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Interleukin-18 Is a Strong Predictor of Cardiovascular Death in Stable and Unstable Angina
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Background— Interleukin (IL)-18 plays a central role in orchestrating the cytokine cascade and accelerates atherosclerosis and plaque vulnerability in animal models. However, epidemiological data evaluating the role of IL-18 levels in atherosclerosis are lacking.
Methods and Results— In a prospective study of 1229 patients with documented coronary artery disease, we measured baseline serum concentrations of IL-18 and other markers of inflammation. During the follow-up period (median, 3.9 years), 95 patients died of cardiovascular causes. Median serum concentrations of IL-18 were significantly higher among patients who had a fatal cardiovascular event than among those who did not (68.4 versus 58.7 pg/mL; P<0.0001). The hazard risk ratio of future cardiovascular death increased with increasing quartiles of IL-18 (hazard risk ratio, 1.46; 95% CI 1.21 to 1.76; P for trend <0.0001). After adjustment for most potential confounders, including the strong predictor ejection fraction as well as the inflammatory variables IL-6, high-sensitive C-reactive protein, and fibrinogen, this relation remained almost unchanged, such that patients within the highest quartile of IL-18 had a 3.3-fold increase in hazard risk compared with those in the first quartile (95% CI, 1.3 to 8.4, P=0.01). This relation was observed in patients with stable angina and patients with unstable angina at baseline.
Conclusions— Serum IL-18 level was identified as a strong independent predictor of death from cardiovascular causes in patients with coronary artery disease regardless of the clinical status at admission. This result strongly supports recent experimental evidence of IL-18–mediated inflammation leading to acceleration and vulnerability of atherosclerotic plaques.
Received April 10, 2002; revision received April 23, 2002; accepted April 23, 2002.
Inflammatory mediators are intimately associated with the cascade of events leading to atherosclerotic plaque initiation, development, and rupture.1,2⇓ This recognition has stimulated the evaluation of several markers of inflammation as potential tools for cardiovascular risk prediction.3,4⇓
Interleukin (IL)-18, originally identified as an interferon (IFN)-γ–inducing factor in Kupffer cells and macrophages, 5 plays a central role in the inflammatory cascade and in the processes of innate and acquired immunities because of its ability to induce IFN-γ production in T lymphocytes and natural killer cells, which is believed to play a crucial role in atherosclerotic plaque rupture.6,7⇓ Furthermore, IL-18 acts in synergy with IL-12 to promote the development of T helper 1 (TH1) responses.8–10⇓⇓
Recently, increased IL-18 expression has been reported in human atherosclerotic plaque,11 mediating INF-γ release locally.12 Furthermore, animal models support the proatherogenic role of IL-1813 as well as the beneficial effect of inhibiting IL-18 on plaque progression and composition.14 Although one study demonstrated elevated levels of IL-18 in patients with acute myocardial infarction,15 no data exist on the prognostic impact of IL-18 on future cardiovascular events.
On the basis of the above-mentioned experimental data, we evaluated whether baseline serum levels of IL-18 might be predictive of future fatal cardiovascular events in patients with coronary artery disease (CAD). We especially aimed to investigate the predictive power of IL-18 in comparison with other markers of chronic inflammation.
Study Population
Between November 1996 and June 2000, 1299 patients who underwent coronary angiography at the II Medical Department of the Johannes Gutenberg-University Mainz or the Bundeswehrzentralkrankenhaus Koblenz, with at least 1 stenosis >30% diagnosed in a major coronary artery were enrolled in a cardiovascular registry (AtheroGene Study). For the present study, we excluded 70 patients with acute myocardial infarction within the preceding 48 hours; therefore the final study cohort consisted of 1229 patients, who provided plasma and serum samples that were stored at −80°C until analysis. A detailed study description has been outlined elsewhere.16 Briefly, exclusion criteria of the AtheroGene study were evidence of hemodynamically significant valvular heart disease, surgery or trauma within the prior month, known cardiomyopathy, known malignant diseases, febrile conditions, or oral anticoagulant therapy within the prior 4 weeks. Unstable angina (n=374) was classified by Braunwald classification (class B or C).
Patients were followed up during a median of 3.9 (maximum: 5.2) years. Follow-up information was obtained about death from cardiovascular causes (n=95), death from causes not related to heart disease (n=18), and nonfatal myocardial infarction (n=43). Information about the cause of death or clinical events was obtained from hospital or general practitioner charts.
Study participants had German nationality. The ethics committee of the University of Mainz approved the study. Participation was voluntary, and each study subject gave written informed consent.
Laboratory Methods
Serum IL-18 was measured with a commercially available ELISA method (MBL Co, Ltd). Coefficients of variation ranged from 3% to 14%, and repeat determinations on the same serum sample were highly correlated (r=0.98). C-reactive protein was determined by a highly sensitive, latex particle–enhanced immunoassay (detection range of 0 to 20 mg/L, Roche Diagnostics), IL-6 by ELISA (EASIA, Biosource Europe), fibrinogen by a derived method, and troponin I by an immunoassay (DADE Behring). Lipid serum levels were measured immediately.
Statistical Considerations
Mean levels of variables were compared across quartiles of IL-18 by ANOVA for normal variables, Kruskall-Wallis test for skewed variables, and χ2 test for categorical variables. In all survival analyses, the end point was death from cardiovascular causes, and data on patients who died of other causes were censored at the time of death. The association of IL-18 with outcome was evaluated by Cox regression analysis adjusted for potential confounders. In these analyses, IL-18 and other inflammatory markers were considered either as continuous variables (log-transformed) or in quartiles. Hazard risk ratios (HRRs) and 95% CIs are reported with 2-tailed probability values. A value of P<0.05 was considered to be significant. All computations were carried out with SPSS, version 10.07.
Characteristics of the Study Population
Table 1 gives patient characteristics according to quartiles of IL-18. The median IL-18 level was 59.6 pg/mL (25th/75th interquartile, 45.0/77.7). When stratifying data for patients with stable or unstable angina, similar results were observed in the two groups except for the association with high-sensitive C-reactive protein (hs-CRP) and IL-6, which was mainly driven by patients with unstable angina.
IL-18, Markers of Inflammation and Necrosis, and Cardiovascular Risk Factors
Unlike the other inflammatory markers (IL-6, hs-CRP, and fibrinogen), IL-18 levels did not correlate with age (Table 2). By contrast, the negative correlation of HDL cholesterol and IL-18 was of a magnitude similar to that observed with other inflammatory markers. IL-18 concentrations showed a modest correlation with hs-CRP and IL-6, mainly in patients with unstable angina, but did not correlate with fibrinogen levels. This result strikingly contrasted with the strong associations observed within the cluster of the 3 acute phase reactants. In unstable angina, levels of the myocardial necrosis marker troponin I correlated with hs-CRP, IL-6, or fibrinogen but not with IL-18 (Table 2).
IL-18 Concentrations and Future Death From Cardiovascular Causes
As shown in Figure 1, median serum concentrations of IL-18 at baseline were significantly higher among patients who had a fatal cardiovascular event during follow-up than among those who did not (68.4 versus 58.7 pg/mL, P<0.0001). The upper two quartiles of IL-18 had the highest probability of death from cardiovascular causes during the entire follow-up period (Figure 2). As further demonstrated in Table 3, each quartile increase in baseline IL-18 concentration was associated with a 1.46 (95% CI, 1.21 to 1.76; P<0.0001) increase in risk for future cardiovascular death. The association of IL-18 and future fatal events was present in all patients regardless of target vessel revascularization. However, the strongest relation between IL-18 levels and future events was seen in those individuals who were not treated by invasive strategy. Furthermore, the relation between IL-18 concentration and future cardiovascular events was mainly present in patients without statin intake at baseline, although the interaction term did not reach significance (P=0.4). However, these results must be interpreted with caution because there were only a small number of cardiovascular deaths in patients receiving statin therapy at baseline (n=24).
To assess whether the effect of baseline IL-18 on risk was independent of hs-CRP, IL-6, and fibrinogen, a Cox regression model was applied including all four markers simultaneously (Table 3, Model 2). Adjustment for these inflammatory markers had no impact on the association between IL-18 and future cardiovascular events. If hs-CRP was introduced in the multivariate model comparing the inflammatory variables as a categorical variable by use of the threshold of upper versus lower quartiles (1.3 mg/dL), patients within the highest hs-CRP quartile revealed a 1.5 (95% CI, 0.9 to 2.5; P=0.1) increase in risk. The association of IL-18 with future fatal events remained highly significant regardless of the way hs-CRP was introduced into the model.
Figure 3 shows the HRRs for cardiovascular death according to quartiles of IL-18 from different Cox regression models. The clear increase of HRRs with increasing levels of IL-18 was observed whatever the model considered. From the final model, which included most potential confounders such as the strong predictor ejection fraction as well as the inflammatory variables, it was estimated that patients within the highest quartile of IL-18 had a 3.3-fold (95% CI, 1.3 to 8.4; P=0.01) increase in hazard risk compared with patients within the lowest quartile.
Outcome in Patients With Stable or Unstable Angina
We further explored the predictive value of IL-18 on cardiovascular death separately in patients with stable angina and patients with unstable angina at admission (Table 4). In both groups, there was a clear increase of risk according to IL-18. It appeared that the threshold above which there was a net excess of risk was shifted toward higher values in the group of patients with unstable angina. However, caution is needed with regard to this observation because the quartile analyses in unstable angina are based on a small sample size compared with the overall study population.
In this prospective and contemporary cohort of patients with documented CAD, we demonstrated for the first time that baseline measurement of IL-18 provides powerful information for future fatal cardiovascular events across the entire spectrum of patients with stable CAD and patients with unstable CAD. The relation between IL-18 and future cardiovascular events was independent of other risk factors and clinical features such as ejection fraction and remained unaffected by various markers of inflammation such as hs-CRP, fibrinogen, or IL-6.
Along with increasing experimental evidence implicating inflammatory and immune reactions in atherothrombosis,1,4⇓ a wide range of circulating markers of inflammation predict cardiovascular risk in a variety of clinical settings.3,4⇓ Consistent findings support a predictive role of CRP in initially healthy individuals17,18⇓ as well as in patients with stable angina and patients with unstable angina.19–21⇓⇓ Furthermore, other inflammatory markers predict future cardiovascular events. Determination of IL-6—the most potent inducer of CRP—provides independent information on future fatal and nonfatal events in different populations,22–24⇓⇓ as does measurement of soluble adhesion molecules.25–27⇓⇓
IL-18 acts as an important regulator of both innate and acquired immune responses.8–10⇓⇓ There are now strong experimental data supporting the hypothesis that a novel pathway for signaling in atherogenesis and plaque vulnerability involves the IL-18 receptor/ligand dyad. IL-18 has been first identified in human atherosclerotic lesions with significantly higher levels of IL-18 mRNA in unstable plaques.11 Furthermore, in vitro stimulation of the IL-18 receptors on endothelial cells or smooth muscle cells triggers atheroma-associated processes such as stimulation of the cytokines IL-6 and IL-8 and expression of adhesion molecules and matrix metalloproteinases.12 Administration of IL-18 was reported to lead to an increase in lesion size and to promote an elevation in the number of lesion-associated T-lymphocytes in animal models. Both effects were abolished in IFN-γ–deficient mice, strongly suggesting the importance of the IFN-γ–dependent pathway.13 Moreover, inhibition of IL-18 signaling by IL-18 binding protein has been shown to reduce lesion progression and to change plaque composition toward a stable feature, with a decrease of inflammatory cells and lipid content and an increase of smooth muscle cells and collagen.14
Taking into account the experimental background together with the present results showing the prognostic value of serum IL-18, this cytokine appears to be an excellent candidate linking local vessel wall pathology with systemic inflammation. The association between serum IL-18 and future cardiovascular events seemed somewhat different from that observed with other acute phase reactants such as hs-CRP, IL-6, or fibrinogen. First, whereas there were moderate to strong interdependencies between hs-CRP, IL-6, and fibrinogen in both stable and unstable angina, IL-18 exhibited a weak correlation with the above-mentioned inflammatory markers. Consequently, when including the inflammatory predictors simultaneously into one model, the predictive value of all acute phase reactants was weakened, whereas the relation between IL-18 and prognosis remained almost unchanged. Second, the predictive power of the inflammatory markers hs-CRP, fibrinogen, and to a lesser extent, IL-6, decreased when adjusted for ejection fraction, whereas the role of IL-18 remained nearly unaffected. It cannot be excluded that the levels of inflammatory markers might serve—at least in part—as surrogates of impaired ejection fraction. However, the ability of IL-18 to induce proatherogenic features12 might have implications on both plaque instability and myocardial dysfunction. In the subgroup of patients with unstable angina, levels of hs-CRP, IL-6, and fibrinogen correlated with troponin I values. This indicates that in the presence of an acute coronary syndrome, elevation of hs-CRP levels might also derive from myocardial (micro)-necrosis. By contrast, levels of serum IL-18 did not correlate with troponin I values, suggesting that elevation of this marker is not a consequence of perfusion or reperfusion injury.
Interleukin-18 gene expression is stimulated by proinflammatory cytokines as well as by lipopolysaccharides. Therefore, infections might be discussed as distant triggers of IL-18, which could provide a potential link between the controversial association of previous infections and future cardiovascular events in patients with CAD.16,28,29⇓⇓
Several limitations of our study deserve consideration. First, measurement of IL-18 was performed at one time only. However, previous studies have shown a continuous release of inflammatory markers during an acute coronary syndrome. Therefore, examining the time course of IL-18 during the cardiovascular event might improve its predictive value. Second, measurement of IL-18 was performed on samples that were stored at −80°C. We cannot exclude the possibility of protein degradation. Assessment of IL-18 is presently an expensive and time-consuming procedure, and before entering in clinical settings, standardized and reproducible assays as well as a consistent series of prospective studies—especially in initially healthy populations—should be available.
In conclusion, in this prospective evaluation of several inflammatory variables, we could demonstrate for the first time the strong and independent association between serum levels of IL-18 and future cardiovascular events in patients with a broad spectrum of CAD. This finding strongly supports the possibility, already suggested by experimental work, that inhibiting IL-18 might constitute a new therapeutic strategy for plaque stabilization.
The AtheroGene Group: Hans-Jürgen Rupprecht, Stefan Blankenberg, Christoph Bickel, Christine Espinola-Klein, Jürgen Meyer; Department of Medicine II, Johannes-Gutenberg University Mainz; Laurence Tiret, Odette Poirier, Viviane Nicaud, Jean-Louis Georges, François Cambien; INSERM U525, Paris.
AtheroGene Recruitment Centers: Department of Medicine II, Johannes-Gutenberg University Mainz; Innere Abteilung, Bundeswehrzentralkrankenhaus, Koblenz.
This study was supported by "Stiftung Rheinland-Pfalz für Innovation," Ministry for Science and Education (AZ 15202-386261/545), Mainz, Germany; Stefan Blankenberg was supported by a grant from the Institut National de la Santé et de la Recherche Médicale (INSERM), Paris, France. We are indebted to Susanne Prigge, Ruediger Walscheid, and Axel Thuy (Labor Koblenz) for determining the IL-18 ELISA and to Margot Neuser for graphic work.
↵*The AtheroGene investigators and recruitment centers are listed in the Appendix.
This article originally appeared Online on June 3, 2002 (Circulation. 2002;105:r143–r149).
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- Interleukin-18 Is a Strong Predictor of Cardiovascular Death in Stable and Unstable AnginaStefan Blankenberg, Laurence Tiret, Christoph Bickel, Dirk Peetz, François Cambien, Jürgen Meyer and Hans J. RupprechtCirculation. 2002;106:24-30, originally published June 3, 2002http://dx.doi.org/10.1161/01.CIR.0000020546.30940.92
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- Interleukin-18 Is a Strong Predictor of Cardiovascular Death in Stable and Unstable AnginaStefan Blankenberg, Laurence Tiret, Christoph Bickel, Dirk Peetz, François Cambien, Jürgen Meyer and Hans J. RupprechtCirculation. 2002;106:24-30, originally published June 3, 2002http://dx.doi.org/10.1161/01.CIR.0000020546.30940.92
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A very warm welcome and hospitable stay. Old hotel, but had all we need for what we paid.
This hotel is a great value for its price..easy walk to the large mall. Great view of makiti at night and good wifi in the rooms!
Stayed at the Golden Peak before and had a nice stay. This year our room was bigger. However, the internet wifi was very poor. The water in the shower was just barely warm. The free breakfast was cold. Not as good as my first visit. Will probably visit again if the price is right.
Its a great stay,a short walk to Ayala Center Mall. Very accessible to transportation. Good buffet breakfast meal.
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subset: commoncrawl


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...Instead of giving my students the answers, I ask enough questions to help them understand why and where they are having trouble. My responsibility, as a tutor, is to help them if they get stuck, try to troubleshoot where they might be going wrong, help them find an example in their textbook or n...
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I started tutoring (German and math) while still in college. My degrees are in Math and German with enough credit hours for minors in Business and History. I have taught classes on German, math and religion.
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text:
No matter what happens throughout the season in terms of peaks (5-2 after beating West Virginia) and valleys (lost last five games) - the 2011 Syracuse football team will be judged as a 5-7 ball club.
Without a bowl to play in now that the season is through, coach Doug Marrone and the staff have to turn the page and look forward to what figures to be a long offseason.
After the 33-20 loss to Pittsburgh on Saturday, Marrone fielded questions on the future of the program, recruiting and what needs to change in order to get the Orange back to a bowl game.


text:
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Huntington Beach Freestyle Volleyball
Six-Hour Volleyball Camp on August 27-29
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The road to victory can be full of bumps -- especially when it comes to volleyball. Help your young athlete master every bump, spike, and pass with today's deal: Pay $60 for a three-day volleyball camp for both girls and boys ages 5 to 18 from Hunting Beach Freestyle Volleyball (a $120 value). Held on August, 27, 28, and 29 from 6:30 to 8:30 p.m. at the indoor Huntington Beach-area facility, this hands-on training camp introduces players to the basics of free style/fast tempo volleyball that's popular around the world. An innovative mix of team play and fast-paced action, the freestyle technique is used at the highest levels of professional volleyball. Led by pro player Tyler Hildebrand, who was once named Volleyball Magazine's player of the year and with members 2012 men's national volleyball team as guests, this clinic helps kids master the strategy and techniques needed to win -- with these new skills, the road to victory has never been smoother.
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Kendrick Brion Painting Co
14320 Abington Heights Dr., Orlando, FL 32828
(407) 380-7016
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STAMFORD - Stamford police are investigating an armed robbery that occurred just before 1 p.m. yesterday.
Police say the suspect went into the Post Grocers on Long Ridge Road, and approached the teller with a gun, demanding cash. The clerk refused to give him any money and the suspect ran off.
No one was hurt.


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Cowboy Western
Home >> new mexico >> mountainair >> justice of the peace >> cowboy wedding
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New Mexico and the entire West, has a deep heritage of tough uniqueness and also individual honor; together with a functional approach of "denims and also diamonds". We create events that commemorate these qualities. Whether it is on horseback or from a mountain top, these solutions can be developed so to put your words of love and also commitment on the wings of eagles as well as murmured right into the ears of angels.
No matter if your wedding is on the plains, in the mountains, on the ranch or in the city at the fanciest of places, we can create a wedding ceremony that embraces your passion for each other and also your country life.
The Ideal Wedding Officiant is important for your Cowboy Wedding Ceremony in Mountainair, New Mexico.
Life's Moments are those times in life that we decide to make a special acknowledgment of life altering occasions. Cowboy Weddings are celebrations, weddings are events, yet most of all weddings are a new beginning, a minute in time to be cherished. Having the right Wedding Minister is important.
For these moments, we provide thorough Justice Of The Peace services, Horseback Cowboy Wedding Ceremony officiating, as well as wedding celebration solutions. From the very standard to contemporary solutions, our weddings and also officiating solutions are developed to reflect your desires, wishes and also desires. We will help you to craft an event, spiritual or nonreligious that will be a valued memory for many years to come.
Ministerial services and wedding celebration officiating in the Mountainair, New Mexico area is our specialty, however we could travel if the need occurs. We give a complete selection of Horseback Cowboy Wedding Ceremony plans; from elopement on the courthouse steps to the most fancy formal wedding you might want.
We also provide the finest in Justice of the Peace or secular weddings. These civil ceremonies provide their very own form of celebration, whether it be with family members or simply a couple and also a couple of witnesses, your cowboy wedding is an unique minute to be valued.
Travel Costs
We Love to Travel! (however our accountant says we have to cover little things like gas, tires and maintenance), so to keep them from chewing our ears off our travel rates are as follows;
Albuquerque/Rio Rancho Metro Area (includes Corrales, Bernalillo, Isleta, Tijeras)
No Charge.
Fee per trip mileage is one way
30 – 60 miles
60—100 miles
101-175 Miles
Over 175 miles
Please call for details
Call 505-328-7397
Rev. Bruce Byers


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text:
Welcome to Librarium Online!
Join our community of 80,000+ members and take part in the number one resource for Warhammer and Warhammer 40K discussion!
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can't add much to that, what can really hurt the VC? just generaly what are some weak points in the army. anything that could be capatalized on by an empire player would be even more so appreciated. thanks in advance to anyone helping out the bewildered new guy.
that's the thing about perfection, it can only get worse.
Main weaknesses vs Empire:
Shooting - empire has very good shooty units, from handgunners, to hellblaster volley guns. Nothing much you can do about this but present your invokeable units to be shot at.
Detachments - unique empire ability for infantry. Very hands and allows them to put a unit attached to a parent unit that declared a charge reaction at the same time as the parent unit (eg. you charge a parent unit of spears with your skellies who declare hold, the detachment handgunners declare stand and shoot). Also, this is handy for negating rank with flank charges, so guard your flanks!
Numbers - can be quite numerous, so don't automatically expect to outnumber him with your ability to invoke. Invoke to flanks / rears when close combat is near and combine your charges.
That's all I can think of for now.
The iron crowned is getting closer,
Swings his hammer down on him,
Like a thunderstorm he's crushing,
Down the Noldor's proudest king.
Under my foot, so hopeless it seems.
You've troubled my day, now feel the pain.
- Blind Guardian
Their priests are pretty nasty against the undead and there knights with a grand master in the front( garnd master makes all the knights in his unit Immune against PSY)
also magic heavy armys as they have enougth dice effect all you spells
Yes people i know that my spelling and punctuation is awful but I am product of British teaching pollicies so what can I do about it?
make sure to make your units imune to fear whenever possible. then use big blocks of units so you can outnumber them 25+
have detachments that can charge the flanks.
use pistolers to shoot down any character that is running around by himself
mortars are very usefull on big blocks of zombies/skeletons
and handgunners are very suited for shooting down graveguards.
use cannons for blackknihgts...
at last make sure to be able to counter his magic
oops, i'm the empire player, i'll be facing vamps, sorry for not being clear. shooting sounds good, though anyone have tips on how to keep gunlines intact? with fell bats, wolves, and summoned units i'm a bit worried about how few turns my lines will have to fire. and the grandmaster makes one unit of knights great, and is the better stats line, but that leaves everyone else on their own with their basic humie LD. is that one knight unit really worth it, can they do that much damage?
that's the thing about perfection, it can only get worse.


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Ed Sheeran Gets Giant Lion Tattoo On Chest: "Ouch" — SEE PHOTO!
Ed Sheeran is in the process of getting a giant lion tattoo on his chest. See photo below.
The singer revealed the unfinished artwork on Instagram on Tuesday. As it stands right now, the center of Sheeran's chest, between his two nipples and extended from under his neck down to his rib cage, features a big, lifelike portrait of a lion's face. It's unclear what Sheeran plans to add to it.
He captioned the Instagram photo, "Halfway and ouch." A number of fans were impressed, such as the person who flirtingly wrote, "Yes honey you are my kinda guy." Another simply exclaimed, "Wow," while someone else declared, "Looks freaking amazing."
Sheeran's tattoo actually bears resemblance to Cecil, the beloved lion who was murdered by an American dentist in Zimbabwe last month, sparking outrage among celebrities. There's no indication, though, that the British star was intending to pay tribute. And Sheeran, of course, has many other tattoos.
Sheeran's left arm is nearly a full sleeve, while his right has some open space, but that may not last for long. Perhaps among the most noteworthy ink are those that tribute to friends, including the "RED" logo, in honor of Taylor Swift's album. Check out Sheeran's new lion tattoo below, and tell us what you think.


text:
فيديواكس سكس بنات سكس ساريه السواس that should not make him stop begging. Being one of the most contrasting countries in Southeast Asia, how does Malaysia turn several influencies into indigenous habits, how does it link back to its cultural roots? It`s been a while since we`ve seen you on PSP, Naruto -- and it looks like you`ve grown up. It provides a cold but great feeling. سكس بنت When the gasoline ignites, it pushes on the piston, and the piston exerts pressure on the crankshaft, causing it to turn. سكس هيفاء وهبي Gently breathe out of your mouth on the cheek/neck, and listen to them giggle and groan with delight! Asian music encompasses numerous different musical styles originating from a large number of Asian cultures. سكس ساريه السواس Naruto continues to be great mainstream entertainment. سكس هيفاء وهبي These tend to be the shows that are original stories, but the vast majority are pitched by the sponsors, which could be the manga publisher, who`s out to use the anime to promote merchandise or the original manga, or a media company like Media Factory or Geneon Japan or Bandai Visual, who are interested in using the TV broadcast to promote the eventual DVD release. If you`re curious about the genre, a long-time fan or are also simply curious about what Go! Comi is also capable of, Tenshi Ja Nai! will also serve you well. فيديواكس سكس بنات As with boot-cut hems, the trend began in Europe and spread rapidly around the world. سكس بنت That means that the piston is also traveling a relatively long distance up and down in its cylinder on each cycle.
سكس بنت Several forms of musical experience get mingled as it is the Gamelan ensemble combined with traditional instruments of the Arabian peninsula or the call of the Muezin sharing the plucks of the flat indigenous Sape guitar. PSP will getting its own fighter based on the Naruto Shippuden series later this year, courtesy of Namco Bandai.


text:
The Grain and Grain Processing Information Site
Westeel's Wide-Corr series of silos, introduced in 1982, is available in commercial sizes in both flat-bottom and hopper configurations. The Super-Corr series is designed for use at grain elevators and port facilities, and features storage capacities up to 12,700 tonnes. Westeel Ltd., Winnipeg, Manitoba, Canada, also supplies bulk feed tanks and hopper bins for wet holding, seed and fertilizers; anhydrous ammonia tanks and applicators; and custom-engineered products for specialized needs.
1Chemical incident at MGP Ingredients
2Japan expects wheat production to drop significantly
3Brazil corn supplies to remain tight into 2017
4Ag product shipments a bright spot for Union Pacific
5Quality issues hurt large wheat crop in Kazakhstan
( more )
1Bunge invests in grain port
2Grain Operations: Fumigating stored grain in sealed silos
3Ocrim hosting "Wheat, Flour, And…" on Oct. 26
4Experts examine Brexit's impact on agriculture
5General Mills goes to work on E. coli prevention
1Bayer, Chinese Academy of Agricultural Sciences collaborate to improve wheat yields
to the PRINT edition, or click below for free, INSTANT ACCESS to valuable news & insights in the Digital Edition.


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Alphabetical Order: Glossary
In this glossary worksheet, students analyze sample pages from a glossary. Students complete 2 pages of questions in which topics are alphabetized and the correct page number is located.
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Opinion: Persuasive Essay Unit Introduction
Opinion, audience, purpose. Fourth graders are introduced to the three characteristics of persuasive writing in the third unit of a year-long writing program. The 98-page packet is complete with plans, model essays, graphic organizers,...
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501 Writing Prompts
Never again will you need to worry about coming up with a writing prompt! This packet contains, as it says, 501 prompts that are suitable for fourth graders on up. The prompts are paired into four categories (persuasive, expository,...
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On Target: Strategies to Help Readers Make Meaning through Inferences
Here's a resource that explicitly teaches, models, and provides readers with opportunities to practice the process of drawing inferences from text. Packed with strategies elementary, middle, and high school teachers can use, the resource...
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Summer Reading Activities
Provide parents with the tools they need to bridge the summer learning gap with this collection of fun activities. Whether it's creating an alphabet poster with illustrations for each letter, playing a game of sight word concentration,...
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Practice Book O
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[discontinued] OLD openBVE Object Editor
This project is discontinued. An open source object modelling program for openBVE, the free railway simulator. It will not have fancy effects, but the basic functionality to allow creating objects simpler.7 weekly downloads
Performance and stability4 weekly downloads
A singleplayer Snake-Game for Windows using the MonoGame Framework6 weekly downloads
Captains Game Engine
Portable game engine with main focus on point-and-click adventures5 weekly downloads
Icarus Scene Engine
3D .NET engine for Windows, Linux, Mac5 weekly downloads
Project moved / abandonned.
Project moved / abandonned.5 weekly downloads


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ISSEY MIYAKE, Billowing Pleats, campaign ad for his Spring/Summer 1985-collection photographed by Irving Penn. / Patternity
ISSEY MIYAKE, Billowing Pleats, campaign ad for his Spring/Summer 1985-collection photographed by Irving Penn. / Patternity
It's been a year since we lost the great Robin Williams.
"Carpe diem. Seize the day, boys. Make your lives extraordinary."
from Irving Penn's Flowers
Irving Penn - Bee On Lips, New York (1995)
Irving Penn / Vogue / 1995
Irving Penn: Poppy, showgirl. London, 1968
Phantom Menace costumes in Vogue. Audrey Marnay by Irving Penn & Phyllis Posnick. Vogue April 1999.
Irving Penn, The Hand of Miles Davis
New York, 1986
Peter Freuchen and his second wife Dagmar Freuchen-Gale, in a photo taken by Irving Penn in 1947. Freuchen is a top candidate for the Most Interesting Man in the World. Standing six feet seven inches, Freuchen was an arctic explorer, journalist, author, and anthropologist. He participated in several arctic journeys (including a 1000-mile dogsled trip across Greenland), starred in an Oscar-winning film, wrote more than a dozen books (novels and nonfiction, including his Famous Book of the Eskimos), had a peg leg (he lost his leg to frostbite in 1926; he amputated his gangrenous toes himself), was involved in the Danish resistance against Germany, was imprisoned and sentenced to death by the Nazis before escaping to Sweden, studied to be a doctor at university, his first wife was Inuit and his second was a Danish margarine heiress, became friends with Jean Harlow and Mae West, once escaped from a blizzard shelter by cutting his way out of it with a knife fashioned from his own feces, and, last but certainly not least, won $64,000 on The $64,000 Question.
Issey Miyake, F/W 1991 ph Irving Penn
Irving Penn (1917-2009) - Eye (for Vogue), 1982,
C-print on double weight paper (26 x 27.3 cm)
Irving Penn for American Vogue, August 1996.
Naomi Campbell and Mike Tyson by Irving Penn - Vogue December 1989
Katoucha Niane wearing YSL | ph. by Irving Penn for Vogue USA, 1988
Flowers by Irving Penn
Cigarettes / Irving Penn - 1999
IRVING PENN, Poppies (1968). Dye transfer print. / Hamiltons
15 bunny portraits in the style of the great Irving Penn: http://vogue.cm/1zSmGSP
Photographed by Noah and Daniel
ph. Irving Penn


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Winged Delite, or Mama as we've been calling her, is a very sensible mare with a smart and willing personality. She is currently schooling walk, trot,…$950
I have to sell my 2 ponies because I have some health issues and they deserve a good home with lots of care and love.$600
I have to Sell Sugar because of my health. She is a very sweet gal and deserves a great home.$400
Indiana sired yearling gelding in training, broke to saddle and walker. First Corona Home out of She My Payoff. Price negotiable$7,500
2016 Georgian Grande filly- Sired by Star Friesian Maxwell von Donius (Donius W x Nykle) and out of our Saddlebred mare Phoenix Hill's Enchanteur (Clover…$5,500
Savannah SOF- 2009 Mare, 16.1h, Maxwell von Donius (Friesian) x The Windrose (American Saddlebred). Registered International Georgian Grande, Friesian…$15,000
MGR Dahma El Ruala- 2013 Homozygous Black Rabicano Mare, 14.2h, sired by our Straight Egyptian herd sire, out of 99+% Egyptian mare. Ruala is an excellent…$5,500
MGR Monieta Al Sauda- 2009 Black Rabicano Mare, 14.1h, sired by our Straight Egyptian herd sire, out of 99+% Egyptian mare. Sauda is an excellent broodmare…$5,500


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Grizzly | Model: G6116
8-80 Magnum Mag. Base for G4850 & G6107
Price: $20.75
Grizzly G6116 - 8-80 Magnum Mag. Base for G4850 & G6107
Need it by Wed. Oct 26th?
Just order by 2:00 PM PST tomorrow and choose expedited shipping during checkout.
Optional Accessory for our G4850 and G6107 8-80 Laser Torpedo Levels.
: View All
Animation for G6116


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Franchise Opportunities in Australia: Franchises for sale, buy a franchise
Franchise for Sale
Owning your own Jim's Paving franchise business is easy. They provide you with all the training, equipment and on-going support to ensure a smooth transition into your new business opportunity. The
Price $48,870 - $77,600 + GST Approx.
Stock Included: —
Stock Value: —
Years Est: —
Gross Revenue: —
When buying a business there are lots of useful, and most often free, online resouces to assist you make a well informed decision on which business to purchase.
Australian Government Business Resources - Buying an Established Business
Business Tax Office Support website
Australian Competition and Consumer Competition website
Entrepreneurs Infrastructure Programme - Australian Government
Contact: Ryan Willsher
Phone: 08 9468 5130
Bsale ID: 75961
Agent ID: 2589037
|Perth, Perth, WA
|Franchise for Sale
This mobile business is situated in Bull Creek, Western Australia and covers the suburbs of Bull Creek, Riverton, Rossmoyne and Shelley. It is essentially a new area, but with the added value of some
|Trade Services - Home Maintenance, Plumber, Electrical
|Bsale ID 104345
|Perth, Perth, WA
|Business for Sale
For Sale: Waste Disposal and Management
|Trade Services - Home Maintenance, Plumber, Electrical
|Bsale ID 99642
|Perth, Perth, WA
|Business for Sale
Property Maintenance Services
|Building - Construction - Home Renovation | Trade Services - Home Maintenance, Plumber, Electrical
|Bsale ID 80288
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Susan Shaw
My Life in 8 Words
Author Revealed
Q. What is your motto or maxim?
A. Eat dessert first. Also: Hard work always pays off.
Q. How would you describe perfect happiness?
A. The feelings created when I'm surrounded by those I love and who love me.
Q. What's your greatest fear?
A. being alone in the world
Q. If you could meet any historical character, who would it be and what would you say to him or her?
A. Abraham Lincoln, and I'd say, "Sure wish you hadn't gone to the play that night."
Q. If you could be anywhere in the world right now, where would you choose to be?
A. Right where I am. Home. But feel free to tempt me with Tahiti or Aruba. Or a good party.


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Visa Europe has enlisted the help of UK actors Brian Blessed and Joanna Lumley to promote contactless payments through a 'Cashfree and Proud' campaign that will run from March to May. "The campaign is focused on encouraging consumers who are light contactless users, or those who are yet to use contactless in their daily lives, reassuring them of the ease and simplicity of use," Visa says. "The campaign includes ads across radio, digital, social and outdoor, at high impact sites."
- Apple Pay arriving in Germany?
- Chicago mobile ticket app hits 1m downloads
- Dubai bus passengers to get hands-free smart ticketing
- Visa works on blockchain B2B payment system
- Pizza Hut offers NFC tattoos that let customers order favourite takeaway


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Rock Band Track Pack: Classic Rock announced
Harmonix has announced the Rock Band Track Pack: Classic Rock, a bundle of 20 more tracks to help you expand your Rock Band music library.
Developed in the US for the Xbox 360, PS3, PS2 and Wii, the Track Pack will be compatible with both Rock Band and Rock Band 2, as well as all the Rock Band instrument controllers.
Songs featured include songs from mega artists like The Who, The Police, The Stone Roses and Lenny Kravitz.
The Track Pack will be available to play directly from its disc or alternatively be downloaded over Xbox Live or the PlayStation Network.
Once downloaded, the songs will automatically appear in the your custom Rock Band library, with the ability to be integrated into setlists and played in all game modes.
The complete tracklist is below:
1. Boston - Peace of Mind
2. Boston - Rock and Roll Band
3. Dead Kennedys - California Uber Alles
4. Dead Kennedys - Holiday in Cambodia
5. Free - All Right Now
6. George Thorogood & the Destroyers - Bad to the Bone
7. James Gang - Funk #49
8. Jethro Tull - Hymn 43
9. Lenny Kravitz - Let Love Rule
10. Pat Benatar - Hit Me With Your Best Shot
11. The Police - Can't Stand Losing You
12. The Police - Truth Hits Everybody
13. Rush - Closer to the Heart
14. Rush - Red Barchetta
15. Siouxsie and The Banshees - Kiss Them For Me
16. Steve Miller Band - Take the Money and Run
17. Steve Miller Band - The Joker
18. The Stone Roses - Love Spreads
19. The Who - Baba O'Riley
20. The Who - Behind Blue Eyes
The Track Pack: Classic Rock is set for release in America on 19 May for $29.99. There's been no details for Europe as yet, but we'll keep you posted.
Nintendo Switch specs and feature reveal set for 13 January
Battlefield 1 review: Military first-person shooter sets new standards
Star Trek: Bridge Crew delayed until 2017, this is what you're missing
Google Daydream View preview: The Pixel-perfect VR experience?
- Nintendo Switch specs and feature reveal set for 13 January
- Battlefield 1 review: Military first-person shooter sets new standards
- Star Trek: Bridge Crew delayed until 2017, this is what you're missing
- Google Daydream View preview: The Pixel-perfect VR experience?
- Nintendo Switch games: The games revealed so far and what we'd like to see
- Nintendo Switch: Release date, specs and everything you need to know
- Red Dead Redemption 2 trailer is amazing, watch it here
- Nintendo NX is called... Nintendo Switch: New console revealed in stunning trailer
- MVR Ascend brings virtual reality to the PS4 and Xbox One
- Enter the Xbox One S Giveaway to win this cutting-edge gaming console
- Apple MacBook Pro (2016) vs Apple MacBook Pro (2015): What's the difference?
- OnePlus 3T vs OnePlus 3 vs OnePlus 2: What's the rumoured difference?
- Microsoft Surface Studio vs Apple iMac: What's the difference?
- Microsoft Surface Book i7 (2016) vs Surface Book (2015) vs Surface Pro 4: What's the difference?
- Apple MacBook Pro (2016): Release date, specs and everything you need to know
- OnePlus 3T: Release date, rumours and everything you need to know
- DJI Mavic Pro review: One insanely powerful, portable drone
- Best Fitness Tracker 2016: EE Pocket-lint Gadget Awards nominees
- Samsung Galaxy S8 and S8 edge: What's the story so far?
- Apple MacBook Pro (2016) with Touch Bar: Thinner, brighter, faster, and very touchy feely


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LOS ANGELES - At SIGGRAPH, Vancouver's BrightSide Technologies (www.brightsidetech.com), a developer of advanced display technology for monitors and TVs, launched one of the first extreme dynamic range displays. The dynamic range of an image is the range between its brightest and darkest regions. The new display, dubbed the DR 37P, combines a matrix of LED backlights with an LCD panel to deliver 10x the brightness and 100x the contrast of conventional display products.
The new monitor is targeted specifically toward post applications. The company says the displays will initially be used in vision critical applications where customers need to see their images in vivid detail. A consumer version could follow in the future.
CHICAGO — The Mill has plans to move its Chicago studio into the landmark 1KFulton building, located in the historic meatpacking neighborhood in the West Loop. The relocation will be completed by the ...
January 26, 2016
LAS VEGAS – Linear Acoustic has announced updates for its AERO.10 and AERO.100 DTV audio processors as well as its AERO.2000 aduio/loudness manager.
April 20, 2016
LOS ANGELES — Cheryl Boone Isaacs was re-elected president of the Academy of Motion Picture Arts and Sciences (oscars.org) by the organization's Board of Governors. Boone Isaacs heads CBI Enterprises, ...
August 3, 2016


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Stuart Ramsay Tompkins belonged to the generation of scholars that came of age in Canada after the turn of the century and was tempered by the First World War. His letters to his wife, Edna, from 1912 to 1919, provide an eloquent record of his courtship and marriage; sharp observations of government and politics, both military and civil; an articulate participant's view of war in the trenches; and discerning and sensitive reactions to Siberia and China in 1919. The letters recount pivotal experiences that shaped the future professor who would become one of North America's pioneer specialists in Russian history. Edited by Doris H. Pieroth.While Edna vacationed at the lake, Stuart remained in Edmonton to help his brother Philip who was involved in the residential electrical wiring business. The following letters suggest that the courtship was of greater moment to him than to heranbsp;...
|A Canadian's Road to Russia
|Stuart Ramsay Tompkins, Doris Hinson Pieroth
|University of Alberta - 1989-01-01


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Sunnysoundisco Details
Reviews:(Based on 0 Reviews)
Sales Telephone:07869754005
About Sunnysoundisco
Hello, my name is Thomas
I am able to provide a disco for the birthday which is in hand. I my self haven't been doing discos too long, however, who I go with has been doing discos for about 20 years and he his called "Darren"
The majority of the time we do discos at hotels, but have done christenings, birthday parties, weddings and various other celebrations.
With equipment, we have everything required for this event
For qualifications, I have a degree, which I have only just got and going for an honours. The degree is: FdSc in Network Engineering, Security and Systems Administration (NESSA), which is basically computers.
I have no idea what qualification Darren has.
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Whatever your requirement, Bark will help you find local companies like
Just post your project to Bark and we'll find the most suitable companies for you.


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Stop Off in Wendover
Close to Casinos and the Bonneville Salt Flats
Visit our Super 8 Wendover hotel for great value and comfort on long or short stays. We offer comfortable, affordable accommodations, whether you are with us just one night, or you plan to stay and enjoy the area. We are within walking distance of local casinos.


text:
QUELLE PRIVILEG 3500 Service Manual
Product Reviews
There are currently no product reviews.
Reviews of our other manuals
Philippe Vareille - 2007-08-21
Good document quality, content as expected, delivery was fine. Thanks.
Heinz Preiss - 2008-02-05
You provide an excellent service. The PDF copies are very clear and easy to read. I will remain a customer.
peter aziz - 2008-02-07
is the best site i seen on the internet i visit a lot of sites it more poor and feast but this site is very good and more reliadle and kind and hope
Daniel Landen - 2008-04-01
Complete service manual and easy to read. Lots of good info in this one! Made something vintage even more valuable since it's working great! Thanks!
christos MPLIMES - 2008-04-30
Thank you for excellent sevice. This my project had stopped without you.
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We provide manuals to wide range of devices, including:
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text:
List all words that contain alacrity
Only the word alacrity was found, nothing longer.
Some random words: aegis ealdorman kors knob eke eager dhak
This is not a dictionary, it's a word game wordfinder.
- Help and FAQ - Examples - Home
Privacy and Cookies Policy - Share - © Copyright 2004-2016 Morewords.com - 80.474mS


text:
Pinterest でおしゃれアイデアをまとめましょう!
Beautiful smile~~~You can see a life well lived and a positive spirit in this woman's face. I'm sure she's had her share of heartaches and disappointments but she's lived the glass 3/4 full!
joy is skipping rope...
My people are full of joy!
This made me smile - Risas e loito. Xacobe Casal (2010) Portugal
A woman of peace from Crete. Easy to see learned peace in her face book. Peace creates beauty.


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Trip Planner : Europe / Italy / Trentino-Alto Adige / Province of South Tyrol / Bolzano / Museums / Messner Mountain Museum MMM Firmian
Messner Mountain Museum MMM Firmian, Bolzano
Categories: Specialty Museums, Museums
Messner Mountain Museum MMM Firmian is located in Bolzano. Put Messner Mountain Museum MMM Firmian and other Bolzano attractions into our Bolzano travel itinerary maker, and watch your holiday take shape.
Create a full itinerary - for free!
going to
andrea m
è un posto defilato da Bolzano, ma vicino, se avete tempo andate a vederlo!vale il luogo, il restauro ed il contenuto!!!is a place sheltered from Bolzano, but close, if you have time go see it! is the place, restoration and the content!show original
Barbara J
Wunderbare Location, die man nur schwer in einen Typus einordnen kann. Einige Exponate aus dem orientalischen bzw buddhistischen Raum. Andere, ganz klassische Ausstellungsobjekte zum Thema Berg und Be... read more »Wonderful location, one can classify difficult in a type. Some exhibits from the Oriental and Buddhist area. Other, classic exhibits on the topic of mountain and rock climbing. And in between a conglomeration of found objects. Much Corten steel, all harmoniously integrated into the Castle and the countryside. Modern architecture between the old walls. A special atmosphere with much sense of the effect of arrangements. Unfortunately not accessible and thus also difficult with stroller or wheelchair. We enjoyed especially this beautiful architecture and the big picture. And the next time we look at all the details... 10 euros per person we found appropriate.show original
...dieses Museum ist wirklich eine Reise wert. Ein wahres Labyrinth an verschiedenen Ausstellungsräumen, interessante Machart und das alles in einer alten Burgruine. Sollte man sich wirklich anschauen... read more »...dieses Museum is really worth a visit. A real labyrinth of various exhibitions, interesting style, all in an old castle ruin. Should you look at really!show original
Jøran Pecher
Awesome museum. Beautiful view of Bolzano and surrounding mountains. Great place to bring the kids. Five stars!
Andreas K.We were mainly due to the Mountain Museum there (MMM). It has been full with much kruscht and like a small labyrinth, gestaltet...wir wanted to eventually just out. Unfortunately for us a disappointment, because we expected more story of the Mahanta, what in my opinion too short coming. Those who want to learn general things about hiking and the religion is right here.show original
Sebastian OttoThe castle was architecturally beautiful size and it is very interesting to explore. Unfortunately, the Museum is crammed full, where there is too little information about the individual exhibits. It is clear no outline or a connection. It's quite nice the Messner Mountain Museum time to have seen the information content was too low for me.show original
Dominik HaberlandA museum with magnificent views of the mountains and Bolzano crafted beautifully with many details. There are many exhibits that illustrate the mountaineering.show original
Gianni ferrariVery nice museum dedicated to mountain, created from an idea by Reinold Messner ... a must see!!show original
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Work with us!
Wanaka Wastebusters Admin Manager (25 hours per week). You'll be responsible for our admin and financial systems, including monthly reporting, invoicing, GST, banking, payroll, asset management and record keeping. You will be an experienced bookkeeper, familiar with Xero and MYOB payroll. You'll …more
Dr Compost is back
Want to build a raised bed and harvest you own fresh, free vegetables? Our own gardening and composting guru, Dr Compost, can get you started, and show your how to add fertility to your garden by composting your garden and …more
Cardrona river clean-up
Friends of Cardrona River are organising a clean-up day on Saturday November 5th. Meet at the gravel road near the river (past Wastebusters) on Ballantyne Rd at 9am. Bring gloves, sunhats and something to eat and drink. Love this local initiative …more
Imagination + upcycling
What does every broken-down appliance dropped at Wastebusters dream of becoming? A raygun or Crystallion Fabriculator night light made by artist Sean Boyd. A free exhibition of his original sculptures is on now at Central Stories museum in Alexandra. If you …more
Hugh's War on Waste
Hugh's War on Waste starts on Choice TV Thursday night at 8.25pm. Entertaining and upfront – this BBC programme changed the way big UK companies look at waste, including food waste and coffee cups. Donations to the biggest food share …more
There will be a public litter pick-up around the lake-front for Keep NZ Beautiful week, organised by Don't Chuck your Muck. Meet at the Yacht Club at 10.30am on Wed 14th Sept and help keep our town looking beautiful. A big …more
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Get the Sport24 daily newsletter delivered to your Inbox!
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London - Former West Indies captain Chris Gayle is to play for Somerset in this season's domestic Twenty20 competition, the English county said on Thursday.
Opening batsman Gayle is one of the most powerful hitters in the game and he has proved especially adept in cricket's shortest format, with his 117 against South Africa in Johannesburg in 2007 the highest individual score in all Twenty20 internationals.
Gayle has also impressed in the Twenty20 Indian Premier League.
The 32-year-old, who bats left-handed but bowls right-arm off-spin, is set to fill the gap caused by the absence of West Indies all-rounder Kieron Pollard, who will be away on international duty when Somerset look to go one better after losing last season's Twenty20 final to Leicestershire.
Gayle has not played international cricket since last year's World Cup following a row with West Indies Cricket Board officials.
In a Somerset statement, Gayle said: "I am delighted to be heading to Somerset this summer, they are a great club and hopefully I can make a key contribution to their T20 campaign this year."
The west country club's director of cricket, Brian Rose, added: "Chris is a tremendously exciting player and one of the people who would get into any World T20 XI.
"Chris is a tremendous all-rounder; his batting is outstanding, he bowls and can open the attack with his off-spinners and he is also a brilliant fielder, so we are absolutely delighted."
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Property Name: DoubleTree by Hilton Grand Hotel Biscayne Bay
Property Address: 1717 N Bayshore Dr Miami, FL, 33132
Property Description: Property Location
With a stay at DoubleTree by Hilton Grand Hotel Biscayne Bay, you'll be centrally located in Miami, convenient to Perez Art Museum Miami and Port of Miami. This hotel is within close proximity of Bicentennial Park and American Airlines Arena.
Make yourself at home in one of the 202 air-conditioned rooms featuring refrigerators. Cable programming provides entertainment, and wired and wireless Internet access is available for a surcharge. Private bathrooms have deep soaking bathtubs and designer toiletries. Conveniences include desks and coffee/tea makers, and housekeeping is provided daily.
Be sure to enjoy recreational amenities, including a health club, an outdoor pool, and a sauna. Additional features at this hotel include wireless Internet access (surcharge), concierge services, and gift shops/newsstands.
Enjoy a meal at one of the hotel's dining establishments, which include 6 restaurants and a coffee shop/café. From your room, you can also access room service (during limited hours).
Business, Other Amenities
Featured amenities include high-speed (wired) Internet access (surcharge), a 24-hour business center, and express check-out. Planning an event in Miami? This hotel has 8500 square feet (790 square meters) of space consisting of conference space and meeting rooms. A cruise ship terminal shuttle is available for a surcharge.
Location Description: Near Port of Miami
Property Facts: Total Number of Rooms: 202Total Number of Floors: 4Year Built: 1985Year of Last Renovation: 1998


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Results in Oil 1990-Now Modern Paintings (1900-1979)
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Original J Jones Welsh Art Impressionist Oil Painting - The Old Barn, SnowdoniaThis is an original oil painting on canvas board by Welsh Artist J Jones. Original J Jones Welsh Art. The Old Barn, Snowdonia. This is an original painting signed by the artist and not any type of print.£10.000 bidsFree P&PEnding Today at 5:16PM BST
Original J Jones Welsh Art Impressionist Oil Painting - Old Cottage near SnowdonThis is an original oil painting on canvas board by Welsh Artist J Jones. Original J Jones Welsh Art. This is an original painting signed by the artist and not any type of print.£10.001 bidFree P&PEnding Today at 5:13PM BST
Old Vintage Oil Painting on Canvas River Landscape in Swept Gold Frame Signed£34.990 bids£3.50 postageEnding 26 Oct at 11:32AM BST
Lovely Oil Painting Of Two Brothers On Canvas , Social Realism !!!Oil on canvas of brothers signed Carl Rees.£10.001 bid£8.00 postageEnding Today at 8:20PM BST
Mix colours roses oil painting signed an datedA wonderful floral mixed roses flower arrangements fine oil painting signed on board dated 1992 by FC BROWN in a wooden wood golden gilt frame the frame Has slight mark on the top of frame but dose not effect the painting. Size 35/30cm£0.990 bids£8.60 postageEnding 24 Oct at 7:59AM BST
Sunset Study : Original Impressionist Oil Painting on Canvas : Greg Fenwick : ZGreg Fenwick is a Manchester based artist who specialises in the most atmospheric paintings. His sunrise and sunset paintings are particularly evocative. Now being avidly collected. This contemporary ORIGINAL OIL PAINTING, which is Oil on.eBay Premium Service£87.50Was: Previous price£125.00FAST & FREE
Large Oil Painting by Irene Cafieri Professionally FramedLovely large Oil Painting by known Artist Irene Cafiery Signed bottom right hand side. Size of Picture 61cm by 51cm Size of Frame 79cm by 68cm.£29.990 bids£12.99 postageEnding Today at 11:08AM BST
Large Hand Painted Modern Oil Painting On Canvas Abstract Lady With Flowers Girl£20.00Free P&P
original still life daily oil painting cherries by Natasha ArnoldA fantastic original still life oil painting painted on 7 x 5 inch artists board. Will fit a standard frame available from any retailer. Painted by Shropshire artist Natasha Arnold.£0.990 bids£2.50 postageEnding 27 Oct at 12:12PM BST
AN OIL PAINTING OF "CHURCH SPIRE" - SIGNEDSet in a brushed gold frame with tapered edges this dynamic painting captures a church tower and spire. it is surrounded by tree-tops and a church wall. A beautifully observed and executed painting.£15.990 bidsFree P&PEnding Today at 10:11PM BST
'Happy Days' Excellent original signed oil painting. Vgc.Image size approx. 14" x 9". A piece of unique artwork which is full of peace and space.£28.000 bidsFree P&PEnding 24 Oct at 5:06PM BST
20th c Oil on Canvas Painting Lake District Gold Framed Cyril Osborne PictureBeautiful Oil colour by Cyril Osborne. Title Blea - Tarn Lake District & Langdale Pikes. Measures 28" by 18" inc frame.£125.55£5.99 postage
Original oil painting of a horse in 'Summer Shade' Vgc.Image size approx. 11" x 11". A piece of unique artwork.£34.000 bidsFree P&PEnding 24 Oct at 7:31PM BST
A 20th Century oil painting in heavy gilt frameA large oil painting in a heavily carved gilt frame I bought this painting 25 years ago as I was going to put a mirror in the frame but that never happened and it went on a wall and looked the part for 25 years I have now downsized so it needs a new home the frame and painting weigh in at 18kg 4ft x 3ft are the sizes it needs a courier rather than post and that can be arranged£249.99£2.80 postage
'Early Light' Excellent original signed oil painting. Vgc.Image size approx. 14" x 14". A piece of unique artwork which is full of peace and space.£48.000 bidsFree P&PEnding 24 Oct at 5:06PM BST
Original Raquel Ferreira Oil Painting Signed 15" 11" "The Path"Oil painting full of colour and texture.£0.990 bids£7.70 postageEnding 24 Oct at 7:57PM BST
CUBEROS framed oil painting - Archway with flowers (original) purchased in 1990Original painting (one of three available). By Manuel Cuberos of Granada Spain, who had a studio in Torremolinos, Andalucia. This featured in his promotional catalogue. A beautiful Mediterranean scene of a courtyard with two arches and flowers.£24.99£7.00 postage
oil on canvas signed Clive 96 landscape oil painting ( attic find )I have no idea about this oil on canvas signed Clive 96. nice size and is ready to hang. It has been beautifully framed.£14.990 bids£11.00 postageEnding 26 Oct at 12:13PM BST
Hand Painted stretched contemporary Oil Painting on Canvas£22.950 bidsFree P&PEnding 28 Oct at 8:08PM BST
Oil painting on textured paper of a bay with boats and castle. Signed.English School late 20thC Oil on textured paper, coastal beach scene with castle in background, signed W A Giggs 1991, unframed. We have regular van trips to the Derbyshire area (via M5 and M42 services for handovers) and Devon (M5/A38/A30) and M4 (Newbury/Reading).£15.00£7.00 postage
VINTAGE K WATT FLUFFY CAT ORIGINAL SIGNED FRAMED OIL PAINTING ON BOARDMEASURING SIGNED PAINTING FRAMED 29.5 CM WIDE X 36.5 CM DOWN X IMAGE SIZE 21.5 CM WIDE X 28.5 CM DOWN (all measurements are approx.). THE FRAME IS SCUFFED AND MARKED, THERE ARE SURFACE SCRATCH MARKS ON THE PAINTING, YOU CAN SEE THEM ON SOME OF THE PHOTO'S, WHEN HANGING ON THE WALL YOU CANNOT SEE THEM, COULD DO WITH A LIGHT CLEAN,THE COLORS MAY BE SLIGHTLY DIFFERENT IN REAL LIFE DUE TO THE LIGHT AND THE PHOTOGRAPH.£59.95£16.95 postage
PAINTINGCLOUD STUDY SIGNED ANDREW NICHOLLS AND DATED 06. SIGNED BACK AND TITLED "HIGH SUMMER CLOUD." UNFRAMED. COULD BE HUNG AS IS. SIZE 12 X 20 INCHES. NO CONDITION ISSUES. I KNOWLEDGE NOT HINGE ABOUT ARTIST BUT PAINTING IS VERY ATMOSPHERIC AND DISPLAYS WELL.£7.500 bids£6.75 postageEnding Today at 5:15PM BST
Portrait of a curious cow original oil painting canvas Gordon Bruce new UK artAll sides of the canvas are painted. Latest cow paintings. The canvas is ready to hang no need for framing.£80.00FAST & FREE
Hand Painted Period Style Oil Painting on Canvas£19.950 bidsFree P&PEnding 28 Oct at 8:08PM BST
Hand Painted Period Style Oil Painting on Canvas£19.950 bidsFree P&PEnding 28 Oct at 8:08PM BST