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Low Vitamin D Levels Correlate With the Proinflammatory State in Type 1 Diabetic Subjects With and Without Microvascular Complications
Epidemiologic studies link vitamin D deficiency to onset of type 1 diabetes mellitus (T1DM). T1DM exhibits increased inflammation, which is pronounced with microvascular complications (T1DM-MV). However, there are a paucity of data on vitamin D in T1DM-MV in relation to biomarkers of inflammation, and this formed the aim of the study.
Healthy control subjects (n = 36), patients with T1DM (n = 24), and patients with T1DM-MV (n =26) were recruited. Serum vitamin D levels, monocyte toll-like receptor (TLR) 2 and TLR4 expression and nuclear factor-κB (NFκB) activity were assessed.
Patients with T1DM and T1DM-MV were significantly vitamin D deficient compared with control subjects (P < .01). There was a significant negative correlation between vitamin D levels and high-sensitivity C-reactive protein, NFκB activity, and TLR4 expression (P < .05). Preincubation with vitamin D significantly decreased lipopolysaccharide-activated TLR4 expression and cytokine levels in monocytes (P < .05).
Low vitamin D levels may contribute to increased inflammation in T1DM. Future studies will elucidate the immunomodulatory effects of vitamin D in decreasing vascular risk in this population.
- Vitamin D
- Diabetes
- Inflammation
Epidemiologic studies suggest a link between vitamin D deficiency in early life and the later onset of type 1 diabetes (T1DM).1–3 T1DM is associated with an increased risk of vascular complications, and patients with T1DM with proteinuria and/or retinopathy have a significantly increased risk of fatal coronary artery disease.4 Studies have explored the relationship of vitamin D concentrations with these complications; however, many of these have not been studied in persons with diabetes.
Wang et al5 studied participants of the Framingham Offspring study (n = 1,739) who did not have cardiovascular disease at the time of enrollment. Levels of 25-hydroxyvitamin D (25-OH vitamin D) of less than 15 ng/mL (37 nmol/L) were associated with a greater risk for cardiovascular events after adjustment for cardiovascular risk factors and renal function (1.62; 95% confidence interval [CI], 1.11–2.36; P = .01). A recent meta-analysis of 18 randomized, controlled trials for vitamin D noted that intake of ordinary supplemental doses of vitamin D (300–2,000 IU) was associated with a reduced risk of mortality (relative risk, 0.93; 95% CI, 0.87–0.99).6 Chonchol and Scragg7 studied the relationships between serum levels of 25-OH vitamin D, insulin resistance, and kidney function in National Health and Nutrition Examination Survey (NHANES) III participants (n = 14,679). The level of 25-OH vitamin D was significantly lower in people with severely decreased glomerular filtration rate when compared with people with normal kidney function. In addition, people in this study with higher levels of 25-OH vitamin D had decreased insulin resistance (homeostasis model of assessment-insulin resistance). Svoren et al8 demonstrated significant vitamin D deficiency in youth (age <18 years) with type 1 diabetes, while Bierschenk et al9 demonstrated low levels of vitamin D in healthy control subjects and people with type 1 diabetes in Florida, with no significant differences between the groups.
Vitamin D has also been shown to have several immunomodulatory effects in vitro such as decreasing C-reactive protein (CRP) levels and abrogation of nuclear factor-κB (NFκB) activity, cytokines, and toll-like receptor (TLR) 4 expression.10 We and others have demonstrated that patients with T1DM exhibit increased inflammation as evidenced by increased plasma CRP levels and increased monocyte activity and increased TLR2 and TLR4 expression, and these are more pronounced in T1DM with microvascular complications (T1DM-MV).11–13 However, there are a paucity of data examining the role of vitamin D in T1DM with complications and also examining its relationship with biomarkers of inflammation, and this formed the basis of this study. Herein we report on decreased levels of vitamin D in T1DM with and without complications compared with levels in healthy control subjects.
Materials and Methods
We recruited 24 patients with T1DM and 26 with T1DM-MV (onset <20 years and receiving insulin therapy since diagnosis; present age ≥18 years; and duration of diabetes ≥1 year) from the Diabetes and Pediatric Clinics at University of California Davis Medical Center, Sacramento, and by advertisements in the local newspaper. Microvascular complications included retinopathy and nephropathy. None of the patients were receiving metformin (Glucophage, Bristol-Myers Squibb, Princeton, NJ) and/or the thiazolidinediones, angiotensin-converting enzyme inhibitors, angiotensin receptor blockers, or statins, as described previously.11 Other exclusion criteria were as follows: mean glycated hemoglobin (HbA1c) during the last year more than 10%; inflammatory disorders, eg, rheumatoid arthritis; macrovascular complications such as stroke or myocardial infarction, abnormal liver, renal, or thyroid function; malabsorption; steroid therapy; smoking, abnormal CBC, and alcohol consumption of more than 1 oz/d; consumption of fish oil capsules (>1 g/d); and "chronic" high-intensity exercisers.
Healthy control subjects (n = 36), older than 18 years, were included if they had a normal CBC; no family history of diabetes or other chronic diseases; normal kidney, liver, and thyroid function; and a fasting plasma glucose level less than 100 mg/dL (5.6 mmol/L). Healthy control subjects and patients with T1DM and T1DM-MV were matched for age (within 10 years), sex, and race. Exclusion criteria were as described previously.11 Informed consent was obtained from participants in the study, which was approved by the institutional review board at the University of California Davis. After a history and physical examination, fasting blood samples (30 mL) were obtained.
High-sensitivity (hs) CRP levels in serum were assayed using the Beckman LxPro autoanalyzer (Beckman Coulter, Brea, CA). Total calcium and phosphate levels were also assessed in the clinical laboratory. Vitamin D levels were measured using the LIAISON 25-OH Vitamin D TOTAL assay (DiaSorin, Saluggia, Italy), which is an antibody-based vitamin D chemiluminescent assay that measures total 25-OH vitamin D, including D2 and D3 metabolites. Interassay and intra-assay coefficients of variation of the vitamin D assay were less than 8.5%.
Mononuclear cells were isolated from fasting heparinized blood by Ficoll Hypaque centrifugation, followed by magnetic separation of monocytes using the depletion technique (Miltenyi Biotech, Auburn, CA), as described previously.11 NFκB p65 activity was examined and expressed per milligram of cell protein, as described previously.11–13 TLR2 and TLR4 expression was examined by flow cytometry, as described previously.13
To examine the relationship between vitamin D and TLRs, we incubated monocytes with 1,25-dihydroxyvitamin D3 (0.1 μmol/L) for 24 hours and then activated the cells with lipopolysaccharide (LPS; 100 ng/mL) and examined TLR4 expression by flow cytometry and cytokine analyses by multiplex array.
Statistical analyses were performed using SAS software (SAS Institute, Cary, NC). Data are expressed as mean ± SD for parametric data and as median and interquartile range for nonparametric data. Following analyses of variance, parametric data were analyzed using paired, 2-tailed t tests and nonparametric data using Wilcoxon signed rank tests. The level of significance was set at a P value less than .05. The Spearman rank correlation was computed to assess association between variables.
Baseline subject characteristics are given in Table 1. There were no significant differences in age, body mass index, and male/female ratio in the control, T1DM, and T1DM-MV groups. In addition, there were no significant differences in the lipid profile, including low- and high-density lipoprotein cholesterol (data not shown). As expected, levels of glucose and HbA1c were significantly higher in the T1DM and T1DM-MV groups compared with the control group. Also, levels of hs-CRP were significantly increased in the T1DM and T1DM-MV groups compared with the control group, and this was more pronounced in the T1DM-MV group as reported previously11 (Table 1).
Monocyte surface expression of TLR2 and TLR4 was significantly up-regulated in the T1DM-MV group compared with the T1DM and control groups, as reported previously13 (Table 1). Furthermore, downstream signaling of TLR, ie, NFκB activity, was significantly increased in resting monocytes from the T1DM-MV group compared with T1DM and control groups (P < .005).13
The novel data we report here are the levels of vitamin D in T1DM with and without microvascular complications compared with control subjects. As shown in Figure 1, patients with T1DM and T1DM with complications were significantly vitamin D deficient compared with healthy control subjects (P < .01). Although decreased compared with the control group, the levels of vitamin D were not significantly decreased in the T1DM-MV group compared with the T1DM group. While 17% (6/36) of control subjects were also deficient and had values less than 20 ng/mL (50 nmol/L), 29% (7/24) and 35% (9/26) of the T1DM and T1DM-MV groups, respectively, had vitamin D values less than 20 ng/mL (50 nmol/L). There were no significant changes in total calcium or phosphate levels in patients with T1DM compared with control subjects (data not shown).
Because vitamin D seems to have immunomodulatory activity and T1DM has been shown to be a proinflammatory state, we examined correlations between low vitamin D levels and increased biomarkers of inflammation in T1DM, ie, hs-CRP, mononuclear NFκB, and monocyte TLR expression. As shown in Table 2, there was a significant negative correlation between vitamin D levels and hs-CRP (r = −0.67; P < .01); NFκB activity (r = −0.49; P < .05); and TLR4 expression (r = −0.37; P < .05); there was no significant correlation with TLR2 expression.
To examine the relationship between vitamin D and TLRs, we incubated monocytes with 1,25-dihydroxyvitamin D3 (0.1 μmol/L) for 24 hours and then activated cells with LPS and examined TLR4 expression and cytokine release. As shown in Table 3, preincubation with vitamin D significantly decreased LPS-activated TLR4 expression and cytokine levels in these monocytes (P < .05).
T1DM is associated with increased microvascular complications. Inflammation has a crucial role in vascular complications. T1DM is a proinflammatory state characterized by increased levels of circulating biomarkers of inflammation such as hs-CRP. We have previously shown increased systemic and cellular inflammation in T1DM-MV compared with T1DM11–13 as evidenced by increased hs-CRP, increased monocyte cytokines, increased monocytic expression of TLR2 and TLR4, and their downstream signaling such as increased NFκB activity. Several lines of evidence from epidemiologic studies and in vitro studies indicate that T1DM is associated with decreased vitamin D levels7–9 and that low vitamin D levels may contribute to increased risk of microvascular and macrovascular complications. However, there are no studies examining the vitamin D level in T1DM-MV compared with age- and sex-matched T1DM cases and its contribution to the accentuated proinflammatory state of T1DM. In this report, we provide novel data on significantly decreased levels of vitamin D in T1DM compared with control subjects and significant negative associations with biomarkers of inflammation such as hs-CRP, NFκB activity, and TLR4 expression.
While the relationship of vitamin D to complications has not been studied in T1DM, this association has been studied in nondiabetic subjects and reported. In the Framingham Offspring study,5 participants did not have cardiovascular disease at the time of enrollment. At baseline, the mean 25-OH vitamin D level was 19.7 ng/mL (49 nmol/L), and 37% of persons had levels less than 15 ng/mL. At a mean follow-up of 5.4 years, 120 participants had experienced a cardiovascular event. Levels of 25-OH vitamin D of less than 15 ng/mL (37 nmol/L) were associated with a greater risk for cardiovascular events after adjustment for age and sex, other cardiovascular risk factors, and renal function (relative risk, 1.62; 95% CI, 1.11–2.36; P = .01). When models were created to examine the following categories of vitamin D concentrations (≥15, 10–15, and <10 ng/mL [37, 25–37, and 25 nmol/L]), the hazards ratio demonstrated a linear trend (1.00, 1.53, and 1.80, P = .01) for increased cardiovascular risk. The authors suggested that correction of the vitamin D deficiency might be important for the prevention of cardiovascular disease. A recent meta-analysis of 18 randomized, controlled trials for vitamin D noted that intake of ordinary supplemental doses of vitamin D (300–2,000 IU) was associated with a reduced risk of mortality (relative risk, 0.93; 95% CI, 0.87–0.99).6 In the NHANES III cohort,7 the level of 25-OH vitamin D was significantly lower in people with a severely decreased glomerular filtration rate compared with people with normal kidney function. All of the aforementioned studies indicate that low vitamin D levels are associated with increased cardiovascular risk.
In the present study, we showed significantly decreased levels of vitamin D in T1DM with and without microvascular complications. However, despite lower values in T1DM-MV, these were not significantly lower compared with T1DM, and this relationship needs to be confirmed in larger studies. Previously, European studies have reported decreased 25-OH vitamin D and 1,25-dihydroxyvitamin D3 in patients with newly diagnosed T1DM and in type 2 diabetes mellitus.1,2,6 A recent study failed to show the association of decreased vitamin D in patients with T1DM in Florida; however, despite the sun-rich environment, all subjects, including healthy control subjects, were vitamin D insufficient, confounding analyses of differences between control subjects and patients with T1DM.9
Vitamin D has been reported to be immunomodulatory.10 In this study, we report in T1DM cases a significant negative association between vitamin D levels and hs-CRP, TLR4 expression, and NFκB activity. Previously, negative correlations between hs-CRP and 25-OH vitamin D levels have been reported in some studies of kidney transplant and obese subjects.14 Also, 1,25-dihydroxyvitamin D3 in vitro has been shown to decrease LPS-induced cytokine release and NFκB activity from monocytes.15,16 In addition, in monocytes, vitamin D treatment (1,25-dihydroxyvitamin D3) significantly reduces the response/immune activation of cells in response to TLR2 and TLR4 agonists.17 Since T1DM and T1DM-MV have increased monocyte TLR2 and TLR4 expression and increased NFκB activity, we examined relationships with low vitamin D status. The significant negative correlation between vitamin D levels and biomarkers of inflammation shown in this study indicate that low vitamin D levels may contribute to the increased inflammation in T1DM. These data are supported by our in vitro studies on the efficacy of vitamin D in decreasing TLR4 and cytokine release from monocytes. Future studies will provide mechanistic insights into this association, and clinical trials using vitamin D in T1DM will be important to elucidate the immunomodulatory effects of vitamin D in decreasing vascular risk in this population.
Upon completion of this activity you will be able to:
list findings that provide evidence that type 1 diabetes is a proinflammatory state.
understand vitamin D levels in type 1 diabetes.
list specific immunomodulatory actions of vitamin D.
The ASCP is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians. The ASCP designates this educational activity for a maximum of 1 AMA PRA Category 1 Credit ™ per article. This activity qualifies as an American Board of Pathology Maintenance of Certification Part II Self-Assessment Module.
The authors of this article and the planning committee members and staff have no relevant financial relationships with commercial interests to disclose.
Questions appear on p 478. Exam is located at www.ascp.org/ajcpcme.
We thank Manpreet Kaur for technical assistance.
Supported by grants K24AT00596 and DK69801 from the National Institutes of Health, Bethesda, MD.
- © American Society for Clinical Pathology


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Emergency Physician
34 years of experience
34 years of experience
9540 Garland Rd
Dallas, TX 75218 Phone number & directions
Dallas, TX 75218 Phone number & directions
License & Identifications
A medical license is required for a doctor to practice medicine in a particular state. Requirements vary by state but most require, at a minimum, post-graduate training in the doctor's specific specialty. An NPI number is a national identifier unique to an individual health care provider and is managed by the Center for Medicare & Medicaid Services (CMS).
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Dr. Gregory Byrne, MD is board certified in Emergency Medicine.
Education & Awards
Dr. Byrne graduated from University of Mississippi , Jackson.
Dr. Byrne has 37 hospital affiliations:
- Harris Methodist H E B
- Baylor Regional Medical Center At Grapevine
- Spanish
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- Dr. Gregory J Byrne MD is a male Emergency Medicine Specialist, has 34 years of experience and practices in Emergency Medicine.
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Dr. Gregory Byrne practices Emergency Medicine near Dallas, TX.
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subset: commoncrawl


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STONEY POINT - A suspected drug dealer from Rockland County is off the streets this morning.
Police say David Garrison, 20, of Stony Point, was arrested over the weekend after investigators found a stash of ecstasy, marijuana and other drug paraphernalia inside his home.
Police say they started their investigation into Garrison after getting complaints from neighbors who witnessed the alleged deals go down.
Bail was set at $3,000 and a court date was scheduled for April 15.


text: Located in a quiet area in Rimini, Hotel Tiffany features a large outdoor pool and air-conditioned rooms with a balcony. The beach is 1,477 feet away and provides organised entertainment for children and adults. Free bikes are available. The elegant rooms feature wooden furniture and marble floors. They feature a flat-screen TV and a digital safe. The air-conditioned rooms at Hotel Tiffany have large soundproofed windows. The Tiffany's swimming pool is surrounded by sun loungers and parasols. Additional facilities include a solarium, a large reception lounge with a 24-hour front desk, free WiFi throughout and comfortable dining spots. A complimentary buffet breakfast is served every day. Regional and national delicacies are served in the onsite restaurant. Alternatively, the surrounding area offers several restaurants and pizzerias. Rimini Train Station is 1.2 miles away. The Republic of San Marino is just 14.3 miles away. The Casentinesi National Woodlands Park is 62.8 miles away.


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Chris Rock reveals how powerful Adam Sandler really is in Hollywood
Chris Rock isn't just talented, he's damn smart. You don't go from stand up to your own HBO special to hit movies ("Down to Earth," "The Longest Yard") to hosting the Oscars to producing critically acclaimed TV shows ("Everybody Hates Chris") on just making people laugh. The 45-year-old quadruple threat (if not more) shepherded "Death of a Funeral," an American remake of Frank Oz's British comedy from a few years ago that opens in theaters today and you can argue it was his creative input that convinced Screen Gems to jump on board.
Speaking to Rock is always fun because even after all his time in the industry his candid personality has hardly softened. You don't get any publicity talking points with Rock. So, chatting about "Funeral," this writer found it intriguing that Rock didn't direct the film himself after his impressive debut "I Think I Love My Wife." In fact, many fans and a good number of his peers (including Quentin Tarantino it seems) have been wondering when Rock will step behind the camera again. Rock insists that he will bring his voice to the director's chair soon, but felt he couldn't handle the visuals for "Funeral's" contained story which takes place almost completely within one big house (his "Nurse Betty" director Neil LaBute came on board instead). Again, you can't fault Rock for being honest.
Most intriguing, however, was Rock riffing on how quickly his old "Saturday Night Live" buddy Adam Sandler can get a movie made. It's no secret that Sandler has been the gold mine at Sony Pictures for the better part of a decade and has semi-free reign with the studio's management. So, when one picture fell apart a few years ago, Sandler and his producing partner literally pulled a remake of "The Last Yard" out of their backpockets and got it greenlit in three weeks (that's not a misprint). That's real power people and no one was complaining when it made $158 million the following year (except critics of course). Rock and Sandler reunite onscreen in "Grown Ups" later this summer.
You can view this candid conversation with Rock embedded within this page or for a larger version, click here.
"Death at a Funeral" is now playing nationwide.


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Cyberbullying, Fat-Shaming, and Homophobia on Hamptons "Douche Spotter"
The New York Post had a promising story this morning about a Facebook group created by East Hampton locals dedicated to calling out the douchey behavior of the elitest weekenders invading their hometown.
"Facebook page nails Hamptons D-bags for their bad behavior and maddening antics" the headline blared. This is going to be good, we thought, rubbing our hands together in anticipation. (The Today show thought so too--hosts chatted about the Facebook group on the air this morning.)
Outrageous stories of "citidiots" running amok in the Hamptons are some of our favorites. Take the Twitter account @HamptonsBorn, for instance--where East Hampton local and self-described "house watcher" Joe Schwenk catalogs the bizarre requests he fields on a daily basis (ex: "Drive a poodle back to NYC while owners catch a copter ride w/rich friends"). Love it!
But if you were looking for an equally amusing glimpse into life as a Hampton local you'll be disappointed by "Douche spotter." The Facebook group at the center of the Post's story is half cyber-bullying forum, half creep-shot repository--with several dozen photos of legitimately frustrating parking jobs sprinkled in for good measure.
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It's hard to tell in most cases what the person pictured did to deserve the brand "douche"--some are ridiculed for having sock tan-lines, others for wearing socks with sandals, and, in one case, for using a motorized scooter. A photo of an old lady walking down the street in the rain is captioned "nice wig douche."
Photos of overweight folks (at the beach, walking down the street, waiting be served at a deli counter) invoke snickering comments. "Break me off a piece of that!" one wrote about the lady at a deli counter. "That was just gross that day...lol," read the caption of the man at the beach. "Back breasts!" howled one person who posted a photo of a heavyset woman's back.
There's some good old-fashioned homophobia, too! "You know your in the hamptons when you see two faggots riding a tandem bike to the beach," wrote one member who posted a cell phone shot of two men on a bike. Another photograph of two men sitting side-by-side carries the comments, "How does he have a gf when he looks like a flammer?!" and "He looks like a fudge packer hahaha fuck this ppl."
Really, New York Post? Really, Today? This is what we're celebrating?
Even members of the group (there were close to 1,000 of them when the Post's story went live, but that number had almost tripled a few hours later) are starting to complain--not that the page's administrator has any time for that.
"This isnt for sensitive, dramatic little crybabies and everybody is free to express themselves so be gone if you cant handle it," James Cuomo wrote on Monday. On Wednesday he added: "This site was to have fun pointing out assholes that think they are better than everyone and can do what they want if you have a problem with it then leave nobody wants to hear you complain."
So, who are the douchebags--the people in the pictures, or the people snapping the photographs surreptitiously from a distance, then posting them on the Internet? Decide for yourself: Facebook.com/groups/douchespotter.
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text: Memorable Movie Mondays – 100 Greatest Movie Threats of All Time By Craig G August 16, 2011 Video courtesy of YouTube/hh1edits Great compilation of the greatest threats. Especially enjoyed the Nicholas Cage one. Hit the green box to the top left of the post to leave a comment. Share this:TwitterFacebookGooglePinterestLike this:Like Loading... Related


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Semi Flush Ceiling Light - P591
from George Kovacs
free shipping on most orders
George Kovacs
The first George Kovacs lamp store opened in Manhattan in 1954 and has since evolved into a lighting collection featuring a broad range of high-quality lighting fixtures produced with a mid-century modern flair.
A team of renowned designers, including George Kovacs himself, Karim Rashid, Alecia Wesner and Rachel Simon, have designed a wide selection of wall sconces, pendants, ceiling lights, bath lighting and table and floor lamps, sure to fit in to any modern decor.
Rated 5 out of 5 by Paulette from Well-made fixture, nice simple design. I wanted something different for my kitchen and this is perfect. It gives plenty of light and the finish matches my cabinet pulls.
Date published: 2014-07-03
Rated 5 out of 5 by Anonymous from Exactly as pictured This is a great light to give any room a more industrial feel. We used it in our laundry room and it is exactly what we expected
Date published: 2013-12-20
Rated 5 out of 5 by Anonymous from Disappointed. The fixture looks more interesting in the picture. We chose the bronze one and found the design simple but the installation a little cumbersome. We expected it to be more substantial and will repla e it when we find something more interesting for our kitchen.
Date published: 2013-01-28
Rated 5 out of 5 by Anonymous from Exacty What We Were Looking For The light is exactly what we were looking for. It's modern looking and gives a lot of light to a large room.
Date published: 2012-12-17
Rated 4 out of 5 by Eric P. from Exactly what I wanted The lamp was exactly what I was looking for. Easy to put together, matched the lamp in the living room, contemporary and incandescent. Bought a dimmer and the lighting was perfect. Hard to beat the incandescents for warmth.
Date published: 2012-12-26
Rated 4 out of 5 by Debbie R. from It is exactly what I wanted. The fixture is made very well, easy to install and a very nice design.
Date published: 2012-09-24
Rated 4 out of 5 by Anonymous from Excellent product, easy installation. We are very happy with this product-- the electrician had no trouble installing it, it provides an excellent amount of light, and looks even better in person than it did online. Totally happy with this purchase.
Date published: 2012-03-26
Semi Flush Ceiling Light - P591 is rated out of 5 by 7.


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Daffodil (Shui Hsien) is one of the oldest traditional Wu Yi Oolong teas. It has all the features of Wu Yi Rock Teas including: dark and rich brownish red color of the dry leaves, roasted flavor and clear deep yellow to reddish tea liquid. The emphasis of Daffodil compared to other Wu Yi teas is that it is lighter and has more flower or fruit like aroma and taste.
Quality & Package Size: We offer one quality grade and one packaging size (50gms) currently for Daffodil Oolong tea.
Shipping: We ship using Australia Post and advise quotes and expected delivery times with each purchase . This is obtained directly from Australia Post's web site during the final stages of the purchase-checkout process and based on total weight of the package in the cart. Free shipping for orders that have exceeded $80 AUD within Australia.
Rich taste with traces of honey and a slightly burnt flavour.


text: Hey Guys- In looking for ways to store some of the ammo I'm building up I got to thinking....... Why not buy one of the cheapy metal gun cabinets at Dicks or Walmart and install a golden rod in it, put a seal on the door and install shelves to store ammo on? What do you think? I think it would be fairly thick gauge metal, decent lock, and should keep ammo consitant temps and dry....everything an ammo can does but more organized than a bunch of cans under the bench. Just gathering ideas and opinions. Thanks Josh


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The Gateway Hotel
Built on the concept of a palace, the hotel's design bears a true testimony to the architectural heritage of Jodhpur. The hotel's rooms are an intricate blend of contemporary and traditional styles and offer pool, garden or a courtyard view. The hotel is an epitome of traditional heritage and luxury, offering an unforgettable experience to its guests.
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Services and terms: The Gateway Hotel
Standard Room Services
- Air Conditioning
- Minibar
- Hairdryer
- Television
Accommodation facilities
- Lift
- Bar/Café
- Business Centre
- Money Exchange
- Meetings Room
- Nursery
- Internet Centre
- Garden/Terrace
- Laundry
- Non-smoker Rooms
- Parking
- Hairdresser
- Restaurant
- 24 hr Room Service
- Shops
Leisure facilities
- Billiards
- Gym
- Games Room
- Massage
- Swimming Pool
Useful information: The Gateway Hotel
Other names for The Gateway Hotel:
The Ummed
Jodhpur The Gateway
Location: The Gateway Hotel
Nestled in landscaped gardens, the hotel is located in the heart of the city. It offers a perfect setting to experience the rich culture and tradition of Rajasthan. The Jodhpur Palace, Umaid Bhawan Palace and the Mehenrangarh Fort are some of the major sightseeing places near the hotel. The hotel can be easily accessed from Jodhpur Airport.


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Miami made 11 of 19 field-goal attempts in the third, outscoring the Nets 29-15 and outrebounding them 14-7. The Nets had 19 turnovers overall, which Miami (4-1) cashed into 31 points, and made just 3 of 21 attempts from three-point range, nailing a total of only 30 of 80 shots from the floor. "This team shouldn't be losing by 30 to anybody," Deron Williams said. "But it's a work in progress. We can all play better. I can definitely play better and take care of the ball better. We can all play better defensively and we all know that. It's still early in the season. We're 1-2.
Nets Follow Ugly Loss to T-Wolves with Drubbing from Heat
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On 25th April, Nepal was struck by a 7.8 magnitude earthquake, the strongest shock in 80 years. The earthquake destroyed homes, public buildings and roads, taking the lives of over 8700 people and affecting the livelihoods of over 8 million people; almost a third of the country's population. A 7.1 magnitude earthquake shook Nepal again [more…]
On Wednesday 17th June, in the bright sunshine, The Humanitarian hosted its annual Garden Party at the Millpond, Cambridge, nestled into a backdrop of the River Cam. After a long year, the event provided a welcoming setting for volunteers and organisations, past and present to meet, discuss and have a good old chinwag about their [more…]
The Humanitarian Centre was pleased to deliver another great networking event for the development community at the beginning of June. It was a lively and vibrant evening with some highly engaging conversation. Most importantly however, some very worthwhile and professional connections were created, hopefully proving fruitful in the near future. Set in Hughes Hall, [more…]
As a way to continue engagement with our previous theme year, Food Security, The Humanitarian Centre facilitated a seminar presenting issues surrounding the subject. 'Assuring food security to 2050' seminar, jointly conceived by The Tropical Agriculture Association (TAA) and the Humanitarian Centre in collaboration with CambPlant, Cambridge Conservation Forum (CCF) and the University's Global [more…]
As part of the Cambridge Science Festival, the Humanitarian Centre hosted a panel discussion with the Cambridge Forum for Sustainability and the Environment on the question "Do we have a right to sustainable development?". We were lucky to have three distinguished speakers: Professor Carolyn Stephens, Dr Catherine MacKenzie, and Professor Peter Guthrie. Professor Stephens connected [more…]
The Humanitarian Centre is constantly working to explore areas of interest to international development, and over the years these have taken many forms, including looking at food security and health. This year we are looking at Empowering Voices and Human Rights, and in the recent event on "Justice within reach – how the law can empower", [more…]
The Humanitarian Centre has been working for a number of years on facilitating innovative international development by building effective partnerships between the members of our network in Cambridge and the developing world. This year we are drawing attention to the importance of working directly with people and communities in developing countries and prioritising their goals [more…]
I-Teams in collaboration with the Humanitarian Centre, will be launching an exciting new programme – Development i-Teams – for the first time in Easter Term 2015. The programme will run on Thursday evenings at the IfM, from May 14th to June 11th. Teams will investigate how to maximise the impact of new technologies in the [more…]
By Millie Cherfils New report and awareness-raising feast bring local focus to global poverty Between the soup course and the main dish of rice and vegetables, dozens of people who gathered for a feast heard about hunger months in South Sudan and the plight of banana farmers striving to earn a living wage [more…]


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Which Joe gave his name to 'sloppy joes'? We look at five interesting sandwiches and their lexical origins.
Definition of Armenian Church in English:
Armenian Church
(also Armenian Apostolic Orthodox Church)
proper noun
An independent Christian Church established in Armenia since c.300 and influenced by Roman and Byzantine as well as Syrian traditions. A small Armenian Catholic Church also exists (see Uniate)→ Uniate
Further reading
You have been warned: the debate on trigger warningsRead more
Are you looking for a word for a foolish person? We explore twelve interesting words to describe the dunderheads in your life.
6 'run' phrases you probably don't knowRead more
Before you run for the hills, let's run through a list of 'run' expressions that are running through our minds.
How brothers became buddies and brosRead more
The definitions of 'buddy' and 'bro' in the OED have recently been revised. We explore their history and increase in popularity.


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Follow HitFix Follow @hitfix
Firewall & Iceberg Podcast, episode 154: 'American Horror Story,' 'Suburgatory,' 'Hunted' & more
Dan and Alan also review 'Emily Owens, M.D.,' 'Underemployed' and 'The Girl'
It's a very late in the day installment of the Firewall & Iceberg Podcast, as Dan and I talk about shows returning and new, discuss the season's first cancellations and some other moves of note, and continue what's for now been a weekly "Homeland" segment.
The line-up:
"Emily Owens MD" (00:01:00 - 00:08:15)
"Underemployed" (00:08:20 - 00:16:15)
"Suburgatory" (00:16:15 - 00:23:45)
"American Horror Story" (00:23:50 - 00:32:20)
"Hunted" (00:32:25 - 00:44:15)
"The Girl" (00:44:20 - 00:54:40)
Early cancellations (00:54:40 - 01:05:20)
"X Factor" Hosts (01:05:25 - 01:10:35)
"Homeland" (01:10:40 - 01:23:30)
As always, you can subscribe to The Firewall & Iceberg Podcast over at the iTunes Store, where you can also rate us and comment on us. Or you can always follow our RSS Feed, download the MP3 file or stream it on Dan's blog.


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One of Kentucky's main quarterback targets in the Class of 2005 has put thoughts of recruiting on the back burner for the time being.
Recruiting focus on hold for Stull
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Raising the Flag Again
Police officers hope to see more United States flags throughout Arizona and the country.
Police officers hope to see more United States flags throughout Arizona and the country.
Rodders Days brings car lovers together
Sean Prentiss' book explores the complicated legacy of Edward Abbey, and follows his footsteps through the Sonoran Desert region.
Learn about the importance of blood donations from both sides of the story.
Meet fifteen-year old Mike and his Big Brother Elliot, a friendship that started with help from a non-profit organization.
Tucson Audubon Society's New Executive Director
Atypical exercise class is part of an international movement.
Did you know that every year, "Happy 100th Birthday" cards are being sold in larger numbers? Meet and hear stories from women and men aged 99 years and older.
SAGA works on advocacy, awareness and services.
Diverse UA film showcase includes a contemporary silent film about the trumph of a dancer's spirit, and a horror / comedy / musical about the wife of a serial killer.
The Arizona State Schools for the Deaf and the Blind stages an ambitious production of Disney's "Beauty and the Beast" with singing, dancing, and signing.
What do citizens who have immigrated to Arizona from Nigeria have to say about life in the U.S.? Attend a community meeting for buiding friendship and support.
The event's 3rd year helped more than two hundred teens attend prom
Astronaut Scott will soon start one year in space; scientists will compare him with earthbound twin Mark.
People with Parkinson's disease find physical and emotional benefits with exercise.
Imagine learning to read and write after more than fifty years of keeping your illiteracy a secret. Uwe Keilitz shares how he became a reader and teacher after turning his life around.
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Cash could aid Linux migration tool
Novell is likely to use its windfall to develop Mono and other open source products, said Butler Group senior research director...
This Article Covers
Risk management
Your exclusive guide to CIO trends
A collection of our most popular articles for IT leaders from the first few months of 2016, including: - Corporate giants recruit digitally-minded outsiders to drive transformation - Analytics platforms to drive strategy in 2016 - Next generation: The changing role of IT leaders.
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Available since June, Mono version 1.0 provides developer tools and the infrastructure needed to run .net client and server applications. It includes a compiler for Microsoft's C# language, a runtime engine which Mono developers said supports Microsoft's Common Language Runtime and .net libraries including ADO.net and ASP.net.
Blowers said users would find Mono worth looking at but he warned, "It is early days, so proceed with caution."
Forrester analyst Uttam Narsu said Mono was not yet a mature enough to develop and support Microsoft applications on Novell's Linux platform.
He said that many users are concerned that Novell might unwittingly infringe Microsoft's intellectual property rights during Novell's development of Mono.
Novell said any possible patent infringement could be addressed by redesigning Mono to avoid infringement or pursuing a licence with the patent owner.
Enjoy the benefits of CW+ membership, learn more and join.
Reinventing Bahrain's Kanoo Group through digital technology
Read more on IT risk management
Security Think Tank: Five tips for creating a patch management strategy
Security Think Tank: Security patching an essential element of outsourcing contracts
Security Think Tank: Allocate maintenance processes to each piece of key software
Security Think Tank: Using vulnerability management to support the patching process
Lancaster and Newcastle researchers tackle Met Police email challenge
InfoSec Europe 2012: A look at IT security skills in the current climate
Tim Wilson, deputy head of ICT at NHS City & Hackney, on ISO 27000 compliance
Input from the business vital to risk management in infosec, says CISO for Steria UK


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Futura 144 or 2010 Go 133?
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14th March 2012, 09:56 AM
Join Date: Apr 2009
Location: Montréal (PQ) CANADA
Posts: 245
as i am also a heavyweight @ 100 kilos/220 pounds, and sail in lighter winds - like 10 to 15 mph, i suggest a bigger floatier board like a 145 or even a 160 liter board. Now i use a racier longboard in 10 knots and love it more than the 160 liter board - goes better through the lulls when using a cambered freerace sail. People tell me the Futura is much better board in terms of performance than the GO - in the end, you choose
joe windsurfer
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Individuals with Metabolic Syndrome and high hostility levels have a four-fold risk of having a heart attack compared to those without these cardiovascular risk factors, according to researchers.
While evidence suggests that the Metabolic Syndrome and hostility are independent risk factors for the development of heart disease, the combined effect of these two factors on the incidence of myocardial infarction (MI) has rarely been studied.
Dr. John F. Todaro, of Brown Medical School in Providence, Rhode Island prospectively examined the effect of having both Metabolic Syndrome and hostility on the frequency of heart attacks in 754 men (average age 59 years) who participated in the Normative Aging Study. At baseline, the subjects were free of heart disease and diabetes. 27% met the criteria for having Metabolic Syndrome. The subjects were categorized as having high or low hostility levels.
The subjects were followed for an average of 13.8 years. Subjects with high hostility levels and the Metabolic Syndrome had a more than 4 times greater risk of having a heart attack.
"Psychological factors need to be assessed by primary care doctors and cardiologists, since hostility and other negative emotions (e.g. depression) seem to play a role in the development of heart disease in otherwise healthy individuals," Dr. Todaro said in an interview. "Individuals who notice that they experience feelings of anger and hostility often, should mention these feelings to their doctor and seek help… We need to better understand how hostility influences the development of CHD," he said. "Is it through physiologic mechanisms, behavioral mechanisms, or both?"
As Metabolic Syndrome, heart disease, and hostility associated with depression can both be caused by a low testosterone level in men, this factor should be looked for and treated in any man with these medical problems, as it is easily treated with bioidentical natural testosterone. To find a physician trained in this area (they will usually be holistic) visit the Fibromyalgia and Fatigue Centers.
The results of the study are published in the July 2005 issue of the American Journal of Cardiology.
For more information, see the following:
Walking Away From Metabolic Syndrome and Heart Attacks
Coenzyme Q10 Beneficial in Metabolic Syndrome
Low Vitamin D Associated with Metabolic Syndrome and Diabetes


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After billions of dollars spent, the impact on student achievement of computer use in K12 has been essentially zero. The reason is: The same textbooks, the same curriculum and the same pedagogy continue to be used, but computers have been substituted for pencil and paper. Teachers have had their students use computers to search for information instead of having them go to their school library. Direct instruction is the technical term for this teacher-centric pedagogical style, but we refer to it as "I teach."
In tough economic times for school districts across the nation, might it help to cut costs further if districts required students to bring their own devices? For now the jury is out, but district leaders are trying to figure out how to support many different devices in their buildings as state and federal funds for education get even tighter than they were just a few years ago.
In 2008 for the first time, laptops outsold desktops. In 2010 for the first time, smartphones outsold laptops.
Mobile learning is on the rise, and consequently, so is the need for mobile connectivity. According to a 2010 survey of E-rate consumers, including public schools and libraries, conducted by the Federal Communications Commission (FCC), 50 percent of respondents said they plan to implement or expand the use of digital textbooks and other wireless devices.
According to a recent study, 43 percent of students feel unprepared to use technology in college and work life. SOURCE: e Education Development Center and Nellie Mae Education Foundation
Everything was hunky-dory. Baby-boomer-age teachers prepared baby-boomer children to take on baby-boomer- age jobs. But things have changed. In the 1990s, the baby-boomer jobs started drying up, and the baby-boomer kids became the digital generation, playing video games and listening to illicit MP3s. And now? Well, it's not hunky-dory at all. Baby-boomer teachers are preparing the mobile generation.
In your schools, In your classrooms, you will soon allow students to use computing devices they already own. While today 99 percent of schools ban cell phones and other mobile devices from the classroom, there will be a 180-degree turnaround within four years. This coming shift is inevitable.
Elliot: It looks like mobile learning is finally at its tipping point.
Cathie: It really depends on one's definition of mobile learning. Schools are buying carts of iPads.
Elliot: I know, it breaks my heart. Haven't we learned anything from the past?
Cathie: A cart of iPads will have about as much impact on student achievement?
Elliot: ...as a cart of laptops had on student achievement. Deja vu all over again!
Cathie: And lest there be any doubt about what we mean...
Mobile learning—the use of mobile devices for educational purposes by students—is rapidly moving from an experimental initiative by a few innovative districts over the last five years to a broadly accepted concept in K12. The latest research and surveys, results of pilot programs, and analysis of trends in both public education and the broader technology industry all indicate that ubiquitous mobile learning—with mobile devices in every student's hands and used in every classroom, school and district in the country—is advancing quickly and will arrive faster than many expected.


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Cossons to visit Independence Hall
WHEELING – Sir Neil Cossons, former English Heritage chair and Ironbridge Gorge Museum and Greenwich National Maritime Museum director, will give the presentation "A Future for the Past: Preserving the Past as an Asset for the Future" at 7 p.m. May 9 at West Virginia Independence Hall.
He is pro-provost and chair of the Council of the Royal College of Art in London.
Cossons will discuss the philosophy and processes for historic preservation in England and other countries. He will examine what is preserved, why and how; consider new uses for historic buildings; discuss common challenges and how communities can use historic places as the framework for creating the future.
He was knighted in 1994 for his work with museums and historic preservation and has advised governments, museums and preservation organizations in several countries.
The Ironbridge Gorge Museum is a World Heritage site in Shropshire encompassing 10 museums collectively telling the story of the Industrial Revolution. English Heritage is the oversight body responsible for the management of the historic environment of England. Each year the organization opens more than 400 properties to 5.5 million visitors and cares for the National Heritage Collection of historic sites and monuments while serving as guardian of more than 500,000 objects and 12 million photographs in their public archives.
For information, call the West Virginia Humanities Council at (304) 346-8500.


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Dynamic Plaques - FVT Plaques
FVT Plaques is introducing new dynamic plaques to recognize police and sheriff's...
sponsored by
Roger Rodriguez
Manager of Image Analytics
Roger served over 20 years with the NYPD, where he spearheaded the NYPD's first dedicated facial recognition unit. The unit has conducted more than 8,500 facial recognition investigations, with over 3,000 possible matches and approximately 2,000 arrests. Roger's enhancement techniques are now recognized worldwide and have changed law enforcement's approach to the utilization of facial recognition technology.
A staple section of local newspapers has always been the short crime report items culled from the police blotter. Usually, it's a cub reporter's first job to head to the local substation to jot down pertinent details from the crime reports officers take about mostly petty crimes. Once in awhile, these young reporters submit a suggestion for a headline that squeaks by an overworked, bleary eyed editor. Sometimes, as they say, mistakes were made.


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With a stay at Hotel La Posada del Angel in San Salvador, you'll be in a shopping district and minutes from Plaza Futura and close to Estadio Cuscatlan. This hotel is within close proximity of Centro Comercial Galerias and Museo de Arte de El Salvador.
Make yourself at home in one of the 10 air-conditioned rooms featuring plasma televisions. Complimentary wireless Internet access keeps you connected, and cable programming is available for your entertainment. Bathrooms have showers and complimentary toiletries. Conveniences include phones, as well as desks and complimentary newspapers.
Take in the views from a terrace and a garden and make use of amenities such as complimentary wireless Internet access. This hotel also features tour/ticket assistance and barbecue grills.
Satisfy your appetite at the hotel's restaurant, which serves breakfast, lunch, and dinner, or stay in and take advantage of room service (during limited hours). Quench your thirst with your favorite drink at a bar/lounge.
Business, Other Amenities
Featured amenities include a business center, complimentary newspapers in the lobby, and luggage storage. Free self parking is available onsite.


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Do you need a new coffee table?
Microsoft's surface hardware enables coders to create amazing interfaces. Is this what the future workplace will look like?
Microsoft's surface hardware enables coders to create amazing interfaces. Is this what the future workplace will look like?
It's definitely time for Xsara to start her own podcast show.
Synthasite offers 1.000 dollars plus a handful of online buzz to the best editor artists. If you're looking for hastle-free, ad-free but free webhosting, this one might be worth a look.
Coldcut and TV Sheriff joined forces to release a great videoclip about the media frenzy caused by the final phase of the presidential elections.
In times of economic crises, a smart dog invests her bones instead of burrying them.
Ladies and Gents, watch the incredible – and animated – fight between DJ Uppercut and a vengefull Ninja. Who will make it to the top of the music video charts?
Today bloggers of the world unite to raise their voice against poverty.
Last weekend the Austrian (and Bratislava) net scene met at HP headquarters Vienna to celebrate barcamp 2008.
Getting some exposure is a crucial task to all webworkers. Blogcatalogue is offering some nice new features which offer very good value for very little money.
HD video editing eats up a lot of computer power – that was a good reason for a hardware upgrade.
The last Google pagerank came as a bit of a shock for most – even Xsara was met totally unprepared on a Sundy afternoon.


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I recently have started doing some more work looking at long term trades - five year investments. While I do love and have had success with short term trading, I also am learning more about long term investing, how to use discounted cash flows, and other long term investing strategies. I have been working and am ready to present today my first major long term report, on Big Lots Inc. (NYSE:BIG). This company is one that I think has lots of potential. I have given the company a fair value estimate, an entry level, and an exit level.
Profile: As of the beginning of 2009, the company operated 1,339 stores in 47 states. The company operates as the largest broad line closeout retailer in the USA. Big Lots offers products in the food, health and beauty, plastics, paper, chemical, pet supplies, home decorative, furniture, electronic, tools, home maintenance, seasonal, toys, infant accessories, and apparel lines. The company is headquartered in Columbus, Ohio.
With the economic downturn and new management in 2005, Big Lots over the past several years has begun to gain market share, increase profitability, and carve out its own niche in the discount store market. The shopping center has seen an influx in its income and free cash flows, which has begun to attract investors to the company. As of recent, the stock has increased at rapid rates with successful quarters. The question for Big Lots, though, is whether or not the company can keep it going. The company has been able to produce consistency in its revenues since Steven S. Fishman took over as CEO and President in 2005, which was rather non-existent prior to his arrival. Additionally, the company has redefined its business, focusing on developing new markets with higher-income residents and smaller stores, increasing its brand name during the economic downturn, and focusing on long term growth by increasing efficiency and margins.
The company, though, does face rigorous competition from three sides. It loses market share from the smaller, dollar-store competition, seen in Family Dollar (NYSE:FDO), Dollar Tree (NASDAQ:DLTR), and Dollar General (NYSE:DG). It faces competition from wholesalers that offer discounted groceries and other goods in Costco (NASDAQ:COST) and BJ's Wholesale (NYSE:BJ). Finally, the mega-stores of Wal-Mart (NYSE:WMT) and Target (NYSE:TGT) steal a sizable market share. Yet Big Lots has been able to maintain a small niche in this market because it does not fit into any of these categories. It is larger in size than the small, convenience-store style of the dollar stores. It is not as large as, the wholesalers (nor does it offer groceries), andis much smaller than Target and Wal-Mart stores. The economic moat is very small, but it does appear that Big Lots has somewhat of a niche in the market as a senior dollar store but a junior Wal-Mart. The company, specializing in closeouts, offers goods that other retailers were not able to sell or kept in inventory for too long. They are the leader in this industry, but their product and price lines are consistent with these three sectors.
Big Lots, because of the economic crisis, has been able to grow a consumer base that it did not have prior to 2007 and is developing itself with new stores. As long as the popularity and necessity of budget-conscious consumers remains, Big Lots should continue to see an increasing market, increases in sales, and increases in the value of its shares. The chain's main positioning mechanism during this time has been the development of both smaller stores that are considerably smaller than current stores and its move into higher-income markets. The company, in 2009 for the first time, opened more stores than it closed due to its ability to expand, increased free cash flows, and increased demand. The company opened 52 new stores in '09 and is planning to open 80 new stores in 2010 and 100 in 2011 and 2012. The move into higher-income markets may be the most beneficial part of Big Lots' plans for development. Big Lots entered "A" rating locations, which refers to high-income retail areas. Inexpensive commercial real estate allowed the discount store to open eight new stores in the "A" rated areas, and they plan to continue that development with 24 more in 2010.
The company, additionally, has been redefining their business structure in order to increase their operating margins. On a ten-year average, the company had margins of 3.16% and ROA of 2.14%. In looking at just the past five years, the company has turned their margins into 3.24% and return on assets into 5.74%. The company has been able to decrease expenses as companies have continued to have excess inventory and lower prices. The company stresses it has remained profitable with tight inventory management and by offering assortments of goods that consumers want. The company's efficiency results reflect such claims as the company has improved its inventory turnover significantly. The ten-year average is 3.03 times per year versus a five-year average of 3.44.
Competition, however, still remains very tight in the industry. The company will have to continue to improve inventory management, understand trends in what consumers want to buy, offer the right assortment of goods, and continue to improve its efficiency. Discount retailers, however, all have their sights set on expansion in the economy, and they will continue to crowd the market. While Big Lots has taken many of the right steps to begin to carve out a small niche and expand into new markets that will benefit the company significantly, the improvement of the economy, the lack of long-term consistency, and competition present significant challenges to Big Lots. The size of its stores and diversity of goods it offers, however, will continue to set it apart from other discount retailers. As the company enters new markets, they are gaining brand name recognition in these areas that will help to continue their successes post-recession.
My fair value estimate for Big Lots is $33.14 per share based on the attached discounted cash-flow analysis. The company has seen incredible growth in its operating income in the past five years, averaging over 96% year-over-year. While these growth rates cannot be maintained long term, the company should be able to see continued growth on its operating income of 8% over the next five years. Given the development of new stores and new markets, the continuation of the economic downturn, and continued growth of same-store sales that was 0.7% in 2009, the company should continue high single-digit growth in its income. The company is estimating operating cash flows of nearly $200 million in 2010. I have started my estimated available cash flows lower, at $160 million, to help remain cautious in an emerging company that may be setting the bar too high on too few consistent years. With questions on competition, however, and a post-recession economy, 8% is a modest assessment that is including a significant amount of caution, considering a maximum bear case. Operating margins should continue to be in the low-single digit range over the next five years. The company continues to increase its efficiency but continued competition and upturn of the economy will keep these in check.
Risk is definitely high with Big Lots. The company, in the last five years, has started to truly redevelop and reinvent itself. New CEO Fishman has kept the company moving in the right direction with a long-term growth development plan, but competition remains very high. The company's economic moat is not significant, as well. Additionally, low-income consumers have less consistency in purchases than high-income consumers. The movement into new, "A" grade markets does help hedge some of this risk, but the company still has the majority of its operations with low-income families. Upturn in the economy, decline in unemployment, and continued price slashing at other retailers will continue to threaten Big Lots' recent success.
Management & StewardshipClick to enlarge
CEO Steve Fishman has done some very admirable work with this company. A retail industry veteran, he has thirty years' experience as former CEO of three companies, Rhodes Furniture, Frank's Nursery & Crafts, and Pamida, which he successfully restructured and helped bring into profitability. His experience in restructuring has helped Big Lots thus far. One issue, though, with management is that with the recent success the company has experienced, Fishman and other executives have seen significant increases in pay. Executive compensation grew from $8.74 million to $15.71 million from 2006 to 2008. The pay is in line with competitors, but the growth is still something to keep in mind. Further, Fishman has seen a tripling of his compensation package since 2006. Additionally, it would be better if there were a split of the chairman and CEO positions that Fishman currently holds. The board is independent.
Growth: The company has averaged 90% increases in its operating income in the past five years and over 40% in the past ten years. These results, however, have been very erratic. The company should settle into a high-single digit operating income growth rate as it continues to grow revenue and decrease expenses.
Profitability: The company should continue to maintain its operating margins in the 3-4% range. The company is facing continued competition and will see increases in commercial real estate prices. Gains should be made, though, by the introduction into higher income areas.
Financial Health: The company is in very solid financial condition. The company has increased free cash flows, no long-term debt, and a solid current ratio. The company does have some worry that its quick ratio is averaged at 0.25 over the past five years. The company has a very solid interest coverage ratio with EBIT 50 times interest expense in 2009.
Fair Value Estimate - $33.14 (estimate of price in five years)
Consider Buy - $24 - $25
Consider Sell - $45 - $46


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Utah was recently invited to leave the non-BCS Mountain West Conference and join the PAC-10. This is a wonderful lift for UTAH, but it begs the question of what makes a team BCS worthy and why isn't every FBS program allowed to compete at the same level in Bowl Season? Why UTAH and not someone else? Why Louisville, Connecticut, South Florida and Cincinnati (two of those programs only having become FBS programs in the last decade or so)?
Well, we wont cover the illegalities of the BCS or it's inherent anti-competitive nature here. Maybe in a more serious article another time. But it does force us to take a look at some of the inequities in college football and wonder which programs are being shunned and financially damaged by the current BCS? Which programs are being left out by reason of their mission statement or geography (or both).
Here is a look at just 12 programs that should be members of BCS conferences and why! It is terribly unfair that they are not. Seven other programs not included that maybe should have been are Tulsa, UTEP, UNLV, Colorado State, Memphis State, Troy State and East Carolina.


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Shredder Oil & Waste Sacks for the HSM SECURIO P44 - Why oil your shredder? / Why use waste sacks?
S4 HSM P44 Waste Sacks
Pack of 50
£34.95 (x1)
£62.92 (x2)
£139.80 (x5)
(All + vat)
HSM Shredder Bags (XL Clear)
Pack of 25
£37.95 (x1)
£68.32 (x2)
£151.80 (x5)
(All + vat)
£7.95 (x1)
£28.64 (x4)
£63.60 (x10)
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£10.95 (x1)
£39.44 (x4)
£87.60 (x10)
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HSM Shredder Oil
250ml Bottle
£15.95 (x1)
£28.72 (x2)
£63.80 (x5)
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£16.95 (x1)
£61.04 (x4)
£135.60 (x10)
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Product Details
The HSM SECURIO P44 1871 is a 5.8mm Strip Cut shredder and the Highest Capacity Departmental Shredder on the Market today. The machine is a Mobile, High performance model designed for entire Departments and Large Office Floors. It has a strip cut security level of P-2. For High Security Level 5 and 6 please see the SECURIO P44 HS.
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Office Model
This machine is designed for heavy usage by a single user or shared office space.
Specifications are subject to change - See Terms & Conditions for more info


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I recently purchased a ruger m77 30.06 appears to be circa 1971-1973 possibly the scope rail is milled into the reciever there is no t under the bolt handle no warning on the barrel just sturm ruger & co inc. it also is in great to excellent condition having only minor aesthetic dings. it also has a bushnell scope sportview wide angle 9x also the gun is very light weighing in around 7.5 lbs with scope . no black on gun any where except ruger emblem under pistol grip portion of the stock, with the exception of the bluing of the barrel and components. i would like an approximate value of the rifle w/ and w/o the scope.
appears to be circa 1971-1973
no warning on the barrel just sturm ruger & co inc.
possibly the scope rail is milled into the reciever
the gun is very light weighing in around 7.5 lbs with scope
has a bushnell scope sportview . . . i would like an approximate value of the rifle w/ and w/o the scope.
yes sir that helped alot any way to tell if this has the douglas barrel the only engraving on the barrel say sturm ruger&co inc and some punctuation with it. also closer to the receiver is .30-06 maybe one proof mark would have to take another closer look.
Excellent question! Unfortunately, I don't believe Douglass marked the barrels in any identifiable way. I just checked my examples and neither the Douglass nor the Wilson are marked. My guess is that Ruger specified that they not be so marked when they ordered them (but that is just a guess).
The Ruger folks are pretty accommodating. You might try using the email query address found on the company website. Give them the serial number and see if they will tell you who manufactured your barrel. I have never asked this question, but when I have sought information from that source, they have always returned my email courteously and promptly and have been very forthcoming with information. So far as I can tell, this has not changed, even with Bill Ruger's passing.
The only issue would be whether specific records were kept that would allow them to answer the question factually, but I strongly suspect they will know.
Good luck. And if you find out anything, please let me know.
ok so i am still waiting on ruger to tell me however did some more research and what i have found is that ruger no.1 and m77 up to 1973 or 70-45000 serial would have a douglas barrel. Guess my question is how would having a douglas barrel affect the price of the gun. It was previously appraised at or around 500.
Yes, that time frame is correct. Sometime in late 1973 or early 1974, Ruger switched to Wilson barrels. The exact date is probably a little squishy, because they would have used up stock on hand.
In my opinion and experience, guys who care about this stuff will pay a premium for a gun known to have a Douglas barrel. Wilson's QC just was not up to the same level and some Wilson barrels have trouble hitting a barn side from indoors - others are quite accurate, but that's the problem: you can't know until you shoot a few rounds through one from the bench. We never had this problem with the Douglas barrels.
Personally, I would gladly pay a $100 premium for a Douglas barreled M77 over a Wilson barreled example in the same condition. The Average Joe gun buyer might not (and this includes some gun shop owners). As previously stated, I think $500 is an excellent price for a Douglas-equipped M77, from a buyer's perspective. If you plan to sell this gun, I would suggest pricing it at $600 or more.
Also, don't forget that we are talking private sales here. If you take it to a pawn shop or local gun shop, they will not even begin to offer you full value. They can't. They are in the business to make money, so they have to be able to mark the gun up for resale.
I hope this is helping you think through the issue.
been very helpful thank you very much!
I see this is an old post. But it was somewhat helpful to me. I've aquired a mint condition 1968 Ruger M77 serial number 1079, chambered in .243 Win from my father who was given it new by his father in 68. It also has the original Redfield 3x-9x scope on it, which is also mint. Is there any value info you could give me on the rifle. I would assume being a first year production model, and being that it is in 90-100% condition, that it would be worth more than a newer model...
I don't think the "first year" thing really makes any difference. Guns are not stamps or coins. The market simply does not work like that in most cases.
However, as explained above, the fact that it almost certainly has a Douglas barrel will make a difference to those in the know. The problem is finding someone who understands the production history. I would give you the same advice I gave the previous writer.


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Weathervane Red, White, and Blue Specials Friday, July 4, 2014 at 7:00am While you're here enjoying Our Famous Red, White, and Blue Party, stop by Weathervane Restaurant to take advantage of these Independence Day Specials: $5 Pancake Breakfast from 7-10 a.m. with your choice of blueberry, chocolate chip, or classic pancakes and a side of sausageFind out more »
The festivities begin at 9 am with a parade along West Tryon Street; prizes will be awarded for Most Patriotic, Most Patriotic Pet, and Most Hillsborough. Then, at 10 am, a public reading of the Declaration of Independence at the Old Orange County Courthouse will celebrate 238 years of American Independence. From there the festivitiesFind out more »
Come and join us in a fun filled community celebration of the 4th of July! 9:30 am - 4pm at Carrboro Town Commons and Weaver Street. Music, food trucks, kids games and activities all day long. Starting at 9:30 at Weaver Street is a bike decorating and costume contest for all ages. Parade from WeaverFind out more »
Kick -off Event at Weaver Street Market co-sponsored by Weaver Street Market 9:30 a.m. - 10:50 a.m. Followed by the parade to the events at Town Hall and Commons 9:30 a.m. Music Tim Stambaugh and the Bull City Strutters 9:45 a.m.Designing and Decorating Booths Open Patriotic Tattoo Booth Hat Making and Decorating Patriotic Flag Coloring BikeFind out more »
Music at The Festival for The Eno Music and other fun family events!Find out more »
The American flag will be flying high at our annual Red, White & Blue Party! Before staking out your spot for the fireworks display, stop by our store from Friday, July 4 from 11 a.m. to 3 p.m. for a family-friendly celebration, Live Music, and tons of delicious tastings! Kids will enjoy outdoor games, likeFind out more »
Allow our restaurant chefs and Cooking School instructors to inspire culinary creativity for your weekend gatherings and happenings. On the first Friday of every month, stop by our Cooking School from 11 a.m. to 2 p.m. for cooking demonstrations from our favorite magazines, cookbooks or local chefs. Each recipe will highlight the endless offerings inFind out more »
The Town of Carrboro is pleased to announce that it will be holding a Community Reading of Frederick Douglass' essay, "The Meaning of the Fourth of July for the Negro" on July 4, 2014. The reading will occur in the Town of Carrboro Board Room from 12:00 noon - 1:00 p.m. Please note the readingFind out more »
The Chapel Hill Parks and Recreation Department is sponsoring its annual Independence Day Celebration, an outdoor fireworks display with live entertainment and fun for the whole family! The July Fourth Celebration draws thousands of people to historic Kenan Stadium and has grown to become one of the largest, most prestigious, free outdoor events in the Triangle.Find out more »
Local Buzz, Triangle For Squares: A social media-inspired hyperlocal sketch comedy revue. UPCOMING SHOWS: FRIDAY 6/27 7PM (Buy Tickets) FRIDAY 7/04 7PM (Buy Tickets) FRIDAY 7/11 7PM (Buy Tickets) FRIDAY 7/18 830PM (Buy Tickets) FRIDAY 7/25 830PM (Buy Tickets)Find out more »
The Doug Largent Trio featuring Brad Maiani on guitar and Dan Davis on drums plays organ trio jazz at West End Wine Bar of Chapel Hill.Find out more »
Blood Red River Everymen, Matthew Paul Butler Fri, July 4, 2014 Doors: 8:00 pm / Show: 8:45 pm Local 506 Chapel Hill, NC $5.00 - $7.00 Tickets Facebook Share On TwitterFind out more »
DSI's flagship show features true stories told by a local celebrity or special guest. Those anecdotes inspire a world of captivating scenes, fully improvised by the most aggressive improv comedians in North Carolina. MISTER DIPLOMAT has been making audiences laugh since 2003. From local crowds at Inside Scoop, Skylight Exchange, Kings Barcade, The ArtsCenter, andFind out more »


text:
Probiotics Help Save the Spine
Sounds of Science Podcast
Humanizing Animals for Immuno-Oncology
Success in Humanizing Mice Has Inspired Similar Efforts in Rats, Pigs, and Other Animals
Molecular Dx Has Your (Copy) Number
CNV Detection and Analysis Tools Are Being Used To Fill Genetic Diagnostic Gaps
Transcript-Savvy Discovery Is a Smart Bet
Drug Developers Are Finding Ways to Bend the Transcriptome to Their Will
For full access to this article login to GEN Select now.
February 01, 2011 (Vol. 31, No. 3)
Cell-Based Assays Move to Fore
Cell Quality, Growth Environment, and Analytical Capability Upgrades Are All Being Pursued by Companies
- With an estimated 90% of lead candidates from in vitro screens ending up as also-rans—despite the spiraling costs of development—new ways of eliminating these candidates earlier in the drug discovery process need to be developed. A major theme running through Visiongain's recent London-based "Cell Based Assays" conference is that ...
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They look clean and simple...But also fake...
New Videos
Subscribe to the Sneaker News Youtube Channel
June 20, 2012 BY Aaron Hope / 10
It's been an interesting month or so for unreleased Air Jordan V samples, starting back in late May with the orange 'Rainbow Pack' selection and bookended by a couple of elegant if simple black suede designs. This new look features upper construction similar to the pair we viewed last week, but the addition of a white lining and midsole makes the overall impact far more of an 'Oreo' (there's even a bit of speckling on the shark teeth) than the earlier design's 'Blackout'. Click through for a better look at this relatively plain wear-test sample, let us know which of these classy black Air Jordan 5s you would more like to have in your collection and stick with Sneaker News for more rare Air Jordan samples. via Artaphax
Filed under: Air Jordan Sample
Tags: Air Jordan V
They look clean and simple...But also fake...
Pretty ugly. It still would've sold out though if it dropped. Real shit. LMAO
If it was reversed I think it might look good. White upper with black accents and a black midsole. This though, ew
That midsole makes it look like a team Jordan spin off
I'd rather look at Octo-mom nude then these hideous things
The white midsole makes these look awful!!!!!
nah these are ugly as hell to me
No more black 5s...please
Thank God these were jus a sample
mayb not for everyone but i think i would cop......they look too "fake" in the pic though
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text:
1930s St. George and the Dragon Brooch - Vermeil
browse these categories for related items...
Directory: Estate Jewelry: Costume: Unsigned: Pre 1940: Item # 1197471
Directory: Estate Jewelry: Costume: Unsigned: Pre 1940: Item # 1197471
Please refer to our stock # TC1024 when inquiring.
The Pink Lady Collection
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Guest Book
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Guest Book
This is a very old brooch depicting St. George and the Dragon in gold plated Sterling, with simulated pearls and a sparkling rhinestones. The top is a fancy metal bar about 1" wide with a stone in the middle that appears to be amethyst glass. The total length of the brooch is 3" and at the widest part it is 13/4" wide. St. George and his horse are decorated with clear rhinestones and the dragon has three red stones at the bottom. There are also simulated pearls that hang from the top bar and from the bottom of the figure. A couple of the bottom ones have small spots that appear to have been caused by rubbing against the metal rings that hold them. Other than that the pin is in excellent condition considering its age. Most people know the story of St. George who killed the dragon, and they also know that St. George is the patron aaint of England, and has appeared on coins from that country. Legend has it that English soldiers carried with them Thaliers (coins) depicting St. George with them into battle for protection. I'm not sure about the legends, but I do know that this pin is very old, in excellent condition, and marked Sterling, as shown.
Similar Items from this seller
|190s Red Lucite "Moon Glow" Bracelet
|Unusual Faux Pearl Cocktail Ring
|Art Deco Glass and Brass Pendant Necklace


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Were the fag face company that cant do shit at all we dont know how to make sucess
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Click here for the High School Football Game of the Week Schedule
Tampa Bay Rowdies vs. Miami FC - Saturday at 7:00pm on BHSN
Local high school teams are showcased live, only on Bright House Sports Network. Check out the first-half of our 2016 Game of the Week football and volleyball telecast schedule!
Copies of BHSN games can be purchased from:
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Attention, high school seniors: BHSN wants to help you pay for college. Click here to learn more about the David Logan Scholarship and apply now!
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Telephone: (727) 329-2447
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Orlando, FL 32801
Bright House Sports Network is the Official Television Partner of the Florida High School Athletic Association! Visit the FHSAA's website for a listing of sports and state championship schedules.


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32 years of experience
Accepting new patients
Video profile
Wilmington, DE 19803 Phone number & directions
Patient Reviews
Patient Reviews ? Write a Review
Overall Rating:
Total Ratings
Total Reviews
Best doctor I've every known. He is kind, compassionate and truly cares about his patients and their families. He was wonderful while we went through a very difficult time when my daughter was going through her cancer, synovial sarcoma biphasic.
My son has Spondelo metaphaseal dysplasia and has been seeing Dr. Mackenzie for 4 years. My son has had 3 surgeries and Dr. Mackenzie has been extremely supportive throughout his treatment. I'm a major fan of Dr. Mackenzie and appreciate his expertise and devotion.
Dr. MacKenzie treated my daughter's scoliosis for several years, from age 12-18. He won our family's trust immediately. Very caring and attentive. She ultimately needed spinal fusion surgery, which was a very scary prospect. He prepared us all, we knew exactly what would happen and what to expect..It was a tough experience - spine surgery is no picinic - but the results were fantastic. I would recommend Dr. MacKenzie to anyone.
Dr. William Mackenzie is one of the best surgeon's that I have ever had the pleasure of working with. Every parent who has had a child that has to endure surgery understands the worry and stress that you experience. The last thing that you want to deal with is a surgeon that is just there for the surgery & doesn't connect or understand-in the case of Dr. Mackenzie, who by the way is one of the top orthopedic surgeons in the world this is ABSLOUTLY NOT the case! He is an amazing surgeon who not only connects with the child but the parents as well. He has a personality that that is both warm and charming. When you are talking to him you know that he is listening. His "bedside manner" is one that very physician should use as an example on how to treat patients and parents. More importantly, however, is his expertise in the operating room. Dr. Mackenzie is a phenomenal surgeon- My child has had the honor to be a patient of Dr. Mackenzie for a number of years now, his orthopedic issues are unique and complicated. Dr. Mackenzie has done an amazing job-every child to him is unique and special and the care that he provides and understanding and compassion that he show is breath taking. He in my eyes is the best! I highly recommend him~


text: Tony Reynes has offered to take some of your images and work his Photoshop magic on them. Post an image to the "Images for Critique" section of our Google+ community and Tony will pick some of his favorites to work on in Photoshop. Choose whatever images you want. It may be your favorite, your least favorite, or one that needs a little help. Along with your post, you may want to add a comment or questions. In the coming weeks, Tony will publish an article showing what he did to the image and why.


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Every July it happens. The lure of the beach and chicken parmesan sandwiches beckons, and my colleague Tristan H. Cockcroft is unable to resist taking a well-earned week off before trade-deadline moves change the baseball landscape to the point where one cannot afford to look away. Once again, I have been asked to fill the huge void left by his absence, and I'll try my best not to blow this save situation...
Which Closers Are Safe ... and Unsafe?
From ESPN.com
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Joey Tartell is not only a great player and teacher, he expresses himself very well.
Here is one of his recent blog posts:
Radical Moderatism | Tartellog
Joey Tartell is not only a great player and teacher, he expresses himself very well.
Here is one of his recent blog posts:
Radical Moderatism | Tartellog
Ivan Hunter
Performance and Tuition - Design, Modification and Repair
Jaeger Trumpets, Cornets and Mouthpieces
Please do not attempt any repairs unless you have appropriate technical proficiency
Program facilitator for
Bringing Music back into the Home
Nice article.
'My advice is to never do tomorrow what you can do today. Procrastination is the thief of time.'
- Charles Dickens
Bb Trumpets: Yamaha YTR-6335HSII - Flip Oakes "Wild Thing" - 1972 Getzen Eterna "Severinsen" - 1980 Boosey & Hawkes Sovereign Studio - B&S 3005 WTR-L - 1963 Besson 10-10 - Monke Mystery Horn - Spiri Vario
C Trumpet: Inderbinen Alpha 200
Bb Bass: 1961 Holton #58 "Symphony"
Wyrd oft nereð unfågne eorl, þonne his ellen dëah.
"Pypes, trompes, nakers, clariounes, that in bataille blowen blody sounes"
Nice article.
The problem, of course, extends way beyond music. We like to polarize people with extremes, because it gives a reason to argue, to bully, and to feel superior.
It's unfortunate. But because of this, I doubt "radical moderatism" will catch on until we practice "radical empathy". We don't have to agree with the other guy. But we need to empathize/understand/respect where the other guy is coming from. And the more we disagree with that person, the more we need show empathy towards him/her.
Bach Stradivarius 43* (1974), Bach 3C Mouthpiece.
Getzen 896 Eterna Flugelhorn (1974), Curry 3FL Mouthpiece.
Plus a few other Bach, Getzen, Olds, Carol, and Besson horns.
I think that we have problems with radical because we have become emotionally too soft, intolerant of raw truth. I think the problem is more the wimp than the radical.
Just check mother nature in her purest form out. Survival of the fittest, rewards to those that can adapt. Argue with a hungry lion, explain why it is unfair.......... You need pretty good arguments, or strong legs. The lion is never wrong.
Whenever I feel blue, I start breathing again.
(tongue-in-cheek warning)
At the risk of sounding too extreme ...
Hasn't "survival of the fittest" been redefined by modern scientists? Open competition is believed to result mutual destruction, not survival of the fittest. In nature, a cooperative and adaptable species (dare I say "moderatism") has a greater chance of survival than a selfish and competitive species.
Bach Stradivarius 43* (1974), Bach 3C Mouthpiece.
Getzen 896 Eterna Flugelhorn (1974), Curry 3FL Mouthpiece.
Plus a few other Bach, Getzen, Olds, Carol, and Besson horns.
Yes, "survival of the fittest" has been raped by the same type of ANALysts that helped the banks and politics in all directions crash. The idiocy is that it is possible to look at short term suppression and call that success or being "fitter". The truth is that only when the victim happens to die short term do the suppressors get away with it.
Selfish is not fit, it builds enemies. Competitive CAN be healthy. Lions do not kill one another over food unless something else is terribly wrong.
As applied to the trumpet, you have to produce the goods if you are going to have an attitude. A teacher with an attitude will have no students if they get beaten up and don't get better........... A teacher with an attitude passes that attitude on when things work. I am not a first generation "ass".
Whenever I feel blue, I start breathing again.
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Real Life Adventures by Gary Wise and Lance Aldrich
- October 01, 2012
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Comments (2) (Please sign in to comment)
So is it too late to
A: buy a hat
B: practice throwing a bit, then
C: throwing his hat into the ring?
Are you popular enough to get fundraisers to support you? Or do you have a truckload of money to pay for a campaign yourself? Hmm, maybe that's what the guy in the comic meant.
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