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Date: 1893 ca.
Description: The Goetsch sisters sit and stand in two rows on the family farm. They are wearing dark dresses. Names: (back row) Martha G. Buelke, unidentified, Lydia; (...
Date: 2000-03-24
Description: "The Boondocks is just North of Mayville on City. Tr. V. Carly & Parker Hren are our guests." The restaurant sign reads, "best fish fry in the country." Fr...
Date: 2004
Description: The Budahns, with their dog Dexter, pose in front of another barn on their property. The last time cows were milked here was in 1988.
Description: Jack and Bev Hoepner live at N8931 Hwy AY (Section 8).
Date: 1908 ca.
Description: The Alexander Krueger family posing with a Deering Binder being pulled by a three-horse team through a field. Florentina, Jennie, and Alexander stand behin...
Date: 1978-05
Description: Auction of old items at the Weber Brewery.
Date: 1910 ca.
Description: Sarah Krueger sitting next to an engraved wooden memorial in Kripplein Christi cemetery.
Date: 2000-05-19
Description: "Feil's Supper Club, which has a German motif, is just south of Randolph on Hwy 73." From left to right; Ralph "Buddy" Ruecker, Ralph Widmer, Shirley Widme...
Date: 1955
Description: "This is a 1950 Studebaker. Critics dubbed it a 'two row corn picker!'"
Description: Pastor Mark Berlin has served the "River Church" for two years. His eight-year-old daughter's name is Julie.
Date: 1948
Description: "Ruth Zirbel."
Description: Jennie, Edgar, and Alexander Krueger posing bareback on horses. They are lined up to face the left, spaced in a row. The horses wear horse collars, blinder...
Date: 1903
Description: Johanna, Jennie, Edgar, and William Krueger husking corn in a cleared cornfield. Corn shocks are scattered around the field. Farm buildings are in the far...
Description: An unidentified woman standing next to an engraved wooden memorial in Kripplein Christi cemetery.
Description: Members of the Krueger family sitting in a boat at the shoreline about to launch into the quarry pond. Sarah Krueger sits in the end of the boat, while Flo...
Date: 1996-09
Description: "This is Theresa Station. Note the Rock River and Soo Line Railroad track."
Description: Scott, Grace, and Ryan ride in a tractor on the Batterman farm.
Description: David Huettner and wife, Karen, milked the last cows in 1998.
Date: 1900 ca.
Description: View down unpaved street towards the old part of town. Several horse-drawn carriages are parked on both sides of the street. A group of men, women and chil...
Date: 1901 ca.
Description: Outdoor portrait of three unidentified women posing at the side of a house next to a log stump that is fashioned into a chair. One of the women sits in the...
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Feminist Abortion Network Inc
Rating: 5 stars 6 6 reviews
106 E E St Yakima WA 98901 USA
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GreatNonprofits badges allow you to raise awareness of your favorite nonprofits on your own web sites!
Reviews for Feminist Abortion Network Inc
The Feminist Abortion Network, or FAN, is a collective of the Fourteen remaining non-profit feminist based abortion care providers in the US. The work of these providers in their communities in providing patient centered care is the historical roots of feminist health care. The scope of care delivery for each clinic is based in specific community needs and culminates in a national impact on quality abortion care.
Due to the lack of a national presence for these independent feminist clinics, FAN was formed to represent the unique strengths, tenacity and diversity of these providers in the larger ecosystem of abortion care providers. Many of the original feminist clinics that opened in the early seventies to address the lack of abortion care post Roe v. Wade have closed over the years. FAN is committed to keeping our remaining member clinics open to serve the true needs of the vulnerable and historically marginalized communities, still not adequately served in our country. And to represent our consituents on a national level
More Feedback
I've personally experienced the results of this organization in...
Since working together with FAN to collaberate, create national strategies and to share resources we have more of a sense of the feminist roots that have initiated and sustained abortion care access to marginalized populations. The formation of FAN is fairly new, but the ideals and values among the members are the true basis of reproductive justice and the inspiration to many who have worked in this area of health care for decades.
If I had to make changes to this organization, I would...
Because the tasks of running clinics that provide abortion care can be all consuming in this political climate, FAN would benefit from having resources and personnel to focus specifically on the collective activities. Currently it requires additional work on the part of clinic staff to carry out FAN efforts, and can place a strain on these smaller organizational structures.

subset: commoncrawl


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Unlimited Online Storage for October 2016
Anyone who works with large photos, videos or work files can benefit greatly from unlimited online storage. Just a few years ago, the idea seemed ridiculous. But as file sizes continue to bloat and high speed internet speeds up, unlimited online file storage is becoming a high-demand service. Even better: the prices for unlimited file storage have dropped sharply over the past few years.
Here are our top 3 unlimited online storage picks:
|Cheap, Easy-to-use
|14 days
|Great options
|14 days
|Simple to learn
|14 days
About Unlimited Online File Storage Services
Finding a place to store large files can become a difficult and expensive challenge in itself. A large collection of big files requires big hard drives, expensive external hard drives or an obscene number of DVDs. The physical storage space alone can cause problem for file storage – not to mention the cost of purchasing and maintaining storage equipment.
The same challenges also plague people who need to share large files. If you have ever tried to send a large file over e-mail to someone, you probably already know how difficult that can be. E-mail attachment limitations and time-outs make it pretty much impossible to e-mail large files to other people. Unlimited online file storage can be used to share files of any size with anyone you want.
Best Unlimited Online File Storage Companies
The best unlimited online storage backup companies are the ones listed right on this page. We have ranked these companies in order of our preferences, but they are all high quality places to store important files. The key to choosing one of these companies is to consider your needs and then compare the top file storage sites.
There are several things we consider when choosing the best unlimited file storage companies:
- Security
- Pricing plans
- Reliability
- File storage features
We place the highest priority on security when ranking unlimited online file storage sites. People don't store files that they don't care about. No matter how much space a data storage company offers, we always place security at the top of the list. Once the security measures have been established, we then move down the list to come up with our rankings.
Prices of Unlimited File Storage
The prices of unlimited online backup storage space can vary by a wide range depending on which company you join and how much storage space you actually use. Some storage companies offer unlimited space for a flat monthly fee while others charge based on how much space your files occupy each month. As long as you stick with a reputable storage company, the prices you pay for storage will be reasonable.
Pure backup services tend to offer the lowest prices for unlimited online file storage. Companies such as Carbonite give you unlimited storage for a flat fee. You do not pay per gigabyte or anything like that. It's just a flat fee and you get as much data as you need. However, the catch is that you can only back up the data from one computer. The most storage space you will get from a pure backup company is limited to the size of your hard drive.
Other storage services such as those that let you store files from any computer and sync files across multiple computers tend to go with a pay-as-you-use payment plan. A common pricing plan that we see at these file storage sites is something where everyone gets a few gigs free and then pays $0.15 per gigabyte used after that. These storage companies are the most flexible, but they can become expensive if you actually end up storing large amounts of data.
Free Unlimited Online File Storage
Believe it or not, free unlimited online file storage does exist. There are several free services out there that give you as much storage space as you need without charging you a thing. There are restrictions (of course) that may or may not cause problems.
Let's talk about the top free unlimited online storage services and explain how they work. If these companies are not what you need, I also have recommendations for cheap unlimited file storage services that might work better.
1. Mediafire.com
Mediafire is a barebones file hosting service that gives all users unlimited storage space. The biggest drawback to using Mediafire is that you are limited to files of 200 MB or less. Additionally, you cannot store files for the long term. And finally, you have to view a splash screen before you can download your files.
Mediafire works well for temporary file storage, but the 200 MB max file size is a major limitation. The splash screen may also be a turnoff if you share files with clients or coworkers. Paid versions of Mediafire remove these restrictions, but the cheap services listed below give you more features and better pricing plans.
2. CrashPlan
CrashPlan is a free service that backs your files up to other computers that you own or to external hard drives. I'm not sure if you can consider CrashPlan a true free unlimited online file storage plan because it does not back up files to the cloud. It only backs them up to other computers.
If you have computer savvy friends, you can invite them to join your CrashPlan account. You and your friends can then back up files to each other's computer. This option allows both of you to use offsite backup without paying for it. The biggest limitation to CrashPlan is that it does not store your files online. You cannot access remote files unless both computers are on and connected to the internet.
Almost Free Unlimited Online Storage
The above two options work well for very specific purposes, but they both have big limitations. My personal preference is to pay a little money for true unlimited online file storage. The pricing plans for these services are affordable for almost any budget.
Best (almost) free unlimited online storage companies:
- ZipCloud
- Backblaze
- Carbonite
These three tools all have pricing plans that go as low as $5 a month. You can store as much data online as you want and never have to worry about being charged for extra storage. There are no limitations to how much space you can use.
There are two major advantages that these almost free unlimited online storage tools offer over the others listed above. The first: you can store, download and share your files as often as you want. There are no storage limitations or download limitations.
The second advantage is that these tools are easy to use. All you have to do is install the backup software and the tool will work in the background to back up your data. You do not have to manually upload and download files with these tools.
Bonus advantage: these online file storage tools come with additional features such as direct download links, file syncing and simple file sharing. The low prices and additional features make these services a great value for anyone with data storage needs.


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Raising toddlers can be challenging but Oh so much fun! Join us in the Toddlers group--get advice, share your knowledge and meet other moms like you. Hope to see you there!
¸.•´¸.•*´¨) ¸.•*¨)
(¸.•´ (¸.•` ¤ The Wineaux Chateau*´¨)
Join us! http://www.cafemom.com/group/117182
We aren't just a group about wine - Come see what we have to offer ^
Hi! Welcome to CafeMom!
Please join us in the 20 Something Moms group. It's a really great place to get started here and meet other moms like you.
I hope to see you there!
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Celeb Snaps! Hottest Star Sightings – Friday 10.19.12
Loraine Pavich
| October 19, 2012 - 5:11 pm
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Maria Menounos
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Sous chef promoted to executive chef at 8-twelve
Andrew Miller, who joined 8-twelve MVP Bar & Grill in Brookfield as sous chef at its opening in summer, has been named the restaurant's executive chef.
He replaces Rafael Elisea, who returned to his position as head chef at Graffito South in Florida. Both restaurants are owned by the SURG group. »Read Full Blog Post
Milwaukee Symphony Orchestra, actors know how to do drama
Drama, drama and more drama were on the program for the Milwaukee Symphony Orchestra's performance Friday evening in Uihlein Hall.
Guest conductor Rossen Milanov led the orchestra through a program bracketed by Mendelssohn's "Overture" to "A Midsummer Night's Dream" and selections from Prokofiev's "Romeo and Juliet," joined by a quartet of actors. »Read Full Article
Things to do in Milwaukee this week
Bewitching hour
No one turns into a pumpkin at "Midnight in MKE," the Skylight Music Theatre's season launch party at 8 p.m. Friday at the Wherehouse, 818 S. Water St. The season will be filled with fairy tales and fantasy — from Rossini's "La Cenerentola" to "The Wizard of Oz" — and the party will reflect some of that fun. La Prosette, sometimes known as Anja Notanja Sieger, will take typewriter in hand and help attendees write their own fairy tale ending. Partygoers may also think they have a fairy godparent when they win some magical jewels from Lizzibeth. Everyone will feast on treats savory and sweet from Kasana and Indulge. Buy a ticket online at www.skylightmusictheatre.org for $15 or at the door for $20. Partygoers must be 21 or over. »Read Full Article


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Offizielle State of Alaska Reiseinformationen
Take your itinerary with you using our My Alaska Trip feature and the TravelAlaska app.
Zu My Alaska Trip
South Thane Road
Visit Website
Airport Rd
1803 Old Steese Hwy N.
Sort by region:
Inside Passage
Mining Juneau's history. Venture underground. Pan for gold. Museum/gift shop. Email firstname.lastname@example.com.
Catch "gold fever" and experience what it was like to seek your fortune during Gold Rush days!
Step back in time to an 1890's tent city - laugh 'till you cry as our cast of sourdoughs and dance hall girls entertain you with hilarious melodrama. Pan for gold and keep all you find! All-you-can-eat outdoor feast of grilled wild Alaskan salmon, a host of other delights, live entertainment. Gift Shop. .
Relaxing resort, great hospitality & activities: historic gold dredge, museum & active mine tours, recreational gold mining/panning, kayaks. Cozy cabins ($90+), RV park (20/30 amp) & tent camping ($16+), cafe, espresso bar, extraordinary gift shop, showers, free WiFi & firewood. National Historic Site. Located in the center of town. email@example.com.
Bring the family for a fun-filled adventure aboard the Tanana Valley Railroad and ride into gold mining and pipeline history. Ride the train, visit the dredge and receive a brief but informative course in mining. Then you will try panning for yourself. You will find gold - we guarantee it! Mid-May through Mid-Sept.
Fordern Sie den kostenlosen offiziellen State of Alaska Reiseplaner an.
Unsere Alaska Fotos
Alaska Adventure Cruises - Order Your Free Brochure!


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Ashburn, VA Change Location >
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Rory Golden 3'6" x 5'6" Rug
Ships direct from vendor. Allow 4-6 weeks for delivery. 96606692
Bold, bright looks define the playful Rory rug. Woven of recycled vintage silk saris, this vibrant rug tells a unique green story. Rendered in a beautiful shade of golden yellow, no two are exactly alike, offering a truly one-of-a-kind way to brighten any setting.
Polyester-Silk Blend
Rory Golden 3'6" x 5'6" Rug Dimensions
42L x 66W


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Welcome to Glock Talk
Why should YOU join our Glock forum?
- Converse with other Glock Enthusiasts
- Learn about the latest hunting products
- Becoming a member is FREE and EASY
If you consider yourself a beginner or an avid shooter, the Glock Talk community is your place to discuss self defense, concealed carry, reloading, target shooting, and all things Glock.
my left hand is sore
Discussion in 'General Firearms Forum' started by vinstang67, Mar 12, 2013.


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How to Track Empty Search Results in Google Tag Manager
...When You Can't Edit the Site!
Level of difficulty: 3.5/5
Have you ever wondered if people are searching for things on your website and getting NO RESULTS back?
If there's anything that says to a potential customer that you can't help them, it's [...]


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About Us
Key Financial Group, LLC brings independent, unbiased advice and guidance to our clients and families. With more than 35 years combined industry experience, Jason A. Jennings, CERTIFIED FINANCIAL PLANNER™ and David M. Morders, Chartered Retirement Planning Counselor (CRPC)®, puts our clients needs first… Read More
Financial Services
Latest Blog Post04/5/2016
Jason Jennings and David Morders of Key Financial Group Recognized as Top Financial Advisors by LPL Financial
Frederick, Maryland--March, 30, 2016--Jason Jennings and David Morders, LPL Financial-affiliated advisors at Key Financial Group announced today that they have ... Read More03/17/2016
Will Eight Be Great For The Bull?
The bull market turns seven. Last Wednesday, on March 9, 2016, the bull market officially celebrated its seventh birthday. During that ... Read MoreView All Blog Posts View News


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Toshiba Satellite L855-S5155 Notebook PC - 3rd generation Intel Core i5-3230M 2.6GHz, 6GB DDR3, 750GB HDD, DVDRW, 15.6" Display, Windows 8 64-bit, Silver - PSKFUU-06X003Item#: T78-156114 | Model#: PSKFUU-06X003
Currently Out Of Stock!
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Toshiba L855-S5155 15.6" Core i5 750GB Notebook Product Details
Toshiba Satellite L855-S5155 Notebook PC
Achieve your computer tasks using the Toshiba Satellite L855-S5155 Notebook PC. This silver colored notebook PC incorporates the power of 3rd generation Intel Core i5-3230M 2.6GHz processor with the efficiency of 6GB DDR3 memory to deliver supreme computing performance with great speed. You can store tons of files and access them whenever you want using its huge 750GB HDD storage capacity. It also boasts 15.6" Display which delivers rich visuals to enlighten your multimedia entertainment. Using its DVDRW, you can read and write several disc formats, including CDs and DVDs. In addition, the Windows 8 64-bit operating system is installed to this PC for enhancing its features. Grab the Toshiba Satellite L855-S5155 Notebook PC today!
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Related ItemsPrevious
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Warranty provided by: Toshiba Laptops
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Shipping Weight: 7.0000 pound(s)
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- Toshiba logos are registered trademarks of Toshiba. All others trademarks and copyrights mentioned herein are the property of their respective owners.


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Halo 4
Msheridan1990 4 years ago#1
ok here r the rules 2 the game
1. u hav 2 say sumthin nice about me LOL e z rite? im prolly the best halo player on this bord n im prolly the best contributer 2 this bord 2 so this shuld b e z 2 do
2. u hav 2 tell me y u dont have a code and how cool i would b if I gave u a code jus bcuz im curious LOL
3. the winners will b whose replyes i like the most this is not 1st come 1st serve
4. i do not kno how many replies in i will give it out but it will be within a couple hours
so lets play kids ROTFL or else i mite jus give them 2 my cat LOL
lol I like this guys topics
cyborg9 posted...
lol I like this guys topics
GT: Metal Lloyd
I am not up for marrying Christmas.
I grow tired of the foolish foolery of foolish fools.
bananasandwich1 4 years ago#5
Msheridan1990 posted...
2day is december n i am n the giving mood LOL so i was thinking about something nice n i was thinkin im prolly the best halo player on this bord (top 3 n the world) so i am going to make a christmas game and i hav 2 spec codes i will give 2 the 2 winers LMAO sounds like fun mirite
Son, you just went full retard
KingOfAsia 4 years ago#6
dat msheridan lol
add me to xbox live, Mr Possum, Cute girls. only please
Well well well... You Msheridan1990 are clearly the best halo player around town. You could demolish me in and outside of game, as well as every one else here. I also very much appreciate the fact that you gave me the forest hazop skin. That was mighty super fine of you. Infact, your cat is probably more worthy of those specialization codes than I am. I bet your cat could even destroy me in halo!
As for why I don't have a code yet, I can't even say myself. There have been a lot of conflicting issues going on over at the Waypoint forums, and Microsoft is incompetent to say the least. Emailing codes disguised as xbox live gifts was a horrible idea anyways... What a waste!
Merrry Christmas best person evar! ...heh that good enough for ya? :P
White FC [Panda]: 3783 - 6584 - 4908
White 2 FC [Liz]: 2666 - 9974 - 6792
BurnsDepartment 4 years ago#8
Tip for everyone; say something sarcastic and horrible to him. You can easily pass it off as nice. This will save a small portion of your withered soul if you resort to flattering this troll in order to gain codes.
+1 bananasandwich1. And why is TC always laughing in every post? He's rolled on the floor laughing so much by now I'm surprised the friction didn't result in his house catching on fire.
GT: Metal Lloyd
originlucario9 4 years ago#10
Dude, you are best halo player on this ste, and whoever says not they can suck your d***. I also won't get the code since my account was on teen not adult so I won't be getting the spec code. And I really want pathfinder.
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E-commerce Website Redesign
This project received 97 bids from talented freelancers with an average bid price of $600 USD.Get free quotes for a project like this
Skills Required
Project BudgetN/A
Total Bids97
Project Description
We need expert and talent web site designer to re design our web site,
1. E-commerce with shopping cart,
2. current content can be migrated to new site;
3. current back links will be re-directed to new site;
4. SEO friendly design; onpage seo can be easily done;
5. Unique, attractive design;
6. With social media buttons;
7. search filter function;
8. products configuration.
Please bid with suggestion plan and time frame. Current url and e.g sites will be provided.
Looking to make some money?
- Set your budget and the timeframe
- Outline your proposal
- Get paid for your work
Hire Freelancers who also bid on this project
Looking for work?
Work on projects like this and make money from home!Sign Up Now
- Forbes
- The New York Times
- Time
- Wall Street Journal
- Times Online


text:
Welcome to Credit Institute of Canada -
The Conestoga chapter has been a proud member of the Credit Institute since 1966 and our goal is to continue to support our community and grow our membership. We are advocates of the Credit Institute and will continue to do so by promoting the most reputable, sought-after professional association and authority in credit education.
Members, we would like to congratulate our most recent graduate Hassanatu Timbo
The decision to go back to school or to choose a new career path as an adult can be a daunting decision. You need the support of your family and at times your employer.
Please help us congratulate Hassanatu Timbo on her most recent scholastic achievement! Below is a message from Hassanatu.
I currently work as the Credit & A/R Coordinator at MTD Products Ltd, where I support the MPP Division and have been for the past 2 years, prior to this I worked at John Deere Credit Inc., in Burlington for 3 years, though on a contract , but on a continued basis. I have held several positions in the Accounting/Finance field for the past 7 years and when I joined MTD in 2011, was given the opportunity to study for the CCP program, it has greatly improved my business skills; enabled me to bring clarity and many risk management skills to my current role.
I couldn't say this as well as the author Steve Maraboli.
Make a pact with yourself today to not be defined by your past. Sometimes the greatest thing to come out of all your hard work isn't what you get for it, but what you become for it. Shake things up today!
Hassanatu, we congratulate you on all the success that you've earned by achieving your CCP designation.
Katrena Tucker, on behalf or the Conestoga Chapter.
© 2010-11 Credit Institute of Canada - Conestoga Chapter | Email: email@example.com


text:
About AlyssaSugarIce : I'm Alyssa. Do you need to know more? Well, I don't think you do, so that's all you need to know. :p
AlyssaSugarIce's FML badges
Consolation prize
Your FML was denied. We had to at least give you a badge to cheer you up a bit.
Up and coming moderator
It's nice of you to help us sort out the submissions, using FML's moderate feature.
The rules are the rules
Reading the comment rules is a really good idea. This badge is sponsored by our moderating team.
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Loan Center
Auto Loans
If you're in the market for a new or new to you automobile, come to the credit union for financing.
We typically offer a better option than a dealer because dealer financing often is for a shorter term, resulting in high payments.
If the dealer offers a rebate plan, consider taking that instead of their low-rate financing. Add the rebate to your down payment and apply for a credit union loan. The larger down payment will reduce the amount you need to finance.
Questions? Contact us! Or if you're ready to finance or get pre-approved, apply online!
Auto Loans
Other Loans
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text:
Lundin Petroleum shares sink in Stockholm trading after the oil explorer cut resource...
Lundin Petroleum shares sink in Stockholm trading after the oil explorer cut resource expectations for the giant Johan Sverdrup discovery off Norway. A Swedbank analyst says the reduced outlook is "clearly negative and undoubtedly below market expectations," adding it also was negative news for Sverdrup partners Statoil (STO) and Maersk Oil.
From other sites
Video at CNBC.com (Apr 22, 2016)
at CNBC.com (Jan 15, 2015)
at CNBC.com (Jan 5, 2015)
at CNBC.com (Dec 15, 2014)
at CNBC.com (Dec 11, 2014)
ETF Hub
ETF Screener: Search and filter by asset class, strategy, theme, performance, yield, and much more
ETF Performance: View ETF performance across key asset classes and investing themes
ETF Investing Guide: Learn how to build and manage a well-diversified, low cost ETF portfolio
ETF Selector: An explanation of how to select and use ETFs


text:
Other projects made by So Sew Easy:
Offer some kudos...
Join the conversation...
Ask a question...
Add your comment...
What was your source for this sewing project?
Online Photo or Website
Name of website or photo Project Pattern
What advice would you give someone starting this project? Please read my blog post to find out more - how you can join the group board and contribute to the collection. http://so-sew-easy.com/a-gazillion-free-sewing-patterns/ If you offer a free sewing pattern here on Craftsy or on your blog - please pin it to the Pinterest board for us all to enjoy. Or just follow the board to keep up to date with all of the patterns being posted. The Group board is here: http://pinterest.com/debycoles/free-sewing-patterns/
pattern for mens bow tie
I will work on them! Thanks for the suggestion.
I Think That's pretty nice of you, especially for those who can't afford to buy them.
Thank you!
Have you heard of home made incontince pds?
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Tosa native among independent film award nominees
The Spirit Awards, which are the independent film world's equivalent of the Oscars, announced its nominees for 2012 Tuesday. Wauwatosa native Michael Raisler is the producer of one of the best picture nominees, "Beasts of the Southern Wild."
The winners will be announced Feb. 23. »Read Full Blog Post
Katy Perry; Motorhead; Trivium; Toad the Wet Sprocket; Brett Dennen; Brandy Clark
Katy Perry »Read Full Article
Candy Chang's 'Before I Die...' comes to Milwaukee
There is something about a death that can be focusing. For New Orleans artist Candy Chang, the loss of a dear friend, initially lead to a long period of grief and depression that eventually turned to gratitude and clarity.
She wanted to know what was important, to her and to those in her around her. So the artist, known for her placemaking projects and urban planning ideas, painted the side of an abandoned building with chalkboard paint and stenciled the words, "Before I die I want to..." onto it. »Read Full Blog Post(1)
On Tap Today: Ben Sollee at Shank Hall
Cellist Ben Sollee takes his "Ditch the Van" tour to Shank Hall tonight. Photo provided by Shank Hall. »Read Full Blog Post


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Author Affiliations: Buffalo Neuroimaging Analysis Center (Drs Bermel, Puli, Munschauer, and Bakshi), The Jacobs Neurological Institute (Drs Bermel, Puli, Weinstock-Guttman, Munschauer, and Bakshi), and Department of Neurology (Drs Bermel, Weinstock-Guttman, Munschauer, and Bakshi), School of Medicine and Biomedical Sciences, University at Buffalo, State University of New York, Buffalo; The Mellen Center for Multiple Sclerosis Treatment and Research (Dr Rudick) and Department of Biomedical Engineering (Dr Fisher), Cleveland Clinic Foundation, Cleveland, Ohio; and Physicians Imaging Centers, Buffalo (Drs Munschauer and Bakshi). Dr Bakshi is currently with the Center for Neurological Imaging, Partners Multiple Sclerosis Center, and Departments of Neurology and Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass.
Gray matter magnetic resonance imaging T2 hypointensity, a marker of iron deposition, is associated with clinical impairment and brain atrophy in cross-sectional studies of multiple sclerosis. Treatment with intramuscular interferon beta-1a limits brain atrophy in the second year of treatment.
To test whether T2 hypointensity predicts brain atrophy and whether interferon affects this relationship.
Post hoc analysis.
A multicenter treatment trial conducted at tertiary care comprehensive multiple sclerosis centers.
Patients with multiple sclerosis who took part in a 2-year clinical trial in which they received intramuscular interferon beta-1a (30 μg/wk) or placebo.
Main Outcome Measures
Deep gray matter T2 hypointensity, brain parenchymal fraction (BPF), and total T2, gadolinium-enhancing, and T1 lesion volumes.
T2 hypointensity in various gray matter areas correlated with baseline BPF (r = 0.19-0.39; P = .001-.03). In placebo-treated patients (n = 68), baseline T2 hypointensity predicted the change in BPF in the first year and throughout 2 years (r = 0.26-0.42; P<.001-.03). T2 hypointensity was chosen in regression modeling as the best predictor of BPF change at the 1-year (R2 = 0.23; P = .002) and 2-year (R2 = 0.33; P<.001) time points after accounting for all magnetic resonance imaging variables. In the interferon group (n = 65), no relationship existed between baseline T2 hypointensity and BPF change.
Gray matter T2 hypointensity predicts the progression of brain atrophy in placebo- but not interferon beta-1a–treated patients. This predictive effect is seen as early as the first year. We hypothesize that interferon beta may exert its effect on brain atrophy in part by reducing a cascade of events that involve iron deposition as a mediator of neurotoxicity or as a disease epiphenomenon.
Brain atrophy develops early in multiple sclerosis (MS), affects both gray and white matter, and is thought to represent neurodegeneration.1- 4 Gray matter involvement shown by imaging3- 9 and pathologic7,9 studies may occur by both remote effects of white matter injury (diaschisis) and direct effects of the disease on gray matter.3- 12 The clinical relevance of brain atrophy13,14 is suggested by its better correlation with physical disability13,15,16 and neuropsychologic dysfunction14,17- 20 than conventional magnetic resonance imaging (MRI) lesions. Because disease-modifying treatments have shown only partial effects on atrophy,1,21- 24 there is a need to uncover the mechanisms of atrophy and develop more effective neuroprotective treatments.25
T2 hypointensity in the deep gray matter is thought to represent iron deposition in MS.26- 31 Brain iron accumulation has been detected histologically, and iron metabolism is abnormal in these patients.26,32- 37 Gray matter T2 hypointensity correlates with brain atrophy29 and physical disability28 in cross-sectional studies. We tested 3 hypotheses in this study of patients with relapsing-remitting MS: (1) baseline gray matter T2 hypointensity predicts the rate of whole-brain atrophy throughout 2 years; (2) interferon affects the relationship between T2 hypointensity and atrophy; and (3) conventional MRI can detect progressive T2 hypointensity.
The study design38 and the clinical,39 MRI lesion,40 and whole-brain atrophy1 outcomes of this MS treatment trial of 30 μg/wk of intramuscular interferon beta-1a (Avonex, Biogen Idec, Cambridge, Mass) or placebo have been previously published. Inclusion required clinically definite,41 active38 relapsing-remitting MS. Of 301 patients enrolled in the study, 172 completed 2 years of follow-up. Sixteen had baseline MRI that was incompatible with the present study (corrupt or missing sequences). Images from the remaining 156 patients (n = 78 per group) (Table 1) were analyzed for gray matter T2 hypointensity throughout 2 years. However, images from 23 of those patients could not be analyzed for the 1-year or 2-year conventional MRI data, and the patients were removed from the component of the study in which T2 hypointensity was compared with other MRI variables (Table 2). The smaller final cohort (n = 68 placebo; n = 65 interferon beta-1a) had baseline clinical and MRI characteristics similar to the larger cohort.
Subjects underwent yearly brain 1.5-T conventional spin-echo MRI with a 5-mm interleaved axial series using dual-echo T2-weighted (repetition time = 2000 milliseconds, echo times = 30 and 90 milliseconds) and precontrast and postcontrast T1-weighted (repetition time = 600 milliseconds, echo time = 20 milliseconds) images. Gray matter intensities were measured from T2-weighted (echo time = 90 milliseconds) images on the baseline, 1-year, and 2-year studies using Java Image (version 1.0; Xinapse Systems, Northants, England). A region of interest (ROI) template (Figure 1)28,42 measured mean intensity of each structure normalized to the cerebrospinal fluid.28 The mean intraobserver and interobserver coefficients of variation for measuring ROI T2 intensity (on 10 randomly chosen images) were 0.3% (range, 0.1%-0.6%) and 1.3% (range, 0.1%-2.9%), respectively. Follow-up studies were coregistered43 to their baseline images in 50 randomly chosen subjects (25 from each treatment group) to test the effects of intrasubject differences in head position on the change in T2 intensity. Whole-brain atrophy (brain parenchymal fraction [BPF])1 and T2 hyperintense,40 T1 hypointense,44 and gadolinium-enhancing lesion volumes were obtained.40
Placement and shape of regions of interest (ROIs) used to measure T2 intensities. CSF indicates cerebrospinal fluid; PU, putamen; AT, anterior thalamus; PT, posterior thalamus; GP, globus pallidus; HC, head of caudate; RN, red nucleus; and DT, dentate nucleus. The ROIs 5 mm in diameter were placed in the HC, AT, and PT. The ROIs 2 mm in diameter were placed in the RN. The PU was traced manually, and the GP and DT were traced by an edge-finding seed-growing technique. Care was taken to avoid inclusion of small hyperintensities, such as lesions or perivascular spaces, within the ROIs.
If left-right or anterior-posterior parity was established by a paired-samples t test, intrasubject T2 intensities were collapsed within structures. Between-group and longitudinal differences (paired-samples t test) and Pearson correlations were evaluated. P<.05 was considered statistically significant. A forward stepwise multiple regression analysis evaluated how baseline variables predicted BPF change. P≤.15 was required for a variable to be included, and P<.05 was required for a variable to be retained in the final model.
Left vs right intrasubject baseline-normalized T2 intensities were similar in the caudate (P = .67) and red nucleus (P = .84) and in thalamic ROIs (P = .54) but not in the dentate (P = .04), putamen (P<.001), and globus pallidus (P<.001). The 2-year change in ROI T2 intensity in the placebo group was a mean of +0.20% (range, −1.72% [decrease over time] to +2.06% [increase over time]; P = .06-.96). In the interferon group, the change was a mean of +3.33% (range, +2.27% to +4.37%; P = .21-.49). There were no differences between treatment groups (P = .22-.73). Image coregistration had no effect on the ability to detect ROI T2-intensity change (P = .08-.87). The BPF and T2 intensities were unrelated to age (P = .07-.76).
Baseline T2 hypointensity was associated with baseline whole-brain atrophy (lower BPF; Table 2). In the placebo group, baseline T2 hypointensities, but not MRI lesions and BPF, were associated with the percentage of decrease in BPF during the next 1 year or during the full 2 years (Table 2 and Figure 2). All baseline MRI variables were entered into regression analysis to determine the best predictors of 1-year or 2-year BPF change. In the placebo group, the best MRI predictors of change in BPF in the first year were T2 hypointensity in the thalamus and dentate nucleus (R2 = 0.23; P = .002). In the interferon group, T2 hyperintense and gadolinium-enhancing lesion volumes (R2 = 0.38; P = .006) were the best predictors of change in BPF. In the placebo group, T2 hypointensity in the thalamus was the best baseline predictor of BPF change during 2 years, with T2 hypointensity in the left putamen and red nucleus adding predictive value in the final model (R2 = 0.33; P<.001). In the interferon group, baseline T2 hyperintense lesion volume was the best predictor of BPF change during 2 years, with gadolinium-enhancing lesion volumes also chosen in the final model (R2 = 0.38; P<.001). Thus, the relationship between T2 hypointensity and progressive brain atrophy emerged in the first year. Interferon affected the relationship between early tissue changes and subsequent brain atrophy, beginning in the first year.
The T2-weighted images from 2 patients taking placebo at baseline; T2 hypointensity predicts whole-brain atrophy. Patient A had T2 hypointensity with marked atrophy progression. Patient B had higher baseline T2 intensity with minimal atrophy progression. BPF indicates brain parenchymal fraction.
In patients receiving placebo, baseline T2 hypointensity in the deep gray nuclei predicted the progression of whole-brain atrophy throughout 2 years. T2 hypointensity was selected over the other MRI measures as most strongly predictive of the progression of brain atrophy. These findings suggest a longitudinal relationship between early iron deposition and subsequent tissue loss. However, the strength of the relationship between T2 hypointensity and progressive brain atrophy was only moderate, indicating that other factors were involved.
T2 hypointensity in the deep gray matter most likely represents pathologic iron deposition, as has been confirmed pathologically in normal aging and neurodegenerative disorders.31 Emerging data implicate abnormal iron metabolism as one of the pathophysiologic mechanisms of MS.33,36,37,45 Ferritin levels are elevated in patients with chronic progressive MS.37 Heme oxygenase 1 is up-regulated and is related to increased tissue iron in MS.45 Nonheme iron that acts as a catalyst in oxidation reactions may be abnormally sequestered in deep gray tissue and thus may contribute to secondary tissue damage caused by lipid peroxidation. We speculate that the association between T2 hypointensity and brain atrophy indicates a role for pathologic iron deposition as either a mediator or a disease epiphenomenon.
In patients treated with interferon beta-1a, the relationship between baseline T2 hypointensity and progressive atrophy was disrupted. Moreover, a striking finding was that interferon treatment led to an unmasking of the relationship between all conventional MRI lesion measures at baseline and subsequent whole-brain atrophy. This effect appeared in the first year, indicating that interferon may alter the neurodegenerative process earlier than previously thought.1 We do not understand the reasons for this treatment-associated change in predictive relationships between early MRI findings and subsequent brain atrophy. One explanation may relate to the multifactorial nature of the atrophy process,12,25 in which a drug therapy may have a targeted effect on one aspect of the pathogenic cascade but not another. For example, interferon beta is known to limit the formation of new lesions40 but may not affect the evolution of established lesions.
Interferon beta-1a may affect brain atrophy by modulating systemic inflammatory mediators related to oxidative stress.45 Heme oxygenase 1 expression and mitochondrial iron deposition precipitated by inflammatory cytokines are attenuated by interferon beta.45 However, it may be difficult to extrapolate in vitro data of interferon effects to patients with MS because little if any evidence shows that interferon enters the central nervous system. Another possible mechanism is interferon's ability to stabilize the blood-brain barrier, limiting entry of inflammatory cells and possibly the influx of iron.46 Such limitations of iron accumulation or oxidative stress may help to keep the oxidative load in the brain below a critical threshold level for neurotoxicity. Accordingly, the predisposition of patients with a heavy oxidative burden (T2 hypointensity at baseline) to more severe atrophy would be interrupted early in the disease process by interferon beta-1a. Although we explore the possibility that interferon limits the aspect of brain atrophy that is related to iron deposition in gray matter, such contentions are purely speculative and require further study.
A potentially confounding factor is the reduction of atrophy in the second year in the interferon group, leading to a restricted range of change in BPF and thus a decreased correlation with baseline T2 hypointensity due to a statistical phenomenon independent of any effect of therapy. This effect is unlikely given its appearance during the first year, in which the rate of brain atrophy was unaffected by interferon.1 Other possible causes for the lack of relationship between T2 hypointensity and subsequent brain atrophy in the interferon group include undetermined direct effects of interferon on gray matter or a chance occurrence. Further studies are warranted to confirm and extend our findings.
T2 hypointensity was asymmetric in some ROIs, in agreement with previous studies that showed laterality of MS gray matter involvement.47,48 The asymmetry may relate to normal brain structural variability,49 a nonrandom part of the MS disease process, or an artifact of technique or small sample size.
The thalamus, where T2 hypointensity was most significantly predictive of the progression of atrophy, has been implicated as a site of involvement in MS.7,47,48 Although pathologic iron deposition and neurodegeneration are most likely global processes, it is logical for the thalamus to be linked to whole-brain atrophy owing to its extensive reciprocal cortical and subcortical connections.50
A longitudinal change in T2 intensity of gray matter nuclei was not detected in this study. It is likely that T2 intensity relative to cerebrospinal fluid on standard T2-weighted images is insensitive and unreliable to measure short-term changes in tissue iron. We were limited in this post hoc analysis because the original MRI protocol was not optimized for iron detection. This limitation should be addressed in future studies by iron-sensitive MRI.31 Another limitation was that clinical correlations were not investigated; however, previous work has linked T2 hypointensity of deep gray matter to physical disability and disease course.27,28 Rudick et al51 examined this cohort for effects of corticosteroid treatment and found no effect on the rate of atrophy. The level of disease severity and prevalence of corticosteroid use were similar in both treatment groups; therefore, if the effect is present, it is likely to affect both groups.39
This study links T2 hypointensity and brain atrophy in relapsing-remitting MS. Although we describe what could be a causal relationship between iron deposition and neurodegeneration, iron deposition or some other factor that causes T2 hypointensity may be an epiphenomenon. Future studies should specifically localize and quantify tissue iron and further investigate a possible neurotoxic role.52,53
Correspondence: Rohit Bakshi, MD, Center for Neurological Imaging, Brigham and Women's Hospital, Harvard Medical School, 77 Avenue Louis Pasteur—HIM 730, Boston, MA 02115 (firstname.lastname@example.com).
Accepted for Publication: January 26, 2005.
Author Contributions:Study concept and design: Bermel, Rudick, Weinstock-Guttman, Munschauer, and Bakshi. Acquisition of data: Bermel, Puli, Rudick, Fisher, and Bakshi. Analysis and interpretation of data: Bermel, Rudick, Weinstock-Guttman, Fisher, and Bakshi. Drafting of the manuscript: Bermel and Bakshi. Critical revision of the manuscript for important intellectual content: Bermel, Puli, Rudick, Weinstock-Guttman, Fisher, Munschauer, and Bakshi. Statistical analysis: Bermel and Bakshi. Obtained funding: Bermel and Bakshi. Administrative, technical, and material support: Bermel, Puli, Fisher, Munschauer, and Bakshi. Study supervision: Rudick, Weinstock-Guttman, Munschauer, and Bakshi.
Funding/Support: This study was supported by an Alpha Omega Alpha medical student summer research grant (Dr Bermel), University at Buffalo Summer Research Fellowship (Dr Bermel), and research grants to Dr Bakshi from the National Institutes of Health, Bethesda, Md (NIH-NINDS 1 K23 NS42379-01), National Multiple Sclerosis Society, New York, NY (RG 3258A2/1), and National Science Foundation, Arlington, Va (DBI-0234895).
Previous Presentations: This study was presented in preliminary (abstract) form at the American Academy of Neurology Annual Meeting; April 3, 2003; Honolulu, Hawaii; and as the Oldendorf Award lecture at the American Society of Neuroimaging Annual Meeting; March 7, 2003; New Orleans, La.
Acknowledgment: We are grateful to Mark A. Horsfield, PhD, for assistance with the MRI computer analysis and Anna Davidson, MS, for assistance with the statistical analysis. Jin Kuwata, BS, Jitendra Sharma, MD, Chris Tjoa, BS, and Andrew Fabiano, MD, all provided valuable technical support for the MRI analysis.
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Vagabond Inn Executive SFO Airport
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Historical Traveler Reviews Vagabond Inn Executive SFO Airport Burlingame
This place is the pits
I am in my room now. They gave me a smoking room even though my prepaid confirmation (which I showed them) said clearly non-smoking. The room is so thoroughly disgusting that if I could, I would sleep fully clothed, however, since the AC unit does not work and it is about 90 degrees in my room as I type, that's probably not an option. When I went down to the lobby to tell the young lady about the AC (after turning it on and letting it run for three straight hours), she said, "let me expalin to you...if it is 58 degrees or less and you turn on the AC, it will only blow hot air." She suggested I open a window. Since the window leads right onto the walkway outside my room with only a flimsy screen and since there are children running around and people all hanging out with their doors propped open (obviously the same issue with the AC units), that's not such a good idea. The carpets are soiled horribly and my curtains have a large burn hole in them (Room 310). The room smells bad and overall is filthy. I wouldn't recommend this hotel to ANYBODY under ANY circumstances.
Good value and location
The Vagabond Inn is an excellent choice for those who are looking for a convenient location near SFO Airport and the best value for their $. The rooms are certainly nothing special but they are clean and orderly and have all that you will need for a comfortable stay (except the bed- that was hard as a rock!). The nice thing about the Vagabond is that they offer free breakfast in the lobby each morning and have two computers that you can use free of charge to access the internet. They also have a free shuttle to/from the airport though we did not ride it.
The location is just 2 minutes from highway 101 which can put you in downtown SF or Palo Alto in 15 minutes or so.
Great hospitality!
Thank you for the great hospitality you extended me on my trip over there. I really enjoyed their service very much. The front desk people are very genuine, I feel like at home. They are really helpful even attend to detail-printed us a map so I could navigate our way around there. Really enjoyed the stay and surely will come back on my next trip!!!
I Loved this place!
I got in late one night and missed my car rental reservation, and had to stay overnight til a car was available in the morning. I had never heard of a Vagabond Inn before, I found them on the courtesy-call board and I was pleasantly surprised when I got there. They had free wireless internet, which after a dreadful day traveling, I could connect with my family.
I look forward to another visit to San Fran, and I will be staying there again!
Shuttle never arrived
Our stay at the Vagabond Inn SFO was miserable from the start. We were left waiting outside at the airport on a cold and wet February night for an hour and a half for the hotel shuttle, which never arrived. We called the hotel three times, having to scrounge up change for the pay phone, because there was not a courtesy phone, as we had been told. We waited at the hotel shuttle stop, watching all the other hotels pick up their guests. After 1-1/2 hours of shivering and three calls to the Vagabond, we gave up and called a taxi. The Vagabond didn't want to refund us for the taxi fare, didn't believe it cost us $14, and were not very apologetic. We'll choose other hotels in the future.
airport, cross the street to the center island (there is a sign that says "courtesy shuttle pick up"), and give us a call from the hotel courtesy phone for pick up. We at the Vagabond Inn Hotel pride ourselves in excellent customer service and we look forward to serving you in the near future. Vagabond Inn, "good value, friendly people."
Nice hotel in great location
I've stayed at Vagabond Inn Burlingame in October. I was flying following morning to Hawaii so I took advantage of their Park and Fly package. They took me to and from SFO for free. Breakfast was great and it was free too! Room was nice with fantastic bay view. Staff was very nice.
A great place to stay
I chose the Vagabond Inn because of its location. It is close to the 101 and youcan find it very easily. Check-in was fast, actually, everything was fast, done with a smile by the staff and everybody was friendly. The rooms are quite big for the price, well equipped and had TV, coffee maker, etc etc etc. I really liked it. The breakfast was not too overwhelming but you could have cereals, fruit, make your own waffels, there were danish also......
Very convenient were the computers with high speed access that you could use for free in the lobby!!
Great Place, Great Price, Close to Hwy and Airport
Chose this place for price but was pleasantly suprised with the room. Newly remodeled and currently redoing the lobby and office. Close to airport, restaurants, and Hwy 101. Easy to get in and out of to head to San Francisco. The free breakfast is not going to fill you up. If you want a full meal, pay the extra and go to La Quinta in San Bruno. More costly but you won't be spending on breakfast. I would stay at the Vagabond again. Very friendly staff, courteous.
TripAdvisor Reviews Vagabond Inn Executive SFO Airport Burlingame
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Golden Gate Bridge
... the bridge and the clouds parted just for our photos!
After a quick stop there, we climbed the stairs to a little platform that was level with the bridge.
There were some cute little hummingbirds flitting around the flowers on the way up and some cool little tunnels and things too. It was pretty nice.
From the top it was a pretty nice view of the bridge, but there were so many people on the tiny platform that it was hard to get good photos anyway. The ones ...
San Francisco living - Days 89 - 92
... to be cooked. The half and half veggie and sausage pizza was just the trick! It had been a relaxed, real-life sort of day, which we'd really enjoyed having already got a good feel for San Fran city and its main sites. Heading back to our place in the Castro, we almost felt like residents! Day 92 - Cycling over the Golden Gate Bridge! Everyone had told us we should hire bikes and cycle over the bridge to Sausilito whilst we were in SF. So, feeling fresh and hangover-free we ...
Chicago, IL: Day 1
... and dad were enjoying themselves a lot thanks to the drinks! We ended up only be able to eat a small amount of pizza, despite earlier laughing at the suggestion of the small pan sizes; we couldn't believe an 'individual' size pan (about 15 cm diameter ?) would actually fill someone up. Mum and I were only able to eat 1 slice (that we both couldn't even finish), Ryan had 2 (shock horror Ryan only eating TWO!) and dad managed to polish off 3, just. Needless to say we took a lot of pizza ...
Sunday in San Francisco
... Eugenie (and her hat) Beyonc�, Katy Perry, Justin Bieber, Nicki Minaj, Hillary and Bill Clinton, Oprah Winfrey, Nancy Pelosi, Michael Jackson, Adele, Barbra Streisand, Lady Gaga, Elvis and the San Francisco Giants. Finished off with some outstanding singing , dancing Christmas trees. The costumes were great but the hair-OMG- there is big hair and then there is Beach Blanket Babylon big hair!
Dinner at The Stinking Rose
Not quite what you expect but this ...
Day Twenty-One: Typical Tourist
... of place that you would definitely feel trapped in and miserable if you had to spend time there as an inmate. But then I guess any prison would be like that. There was a free audio tour included in my ticket price, so after I'd walked around a little I ventured into the main cell building and learnt all about Alcatraz from prison guards and previous inmates. The tour was very well done, and for anyone who enjoys history and ...


text:
3 posts tagged with running by never.was.and.never.will.be..
Displaying 1 through 3 of 3.
training indoors for a hilly marathon - help!
I just ran 4.0 miles at a 4% incline on a treadmill. How much elevation gain does that equal, in feet? [more inside]
help me stop feeling nauseous after running
I always feel nauseous towards the end and after a long run (~8+ miles). Will drinking gatorade or another sports drink during the run help with that? If not, what will? [more inside]
How do runners pass the time?
What are some games that 2 people can play while running long distances to pass the time? [more inside]
Page: 1


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Snowboarding Forum - Snowboard Enthusiast Forums (http://www.snowboardingforum.com/forum.php)
- Welcome New Riders And New Members (http://www.snowboardingforum.com/welcome-new-riders-new-members/)
- - snowboard.com transplant here (http://www.snowboardingforum.com/welcome-new-riders-new-members/15405-snowboard-com-transplant-here.html)
snowboard.com transplant here
What up everyone? Well that site is kaput me thinks?
I heard that a bunch of members had migrated over here so I thought I would give it a go.
My name is matt and I was born and raised in arizona. Still live in az and I reside in prescott valley. I do a ton of out of state trips every year and the places I go are mammoth, snowbird/brighton, brian head, crystal, alpental, and stevens. I also hit sunrise and snowbowl when i can't find other people to head out of state.
Im a freerider but hit the park on occasion
my setups?
jamie lynn 157w with burton cartels
burton fish 160 with burton cartels
my boots are burton serows
1 Attachment(s)
Hey, good to see you here. :)
Lot's of refugees will be found here.
hey matt, i happened to wander over here from sb.com also. Its a shame it went so downhill, but I guess theres always something else you can find to waste time on. Unlike you americans, I come from Toronto to the north of the US of A
welcome and make yourself at home. lots of sb.com refugees around here. you will find that this place is a hell of a lot more stable than TOS ('the other site' as its known on this forum)
this place is what TOS wishes it could be!
what happened too that site, anyways? it looks healthy to me- i was thinking about going over there to post =/
Hey Matt, Tucson kid here. Bought a season pass up to Sunrise, maybe see you there sometime?
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text:
Loveland, COUSA
March 13, 2013
No answer yet
Looking for a great group to learn and play!
Help support your Meetup
WARNING: This is not your traditional Golf League! Most, but not all of us are just beginners in golf, mothers who admittedly want to get away from their families come Sunday afternoon, have no shame in having at least three cocktails on the course and are thrilled about golfing solely on the premises of meeting new sassy women and acquiring a tan.
What is SWING?
SWING is a traveling cocktail league for women. We bypass competition & focus on building relationships while enjoying the game in a relaxed atmosphere. We play 9 holes 3-4 times a month, you are welcome to join any event that sparks your interest! There is no attendance obligation. All levels are welcome.
Where is SWING?
Currently we are playing in Northern Colorado, Boulder County, Denver and various California markets.
We will expand upon demand. If you are interested in starting a SWING chapter in your area please contact Jennifer Jennings at firstname.lastname@example.com
How did SWING begin?
It was the summer of 2010 and Jennifer Jennings (founder) was enjoying a round of golf with her husband, well, watching him enjoy his round would be more accurate. The stress of trying to learn from your husband on top of missing the ball every third swing was far from a pleasant afternoon on the course. Day dreaming of a better way, the idea of playing with women that had the desire to learn in a relaxed atmosphere where cocktails come in twos and making par means you got to the green! As she researched what GOLF meant she found it stood for Gentlemen Only Ladies Forbidden. Of course that isn't true, however it did inspire her to create her own acronym and by doing so a new culture was born.
Golf is traditionally viewed as a male dominated past time where business deals are done and careers are advanced. SWING brings those advantages to women in a non-threatening social atmosphere. SWING is a lifestyle, where women can be empowered on the golf course and in business while having a great time doing what they want, where they want.
Annual Membership Levels
Please visit our website for current member pricing. http://www.swinggolfclubs.net/membership
DROP-IN RATE IS $20 FOR NON-MEMBERS (in addition to green fee)
You have to RSVP on meetup.com but do not have to have your foursome formed. Just show up and be ready to have some fun!! Cancellations within 24hrs and no shows are responsible for paying their green fees.
For additional information please visit www.swinggolfclubs.net
I hope to see you all soon! CHEERS
30% OFF Membership
Buy 1 martini, get your 2nd martini HALF OFF!
50% OFF any bottle of wine with ANY food purchase! WOW!
20% OFF all services (only valid with select stylist)
1,214 Professionals
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1,133 Longmont Socials
Meetup members, Log in
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Museum Education Program Assistant
General Information
Date Prepared:
Henry Sheldon Museum
1 Park St, Middlebury
Primary Purpose
1. Learn about materials and information used in Henry Sheldon Museum Education Programs.
2. Work with Museum Educator to present educational programs primarily for K-8 students both at the Museum and in local elementary schools.
3. Help prepare mateials for school programs, special events and exhibits.
4. Work at special events, as student's time allows.
1. Outgoing personality 2. Works well with people all ages 3. Computer literate 4. Able to work independently 5. Good communication skills 6. Some knowledge of American Colonial History very helpful 7. High interest in continuing to work in an educational setting


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Sean Astin
Actor + Director + Producer
Born Feb 25, 1971
Sean Astin is an American film actor, director, voice artist, and producer best known for his film roles as Samwise Gamgee in the Lord of the Rings trilogy, Mikey Walsh in The Goonies, and the title character of Rudy. In television, he appeared as Lynn… Read More
View newly released photos of Sean Astin.
News + Updates
Browse recent news and stories about Sean Astin.
On The Road For HillaryHuffington Post - 8 days ago
Sean Astin Says Mother Patty Duke Suffered 'terribly' Before DeathLATimes - Mar 31, 2016
'my All American' Gets Extra Points For Heartstring TugsHuffington Post - Nov 14, 2015
"Woodlawn" Scores BigHuffington Post - Oct 17, 2015
Learn about the memorable moments in the evolution of Sean Astin.
1971 Birth Sean Astin was born Sean Patrick Duke on February 25, 1971 in Santa Monica, California, the son of actress Patty Duke. … Read More
1972 1 Year Old On August 5, 1972, Patty Duke married actor John Astin, after having been in a relationship with him for two years. … Read More
1973 2 Years Old In 1973, Duke gave birth to Astin's half-brother Mackenzie Astin, who also became an actor.
1981 10 Years Old Astin's first acting role was in a 1981 television movie titled Please Don't Hit Me, Mom, in which he played a child with an abusive mother (portrayed by his real-life mother Patty Duke). … Read More
1985 14 Years Old Patty Duke and John Astin divorced in 1985. Duke married Mike Pearce in 1986, and they adopted a son, Kevin, in 1989. … Read More
1994 23 Years Old In 1994, Astin directed and co-produced (with his wife, Christine Astin) the short film Kangaroo Court, which received an Academy Award nomination for Best Live Action Short Film. … Read More
2001 30 Years Old In the early 2000s, Astin experienced a career breakthrough with his role as Samwise Gamgee in Peter Jackson's The Lord of the Rings film trilogy, released in 2001, 2002, and 2003. … Read More
2003 32 Years Old … He directed a 2003 episode of the TV series Angel, titled "Soulless". … Read More
2004 33 Years Old During the 2004 United States presidential election, Astin backed Senator John Kerry and participated in Kerry's campaign rally in Portland, Oregon, as the opening speaker.
2008 37 Years Old In the 2008 presidential election, Astin lent his support to Senator Hillary Clinton and made multiple campaign appearances on her behalf, including joining Clinton's daughter, Chelsea Clinton, at some stops. … Read More
2010 39 Years Old In 2010, he joined the Stella Adler Los Angeles Theatre Collective acting company. … Read More
2012 41 Years Old In March 2012, Astin played a cosmetic surgeon named Takin Mastuhmik in a fake movie trailer entitled Boobathon which appeared on Funny or Die.
2014 43 Years Old 1 More Event
In March 2014, Astin played a soldier in Boys of Abu Ghraib, a military thriller inspired by the events that made worldwide news in 2004.
Original Authors of this text are noted on http://en.wikipedia.org/wiki/Sean_Astin.
Text is made available under the Creative Commons Attribution-ShareAlike License.
Text is made available under the Creative Commons Attribution-ShareAlike License.


text:
Danica Patrick on CrossFit and Yoga With Her Dogs
"I'm one of those people who actually likes to work out."By Danica Patrick as told to Susan Rinkunas
"I'm one of those people who actually likes to work out."By Danica Patrick as told to Susan Rinkunas
Driving lessons with championship winner Julia Landauer.By Shiona Turini
A grand jury decided on Wednesday.By Jessica Roy
It will play at a NASCAR event 72 times this weekend.By Dan Amira
Ironic, but not funny.By Adam Martin
On the day before the Daytona 500.By Andre Tartar and Caroline Bankoff
This is getting ridiculous.By Dan Amira
Insiders describe it as a "red state 'Mad Men'"By Claude Brodesser-Akner
The hypothesis: Mario is spinning out of control. The proof: zilch.By Daniel Maurer
Paula Zahn's friends say she wanted to stay in the Fifth Avenue apartment she shares with soon-to-be ex-husband Richard Cohen for the sake of their kids, but he made it too difficult. Lou Dobbs's daughter Hillary won the Open Jumper Class (and $7,500) at the Hampton Classic Horse Show. (Soon-to-be-mom Kelly Klein also rode there.) Heather Mills has racked up a number of parking tickets in her Bentley convertible in East Hampton. NYU's school newspaper went out of its way to point out that people use the campus library to commit suicide and hook up on Craigslist. Larry David doesn't like fund-raisers on yachts in Martha's Vineyard. Courtney Love is blaming ex-boyfriend Steve Coogan for Owen Wilson's attempted suicide, and now Coogan is worried about his career prospects. The New York Times has a clear anti-Yankees bias, "Page Six" says.


text:
Tap Pet Hotel Answers for iPhone - iPadHome / iPhone - iPad /
Game Questions & Answers (Q&A) service lets you ask questions about video games for game consoles or PC games. So ask your Tap Pet Hotel question for iPhone - iPad and get answers from real gamers or answer questions and share your insights and experience with the rest of the gaming community.
- Developer: Pocket Gems, Inc.
- Publisher: Pocket Gems, Inc.
- Genre: Role-Playing
- Release: Apr 21, 2011
- ESRB: Not Set
Question & Answers
Improve social rating
How do you improve social rating in the hotel ratings? i collect coins from neighbors but still only have only 1/2 a star on that scale
Answer from: kayluhh
You have to improve your social name. when you collect coins, it gives you xp in the social. as of right now, i am named a hotel manager and only have one star. its obviously a super long process to improve it.
Answer from: howlingwolf
That's not true, i'm also hotel manager and i have 2 and a half star. you just have to visit a lot of people. here's a tip: every time you visit someone tap just 1 room, and not three or two. the social rating goes really slow so you have to be patience. good luck ;)!
Answer from: Jvkitkat
I'm manager as well and i have 5 stars. i visit lots of people everyday and both upgrade coins and pop balloons (easy way to get coins and the balloon popper achievements).
Answer from: Courtney
I am senior in my social rating and i only have one star. and i also pop all balloons when visiting my neighbors and it it's going up any.
Answer from: Char
I really don't think visiting neighbours has anything to do with the social star rating... i am on 'owner' and visit dozens of neighbours a day and my star rating for social is only 1.5 star... i think it's to do with your social rooms and how many times you get the top prize!
Answer from: Ynot88
I have 5 stars build your rank through connectots, hotel size, social (by clicking on visit button and tapping neigbours coins), if you build pet rooms make sure you build also kids to make kid friendly ranking, party rooms, decorations, fun rooms. lots of balloons both regular and hearts im at 10000 level now on balloons. in the guest book you'll see completion of hearts, party room, and food. yes, food as in bakery etc. it also depends on how fast you want to build up - more coins and treats. not worth completing task using except maybe 1 treat for food
Answer from: Summer
I think as your hotel grows your social name has to too to keep lots of stars just like you have to build more connectors. it def has something to do with neighbors because my stars are telling me to get out more to improve my ranking. most of my other stuff is already high
Tap Pet Hotel - Gameplay Review
- Aug 27, 2014, Views: 225
- The Journey: Bob's Story, (PC)
- Call Of Duty: Infinite Warfare, (PS4)
- Titanfall 2, (XONE)
- Beyblade Burst, (3DS)
- Dragon Ball: Xenoverse 2, (PS4)
- Mario Party: Star Rush, (3DS)
- Runbow, (3DS)
- Gears Of War 4, (XONE)
- SouzaSim: Moped Edition, (AND)
- Yakin, (iOS)
- Vulture Island, (iOS)
- Mystic Messenger, (iOS)
- Pixel Cup Soccer, (iOS)
- Slots Free Casino House Of Fun - Play Vegas Jackpot Slot Machines, (iOS)
- Fired Up, (iOS)
- Wordalot: Picture Crossword, (iOS)
- Riff Racer: Race Your Music, (iOS)
- Hologram Luigi Runner Bros 3D Simulator, (iOS)
- Ember, (iOS)
- Solitaire., (iOS)
- Roblox, (iOS)


text:
National Renewable Energy Laboratory (NREL) Education
Learn more about Teaching Climate Literacy and Energy Awareness»
See how this Video supports the Next Generation Science Standards»
High School: 6 Disciplinary Core Ideas
Grade Level
Regional Focus
Energy Literacy
4.1 Humans transfer and transform energy.
5.4 Economic factors.
Notes From Our Reviewers
The CLEAN collection is hand-picked and rigorously reviewed for scientific accuracy and classroom effectiveness.
Read what our review team had to say about this resource below or learn more about
how CLEAN reviews teaching materials
Teaching Tips | Science | Pedagogy |
Technical Details
Teaching Tips
- A professionally-produced overview of wind energy and related research at the NREL National Wind Technology Center near Boulder, Colorado.
- Link for video includes a printable transcript of the video for students to follow.
- Students could create a flow chart that illustrates how wind energy is converted into useable energy.
- Suggested that teachers discuss local and regional wind patterns, why wind generators are located where they are.
About the Science
- Presents the science, technological challenges, and the social and funding issues involved with developing wind technology.
- Includes some basics on wind energy, wind dynamics, and how wind turbines work.
- Passed initial science review - expert science review pending.
Next Generation Science Standards See how this Video supports:
High School
Disciplinary Core Ideas: 6
HS-PS3.B1:Conservation of energy means that the total change of energy in any system is always equal to the total energy transferred into or out of the system.
HS-PS3.B2:Energy cannot be created or destroyed, but it can be transported from one place to another and transferred between systems
HS-PS3.B4:The availability of energy limits what can occur in any system.
HS-PS3.D1:Although energy cannot be destroyed, it can be converted to less useful forms—for example, to thermal energy in the surrounding environment.
HS-ESS3.A1:Resource availability has guided the development of human society.
HS-ESS3.A2:All forms of energy production and other resource extraction have associated economic, social, environmental, and geopolitical costs and risks as well as benefits. New technologies and social regulations can change the balance of these factors.


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Anesthesiologist (pain control)
16 years of experience
Accepting new patients
16 years of experience
Accepting new patients
351 Consort Dr
Ballwin, MO 63011 Phone number & directions
351 Consort Dr
Ballwin, MO 63011 Phone number & directions
License & Identifications
A medical license is required for a doctor to practice medicine in a particular state. Requirements vary by state but most require, at a minimum, post-graduate training in the doctor's specific specialty. An NPI number is a national identifier unique to an individual health care provider and is managed by the Center for Medicare & Medicaid Services (CMS).
Learn more about Dr. Jeffrey Alexander:
View the full profile to get information on:
- Qualifications
- What's important to you
View full profile
Patient Reviews
Have you visited Dr. Alexander? Share your experience.
Write a Review
Write a Review
Specialties & Research
Dr. Jeffrey Alexander, DO is board certified in Anesthesiology.
Education & Awards
Dr. Alexander graduated from A.T. Still University - Kirksville.
Dr. Alexander has 7 hospital affiliations:
- St Anthonys Medical Center
- St. John's Mercy Medical Center
Home > Find an Anesthesiologist > MO > Ballwin Anesthesiologists > Dr. Jeffrey Alexander, DO
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- Additional Information
- Dr. Jeffrey Alexander DO is a male Anesthesiologist, has 16 years of experience and practices in Anesthesiology.
- Where does Dr. Jeffrey Alexander practice?
- Dr. Jeffrey Alexander has 2 office locations.
Dr. Jeffrey Alexander practices Anesthesiology near Ballwin, MO.
Additional practice locations include: Chesterfield, MO.
See Ballwin Anesthesiologists.


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Best Customer Service Training Company
Every day that you run a customer call center or other business, there's an impact on profits – for better or worse. Your reps and staff are the front door to your organization, and to your customers, they are your company, and even your product or service. Do they have the training to be the best they can be?
Whether you're looking to enhance a healthy culture or drive cultural change, Bonfire Training helps align your frontline and management teams for a far-reaching impact within your organization.
Don't Leave Your Customer Service Training to Chance
We are a customer service training company and much more. Simply put, we teach your customer service reps to communicate with empathy, knowledge, and professionalism and we teach your leaders and managers to get the best possible performance from their staff.
The best reps do a lot more than just answer the phone. They care for your customer. They help them understand your product, and maximize its benefits. They can even help upsell them on your latest new products. In the battle to build loyal customers, they can be the difference between winning or losing.
We Are Customer Service Training Providers
We know how to strike a balance between communication management and interpersonal relationships in our training sessions. Together, we'll give your organization the spark it needs to reenergize your frontline team and internal staff, and create happy customers.
When you work with Bonfire training, you won't have to settle for a "cookie cutter" program filled with vague advice. Our staff takes its time to observe your customer service strengths and weaknesses, and analyze your environment to create a customized program that addresses your particular challenges and is delivered with examples that are specific to your company.
We get to the bottom of your biggest service challenges, so you can develop the service strategies that address the root of the problem. Then, we develop the customized service training that gives your people the skills they need to succeed, every day.
Our trainings are custom designed to address the real world scenarios your customer service reps face. When your people are trained by Bonfire, you won't have to worry about long lead times for implementation. By the time they leave our training, they'll be ready with the information, processes, and confidence they need to meet any customer challenge.
Your Profits Are on the Line
We are your go-to customer service training supplier. Contact us today for more information about how we can help you – and your bottom line.
Bring a Bonfire team member to your workplace for a completely customized training program.Learn More
Online training with Bonfire webinars offers easy, affordable ways to ignite new customer service skills.Learn More
Management teams across all industries value our fresh take on communications training.Learn More
Amid a continuous blizzard of fair-to-middling "customer service reports," every few years Americ...Read More
We received a question from a new supervisor in a government emergency management position after...Read More
Many people unfamiliar with the world of customer service leadership are quick to say that their...Read More
Back in October, Lisa Rike gave some great information about how to deal with difficult customers...Read More
F. Scott Fitzgerald described it best when he wrote, "Life starts al...Read More
"Hello? I'd like to order a fruitcake – the one with the pecans." "What's that? You're sold out?...Read More


text:
Crystal Ball to honor Archie, Olivia Manning
Archie and Olivia Manning will be honored as the 2013 Stars of the year by the Community Foundation of Northwest Mississippi at Crystal Ball XIII. The gala is scheduled for Saturday, Jan. 19, 2013, at The Arena at Southaven.
Archie, a native of Drew in Northwest Mississippi, has been voted Mississippi's Greatest All-Time Athlete. He had an All American football career with Ole Miss and then the New Orleans Saints, where he was named the conference's Most Valuable Player. He has been very active in charitable causes including Boy Scouts, Special Olympics, and Salvation Army.
Latest News
'Highway killer' convicted in retrial A man who went on...
Fifteen Years Later One Tunican's special...
A Flag Folding and Bell Ceremony for 9/11 Tuesday, September 11,...
TA presents Homecoming Court Tunica Academy's Homecoming...
Revival stirs churches to act as one in Christ Jesus By turns smiling and...
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Slow (band)
|Vancouver, British Columbia, Canada
|punk rock
|Years active
|Zulu Records
|Associated acts
|Chuck & the F***s, Copyright, Tankhog
|Past members
|Thomas Anselmi
Christian Thorvaldson
Stephen Hamm
Terry Russell
Ziggy Sigmund
Slow is a Canadian punk rock band that started in the mid-1980s. Based in Vancouver, British Columbia, the band consisted of vocalist Thomas Anselmi, guitarists Christian Thorvaldson and Ziggy Sigmund, bassist Stephen Hamm and drummer Terry Russell.[1]
Hamm and Russell had previously been in a West Point Grey punk band called Chuck & the Fucks, playing an infamous concert at Queen Mary Elementary in the spring of 1980 where many of the teachers forced the children to leave.
They recorded and released their debut single, "I Broke the Circle", in 1985 on Zulu Records, and followed up with the EP Against the Glass in 1986.[1] The band's style was also cited as an influence on the nascent grunge rock movement in the nearby Seattle music scene, especially on its adoption of clothing styles such as flannel shirts, ripped jeans and heavy boots.[1]
Expo 86 show[edit]
Slow are most famous for a controversial incident which both marred the Expo 86 festivities and effectively ended the band's career, when the band were invited to play at the event's Festival of Independent Recording Artists. According to Anselmi, the band's original idea was to simply appear on stage naked, run through the crowd to a boat on False Creek and then simply disappear without playing a note;[1] however, the band ultimately chose to put on a more typical performance.[1] Typical, that is, for Slow – the show included Anselmi pitching two two-by-fours into the front rows' empty seats at the side of the stage,[1] and both Anselmi and Hamm followed through on the original idea to strip. Anselmi stripped off his shirt and jeans and performed in a pair of boxers, occasionally "poking through" the front as he adjusted his underwear; at the end of the set, Hamm dropped his shorts to his knees and, with arms raised in triumph, said goodbye to the audience while naked from the waist down.[1] In response Expo officials cut the power to the pavilion, ending the entire event.[1]
The band were detained by the Vancouver police, who considered charging them with indecent exposure. Citing security concerns, Expo officials cancelled the evening's headlining concert, Poisoned featuring Art Bergmann; subsequently, the entire week-long festival was also cancelled.[2]
Some of the fans in attendance got onstage and many in the audience refused to leave the venue. A chant of "BCTV" started in the crowd and a large group marched to the location of BCTV's onsite studios. The group gathered outside the studio windows, where they protested the concert's cancellation so loudly and persistently with chants of "Expo sucks" that the station had to pull its 11:00 pm newscast. Instead, BCTV started its late night movie early; the movie was Rock 'n Roll High School featuring the Ramones.[1]
The band subsequently embarked on a cross-Canada tour, although the negative publicity they received as a result of the Expo show led them to split up by the time they returned to Vancouver.[1] Anselmi and Thorvaldson continued to collaborate under the band names Mo and Christian Thorvaldson's Freeze-Dried Dog before settling on the new band name © in 1988,[3] while Hamm and Russell launched Tankhog.[1]
In a 1996 reader poll conducted by Chart, Against the Glass was named the 17th best Canadian album of all time, and their single "Have Not Been the Same" ranked as the 10th greatest Canadian song. Have Not Been the Same: The Can-Rock Renaissance 1985-1995, a 2001 book by music journalists Michael Barclay, Ian Jack and Jason Schneider about the rise of alternative rock in Canada in the late 1980s and early 1990s, also took its title from the latter song.
- ^ a b c d e f g h i j k Michael Barclay, Ian A.D. Jack and Jason Schneider, Have Not Been the Same: The Can-Rock Renaissance 1985-1995. ECW Press. ISBN 978-1-55022-992-9.
- ^ "Slow biography", Jam! Canadian Pop Encyclopedia. Retrieved on 2009-03-10.
- ^ "Ex-Slow duo puts together band with a wicked sound". Vancouver Sun, October 14, 1988.


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This Property is Off-Market
600 Acres in Osage County, MissouriRolla , MO 65035 | Osage County, MO
|Listing Status:
|Off Market
|Listing Type:
|600 acres
|Property Type(s):
|Last Updated:
|Cropland Acres:
|Contact broker
|Property ID:
Description600 acres Osage Co., MO with an amazing view of the beautiful Gasconade River. With almost a mile of river frontage you have your own access and a great view from the bluffs. This farm has the versatility to be every sportsman's dream. You can go straight from Turkey hunting those crisp spring mornings to Smallmouth Bass fishing in the afternoons and Deer to Crappie in the fall. I'm not sure it can get any better than that. With 55 acres of tillable bottom ground (20 acres currently in CRP) and 150 acres of open pasture for potential income and forage for the wildlife. Also, with numerous food plot sites, pinch points and funnels galore, and is secluded to help keep hunting pressure to a minimum, this farm has the potential to produce big mature bucks. If you need more recreation you have multiple lake sites to choose from. This farm has something to offer every outdoor enthusiast; hunting, fishing, camping, swimming, and even some farming. With the old farm house ready to be renovated into a lodge and numerous buildings make the farm an exceptional value. Don't miss out; farms like this don't come up for sale very often.
Map of 600 Acres in Osage County, Missouri
Information Provided By
This Property is Off-Market. Last modified on 1/7/2016
D.W. Hindman
Living the Dream, Inc,