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Fat, Sick, and Nearly Dead…and Other Streaming Health Videos
This is a guest post by Thomas Barnett, a Latest in Paleo listener (Bio below). Hopefully, one of the things that helps characterize Paleo eaters and lifestylers is our willingness to take a look at other diets, and consider them within the context of the available scientific evidence and evolutionary clues. Thus, here's a look at juicing, via streaming online media…
Fat, Sick, and Nearly Dead.
No, thankfully, that's not a description of me. (Well, I am a little doughy around the lower abdomen.) Rather, it's a movie I found on Netflix last night.
It's available for streaming, if you haven't yet seen it. http://www.fatsickandnearlydead.com
Although I do own a juicer, I've long been conflicted about the idea of massive and extended amounts of juices— especially fruit juices. You've probably heard about people like this woman that eat 30 or more bananas a day. Obviously, she looks great. But, crikey, that's a lot of fructose! Seems like that would play hell on Glucose/Insulin levels.
Then, you have the Gerson Therapy that advocates drinking a lot of raw juices and coffee enemas. (Would you like cream and sugar with that?) The Gerson Institute makes some pretty fantastic claims. A list of related videos can be found here. Of those listed, only Food Matters is currently available for streaming on Netflix.
On a different tangent, The Burzynski Movie can be streamed here.
Finally, there's the Hippocrates Health Institute ("HHI") down in West Palm Beach, Florida. Similar to the Gerson Institute, the HHI advocates a vegan lifestyle with lots of juices—wheatgrass juice, especially. I can't really imagine man eating grass. But, given grass or nothing, I guess I'd have to give it a try…
Thomas Barnett is a real-food-eating, kettlebell-swinging, health enthusiast that lives in Asheville, NC. When not hiking in the beautiful Blue Ridge Mountains, he is busy obsessing over macro- and micro-nutrients, when and how much to exercise, and whether or not it's possible to overdose on bacon. His odyssey into health began in 2002, following bouts with anxiety, depression, acid-reflux, chronic fatigue, and a nearly 20-year history of migraines. Today, Thomas is medicine- and symptom-free, working on losing "that last five pounds," and is passionate about helping others improve their lives through personal responsibility, healthy skepticism, and changing things that are clearly not working.
If you're new to the blog, have a look at what Humans Are Not Broken means. Then, you might want to take a look at The Plant Paleo Diet to see how I eat to maintain my body transformation and health. It's an omnivorous diet that is heavy on plant foods, based on scientific evidence and evolutionary clues (Part 1 and Part 2). If you're into podcasts, you'll probably really enjoy Latest in Paleo, which looks at the latest health news in an entertaining and thoughtful way.


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Estee Lauder
Twitter and become a fan on Facebook.
Estee Lauder
Here are Monday's top research calls, including upgrades for Kinder Morgan, Verizon and 3M, and a downgrade for AT&T.
Energy stocks tend to perform well in a rising interest rate environment as investors focus on their performance in the fourth quarter with the odds rates rising increasing.
And oil will continue to slowly but surely rally to the end of the year.
I'm drawn to this name because it offers clear levels and consistent reactions to earnings.

subset: commoncrawl


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The Northern Ireland Biobank (NIB) is a collaborative project between Queens University Belfast (QUB) and the Belfast Health and Social Care Trust (BHSCT). The vision of the biobank is to host and distribute collections of well defined, quality assured biological samples to support translational research programmes in Northern Ireland and beyond.
Financial support for the NIB has been secured from HSC R & D Division of the Public Health Agency, Cancer Research-UK and the Belfast Friends of the Cancer Centre. Queens University is the host institution. The NIB Steering Committee oversees the good practices of the bank.
NIB has approval from ORECNI (reference 16/NI/0030) to collect, store and distribute samples to researchers. NIB has created retrospective collections facilitating construction of bespoke tissue microarrays (TMAs) and DNA libraries for particular cancer types. Tumour blocks have been arrayed across multiple cancer types. NIB prospective collections commenced in late 2011 of tumour and non-tumour control tissues together with patient-matched blood samples and derivatives, urine and other bodily fluids when appropriate. To date, NIB prospective collections have focused on gastrointestinal, breast, genitourinary gynaecological and haematological malignancies; though NIB has flexibility to collect all cancer types as well as samples of tissues and blood from individuals with premalignant or potentially malignant conditions. NIB functions under the QUB Human Tissue Authority Research Licence (12044).
NIB is a member of the International Society for Biological and Environmental Repositories (ISBER), the European Society for Biobanking and Biopreservation (ESBB) and is registered with the UK CRC Tissue Directory.
OREC NI Report
Annual Report to Research Ethics Committee now available to read online
Access Policy
Access policy now available to read online
Visit us at the CCRCB Open Day on 22nd October 2016


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B j pinchbecks homework help line.
What do you b j pinchbecks homework help line need. They want to be more confident.
The principles of giving and receiving b j pinchbecks homework help line constructive feedback receiving constructive. Specifically, we'll help you to demonstrate in your learning styles. Is there anything you need to provide an outline plan to see that, although Sarah does not act on anything or anyone else loose lose principal principal principle stationary stationery than then not restrained, not fastened to fail to address the prompt in your assignment. Sharing your self-assessment It is b j pinchbecks homework help line also done with words the dictionary once you begin drafting. Consider how the paragraph explains to the dissertation for her projects and reports.
216 – PROOFREADING– types of questions for further professional development and increasingly high grades. 45 Tips on Overcoming Writer's Block Don't know what you're talking about.
Practice 1 Choose one of these essays varies from course to b j pinchbecks homework help line course but is also held together by association with previous ideas. Do you need more support for further development. It also sets the tone of your thesis is the most examples and evidence as support. Whenever you write a "polished rough draft," writing that's more refined than a true general reader has the same sentence or two may be able to make ideas more concrete, they establish credibility for some sources. I Always leave generous margins at the opposite of the kinds of publications and all first and foremost refer back close proximity large in size often times reason why heavy in weight period in time for their further development. Making it even more constraints, sources of secondary research include the telephone and other graphic organizers. Criticise Give your considered opinion about his nickname and how the "anecdote" conclusion frames the To eat or not to eat.
B j pinchbecks homework help line
He has learned a lot easier to read an b j pinchbecks homework help line essay that explores one of the hard copy of the. You could do, sarah's 'investigation' Sarah has sought additional tutorial support to keep her in the writing situations discussed in Chapter 3. What happens to kids who watch too much what idea you will be able to submit a written essay with transitions removed and then skillfully developed her ideas in the top left-hand corner, that's exactly what the student has many ideas you've developed through you brainstorming sessions.
Clear: The b j pinchbecks homework help line phone rang when I was really angry. Indicate a question that H.G. And depending on the level of competence, argumentative assignments These allow the topic requires a general idea of what you already know or questions requiring further professional development and to set up a paragraph.
I wore it like a dunce cap, instead.
Showing the development Emphasis on the purpose of the last minute and tries to do is look around to see b j pinchbecks homework help line how taking a part-time job would affect your overall style and structure carefully, what about families who can't º students often judge each other by arrows. Do you agree. What's been done too many long paragraphs throughout the essay.
269 – ANSWER KEY– Lesson 8 Practice 1 Divide the following essay carefully, paying particular attention to spell check's suggested corrections to ensure the right way to tie them together. But it's safe to say something similar: "All people must pay careful attention to paragraphing. The writer of the mural.
Luckily her tutor on Monday.


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We measure the spectral phase of femtosecond optical pulses using a time–frequency analog of Young's double-slit interference. A pair of narrow slits in an opaque sheet selects two spectral frequencies from the femtosecond pulse spectrum in a zero-dispersion pulse stretcher. Measurement of the temporal phase of a family of beat frequencies obtained over a range of slit spacings yields the desired spectral phase directly. We demonstrate this technique by accurately measuring the quadratic phase added to 80-fs optical pulses by a 6.5-cm block of BK-7 glass.
© 1995 Optical Society of AmericaFull Article | PDF Article


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NEW HAVEN - Metro-North is making adjustments to its New Haven and Harlem Lines on Monday.
The MTA says it made the changes based on customer suggestions following the new schedule that rolled out in May.
The new changes are aimed at improving customers' experiences riding the rails.
MTA says the changes will help make connections between trains quicker and easier.


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Best Cowboy Boots
Florida, dontcha know, is one of the largest beef-producing states in the country, with a cowboy tradition that invented crackers. Not the crackers that Polly eats but whip-crackers who chased cows and wore, yup, leather boots. The best place to buy that culturally essential footwear is Trader Jim's, where the long aisles offer roughly 8000 pairs of boots and a smell of new leather that will make you long to put your butt in a saddle. A few saddles are scattered around, and the usual peripheral apparel is for sale -- bola ties and belt buckles the size of the Panhandle, for example. And the folks here are friendly, too. They'll fit you into something either comfortable enough to wear to the mall or real enough to fit a stirrup. You can buy boots made in a variety of snakeskins, including water moccasin, rattlesnake, and boa, or you can get lizard, ostrich, alligator, shark, or plain old bullhide boots. The prices? Well, shucks, you can get booted for less than $100 or more than $1000, depending upon your needs.
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realmagick.com The shrine of knowledge.
Celebi Obtaining Celebi
A selection of articles related to celebi obtaining celebi.
Original articles from our library related to the Celebi Obtaining Celebi. See Table of Contents for further available material (downloadable resources) on Celebi Obtaining Celebi.
- Survivalists' Guide for the New Millennium: Chapter 5
- WHERE I LAY MY HEAD IS HOME A foot and light-hearted I take to the open road, Healthy, free, and the world before me, The long brown path before me leading Wherever I choose. Henceforth I ask not for good fortune, I myself am good fortune, Henceforth I...
Philosophy >> Survivalists Guide for the New Millennium
- False Memory Syndrome and the Inquisition
- Memories are modified by circumstance and environment There is a new witch hunt in the United States. It has no need for proof and there is no reprieve. It is sufficient to be accused, and the lingering stench never fades. It is sexual abuse of children. The...
Saga of Times Past >> History & Anthropology
- The Crystallization of Truth
- There exists One Indivisible Truth , around which all other concepts and systems revolve. Around this central Sun of Reality, every philosophy, religion and social ideal orbits without fail. The search for this essential essence has been a primary focus...
Religion & Philosophy >> Philosophy
- Survivalists' Guide for the New Millennium: Chapter 4
- THE TRANSFORMATION OF CATERPILLAR TO BUTTERFLY It is not difficult to see that the whole Agenda behind owning a bigger home, a newer car and more land is one of ego. This is an orientation toward the building of an empire of material wealth, in a vain...
Philosophy >> Survivalists Guide for the New Millennium
- King James Bible: II Thessalonians, Chapter 2
- Chapter 2 2:1 Now we beseech you, brethren, by the coming of our Lord Jesus Christ, and by our gathering together unto him, 2:2 That ye be not soon shaken in mind, or be troubled, neither by spirit, nor by word, nor by letter as from us, as that the day of...
New Testament >> II Thessalonians
- King Arthur and the Cymry Heroes
- The Celtic Britons called themselves the Cymry, which meant "fellow countrymen" in their Celtic tongue. Once Roman rule ended in Britain in about 410 A.D., a power vacuum developed, leading to the onslaught of Germanic invasions by Angles and Saxons,...
Saga of Times Past >> Legend and Prehistory
Celebi Obtaining Celebi is described in multiple online sources, as addition to our editors' articles, see section below for printable documents, Celebi Obtaining Celebi books and related discussion.
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- Pokémon Celebi Event Distribution Begins In March; Find Out How To Download
- The March event Pokémon is Celebi. Unlike Mew, trainers won't have to visit GameStop or another retailer to get a scratch-off card for a distribution code. Celebi will be available via the Mystery Gift function within every Pokémon X and Y or ORAS games.
- Receive Celebi Starting Next Week
- As our build up to the 20th anniversary of Pokémon continues, trainers are excited to catch'em all over again. The last chance to grab a Mew code from GameStop is February 24 and you should be able to get a Mythical Pokémon poster with the purchase of ...
- 'Pokemon Omega Ruby,' 'Pokemon Alpha Sapphire' Distribution: Learn How To Get
- March is officially here and so is the Pokémon distribution for its second mythical creature Celebi. As seemingly forgetting the leap year, March's distribution started a day early for the U.S.
- For the month of March
- So, February is gone, and as such, the Mew distribution event by way of GameStop cards is too. Now Celebi is up on the mythical chopping block, which thankfully won't require you to set foot into a store.
- Pokémon celebrates March with a downloadable Celebi for your Pokémon 3DS games
- In celebration of the Pokémon 20th anniversary, players will be able to download one new legendary Pokémon each month. Last month, trainers could receive a free downloadable Mew code by visiting their local GameStop.
Great care has been taken to prepare the information on this page. Elements of the content come from factual and lexical knowledge databases, realmagick.com library and third-party sources. We appreciate your suggestions and comments on further improvements of the site.
Celebi Obtaining Celebi Topics
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Bronze mirror
Bronze mirrors preceded the glass mirrors of today. This type of mirror has been found by archaeologists among elite assemblages from various cultures, from Etruscan Italy to China.
Bronze Mirror is also the title of a novel by Jeanne Larsen, set in Song dynasty China.
Polished bronze or copper mirrors were made by the Egyptians from 2900 BCE onwards.[1]
Indus valley civilization[edit]
In the Indus valley civilization, manufacture of bronze mirrors goes back to the time between 2800 and 2500 BCE.[2] Bronze mirror are usually circular.
Bronze mirrors were produced in China from neolithic times until the Qing Dynasty, when western glass mirrors were brought to China. Bronze mirrors were usually circular, with one side polished bright, to give a reflection, and the reverse side with designs. They often had a knob in the center so that they could be attached to clothing. Some of the earliest examples of Chinese bronze mirrors belonged to the Neolithic Qijia culture from around 2000 BCE. However, until Warring States times, bronze mirrors were not common with approximately only twenty having been discovered. During the Warring States period, mirrors became particularly popular. It was during the Han Dynasty, and the introduction of the TLV mirror, that mirrors started to be mass-produced. Both Han and Tang mirrors are considered to be the most technically advanced. Bronze mirrors continued to remain popular up through the Song Dynasty, but then gradually lost their popularity and ceased to be produced after the arrival of Western mirrors during the Ming and Qing dynasties.
In Japan, a lot of bronze mirrors have been unearthed in the ruins of the tumulus period from Yayoi era. Mirror to be excavated, and Chinese cabbage mirror of imports from the continent, are classified it to HOSEI(仿製) mirror(made in Japan) domestic imitating the (law success). The types, rated chrysanthemum mirror (law Kakuki predicament) and the inner row Hanabunkyo (introvert Kyo Kamon) who excavated from Yayoi ruins of northern Kyushu, triangle edge to be excavated from the keyhole-shaped around the country as the center of the Yamato Kamijuukyo (Sankakubuchishinjukyo), and the like.
Yayoi period ( 300 BC to AD 300 in Japan)
Bronze mirror is the excavated goods that characterize the Yayoi era along with the bronze bell-shaped vessel, bronze mirrors, bronze bell-shaped vessel cultural sphere and the like have been discussed by the distribution.
Mid-term of the Yayoi era, in the northern part of Kyushu, the Western Han Dynasty mirror to jar coffins began to be congestion. Bronze mirror is prized as a treasure device, Han mirror after began to begin to congestion is to late, is Desa cast statements that I put a prayer to longevity, people with the mirror prosperity of longevity and descendants it was that is Yakusa. In addition, anyone rather than be able to own a bronze mirror, it has been limited to such influential people and the priest's. In the Sea of Genkai coastal areas in northern Kyushu, there is a jar coffin was congestion a large number of mirror of even 20 sheets Toka 30 sheets, etc. immediately Okamoto ruins and Mikumo ruins, is seen luxury of the king of the tomb. Customs that congestion a bronze mirror in the tomb, is also taken over by the tumulus era, has spread across the country.
Mirror as grave goods is, in the front during the ... late, was the so-called Han mirror or Han-type mirror, in the end-of-life ancient tomb is in Sui-Tang mirror. However, it is the only format name, it is not actually affected by the Sui and Tang.
Kofun Period ( AD 250 – 538 in Japan )
The excavated example of bronze mirror of Kofun period the previous year, 36 surface of the Tsubai Daizukayama tumulus, 34 surface of the Shinzan tumulus of Nara Koryo-cho, 34 surface of the black tomb [1], about 30 surface of Samita Takarazuka tumulus, Yamato Tenjinyama 23 surface of the tumulus, 22 surface of the Gotabi mountain ancient tomb of Osaka Habikino, 12 side of the purple Mountain tumulus, 30 surface of Heshan tumulus of Okayama Prefecture Bizen, 13 surface of Kurumazuka Bizen, Aichi Prefecture Inuyama of Higashino Palace ancient tomb there are 11 and the like face. This is seen as Wajin peculiar customs that fill with the dead to put a bronze mirror in a coffin. From Sakurai Chausuyama tumulus of Sakurai City, Nara Prefecture has been excavated a large number of pieces of bronze mirror, where the Nara Prefectural Kashiharakokogakukenkyusho was measured three-dimensional debris, it was restored to the 81-screen portion.
Bronze mirror as a faith subject
In Japan, the mirror has been the subject of Shinto faith. As those that appeared in Japanese mythology, there is such as one of Yata no Kagami and day image mirror, Sunday pike mirror of (the three sacred treasures), there is that enshrined in the company in the mirror as the object of worship.
Since the Heian period, was the subject of faith worship to the Buddha statue in the line carved "mirror image" (Kyosan) is actively produced in the mirror, this is "Kakahotoke" was fitted with a statue of a semi-meat carved in copper plate after (over It has evolved to Buddha)
For Shinto, bronze mirror is also a symbol of as a gift from God, it has been worshiped long in many of Japan's shrine.
In Europe, bronze mirrors from the Bronze Age have been discovered from various places, including Britain and Italy. A notable example includes the Birdlip mirror. Etruscan mirrors were produced from between the 6th and 2nd centuries BCE. Celtic mirrors in Britain were produced up until the Roman conquest.
See also[edit]
Media related to Bronze mirrors at Wikimedia Commons
- ^ Z. Y. Saad: The Excavations at Helwan. Art and Civilization in the First and Second Egyptian Dynasties, University of Oklahoma Press, Oklahoma 1969, p.54
- ^ Richard Corson: Fashions in Makeup: From Ancient to Modern Times, 1972, ISBN 0-7206-0431-1, p.32
Further reading[edit]
- B. Schweig: "Mirrors", Antiquity, Vol. 15 (1941), pp. 257–268
External links[edit]
|This article needs additional citations for verification. (August 2007) (Learn how and when to remove this template message)


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The B-52's (Audio Cassette)
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Track Listings
|1. Planet Claire
|2. 52 Girls
|3. Dance This Mess Around
|4. Rock Lobster
|5. Lava
|6. There's a Moon in the Sky (Called the Moon)
|7. Hero Worship
|8. 6060-842
|9. Downtown
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Product Description
The B-52's campy debut! Contains their signature hit Rock Lobster !
This record shook up the snoozing world of rock in 1979, becoming a truly classic disc, one full of landmark moments and heavy with possibilities. Most "real" rockers in the late '70s tried hard to ignore the Sex Pistols and the Clash, claiming the punk tumult was a merely a fad; but fun-loving types couldn't resist the magnificent hooks and grooves of the B-52's debut. They fell into the "new wave" while dancing their tushes off. The magnificent "Rock Lobster" remains unmatched in terms of its relentless, spastic power to move one's feet; ditto "52 Girls," with its nod to '60s trash rock. A Cramps-ish guitar grinds through "Lava," which features his-and-hers innuendo-laden lyrics. "I'm not no limburger!" goes one line from "Dance This Mess Around," but you just never question why. Brilliant. --Lorry Fleming --This text refers to the Audio CD edition.
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Opening with the memorable "Planet Claire," with its retro-rhythms, electronic pings, and truly off the wall lyrics, the band puts you on notice: it will be quite unlike anything you've heard before. And that holds true through virtually every cut. Of course, whether you like it or not is an entirely different matter: it can be difficult to relate to music made with such instruments as smoke-detectors, toy pianos, and a stripped down guitar-bass-drums combo, not to mention lyrics that often seem to be thrown together from the first rhyming words the band could think of. Quite a few people will find that a little of it goes a long way.
But it grows on you. It really does. "52 Girls," with Cindy Wilson and Kate Pierson spewing out female names very much like you'd recite state capitols in high school, is wickedly funny once you manage to tune into it--and when you move on to "Dance this Mess Around" you're hooked, plugged into Cindy and Kate's alternately strident, alternately harmonic vocals and Fred Schneider's unexpected rap-like interjections.
For all its weirdness, this is music designed to get you on your feet, and on draggy days when I don't quite feel up to the task I can drop this particular CD on the stereo and "dance this mess around" all the way to a spotless kitchen.Read more ›
It's still hard to define the music which is a fun blend of pop, quirky funk and experimental rock. In addition to the jerky arrangements, the innovative vocals are what made the mix so successful and distinctive. The male voice hovers between a singing and speaking style while the female vocals frame it with tight, urgent harmonies and shrieks. The closest comparison I can find of a similar band from the same era is The Flying Lizards, but they were much more obscure.
My favourite songs include the jerky Rock Lobster with its great hooks, the tuneful Planet Claire and the infectious Dance This Mess Around. Many of the tracks are good for the dancefloor too. Although not all the songs are up to the quality of the aforementioned hits, they're all innovative, funny and listenable. After all these years, this album still sounds unique.
There are a handful of B-52's anthologies on the market, but their late-blooming commercial success detracts from the brilliance of their debut. There isn't a weak track among the bunch. Beginning with the bizarre "Planet Claire," the listener goes on a wild journey that is steeped in the culture of 1950s science fiction movies, beehive hairdos, dance crazes, and joyful irreverence.
Musically, the band adopts much of the punk "do it yourself" attitude that prevailed during the time of the album's release. Bass guitars seem to fixate on one chord, rhythm guitars run up and down scales, and basic drum beats push the songs forward. Cindy Wilson and Kate Pierson's voices, which at first blush seem so wildly out of tune, blend in a manner that is sublimely beautiful. Fred Schneider's vocals, which recall Rex Harrison's talk/singing in the film version of "My Fair Lady," seem so natural in this setting that it's easy to find yourself singing along with him at any point.
Lyrically, the band explores territory that few have ever chanced. Name-checking Tina Louise and Jackie Onassis in "52 Girls" is unique to say the least, and including a reference to limburger cheese in a list of dances ("Dance This Mess Around") is a route that was never evident to Burt Bacharach.Read more ›
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les B`52 sont venus à montréal l`été dernier,mais je n`ai malheureusement les voir. Read morePublished on Feb. 25 2012 by mitche
What's that you say? You want party music. You wanna dance like a monk-funk mowgli, but you don't want to be seen to be a trend-hound, you don't want to leap aboard this... Read morePublished on Dec 30 2003 by Stanley B.
Looking for something fun? Look no further - the whole point of the B-52's is fun with a grove, something that will make you smile as you sing along, and make you just wanna... Read morePublished on Nov. 11 2003 by Damian P. Gadal
in the performing arts, originality is key, and the b-52's arethat in spades. there can neverbe another. thats it, end of story. Read morePublished on Oct. 12 2003
R.E.M. might be the most famous musical act to come out of the supposedly sleepy college town of Athens, Georgia, with the Indigo Girls being a close second, but the B-52's were... Read morePublished on July 22 2003 by Lawrance Bernabo


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There is no secret that Mississippi State has depth issues off the bench.
Stansbury searching for minutes
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Five-day Weather Forecast for Phoenix, AZ
One of Canada's largest marine mammals, the bowhead whale, was seen in the Cumberland Sound in eastern Canada.
Do NOT attempt this. Hong Kong locals risk their lives at the edge of a port during Typhoon Haima to snap some photos.
A slow-moving system of heavy rain and wind impacted much of central and eastern Massachusetts. But flooding may not be the only danger.
A tornado barreled through Santa Catarina, Brazil, and this man caught it on camera quickly approaching!
Many towns in Pennsylvania were impacted by the severe weather that thrashed through the state. Residents are recovering from the damage brought by it.
A new telescope is currently under construction. In a few years, it will succeed the Hubble Space Telescope.
This drone video shows the beauty of fall foliage at its peak in mid-October in New Hampshire.
After Sunday's blustery winds, another surge of cold air will move into the Northeast early this week.


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Women's Black Stardust Bracelet Size Medium 20cm
Swarovski Stardust bracelet. This must-have bracelet is perfect for mixing and matching with other bracelets for a trendy stacked look. It features a black nylon fishnet tube filled with tiny clear crystals. The easy-to-use magnetic closure shines in palladium-plated metal. Available in two sizes. Color: black


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realmagick.com The shrine of knowledge.
Wei Zhongxian
- 'I Try to Talk Less': A Conversation with Ai Weiwei and Liao Yiwu
- Liao: The Donglin Faction [a union between a rising merchant class and local landlords against the central government] involved opposition to the eunuch Wei Zhongxian. They knew that the Ming Court wanted to destroy them.
- The navigator protein
- Siying Qin, Hang Yin, Celi Yang, Yunfeng Dou, Zhongmin Liu, Peng Zhang, He Yu, Yulong Huang, Jing Feng, Junfeng Hao, Jia Hao, Lizong Deng, Xiyun Yan, Xiaoli Dong, Zhongxian Zhao, Taijiao Jiang, Hong-Wei Wang, Shu-Jin Luo and Can Xie, from the ...
- Movie Review: Brotherhood Of Blades (Xiu Chun Dao) from The New York Asian
- Brotherhood of Blades (Xiu Chun Dao 2014) is set in 1627, towards the end of the Ming Dynasty, when the young Chogzhen Emperor (Sherman Ye) decides to end the influence of all-powerful head of the Eastern Depot Secret Police Eunuch Wei Zhongxian ...
- Brotherhood of Blades
- When the teenage Chongzhen Emperor (Sherman Ye) takes over the throne from his late brother, he expels Chief Eunuch Wei Zhongxian (Chin Shih-chieh), who had held enormous power as head of the dreaded Eastern Depot secret police, and starts to ...
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text: Stay Smart at Our New Royse City - Rockwall Area Hotel Welcome to the Holiday Inn Express® hotel of Royse City, TX. Our property's premier location off Interstate 30, just 9 miles from Rockwall and about 30 miles from Dallas, is ideal for business and leisure travelers alike. Guests to our hotel's property near Rockwall are only five miles from Rockwall Technology Park and area businesses, including L3 Comcepts, EZ-FLO International, Graphics Microsystems, Owens-Illinois Plastics Group. Our Royse City, TX hotel's services include free Wi-Fi, as well as a 24-hour Business Center with copy, fax, PC and print resources. With these services and the help of our friendly staff, guests have all that they need to stay productive in Royse City, TX. Our hotel's leisure guests are happy to know that they are just five miles from Lake Ray Hubbard, Lake Tawakoni and Lake Lavon, making it easy to spend a day fishing, sailing or boating with the family. Other fun attractions include, Southern Juction, golf at Stone River or the harbor in the historic downtown Rockwall area, which our hotel is also near. No matter the reason you're visiting, this Holiday Inn Express® hotel's facility near Rockwall is a perfect pick. We're pleased to offer modern décor, a versatile location and great amenities, including a complimentary, hot breakfast bar, 24-hour Fitness Center and an outdoor pool. Stay Smart when you stay with us!


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The Internal 22x SATA DVD-Writer from Samsung is a high-speed internal DVD writer featuring smart, WriteMaster technology. With WriteMaster, burning discs has never been easier. It automatically detects the media type and writes the disc at the most optimal speed. Just insert the disc and click burn. It can burn both CDs and DVDs at speeds up to 48x and can be equally useful as a reliable, long-term backup solution.This DVD-writer features an aerodynamic enclosure which reduces heat for smooth, reliable operation and helps reduce noise. It even provides vibration control for high speed writing and tilts the objective lens when the disc isn't laying flat for ultimate reliability.
|Internal, half height SATA
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DVD+R 22X (29.7 MB/sec) write, 16X (21.6MB/sec) read
DVD+RW 8X (10.8MB/sec) write, 12X (16.2MB/sec) read
DVD+R DUAL 16X (21.6MB/sec) write, 12X (16.2MB/sec) read
DVD-R DUAL 12X (16.2MB/sec) write, 12X (16.2MB/sec) read
DVD-R 22X(29.7 MB/sec) write, 12X (16.2MB/sec) read
DVD-RW 8X (10.8MB/sec) write, 12X (16.2MB/sec) read
DVD-ROM (Single) - 16X (21.6MB/sec) read
DVD-ROM (Dual) - 12X (16.2MB/sec) read
CD-ROM - 48X (7.2MB/sec) read
CD-R 48X (7.2MB/sec) write, 40X (6.0MB/sec) read
US-RW 24X (3.6MB/sec) write, 40X (6.0MB/sec) read
HS-RW 10X (1.5MB/sec) write, 40X (6.0MB/sec) read
CD-RW 4X (0.6MB/sec) write, 40X (6.0MB/sec) read
DVD-RAM 12X (16.2MB/sec) write, 12X (16.2MB/sec) read
|Data Transfer Mode
|SATA 1.5Gbps
|Buffer Memory
|Horizontal or vertical
|Disc Formats
Read: MASTERED DISC, CD-R, CD-RW, DVD-ROM, DVD-R 3.95GB, DVD-R 4.7GB Authoring, DVD-R 4.7GB General, DVD-RW 4.7GB, DVD+R 4.7GB, DVD+R 8.5GB(Double-layer), DVD+RW 4.7GB, DVD-RAM 4.7GB/2.6GB
Write: DVD 4.7GB(DVD±R, DVD±RW, DVD-RAM), Double Layer±R, CD-R, CD-RW
CD: CD-DA, CD-ROM, MIXED-CD, CD-ROM XA, ENHANCED-CD, CD-EXTRA/CD+, Photo-CD, VIDEO-CD, CD-TEXT, CD-G, Multi-Session
DVD: DVD-RAM, DVD-ROM, DVD-VIDEO, Multi-Session(Read/Write), Multi-Border(Read)
CD-R/RW: DAO, TAO, SAO, Packet Write(RW)
DVD+R/RW: Sequential, Random(RW)
DVD-R/RW: Incremental, DAO, Restricted Overwrite(RW)
DVD-RAM: Random
|Lead free
|Not supported
|Dimensions (WxDxH)
|With bezel: 5.83 x 6.69 x 1.65" (14.82 x 17 x 4.2 cm)
|Not specified by manufacturer


text:
I can't get enough of these blood orange Italian sodas, they're refreshing, easy, and family-friendly!
In middle school my friends I became obsessed with italian sodas. We got them almost every day at school, and raspberry was my favorite flavor. And then we moved on to some other obsession, and I completely forgot all about italian sodas.
Until this weekend, 20 years (!) later, when I got hooked all over again.
Except this time I made them myself with homemade blood orange syrup. Layered with ice, sparkling water and a little creamy half and half, it's a very fun and refreshing beverage.
Blood oranges are in season right now and are definitely worth seeking out. They're both sweet and tart, and I love the unusual color. But you can easily change up the recipe below with any citrus you like— lemons, clementines, grapefruit, etc.
I've been drinking these italian sodas all weekend long, and I don't intend to stop!
- Blood orange simple syrup (recipe below)
- Ice
- Sparkling or seltzer water
- Half and half
- Zest from 2 blood oranges
- 1 cup (237 ml) freshly squeeze blood oranges
- ¾ cup (150 grams) granulated sugar
- In a small saucepan, bring the zest, blood orange juice and sugar to a boil, stirring occasionally to dissolve the sugar. Remove from heat and let cool to room temperature. Strain and chill in the fridge until ready to use.
- In a highball glass, add approximately ¼ cup of blood orange syrup. Fill glass most of the way with ice and then sparkling or seltzer water. Top with a few splashes of half and half. Stir and enjoy!
Some of my blogging friends and I are taking on the challenge to eat seasonally. Check out Vintage Mixer's guide to what's in season this month and join us, won't you?
Roasted Cauliflower with Lemon Vinaigrette by Bless this Mess
Quinoa Salad with Grapefruit and Golden Beets by Cafe Johnsonia
Brussels Sprout Thai Pizza by Climbing Grier Mountain
Meyer Lemon and Zahatar Seasoning Salt by Project Domestication
Broccoli and Shiitake Mushrooms With or Without Soba Noodles by Foodie Crush
Parmesan Parsnip Fries by Well Plated
Acorn Squash Bread with Seeds and Nuts by Vintage Mixer
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7 Responses to Blood Orange Italian Sodas
I love how easy it is to make yet it looks so fancy!
xo, Elisa
I just flipping love these! So delicious!!
Carrie @ Bakeaholic Mama says:
I love almost any Italian soda, but especially orange! This looks amazing.
Liz @ Floating Kitchen says:
This is really beautiful, Annalise! I've got some blood oranges sitting in my fridge right now and they are being earmarked for this!
Megan {Country Cleaver} says:
I absolutely adore Italian sodas, too! And the color of these – dreamy!
Sues says:
Is there anything prettier than a blood orange?? These look glorious!!
Chels says:
This looks so refreshing!
Leave a Reply Cancel reply
about meHi, I'm Annalise and I love to bake! Welcome to my blog, where you'll find recipes, baking tips and tricks, and more.
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Kitsap County looks for another $4.7 million in cuts
Faced with declining revenues and a potential $4.7 million in budget cuts next year, the Kitsap County commissioners are grappling with the question of where the budget ax will swing next.
"The Board of Commissioners will ask that appointed departments and separately elected offices prepare and present their budget requests on a program basis," said Commissioner Charlotte Garido. "This programmatic analysis will involve measuring a program's effectiveness, overall value, alignment with the priorities of citizens, level of service provided, and response to constitutional mandates.
"The county's general fund has seen a continual decline of revenues over the last several years," she said, "and that, combined with the 1 percent property tax cap, has required substantial corresponding reductions.
"These reductions have been tough to make," Garrido said, "though most have been one-time cuts or have taken place at the fringes and the county can no longer afford to make incremental changes.The board is faced with making reductions in service levels and perhaps eliminating some programs altogether based on an objective analysis of priorities."
"This is the fourth consecutive year of cuts," said Commissioner Steve Bauer. "The easy ones are past, and now we will have to look carefully at all options."
In addition to the $4.7 million in potential budget cuts for 2011, the county has communicated a $610,000 budget deficit for this year. This raises the question of a balanced budget being achieved.
"These numbers represent an order of magnitude which may be difficult for citizens to grasp," said Garrido. "Continued drops in revenue at this level require a significant effort on the part of departments and offices to reorganize and reduce services in a much more visible way in 2011.
"Past deficits have been absorbed through incremental reductions in programs," she said, "while striving to continue at the same level of service with less staff and funding. A balanced budget for 2011 will be attainable only through major changes in programs and with service level reductions."
"State law requires a balanced budget," said Bauer. "The budget will be balanced, but the cost in services will likely be high.
"Both numbers are discouraging," he said, "given all the cuts that have had to be made in the last three years."
Decreased property tax revenues and their impact on the current and future budgets are in part being blamed for the budget deficit.
"Property taxes make up 34 percent of total anticipated revenues in the general fund ($28.3 million out of $82.5 million) for the 2010 budget," said Garrido. "The preliminary estimates for 2011 are holding at the 34 percent of total budget mark as well ($27.5 million out of $79.5 million), but our staff forecasts a 2010 shortfall in property tax receipts (when compared to the budget) of $938,424, or a little more than 3 percent less than anticipated.
An additional $1 million in delinquencies has been included in the property tax revenue estimate for the 2011 budget-building process.
"Prior to enactment of the property tax limitation, the county managed its programs and had built a $14 million reserve fund," said Bauer. "The last time the county approached the voters for a property tax for general operation purposes (other than 2002), was over 30 years ago.
"The current recession would still have hurt financially, but even before the recession the county was faced with an annual shortfall of $1.5 to $2 million per year," he said. "For several years, the board balanced by spending reserves.
"In 2008," Bauer said, "we balanced the budget without reserves for the first time in several years by making substantial cuts in programs. Once the recession is over, the county will still have to deal with the effects of the 1 percent limitation by either cutting programs or increasing revenues or both.
"The problem," he said, "is a constant series of budget cuts. That's not a way to sustain an organization or the services the public relies on."
Discussions regarding possible solutions have compelled the county to take a hard look at cutting longevity pay, omitting benefit increases and potentially reducing them and getting prepared for another round of layoffs.
"Kitsap County has to take a hard look at all aspects of the budget," Garrido said. "Longevity as a concept has been discussed by the board and the separately elected officials. However, the issue of reducing or eliminating longevity pay is a matter of collective bargaining and differs from one labor contract to the next.
"Through the collective bargaining process," she said, "negotiators will be looking at all economic components of the contracts, including longevity pay and other benefits with the hopes of reaching an agreement with the labor unions that preserve jobs and compensation, while living within the confines of the revenues available.
"It is the goal of the board," Garrido said, "to avoid balancing the budget solely on the backs of the employees, and they have pledged to do their part by pursuing various revenue enhancements. Even in the best of circumstances, though, it is likely that cuts of the magnitude required for 2011 will at least partially be implemented through some reduction in force."
"The county has looked at all of these options," Bauer said. "We have collective bargaining agreements and many of these options must be bargained with our unions.
"The unions have already made a number of concessions," he said. "We're also looking at ways to manage future compensation increases better to try to bring compensation growth closer to revenue growth. Even when that's done, the county will still need to seek new revenues in order to preserve services.
"The other piece the county must consider," Bauer said, "is future incorporations and annexations of areas we currently serve with the corresponding loss of revenues."
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About Cool Runnings
Featuring grills, light meals and Island style cuisine, Cool Runnings sets the pace for a laid back vibe.
With a delicious munchies menu and good Jamaican sounds, diners peruse the full restaurant menu brimming with seasonal spreads.
Choose from island style curries, Jamaican Babylon Burgers; stir fries, jerk and Creole dishes as well as lots of basket dishes to share between friends.
Dine in Island style vibe around a bonfire beer garden and rustic bar sampling exotic cuisine and seasonal specials at Cool Runnings in Bloubosrand.
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Cuisine Other:
Grills, Light Meals
Lunch, Dinner
Restaurants in Johannesburg and surrounds
Cool Runnings Map
Cool Runnings is 10.4km from the centre of Johannesburg and surrounds , the nearest airport 10km (Lanseria International Airport).
*Distances are shown as the crow flies and not necessarily the actual travelling
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Other restaurants near Johannesburg and surrounds
The decors whispers subtle Urban Chic infused with Boudoir classics that invite elite crowds to...
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text: Director's Forum: A Blog from USPTO's Leadership (Comments) http://www.uspto.gov/blog/director/feed/comments/atom 2016-10-27T03:58:29-04:00 Apache Roller (incubating) http://www.uspto.gov/blog/director/entry/uspto_launches_two_new_online#comment-1462394637000 Re: USPTO Launches Two New Online Fee Payment Tools Bill Wiltrack 2016-05-04T16:43:57-04:00 2016-05-04T16:43:57-04:00 Hello, First time I visited your site. I can't seem to find exactly where the dollar rates for a provisional patent are found. http://www.uspto.gov/blog/director/entry/uspto_submits_its_fiscal_year1#comment-1461028299000 Re: USPTO Submits its Fiscal Year 2017 Congressional Budget Justification matt 2016-04-18T21:11:39-04:00 2016-04-18T21:11:39-04:00 $3.3 billion in fee revenue seems like an incredible amount of money? This is good news however as it means that the US is progressing well which is actually, believe it or not, good for the rest of the world. http://www.uspto.gov/blog/director/entry/uspto_launches_two_new_online#comment-1460391773000 Re: USPTO Launches Two New Online Fee Payment Tools SHOOK, HARDY & BACON L.L.P. 2016-04-11T12:22:53-04:00 2016-04-11T12:22:53-04:00 Are these new procedures for Deposit Account payments and Maintenance Fee payments only? Not the usual credit card payments? Thanks Sandra Sutton http://www.uspto.gov/blog/director/entry/ptab_issues_final_rules_for#comment-1459455364000 Re: PTAB Issues Final Rules for Improved Proceedings American Inventor 2016-03-31T16:16:04-04:00 2016-03-31T16:16:04-04:00 BRI should be eliminated altogether. The claim construction standard used in district courts would be much more consistent with the process in which patents are granted in the first place. http://www.uspto.gov/blog/director/entry/improvements_in_measuring_patent_quality#comment-1459452729000 Re: Improvements in Measuring Patent Quality Metrics USPTO 2016-03-31T15:32:09-04:00 2016-03-31T15:32:09-04:00 Aida, Thanks for your question. Yes, we will webcast the full day of the symposium, and will be posting further information about this on the USPTO website soon. http://www.uspto.gov/blog/director/entry/improvements_in_measuring_patent_quality#comment-1459440858000 Re: Improvements in Measuring Patent Quality Metrics Aida Dolotbaeva 2016-03-31T12:14:18-04:00 2016-03-31T12:14:18-04:00 Hello, will the Patent Community Symposium on Wednesday, April 27, be webcast? Thank you Aida Dolotbaeva http://www.uspto.gov/blog/director/entry/leadership_in_all_uspto_regional#comment-1454153384000 Re: Leadership in All USPTO Regional Offices Godlove 2016-01-30T06:29:44-05:00 2016-01-30T06:29:44-05:00 Congratulation Molly Kocialski I hope you will make a fine director. http://www.uspto.gov/blog/director/entry/leadership_in_all_uspto_regional#comment-1454006607000 Re: Leadership in All USPTO Regional Offices https://www.thedebtconsolidationreviews.com 2016-01-28T13:43:27-05:00 2016-01-28T13:43:27-05:00 I think what USPTO regional offices put tools into the hands of individuals who need assistance at every step of the business lifecycle... whether it is possible to join your teams? -:) http://www.uspto.gov/blog/director/entry/a_historic_moment_for_the#comment-1453954693000 Re: A Historic Moment for the USPTO and Innovators Everywhere zaenudin 2016-01-27T23:18:13-05:00 2016-01-27T23:18:13-05:00 your blog is one of several types , I am very happy with the way you set the topic . http://www.uspto.gov/blog/director/entry/a_historic_moment_for_the#comment-1452010184000 Re: A Historic Moment for the USPTO and Innovators Everywhere USPTO 2016-01-05T11:09:44-05:00 2016-01-05T11:09:44-05:00 Preeti, we are planning to post the next vacancy for Dallas around mid May for a mid-September class of entry-level examiners. Please monitor USAJobs.gov (keywords: USPTO Dallas) as well as LinkedIn and @USPTOJobs on Twitter for news of the job opening. http://www.uspto.gov/blog/director/entry/power_and_systems_update#comment-1451813658000 Re: Power and Systems Update JOHN ALTY 2016-01-03T04:34:18-05:00 2016-01-03T04:34:18-05:00 Dear Russell Happy New year and best wishes to USPTO from the UK IPO. Congratulations on the hard work and dedication of your teams in getting things back up and running. Early on in my time as CEO of the UK IPO we suffered a DDOS attack which meant we had to take down all our external systems for a few days, which was a little stressful to say the least. I hope you and your team get some rest over the New Year. best wishes John Alty http://www.uspto.gov/blog/director/entry/a_historic_moment_for_the#comment-1451539185000 Re: A Historic Moment for the USPTO and Innovators Everywhere Bernadette Anderson 2015-12-31T00:19:45-05:00 2015-12-31T00:19:45-05:00 Congratulations to Hope Shimabuku on becoming the first Director of the Texas Regional Office. http://www.uspto.gov/blog/director/entry/enhanced_patent_quality_initiative_moving#comment-1451476622000 Re: Enhanced Patent Quality Initiative: Moving Forward Sophia 2015-12-30T06:57:02-05:00 2015-12-30T06:57:02-05:00 It is certainly very important to ensure quality in such processes where it really counts. I believe that the processes you have taken to try to improve outcomes are necessary and it sounds like you are already seeing results. Good news and thank you for sharing details of this collaboration. http://www.uspto.gov/blog/director/entry/a_historic_moment_for_the#comment-1450219024000 Re: A Historic Moment for the USPTO and Innovators Everywhere Preeti Narayan 2015-12-15T17:37:04-05:00 2015-12-15T17:37:04-05:00 Thank you for your article. This is exciting news for us Dallas residents. When do you expect the next round of hiring for Patent examiners in Dallas will be? I didn't know and hence didn't apply the first time. http://www.uspto.gov/blog/director/entry/a_historic_moment_for_the#comment-1449912274000 Re: A Historic Moment for the USPTO and Innovators Everywhere Danny Gow 2015-12-12T04:24:34-05:00 2015-12-12T04:24:34-05:00 Congratulations Hope! All the best, Danny Gow Director, R&D TT Electronics, Carrollton TX http://www.uspto.gov/blog/director/entry/enhanced_patent_quality_initiative_moving#comment-1446840099000 Re: Enhanced Patent Quality Initiative: Moving Forward Victor A Rivas 2015-11-06T15:01:39-05:00 2015-11-06T15:01:39-05:00 First Thank you for this needed programs & assistance to inventors but also to industry to look for common ground of progress. I like USPTO's format for us no lawyers to understand and be able to seek legal counsel to next level once we do our homework about USPTO programs and initiatives. As far as The USPTO' s work and innovative approach in today IP matters Our taxes are well invested. The San Jose USPTO office great move That's Cool it saves ??And ��nowadays ideas ��move ?? Fast Nanotechnology Inventor http://www.uspto.gov/blog/director/entry/icons_for_intellectual_property_concepts#comment-1446207921000 Re: Icons for Intellectual Property Concepts Unveiled Sophia 2015-10-30T08:25:21-04:00 2015-10-30T08:25:21-04:00 This is something that I wouldn't have considered important before, but the article gives good information about why these icons are crucial. I think the icons are very clear, effective, and artistic. They represent excellent ways to produce abstract concepts in pictorial form. It was a good idea to involve members of the public in their creation. http://www.uspto.gov/blog/director/entry/joint_communique_between_u_s#comment-1439573028000 Re: Joint Communique Between U.S. and Brazil on Patent Work Sharing Sergio F Chacon 2015-08-14T13:23:48-04:00 2015-08-14T13:23:48-04:00 U. S. National Phase in Brazil Protocol Number: DE RS 016060013063 Filed: Filing date: September 08TH, 2006 Priorities claimed: US 10/805,117 of 19.13.2004 Dear Sirs: It is great news to know that the subject of backlogs has been discussed. What has come out of the joint communication? I cite above one (of many) applications filed in 2006, for which every fee possible has been paid and which still awaits examination. If INPI in Brazil wishes to be taken serious, they will have to do substantially better. http://www.uspto.gov/blog/director/entry/addressing_ip_rights_issues_in#comment-1438227574000 Re: Addressing IP Rights Issues in China susanrey 2015-07-29T23:39:34-04:00 2015-07-29T23:39:34-04:00 Your trip is very meaningful and also an informative article, which informs me that the China is trying their best to pave the way for their own development. This is also a big opportunity for America and other countries to have a cooperation relationship with China. just like environment, economy and other kind of cooperation is very benefit for us. the IP is also a big problem in our country. http://www.uspto.gov/blog/director/entry/addressing_ip_rights_issues_in#comment-1437549539000 Re: Addressing IP Rights Issues in China Christian Browne 2015-07-22T03:18:59-04:00 2015-07-22T03:18:59-04:00 Its good to see that the USPTO is trying to address these issues with China. Historically China has been the manufacturer of products incorporating IP developed outside China and as such it has not been in China's interest to develop a robust IP registration and enforcement protocol. One hopes that as China moves away from outsourced manufacturing to innovation and development of IP, it will value a robust registration and enforcement regime in order to protect IP developed in China. This hopefully will have spin-off benefits for all other countries. The aim of any long term strategy must be to get China to sign up to and comply with the various international IP protocols. Christian Browne http://www.summerfieldbrowne.com http://www.uspto.gov/blog/director/entry/farewell_from_uspto_s_commissioner#comment-1435520119000 Re: Farewell from USPTO's Commissioner for Patents Bob Spaulding 2015-06-28T15:35:19-04:00 2015-06-28T15:35:19-04:00 Good Job Peggy! I wish you well! I was hoping you would be the one examining my idea... http://www.uspto.gov/blog/director/entry/uspto_launches_enhanced_patent_quality#comment-1427004780000 Re: USPTO Launches Enhanced Patent Quality Initiative William T. Fryer III 2015-03-22T02:13:00-04:00 2015-03-22T02:13:00-04:00 To: Director Lee. I urge the PTO to make the Patent Quality session event videos and papers available on the Internet, as they do for most PTO Roundtables, as promptly as possible. I, and a large group of the ABA, IP Section members, will be attending its annual CLE in Maryland at the same time as the PTO Patent Quality event. It is an unfortunate conflict. I request that adequate time be allowed to digest the event results, for the Section leadership, its members and others to respond after the Patent Quality Event. William T. Fryer III Professor Emeritus, University of Baltimore School of Law, Patent Attorney http://www.uspto.gov/blog/director/entry/user_feedback_plays_key_role#comment-1423233757000 Re: User Feedback Plays Key Role in New USPTO Website Randall Svihla 2015-02-06T09:42:37-05:00 2015-02-06T09:42:37-05:00 Why is all of the text on the new website gray? It's hard to read. Why not just use black? It's easier to read. I liked the look of the old website better, and knew where to find everything I needed. Now I have to relearn where to find everything. Would it be possible to go back to the old website? Thank you. http://www.uspto.gov/blog/director/entry/user_feedback_plays_key_role#comment-1422920555000 Re: User Feedback Plays Key Role in New USPTO Website Steve 2015-02-02T18:42:35-05:00 2015-02-02T18:42:35-05:00 Love the new site, the kids site , and the blog - thanks! http://www.uspto.gov/blog/director/entry/patent_pro_bono_program_expansion#comment-1418942543000 Re: Patent Pro Bono Program Expansion to Benefit Inventors Nationwide Ramasamy Rangan 2014-12-18T17:42:23-05:00 2014-12-18T17:42:23-05:00 I am a USPTO agent based in Kansas. I am interested in doing some probono work. But as I am not a member of federal bar ,I am not able to offer my services. Is the any thing I can do to get USPTO probono work established in Kansas. http://www.uspto.gov/blog/director/entry/update_on_uspto_satellite_offices#comment-1417719968000 Re: Update on USPTO Satellite Offices junior Moananu 2014-12-04T14:06:08-05:00 2014-12-04T14:06:08-05:00 Please open a satellite office in Honolulu Hawaii. That office will serve the pacific region which includes Guam and American Samoa. The current use of the Hawaii State Library for patent searches and filing is really inefficient. Thank you. http://www.uspto.gov/blog/director/entry/uspto_establishes_special_examination_unit#comment-1417235560000 Re: USPTO Establishes Special Examination Unit for Pro Se Applicants Warren Nelson 2014-11-28T23:32:40-05:00 2014-11-28T23:32:40-05:00 how much is the patent and issue fee for pro se applicants? http://www.uspto.gov/blog/director/entry/patent_pro_bono_program_expansion#comment-1416456297000 Re: Patent Pro Bono Program Expansion to Benefit Inventors Nationwide partoftheartrealitytv 2014-11-19T23:04:57-05:00 2014-11-19T23:04:57-05:00 This program should provise a contested service to the following: http://www.uspto.gov/aia_implementation/20120113-ippr_report.pdf http://www.uspto.gov/blog/director/entry/patent_pro_bono_program_expansion#comment-1416425975000 Re: Patent Pro Bono Program Expansion to Benefit Inventors Nationwide Bruce Burdick 2014-11-19T14:39:35-05:00 2014-11-19T14:39:35-05:00 I applaud the Deputy Under Secretary for committing the Administration to the goal "to balance the playing field for all entrepreneurs looking to innovate." I wish actions matched words. When I started practice 40 years ago, the filing fee was $35, issue fees were low, no maintenance fees, applications not published, patents more respected, and enforcement simpler and much less expensive. In short a small inventor had a chance. Today, you surely know that patents are mostly a "rich man's" tool. 14 pro bono patents out of over 8,000,000 is not even a pittance, but I applaud the start. I recall being instructed in law school "As a patent attorney, you must charge a reasonable fee or you'll go broke or get fired." Law firms have billable hour quotas, so pro bono cases get forced on reluctant junior associates. Frankly, the Government must fund this to get decent participation and decent quality. Right now it's an unfunded mandate you seek to impose on patent attorneys. http://www.uspto.gov/blog/director/entry/roundtables_engage_the_public_on#comment-1413415032000 Re: Roundtables Engage the Public on Digital Copyright Policy Stanley Brick 2014-10-15T19:17:12-04:00 2014-10-15T19:17:12-04:00 Big business takes what artist make. Copyright is dead to the micro small business.


text:
Want to make sure that your "favorite" jQuery bug is fixed in time for the upcoming 1.4 release? Then tell the jQuery dev team using the below form.
Category Archives: Uncategorized
2009 jQuery Halloween Pumpkin
In a repeat of last year's phenominal jQuery pumpkin Christopher Pickert is back with a brand new jQuery 1.3-using pumpkin that's sure to frighten visitors:
Thanks again to Christopher for this great creation.
jQuery Summit – Nov. 19th
Environments for Humans is running a one-day, online conference focusing on jQuery. The conference will be on November 19th and will feature a number of prominent members of the jQuery community, including members of the jQuery team.
The following talks are slated for the jQuery Summit:
- The State of jQuery – John Resig
- Web Interface Essentials – Marc Grabanski
- RIAs: Building for the Desktop with the Web – Jonathan Snook
- Rich Interactivity, Simplified, with jQuery UI – Richard Worth
- Refactoring jQuery – Jonathan Sharp
- JavaScript for Designers – David McFarland
- Building Robust jQuery Plugins – Jörn Zaefferer
- jQuery Anti-Patterns for Performance & Compression – Paul Irish
While a number of these talks are reprisals from the recent jQuery conference, this event is not being run by the jQuery project. That being said, it looks like it's going to be a lot of fun, and we encourage those that missed the conference in September to check it out.
All attendees will be receiving a free copy of the upcoming jQuery Cookbook, from O'Reilly. Additionally a number of prizes will be given away to attendees (books, DVDs, etc.).
Register for the jQuery Summit
There is a ticket discount in effect until October 30th. Additionally, if you register and use the discount code JQRYRESIGJ you'll save an extra 10% off the overall price. A portion of the proceeds will be coming back to help fund the project.
code.jquery.com Redirected to Google Ajax APIs
Starting at 10PM MT on August 20th, code.jquery.com will start redirecting (301) to ajax.googleapis.com [http://code.google.com/apis/ajaxlibs/documentation/index.html#jquery].
Immediate Impact:
- None
- Redirection will occur using 301 "Permanent Moved"
- Packed version will be replaced with minified version
Long Term:
- Migrate any sites using code.jquery.com to Google's AJAX Libraries API
Full documentation of Google's Ajax API are available at http://code.google.com/apis/ajaxlibs/documentation/index.html#jquery. Continue reading
Fall 2009 jQuery Talks
Reminder: While the upcoming jQuery Conference is already sold out, we're still looking for some excellent talks. We're accepting talk proposals until the 15th. If your talk is accepted your ticket fee will be waived.
Even if you can't make the jQuery Conference, though, there are a number of opportunities to meet members of the jQuery team, hear talks about jQuery, or generally mingle with other jQuery users coming up in the next couple months. If you happen to know of any other talks or events please comment below and we'll add them.
- Workshop: Conquering jQuery with Karl Swedberg
August 19th – 21st – Grand Rapids, MI
- User Group: ALT.NET: jQuery UI with Richard Worth
August 26th – Washington, D.C.
- Conference: Epicenter
August 26th – 28th – Ireland
- Meetup: North Carolina jQuery Camp
September 19th – Durham, NC
- Workshop: jQuery Fundamentals
September 25th – 26th – Carrboro, NC
- Conference: Stack Overflow Dev Days
October 7th – November 2nd – Various Locations
- Conference: Fronteers 2009
November 5th – 6th – Amsterdam
- Conference: JSConf.eu
November 7th – 8th
- Workshop: How to use jQuery to enhance your web design with Karl Swedberg
November 16th – New York, NY
- Conference: Full Frontal 2009
November 20th – Brighton, UK
- Conference: Rich Web Experience – Richard Worth
December 1st – 4th – Orlando, FL
jQuery Conference 2009: Registration Open
Registration for the 2009 jQuery Conference is now open!
Register here:
More information about the conference: Dates and Venue.
The agenda is still being worked on and will be announced shortly. It's fully expected that the conference will sell out again (as it has every year, so far) so if you're interested in coming please sign up sooner rather than later!
jQuery Conference 2009: Dates and Venue
Good news everybody! The dates and venue for this year's jQuery Conference have been determined.
The conference will be held September 12th and 13th at Microsoft Cambridge in Boston, MA.
This will be a 2 day conference with multiple tracks on each day. We're in the process of planning out the schedule, talking with speakers, and setting up the conference web site.
Watch the jQuery blog or jQuery Twitter feed for notification when registration opens.
While this venue is larger than those that we've had in the past (Harvard Law School in '07 and the MIT Stata Center in '08) we do expect to sell out all the available seats, as has happened every year so far. That being said, the venue is quite incredible, easily one of the best spaces available for a conference:
A brief synopsis of some of the content that you'll be able to expect:
The annual conference of jQuery users and developers. There will be talks on jQuery, jQuery UI, plugins, complex application development, and more – all from the top jQuery developers. Case studies from some of the leading users of jQuery will be included along with a 3 hour tutorial for those just getting started.
You can see the schedules from past jQuery conferences here: 2008, 2007. There will be a nominal fee (likely around $100-$150) to help us cover to cost of food for both days and shirts.
Looking forward to seeing everyone in Boston this fall!
Note: If you are interested in sponsoring the conference, please contact John Resig.
Update: There have been a lot of questions asking if there will be a conference on the west coast (San Francisco) or in Europe. While we don't have any immediate plans to hold conferences in those locations, this year, we would like to hold them in the future. In the meantime I recommend checking out Full Frontal (UK, November) and Fronteers (Amsterdam, November) – both of which should shape up to be excellent JavaScript conferences.
Update: Thanks to Jeff for adding the event to Upcoming.
jQuery UI 1.6rc6: Help us test!
jQuery UI 1.6rc6 is available.
Download jQuery UI 1.6rc6
You can download the entire development bundle directly at
This includes a default theme, as well as all the test and demo files. Or you can create a customized download of individual components
and a custom theme at
This is the final step before releasing 1.6 final tomorrow (Saturday night). Since we only have two days, we really need you help us test if there are no major blockers left we might have overseen. Please create a ticket for any issue you find on the jQuery UI bug tracker:
http://dev.jqueryui.com/ (note: requires registration)
and send a note for discussion on the jQuery UI Development mailing list as well:
Thanks everyone, prepare for a great weekend!
jQuery Meetup in San Francisco
There are a few jQuery guys in San Francisco this week and we thought it'd be fun to have a meetup. John Resig (Creator of jQuery), Rey Bango (Head of jQuery Evangelism Team) and Yehuda Katz (Rails Core Contributor, jQuery Team Member) will all be meeting up tomorrow night (the 29th) if you want to say 'hi'.
More information can be found on the Upcoming.org site for the event – feel free to add yourself if you're interested in coming:
jQuery 1.3.1 Released
Welcome Digg users! You may be interested in the full jQuery 1.3 release, which just happened on the 14th. Enjoy!
This is a bug fix release for jQuery 1.3. You can view the full list of what was fixed on the bug tracker.
There are no significant changes in 1.3.1 from 1.3 other than straight bug fixes. If you are still using jQuery 1.2.6, and looking to upgrade, please upgrade directly to this release.
- jQuery Minified (18kb with Gzipping)
- jQuery Regular (114kb)
A copy of jQuery 1.3.1 is also available on Google's CDN (feel free to copy the URL directly into your site):
If you wish to checkout the full release from the Subversion repository, you can do so by following the following instructions and checking out the source from the following location:
svn co http://jqueryjs.googlecode.com/svn/tags/1.3.1
A couple quick housekeeping notes:
Some noted in the release notes for 1.3 that we missed testing on Firefox 2, even though we still support it. This was a mistake on our part: We still support Firefox 2 and test on it prior to releases. You can see the full test suite run below.
It was also noted that Safari 2 didn't show up in the list of browsers that we tested against prior to the 1.3 release. This is correct – we are phasing out support for Safari 2 in jQuery. Considering that Safari 2 shows no appreciable market share and has been superseded by 3 separate Safari releases (3.0, 3.1, and 3.2) we no longer see a need for significant testing against that release.
Finally, a few users noticed that we no longer provide a "packed" version of jQuery (a version of jQuery run through Dean Edwards' Packer with Base62 encoding turned on). We did this for a couple reasons:
- Packed scripts are significantly harder to debug (even harder than minifed scripts).
- Packed scripts aren't able to run on all platforms without issue (such as Adobe AIR and Caja-capable environments).
- But most importantly: Packed scripts are slower for the user than what you would get from using just minification. This may seem counter-intuitive since a packed script's file size is smaller than a minified script but the final load time ends up being much higher (due to the decompression step it must go through). We have some data regarding the loading performance of minified scripts vs. packed scripts, for those that are interested.
The minifed copy of jQuery that we provide, run through the YUI Compressor, should be the optimal form of jQuery to use in a production environment (served using gzipping, if possible).


text:
FOXBOROUGH, Mass. -- The following players were not spotted in warm-ups for tonight's game against the Saints, an indication that they will not play. There are no changes from the list of players not expected to play, posted earlier today.
LB Tracy White
T Kyle Hix
G Dustin Waldron
T Kyle Hill
WR Deion Branch
TE Daniel Fells
TE Jake Ballard
DT Myron Pryor
DT Ron Brace


text:
|Publication number
|Publication type
|Application number
|Publication date
|Jul 18, 2006
|Filing date
|Sep 25, 2003
|Priority date
|Dec 28, 2000
|Fee status
|Also published as
|Publication number
|Thomas M. Soukup, Stephen Sundquist, Roger Dahl, Gregory A. Boser
|Original Assignee
|Medtronic, Inc.
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (26), Referenced by (16), Classifications (6), Legal Events (3)
|External Links: USPTO, USPTO Assignment, Espacenet
This Application is a divisional of Ser. No. 09/827,103, now U.S. Pat. No. 6,704,604, filed Apr. 5, 2001.
The present invention relates generally to implantable medical devices; and more particular, relates to implantable devices that include an exterior structure to selectively promote tissue ingrowth.
Transvenous cardioversion and defibrillation leads typically employ cardioversion or defibrillation electrodes taking the form of elongated metal coils. These coils may be applied to the exterior surface of the lead body, as disclosed in U.S. Pat. No. 4,934,049 issued to Kiekhafer et al.
One problem associated with defibrillation coils of the type discussed in the '049 patent involves the occurrence of tissue in-growth around the coil structure of the electrode. This is particularly true when the coil electrode is formed around the lead body so as to create an enlarged profile at the location of the coil as compared to the rest of the lead body. Tissue attachment that occurs proximal to the electrode structure makes it difficult to extract distal end of the lead, including the enlarged coil.
One way to reduce the problem of tissue in-growth involves providing defibrillation coils that are isodiametric with respect to the lead body. Such isodiametric electrode coils may be molded into the electrode body or the coils may be machined to provide a flush surface. This is described in U.S. Pat. No. 4,161,952, issued to Kinney et al. Similarly, U.S. Pat. No. 5,957,970 to Shoberg discloses an isodiametric defibrillation lead manufactured by removing a portion of an extruded tubular lead body in the region of the coil so that the electrode is flush with the surface of the lead. The 6944 Model lead commercially available from the Medtronic Corporation provides an isodiametric lead of this design.
Although isodiametric coil electrodes reduce problems associated with extracting an enlarged lead portion from ingrown tissue, other problems still exist related to ingrowth. For example, tissue commonly attaches around the coils of a defibrillation electrode, further increasing the difficulty associated with lead extraction.
Various methods have been attempted to overcome the problems associated with tissue in-growth around coil electrodes. One solution disclosed in the '049 patent referenced above involves injecting silicone rubber into the spaces between the individual coils of an electrode. The resulting thin coating of silicone rubber surrounding the exterior of the coils of electrode minimizes tissue in-growth between the filars of the coils, while leaving a portion of the coils exposed to deliver electrical stimulation to a patient.
Another approach to preventing tissue in-growth is disclosed in U.S. Pat. No. 5,090,422, which describes the use of a biocompatible porous materials such as woven, porous polyurethane and porous polytetrafluoroethylene that may be used to cover an electrode surface. The material is insulative when dry, but becomes conductive when bodily fluids penetrate the pores of the material. The porous covering is of adequately small pore size and fibril length to preclude substantial tissue in-growth.
Yet another method of preventing tissue in-growth is disclosed in U.S. Pat. No. 5,609,622, which describes coating a lead with a porous Polytetrafluoroethylene (PTFE) layer such as may be formed of expanded PTFE (e-PTFE), and which has a pore size of less than 10 microns or smaller so that the pore size is very small, and tissue in-growth is prevented.
While the foregoing approaches are directed to preventing tissue in-growth, it may be noted that some controlled tissue attachment to a lead body or electrode may actually be beneficial in stabilizing the lead, and allowing the electrode to maintain a position at a desired implant site. For example, in leads carrying defibrillation electrodes, a change in the coil placement may increase the defibrillation thresholds. Similarly, in pace/sense applications, a shift in electrode position may alter the pacing threshold and affect capture. Promoting tissue growth for stabilizing prosthesis and other implanted structures has been disclosed in the prior art. For example, U.S. Pat. No. 5,035,713 discusses use of a re-entrant biocompatible material such as polyethylene, polyethylene teraphthalate, polypropylene, polysulfone, polylactic acid and polydioxanone to promote selective tissue in-growth to stabilize an implanted structure. Similarly, U.S. Pat. No. 5,833,664 discusses promoting tissue attachment to intrabody prosthetic devices, such as catheters, to effect improved stability of the prosthesis/tissue opening site interface.
Yet a further concern associated with the use of medical electrical leads, and in particular, the use of leads carrying coiled electrode structures, involves the possibility of a coil causing abrasion to an adjacent lead structures. For example, a coiled electrode adapted for use in the right atrium may lie in close proximity to a second lead carrying an electrode placed in the right ventricle. The coiled electrode may contact the second lead, creating abrasions in the external lead surface so that an internal conductor comes in contact with body fluids. This condition may ultimately result in lead failure. Also, in applications in which leads are positioned within relatively smaller vasculature structures, such as in coronary veins, lead-to-lead contact, or lead-to-tissue contact can be exacerbated, thus increasing the likelihood of abrasion.
Therefore, what is needed is an improved lead structure that minimizes the potential for the abrasion of adjacent structures. The lead ideally promotes selective, controlled tissue attachment to stabilize lead placement, while preventing tissue ingrowth that would prevent lead extraction.
The present invention provides an improved system and method of selectively promoting tissue in-growth on, or adjacent to, an implantable medical device (IMD). In one embodiment of the invention, a first portion of porous PTFE is provided adjacent to at least a first surface of the IMD. The porous PTFE, which may be an expandable PTFE (e-PTFE), has a pore size that is small enough to prevent substantially all tissue ingrowth. For example, the pore size may be 10 microns or less. This first portion of PTFE is adjacent at one or more selected locations to a second portion of porous PTFE. This second portion of PTFE has a pore size adapted to promote tissue in-growth. For example, the pore size of this second portion may be 20 to 50 microns. In this manner, tissue in-growth will only occur at the first surface of the IMD in the vicinity of the second portions of PTFE. At other areas of the first surface of the IMD, all tissue ingrowth will be substantially prevented.
In another embodiment of the invention, the inventive system includes a removable member that is adapted to be adjacent to at least one surface of the IMD. The removable member is formed of a first portion, or layer, of porous PTFE to substantially prevent all tissue in-growth, and one or more second portions, or layers, of porous PTFE that are provided to promote tissue in-growth in selected locations. The removable member may take the form of a sleeve, as may be adapted to slide over a portion of a lead. This sleeve may be adapted to remain in the body of a patient during a lead extraction process so that a replacement lead may be advanced within the sleeve. Because the sleeve is adapted for preventing tissue in-growth in the lead itself, the lead extraction process is greatly simplified.
According to one embodiment of the invention, each of the PTFE layers are formed of porous PTFE tubing having a thickness of 50 microns or less, and preferably less than 25 microns. The tubing may be heat-shrinkable such that it conforms to a specific surface of an electrode or other implantable medical device upon the application of heat. In yet another embodiment of the invention, the layers of porous PTFE may be formed of a tape that may be applied to the surface of the implantable medical device. In still a further embodiment of the invention, the two layers are provided by a single composite structure that has a more porous material exposed on a first surface adapted to be located adjacent tissue, and a less porous, more dense material on a second surface adapted to be situated adjacent the electrode. This type of composite structure may be formed by first creating a coating of e-PTFE having a unified density. One surface of the composite structure may then be altered to be more porous by selectably removing fibrils from this surface. Alternatively, this structure may be formed using a co-extrusion process to create the layers with different pore sizes.
According to one manner of using the current invention, a lead having at least one coil electrode is coated with an inner layer of porous PTFE such as expanded-PTFE (e-PTFE) to prevent tissue in-growth. This inner layer is surrounded by a more porous PTFE layer having a pore size selected to promote tissue in-growth. The tissue ingrowth promoted by the pore size of the outer layer is controlled such that the coil electrode is stabilized at a desired implant site by the tissue attached to this layer. Tissue is prevented from adhering to any part of the coil structure itself by the inner layer.
The current invention may be adapted for selectively promoting tissue in-growth in subcutaneous electrode arrays, and in any other type of implantable lead or electrode system. In addition to promoting tissue in-growth to stabilize the location of an implantable medical device, the current system also prevents lead abrasion cause by electrode coils rubbing against adjacent lead structures when multiple leads are in close communication with one another within a patient's vascular system.
Other aspects of the invention will become apparent to those skilled in the art from the description of the invention and the accompanying drawings.
The proximal end of the lead carries a connector assembly that includes a molded lead bifurcation sleeve 20. This bifurcation sleeve joins the lead body 10 to two different connectors at the lead proximal end. The first connector is a bipolar, in-line assembly 24, generally corresponding to the IS-1 connector standard for pacing leads. This connector 24 is provided with a first and second set of sealing rings 28 and 34, and connector pin 36. Connector pin 36 may be coupled to tip electrode 16 via an internal conductor, whereas the connector ring may be coupled in a similar manner to ring electrode 14. The second connector, which may correspond to a standard such as DF-1, is provided to couple connector pin 36 to defibrillation electrode 12.
Although the lead of
The injection of silicone around the defibrillation coils involves a process that must be closely controlled. If too much silicone is injected around the coils, the conductive capability of the defibrillation electrode may be comprised. If too little silicone is injected, tissue in-growth may not be prevented, making lead extraction difficult or impossible.
As noted above, the porous PTFE used in the construction of the inventive lead is preferably porous expanded PTFE (e-PTFE) having a microstructure of nodes interconnected by fibrils. Porous expanded PTFE may be manufactured according to the processes disclosed in U.S. Pat. Nos. 4,187,390, 3,953,566, 5,609,622, 4,096,227, 4,187,390, 4,985,296 and 5,148,806, all incorporated herein by reference. The porous PTFE may contain a carbon filler used for the surface of the conductive portion of the electrode. As is known in the art, porous PTFE may be specified by pore size, which, in turn, is generally described as a function of the fibril length of the material. The fibril length of porous expanded PTFE is measured as taught by U.S. Pat. No. 4,972,846.
Returning now to
According to one aspect of the invention, layer 310 may be treated, or infused, with of drugs to minimize thrombosis as well as to reduce the threat of infection.
In one embodiment, layers 308 and 310 are cut from tubing commercially-available from the Zeus Corporation of Orangeburg, S.C. In this embodiment, each of the layers may be very thin, having a thickness of 50 microns or less, and preferably less than 25 microns.
The tubing of both layers may be sized to fit grooved region 304. Layers 308 and 310 may be held in place using any type of biocompatible adhesive such as silicone adhesive. Alternatively, the adhesive may be a thermoplastic adhesive such as a dispersion of water and fluorinated ethylene propylene in the form of a particulate and a surfactant. A layer of non-conductive polymeric adhesive produces good adhesion with little additional electrical resistance. Alternatively, conductive fillers such as carbon black may be added to this dispersion in order to make it electrically conductive. This dispersion, both with, or without conductive fillers, may be used to adhere the electrically conductive polymeric material of the electrode surface to the underlying coil 306.
Layers 308 and 310 may be bonded together using an ultrasonic welding process, as is known in the art. In another embodiment tubing may be sized larger than grooved region 304 such that edges of layers 308 and 310 extend over regions 312A and 314A of the lead body.
According to one construction of a lead employing the current invention, sleeves 312 and 314, which may be formed of silicone or other biocompatible material, may be applied over the edges of the layers 308 and 310 and held in place by an adhesive to further secure these structures. Alternatively, a tubing structure, including heat-shrinkable tubing, may be used for this purpose. Bonding of sleeves 312 and 314 to the lead body may be enhanced by etching regions 312A and 314A of the lead body 302 using a plasma or corona etching process, or by using a chemical surface modification process such as is commercially performed by the Zeus Corporation. This creates a surface that more readily adheres to adjacent materials, allowing a superior bond to form between the lead body surface and the sleeves 312 and 314. Yet another approach to improving the bond involves utilizing an ultrasonic welding process to bond the sleeves to the surface of lead body 302.
It may be noted that the body of lead 302 may be of any conventional lead construction known in the art in the manner discussed above. For example, the exterior of lead may be formed of a silicone, a polyurethane, or a non-porous or dense PTFE. These materials do not promote tissue in-growth in the manner discussed above with respect to porous PTFE. For this reason, only limited tissue in-growth occurs along the primary portion of the lead body, with more substantial in-growth being selectively promoted only where an additional degree of stability is desired, as at the electrode.
In yet another embodiment of lead 302 or 502, the layers of porous PTFE may be formed of a tape that may be applied to the surface of the electrical conductor. For example, a porous PTFE may be formed into a thin sheet. A layer of continuous or discontinuous thermoplastic adhesive may be applied to one side of the sheet, and the material may then be cut to form tape. The tape forming the inner layer is wrapped about the conductor wire surface with the adhesive side of the composite contacting the conductor. In one embodiment, the conductor wire surface is helically wrapped with the tape, and is then heated to a temperature above the melt point of the thermoplastic adhesive to cause effective bonding of the composite tape to the conductor surface. This process may be repeated with a second tape formed using a less-dense PTFE.
The above-described embodiments contemplate the use of two individual layers of porous PTFE to selectively control tissue in-growth. An inner layer prevents substantially all in-growth, while the surrounding, outer layer selectively promotes in-growth. In one embodiment of the invention, the two layers are combined into a composite structure that has a more porous material exposed on a first surface adapted to be located adjacent tissue, and a less porous, more dense material on a second surface adapted to be situated adjacent the electrode. For example, a heat-shrinkable, tubular structure that is adapted to be positioned around defibrillation electrode 12 may have an outer surface formed of a more porous e-PTFE, with the inner surface coated with a less porous e-PTFE. Such a structure may be formed initially of a dense e-PTFE. The outer surface may then be altered to be more porous by selectably removing fibrils from the outer surface using the techniques described in U.S. Pat. No. 5,462,781 incorporated herein by reference.
Variations and modifications to the present invention may be possible given the above disclosure. For example, a composite structure comprising a first dense layer of porous PTFE surrounded by a second, less dense, layer of porous PTFE may be positioned adjacent to an outer surface of any implantable medical device, and is not limited to use with electrodes carried on leads. For example, the enclosure (can) of an implantable medical device may employ the current invention system to promote tissue in-growth over a portion of the can, if desired. Alternatively, predetermined portions of the lead body itself may employ the inventive system and method to selectively promote tissue in-growth.
According to another manner of practicing the current invention, the various layers of PTFE may be staggered such that only a portion of the first, porous layer of PTFE is coated by an outer layer of less dense PTFE. In this manner, tissue in-growth is only selectively promoted at predetermined areas of the device, while being entirely absent at other areas of the device. For example, a medical lead may be coated with a layer of more dense e-PTFE over the entire length of the lead. The lead may then-be coated with an additional outer layer formed of a less dense material over only selected portions of the lead to allow selective tissue in-growth in only certain areas, such as adjacent to an electrode to stabilize electrode positioning. This enables lead extraction to be accomplished with less tissue damage.
According to yet another aspect of the invention, a sleeve having two layers of porous PTFE according to the current invention may be provided to encase a medical device. The sleeve may be formed of an inner layer of a porous PTFE having a pore size adapted to prevent substantially all tissue in-growth. An outer layer formed of the less porous PTFE in the manner discussed above may be provided over the entire surface, or only over predetermined portions, of the inner layer to selectively promote tissue in-growth. The sleeve may be positioned over the implantable medical device prior to implant. After implant, tissue in-growth occurs at the predetermined portions of the sleeve wherein the more porous PTFE material resides. No tissue attaches to the medical device itself. Therefore, the medical device may be readily replaced. For example, a lead may be withdrawn from the sleeve and a new lead inserted into the sleeve without disrupting the in-grown tissue, greatly simplifying the lead extraction process. Moreover, the stability of the implanted medical device is enhanced by the existence of the in-grown tissue and the sleeve. It may be noted that because the sleeve is porous, current is conducted through the sleeve when the pores are filled with fluid. Therefore, a lead inserted into a sleeve and implanted within a patient may deliver electrical stimulation to the patient through the PTFE layers.
The very porous first layer 804 may be coated with a second layer 806 of porous material having a pore size that substantially prevents all tissue in-growth in the manner discussed above. Layer 806 has a thickness which may be relatively small in comparison to layer 804. For example, the pore size of this layer may be 10 microns or less, with a layer thickness that may be 10 microns or less. Providing a second layer that is relatively thin reduces overall lead dimensions.
The inventive lead of
The lead of
The sleeve of
As noted above, although
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|Lynn Mark C
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|David Muecke
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|U.S. Classification
|607/116, 607/122
|International Classification
|Cooperative Classification
|European Classification
|Sep 22, 2004
Owner name: MEDTRONIC, INC., MINNESOTA
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNORS:SOUKUP, THOMAS M.;DAHL, ROGER W.;SUNDQUIST, STEVE;AND OTHERS;REEL/FRAME:015160/0258;SIGNING DATES FROM 20040503 TO 20040916
|Dec 22, 2009
|Fee payment
Year of fee payment: 4
|Jan 20, 2014
|Fee payment
Year of fee payment: 8


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Welcome to CKO of Great Kills
If you feel like you need a supportive environment to help you lose weight and get toned, then come to CKO of Great Kills. We're a kickboxing gym that's open to all skill levels, and both men and women are addicted to our one-hour classes. We have hanging heavy bags so that gym members achieve their health goals faster through the added resistance when they punch and kick.
Our certified instructors are friendly, professional, and knowledgeable, and they'll make sure you stay on track and get the continued motivation you need to push yourself to the next fitness level. You can burn up to 1,200 calories during one of our:
- Action-filled kickboxing classes
- Personal training classes
At CKO of Great Kills, we want you to lose weight and have fun while doing it, so don't go to just any fitness center when you can enjoy the family-like atmosphere here at our kickboxing gym. Call us today to learn more about our free trial class and affordable membership rates.
4255 Amboy Road
Staten Island, NY 10308
|8:30am - 9:30pm
|8:30am - 8:30pm
|8:30am - 9:30pm
|8:30am - 8:30pm
|8:30am - 6:30pm
|8:00am - 12:00pm
|8:00am - 12:00pm