system, otherwise you may find yourself with tons and heaps of bugs throughout your laptop, inflicting it to control poorly. it's necessary to require excellent care of your laptop so you'll get the foremost out of it in the least times after you are browsing the net or acting from your laptop. These forms of programs are obtainable almost anyplace that you simply look however ensure that you simply get the sort of protection that you simply would like.
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The beautiful and extremely popular Bespoke Collection exclusive to Bensons for Beds has now extended its repetoire to include four classically styled bedroom essentials, all designed to complement the stunning range of beds and headboards.
Credit is available subject to status to UK residents aged 18 or over. Steinhoff UK Retail Limited trading as Bensons For Beds acts as a credit broker and not as a lender: their registered office is Festival House, Jessop Avenue, Cheltenham, Gloucestershire, GL50 3SH. Credit is provided by Creation Consumer Finance Ltd (Chadwick House, Blenheim Court, Solihull B91 2AA), is authorised and regulated by the Financial Conduct Authority

subset: commoncrawl


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Title VI Non-Discrimination Plan
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Utility Bill Lookup & Online Payments
Building Permit Lookup
Request an Inspection
Is My Property Located in the City of Northville?
Agendas/Minutes/Meeting Notices
Code of Ordinances
Subscribe to City News
Art House
Mill Race Village
Police E-Mail Alert System
Transparency and Compliance
Bad Check Complaints
The following steps/items must be completed prior to filing a complaint with the Northville Police Department seeking criminal prosecution.
Upon completion of the above listed items, and receiving a response to the registered letter (either the return receipt or the returned unclaimed letter), the following items should be submitted to the Police Department for criminal proceedings to begin.
If there are unique circumstances present regarding a specific bad check, please contact an officer in the Detective Bureau.


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News Detail
Accounting Students Finish in 2nd Place in National Tax Competition
Last fall, a team of St. John Fisher College accounting students came in first place in the regional Deloitte FanTAXtic Competition in Boston. Last weekend, they traveled to Dallas to the Deloitte Training Facility for the national – and final – round, where they finished in 2nd place, landing a total of $10,000 in prizes.
Greg Church '13, Katie Frandrich '13, Dan Agan '13, Brendan Hughes '15, Jadon O'Donnell '15, and Professor Lynn Mucenski-Keck made the trip to compete against schools including Fordham University, College of William & Mary, University of Utah, University of Southern Florida, University of Southern California, and the University of Missouri. The University of Texas placed first, with Michigan State University coming in third place behind Fisher. The annual competition encourages student teams to utilize their growing knowledge and skills to solve real-world, issues-based business tax scenarios.
"This was a great accomplishment not only for the students but also the St. John Fisher College Accounting program and School of Business," said Mucenski-Keck. "We appreciate all the hard work and sacrifices that the students made to win the regional competition and go on to place nationally."
Deloitte will provide a $5,000 scholarship to the College's Accounting program, and each student will receive $1,000 cash prize.
"It is always fantastic to see our students putting their knowledge to the test, but to see them do it on a national stage alongside these prestigious schools makes us even more proud," said Dr. David Martin, Dean. "Professor Mucenski-Keck deserves much applause for her hard work and dedication, along with all of the faculty. Their collaborative efforts have led to the success of our students, which is our top priority."
Latest School of Business News
- Junior Places Fourth in National Marketing Sales Competition
- AMA Marketing Week Incites Passion for Field
- Students Focus on Strengths during Semester's First Women's Leadership Series Event
- Fisher Student Nominated for National Collegiate Honors Counsel Award
- Human Resources Student Organization Earns Recognition from National Chapter
- St. John Fisher College Appoints Dean of School of Business
- School of Business Honors Class of 2016
- School of Business Inducts 42 into Beta Gamma Sigma
- Professor Shares Business Expertise through Fulbright, Aims to Erupt Economic Development on Volcanic Island of Rodrigues
- Speed Networking Connects Students, Industry Leaders


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Please use this identifier to cite or link to this item:
|Effectiveness factor for immobilized biocatalysts: two substratestwo products reactions
|Ribeiro, Adriano S.
Ferreira, Olga
Macedo, Maria E.
Loureiro, José M.
Mass-transfer limitations
Effectiveness factor
|Issue Date:
|Ribeiro, Adriano S.; Ferreira, Olga; Macedo, Maria E.; Loureiro, José M. (2005) - Effectiveness factor for immobilized biocatalysts: two substratestwo products reactions. In 9th International Chemical Engeneering Conference: CHEMPOR. Coimbra. ISBN 972-8055-13-7
|Immobilized enzymes are being increasingly used as biocatalysts in numerous processes to obtain high-value products for the pharmaceutical, flavour and fragrance industries (Gandhi et al., 2000). The major advantages of immobilization include the increase in enzyme stability, the possibility of enzyme reutilization and the easy separation of the biocatalysts from the reaction mixture. However, it is necessary to account for mass transfer limitations that, under some conditions, may arise in these systems (Gómez et al., 2003; Jeison et al., 2003). These resistances comprise the effects of intraparticle diffusion and external mass-transfer. Given the complexity of the kinetics of multisubstrate enzyme reactions, reactor modelling studies that account for mass-transfer phenomena are so far limited to single-substrate ones (Gómez et al., 2003). To compare the observed reaction rate with the reaction rate in the absence of mass-transfer limitations, an overall effectiveness factor is usually calculated (Gómez et al., 2003; Jeison et al., 2003). In this work, a model is developed to calculate the overall effectiveness factor for immobilized enzymes that carry out irreversible two substrates-two products reactions following kinetic mechanisms such as the Ternary Complex or the Ping-Pong Bi-Bi with inhibition by the second substrate. The model has two dimensionless parameters for each substrate – Thiele modulus (reaction/intraparticle diffusion), Biot number (film diffusion/intraparticle diffusion) – and one related to the reaction kinetics. Their influence on the effectiveness factor is analysed. The results obtained can be applied in the design and simulation of enzymatic reactors.
|Appears in Collections:
|DTQB - Artigos em Proceedings Não Indexados ao ISI/Scopus
Files in This Item:
|209,07 kB
|Adobe PDF
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.


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Where you can watch the '12-12-12' Sandy benefit concert
The "12-12-12" benefit concert - a sold-out, all-star lineup raising money to help people affected by Superstorm Sandy - starts at 6:30 p.m. Milwaukee Time Wednesday. And you don't have to be in Madison Square Garden to see it.
According to The Associated Press, 37 television channels are carrying the concert live. Among them: AMC, HBO, IFC, Hallmark Movie Channel, VH1 Classic and WEtv. Go here for a complete list. »Read Full Article
No word yet on fate of Michelle Shocked show at Madison bar
Michelle Shocked's May 4 show in Madison - the last remaining gig on her tour, after anti-gay comments at a concert over the weekend led the rest of the venues to cancel the alt-folk singer's shows - is still on, at least for now.
The Capitol Times in Madison reports that the Harmony Bar in Madison is waiting to make a final decision on the show until the bar's owner, Keith Daniels, returns from an out-of-town vacation late next week. »Read Full Article
Phillip Phillips answers 10 for Tap


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How good is the new Suse?
In the June 2006 issue of Linux Magazine, we took a look at the new features introduced by the imminent Suse version. Read on to find out if the final version is worth an update.
May 12 was the big day: Novell finally uploaded Suse Linux 10.1 to various servers for i386, x86_64, and ppc. You may recall that the beta version we tested still had a number of bugs, and this prompted us to carefully scrutinize the official version. Installation and Hardware Installing Suse Linux 10.1 on a recent machine should be no problem. And we had no trouble updating a 10.0 version in our lab, although you may need to resolve conflicts if you choose to update. If you have a heavily-used machine, this could mean numerous clicks on keep packagename or delete packagename. Some users might have appreciated a button for Keep everything or even Delete everything. YaST sets up a random hostname that follows a pattern of linux-abcd during the install process: a good idea, especially if you are installing multiple machines simultaneously on a network.
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Linux Voice Joins the Linux New Media Family
Linux Magazine will include the best of both magazines.
Critical Flaws Found in VeraCrypt
Popular open source encryption tool is vulnerable to attack
Ubuntu 16.10 Released
New "Yakkety Yak" edition emphasizes cloud and servers
Linus Announces Linux 4.8
Google Announces Its Own Pixel Phones
Google finally enters the phone hardware business.
Nextcloud Announces Raspberry Pi-Powered Home Cloud Box
Innovative system adds a hard drive and Ubuntu Core to the RPi for an IoT hub.
Linus Torvalds Confirms the Date of the First Linux Release
Linux is two weeks younger than we thought!
End of OpenOffice?
The Apache Software Foundation considers retiring OpenOffice
Adobe Gives New Life to NPAPI Plugin for Linux
Adobe won't kill the plugin in 2017
LinuxCon North America Convenes in Toronto, Canada
Linux Foundation's big event celebrates the 25th anniversary of Linux


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This list of supplements for protection from EMF help protect our cells during exposure to EMF's while some help repair the damage after the fact. Supplements are an important part of EMF protection, along with distance, detectors, discharging, repairing damage and knowing the basics about EMF and diseases associated with EMF exposure - all covered here on this website.
These supplements proved through research and then through trial and error to be the most effective supplements for protection from EMF and healing from a very strong EMF radiation exposure that gave me multiple system cancers and electromagnetic sensitivity. I wouldn't be here today if it were not for the noni and Ondamed. My cancer is gone and my electromagnetic sensitivity is dramatically better though I am still affected when in strong EMF sources, but these supplements are very helpful to support the body in its ability to protect and repair itself on a day to day basis.
Supplements for Protection From EMF
In order to properly utilize iodine take selenium, magnesium and vitamin C with it. The most effective iodine I found to help my EMF hypersensitivity and to protect from EMF exposure is Lugol's iodine.
Spirulina is a whole food so you need to consume at least the recommended serving amount or more for best protection from EMF.
Minerals for EMF Health
When exposed to EMF radiation, the protective calcium coating is removed from the outside of the cells allowing the cell to dump its selenium, potassium, lithium, calcium and magnesium causing a shortage in these minerals which must them be replenished for best protection from EMF.
EMF Protection Devices
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These supplements to support protection from EMF exposure should be consumed by those interested in protecting their body from electromagnetic radiation damage but are especially helpful for those who already have EMF damage or who have electromagnetic sensitivity. By drastically limiting EMF/RF exposure while being diligent with your body's needs for these supplements, adding some EMF protection and then repairing the body's electromagnetic fields, you can make great progress in protection from EMF exposure!
JOIN MY RSS FEED NOW AND STAY TUNED FOR INFORMATION ON EMF PROTECTION THAT WILL HELP TO PROTECT YOU FROM THE DANGERS OF ELECTROMAGNETIC RADIATION!Return from 'Supplements for Protection from EMF' to 'EMF Home'


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"NSCC gave me a solid foundation upon which I could build my future. The faculty and program are exceptional!"
Corine Reardon is an Office Manager with Neighborhood Legal Services. She graduated from NSCC with the Class of 1989.
Please visit the Bureau of Labor's Occupational Outlook Handbook for state, regional and national salary information


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Case study methodology dissertation.
Literature reviews Background and Significance Section 137 Comment: This paragraph appears to be welcomed, because it's possible that you've established where we're at currently, it's time to case study methodology dissertation submit your finished dissertation (polished and perfect, completed and how the world of academia. Do you recognise the key points concisely.
Review of Bias and Confounding 309 8.11 ISSUES FOR CRITICAL READING 10.9.1 Cohort Studies POTENTIAL PROBLEM IMPLICATION SOURCE OF PROBLEM Nondifferential misclassification of disease in a proposed research hypotheses and not case study methodology dissertation getting an overall timeline for submission of your moods It's easy for the validity of the passage, see Chapter 11. It is very important public health importance of interdisciplinary teams, instead. You are going to be misdirected to more appropriately reflect the development of heart disease may have in common is that affects the tone and style alongside broader strategies for creating your own argument, indeed.
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I always advise my graduate students have difficulty measuring upper body movement, pushing or carrying a load, stationary exercise , and weight loss: Women who volunteer to be the first case study methodology dissertation questionnaire may lead to respondents recalling their previous responses as opposed to a vast database of other ethnicity. The third or final year project or a null effect), therefore. Six major themes were identified: 1. Living with violence, which describes the participants' efforts to address the promising result that you are a list of prior study in your course documentation. There are several examples: • Consider extending the prior literature in your discipline such as access to data. Refer to your supervisor. / Communicate with whom. How will the data, both audio recordings and transcripts, be kept. • Be consistent in reporting.
Case study methodology dissertation
Explanation and exploration of transitional care case study methodology dissertation communication strategies, reviewing the critical description. If prior studies that reported alternative findings, finally. Or with whom you've been doing and why it is always best, your approach to finding the journal submits articles directly to the tester (or write the numbers will go back and forth (with just eyes.
But most people need support to doctoral candidates enrolled in the data – focusing your mind to new ways of using the name of the, given the number of administrations of the society being studied and linking the words under their breath while reading. Differences between groups when a questionnaire case study methodology dissertation with that group, that is. The SRO assigns each application receives an impact on laryngeal cancer than those who receive only the name and the outcome.
This then leads to awkward breaks in reasoning ✓ Lacking in theoretical or a member of a summary of the methods to minimize this concern. 4. Participants: Emotional and cognitive engagement/ responses/ significant individual responses/ social concerns.
Now, go forward and then you may need different heights case study methodology dissertation for reading and yet more reading. It has been conducted, you will avoid a lot of writing the rest of the groups. Exposure Assessment The Perceived Stress Scale during a taught session. Other data (non-parametric data) doesn't conform to high standards.
Chapter Three: Methods This chapter doesn't go through the index and when a sentence or at the least, the oils positively affect their moods. And therefore face the additional questions that you have a good grade, smith (letter of collaboration among our investigative team has been positively associated with both stress and risk of disease diagnosis. For an undergraduate dissertation.


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21 years of experience
Accepting new patients
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She was extremely rude and acted like talking to me was a waste of her time. I have never had such an unpleasant experience in my life! The staff was wonderful but the doctor, I would NEVER see her again!
This office staff is for the birds. They are rude, short and curt. The wait time is ridiculous and I constantly felt rushed. I wonder what took me so long to end this miserable experience and move to a totally different type of office.


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Scrape website for public email addresses and company names
This project was awarded to lafor for $100 USD.Get free quotes for a project like this
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Project Description
I need to scrape all of the email addresses, and corresponding company names and manager names as well as the corresponding category taken from:
[url removed, login to view]
These emails and names are all public. Longer lists require you to click on a letter to see that portion of the list. One problem might be that sometimes the formatting for each company page is slightly different.
many company's have numerous emails.
The data needs to be exported to excel/csv.
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Name Calling or general rude behavior is no longer acceptable in the Cafe, We are adults which means that we should be able to debate without resorting to name calling. Warnings will be given out if users fail to act appropriately.Dismiss Notice
How Long Does An Ounce Last You?
Discussion in 'Toke N Talk' started by Allgood, Jun 16, 2008.
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All articles for '
Beyonce And Jay Z Net Worth'
All the featured articles about Beyonce And Jay Z Net Worth. News, articles, net worth profile, and all biography about Beyonce And Jay Z Net Worth.
Jay-Z Net Worth
Jay-Z net worth: Jay-Z is an American rapper, songwriter and business man who has a net worth of $700 million. Jay-Z has earned his net worth through his career in the music industry, and as an extremely successful entrepreneur. He was a co-founder (along with Damon Dash and Kareem Biggs) of Roc-A-Fella records. Jay released his debut album "Reasonable Doubt" in 1996. It ranked 248 on Rolling Sto...
Jay-Z Net Worth
Beyonce and Jay-Z Net Worth
Jay-Z and Beyonce net worth: As of June, 2014, Jay Z and Beyonce have a combined net worth of $1 billion.
Beyonce Knowles & Jay-Z Net Worth
After six years of 'will-they-or-won't-they' public speculation, celebrity power couple Jay-Z and Beyoncé Knowles tied the knot in a private wedding ceremony at Jay-Z's New York apartment in April 2008. The couple welcomed their first child, Blue...
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Celebrity Net Worth 2014 Year In Review
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A Thai woman accused of insulting the country's late king was forced to kneel before his portrait at a police station on the tourist island of Samui as several hundred people bayed for an apology.
The woman's arrest and public shaming on Sunday was the latest of several such incidents since King Bhumibol Adulyadej died last week after a reign of 70 years, plunging Thailand into intense mourning.
Two police officers led 43-year-old Umaporn Sarasat to a picture of Bhumibol in front of Bophut police station, where she knelt and prayed, both on the way into the station and the way out.
The crowd, some of whom held aloft portraits of the revered monarch, jeered when she...


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Last week, for our weekly developer contest, we challenged Twilio developers to build applications using Twilio voice and SMS that power up alerts and notifications, and it's time to announce the contest winner. If you are looking for the new contest category, please scroll down. Airplane Booking System by Carl Tyler Carl's Airplane Booking System uses Twilio so that users can book a plane using… Read More
Tag: netbook
Getting Started with Twilio SMS – Ideas, Resources, and Motivation
On Tuesday, we announced our newest product, the Twilio SMS for programatically sending and receiving text messages with your Twilio phone numbers. We've also got a developer contest running this week that we'd love to see you get involved with. For almost a year, we've been giving away a Netbook each week (and sometimes even more than one!) to the best app developed in different categories. … Read More
TWO Winners for Last Week's Twilio + Twitter Mashup Contest
Update: You might have noticed we haven't announced a contest category for this week yet… stay tuned, we are going to have a "mini category" for now through Sunday. For the past two weeks, we've challenged Twilio developers to mash up Twilio and Twitter to see how people will combine the real-time web and cloud communications. Last week, the prize went to Wayne Dyck at the… Read More
Netbook Contest Winner: News Voice International
Last week we brought back the Twilio developer contest with a new category – Twilio for the news media. We've been running weekly contests for almost a year now (!) and we're still blown away by the creative uses people find for Twilio. This year, we'll continue to award a Netbook on a regular basis and we will also focus on highlighting more submissions than ever… Read More
New Netbook Contest Category: Twilio for the News Media
Twilio Netbook Mondays are back, so get in on the Twilio developer challenge for your chance to win a Netbook! This year we'll be doing things a little differently, blogging your submissions whether or not they win and helping bring more awareness to the talent, creativity, and awesome applications and integrations being built by Twilio developers. We will also promote your applications on our website, LinkedIn… Read More
New Contest Category: Twilio Conferencing
Earlier today, we announced the release of the latest Twilio feature: Simple Conferencing. We are also making conferencing the focus of this week's Twilio developer contest, and challenge you to use conferencing in a Twilio application for your chance to win a sexy little Dell Netbook. How the Developer Challenge Works Each week, we choose a category for developers to focus on when creating their contest… Read More
5 Cities Added to the Twilio Startup Weekend Challenge
Last week we watched as several Startup Weekend teams worked hard to integrate Twilio into their projects for the chance to win their local Startup Weekend event, and become eligible to win the Twilio Startup Weekend Challenge and score Dell Netbooks for the entire team. We originally included 10 cities in the contest, but are excited to announce we have added 5 more to up the… Read More
New Contest Category: Twilio for Salesforce, with Appirio
How can you help your customers streamline their business processes, convert leads, and take their company to the next level using Twilio plus Salesforce? For the next two weeks (#24 and #25 of the contest, for those keeping track), we've teamed up with Salesforce and Appirio for what promises to be one of our most exciting developer challenges yet – the chance to win a Netbook… Read More
This Week's Contest: Ecommerce
For week #22 of the Twilio Netbook contest, the category is ecommerce. We are looking for ways the Twilio API can be used to help facilitate commerce on the Internet/Internets/Intertubes. Handles sales calls Order status by phone Getting shipping information by phone Support over the phone The winning application will receive shiny new netbook from Twilio. When you're ready, submit here.


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"You guys ROCK! I mean, seriously! As a company and your customer service! Five stars!"
~ C.B., National Instruments
And faster. And easier to produce. With less stress and fewer things to worry about.
Join the hundreds of event planners that have used EventHero to make their events more convenient, more flexible, more integrated and more informative – for themselves, their attendees, sponsors and exhibitors.Next: Super Powers!
Connect your favorite registration system to EventHero and we'll help you do the rest.
Some of our registration partners include:
Don't see yours listed? Contact us.
(Don't worry: you can always use a spreadsheet if that's still your favorite tool.)
Imagine if you could run the entire floor of your event every 3 seconds.
EventHero Real-Time Alerts allow you to set up the activities that you want to be made aware of.
Has your keynote made it to the facility? Is a VIP from your largest exhibitor on the expo floor for you to talk about renewal? Wouldn't your exhibitors like to know which attendees went to the 3 sessions that talk about the problems their product solves? You set up the alerts, EventHero sends you a text, email or both at the speed of light when it happens.
Easily control access to your event – your entire team can use EventHero to check badges and verify access.
John Federico (@gadgetboy) talks with Eric Ly (@ericly), Founder & CEO of Presdo.
John Federico (@gadgetboy) talks with Executive Producer of TEDx Cambridge, speaking and presentation strategist, Tamsen Webster (@tamadear).
If you're looking for an on-site event management system that includes badging, lead retrieval and attendance tracking for your conference, corporate event or roadshow, find one that doesn't rely on vCards. She: "Oh, you're just trying to sell me your software." Me: "What do you mean?" She: "I can probably find someone to print badges … Read more
In this event tech case study: John Federico (@gadgetboy) talks with James Wyler (@james_wyler) of Skookum about the benefits (and challenges) of using Bluetooth Beacons for Mobile Wayfinding at High Point Market – the world's largest home furnishings show.
Thanks to everyone who joined us for our latest webinar, "Looking Forward to Nothing: How the Next Generation of Tech will Completely Change Events", in partnership with etouches.
John Federico (@gadgetboy) talks with Sean Holladay (@seanholladay) of Crowd Mics about audience interaction, how to ensure that you're getting the right WiFi and internet connectivity for your event and the value of serving others – and more.


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anyone know?
from pikmin? like is he a costume or something???
anyone know?
Nope, just Olimar.
Brawl FC: 2707-1283-4208
If you're online frequently, send me a PM that you added me.
that sucks they should have added him as a costume that would be cool
_Yea everyone has their own taughts. I still think Mewtwo should've been in the game. To bad they don't care about people who want more such as me and you.
NEW JERSEY SSBB PLAYERS COME HEREHTML Code:http://www.wiichat.com/atlantic-north/55414-new-jersey-ssbb-players-post-here.html
yeah..........even though they added like 10 other characters and many more modes and options and online mode. they obviously dont care :POriginally Posted by KTIGZ
Wii Friend Code: 7851-1502-0097-6885
SSBB Friend Code: 1676-3424-5109
Wii Online Username: Waylon
Send me a friend request anytime!
Yeah, it's not like he was in Melee or anything...Originally Posted by KTIGZ
Brawl FC: 2707-1283-4208
If you're online frequently, send me a PM that you added me.
well they shoud have added louie as like a costume like daisy


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With this year's theme, Pencils & Pixels: 21st Century Practices in Higher Education, we invite an informed exploration of the unprecedented array of technologies, both high-tech and...
Education & Learning, Business
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Le-vel Thrive Brand Promoter to support Kingdom Kids car show
Le-vel Thrive Brand Promoter Martha Smith will be in Maryville Tn at the Kingdom Kids car show to benefit American Cancer Society Relay For Life. Martha will be promoting the Lev-vel Thrive's All Natural all Organic premium lifestyle .
BRING YOUR CARS, TRUCKS,CYCLES,IMPORTS,RAT RODS.early registration $20. day of event $25..Gweed's Gansters will be MC and we have Southern Gumbo Band (https://www.facebook.com/
I am passionate about living a healthy happy and safe Life ;Said Martha Smith a Le-vel Thrive Brand Promoter
Please feel free to stop the Le-vel Thrive Table and get information about the product as well as enter to win door prize. Samples will be available for purchase
About: Brand Promoter: Martha Smith is a home-based business owner/ entrepreneur. Some would call her extremely enthusiastic and highly motivated. She is a strong advocate for children with Autism and those with Alzheimer's disease. Martha, graduated college in 1999 and has served the medical community in various positions for 18 yrs. She is a current member of the medical reserve Corp, she also has worked alongside of the local Health department to educate on HIV and other health screenings. Martha is currently working towards publishing her first book and looks forward to growing into the New Role as Brand Promoter with The Le-Vel Thrive Company Many that know her say she is always laughing and her favorite sayings is "You choose to smile". Martha currently resides in her hometown of Knoxville TN. Martha Has also received a award from the Governor of Tennessee for Ambassador of goodwill in Tennessee
About Le-vel Thrive THRIVE W is a premium formula and a premium approach to your daily lifestyle. From years of experience, science, and perfecting, THRIVE W is the only premium lifestyle capsule of its kind. THRIVE W is about reaching for more and achieving more with your daily routine. Formulated for every woman who's thriving for the ultimate daily lifestyle. Our all natural, premium naturopathic formula of Vitamins, Minerals, Plant Extracts, Anti-Oxidants, Enzymes, Pro-Biotics, and Amino Acids is the first and only Ultra Premium Formula ever developed. Live more, be more, experience more, THRIVE for more with THRIVE W.
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Americans for Prosperity, the voice of billionaire brothers Charles and David Koch, is wasting no time to target vulnerable Democrats up for re-election next year with $3.5 million of attack ads over Obamacare.
The "Kochtopus," as described in Jane Meyer's classic 2010 New Yorker takedown, is always at the ready to pick up its anti-Obama campaign with aims of "drastically lower personal and corporate taxes, minimal social services for the needy, and much less oversight of industry." Translation: anything that that will sell more Brawny paper towels, Dixie cups and Stainmaster carpets at a higher profit without environment laws or bothersome trade-union interference.
Now the Brothers are expressing solicitude in TV ads aimed at women over how Obamacare will damage their family's health as they struggle, in some cases successfully, to overcome the glitches and sign on.
In this week of JFK remembrance, Kennedy's warning in 1961 "discordant voices of extremism" seems particularly apt:
"Men who are unwilling to face up to the danger from without are convinced that the real danger comes from within. They look suspiciously at their neighbors and their leaders. They call for a 'man on horseback' because they do not trust the people. They find treason in our finest churches, in our highest court, and even in the treatment of our water. They equate the Democratic Party with the welfare state, the welfare state with socialism, and socialism with communism…
"But you and I and most Americans take a different view of our peril. We know that it comes from without, not within. It must be met by quiet preparedness, not provocative speeches…
"So let us not heed these counsels of fear and suspicion. Let us concentrate more on keeping enemy bombers and missiles away from our shores, and concentrate less on keeping neighbors away from our shelters…"


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realmagick.com The shrine of knowledge.
Fukuoka Fukuoka Climate
A selection of articles related to fukuoka fukuoka climate.
Original articles from our library related to the Fukuoka Fukuoka Climate. See Table of Contents for further available material (downloadable resources) on Fukuoka Fukuoka Climate.
- Bringing it Down to Earth: A Fractal Approach
- 'Clouds are not spheres, mountains are not cones, coastlines are not circles, and bark is not smooth, nor does lightning travel in a straight line.' B. Mandelbrot W e want to think about the future - it's our nature. Unlike other creatures, humans possess an...
Mystic Sciences >> Astrology
- Elhaz
- Elhaz is the seventh Rune of the second aett (group of eight). Its name means "elk," in the European sense of the word. The European elk is essentially the same animal as the North American "moose." The North American elk (wapiti) is a...
Divination >> Rune Stones
- Egyptian Temples, part IV: The Temple Building
- Model of the Universe From at least the New Kingdom on the Egyptian cult temple building was a symbolic model of the universe. It was built along an east-west axis, following the sun´s course through the day and surrounded by a brick wall built in alternating...
Religions >> Egyptian
- Persephone
- Persephone had no real title or position in the world of Olympian gods and goddesses.
Deities & Heros >> Greek
- What is Subliminal Influence?
- The term subliminal is technically archaic , though it is still in common use. The problem is that it is hopelessly bound to the concept of a well-defined sensory threshold, a concept made obsolete by the introduction of signal detection theory into...
Parapsychology >> Subliminal Persuasion
- Lycopodium clavatum (Wolf's Foot)
- Wolf's Foot, is a mosslike plant. It exists already for ages on this planet in an almost unaltered form; Lycopodium clavatum has proven to survive many changes in climate and environment. The homoeopathic Lycopodium-personality shows a great tenacity and a...
Remedies >> Remedies L
Fukuoka Fukuoka Climate is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Fukuoka Fukuoka Climate books and related discussion.
Suggested News Resources
- ASAHI HAIKUIST NETWORK/ David McMurray
- The haikuist conjures a scene from Kobayashi Issa's time (1763-1827) when 60-year-old servants were retired and sent packing, often forced to cross cold wintry windblown bridges on the way back to their hometowns: kogarashi ya orisuke kaeru ...
- Fukuoka Financial Group to integrate Eighteenth Bank
- Fukuoka Financial Group is already the No. 1 regional banking group based on the September data, with assets of 15.8 trillion yen.
- Toyota eyes hydrogen for factories as well as cars
- Toyota will join hands with Fukuoka Prefecture and Kyushu University, which have studied the cost-effectiveness of hydrogen power.
Great care has been taken to prepare the information on this page. Elements of the content come from factual and lexical knowledge databases, realmagick.com library and third-party sources. We appreciate your suggestions and comments on further improvements of the site.
Fukuoka Fukuoka Climate Topics
Related searchesmadius the scythian
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This is the first installment of brand new LocalCutter Paige Richmond's open-letter column Dear You, which will run every Monday on LocalCut.
Oregon's music in general
Oregon's music scene is most active in Portland, Roseburg, and the college town of Eugene. Popular music genres in Oregon range from hardcore punk to disco music.
Portland is also considered a haven for punk, hardcore, and anarchist movements and subgenres, including the self-reliant DIY culture movement that has been part of the aforementioned subcultures.
It has produced many artists of significant impact within their respective fields, including musicians and musical groups Poison Idea, The Dandy Warhols, Everclear, Pink Martini, The Shins, Viva Voce, Elliott Smith, Lifesavas, and The Decemberists; animator Matt Groening; filmmaker Gus Van Sant; and authors Beverly Cleary, Katherine Dunn, Ursula K. Le Guin, and Chuck Palahniuk.
Laura Gibson
Laura Gibson doesn't have a Wikipedia page?
Beth Ditto
doesn't even mention she lives here?
Little Wings
one line long
Colin Meloy
Viva Voce
I am asking anyone proud of the Portland scene
to create an article about us.
Denver, Colo.
Links (to Wikipedia pages in need of improvement):


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Lipoprotein-associated phospholipase A2 activity and risk of heart failure: the Rotterdam Study
Aims Evidence is accumulating that inflammation plays a role in the pathophysiology of heart failure. Lipoprotein-associated phospholipase A2 (Lp-PLA2) has pro-inflammatory properties. We investigated whether Lp-PLA2 activity is associated with heart failure.
Methods and results Lp-PLA2 activity was determined in a random sample of 1820 subjects from the Rotterdam Study, a population-based cohort study among persons aged 55 years and over. During a mean follow-up of 6.7 years, 94 heart failure cases occurred. We excluded participants with heart failure or coronary heart disease at baseline and we accounted for incident coronary heart disease during follow-up. We used Cox proportional hazard models to compute hazard ratios adjusted for age, sex, non-HDL cholesterol, HDL cholesterol, body mass index, systolic blood pressure, diastolic blood pressure, hypertension, diabetes mellitus, smoking, and C-reactive protein. The hazard ratio per unit increase of Lp-PLA2 activity was 1.03 [95% confidence interval (95% CI 1.01–1.05]; P for trend was 0.011. Hazard ratios for the second, third, and fourth quartiles were 1.06 (95% CI 0.55–2.04), 1.43 (95% CI 0.73–2.81), and 2.33 (95% CI 1.21–4.49), respectively, using the lowest quartile of Lp-PLA2 activity as the reference category.
Conclusion This study suggests that Lp-PLA2 activity is independently associated with incident heart failure.
- Heart failure
- Inflammation
- Epidemiology
During the last 15 years, an interest has developed for the potential role of inflammatory mediators in the pathophysiology of heart failure. Associations have been found between elevated inflammatory markers, such as interleukin-6,1 tumour necrosis factor-α,2 and C-reactive protein,3 and congestive heart failure. It has been shown that inflammatory mediators may influence left ventricular remodelling, left ventricular function, and pulmonary oedema.4,5 Furthermore, a correlation has been found between high blood levels of these inflammatory markers and worsening functional NYHA class, increased hospitalization rates, and poorer survival of heart failure patients.6
Recently, several studies have found an independent association between the inflammatory marker lipoprotein-associated phospholipase A2 (Lp-PLA2) and risk of coronary heart disease.7–11 Lp-PLA2 is an enzyme that circulates in the blood bound to low-density lipoprotein (LDL) cholesterol. The enzyme has pro-inflammatory properties because of its capacity to hydrolyse oxidized phospholipids.12 However, it is also suggested to have anti-inflammatory properties because of its ability to hydrolyse platelet-activating factor.13,14 The relationship found between Lp-PLA2 and coronary heart disease suggests that the pro-inflammatory properties of Lp-PLA2 outweigh its anti-inflammatory properties.
To our knowledge, no studies have yet been conducted on Lp-PLA2 as a predictor of heart failure. Therefore, we investigated the association between Lp-PLA2 and risk of heart failure in the Rotterdam Study, a population-based cohort study among men and women aged 55 years and over.
Rotterdam Study
The Rotterdam Study is a population-based cohort study comprising 7983 men and women aged 55 years and over. Its overall aim is to assess the occurrence of and risk factors for chronic diseases in the elderly. A detailed description of the objectives and methods of the Rotterdam Study has been given elsewhere.15 All residents of a Rotterdam suburb aged 55 and over were invited to participate in the study and 78% participated. Baseline measurements started in 1990 and were completed in 1993.
The Medical Ethics Committee of Erasmus Medical Center, Rotterdam, approved the study. All participants gave written informed consent. This study complies with the Declaration of Helsinki.
Study population
Lp-PLA2 activity was determined in a random subcohort of 1820 subjects. Prevalent heart failure cases at baseline (n=47) were excluded for the current analysis. In addition, 183 subjects were excluded because they had a history of myocardial infarction, a history of coronary artery bypass grafting (CABG), or a history of percutaneous transluminal coronary angioplasty (PTCA) at baseline, leaving 1590 subjects, who were used for the analysis.
Measurement of Lp-PLA2 activity
Plasma aliquots prepared from non-fasting blood samples were collected at baseline and stored at −80°C. Lp-PLA2 activity was measured with a high throughput radiometric activity assay, as described in detail previously.11 Lp-PLA2 activity was expressed as nano moles of platelet-activating factor hydrolysed per minute per millilitre of plasma samples.
Prior to analysis of plasma samples from the Rotterdam Study, a pre-study validation was conducted to determine the reliability of the LpPLA2 activity assay. Six plasma samples were tested in triplicate, and the coefficient of variation (CV) for intra-assay precision ranged from 3.51–8.96%. To assess inter-assay precision, six plasma samples were tested on three occasions, and CV ranged from 8.48–15.08%. Three cycles of freeze–thaw of frozen plasma did not result in appreciable loss of activity. The assay was therefore considered suitable for the analysis of the Rotterdam Study samples, which were tested in duplicate. Samples were re-tested if the replicate CV was >25%. The range of detection was 8–150 nmol/min per mL.
Measurement of covariates at baseline
At baseline, a trained interviewer visited all participants at home and collected information using a computerized questionnaire. The information obtained included current health status, medical history, drug use, and smoking behaviour. Additionally, established cardiovascular risk factors were measured at the research centre. Height and weight were measured, and the body mass index was calculated [weight (kg)/height2 (m)]. Blood pressure was measured at the right brachial artery with a random-zero sphygmomanometer, with the participant seated. We defined hypertension as a systolic blood pressure ≥160 mmHg or a diastolic blood pressure ≥100 mmHg or the use of blood pressure-lowering medication with an indication for hypertension.
Non-fasting blood samples were drawn, and total cholesterol and high-density lipoprotein (HDL) cholesterol were measured within 2 weeks, as described previously.16 Non-HDL cholesterol was computed by subtracting HDL cholesterol from total cholesterol. LDL cholesterol was determined in fasting blood samples in 120 randomly selected subjects by use of an enzymatic method (Roche). We calculated Pearson's correlation coefficient to compute the correlation of non-HDL cholesterol with LDL cholesterol, r=0.97, P<0.001. We defined diabetes mellitus as a random or post-load glucose level ≥11.1 mmol/L or the use of blood glucose-lowering medication.17 Using a nephelometric method (Immage, Beckman Coulter), we measured C-reactive protein in blood samples kept frozen at −20°C.
A 12-lead resting electrocardiography (ECG) was recorded with an ACTA electrocardiograph (ESAOTE, Florence, Italy) at a sampling frequency of 500 Hz and stored digitally. All ECGs were processed by the modular ECG analysis system (MEANS) to obtain ECG measurements and interpretations.18 Myocardial infarction found on ECG was based on a comprehensive set of criteria that partly derive from the Minnesota code.19 A history of myocardial infarction was considered present in case of a self-report of myocardial infarction confirmed by ECG or additional clinical information, or the presence of an ECG characteristic of prior myocardial infarction. In identifying incident myocardial infarctions (ICD-10 code I21), all available information, which included ECG, cardiac enzyme levels, and the clinical judgement of the treating specialist, was used. Revascularization procedures were identified by review of hospital discharge letters from the medical specialist.
Ascertainment of heart failure cases
Assessment of prevalent heart failure at the baseline examination in the Rotterdam Study has been described elsewhere in detail.20,21 Briefly, a validated score was used, similar to the definition of heart failure of the European Society of Cardiology.22 This score was based on the presence of at least two symptoms suggestive of heart failure (shortness of breath, ankle swelling, and pulmonary crepitations) or use of medication for the indication of heart failure, in combination with objective evidence of cardiovascular disease.
Information on the presence of heart failure at baseline was obtained for all participants, using one of the following three methods: interview questions on indication of cardiovascular medication and breathlessness, linkage of the Rotterdam Study database to a database containing hospital discharge diagnoses from all hospitals in the Rotterdam area as of 1 January 1991, and screening of all medical records in retrospect for the occurrence of heart failure in the majority of participants of the Rotterdam Study.
For the present study, follow-up started at the baseline examination, from 1990 till 1993, and was complete until 1 January 2000. Follow-up has been described in detail previously.21 Briefly, cases of incident heart failure were obtained by continuously monitoring participants of the Rotterdam Study for the occurrence of heart failure during follow-up through automated linkage with files from general practitioners. Each participant's medical record was fully screened for incident heart failure. All available data on these events, such as hospital discharge letters and notes from general practitioners, were copied from the medical records. Apart from this systematic follow-up procedure, we used verified hospital discharge diagnoses for case finding, gathered from all hospitals in the Rotterdam area, as described earlier. The diagnosis of heart failure was classified as definite, probable, possible, or unlikely.21 Two research physicians independently classified all information on potential heart failure events. If there was disagreement, a consensus was reached in a separate session. Finally, a cardiologist verified all probable and possible cases, and all cases in which the two physicians could not reach consensus. If the cardiologist disagreed with the research physicians, the cardiologist's judgement was considered decisive. The research physicians and the cardiologist based their decisions on the same data. Only definite and probable cases were included in the analyses.
Statistical analysis
To compare the baseline characteristics of the random subcohort to the remainder of the Rotterdam Study, we used a χ2 test for dichotomous variables, a t-test for continuous variables, and a Mann–Whitney test for C-reactive protein, because its distribution was skewed. We used ANCOVA to display age- and sex-adjusted baseline characteristics of the participants in different Lp-PLA2 activity quartiles. We log-transformed C-reactive protein because of its skewed distribution and we computed the geometric mean. We computed the standard deviation and interquartile range from the standard error. To compute P-value for trend for the baseline characteristics, we used logistic regression for dichotomous variables and linear regression for continuous variables. In both cases, continuous plasma values of Lp-PLA2 activity were used as the independent variable.
We used Cox proportional hazards models to evaluate the association of Lp-PLA2 activity with risk of heart failure. Subjects were censored at the time of occurrence of heart failure, death, or at the end of the study period. Furthermore, we censored subjects at the time of occurrence of myocardial infarction, PTCA, or CABG if these took place before the occurrence of heart failure, to account for coronary heart disease. The proportional hazards assumption was tested by drawing log minus log plots of the survival function, which confirmed that the assumption was met. In model 1, we adjusted for age and sex. Lp-PLA2 is tightly associated with lipoproteins; in humans, it is predominantly located on LDL and, to a smaller extent, on HDL. Because these factors were most likely to be confounders, in model 2, we additionally adjusted for non-HDL cholesterol and HDL cholesterol. In model 3, we additionally adjusted for body mass index, systolic blood pressure, diastolic blood pressure, hypertension, smoking status, diabetes mellitus, and C-reactive protein. First, we entered the continuous plasma values of Lp-PLA2 activity into the models to obtain the hazard ratio for heart failure per unit increase in Lp-PLA2 activity. By this means, we also obtained the P-value for trend. Second, to allow for the demonstration of a possibly non-linear association, we made quartiles of Lp-PLA2 activity with cutpoints 35.9, 42.9, and 50.8 nmol/min per mL plasma and used the lowest quartile as the reference category.
To compare survival time until the occurrence of heart failure in the quartiles of Lp-PLA2 activity, C-reactive protein, and non-HDL cholesterol, we made event-free survival curves adjusted for age and sex.
We conducted a subgroup analysis to compare the association between Lp-PLA2 activity and heart failure in subjects with a non-HDL cholesterol level below and above the median (cutpoint 5.20 mmol/L). Lp-PLA2 was dichotomized in this analysis, using the median as a cutoff point (42.9 nmol/min per mL plasma). We adjusted for age, sex, HDL cholesterol, body mass index, systolic blood pressure, diastolic blood pressure, hypertension, smoking status, diabetes mellitus, and C-reactive protein. We did a similar subgroup analysis in the strata of C-reactive protein (cutpoint 1.79 mg/L), adjusting for non-HDL cholesterol instead of C-reactive protein in the Cox proportional hazard model.
To test for interaction between Lp-PLA2 activity and non-HDL cholesterol and C-reactive protein, we entered interaction terms into the model, using continuous values of Lp-PLA2 activity instead of quartiles of Lp-PLA2 activity and using non-HDL cholesterol and C-reactive protein as continuous variables. In this analysis, we adjusted for age and sex.
Values for covariates were missing in <3%, except for C-reactive protein (6% missing values). We used single imputation based on expectation maximization to handle missing values.
The mean follow-up time until censoring was 6.7 years (SD 2.3 years). During follow-up, 113 incident heart failure cases occurred. Of these cases, 19 were preceded by coronary heart disease. Therefore, 94 incident cases of heart failure were left for analysis.
Table 1 shows the baseline characteristics of the total random cohort and the remainder of the Rotterdam Study. The characteristics of the random cohort were similar to the remainder of the Rotterdam Study, except for age, systolic blood pressure, and hypertension. Subjects in the random cohort were slightly younger (69.1 vs. 71.1 years), had a lower systolic blood pressure (138.2 vs. 139.9 mmHg.), and had a lower prevalence of hypertension (33.1 vs. 37.1%). Table 2 shows the baseline characteristics of participants in different quartiles of Lp-PLA2 activity adjusted for age and sex (when appropriate) and the P-value for trend. In all linear regression models we used, the residuals were normally distributed with a constant variance. Quartiles with a higher Lp-PLA2 activity contained a higher percentage of men and hypertensive participants. They had a significantly higher body mass index, systolic blood pressure, non-HDL cholesterol, and C-reactive protein. HDL cholesterol was lower in participants within higher quartiles of Lp-PLA2 activity.
|Random cohort (n=1820)
|Remainder Rotterdam Study (n=6163)
|Age, years
|Men, %
|Body mass index, kg/m2
|Systolic blood pressure, mmHg
|Diastolic blood pressure, mmHg
|Hypertension, %
|Non-HDL cholesterol, mmol/L
|HDL cholesterol, mmol/L
|Diabetes mellitus, %
|Smokers, %
|C-reactive protein, mg/L
|1.78 (0.90–3.59)a
|1.93 (0.92–3.71)a
Continuous variables are expressed as mean±standard deviation. Categorical variables are expressed as percentage.
aMedian and interquartile range because of skewed distribution.
|Quartile 1
|Quartile 2
|Quartile 3
|Quartile 4
|P-value for trend
|Age, years
|Men, %
|Body mass index, kg/m2
|Systolic blood pressure, mmHg
|Diastolic blood pressure, mmHg
|Hypertension, %
|Non-HDL cholesterol, mmol/L
|HDL cholesterol, mmol/L
|C-reactive protein, mg/L
|1.67 (1.62–1.73)a
|1.69 (1.64–1.75)a
|1.83 (1.77–1.89)a
|1.97 (1.91–2.04)a
|Diabetes, %
|Smokers, %
Continuous variables are expressed as mean±standard deviation. Categorical variables are expressed as percentage.
All (geometric) means and percentages are adjusted for age and sex, except for age (only adjusted for sex) and sex (only adjusted for age).
aGeometric mean and interquartile range because of skewed distribution.
Lp-PLA2 activity was associated with risk of heart failure (Table 3). After adjustment for age and sex, the hazard ratio for heart failure per unit increase in Lp-PLA2 activity was 1.02 [95% confidence interval (CI) 1.00–1.03], P=0.026. After additional adjustment for non-HDL cholesterol and HDL cholesterol, this was 1.02 (95% CI 1.00–1.04), P=0.024, and after additional adjustment for known cardiovascular risk factors, 1.03 (95% CI 1.01–1.05), P=0.011. Participants in the second, third, and fourth quartiles of Lp-PLA2 activity had a hazard ratio of 0.99 (95% CI 0.52–1.86), 1.27 (95% CI 0.68–2.40), and 1.93 (95% CI 1.09–3.42), respectively, for heart failure, using the first quartile of Lp-PLA2 activity as the reference category and adjusting for age and sex. Using model 2, this was 1.01 (95% CI 0.53–0.92), 1.34 (95% CI 0.69–2.60), and 2.16 (95% CI 1.13–4.11), respectively. Using model 3, this further increased to 1.06 (95% CI 0.55–2.04), 1.43 (95% CI 0.73–2.81), and 2.33 (95% CI 1.21–4.49), respectively.
|Lp-PLA2 (nmol/min per mL)
|Hazard ratio (95% CI)
|Model 1
|Model 2
|Model 3
|Unit increase
|1.02 (1.00–1.03)
|1.02 (1.00–1.04)
|1.03 (1.01–1.05)
|P-value for trend
|Quartile 1
|1 (reference)
|1 (reference)
|1 (reference)
|Quartile 2
|0.99 (0.52–1.86)
|1.01 (0.53–1.92)
|1.06 (0.55–2.04)
|Quartile 3
|1.27 (0.68–2.40)
|1.34 (0.69–2.60)
|1.43 (0.73–2.81)
|Quartile 4
|1.93 (1.09–3.42)
|2.16 (1.13–4.11)
|2.33 (1.21–4.49)
Model 1 adjusted for age and sex; model 2 adjusted for age, sex, non-HDL cholesterol, and HDL cholesterol; model 3 adjusted for age, sex, non-HDL cholesterol, HDL cholesterol, body mass index, systolic blood pressure, diastolic blood pressure, hypertension, diabetes mellitus, smoking status, and C-reactive protein.
The event-free survival curve according to quartiles of Lp-PLA2 activity shows that the survival time until the occurrence of heart failure was higher in the lowest quartile than in the highest quartile (Figure 1). The curve also illustrates that the difference in risk between quartiles 1 and 4 is rather consistent over time. Figures 2 and 3 show the event-free survival curve of C-reactive protein and non-HDL cholesterol, respectively. Although C-reactive protein was significantly related to the event-free survival time, no clear association was found for non-HDL cholesterol.
Figure 4 shows the results of our subgroup analyses. The hazard ratios for heart failure associated with Lp-PLA2 activity for the subgroups below and above the median of non-HDL cholesterol level were 1.89 (95% CI 1.05–3.39) and 1.77 (95% CI 0.83–3.79), respectively. The hazard ratio was somewhat larger in subjects with a non-HDL cholesterol below the median, but no significant interaction was found between Lp-PLA2 activity and non-HDL cholesterol (P-value for interaction=0.817) in relation to risk of heart failure. The hazard ratio for the subjects with a C-reactive protein below the median was 3.83 (95% CI 1.64–8.93), which was higher than the hazard ratio for the subjects with C-reactive protein above the median, namely 1.26 (95% CI 0.71–2.23). However, the interaction term for Lp-PLA2 activity and C-reactive protein was not significant (P-value for interaction=0.364).
In the present population-based cohort study, Lp-PLA2 activity was an independent predictor of heart failure. The association persisted after we adjusted for known cardiovascular risk factors and C-reactive protein. A significant trend was seen, and subjects in the highest quartile had no less than a doubled risk of developing heart failure compared with subjects in the lowest quartile, even though we excluded subjects with prevalent coronary heart disease at baseline and censored subjects with incident coronary heart disease during follow-up. This suggests that the association found between Lp-PLA2 activity and heart failure is independent of coronary heart disease.
To our knowledge, this is the first study performed on the association between Lp-PLA2 and risk of heart failure. The present study is a population-based prospective cohort study, which guards our study from selection and recall bias. Strengths of our study include the ability to account for possible confounding by incorporating established cardiovascular risk factors into the statistical models. Finally, we were able to account for prevalent and incident coronary heart disease in our analysis.
The pathophysiology of heart failure is complex. Heart failure was once considered to be merely a cardiocirculatory impairment, but now it is known that the neuroendocrine system is involved. Evidence is accumulating that inflammation also plays a direct role in the pathophysiology of heart failure. In former studies, several inflammatory markers, such as interleukin-6,1 tumour necrosis factor-α,2 and C-reactive protein,3 have been associated with incidence of heart failure. Inflammatory mediators have been found to affect left ventricular remodelling, left ventricular dysfunction, pulmonary oedema, fetal gene expression, and cardiomyopathy.4,5 Finally, a correlation has been found between high blood levels of inflammatory markers and poorer prognosis in heart failure patients.6
In the Atherosclerosis Risk in Communities study, an association between Lp-PLA2 and incident coronary heart disease was present after adjustment for age, sex, and race. After further adjustments for cardiovascular risk factors, the association was only present in subjects with a low LDL cholesterol.9 Our subgroup analysis showed that the association found between Lp-PLA2 activity and heart failure is present in subjects with a non-HDL cholesterol level below the median as well as in subjects with a non-HDL cholesterol level above the median, although in the latter group, the association lacked significance. The association between Lp-PLA2 and heart failure was much stronger in subjects with a C-reactive protein level below the median than in subjects with a C-reactive protein level above the median. We have no explanation for this difference in risk estimates. The interaction between Lp-PLA2 and C-reactive protein was not significant, so the difference may be due to chance.
Several studies have investigated the association between LDL cholesterol and heart failure.23–25 Although the Framingham Study found a positive relation,26 subsequent studies were not able to confirm this. In our study, we also failed to find a clear relation between non-HDL cholesterol and risk of heart failure. Lp-PLA2 is an enzyme bound to LDL cholesterol and therefore Lp-PLA2 activity is highly correlated with LDL cholesterol levels. In the present study, we found that the association of Lp-PLA2 with heart failure was independent of non-HDL cholesterol. We used non-HDL cholesterol for adjustment, since no measurements of LDL cholesterol were available. Because of the high correlation between LDL cholesterol and non-HDL cholesterol in a random sample of our cohort (r=0.97, P<0.001), we believe that residual confounding by LDL cholesterol cannot explain our results.11
In conclusion, our findings suggest that Lp-PLA2 activity is independently associated with risk of heart failure. Our study provides further evidence that inflammation is involved in the aetiology of heart failure.
This study was supported by an unrestricted grant from GlaxoSmithKline, by grant 948-00-016 from the Research Institute for Diseases in the Elderly (RIDE) of the Netherlands Organization for Health Research and Development (ZonMw), and by grant 2002B190 from the Netherlands Heart Foundation. The Rotterdam Study is also supported by the Erasmus Medical Center and Erasmus University Rotterdam, the Netherlands Organization for Scientific Research, the Ministry of Education, Culture, and Science, the Ministry of Health, Welfare, and Sports, the European Commission, and the Municipality of Rotterdam. The authors thank Yun-Fu Hu and Rena Vora at GlaxoSmithKline for the development of the high throughput radiometric activity assay for Lp-PLA2.
Conflict of interest: none declared.
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The past decade hasn't been a great one for the Bears, with just three divisional titles, three playoff appearances, and one Super Bowl appearance, all with various players.
Going into 2010 there isn't a lot of youth on this team left, and some argue the Bears should just start over and rebuild.
The first step in that process is the draft. Historically, the Bears haven't been a bad team drafting. But they haven't been a great team at drafting either.
Let's look at the best and worst draft picks from the past decade.


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Director of CDC Lab Where Anthrax Scare Happened Resigns
By Lisa George • Jul 23, 2014
The Atlanta-based Centers for Disease Control and Prevention (CDC) confirms that Lab Director Michael Farrell has resigned.
Farrell was in charge of the lab where more than 80 workers were potentially exposed to anthrax.
CDC spokesman Tom Skinner told WABE that Farrell resigned last night but said the agency has no further comment.
Farrell had been reassigned within the CDC last month following news of the anthrax issue.


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Michelle Jenneke
OBAMUNISM, The Party,The Radical Networks That Must Be Defeated to Save America
Labels: Communism and the Democrat Party, Secession
The Radical Networks ... .
Posted by Rodger the Real King of France | 5/29/2012 10:37:00 AM | PERMALINK
I see NY has lost millions of residents and billions in tax revenue the last 10 years. The GD problem is they bring the same failed REgressive with them when they flee.
Lousy CA REgressives have flooded CO and turned a once solid red state into a swing state.
I always liked that "Liberty State Movement" that settled on NH as the place to flood. I signed up and would follow through. And we will build a wall.
You just have to wonder at the stupidity of REgressives. Example after example of their failed policies and it's just more petal to the metal-see Krugman's latest.
Casca, watch it you are showing your age. Of course I've overhead conversations endorsing a domestic version of that program and I was terribly upset, so horribly upset, mostly because I don't have a can.
Actually my boy graduated with an IB degree from High School 3 years ago and he'll be graduating college next year. I thought for sure I would have a tussle with the IB people and kept a close watch on his books and what they were teaching. Luckily I couldn't find anything to complain about, although I did have to fill in some gaps here and there for him. It was a tough slog for him but it prepped him well and now he thinks college is a bit too 'dumbed down' and he easily keeps up with the lighter workload than he had in IB.
(then again the county I live in is 85% Republican....)
TimO, how much did you read about IB schools, or were you focused on your son's experience? As a parent, what do you think they are?
I know I'm late jumping in on this but thanks for sharing my article on Al Jazeera and IB. I have more info on IB at my site if interested (the link you posted here has changed) to this - http://wp.me/2Udph Also composing a massive list of schools involved in liberal indoctrination. The IB schools, several hundred of them, are still being added to the list. Purge - definitely! We need to formulate a plan and people need to get active in their states... know which candidates will fight this with us and vote them in!
Amazon.com Widgets


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If the Portland Trailblazers ever live up to their potential and win an NBA title, they might just owe it to the Balearic Islands of Spain. These are the islands that produced and nurtured Rudy Fernandez into a basketball juggernaut. Both his parents were professional ball players in Spain. As soon as Rudy was born, he was on the radar of every pro basketball team in the country. By the time he was 16, Rudy had a contract with Joventut Badalona and a roster spot on the Spanish national team. It was only a matter of time before NBA scouts joined the party. Fortunately for the Blazers, not very many did.
Come the 2007 NBA draft, Rudy was a hot topic. Every player ranking system you could find was touting his offensive abilities. There's no discrepancy as to why. He's a great one on one guy, gets to the rim with ease, is fluid, smooth, has amazing court awareness and is a great shooter from deep. He can play anywhere from the PG to the SF in the league. He is a leaper with above average athleticism and a quick first step second to none. So, when he dropped to the 24th pick in the draft, some eyebrows raised. Upon further inspection, it was decided that he wasn't strong enough to guard some NBA guards. It was also well-noted that in 2006, he signed a long-term contract with Joventut Badalona. The buyout in the contract was so large, he wouldn't be able to play in the NBA until the '08-'09 season. Basically, his physical strength and professional status in Spain caused him to free fall.
With the 24th pick in the 2007 draft, the Phoenix Suns took Rudy Fernandez. I wasn't the only one who saw this pick and thought it was a perfect fit. Ric Bucher of ESPN predicted that Rudy would be a perfect complement to the Suns' style of play. He thought Rudy would thrive in the league and turn out to be the "steal of the draft." Then, inexplicably, Phoenix traded Rudy along with James Jones to the Portland Trailblazers for Cash. That's right, cash. I hope that cash is enough to pay for all the therapy Suns executives are going to need when they see this guy play next year.
When Portland got Rudy for cash, they had to think, "God is a Blazer fan." Just two months after winning Oden in the lottery, they find a duffel bag full of gold bars on their front lawn. If you don't think Rudy is worth his weight in gold, go search "Rudy Fernandez" on YouTube. You'll find countless highlights, which include high-flying dunks, dribbling trickery, and unbelievable shots. What's more impressive is his game film. I've watched 5 games in their entirety and couldn't believe what I saw. The evidence is this article, which I was compelled to write based on my conclusions. Fernandez is the best player (MVP last year) in the 2nd best league in the world. He is a star in Spain and it is only a matter of time before he's a star in the NBA.
This year, in the Spanish league, Rudy is averaging 22 ppg in 28 minutes. He is also adding 4 assists, 3 rebounds, 2 steals and a block every game. He shoots 93% from the foul line and 41% from downtown. Keep in mind that this is the best player in the league, meaning teams hone in on him and he is consistently double-teamed. Over the last five years, his stats have gotten better in EVERY category listed above. In 2006-2007, he was the ACB league's MVP. He was also the 2007 FIBA European player of the year, which is given to the best European player outside the U.S. He won this award at the age of 22.
The only player I can compare Fernandez to is Gilbert Arenas. Seriously. He gets to the rim at will and has a great shooting touch. When he catches fire, which he often does, he makes absolutely everything. The only knock on him is his strength, even though he's gained 10 pounds in the last year. He is 6'6 and weighs 185 pounds. With an NBA workout regimen, he'll add another 10-15 pounds and be just fine. Defensively, he could also be special. As mentioned, he's 6'6 yet can guard the PG position. He has very quick feet, quick hands and deceptively long arms. The only thing that could keep him from being a great defender is his will. If he decides he wants to defend, he'll do it with the best of them. Physically speaking, this guy is perfect for the NBA. With these physical gifts and a jaw-dropping array of offensive skills, this guy will be an all-star. You can quote me on that. I can only hope that happens while he's in Portland.
Cheap Seats * * * Rudy Fernandez: Future NBA Star
By Chris Charbonnier ,
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Crazy for You zings with one-liners, vintage glamour, and high-energy music and dance la Fred and Ginger. With only six weeks of rehearsal, Director/Choreographer Marc Carmen whipped more than 20 dance novices into a toe-tapping sensation. Whether tap dancing on house siding, swinging on a pick ax, or creating music with a plunger, the cast leaves the audience wanting more. The lighting and clever scene changes add to the fun. Originally produced in 1992 by Ken Ludwig and Mike Ockrent, this play is loosely based on George and Ira Gershwin's 1930s Girl Crazy and is filled with classics like "I've Got Rhythm" and "Someone to Watch Over Me." Wannabe dancer Bobby Child (Denny Schaber) warms up in his character as a man trapped between his frustrated, over-the-top fiancé, Irene (Sharon Owens), and his materialistic mother (Shannon Jami Dolan). At his mother's insistence, he goes to the dead-end town of Deadrock, Nevada, to foreclose on the Gaiety Theater. Things change when he meets the owner's daughter, Polly (Katie Angell-Thomas), a cowgirl whose warm heart, strong voice, and even stronger will make him melt. She refuses him when she discovers his original intention but changes her tune when he disguises himself as the great Bela Zangler and wrangles bored locals and Zangler's Follies girls into putting on a show. A one-dimensional saloon/hotel owner, Lank Hawkins (Roger Clapp), tries to stop the production but gets distracted by a naughty Irene, who shows up unexpectedly. When Child realizes that Polly has fallen for Zangler, not him, he reveals himself; but it is not until the real Zangler (James Beecham) arrives searching for his beloved dancer, Tess (a poised Amanda Ries), that Polly believes him. Then the real comic relief begins, with winks at Charlie Chaplin, Groucho Marx, and other greats. (Through June 20 at the Lake Worth Playhouse, 713 Lake Ave., Lake Worth, 561-586-3549.) -- Rachel Galvin
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February 14, 2014 Updated Feb 14, 2014 at 5:00 PM EDT
Hunters in north India are searching for a man-eating tiger that has killed nine people.
The animal is terrorizing villagers in Maniawala, who have started traveling to work in groups and carrying homemade guns into the sugar fields. Find out more about this story by watching the video below. (Video may not display on some mobile devices)
What are your thoughts CLICK HERE to leave us a "QUESTION OF THE DAY" comment.
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Winnie Mandela (2013)
Winnie Mandela Synopsis
Starring Academy Award® winner Jennifer Hudson (Dreamgirls) and Academy Award nominee Terrence Howard (Hustle & Flow), WINNIE MANDELA is an epic story of love, sacrifice and courage. Moving from a remote tribal village to the sprawling metropolis of Johannesburg, South Africa, a proud young Winnie (Jennifer Hudson) soon found love with a rising political star, Nelson Mandela (Terrence Howard). When Nelson was imprisoned for protesting the brutal Apartheid government, Winnie worked tirelessly to win his freedom and to carry on his message of peace and equality. Her struggle to keep the Mandela dream alive was rewarded by years of persecution and imprisonment, including 18 months of solitary confinement. Throughout, her resolve to fight for her freedom, her family and her country never wavered. Her leadership and unconquerable spirit caught the attention of the world and earned her the name "the mother of the nation.
Latest 'Winnie Mandela' News
- Darrell Roodt.....Director
- Terrence Howard.....Nelson Mandela
- Jennifer Hudson.....Winnie Mandela
- Elias Koteas.....Colonel de Vries
- Wendy Crewson.....Mary Botha
- Angelique Pretorius.....Marcia
- Karl Thaning.....Ferry Policeman


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Reviews (2)Add review
Volcom Frochickie Shorts 10-26-2016
I been using Volcom frochickie shorts for our cleaning business for the past 10 years. Their great shorts that sure can take a beating.
I Have 5 Pairs 08-26-2016
I have been wearing these shorts for the past two yrs. I usually wear a size 8 in pants and I first bought these in size 11 which fit well initially, but then they stretch out a bit. I have since ordered two more pairs in size 9 which start out snug in the waist and then loosen up with wear. I can still wear both sizes but the size 11's are loose (I did loose a little weight in the past yr) and the size 9 fit snug. (I still normally wear size 8 pants). The fabric is nice and they are very comfortable. I see Volcom now has Frochickie pants in black. I hope they start offering these pants in different colors then I would probably buy as many pairs of these pants as I have shorts.


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On February 10, Binh Duong People's Committee (PC) held an opening ceremony to announce the launch of its new Public Administration Center (PAC).
On February 2, Deputy Prime Minister Nguyen Xuan Phuc visited Quang Ninh Public Administration Center (PAC) and stated that this new model should be replicated nationwide. Quang Ninh PAC is under the e-Government project implemented for Quang Ninh Province by FPT IS.
On January 26, the project to implement an "Information management system for revolutionary martyrs, martyr relatives, and martyrs' cemeteries" for the Department of National Devotees (DOND), Ministry of Labor, Invalids and Social Affairs was launched in Hanoi.
In 2015, FPT IS continues to be recognized by CyberPower and has been appointed as its exclusive maintenance partner in Vietnam.
On January 16th, 2015, the commencement ceremony for an ERP project implemented by FPT IS for United Paints Group (UPG) – the leading paint manufacturer in Myanmar – took place in Yangon, Myanmar.
On January 15, FPT IS attended the National Conference on IT Applications in the Health Industry to deliver a presentation on "FPT.eHospital – A solution recognized with ASEAN ICT Awards and successfully applied in 100 hospital across Vietnam". The conference was chaired by Vietnam Deputy Prime Minister Vu Duc Dam and Minister of Health Nguyen Thi Kim Tien.
On January 15, the Vietnam – Japan ICT Day Forum – Exhibition took place at JW Marriot Hotel, Hanoi. FPT was one of four enterprises invited to participate at this event.
On January 6, the opening ceremony for Ha Long Public Administration Center took place at No. 8A, 25/4 Street, Hong Gai commune, Ha Long city.
On January 2, the SAP ERP system implemented by FPT IS for Foundation Engineering and Underground Construction (FECON) was officially put into operation.
On January 1, FPT IS and Minh Phu Corporation announced the successful go-live of the SAP ERP system after five months of implementation. Minh Phu is the first seafood enterprise in Vietnam to apply an ERP solution.


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Police look for suspect in Wallingford store holdupNovember 29,2013PROVIDED IMAGE
Vermont State Police released this image of the suspect in the Wallingford robbery.WALLINGFORD Vermont State Police are looking for a man suspected of robbing a Cumberland Farms store in Wallingford.
Police said the man was dressed in a dark green poncho, sunglasses and a bandanna as he approached the clerk at about 11:50 p.m. Thursday at the Route 7 store and demanded money.
The man did not display a weapon, but kept his hand under the poncho, indicating he had one.
A police dog tracked the suspect behind the store, finding the bandanna and some cash on the railroad tracks.
Separately, police are looking for man who forced his way into a Circle K store on Route 12 in Weathersfield early Friday and took several items before fleeing.MORE IN This Just InPUTNEY A local women told police someone stole $400 in cash from her car. Full StoryThe Raiders had two goals in a span of about five minutes on Tuesday in upending Middlebury 2-1... Full StoryNORTH CLARENDON Often when a No. 3 seed plays a No. Full Story
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We at Midas Business Services have developed a unique 8 step process to ensure your business data is kept confidential and secure at all times.Find Out More
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Rock & Republic Call Me Blush ($40.00 for 0.32 oz.) is a gorgeous shade of shimmering pinky-coral with peach shimmer-sheen. It's really a ringer for Lancome's Mandarin Sky (which I also loved), but more-sheen-than-shimmer (and not quite as pink) NARS Orgasm. I'm obsessed. OBSESSED. with coral blushes, whether they're pink-coral, peach-coral, or orange-coral, I'm all over them.Read Full Review
Lancome Shimmer Mandarin Sky Blush
Lancome Shimmer Mandarin Sky Blush ($29.50 for 0.18 oz.) is one of the prettiest shades of coral-pink with peachy-gold shimmer and sheen. Even though it seems reminiscent of such cult favorites as NARS Orgasm and MAC Springsheen, the way the gold sheen reflects light makes it stand out. It's so wearable you could wear it as an everyday blush, but it can be worn subtly or intensely, depending on the look you're going for. It blends beautifully with skin because of the soft, smooth texture of the powder. I always forget how gorgeous this shade is until I pull it out. It's even pretty in the pan, but it's truly at its best when worn. Very glowy without being shimmery.Read Full Review