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Are you Keisuke Hamada?Claim your profile
Publications (11)
- [Show abstract] [Hide abstract] ABSTRACT: Gene transcription is regulated in part through the assembly of multiple transcription factors (TFs) on gene enhancers. To enable examination of the mechanism underlying the formation of these complexes and their response to a phosphorylation signal, two kinds of higher-order TF–DNA assemblies were crystallized composed of an unmodified or phosphorylated Ets1 fragment, a Runx1(L94K) fragment and a CBFβ fragment on the T-cell receptor (TCR) α gene enhancer. Within these complexes, the Ets1 and Runx1 fragments contain intrinsically disordered regulatory regions as well as their DNA-binding domains. Crystals of the complex containing unmodified Ets1 belonged to space group P212121, with unit-cell parameters a = 78.7, b = 102.1, c = 195.0 Å, and diffracted X-rays to a resolution of 2.35 Å, and those containing phosphorylated Ets1 belonged to the same space group, with unit-cell parameters a = 78.6, b = 101.7, c = 194.7 Å, and diffracted X-rays to a similar resolution. To facilitate crystallization, a Runx1 residue involved in a hydrophobic patch that was predicted to be engaged in crystal packing based on the previously reported structures of Runx1-containing crystals was mutated.
Article: A Novel Allosteric Mechanism on Protein–DNA Interactions underlying the Phosphorylation-Dependent Regulation of Ets1 Target Gene Expressions[Show abstract] [Hide abstract] ABSTRACT: Cooperative assemblies of transcription factors (TFs) on target gene enhancers coordinate cell proliferation, fate specification, and differentiation through precise and complicated transcriptional mechanisms. Chemical modifications, such as phosphorylation, of TFs induced by cell signaling further modulate the dynamic cooperativity of TFs. In this study, we found that various Ets1-containing TF-DNA complexes respond differently to calcium-induced phosphorylation of Ets1, which is known to inhibit Ets1-DNA binding. Crystallographic analysis of a complex comprising Ets1, Runx1, and CBFβ at the TCRα enhancer revealed that Ets1 acquires robust binding stability in the Runx1 and DNA-complexed state, via allosteric mechanisms. This allows phosphorylated Ets1 to be retained at the TCRα enhancer with Runx1, in contrast to other Ets1 target gene enhancers including mb-1 and stromelysin-1. This study provides a structure-based model for cell-signaling-dependent regulation of target genes, mediated via chemical modification of TFs.
Article: Missense mutations in the DNA-binding/dimerization domain of NFIX cause Sotos-like features[Show abstract] [Hide abstract] ABSTRACT: Sotos syndrome is characterized by prenatal and postnatal overgrowth, characteristic craniofacial features and mental retardation. Haploinsufficiency of NSD1 causes Sotos syndrome. Recently, two microdeletions encompassing Nuclear Factor I-X (NFIX) and a nonsense mutation in NFIX have been found in three individuals with Sotos-like overgrowth features, suggesting possible involvements of NFIX abnormalities in Sotos-like features. Interestingly, seven frameshift and two splice site mutations in NFIX have also been found in nine individuals with Marshall-Smith syndrome. In this study, 48 individuals who were suspected as Sotos syndrome but showing no NSD1 abnormalities were examined for NFIX mutations by high-resolution melt analysis. We identified two heterozygous missense mutations in the DNA-binding/dimerization domain of the NFIX protein. Both mutations occurred at evolutionally conserved amino acids. The c.179T>C (p.Leu60Pro) mutation occurred de novo and the c.362G>C (p.Arg121Pro) mutation was inherited from possibly affected mother. Both mutations were absent in 250 healthy Japanese controls. Our study revealed that missense mutations in NFIX were able to cause Sotos-like features. Mutations in DNA-binding/dimerization domain of NFIX protein also suggest that the transcriptional regulation is abnormally fluctuated because of NFIX abnormalities. In individuals with Sotos-like features unrelated to NSD1 changes, genetic testing of NFIX should be considered.
Article: Mutations in POLR3A and POLR3B encoding RNA Polymerase III subunits cause an autosomal-recessive hypomyelinating leukoencephalopathy[Show abstract] [Hide abstract] ABSTRACT: Congenital hypomyelinating disorders are a heterogeneous group of inherited leukoencephalopathies characterized by abnormal myelin formation. We have recently reported a hypomyelinating syndrome characterized by diffuse cerebral hypomyelination with cerebellar atrophy and hypoplasia of the corpus callosum (HCAHC). We performed whole-exome sequencing of three unrelated individuals with HCAHC and identified compound heterozygous mutations in POLR3B in two individuals. The mutations include a nonsense mutation, a splice-site mutation, and two missense mutations at evolutionally conserved amino acids. Using reverse transcription-PCR and sequencing, we demonstrated that the splice-site mutation caused deletion of exon 18 from POLR3B mRNA and that the transcript harboring the nonsense mutation underwent nonsense-mediated mRNA decay. We also identified compound heterozygous missense mutations in POLR3A in the remaining individual. POLR3A and POLR3B encode the largest and second largest subunits of RNA Polymerase III (Pol III), RPC1 and RPC2, respectively. RPC1 and RPC2 together form the active center of the polymerase and contribute to the catalytic activity of the polymerase. Pol III is involved in the transcription of small noncoding RNAs, such as 5S ribosomal RNA and all transfer RNAs (tRNA). We hypothesize that perturbation of Pol III target transcription, especially of tRNAs, could be a common pathological mechanism underlying POLR3A and POLR3B mutations.
Article: Rational Approach to the Synthesis, Evaluation, and 68 Ga Labeling of a Novel 4-Anilinoquinoline Epidermal Growth Factor Receptor Inhibitor as a New Imaging Agent That Selectively Targets the Epidermal Growth Factor Receptor Tyrosine Kinase[Show abstract] [Hide abstract] ABSTRACT: Certain small-molecule inhibitors that target epidermal growth factor receptor (EGFR), such as Gefitinib, Erlotinib, and Lapatinib, provide a new approach for cancer treatment. In accordance with the pharmacophore model for inhibitor competition at EGFR-binding site, this study proposes a rationalized design for a novel 4-anilinoquinoline EGFR tyrosine kinase inhibitor, [6,7-dimethoxyethoxy]-quinolin-4-yl]-(3-ethynylphenyl)-amine (YCU07). This is the first study to apply ring-closing metathesis toward synthesis of the quinoline nucleus for this 4-anilinoquinoline EGFR inhibitor. YCU07 expressed significant inhibitory activity for EGFR tyrosine kinase in A431 cells, as confirmed by an ABTS microwell peroxidase substrate system read colorimetrically at 405 nm. Injection of (68)Ga-labeled glutamic acid polypeptide (GAP)-YCU07 conjugate in nude mice implanted with A431 was imaged by animal PET camera (LabPET8; Gamma Medica-Ideas) and computed tomography (eXplore Locus; GE Healthcare), to evaluate its biodistribution. (68)Ga-GAP-YCU accumulated in the receptor-positive tumors, with uptake values of 1.50% +/- 0.09% and 2.36% +/- 0.36% of injected activity per gram tissue at 30 and 90 minutes, respectively.
Article: Dominant-Negative Mutations in α-II Spectrin Cause West Syndrome with Severe Cerebral Hypomyelination, Spastic Quadriplegia, and Developmental Delay[Show abstract] [Hide abstract] ABSTRACT: A de novo 9q33.3-q34.11 microdeletion involving STXBP1 has been found in one of four individuals (group A) with early-onset West syndrome, severe hypomyelination, poor visual attention, and developmental delay. Although haploinsufficiency of STXBP1 was involved in early infantile epileptic encephalopathy in a previous different cohort study (group B), no mutations of STXBP1 were found in two of the remaining three subjects of group A (one was unavailable). We assumed that another gene within the deletion might contribute to the phenotype of group A. SPTAN1 encoding alpha-II spectrin, which is essential for proper myelination in zebrafish, turned out to be deleted. In two subjects, an in-frame 3 bp deletion and a 6 bp duplication in SPTAN1 were found at the initial nucleation site of the alpha/beta spectrin heterodimer. SPTAN1 was further screened in six unrelated individuals with WS and hypomyelination, but no mutations were found. Recombinant mutant (mut) and wild-type (WT) alpha-II spectrin could assemble heterodimers with beta-II spectrin, but alpha-II (mut)/beta-II spectrin heterodimers were thermolabile compared with the alpha-II (WT)/beta-II heterodimers. Transient expression in mouse cortical neurons revealed aggregation of alpha-II (mut)/beta-II and alpha-II (mut)/beta-III spectrin heterodimers, which was also observed in lymphoblastoid cells from two subjects with in-frame mutations. Clustering of ankyrinG and voltage-gated sodium channels at axon initial segment (AIS) was disturbed in relation to the aggregates, together with an elevated action potential threshold. These findings suggest that pathological aggregation of alpha/beta spectrin heterodimers and abnormal AIS integrity resulting from SPTAN1 mutations were involved in pathogenesis of infantile epilepsy.
Article: The 8th and 9th tandem spectrin-like repeats of utrophin cooperatively form a functional unit to interact with polarity-regulating kinase PAR-1b[Show abstract] [Hide abstract] ABSTRACT: Utrophin is a widely expressed paralogue of dystrophin, the protein responsible for Duchenne muscular dystrophy. Utrophin is a large spectrin-like protein whose C-terminal domain mediates anchorage to a laminin receptor, dystroglycan (DG). The rod domain, composed of 22 spectrin-like repeats, connects the N-terminal actin-binding domain and the C-terminal DG binding domain, and thus mediates molecular linkage between intracellular F-actin and extracellular basement membrane. Previously, we demonstrated that a cell polarity-regulating kinase, PAR-1b, interacts with the utrophin-DG complex, and positively regulates the interaction between utrophin and DG. In this study, we demonstrate that the 8th and 9th spectrin-like repeats (R8 and R9) of utrophin cooperatively form a PAR-1b-interacting domain, and that Ser1258 within R9 is specifically phosphorylated by PAR-1b. Substitution of Ser1258 to alanine reduces the interaction between utrophin and DG, suggesting that the Ser1258 phosphorylation contributes to the stabilization of the utrophin-DG complex. Interestingly, PAR-1b also binds and phosphorylates R8-9 of dystrophin, and colocalizes with dystrophin at the skeletal muscle membrane. These results reveal a novel function of the rod domain of utrophin beyond that of a passive structural linker connecting the N- and C-terminal domain.
Conference Paper: CLINICAL SPECTRUM OF OHTAHARA SYNDROME CAUSED BY STXBP1 MUTATION
Article: De novo mutations in the gene encoding STXBP1 (MUNC18-1) cause early infantile epileptic encephalopathy[Show abstract] [Hide abstract] ABSTRACT: Early infantile epileptic encephalopathy with suppression-burst (EIEE), also known as Ohtahara syndrome, is one of the most severe and earliest forms of epilepsy. Using array-based comparative genomic hybridization, we found a de novo 2.0-Mb microdeletion at 9q33.3-q34.11 in a girl with EIEE. Mutation analysis of candidate genes mapped to the deletion revealed that four unrelated individuals with EIEE had heterozygous missense mutations in the gene encoding syntaxin binding protein 1 (STXBP1). STXBP1 (also known as MUNC18-1) is an evolutionally conserved neuronal Sec1/Munc-18 (SM) protein that is essential in synaptic vesicle release in several species. Circular dichroism melting experiments revealed that a mutant form of the protein was significantly thermolabile compared to wild type. Furthermore, binding of the mutant protein to syntaxin was impaired. These findings suggest that haploinsufficiency of STXBP1 causes EIEE.
Article: X-ray crystallographic analysis of Runx1-CBFβ-Ets1DNA complex assembled on the enhancer of T cell receptor alpha chain gene


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Grill delicious hamburgers for hungry hordes of people in MadBurger 4! Prove your expertise as a chef by crafting bigger and better burgers for your loyal customers. Cook with fresh, tasty ingredients and follow unique recipes. Never skimp on toppings!
Mad Burger 4 is a highly anticipated online game which will be coming soon to this gaming portal. This game will be completely free to play here at poki.com/en. We will make sure Mad Burger 4 can be found here immediately when it is launched. In the meantime, check out our other 503 Cooking Games, which are rated 95% on average by 170.144 players. Or maybe try out one of our Kids Games, Two player Games or Friv Games.
We changed Gamepilot.com to Poki. Why? Because it's short, recognisable and allows us to have the same name in over 29 different languages. We hope you like it too! Don't worry, you can still type in Gamepilot.com in your address bar if it's easier for you, and you will end up here.
By the way, did you know you can play Poki games on your PC, but also on your tablet and smartphone? Go to Poki.com/en on your mobile device. Give it a try!

subset: commoncrawl


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Job Overview
USAID is an independent Federal Government agency that receives overall foreign policy guidance from the Secretary of State. With headquarters in Washington, D.C., USAID fosters transformational development around the world. Our work supports economic growth and trade; agriculture and the environment; education and training; democracy and governance; global health; global partnerships and humanitarian assistance.
For more information about USAID, visit http://www.usaid.gov.
This position is located within the Office of Human Resources (OHR), Center of Performance Excellence.
The position serves as a Human Resources Specialist (Awards) performing Performance Management functions including performance management policy development, review and oversight. The incumbent serves as a focal point of contact for the Agency's Awards Program, providing award and recognition program advice and guidance. The incumbent receives directions and reports to the Division Chief, Center of Performance Excellence.
As a Human Resources Specialist, you will:
- Provide managers and employees with information on and interpretation of agency's award and recognition policies, procedures, and guidelines.
- Perform the review of award recommendations for compliance with OPM, USAID, and installation instructions and guidelines.
- Ensure that performance documentation required for performance awards are in line with the assigned duties and the official performance plans, mid-year reviews, and annual performance evaluations.
- Establishe long and short-term objectives that focus on identified needs of the organization; and assist in developing plans-of-action to attain established program goals and priorities.
- Provide management advisory services in coaching, counseling, recognizing top performers, and taking appropriate actions on performance issues.
- Collaborate with installation or organization managers and other Human Resource specialists to develop, review, and analyze a wide range of modified, new, or proposed performance management instructions, guidelines, opinions, and decisions as it pertains to agency awards.


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Colorectal cancer in a first-degree relative increases one's personal risk of the disease, but the relationship of family history to cancer recurrence and survival is uncertain. Chan and colleagues Article assessed disease-free survival, recurrence-free survival, and overall survival in a prospective study of patients with stage III colon cancer who were enrolled in a randomized trial of adjuvant chemotherapy. The authors found that among patients with stage III disease and receiving adjuvant chemotherapy, a family history of colorectal cancer was associated with a significant reduction in cancer recurrence and death. In an editorial, Pasche Article discusses the molecular genetics of colorectal cancer.
Graphic Jump Location
Low levels of high-density lipoprotein cholesterol (HDL-C) are associated with an increased risk of ischemic heart disease, but whether this is a causal effect is not clear. In analyses of data from 2 general population studies and 1 case-control study of ischemic heart disease in Copenhagen, Denmark, Frikke-Schmidt and colleagues assessed whether low levels of HDL-C concentration caused by inherited loss of function mutations in the ABCA1 gene are associated with an increased risk of ischemic heart disease. In comparisons with noncarriers of the mutations, the authors found no association between low levels of HDL-C due to heterozygosity for the mutations and increased ischemic heart disease risk.
Symptomatic heart failure is associated with a median life expectancy of less than 5 years. Whether patients with heart failure understand their prognosis is not clear. Allen and colleagues Article interviewed 122 ambulatory patients with heart failure to assess patients' expectations of survival and compared these with life expectancies calculated using a validated disease-specific model. The authors found that a majority of patients substantially overestimated their remaining life span compared with model-based predictions (median, 13.0 years vs 10.0 years, respectively). In an editorial, Yancy Article discusses the accuracy of tools to predict prognosis in chronic heart failure and considers the benefits and risks of sharing this information with patients.
Randomized clinical trials (RCTs) of diabetes interventions often examine physiological or laboratory outcomes rather than patient-important outcomes, such as death and quality of life (morbidity, pain, function). To determine the extent to which ongoing and future RCTs in diabetes will ascertain patient-important outcomes, Gandhi and colleagues searched 3 RCT registries in November 2007, identified phase 2 through 4 RCTs actively enrolling patients, and randomly sampled 50% for review. Of the 436 trials reviewed, the authors found that only 18% of ongoing RCTs in diabetes have outcomes that patients consider important as primary end points.
Mrs T has type 2 diabetes, chronic hypertension, and a history of gastric bypass surgery, and she is contemplating pregnancy. Coustan discusses the management of diabetes prior to and during pregnancy and discusses the risks and benefits of preconception gastric bypass surgery for a woman with type 2 diabetes.
"[A]s my friend Bonnie taught me, carrying this metaphor to every affected individual can be counterproductive, inappropriate, even destructive." From "Waging Peace in the War on Cancer."
Congress has passed the Genetic Information Nondiscrimination Act, which bans insurers and employers from using genetic information to determine health coverage and to make hiring, firing, and other employment-related decisions.
Presidential health and the public's need to know
Legal barriers to health system reform
Join Wendie Berg, MD, PhD, June 18 from 2 to 3 PM eastern time to discuss screening women at high risk of breast cancer with mammography plus ultrasound vs mammography alone. To register, go to http://www.ihi.org/AuthorintheRoom.
Dr DeAngelis summarizes and comments on this week's issue. Go to http://jama.ama-assn.org/misc/audiocommentary.dtl.
How would you manage a 70-year-old man with severe coronary and peripheral artery disease who presents with acute-onset slurred speech and left facial droop? Go to www.jama.com, read the case, and submit your response, which may be selected for online publication. Submission deadline is June 25.
For your patients: Information about pregnancy and diabetes.
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text: True or false? (a) The Raman shift of a given Raman spectral line does not change if the frequency N0 of the incident radiation is changed. (b) Stokes lines have positive Raman shifts. (c) The selection rules for pure-rotational Raman transitions are the same as for ordinary pure-rotational absorption transitions. (d) A molecule with no electric dipole moment will not show a pure-rotational absorption spectrum but may have pure-rotational lines in its Raman spectrum. (e) Every molecule has a vibrational Raman spectrum. (f) In vibrational Raman spectra, Stokes lines are more intense than anti-Stokes lines. (g) A normal mode that is IR-inactive must be Raman-active.


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Ruth Soukup: Unstuffed
New York Times bestselling Author, Ruth Soukup, shares her personal story on how she took back her life.
2583 results for '700clubi'. Showing results 109 - 126
New York Times bestselling Author, Ruth Soukup, shares her personal story on how she took back her life.
The Benham brothers share how to thrive like Daniel in modern-day Babylon.
Brothers Jason and David Benham discuss their latest book, "Living Among Lions."
Military kids face the challenges of frequent moves, parents deployed, visible and invisible injuries, and emotional trauma from a...
A radio host hears the voice of God – from the mouth of her four-year-old daughter.
Show children they are important. Rewrite their fatherless story through mentoring.
An Olympic hopeful wins something better than gold.
The Mentoring Project is a national organization seeking to rewrite the fatherless story through mentoring. In Oklahoma City they...
How to speak "Christianese" and other fun (and odd) things about our Christian subculture.
Kegan Wesley is molested at a young age by several men, leads an LGBT lifestyle for many years, until...
A couple wanted more than anything to have children, but neither could. Hear the miraculous answer to prayers.
Anne Graham Lotz shares how the Daniel prayer can move mountains and change nations.
Anne Graham Lotz shares how the Daniel prayer can bring change to the nations.
A mother pleads for her dying son. Watch how he gets a second chance.
700 Club Interactive's Andrew Knox offers a reflection on our real enemy in the aftermath of the Orlando terrorist...
Dolly Parton opens up about her remarkable journey to fame.
Hear why fathers are an important part of God's plan as we celebrate Father's Day.
Paralyzed after a diving accident in 2011, Cameron Horner discusses his faith in overcoming challenges and the new movie,...


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BIG is a community owned and run charitable organisation based in south Edinburgh. Our mission is to renovate Bridgend Farmhouse to create a centre for Learning, Eating and Exercise. This will provide a community hub along with a variety of activities and services enabling people to live healthier, happier lives and have better relationships with the world around them.
Since winter 2014 we have had a licence to use the building and have been working hard to bring it back to life. Find out more about our project and how you can get involved as you explore our website.


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Shared publicly -
Katelyn Kinneycommented on a video on YouTube.
I love this video! I haven't seen something like this before and I follow A LOT of beauty youtubers. I also liked your video about taking off makeup around a boy. It was not just a typical tutorial or favorites video. Keep being awesome. Also I know a lot of youtubers put bloopers at the end of their videos and it's hilarious. Maybe you could consider doing the same because you're quite funny. It might help followers feel like they're getting to know you better. I love you and have for years! So thanks for sharing a part of your life with me. <3


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Hi, Filipe N
thank you very much for visit to my gallery and Like + Fav! :)
have a nice day for you.
best wishes liem ailie
Hi, Julie
very beautiful capture ♥ + ☆
best regard liem ailie
Wonderful view of this charming town!!! Nice perspective:). Good work. Best regards Soyvind1982
Beautiful photo, L+F
Perfect Picture, a very rare sight.
Best regards from Upperaustria
Very nice natural frame & successful shot. I Like it a lot!
Impressive work! - Like Best regards from Athens
Wowwww ! – This is a great shot! – L & FV. My best regards.
Hi, Si Mulgrave


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New laws to take effect at start of New Year
Almost two dozen new state statutes will take effect at the start of the new year. Some are arcane or technical changes to existing laws while others are more sweeping. The new statutes will:
—Increase the minimum auto insurance liability coverage required for drivers, boosting boost costs for motorists who carry only the minimum.
—Impose a 2 percent fee on packages of prepaid cell phone minutes, with revenue to go to statewide improvements to 911 systems.
—Prohibit the sale of novelty cigarette lighters, with exceptions for lighters manufactured before 1980, those considered collectibles and devices designed to ignite grills or fireplaces. Violators could be fined up to $250.
—Create a public safety campaign to warn Louisianians about alleged risks of consuming Chinese seafood, even if it is deemed safe by the state's seafood inspection program.
—Require school boards to ensure that children in foster care can remain enrolled in the same public schools in which they were enrolled when entering foster care, if that is determined to be in the children's best interest.
—Require the Department of Social Services to conduct background checks of potential employees who will investigate child abuse or neglect, supervise children or perform licensing surveys of child care facilities.
—Transfer the responsibility for regulating ground water resource management, water wells and water well drillers from the Department of Transportation and Development to the Department of Natural Resources.


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Receipt of Test Data Under the Toxic Substances Control Act
This Notice document was issued by the Environmental Protection Agency (EPA)
For related information, Open Docket Folder
Receipt of Test Data Under the Toxic Substances Control Act
Environmental Protection Agency (EPA).
EPA is announcing its receipt of test data submitted pursuant to a test rule issued by EPA under the Toxic Substances Control Act (TSCA). As required by TSCA, this document identifies each chemical substance and/or mixture for which test data have been received; the uses or intended uses of such chemical substance and/or mixture; and describes the nature of the test data received. Each chemical substance and/or mixture related to this announcement is identified in Unit I. under SUPPLEMENTARY INFORMATION.
For Further Information Contact
For technical information contact: Kathy Calvo, Chemical Control Division (7405M), Office of Pollution Prevention and Toxics, Environmental Protection Agency, 1200 Pennsylvania Ave. NW., Washington, DC 20460-0001; telephone number: (202) 564-8089; email address: .
For general information contact: The TSCA-Hotline, ABVI-Goodwill, 422 South Clinton Ave., Rochester, NY 14620; telephone number: (202) 554-1404; email address: .
Supplementary Information
I. Chemical Substances and/or Mixtures
Information about the following chemical substances and/or mixtures is provided in Unit IV.: D-gluco-heptonic acid, monosodium salt, (2.xi.)-(CAS No. 31138-65-5).
II. Authority
Section 4(d) of TSCA (15 U.S.C. 2603(d)) requires EPA to publish a notice in the Federal Register reporting the receipt of test data submitted pursuant to test rules promulgated under TSCA section 4 (15 U.S.C. 2603).
III. Docket Information
A docket, identified by the docket identification (ID) number EPA-HQ-OPPT-2013-0677, has been established for this Federal Register document that announces the receipt of data. The test data received have been added to the docket for the TSCA section 4 test rule that required the test data. Use the document ID number provided in Unit IV. to access the test data in the docket for the related TSCA section 4 test rule.
The docket for this Federal Register document and the docket for each related TSCA section 4 test rule is available electronically at or in person at the Office of Pollution Prevention and Toxics Docket (OPPT Docket), Environmental Protection Agency Docket Center (EPA/DC), West William Jefferson Clinton Bldg., Rm. 3334, 1301 Constitution Ave. NW., Washington, DC. The Public Reading Room is open from 8:30 a.m. to 4:30 p.m., Monday through Friday, excluding legal holidays. The telephone number for the Public Reading Room is (202) 566-1744, and the telephone number for the OPPT Docket is (202) 566-0280. Please review the visitor instructions and additional information about the docket available at .
IV. Test Data Received
This unit contains the information required by TSCA section 4(d) for the test data D-gluco-heptonic acid, monosodium salt, (2.xi.) (CAS No. 31138-65-5)
1. Chemical Use(s): Organic salt used as a chelating agent in cosmetics, dairy cleaners, bottle cleaners, food contact paper and paperboard, manufacturing, metal cleaning, kier boiling, caustic boil-off, paint stripping, boiler water additive for food processing, and as an ingredient in aluminum etchant. This chemical is also used as a sequestrant, latex stabilizer, and in intravenous pharmaceuticals.
2. Applicable Test Rule: Chemical testing requirements for second group of high production volume chemicals (HPV2), 40 CFR 799.5087.
3. Test Data Received: The following listing describes the nature of the test data received. The test data have been added to the docket for the applicable TSCA section 4 test rule and can be found by referencing the document ID numbers provided. EPA reviews of test data will be added to the same docket upon completion.
Health Effect. Combined Repeat Dose Toxicity with Reproduction/Developmental Toxicity Screening Test. The document ID number assigned to this data is EPA-HQ-OPPT-2007-0531-0790.
List of Subjects
Environmental protection, Hazardous substances, Reporting and recordkeeping requirements.
Dated: June 10, 2014.
Maria J. Doa,
Director, Chemical Control Division, Office of Pollution Prevention and Toxics.
[FR Doc. 2014-14245 Filed 6-17-14; 8:45 am]
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Date Posted: Jun 18, 2014
Federal Register Number: 2014-14245
Comments Received*
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* This count refers to the total comment/submissions received on this document, as of 11:59 PM yesterday. Note: Agencies review all submissions, however some agencies may choose to redact, or withhold, certain submissions (or portions thereof) such as those containing private or proprietary information, inappropriate language, or duplicate/near duplicate examples of a mass-mail campaign. This can result in discrepancies between this count and those displayed when conducting searches on the Public Submission document type. For specific information about an agency's public submission policy, refer to its website or the Federal Register document.
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How to Make Metal Rust
Four Methods:Acid and Copper SolutionVinegar and BleachPeroxide and SaltVinegar and PeroxideCommunity Q&A
Whether you are doing a science experiment, using rusted metal in an art piece, or simply want to try rusting something, causing metal to rust is very simple with the right solutions. Various methods are provided here for you to choose from.
Method 1
Acid and Copper Solution
1Ensure that the metal you are working with will rust. Only metals containing iron will rust, and some iron alloys will rust slowly or not at all. Stainless steel, an alloy of iron and chromium, will be very difficult to rust. Cast iron or wrought iron will rust most easily.
2Measure some hydrochloric acid into a plastic bottle. Hydrochloric acid is readily available in low concentrations at hardware stores, often labeled as muriatic acid. Handling it carefully, pour about 2 ounces (60 ml) into a sturdy plastic bottle. You should wear rubber gloves and safety glasses when doing this.[1]
3Dissolve a bit of copper in the hydrochloric acid. Dissolving copper into the acid solution creates a wash that will speed the rusting process. The best way to dissolve copper in the acid is to wrap a short length of copper wire into a coil and submerge it in the acid for about a week.
- When leaving the copper to soak, do not cap the bottle tightly. The gases produced during the chemical reaction will cause pressure to build inside the bottle. Also, make sure to clearly label the bottle and store it out of reach of children or pets.
- Copper coins can be used as well. Make sure the coin's content is largely copper; for instance, United States pennies made after 1982 are only 2.5 percent copper. However, pennies made before 1982 are 95 percent copper.
4Dilute the copper and acid solution with water. After some of the copper has dissolved into the acid, put on protective gloves and carefully remove the the copper from the solution. Once you have taken it out of the solution, you can discard it. Dilute the acid with water in a ratio of roughly 1 part acid to 50 parts water. If you used 2 ounces (60 ml) of hydrochloric acid, you should mix it with about a gallon (3.8 L) of water.[2]
5Clean your steel or iron thoroughly. The acid and copper solution will work best when the metal is very clean. There are commercially available products designed for cleaning scale or corrosion from metal, but a wash and rinse with soap and water will generally be sufficient.
6Apply the acid solution. Apply a light layer of the solution to the metal and allow it to air dry. The acid can be applied with a spray bottle or paint brush, although the acid will quickly deteriorate any metal components of the spray bottle. Wear protective gloves and safety glasses when applying the acid solution, and work in a well-ventilated area, preferably outdoors.
7Allow the metal to rust. Within an hour, you should see noticeable rusting on the metal. You do not need to wipe or rinse away the acid wash; it will dissipate naturally. If you desire a heavier layer of rust, apply another wash of the acid solution.
Method 2
Vinegar and Bleach
1Check to make sure that your metal has no finish or sealer on it. This method works best on tin or iron items. Once inspected, mix one part vinegar with two parts bleach in a large plastic container. The amount you use should be determined by the size of the item you are hoping to rust.[3]
2Place your metal into the container. Make sure that it is fully submerged, unless you only want a section of your metal rusted. Let the metal rest in the solution for approximately thirty minutes. During this time, the metal will take on a nice crunchy rust cover.
3Dry your pieces off with paper towels. You can also dry them off with regular towels if you don't care about staining them. As a side note, if you use paper towels, you will get very cool rusted-looking paper towels out of the drying process. Dispose of the vinegar-bleach mixture by pouring it down the drain.[4]
4Wait until the items are fully dry before doing anything with them. You want to make sure that the item is fully dry before handling them so that you do not expose your skin to too much bleach. When it has dried, rub the rust off to whatever degree you prefer. Some people prefer their rust thick, while others prefer an eroded look.
5Use a spray finish to seal the rust onto the piece. In general, a matte spray sealer works well when sealing up rust on an item. You can purchase these sort of sprays at your local home improvement store.
Method 3
Peroxide and Salt
1Select a well-ventilated area to work in. Peroxide can be dangerous if too much is inhaled at a time. Choose a piece of metal that is either iron or tin--both will work with this method.
2Transfer the peroxide to a spray bottle. The spray bottle will make it much easier to apply to your metal. Spray your piece of metal with a sizeable amount of peroxide. Spraying more peroxide will help to speed up the rusting process.[5]
3Sprinkle salt onto the piece of metal. You should do this while the peroxide is still wet. The rusting process will begin almost immediately and is actually easy to see. You can pour on more or less salt depending on how thick or crusty you want the rust to be.[6]
4Let the metal piece air dry. Unlike the bleach and vinegar method, you should let your metal air dry. If you wipe of the salt while the peroxide is still wet, you will disrupt the rusting process and cause your rust to come out blotchy. Once dry, rub the salt off and admire your work.
5Experiment with this method. While you have just read about the basic way you can use peroxide and salt to cause metal to rust, the sky is really the limit when it comes to this technique. Rub the salt off and then spray the piece with peroxide again. Try different amounts of salt or dip your metal into water once it has dried. The water will give the rust a smoother texture.
Method 4
Vinegar and Peroxide
Community Q&A
Which method should I use if I have an old car that I want to look or be completely rusted?wikiHow ContributorGrind all the paint off and make sure you do right down past any galvanizing to reveal the bare metal. Rub beer and salt into the panels, leave for two to three hours then remove with hot water. You will see rust almost immediately.
Will any or these methods work on a new galvanized bucket?
Can you use a brush while using this method and not affect the painted areas?
Is there a way to do this without using vinegar?
How do I speed up the rust process on a model car?
- Always exercise caution when working with hydrochloric acid, bleach, or peroxide. Even in low concentrations, these chemicals can cause skin and mucous membrane irritation.
Things You'll Need
Acid and Copper Method
- Iron or iron alloy
- Rubber gloves
- Safety glasses
- Hydrochloric acid
- Measuring spoon
- Plastic bottle
- Copper wire
- Gallon jug
- Water
- Soap
- Cloth
- Spray bottle or paint brush
Bleach and Vinegar Method
- Household bleach
- Vinegar
- Plastic mixing container
- Paper towels
Peroxide and Salt Method
- Hydrogen peroxide
- Table salt
- Spray bottle
Sources and Citations
- ↑ http://metalgeek.com/archives/2006/06/13/000065.php
- ↑ http://metalgeek.com/archives/2006/06/13/000065.php
- ↑ http://gomakesomething.com/ht/age/rust-guide/
- ↑ http://www.cleaninginstitute.org/sustainability/some_facts_about_.aspx
- ↑ http://www.lucydesignsonline.com/2013/08/how-i-give-metal-and-wire-pieces-aged.html
- ↑ http://gomakesomething.com/ht/age/rust-guide/
Article Info
Categories: Metalwork and Wire Projects
In other languages:
Português: Fazer Metal Enferrujar, Español: oxidar metal, Italiano: Fare Arrugginire il Metallo, Français: faire rouiller du métal, 中文: 使金属生锈, Русский: заржавить металл, Deutsch: Metall zum Rosten bringen, Bahasa Indonesia: Membuat Logam Berkarat, Nederlands: Metaal laten roesten
Thanks to all authors for creating a page that has been read 350,303 times.


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Sandra Bertram Meier
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NOTE: I have been given management of work created by dee (inactive) for the Klein Memorial Cemeteries. Contact me with any edits.
Researching and documenting my family history is one of the most important works of my life. While looking for my family - I photo cemeteries to be able to help others. I feel everyone should know as much about their ancestors as possible. Through my research I have been able to spend quality time with my sister, Janet Bertram and my mother, Norma Davidson Bertram.(Mother passed away on April 6, 2013 and we really miss her helping). We travel the great state of Texas visiting ancestors graves and photo documenting as much as possible. Findagrave is a wonderful place that has brought lots of people into my life I would never have known otherwise. I like filling photo requests when possible. We need to all keep up the good work. Thanks to all who are working so hard.
After experiencing a vulgar language email from an East Texas Grandma after denying a transfer request - I find it necessay to add the following statement. Find a Grave has guidelines for this site. I will follow those guidelines from this point on. "Transfer requests must follow Find A Grave guidelines. Be specific on your relationship. Must be the four generations as listed in the rules. I will make corrections, additions, & family links when asked. Use the Edit tab, then the Suggest A Correction option & include your email address."
My photos may be used for family trees, but please ask first. I have found many of my photos on a Find A Grave members Ancestry.com file with no credit or permission being given. Please read the rules for photo use in the Find A Grave help. Many hours are spent taking photos and the photographer should be given credit.
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deanna french
Newton Co. photo George Gee
I am a Vermont Civil War uff, and am presently working on a project to identify the last resting places of many of our "Old Soldiers. George Gee is one such patriot. May I use the photo you contributed to his F.A.G Memorial, to post on the Vt. C.W.site?( www.vermontcivilwar.org)
You would receive credit for this.
Thank you for your consideration.
Deanna French
Added by
deanna french
on Aug 14, 2016 4:26 PM
Jo Anne Russell
RE: William Martin
Thank you for your prompt response. It's done -- I created a memorial for Mary Elena Thomas with links to her parents and spouse, William Alexander Martin, and sent edit suggestions to the other two contributors.
Added by
Jo Anne Russell
on Aug 02, 2016 5:57 PM
john lanier
Sarah Margaret Breland
Sandra, I am a grandson of Sarah Margaret Breland (#102822198). I noticed on this page that it indicates she has a daughter named Sarah Margaret Breland that is also buried in this cemetery. The individual indicated as her daughter, Sarah Margaret Breland) is in actuality her niece. The niece, Sarah Margaret Breland, is the daughter of Clayton Caldwell Breland (#66250424) and Myrtle Breland (#6650424). Clayton Caldwell Breland is the son of Sarah Margaret Breland (#102822198)
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john lanier
on Aug 01, 2016 1:37 PM
Tom Streetman
Thanks for all the updates you've done so far. I'm working on my William Nelson Williams line this week and may have a few more update requests headed your way since you seem to manage most of Denson Cemetery entries that I am interested in.
Have a good weekend!
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Tom Streetman
on Jul 15, 2016 3:57 PM
Edit Request
Thank you for catching the double posting for Frank Allen Crorey, Sr Memorial# 116514942.
I have updated the original as suggested Memorial# 77114044.
I've transfer your grave site pics as well. Thanks for that as well!
Peace & be well!
Added by
on Jul 12, 2016 8:01 PM
Amy MRA
Memorial Edit Request
I noticed that on the record for Robert Smith Owen (#97734667) it says date of death is in March, when actually it is in May.
Added by
Amy MRA
on May 30, 2016 11:28 AM
Sherri Harris
RE: Aunt Georgia
Ok, well thanks for your help.
Georgianne was my father's sister. He is her only living sibling. It does show her as being her own sibling??
Added by
Sherri Harris
on May 15, 2016 7:56 PM
Robert W Beck Grave at Buck Foster Cemetery
Robert Walter Beck is my dad and he is buried at Buck Foster Cemetery in Huntsville, TX. The search listing for him gave me the correct marker, but his middle name is spelled incorrectly. He is Robert WALTER Beck. I appreciate you correcting that for him. And I appreciate you including him and my mother in your search and photos. I live in Georgia and seeing the cemetery and their markers again is so wonderful.
Thank you,
Added by
on Apr 20, 2016 12:05 PM
4th great grand daughter
F. M. Haynes # 44331085
Please change the name to Francis Marion Haynes,
Death Certificate # 43036
Father: Senie Haynes
Mother: Louisa Williams
Spouse: Irene Haynes
Thank you so much;
Ruthie in Texas
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4th great grand daughter
on Feb 20, 2016 4:46 PM
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Find A Grave Memorial # 44331085
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September 1, 2009, 11:50 AM
I have mounted a number of scopes over the years, and it is always frustrating to true the plane of the reticle to the bore centerline. Why don't rings & scopes come with witness marks to make it easier to mount keeping the reticle level??


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Support the arts and help Theatre Southwest continue to bring you exciting high-quality theatre by donating via Paypal. (Paypal account not required.)
On the third Wednesday of every month we hold a meeting at 8 pm for TSW members and the public. We highlight TSW activities, provide refreshments as well as entertainment with a scene from either the current show or a workshop. Please attend. We would love to see you!
NOW ACCEPTING SUBMISSIONS for The 12th Annual Reader's Theatre
Saturn Returns
by Noah Haidle
Directed by John Mitsakis
An astrological phenomenon presupposes that when the planet Saturn completes its cycle approximately every 30 years, we may be affected by deep trauma and/or change. Saturn Returns follows Gustin Novak, a radiologist living in Grand Rapids, Michigan, at ages 28, 58 and 88. He is inextricably bound to the women in his life: at age 28, his wife, Loretta; at age 58 his daughter, Zephyr; and at age 88, his nurse, Suzanne. Gustin endures as the women come and go, live and die.
Fridays & Saturdays, Sept 9 - Oct 1 at 8 pm
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How far would you go for your child? For Genevra and Joshua Bradley, the question is no longer hypothetical. Their three-year-old son, Mac, is next on the waiting list for Bright Ideas Early Childhood Development Academy—and everyone knows once you're in there, your life will unfold with glorious ease. Josh and Gen are one fatal dinner party away from the ultimate success as parents: The Right Pre-School. You may never look at pre-school—or pesto—the same way again….
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Once in college, I had a friend Google "how to make a grilled cheese," and I remember being completely baffled that someone would need a step-by-step guide to make one of the most basic staples of the american child's diet. I was reminded of this moment a few days ago as I watched Kylie Jenner's series of Snapchat videos ...
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Obama's test: Try to avoid 'mission creep' in Iraq
WASHINGTON -- President Barack Obama, in charting a new phase of American military engagement in Iraq, pledges that his war-weary country will not be "dragged back" into a lengthy conflict or become ensnarled in "mission creep."
But recent U.S. military history is full of warning signs about the difficulty of keeping even a limited mission from expanding and extending. The prospect that this latest mission in Iraq could follow that pattern is particularly risky for Obama, given that he has staked so much of his legacy on having brought America's long war there to a close.
Already some of the White House's closest allies worry that Obama's plan to send in 300 special operations forces to train the Iraqi military could be the first step in pulling the U.S. back into Iraq's violent sectarian fight.
Anna Galland, the executive director of the liberal group MoveOn.org, said even a limited mission "is a dangerous and troubling development that threatens to lead to broader military engagement."
Indeed, the U.S. has seen small operations escalate before.
The conflict in Vietnam started with Presidents Dwight Eisenhower and John F. Kennedy sending limited numbers of military advisers to train and assist local forces. But those numbers increased over time and set the stage for what ultimately became a yearslong combat operation.
The wars that began in Iraq and Afghanistan in the last decade were intended to be combat missions from the start. Few people expected at the time that the Iraq War would drag on for more than eight years, the Afghan conflict for more than a dozen years, or that the U.S. troop presence in each country would peak above 100,000.
Obama acknowledged the risks of mission creep when he outlined plans Thursday to help Iraq combat the Islamic insurgency that has made gains with lighting speed.
The plans mark a sharp shift for a president who oversaw the full withdrawal of American forces from Iraq in late 2011 after Washington and Baghdad failed to reach an agreement to keep a few thousand troops in place.
Administration officials insist Obama does not intend to commit the U.S. to another lengthy war in Iraq or put American forces in combat roles.
But there are few guarantees when it comes to sending Americans into Iraq's unstable security situation. Though the troops are not being sent specifically for combat purposes, all are armed and have the right to defend themselves if they are in danger.


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Top Definition
its an other word for computer
"i am going to play a gmae on my naraka"
Por zergafis 14 de octubre de 2006
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Can you define these popular missing words?
it is a diffrent word for computer.
"i'am going to play a game on my naraka"
Por zergafis 13 de octubre de 2006
The Place of Suffering in Buddhism for thousands of years before Reincarnation.
"I'll be going to Naraka."
Por Ferguson Productions 10 de marzo de 2016


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The "finger family song" is a very popular nursery rhymes that makes learning fun. Tags: family finger, finger family, family finger song, nursery rhymes, finger family song
i know you are but what am i?
Dude, I can't believe you just said the 'n' word.
You're a nice person.
hey baby gurl


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Norpole® 120 lbs. / day Commercial Ice Maker
Item # WX2-226271SOLD OUT
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Norpole® 120 lbs. / day Commercial Ice Maker... high - efficiency, high - output for your back - of - the - house needs!
Whether you're starting a restaurant or smaller coffee house, you'll need to keep the place well-stocked with ice! Enter, the Norpole® Commercial Ice Maker! Perfect for supplying customers with whole cubes in everything from fountain beverages to iced chai... or, crush and chop ice for margaritas or other "frozen" beverages! Uses an advanced water-spray ice-making method with an air-cooled condenser to create up to 120 lbs. of ice per day! Features an incredible self-maintenance system whose micro-computer control facilitates ice-making and flawless error detection.
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- Meets R134a standards for environmental-friendly design
- Made with great-looking 304 stainless steel
- Makes "bullet"-shaped ice pieces
- Measures 21 x 22 x 32 2/3", weighs 110 lbs.
- UL-listed for safety.


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A look at free software and its makers
Free software simulates the population of Mars, which is due to start 30 years from now, gives users an overview of social networks, and keeps the peace at the debating society.
Alexandria Luciano lives on Mars. No, she's not Linux Magazine's latest foreign correspondent, but one of the first settlers on the red planet. Of course, she hasn't landed yet, because this event will not take place until some time after the year 2040. The Mars Sim project gives you a sneak preview.
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Innovative system adds a hard drive and Ubuntu Core to the RPi for an IoT hub.
Linus Torvalds Confirms the Date of the First Linux Release
Linux is two weeks younger than we thought!
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The Apache Software Foundation considers retiring OpenOffice
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Security researchers have already notified Microsoft; some fixes are available
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The company is collaborating with Google and Intel to use Kubernetes as an engine for Fuel
Canonical Joins Document Foundation Advisory Board
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Search Results: 'wormwood society'
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2011 calendar for the Wormwood Society. Photos of absinthe and absinthe related themes by members of the WS.
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Time has left the Earth behind and a renegade group of humans attempted to create a god. They succeeded. Humanity has spread out into the galaxy and turned its back on Earth. Now, the survival... More > of the race depends on what has been grown in fallow fields. A hidden plot has been sown for centuries by the Nephilim. They shaped society, pulling deft strings like master marionettes, seeking the key to their own escape, the key to humanity's evolution into godhood. When their proto-deity appears, it is more then they bargained for. A series of betrayals and a web of intrigue reveals a master plan that will manipulate the evolution of every human in the galaxy. Wormwood is 415,000 words in length and split into four parts. Each part brings the reader closer to the ultimate truth, until finally the secret of Wormwood is revealed. Wormwood represents my first novel series and combines elements from the science fiction and fantasy genres.< Less
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No one wants to get injured, no matter how terrible the loss, or how the incidents happened and cause the suffering. Unfortunately, no one could expect its coming, particularly while you are driving a car. If you are feeling all okay before leaving or even while you are on your way, it does not determine your complete safety in the road. If you are not the one who have to be blamed for a car accident, then the others might be. However, you may not be able to escape from significant loss.
In that case, have you ever thought about hiring a car accident lawyer to be your advocate in stating your rights in the incidents?
Why We Need Such Lawyer
If you think you have enough knowledge of traffic laws, completed with every detail included, then why you need to hire an attorney after being involved in a car accident? We know that attorney got license for their knowledge and legal works, of which their service is legally acknowledged by laws. This, somehow, needed whenever you face severe injuries that involves legal claims from your insurance companies.
It is truly possible for everyone to face some forms of disputes against the laws, especially over the insurance companies, regarding the loss you should endure because of the accident. If you can find words to state the real events and how much your injuries should be covered by the insurance companies, a car accident lawyer is highly needed.
Severe injuries may lead to costly medical bills, and this cannot sometimes be resolved by individuals without advocacy from a car accident lawyer. They may help you forecast possible outcomes of the injuries that may not be seen in short-time period. The long-time cost you should pay for treating your injuries should be carefully analyzed and legally noticed. And those works require a professional.
In short, if you are doubtful of what you know about traffic laws, particularly those applied to accidents, you'd better consult your issues to a car accident lawyer in order to prevent any worse loss happening.
Cost To Pay
Hiring an attorney is sometimes seen as a luxurious decision. It does not cost cheap to get a professional to help you resolve your issues in the street. Therefore, consulting to a car accident attorney seems to be a strange idea, especially when you do not experience terrible injuries or big loss.
However, as mentioned earlier, those with severe injuries, and significant loss may need to consider asking for help from them. Though it would be a bit costly, as long as you know where your money goes, and that it goes to the right place, an attorney is quite helpful. Yet, you need to firstly check on the degree of loss you endure. The more terrible it is, the higher you need to pay your attorney. In that case, a careful analysis on sparing your money between those you possibly get from the insurance and the rest for paying the attorney, is highly necessary.


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On 20/06/07, Mark <markg85 gmail com> wrote:
Could someone add the SVG logo on the wiki there with a transparent background or a png version with a transparent background.
I believe that you can e-amil logo fedoraprejct org (or whatever the e-mail address is on the Logo wiki page) with a request for such a file then they will send it to you. This might be to protect the quality of fedora-derived imagery with the official logo on it. I, personally do not have a SVG with it, either, I just use a self-made crop of it! ./b -- ..// seawolf //.. Ben Arnold e-mail / msn / icq / yahoo iamseawolf (at) gmail (dot) com http://clik.to/seawolfsanctuary fedora core : artwork GnuPG Available - ask me!


text:
Wednesday, September 28, 2016
Rovio's ToonsTV Comes to Apple TV
Rovio Entertainment's kid-friendly ToonsTV video on demand app — which has so far accrued over 5.6 billion views — is now available worldwide through Apple TV in the ... Continue Reading →
Breaking Into The Biz, Part 2
How will you get your start in the animation writing game? Last issue, we spoke to three of Baboon's team of award-winning scribblers, who each got their break using one classic ... Continue Reading →
Ask a Baboon Ask A Baboon – Issue #253
Putting More Spring in Your Springboard, Part 1 Think of your favorite episode of your favorite cartoon… Got it? Well, guess what – the perfect plot, the ingenious jokes: those ... Continue Reading →
Ask A Baboon – Issue #250
Comedy Is When A Bird Hits A Pig … Twice Our writers explore the fine lines between slapstick, ... Continue Reading →
Cake Inks 'Angry Birds' Deal with Rovio
CAKE has entered a distribution deal with Rovio Entertainment to represent its slate of animated content based on the popular Angry Birds brand. Under the agreement, CAKE will rep the ... Continue Reading →
The Animag 250: TV Shows Destined to Be Classics
The Animation Magazine 250th issue celebration continues, this time with our list of TV Shows Destined to be Classics. They are: Adventure Time All Hail King Julien The Amazing World ... Continue Reading →
Silent But Funny
Writing duo discusses the challenges of making people laugh without using dialog on Angry Birds Toons. Comedy is when a bird hits a pig — and Baboons are writing for them both. Yes, ... Continue Reading →
Ask A Baboon – Issue #244
Birth of a Baboon Joe Vitale turns the tables on Mike de Seve and interviews him about his career in animation and how collective became a reality. Mike de Seve From Beavis and Butt-Head ... Continue Reading →
'Angry Birds' Movie Flies to SPI Vancouver
Rovio Entertainment has chosen Sony Pictures Imageworks in Vancouver as its primary animation house for the production of the Angry Birds movie, the upcoming animated film based on ... Continue Reading →
Calabash Animates 'Angry Birds' Game Ad
Calabash Animation has bought to life Rovio's iconic Angry Birds for a 30-second spot for the brand's Pirate Pig Attack board game. Created via the Uproar! Agency in New ... Continue Reading →


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Bens Focus
17 July 2013, 13.36 | Posted in apparel, Art, Sneakers | 1 comment »
We recently came across Bens Focus on Instagram, a Portland based illustrator, herbal connoisseur and sticker fiend who does everything from wine bottles to hand drawn t-shirts to custom kicks. We like what he's doing. Check the detail on the t above and his white Levi's and Vans Canvas Authentics after the jump.
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Alice Hoffman
News about Alice Hoffman, including commentary and archival articles published in The New York Times.
'The Marriage of Opposites,' by Alice Hoffman
A novel inspired by the painter Camille Pissarro's parents.
August 16, 2015, Sunday
MORE ON ALICE HOFFMAN AND: Books and Literature , Hoffman, Alice , Pissarro, Camille , The Marriage of Opposites (Book)
Alice Hoffman's 'Nightbird'
In Alice Hoffman's novel, a friendship forms when two girls investigate a witch's curse.
April 12, 2015, Sunday
Review: 'The Dovekeepers,' a CBS Mini-Series Starring Cote de Pablo
This two-part movie is based on Alice Hoffman's fictional account of the siege of Masada.
March 30, 2015, Monday
MORE ON ALICE HOFFMAN AND: Television , Hoffman, Alice , CBS Corporation , The Dovekeepers (Book) , de Pablo, Cote (1979- ) , The Dovekeepers (TV Program)
In Alice Hoffman's novel, the mysterious apparition in the Hudson River is really a mermaid from a Coney Island sideshow.
March 2, 2014, Sunday
Alice Hoffman: By the Book
The author of "The Museum of Extraordinary Things" found a copy of "The Catcher in the Rye" on her mother's bookshelf. "I hadn't known that a book could speak so directly to a reader."
February 23, 2014, Sunday
MORE ON ALICE HOFFMAN AND: Hoffman, Alice , Books and Literature , Writing and Writers
The Women of Masada
Alice Hoffman's novel reimagines the first-century siege, through the eyes of women.
October 23, 2011, Sunday
MORE ON ALICE HOFFMAN AND: Books and Literature , Hoffman, Alice , Josephus, Flavius , Jews and Judaism
Thinking Cap: From David Foster Wallace to Bret Easton Ellis by Way of Faulkner
Whose opinion are you more likely to trust when choosing a book to read, a professional book reviewer or someone posting on Google +?
September 27, 2011, Tuesday
MORE ON ALICE HOFFMAN AND: Amazon.com Inc , Faulkner, William , Writing and Writers , Ellroy, James , Ellis, Bret Easton , Hoffman, Alice , Amazon.com Inc|AMZN|NASDAQ , News , Jonson, Ben , Stanford Literary Lab , Wallace, David Foster , Google+ , Books and Literature , Computers and the Internet , Google Book Search
Newly Released Books
New novels by Alice Hofmann, Bradford Morrow, Thelma Adams, Howard Gordon, Suzanne Corso and Adam Schwartz.
January 20, 2011, Thursday
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Short Outbursts on Twitter? #Big Problem
The bounds of Twitter etiquette are being tested as complaints are becoming more commonplace.
October 8, 2009, Thursday
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Fairest of Them All
In this novel, three sisters devise an imaginary world with an invented language as a fortress against trauma.
June 7, 2009, Sunday
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Kiev -Global anti-corruption watchdog Transparency International says its working relationship with FIFA has ended because past allegations of wrongdoing in world football won't be investigated.
Sylvia Schenk, sports adviser to Transparency International, says she is "just astonished" that FIFA "neglected our recommendations."
Schenk and bribery expert Mark Pieth have advised FIFA this year since president Sepp Blatter pledged anti-corruption reforms after a series of scandals.
Pieth gave his first news conference Wednesday as the paid chairman of FIFA's so-called "solutions committee" overseeing changes.
Pieth ruled out investigating past scandals, though he acknowledged they should be examined.
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Big month in the world of golf as the FedEx Cup concludes on the PGA Tour, the Race to Dubai gathers steam on the European Tour and the Sunshine Tour offers local golfers the chance to bank some cash. Oh, and not forgetting the USA v Europe Ryder Cup showdown at Hazeltine!
Kevin de Bruyne - money well spent!
Pedro - what a great player!
Memphis - just you wait and see!
Raheem Sterling - he'll prove you wrong!
Petr Cech - watch out for him!
Andre Ayew - he'll show you who's boss!
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Kevin de Bruyne - money well spent!
Pedro - what a great player!
Memphis - just you wait and see!
Raheem Sterling - he'll prove you wrong!
Petr Cech - watch out for him!
Andre Ayew - he'll show you who's boss!
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Two games into his MLS career, Chicago Fire defender Arne Friedrich will see a familiar face when he looks down the pitch at BMO Field on Saturday.
Toronto FC captain Torsten Frings and Friedrich won 161 caps for Germany between them. Now both call the MLS home.
For the 32-year-old Friedrich, his one-year contract with the Fire is a soccer adventure after a distinguished club career spent mostly with Hertha Berlin.
While some imports complain about the travel in MLS, Friedrich says that won't be an issue for him.
"For me, it's fun to explore the country and so I don't care about the flights," he said from Chicago this week.
Friedrich said he and Frings were "good teammates" rather than good friends, since they played on different club sides.
"He's a good guy," Friedrich said of Frings. "He was a very important guy for the German national team. So we had some good times together."
Frings, who limits his discussions with the media, offered his take on Friedrich via email through a Toronto FC representative.
"Arne is a quality defender and he was my teammate on the German national team at the 2006 FIFA World Cup and at EURO 2008," said the 35-year-old Frings.
"He was an important part of our team and I know he will do well for Chicago and in the MLS."
Friedrich also was an integral part of the German team that finished third at the 2010 World Cup in South Africa. He played every game and scored his first goal for the national team in the quarter-final against Argentina.
He also left with good memories of South Africa and its people, calling it "a very impressive country."
While he is still getting his feet wet in MLS, Friedrich — like Frings — appreciates how the North American league is worlds apart from the fishbowl that is German soccer.
"It's perfect," he said.
He is rarely recognized in the U.S. other than when he runs into Germans.
"The rest, they don't care about me and this is very nice."
Saturday's game will be the first for Frings since he strained his hamstring in the season-opening loss to Seattle.
Friedrich's first MLS game last Sunday proved to be a wild one in a weather-interrupted 1-1 tie with the visiting Houston Dynamo. The match was delayed for 70 minutes in the 13th minute, only to resume and then be called after 66 minutes.
But already he is impressed with his fellow players in the league.
"The players are very fit, they physically strong and can run for 90 minutes. The level is not that bad, as most people in Germany think," Friedrich said. "I guess I can help the team when I get totally fit and I'm working on this every day. But the league is definitely interesting"
He was a late arrival this season, joining the Fire a month ago following their season opener in Montreal after contract negotiations were completed.
His arrival is good news for Chicago, which has lost veteran defender Cory Gibbs for an estimated four-to-six months after surgery to repair his right meniscus.
Friedrich paired with second-year defender Jalil Anibaba in the back against Houston.
He wears No. 23, a number that has plenty of significance in Chicago.
Friedrich explains the choice by saying he wore No. 2 when he started with the German national team before getting No. 3.
"And as well I like the performances of Michael Jordan," he added.
Friedrich played for Hertha from 2002 to 2010, captaining the side and making 231 appearances. He moved to VFL Wolfsburg after Hertha was relegated, playing in 15 games in 2010-11.
His contract was cancelled by mutual consent — "Why is not important," says Friedrich when asked about it.
He took the next six months off from the game.
"It was my decision," he said of the break. "Then I thought about my future. I decided to play one more year, in Chicago because I liked the country."
Friedrich, Frings and New England's Florian Lechner make up the three-man German contingent in MLS.
Toronto FC striker Danny Koevermans knows all about Friedrich.
"Good player," said the big Dutchman.
Friedrich did not talk to Frings ahead of his move to Chicago, although he did consult former Red Bulls goalie Frank Rost about MLS. Still Toronto FC manager Aron Winter believes Frings' decision to come to MLS midway through last season has made MLS more attractive to other international players.
"I think the moment when we brought Torsten in, the eyes were opened for other players in Europe or overseas that 'OK, this league that we might have understimated is a good league.'
"And that's why they want to come here. It's a very good league."
Winter also believes that Chicago coach Frank Klopas looked to Europe and Friedrich "for some players he couldn't find in this league."
While Winter also rates Friedrich as a good player, he like what he sees in Toronto's uniform.
"I'm very happy with Torsten," Winter said with a smile.
Friedrich too is happy with his decision.
"Everything here in Chicago is fine. I like the city, I like the club. The teammates are wonderful and kind. I've had a good start."
Friedrich's girlfriend visited him recently but is back in Berlin now. His parents also came over to see him. He uses the phone and Skype to stay in touch.
He does not rule out a longer stay but says he will let the future take care of itself.Report Typo/Error
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Big, But Weak, Bertha Heads For Shore
Vacationers streamed hundreds of miles inland for a place to spend the night Thursday as a weakened Hurricane Bertha staggered toward the Carolina shores during the height of the summer season.
"We don't want to take a chance," Mary Ann Stibbe of Sylvania, Ohio, said before heading away from Sunset Beach, N.C., where she was vacationing. "There are certain gambles you don't take in your life, and this is one of them."
The center of the hurricane will most likely hit Myrtle Beach around noon today with 80 mph winds, but hurricane-force winds will be felt hours earlier along the Carolina coasts, Hurricane Center Deputy Director Jerry Jarrell said.
And although top winds dropped to 80 mph from 105 mph Thursday afternoon, Bertha is so big - more than 400 miles wide - that tropical storm-force winds of more than 39 mph were already menacing the coasts Thursday night.
Bertha's eye shifted slightly west, but Jarrell said people in North Carolina should remain wary.
"I don't think there's any reason at all that they should relax because they're on the bad side of it," he said.
Jarrell also predicted that Bertha would linger over land, losing strength and focus after hitting the coast.
"Once it gets over land, it'll probably just become a nor'easter," he said, adding that Bertha will dwindle to a rainstorm by the time it reaches cities in the Northeast.
Coastal communities ordered another round of evacuations, sending a two-day total of more than 100,000 North Carolina residents and vacationers to higher ground.


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Property Location With a stay at Loews Santa Monica Beach Hotel in Santa Monica (Beach Cities), you'll be minutes from Original Muscle Beach and Santa Monica Pier. This 4-star hotel is within close proximity of International Chess Park and Santa Monica Place.
Rooms Make yourself at home in one of the 347 air-conditioned rooms featuring MP3 docking stations and minibars. 42-inch flat-screen televisions with cable programming provide entertainment, while complimentary wireless Internet access keeps you connected. Bathrooms have designer toiletries and hair dryers. Conveniences include phones, as well as laptop-compatible safes and desks.
Rec, Spa, Premium Amenities Pamper yourself with a visit to the spa, which offers massages, body treatments, and facials. You're sure to appreciate the recreational amenities, including a 24-hour health club, an outdoor pool, and a spa tub. Additional amenities include complimentary wireless Internet access, concierge services, and babysitting/childcare (surcharge).
Dining Grab a bite to eat at the hotel's beachfront restaurant, where you can dine alfresco (weather permitting). Or stay in and take advantage of 24-hour room service. Quench your thirst with your favorite drink at a bar/lounge. Full breakfasts are available daily for a fee.
Business, Other Amenities Featured amenities include a business center, a computer station, and express check-out. Planning an event in Santa Monica? This hotel has 17000 square feet (1579 square meters) of space consisting of conference space and meeting rooms.


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Becoming a ROADS teacher is a life-changing experience. Join our team and feel what it's like to be the change.>
Eligible students can apply today. We hope it is the first step on your ROAD to success.>
Find out how you can help ROADS to reach even more students who deserve a second chance.>
As the first semester drew to a chilly end, ROADS Bronx played host to a rejuvenating three-day workshop facilitated by Naptural Princess and attended by many of our female students.
Reinventing Options for Adolescents Deserving Success' (ROADS) mission is to ensure that over-age, under-credited students graduate from high school thoroughly prepared to excel academically, professionally, and personally. To achieve our mission, we create transformative high schools characterized by customized and rigorous curricula, socio-emotional support, and work-based experiences that foster student engagement and accelerate student progress.


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$8.99Special edition includes the third and fourth books in this captivating series Holly Cathers is not the same person she was almost a year and a half ago. After discovering her connection to an ancient legacy of witches, Holly has accepted her destiny as a descendant of the House of Cahors. She is determined to end an intergenerational feud that has plagued her family for centuries. Holly
$9.99Who is Alex Carruthers? That is the question Wicked fans have been asking for nearly six years. Spellbound, the fourth and seemingly final book in the Wicked series, originally published in 2003, left readers on the edge of their seats with a classic cliffhanger ending. But now, as new fans of the bind-up editions of the series begin to ask the same question, the true and final conclusion to the
$9.99Holly Cathers and her twin cousins have just graduated from high school, and they're moving on toward their first semester of college. But no matter where they go, they will never be entirely free of their past. The three are descendants of a powerful coven of witches -- in constant danger from a rival clan.Holly learns from a vision that Jer is still alive. As leader of the coven, she resolves to
$9.99Nancy Holder and Debbie Viguie, the New York Times bestselling authors of the Wicked series, have created an entirely new trilogy with the passion of Twilight and the grandeur of Fallen. The Wolf Springs Chronicles introduces readers to a town of secrets and the new girl who's about to start believing in werewolves.From the Hardcover edition.
$6.99Once upon a time in the Kingdom of Aster a strange thing happened.They say the prince married a girl who was not what she appeared and that another girl who saved the kingdom vanished without a trace. Some said it was witchcraft. Some said it was only a legend. For those who knew the truth, it was magic....Rescued from the sea at an early age, Pearl grew up within sight of the water...and the
$9.99Vampires—the Cursed Ones—have declared war on humanity. Most people are too afraid or unwilling to take a stand, but eighteen-year-old Jenn Leitner trains to become a vampire hunter, risking everything in the process. When Jenn falls for Antonio, a vampire fighting on the side of humanity, she discovers a love that transcends attraction and physical consummation. But the closer Jenn and Antonio
$9.99There is a fine line between love and sacrifice…. Antonio would do anything for his beloved fighting partner Jenn. He protects her, even suppresses his vampire cravings to be with her. Together, they defend humanity against the Cursed Ones. But tensions threaten to fracture their hunting team and his loyalty—his love—is called into question. Jenn, the newly appointed Hunter, aches for revenge
$7.99Seventeen-year-old Violet is amazed when a storm brings the dashing Prince Richard to her impoverished family's farm. The two fall in love at first sight, but although Richard has given his heart to Violet, his parents will only let him marry a princess of their choosing, a lady of the highest nobility and sensitivity. Now on a quest to be reunited with her true love, Violet must rely on her wits
$9.99Following the "globetrotting supernatural adventure" (Publishers Weekly) of Damned, the riveting conclusion to the Crusade trilogy pushes the power of love to its limits.Hope is in short supply, but courage runs deep as the Salamancan hunters recover from a devastating loss. Jenn knows she must rally her team against the Cursed Ones, but her focus is shattered. She's torn between passion for
$6.99The True Face of Love Ruth's grandmother lives in the forest, banished there for the "evil" that the townsfolk believed she practiced. But if studying the stars, learning about nature, and dreaming of flying is evil, then Ruth is guilty of it too. Whenever Ruth took food and supplies to her grandmother, she would sit with the old woman for hours, listening and learning. When she wasn't in the
Wolf Springs Chronicles (Book 3)Who do you run to? Out in the forest, tensions are blazing like forest fire. The ancient rivalry between the Fenner and Gaudin packs has reached fever pitch, and only a battle will quell the blood lust. Katelyn is caught in the middle, her pack loyalties tested like never before. The person she needs the most – strong, sexy, loyal Trick – has no idea about her dark secrets. And while werewolf wars
$9.99What do you run from? Katelyn had only been in Wolf Springs a short time before she was bitten by a werewolf. And now she carries that creature's curse in her veins. But she's not alone. Wolf Springs is home to a hidden family of werewolves, the Fenners - who swear none of them bit her. Apparently there's a monster on the loose - something wild and uncontrollable. And to make matters worse,


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I've been 'away' from this blog for a while. It's been a very interesting year for me but I've been neglecting this blog for too long.
If you've read the previous posts, you can see I'm not a big fan of the Asp.Net postbacks and update panels. Too much information is sent back and forth for small actions that can be easily done in javascript.
As I've shown before, there are hugh performance benefits to using client side rendering in a web app. Instead of sending the entire HTML for every request, we load javascript code for creating that HTML once and after that we just send the data for subsequent requests.
One of the side effects of moving from server side rendering is that you start getting more and more javascript files. I've been using JQuery for a while, there are a lot of great plugins for JQuery, but loading all of those include files introduces some problems:
Using a Script Combiner to reduce the number of requests
Ideally you want to have only one js file and one css file, but you don't want to have your files merged while you're developing, a hugh file will be a pain to work with. The solution is to merge all the scripts into one big file later, either in the build process or at run time.
if you use the same scripts for all pages in your app (or if you have a one page app), merging during the build process is a good solution but I needed different files for different pages.
Asp.Net AJAX 3.5
If you're using Asp.Net AJAX 3.5, achieving this is very simple. The scripts from Microsoft will already be combined by default and to add your own scripts all you need to do is include your scripts using the ScriptManager.
<asp:ScriptManager runat="server" ID="ScriptManager1" >
<asp:ScriptReference Path="~/JScript1.js" />
<asp:ScriptReference Path="~/JScript2.js" />
Script Combiner - The Other Solution
If you don't use Asp.Net AJAX and don't want those scripts loaded (or you're still using 2.0) you can create your own handler to combine scripts.
Here's a project I foundby Omar Al Zabir (Who wrote the excellent book Building a Web 2.0 Portal with ASP.NET 3.5 and co-founded PageFlakes)
You might want to change the way you decide which scripts to load, I use an xml configuration file to specify the location of each script file and which js files should be loaded based on the page name that's passed to the handler. (I use the page name as the key for now). I also have a separate path for the minified version and the debug version, and based on a config I use the right one
<Script name="jquery" minPath="Scripts/JQuery/jquery.1.2.6.min.js" debugPath="Scripts/JQuery/jquery.1.2.6.js"/>
<Script name="jqvalidation" minPath="Scripts/JQuery/plugins/jquery.validate.min.js" debugPath="Scripts/JQuery/plugins/jquery.validate.js"/>
<Page name="home" Scripts="jquery,jqvalidation" />
There are several benefits when using this custom handler
Tags: javascript, performance
AJAX | Asp.Net | Javascript
There is a lot of information on the web on using WCF for JSON, but I figured I'll writing something short on the way I use it. When I decided to try WCF, the first thing I noticed was how simple it was to upgrade. All you need to do is add a new WCF Service to the web project, copy the code from the ASMX service, change the [ScriptService] to [ServiceCntract] and the [WebMethod] tags to [OperationContract] and add some definitions in the web.config file. You're supposed to use a separate Interface to define the service contract, but it's not a must and you can add the tags to the actual class with the implementation. The second thing I noticed is that I can get JSON by changing some configuration settings. When I was working on the AJAX search page, WCF was not around (it was by the time I posted the series on it here). I used XSLT to transform data to JSON and arrays. It was another step I had to do on the server side but it's worth it, JSON is smaller than XML and very easy to work with in JavaScript. With WCF I just change a small definition and I get the results in JSON, no need for the XSLT transformation. Another thing we get with WCF is Data Contracts. The way I'm using it in this sample, it's pretty much the same as using the .Net AJAX GenerateScriptType. All I had to do is add a [DataContract] tag to the class and [DataMember] tags to each property. I think it's better to define this on the exposed class itself instead of adding some register definition in a web service. The attached project is the same search page sample with the WCF service. The changes to look for are:
WcfAjaxSearchSample.rar (883.99 kb)
Tags: wcf, ajax, rapidbackoffice
AJAX | Asp.Net | WCF
This week I got certified, I guess. I took two tests, each one took 30 minutes or so, and got an MCTS Web Dev certification. Because it was so easy (and cheap, test prices are 125$ but with discounts you can take a test for 85$) it makes me feel like this certificate doesn't mean much to those who know what it is.
.Net and Visual Studio can make it to easy to just drag and drop to create an application. Microsoft also has a lot of built in tools to make life simpler. Mastering these tools and drag and dropping seemed to be the focus of these tests. Sure, there were some questions about serialization, but after working with .Net ever since the first release (was it a preview or a beta? too long ago to remember) I found that most of the questions were about things I've never had to do.
Even without having experience with some (or most) of what Microsoft decided a .Net web developer should know, it was very easy to pass these tests, I guess after such a long time working with the .Net framework you understand the philosophy behind it and can guess how the folks at MS would've called a method, even f you never heard of it before.
There is a whole business built around certifications, Microsoft offers online courses and books and there are plenty of other companies in the game as well, so maybe it's all about the money, or maybe it's more important for IT certifications (system and network administrators should probably know what their doing, if you let them near the most important servers in your company).
So now I have my MCTS Web Developer certification, my guess is it won't hurt but I'm not sure how much it will help. I was planning on doing a third test to get the MCPD, but the only reason to do it now is to check if that test is any harder.
(btw, according to the Microsoft Learning web site, there are just over 20,000 MCTS Web Dev 'achievers', and 4,500 MCPD Web Dev while the number for certified windows 2003 sys admins is 186,000. This numbers are updated for April 2008, seems like not too many people felt the MCPD is worth it...)
Tags: ms certification, mcts, mcpd
MS Certification
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Army recruiter: Tougher tattoo rules bring fewer, but better, recruits
CHICAGO -- Uncle Sam still wants you -- just not as heavily inked.
More than three months after the Army implemented a more stringent tattoo policy, recruiters say they are feeling the pinch.
"It certainly makes our job a little more challenging," said Staff Sgt. Carrington Oliver, of the South Holland recruiting station.
The new regulations, which went into effect around April 1, mean turning away about 10 to 12 potential recruits at his office each month, Oliver said.
Still, he endorsed the changes. "It's all about projecting a more professional image," he said.
The tighter rules ban body art on the head, face, neck, wrists, hands and fingers. Soldiers are allowed a maximum of four visible tattoos below the elbow or knee, but they must be smaller than the wearer's hand. (Extremist, sexist and racist tattoos have always been taboo.)
The Army has the toughest tattoo policy of all the branches of service. It's not the first time the top brass has banned being overly tatted up, said Wayne Hall, an Army spokesman at the Pentagon.
However, after the 9/11 attacks, when more recruits were needed in Iraq and Afghanistan, the Army took a more lenient stance -- and the inkwell flowed with abandon.
But the Army decided to reassess. Existing soldiers who are noncompliant with the new policy are grandfathered in.
"Any time you make something tougher, you're going to see a reaction. But, ultimately, it's more rewarding because we're bringing on board the highest quality soldiers possible," Hall said.


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Sacramento, CAUSA
May 10, 2011
No introduction yet
Help support your Meetup
We are a fun and friendly group of poker players. The event host will select what type of poker (limit-no limit- tournament etc.) we will be playing that night. Each event will give the details of that particular event and what type of poker to expect. Bring your own bev and snack; if you'd like to, bring a snack to share. Besides poker, focus is on fun and meeting new people. We welcome beginners too!
Our monthly meetup fees are provided by www.roseville-counselor.com
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Screening tests for Colorectal Cancer
Q: I am worried about bowell cvancer.I have had loose motions for several months and am woried that this may be a symptom. I have previously had a rectal examination and more recently a FBC which came back OK. My doctor thinksit may be IBS but I am not convinced-just worried.
A: Colorectal cancer is a common cancer in men, secondly only to lung cancer. If, however, the cancer is detected early through screening, it may be highly treatable and need not be deadly. Depending on your symptoms your doctor may advise one or more colorectal cancer screening tests. Usually the first screening test done by a doctor is a guaiac fecal occult blood test or a fecal immunochemical test. Studies have shown that fecal occult blood test, when performed every 1 to 2 years in people ages 50 to 80, can help reduce the number of deaths due to colorectal cancer by 15 to 33 percent. If however you are still not convinced, you can ask your doctor for a sigmoidoscopy or preferably a colonoscopy to rule out any colorectal cancer.
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Working in IT at times is a daunting task so when an application comes along, that promises to help make things easier -- a lot of folks are willing to go ahead and give it a shot. Such is the case with Spiceworks and now -- they've gone mobile and in doing so have brought a lot of their core features to their mobile application:
- Help Desk – allows IT pros to open, access, edit and manage Spiceworks help desk tickets from their Android mobile device or iPhone.
- Inventory & Monitoring – enables users to view the status of their servers, software applications and cloud services. As a result, IT professionals on the go can stay informed about the health of important network services and devices.
- People View – allows IT pros to access employee contact information from Spiceworks. In addition, they can easily upload employee photos taken with their Android mobile device or iPhone to their Spiceworks user profiles.
- Community of IT Pros – gives users a way to view posts, answer questions, ask for help, and comment on topics that spark their interests from the Spiceworks community of IT pros – all from their Android mobile device or iPhone.
- Low Bandwidth Requirements – because this is a native application, the amount of data sent between the mobile app and Spiceworks is very lean, which means it performs well over a VPN or 3G mobile network.
If you're an IT Pro in need of better mobile management tools you can jump on past the back for more information regarding Spiceworks. It could be just the mobile application you need to regain some sanity in the workplace.
Source: BusinessWire


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It's draft day! The much anticipated event is finally upon us. Franchises are made and broken during these three days of excruciating drama and unpredictability. Fans cheer, boo and are often confused. Judging the results of the draft takes years. Certain players are rising dramatically on many teams' big boards.
Continue on to find out which players' stocks are on the rise.


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Back to game info
Doom 3 BFG Edition Screenshots for PCOn: PC, Xbox 360, PS3
DOOM 3 BFG Edition is the ultimate collection of groundbreaking games that defined the first person shooter. It includes DOOM, DOOM 2, DOOM 3, and DOOM 3: Resurrection of Evil, as well as the 'Lost Mission.'
Latest Articles for Doom 3 BFG Edition
The best and worst Doom box art of all time
A very scientific look at the best and worst Doom box art ever created.
Doom 4 info still off limits, says Carmack
Was told prior to QuakeCon that he couldn't speak about the game's development.
Doom 3 BFG Edition won't ship with Oculus Rift headsets
Kickstarter backers offered an alternative reward.


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Steve Kelman notes that federal agencies have developed a range of valuable techniques for avoiding groupthink.
Read More
Steve Kelman reports on innovations at DHS that could help analysts across government.
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Steve Kelman found himself in London after the big vote, and offers a first-hand report.
Read More
Steve Kelman argues that government needs more leaders with experience in both areas.
Read More
Steve Kelman gets back to his roots, and considers the Big Apple's overtones in this year's elections.
Read More
Steve Kelman argues that cross-agency coordination is not quite as quixotic as he once believed.
Read More
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