text:
Read an Excerpt
"Dude, I can't believe your luck with women."
"That's not luck, my friend. That's an abundance of charm," Detective Diego Sandoval offered with a wicked grin. "And the simple fact that I love women."
And with a few painful exceptions, women loved him right back.
Something that came in handy when he was charming information, and a cast-iron frying pan, out of a three-hundred-pound mass of quivering fury.
"I've never seen anyone so pissed, though. When you arrested her old man, I thought she was gonna knock you on your butt. By the time you left, you had her ready to testify against the dirtbag, handing over evidence and offering to make you a bologna sandwich."
Diego shrugged. He was a cop. That was his job, his focus, his entire life. He did whatever it took to break a case. "Try chilling a woman down while she's aiming a sawed-off shotgun at your goods."
Following Diego up the steps of the large brick building that housed the Central California Sheriff's Field Operations Bureau, Chris Carson shook his head. In admiration or in disdain, it didn't matter to Diego. He was all about the job and he devoted 100 percent to it. He didn't have time to worry about other people's opinions or doing the buddy thing. That's what made him one of the best.
"Someday, Sandoval, you're gonna meet a challenge you can't charm your way through," Chris said as they strode down the hall toward the patrol and investigation offices.
Diego's grin slipped a notch.
"Someday" had happened at birth. Diego had heard tell over the years about such a thing as motherly love, but he'd never experienced it himself. Hell, his mother had barely tolerated him. His learning to talk had been her breaking point. At three, he'd begun the loser shuffle between the rigid disapproval of his uncle Leon's house and the dismissive foster home's revolving door. Every couple of years, his mom would feel the guilt and haul him back. But those dance breaks never lasted.
No matter. That was then. Diego only cared about now.
"Most women don't need weapons," he told the younger man, leading the way through the bullpen. "Mother Nature made sure they were born armed and dangerous."
Before they reached Diego's desk, one of the other cops shouted his name.
"Captain called down a half hour ago, Sandoval. He wants to see you."
"Yeah?" Diego tossed his leather jacket over the back of his chair, then lifted the stack of file folders off the corner of his desk to find one that Chris had been looking for before they left earlier.
The room chilled. Chris grimaced, glancing around for an escape route.
Diego flipped through folders anyway. He wasn't oblivious to the potential drama. He just didn't give a damn. The case was what mattered and he was sure he had one that tied in with the bust they'd just made. If Chris moved on it, they could nail this drug dealer for twice as long.
"I can get the file later," Chris muttered. "Kinnison hates waiting."
"He's waited a half hour. Two more minutes isn't going to matter."
The chill in the room turned antsy, nervous.
Diego kept right on flipping files. For a bunch of seasoned cops, these guys were way too intimidated by the new brass. Captain Kinnison had been on the job for three months, but it'd taken him only two weeks to institute a new order in the station house. An order heavy on rules, regulations and protocol. And politics. All things Diego didn't give a rat's ass about.
Something that hadn't earned him any points with his new boss. Despite that, though, word had come down two days before that he was up for a coveted transfer to the San Francisco Sheriff Department, complete with a promotion to Homicide.
For the most part, Diego was the cocky, lone wolf his uncle claimed him to be. One who didn't look for back pats, didn't see the promotion as a big deal. But a little, rarely acknowledged part of him was like a kid on Christmas who'd just found his secretly dreamed-of present under the treeproof that while he might not be the favorite, Santa still thought he was on the right list.
The move to San Francisco was ideal. Fresno was getting claustrophobic, like the small towns Diego had hated when he was growing up. The promotion to Homicide validated everything he'd done, everything he was. And he was up for it because he was a damn good detective with the highest close rate in Fresno County. Not because of ass kissing and cronyism. Ironic that by insisting on doing things his way, he'd garnered a file full of commendations and a fast-track to big-deal promotion. He'd finally done something that disproved his uncle's and uptight cousins' assertion that he'd never amount to jack.
"Sandoval, in my office. Now."
The command was quiet. Intense. And seriously pissed.
"Good luck," Chris muttered, knocking a chair into Diego's desk in his rush to get away.
"Hey," Diego called before he could get too far. The deputy grimaced, shooting a quick glance over Diego's shoulder before taking the file folder he held out.
Diego tossed the rest of the stack on his desk, ignoring its precarious slide toward the edge. Then he turned to face the captain's stony stare.
"On my way, sir."
Diego had a brief vision of walking the plank toward a very large, very hungry shark. Then he shrugged it off. What was the worst the guy could do? Take a bite out of his ass? Diego stepped into the office. The captain, already seated behind his large desk, inclined his head toward the door. Shutting it behind him, Diego took a seat. Good. Ass bitings were always better done in private.
His face as hard as the oak of his desk, Kinnison didn't waste time with games.
"The D.A. has some issues with yet another of your cases, Detective Sandoval. Since we've had similar chats so often over the past few months, I'm sure you're aware of how much I dislike hearing that you didn't follow procedure. Again. By not playing by the rules, you've compromised the prosecutor's chances of getting a conviction. Again."
A dozen arguments ran through Diego's mind, but he clenched his jaw shut and waited.
"You threatened Geoffrey Leeds with" the captain made a show of looking at the paper in front of him, even though they both knew he didn't need to "an offer to wrap his large intestine around his throat and choke him with it."
"Offer being the operative word, sir," Diego pointed out.
"I didn't threaten. I offered."
"And the difference is?"
"He could have said no. He didn't have to tell me the details of the porn ring he and his buddies were running in the high school gymnasium."
Captain Kinnison's stare could have made a polar bear shiver. Before the older man hauled out his lecture on semanticsagainDiego inclined his head toward the file.
"Didn't the D.A. read the letter Leeds signed, stating that he was volunteering the information of his own free will?"
"He read it. But he feels, as do I, that the defendant might have signed under duress," Kinnison said, a small, tight smile puckering his thin lips. "Which puts yet another open-and-shut case in question, thanks to your methods, Detective."
Kinnison had no interest in hearing a defense, so Diego kept his mouth closed and waited.
The captain didn't make him wait long. He set the file down, then held up a letter. With the morning sun shining through the window behind Kinnison, the logo of the San Francisco Sheriff's Department was visible through the thin paper.
Diego tensed.
He'd seen enough of them to recognize a job assessment form.
"Detective Sandoval, you're up for a promotion and transfer."
Damn. Diego tried to tell himself that not getting the promotion wasn't a big deal. He wasn't looking for a ladder to climb. His ego didn't ride on outside kudos.
But, he acknowledged with an inner grimace, he wanted that job. Wanted the challenge of working Homicide. Wanted, intensely, to get the hell out from under Kinni-son's watch. Wanted it all so bad he could taste the bitter disappointment as he watched it slide out of his grasp.
"You have a strong record with the department," Kinnison mused, running the letter through his manicured fingers in contemplation. "Your peers respect you. The commissioner feels that your close rate is high enough to offset the cases lost by your roughshod style and disregard for regulations. Captain Ferris in SF Homicide is willing to consider your promotion based on my recommendation."
"But?" There was always a but.
"But there are some issues. The first being that you're not a team player. Add to that your lack of respect for protocol, your inability to follow orders and the way you blithely dance all over procedure. I can't, in good conscience, give you a positive evaluation."
Fury and frustration churned in Diego's gut. It was one thing to lose a promotion because he wasn't good enough, wasn't smart enough or just didn't have what it took. But to lose out because he didn't dot his freaking i's and put tidy crosses on his t's? Screw that.
"So you're going to, what? Withhold recommendation?" The mental image of Diego's uncle, wearing the same smug, arrogant expression as the captain, flashed through his head. The old man had always said that Diego's rebellious attitude would be his downfall. Maybe he should drop him a note, let him know he was still right.
"No. Denying you recommendation might be appropriate in this situation, but it wouldn't serve me in the long term."
In other words, while Kinnison would love to screw him out of the promotion as a punishment, he'd given up on making Diego toe the line. So he'd rather get him out from under his command. He just wanted to mess with him before he did.
"Then what's the deal?" Diego asked, wondering how the guy was going to reconcile the two.
"You're going on special assignment."
And there it was. His punishment. And his last chance. That promotion was close enough to taste. And it tasted mighty sweet. But even more appealing was the chance to work under a different captain.
"What assignment, sir?"
"You'll be reporting to the mayor of Diablo Glen in the morning to investigate their little crime wave."
Diablo Glen. Tiny town, nestled in the foothills of Sequoia National Park. Too small to have its own police force, towns like that usually rented out a deputy now and then or had a low enough crime rate that they could rely on the occasional sheriff patrol.
"I don't do small towns," Diego stated, his throat tight. The truth was, he hated small towns. Close-knit, judgmental and unyielding. "My skills are better suited to cities. There isn't a whole lot of vice in the boonies."
"Oh, you'd be surprised." His smile about as friendly as a shark's, the Captain leaned forward to hand a file across the desk. Smelling a trap, Diego hesitated for a second before taking it.
"Diablo Glen has need of your services, Detective. This crime is right up your alley. It seems they have a series of rather odd burglaries."
"My specialty is vice, not burglary."
"The line is blurry in this case." The captain inclined his head again, this time toward the file.
Trapped, Diego opened it. Thirty seconds later, he shook his head. "No way. Absolutely not."
"You're refusing a direct order from a commanding officer, Detective?"
The older man didn't have to voice the threat. It hung there over their heads like a swinging blade, glinting right over Diego's neck. As much as he wanted Diego out from under his command, the guy would veto the promotion if he didn't get his way. Fury and frustration battled for supremacy in Diego's belly as he glared.
"I have no choice at all?"
"None," the captain verified with a smile as wide and satisfied as a cat in a fully stocked mouse house. "You are now assigned to the tiny little town of Diablo Glen until their mayor is satisfied that you've solved this case. And you will solve it by the book. No hotdogging, no skirting the system. To do so, you'll have to play nice with the locals. And you'll have to show the utmost respect for the department's rules and procedure."
Diego's jaw ached from the effort to hold back the furious rant. Finally, when he was sure he wouldn't spew swearwords and abuse, he inclined his head. "I'm going out on a limb here and guessing that my closing this case, your way, is mandatory if you're going to sign off on my promotion."
"Exactly, Detective. You want your promotion, you need to catch a panty thief."


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Glamour Dog Sketch IV, Silver
Item#: 073738D
Dimensions: 22.5"w x 26.5"h
Item#: 073738D
In stock, ships UPS. Expect delivery within 10 days.
Classic design.
Mickey perspective.
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Item#: 073738D
In stock, ships UPS. Expect delivery within 10 days.
Pint-sized in real life, the pooches in our six-part Glamour Dog series fill their transitional silver frames with attitude. Artist April Lake captures their incomparable cuteness perfectly in these embellished giclées on paper, framed by hand in our own U.S. workshops.
Includes innovative system for easy, secure no-wire hanging:
Artist Biography
Growing up surrounded by farms, animals and the desert, April Lake formed a strong connection with nature and the cycle of life. She graduated cum laude with a BFA from Arizona State University in 2005. During her studies, she concentrated on painting and was deeply inspired by the works of Cézanne, Bacon, de Kooning, and Calder. Nowadays, she finds inspiration in gardening and her annual trips to the beaches of Mexico. She shares her home in Tempe, Arizona, with her husband, two dogs and two cats.
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This item has been added to "my projects"

subset: commoncrawl


text:
Threat Description
not-virus: BadJoke
Files detected as 'not-virus:BadJoke' are nasty jokes. These files are not destructive, however the things they do might be unsuitable for certain computer users.
Automatic action
Once detected, the F-Secure security product will automatically disinfect the suspect file by either deleting it or renaming it.
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A kite that pulls in next to nothingRead More »
Tag Archives: airush
A Ways to Kite
Shifty moves and skate-inspired tricks just south of the borderRead More »
TKB Review: 2015 AIRUSH APEX
This is a skatey, load and pop monster that eats up chop like no otherRead More »
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Freestyle, Freeride, Wave, Race or Foil. What do you ride?Read More »
Red Sea Wind
After two and a half months in Brazil, Airush team rider Marc Toth heads back to one of his favorite riding destinations, Hamata, Egypt where he spends a full month training and tinkering with a new drone. Flats waters and the occassional slider, wind ...Read More »
TKB Review: 2015 AIRUSH VARIAL X
This year's Varial X is a completely new animalRead More »
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Sheet in and go with user friendly boosting powerRead More »
2015 Airush Sector V6
Looking for a exceptional light wind, freeride board? Consider thisRead More »
2015 Airush Slayer V3
The Hatteras boys take the Airush's Slayer V3 for a spinRead More »
Inside Airush: Episode One
From designers to workshop managers to team riders, an inside look at R&DRead More »
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For 2015 Airush focused on improving the construction of its kite line.Read More »
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The Airush wave team head to Maui to collaborate with designers on the 2015 Surf SeriesRead More »
2015 Airush Tour with Alex Pastor
For the first time on US soil, the 2013 World Champ starts his tour in FloridaRead More »
Airush's Oswald Smith in the 2015 Airush Team Series VideoRead More »


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roche holding ag-genusschein
BOARD MEMBERS AFFILIATED WITH A. DeAnne Shirley Julius CBE, Ph.D.(Econ)*
Independent Non-Executive Director, Member of Nominating & Governance Committee and Member of Compensation Committee
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MOST CONNECTED PEOPLE TO A. DeAnne Shirley Julius CBE, Ph.D.(Econ)
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text:
To purchase articles, go to https://shop.heinonline.org/.
Table of Contents
Reports to the Reader
...read more
Vaccines represent one of the greatest achievements of medicine, dramatically reducing the incidence of serious or life-threatening infectious diseases and allowing people to live longer, healthier...read more
The regulation of stem cell-based therapies is challenging in many respects, given their unique safety, efficacy and quality issues. At the same time, public interest in these innovative therapies ...read more
This Article describes and evaluates two elements of the FDA's recent operations implicating information transparency: the Transparency Initiative and a reduction in the agency's FOIA b...read more
The United States Food and Drug Administration (FDA) recently signaled its interest in subjecting clinical investigations that employ high-throughput gene sequencing, also called next-generation se...read more
Synthetic biology (SB) is expected to create tremendous opportunities in a wide range of areas, including in foods, therapeutics, and diagnostics subject to regulatory oversight by the United State...read more
The Food and Drug Administration (FDA) plays a unique role in protecting the public health and minimizing the risk of the distribution of unsafe or ineffective medicines in the United States. Perha...read more
The rapidly evolving realm of modern commerce strains traditional regulatory paradigms. This paper traces the historical evolution of FDA crisis-response regulation and provides examples of ways in...read more
FDA warning letters are considered non-final agency actions and thus are not subject to judicial review under the Administrative Procedure Act (APA). The Supreme Court's analysis in Sackett v...read more
Nanotechnology has emerged as an industry with the potential to change many products regulated by the FDA. While the FDA has been regulating products containing nanoscale materials for several year...read more


text:
Don't Forget Fido
This offer includes:
- Overnight accommodations in a Superior Guest Room
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text:
I really enjoy playing pool. I've been a captain of a pool league team for 14 years and have a pool table in my basement. I am a music fanatic and enjoy going to concerts. I like to film the shows as it is a fun hobby to video trade for different shows; I have over 1,000 videos. During the work week I like to relax at home, cook a good meal, and watch a movie. I also have a night out during the week where I go out to play league pool. On the weekends I like to go out to eat, go to a bar, go to concerts, bike ride, play frisbee, play tennis, take nature walks, and attend outdoor activities. I have taken up a love for gardening and have an extensive garden and yard of various flora.
I'm fortunate to be able too enjoy the amenities of a family cabin in Minnesota. I go on vacation there each year and like to collect agates, swim, and relax on the beach.
I also like to take trips to California where I still have a large friend base and know my way around.
I am looking for a companion who would share the same interests and I will give my heart to the right person. I put 100% in a relationship; I'm romantic, passionate, kind, and thoughtful.
Food: seafood! steak! Indian Oven! Home cooking! Garden Vegetables! Pancho Villa Mexican Grill!
2. water
3. sun light
4. family
5. friends
6. music


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text:
Jo Bisso – Love Somebody
1. Love Somebody (10:41)
2. Love Somebody Pt. 2 (4:52)
3. Your Love (6:32)
4. Let's Keep It Together (4:37)
5. Thank You Baby (5:03)
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You write and speak English fluently. Before registering for this course, you should take an online self-assessment test which will determine your correct level of English. This will enable you to register for what suits your level best: 'Business English' or 'Practical English' courses.
To have a full and accurate idea of your level, the first class defines this definitely by means of an oral orientation test which may still refer you to another level.
This course improves your language level and teaches you to communicate correctly in a company environment. More specifically, you will learn how to write clear, concise reports.
You will learn how to write concisely, while keeping your message clear and complete. You will learn how to structure texts in order to enhance readability and effectiveness.
Presently there are no special announcements regarding this course.
Please find in the table below the course fee which corresponds to your status.
|Price code
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|50 (3)


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Marc Faber
Aug 10, 2016
Marc Faber sees S&P 500 crashing 50%, Tesla's share value plunging to zero
May 26, 2015
Marc Faber: To achieve meaningful growth, Modi govt must curtail power of bureaucracy
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Why Faber thinks Obama win is a disaster for business
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Sell-off in the US? Get ready for volatility in Indian mkt, says Faber
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Sep 26, 2011
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text:
William B. Travis Middle School students recently delivered barrels, or rather, baskets, of fun to youngsters at Whittier Elementary School.
Members of the Travis Teen Time group put together almost 80 Easter baskets for Whittier pre-kindergartners and their four teachers.
The middle-schoolers delivered the baskets during the week before the Easter holiday.
The service-learning project was one of several being tackled by Teen Time, an after-school program operated on campus by Buckner Children & Family Services.
© 2016. All Rights Reserved. | Contact Us


text:
Many investors own high dividend-yielding stocks not only for the income that they produce but because of the presumed defensive characteristics of these stocks. It is widely believed that a high divided yield essentially "protects" a stock against general market declines.
This has historically been true, for the most part, in terms of relative performance. Indeed, during the recent market decline, although high-dividend yielding stocks have declined in value substantially in absolute terms, they have still outperformed the general market (NYSEARCA:SPY) handily.
However, there is reason to believe that if the current correction turns into a more intense sell-off, that high dividend yielding stocks in such traditionally defensive sectors as MLPs, income trusts and income-oriented closed-end funds could face a devastating collapse. Examples of some vulnerable stocks might be EEP, KMP, PGH, ERF, FOF and ZTR.
There are three reasons for this:
Hedge funds, mutual funds and individuals have been employing leveraged strategies employing normally low-beta high divided paying stocks in order to maximize income.
One popular leveraged strategy is simply to buy dividend-producing stocks on margin. With margin interest rates below 1%, buying high yielding dividend stocks has appeared to be as easy as "printing money." The problem is that if stock prices drop sharply, investors will be forced to liquidate positions, either due to margin calls or due to stop losses.
Another increasingly popular strategy to maximize income has been to sell naked puts and calls with strike prices below and above the current share price. The problem is that such a strategy can prove deadly, producing margin calls and forced liquidation if the price of the stock drops swiftly.
Many traditional fixed income investors have been lured into high dividend yielding stocks simply because the dividend yields offered on stocks in sectors such as MLPs, income trusts and closed-end high-distribution funds are substantially higher than those offered by fixed income securities.
The problem is that most of these former fixed income investors are not used to handling stock market volatility. That is precisely why they were formally invested in fixed income in the first place.
Many of these former fixed-income investors will not handle volatility well and will liquidate positions in a panic if the principle value of their holdings decline below their cost basis.
Never before modern history of the US stock market have dividend producing stocks been so overvalued relative to the market as a whole and growth stocks in particular. Many factors discussed here have been driving this anomaly. This relative overvaluation has reached almost bubble-type proportions.
For example, it is common for stocks in the MLP and income trust sectors to sport PEs in the 20s. By contrast, quality US growth stocks such as AAPL are trading at forward PEs in the low teens and some quality growth stocks like ORCL and SNDK are trading at forward PEs in the single digits.
Given average growth rates of zero and even negative in sectors such as the MLPs, income trusts and high-distribution closed-end funds, such a valuation discrepancy is absurd. While the PEGs of high-growth tech stocks in the US are consistently below 1.0x, the PEGs of high-dividend producing sectors are consistently between four and infinity. There is no question that this enormous anomaly will correct itself in time. And in a bear market, such an anomaly will tend to correct itself through the relatively overvalued stocks collapsing to the downside in absolute terms.
Dividend income investors should beware. In the event of sharp stock market declines, stocks in high-dividend yielding sectors such as MLPs, income trusts and high distribution yield CEFs are vulnerable to a very nasty collapse.
Investors should recall the frightening collapse that occurred in 2008 and 2009 in these traditionally defensive sectors.
While one might ordinarily be inclined to think that such an occurrence could not repeat itself, the fact is that the thirst for yield has increased the risk profile of the asset class both in terms of the types of investors holding these stocks as well as the leveraged strategies being employed by the holders. Furthermore, the level of overvaluation of these sectors relative to the market as a whole, and growth stocks in particular, is much greater today than it was in 2008-2009.
Disclosure: I have no positions in any stocks mentioned, and no plans to initiate any positions within the next 72 hours.


text:
"At a time of rapid globalization and growing instability, global health is emerging as an important concept and has been adopted as a key policy theme by the UK Government.
The APPG on Global Health is connecting parliamentarians with a growing global health community of academics and civil society groups, to inform and improve policy in this vital area"
If you'd like to receive announcements about our events, publications, reviews, or latest news, please email us.
Dan Poulter MP and Lord Nigel Crisp
Chair and Co-Chair of the APPG on Global Health
29th June 2015
The report has been prepared by researchers from the London School of Hygiene &Tropical Medicine and describes the UK's footprint on health globally across the four sectors of academia, government, commerce and not-for-profit activity and shows that the UK plays a leading role in each sector. Its global contribution is second only to the US which it surpasses in some areas.
We have had a series of interesting and very well attended meetings over the last few months including ones on women's health (led by the George Institute from Oxford); polio (led by the Graduate Institute from Geneva); Ageing (led by Kings College); and the new Global Strategy on Human Resources for Health (led by the WHO and UNICEF).
A major focus over recent weeks has been following up the report on the UK's contribution to health globally. This has had very good traction – with the introduction of a number of the ideas into the plans for the Prosperity Fund and excellent meetings with the (former) Ministers in Health and DFID – which were influencing their plans for UK partnerships.
Brexit means that the idea of developing the UK as a global hub or centre for health – just as it is a financial one – has become even more important. We need a vision of an outward looking country, a leading player in health, bio-medical and life sciences, which not only is highly influential – developing global public goods – but also economically successful in one the fastest growing set of industries in the world. We have therefore been seeking opportunities to make this case to the new Government. Any advice or help with this will be greatly welcomed.
The group AGM will be held at 4pm on Tuesday 13th September
Several autumn events around global health competencies, collaborative working between European and African Research and maximising the UK contribution in Sierra Leone, have been agreed and will be announced shortly.
A review group of APPG members has been undertaking a major review of the development of nursing globally over the last few months, holding a number of witness sessions, collecting evidence and debating our findings with the RCN, ICN and others. The report "Triple Impact – how developing nursing will improve health, promote gender equality and support economic growth" sets out a radical agenda and argues that the UK should play a major role in developing nursing globally.


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Expanding Use of NGS Has Largely...
Developers of DTC Genetic Testing Are...
NSCLC is "Major Battlefield" as Merck,...
LC-MS Gains Favor Due To the...
Patients who carry one particular functional polymorphism of an enzyme responsible for clearing dopamine from the prefrontal cortex region of the brain are more likely to respond to placebo therapy than those with a different variant of the enzyme, as long as the placebo is administered in a caring, positive manner, researchers report. The polymorphism generates a less-active version of the enzyme catechol-O-methyltransferase (COMT), which is less efficient than the native enzyme at mopping up dopamine that has been released from nerve synapses.
Dopamine has previously been linked with placebo response in pain, Parkinson's disease, and depression, and the prefrontal cortex—where COMT is crucial for dopamine clearance—is a brain region activated during the placebo response, report the investigators at Beth Israel Deaconess Medical Center. Given that the less-active methionine (val158met, or just "met") polymorphism of COMT has itself been linked with variations in memory function, cognition, confirmational bias, pain processing, and sensitivity, Ted J. Kaptchuk and colleagues revisited their prior clinical study on placebo response in IBS patients to see whether the COMT met polymorphism also impacted on how likely the participants were to have responded to placebo therapy.
This original study had involved three different treatment arms. Participants in one arm were not given any treatment (the "waitlist" group, which acted as a control), those in a second "limited placebo" group were treated using placebo acupuncture in a businesslike, clinical manner (i.e., with little support), while the third cohort of patients was treated using the same placebo acupuncture, but from a warm and supportive healthcare provider who expressed confidence in its effectiveness. This was the "augmented placebo" arm. The trial data showed that the cohort that received the more positively administered placebo treatment were far more likely to respond to therapy in terms of improved IBS symptoms and other measures.
To see whether there may be a genetic component to the likelihood of placebo response the Beth Deaconess have now gone back, genotyped blood samples from the patients involved in the study, and used regression analysis to marry genotype data with the type of treatment received. The results were striking, but only among patients in the augmented placebo arm. In this cohort patients who were homozygous for the met allele (met/met) showed the greatest improvements in their IBS symptoms.
In comparison, patients carrying two copies of the native "val" polymorphism (val/val) showed the least improvements, and those who were heterozygous (val/met), had an intermediate response. There was a direct, and linear relationship between the number of met alleles, and the treatment response. A much smaller met/met-associated effect was observed among patients in the limited placebo treatment cohort, and there was no effect at all in the waitlist control group.
Effectively, the data indicate that the COMT val158met allele could represent a marker for placebo responders in IBS patients at least, the investigators state. And inclusion of the control waitlist patients, who were by far the least likely to "respond" and didn't show any link between response and COMT polymorphism, acted to support the notion that met is a true predictor of the placebo effect, and not just improvements in general.
"To our knowledge, this is the first study to demonstrate genetic modulation of true placebo effects disassociated from changes related to disease natural history and regression to the mean," they write in their published paper in PLoS One. "It is also the first study to demonstrate a relationship between different levels of placebo treatment and COMT genotype."
In fact, they point out, although a number of studies have previously looked at the placebo response, it's the addition of a no-treatment control arm (the waitlist group in this case), and an 'augmented' therapy arm that has provided a clear demonstration that a genetic factor can play a role in whether patients will respond to placebo, albeit with subjective (in the case of IBS), but measurable improvements in symptoms.
"It is unlikely that a single locus like COMT fully accounts for a complex behavioral phenotype like placebo response," the team admits. "However, given that COMT val158met is a functional polymorphism, which results in a three to four-fold reduction in prefrontal dopamine, it has a greater potential to contribute to behavioral variability than other non-functional or noncoding polymorphisms." The team also points out that their findings reinforce how powerful the patient-doctor interaction can be in terms of enhancing healing. And their data indicate that genetics may play a role in whether the patient is refractory to this positive interaction. "Our findings that val/val patients are less influenced by the placebo treatment, regardless of whether it is delivered in an augmented or limited context, potentially shed some light on this clinical challenge."
The implications for drug developers undertaking clinical trials are also evident, Dr. Kaptchuk adds. "Our study is only the first step, and our findings are preliminary, but we hope that as further research unfolds, the implications and expansion of these findings might contribute to improving both clinical care and the efficiency of conducting clinical trials."
Dr. Kaptchuk et al., describe their findings in a paper titled "Catechol-O-Methyltransferase val158met Polymorphism Predicts Placebo Effect in Irritable Bowel Syndrome."
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Analyst: Android, Not iOS, To Dominate Mobile Market By 2017
Android was found on 44 percent of the world's smartphones in 2011 and by 2017 will hold 48 percent of the market, predicts research firm Ovum.
The 50 Fastest-Growing Members Of The Solution Provider 500
Some 59 CRN Solution Provider 500 members appeared on Inc.'s list of the fastest-growing private companies, with many cultivating expertise in security, data analytics or cloud to fuel their growth.
Tech Disrupters: Clearing The Roadblocks To Selling Cloud In The Channel
Executives spoke with CRN about what they're doing to help make it possible for partners to make the cloud transition.
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They could have been my sonsJuly 05,2014Three teenagers kidnapped and murdered by the terrorist organization Hamas deserve our moral, political outrage and response.
Our president and the first lady found the time to express and engage the media when Trayvon Martin was killed. Mr. Obama noted Trayvon could have been his son. Both joined a media campaign for the kidnapped school girls in Africa. Neither put the same effort or focus on these three boys, one a United States citizen. Mr. Leahy, our senator is virtually silent.
The terrorists barbarism is the mother source for the lack of resolution. Our secretary of state, Mr. Kerry, asks for calm in the response to this deplorable crime.
The silence and tepid response of our representatives is shameful. The mournful wails of the families and all those who find the pain and loss of these three children will not go unheard.
They could have been my sons. They could have been yours.
BomoseenMORE IN LettersSo far in the debate over resettling Middle Eastern refugees in Rutland, its been all about... Full StoryRecently, I heard a debate between the two major candidates for Vermont attorney general,... Full StoryLarge mega agricultural operations affect us on so many levels. Full Story
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text: On Wed, 2009-02-04 at 20:38 +0100, Nicholas Allen wrote: > Seeing as the user may pull from this when first trying out Bazaar In fairness, I wouldn't really expect that the first project that someone would checkout with a freshly installed bzr package would be the bzr sources - most people are usually fairly high up the sophistication curve before they need to checkout the sources to their version control tool. But yes, > I think it would be good for Bazaar's image if it used the format that > gave the best performance. Given things like Gentoo ~arch and Ubuntu PPAs, I'm not sure that it would be that unreasonable for the Bazaar hackers to keep their own code in the best format available in the most recent public release [available in such places]. And, it's not like it's hard to build bzr from source. Anyway, their call to ensure people working on some ancient Debian version can checkout the source code to bzr with bzr. They seem to think that's important. To be honest, the real travesty is that things like Ubuntu Intrepid don't have the most recent version of Bazaar in them. Not very supportive of one group of Canonical employees of another group of Canonical employees. AfC Sydney -- Andrew Frederick Cowie Operational Dynamics mobile +61 4 1079 6725 office +1 646 472 5054 -------------- next part -------------- A non-text attachment was scrubbed... Name: not available Type: application/pgp-signature Size: 197 bytes Desc: This is a digitally signed message part Url : https://lists.ubuntu.com/archives/bazaar/attachments/20090205/28cd717f/attachment.pgp


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To the Editor:—
I would like to add some comment to your editorial of Oct 18 (194:231, 1965), "Circadian Rhythms."During the last several years, knowledge of circadian rhythms in animals and in man has been marked by considerable progress which clearly indicates the fundamental importance of these rhythms for medicine and biology.Your editorialist declared that the origin of circadian rhythms can be exogenous in certain cases and endogenous in others. Since the work of Bünning on plant life, and that of Pittendrigh,1 Halberg,2 and Aschoff3 on animals and man, it is no longer possible to regard circadian rhythms, in particular, and biologic rhythms, in general, as having an exclusively exogenous origin, and, more precisely, as being acquired by each individual in each generation.The results of experimental research suggest that:At all levels of organization, rhythmic activity appears as one of the fundamental
At all levels of organization, rhythmic activity appears as one of the fundamental
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Super heroes wave Wisconsin flag on new book cover
The Justice League of America is hailing Wisconsin, and no politics are involved.
This is a shoutout from such super figures as Green Arrow, Katana, Martian Manhunter, Hawkman and Catwoman, who will appear on a DC Comics book waving a Wisconsin state flag high as their banner. »Read Full Article
Madison-formed Garbage to play first Milwaukee show since 2005
Garbage, the Madison-born band behind such '90s alt-rock hits "Push It," "Stupid Girl" and "Only Happy When It Rains," is playing the Rave April 6, its first Milwaukee show since 2005.
Beyonce lives up to hype with fierce Super Bowl halftime set
Has there ever been a 12-minute set as hyped as Beyoncé's Super Bowl halftime show Sunday? The widely publicized press conference, the Destiny's Child reunion rumors, the bold promise of live singing after that lip-synching scandal at Barack Obama's inauguration. Was there any possibility whatsoever it could live up to expectations—especially since the vast majority of Super Bowl halftime shows are bloated, ultimately forgettable diversions?
Danceworks program explores delights of 'Serendipity'
"Serendipity" is high on the list of great words we don't seem to use often enough.
Exploring the word's dictionary definition of "happy accident" or "pleasant surprise" with modern dance, the Danceworks Performance Company and a handful of guest artists built a delightful evening of dance around the word. "Serendipity" opened this weekend in the company's studio theater. »Read Full Article
Next Act's 'Clockmaker' has strong acting, too many gears
We can't turn back the clock. But can we mend what's broken, reconstructing the past's shattered pieces so that we might keep on ticking into the future?
That's the question - or one of them - in Stephen Massicotte's "The Clockmaker," the 100-minute play that Next Act Theatre unveiled over the weekend, under Mary MacDonald Kerr's direction. »Read Full Article


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The NHL Atlantic Division has produced the Eastern Conference champion in three consecutive seasons, and six of the nine seasons over the past decade.
Most of that can be credited to having arguably the best goalie in the history of the game in net: Martin Brodeur led his team to three of the six appearances, and the Pittsburgh Penguins (two) and Philadelphia Flyers (one) got there by building a team that could score against him.
The Atlantic also has recently been the deepest division, with four teams regularly making the playoffs and three division winners since the lockout. These battles during the regular season have them primed for the playoffs, but also make it difficult for them to earn the top seeds.
Without further adieu, the preview of the division commences; check out this link to my regular season predictions to see how each team will be seeded in the East.


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Top Definition
Uplifted Society also known as UPSO is a Toronto based clothing line that represents one with an "Uplifted" mind. It us owned by Kedre and Tyrone. Upliftedsociety.com
Yo, I just copped my UPSO crew neck that says Uplifted Society on the chest from Upliftedsociety.com
simplysymmie가 작성 2014년 02월 23일 (일)
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Revolver Forums
Llama Super Comanche, can it be fixed?One of my family members brought me a Llama Super Comanche .44 magnum with some issues. They bought it at a garage sale hoping I could do something with it. At a minimum, the yoke is warped, and the ejector rod may be having problems as well. They haven't made these since 94, and Numrich doesn't even stock any parts for them. Is there anything that can be done?
Do you have a "Sunday-go-to-meeting gun?"About three weeks ago, as I was getting ready to go to Sunday School and Church, I swapped my old Ruger .44 Special out for this new one:
Detail Stripped & Cleaned up the 66Decided to ckean the 66. I detail inspect all my new acquires to make sure no one has bubba'd up the innards. Other than a lot of crud which cleaned up nicely this model 66 was in great shape. Did forgot to take a final pic of how she looked all cleaned up inside. No rust inside just some dried up crud. All clean and oiled up even smoother than before.


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I went to my first academic conference. I learned some things.
John Warner
Most Recent Articles
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Thoughts on a tricky genre.
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Student-centered learning isn't just a buzzword.
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An experiment in podcasting as academic community building and, believe it or not, trying to have some fun.
August 23, 2015
As I attempt a new experiment in grading, I have to confront my ego.
August 18, 2015
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Two of the most meaningful things in my life are more similar than I ever thought.
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I have very few hopes for the future of higher education, and yet, I don't despair.
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When someone wants you to believe your work is an illusion, you should be worried.


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Top Definition
positive term of address used to connote respect, wisdom and experience in a person, usually male who appears youthful
"What's goin' on old boy?"
od uživatele thickduff 21. prosinec 2004
Trending Now
Can you define these popular missing words?
A pronoun used in place of a male name and usable in the role of both he and him.
Oldboy's gettin rage drunk tonight.
od uživatele Jabroni guy 04. červen 2007
your big wang mate. (in other words: penis)
she whipped out me old boy and gave it a tug
od uživatele MD MACHINE 18. prosinec 2013
A shortened text for "good old boy". Often shortened to "ol boy".
A positive reference to someone as an ok kind of guy.
A positive reference to someone as an ok kind of guy.
That old boy there is a pretty fair hand.
Who is that ol boy standing next to Ralph?
Who is that ol boy standing next to Ralph?
od uživatele ROWLV 23. květen 2016
From the movie "Oldboy" based from the Japanese Manga of the same name. Definition: "To have sex with your daughter, and you don't even know it while cutting your tongue out and getting hypnotized thinking your daughter is your lover."
You sicko! You are an oldboy!
od uživatele L. Sosodef 08. duben 2005


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Fresh Wednesdays, 10 am to 2 pm
Enjoy live entertainment and shop the Farmers' Market. Pick up seasonal Ontario-grown produce, baked treats, meats, cheeses, honey, flowers and more. The market runs from June 4 to October 15, closed June 25. Guided 20 minute tours of the Farmers' Market, including samples, on July 16, 30 and August 13 & 27, 10 & 10:30 am.
Tasty Thursdays, 11 am to 2 pm
Food vendors and trucks from across the city serve up international cuisine including Asian, Indian, Latin America, Cajun, Italian and Greek favorites.
Produced by the City of Toronto. For more information, call 311 or visit toronto.ca


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Off-Campus Dining:
There are a lot of restaurants that deliver.
Off-Campus Dining:
Nothing special but venues exist if you really need something delivered. The restaurants themselves are poor quality and now that I drive and can go further I never stop I. The town nearby.
Off-Campus Dining:
Because you're on post you don't really have food outside of the mess hall unless you pay way too much or wait for delivery. Definitely not the highlight of the school.
Off-Campus Dining:
I've gotten sick more than once.
Off-Campus Dining:
There is really nothing in the town off post, Highland Falls. You have to drive at least 15-20 minutes to get something of diversity and that is healthy.
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Almost none of the cadets are satisfied with the amount of restaurants in Highland Falls. The area is pretty much devoid of fine dining. A lot of times, your options are so limited, you will feel as if you have been to the same place a million times. There are, of course, the staples of any college diet—pizza and Chinese food—and cadets seem to get sick of this food nearly as quickly as they get tired of eating in the mess hall. If you order out, you have three options: You can order from McDonald's, you can order pizza, or you can order Chinese. That's it.
Although the majority of cadets seem to get tired of the mess hall food, they don't feel justified complaining since the mess hall food is free. Food off campus is obviously not free, so the cadets are much more willing to complain. What's there really isn't that bad. There just isn't much of a selection available. For a lot of the cadets, the lack of alternatives has made them more appreciative of a good, home-cooked meal. So it's not all bad news.
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HourlyLess than 30 hrs/week
Intermediate LevelI am looking for a mix of experience and value
We have old plans of two buildings that need to be re-drawn to Autocad.
We also need to combine the two wings of the building to one sheet and it needs to be in scale.
We are looking for an experienced Architect/Draftperson to do this work.
Must be able to start within a week.
We need someone that checks his or her email once per day and can respond to emails within the next day.
When responding to this ad do not start off with "Dear Hiring manager"
Do not send me the canned application email.
Please write a short unique email on why you are qualified and want to do this work.
We also need you to tell us how long each sheet may take in the conversion- We need in 2D scale- walls, windows, doors, room labels, wall dimensions, kitchen cabinets, and bathroom.
We do not need converted- symbols, notes, tables
Activity on this Job
Last Viewed by Client: 3 years ago
Hired: 1
About the Client
United States
Honolulu 12:27 PM
Jobs Posted
64% Hire Rate, 1 Open Job
Over $40,000
Total Spent
41 Hires, 6 Active
Avg Hourly Rate Paid
4,187 Hours


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Steampunk Mock Movie trailer; Fantasy History at it's most exciting!
25 backers pledged $275 to help bring this project to life.
Successfully raised $275 with 25 backers
That would be more exciting if it wasn't mundane things like trash bags, paper plates, plasticware, etc. However those things will be awesome to have when we're there. Thank you... Read more
Project launched


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Names of fallen of 9/11 designed into the stripes of the American flag
THE POST-SIGNAL / Danette Bourque
The Woodmen of the World, Crowley Lodge 6, honored the heroes and victims of September 11, 2001, with a ceremony at their hall recently. This year a new flag was raised, which was made for the 10th anniversary. It has the names of the fallen of 9/11 designed into the stripes of the American flag. Among those present were, first row from left, Lee John and Sheriff Wayne Melancon; second row, Geneva Laurent, Laurna Mills, Charleen Melancon, Ted Seaton (president, Lodge 6), Tracy Young, Thelma Landry, Alberta John and Kitty Seaton; third row, Mayor Greg Jones, Sergeant Wayne Perry, Desi Doise and Chester Guidry (vice president, Lodge 6.)


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Businesses interested in working with us, or already doing so, can now visit our business resources site »
This paper critically examines the FSC and PEFC -- two certification programs at different stages of development.
An evaluation of its ecological, economical and social impact.
A study of the approaches adopted by Forest Stewardship Council® (FSC®)-certified companies to meet Principle 3 of the FSC standard.
How we are conserving natural resources and ensuring sustainable livelihoods while helping businesses thrive.
An evaluation of forest management certification in the tropics.


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In June 2011 the Guardian carried a report on a proposal by Mr Davies. It seems that he could see nothing wrong with a disabled people working for less than the minimum wage. Davies may not have been proposing any sort of complusion but he could see nothing wrong with a disabled person offering to work for a reduced wage. His argument seemed to be that if a disabled and abled bodied person both applied for the same job the able bodied person would obviously be selected. The only leverage he seemed to think was available for the disabled person was to undercut his or her rival. That is to offer to work for less.
There is so much wrong with his idea.. It assumes the disabled person is not worth employing. It promotes jobs going to the lowest paid employee and more. Think about it and it is not easy to see what is wrong with his loony idea. bAt the time he accused those who objected to his view as having "leftwing hysteria"
If you think you have seen Mr Davies in the news elsewhere this week you would be right. A couple of days ago he was blasted as one of four MPS who had accepted Corporate tickets to one of the most over subscribed events in the London 2012 Olympics. He began toady's interview by answering questions on that score. He said he sees nothing wrong with accepting the tickets having been part of the committee overseeing the Olympics. Most people in the UK may disagree.
Today as he argued the case for the restoration of the death penalty in the UK, the MP for Shipley used Florida as an example. There was a film of a visit he made to Florida where he sat in the electric chair, as he pondered the issue.
He appeared to marvel at Florida, its strict laws and unforgiving death penalty. Is he nuts, this blogger thought?
Currently in Florida there is the unresolved case of George Zimmerman killing an unarmed young black man. After shooting Trayvon Martin to death George Zimmerman has yet to stand trial. So much for tough justice in Florida. Florida's stand your ground law almost encourages citizens to defend themselves in a heavy handed manner. If there had not been a public outcry Zimmerman would not even be facing trial.
You have to ask if Florida law is so just and so tough why it has not impacted positively on the number of murders.Dig a little online and you will find plenty of negative issues regarding Florida and its death penalty. Racism and injustice appear to be rife.
So why is Davies extolling its virtues? Another Tory voicing ill thought out opinions, and jumping on bandwagons, it seems.
Tags: Capital punishment in UK, death penalty in UK, Tory MP Philip Davies


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Hi! I'm new here. Just got my self a WII console. I love it!!
You new? See this!
Wii U FAQ
Spoiler Alert!
TNOG.ORG - Games events in Manchester
MikeDBloke - PSN
I was into weird games before people knew what they where
@D_Bloke - My inane prattle
Forum Rules


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Sometimes, for whatever reason, a player just doesn't fit on his team.
He might be overpaid. His skills might be redundant. Maybe a younger player needs more room to develop. Or perhaps, it's just time for a new situation—a better fit.
Almost every team in the NBA has at least one of these misfit toys. Some have an island's worth.
After examining all 30 rosters, I've picked a player from each who isn't necessarily the most likely to be dealt, but the one who should be.
My selections were based on the contract details of the players and the makeup of the remainder of the team on which they currently find themselves.
All stats courtesy of Basketball-Reference unless otherwise noted.


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Portlandia is a Peabody Award-winning satiric sketch comedy television series, set and filmed in (and near) Portland, Oregon; it stars Saturday Night Live cast member Fred Armisen and Carrie Brownstein, lead guitarist/singer for Wild Flag. The show is produced by Andrew Singer and Jonathan Krisel for Broadway Video Television and IFC Original Productions. It debuted on the Independent Film Channel (IFC) on January 21, 2011.
The name Portlandia refers to the sculpture of the same name above the entrance of the Portland Building on Fifth Avenue in downtown Portland, a statue appearing in the show's title sequence.
As of March 2012, 16 episodes of Portlandia have been produced and aired for the show's first two seasons. IFC announced a third season of 12 episodes, with a season premiere in January 2013.
Brownstein and Armisen first met in the early 2000s and began collaborating on a comedy series of sketches for the Internet in 2005, under the name Thunderant. The sketches became...


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Freightliner of St. Cloud Revs the Engine at SCTCC
Posted: 02/15/2013 - 9:57am in News
"Technology is changing rapidly, and we need to keep up." That's the word from Jon Pearson, General Manager, Freightliner of St. Cloud. And, his organization is leading that effort.
In January 2013, Freightliner of St. Cloud announced the donation of a custom-built Detroit DD15 training...(Read full article)
Bone Marrow Donor Registry Drive
Posted: 02/13/2013 - 10:15am in News
Thousands of patients with blood cancers and other life-threatening diseases need a bone marrow transplant. They depend on a perfect match — someone like you. The cure for blood cancer is in the hands of ordinary people making an extraordinary gift.
Joining the Be The Match Registry is...(Read full article)
VEX Robotics Competition Returns to St. Cloud
Posted: 02/13/2013 - 9:55am in News
The VEX Robotics Competition at River's Edge Convention Center on March 2 will be the area's second consecutive world-qualifying event. Over 30 teams from high schools, Boy Scout troops, and 4-H programs from around central Minnesota will compete. The event is cosponsored by the St. Cloud...(Read full article)
SCTCC Gives Kids Something to Smile About
Posted: 06/03/2014 - 3:50pm in News
On Saturday, February 2, 2013, up to 40 local children will see a dentist. For many, it could be the first time.
St. Cloud Technical & Community College is hosting its 8th Annual Give Kids a Smile Day for kids between the ages 3 and 17 who may not have access to dental care. The...(Read full article)
Cyclones baseball starts season ranked 5th nationally
Posted: 07/26/2013 - 10:59am in Athletics
Coming off their first NJCAA College World Series appearance, the St. Cloud Technical & Community College Cyclones baseball team is ranked 5th nationally in the pre-season Collegiate Baseball coaches' poll and the NJCAA poll.
Kevin Kramer is ranked 2nd as stolen base leader.
...(Read full article)
SCTCC alumna makes art history
Posted: 01/03/2013 - 10:56am in Alumni
International silver medalist in surrealism artist Sarah Drake announced today that her artwork was invited to stay on in the permanent collection of the Marina Tsvetaeva Museum and Cultural Center in Moscow, Russia. Sarah Drake is a Central Minnesota artist who is known for her abstract and...(Read full article)
$3,606 Closer to Celebrating More Birthdays!
Posted: 01/09/2013 - 1:57pm in News
Eight SCTCC Student Organizations rallied together November 29, 2012 for the 9th Annual Campus Cancer Walk. Their efforts have added to the 9-year Campus Cancer Walk total of $36,949 collected for the American Cancer Society.
Thank you to the Student Organizations for organizing...(Read full article)
10,000 meals+ packed for kids in need
Posted: 01/09/2013 - 1:56pm in News
On November 20, SCTCC students, faculty and staff rallied to package meals for starving children. More than 10,000 meals were prepared and packaged to be sent to children and their families for the holiday season. Donations were also collected.
The event was organized through Kids Against...(Read full article)
Help the fight against hunger
Posted: 01/09/2013 - 2:01pm in News
Every year, 15 million children die of hunger. You can help change that.
Kids Against Hunger packages highly nutritious, life-saving meals for starving children and malnourished children and their families in developing countries and the United States. SCTCC is hosting a Kids Against...(Read full article)
Ceremony Sounds the Horn for DRIVEN Project Start -- October 8, 2012
Posted: 04/04/2013 - 3:46pm in News
Sound the horns! SCTCC students, faculty, advisory board members, and industry partners joined state legislators to kick off the expansion and renovation of Medium/Heavy Truck and Auto Body programs. The long-anticipated project is funded, in part, through a $4 million capital bonding award and...(Read full article)


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In the first year the following Club Foundations have been invited to be a delivery partner: Bradford Bulls, Castleford Tigers, Huddersfield Giants, Hull FC, Hull Kingston Rovers, Leeds Rhinos, London Broncos, Salford Red Devils, St Helens, Wakefield Trinity Wildcats, Warrington Wolves, Widnes Vikings, Wigan Warriors, Doncaster, Sheffield Eagles, Newcastle Thunder, Whitehaven, Workington Town, London Rugby League, Oxford, University of Gloucestershire All Golds and Coventry Bears.
The Sky Try programme aims to 'make a difference by increasing the amount of viewers, spectators and participants to Rugby League. The RFL view this as a great opportunity to develop and grow the sport by ensuring all projects adopt the following principles:
The Sky Try Programme has four distinct pillars as shown below which have specific targets and outcomes based on the guiding principles.
Sky Try Primary Rugby League: is delivery in a clusters of primary schools selected located around targeted community Clubs targeting 8-9 year olds (Key Stage 2). Each primary school will receive a minimum of 5 weeks consecutive coaching, followed by a recruitment event such as an assembly or participation festival. All Primary teachers in the Sky Try project will be offered CPD. Community Clubs will be selected to work as targeted partners for participation by the Sky Try deliverer. The Sky Try deliverers will work with these Clubs to help upskill coaches at Primary Rugby League age groups through running coach development CPD, and actively recruit participants who have received delivery in the primary school.
Sky Try Local school competition and player development: is aimed at increasing local opportunities for secondary school boys to play Rugby League, either for the first time or to assist in providing more regular opportunities for students at Key Stage 3 (year's 7 – 9 boys) to play. Linked to the competition delivery is the CPD workshops for secondary school teachers and community coaches U12-U14 that assist in further development of Rugby League and sustainability of the sport.
Sky Try Play Touch: is a 6 week touch workout project aimed at increasing the number of girls participating at Key Stage 3 and 4 (years 12 – 15) benefiting from an extraordinary participant experience.
Making the big games bigger: is targeted at increasing the number spectators at club matches and RFL major events through the Sky Try local projects.
The seven year partnership with Sky is a great opportunity for Rugby League to have a significant impact and make a difference.
The Sky Try Rugby League Programme is the test bed for future projects and will be delivered with rigorous governance that will have lasting impact on the sport in years to come.
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- From mobile
- Michaels
- Aug 07
- by anonymous
- #896091
The store in juban crossing in Denham springs Louisiana worse service ever for framing dept. no one is ever there takes weeks past date promised to get back. Management doesn't care. Never will step foot in the place ever again. Hobby lobby will have all my business now!!!Add comment


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Live updates
Philip Hammond condemns Turkey bomb attack
Foreign Secretary Philip Hammond has condemned the bomb attack in Istanbul which killed 11 people and injured a further 36.
Mr Hammond said on Twitter that his thoughts are with the victims of the "senseless and appalling act of violence".
Thoughts with the victims of today's #Istanbul bomb attack. The UK utterly condemns this senseless & appalling act of violence.
US ambassador to Turkey John Bass also condemned the "barbarous terror attack", and extended condolences to victims and their families.
Turkey's President Recep Tayyip Erdogan visited victims being treated in hospital today, and said the country would fight terrorists "to the end".
No-one has yet claimed responsibility for the attack, which occurred during rush hour in the central Istanbul district of Vezneciler.
It is the fourth major bombing in Turkey's biggest city this year.
First UK Foreign Secretary visit to Cuba since 1959
Philip Hammond has become the first British foreign secretary to visit Cuba since before the communist revolution of 1959.
Arriving in the capital Havana, Hammond said Britain was keen to forge "new links" with Cuba, and the two countries are "set to reach new cooperation agreements on energy, financial services, education and culture, to the benefit of both our nations".
His visit follows US President Barack Obama's historic visit last month intended to normalise relations between the two countries after decades of hostility.
- ITV Report
Hammond won't rule out sending troops to Libya
Foreign Secretary says it "wouldn't make sense to rule anything out" but says MPs would be given chance to vote on any proposed action.Read the full story ›
Hammond: No British combat troops to Libya
Foreign Secretary Philip Hammond has just addressed the Commons on the role British troops could play in the ongoing turmoil in Libya.Read the full story ›
- ITV Report
MPs want clarity over possible army deployment to Libya
Foreign Secretary Philip Hammond is being urged to make clear whether British troops will be sent to the strife-torn north African country.Read the full story ›
Hammond: Judge Russia withdrawal on actions not words
Foreign Secretary Philip Hammond has said Russia should be judged on actions not words as he awaited confirmation of its partial withdrawal of forces from Syria.
Mr Hammond told the Commons the international community had not received "independent evidence" of the downscaling of Russian forces
He said he would be "delighted" if the reports were verified but said no members of the International Syria Support Group were given advance notice of Mr Putin's surprise announcement and urged caution.
No one would be more delighted than me if, after five months of relentless bombing, Russia is genuinely winding down its military support to the brutal Assad regime.
But, as in all matters related to Russia, it is the actions rather than the words that count. We shall be watching carefully over the coming days to see if the potential promise of this announcement turns into reality.
- ITV Report
Philip Hammond: 'No credible alternatives to EU'
The Foreign Secretary warned a Brexit would cost the UK jobs and push up prices.Read the full story ›
Hammond: Legal basis for UK striking IS in Syria
There is a "legal basis" for Britain taking military action against so-called Islamic State in Syria, Foreign Secretary Philip Hammond said.
Hammond confirms Shaker Aamer Guantanamo release
Shaker Aamer, the last British resident held at Guantanamo Bay, has been released, Foreign Secretary Philip Hammond has confirmed.
"The Americans announced some weeks ago that they were going to release Shaker Aamer from Guantanamo," he said in Vienna.
"I can confirm that he's on his way back to the UK now and he'll arrive in Britain later today."
UK-Iran relations: Rebuilding historic ties
With the British embassy in Tehran open once again, the UK is beginning a process of re-engagement with Iran.Read the full story ›


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The Elder Scrolls V: Skyrim
- Boards
- The Elder Scrolls V: Skyrim
- Why do you play this on console instead of PC?
Lethalbutters 4 years ago#151
It won't budge.
theIllusionary1 4 years ago#152
Supernautus posted...
Because I want to.
There are two factors that influence how you view life: perception and reality. What you perceive is my illusion...the reality is that I'm already gone...
SandalFury 4 years ago#153
Aurawhisperer posted...
PC: This game is wayyyyyy better than the console! Makes the console look like some mini gimmick that is unstable for games such as this one!"
I'm pro-console, but this is one of the dumbest posts I've ever seen.
Headshot. Apply THAT directly to the forehead.
jrr18 posted...
I was kidding.
Sorry for exploding.
Nothing to see here, but the post below me sure looks suspicious.
ajko000 posted...
jrr18 posted...I was kidding.
no problem.
Victory through superior fire power!
PSN jrr101
Actually Ps3 is more powerfull then people give it credit. It just much harder to programm. The last of us and watchdogs that will be coming out already show promise to elevate it to the ranks of PC.
Also consoles are developing faster then PC. PC players get graphic cards every year that only slightly increase it's perfomance. Consoles come out once every 5 years and are 10times better. And once atomic graphic engine comes out PC will die as a gaming platform as it will no longer have excuse of better graphics. And when combined with ouya PC will have nothing and will be inferior.
Shaminardrgn 4 years ago#157
Simple answer: because I don't have a fast enough computer yet.
Once I do, you can bet that I'll go to town on the construction kit and make everyone who annoyed me pay very, very, very dearly!
Plus, I'll use all the tasty mods and texture enhancements to my satisfaction.
"If Ripto were here, I'd give him a piece of my mind!" : Moneybags from Spyro 2
charon78au 4 years ago#158
Yeah, because I want to.
Also FOR THE LOVE OF CHEESE, "THEN" AND "THAN" ARE TWO, COMPLETELY DIFFERENT WORDS. LEARN THEM!!!!!!!!!!!!!!!!!!!!!!!!!!!!
(Im)mature Aussie gamer. Don't pay the ferry man. Don't even fix a price.
GT: Charon78
PathlessBullet 4 years ago#159
Because PS3 has the power of the cell processor breh. Developers haven't even tapped into its full potential yet breh.
ADD, no. Where is the thread for Fallout OCD players?
"We have to keep it on page 3 or it freaks out."
DarkProtagonist 4 years ago#160
Can't afford/can't be bothered to buy/build a decent gaming PC.
"Ladies and gentlemen, if you've ever wondered how a war would be run by disorganised hippies, here it is." - RLM
- Boards
- The Elder Scrolls V: Skyrim
- Why do you play this on console instead of PC?
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The Abraaj Capital Art Prize (ACAP) announced the five winning artists for its fifth edition on 27 August 2012. Among them is first time Syrian winner, artist Hrair Sarkissian.Continue reading
Tag Archives: sculpture
Alserkal Avenue, an organically-grown, self-sustaining arts district in Dubai, is celebrating the opening of its annual art season on 10 September 2012.Continue reading
Starting in July 2012, a huge exhibition of new work by 52-year-old Japanese artist Yoshitomo Nara will travel to three museums in his home country.Continue reading
Upon its completion in 2014, the ambitious eighty hectare Yellow River Arts Centre will incorporate multifaceted facilities for research, education and leisure.Continue reading
Mongolian artist Munkhtsetseg Jalkhaajav, also known as Mugi, recently concluded her first solo exhibition in Hong Kong. Her works commonly depict women and deal with the re-emergence of Mongolian heritage.Continue reading
Eleven Asian artists have been included in the inaugural edition of La Triennale, which was launched at the Palais de Tokyo in Paris on 20 April 2012.Continue reading
Lachlan Petras was awarded the AUD35,000 Dr Harold Schenberg Art Prize at the 2012 "Hatched" National Graduate Show at the Perth Institute of Contemporary Art.Continue reading
"Ai Weiwei absent" wrapped up at TFAM on 29 January 2012 after a three-month-long run. Art Radar takes a look at its reception and the political questions surrounding the show.Continue reading