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Frames and Search Engines
Is it true that using frames makes it harder for search engines to properly index my site?
Yes. Using frames in your website design makes it harder for search engines to properly index your site. In fact, in the early days of search, Inktomi and AltaVista simply wouldn't index your framed site at all.
A typical framed Web page is made up of three or more files instead of the standard one file that makes up non-framed Web pages. In a typical framed Web page, there are one or more files for the main body content, one or more files for the navigation, and one main file to stitch the other two or more files together into a Web page (the assembler frame). The illustration below shows a simple framed site, demonstrating how frames work together to create separate parts of a web page, which are then sewn together by the main assembler frame page. Put your mouse over the different parts of the image for a detailed explanation.
In the picture above the Main Frame (or assembler) is one HTML file, the Navigation Frame is a second HTML file, and the Content Frame is a third HTML file (these need not be HTML files). When a someone visits your site, they are presented with the Main Frame (or assembler) which they download into their Web browser. Their browser reads the code in that file and then sends a second and third request back to your server for the two additional files. Once the additional files are received, the visitor's browser assembles the page.
When a search engine spider visits your framed Web page, it also sees the Main Frame (assembler) file, which is used to stitch the frames together. Unfortunately, the links from the main frame page (the stitching page) to the included frames pages (the body and navigation pages) are created using SRC links instead of HREF links. Inktomi and AltaVista will not follow those. So all Inktomi and AltaVista will see is the code you use to assemble your frame pages, not your content or navigation. There is a workaround involving the use of the <NOFRAMES> tag, but then you have to maintain two versions of your website, one version spread out throughout your Content Files and one version included in your Main Frame files. That means editing your content twice for each change you make to any text on your site.
Google will follow your assembler page SRC links, but that's not good news for you. Because your Content Frames don't have any of your navigation in them (you pulled it all out to place in your Navigation Frame), the people who visit your page will see your content but without your site navigation. That's a usability nightmare. There is a workaround for this issue as well, but it adds even more usability problems for your site, as it involves redirecting your visitor to multiple assembler pages when they land on your content pages from the search engines.
What the search engines say about frames and websites
The Inktomi spider, known as "Slurp, " cannot follow SRC links in framed sites. The AltaVista spider also cannot follow SRC links in framed sites. From: Inktomi - Slurp.
"Following links: Slurp follows HREF links. It does not follow SRC links. This means that Slurp does not retrieve or index individual frames referred to by SRC links." From: AltaVista - Help - FAQ - Adding & Removing URLs
"12. What types of Web pages does AltaVista not index?
AltaVista's crawler does not index the following types of content: ...
Information inside frames; AltaVista indexes the outside of the frame as a distinct page, so you should have non-frames as well as frames versions of your Web pages, and submit the non-frames versions via our Basic Submit or Express Inclusion services."
Solutions for Framed websites
Don't use frames in Web design.
Jakob Nielsen summed up many of the best reasons not to use frames way back in 1996. You can read why frames constitute on of the top ten mistakes in Web design on his site.
The <NOFRAMES> Tag Workaround.
One way around the problem is to use the <NOFRAMES> tag. This tag shows the search engines what they missed by refusing to follow the SRC links. Basically, you copy the content from your included body and navigation frames into the main frame page, including them between <NOFRAMES> and </NOFRAMES>. By putting your navigation and your home page content into the <NOFRAMES> part of your Main Frame, you are enabling the spiders to see what the visitor would see when visiting your site. You are also enabling the spiders to follow your links to the other content pages on your site. Unfortunately, your content pages don't contain your navigation because you've put that in your Navigation File. So, your visitors will see your content, but they won't see any of your main navigation links, leaving them stranded at a dead end or forced to follow the links you've included in your content. Another issue is the fact that many people who use framed sites put their corporate identity material in one frame to keep it at the top of the page at all times. Search engine visitors who visit your content pages will not be able to see your corporate identity material (site name, header, and logo) if you do this.
There is a workaround for this issue as well, but it involves putting code on each of your content frame pages that redirects visitors to your main frame page when they visit one of your content frames directly from a search engine. If you have just one Main Frame page, then all your search engine visitors will automatically be redirected to your home page. They won't like that. You will have to build a unique Main Frame page for every page of your website if you want your visitors to be redirected to the page they intended to visit. Then you can use a Java redirect script that is unique on each content page. The script will check to make sure that the content page was loaded by a Main Frame page, and if not, will reload the browser using a Main Frame page so that the visitor sees the navigation and content.
In the end, you will improve your user's experience with your site and cut down on your maintenance time by simply removing the frames outright so that the search engines can see your content as your visitors are intended to see it.


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Hotels near Hamilton Hall
Booking multiple rooms?
Visit our group bookings page or call 020 7437 4370 for assistance
Room 1
Most popular hotels near Hamilton Hall
London > Hotels > Mid-Range Chain Hotel from £120 35% off
3 South Place, EC2M 2AF | 1 minute walk from Hamilton Hall
Located within arms reach of both Moorgate and Liverpool Street stations, is South Place Hotel, a luxury London hotel featuring three swanky bars and two top-notch More
London > Hotels > Luxury Chain Hotel from £120 28% off
40 Liverpool Street, EC2M 7QN | 2 minutes walk from Hamilton Hall
Housed in one of the great Victorian station hotels, this showstopper is a mixture of meticulous nineteenth century restoration and the glittering wit of Terence Conran's More
London > Hotels > Apartment from £87 26% off
196 Bishopsgate, EC2M 4NR | 2 minutes walk from Hamilton Hall
From studio apartments to one and two beds, 196 Bishopsgate offers a full range of self-catering flats that give you more independence than a hotel. Apartments More
Find other hotels near Hamilton Hall
Hotels near Hamilton Hall
Hamilton Hall
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Top rated hotels near Hamilton Hall
Previous customers have given the highest customer satisfaction score to these five hotels near to Hamilton Hall:
Apex London Wall Hotel
Customer rating: 96%
7 minutes walk away
Double room from £191
South Place Hotel
Customer rating: 94%
1 minutes walk away
Double room from £230
196 Bishopsgate Serviced Apartments
Customer rating: 93%
2 minutes walk away
Double room from £224
Threadneedles, Marriott Autograph Collection
Customer rating: 92%
7 minutes walk away
Double room from £217
Andaz Liverpool Street Hotel
Customer rating: 90%
2 minutes walk away
Double room from £299
Nearest hotels to Hamilton Hall
There are 14 recommended places to stay within a 15 minutes walk from Hamilton Hall:
South Place Hotel ( 1 minutes)
196 Bishopsgate Serviced Apartments ( 2 minutes)
Andaz Liverpool Street Hotel ( 2 minutes)
Apex London Wall Hotel ( 7 minutes)
Threadneedles, Marriott Autograph Collection ( 7 minutes)
Club Quarters Gracechurch ( 9 minutes)
Ace Hotel London Shoreditch ( 10 minutes)
Holiday Inn Express London-City ( 10 minutes)
Courthouse Hotel Shoreditch ( 11 minutes)
DoubleTree by Hilton Tower of London ( 11 minutes)
Grange City Hotel London ( 11 minutes)
Apex City of London Hotel ( 12 minutes)
Grange Tower Bridge Hotel ( 13 minutes)
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subset: commoncrawl


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Otolaryngologist (ear, nose, throat)
179 Washington Ln
Jenkintown, PA 19046 Phone number & directions
179 Washington Ln
Jenkintown, PA 19046 Phone number & directions
License & Identifications
A medical license is required for a doctor to practice medicine in a particular state. Requirements vary by state but most require, at a minimum, post-graduate training in the doctor's specific specialty. An NPI number is a national identifier unique to an individual health care provider and is managed by the Center for Medicare & Medicaid Services (CMS).
Learn more about Dr. Louis Welsh:
View the full profile to get information on:
- Qualifications
- What's important to you
View full profile
Patient Reviews
Have you visited Dr. Welsh? Share your experience.
Write a Review
Write a Review
Prepare before visiting Dr. Welsh
Face Lift Patient Education Read about facial cosmetic surgery treatments in our face lift patient education guide.Before Visiting Dr. Welsh Learn More
|More Patient Guides & Topics
Home Allergies
Seasonal Allergies
Specialties & Research
Dr. Louis Welsh, MD is board certified in Otolaryngology.
- He has special expertise in 6 areas:
- Deafness
- Hearing Disorders
- Psychoanalysis
- Psychotherapy
- Throat Cancer (Laryngeal Neoplasm)
- Vertigo
Education & Awards
Dr. Welsh graduated from Drexel University , Philadelphia.
Home > Find an Otolaryngologist > PA > Jenkintown Otolaryngologists > Dr. Louis Welsh, MD
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- Additional Information
- Dr. Louis Ward Welsh MD is a male Otolaryngologist and practices in Otolaryngology.
- Where does Dr. Louis W. Welsh practice?
- Dr. Louis Welsh has 1 office location.
Dr. Louis Welsh practices Otolaryngology near Jenkintown, PA.
See Jenkintown Otolaryngologists.


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- 2 years of Retail Marketing and/or Merchandiser
- Bachelor's Degree in Marketing, Business Admin
- Good communication and negotiation skill
Salary negotiable
- Bachelor's Degree in any field.
- experience of working in the ELT publishing
- Have car and car driving license.
- Experience in FMCG sales preferable.
- Knowledge of sales fundamentals.
- Good Business English, computer literacy.
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Spacious 2 Bedroom
Спальные места4
Ванные комнаты1
Площадь900 фут² (~0,1 м²)
Этаж №
- Интернет
- Кухня
- Кондиционер
- Полотенца
|48 ave, 11373 New York, США
|Тип жилья
|ID жилья
|Процент подтвержденных запросов брони
|Время ответа
|Несколько часов
|Календарь обновлен
|Несколько месяцев назад
|Цена за неделю
|59374 руб.
|Цена за месяц
|185667 руб.
|Заезд после
|Заселение до
|По договоренности
|Отъезд до
|Политика Отмены Брони
Jason was very friendly and dedicated. The room was clean and looked like on the fotos. It was a nice stay. We would always come back again.
Our stay in te apartment was really comfortable, Jason was waiting for us upon our arrival and gave us all the directions needed to have a pleasant stay.
The apartment was exactly the same as in the pictures, nice and clean.
I would definitely recommend Jason's apartment for a nice stay in NYC.
This place is wonderful! Jason is an excellent host, very kind and attentive. The apartment / neighbourhood is very safe and clean, with all the things you can need. We recommend Jason´s properties to everyone!
Thank you, Jason, we felt as if we were at home! :-)
I stayed with 7 friends in the Modern Duplex posted by Jason. The photos shown on the site are accurate to where we stayed. The place was immaculate and very close to the subway station. Perfect !
The neighborhood is very safe and clean. A plus to the neighborhood is that there is a Target and Century 21 close by. There are 2 diners close to the apartment that are opened to 2 a.m. and 24hrs.
As a host, Jason was incredibly accommodating. He is very nice, punctual and very attentive. He drove me around the neighborhood to show me every point of interest. He made himself available had I needed his assistance with anything.
I recommend Jason's properties. I travel to NYC twice a year during which I stay for a month each time. I will book with him every time. I have also referred Jason to a few friends who have had similar a experience.
Our stay at Jason's was the best experience we have had through Wimdu. He is extremely helpful and the apartment is spotless clean.
Jason's can be recommended for everyone!
We had a very pleasant stay in Jason's appartment. The appartment is located in a quiet street but is near the lively Elmhurst avenue with a lot of Asian shops and restaurants and a direct connection to Manhattan. Jason is very nice and helpful. The appartment has all the necessary equipment.
It's a very nice location.
Jason, the landlord, was very kind and helpful.
There was a fast WLAN, and a PC.
Apartment was very nice and cosy. And the neighborhood felt safe. Host Jason was so warm and friendly person! He was helpfull and caring. We definitely recommend!!! Thank you Jason!
Jason's room is lovely, very conveniently located in a great neighborhood in Queen with easy access to Manhattan.The room itself is great, very clean, comfy beds, with nice kitchen, bathroom and wifi.
Jason himself was very helpful when we were late arriving, very easy to get in touch with as well. In short, we loved our stay at his place and highly recommend it!
My host Jason was adorable and available. Gave me all info and actually, showed me the quiet and nice neighborhood and where there are shops and something to enjoy for food.
The studio is beautiful, super big and lacks nothing, very clean, towels has galore, great bed, computer available.
Metro very loan that goes all directions, JFK airport by subway and AirTrain, very easy.
I had a great time in NY and would stay in Queens. Thanks Jason and see you very soon.
- Гарантировать качество жилья
- Проверить каждого принимающиего Вас хозяина по телефону
- Обеспечить безопасную оплату через шифрование на базе SSL


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Huawei Technologies
Huawei is a global leader of ICT solutions. Our telecom network equipment, IT products and solutions, and smart devices are used in 170 countries and regions. Huawei ranked 285th on the Global Fortune 500 in 2014. We invest over 10% of our annual sales revenue into R&D and more than 45% of our 150,000 employees engage in R&D. We have built 16 R&D centers worldwide and 31 joint innovation centers with customers. our sales revenue reached USD 46.5 billion in 2014, an increase of over 20% year-on-year. The operating profit reached USD5.5 billion, a year on year increase of 12%.
Cloud Computing Is a significant opportunity for Huawei to achieve strategic transformation over the next ten years.Huawei's enterprise cloud was released in July,2015, Huawei is plannig to provide cloud services,including data protection,big data,database and etc.


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strategic communication
Quotable: Schoen and Lamb on interagency collaboration to refute Soviet disinformation
Wednesday, September 21st 2016
"This study explains how one part-time interagency committee established in the 1980s to counter Soviet disinformation effectively accomplished its mission. Interagency committees are commonly criticized as ineffective, but the Active Measures Working Group is a notable exception. The group successfully established and executed U.S. policy on responding to Soviet disinformation."
Headline: Deception, Disinformation, and Strategic Communications: How One Interagency Group Made a Major DifferenceRead More
Quotable: Peter Pomerantsev's dark analysis of a "post-fact" world
Sunday, August 28th 2016
"I remember facts seemed to be terribly important during the Cold War," wrote Legatum Institute senior fellow Peter Pomerantsev in a dark July 20, 2016, article, "Why We're Post-Fact," in Granta: The Magazine of New Writing. "Both Soviet Communists and Western Democratic Capitalists relied on facts to prove their ideology was right. The Communists especially cooked the books – but in the end they lost because they couldn't make their case any longer. When they were caught lying they acted outraged. It was important to be seen as accurate."
That was then. Now is now. Pomerantsev senses changes in basic thinking and how they bear on Public Diplomacy and strategic communication. Practitioners need to be aware, for instance, of the "equaling out of truth and falsehood," "disinformation cascades, "techno-fantasies," and "digital wildfires." Here are some highlights of his article:Read More
Public Diplomacy: Seen on the Web (V)
Sunday, August 14th 2016
These are abbreviated references to articles "seen on the web" relating to public affairs, Public Diplomacy, international broadcasting, and information operations, provided in this format to allow searches on this PDC website. They supplement the "Quotables" series. These articles are from January, 2016.
Read More
Quotable: Tony Selhorst on the role of information in the Gerasimov doctrine
Saturday, June 25th 2016
America's Public Diplomacy officers in the field – reports are unanimous – are overworked and under-resourced. Just tending the stable repertoire of Public Diplomacy programs – work with local media, publicity for the Ambassador and administration visitors, managing an Embassy's web presence, organizing exchanges, speakers and seminars, English teaching, American spaces, and so on – keeps American officers and their local staff winded.
The current turbulence and coming storms in international relations will provide no respite for Public Diplomacy. There will be challenges to every element of U.S. national power, especially the information element.
ISIS, Iran, China, and Russia are using their military – and information – power in new and disruptive ways. Modern communications and the social media have increased the velocity of conflict, outrunning traditional military and diplomatic communication, deliberation, and decisions.Read More
Quotable: Steve Tatham on using social science in response to Russian propaganda
Friday, June 17th 2016
"Whatever might be said about Russian foreign and military policy in Ukraine and the former soviet states, they cannot be accused of not taking Information Warfare seriously." Retired Royal Navy Commander Steve Tatham so opened his July, 2015, paper, "The Solution to Russian Propaganda is not EU or NATO Propaganda but Advanced Social Science to Understand and Mitigate its Effect in Targeted Populations," published by the National Defense Academy of Latvia.
The paper breaks into three parts. Tatham opened with a review of recent Russian initiatives, many astonishing in their audacity. He followed with a critique of NATO and Western counter-messaging (too often "crafted by European or North American men in suits sat behind a computer in an office") because it is not informed by social research on target audiences, and he closed with recommendations. His closing thoughts on risk were telling.Read More


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Play Video
Super mario en alejo y valentina.
Posted by alfic on Aug. 26, 2007
The new season of The Walking Dead is just around the corner, and after tha...
Hey Break fans! Check out our latest compilation, Car Crashes & Chaos Part ...
Learn everything you need to know about how to climb Mount Everest!
Posted by alfic on Aug. 26, 2007


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Do you have a kitchen or cooking secret that saves time, calories or clean up?
Download the free e-cookbook and show your child the joy of cooking. It offers healthy alternatives & ideas for parents & caregivers of children. http://www.peelregion.ca/health/obesity/resources/pdfs/cookbook.pdf
GLUTEN FREE OATS must be LABELLED Gluten Free This USES no MILK, is kid friendly,add raisins, nuts, craisins, cinnamon . apple sauce .
For I SERVING 1/3 cup of quick oatmeal or steel cut oats
2/3 cups unsweetened Apple juice or OJ is good too.
Microwave in Micro pan or in high sided bowl ...
I'm making a Birthday cake for my bowling team and I have to make icing and of course I have to try it to make sure it is okay. My mouth taste sicking sweet. I don't eat a lot of sweets and I don't use sugar on things so you can see why.
A splash of almond oil instead of olive oil when sauteeing adds a great hint of flavour to many meats and veggies.
I sometime use crushed pork rinds and sesame seeds as a low-carb substitute for breading chicken. Gives a smokey flavor. Try the bar-b-que flavored too.
I have learned to eat egg whites or egg white substitutes along with shrimp as my primary protein sources because they are so low in calories--more bang for my buck!
I will make Milanese Fettucine Alfredo today with Saffron sauce. Cannot wait! :)
quick dinner
I like to take a regular recipe and reduce the fat and sugar, and/or substitute w/ no calorie sweetner.
On a few weekends I cook a few "large" meals. We than measure them ie a cup of chilli, put them in vacuum bags and freeze. They stay fresh for an extended period of time with the vacuum bags, we always have a variety on hand to take for lunch or for a quick dinner when we don't feel like cooking


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Come Create With Us!
Welcome to the Art Room! We are a small art studio in Lafayette, CA that has an emphasis on small classes with strong individual attention. Whether students are creating one of our unique projects or a still life that we've set up, the results are amazing. With the guidance provided by skilled art instructors, students gain self-confidence as they explore and develop their artistic ability. In addition to the wide variety of classes we offer, we host birthday parties and events, have creative workshops, and seasonal day camps. We provide a positive and nurturing learning experience that encourages our students to use their imagination. Students begin to acquire an art vocabulary, are introduced to well known artists, and learn the necessary skills to create great art.
Important Dates to RemembeR
- Our 13 week fall session begins September 12 and ends the week of December 12 (there will be class that week)
- We will be closed October 31 for Halloween
- We will be closed November 11 in observance of Veterans Day
- There will be no class the week of Thanksgiving break, but checkout our Autumn Camp that week!
- Winter Camp will be December 19-23, sign up for our newsletter to get updates!
Kid classes
Explore our classes for all ages that feature drawing, painting, graffiti, clay, sculpting, watercolor, mixed media, collage, photography, animation, and so much more!
We offer classes for artists of all ages and levels of experience. Master new drawing and painting techniques or create with clay!


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When added to the mash, this combination of buffer salts keeps the mash pH at 5.2—regardless of the pH of your brewing water. Use at a rate of 1 tablespoon per 5 gallons of water.
Seven Bridges Organic
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Very nice picture Graham and a very nice collection!
Greetings from Norway!
I'm going through my collection looking for people who have been kind enough to comment on pictures and who I never replied to - thank-you for your encouragement - at least i have an excuse for looking through your lovely collection again. Graham
Thanks Graham for all your beautiful pictures, especially those from South Africa. Another greeting from Norway.
thank-you so much for your kind words havis - as I can see you understand, the greatest pleasure is seeing these beautiful parts of our world, and the second is the privilege of being able to share what you see :)
Very beautiful place ,nice landscape,greetings from Brazil,Luciano.
thank-you Luciano - a real oasis in the dry Karoo - a lovely spot - and a nice farm guest house, too :)
Sign in to comment.
Photo taken in Graaff-Reinet, South Africa


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Rebecca Gethings
Warm clear friendly voice with a standard English accent. Capable of many different dialects and Character voices. Good Southern Irish Accent
English, English (North American), English (British), English (Australian), English (New Zealand)
Australian, British, Eastern European, England - North West (Liverpool, Manchester, Lancashire, Cheshire), Irish, Irish Northern (Ulster, Belfast), Italian, Italian American, New Zealand, North American, South African (Afrikaans), US South (Deep South, Dixie, Delta)
Special Skills
Audiobooks, Business, Cartoons, Documentaries, Educational, Internet, Jingles, Movie Trailers, Music, Podcasting, Radio, Telephone, Television, Videogames
Payment Terms
Hire Rebecca as a voice actor. Payment is made through Voices.com SurePay, an escrow service that guarantees your work is done to your satisfaction. Send payment securely by Visa, Mastercard or PayPal through Voices.com then download your files from the website.
Watch a video to see how to make a payment
Next Steps
To contact Rebecca Gethings about your project, request a quote today. We'll walk you through the process step-by-step. It's fast and easy.
Commercial spot Body shop Irish accent 135 Listens
corporate narration 26 Listens
Rebecca Gethings Character Voice Commercial Spot 107 Listens
British Accent On-hold Corporate Narration 11 Listens
RP character AND Irish commercial 114 Listens
Soft Sell/ Sexy commercial Spot 20 Listens
Hire Rebecca Gethings as a voice actor. Working with Rebecca Gethings is fast and easy. We'll walk you through the process step-by-step.
Request a quote for your project today.


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On the 512th day of his presidency, Barack Obama used his first Oval Office address to try and allay the nation's fears about the countless barrels of oil currently spilling into the Gulf of Mexico, what he termed the "worst environmental disaster" in American history. Though the president prefaced things by saying he intended to "lay out … our battle plan," actually, aside from a few minor details most everyone already knew, the speech was vague and defensive at best, ill-informed at worst. Overall, it should have left viewers sure of only one thing: everyone's still stumped.
Though he did offer up jargon like "skimming" and "boom," and references to the tens of thousands of men and women working to contain the spill, most of Obama's best rhetorical advances tonight were almost immediately undermined by timid lines like "these efforts should capture up to 90 percent of the oil leaking out of the well," weak proclamations that won't win any votes of confidence from the increasingly disappointed American people. Nor will the president's assurance that "scientists and experts … have provided ideas and advice." As we all well know by now, ideas and advice are fine, but they won't necessarily stop the deluge of fossil fuels currently darkening our nation's coastlines. And to the shrimpers and oystermen out of work in Louisiana and Mississippi and Alabama tonight, ideas and advice that don't plug that hole are as useless as millions of gallons of oil floating off into the sea.
What we needed tonight was a leader with a solid vision for not only how to get out of our current predicament but also how to resolve our nation's energy crisis in the long term. What we got was a president who seemed unaware of what was happening in important government offices and stunned that oil executives would deceive him in order to advance their agendas in our oceans:
A few months ago, I approved a proposal to consider new, limited offshore drilling under the assurance that it would be absolutely safe — that the proper technology would be in place and the necessary precautions would be taken. That was obviously not the case on the Deepwater Horizon rig, and I want to know why.
Perhaps the most interesting passage of Obama's speech came toward the end, when he declared, "[T]he House of Representatives [passed] a strong and comprehensive energy and climate bill — a bill that finally makes clean energy the profitable kind of energy for America's businesses." While that is true, what the president failed to mention is that that bill is now stalled in the Senate with little to no forward momentum. That Obama omitted that hugely important detail ostensibly means that his administration is willing to tell citizens half-truths if it will make them at least a little less worried about the Gulf and our nation's unyielding addiction to oil.
Considering the crushing uncertainty of tonight's speech, it's no wonder, then, that the president ended it by saying he "[prays] that a hand may guide us through the storm towards a brighter day." The only problem is that God can't stop the leak.
The transcript:
Good evening. As we speak, our nation faces a multitude of challenges. At home, our top priority is to recover and rebuild from a recession that has touched the lives of nearly every American. Abroad, our brave men and women in uniform are taking the fight to al Qaeda wherever it exists. And tonight, I've returned from a trip to the Gulf Coast to speak with you about the battle we're waging against an oil spill that is assaulting our shores and our citizens.
On April 20th, an explosion ripped through BP's Deepwater Horizon drilling rig, about 40 miles off the coast of Louisiana. Eleven workers lost their lives. Seventeen others were injured. And soon, nearly a mile beneath the surface of the ocean, oil began spewing into the water.
Because there has never been a leak of this size at this depth, stopping it has tested the limits of human technology. That is why just after the rig sank, I assembled a team of our nation's best scientists and engineers to tackle this challenge — a team led by Dr. Steven Chu, a Nobel Prize-winning physicist and our nation's Secretary of Energy. Scientists at our national labs and experts from academia and other oil companies have also provided ideas and advice.
As a result of these efforts, we have directed BP to mobilize additional equipment and technology. In the coming days and weeks, these efforts should capture up to 90 percent of the oil leaking out of the well. This is until the company finishes drilling a relief well later in the summer that is expected to stop the leak completely.
Already, this oil spill is the worst environmental disaster America has ever faced. And unlike an earthquake or a hurricane, it is not a single event that does its damage in a matter of minutes or days. The millions of gallons of oil that have spilled into the Gulf of Mexico are more like an epidemic, one that we will be fighting for months and even years.
But make no mistake: We will fight this spill with everything we've got for as long it takes. We will make BP pay for the damage their company has caused. And we will do whatever's necessary to help the Gulf Coast and its people recover from this tragedy.
Tonight I'd like to lay out for you what our battle plan is going forward: what we're doing to clean up the oil, what we're doing to help our neighbors in the Gulf, and what we're doing to make sure that a catastrophe like this never happens again.
First, the cleanup. From the very beginning of this crisis, the federal government has been in charge of the largest environmental cleanup effort in our nation's history — an effort led by Admiral Thad Allen, who has almost 40 years of experience responding to disasters. We now have nearly 30,000 personnel who are working across four states to contain and cleanup the oil. Thousands of ships and other vessels are responding in the Gulf. And I have authorized the deployment of over 17,000 National Guard members along the coast. These servicemen and women are ready to help stop the oil from coming ashore, clean beaches, train response workers or even help with processing claims — and I urge the governors in the affected states to activate these troops as soon as possible.
Because of our efforts, millions of gallons of oil have already been removed from the water through burning, skimming and other collection methods. Over five and a half million feet of boom has been laid across the water to block and absorb the approaching oil. We have approved the construction of new barrier islands in Louisiana to try and stop the oil before it reaches the shore, and we are working with Alabama, Mississippi and Florida to implement creative approaches to their unique coastlines.


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Sevan Biçakci Women's Brown Bead Bracelet With Dagger Closure
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Exclusively Ours! A master of intaglio gem carving, Istanbul-based designer Sevan Biçakçi crafts modern Byzantine jewellery you'll wear, and treasure, forever. Sevan Biçakçi's rose gold textured bead bracelet secures with a white, brown- and yellow-diamond-embellished dagger closure. Gold, rose gold and oxidized silver dagger and rectangular clasp detailed with floral engravings; clasp underside detailed with signature dagger insignia in sterling silver, short strand of cable chain attached to dagger. Pear-shaped yellow and brown diamonds, white diamonds. 24k yellow gold, 10k rose gold, oxidized sterling silver. 31mm band width, 7.75" interior circumference (approximately). Push-lock dagger and loop closure. Color: brown
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text:
Spotify's Top 10 most streamed tracksOctober 19, 2016 Updated: October 19, 2016 10:23am
The following list represents the most streamed tracks on Spotify, based on the number of people who shared it divided by the number who listened to it, from Friday Oct. 7, to Thursday, Oct. 13, via Facebook, Tumblr, Twitter and Spotify.
To continue reading this story, you will need to be a digital subscriber to HoustonChronicle.com.
AP: Copyright 2014 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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We loved this deal too, but it's no longer available. Check out our other fresh deals here.
Doubtless Bay Lodge - Northland
$125 for Two Nights for Two People incl. Full Breakfast Both Mornings at Doubtless Bay Lodge (value $250)
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- Take in the incredible sights surrounding Coopers Beach.
- Grab two nights for two people including full breakfast on both mornings at Doubtless Bay Lodge for $125.
- Explore the gorgeous beach only 800 metres from your accommodation.
- Start your day off with a delicious breakfast and prepare to use up a lot of energy.
- Affordable and exciting location for the whole family or a relaxing getaway by the seaside for a bit of romance.
In the 18th century Captain Cook and his merry crew were navigating their way around New Zealand when they sailed past a gorgeous bay. Upon viewing the entrance of the area, Cook entered into his journal "doubtless a bay". This is how the name of popular Northland destination, Doubtless Bay came about, soon becoming an historic port along with the surrounding Manganui town. It wasn't long after that the port was packed with whalers, missionaries and settlers who built the town which you can see today.
You can explore this historic area and the many amazing locations close to it, by grabbing two nights for two people, including full breakfast on both mornings, for only $125.
Steal a special someone away for a few nights and relax in a comfortable room at Doubtless Bay Lodge. You'll love the cosy atmosphere and revel in being so close to the beach and many other amazing sites like the Karikari Peninsula and the Okahu Estate Vineyard and Winery. Dig into a warm breakfast each morning out on the deck then head out for a day of adventure. Coopers Beach is the perfect place to take a dip and relax underneath the many Pohutukawa trees with your loved one or friends.
If you're in the mood for peace and quiet, then relax in your room and make use of the tea and coffee making facilities and cable television. And if you get a tad hungry, discover the best fish and chips in New Zealand at the famous Mangonui fish shop. So snatch up this deal now and take time out from the hustle and bustle of daily life at the ultimate holiday destination.
Doubtless Bay Lodge - Northland
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Latest mock draft pick
Hockey's Future is the latest to weigh in with its mock draft pick for the Ducks, and their final answer is. ...
Center Louis Leblanc of the Omaha Lancers in the Junior A United States Hockey League. The 6-foot, 178-pound Leblanc had 28 goals and 31 assists with 78 penalty minutes in 60 games in 2008-09.
If you're keeping track of mock drafts, the ones we've posted have the Ducks taking either a Russian defenseman, a Scott Niedermayer-type-defenseman or a forward from the WHL or U.S. National Development team with their 15th pick.
All that's missing now is a goaltender to round out the mocking.
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Comment Re:Inside (Score 1) 100
The thing would flop around on the table until solved.
I think it would require a larger cube ( like the coffee table style novelty cube ) or some seriously small steppers.
That would be a good prank cube. Build it and don't tell anyone. Let someone solve it. At 2:00am it will secretly scramble itself. Hilarity ensues. Paul Rose ( the silent one in the video ).


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Receive e-mail notifications when properties meeting your search criteria come onto the market!
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|Publication number
|Publication type
|Application number
|Publication date
|Apr 17, 2012
|Filing date
|Oct 28, 2005
|Priority date
|Oct 28, 2005
|Fee status
|Also published as
|Publication number
|Robert A. Kramp
|Original Assignee
|The Boeing Company
|Export Citation
|BiBTeX, EndNote, RefMan
|Patent Citations (13), Referenced by (2), Classifications (10), Legal Events (2)
|External Links: USPTO, USPTO Assignment, Espacenet
This invention relates generally to systems and methods for registering and avoiding flaws or splices in rolls of tape, and more specifically, to systems and methods for registering flaws or splices in composite tapes during manufacturing of composite structures.
Composite structures are commonly manufactured by progressively building up the structure with a plurality of layers of thin composite tape (or tow) laid one layer upon another. Typically, the operation begins by laying one or more tapes onto a starting template or tool that has a configuration generally corresponding to the desired shape of the article to be produced. A tape placement head of a manufacturing system moves over the surface of the template, guiding the one or more tapes of composite material onto the template. The head usually makes repeated passes over the template in a defined pattern until the composite material is entirely collated, building up successive layers of the composite tape to form the desired workpiece. A compaction roller (or other suitable presser device) is typically used for pressing the tape against the workpiece, thereby facilitating adhesion of the successive layers. The workpiece may then be subjected to a curing process (e.g. heating) to further adhere and bond the composite layers. Conventional systems for forming composite structures using successive layers of tape include those systems disclosed, for example, in U.S. Pat. No. 6,799,619 B2 issued to Holmes et al., and U.S. Pat. No. 6,871,684 B2 issued to Engelbart et al.
Composite tape rolls provided for forming composite structures may contain defective material or tape splices where defective material has been removed by the tape manufacturer. These splices can result in random and unpredictable process interruptions during lay up by a composite tape laying machine, causing down time during which the spliced section of the tape must be removed from the composite structure being manufactured. Additionally, reaching the end the tape roll unexpectedly can cause similar problems. To avoid tape flaws, splices, and roll ends, flaw avoidance systems typically use data provided by tape manufacturers that indicates the location of splices or flaws and roll ends to scrap lengths of tape that contain the splices or flaws, or to stop the process in the case of reaching a roll end. In these systems all such location data are referenced to the tape end at the leader of the tape roll.
Although desirable results have been achieved using such prior art systems, there may be room for improvement. For example, tape length can be lost and become unaccounted for by the flaw avoidance system. This results in a loss of the measuring reference to the starting end of the tape and the inability to avoid tape splices, flaws and/or roll ends until manual adjustments are made. However, these manual adjustments may be inaccurate and can contribute to further inability to avoid tape splices. Novel systems and methods that improve the tracking of tape splices by the flaw avoidance systems would therefore have utility.
The present invention is directed to systems and methods for avoidance of tape flaw, splices and roll ends in manufacturing, including the manufacturing of composite structures. Embodiments of systems and methods in accordance with the present invention may reduce the inaccuracies in referencing and tracking flaws, splices, and roll ends present in a tape, and may reduce downtime and associated costs, in comparison with the prior art.
In one embodiment of a method in accordance with the invention, during tape manufacture the location of the roll end is known and flaws or splices in a tape are detected. Markers are then provided on the composite tape or on the removable portion(s) of the tape as the tape is wound into a roll by a manufacturer. Each marker holds a parameter or set of parameters that indicates the location of one, or more flaws, or splices and/or the roll end relative to the marker. The markers are positioned in such a way that they are detectable prior to the unwinding of the tape to the flaw, splice or end of roll. During the use of such marked tapes for composite lay up, a tape is unwound and the parameter(s) held by each of the one or more markers is detected. A distance from each marker to the flaw(s), splice(s) and/or roll end is obtained from each parameter. This distance is then compared to the length of a tape course to be laid. If the distance from a marker to a flaw, splice, or roll end is shorter than the length of the tape course to be laid, the flaw or splice is avoided by scrapping the tape at least to a marker beyond a flaw or splice, or the process may be stopped (e.g. in the case of encountering the end of a roll). In a particular embodiment, an alternate tape course that is shorter than the distance between the marker and the flaw, splice or end of roll can be laid before the tape is scrapped to avoid a flaw or splice. In another embodiment of the invention, the markers used to indicate the location of flaws, splices or the roll end are provided on a removable part(s) of the tape. In an additional aspect of the invention, one or more markers are placed at a distance from the flaw or splice that is greater than the longest required tape course used in the manufacture of a part.
In an alternate embodiment, a method of applying a tape onto a workpiece includes feeding the tape from a tape supply using a tape application assembly, and applying the tape onto the workpiece using the tape application assembly. Simultaneously with the feeding of the tape, the tape is monitored for a marker indicating a defect within the tape or the end of the roll, the marker being spaced apart along the tape from the defect or roll end such that the marker arrives prior to the defect or roll end. The method further includes detecting the marker, and avoiding the application of a portion of the tape that includes the defect onto the workpiece or where the end of roll would be encountered before reaching the end of the length of a course of tape.
Embodiments of the present invention are described in detail below with reference to the following drawings.
The present invention relates to systems and methods for avoiding tape flaws or splices in manufacturing, and for encountering and avoiding the end of a tape roll within a partially completed course of tape, including manufacturing of composite structures. Many specific details of certain embodiments of the invention are set forth in the following description and in
Generally, embodiments of systems and methods in accordance with the present invention provide advance reference and tracking of tape flaws or splices as a tape is unwound during use for manufacturing. Thus, embodiments of the present invention may advantageously reduce the inaccuracies in referencing and tracking flaws or splices in a tape, and may improve efficiency and reduce costs associated with manufacturing components formed from composite tape.
As further shown in
In one specific embodiment, one or more markers 104 are placed at a distance from the flaw or splice 102 that is greater than a longest required tape course (e.g. a length of tape sufficient to wind one revolution around a mandrel, or the length of a forming tool, workpiece, or other suitable body or distance). This ensures that an adequate length of the tape 100 sufficient for any tape course is always available.
In some embodiments, the composite portion 201 has removable coverings on both sides (e.g. a backing paper on one side and a plastic film layer on the other side). In such cases, the markers 204 may be placed on any of these layers and portions. The markers 204 placed on the removable portion 203 can be detected by a sensor 208 during the application process as the tape 200 unwinds from a tape roll 205 and as the removable portion 203 is collected by a take up reel 206. The sensor 208 can be any suitable sensor for detecting markings, including, for example, a camera, a barcode reader/scanner, or any other suitable sensors. In other particular embodiments, such as the case of marking on the removable portion or portions, the sensor 208 may be chosen depending on the means of marking. For example, metallic tape could be used with metal sensing sensor, photoelectric and photographic sensors could be used for high contrast markers (e.g. black on white, barcode readers used with barcodes etc.). A common barcode or other standard coded marking format may advantageously allow more data to be carried and captured at high speed.
In yet another embodiment, a barcode, a data matrix or other similar coded mark that can contain more data than just a marker line may be applied to the removable part of the tape (e.g. backing paper). More specifically,
More specifically, as shown in a first table 360 in
Each marker 354 may advantageously provide a controller with an updated distance from it to the trailing end of the roll. The markers 354 (or barcodes) themselves would not need to contain the information about splice locations. Since one problem with prior art systems and methods is the fact that accurate reference to the splice location gets lost routinely, embodiments of the present invention may advantageously overcome this problem by providing an accurate position reference to the end of the roll that can be refreshed repeatedly by the reading marker (barcode) position data. Using embodiments of the invention, the flaw avoidance control software can otherwise be very similar to prior art systems and methods so development cost can be minimized. Less data may be required to be contained at each marking in this case and this may make finding a reliable code format easier. Each time that a barcode is read it would send the distance from it to trailing tape end position that is coded into it to the control. Splices/flaws locations would also be defined by their distance from the trailing end but entry of this data would be a separate operation from reading the barcode markings and making the tape position updates. An operator may only need to manually enter or automatically scan the flaw/splice data into the controller one time when the roll is first loaded or if it were reloaded on the tape laying machine. Having the information carried in the markers 354 (barcodes) throughout the length of the tape roll may advantageously allow the controller to find discrete positions within the tape roll with some accuracy.
Continuing on from decision block 408, if a splice was detected, the method 400 continues to block 412, where one or more markers is provided at a suitable distance from the splice (or other flaw). The marker(s) may be formed as the tape winds, or alternately, the winding of the tape may be temporarily suspended as the marker(s) is formed. The marker(s) indicates the location of the splice relative to the marker(s). At decision block 414, it is determined whether the desired numbers of markers have been provided. If the desired numbers of markers have not been provided, the method 400 loops back to block 412 to provide more markers. If all the desired markers have been provided, the method 400 loops back to decision block 404 to determine whether the tape roll is complete, and repeats the above-described actions until the tape roll is complete. Although the method 400 shown in
A distance from the flaw or splice to the marker is obtained from the marker at block 512. For example, as described above, different types of markers (e.g. different members of parallel lines) may indicate different distances to the next flaw or splice. At block 514, the distance from the flaw or splice to the marker is compared to the length of the next course to be laid, such as by a controller of an automated tape application machine. If the distance from the flaw or splice to the marker is not shorter than the length of the next course to be laid at decision block 516, then a tape course is laid at block 518, and the method 500 loops back to block 514 to compare the remaining length of tape to the length of the next course to be laid. This loop continues until the logical result of decision block 516 is "yes".
At decision block 516, if the distance to the next flaw or splice or end of roll is shorter than the length of the next course to be laid, then at an optional block 522, the method 500 may determine whether an alternate course in the same layer is available that is shorter than the length of tape available to the next splice or flaw, and if such an alternate course is available, then the tape may be applied along the alternate course at block 524. These optional actions (block 524, 522) may advantageously reduce the amount of tape that is scrapped, further reducing manufacturing costs.
As further shown in
It will be appreciated that in some circumstances, the markers for two flaw or splices may overlap, or in other words, the markers for one flaw may be placed so far ahead of it that the markers are actually placed in front of a preceding flaw. For example, depending upon the particular material specifications and anticipated tape courses in the manufacturing operation, the first marker may set a distance to the first flaw/splice, and if a second marker is detected before the first distance has elapsed, then control logic may be developed and programmed into the manufacturing controller to deal with such circumstances.
Embodiments of systems and methods for avoiding tape flaws or splices in manufacturing operations may be incorporated into a variety of different types of manufacturing systems. For example,
As further shown in
As shown in
In operation, as the head assemblies 610 are operated to apply the composite tape 615 onto the workpiece 642, the sensor units 660 monitor the tape 615 for the presence of markings. In one embodiment, the sensor units 660 determine whether a marking has been detected on the tape 615, and transmits an indicator signal to the machine controller 652. Alternately, the machine controller 652 may receive raw signals from the sensor units 660 and may perform the determination of whether a marking has been detected. The sensor units 660 (or the controller 652) may use a variety of suitable methods and algorithms for determining whether the markings are present on the tape 615.
Once a marking is detected on the tape 615, the system 600 may take appropriate action, as described above with respect to
In one embodiment, when the system 100 detects a flaw or splice marker, the control system 650 may do several things simultaneously (or sequentially): (1) set an operator accessible variable, called U-axis distance to splice position, to match the marker to flaw or splice distance; (2) turn a flaw/splice avoidance checking on, that is, turn on a control logical that begins performing the test that compares course length required by the part program to the distance to splice value; and (3) if no flaw or splices falls within the next course to be laid, continue the sequential lay up process, if a flaw or splice does fall within the length of next course to be laid, then the machine automatically executes a cycle to dispense the tape into the scrap area along the side of the tape laying machine.
In another embodiment of a tape laying machine with the flaw or splice avoidance system, the use of tape that is free from flaws or splices is maximized with further enhancements. Once a flaw marker is detected by the machine sensor, if the next control comparison of the distance to the flaw versus the next course length to be laid finds that a flaw or splice will be encountered within the length of the course, then the control software will initiate a search of the part program. The search will scan all course lengths remaining to be laid within the ply that is in work to find one or more courses of suitable length that can be laid down with the tape length that is available before the flaw or splice. The part program laying sequence would then be automatically reordered by the control to maximize use of tape that is available in front of the splice.
It will be appreciated that a variety of embodiments in accordance with the present invention may be conceived, and that the invention is not limited to the particular embodiments described above or shown in the accompanying figures. For example, letters, numbers, symbols, or other graphics, whether individually or in conjunction, may be used as markers to represent distances to flaws or splices. In one alternate embodiment, barcodes provided on the tape during winding may be used to indicate distances to flaws or splices during winding, and barcode readers may function as sensors to detect the markers during the unwinding of the tape for use.
Furthermore, embodiments of the invention may use a variety of technology to place markers on a composite tape. For example, an embodiment of the invention may use inkjet printing technology to label the tape with one or more markers during winding of the tape into a roll. However, other printing or labeling technology, such as laminating, embossing, stamping, or etching may be used to create markers on the tape. Moreover, although the disclosed embodiments have been described as being adapted to avoidance of tape flaws and splices in the manufacturing of composite structures, it may be appreciated that alternative embodiments of the invention may be used to improve other processes such as tape lamination or fiber placement.
While various embodiments of the invention have been illustrated and described above, many changes can be made without departing from the spirit and scope of the invention. Accordingly, the scope of the invention is not limited by the disclosure of these embodiments. Instead, the invention should be determined entirely by reference to the claims that follow.
|Cited Patent
|Filing date
|Publication date
|Mar 16, 1978
|Dec 4, 1979
|Oxford Industries, Inc.
|Creel loading and cutting system
|Oct 3, 1983
|Oct 15, 1985
|Dai Nippon Insatsu Kabushiki Kaisha
|Apparatus for affixing labels to moving web
|Jan 21, 1985
|Apr 15, 1986
|Gerber Scientific, Inc.
|Fabric flaw related system
|Feb 24, 1988
|Sep 19, 1989
|Filament winding system
|Oct 8, 1987
|Apr 10, 1990
|The Boeing Company
|Segmented tape shoe
|Jan 25, 1990
|Nov 20, 1990
|Krauss U. Reichert Gmbh & Co. Kg Spezialmaschinenfabrik
|Method and apparatus for recording a flaw in a fabric web
|Nov 2, 1994
|Feb 23, 1999
|Retech Aktiengesellschaft H. Von Arx
|Process for monitoring faults in textile webs
|Nov 11, 1997
|Sep 25, 2001
|Svante Bjork Ab
|Arrangement and method for marking defects
|Feb 18, 2000
|Apr 20, 2004
|Parsytec Computer Gmbh
|Method and appliance for detecting, identifying and relocating defects in a material strip
|Feb 6, 2002
|Oct 5, 2004
|The Boeing Company
|Composite material collation machine and associated method for high rate collation of composite materials
|Aug 13, 2002
|Mar 29, 2005
|The Boeing Company
|System for identifying defects in a composite structure
|Jul 1, 2002
|Jul 5, 2005
|Barvit Industrial, Llc
|Label application method
|Feb 6, 2002
|Aug 7, 2003
|The Boeing Company
|Composite material collation machine and associated method for high rate collation of composite materials
|Citing Patent
|Filing date
|Publication date
|May 9, 2012
|Apr 15, 2014
|The Boeing Company
|Mapping tow splices in composite structures
|Sep 27, 2007
|Apr 2, 2009
|The Boeing Company
|Optimized ordering of doubler plies in composite structures
|U.S. Classification
|427/427.2, 156/64
|International Classification
|Cooperative Classification
|European Classification
|Oct 28, 2005
Owner name: BOEING COMPANY, THE, ILLINOIS
Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:KRAMP, ROBERT A.;REEL/FRAME:017162/0993
Effective date: 20051028
|Oct 19, 2015
|Fee payment
Year of fee payment: 4


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Scores based on 105 reviews
Invoice history based on 86 reviews.
We are a family run business based in Hook, Chessington, and Surrey.
We undertake most types of electrical work. Our focus is mainly on domestic electrical installations, garden and garage projects. From adding an additional plug socket to a full re-wire, I hope we can help you.
We also provide PAT Testing services to domestic and commercial customers.
We will happily work in Surrey, Sussex and the Home Counties dependent upon the type of work requested.
Available via email and telephone 7 days a week.
Anywhere within reason!
A3 corridor
Home Counties


text:
2.5 star hotel
Area: The Downtown Loop
1.14 mi from TWA Museum
Best Rooms: The Comfort Inn is surrounded by a parking lot to one side and trees to the other. Thus rooms at the Inn offer little in terms of views.
4 star hotel
Area: Power and Light District
1.21 mi from TWA Museum
Best Rooms: Even-numbered rooms ending in *10 - *22 facing Baltimore Ave. offer a great view of the neighboring Kansas City Power and Light Building (e.g. 812, 1018, 1122); all other even-numbered rooms offer city views, better from floors 8 - 11, as rooms on floor 13 have smaller windows.
3.5 star hotel
Area: Northland, North Kansas City
3.09 mi from TWA Museum
Best Rooms: While the hotel is located next to the river, there are no real views of the river, as there are trees in the way.
4 star hotel
Area: Northland, Riverside
3.65 mi from TWA Museum
Best Rooms: Rooms facing south which are available in all categories, offer a good view of the river.
3 star hotel
Area: Southmoreland
4.59 mi from TWA Museum
Best Rooms: Located in a residential neighborhood, Best Western Plus Seville offers no real views because it's surrounded by the parking lot and other buildings.
2 star hotel
Area: Knoches Park
4.78 mi from TWA Museum
Best Rooms: There aren't any great views available, so your best option is to request a room facing the pool on any floor.
3 star hotel
Area: Plaza Westport
4.94 mi from TWA Museum
Best Rooms: Rooms ending in *07 and *10 - *16, on floors 3 - 6 (e.g. 307, 614), have the best views of Mill Creek Park and the surrounding city.
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|National Airline History Museum
|0.21 mi away
|City Market of Kansas City
|0.64 mi away
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|0.66 mi away
|Kansas City Convention Center
|1.14 mi away
|Sprint Center
|1.29 mi away
|Kauffman Center for the Performing Arts
|1.48 mi away
|Strawberry Hill Museum
|1.49 mi away
|St John the Baptist Catholic Church
|1.49 mi away
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|1.56 mi away
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|1.82 mi away
|North Kansas City, MO
|2.22 mi away
|5 hotels
|Merriam, KS
|8.63 mi away
|5 hotels


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13 June 2016
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The outlook for infrastructure private equity and venture industry - from the latest AltAssets' LP-GP Forum
David Valger, founder of DVO Real Estate, believes he has found a gap in the market for investing in Class B US real estate – a segment he says is always in demand
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Papago M8 Singapore/Malaysia v8.2.0 with MFM 111004 Maps
Updated maps details
Install via iTunes or Installous
Download here -
2 parts -
Last edited by Airion; 4th May 2012 at 11:37. Reason: new upload
Thanks. I had already got Papago 8.20 installed.
Can you upload just the map for us to upgrade ?
Can I do that without installthe IPA ? How ?
Sorry I do not quite understand -- need to clarify.
After underloading and unrar the file it is a .ipa file. How do I extract the map from the ipa file ?
Use Winrar to extract the IPA into directory format.
Advice -
Better you delete and reinstalled.
Save the problem of messing up and cannot work.
Installed and working
is it only can be done in the jailbreaked phone?
Last edited by Airion; 15th October 2011 at 01:00.
All IPA here are for jailbroken iphone.
Next time don't code the 1st post


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Elliston, Newfoundland, 2012.
Elliston, Newfoundland, 2012.
Jan 11 011/365 - Buried, St. John's, 2013.
I scanned some wonderful Velvia that I shot a few years ago. It seems like I was on an industrial hype at the time.
Jan 1 001/365 - Fireworks, St. John's, 2013.
My first photo of 2013. I will try to take one every single day this year. Enjoy!
Battery, St. John's, Newfoundland, 2012.
I finally published an online portfolio - check it out at Marc Lafrenière Photography. I'll be adding more photos in the future. You can also view the website in an optimized version on your iPhone 3GS/4, and view the website's original format on the iPad ½.
I want to highlight Krop.com intelligent website design that caters to working artistic professionals in the field of photography, web design, interactive design, creative directors, etc. My favourite feature with them is that you can build a résumé via your profile, it's then linked to your website, and you can also download it in .PDF format for your viewing pleasure.
Jan 7 007/365 - Backyards, St. John's, 2013.
Skerwink Trail, Trinity, Newfoundland, 2012.
Signal Hill, St. John's, Newfoundland, 2012.
Electricity, St. John's, 2012. (first shot with the Nikon D800)
Jan 9 009/365 - Parking Lot, St. John's, 2013.
Some photos taken on the aftermath of Hurricane Leslie in St. John's, Newfoundland & Labrador. All of the photos are within the downtown portion of town.
Jan 2 002/365 - Cards, St. John's, 2013.
I've finally released a fresh new website for my photography. This time around, I went with Squarespace (thank you, Alex). I hope to use them for my website needs for the years to come.
Cabin, Trinity, Newfoundland, 2012.
Rock, Northern Bay Sands, Newfoundland, 2012.
Feather, Northern Bay Sands, Newfoundland, 2012.
Blanket, Conception Bay South, Newfoundland, 2012.
Sky, Conception Bay South, Newfoundland, 2012.
Jan 4 004/365 - Light Post, St. John's, 2013.


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London is the love of my life. Our magnificent capital has been my happy home for 29 years. But every day my heart sinks a little lower, as I watch more flash developments slowly devour the city's vibrancy, diversity and soul. Billboards advertising "luxury flats coming soon" may as well read "your time is up, millennials!" The cost of living here is spiralling out of control, and the burden is becoming too much for the young to bear.
It might seem foolish to talk about a football competition and a democratic election as if they were comparable. Maybe I've extrapolated a certain mawkish sentimentality from the simple facts. Maybe. But if they only other option is certainty of failure, I'll take possibility of the improbable, thanks.
The bookmakers have George Galloway in third place for the position of Mayor of London, which is determined by the Supplementary Vote. Neither Sadiq Khan nor Zac Goldsmith stands any realistic chance of winning outright on first preferences. They, and all other Mayoral candidates who want to win, need to start engaging with Galloway's policy proposals.
FGM is a practice that would seem out of place in the dark ages, and yet it is being inflicted on young people living in our city today. Its frequency is a worrying phenomenon that cannot be ignored. Yet despite its apparent prevalence in the UK, not a single conviction for the illegal practice has ever been achieved.


text:
The Big Hits, The Best Years
The original station transmitted on 855 AM in Shropshire, Worcestershire & Herefordshire and played music from the 60s to the present day, along with features, local news, sport, weather, travel information and more. Sunshine 855 is now known as simply Sunshine Radio and broadcasts live from Ludlow in Shropshire, forming part of a family of stations broadcasting under the same name with FM services in Hereford and Monmouth.
No schedule available for this radio station.
Radioline gives to users access to more than 60.000 News, Sports, Talk, Music radio stations and podcasts worldwide. The user can easily find and listen to his favorite radio stations, and discover new ones according to his mood, location, musical taste and more!


text:
Separate names with a comma.
Discussion in 'Network: North' started by DLAWNS, Nov 8, 2008.
The enclosed is sold. Still have the open and 48 wb
Posted via Mobile Device
Tim - thanks! Know of anyone selling a decent diesel? Nothing fancy, just a work truck.
1996 GMC 3500 HD Turbo Diesel w/9' hydraulic dump, tool box not pictured
100k honest miles, new clutch & tie rods, rebuilt 5 speed manual trans,
Hey still have the 48'' if anyone is interested of knows anyone...
2000obo...gear driven...jungle jims..great shape..15hp kawasaki
mower was a back up..barley used..in great shape...need to sell to get engine for my zt...thanks for looking and shoot me any questions...
a little late, but Reed and Perrine is having their annual seminar, Tuesday Feb. 15, 2011 at the Battleground Country Club in Manalapan. 3b -5 points, 3a - 3 points, core 2 points , ppv 5 point.
Must come into store and sign up by Friday 2/10/11. $30.00 cash or check. with a copy of your pesticide license.
Reed and Perrine is located on Main st in Tennent.
Who is going for their pesticide license soon ?
Is anyone going to the NJLC trade show march 2
Any other info on it?
Yup, I'll be there
Just checked out the website. Not sure but going to try.


text:
I don't look back on this same Trulia thread for answers posted after mine.
562-430-3053 c
Realtor Since 1996
Main Street Realtors
I have heard people actually sending rental deposit to Nigeria and then expecting keys back.. it happened in one of my listings.... common sense is the best answer...take a step back (like you did) and ask if it makes sense...
Best of luck!
I actually called the internet police!!!! Crimes on the internet, they first came from POSTLETs.
The cheap rentals are a sign, and they don't talk to you personally or give you a phone number, RUN!
The scam goes like this, an owner puts their house up for sale through a realtor. The realtor does their job, takes photos and lists it on various websites including Trulia and Craig's list. Foreign con artists see the listing, steal the photos and offer it for rent at an unbelievably good price (which should be your first clue) and say, 'we were going to sell but changed our minds' and 'we were relocated for our job to (fill in the blank, some foreign country), or 'we are missionaries' and then they ask you to email an application and eventually wire transfer the secuirty deposit and first month's rent to a foreign bank. Your money is GONE, the house is NOT for rent and they are NOT the owners! I have even heard horror stories of people showing up with a lease and a moving van.
Please, don't fall for this scheme and, please, let those in authority know if you suspect such a scheme. It needs to end and the only way to make it end is for it to be reported.


text:
Golden Globes 2015 early arrivals: Rosamund Pike, Michelle Monaghan, and more
Next gallery »Golden Globes 2015: See the Cast of Orange Is the New Black
« Previous galleryThe greatest actor-director teams in movie history
Judd Apatow and Leslie Mann
The funniest couple on the carpet? Has to be Apatow and Mann.
Photo Credit:


text:
The Monterey Institute of International Studies is home to a terrorism studies program. Damian Trujillo explains why experts there want to know if the terrorists were home grown, or it they were influenced by international radicals.
Published at 2:46 AM GMT on Apr 20, 2013 | Updated at 3:03 AM GMT on Apr 20, 2013


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Part-Time Team member
Retail Sales-Seasonal Freight Associate (Early Morning)
Retail Sales Associate
Retail Associates (Multiple Positions)
Seasonal Sales Associates
Chief Administrative Officer-LMC
Customer Service Rep(09705) - 602 South Main Street
Seasonal Associate
Student Drivers
Warehouse Clerk - Part Time
Team Member - Crew Member
Crew Member
Seasonal Position - Cashier
Product Tester (From Home)
Entry Level Sales and Sales Management
Regional Truck Driver - Job Opportunity For Veterans
Assembly Technician
UPS Package Handler - Part-Time - Entry Level Warehouse Support
Retail Project Merchandiser Part Time
Retail Sales Consultant - Seasonal
Retail Sales Consultant - Rice Lake
Sales Associate-CEDAR
Guest Service Co-worker Kwik Trip #426- 3rd Shift
Find the career you've been looking for.
The Rice Lake, WI Job Market
Looking for decent jobs in Rice Lake, WI? Rice Lake, WI holds a population of approximately 8,400, as of 2013 government records. The median family take-home pay level of Rice Lake, WI is approximately $35,000, as reported by BLS stats info as of roughly 2013 Rice Lake's cost of living, since 2013, was around 81 out of 100, and that is lower than the nationwide average.
Recently since 2014, Rice Lake has an unemployment rate of somewhere around 5.9%. This is higher than the nationwide average unemployment rate, as of late 2015. This might be valuable pondering if you may be researching careers in the city, living in a different place and looking in nearby cities, or if you are hoping for locations truly worth moving to, that also have excellent job possibilities.


text:
More rain and thunderstorms are expected to hit the Hall County area and could linger throughout the work week.
Clermont's mayor and council members may see their first raise since 1995.
Flowery Branch has completed energy-saving improvements to its sewer treatment plant off Atlanta Highway.
New bikes will soon make their debut at North Georgia College & State University and campus officials hope they will jump-start a sustainability movement.
The Georgia State Patrol is investigating a one-vehicle wreck off Hog Mountain Road in South Hall.
Flowery Branch plans to start informally talking with property owners in the path of potential road projects to see if they would be interested in selling their land, at some point, to the city.
Nancy F. Krippel understands the power hope wields in a college classroom. As dean of adult and graduate studies and associate dean of Mary Baldwin College in Staunton, Va., she has enjoyed sharing her own story in order to lift others.
Built on a hill, downtown Flowery Branch has bore the brunt of unforgiving rainfalls.
It's no coincidence that Paso Fino horses are known for their "fine step" - it's the translation of their name.
Lessie Smithgall keeps an antique clock on the mantle in her living room.
The foot chase had ended, he thought. It was dark, wooded, 2 a.m. and the Atlanta carjacker whom Woodrow Tripp ran after as a city cop appeared hurt and motionless at the bottom of a shallow ravine.
Hall County's city, county and state elected officials have a good record of attending their monthly meetings.
One person was injured Saturday after a driver drove off the road and overturned their vehicle into a mobile home, a Georgia State Patrol communications officer said.
When John Osborne heard Jamie Hood was accused of shooting to death an Athens-Clarke County police officer and wounding another, the news struck a nerve.
Page 1128 of 1898
A referendum that would allow the state to take over failing schools doesn't get much attention in local schools, according to principals and superintendents.
It's hard to imagine living without one of our five senses to navigate the world. But for many, a life without sight or hearing ...
A showdown in the square used to mean something very specific. Typically, it involved gruff leather clad men, drawn guns and squabbles settled by a ...
An upcoming Netflix series will shoot a scene at a Flowery Branch barbecue restaurant in the coming weeks.
Leigh Corley has opened a pediatric therapy clinic in Clermont after nearly 20 years of working with children mostly in their homes.
As the local and regional real estate market continues to steady itself following the economic recession, one glaring problem remains in Hall County: the need ...
When first-grader Malone Bennett heard her friend Brecklynn Allgood was sick, she wanted to help.
Two well-known women with experience and knowledge about the impact women, minorities and young people have on American politics will speak at a program at ...
Lanier Technical College will host Career Fair 2016 from 10 a.m. to 1 p.m. Wednesday.
Clearing will begin soon for the widening of Ga. 13 from Sawnee Avenue in Gwinnett County to Lanier Islands Parkway/Ga. 347 in Hall County.
Selfless, aspiring visionaries: this is how three Hall County men were described as they were recognized Thursday night by the North Georgia Community Foundation.
A 187-lot subdivision planned off busy Spout Springs Road in South Hall can move forward now that rezoning was approved by the Hall County Board ...
Braving winter weather
Page 8 of 8
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A new conversation has begun between doctors and patients: talking about money and health care, and what treatments cost — specifically, what a particular treatment will cost a patient, out-of-pocket.
Over a dozen physician professional societies are proponents of these discussions, and are providing support to doctors in their networks.
Doctors already engaging in the topic of the cost of care with patients aren't being altruistic about spending this precious time in the already-time-constrained patient encounter: these discussions are increasingly relevant to physicians' financial outcomes.
I'll be addressing this new feature in the doctor's office at the upcoming Point-of-Care conference, September 30, 2014, in Baltimore, in my talk – Health Economic Conversations Enter the Physician-Patient Relationship, sponsored by DTC Perspectives.
Heath Populi's Hot Points: Patients and physicians engaging in shared decision-making have the additional issue of the cost of treatment to add into their conversations. The results of these discussions impact both sides of the dialogue, in terms of health outcomes and financial wellness. The more prepared a patient is — clinically and financially — before a treatment is undertaken — the more likely the patient will fare better in health engagement and outcome, and the less likely the patient will experience 'sticker shock' at the point of payment or receipt of the EOB statement. These conversations, which bring financial transparency to health consumers, can help bolster physicians' bill collections – a growing problem as people take on more financial risk in the high-deductible health plan environment.
Leave a Reply
2 Comments on "Health economics in the exam room: doctors and patients discussing the costs of health care"
Hi Jane, have you seen this provocative, ironic, and sarcastic perspective on the recent admonishments from Peter Ubel and the misappropriation of shared decision making as a tool to deny services to the poor? http://feedly.com/e/IxkKw5w1
[…] about "patient affordability" in building the Journey understanding is not trivial. I recently discussed this here in Health Populi, where consumers bundle financial health into overall health and […]


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You are using an unsupported version of . Some features may not work correctly. Please install the latest version of .
learn the differences between the various instruments and the reasons for selecting one collateral approach over another
Banking, Finance, Investing, Accounting
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text: I heard about a story last week in which an Air Canada 767 had to divert to Stephenville, Newfoundland during a CDG-YYZ flight. I checked my Canadian aviation handbook and it shows that Stephenville (YJT) has a 10000 ft x 200 ft runway. Does anyone know why such a major runway was built there (obviously Air Canada is thankful that they did)? I understand the reasons for Gander and St. John's but why Stephenville?


text:
Play Video
Miramax Films: No Country For Old Men - No Informa
Posted by NewMovies on Nov. 09, 2007
The new season of The Walking Dead is just around the corner, and after tha...
Hey Break fans! Check out our latest compilation, Car Crashes & Chaos Part ...
Learn everything you need to know about how to climb Mount Everest!
Posted by NewMovies on Nov. 09, 2007


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November 20, 2009
BayALN is a superb way to keep growing as an agile sponsor, mentor, trainer and coach.
BayALN is essential for staying on top of your Agile game.
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The new user profile I've designed for the new Whyd Paris page.
keyboard shortcuts:
L or F like
Z toggle zoom
post comment
Show and tell for designers
What are you working on? Dribbble is a community of designers sharing screenshots of their work, process, and projects.
Copyright © 2009–2016 Dribbble LLC. All screenshots © their respective owners. Shipped from Salem, Mass. USA.


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All Entries Tagged With: "pixelespresso"
PixelEspresso releases Decloner 1.4 for Mac OS X 10.6 Snow Leopard
Posted by Press Releases | Apr 29, 2011 | 0
UK based PixelEspresso today announces Decloner 1.4, an update to their easy-to-use utility to find and eliminate duplicate files on Macintosh computers running Mac OS X 10.6 Snow Leopard or newer. Decloner uses the extremely reliable SHA-1 algorithm to determine if files are identical. It presents the duplicates found in a list that allows manual or automatic selection of files to remove. It can quickly process large number of files on internal, external or network drives, and much more.


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November 16, 2010
My company is currently working Biofuel and I am the automation specialist to facilitate the process.
Ben Hsieh here. Lab automation specialist in the biotech field. Active inventor and CAD drafter
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text:
Classic Shellfish Stew
|Extra virgin olive oil
|1 Teaspoon
|Finely chopped onions
|1⁄2 Cup (8 tbs)
|1 Clove (5 gm), minced
|Diced plum tomatoes
|1 Cup (16 tbs), drained (fresh or canned)
|Dry white wine/Clam juice
|1 Cup (16 tbs)
|Chopped fresh italian parsley
|1⁄4 Cup (4 tbs)
|Hot pepper sauce
|1 Dash
|To Taste
|Black pepper
|To Taste
|Littleneck clams
|1 Pound, scrubbed
|1 Pound, scrubbed and debearded
|Medium shrimp
|8 Ounce, peeled and deveined
Coat a large saucepan with no-stick spray; add the oil over medium-high heat.
Add the onions and saute for 1 minute.
Add the garlic and continue cooking for 3 minutes, or until the onions and garlic become very soft.
Add the tomatoes, wine or clam juice, pars ley and hot-pepper sauce; add salt and black pepper to taste.
Lower the heat, cover and simmer for about 20 minutes.
Uncover and continue cooking for 5 minutes, or until the liquid is slightly reduced.Add the clams and mussels.
Cover and cook for 3 minutes.
Check to see if they are beginning to open.
If not, cover and cook another minute.
If so, add the shrimp and continue cooking, uncovered, for another 2 to 3 minutes, or until the shellfish have opened and the shrimp are pink.
Discard any mussels or clams that have not opened.
Recipe Summary
Rate It
Nutrition Rank
Nutrition Facts
Serving size: Complete recipe
Calories 1262 Calories from Fat 215
% Daily Value*
Total Fat 24 g36.5%
Saturated Fat 3.1 g15.4%
Trans Fat 0 g
Cholesterol 631.7 mg210.6%
Sodium 2313.8 mg96.4%
Total Carbohydrates 53 g17.5%
Dietary Fiber 3.3 g13.4%
Sugars 5.1 g
Protein 159 g317.5%
Vitamin A 54.2% Vitamin C 119.1%
Calcium 29.6% Iron 143.6%
*Based on a 2000 Calorie diet


text:
- Aa
- Aa
Codron, P. and Verny, C. 2016. Encefalopatie metaboliche e tossiche non farmacologiche. EMC - Neurologia, Vol. 16, Issue. 3, p. 1.
Dias, Maria Inês Morales, Patricia Barreira, João C.M. Oliveira, M. Beatriz P.P. Sánchez-Mata, Mª Cortes and Ferreira, Isabel C.F.R. 2016. Minerals and vitamin B9 in dried plants vs. infusions: Assessing absorption dynamics of minerals by membrane dialysis tandem in vitro digestion. Food Bioscience, Vol. 13, p. 9.
Karamshetty, Varun Acharya, Jhankar D. Ghaskadbi, Saroj and Goel, Pranay 2016. Mathematical Modeling of Glutathione Status in Type 2 Diabetics with Vitamin B12 Deficiency. Frontiers in Cell and Developmental Biology, Vol. 4,
Pacheco Da Silva, Fabiana Fernanda Biscola, Vanessa LeBlanc, Jean Guy and Gombossy de Melo Franco, Bernadette Dora 2016. Effect of indigenous lactic acid bacteria isolated from goat milk and cheeses on folate and riboflavin content of fermented goat milk. LWT - Food Science and Technology, Vol. 71, p. 155.
Ferrari, Ariana de Carvalho, Aline Steluti, Josiane Teixeira, Juliana Marchioni, Dirce and Aguiar, Samuel 2015. Folate and Nutrients Involved in the 1-Carbon Cycle in the Pretreatment of Patients for Colorectal Cancer. Nutrients, Vol. 7, Issue. 6, p. 4318.
LeBlanc, Jean Guy Laiño, Jonathan Emiliano del Valle, Marianela Juárez de Giori, Graciela Savoy Sesma, Fernando and Taranto, María Pía 2015. Biotechnology of Lactic Acid Bacteria.
Meissen, John K. Hirahatake, Kristin M. Adams, Sean H. and Fiehn, Oliver 2015. Temporal metabolomic responses of cultured HepG2 liver cells to high fructose and high glucose exposures. Metabolomics, Vol. 11, Issue. 3, p. 707.
Morales, P. Fernández-Ruiz, V. Sánchez-Mata, M. C. Cámara, M. and Tardío, J. 2015. Optimization and Application of FL-HPLC for Folates Analysis in 20 Species of Mediterranean Wild Vegetables. Food Analytical Methods, Vol. 8, Issue. 2, p. 302.
Murto, Tiina Kallak, Theodora K. Hoas, Annica Altmäe, Signe Salumets, Andres Nilsson, Torbjörn K. Skoog Svanberg, Agneta Wånggren, Kjell Yngve, Agneta and Stavreus-Evers, Anneli 2015. Folic acid supplementation and methylenetetrahydrofolate reductase (MTHFR) gene variations in relation to in vitro fertilization pregnancy outcome. Acta Obstetricia et Gynecologica Scandinavica, Vol. 94, Issue. 1, p. 65.
Shemanaeva, T. V. and Voevodin, S. M. 2015. Role of folic acid in the prevention of fetal nervous system diseases. Rossiiskii vestnik akushera-ginekologa, Vol. 15, Issue. 5, p. 25.
Spann, Marisa N. Smerling, Jennifer Gustafsson, Hanna Foss, Sophie Altemus, Margaret and Monk, Catherine 2015. Deficient maternal zinc intake—but not folate—is associated with lower fetal heart rate variability. Early Human Development, Vol. 91, Issue. 3, p. 169.
2015. How Enzymes Work.
Barua, Subit Kuizon, Salomon and Junaid, Mohammed A 2014. Folic acid supplementation in pregnancy and implications in health and disease. Journal of Biomedical Science, Vol. 21, Issue. 1,
Duplessis, M. Girard, C.L. Santschi, D.E. Lefebvre, D.M. and Pellerin, D. 2014. Milk production and composition, and body measurements of dairy cows receiving intramuscular injections of folic acid and vitamin B-12 in commercial dairy herds. Livestock Science, Vol. 167, p. 186.
Duplessis, M. Girard, C.L. Santschi, D.E. Laforest, J.-P. Durocher, J. and Pellerin, D. 2014. Effects of folic acid and vitamin B12 supplementation on culling rate, diseases, and reproduction in commercial dairy herds. Journal of Dairy Science, Vol. 97, Issue. 4, p. 2346.
Glier, Melissa B. Green, Timothy J. and Devlin, Angela M. 2014. Methyl nutrients, DNA methylation, and cardiovascular disease. Molecular Nutrition & Food Research, Vol. 58, Issue. 1, p. 172.
Jing, M. Munyaka, P. M. Tactacan, G. B. Rodriguez-Lecompte, J. C. O, K. and House, J. D. 2014. Performance, serum biochemical responses, and gene expression of intestinal folate transporters of young and older laying hens in response to dietary folic acid supplementation and challenge with Escherichia coli lipopolysaccharide. Poultry Science, Vol. 93, Issue. 1, p. 122.
Laiño, Jonathan Emiliano Juarez del Valle, Marianela Savoy de Giori, Graciela and LeBlanc, Jean Guy Joseph 2014. Applicability of a Lactobacillus amylovorus strain as co-culture for natural folate bio-enrichment of fermented milk. International Journal of Food Microbiology, Vol. 191, p. 10.
Rush, E C Katre, P and Yajnik, C S 2014. Vitamin B12: one carbon metabolism, fetal growth and programming for chronic disease. European Journal of Clinical Nutrition, Vol. 68, Issue. 1, p. 2.
Baltar, Valéria Troncoso Xun, Wei W. Johansson, Mattias Ferrari, Pietro Chuang, Shu-Chun Relton, Caroline Ueland, Per Magne Midttun, Øivind Slimani, Nadia Jenab, Mazda Clavel-Chapelon, Françoise Boutron-Ruault, Marie-Christine Fagherazzi, Guy Kaaks, Rudolf Rohrmann, Sabine Boeing, Heiner Weikert, Cornelia Bueno-de-Mesquita, Bas Boshuizen, Hendriek van Gils, Carla H. Onland-Moret, N. Charlotte Agudo, Antonio Barricarte, Aurelio Navarro, Carmen Rodríguez, Laudina Castaño, José Maria Huerta Larrañaga, Nerea Khaw, Kay-Tee Wareham, Nick Allen, Naomi E. Crowe, Francesca Gallo, Valentina Norat, Teresa Krogh, Vittorio Masala, Giovanna Panico, Salvatore Sacerdote, Carlotta Tumino, Rosario Trichopoulou, Antonia Lagiou, Pagona Trichopoulos, Dimitrios Rasmuson, Torgny Hallmans, Göran Roswall, Nina Tjønneland, Anne Riboli, Elio Brennan, Paul and Vineis, Paolo 2013. A structural equation modelling approach to explore the role of B vitamins and immune markers in lung cancer risk. European Journal of Epidemiology, Vol. 28, Issue. 8, p. 677.
The folates are made up of a pterdine ring attached to a p-aminobenzoate and a polyglutamyl chain. The active form is tetrahydrofolate which can have C1 units enzymically attached. These C1 units (as a formyl group) are passed on to enzymes in the purine pathway that insert the C−2 and C−8 into the purine ring. A methylene group (−CH2−) attached to tetrahydrofolate is used to convert the uracil-type pyrimidine base found in RNA into the thymine base found in DNA. A further folate cofactor, i.e. 5-methyltetrahydrofolate, is involved in the remethylation of the homocysteine produced in the methylation cycle back to methionine. After activation to S-adenosylmethionine this acts as a methyl donor for the dozens of different methyltransferases present in all cells. Folate deficiency results in reduction of purine and pyrimidine biosynthesis and consequently DNA biosynthesis and cell division. This process is most easily seen in a reduction of erythrocytes causing anaemia. Reduction in the methylation cycle has multiple effects less easy to identify. One such effect is certainly on the nerve cells, because interruption of the methylation cycle causing neuropathy can also happen in vitamin B12 deficiency due to reduced activity of the vitamin B12-dependent enzyme methionine synthase (EC 126.96.36.199). In vitamin B12 deficiency, blocking of the methylation cycle causes the folate cofactors in the cell to become trapped as 5-methyltetrahydrofolate. This process in turn produces a pseudo folate deficiency in such cells, preventing cell division and giving rise to an anaemia identical to that seen in folate deficiency.
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amputee,crutches Flickr Hive Mind ... 50 amputee crutches 32 woman 31 stocking nylon stump 30 sak 14 women onelegged 3 legamputee handicapped disabledwoman ... - read more
Jun 02, 2014 · Female amputees shane huffman; 107 videos; ... I Am Here to Stay Spina Bifida Special Needs ... I choose to live.mp4 by moi621. 14:33. Play next; Play now; - read more
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