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"The gut microbiota enhances the host's metabolic capacity for processing nutrients and drugs and modulates the activities of multiple pathways in a variety of organ systems," says Sandrine Claus of the Imperial College of London, a researcher on the study.
Claus and her colleagues exposed germ-free mice to bedding that had previously been used by conventional mice with normal microbiota and followed their metabolic profiles for 20 days to observe changes as they became colonized with gut bacteria.
Over the first 5 days after exposure, the mice exhibited a rapid increase in weight (4%). Colonization also triggered a number of processes in the liver in which sugars (glucose) are converted to starch (glycogen) and fat (triglycerides) for short-term and long-term energy storage. Statistical modeling between liver metabolic functions and microbial populations determined that the levels of glucose, glycogen and triglycerides in the liver were strongly associated with a single family of bacteria called Coriobacteriaceae.
"Here we describe the first evidence of an in vivo association between a family of bacteria and hepatic lipid metabolism. These results provide new insights into the fundamental mechanisms that regulate host-gut microbiota interactions and are of wide interest to microbiological, nutrition, metabolic, systems biology and pharmaceutical research communities," says Claus.
Another important finding in the paper, according to Claus, is that gut colonization strongly stimulated the expression and activity of the cytochrome P450 3A11, an essential enzyme in drug-detoxification pathways.
Although she warns about being careful to extrapolate the specific findings from mice to humans, Claus notes the results of this research will provide a basis to further develop new strategies to beneficially modulate host metabolism by altering microbial communities in the gut.
mBio® is a new open access online journal published by the American Society for Microbiology to make microbiology research broadly accessible. The focus of the journal is on rapid publication of cutting-edge research spanning the entire spectrum of microbiology and related fields. It can be found online at http://mbio.asm.org.
Jim Sliwa | EurekAlert!
Further information:
Further reports about: > Coriobacteriaceae > Glucose > drug-detoxification pathways > fundamental mechanism > glycogen > hepatic lipid metabolism > pharmaceutical research > triglycerides
Aquaculture: Clear Water Thanks to Cork
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Bioluminescent sensor causes brain cells to glow in the dark
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Physicists from the University of Würzburg have designed a light source that emits photon pairs. Two-photon sources are particularly well suited for tap-proof data encryption. The experiment's key ingredients: a semiconductor crystal and some sticky tape.
So-called monolayers are at the heart of the research activities. These "super materials" (as the prestigious science magazine "Nature" puts it) have been...
Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.
This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...
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Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
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#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017
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Submarine Museum
A Concorde arriving on a barge to the USS Intrepid Aircraft Carrier on the Husdon River in Manhattan. Ph. by Seth Holladay
USS Nautilus. A wonderful submarine museum for the family to enjoy explore. Ask me about my visit. https://www.facebook.com/CarrieBryniakKingdomMagicVacations?ref=hl
Very Rare WWII Enigma Cipher Machine. This highly important three-rotor Enigma deciphering machine was used by the Nazis during World War II. It is believed that acquisition of an Enigma, and the subsequent deciphering of the German codes by the Allies, shortened the war in Europe by at least two years. Examples of Enigma machines are exceptionally rare and almost all known models are in museums.
Battleship Texas...
Panzer I tank now on display in the German Tank Museum Munster Germany
a very poignant image...it took the great ship 15 minutes to reach the ocean floor.
Cheeky chap: During his visit to the Royal Naval Submarine Museum, Gosport, Prince William said it was lucky Prince George was not here. 'I think he'd get up to all sorts of mischief pulling on things,' he said
HMS Hood in the Panama Canal Zone July 1924
USS GROWLER DIESEL POWERED SUBMARINE 'INTREPID SEA, AIR and SPACE MUSEUM' NEW YORK
HMS Belfast 2for1 when you go by train. Once home to a crew of up to 950 men, HMS Belfast, part of Imperial War Museums, tells the stories of those who lived and worked on board this warship during the Second World War and beyond.


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BRIEF-Knowles qtrly earnings per share $0.24
* Knowles reports Q3 2016 financial results and provides outlook for Q4 2016
* PM Ivanishvili says his work done after beating Saakashvili
* Garibashvili seen easily approved by parliament
* Prime minister post now most powerful in country
By Margarita Antidze
TBILISI, Nov 2 Georgia's prime minister on Saturday proposed his close ally, Interior Minister Irakly Garibashvili, to succeed him when he steps down in the next few weeks.
Billionaire Bidzina Ivanishvili has said he will quit as premier after Georgy Margvelashvili is sworn in as president on Nov. 17. The prime minister's position is now the most powerful in the former Soviet republic under constitutional changes which transferred many of the president's responsibilities.
Garibashvili still has to be nominated by parliament and approved by Margvelashvili, but both steps are a formality as Ivanishvili's Georgian Dream coalition dominates the assembly and the president is an ally of Ivanishvili.
Margvelashvili was elected last month to take over from pro-Western Mikheil Saakashvili, who spent a decade in power.
The election cemented Georgian Dream's grip on power, putting it in charge of the presidency for the first time, as well as the government and parliament which it took control of in a parliamentary election in October last year.
Ivanishvili says the departure of his bitter rival, Saakashvili, means his job is now done, two years after entering politics following a business career in which he made a fortune estimated at $5.3 billion.
But he could continue to wield influence as he dominates politics in the South Caucasus country of 4.5 million, which fought a five-day war with Russia in 2008 and is crossed by pipelines that carry Caspian oil and gas to Europe.
The current government must resign after the inauguration. The parliament then has one week to agree on a nominee for post of prime minister, to be appointed by the president.
Ivanishvili, who will be acting premier during that week, will hand over his functions on Nov. 24 and a new cabinet will be proposed by his successor, to be approved by parliament.
* Knowles reports Q3 2016 financial results and provides outlook for Q4 2016
* Biodel announces adjournment of annual meeting until Thursday, October 27, urges stockholders to vote
Oct 24 Visa Inc, the world's largest payments network operator, reported a 27.7 percent rise in quarterly profit as customers spent more using the network.


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He be smokin that whizcrank.
ayon kay antonio 123 ika-22 ng Nobyembre, 2007
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Search pmfloyd1's books
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The plague by Albert Camus
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Three Bedrooms in Manhattan (New York Review Books Classics) by Georges Simenon
Saint Leibowitz and the Wild Horse Woman by Walter Miller
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Versus Versace is the diffusion line of famed Italian fashion house Versace, created for those with a strong sense of individual style. Creative and unconventional, Versus Versace is known for its distinctive 'rock-chic' style. Created in 1989, the label was re-launched in 2009 with the help of Christopher Kane, and is now headed by Anthony Vaccarello, with Donatella Versace remaining in the role of artistic director.
Shop Versus Versace bags at MyBag now. Free next day delivery available.
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Versus Versace Women's Metallic Clutch Bag - Red
Was £265.00
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Versus Versace Women's 'Versus' Shoulder Bag - Black
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Versus Versace Women's Belt - Black/Silver
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bacsisoft_pOps (Symbian) Publisher's description
from getjar.com
This is my fisrt handy game
This is my fisrt handy game. You have to dodge the red circles with the little blue fish.
- High Score storage
- Music (machinae supremacy -hero, MIDI)
- Control with the number-keys, quit with star
Need 176x176 pixels screen at least!
System Requirements:No special requirements.
Program Release Status: Minor Update
Program Install Support: Install and Uninstall


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H-E-B Back to School Sweepstakes (Expired)
Enter the H-E-B Back to School Sweepstakes for a chance to win $2,500, $2,500 for your School, and a VIP meet and greet with Brec Bassinger!
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ONE (1) FIRST PRIZE: $500 H-E-B gift card. ARV: $500.
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ONE (1) THIRD PRIZE: H-E-B Back To School Bundle consisting of a backpack; a lunch kit; four (4) binders; three (3) notebooks; two (2) 150 count packs of paper; one (1) 10 ct. of markers; one (1) 12 ct. color pencils; one (1) pair of scissors; one (1) 4 oz. glue stick; and ten (10) folders. ARV: $100.
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Bladensburg Drywall Contractors
The drywall Bladensburg, MD has to offer is certainly a viable option when you are trying to decide which material you want to build with. Whether you are going to be building a new home, an addition to an existing home, or a commercial building of some type, you will definitely want to look into all of the benefits drywall has to offer. One of the best things about this particular building material is that it is fire-resistant, so you don't have to worry about it feeding the flames if one happens to break out.
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Layhill Drywall Inc14208 Alderton Rd Silver Spring, MD 20901
Georgetown Decorators LLC11005 Havenpark Dr Silver Spring , MD 20902
Proper Care Decorating & Painting Inc.904 Helena Dr. Silver Spring, MD 20901
Compton's Painting & PlasteringWashington, DC 20001
Home Improvement Etcetera2117 Young St. SE Washington, DC 20020
Quality Painting & Plastering508 E Indian Spring Dr Silver Spring, MD 20901


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Totes, Travel, Weekender, Red & Pink Tote Bag
Shipping Included Shipping & packaging provided by seller. Learn More
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- Exterior scuffs or marks
Exterior faint stains. Only visible up close.
Used. Please inspect photos. Victoria Secret's very large open tote. 21 inches wide with 14.5 inches wide base. 10 inch handle drop. There are few black scruffs throughout exterior and on left side and towards front area over Vic rhinestones on exterior, there are faded stains (only noticeable up close). There is minor wear on exterior base corners otherwise no rips or tears. Interior is very clean. There is 1 small mark on interior on 1 side. Overall the bag is still in great condition and usable. The stains and black marks do not show up that great in the photos so please inspect photos closely before buying. Email me if you have any other questions. Thanks!
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I am actress, still trying to make my foothold strong in Bollywood. I had made a debut in Bollywood in 2004 but that went unnoticed and I moved on to south industry.
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Ash Grunwald, Trouble's Door
Australian bluesman Ash Grunwald releases his brand new album Trouble's Door this month.
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The follow-up to his 2010 award-winning release Hot Mama Vibes, this record captures the changes that have occurred in Grunwald's life over the last two years.
Moving from his hometown of Melbourne for the warmer climes of coastal NSW with his wife and young daughter, Grunwald busied himself building a new home studio, the birth place of Trouble's Door.
His most reflective record to date, Trouble's Door documents Grunwald's heartfelt political frustrations. 'It's some of my most personal song writing,' Ash says. 'I had just done a benefit gig to stop coal seam gas mining.
There were other issues going on at the time, you can take your pick really, and it occurred to me that our system just doesn't work. We are experiencing the result of rampant unchecked capitalism.'
Inspired by music from an early age, it was when Grunwald starting jamming the blues with his grandfather that the seeds of his passion for the genre took hold.
Releasing his debut album Introducing to an enthusiastic audience, Grunwald went on to win the hearts of fans across the country with his dynamic live shows.
Touring Trouble's Door nationally, Grunwald's stopping in Darwin to play the Darwin Blues Festival on Friday 29th June at the Gardens Amphitheatre.
Trouble's Door from Ash Grunwald is our Album of the Week on ABC Local Radio across the Territory.
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Hotels Close to The Opium War Museum, Humen
Hilton Garden Inn Shenzhen Bao'an
No. 529 Xin Sha Road, Bao An District, Shenzhen 5181254.0 out of 5.0
Located in Bao'an, this hotel is 1.2 mi (1.9 km) from Shajing Citizen Square and 2.5 mi (4.1 km) from Sanpin Cultural Square. …
Sheraton Dongguan Hotel
S256 Provincial Highway Houjie Town, Dongguan 5239624.5 out of 5.0
This family-friendly Dongguan hotel is located in the entertainment district, within 3 mi (5 km) of Dongguan Houjie Hospital, …
Parklane Hotel
222 Dezheng Road, Dongguan 5238434.5 out of 5.0
Located in Chang'an, this luxury hotel is within a 10-minute walk of Chang an Square and Chang an Park. Lotus Mountain and …
Mels Weldon Dongguan Humen
Huanghe Tower, Humen Avenue, Humen Town, Dongguan 5239004.5 out of 5.0
Located in Humen, this luxury hotel is within 1 mi (2 km) of Humen Park, Humen Square, and Broadway Fashionable Mall. The …
Grand Noble Hotel
No. 121, Humen Road, Dongguan 5239074.5 out of 5.0
Located in Humen, this luxury hotel is within 1 mi (2 km) of Humen Square, Broadway Fashionable Mall, and Humen Park. The …
Lucky Holiday Hotel
No. 888 Huangpu Road West, Guangzhou3.5 out of 5.0
Located in Tianhe, this hotel is within 3 mi (5 km) of Tianhe Park, Guangzhou Library, and Guangdong Museum. Tianhe Stadium …
Hyatt Regency Dongguan
Song Shan Lake Central Dist, Dongguan 5238084.0 out of 5.0
Located in the business district, this family-friendly hotel is within 6 mi (10 km) of Tamrac Opera House, Dalingshan Park, …
Pullman Dongguan Forum
32 Dong Cheng Zhong Lu, Dongguan 5231294.5 out of 5.0
Located in the heart of Dongguan, this luxury hotel is within 3 mi (5 km) of Dongguan Stadium, Dongguan Exhibition Hall, an …
Baolilai International Hotel
Fu Yong Road, Fu Yong Town, Baoan Dist, Shenzhen 5181035.0 out of 5.0
Located in Bao'an, this luxury hotel is 1.8 mi (2.9 km) from Phoenix Mountain and within 12 mi (20 km) of Fuyong Ferry …
Pullman Dongguan Changan
NO.38 Jinghai Zhong Road, Dongguan 5238624.5 out of 5.0
Situated in a rural location, this luxury hotel is within 9 mi (15 km) of Chang an Square, Chang an Park, and Songgang Park …
- Haiyatt Garden Hotel Houjie
- Kande International Hotel
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Meaning of "baker" - Learner's Dictionary
(Definition of "baker" from the Cambridge Learner's Dictionary © Cambridge University Press)
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a large, round vegetable with hard, yellow or orange flesh
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Auke Bay Temporary Employment Agencies
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'Sarah' speaks for spooked Fulham boss Rene Meulensteen after complaint over Ravel Morrison comments
- January 23, 2014
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After receiving a complaint from the Premier League accusing them of tapping up West Ham's Ravel Morrison, Fulham boss Rene Meulensteen is spooked.
So spooked that he dare not speak the midfielder's name for fear of further repercussions, so he had club spokesperson, 'Sarah' speak on the matter on his behalf.
In a mildly comical scene, Sarah then had to intervene once more for Meulensteen, who really wasn't for turning, and might as well has slapped an apple gag in his mouth such was the unlikelihood of him speaking about Morrison.
Watch the slightly bizarre behaviour from Fulham boss Meulensteen on the clip below.
Grab more information on: FulhamRavel MorrisonWest Ham
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Tuas Power Generation Pte Ltd
We are a leading power generation company and a key provider of electricity solutions, multi-utilities and environmental services. Backed by the strong support of our parent company, China Huaneng Group, we have also established TP Utilities which will build a world class Multi-Utilities Complex in Tembusu industrial area of Jurong Island. We invite individuals who envision a successful and fulfilling career to join our dynamic team of professionals by submitting your application for the following position.
Accounting Officer
jobsDB Ref. JSG400003002987112
- Perform accounts receivable duties, including liaising with business units for preparation of invoices to counterparties and customers
- Carry out bank reconciliation and prepare GST returns
- Handle petty cash claims and provide support for month-end closing activities
- Diploma in Accountancy with a minimum of 1 to 2 years of relevant experience
- Proficient in Microsoft Excel
- Knowledge of SAP Accounting System will be an advantage
This position is based at Somerset.
Interested candidates, please forward your resume, quoting the reference number of the position you are applying for and stating your expected and current salaries to:
Vice President
Human Capital Management
Tuas Power Generation Pte. Ltd.
111 Somerset Road #13-06
Singapore 238164
By way of your application, it is deemed that you have consented to the company's collection, disclosure and storage of your personal information in accordance with the Data Protection Act.


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The new home of
7 reviews
Nestled on a hillside, surrounded by the beautiful countryside of Raby Estate's land, guests will find that Oscar's Barn offers far reaching views of the North York Moors to the east and the Pennines to the west. Perfect for walkers, cyclists and guests wanting to really explore the local area there are numerous established public footpaths through the surrounding woodland and countryside. Ideal for guests wanting to enjoy a quiet romantic break or for guests wanting to travel with friends or family, Oscar's Barn can be booked as a separate property to sleep two people or along with a separate annex to sleep a total of four guests. Part of a larger property, which dates back to 1750, the accommodation has been furnished to a very good standard. Worthy of the VisitEngland 4* Gold Award, the property is well-presented throughout with excellent quality furnishings, contemporary features and appliances, as well as a travertine tiled floor in the kitchen - yet also manages to retain all of the original character and charm with exposed original beams and features. The separate annex can be accessed by crossing the small courtyard area and is also exceptionally well-furnished and offers guests a private bedroom and living area, its own fridge with freezer compartment, along with a superb bathroom. The sought after location offers guests peace and tranquillity and makes an ideal touring base with nearby mainline railway station and easy access to main roads. Oscar's Barn is situated on the border between County Durham and Teesdale which grants any visitor easy access to a broad range of sights, attractions and activities. For that perfect romantic break with guests wanting to treat themselves, there is a Michelin starred restaurant just over a mile away in the small village of Summerhouse. Just 2½ miles away from the historic Roman village of Piercebridge, guests will be able to enjoy a visit to the ancient Roman fort, as well as stopping off at one of the local pubs and restaurants. The contemporary market town of Darlington is only 6½ miles away and offers plenty of shops and eateries. Raby Castle and Deer Park are 7 miles away and are not to be missed. Set in the heart of the Durham Dales, guests will be able to explore the castle and its beautiful 200 acre deer park. Barnard Castle and Richmond are both easily reached and lie 14 miles away, offering historic attractions including Bowes Museum, Barnard Castle and Richmond Castle, as well as local farmer's markets, tea rooms, shops and boutiques. The historic cathedral city of Durham is only 16 miles away making Oscar's Barn the perfect location for guests wanting to visit friends and family who are studying at the university or to book ahead for graduation ceremonies. A little further afield but still within an easy 1½-hour drive, guests will be able to visit the Yorkshire Dales, North York Moors, Durham Dales and Yorkshire Coast. Shop, pub and restaurant 2½ miles.
12 open-tread steps to entrance. All on first floor: Living room with double bed (6ft zip and link, can be twin) and beams. Kitchen with breakfast area and travertine floor. Bathroom with shower over bath and toilet. Annex: Ground floor: Living room. 1 double bedroom (5ft zip and link, can be twin). First floor: Bathroom with Jacuzzi bath, shower cubicle and toilet.
Gas central heating, (NSH in annex), gas, electricity, bed linen and towels included. 32'' Freeview TV. DVD. CD. iPod dock. Gas hob. Electric oven. Microwave. Washing machine. Freezer. Wi-fi. Lawned garden with patio, terrace, sitting-out area and furniture. Summerhouse. Gas barbecue. Parking (2 cars). Natural water supply from spring. Welcome pack. No smoking. No children under 12 years. NB: Deep pond in grounds 100 yards.
11 reviews
Nestled in the tranquil country lanes of the village of Mickleton, this warm, stone, terraced holiday cottage dates back over 150 years, with a cottage garden. It has traditional charm, including beams, open stonework, a multi-fuel burner and is well-furnished. The cottage is situated in the unspoilt and beautiful Northern Dales, designated an 'Area of Outstanding Natural Beauty'. This location is ideal for touring the Northern Dales, Yorkshire Dales and the Lake District. Locally, the small market town of Middleton-in-Teesdale has everyday shopping, traditional inns serving food and tea rooms selling local specialities, as well as a pub serving hot food all week. The countryside offers good walking, fishing and cycling. Shop 2 miles, pubs and restaurant 50 yards.
Ground floor: Living room. Dining room/kitchen with laminate floor. Separate toilet. Beams throughout. First floor: 2 bedrooms: 1 double (5ft), 1 twin with sloping ceilings. Bathroom with roll-top bath, toilet and sloping ceiling.
Multi-fuel burner in living room (initial fuel included). Oil central heating, electricity, bed linen and towels included. Travel cot. High chair. Freeview TV. DVD. CD. Electric cooker. Microwave. Washing machine. Dishwasher. Small garden with patio, sitting-out area and furniture. Portable barbecue. On road parking. Cycle store. No smoking.
6 reviews
Mill Stone Cottage is well presented and furnished to a good standard throughout and is ideal for families, couples and friends who enjoy holidaying together. Full of character, charm and original features, guests will find a cosy living room with a multi-fuel burner, beams and comfortable sofas. On the first floor guests will find a comfortable en-suite, double bedroom that is very well presented and with super views extending out towards the dales. There is also a twin bedroom and a super family bathroom with a feature bath, heated towel rail and plenty of original features that fit well alongside the practical touches. Outside, guests will have use of a patio area with an outdoor table and chairs to relax on those sunny days.Perfectly situated in the village of Wolsingham, Mill Stone Cottage is the ideal place for guests who want to really explore this beautiful part of the country. Often referred to as the 'Gateway to the Dales', the conservation village of Wolsingham is situated in picturesque Weardale, in the North Pennines, and is part of a designated Area of Outstanding Natural Beauty. Offering three welcoming, local pubs serving food, as well as a good choice of cafés and local shops selling a range of goods, Wolsingham is a popular destination for guests of all ages. The cottage is situated right at the heart of the village where all the amenities are within easy walking distance of the front door. Perfect for walkers, cyclists and ramblers wanting to explore the Durham Dales and North Pennines, guests will find plenty of established local footpaths, cycle routes and bridleways which lead directly from Wolsingham and into some of the most spectacular countryside that the area has to offer. The popular town of Stanhope is only 6 miles away, and guests really must take a visit to the Durham Dales Centre where there is plenty of specialist information regarding walks, cycle routes and local area history. As a great base for guests wanting to really explore the local area, Mill Stone Cottage really is the ideal spot. Wolsingham lies only 16 miles away from the cathedral city of Durham, where guests will find plenty of historic attractions including the cathedral and castle, as well as a variety of boutique shops, cafés, bistros and tea shops. Ideal for those wanting to enjoy a romantic break as there are plenty of riverside walks, street festivals and artists, theatre, cinema and leisure centre in the heart of the city. Great too for visiting friends and family at any of Durham University campuses. The lead mining museum in Killhope, 20 miles away, is another popular attraction and shows the history of how lead was mined by generations of miners who lived in the Weardale area. Bishop Auckland is just 12 miles away and will be hosting the spectacular, 'Kynren – an epic tale of England' during the summer of 2016. Newcastle upon Tyne, the Metrocentre, Barnard Castle, Derwent Reservoir and Alston, which is the highest market town in England, can all be reached within an hour's drive. A little further afield but still within an hour and a half driving distance, guests will be able to take a day trip to the Lake District, Northumbria, Hadrian's Wall, Middleton-in-Teesdale and the spectacular, High Force Waterfall, which is the highest in England. Shop 250 yards, pub and restaurant 100 yards.
Ground Floor:Living room: With multi-fuel burner, 32" Freeview TV, DVD player, beams and wooden floor.Kitchen/dining area: With gas hob, electric oven, microwave, fridge, dishwasher, washing machine, beams and tiled floor.First Floor:Bedroom 1: With double bed and en-suite with shower cubicle, toilet and heated towel rail.Bedroom 2: With twin beds.Bathroom: With bath, shower attachment, toilet and heated towel rail.
Gas central heating, gas, electricity, bed linen, towels and Wi-fi included. Initial logs for wood burner included, remainder available locally. Welcome pack. Patio with garden furniture. Bike store. Private parking for 1 car. No smoking.
3 reviews
Situated in the small town of Shildon, Freville Cottage is a traditional terraced house that has been decorated and renovated throughout, transforming it into an ideal holiday home. Its great location lends the property to guests wanting to really get to know County Durham and the North East. Perhaps the most popular attraction in Shildon is the National Railway Museum. When coupled with its counterpart in York, these museums make up the biggest railway museum in the world, providing a complete picture of the 300-year history of the railway.Just 2.5 miles away from the thriving market town of Bishop Aukland, guests will find many enjoyable attractions nearby. Well-known as the 'Gateway to Weardale', Bishop Auckland stands high above the meandering River Wear, commanding impressive views over the surrounding countryside and beyond. There are a number of great places to eat and drink in the town, as well as a selection of boutiques and high street shops. Perfect for walkers, cyclists and ramblers, the tracks and trails leading directly from Bishop Aukland take in such sites as Auckland Castle, the country residence for over 900 years of the historic Prince Bishops and their deer park. The Auckland Way Railway Path is an equally popular route. Head to the market town of Barnard Castle for some of the arts in action. There's a restored theatre/events hall called the Witham, and the French chateau-like Bowes Museum is home to an impressive collection of European curio. For guests who enjoy visiting historical monuments and churches, there is Escomb Saxon Church, and if that isn't enough, then Durham's World Heritage sites surely will be. Durham is an ancient city with a vibrant atmosphere, thanks to its teeming student population. There's a wealth of attractions and places to explore in and around the city, regardless of its striking cathedral and castle. For more sporty holiday goers, the nearby county cricket club and Durham's golf club won't disappoint. A little further afield but still easily accessible are the magnificent North Yorkshire Dales and the North York Moors National Parks. Other attractions in the area include the Angel of the North statue, the Beamish Museum, Newcastle and the Metrocentre. A little closer to home is Raby castle, a fine example of medieval architecture that has a 200-acre deer park that's ideal for picnicking and taking a stroll. Shop ½ mile, pub and restaurant ¼ mile.
Ground Floor: Living/dining room. Kitchen. Wooden floor throughout. Separate toilet. First floor: 2 bedrooms: 1 double (5ft), 1 twin (can be 6ft double). Bathroom with shower over bath and toilet.
Electric coal-effect fire in living room. Gas central heating, electricity, bed linen and towels included. Electric cooker. Microwave. Wi-Fi. Enclosed yard. Parking (1 car). Welcome pack. No smoking.
0 reviews
Situated in the picturesque Weardale Valley, an Area of Outstanding Natural Beauty and a UNESCO European and Global Geopark, Tulip Cottage offers fantastic views across some of the most scenic countryside that the county has to offer. Located high up on the hillside and surrounded by working farmland, this semi-detached holiday property is beautifully renovated and furnished to a very good standard, and is in a great location for exploring the area. It is ideal for guests who enjoy a walking or cycling holiday, and there are plenty of public footpaths and cycle paths that lead directly from the cottage through some of the most magnificent countryside and beyond, offering visitors views of hills, dales, waterfalls and much more. There are also plenty of attractions within a close radius, which include Killhope Wheel, the Lead Mining Museum which is a favourite with families of all ages, Alston Railway with its steam locomotives, the Weardale Polar Express at Christmas, the National Railway Museum at Shildon and the Beamish Open Air Museum. For guests wanting to travel a little further afield but still remain within an easy hour's drive, the opportunities are vast. The cathedral city of Durham, with its castle and university, is only 27 miles away, whilst Cumbria and the Lake District can be visited within an hour's drive, as can Northumberland, Hadrian's Wall, Newcastle-upon-Tyne, Alnwick and Hexham, a historical market town with an Abbey. Shop and restaurant 3 miles, pub ¼ mile.
Ground Floor:Living room: With open fire, Freeview TV, DVD player, CD player and stone tiled floor.Kitchen/dining room: With electric oven, electric hob, microwave, fridge, freezer, washing machine and stone tiled floor.First Floor:Bedroom 1: With kingsize bed.Bedroom 2: With double bed.Bathroom: With bath, shower cubicle and toilet.
Oil central heating, electricity, bed linen and towels included. Initial fuel for open fire included. Travel cot, highchair and stairgate. Welcome pack. Enclosed garden with sitting-out area and garden furniture. Parking for 2 cars. No smoking.
24 reviews
This elegantly furnished and spacious detached bungalow is only a ten minute walk from the Beamish Living Museum. Set at the head of a small quiet cul-de-sac, it is ideally located to discover the delights of Durham, the Dales, and Northumberland's sweeping sandy beaches and famous castles, offering a combination of tranquil countryside, vibrant city life and historical sites. The open air living museum of Beamish is a short walk away. Woodland View looks over to the woods from the rear and sitting in the peaceful conservatory is perfect for relaxing after a day exploring the idyllic Beamish Valley, beautiful woodlands and cycle paths. Sustrans coast to coast cycle track runs right by the woods to the rear and there are delightful walks from the door. The surrounding villages are full of friendly country pubs. Only a 10 minute drive takes you to The Riverside International Cricket Ground; home of Durham Cricket team, and with the Metro Centre only 20 minutes and the coast around 30 minutes. The property is within a mile of Beamish golf course and under 2 miles to a municipal golf course. This is an ideal holiday location for exploring the whole of this unspoilt area. Shop ½ mile, pub and restaurant ¼ mile.
1 step to entrance: All on ground floor: Living room with French doors/dining room. Kitchen with breakfast area. Conservatory. 2 double bedrooms. Bathroom with clawfoot bath, shower cubicle and toilet. Separate toilet.
Electric coal-effect fire in living room included. Gas central heating included (£30per week, £25 per short break November-March). Electricity, bed linen and towels included. Cot. High chair. Five Freeview TVs. DVDs. CD. iPod dock. Electric cooker. Washing machine. Tumble dryer. Dishwasher. Fridge/freezer. Wi-fi. Enclosed lawned rear garden with patio, sitting-out area and furniture. Front garden. Parking (2 cars). Cycle store. Welcome pack. No smoking.
13 reviews
Enjoying a peaceful working farm setting, and views from its secure garden, this converted single, storey stable block is of an excellent standard. Visitors are welcome to roam across 120 acres of open farmland, with an abundance of wild birds, an amazing 64 species, making it a twitcher's paradise. Young children will delight in the play area and outside toys, as well as a visit to see the resident goats. Mainsforth is a small, picturesque village just 7 miles from Durham and its magnificent cathedral, fine amenities and riverside walks. Beamish Open Air Museum, the Lakes, Yorkshire Dales and Northumberland's sandy beaches are all easily accessible.
All on ground floor. Living/dining room/kitchen. 2 bedrooms: 1 double, 1 twin. Bathroom with shower over bath and toilet.
Gas central heating, electricity, bed linen and towels included. Travel cot. High chair. Freeview TV. Video. DVD. Stereo/CD. Microwave. Washing machine and tumble dryer in shared laundry room. Wi-fi. Enclosed garden with patio and furniture. Barbecue. Parking. Children's play area. No smoking.
7 reviews
Situated in the popular market town of Barnard Castle, the properties at 10 Newgate are the ideal base from which to explore the local and surrounding areas. Perfect for business guests, families, friends, couples and single guests, there is an ample choice of accommodation to suit each guest and fulfil their requirements. Each property at 10 Newgate offers good quality, comfortable and practical accommodation. There is a choice of property depending on the guest's requirements. All named after local attractions and historic buildings, there are many personal touches throughout, making Newgate a real home from home. Raby (ref 31097) and High Force (ref 31098) are both 2-bedroomed apartments that sleep 4 people. Each have 2 double bedrooms, as well as a comfortable living room and well-equipped kitchen with good quality appliances. Hamsterley (ref 31101) is a 1-bedroomed property with a double bedroom. Fully self contained, there is a small kitchen, living room and family bathroom with ample space for 2 guests. The Market Cross (ref 31099) is a quirky property which is an 'upside down' building with the 2 double bedrooms on the ground floor and a large living room and kitchen on the first floor. Once again there are good quality bathroom facilities and many personal touches. Both The Museum (ref 31096) and The Castle (ref 31100) are perfect for guests who want to enjoy comfortable, practical accommodation. The space has been well used to provide a comfortable sleeping area that has been cleverly screened off from the living room and kitchen area by the careful placement of the furniture and wardrobe. These two studio apartments are perfect for guests who would like a little more space and facilities than a standard hotel room in the area. 10 Newgate is located behind a local pub at the heart of Barnard Castle, and guests will be able to leave their car behind to take a leisurely stroll into the town centre, with many top class pubs, restaurants, inns and cafés that line the old fashioned high street. There is also a weekly farmers market that provides local produce, arts, crafts, food and drink, and several boutique and gift shops that are scattered throughout the town. At the end of Galgate is Scar Top and the ruins of the stone castle date back to 1125 and gives the town its name. The castle also overlooks the River Tees and offers magnificent views over the surrounding areas. A little further afield but still within only a few miles distance, guests will find the pretty picture-postcard village of Staindrop, which is set in a dedicated Area of Outstanding Natural Beauty and is definitely worth the short trip out to visit. Perfect for walkers, cyclists and nature enthusiasts, Barnard Castle is set amongst some of the most magnificent countryside that the county has to offer. There are many public footpaths, established walks and cycle paths that lead through the town, alongside the River Tees and out into rolling countryside and beyond, towards places and attractions including Binchester Roman Fort and Raby Castle, as well as many National Trust houses and sites. The cathedral city of Durham is only a 30-minute drive away and is perfect for guests wanting to include a theatre break into their stay, a romantic boat ride along the River Wear, a meal out in one of the bistros and restaurants, boutique shopping or the opportunity to visit the famous cathedral and Durham Castle, which is steeped in history and tradition. Durham is a city that is thriving all year round and offers free on street entertainment on a regular basis including the annual book week, Lumiere Festival, jazz festival, art festival, miners gala and many more. For those wanting to travel a little further afield, guests will find all the majesty and beauty of both High Force and Low Force waterfalls or be able to explore the ...
Stairs to entrance. All on first floor: Living room/kitchen. 2 double bedrooms, one with en-suite shower room and toilet. Bathroom with shower over bath and toilet.
All properties: Gas central heating, electricity, bed linen and towels included. Travel cot. High chair. 42" Freeview TV. iPod dock. Electric cooker. Microwave. Public car park (permit provided for weekly bookings, short breaks £1.50 per day).
Peacefully set amid the rolling countryside of a 200-acre sheep farm, this collection of cottages has been converted from the old farm stables, bakery and dairy, have their own individual character and retain many of their original features. The tranquil location makes this the perfect place to relax and unwind while the many footpaths and cycle routes are an excellent way to enjoy the surrounding countryside and views. Situated on the Durham/Northumberland border, Derwent Grange is ideally located for exploring the many attractions both counties have to offer. The historic city of Durham, with its magnificent cathedral and river boat trips, the market town of Barnard Castle with its 12th-century castle, and medieval Raby Castle are all just a short drive away. The award-winning Beamish Open Air Museum is just 13 miles away, and is well worth a visit. Newcastle and Gateshead offer an array of museums and art galleries along with excellent shopping and are only 18 miles away. The breathtaking scenery of the Northumberland National Park is within half an hour's drive as is Hadrian's Wall. A little further afield are Alnwick Castle and Gardens while the castles and gloriously unspoilt coastline of Northumberland are around an hour's drive. Shop and pub serving food 1 mile.
All on ground floor: Living room. Dining room. Kitchen. 1 double bedroom with additional bunk. Shower room and toilet.
Gas central heating included. Cot. Table-top oven with two ring hob. Shared garden.
All properties: Electricity, bed linen and towels included. High chair. Freeview TV. CD. Microwave. Washing machine and tumble dryer in shared laundry room (at cost). Garden and furniture. Barbecue. Private parking for 2 cars. Private water supply.
7 reviews
This delightful barn conversion retains its rustic charm standing in an elevated position with wonderful panoramic views overlooking the Wear Valley and the Pennine Fells beyond. Adjoining the owner's cottage and another holiday property, in unspoilt countryside of the Durham Dales. A good central base, the Lakes, Dales, Borderland, Barnard Castle, Hexham, Newcastle and Durham, within 30 miles. Shop and pub ½ mile. Can be booked with ref 13874 to sleep 6+2.
Ground floor: Living/dining room. Kitchen. First floor: 2 bedrooms: 1 double (four poster) with en-suite shower room and toilet, 1 bunk. Shower room with toilet.
Solid fuel central heating (coal at cost). Oil central heating, electricity and bed linen included. Cot. High chair. DVD and small library. Electric cooker. Microwave. Washing machine. 24hr drying service. Freezer space available. Wi-fi. Garden and furniture. Ample parking. Natural water supply from spring. No smoking. NB: There is a stone banked area and drop in the garden.
8 reviews
All on ground floor: Living room. Kitchen. 2 double bedrooms, one with en-suite shower room and toilet. Bathroom with shower over bath and toilet.
Perfectly nestled in the rolling countryside, on a working farm, bordering North Yorkshire and County Durham, The Cottage at Wilson House offers guests peace, tranquillity and the surrounding stunning views. Adjacent to the owner's home, yet retaining a level of privacy, guests will find the cottage welcoming, cosy and full of character. Perfect for walkers and cyclists, there are numerous established public footpaths and cycle paths within the surrounding local area which will lead guests through beautiful countryside, open fields and unspoilt woodland. Perfect for an afternoon stroll, guests will find a CAMRA approved local pub only a mile away, as well as numerous others within an easy 15-minute radius.Ideally situated for exploring the magnificent Yorkshire Dales, The Cottage at Wilson House is close to Teesdale, Swaledale and Arkengarthdale, which are becoming increasingly popular places for cyclists and walkers to explore and enjoy. Only 5 miles away from the historic market town of Barnard Castle, guests really must take a trip to the famous Bowes Museum as well as the old castle ruins. For guests wishing to travel a little further afield, there are excellent transport links along the A66 and the A1M. The cathedral city of Durham can be reached within an hour's drive north, as well as the historic city of York in the opposite direction. The beautiful hills and fells of the Lake District are also only just over an hour's drive west and to the east guests will find the fabulous beaches and coastline of Whitby and Saltburn by the Sea.Perfect for couples wanting to enjoy a romantic break or friends wanting to share their holiday accommodation, there is a private courtyard and hot tub for guest's use from which views of the surrounding countryside can be admired and enjoyed, as well as an outdoor seating area and BBQ. The Cottage at Wilson House has two double bedrooms on the ground floor, each with an en-suite shower room. On the first floor, is an open plan kitchen/dining room and living area that really takes advantage of the surrounding views. Well equipped, welcoming and full of character, The Cottage at Wilson House really is the ideal destination at any time of year. Shop 5 miles, pub and restaurant 1 mile.
Ground Floor:Bedroom 1: With double bed and en-suite with shower cubicle and toilet.Bedroom 2: With double bed and en-suite with shower cubicle and toilet.First Floor:Open plan living space: With beams and wooden floor.Living area: With 28" Freeview TV.Dining area.Kitchen area: With Rayburn, microwave, fridge, freezer, washing machine and tumble dryer.
Oil central heating, electricity, bed linen, towels and Wi-Fi included. Welcome pack. Enclosed garden with sitting-out area, garden furniture and barbecue. Hot tub. Private parking for 3 cars. No smoking. Please note: No children under 12 years old.
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cottages.com is a trading name of Wyndham Vacation Rentals (UK) Ltd. Registered in England and Wales.
Registered Office: Spring Mill, Stoney Bank Road, Earby, Lancashire,BB94 0AA, UK
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Washington: US officials banned all Samsung Galaxy Note 7 smart phones from airplanes on Friday.
The U.S. Department of Transportation (DOT) held meeting with the Federal Aviation Administration (FAA) and the Pipeline and Hazardous Materials Safety Administration (PHMSA) regarding the fire hazard and banned all Samsung Galaxy Note 7 gadgets.
US official directed that anyone possessing Samsung's recalled handsets while traveling by air may face fines and the devices would be confiscated.
Samsung, the South Korean electronics giant, has recollected all Note 7 phones, following the reports of numerous injuries because of exploding batteries and fires. The production of flagship handset has also been stopped due to this issue.
US Transportation Secretary Anthony Foxx said that the ban will be effective on Saturday, October 15, 2016.
According to the agency, the passengers possessing Note 7 will be denied boarding, in hand luggage or in checked baggage on domestic flights and international flights to or from the US.
Anthony Foxx said in a statement, "We recognize that banning these phones from airlines will inconvenience some passengers, but the safety of all those aboard an aircraft must take priority."
He also added that this additional step has been taken to avoid any in-flight fire incident because even one would pose a high risk of severe personal injury and put many lives at risk.
According to the agency reports, Samsung had received at least 96 reports of the US handsets overheating including 13 reports of burn injuries and 47 incidents of property damage.
Samsung has offered refunds or replacement of devices after facing this issue, and is paying an extra $100 credit to those customers who want to exchange the Note 7 for another Samsung device.


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Spanish murderer stages shock jailbreak
Alex Dunham · 15 Jul 2013, 14:21
Published: 15 Jul 2013 14:21 GMT+02:00
- Prison guards face rap for napping at work (15 May 13)
- Prison guards see double in big brother breakout (02 May 13)
- Police car thief exposes handcuffs defect (22 Mar 13)
The prisoner, doing time for murder and sex crimes, was aided by two accomplices who were waiting for his arrival at Principe de Asturias hospital in the town of Alcalá de Henares, near Madrid.
Police believe the men were alerted by the prisoner's family, who had previously received a call from Alcalá Meco penitentiary as required by Spanish protocol.
CCTV footage showed the criminal's two partners in crime in the hospital grounds prior to the prisoner's arrival.
Their objective, as would soon become all too clear, was to distract the officers escorting the prisoner to allow the jailbird to fly free.
Once the prisoner had been uncuffed and had his arm put in plaster, the policemen accompanied him back to the police car parked outside the health centre.
But as soon as they stepped onto the hospital's emergency ramp they were faced with a brawl between the prisoner's accomplices.
The officers at first hesitated and when they finally decided to intervene they were pushed to the ground by the two men.
The prisoner then hit the officers on the head with his plaster and escaped in a BMW that had pulled up right next to the scuffle.
A manhunt is now underway while the officers who accompanied the prisoner are being investigated.


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This Wen Product Is Amazing! I Seen Results In Just One Wash! I Will Use This Product As Long As I live I Recommend This To Every Woman And Man :)
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Build web apps that scale, create engaging mobile apps, and integrate simply. All app types rely on the scalable and flexible Web App platform which allows developers an optimized full life cycle experience from app design to app maintenance. The App Service capabilities allow developers to focus on their code and reach a stable, highly scalable production state quickly. With the API and Logic App features, developers can build real-world enterprise applications bridging barriers between business solutions as well as on premise to cloud integration.Sponsored Listing
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Scooby-Doo! Moon Monster Madness - DVD
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It's one giant step for dog-kind as Scooby-Doo and the Gang blast off for an epic, other-worldly adventure in this all-new original movie! After winning the last 5 seats in a lottery, Scooby-Doo, Shaggy, Fred, Daphne and Velma are off to space in billionaire Sly Baron's brand new ship, the Sly Star One. It's all gravity-free fun until a mysterious alien begins destroying the ship! As the ship breaks down, the crew is forced to land on Sly Baron's base... on the dark side of the moon! Will the gang unravel this alien mystery? Will Scooby-Doo and Shaggy find snacks on the moon? Will Fred ever take his space helmet off?! Journey to the outer limits with Scooby-Doo to find out!
- Rated PG: Some scary scenesÂ
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Ceramic Straighteners£24.99 instead of £127.92 (from Proliss) for ceramic flat iron straighteners - save 80%
Save 80%
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- Tame your mane with ceramic straighteners.
- Valid in black, hot pink leopard, white zebra, purple zebra, pink zebra or peacock.
- Straighteners feature ceramic plates & adjustable temperature.
- Creates slick, smooth 'dos.
- Or twist for loose curls!
The Fine Print
- May buy multiples.
- Voucher valid until 18th Feb 2014.
- Delivery costs an additional £4.99 per item.
- Please allow up to 10 working days for delivery after redeeming.
- Subject to availability.
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Leave bad hair days firmly in the 80s with this deal fit for a queen....
We're offering you ceramic straighteners in a choice of styles for only £24.99, saving you up to 80% off Proliss' price of £127.92 (correct as of 30.1.14).
Perfect for taming frizz, straightening mad curls and making you look a million dollars, Proliss' ceramic straighteners are a must-have in every girl's beauty kit. Available in your choice of black, hot pink leopard, white zebra, pink zebra, purple zebra or peacock, the straighteners feature 100% ceramic plates and a handy LED indicator light. You can even adjust the temperature to suit you, whilst the 8' swivel cord allows you to move around with ease whilst styling. To create loose, bouncy curls, simply twist your straighteners as you move them slowly down each strand of hair. After a spritz of spray, you and your mane are ready to go!
Please note that the products come with a US plug fitted with a UK adapter.
How to Redeem
- When the deal ends we'll send you your unique wowcher code.
- Head to the Wowcher redemption page using the link we send you.
- Quote your full wowcher code.
Once purchased, you can redeem this wowcher towards another wowcher or claim a Wowcher Wallet Credit. Click here for more info.
Revitalising Spa Day with Massage for 2 - Over 30 Locations!£64 instead of up to £99 for a spa day for two with a 25-minute chocolate, Swedish or bamboo back, neck and shoulder massage - save up to 35%
Zippos Halloween Circus Ticket, Brent Cross£9.95 for a side view ticket to see Zippos Circus, or £10.75 for a front view ticket - save up to 46%
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Cute white paws, pretty white teeth, I look great in a bow tie, I even have blue and brown eyes… let me be Frank… I'm adorable! And quite Frankly, you should adopt me! My name is Frankie! I am a 1.5 year old, 12 lb, Shih tzu mix. I love playing fetch, belly rubs, lounging on the couch, and hanging out with other dogs. I would prefer to be in a home without any children, and I might need a few days to settle into a new family, but I would love to have a doggie sibling! Let's be Frank… you know you want me, Frankie! Contact our Adoption Coordinator today!
100 Oaks Petsmart
The second Saturday of every month 10 AM to 2 PM
Thank You!
Your message has been sent to Agape Animal Rescue.
You'll receive a copy, too, at to help you keep track of which pets you've inquired about, and which shelters and rescues you've emailed.
NOTE: Some shelters have physical locations you can visit; some of these shelters may only have pets for a limited time, so please do not wait for a reply—just go visit the shelter! Other organizations are rescue groups run by busy volunteers who may take a while to reply. You can find information about the shelter or rescue group caring for this pet, and their adoption procedures, on the pet's details page on Adopt-a-Pet.com.


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Atlantic to Toulouse
Sorry, couldn't find any routes from Atlantic to Toulouse!
places to visit in Toulouse
Toulouse Walking Tours
Places To Visit
Ophorus Toulouse Sightseeing Day Tours
Places To Visit
Canal de Brienne (Le)
Nature / Wildlife
Museum of Toulouse / Museum of Natural History / Botanical Gardens
Church of Les Jacobins
History & Culture
Musee Saint-Raymond - Musee des Antiques de Toulouse
restaurants in Toulouse
That's one long tiring journey, but I'll help you make it better!Oh before I forget, it's cold out there, so protect yourself.
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