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Mighty Mesenchymal
Researchers band together to harness the power of adult stem cells to fight disease
The rattling news came five years ago: It was multiple sclerosis (MS) that was steadily leeching the strength from gym owner and personal trainer Bill White. Pre-disease, the fitness enthusiast had weight-lifted his way to a brawny 233 pounds, but in his early 40s, the frustrating clumsiness, fatigue and weakness became gradually more disabling and harder to ignore.
"I tried to keep going," says White, who also owned a flooring company and fought with all his might to keep MS from hijacking his chock-full life. Still, he says, "It finally hit me—I couldn't keep up with it all anymore."
The autoimmune disease, White was warned, would lead to deterioration of muscle control, balance and vision, as his immune system attacked his central nervous system, damaging his nerve cells and their protective myelin sheath. Doctors prescribed standard MS medications glatiramer acetate (Copaxone) and then interferon beta-1a (Avonex)-drugs that slow the disease but, unfortunately, are powerless to reverse the nervous-system damage caused by the disease process. However, White says, the meds caused intolerable side effects: His appetite all but disappeared, and he felt he was wasting away.
After two years and 53 pounds lost, the former standout football player and wrestler considered "stopping all the shots, and going all-natural." Acknowledging that protein shakes and fruits and vegetables alone would be no match for his condition, though, White and his wife toyed with going abroad for much-hyped unconventional treatments they read about online, but the money wasn't there.
Then, White found hope close to his suburban Cleveland home. His neurologist Jeffrey Cohen, MD, professor of medicine at the Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and director of the Mellen Center's Experimental Therapeutics Program at Cleveland Clinic, was gearing up for a new multiple sclerosis study. He wasn't researching a new drug, but, rather, a way to empower the body's own mesenchymal stem cells (MSCs) to treat the disease.
The study, now in full-swing, joins lead investigator Cohen with other School of Medicine faculty members who practice at clinical affiliates University Hospitals (UH) Case Medical Center and Cleveland Clinic. They are testing the safety of MSCs in multiple sclerosis patients like White—taking the first step toward harnessing the body's inner abilities to fight a disease that affects more than 2.5 million people around the world.
Bill White, diagnosed five years ago with MS, says he feels less tired and is able to walk better since receiving an MSC transplant as part of the clinical trial.
Sending a Signal
Mesenchymal stem cells are found in several tissues, including adult bone marrow, and can differentiate into bone, tendon and other connective tissues. Much mystery still shrouds the precise mechanics of MSCs, but researchers have identified three characteristics of these particular stem cells that make them especially useful tools.
First, when administered intravenously, they are able to spot areas of inflammation and damage and wend their way through the bloodstream to where they are needed. Second, they have the ability to regulate the immune system to decrease an overactive inflammatory response, while blocking formation of scar tissue. And, third, they can regenerate tissue-not by turning into tissue themselves as some stem cells are known to do, but by providing healing instructions to other repair mechanisms at the injury site.
"MSCs' response to their environment is remarkable," says Stanton Gerson, MD, the Asa & Patricia Shiverick and Jane Shiverick (Tripp) Professor of Hematological Oncology at the School of Medicine, director of the school's National Center for Regenerative Medicine and Case Comprehensive Cancer Center, and director of UH Case Medical Center's Seidman Cancer Center. "When they find themselves in an inflamed place, they shut down inflammation. If they find themselves in a wounded place, they help it heal. If they find themselves in a place overrun by bacteria, they fight off the infection." The cells' adaptability, Gerson says, could someday translate into an expansive clinical role for the cells. (See "A Range of Research")
Renowned researcher Arnold Caplan, PhD, a professor of biology at Case Western Reserve, suggests MSC could more aptly stand for "medicinal signaling cell." He calls them the body's "drugstore" because once they reach the place they're needed, they help the body heal itself as it should naturally do.
A New Spin on Stem Cells
MSCs have been hailed over the years as a method-in-the-making to grow replacement parts for damaged organs. While this line of study is slowly progressing, the Cohen-led clinical trial is looking at the cells in a very different way: They are taking an MS patients' mesenchymal stem cells from their own bone marrow, isolating the cells in a laboratory to boost their numbers, and returning them intravenously to the patients to see if they can halt the progression of multiple sclerosis or even reverse the disease by repairing harmed tissue. (See "Multi-institutional Effort")
White is among the 24 patients to be recruited for the study-all with relapsing or progressively worsening MS and with moderate to severe disability from the disease.
As a Phase I trial, the study is designed to focus on safety. But the tests will also shed light on functional improvement, emphasizes Robert Miller, PhD, professor of neurosciences, vice president for research at the university and the researcher whose basic science studies inspired the clinical trial. Preliminary findings are expected in 2012, with updates to follow.
For his part, White says he felt improvement within weeks of receiving the MSC transplant. He says he's less tired than before the study, and he can lift his left leg under its own power, where he used to use his arm to assist. "Within just two months," he says, "three people noticed I was walking better. And people are saying 'you look better.' "
From Clues to Clinics
It has taken decades of research to bring scientists to today's understanding of MSCs and their potential in medicine. Since the late 1980s, Case Western Reserve's Caplan has been front-and-center in the study of MSCs as building blocks for engineered tissues and organs. And Caplan-who has been referred to as the "American Father of MSCs" by stem cell pioneer Hillard Lazarus, MD-developed the technique for growing MSCs isolated from the bone marrow into large numbers of cells.
Caplan started working with Miller in 2003. Their basic-science studies showed how human MSCs can promote healing and protect against a destructive autoimmune response. Caplan recalls the results: "The mice were cured of their MS-like disease. Not only did the MSCs stop the immune attack that led to myelin damage, but the animals remyelinated."
What was more, the animals showed no signs of rejecting the human cells. MSCs seem to be "immunologically privileged," says Lazarus, professor of medicine at the school, director of the Novel Cell Therapy Program at UH Seidman Cancer Center, and the stem-cell expert who initiated the first U.S. clinical trials with MSCs in 1991. He adds this so-called immunity also has been shown in person-to-person transplantation. "MSCs can set up shop in a different host without being recognized and knocked out." This characteristic broadens the cells' potential usefulness to include allogeneic transplant, in which patients receive stem cells from a donor rather than their own cells.
Based on these heartening results from preclinical studies, Caplan and Miller encouraged multiple sclerosis expert Cohen to develop the current clinical trial protocol, which won a $2.75 million, four-year grant from the U.S. Department of Defense and a $1 million grant from the NIH.
This kind of multi-institutional collaboration, where investigators combine individual expertise to see research through from the basic biological underpinnings to preclinical testing to intricate clinical trials, Caplan says, is a hallmark of Cleveland-area research. It's this collegial atmosphere that sets the city apart from other medical research hubs, he says. And it's the kind of attitude that attracted him to the area more than 40 years ago and that has kept him moored throughout the decades.
"World-class experts can walk across campus and talk to each other," he says. "It's great, the way top experts in different subspecialties get together here and play ball."
Progress and Predictions
While the multiple sclerosis clinical trial is still in its early innings, Cohen says no side effects or complications have been seen from the safety data so far. Given positive results from this trial once it is complete and from follow-up trials, the therapy could be widely available to patients with MS within seven to 10 years, by the lead investigator's estimate.
White, for one, won't have to wait that long. He says the procedure—in concert with his dogged determination not to fall victim to the call of his wheelchair, even when walking gets hard—has already done for him what standard medications could not.
"I'm starting to get back what MS took from me for five years. I see some of my stamina coming back, and my hope is that I'll get 100 percent better," he says.
DISCLOSURE: Arnold Caplan, PhD, founded the company Osiris Therapeutics, Inc (OTI), which is commercializing mesenchymal stem cells. Osiris sends royalties to Case Western Reserve University for certain applications of mesenchymal stem cells, and these royalties are shared with Caplan, Stanton Gerson, MD, and other Case Western Reserve University inventors. Gerson is a director of research centers at both University Hospitals Case Medical Center and Case Western Reserve University, and he has an ownership interest in Osiris.


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At the very least, Roderick King said, he thought he was in for a beating.
It was after 2 a.m. on March 31, 2013, King recalled during a preliminary hearing Tuesday, and he was in Center City, handcuffed in the rear of a Philadelphia police SUV.
The officer, apparently incensed because one of King's friends had accused him of making an illegal turn, put King in the SUV and drove him to a dark alley in North Philadelphia.
"It was just him and me," said King. "I was very scared."
Though King said the officer never gave his name, he turned out to be Kevin Corcoran, 33, a nine-year veteran of the force with a history of complaints for using excessive force.

subset: commoncrawl


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Frontier Airlines - with new owners, a new management team, and a new logo on its planes - is coming to Philadelphia with flights to seven cities.
Denver's hometown airline will announce Tuesday nonstop flights from Philadelphia International Airport to Miami, Orlando, and Tampa, Fla., and Cancun, Mexico, in December, and to Atlanta, Charlotte, N.C., and Chicago next spring.
"These are underserved markets with very high fares," Frontier chief executive officer David Siegel said. "We're going to expand the market, stimulating it with low fares and dropping in a little bit of capacity."
Frontier hasn't flown scheduled service from Philadelphia since January 2013, soon after it began flights from Trenton-Mercer Airport.


text: Reality TV Female Farmers Find Fame And Fortune On Reality TV Show By Malaka Gharib • Mar 10, 2016 Carolina Chelele is a contestant on a popular reality TV show. It's not about dating, housewives or survival. It's about ... farming. Specifically, farming by females. Vicci Martinez from Tacoma in finals of "The Voice" tonight By Charla Bear • Jun 28, 2011 NBC / Lewis Jacobs/NBC A woman who was born and raised in Tacoma will perform in the last round of reality TV singing contest "The Voice" tonight. The competition has made the local rocker a familiar face to millions of people around the world.


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It's really pretty pointless to put much emphasis on the first preseason game, but there's always plenty to absorb, analyze and criticize. That was clearly the case today for the San Francisco 49ers, who beat the Indianapolis Colts 37-17 (don't read too much into that score) but whose first team offense was far from sharp.
Here are some impressions:
1. Quarterback Alex Smith played into the second quarter and showed the same flaws in the game that he has in training camp. When Smith misses with his passes, he misses high, although one possible touchdown to tight end Vernon Davis was thrown behind the receiver. Presumably, Smith will get better with time, but his misfires and a fumble by running back Michael Robinson on the first offensive play of the game made for a poor start.
2. Starting running back Frank Gore didn't play, but the performance of rookie Anthony Dixon put Dixon at the front of the pack for the role of No. 2. Dixon came in with the second team and immediately gave the 49ers what they're looking for – a straight-ahead runner who loves to bang bodies but who also has some nifty moves. He totaled 100 yards on 21 carries and one touchdown (with the help of a nice straight-arm). He still needs work as a pass blocker, but the job as Gore's backup is his, at least right now.
3. The newly constructed offensive line got plenty of work, with rookies Anthony Davis and Mike Iupati playing into the third period with second-stringers. Iupati, the left guard, is a good one and seems to know where to be and what to do. Davis, the right tackle, will benefit from the preseason. In the first quarter, he was called for a false start and then gave up a quarterback pressure when Colts veteran Robert Mathis got past him easily. Center David Bass had clean exchanges with Smith.
4. There were some notable performances by non-starters. A few quick hits: Safety Reggie Smith scored the Niners' first TD with a 91-yard interception return off a Curtis Painter pass in the second quarter. Safety Taylor Mays made a nice open-field tackle of Donald Brown for a three-yard loss. Linebacker Diyral Briggs had an interception late in the second quarter but gave it back when he fumbled the ball. Nose tackle Ricky Jean Francois batted away a pass attempt in the third period. Linebacker Mike Balogun had six tackles and one interception. Bruce Davis, signed when Kentwan Balmer went AWOL, had one sack and six tackles.
5. Quarterback Nate Davis entered the game in the third quarter and finished 5 of 6 passing for 84 yards. He's been the team's No. 3 QB in camp, but he showed he might be capable of pressing No. 2 David Carr.
6. Rookie Kyle Williams helped himself in an effort to win the job as the 49ers' punt/kick returner. He had one kickoff return for 28 yards and returned a punt for 36 yards. Ted Ginn Jr. was the frontrunner, but he was just so-so, and Bobby Guillory did himself no favors when he fumbled a punt in the fourth quarter.


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These large 5 1/2" acorns are sure to be a crowd pleaser! Make one or a pile, use them in a bowl or as ornaments on a fall tree. These can be used through Thanksgiving and the holidays...long after you put away that jack o' lantern! Cinnamon give the acorn it's great look...so buy it in bulk!
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Skip to comments.Evangelicals: Change of Heart toward Catholics
Posted on 07/29/2008 4:39:52 PM PDT by annalex
click here to read article
I'm saying people can love, hate, whatever, without God in their lives. It's emotions that we've been given by God to use as we wish. Just because He made love doesn't mean that only Christians CAN love. Get it?
He said "I think..."
Mostly, you're just embarrassing yourself now.
Glad you agree again with the Catholic Church.
When you decided to use hitler as an example of love it's very telling.
I'll keep you in prayer.
If they are going to go to hell and if God is omniscient, then God created them knowing full well that he was going to send them to hell. So no matter how you slice it, they were destined for hell before they were created.
God did not have to create those he knew he was going to send to hell, but he did.
thus God is a partner of the devil and zeus like
God is the one who sends people to hell, not the devil.
Tell me, did God create the devil knowing that he would turn out the way he did?
You don't think people who have sexual relations before marriage can't really love? Hmmm. I agree they shouldn't be having sex before marriage but not really love? That's a bit preposterous.
Not the case at all. Foreknowledge is not foreordination.
Conflating the two is perhaps the fundamental flaw in the error of double predestination.
The work of the devil leads them to use their free will poorly. The justice of God sends them to hell for it.
Yes, I know I did. What's the problem?
Nor apparently did you.
I told you not to post to me any more.
I told you not to post to me anymore.
You are something else, Petronski. Please don't bother posting to me any longer. You just live to insult people.
You are changing the subject. The point was your arrogance in attempting to void the baptisms of about a billion people.
I used him because he is the epitome of evil. But even he could love someone. Even the heathen love. Don't bother praying for me with your attitude. It will never be answered.
Please do not attempt to read my mind or make this personal. It is not about me. It is about the validity of infant baptism.
Nothing YOU can say can revoke the valid Trinitarian Baptisms of about a billion people. They are all quite valid in the eyes of God and His Church--the Catholic Church.
Now you seem to claim his prayers will never be answered.
And yet you lectured me on arrogance?!?
I'm telling him not to bother praying for me with his attitude about me because those will never be answered. Please do not post to me any longer.
When you post to an open thread, you can expect replies from all directions.
When you pretend to know whose prayers will not be answered, you should expect derisive replies.
It is an open thread.
If you wish that your statements not receive replies, I recommend private messages or caucus threads.
Good God Almighty!
"MOM! Tell Billy to quit looking at me! He's looking at me, Mom!"
Honestly. Some of these people will demand that you not post to them, and then sooner or later, they'll post to you, in spite of what they said.
Is the RF the place where people come to act out their pathology? Sometimes I wonder.
Try not reading it.
You just live to insult people.
You make the mistake of putting God within time and thus cannot comprehend that everything is NOW with God eternally.
The creation of us all is one NOW to God and cannot change from the eternal love created by Him freely.He created us out of love in one NOW to freely Choose Him and Freely love Him or reject Him
Your God is an evil zeus who lives within the time of which the human mind and makes sacrifice to the devil.
Are you making this personal?
You have no choice in who I decide to pray for and to decide for God what prayers are answered.
Have your own way. I really don't care.
No offense but you're being a whiny baby.
Please do not post to me again.
Please do not bring thin skin to open threads. According to guidelines, it makes you the disruptor.
""Your God is an evil zeus who lives within the time of which the human mind and makes sacrifice to the devil.""
Should read
Your God is an evil zeus who lives within the time of the comprehension of human mind and makes sacrifice to the devil.
Can I post to you? I'm very nice in person and have 2 cats.
I have a neurotic miniature poodle named Scoobie and a feral tomcat named Aretha.
Just, you know, for the record.
I'm sorry your having a difficult day ,dear sister.
Perhaps you should take a break and spend more time in prayer ?
That sounds about right.
Complaints from the two unfortunate kids who have to sit in that weird third seat in the back of the station wagon that faces the wrong way.
I have a mastiff and a minpin. They are beautiful, and well bred. I think their pedigrees are longer than my own....:D
Just sayin.
That is an absurd claim, which reveals an inability to understand numbers. It is based on comparing a 2007 study that showed 64 million Catholics with the 2008 Pew study that supposedly showed 54 million. However, the Pew study did NOT show 54 million Catholics. It showed that 24% of Americans are Catholic. Since the US population is about 306 million, that translates into about 74 million Catholics. The 54 million figure is presumably the number of ADULT Catholics. The Pew study itself says explicitly that the percentage of the US population that is Catholic has remained constant over recent decades -— which is in fact the case, as many studies have shown. The Pew study does not say that the Catholic population has declined -— it explicitly says otherwise. They do say that over the last several decades many Catholics have left the Church. But they also say that this has been offset by a combination of higher birthrate, immigration, and conversions to Catholicism, so that the Catholic percentage of the population has remained steady for the last 40 years. The Protestant percentage of population, on the other hand has shrunk dramatically.
As far as why the Southern Baptists have started to decline, the answer is probably pretty simple: low birthrate. Everyone knows that the "mainline" Protestant denominations have declined drastically in large part because of extremely low birthrates. What is less well-known is that even most "evangelical" groups have low birthrates -— and this includes the Southern Baptists, who are slightly older on average that the US population. According to the Pew study -— readily available online -—the great majority of Protestant groups have low birthrates. The high-birthrate exceptions are the Pentecostals, the non-denominational evangelicals, and black Protestants. The Catholics have pretty healthy birthrates, even leaving out the hispanics. The Catholic Church in the US continues to be one of the few "denominations" with steady growth year after year.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.


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Women Inspiring Service and Education is hosting an evening of magic Oct. 5 to raise funds for a nonprofit group that offers free services to grieving children, teens and adults.
Tickets are $35 per person for "A Magical Evening" at Carson Valley Inn, and includes a prime rib dinner and an evening of magic featuring Dan Kimm of Hypnotic.
Brooke Roberts, WISE community outreach chairman, said proceeds will go to the Douglas Center for Hope and Healing.
"Our group picks a charity to support for two years, and we raise money by having fundraisers," Roberts said.
Douglas Center for Hope and Healing is close to her heart, she said, because it was founded by her sister, Jodi Wass.
The center offers peer support groups to children, teens, adults and families coping with the loss of loved ones in Douglas County, Carson City, Lake Tahoe and surrounding areas.
"We get nominations from our members, and when it was narrowed down, DCHH really struck a chord," Roberts said. "We all know somebody who has gone through the loss of a loved one. Jodi came to our meeting and made a presentation. It touched our hearts very deeply. Jodi is my sister and I was pretty darned excited when we made the decision," Roberts said.
Doors open at CVI at 5 p.m. Prior to the headliner, magician Thomas Wiese will be performing tableside magic.
The evening also includes raffle prizes, a 50-50 lottery and dessert auction.
Roberts said WISE is accepting donations for raffle and auction items through Sept. 30.
She can be reached via email at firstname.lastname@example.com., or (775) 790-3797.
Tickets may be purchased online at www.nvwise.org; Body Language Day Spa, 1478 Fourth St., Suite B, Minden; and the Douglas Center for Hope and Healing, 1677 Lucerne St., Suite B, Minden.
They will be available at the door the evening of the event for $40.
Roberts described the event as a "PG-13" kind of event.
"We're gearing it toward a 'date night,' but teenagers might get a kick out of it," she said.


text: DANNY T Dub & Dancehall Leeds DUB/DANCEHALL DJ + PRODUCER FROM LEEDS UK RELEASES Mungos HiFI - Gunman Posse .ft Peter Metro & Squiddly (Danny T & Tradesman Remix) http://scotchbonnet.net/shop/product.php?id_product=1511 Reggae Roast - Tonight .ft Earl 16 7" http://www.reggaeroast.co.uk/release/reggae-roast-tonight-feat-earl-16/ Danny T & Parly B - Dreader than Dread 7'' http://www.juno.co.uk/products/danny-t-parly-b-dreader-than-dread/509310-01/ Skin & Pull Out EP 12'' http://www.scotchbonnet.net/shop/product.php?id_product=1432 No Rest EP http://www.junodownload.com/artists/Red+Eye+Hifi/releases/?show_tracks=all Music Unity and Respect EP Vol.1 https://itunes.apple.com/us/album/music-unity-respect-ep/id550401320 Music Unity and Respect EP Vol.2 https://itunes.apple.com/us/album/music-unity-respect-pt.-2/id845742402 Iron King EP http://www.junodownload.com/products/iron-king-ep/1681068-02/ Danny T is a Leeds based music producer and DJ, who works alongside Tradesman, specialising in Dancehall & UK Steppas. Danny T and Tradesman have a burgeoning reputation for producing and mixing innovative and modern Reggae music, which is heavily influenced by the 80's and 90's sound of Classic Reggae. This has led them to play at some of the biggest nights in Leeds and other cities in the UK and Europe. Most respectively, they hold residency at SUBDUB's 'Dancehall Science' event. Their growing success has been ignited by the support they have received from the biggest most influential producers and artists in the British Reggae and Dub scene. This includes Iration Steppas, OBF, Mungo's HiFi, Dubmatix, Riddim Tuffa, Reggae Roast and many other artists across the globe. Since Danny T and Tradesman started producing, they have played alongside and worked collaboratively with Iration Steppas, Nucleus Roots, Dubmatix, Dub Conductor, Part2Style, Sammy Gold, Shanti D, Warrior Queen , Parly B, Daddy Freddy, Lenny Ranking, Urban Vox, Nanci, Ranking Levy , Shire Roots, Lion Dread, OBF, Dubkasm, Vibronics, Mungo's HiFi , Riddim Tuffa, The Bug, Stand High Patrol, Exodus, Daddy Freddy , Kenny Knots, Pupa Jim and Miss Red... DANNY T's tracks Danny T & Tradesman - A Fi Fly Out! .ft Daddy Lizard (Remix) by DANNY T published on 2016/08/21 16:34:11 +0000 Danny T & Tradesman - Here I Am .ft Dark Angel by DANNY T published on 2016/07/30 22:31:32 +0000 Danny T & Tradesman - Fight mi Down .ft Tall Rich by DANNY T published on 2015/08/08 20:18:25 +0000 Danny T & Tradesman - Call me Rambo .ft Shanti D by DANNY T published on 2015/05/23 18:58:51 +0000 Red Eye HiFi - Need Some Rest .feat Parly B (Danny T & Tradesman Remix) by DANNY T published on 2014/06/27 19:50:58 +0000 Jah Screechy - Walk and Skank (Danny T and Tradesman Remix) by DANNY T published on 2014/04/10 18:57:20 +0000 Part2Style .feat Tippa Irie - Ragamuffin (Danny T & Tradesman Remix) by DANNY T published on 2014/02/25 13:10:37 +0000 Danny T .feat Cookah (KPC's) - Herbman Regime by DANNY T published on 2013/09/05 20:36:02 +0000 Danny T & Parly B - Dreader than Dread 7" Irish Moss Records by DANNY T published on 2013/08/07 20:31:32 +0000


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A detailed Bordeaux vintage guide and summary covering the years 1900 to today with detailed information on the different Bordeaux vintage conditions, growing seasons, harvest reports, temperatures and picking dates. Links are offered for buying tips that focus on wines that offer the best quality and price value ratio from every important year in the Bordeaux vintage Guide.
If you want to read about Bordeaux wine producers in different Bordeaux appellations: Links to all Bordeaux Wine Producer Profiles If you are interested in learning more about Bordeaux wine, we offer numerous articles on everything about Bordeaux wine, from a history of the Bordeaux region and the famous 1855 Classification, to the grapes used to produce Bordeaux wine and even vintage summaries covering Bordeaux wine from 1900 to today: All About Bordeaux Wine Guide
The links on the left side of the page provide you with detailed articles on all the best Bordeaux vintages from the legendary year of 1945, all the way up to today's current Bordeaux vintage. Just click on the link that interests you in The Bordeaux Vintage Guide. The Bordeaux Vintage Charts 1959 through Today ranks each vintage and provides you with current information on how the vintages are drinking today, and if the wines are ready to drink, need more time in the cellar, or if they are past their optimum maturity date.
If every picture tells a story, every harvest relates a story as well in this Bordeaux Vintage Guide. Things are different in Bordeaux today. When you look at the advances in modern Bordeaux wine making and vineyard management techniques, coupled with the willingness to perform the necessary amount of selection in the vineyards and cellars needed to produce the best wine possible, it appears that bad Bordeaux vintages are now a thing of the past. If you don't agree, look at recent difficult years like 2013, 2011 and 2007 as recent examples.
Think of it like this, a wet, cool year like 2007 would have been a disaster 20 years ago. Today, while dilute, some nice, early drinking wines were produced. For different reasons, 2011 Bordeaux and 2012 Bordeaux would have produced extremely weak wines for previous generations. You can learn more about specific years in the Bordeaux Vintage Guide.
The style of Bordeaux wine varies from year to year. This is due to the different vintage characteristics shaped by the weather, choices made by the winemaker and the soils and terroir of Bordeaux These variances are what gives that uniqueness to Bordeaux wine. Of course not all vintages are created equally.
There are basically Four different types of Bordeaux vintages which can be subdivided into two categories. You have the early drinking and classic vintages on one end of the spectrum. On the other side of the vineyard, you have the highly sought after, special vintages.
With the highly sought after collectible years, you have Bordeaux at its best. These years can be split into two different styles. You have years that are supple, sexy, opulent and ripe. The wines are rich and concentrated. The tannins are silky smooth and many of the wines can be enjoyed in their youth and as they age. Those qualities are found in for example: 2009, 2003, 2001, 1990, 1989, 1985, 1982, 1964, 1959, 1953, 1950, 1947, 1929 and 1928.
But there is a completely different style of Bordeaux wine that is also highly collectible. Those years produce stunning wines with intensity, concentration, tannin and structure for serious aging. Many of those wines are not fun to drink early, especially the Cabernet Sauvignon bases wines from the Left Bank . Examples of those vintages are 2010, 2006, 2005, 2000, 1996, 1995, 1986, 1975, 1970, 1966, 1961, 1945 and 1928. The top wines from those years could take decades to develop and mature.
The other category of Bordeaux vintages you often encounter is quite useful, as the wines can be enjoyed in their youth, while you wait for the bigger vintages to develop and mature. There are the soft, light, early drinking vintages like 2012, 2011, 2007, 1999, 1997, 1987, 1981 and 1979 for example. Another example of a small vintage are the cooler years that produce classic Bordeaux styled wines that require age. They can be a bit stern and lower in alcohol, yet they can often pleasure before they are 100 years of age. For example, 2004, 2002, 1994, 1988, 1983 and 1978.
The unique characteristics discovered in different Bordeaux vintages is a part of what makes wines collecting interesting and fun. That is a good reason to use our Bordeaux Vintage Guide. Comparing wines from the same producer in different years allows you understand the chateau. Comparing wines from a wide array of producers from the same year, lets consumers to discover what took place during specific vintages.
Knowledge and technology have made it possible to produce better Bordeaux wine than ever before. But no amount of human intervention can alter the unique personality awarded by nature to each Bordeaux vintage.
To read details on every Bordeaux vintage from the legendary 1945 to today's current Bordeaux vintage, just click on the link that interests you in The Bordeaux Vintage Guide:


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You have probably seen soda can crafts in your neighbor's garden, at craft fairs, and on craft web sites. This is a guide about crafts using soda cans.
Pierce the side of the can near the top with a knife.Carefully cut out the top, beginning where you pierced it. Then cut down the side and cut out the bottom.
Cut shapes freehand or use a diecutter or trace a pattern on one side with a marker and cut them out. Chain stitch cord or thread or string in between each shape or string them in whatever way you want to adding beads if you like.
I used metallic cord so it should last a little while if I decided to hang it outside.
It is about 8 feet long.
This is a guide about making a soda can lantern. Recycle your soda cans by making decorative lanterns to use on your patio or in the garden.
To make a cheap wind chime, I used a 1x4 inch board, cut 4- 3 1/2 inch pieces, and drilled 4 small holes, 3 inches apart, and 2 holes in the top of the board. I used fishing line to make the hanger, and I use soda cans, any kind of soda will work. I paint the board the same color as the cans. I use fishing line to hang the cans.
I have a Redneck or Hillbilly Windchime.
By Barbara from Spring Hill, FL
Approximate Time: 1 hour
You now have a six pack carrier that would make a delightful gift for those summer barbecue parties coming up, leave a couple for your host and hostess to enjoy after all their guests have gone home.
By Ann
I saw at a craft fair that someone had these model airplanes and models boats and cars made out of soda cans and beer cans. I've been searching all over for how to make a sailboat out of beer cans. Can anyone help me?
I went to a bar last night that had these model airplanes hanging up over the bar. I asked about them because I really want one. They were made by the owner's friend, son. The owner is on holiday but when he gets back I'm gonna get his contact details. You have to collect the cans yourself and then he charges 10 pound to make it for you.
I would like directions on making a wallet from tin can or soda pop cans. I would like other projects made with soda cans as well.
KATHI from Iron River, MI
On you-tube there are videos that show you how to make purses from soda cans. More than likely there is a video for a wallet there also. Basically you can cut squares or rectangles from the can, then you punch holes in the squares or rectangles with a regular hole punch (I would use a leather punch if you have one - with 1/4" holes for the punch) all around the square. You then crochet with a sturdy yarn or string around the squares. Attach the squares together with crochet. You could use Velcro for the clasp. You can use paint or duct tape before punching the holes if you want it one color.


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Biography of Freddie Mercury
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Biography of Russell Crowe
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Biography of Shahrukh Khan
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Biography of Bob Marley
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Biography of Robert Downey Jr.
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Biography of Kat Bjelland
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Biography of Mylène Farmer
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Biography of Bob Dylan
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Biography of Ryan Reynolds
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Biography of Alexander the Great
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Biography of Vincent Cassel
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Biography of Winona Ryder
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Biography of Russell Brand
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Biography of Rachel McAdams
Rachel McAdams (born November 17, 1978 (birth time source: The Rachel McAdams Handbook - Everything You Need To Know About Rachel McAdams by Emily Smith)) is a Canadian actress. She is known for her roles in the Hollywood films Mean Girls, The Notebook and Wedding Crashers, which all proved to be successful at movie theaters. Early life McAdams was born in London, Ontario and grew up in nearby St. Thomas. Her father, Lance, is a truck driver, and her mother, Sandra, is a nurse. She has a younger brother, Daniel, and a younger half-sister, Kayleen. She took up competitive figure skating at the age of four and acting at age thirteen at a summer theater camp in London, Ontario named Original Kids. When the company extended to a year-round company, she was invited to continue with them. Sh...
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Jean Dujardin (born 19 June 1972) is a French actor and comedian. He has worked notably with director Michel Hazanavicius, starring in his OSS 117 spy parodies. His starring role in Hazanavicius' silent movie The Artist, playing actor George Valentin, received widespread acclaim. The role won him the Golden Globe Award for Best Actor in a Musical or Comedy, the BAFTA Award for Best Actor in a Leading Role, the Screen Actors Guild Award for Outstanding Performance by a Male Actor in a Leading Role, the Cannes Film Festival Best Actor Award, and the Academy Award for Best Actor. He is the first French actor to win the Academy Award for Best Actor. Early life Dujardin was born and raised in Rueil-Malmaison (Hauts-de-Seine, Île-de-France), a commune in the western suburbs of Paris, Franc...
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Biography of Sting (musician)
Gordon Matthew Thomas Sumner, CBE (born 2 October 1951), better known by his stage name Sting, is an English musician from Newcastle upon Tyne. Prior to starting his solo career, he was the principal composer, lead singer and bass player of the 1970s/1980s rock band The Police. Personal life Sting married actress Frances Tomelty from Northern Ireland, on 1 May 1976. Before they divorced in 1984, the couple had two children: Joseph (born 1976) and Fuchsia Catherine (born 1982). Joe is following in his father's musical footsteps and is a member of the band Fiction Plane. In 1982, shortly after the birth of his second child, Sting separated from Tomelty and began living with actress (and later film producer) Trudie Styler. The couple eventually married in 1992. Sting and Styler have fo...
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Biography of Cher (entertainer)
Cheryl Sarkisian LaPiere (better known as Cher) (born on May 20, 1946 (birth time source: Contemporary American Horoscopes , Astrodatabank)), is an American actress, singer, songwriter, and entertainer. Among her many accomplishments in music, television, and film, she has won an Academy Award, a Grammy Award, an Emmy Award and three Golden Globe Awards. Cher first rose to prominence in 1965 as one half of the pop/rock duo Sonny & Cher. She also established herself as a solo recording artist, releasing 26 albums, numerous compilations and tallying 22 Billboard Top 40 entries over her career. These include twelve Top 10 singles and four number one singles. She became a successful television star in the 1970s, and a well-regarded film actress in the 1980s. In 1988, she won the Academy ...
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Biography of Louis XIV of France
Louis XIV (baptised as Louis-Dieudonné) (September 5, 1638 September 1, 1715) ruled as King of France and of Navarre. He acceded to the throne on May 14, 1643, a few months before his fifth birthday, but did not assume actual personal control of the government until the death of his First Minister ("premier ministre"), Jules Cardinal Mazarin, in 1661. Louis would remain on the throne till his death just prior to his seventy-seventh birthday in 1715. The reign of Louis XIV, known as The Sun King (in French Le Roi Soleil) or as Louis the Great (in French Louis le Grand, or simply Le Grand Monarque, "the Great Monarch"), spanned seventy-two yearsthe longest reign of any major European monarch. During that period of time he increased the power and influence of France in Europe, fighti...
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Jean Nicolas Arthur Rimbaud (October 20, 1854 November 10, 1891) was a French poet, born in Charleville. His influence on modern literature, music and art has been pervasive. Early life and work Arthur Rimbaud was born into the provincial middle class of Charleville (now part of Charleville-Mézières) in the Ardennes département in northeastern France. He was the second child of Captain Frédéric and Vitalie Rimbaud (née Cuif). As a boy he was a restless but brilliant student. By the age of fifteen he had won many prizes and composed original verses and dialogues in Latin. In 1870 his teacher Georges Izambard became Rimbaud's literary mentor and his original French verses began to improve rapidly. He frequently ran away from home and may have briefly joined the Paris Commune of 1871...
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Eva Gaëlle Green (French: ; Swedish: ; born 6 July 1980) is a French actress and model. She started her career in theatre before making her film debut in 2003 in Bernardo Bertolucci's controversial The Dreamers. She achieved international recognition when she appeared in Ridley Scott's Kingdom of Heaven (2005), and portrayed Vesper Lynd in the James Bond film Casino Royale (2006). In 2006, Green was awarded the BAFTA Rising Star Award. Since 2006, Green has starred in independent films Cracks (2009), Womb (2010), and Perfect Sense (2011). She has also appeared in the television series Camelot (2011), and played Angelique Bouchard in Tim Burton's big-screen adaptation of Dark Shadows (2012). In 2014, she played Artemisia in the 300 sequel, 300: Rise of an Empire, and Ava Lord in Frank Mi...
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Biography of Linda Goodman
Mary Alice Kemery popularly known as Linda Goodman (April 9, 1925 (birth time source: Astrodatabank, BC) October 21, 1995) was a New York Times bestselling American astrologer and poet. She is notable as the author of the first astrology book to make The New York Times Best Seller list. Early life and background Linda Goodman was born in Morgantown, West Virginia. Although Goodman never revealed her year of birth, swearing even her father to silence, it emerged posthumously that she was born in 1925. According to data collector Frank C. Clifford, Linda was born on April 9, 1925 in Morgantown, West Virginia at 6:05 a.m. Clifford cites Linda's birth certificate as his source. Her father's name was Robert Stratton Kemery. Her mother's maiden name was Mazie McBee. By her own account sh...
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Biography of Billie Holiday
Billie Holiday (April 7, 1915 July 17, 1959), born Eleanora Fagan and later called Lady Day, was an American jazz singer. Billie Holiday had a difficult childhood, which greatly affected her life and career. Much of her childhood is clouded by conjecture and legend, some of it propagated by her autobiography, Lady Sings the Blues, published in 1956. This account is known to contain many inaccuracies. Her professional pseudonym was taken from Billie Dove, an actress she admired, and Clarence Holiday, her probable father. At the outset of her career, she spelled her last name "Halliday," presumably to distance herself from her neglectful father, but eventually changed it back to "Holiday." Holiday's grandfather was one of 17 children of a black Virginia slave and a white Irish pla...
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Biography of Jeff Buckley
Jeff Buckley (November 17, 1966 May 29, 1997), born Jeffrey Scott Buckley and raised as Scotty Moorhead, was an American singer-songwriter and guitarist. Known for his ethereal singing voice, Buckley was considered by critics to be one of the most promising artists of his generation after the release of his critically acclaimed 1994 debut album Grace. However, at the height of his popularity, Buckley drowned during an evening swim in 1997. His work and style continue to be highly regarded by critics and fellow musicians. Discography Albums Year Title Release Date 1993 Live at Sin-é November 23, 1993 1994 Grace August 23, 1994 1995 Live from the Bataclan October 1995 1998 Sketches for My Sweetheart the Drunk May 26, 1998 2000 Mystery White Boy May 9, 2000 2001 Live...
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Joan of Arc, also known as Jeanne d'Arc, (January 1412 May 30, 1431) was a national heroine of France. She asserted that she had visions from God which told her to recover her homeland from English domination late in the Hundred Years' War. The uncrowned King Charles VII sent her to the siege at Orléans as part of a relief mission. She gained prominence when she overcame the dismissive attitude of veteran commanders and lifted the siege in only nine days. Several more swift victories led to Charles VII's coronation at Reims and settled the disputed succession to the throne. The renewed French confidence outlasted her own brief career. She refused to leave the field when she was wounded during an attempt to recapture Paris that autumn. Hampered by court intrigues, she led only minor co...
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Biography of Princess Stephanie of Monaco
Princess Stéphanie of Monaco (Stéphanie Marie Elisabeth Grimaldi, born 1 February 1965) is the youngest child of Grace Kelly and Rainier III of Monaco. She has been at one time a singer, swimwear designer, and fashion model; her mother lovingly called the princess her "wild child" she is the sister of Albert II of Monaco and Princess Caroline. She was the passenger in the car when her mother was killed in an accident on a mountain road 13 September 1982. Rumours persist to this day that Stéphanie was driving. She was unable to attend her mother's funeral because she was in hospital with injuries from the crash. Fashion In 1983, after her physical recovery from the accident, Stephanie started an apprentice program at Christian Dior under the direction of head designer Marc Bohan, w...
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Biography of Arnaud Montebourg
Arnaud Montebourg (French pronunciation: ; born 30 October 1962 (birth time source: Didier Geslain)) is a French politician who served in the government of France as Minister of Industrial Renewal from May 2012 to August 2014. Between April 2014 and August 2014, as a member of the short-lived first Valls government, Montebourg held additional ministerial responsibilities whereby his overall brief encompassed the Economy, Industrial Renewal and Information Technology. He was succeed by former investment banker Emmanuel Macron. Previously he served as Deputy for the sixth district of Saône-et-Loire in the National Assembly of France from 1997 to 2012, and he was President of the General Council of Saône et Loire from 2008 to 2012. A member of the Socialist Party, Montebourg was a c...
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Biography of Patrick Bruel
Patrick Bruel (born Patrick Maurice Benguigui, on May 14, 1959 in Tlemcen, Algeria) is a Jewish French singer, actor, and professional poker player. Although Bruel aspired to be a football (soccer) star as a youth, he decided to pursue singing after seeing Michel Sardou in 1975. His first success came as an actor, however, in 1979's Le Coup de sirocco. He continued acting in films, on television and in the theater while pursuing his singing career. His first single, "Vide" ("Empty"), released in 1982, was not a success, but the follow up, "Marre de cette nana-là" ("Fed up with that chick"), was a hit. In 2003, he had his last name officially changed to Bruel-Benguigui, his stage name with his birthname, before his partner Amanda Maruani gave birth to his first child, Oscar, on August...
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Françoise Sagan (June 21, 1935 (birth time source: Gauquelin, Didier Geslain)September 24, 2004), real name Françoise Quoirez, was a French playwright, novelist and screenwriter, best known for strong romantic themes involving middle-class characters. Sagan was born in Cajarc, Aveyron, where she lived for the first few years of her life, until her family moved to Lyon at the outset of World War II. She failed entrance examinations to the Sorbonne in 1953 mainly due to her active nightlife in the Paris clubs.Though notorious all her life for her extravagant lifestyle, she would later attend school there but without graduating. Her first novel was published in 1954, at the age of 18. Bonjour Tristesse (meaning "Good Morning, Heartache," the French translation of the Billie Holiday son...
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Biography of Alexander Skarsgard
Alexander Johan Hjalmar Skarsgård (Swedish pronunciation: ; born August 25, 1976, in Stockholm, Sweden (birth time source: http://sasstrology.com/2010/01/kate-bosworth-and-alexander-skarsgard-jupiter-sextile-mars.html)) is a Swedish actor and director. He is the son of Swedish actor Stellan Skarsgård and Dr. My Guenther and the brother of actor Gustaf Skarsgård (born 1980), Sam Skarsgård (born 1982), Bill Skarsgård (born 1990), Eija Skarsgård (born 1992), Valter Skarsgård (born 1995) and Ossian Skarsgård (born 2009) Career Skarsgård has acted in several Swedish TV series and movies. In 2003 he was nominated for a Guldbagge for male supporting role in the movie Hundtricket - The movie. Since 2005, with his performances in Revelations and The Last Drop he has taken part in internation...
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Best route map between Elkhorn City, KY and Caswell Beach, NC. This route take about 461 Miles.
The distance and estimated time is placed on the right depending on the status of the road.
, 18:31
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Hotel Parco Dei Principi
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- Suites
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- TV Channel One Russia
- Beach
- Continental Breakfast
- Room service
Photos of Hotel Parco Dei Principi
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- Swimming pool
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- Suites
- TV Channel One Russia
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- Business Services
Historical Traveler Reviews Hotel Parco Dei Principi Sorrento
Great View, but very costly; April 2004
This hotel has a great view of the Bay of Naples, but it is not central to the city. It is about a 1/2 hour walk to the center of Sorrento. They do have a shuttle bus, complimentary, that runs almost every hour, to/from hotel/city center. Rooms were nice; they were spacious and clean. Restaurant was overpriced. There were a lot of hotels, perched on the same cliffs, that had the same wonderful views. This hotel was the most expensive hotel on our trip and based on the price and non-central location, I would not recommend it.
Romantic with Stunning Views
We stayed here in June of 2000....Located up on a cliff with stunning views overlooking the sea, this hotel, from what I remember, was formerly the grounds of a princess. Although her home was reconstructed as a hotel, much of the original grounds are still in tact which are absolutely beautiful. The area was quiet and serene, the room size was decent with OK decor, there was a pool and a private beach accessible by elevator ...overall, we'd give the hotel a 3.5 out of 5 in US standards, however, with thelocation and views, we'd bump it up to a 4 to 4.5. Quaint neighborhood with a couple of restaurants in the area, however if you drive down the hill to town, there is a lot of shopping, restaurants and things to see. Its definitely not a Sheraton, but truly a nice hotel, and we'd definitley stay there again.
Ponti's Pearl in the Med
I have stayed at this hotel for three years in a row and can't wait to return! I confess to being something of a retro design freak and a week at the Parco is pure timewarp heaven. It's clear from previous reviews that this hotel is not going to be everyone's cup of tea-it's certainly not going to be a lot of people's idea of what a five star hotel should be! However, if you bear in mind that the ricketty-looking dressing table in your room is worth far more than what your holiday cost, it might give a different perspective on things. Designed by architect Gio Ponti in the early sixties, the Parco is one of the few remaining hotels in the world to retain its original fittings and decor, painstakingly designed by Mr Ponti, right down to the floor tiles, each room having a different pattern. The hotel was discreetly renovated a couple of years ago, while faithfully retaining or replacing original features. The comparative starkness of the rooms, decorated in blue and white reflects the colours of the surrounding sea, while being a cool sanctuary from the searing outdoor heat. The view from the balcony is probably one of the world's best with Vesuvius to the right, Capri to the left and the twinkling lights of Naples across the bay. Service is superb, however the food leaves a little to be desired but is nonetheless passable. If you are planning on going, be prepared for a quirky experience-if you want swags, gold taps and plush carpets, your best bet's going to be the Excelsior Vittorio just up the road. If you're walking into town, take the back lanes route as the main road is potentially lethal! that said, The beautiful extensive grounds of the hotel and the space age swimming pool should keep any need for forays into the outside world to a minimum.
The worst
Other than the nice view if your have an ocean front room, this hotel is a disaster. It was designed to amplify noise, no carpeting, the beds and pillows are like wood, and the shower spits out less water than the toilet. Better off sleeping on the beach!
A cheap motel with the price of a 5 star hotel
We spend three days at the hotel and we fell like they treat us as a second class guest.1- The bathrooms were dirty2- Not a friendly staff3- Never gave us wakeup call that we ask.4- The food at the restaurant was not to good5- the bed was so hard that the floor will adjust better to your body.They just have become a 5 stars hotel but they treat us like if they were a cheap motel.
Awesome Hotel
Rooms were very large, bedroom, living room, bathroom. The gardens and views were stunning. Really nice salt water pool, cool black sand private beach. Very peaceful and beautiful, definately recommend it and will be going back, price was perfect! Fun piano bar!
A cool hotel
We were not sure whether we liked the decor to begin with but it really grew on us. All blue and white '60s minimalism with loud geometric patterned tiles in immaculate, newly restored condition.Together with the stark lighting the ambience is "cool" but somehow this contrasts well with the warmth of Sorrento outside. The location is what you really pay for, the views across the Bay of Naples to Mt Vesuvius are nothing short of spectacular. The hotel is situated a 20mins walk from the centre of Sorrento which I think is a positive - the location is peaceful and the hotel has its own beach and swimming cove at the base of the cliff which some of the de-luxe hotels in town do not. The staff were really friendly and attentive. The food was good but overpriced in my mind. Would I go back? Definitely.
Enjoyed the peaceful, beautiful setting
A nice hotel in a park like setting with lots of trees, 2 swimming pools and a private beach. The hotel is located a 20 minute walk from the town and has a shuttle service - although it only seats 8 and does not run very often.Staff was helpful. Breakfast is served on a terrace overlooking the water.
Groovy Hotel
The setting of the Parco Dei Principi is spectacular, perched above the cliffs with a huge garden and private "beach" and breakwater (this is as much or more beach than any other hotel in Sorrento, due to the cliffs).
The hotel building itself is "new" though, built during the sixties and totally ingrained with a Jetsons of the Mediterranean vibe and period decor throughout -- so it was not what we were expecting and it took as a while to adapt.
You'd never confuse the furniture or the interior of the room with a traditional 4 or 5 star hotel, but the setting and view are spectacular, and that's what makes this hotel work.
Definitely rent a scooter during your stay. Cabs are pricey for a 3 min. drive, the walk is a bit of a trudge after a while, and you're going to want to go to Positano and Pompeii, for which you'll need transport anyway (and they're so fun).
Stunning views
The room we had was newly renovated and looked straight out over the Med. The staff were excellent and extremely helpful. The food in the restaurant was just about the best we had in Italy. The pool was peaceful and the beach very private. Their shuttle bus makes it easy to get into Sorrento but the 20 minute walk was nice anyway. I would thoroughly recommend staying here.
TripAdvisor Reviews Hotel Parco Dei Principi Sorrento
Travel Blogs from Sorrento
Surreal in Sorrento
... Ginger Ale. By my freshman year of high school, I had lost both of my grandparents. As I became an adult, I became increasingly aware of everything they could've taught me about Italian culture that I never had the opportunity to learn. I had great aunts and uncles, and I loved that when we went to visit them, they would put everything cookie and sweet morsel they had on the table, and as soon as you could start seeing the bottom of the plate, they ...
... and also I don't really think they can afford to do any more. We were pleased to go to Herculaneum as Pompei was quite busy and we saw similar things at both.
Pompei was huge we only had 2 hours there so only saw the highlights but it was enough. It was amazing what they uncovered and what has still been preserved after the volcano and subsequent fires.
Being the first Sunday of the month both places had free entry - an added ...
Herculaneum, Vesuvius, Oplontis and Sorrento
... train to Ercolano and Herculaneum.
We found the right street that took us to the Garibaldi train station, on the Circumvesuviana line. The guy at the ticket desk told us to get a U5 day ticket, €6.50 so we can get on and off the train all day and still get to Sorrento. We had a short wait for the Sorrento train but realised that the first local train arriving at the station would take us to Ercolano, the stop for Vesuvius and Herculaneum. The route ...
Amalfi (a shopping day at Positano)
... so we had only the view of total darkness. (The Terrace dining opportunity is fnished for this year, because it is now too cold. The hotel food, and service were still sensational. I know if I were ever in this area, by land, that I would definitely stay at the Caruso in Ravello. After a wonderful, delicious dinner, and another hair-raising ride down the mountain... we vowed: "See you next year...." Back on Milena, the humidity was high, and there was very little air moving. ...
Crammed buses and delicious gelato
... raw chicken which had to be sent back. After lunch we wondered around town then decided to sort out the turn bus. Unfortunately there was a bus strike starting they weonky going once an hour and the crowds were huge. Lorraine then came to the rescue with the excellent idea of taking a boat trip back which she sorted out and organized. The boat trip was excellent taking us into the Positano bay then back along the coastline to ...


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HP Pavilion dv2699
Average of 1 scores (from 1 reviews)
Reviews for the HP Pavilion dv2699
Source: Trusted Reviews
It has style, it has performance and it's reasonably priced, which is all the ingredients you need for a great laptop computer. It may lack some niceties such as Draft-N wireless and it'll never be a gaming machine, but for entertainment and general use this is a great performer that will fill you with pride whenever you take it out of your bag.
(von 10): 9, Ausstatung 8, Leistung 9, Preis/Leistung 9
Single Review, online available, Long, Date: 02/11/2008
Rating: Total score: 90% price: 90% performance: 90% features: 80%
NVIDIA GeForce 8400M GS: NVidia GeForce 8400M GS is the DirectX 10 capable successor of the GeForce Go 7400 for laptops and technologically a slower 8400M GT video card (because of the smaller 64 Bit memory bus).
Only some 3D games with very low demands are playable with these cards.
» Further information can be found in our Comparison of Mobile Graphics Cards and the corresponding Benchmark List.
Intel Core 2 Duo: This is the Core Duo and Core Solo successor with a longer pipeline and 5-20% more speed without more power consumption. As an addition to the Core Duo design there exists a fourth decoder, an amplified SSE-unit and an additional arithmetical logical unit (ALU).
The Core 2 Duo for laptops is identical to the desktop Core 2 Duo processors but the notebook-processors work with lower voltages (0.95 to 1188 Volt) and a lower Frontside bus clock (1066 vs 667 MHz). The performance of equally clocked notebooks is 20-25% lower than Desktop PCs because of the lower Frontside bus clock and the slower hard disks.
The Core 2 Duo T7500 is a Merom based Core 2 Duo with 4MB Level 2 Cache. It is positioned in the middle class (in 2009) and performs on par with a modern P7550 or Turion II Ultra M640/M660.» Further information can be found in our Comparison of Mobile Processsors.
This display size represents a treshold between the small sizes of subnotebooks and ultrabooks and the standard-sizes of office- and multimedia laptops on the other hand. Laptops with that size are somewhat rare, nowadays.» To find out how fine a display is, see our DPI List.
2.5 kg:
Usually subnotebooks, ultrabooks and quite lightweight laptops with 12-16 inch display-diagonal weigh as much.
HP: The Hewlett-Packard Company, founded 1935, commonly referred to as HP, is a technology corporation headquartered in California, United States. HP specializes in developing and manufacturing computing, storage, and networking hardware, software and services. Major product lines include personal computing devices, enterprise servers, related storage devices, as well as a diverse range of printers and other imaging products. Other product lines, including electronic test equipment and systems, medical electronic equipment, solid state components and instrumentation for chemical analysis. HP posted US $91.7 billion in annual revenue in 2006, making it the world's largest technology vendor in terms of sales. In 2007 the revenue was $104 billion, making HP the first IT company in history to report revenues exceeding $100 billion. Market share regarding sales of personal computers in 2007 (market research IDC): HP 18.9 %, Dell 16.4 %, Acer 9.9 %, Lenovo 7.5 %, Apple 5.7 %
90%: There do not exist many models, which are rated better. The most ratings get ratings, which are a bit worse.
» Further information can be found in our Notebook Purchase Guide.


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Hunger Task Force - Farm Volunteer
Volunteers urgently needed between now and mid-June to transplant crops. Without your help we won't be able to provide healthy fresh food
This growing season we anticipate harvesting over 300,000 pounds of fresh produce that will be delivered free of charge to our network. The following is what we are looking for from our volunteers...
Different shifts are available-bring your friends!
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