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Differences in the breast cancer burden of African American compared with White American women are well-documented. Recent controversies have emerged regarding age-appropriate mammographic screening guidelines, and these surveillance recommendations may influence future breast cancer disparities. Our goal was to evaluate age-specific breast cancer stage distributions and incidence rates of triple-negative breast cancer (TNBC) in a population-based tumor registry.
We analyzed California Cancer Registry (CCR) breast cancers diagnosed 1988 – 2006. Results were stratified by age and race/ethnicity, with White Americans identified as Non-Hispanic Whites (NHW) and African Americans as Non-Hispanic Blacks (NHB). Breast cancer stage distributions and TNBC incidence rates were also analyzed.
A total of 375,761 invasive breast cancers were evaluated (including 276,938 in NHW and 21,681 in NHB) NHB and Hispanics tended to be younger than NHW (median ages 57; 54; and 64 years, respectively). Lifetime incidence rates were higher for NHW compared to NHB and Hispanics, but for women younger than 44 years incidence was highest among NHB. NHB also had higher incidence rates of Stage III and IV disease, and higher incidence of TNBC in all age categories.
Population-based data demonstrate that African American women have a more advanced stage distribution for breast cancer compared to White Americans, and higher incidence rates for TNBC. These patterns are observed for women age 40–49 years as well as older women, and suggest that mammographic screening for early detection of breast cancer will be particularly relevant for younger African American women.
More than 200,000 women are diagnosed with breast cancer each year in the United States and approximately 40,000 are projected to die with this disease annually(1). Breast cancer mortality rates have declined over the past twenty years in the United States, and this improvement in outcome is largely explained by the combination of earlier detection with screening mammography coupled with utilization of more effective systemic therapy(2). Systemic therapy options for breast cancer are determined by the molecular marker expression of individual tumors. The best outcomes are therefore observed for cancers that are either detected early (i.e. when the distant organ micrometastatic risk is low) or that have a marker pattern indicating high likelihood of controlling micrometastases with targeted treatment such as endocrine therapy for hormone receptor-positivity and/or trastuzamab for HER2/neu overexpression. Conversely, tumors that are detected at advanced stages or that are negative for these markers are more likely to be associated with breast cancer mortality.
Population-based data regarding the breast cancer burden of different subsets of the American female population have revealed several interesting albeit incompletely-understood patterns. Most notably, African American women have a lower lifetime risk of breast cancer, but mortality rates are paradoxically higher when compared to White American women(3). The age-incidence curves also differ; among women younger than age 45 years the incidence rates are higher for African Americans compared to White Americans. Furthermore, frequency of breast tumors that are negative for the estrogen receptor (ER); the progesterone receptor (PR); and/or the HER2/neu marker is also increased among African American women(4).
Breast cancer screening with annual mammography beginning at age 40 years has been advocated since the mid-1990's by organizations such as the American Cancer Society; the American College of Surgeons; and the National Comprehensive Cancer Network. This recommendation was challenged recently by the U.S. Preventive Services Task Force (USPSTF) which issued a published statement in November 2009 in support of deferring initiation of mammography screening until age 50 years(5). Presumably, this screening strategy could have a disproportionately adverse effect on women facing an increased risk of being diagnosed with early-onset breast cancer, advanced-stage disease, and/or biologically-more aggressive tumors. The goal of this project was to assess the potential implications of the USPSTF recommendation relative to African American women, by computing age-specific, population-based stage distributions for breast cancer as well as age-specific incidence rates of TNBC. For these analyses we relied upon data from the population-based California Cancer Registry (CCR). The CCR has provided valuable information regarding disparities in breast cancer related to racial/ethnic identity since 1988 (6–9).
An analysis of the California Cancer Registry (CCR) data from 1988 to 2006 was performed. Age-adjusted and age-specific invasive breast cancer incidence rates for the three major race/ethnic groups (Non-Hispanic White [NHW]; Non-Hispanic Black [NHB]; and Hispanic) were computed using data from the CCR. The CCR is a population-based cancer registry which has monitored cancer incidence and mortality in California since 1988. SEER*Stat 6.5.2 program was used to analyze the CCR database, including 95% confidence intervals(10). Statistical significance testing was based upon chi-squared comparisons for categorical variables and based upon student's t-test to compare the mean values of continuous variables. P-values of less than 0.05 were considered statistically significant.
The CCR database for breast cancer was analyzed by American Joint Committee on Cancer (AJCC) seventh edition stage at diagnosis, stratified by age (categorized as <40 years, 40 to 49 years, 50 to 59 years, 60 to 74 years, and >=75 years) and then comparisons were evaluated with respect to the racial/ethnic subsets of the California population. Racial/ethnic identity was assigned by self-report as documented by the tumor registries contributing to the CCR program.
Staging information and positive versus negative hormone receptor status (estrogen receptor, progesterone receptor) was also assigned according to the information contributed by the CCR registrars. For HER2/neu expression, positive or negative status was based upon documented immunohistochemistry and/or FISH staining. Statistics for TNBC incidence rates were limited to cases diagnosed beginning 2004. Documentation of HER2/neu status was felt to be more uniform and complete during this latter interval, when clinical trial results regarding effectiveness of adjuvant trastuzamab for HER2/neu-overexpressing breast cancer were more widely-available and this component of molecular marker information therefore became more relevant on a routine basis for all women diagnosed with invasive breast cancer (11, 12).
A total of 375,761 women were newly-diagnosed with invasive breast cancer as reported in the California Cancer Registry from 1988 – 2006. Of these, NHW accounted for 278,241 (74%); NHB accounted for 21,716 (5.8%); and Hispanics 45,523 (12.1%).
The median age at diagnosis was 64, 57, and 54 years for the NHW, NHB, and Hispanic patients, respectively. The median age at diagnosis for patients with unknown racial/ethnic background was 61.5 years. As demonstrated by the age-incidence rates shown in Table 1 and the age-incidence curves depicted in Figure 1, the risk of breast cancer rises with increasing age for all of the racial/ethnic subsets evaluated. Figure 1 also shows that among women younger than age 44 years, population-based incidence rates of breast cancer are highest for NHB; for women older than 44 years, incidence rates are highest for NHW. Incidence rates are lowest for Hispanic women in all age categories. Incidence rates of Stages 1 and 2 breast cancer were lower for NHB compared with NHW in all age categories, but incidence rates for Stages 3 and 4 disease were higher for NHB. Breast cancer incidence rates by any stage were generally lower for Hispanics compared with NHW in all age categories.
Figure 2 shows the incidence rates by stage for the study population subsets, and demonstrates the shift toward more frequent detection of advanced-stage disease (stages III and IV) for NHB compared to NHW and Hispanics.
As shown in Figure 3, most of the rising breast cancer incidence rates associated with increasing age is a consequence of increasing risk for non-triple negative breast cancer (TNBC). Incidence rates for TNBC are less than 50 cases per 100,000 population (all race-ethnic groups combined) in all age categories, but these rates slowly rise with age and plateau beyond the fifth decade of life.
Table 2 and Figure 4 demonstrate the increased risk of TNBC for NHB women in all age categories. Incidence of TNBC rise more steeply with increasing age for NHB compared to NHW and Hispanics, with these incidence rates approximately twofold higher for NHB compared to either of the other subsets in the 40–49 and 50–59 year-old age categories. The TNBC incidence rates peak at 64.4 per 100,000 NHB in the 60–74 year-old age category.
Recent challenges to the traditional recommendations that American women initiate annual screening mammography at age 40 years have the potential for exerting a disproportionately adverse effect on African American women because of the well-documented younger age distribution for breast cancer in this population subset. Early detection of breast cancer is the most powerful determinant of outcome, and this will be particularly relevant for tumors expressing phenotypes that cannot be controlled with targeted agents such as endocrine therapy and/or trastuzamab. African American women have higher mortality rates from breast cancer, and this is at least partially explained by the fact that they tend to present with more advanced stages compared to White American women. They therefore represent a community that has been the focus of many breast cancer awareness and screening/early detection programs. Our study provides further evidence of the need to continue intensive breast cancer surveillance among African American women age 40–49 years. By studying data from the California Cancer Registry, we found higher population-based incidence rates of locally-advanced breast cancer and triple-negative breast cancer among African American women.
Although the lifetime incidence rates of breast cancer are higher for White American compared to African American women, the Surveillance, Epidemiology and End Results (SEER) Program documents that for women younger than age 45 years, population-based incidence rates are higher for African Americans(13). Several investigators have demonstrated that the frequency of TNBC is higher for African American compared to White American breast cancer patients (14–17). Carey et al (18) furthermore demonstrated that the risk of triple-negative breast cancer is particularly high among premenopausal African American women, based upon analysis of the Carolina Breast Cancer Study. By reporting on age- and race/ethnicity- specific patterns of disease in the California Cancer Registry, our study provides powerful population-based evidence regarding the importance of aggressive screening for early detection of breast cancer in young African American women.
As background for the updated screening guidelines presented by the U.S. Preventive Services Task Force (USPSTF) in November 2009(5) reviews of the data from the historic mammography screening trials were prepared by Nelson et al(19) and Mandelblatt et al on behalf of the Cancer Intervention and Surveillance Modeling Network (CISNET)(20). In summary, they found that for women age 40–49 years, approximately 1900 must be invited to mammographic screening in order to save one life; for women age 50–59 years, approximately 1300 must be invited; and for women age 60–69 years, approximately 400 must be invited. They also found that initiation of mammography screening at age 40 rather than age 50 years results in an average gain of 33 life years per 1000 women screened. CISNET therefore stated: "If the goal of a national screening program is to reduce mortality in the most efficient manner, then programs that screen biennially from age 50 years…are among the most efficient on the basis of the ratio of benefits to the number of screening mammograms. If the goal of a screening program is to efficiently maximize the number of life-years gained, then the preferred strategy would be to screen biennially starting at age 40 years."(20) The USPSTF opted to advocate in favor of supporting an efficiency-based screening model rather than a longevity-based program, and they therefore issued the statement that "The USPSTF recommends against routine screening mammography in women aged 40–49 years… The USPSTF recommends biennial screening mammography for women between the ages of 50 and 74 years."(5) CISNET furthermore commented that none of the mammography screening models were likely to capture differences in outcome among specific population subsets such as "black women who seem to have more disease at younger ages than white women"(20). The USPSTF recommendation statement did not comment on the potential impact of their screening recommendations on race-ethnicity-associated breast cancer disparities.
Our study serves to inform the discussion regarding relevance of mammography screening for African American women age 40–49 years. We found more advanced stage of disease at diagnosis in these younger African American women, and we also found higher incidence rates of TNBC for this population subset. Since mammography screening programs should improve early detection rates for breast cancer, and since early detection of TNBC is critical for improving its successful treatment, we believe that our study findings provide compelling evidence that screening mammography should be particularly important for young African American women. The USPSTF recommendation that routine screening mammography should not be initiated until age 50 years has the potential for widening the magnitude of breast cancer outcome disparities between African American and White American women.
The CCR data on race/ethnicity-associated frequency of TNBC is consistent with other studies, as shown in Table 3. The population-based incidence rates featured in our study serve to strengthen the validity of these observations. These rates indicate an inherently higher risk of TNBC for NHB/African American women, refuting the argument that the larger proportion of TNBC in African American women is an artifact of the "denominator" phenomenon (i.e. African American women appear to have more TNBC simply because they have fewer total breast cancers compared to White American women). Our data on women from California demonstrate increased population-based risk of TNBC for NHB women.
Our study is limited by our unfortunate inability to correlate mammography screening information with the age- and race/ethnicity-specific breast cancer incidence rates. However data from the California Health Interview Survey (CHIS) indicate similar mammography utilization rates for African American and White American women, but somewhat lower rates for Hispanic/Latina women (unpublished data) and this finding mirrors national data on mammography utilization reported by the American Cancer Society(1). Although the data regarding effectiveness of mammography in detecting TNBC (compared to detection rates for non-TNBC) are limited, the available published studies indicate that frequency of mammographically-occult breast tumors is similar for TNBC and non-TNBC. TNBC does however, appear to be less-frequently associated with microcalcifications and is more likely to be identified as a mass or asymmetric density(21–24). Furthermore, Ma et al demonstrated that mammographic density (a common imaging finding among premenopausal women) is a risk factor for TNBC as well as for non-TNBC(25).
Another notable limitation of our study is the fact that the CCR (similar to the SEER Program) lacks detailed information on menstrual history and reproductive factors. Millikan et al(26) and other investigators(27) have suggested that childbearing patterns and lactation history may account for race/ethnicity-associated variation in breast cancer burden. Others have been unable to confirm these hypotheses (28). Yet other investigators have reported elevated risk of TNBC among contemporary female populations of continental Africa(29–31), suggesting that African ancestry may be associated with some heritable risk factor for TNBC(32). Our population-based California dataset is unable to address any of these issues.
In summary, our data from California (which appears to be representative of national data) demonstrates increased risk of advanced-stage breast cancer and triple-negative breast cancer in African American women compared to White American and Hispanic American women. These patterns are notably prominent for women younger than age fifty, suggesting that mammography screening to improve early detection of biologically-aggressive patterns of breast cancer will be particularly relevant for younger African American women, especially since overall breast cancer incidence rates are higher for African American women in the premenopausal age range.
The collection of cancer incidence data used in this study was supported by the California Department of Public Health as part of the statewide cancer reporting program mandated by California Health and Safety Code Section 103885; the National Cancer Institute's Surveillance, Epidemiology and End Results Program under contract N01-PC-35136 awarded to the Northern California Cancer Center, contract N01-PC-35139 awarded to the University of Southern California, and contract N01-PC-54404 awarded to the Public Health Institute; and the Centers for Disease Control and Prevention's National Program of Cancer Registries, under agreement 1U58DP00807-01 awarded to the Public Health Institute. The ideas and opinions expressed herein are those of the author(s) and endorsement by the State of California, Department of Public Health the National Cancer Institute, and the Centers for Disease Control and Prevention or their Contractors and Subcontractors is not intended nor should they be inferred.
A special thanks is warranted to our coders, without whom the registry would not be possible. In particular we are grateful to Ellen Malek, CTR, for her wisdom and insight regarding the data, and its translation into the CCR.
Authors do not have any financial disclosures.
Kathryn C. Amirikia, University of California San Francisco, Fresno.
Paul Mills, University of California San Francisco, Fresno.
Jason Bush, California State University, Fresno.
Lisa A Newman, University of Michigan.
PubMed Central Canada is a service of the Canadian Institutes of Health Research (CIHR) working in partnership with the National Research Council's national science library in cooperation with the National Center for Biotechnology Information at the U.S. National Library of Medicine(NCBI/NLM). It includes content provided to the PubMed Central International archive by participating publishers.


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Play golf in Torquay, the heart of the English Riviera
- The Club introduces Preferred Lies w.e.f 17th October
- New Facebook Page up and running - Torquay Golf Club 2016
- Tables available for Christmas Ball at Palace Hotel
We are a thriving and traditional members club situated just three miles from Torquay's centre with its stunning marina and harbour, and a short distance from picturesque St Marychurch and Babbacombe.
Founded in 1909, the course has steadily evolved to present a first class parkland layout that offers a challenging yet rewarding test of golf in beautiful natural surroundings. Extensive views from the course encompass Lyme Bay in the east across the water to as far afield as Portland Bill, and to the rugged tors of Dartmoor to the west. Our tree lined fairways and high quality greens present an interesting challenge on each hole.
We offer a warm welcome to visitors and societies looking to test your skills; Torquay golf course provides a true test of golf for players of all abilities. Visitor green fees are available throughout the week and weekend.
To match the course, our comfortable and friendly clubhouse offers excellent catering and bar facilities where you can have a relaxing meal and a drink on the terrace overlooking the 1st and 18th fairways. We hope you enjoy your visit!see the course Online Tee Booking
Tuesday 25th 6:03 am
Ladies day 9-12.30Monday 24th 8:31 am
Dark wet start to the day, should you wish to play there's no reservationsSaturday 22nd 6:17 am
Turkey trot 8am-1.30pm
Upcoming Events
Tue 25 Oct
Ladies Day - EG Medal/MMP8/Millenium Cup/Breakthrough Brooch
09.00 to 12.28
Thu 27 Oct
Evening Bridge
19.00 - 22.00
Fri 28 Oct
Club Night - informal dining and Entertainment
Sat 29 Oct
Turkey Trot 2
08.12 to 12.36
Sat 29 Oct
Private Function
Sun 30 Oct
Alternate Day Ladies
09.32 to 09.40
Sun 30 Oct
BST Ends - Clocks Go Back
Tue 01 Nov
Ladies Day - County Stableford
09.00 to 12.28
Thu 03 Nov
Evening Bridge
19.00 - 22.00
Thu 03 Nov
Ladies Seniors
Senior Ladies
09.32 to 10.04
Local Weather

subset: commoncrawl


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Woman dies in crash involving bus, police cruiserhttp://www.vttoday.com/woman-dies-in-crash-involving-bus-police-cruiser/ | April 18,2013MORE IN This Just InPUTNEY A local women told police someone stole $400 in cash from her car. Full StoryThe Raiders had two goals in a span of about five minutes on Tuesday in upending Middlebury 2-1... Full StoryNORTH CLARENDON Often when a No. 3 seed plays a No. Full Story
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Drug task force arrests 28
Courthouse employee honored for service
PARSONS – Longtime courthouse employee Dave Kyle received recognition and thanks from the Tucker County Commission and county employees Friday.
Kyle will officially retire as director of maintenance for the Tucker County Courthouse Dec. 31, after 25 years of service.
"We have an employee that is retiring," Tucker County Commissioner Mike Rosenau said during the ceremony at the courthouse. "Dave Kyle is retiring – you have all worked with him. Dave's jokes have kept us moving at times. On behalf of the Commission, I want to thank Dave for 25 years of dedicated service."
Commissioner Lowell Moore said Kyle was a complete professional.
"He has been so helpful, and we will all miss him around the courthouse," Moore said. "He has done a great job and we are fortunate to have had him all this time. We wish him the best in his retirement."
"I have worked with Dave Kyle for 20 years," Tucker County Clerk Sherry Simmons said. "We are friends and co-workers. Whenever we needed anything, Dave took care of it. He was more than just a maintenance man – he was our friend. He is going to be very missed and the new fellow coming in will have big shoes to fill.
"I cannot say enough about Dave Kyle," Simmons said. "I thank him for his years of service."
Kyle said he has enjoyed his years working at the courthouse.
"My favorite thing has been taking care of the old courthouse, especially the clock tower," Kyle said. "The tower is the oldest thing here and twice a week I would climb up to the tower and wind the clock. The mechanisms on the crank have about 300 pounds of weight. It is not easy, but I enjoy it."
Kyle said he will miss the people he works with.
"It will be rough not to see everyone everyday," Kyle said. "But I told them I would come back and visit."
Once he retires, Kyle said he will make time to do the things he wants to do.
"I will enjoy spending time in the country," Kyle said. "I like it out there. I will hunt and fish – I haven't had time to fish for years."
Kyle said he will also spend time with his grandson, who is 10 years old. He said he also has a 17-year-old granddaughter who lives in Pennsylvania, and he hopes to see her more as well.


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Privacy Advocates Worry That In Your Car, Big Brother Is Riding Shotgun
Aug 13, 2014
It has long been a nightmare scenario for privacy advocates: Every time you get in your car, a computer relays your location and tracks your trip from start to finish. It can track how far you go, where you drive, how long the trip is, and even how much traffic you encounter.
Read the full story at nationaljournal.com.


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- Nimetön
- Englanti, Mies, 18-24
- Aloitteleva kulkuri
- 1 Arvostelu
Incredibly noisy. Plays loud music every night until 12pm which you can hear very clearly from the rooms. In the morning cleaners arrive at around 8am and are also very loud and shout in the courtyard. Very basic facilities, hostel don't even provide soap
- Nimetön
- Yhdysvallat, Mies, 41+
- Ahkera matkaaja
- 10 Arviot
My first time to Capetown. This is a wonderful place to stay a week. Nice and friendly and helpfull. Its 2016 LOL wifi should have been free use or need to have the WiFi included in payment to use all over the place.
- Nimetön
- Intia, Mies, 18-24
- Aloitteleva kulkuri
- 3 Arviot
Great place to stay. Friendly people all around. Prime location and very close to the clubs and bars. Cleanliness was the only issue with toilets and rooms not cleaned even once during my entire stay (4 days).
- Nimetön
- Intia, Mies, 31-40
- Aloitteleva kulkuri
- 2 Arviot
Long Heart with long street. Given me the best of beds and also helped me as I met with accident. Greatly appreciated and would love to visit again.
- jwork1813298
- Yhdysvallat, Mies, 25-30
- Maailmanmatkaaja
- 41 Arviot
well well what can i say. I had 3 travelers recommend this place, there stay stretching back as much as 5-7 years ago. This place is about 20yrs old, it has some serious history in there and you can see that when you visit the font desk/bar. The staff is pretty hipster and they are as helpful as they can be. you really get every kind of traveler in here. old people, young people, crazy people, dusty backpackers, quiet German kids, and the mix of aussie/brits looking to get crunk at the bar.
- Nimetön
- Sveitsi, Mies, 25-30
- Aloitteleva kulkuri
- 1 Arvostelu
Bei der Ankunft im Zimmer war das ganze Bett voller Hundehaare, die Badewanne(Dusche) war mit 10cm Dreckwasser überdeckt über 2 tage. Und wer vor 2Uhr Morgens schlafen gehen will, hat mit lauter musik von der reception zu kämpfen. Wir haben 3 nächte gebucht im voraus, sind dann abr nach der ersten Nacht weitergezogen.
Tee varaus matkan varrella uusien Hostelworld-matkapuhelinsovellusten avulla.


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Trovagene, Inc. (TROV) Receives Milestone Payment From Ipsogen S.A. 0 commentsAug 29, 2012 5:42 PM | about stocks: TROV
Trovagene is developing its patented technology for the detection of transrenal DNA and RNA, short nucleic acid fragments, originating from normal and diseased cell deaths that cross the kidney barrier and can be detected in urine. The company is leveraging its intellectual property through out-licensing agreements.
The company today announced that it has received a milestone payment from Ipsogen S.A., a subsidiary of Qiagen N.V. (Nasdaq: QGEN). This payment comes from a co-exclusive license agreement to manufacture and sell diagnostic kits for the detection of nucleophosmin protein (NPM1) mutations in patients with acute myeloid leukemia (AML). The payment was triggered by issuance of U.S. Patent 8,222,370 that is part of a family of patents filed by Trovagene around nucleophosmin protein that cover NPM1 mutations in AML.
AML is a clinically heterogeneous disease with about 200,000 new cases per year worldwide. Subgrouping of AML patients using chromosomal abnormalities provides for more individualized patient prognosis. But in nearly half the cases, the chromosomes appear normal and provide no guidance to doctors. However, a discovery by Drs. Brunangelo Falini and Cristina Mecucci at the Institute of Hematology at the University of Perugia in Italy showed that many AML patients have mutations in the NPM1 gene and that these mutations are a marker for more favorable clinical outcomes.
The National Comprehensive Cancer Network, which sets clinical standards for cancer treatment, has now included testing for NPM mutations in their clinical practice guidelines. To date, it has granted nonexclusive sublicenses to offer mutation analysis of NPM1 as a laboratory service to Laboratory Corporation of America Holdings, InVivoScribe Technologies, Warnex Medical Laboratories, Fairview Health Services of Minneapolis, Minnesota, and Munchner Leukamielabor GmbH in Munich, Germany. The company also has granted co-exclusive licenses to manufacture and sell NPM1 mutation assays to Ipsogen and Asuragen, Inc.
For additional information about Trovagene and its intellectual property, please visit the company's website at trovagene.com
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The Winnebago Destination 37RD is premium fifth wheel built with charm and attention to detail! This impressive RV will go where you want to go and in style! The high-gloss gel coat fiberglass walls, painted fiberglass front cap, and black exterior trim and molding are sure to turn heads on the road. The drop frame chassis, Trail Air rubberized suspension, and Correct Tract alignment system are sure to make your trip a breeze! Outdoors, you'll be able to enjoy the electric power awning with LED lighting and the generous storage compartments.
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Product details
A contemporary glazed oak rebated door pair with clear glass. The clear glass will allow light to flow between two rooms and create a stunning open living setting. Matching panelled and glazed doors available for a complementary look in your home. Paint n peel system for an easy finish.
- Features: Rebated door pairs include master and slave doors to give a smooth flush finish. Engineered construction for greater strength and stability. A-Grade American white oak veneer for better colour consistency.
- Part of the Blenheim collection
- Fixings: Sold separately
- Dimensions: (H)1981, (W)1524, (D)40cm
- Weight: 69kg
- Colour: Neutral
- Material: Oak
- Effects and finish: Glazed finish
- Guarantee: 10 years
- Care instructions: For handling, storage, installation and ancillary finishing and maintenance information consult the instructions on the back of the label included in your door packaging
- Industry standards or certification: FSC® Certified
- Door may be trimmed up to: (H)12, (W)12mm
Blenheim 3 Panel Glazed Rebated Oak Internal Double Doors - 1524mm Wide 459214
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Blenheim 3 Panel Glazed Rebated Oak Internal Double Doors - 1524mm Wide
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{"calculators": { "calculator": { "pimProductAttr": ["", "", "", ""], "calcType": "" } } }


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Laoisioch Mac an Bhaird
From Wikipedia, the free encyclopedia
Laoisioch Mac an Bhaird, Gaelic-Irish poet, fl. c. 16th-century.
A member of the Mac an Bhaird family of professional poets, Laoisioch is known from two surviving poems, A fhir ghlacas a ghalldacht, Dairt sonn dá seoladh go Tadhg and Mo chean duitsi, a thulach thall.
- The Surnames of Ireland, Edward MacLysaght, 1978.
External links[edit]
- http://www.ucc.ie/celt/online/G402143/header.html
- http://www.irishtimes.com/ancestor/surname/index.cfm?fuseaction=Go.&UserID=
|This article about an Irish poet is a stub. You can help Wikipedia by expanding it.


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The weekend of racing starts on Saturday 22nd and Sunday 23rd April 2017.
We hope you have a
fantastic experience at
the 20th Anniversary Run Balmoral
The Devil of Deeside Challenge at Balmoral
Entries open for the 20th anniversary 2017 races to be held on 22nd and 23rd April. more
Win £250 for your school
Fantastic opportunity for pupils to design RunBalmoral 2017 race t-shirts – and to win £250 for your school. more
2016 Annual Report
2016 Run Balmoral Annual Report now available to download more
Featured news by the Run Balmoral Events Team
We are delighted to announce that RunBalmoral 2017 will be held over the weekend of Saturday 22nd and Sunday 23rd April.
Entries will open on the 25th October for the programme of eight races catering for all age groups.
This will be the 20th year of the event and we will once again look forward to welcoming more than 5,000 entrants and as many spectators to the estate.
Put it in your diary now!
James Knowles
Chairman, Balmoral Road Races Ltd, May 2016


text:
If you've listened to the radio, glanced at a pop-up ad or checked your spam folder, you've no doubt been subjected to highly questionable ads that guarantee you "free" iPods or iPads if you do a whole lot of fine print stuff, and more. Apple is fed up with being associated with such offers, and is attempting to shut them down.
Apple Cracks Down On Sketchy "Free iPad, iPhone" Third-Party Giveaways
By June 2, 2011


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|← Previous - you wanna step?
|yow-yowing - Next →
Definition of yow
- a general exclamation.
Yow, that's a nice rig!
Yow, that hurt.
- See more words with the same meaning: computer slang.
Last edited on Nov 15 2011. Submitted by WalterGR (via TheJargonFile) on Aug 14 2009.
|Add a definition for this slang term
More info:
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Related words
Slang terms with the same meaning
Other terms relating to 'computer slang':
|Definitions include: acronym for "For The Loss."
|Definitions include: to overwhelm a web site with massive amounts of traffic due to Slashdot linking to it.
|Definitions include: as bad as possible.
|Definitions include: marketing material.
|Definitions include: acronym for "way TMI", i.e. "way too much information".
|Definitions include: a chronologically-ordered collection of articles, posted to the world-wide web, about any topic.
|Definitions include: acronym for "be back later".
|Definitions include: acronym for "I am not your lawyer".
|Definitions include: acronym for "sorry, could not resist".
|Definitions include: the totality of all blogs.
|Definitions include: acronym for "I fucking love you" or "I freaking love you".
|Definitions include: to test something before it is released or presented.
|Definitions include: impressive or flashy.
|Definitions include: "I love you too".
|Definitions include: prefix added to a noun to make it Internet-related.
Slang terms with the same root words
Other terms relating to 'yow':
|Definitions include: Arguing, fussing and fighting loudly.
How common is this slang?
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Some wikis use a different format for links, so be sure to check the documentation.
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Galapagos Islands
Isabela II
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"The ship was very comfortable, the food excellent and the itinery well planned giving us a wide range of experiences and activities without leaving us exhausted. The naturalists were amazingly knowledgeable and dedicated."
PT, Peterborough | February 2014
Isabela II is one of the longest-serving first class ships in the Galápagos and was always the leader in her class, but nowadays maybe other newer models have superseded her exalted position. I felt as though some of the newer amenities such as the Jacuzzi looked as though they had been bolted on, rather than integrated into the design. That said, the cabins were impeccably clean and very comfortable.
Ben Line
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Derniers Documents
- Des productions agricoles et pastorales bonnes à très bonnes attendues pour la campagne 2016/201726/09/2016
- Sécurité Alimentaire et Implications Humanitaires en Afrique de l'Ouest et au Sahel - Note conjointe FAO/PAM, Août 201626/09/2016
- Madagascar - Bulletin de situation acridienne N. 29 - juillet 201621/09/2016
- Madagascar - Bulletin de situation acridienne N. 28 - juin 201620/09/2016
- Madagascar - Bulletin de situation acridienne N. 27 - mai 201623/08/2016
Cluster Coordination Guidance: Guidance for FAO staff working at country level in humanitarian and early recovery operations
About this guidance material Audience: This guidance material is intended for FAO staff, in particular FAO Representatives and Emergency Coordinators at country level. It may also be useful for FAO staff at regional and headquarters levels and other agriculture and food-security stakeholders.
Purpose: To provide FAO staff with (i) essential information on the purpose and functioning of clusters, and the role and responsibilities of FAO within a cluster system, and (ii) practical guidance on what FAO staff need to do to fulfil those responsibilities. The focus is on clusters at the country level where FAO may lead, co-lead, or be a member of clusters dealing with food security, agriculture, livelihoods or nutrition.
Structure: Part I (chapters 1 and 2) provides essential information in the form of answers to frequently asked questions. Part II (chapters 3 to 6) provides practical guidance in the form of short aide-mémoire. The annexes provide key reference materials. All chapters provide cross-references to other documents where more detailed information and guidance can be found. The CD-ROM will include the documents referred to, with hyperlinks from the text.


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Chico Enterprise-Record
Simone (2002)
"Director Andrew Niccol...demonstrates a wry understanding of the quirks of fame. His healthy sense of satire is light and fun...."
"Goldies Hawn is irrestible in this funny movie. But the treatment of Arabs is groanable and cliched."
"This one gave me nightmares when I first saw it in 1972. Okay, so I'm a whimp but the creepy camp is cool."
"What's not to like about this classic film which features two of our most beloved actors at their best?"
"The talented and clever Robert Rodriguez perhaps put a little too much heart into his first film and didn't reserve enough for his second."
K-19: The Widowmaker (2002)
"As commander-in-chief of this film, Bigelow demonstrates a breadth of vision and an attention to detail that propels her into the upper echelons of the directing world."
Reign of Fire (2002)
"I have two words to say about Reign of Fire. Great dragons!"
Men in Black II (2002)
""Men in Black II," has all the earmarks of a sequel. The story is less vibrant, the jokes are a little lukewarm, but will anyone really care?"
The Deep End (2001)
"Unbidden, Alek (Goran Visnjic) gives Margaret what she wants from her family: recognition. Maybe that's all that any woman wants from her family."
Minority Report (2002)
"The two main women in this film make the Pre-Crime Unit possible, but don't benefit themselves. Guess the future isn't that much different. The guys are still having all the fun, while the girls either make that possible or sit by and watch."
Spider-Man (2002)


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About this recipe:
A family favourite! Great served with a crisp green salad and garlic bread.
Looks delish! just wondering what do you mean by soft cheese? what cheese did you use?
- 19 Jan 2012
Used different ingredients.
I used a tin of chopped tomatoes instead of passata, and skipped the rosmary.
- 20 Aug 2009
The whole family loved this recipe, it was lovely and I will be adding this to my favourites. thanks for a great recipe.
- 23 Jan 2010
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8 Holiday Dessert Recipes inspired by the Superfood Coconut
It's here! It's finally here….
{Share this e-book on FACEBOOK with friends and family you want to bake
for with you:)}
If you follow me on Facebook, you saw last Tuesday that my tests results came back:
Turns out that not all doctors are created equally. After 10+ years, I *finally* have answers to all lingering gut issues…..a little scared, but mostly beyond grateful!!!!
Back in October, I mentioned procrastinating on getting all these tests done. But then I got worse and super motivated when I found out that my doctor, Dr. Sunjya Schweig, is Chris Kresser's doctor, too!
I was not prepared to find out so much. And yet, I can't help but feel grateful. I am still deciding what pieces of the information to share publicly. And today was not the day to do so, partially because I'm still processing it and figuring out how to do this "newer life" I so desperately need to do.
But mostly, today was not the day to do it because I'm focused on the positive which is the fact that this e-book, and these brand new recipes, are here!
There are 8 in total, and 4 of which are mine.
8 Holiday Dessert Recipes inspired by the Superfood Coconut
Honey Vanilla Bourbon Peanut Butter Fudge
Yes, with the A Loving Spoon Honey Vanilla Bourbon Peanut Butter! (You'll need 3 jars. Better grab yours now. And p.s. we just started putting the Holiday Gifts up today. We are already down to just 3 left on this one!)
When I visited Nutiva last week, Chef Shanna tried them and said,
Oh my God. What is in those? Those are amazing! Is that alcohol in there? Wow.
I replied,
No, no there is no alcohol in them. That's the secret to the Honey Vanilla Bourbon Peanut Butter…..the vanilla. It's unlike any you've ever had before. You can't buy it in the store. It's exclusive to the flavor.
I made these for our Holiday Party last year. They were such a hit that I debated ever giving the recipe out. Alas, I have…..you're welcome.
Old-Fashioned Donuts with a Cranberry-Chia Glaze
Did I ever tell you that we call Samarah, "Josephine" sometimes? Her full name is: Samarah Josephina Hoffman, and Josephina comes from my grandmother, Josephine.
I always get emotional around the holidays. I'm not even sure why, but I think it's because it's the one time of year when I remember so much. Wait, or maybe it's because I found out at far too young of an age that Santa isn't real?!
Either way, I have so many great memories. My grandmother Josephine's donuts are one. Her house always smelled like a freshly baked one. I manipulated her recipe to make them gluten free 2 years ago. This time, I also made them grain free (and they are so much better).
p.s. I have created yet another donut recipe you might enjoy for the holiday season, Pumpkin Spiced Donuts.
Baked Apple Stuffed Crumble
I realize there a million baked apple stuffed something-or-others out there already.
You've probably had several.
But honestly, you've never had a stuffed crumble until you've had one that includes a crumble filled with chia seed and hempseed.
I didn't put ice cream on mine, but you should. I mean, you really should right as this warm lovely comes strolling out of the oven.
No-Bake Candied Sweet Nuts
Fair warning: If you place these in the freezer as a save-for-later snack, be aware that when you take them out of the freezer to consume, there may not be any left to share with anyone else.
I'm serious.
Crunchy. Sweet. No Bake. Chocolate, but no dairy.
No-Bake Herbed Nuts
Not everyone craves sweets like me, so I wanted to make a no-bake version that was more savory.
I used Red Palm Oil (but please if you make these, be sure you're using Nutiva's Red Palm Oil which does not contribute to deforestation), and added some herbs with just a hint of sweet.
Full Table of Contents
Seriously, the e-book is free.
I am grateful for Nutiva.
I am grateful for you.


text:
Skip to comments.Dr. Alveda King to Address the Restoring Honor Rally at the Lincoln Memorial August 28
Posted on 08/26/2010 11:28:07 AM PDT by topher
Dr. Alveda King to Address the Restoring Honor Rally at the Lincoln Memorial August 28
Priests for Life
Date: August 20, 2010
Atlanta, GA Dr. Alveda King, Director of African American Outreach for Priests for Life, issued the following statement today on her upcoming appearance at the August 28th Restoring Honor Rally on the steps of the Lincoln Memorial organized by commentator Glenn Beck.
Dr. Martin Luther King, Jr.s legacy, like the Lincoln Memorial itself, belongs to all Americans. I am participating in Glenn Becks Restoring Honor Rally not to advance any political agenda, but to advance the concept of honor in our nation.
The Book of Proverbs teaches that before honor comes humility. The Restoring Honor Rally has been organized for the purpose of giving honor to those who have humbled themselves to serve each and every one of us by defending our freedoms. If our soldiers dont deserve honor, I dont know who does.
My Uncle Martins dream was not that we should be judged by our support for bigger or smaller government, but rather by the content of our character. His dream was that everyone be guaranteed the unalienable rights to life, liberty, and the pursuit of happiness. His dream goes beyond politics, its about the condition of our hearts. That is what I intend to address on August 28.
Priests for Life is the nation's largest Catholic pro-life organization dedicated to ending abortion and euthanasia. For more information, visit Priests for Life website.
The response to this is that Dr. Alveda King, niece of MLK Jr., will be attending this event, and will address the crowd.
That should make those MSNBC minds explode.
"That should make those MSNBC minds explode."
Not much of an explosion, more like a small sizzle maybe.
The drugs got there first. They have no minds left.
to find articles...
Like a happy snap throw in the ocean..... pfft....
The head of the NAACP is having a cow over this rally.
I am so looking forward to this event. I will be there with bells on!!!
I know all about the NAACP after watching audience members in ths Sherrod video.
dude family website.
Alveda King speaks on whether her uncle Martin Luther King Jr. would stand with Glenn Beck or
The full title of this article on the original site The Daily Caller is:Alveda King speaks on whether her uncle Martin Luther King Jr. would stand with Glenn Beck or NAACP on Aug. 28
Read more at: http://dailycaller.com/2010/08/23/alveda-king-speaks-on-whether-her-uncle-martin-luther-king-jr-would-stand-with-glenn-beck-or-naacp-on-aug-28/#ixzz0xjusHq7r
Guess he/she hasn't seen the same pic posted the other 10,000 times here at FR... :-)
Sorry if this has already been addressed, but will this event be on TV?
Beck said C-SPAN wanted o cover it (and they should); but there was an issue about permits to lay the necessary cables or some such...they were trying to get the specifics worked out...
o = to...didn't catch it in time.
It is unclear if C-Span will carry it or some other group.
I will check with someone who might know
That's what I was thinking but he/she has been a Freeper since 2002.
I saw that, as well...what are the odds of missing that photo after all these years?
Hey... SHE can't speak at that awful gathering.. why, that would make her a... a... RACIST or something!
The moonbats, Al Sharpton, and the NAACP are in for a rough time.
Black Leaders to Join Glenn Beck in DC
A group of African American Leaders will stand with Glenn Beck and David Barton in Washington, DC for the 8/28 Rally. Yours truly, Alveda King will be there.
Reverend Dr. Carlton W. Veazey, President and CEO, Religious Coalition for Reproductive Choice and minister, National Baptist Convention USA;
Reverend Walter Fauntroy, civil rights activist and Pastor Emeritus of New Bethel Baptist Church in Washington, DC;
Reverend Christine Wiley, co-pastor of Covenant Baptist Church in Washington, DC.;
Dr. Willie Parker, womens reproductive health provider and board member, Physicians for Reproductive Choice and Health;
Jill Morrison, senior counsel, National Womens Law Center;
Loretta Ross, national coordinator, SisterSong Women of Color Reproductive Health Collaborative;
Reverend Timothy McDonald, pastor of First Iconium Baptist Church in Atlanta, GA, and Chair, African American Ministers in Action.
Wow! You're right! I didn't notice that when I posted. Sheeze... that's an odd group.
boody exploding head is not good in case kids are viewing this site.
I just checked, and yes, c-span.org will be streaming it live. That probably deserves to be a thread in and of itself.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.


text:
After the popularity of its Virtual Reality outdoors's inaugural exhibition, the Phi Centre is proud to announce the Garden's upcoming programming: a series of works produced by the newest York occasions.
Adding all this toward already-tremendous sense of wiping away hordes of baddies with a well-timed capability modification, RoS could be the defining activity RPG for all of us. It is a game we are going to be playing for a long, long time at EarthCheats.com.
Digital reality could after that come to be comparable to the Singularity, a concept explained by Ray Kurzweil, a futurist and Bing professional, amongst others: an easy method for our minds to split up from our anatomies and, uploaded into an electronic world, live on whilst our physical selves grow old and die.
The new licensee, Wizards of the Coast , started creation of a new roleplaying online game using their d20 program As for western End Games, in 2004 they started publishing D6 Space, a generic area opera online game system based on the previous celebrity Wars: The Roleplaying Game, yet not including specific celebrity Wars content.


text:
Palestine Post
From Wikipedia, the free encyclopedia
For the newspaper The Palestine Post (1932–1950), see The Jerusalem Post.
|البريد الفلسطيني
Palestine Post
|Government Department overview
|al-Bireh, West Bank
|Government Department executive
|Parent Government Department
|Ministry of Transport
Palestine Post is the company responsible for postal service in the parts of Palestinian territories controlled by the State of Palestine.[1]
See also[edit]
- Postage stamps and postal history of the Palestinian National Authority
- Postage stamps and postal history of Palestine
External links[edit]
- ^ "Palestine Post". Palestine Post. Retrieved 2010-02-07.
|This Palestine-related article is a stub. You can help Wikipedia by expanding it.


text:
- Aa
- Aa
Cardello, Armand V. and Jaeger, Sara R. 2016. Emotion Measurement.
de Andrade, Juliana Cunha de Aguiar Sobral, Louise Ares, Gastón and Deliza, Rosires 2016. Understanding consumers' perception of lamb meat using free word association. Meat Science, Vol. 117, p. 68.
den Uijl, Louise C. Jager, Gerry Zandstra, Elizabeth H. de Graaf, Cees and Kremer, Stefanie 2016. Self-reported food-evoked emotions of younger adults, older normosmic adults, and older hyposmic adults as measured using the PrEmo2 tool and the Affect Grid. Food Quality and Preference, Vol. 51, p. 109.
Gmuer, Angelina Nuessli Guth, Jeannette Hartmann, Christina and Siegrist, Michael 2016. Effects of the degree of processing of insect ingredients in snacks on expected emotional experiences and willingness to eat. Food Quality and Preference, Vol. 54, p. 117.
Kremer, Stefanie and den Uijl, Louise 2016. Emotion Measurement.
Porcherot, C. Delplanque, S. Ferdenzi, C. Gaudreau, N. and Cayeux, I. 2016. Emotion Measurement.
Ruby, Matthew B. Alvarenga, Marle S. Rozin, Paul Kirby, Teri A. Richer, Eve and Rutsztein, Guillermina 2016. Attitudes toward beef and vegetarians in Argentina, Brazil, France, and the USA. Appetite, Vol. 96, p. 546.
Vidal, Leticia Ares, Gastón and Jaeger, Sara R. 2016. Use of emoticon and emoji in tweets for food-related emotional expression. Food Quality and Preference, Vol. 49, p. 119.
Gmuer, A. Nuessli Guth, J. Runte, M. and Siegrist, M. 2015. From emotion to language: Application of a systematic, linguistic-based approach to design a food-associated emotion lexicon. Food Quality and Preference, Vol. 40, p. 77.
Köster, Egon P. and Mojet, Jozina 2015. From mood to food and from food to mood: A psychological perspective on the measurement of food-related emotions in consumer research. Food Research International, Vol. 76, p. 180.
Pellegrino, Robert Crandall, Philip G. and Seo, Han-Seok 2015. Hand washing and disgust response to handling different food stimuli between two different cultures. Food Research International, Vol. 76, p. 301.
Wardy, Wisdom Sae-Eaw, Amporn Sriwattana, Sujinda No, Hong Kyoon and Prinyawiwatkul, Witoon 2015. Assessing Consumer Emotional Responses in the Presence and Absence of Critical Quality Attributes: A Case Study with Chicken Eggs. Journal of Food Science, Vol. 80, Issue. 7, p. S1574.
Coleman, Katie L. Miah, Emma M. Morris, Gordon A. and Morris, Cecile 2014. Impact of health claims in prebiotic-enriched breads on purchase intent, emotional response and product liking. International Journal of Food Sciences and Nutrition, Vol. 65, Issue. 2, p. 164.
den Uijl, Louise C. Jager, Gerry de Graaf, Cees Waddell, Jason and Kremer, Stefanie 2014. It is not just a meal, it is an emotional experience – A segmentation of older persons based on the emotions that they associate with mealtimes. Appetite, Vol. 83, p. 287.
Jiang, Y. King, J.M. and Prinyawiwatkul, W. 2014. A review of measurement and relationships between food, eating behavior and emotion. Trends in Food Science & Technology, Vol. 36, Issue. 1, p. 15.
Brown, Lorraine Edwards, John and Hartwell, Heather 2013. Eating and emotion: focusing on the lunchtime meal. British Food Journal, Vol. 115, Issue. 2, p. 196.
Edwards, John S.A. Hartwell, Heather J. and Brown, Lorraine 2013. The relationship between emotions, food consumption and meal acceptability when eating out of the home. Food Quality and Preference, Vol. 30, Issue. 1, p. 22.
Jaeger, Sara R. Cardello, Armand V. and Schutz, Howard G. 2013. Emotion questionnaires: A consumer-centric perspective. Food Quality and Preference, Vol. 30, Issue. 2, p. 229.
Ng, M. Chaya, C. and Hort, J. 2013. Beyond liking: Comparing the measurement of emotional response using EsSense Profile and consumer defined check-all-that-apply methodologies. Food Quality and Preference, Vol. 28, Issue. 1, p. 193.
Barthomeuf, Laetitia Droit-Volet, Sylvie and Rousset, Sylvie 2012. How emotions expressed by adults' faces affect the desire to eat liked and disliked foods in children compared to adults. British Journal of Developmental Psychology, Vol. 30, Issue. 2, p. 253.
Eating behaviour depends partly on food preference, which is itself determined by different types of emotions. Among the emotions generated by food, disgust with red meat is common in women and can lead to reduced meat consumption. We tested the hypothesis that low meat intake is related to different negative emotions towards meat but does not affect the emotions expressed towards other food categories. Food intake of sixty women was followed throughout each day for 1 week and allowed us to assign women to two groups (low v. high meat-eating women). They were then invited to assess the intensity of twenty-six emotions described by words and induced by thirty food pictures. We determined the number of necessary dimensions to describe the space created by the twenty-six words. The results showed differences in emotions between the low and high meat-eating women. As expected, there were overall differences in the emotions generated by the thirty food pictures. Six clusters of emotions were necessary and sufficient to summarise the emotional space. These dimensions were described by 'disappointment', 'satisfaction', 'guilt', 'doubt', 'amused' and 'indifference'. As expected, the low meat-eating women felt more 'disappointment', 'indifference' and less 'satisfaction' towards meat than did the high meat-eating women. However, the low meat-eating women also stated other negative emotions such as 'doubt' towards some starchy foods. The only foods that they liked more than high meat-eating women were pears and French beans. In conclusion, low meat consumption was associated with specific negative emotions regarding meat and other foods.
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text:
Welcome to MSathlete!
Help us stop the degradation of our community.
The MS Society of Canada will be:
1) selling MS Centre in Victoria, a place that many of us call home
2) discontinuing the MS Physiotherapy Program, the only of its kind in Canada and
3) disbursing programs and services to other unknown locations or online
Many of us who live with MS every day and use this centre see this as a cruel and hurtful action. Please join us in the protest and let your voice be heard by adding your comments.
- MS Society increases top salaries by 50% and drops programs for people with MS
- My letter to Ms. Joseph, Board Member, MS Society Research Foundation
- Help me understand how 1+1 = 2+1: an open letter to the Treasurer of the MS Society of Canada
- Open Letter to Rahil Dattu, Board Member, MS Society of Canada
- Here's who made the decision to sell our MS Centre
- An open letter to the MS Society of Canada regarding your degradation of our community
- MS Society response to open letter regarding their degradation of our community
- Top 5 reasons MS Society of Canada shouldn't use their survey results to make decisions
- Letter to Minister of Health regarding services delivered to citizens living with Multiple Sclerosis
This years MSAthlete swims:
Please visit the sites to learn more!
An Open Letter to the City of Victoria Regarding the Future of Crystal Pool
I have recently become aware that you will soon be making a decision regarding the future of Crystal Pool. Before you make that decision I would like to share my thoughts on this matter with the hope that you will take them into consideration. Read more.
70km swim for MS
- part 1 – how to blow your shoulder before a big swim
- part 2 – mental gymnastics
- part 3 – a beautiful start
- part 4 – into the night
- part 5 – pushing through the last 25km
MS Philosophy: there is no such thing as a failed attempt
Every day when I wake up I think about how lucky I am that I was raised to try new things. In many was this is what makes it possible for me to live a productive life with multiple sclerosis.
MS Addiction: got dope?
There are over seventy-five drugs many of us have been prescribed for our Multiple Sclerosis. My drug of choice – dopamine – and I regularly self-medicate.
Multiple Sclerosis in the Raw – a natural state of being I find myself thinking a lot these days. Thinking about Multiple Sclerosis and if I am doing the right things to manage my disease. Not just manage it to the point of being "ok," – I want to be more than that.