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Hotels in Seine-et-Marne (department), France
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Trending now in Seine-et-Marne (department)
- Most bookedExplorers Hotel at Disneyland® Paris
1,423 people looked at this hotel in the last hour
Most recent review
"Just got back from Explorers. Great base for Disneyland Paris. Went with Grandchildren who really enjoyed all the amenities. Rooms were cleaned everyday and public areas where kept clean. Breakfast was more than adequate. Didn't eat dinner at hotel as we were always at the parks. We did buy sandw..."
A Traveller, Sep 2016, GB
724 people looked at this hotel in the last hour
Most recent review
"Great hotel for a disney trip. Free shuttle every 30mins. Rooms were spacious and beds were comfy. Really good food but the drinks and food were very expensive. Nice indoor pool and sauna area."
A Traveller, Sep 2016, GB
564 people looked at this hotel in the last hour
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"Very nice hotel rooms very spacious and comfortable. Kids loved it. "
A Traveller, Sep 2016, GB
557 people looked at this hotel in the last hour
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"Good experience, Staff are so helpful and friendly "
A Traveller, Sep 2016, US
486 people looked at this hotel in the last hour
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"Positives - excellent hotel within a very short distance to Disney land Paris and the designer outlet. The hotel had great facilities including a pool & sauna, free WiFi and free shuttle bus too and from Disney. Negative - the apartment we stayed in was for two people and the only place to sle..."
A Traveller, Sep 2016, GB
332 people looked at this hotel in the last hour
Most recent review
"The staff was very friendly and helpful. We left our luggages at the hotel and went to Disneyland with free bus shuttle. The room was BIG compare to other hotel rooms in Paris city. There was AC so it was very comfortable. Only one thing that bothered me was the bathroom light switched off automa..."
A Traveller, Sep 2016, GB
- Relais Spa Val d'EuropeNo Guest Reviews yet
261 people looked at this hotel in the last hour
Most recent review
"Nice hotel. A few minutes away from the metro station, keeping me in touch with Disneyland and the airport. Recommended. "
A Traveller, Sep 2016, US
202 people looked at this hotel in the last hour
Most recent review
"It is a 35 minute ride from Paris by metro. There is a hotel shuttle in the morning and afternoon that takes you to the hotel from the station. Local bus #22 does also. There is a full spa and restaurant for all meals. Great deal especially for the price. So it's a great hotel at a very good p..."
A Traveller, Sep 2016, US
- Novotel Marne Vallee CollegienNo Guest Reviews yet
177 people looked at this hotel in the last hour
Most recent review
"I will definitely go back to the hotel. The staff, food, rooms and the outdoor activity is excellent. I love the gym, swimming pool, badminton court, table tennis court and the basket ball. Good service and very helpful staff. "
D, Sep 2016, GB
108 people looked at this hotel in the last hour
Most recent review
"Extremely handy for visiting Disneyland - 30 seconds from the train station. Great room, friendly, English speaking staff."
A Traveller, Sep 2016, GB
Map of Seine-et-Marne (department) hotels
- La Vallee Outlet Village
- Val d'Europe Shopping Center
- Golf Disneyland® Paris
- Chateau de Vaux-le-Vicomte
- Parc des Felins
- Chateau de Fontainebleau
- Val d'Europe Business Center
- La Ferte-Gaucher Racetrack
- Aquarium Sea Life Paris
- Centrex
- Centre Commercial les Arcades
- Fontenailles Golf Club
- Clement-Ader Golf Club
- Montereau-Fault-Yonne Park
- Fontainebleau Golf Club
- Bay 2
- Bussy-Guermantes Golf Course
- Cely Golf Club
- Church of Montereau-Fault-Yonne
- Saint-Martin-des-Champs Priory
Best hotels in Seine-et-Marne (department)
If you are looking for Seine-et-Marne (department) hotels in a particular area, you can use the search feature at the top of the page to search by neighborhood, landmark, address or zip code, or you can search by using the built-in map feature. You can also browse hotels in Seine-et-Marne (department) by type, amenities, and star-rating so that you can find the best hotel. Currently, top rated hotels in Seine-et-Marne (department) are:
- Hôtel de Londres
- La Briarde Médiévale
- La Demeure du Parc
- Marriott Village d'Ile-de-France
- Château de Bourron
The location of your Seine-et-Marne (department) hotel is important. If you are traveling to Seine-et-Marne (department), &StateorCountry for business, you may want to consider getting a hotel close to the airport or near your meeting venue. By doing so, you can really cut down on transportation costs and time. You may also want to book a hotel that offers free wifi just in case you need to get some work done.
If you are traveling for vacation, figure out which attractions or landmarks you want to see and book a hotel that is within close proximity. Although hotels near attractions might cost a little more, you may find that spending those extra few dollars is worth the convenience. You can even find hotels that align with your interests. For example, if you are looking for a relaxing vacation, a spa hotel may be the perfect choice for you.
You'll also want to determine which type of accommodations will suit your needs before booking a hotel in Seine-et-Marne (department). If you're traveling with the kiddos, a family friendly hotel will offer larger rooms and more sleeping arrangements. For those traveling for an extended period of time, booking a hotel suite with a kitchenette is a smart move and will feel a little more like home. If you are budget conscience and just need a place to rest your head, a hostel or motel may be all you need.
If you are looking to score the best discounts and deals, use the filter to sort by price from low to high. You can book a hotel in Seine-et-Marne (department) for as low as $30 per night. If you are looking to cut down on expenses, look for hotels that include free breakfast and parking. Some hotels even offer free shuttle service to and from nearby places. You can also sort by star rating, proximity, and guest rating.
Before you book, check out user reviews. Hotels.com has 33539 reviews in Seine-et-Marne (department). We show reviews from Expedia and TripAdvisor so you know that you are reading genuine, reliable reviews. Be sure to download the Hotels.com app so you can book your reservations on the go, view amenities, and save the hotels you want to view and compare later.


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subset: commoncrawl


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Conservationists Discover Cave Art in Brazil
Friday, November 08, 2013
BRONX, NEW YORK—While she was conducting a survey of white-lipped peccaries in 2009, Alexine Keuroghlian of the Wildlife Conservation Society found drawings of animals and geometric figures in sandstone caves on Brazil's Cerrado plateau. She contacted archaeologist Rodrigo Luis Simas de Aguiar, who determined the drawings were made by hunter-gatherers between 4,000 and 10,000 years ago. Some of the drawings, which depict armadillos, deer, large cats, birds, reptiles, and human-like figures, resemble drawings of the central plateau, but others are similar to images usually found further north. Excavation of the cave floor and geological dating could provide more information about the artwork.
Kennewick Man's roots, rise of the Wari Empire, turtle soup, hyenas vs. humans, and an ancient Chinese beer recipe


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Kentucky basketball coach John Calipari covered the two hot topics today: Ryan Harrow's health (and playing status) and Morehead State coach Sean Woods' controversial comments yesterday about the Cats. As for UK's players, Kyle Wiltjer and Jarrod Polson said they really hadn't heard about what Woods, the former Wildcat, said (that they seemed entitled and didn't appreciate the history of the program). Senior Julius Mays' reaction: "I don't think he's been around us enough to judge." Mays said Kentucky's heralded freshmen are all out to prove themselves and don't seem entitled to him at all. Wiltjer noted that most of the currents Cats come from all over the country and had no reason to know the detailed history of UK's program, but once here, "they respect it."
I'll post more from the players later. Also, Sean Woods is scheduled to speak to the media before Morehead's practice tonight at Rupp Arena, so I'll have those comments, too. For now, here's everything Calipari said before the Cats' practice this afternoon:
ON RYAN HARROW'S STATUS: "I guess better. He's at an academic meeting. He'll be at practice today. But I guess better. He's lost weight. He's got to get some weight back (and we'll) see from there."
ON WHAT WAS WRONG WITH HARROW: "They don't know. All they're saying is he's lost seven pounds and must have had something going on. They don't know what it was. But we will see."
ON HARROW NOT HAVING MUCH WEIGHT TO LOSE: "No. He looked thin. He looks thin. That's why I said, I don't know. I want to see him in a practice setting and start figuring out what we do, what's the timetable."
ON SEAN WOODS' COMMENTS: "At the telethon and whatever these guys have done, they were hugging volunteers, so I don't know where he got that. Maybe someone didn't know him or something. I don't know. But I love what our kids are about, what they've done academically, what they do in the community. Being here is a big deal. It's hard to deal with all the stuff that goes around, but these guys seem to do it pretty well."
ON IF HE WAS UPSET OR DISAPPOINTED: "Somebody hit me (with the comments). You guys know I don't deal with all that stuff. Someone said something to me about it, and I just said, 'What?' All right, I need some more tape anyway."
ON IF WOODS' COMMENTS WERE DISAPPOINTING BECAUSE CALIPARI HAS WELCOMED IN FORMER PLAYERS: "Knowing Sean, I figured he misspoke. I chalk it up to that, and I move on. I'm not taking it personal. Our kids, you may have talked to them, I bet you half of them didn't even know he said anything. Look, this program, you know how much is said about this program and me personally? Oh my gosh. You'd think I look like that (makes devil horns with his fingers). I mean, I don't listen to it. Then the other stuff is I walk on water. Guess what? I don't. I'm a regular guy, a sinner like everybody else. I try to do my job. I don't buy into all that stuff. Say what you want, 50 years from now people will evaluate the jobs we've done, where we've been and that's all I can count on."
ON IF KYLE WILTJER IS STARTING TO DO MORE OF WHAT HE WANTS: "Little bit. He shot the ball really well two days ago. He practiced half of practice yesterday, but he'll be fine."
ON IF THEY ARE READY FOR MOREHEAD DEFENSE, WHICH FORCES AROUND 20 TURNOVERS A GAME: "We're not. We're not prepared. They'll scramble, and if the game is allowed to be physical, they'll turn us over a bunch. But it's what we need. It's not how much have we worked on press attack. We're still trying to get them to play hard. We're trying to get them to play a full possession. We started working on situations yesterday, yesterday. That was just very average, what we did. So, we've got to continue from this point on working on all some specialty things, but we still have the basics we've got to get better at. The only way you create habits is do something every day. Well, if you do everything that we have to improve on every day, we'll have a nine hour practice. So, we are where we are right now."
ON IF HARROW'S ABSENCE HELPED BUILD DEPTH THAT WILL LATER HELP THE TEAM: "Yeah, but I'd rather have him. That stuff gives guys an opportunity. Any time you have injuries or things of that nature, things happen on your team. Maybe you didn't know or you're surprised, but the reality of it is you'd rather go through without that kind of stuff."
ON HOW MUCH GROUND HARROW HAS TO MAKE UP: "He's obviously the low man on the totem pole. You've gotta start from behind. That ain't all bad for him either, because now he's going to have to fight for time. He's behind everybody, which means you've got to earn it in practice. It's not all bad."
ON WHETHER MOREHEAD PLAYS A STYLE THAT UK NEEDS HARROW MORE: "Doesn't matter. We need to be pressed and played physical and let's see what we're about, if we'll be strong with the ball, if we're going to come to jump stops, if we'll come back and meet passes, if we'll make the extra pass. We'll find out. This is all learning. We could have 30 turnovers and they beat our brains in. It could happen. We're a young team. We don't even know how we're going to respond to stuff."
ON THE SOUTHEASTERN CONFERENCE SO FAR: "I'm really not following scores. Folks, I don't have time to do anything except try to coach my team, so I don't know. I know what our record is, I believe. What is it, 2-1? Okay. Other than that, I don't know anybody, who they've played, how they've done. I've not watched one second of our league right now. I haven't. At the end of the day, we're going to have five, six, seven teams right there with a chance to be in the NCAA Tournament and advance. We've had a team in the Final Four four of the last seven years, I think, or eight years, we've had a team in the Final Four. The league is fine and they'll be fine. I wish them well unless they're playing us (and then) I hope they get smashed."
ON, GIVEN THE 20-HOUR-A-WEEK PRACTICE LIMITS, HOW MUCH FURTHER ALONG THIS TEAM WOULD BE IF IT HAD A BETTER MIX OF VETERANS: "We don't ever go 20 hours anyway, but we would be obviously farther ahead because I would be able to teach them through watching their teammates. In other words, I don't have to do it myself, walk through it, stop it, do it again, do it again, do it again. They could watch a teammate do it, then they mimic that. 'Do what he just did,' and then they do it. But this is different."
ON SAYING AFTER LAST GAME THAT NERLENS NOEL'S EFFORT COULD EMBARRASS OTHER GUYS INTO PLAYING THAT HARD, AND WHETHER HE'S SEEN THAT: "No. No (grinning). But Willie (Cauley-Stein) got mad because he said, 'I'm an energy guy, too. I've just been sick.' OK, I'll be watching."
ON WHETHER HE'S CLOSER TO FIGURING OUT HOW THIS TEAM WILL PLAY: "No, because we've got to get through games and play people. The Duke game we learned some stuff. Maryland, we learned some stuff. Lafayette, we learned some stuff. Now we've put in our presses. We just put them in. So now we have our presses, two of our presses in. They're not very good, but they're in. So now we can press. Couldn't press before. We have some zone stuff in, so both the zone defense and zone offense. So now, it's not very good, but we can do it. Our press attack is in; it's not very good, but it's in. And now we've got to find out what we like about what we're doing and what we'll change. You just, you put it in, you go with it; if you like it, fine; if you don't … We're playing different than we played a year ago. I like my team, but this will be a great test. They're all teams that are different, and that's what we need."
*For instant updates on the Wildcats, follow me at twitter.com/KyleTucker_CJ.


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This awkward middle volume, the second installment of Ruckley's Godless World trilogy (after 2007's acclaimed Winterbirth), lacks the thematic impact and emotional intensity of its predecessor. As the armies of the Black Road, a fatalistic religious movement revolving around a creed of predestination, descend from their northern exile, the quarrelsome leaders of the True Blood clans must join forces or die, but supernatural forces beyond their understanding are playing with their destiny. Multiple plot threads featuring dozens of integral characters bog down the pacing considerably, creating a narrative that, like the unwieldy and poorly led True Blood army, becomes a "lethargic thing" emanating "resentment and reluctance." New readers will be utterly lost and fans left impatient for book three. (June)Copyright © Reed Business Information, a division of Reed Elsevier Inc. All rights reserved.
Bloodheir (Godless World Series #2)by Brian Ruckley
View All Available Formats & Editions
The world has fallen from its former state. The war between the clans of the Black Road and the True Bloods has spread.
For Orisian, thane of the ruined Lannis Blood, there is no time to grieve the loss of his family, brutally slain by the invading armies. The Black Road must be stopped. However, as more blood is spilled on the battlefields, so each side in the
The world has fallen from its former state. The war between the clans of the Black Road and the True Bloods has spread.
For Orisian, thane of the ruined Lannis Blood, there is no time to grieve the loss of his family, brutally slain by the invading armies. The Black Road must be stopped. However, as more blood is spilled on the battlefields, so each side in the conflict becomes more riven by internal dissent and disunity.
Amidst the mounting chaos, Aeglyss the na'kyrim uses his new-found powers to twist everything and everyone around him to serve his own mad desires.
Meanwhile, the long-dormant Anain are stirring - and when the most potent race the world has ever known returns, the bloodletting may never stop.
BLOODHEIR is the stunning sequel to Winterbirth, one of the most acclaimed epic fantasy debuts of recent years.
Editorial Reviews
Following his fantasy debut, Winterbirth, this middle book of the "Godless World" trilogy reimmerses readers in the Clans-and-Indians atmosphere of Ruckley's heroic fantasy world. The titular "bloodheir" could refer to any of three candidates. Orisian, newly minted as thane of the Lannis Blood, searches for a positive direction in which to lead his staggered people. Aewult, the Haig prince and Orisian's ally, commands a huge army, but his arrogance and greed for glory may doom them all. And Orisian and Aewult's mutual foe, Aeglyss, channels the rejections of his youth into a horrible magical vengeance as his strange powers mutate, raising him ever higher in the fatalistic ranks of the Black Road as they bring war deep into Haig lands. Or it could be that the bloodheir is actually the reader, who will learn that no secondary character is safe in Ruckley's cruel, icy world. This grim, sometimes gripping martial epic will leave those who have come this far anxious for the final chapter. A solid fantasy choice, especially for libraries where Winterbirth found an audience.
Neil Hollands
Product Details
- 9780316068079
- Publisher:
- Orbit
- Publication date:
- 04/01/2009
- Series:
- Godless World Series , #2
- Edition description:
- Reprint
- Pages:
- 656
- Sales rank:
- 466,420
- Product dimensions:
- 4.20(w) x 6.90(h) x 2.20(d)
Meet the Author
Brian Ruckley was born and brought up in Scotland. After studying at Edinburgh and Stirling Universities, he worked for a series of organizations dealing with environmental, nature conservation and youth development issues. He lives in Edinburgh. Find out more about Brian Ruckley at www.brianruckley.com.
Customer Reviews
Average Review:
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Most Helpful Customer Reviews
See all customer reviews >
Even though this book has different races each with their own characteristics, it does not delve into a world filled with magic. For the most part it keeps things very human and realistic.
Long and drawn out... but not boring! Lots of death, destruction, misfortune, deception, betrayal, fighting, manhunting, and war. You'll come to respect certain characters and love others. I can't even (honestly) disrespect the bad guys in this book, because their cause seems so righteous! I'm glad I stumbled into this series, can't wait to read "Fall of Thanes" which is book number three.
Good 3D characters. Complex plot. A good solic read.
Orisian has become the Thane of the Lannis Blood at a critical time with his people reeling from recent events (WINTERBIRTH) he is unsure of what to do to turn things around on their frozen land, but thirsts to save his people.---------------- At the same time his friend Haig Prince Aewul leads a tremendous military force, but avarice and the thirst for glory could prove their undoing if not checked by rational thinking.------------------ Their adversary Aeglyss seeks magical revenge on his enemies even as his thirst enables him to rise towards the top of the dangerous Black Road he plans to bring the fight to Haig and Aewul before dispatching Orison.------------------------ The second Godless World epic fantasy is bloody grim as Brian Ruckley continues to vividly paint an extremely dark realm. The story line is fast-paced and filled with non- stop action that traverses much of the Godless World. Yet the key to this excellent fantasy is the cast as the three leaders play a deadly game of chess in which checkmate does not necessarily mean victory or defeat because cunning can change the rules of engagement. Orisian is especially fascinating as he understands war means death, destruction, and chaos with no true victors yet cannot prevent it from coming. Readers who enjoy a powerful enthralling fantasy thriller will appreciate Brian Ruckley's aptly named BLOODHEIR.-------------- Harriet Klausner


text:
There are a few reasons I chose this video for today's edition of The Amateur Hour—1) It's still technically Bear Week in Provincetown, 2) I'm a sucker for guys with mustaches and big beefy asses, 3) That hairy hole drives me absolutely wild, and 4) The aforementioned mustache, big beefy ass and hairy hole reminds me of a guy I used to meet at a local gay bar and fuck at a sleazy motel when the night was over.
There's got to be an interesting story behind this video, right? I'd like to imagine that these two are a married gay couple who met on Manhunt, engaged in some trucker role-play, and now they're recreating the first night they met on their anniversary. The real story probably isn't that precious, but oh well, a boy can make up his own cute stories if he wants to…
– Dewitt
Watch the thirteen minute amateur video clip below:
Copyright © 2008-2016 Manhunt Daily a product of Online Media LLC. All Rights Reserved.


text:
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September 21, 2016
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The best beauty advent calendars for 2015
Here's why we're ditching morsels of chocolate for beauty treats this year
Ok so let's admit it – a definite highlight of December is waking up to a sneaky bite of advent calendar chocolate with our cup of tea. But, imagine having the delight of a little present every day in the form of a beauty product. Have we got your attention? This year, all our favourite beauty names are hauling out their ever-popular calendars in the countdown to Christmas. Ranging from small bottles of perfume to little pots of cream blush, there's pretty much something for everyone. Now we've got the hard task of deciding which one to go for, and more importantly, who to ask. Feast your eyes, girls…
Clarins, £60
The great value offering from Clarins is packed full of iconic beauty buy, from their Beauty Flash Balm to the Instant Eye Make-Up remover – and there's even some treats for the boys (hello free stocking fillers!).
Available now at Clarins.com
Eylure, £50
Want to add some vintage Hollywood glamour to your festive outfit? Well, Eylure's '12 days of lashes' advent calendar is just what you need! Each of the 12 movie reel doors hides a lash inspired by a different iconic actress and era from 1948 to 1970 – don't worry they've also included a full sized glue to help you apply these beauties with ease.
Available exclusively at eylure.com now
Essence, £24.99
This calendar is perfect for any Essence nail polish lover and includes 24 limited edition nail products as well as a 'quote of the day' behind each door! The mini gifts include a cosmetic bag, 39 metallic nail stickers, 2 mini nail files and 20 nail polishes and top coats with effects such as matte and shimmering - all 5ml each!
Available exclusively at Wilko stores and wilko.com now
Avon, £55
Worth £78, this bargain for nail lovers contains 12 polishes in a rainbow of shades and topcoat effects – all a decent 10ml each.
Available via the Avon brochure and online from 12th November
Diptyque, £250
Candle fans, be still your beating hearts – this one's pure luxe. Containing 15 mini candles and one big boy, plus seven 10ml Eau de Toilettes, a 15ml Rich Body Butter and Precious Oils, it's quite something.
Available at Selfridges from mid-November
Kérastase, £80
Hair lovers, the first ever luxury advent calendar from Kérastase is set to transform your tresses. The perfect girlie house share gift, it contains 25 travel, mini and full size products for all hair types, including some icons. We want it.
Available on 1st November at kerastase.co.uk
Benefit Cosmetics, £34.50
Not only does each of its 12 doors reveal one of Benefit's many cult classics, the set opens to a festive song! So if you're looking for a bit of everything to add to your makeup collection, this one is bound to please. We'll be popping the lip gloss minis in our handbags for party season.
Available at debenhams.com and benefitcosmetics.co.uk from 15th October and nationwide from November
No7, £38
This have-it-all advent calendar has a selection of beauties from skincare to cosmetics, bathing bits and accessories – and six products are full-sized. Worth a whopping £148, it's only £38. Bargain.
On sale 28th October at Boots and boots.com
M&S Beauty, £25*
Filled with 24 festive treats worth over £200, you can buy the M&S Beauty Advent Calendar for £25 *when you spend more than £25 in M&S Beauty. Nifty! It includes treats from some amazing brands such as Rodial, Neal's Yard, REN, Stila and Cowshed.
Available from November at Marks & Spencer nationwide
Ciaté, £49.99
Need a new manicure to match every outfit over party season? Fear not - Ciaté has promised to meet all your nail demands with its Mini Mani Month. Equipped with 18 different colours, the collection also includes treatments to keep nails in ship shape. We've got our eye on the red from the exclusive Olivia Palermo X Ciate collection. Oo la la.
Available at Selfridges, ASOS, Boots, Look Fantastic and Very
CHEEKY Advent Calendar, £49
With 24 on-trend tones, the CHEEKY Christmas Advent Calendar is another nail junkie's dream.
Available at Cheeky Holborn, Cheeky at Barber & Parlour, Cowshed Spas and urcheeky.com
Lush, £49.95
Calling all natural, homemade product fans – Lush has created a calendar filled with its famously fragrant shower and bath treats to lather up in the lead to Christmas. Start running that bath…
Available at Lush shops and at Lush.co.uk nationwide from 2nd October
Liberty, £149
Liberty makes us feel festive simply because of its ever-luxurious prints and luxury product range. So feast your eyes on this treat, it may be a splurge at £149 but if you feel like treating yourself this Christmas (or getting others to do so) it's a winner. Also with brands ranging from Decleor and Kiehl's to Trish McEvoy –what's not to love?
Available at Liberty from 29th October
Jo Malone, £260
Jo Malone has gone to town this Christmas (and not only in its uber pretty Georgian townhouse design) – this decadent collection contains both mini perfumes and scented body creams. So if you're a perfume fanatic and can't decide on one to put on your Christmas wish list, this is perfect.
Available at Harrods from October and nationwide from November
The Body Shop, £60/£80
The Body Shop has catered for different budgets with two versions of its calendar this year. The standard version saves you more than £30 while the luxury version will save you a whopping £47 compared to if you brought the products individually. Treats include favourites from their skincare, bath & body, fragrance and makeup ranges.
Available at The Body Shop from late October
L'Occitane, £39
Unlike last year's '12 days of Christmas' offering this year the French beauty brand has upped their game and now have 24 mini versions of their luxurious skincare, hair, and body products to delight from. Joyeux Noël, indeed!
Available at L'Occitane boutiques and online from 21st October
Charlotte Tilbury, £150
Our fave makeup artist just keeps coming back with more; The Book of Make Up Magic includes mainly her best-selling hero products, and is a mix of both travel size and full sized products. Since we can't decide what to buy first, this is a dreamy treat for any makeup (and Charlotte Tilbury) obsessive.
Available exclusively at CharlotteTilbury.com, Selfridges, Selfridges.com and Brown Thomas
House of Fraser, £20
Featuring its own-brand 'Colour Couture', House of Fraser has included something to literally build a make-up kit from scratch. We like this one for its extremely reasonable price tag, and for the fact it has a bit of everything to get you through the season.
Available at House of Fraser from September
Selfridges, £95
A bit like a mini shopping spree round one of our ultimate beauty halls, this luxury advent calendar includes surprises from brands such as Kiehl's, Lancome, YSL, and Victor and Rolf. Now that's a shopping trip we like the sound of!
Available exclusively at Selfridges, and Selfridges.com from Mid-October
We all know W7 is one of the best value bargain beauty brands – and this is the ultimate selection of their offerings in one hit. The 24 treats include mini glitter pots, glosses, lipsticks and shadows – plus the Absolute Lashes mascara. All for just £23.95.


text:
Rent Hip-Hop U.S. History 1st edition today, or search our site for other textbooks by Blake Harrison. Every textbook comes with a 21-day "Any Reason" guarantee. Published by Cider Mill Press.
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Now showing items 81-90 of 745
Monitoring the Norwegian Atlantic slope current using a single moored current meter
(Elsevier, 2003-01)
Monitoring the Atlantic inflow (AI) of warm and saline water into the Nordic Seas (Norwegian, Greenland and Iceland Seas) is of great importance becauce of its impact on climate and ecology in Northern Europe and Arctic. ...
National Versus International Mergers in Unionised Oligopoly
(Stein Rokkan Centre for Social Studies, 2004-12)
We analyse how the presence of trade unions affects the pattern of mergers in an international oligopoly and the welfare implications thereof. We find that wages for the merger participants are always lower when they ...
NAV i støpeskjeen. En studie av NAV-reformens interimsfase, 2005–2006
(Stein Rokkan Centre for Social Studies, 2009-09)
The report studies events that took place between May 2005, when the Norwegian parlament decided to reform the Norwegian welfare administration, and June 2006, when the new state agency called NAV was established. The ...
Administrative Reforms and Competence in Central Government Organizations
(Stein Rokkan Centre for Social Studies, 2008-06)
This paper focuses on administrative competence in the Norwegian central government and its relationship to administrative reforms. Four different types of competence are addressed: Fachkompetenz, policy advice skills, ...
Better mental health in children of Vietnamese refugees compared with their Norwegian peers - a matter of cultural difference?
(BioMed Central, 2009-10-21)
Background: There are conflicting results on whether immigrant children are at a heightened risk of mental health problems compared with native youth in the resettlement country. The objective of the study: To compare the ...
Genome-wide transcription analysis of histidine-related cataract in Atlantic salmon (Salmo salar L)
(Molecular Vision, 2009-07-09)
Purpose: Elevated levels of dietary histidine have previously been shown to prevent or mitigate cataract formation in farmed Atlantic salmon (Salmo salar L). The aim of this study was to shed light on the mechanisms by ...
Norwegian farmers' diaries used for quality control and calibration of early instrumental observations, and for temperature reconstructions
(The University of Bergen, 2008-06-10)
Roma – en midlertidig døv by! Deaflympics 2001
(Stein Rokkan Centre for Social Studies, 2002-06)
Tekstene i denne publikasjonen, Roma – en midlertidig døv by, bygger på feltarbeid i Roma, sommeren 2001, hvor de Døves verdenslekene (Deaflympics) ble avholdt. Dette feltarbeidet er det første i en rekke med feltarbeid ...
Crude oil components with affinity for gas hydrates in petroleum production
(The University of Bergen, 2007-06-28)
Some crude oils are believed to contain natural inhibiting components that can prevent hydrate plugging of oil pipelines in petroleum production. A method for classification of the oils that form hydrate plugs, as opposed ...
Evaluering av PMTO-kurs for fosterforeldre - en effektstudie
(Barnevernets utviklingssenter på Vestlandet, Unifob helse, 2009)


text:
Originating from KPFK 90.7 FM in Los Angeles, The Jimmy Dore Show is an irreverent and humorous take on today's headlines and hypocrites. The program skewers politicians as well as the corporate mouthpieces which make up today's mainstream "news media." Each and every week, The Jimmy Dore Show provides the unvarnished truth with a twist of funny.
Don't forget to subscribe, donate, and review the show on iTunes!
The Jimmy Dore Show podcast may 20, 2016The_Jimmy_Dore_Show_5-20-16.mp3
More Stuff Happened & We Make Fun Of It!
Ron Paul opens the show talking about Trumps economic plans.
We take an in depth look at the chaos at the Nevada State Caucus, and the bogus new reports of violence by Bernie supporters.
With Mike Macrae, Jim Earl, Stef Zamorano, Robert Yasumura
The Jimmy Dore Show podcast may 13, 2016The_JImmy_Dore_Show_5-13-16.mp3
More Stuff Happened & We Make Fun OF It!
Bernie Sanders gave a stern dressing down to to a smug and condescending Alan Greenspan in 2003, only 5 years later Greenspan was back admitting his theory of economics was BOGUS.
Andrea Mitchell, does the opposite of journalism when interviewing Bernie Sanders. Nobody notices.
Workers at chicken processing plants in the US have aren't allowed bathroom break and have to wear diapers on the production line.
Pres Obama & Sen Sanders call in.
Mourning remembrance with Jim Earl!
With Stef Zamorano, Mike MacRae,
The Jimmy Dore Show Podcast 5-6-2016The_Jimmy_Dore_Show_5-6-16.mp3
More Stuff Happened & We Make Fun Of It!
Reince Priebus calls in to open the show and share his tale of wow inside RNC headquarters.
Turns out Wall Street Banks are only profitable because they get 83 billion a year in Government Welfare?
CNN does a 180 and now says that Hillary won't be able to work with Republicans! in congress?!?!
Ted Cruz encourages crowd to beat child protester.
Bill Oreilly & Ted Cruz call in!
With Mike MacRae, Robert Yasumura, Hank Thompson
The jimmy Dore Show podcast april 29, 2016The_Jimmy_Dore_Show_4-29-16.mp3
More Stuff Happened & We Make Fun Of It!
Andrew Jackson calls in to talk about his removal from the $20 bill.
Dennis Hastert, former GOP speaker of the house, is a SERIAL CHILD MOLESTER, and the pretend party of Family Values.
CNN spends way more time promoting Fossil Fuels than reporting on Climate Change.
Bernie Sanders Calls!
With Mike MacRae, Stef Zamorano, Robert Yasumura, Hank Thompson
The Jimmy Dore Show podcast april 22, 2016The_Jimmy_Dore_Show_4-22-16.mp3
More Stuff Happened & We Make Fun Of It!
-George Clooney calls in to explain his $353,000 a couple event with Hillary.
-We break down Clooney's interview with Chuck Todd.
-Peter King said that he would rather take cyanide than vote for Ted Cruz, he calls in to explain.
-Chris Hardball pushes same old stupid narrative that Bernie doesn't know how congress works.
-Jim Earl reads Ted Cruz's future obituary.
-LIAM NEESOM calls in!


text:
Annual General Meeting
Your Annual General Meeting is on Saturday 22 October 2016 at the STEAM Museum in Swindon. You can attend in person or online via our live broadcast. We'll be celebrating the many successes of the year and discussing some of the challenges we faced.
Look out for your AGM booklet which accompanies your autumn magazine. It contains information about two members' resolutions and details of your candidates seeking election to the Council.
The latest Annual Report and Financial Statements are available here.
Please use your vote
Come along or watch the webcast
If you want to get in touch about the AGM please contact firstname.lastname@example.com or call 01793 817663.


text:
Wall Street Decline Takes Its Toll...
Developers of DTC Genetic Testing Are...
Expanding Use of NGS Has Largely...
As Immunotherapy Revolutionizes the Cancer Treatment...
VTT Technical Research Centre of Finland and Deinove are joining forces to progress research efforts in biofuels and green chemistry. Deinove is focused on exploiting the natural properties of Deinococcus bacteria for the production of biofuels and other compounds of industrial or pharmaceutical interest.
Ten VTT researchers will team up with the company and its French academic partners from CNRS and INSA to leverage the properties of Deinococci in the digestion of biomass. They will also work on the development of an integrated process for the bioproduction of ethanol and chemicals from renewable feedstocks.
The objective is to evaluate different Deinococcus candidate strains screened by Deinove for deinol cellulosic ethanol production process. This process will then be scaled-up and tested in an industrial pilot by the sugar company Tereos.
"VTT is especially renowned for its expertise in enzyme discovery and engineering, with over 25 years of experience with lignocelluloses-degrading enzymes such as cellulases, hemicellulases, and other key-catalysts for the production of chemicals from biomass sugars," according to Deinove CEO, Jacques Biton. "In addition, VTT has cutting-edge skills and infrastructure for performing R&D in metabolic engineering, synthetic biology, and fermentation processes."
Erkki KM Leppävuori, president and CEO of VTT, adds, "As an open-innovation center creating sustainable industrial solutions, we are delighted to contribute to a future industrial breakthrough that could pave the way for many valuable developments not only in biofuels but also in the forestry and paper industry, the chemicals sector, and other markets."
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text:
|Publication number
|Publication type
|Publication date
|Dec 29, 1970
|Filing date
|Apr 15, 1968
|Priority date
|Apr 25, 1967
|Also published as
|Publication number
|Hrdina Jiri
|Original Assignee
|Ceskoslovenska Akademie Ved
|Export Citation
|BiBTeX, EndNote, RefMan
|Referenced by (5), Classifications (11)
|External Links: USPTO, USPTO Assignment, Espacenet
Dec. 29. 1970 METHOD OF AND 'AN AP 'J HRDINA rA'nATus FOR CHROMATOGRAPHICALLY :EPARATING AMINO ACIDS MIXTURES Filed April 15, 1968 JIRI HRDINA INVEN' )R.
United States Patent 3,551,107 METHOD OF AND AN APPARATUS FOR CHROMATOGRAPHICALLY SEPARAT- ING AMINO ACIDS MIXTURES Jiri Hrdina, Prague, Czechoslovakia, assignor to Ccskoslovenska akademie ved, Prague, Czechoslovakia Filed Apr. 15, 1968, Ser. No. 721,455 Claims priority, application Czechoslovakia, Apr. 25, 1967, 3,003/ 67 Int. Cl. B01d15/08; Gtlln 31/08 US. Cl. 23-230 3 Claims ABSTRACT OF THE DISCLOSURE A method of and an apparatus for chromatographically separating amino acid mixtures, and more particularly of separating the amino acid pair of tyrosine-phenylalanine, provides one or a plurality of chromatographic columns, wherein at first both acidic and neutral amino acids are eluted by one or preferably more citrate buffers until the elution of the amino acid of leucine, and thereafter the amino acid pair of tyrosine-phenylanine is eluted .by another buifer of which the pH-value of the normality are increased by leaps relative to the respective values of the firstmentioned buffer. The set of chromatographic columns is fed from a plurality of eluent reservoirs by means of a pump drawing the respective eluents selectively over a branched valve to the column and supplying it simultaneously with a specimen substance. The eluate to be evaluated is led from the column to an evaluating instrument over a capillary reactor, the evaluating instrument being fed with an evaluating agent by means of another pump withdrawing said agent from a reservoir.
BACKGROUND OF THE INVENTION It is already known that by adding some organic solvents, especially methanol, or any other alcohol with a short carbon chain therein, such as, for instance, n-butanol, it is possible to improve the separation of the amino acid pair of theeonine-serine which has been a critical pair in chromatographic amino acid separating processes. The aforementioned admixture of organic sol vents is, however, liable to change relative chromatographic positions of other amino acids than threonineserine; some amino acid pairs are affected to such an extent that the realtive separation thereof is aggravated. Thus, for example, the adding of methanol, or other organic solvents to improve the separation of the pair threonine-serine from each other is accompanied by an aggravated separation of, e.g., the pair of glycine-alanine so that the lastmentioned pair may become critical.
Further, it is well known to add methanol to elution buffer solutions in a chromatographic system comprising a single column for separating amino acid mixtures from each other, which column is filled up with a polystyrene cation exchanger,and eluted with a buffer solution having a continuously variable composition. The change in the elution buffer composition is ensured by a hydrostatic mixing device. The aforementioned undesirable effect of the alcohol admixture upon the amino acid pair of glycinealanine, or, perhaps, on other amino acid pairs is, apart from a positive effect on the separation of the amino acid pair of threonine-serine, manifested undesirably as soon as the threonine-serine pair has been excluded from the column; nevertheless the separation of other amino acids, including the glycine-alanine pair, proceeding on the column after the threonine-seriue pair has been excluded therefrom, is influenced by a certain alcohol admixture concentration. Moreover, the undesirable effect of the alcohol admixture resides in that the latter is, in certain concentration, present in ion exchanger grains even after the elution buffer solution has stopped contributing to or maintaining the alcohol admixture concentration in the ion exchanger grains. Even though the alcohol admixture is only contained in the first, or in a number of beginning chambers of the hydrostatic mixer on starting the chromatographic process. I must admit that by using such known process it is possible to attain the maximum positive effect upon the threonine-serine pair on the start of the elution, but in further course of the chromatographic reaction this effect is undesirable, since the hydrostatic mixing device does not enable a steep decrease gradient of the alcohol admixture concentration up to the zero value during the elution. Thus, the hydrostatic mixing devices do not limit the alcohol admixture effect strictly to the starting chromatogram phases, wherein said admixture cannot undesirably affect the other amino acids, especially the glycine-alanine pair, etc.
The purpose of the present invention and the basic object of the same is to overcome the aforementioned disadvantages and to significantly improve the chromatographic separation of amino acid mixtures.
SUMMARY OF THE INVENTION In accordance with one feature of my invention I provide a method of chromatographically separating amino acid mixtures, which comprises first the eluting of both acidic and neutral amino acids by one, or preferably more citrate buffers, up to the elution of leucine, and secondly the eluting of the amino acid pair tyrosine-phenylalanine by another buffer, the pH value and the normality of which are increased by leaps, i.e., by rapid or sharp transitions relative to the respective values of the first mentioned buffer.
An apparatus for carrying out the method according to the present invention comprises one or more chromatographic columns. The upper seal of the vertical chromatographic column is connected to the outlet portion of a pump, of which the inlet portion communicates in turn via a pipe with a branched or multi-way valve. Said branched valve is provided with inlet necks circumferentially arranged and connected to an eluent reservoir as well as to a vessel containing a specimen substance to be evaluated, respectively. The lowermost part of the chromatographic column communicates via capillary reactor with an evaluating device. The pipe connecting the lowermost part of the chromatographic column to the capillary reactor is, before having reached the reactor, branched to another pump to withdraw an evaluating agent from a reservoir. The branched or multi-way valve can moreover be provided with a plurality of necks connected to other eluent reservoir, respectively.
It is to be understood that the supplying period of an organic solvent admixture is not limited to the duration of the chromatographic process, but it can preferably precede the start of the latter; thus the admixture can be supplied before the specimen substance to be chromatographically separated has been carried into the column.
The effect of the enriched buffer solution before the moment or instant of carrying-in of the specimen sub stance is given in that there is provided a sufficient time period allowing the grains of the chromatographic charge to get saturated by diffusion before the specimen substance has been carried in. Thus the chromatographic reaction proceeds from the very beginning on said grains saturated up to a sufficient depth with the enriching alcohol admixture by which the relative chromatographic positions of the particular components are determined. In this way it is possible to attain maximum effects of said admixture upon the components having high migration speeds, and simultaneously to limit the same effect which could later undesirable affect the separation of the com- 3 ponents having lower migration speeds, as hereinbefore explained, after all.
In cases of chromatographic separating reactions proceeding at very high rates it is possible to attain the maximum effect even if the alcohol admixture supply take place exclusively before the specimen substance has been carried in, and if the supply of the buffer free of said admixture is started in the very instant of carrying-in of the specimen substance to be chromatographically separated, or just before this instant. It results from the foregoing that the main idea of the present invention consists in that a sufficiently intensive and shortly enduring pulse of the admixture concentration is established, which pulse is capable to provoke an intensive shorttimed wave of the admixture concentration in the ion exchanger grains. The form, size and position of the concentration wave in the entire course of the chromatographic process have such a character causing positive effects on the separation of some selected amino acid pairs, an undesirable effect of said concentration wave being simultaneously reduced to a minimum acceptable in respect of the positive effect thereof on the abovementioned amino acid pair.
The necessary rapid changes in buffer quality, or the replacement of the buffers, can be, for example, cared for by a multi-Way valve, programed pump, or the like.
A preferable practice of carrying out the method according to the invention consists in that the chromatographic process including the prestabilization of the column by the respective buffer solution as well as the carrying-in of the specimen substance on to the column takes place at a continuous buffer flow. To meet this requirement it is recommended to use such a column seal excluding a free space above the column charge.
In practice the method according to the resent invention can for example, be carried out in that a mixture of amino acids is chromatographically separated on a pair of columns of which one is designed for the separation of both acidic and neutral amino acids while the second, a smaller one, serves for the separation of basic amino acids; the elution on the bigger column is performed in that the column is stabilized with a citrate buffer solution containing percent admixture of an organic solvent, about eight minutes before the column has been fed with the specimen substance; after carrying-in the specimen substance the elution with said enriched buffer proceeds for about 13 minutes whereupon it takes place without said organic solvent admixture. After a period of 120 minutes has elapsed, i.e., when almost perfect separation of all particular components from one another has occurred, the complete analysis on both columns is carried out. It can be found out that the relative distance between threonine and serine on the resulting chromatogram, which distance usually is critically small, is now approximately as great as the distance between aspartic acid and threonine, the separation of the amino acids remaining almost perfect.
The novel features which are considered as characteristic for the invention are set forth in particular in the appended claims. The invention itself, however, both as to its construction and its method of operation, together with additional objects and advantages thereof, will be best understood from the following description of specific embodiments when read in connection with the accompanying drawings.
BRIEF DESCRIPTION OF THE DRAWING FIG. 1 shows a chromatogram involving an interval from the elution of the .amino acid of valine up to the elution of the amino acid of phenylalanine; and
FIG. 2 is a schematic view showing a specific embodiment of an apparatus for carying out the method according to the invention.
4 DESCRIPTION OF THE PREFERRED EMBODIMENT The chromatogram in FIG. 1 is a graphical representation of a chromatographic reaction starting with the elution of the amino acid of valine, which designated by the curve peak A. Until the elution of valine is finished, a citrate buffer is supplied having pH-value of 4.25 and normality of 0.2. The chromatographic reaction then proceeds by means of a buffer of pH 5.28 and normality of 0.38, the outlet of the frontal part of the last mentioned buffer occurring between the outlets of amino acids of leucine and tyrosine (See peaks D and E, respectively), whereupon the chromatographic column is regenerated by washing with sodium hydroxide. Peak B designates the elution of methionine amino acid, peak C isoleucine amino acid and peak F phenylalanine amino acid. As results from the positions of peaks E and F, the relative separation of the amino acid pair of tyrosine-phenylalanine, which pair usually is a critical one as to the separation, is not only substantially accelerated, but also improved.
The apparatus for carrying out the method according to the invention comprises, as shown in FIG. 2, a chromatographic column 1 the upper seal 2 of which is connected to the outlet portion of a pump 3 by means of a pipe 4. The inlet portion of the pump 3 communicates via another pipe 5 with a branched or multi-Way valve 6 establishing the connection of the pipe 5 with one of circumferentially arranged necks 7, 10, 21, 22 and 29. The neck 7 is connected to an eluent reservoir 9 by the intermediary of a pipe 8. Another neck 10 is connected in turn to the one neck 30 of a vessel 11 containing the specimen substance. The other necks 21, 22 and 29 communicate via pipes 23, 24 and 25, respectively, with other eluent reservoirs 26, 27 and 28. The second neck 31 of the vessel 11 is connected via a branched pipe with pipes 12 and 32. The pipe 12 connects the vessel 11 for the specimen substance with the pipe 8 extending from the eluent reservoir 9 to the neck 7 of the branched valve 6. On the other hand, the pipe 32 communicates with a pipe 13 extending from an other eluent reservoir 14. The lowermost part of the chromatographic column 1 is connected via a pipe 15 passing a capillary reactor 16 to an evaluating instrument 17, preferably a photometer. By means of a pipe 21 the pipe 15 communicates with a pump 20 withdrawing the evaluating agent from a reservoir 18 thereof through a pipe 19.
In operation the branched or multi-way valve 6 which can be controlled manually, or automatically from a not shown program control means, establishes the connection of any one of the eluent reservoirs, 9, 14, 26, 27 and 29 with the chromatographic column 1 whereby an eluent necessary for carrying out the method of elution column chromatography of amino acid mixtures according to the invention may be selected. By the intermediary of said branched valve 6 the vessel 11 for the specimen substance is simultaneously connected to the chromatographic column 1.
The described branched valve 6 can preferably be replaced by a pump supplying the eluents into the chromatographic column according to a predetermined program control.
In order to obtain a continuous flow of the eluents and of the specimen substance into the chromatographic column 1 a free space adjacent the upper seal 2 thereof has to be avoided.
When separating the eluate flow in the capillary reactor into individual sections by means of bubble pistons it is possible to attain, e.g., in an analytical process within a period of 45 minutes, a practically complete separation of the amino acid pair of threonine-serine as well as other amino acid pairs from each other if musing the method according to the invention in that a buffer solution enriched with 6 percent of an organic solvent is supplied to stabilize the columns for a period of 2 /2 hours before carrying-in the specimen substance, and for a period of 8 minutes after the specimen substance has been carried in.
While the invention has been illustrated and described as embodied in a method and apparatus for chromatographically separating amino acid mixtures, it is not intended to be limited to the details shown, since various modifications and structural changes may be made without departing in any way from the spirit of the present invention.
Without further analysis, the foregoing will so fully reveal the gist of the present invention that others can by applying current knowledge readily adapt it for various applications without omitting features that from the standpoint of prior art clearly constitute essential characteristics of the generic and specific aspects of this invention and therefore, such adaptations should and are intended to be comprehended within the meaning and range of equivalence of the following claims.
What is claimed as new and desired to be protected by Letters Patent is:
1. A method for the chromatographic separation of amino acid mixtures by means of column chromatography, which method comprises the steps of:
(a) introducing onto the column an amino acid mixture including leucine, tyrosine and phenylalanine,
(b) eluting the amino acid mixture with a first buffer until the elution of leucine, and
(c) eluting the amino acid with a second buffer at least until elution of tyrosine and phenylalanine, the pH-value and normality of the second bufier increased by leaps relative to the respective values of the first buffer.
2. The method of claim 1 wherein the increase by leaps is effected by rapidly changing the feed of buffer to the column from the first butter to the second bufiter having the increased pH-value and normality.
3. A method for the chromatographic separation of amino acid mixtures by means of column chromatography, which method comprises the steps of:
(a) introducing onto the column an amino acid mixture including valine, leucine, tyrosine and phenylalanine,
(b) eluting the amino acid mixture with a first citrate butter until the elution of valine,
(c) introducing onto the column a second buffer, the second buffer having an increased pH-value and normality relative to the respective values of the first butter and the column being rapidly changed to the second bufler is established in the column,
(d) eluting the amino acid mixture until at least the elution of phenylalanine whereby the outlet from the column of the frontal part of the second buffer occurs between the outlets from the column of leucine and tyrosine,
(e) evaluating the chromatographically separated amino acids, and
(f) regenerating the column.
References Cited UNITED STATES PATENTS 3,334,969 8/1967 Catravas 23253X 3,373,872 3/1968 Hrdina 23-253UX 3,446,598 5/1969 Yoder et al 23-230 3,458,285 7/1969 Hrdina 23-230 3,463,615 8/1969 Sochor 23-253X OTHER REFERENCES Schroder, et al.: Chromatographic Separation of Peptides on Ion Exchange Resins, Analytical Chemistry, vol. 34, No. 12, November 1962, pages 15701575.
MORRIS O. WOLK, Primary Examiner R. E. SERWIN, Assistant Examiner US. Cl. X.R.
mg UNITED STATES PATENT OFFICE CERTIFICATE OF CORRECTION December 29, 1970 Patent No. 3, 107 Dated Inventor-(s) JIRI HRDINA It is certified that error appears in the above-identified patent and that said Letters Patent are hereby corrected as shown below:
IN THE CLAIMS In claim 1, line 9, after "until" and before "elution" insert the In claim 3, line 13, after "second buffer" and before "is established", insert whereby a concentration wave of the second buffer Signed and sealed this 23rd day of March 1971.
(SEAL) Attest:
Commissioner of Patents Attesting Officer
|Citing Patent
|Filing date
|Publication date
|Aug 6, 1973
|Oct 28, 1975
|Dow Chemical Co
|Quantitative analysis of single ion species
|Jun 25, 1975
|Jan 20, 1976
|Durrum Instrument Corporation
|Constant flow system for detection of amino acids
|Oct 24, 1985
|Dec 16, 1986
|Etd Technology, Inc.
|Analysis of organic compounds in baths used in the manufacture of printed circuit board using novel chromatographic methods
|Oct 29, 1986
|Apr 26, 1988
|Merck & Co., Inc.
|Process for purified amino acids
|May 17, 1984
|Oct 30, 1985
|Analysis of organic additives in plating paths using novel chromatographic methods in a mass balance approach
|U.S. Classification
|436/89, 530/344, 210/316, 422/70, 210/656
|International Classification
|Cooperative Classification
|European Classification


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SVU Set Visit
No, it wasn't an April Fools' joke. On Friday, April 1, 2016, I was able to visit the set of Law & Order: SVU No, it wasn't an April Fools'… Read more »
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My spreadsheet has gone berserk. Not only do I have columns for my monthly goal as well as to top the month the prior year, I have columns for 1m… Read more »
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You can take the girl out of Japan, but you can't take the Japan out of the girl. Specifically, the love of cherry blossoms ingrained in me in April 2002… Read more »


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- Fri, Aug 19, 2016
On #WorldHumanitarianDay, Mercy Ships® celebrates students in Africa who can return to school because they received surgeries to remove tumors, straighten crooked feet, repair cleft lips or correct other maladies that once made them outcasts.
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Gopher Traps
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With 512 full color pages and 1120 full color photographs and illustrations, Marijuana Horticulture: The Indoor/Outdoor Medical Grower's Bible is the most complete cultivation book available. The Fifth Edition of the former Indoor Marijuana Horticulture: The Indoor Bible was originally published in 1983, when it immediately became a best seller...
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I-88 Speedway
[CRSA Sprint Car Website] [IMCA Modified Website] [SRP Sprints Website] [I-88 Speedway Classes] [2016 Racing Season News Release]
I-88 Speedway Racing Status and News!
Track Status and news!
I-88 Speedway is now on Twitter! @i88_Speedway
Friday, October 7 & Friday, October 8 Racing - Short Track SuperNationals
Short Track SuperNationals 9 takes place Friday-Saturday October 7-8 at the pristine I-88 Speedway three-tenths-mile oval. The weekend serves as the championship round of the Bob Hilbert Sportswear Short Track Super Series (STSS) Fueled By VP Halmar International North Region amidst two full days of racing action.
Friday Night
The Friday (Oct. 7) program will be headlined by STSS Open Sportsman paying $1,500 to win (*with Gambler's Fee) for 35 laps plus XCel 600 Modifieds, Street Stocks, Empire Lightning Sprints and Modified open practice rounds.
Friday admission prices are as follows: $15 for Adults, $13 for Seniors (ages 65 and up), $10 for Students (ages 9-14) with children eight and under FREE. Pit admission is $30, with no license required.
Pit gates open at 3 p.m. on Friday. Grandstand gates are unlocked at 4 p.m. Hot laps begin at 6 p.m., with racing at 7 p.m.
Saturday Night
Saturday (Oct. 8) will again be a "split" program with racing in the afternoon and evening. Divisions to be featured on Saturday are STSS Modifieds in a 50-lap, $5,000-to-win main, GRIT Series Crate 602 Sportsman, XCel 600 Modifieds, Empire Lightning Sprints, Empire Sport Trucks and Vintage Cars.
Saturday admission prices are $22 for Adults, $20 for Seniors (ages 65 and up), $12 for Students (ages 9-14) and children eight and under are FREE. Pit admission is $35, with no license required.
Pit gates open at noon on Saturday. Grandstand gates are unlocked at 1 p.m. Hot laps begin for GRIT Sportsman, XCel 600 Modifieds, Lightning Sprints, Sport Trucks and Vintage Cars at 3 p.m., with heat races to follow immediately.
STSS Modified hot laps are scheduled for 6 p.m. with heat races to follow.
For additional information, including links to entry forms and camping forms, read the complete Short Track Super Series News Release.
September 23 & 24 Racing Canceled
The Fall 250 racing program at I-88 Speedway scheduled for September 23 and 24 has been canceled. Promoters Jamie and Denise Page have made the difficult decision after considering the number of competing events at other speedways in the state and the financial risk involved in the program. Declining car counts and attendance for this event over the past two seasons also contributed to this decision. Also the inclement weather forecast for Sunday's Wade Decker Memorial at Thunder Mountain Speedway may necessitate the need for a rain date. The cancellation of the Fall 250 allows those dates to be available should they be needed for this prestigious event.
The final event of the 2016 racing season will take place on October 7 and 8 with the ninth running of the Short Track SuperNationals.
Friday, September 9, 2016 Racing ~ Greg Page Construction Night ~ Results
Greg Page Construction Modified Winner Andy Bachetti
Chambers and O'Hara Sportsman Winner Claude Hutchins Jr.
NuLook Collision Street Stock Winner Doug Polhamus
Xcel Modified Winner A.J. Miller
Butler Auto Sales 4 Cylinder Trucks Winner Bob Crandall
Images © SJS Photo
Click on image for larger version. Andy Bachetti put a bow on a dominant season at I-88 Speedway on Greg Page Construction and River Road Auto Night but not only winning the feature but capturing the Modified track championship and the Summer Slam championship.
Bachetti, of Sheffield MA, make the Afton oval his Friday night home in 2015 finishing third in the point standings and garnering two feature wins. His second season at the track started with a second place finish followed by two wins which set the stage for the show that was to follow over the remaining months of the season.
Winning 9 of 17 races during the year, Bachetti had the championship well in hand when second place Mike Mahaney, of King Ferry, was unable to compete on championship night due to other racing commitments.
On championship night Bachetti would take the lead from Norwich's Alan Barker on lap 26 and cruise to the win.
J.R. Hurlburt, of Otego, took the lead at the start of the Modified feature but would surrender the lead to Barker on lap two. Barker would open a full straightaway lead until the caution came out on lap 8 putting Hurlburt second, Cortland's Nick Nye third, Mike Clapperton, of Masonville, fourth and Norwich's Mitch Gibbs fifth. At the drop of the green Bachetti moved into the top five.
Read the entire race recap.
FINAL Points as of 09/09/16 have been posted:
[Modified Points] [Sportsman Points] [Crate Sportsman Points] [IMCA Points] [Street Stock Points] [Excel Modified Points] [4 Cyl Truck Points]
Greg Page Construction Modifieds Fall Championship (35 Laps):
Andy Bachetti, Nick Nye, Darwin Greene, Mike Clapperton, Ken Titus, Rusty Smith, Brian Malcolm, Brett Tonkin, Kurt Decker, Chris Bushnell, Kenny Sparks, Mitch Gibbs, Alan Barker, Nick Rochinski, J.R. Hurlburt, Duane Hiller, Steve Babicek, Paul Jensen, Mike Trautschold (placed last after weighing light)
Greg Page Construction Modified Track Champion:
Andy Bachetti
Chambers and O'Hara Sportsmen Fall Championship (25 Laps):
Claude Hutchings Jr., Aaron Shelton, Charlie Hendrickson Jr., Butch Klinger, Dave Rosa, Bill Deckelman, Craig Pope, Jeremy Vunk, Jim Gould, Lisa Williams, Denny Greenier, Steve Andersen DNS Dwayne Jackson
Chambers and O'Hara Sportsmen Track Champion:
Charlie Hendrickson Jr.
Williams Tire And Auto Crate Sportsmen Fall Championship (25 Laps):
Cody Clark, Harold Humphrey, A.J. Miller, A.J. Digsby, Brandon Kuhn, Matt Roberts, Willy Decker Jr., Matt Priscot, Josh Mudge, Duane Knapp, Allan Hodge, Bobby Heintz, Olin Renwick, Jimmy Zacharias, Todd Titus, Matt Brewer, Tim French II, Art Priscott
Williams Tire and Auto Crate Sportsmen Track Champion:
Harold Humphrey
Nu Look Collison Street Stock Fall Championship (25 Laps):
Doug Polhamus, Dave Cronk, Matt Bowman, Dustin Harris, Tommy Groover, Ernie Staelens, Damon Decker, Matt Spencer, Steve Polhamus, Ralph Cuozzo DNS Matt Thies
Nu Look Collision Street Stock Track Champion:
Dustin Harris
MR Graphix Xcel Modifieds (Make up from August 19, 15 Laps):
A. J. Miller, Eric Boyd, Bailey Boyd, Steven Sherwood, Kamdin Maby, Dana Davis, Will Eastman, Bob Rowback, John Burnside, Paul DeRuyter DNS C.J. Jochum
MR Graphix Xcel Modified Track Champion:
Will Eastman
MR Graphix Xcel Modifieds (20 Laps):
A.J. Miller, Eric Boyd, Kamdin Maby, Bailey Boyd, Paul DeRuyter, Will Eastman, Bob Rowback, Steven Sherwood, Dana Davis, John Burnside
Butler Auto Sales EST Trucks (20 Laps):
Bob Crandall, Jerry Lanfair, Ralph Cuozzo, Rob Loucks, Dustin Wilber, Steve Judd, James Fowlston, Brandon Clapperton
2016 Butler Auto Sales EST Truck Track Champion:
Rob Loucks
Friday, September 2, 2016 Racing ~ Williams Tire & Auto Night ~ Results
Greg Page Construction Modified Winner Mike Mahaney (08/12 feature make-up)
Greg Page Construction Modified Winner Paul Jensen
Chambers and O'Hara Sportsman Winner Claude Hutchins Jr. (08/12 feature make-up) (image from 06/24)
Chambers and O'Hara Sportsman Winner Craig Pope
Williams Tire and Auto Crate Sportsman Winner Matt Brewer (08/12 feature make-up)
Williams Tire and Auto Crate Sportsman Winner Matt Roberts
Vernooy's Automotive Excellence IMCA Modified Winner Matt Cole
NuLook Collision Street Stock Winner Dustin Harris
Butler Auto Sales 4 Cylinder Trucks Winner Rob Loucks
Xcel Modified Winner Will Eastman (Image from 07/15)
Images © SJS Photo
Click on image for larger version.It was a busy night at I-88 Speedway with double features for three of the open wheel divisions with Mike Mahaney taking the opening Modified feature and Paul Jensen followed up with the win in the nightcap. In the Open Sportsmen division Claude Hutchings Jr. returned to victory lane after taking the early race win before Craig Pope took home his first I-88 Speedway feature winner's trophy in the regularly scheduled event. In the Crate Sportsmen class Matt Brewer won his second consecutive feature in the opener while Matt Roberts won the final open wheel race of the night.
Mike Mahaney, of King Ferry, grabbed his second Greg Page Construction Modified feature win of the season in the held over race from August 12. Mahaney started 12th in the field before taking the lead from Binghamton's Steve Babicek on lap 24.
Chris Bushnell, of Cortland, took the lead at the start of the Modified feature before the caution came out on lap one after Andy Bachetti spun in turn three and collected Duane Hiller.
The race restarted with Bushnell leading, Ken Titus, of Binghamton running second, Babicek third, Darwin Greene, of Susquehanna PA, fourth and Afton's Kurt Decker fifth.
On the restart Babicek pressured Titus for second using the inside line around the speedway before taking over the spot.
By lap eight Bushnell led Babicek by two lengths with Titus holding off Decker for third and Greene in fourth.
Babicek slipped under Bushnell on lap ten and took the lead coming off turn four.
At the halfway point Babicek opened a half straight away lead over Bushnell with Decker third, Alex Tonkin, of Carbondale PA, fourth and Mahaney fifth.
With ten laps remaining Mahaney began to challenge Decker for third and made the pass coming off turn two before the caution came out as Greene slowed in turn four.
Read the entire race recap.
Greg Page Construction Modifieds (Postponed from August 12, 30 Laps):
Mike Mahaney, Steve Babicek, Chris Bushnell, Brett Tonkin, Paul Jensen, Kurt Decker, Rusty Smith, Andy Bachetti, Ken Titus, Alan Barker, Mike Clapperton, Mitch Gibbs, Brandon Walters, J.R. Hurlburt, Nick Nye, Mike Trautschold, Darwin Greene, Kenny Sparks, Duane Hiller, Jeff Sheely DNS Alex Tonkin
Greg Page Construction Modifieds (30 Laps):
Paul Jensen, Andy Bachetti, Rusty Smith, Mike Clapperton, Alan Barker, Nick Nye, Chris Bushnell, Steve Babicek, Brett Tonkin, Brandon Walters, Kurt Decker, Mitch Gibbs, Ken Titus, Mike Mahaney, J.R. Hurlburt, Mike Trautschold, Darwin Greene, Kenny Sparks, Duane Hiller, Jeff Sheely
Chambers and O'Hara Open Sportsmen (Postponed from August 12, 30 Laps):
Claude Hutchings Jr., Dave Rosa, Charlie Hendrickson Jr., Jim Gould, Aaron Shelton, Butch Klinger, Jeremy Vunk, Steve Andersen, Bill Deckelman, Craig Pope, Denny Greenier, Landon Cummings, Lisa Williams, Skip Pickwick, Tom Tophoven, Dwayne Jackson, Landon Cummings
Chambers and O'Hara Open Sportsmen (20 Laps):
Craig Pope, Claude Hutchings Jr., Lisa Williams, Dave Rosa, Jeremy Vunk, Charlie Hendrickson Jr., Denny Greenier, Steve Andersen, Aaron Shelton, Butch Klinger, Jim Gould, Bill Deckelman, Dwayne Jackson, DNS Tom Tophoven, Skip Pickwick, Eric Williams
Williams Tire and Auto Crate Sportsmen (Postponed from August 12, 30 Laps):
Matt Brewer, Cody Clark, A.J. Miller, Harold Humphrey, Matt Roberts, Brandon Kuhn, Aaron Jacobs, Olin Renwick, Matt Priscott, Allan Hodge, A.J. Digsby, Duane Knapp, Fred Christ, Art Priscott, Pat Jordan placed last after weighing light.
Williams Tire and Auto Crate Sportsmen (20 Laps):
Matt Roberts, Harold Humphrey, Brandon Kuhn, Olin Renwick, Cody Clark, A.J. Miller, Aaron Jacobs, Allan Hodge, Matt Brewer, Matt Priscott, A.J. Digsby, Jake Gradacker, Pat Jordan, Duane Knapp, Fred Christ, Art Priscott, Eric Williams
Vernooy's Automotive Excellence IMCA Modifieds Season Championship (25 Laps):
Matt Cole, Beau Ballard, James Cornell, Will Ward, Gary Roberts, Bill Nichols, Aaron Jacobs, Gary Smith, Tim Vandemark DNS Tyler Stoddard
Nu Look Collision Street Stocks (20 Laps):
Dustin Harris, Dave Cronk, Doug Polhamus, Jake Fowlston, Damon Decker, Matt Thies, Ralph Cuozzo, DNS Steve Polhamus
Butler Auto Sales EST Trucks (15 Laps):
Rob Loucks, Bob Crandall, Ralph Cuozzo, Dustin Wilber, Steve Judd, James Fowlston, Trey Palmer, Jerry Lanfair and Brandon Clapperton placed last after weighing light
MR Graphix Xcel Modifieds Midseason Championship (20 Laps):
Will Eastman, A.J. Miller, Kamdin Maby, Steven Sherwood, Eric Boyd, Bailey Boyd, Paul DeRuyter, John Burnside, Bob Rowback
Friday, August 26, 2016 Racing ~ Neighbors Insurance Night ~ Results
Greg Page Construction Modified Winner Andy Bachetti
Chambers and O'Hara Sportsman Winner Charlie Hendrickson Jr.
Williams Tire and Auto Crate Sportsman Winner Matt Brewer
Vernooy's Automotive Excellence IMCA Modified Winner Beau Ballard (08/12 feature make-up)
Vernooy's Automotive Excellence IMCA Modified Winner Matt Cole
NuLook Collision Street Stock Winner Damon Decker (8/12 feature make-up AND 08/26 feature)
Butler Auto Sales 4 Cylinder Trucks Winner Rob Loucks (08/12 feature make-up)
Butler Auto Sales 4 Cylinder Trucks Winner Ralph Cuozzo (08/12 feature make-up)
FWD 4 Cylinder Cars Winner Mike Robinson
FWD 4 Cylinder Cars Winner Rich Gardiner
Xcel Modified Winner Will Eastman
Images © SJS Photo
Click on image for larger version.Andy Bachetti took home his eighth Greg Page Construction Modified Feature Winner's trophy on Neighbors Insurance Night at I-88 Speedway. Bachetti, of Sheffield MA, started 12th in the 20 car field and worked his way to the front taking the lead when Afton's Kurt Decker's engine expired while leading on lap 15.
"Just glad this car's back to the way it was. It was a pretty hard hit, we put a clip on the nose of it and we weren't sure if it was going to be as good as it was. Right now it's pretty good," said Bachetti in victory lane.
Kurt Decker and Chris Bushnell, of Cortland ran side by side at the start of the race with Decker leading lap one by a wheel with Binghamton's Ken Titus third.
Lap three it was Decker by one car length over Titus while Bachetti was working the outside running in sixth place.
By lap five Decker had opened a three car length lead over Bushnell with Titus running third, Tonkin fourth and Bachetti up to fifth.
Decker pulls out to a half straightaway lead over Bushnell as Bachetti switches to the bottom and moves into fourth place.
On the tenth lap Bachetti worked under Titus to take over third as Decker opens over a half straightaway lead over Bushnell with Bachetti on Bushnell's back bumper in third. Four laps later Bachetti passed Bushnell coming off turn four to take over second.
On lap fifteen the caution came out as Decker breaks while leading putting Bachetti in the lead.
At the halfway point for the restart, Bachetti led with Bushnell second, Titus third, King Ferry's Mike Mahaney fourth and Tonkin fifth.
When the race went back to green Bachetti pulled away from the field as Bushnell, Titus and Mahaney battled for second through fourth.
Read the entire race recap.
Greg Page Construction Modifieds (30 Laps):
Andy Bachetti, Ken Titus, Mike Mahaney, Rusty Smith, Mitch Gibbs, Mike Clapperton, Chris Bushnell, Brett Tonkin, Nick Nye, Jeff Sheely, Darwin Greene, Mike Decker, J.R. Hurlburt, Brandon Walters, Kenny Sparks, Steve Babicek, Paul Jensen, Alan Barker, Kurt Decker, Duane Hiller
Chambers and O'Hara Open Sportsmen (20 Laps):
Charlie Hendrickson Jr., Jim Gould, Aaron Shelton, Butch Klinger, Dwayne Jackson, Steve Andersen, Craig Pope, Lisa Williams, Tom Tophoven, Denny Greenier, Duane Knapp, Claude Hutchings DNS Skip Pickwick
Williams Tire and Auto Crate Sportsmen (20 Laps):
Matt Brewer, Harold Humphrey, Cody Clark, Matt Roberts, A.J. Digsby, A.J. Miller, Brandon Kuhn, Allan Hodge, Olin Renwick, Jamie Batzel, Willy Decker Jr., Aaron Jacobs, Tom Princiotta, Art Priscott, Mike Decker, Matt Priscott
Vernooy's Automotive Excellence IMCA Modifieds make up from August 12 (20 Laps):
Beau Ballard, James Cornell, Matt Cole, Tyler Stoddard, Will Ward, Gary Roberts, Mike Stoddard, Gary Smith, Aaron Jacobs, Jesse Velez, Jim Cummings, Chris Shultis, Tim Vandemark DNS Logan Terry
Vernooy's Automotive Excellence IMCA Modifieds (20 Laps):
Matt Cole, Will Ward, James Cornell, Beau Ballard, Tyler Stoddard, Mike Stoddard, Aaron Jacobs, Jim Cummings, Gary Roberts, Chris Shultis, Gary Smith, Jesse Velez, Eric Stumpf, Bobby Collins DNS Tim Vandemark
Nu Look Collision Street Stocks make up from August 12 (20 Laps):
Damon Decker, Dustin Harris, Doug Polhamus, Matt Bowman, Tommy Groover, Dave Cronk, Steve Polhamus, Jake Fowlston, Rich Fife, Matt Thies, Jason Neyra, Shane Wolf, Ralph Cuozzo
Nu Look Collision Street Stocks (20 Laps):
Damon Decker, Doug Polhamus, Dave Cronk, Tommy Groover, Rich Fife, Jake Fowlston, Jason Neyra, Ralph Cuozzo, Matt Thies, Steve Polhamus, Matt Bowman, Dustin Harris DNS Shane Wolf Jr.
Butler Auto Sales EST Trucks Make up from August 12 (15 Laps):
Rob Loucks, Brandon Clapperton, Bob Crandall, Ralph Cuozzo, Steve Judd, Jim Fowlston, Dylan Decker, Bray Kawalski, Dustin Wilber, Jerry Lanfair, DNS Pete Van Noordt
Butler Auto Sales EST Trucks (15 Laps):
Ralph Cuozzo, Bob Crandall, Rob Loucks, Steve Judd, Jerry Lanfair, James Fowlston, Dustin Wilber, Bill Cooper, Brandon Clapperton, Rob Northrup, DNS Bray Kawalski
FWD 4 Cylinders Make up from August 12 (15 Laps):
Mike Robinson, Rich Gardiner, Nick Kennedy, Frankie Kennedy, Chris Andrew, Tim Vandemark, Phil Burns, Chris Nichols, Josh Amatuccio, Rich Wagner, Sheldon Whitman, Jeremy Warren, Bryan Brown DNS Chris Taylor, Jason Colwell, Adam Gilbert, Josh Wilder, Andy Brigham
FWD 4 Cylinders (15 Laps):
Rich Gardiner, Tim Vandemark, Chris Andrew, Phil Burns, Chris Nichols, Nick Kennedy, Mike Robinson, Frankie Kennedy, Jeremy Warren, Bryan Brown, Rich Wagner
American Racer/ VP Fuels Xcel Modified (20 Laps):
Will Eastman, A.J. Miller, Aaron Bowes, Michael Burrows, Jon Josko, Kyle Fallis, Dylan McCrone, Kamdin Maby, D.J. Hunt, Richie Hitzler, Brian Blankenbiller, Scott Heilman, Travis Fichter, Hunder Deihl, Grant Schibilia, John Burnside, Bailey Boyd, Paul Rooney
I-88 Speedway Classes
- Greg Page Construction Modifieds
- Chambers and O'hara Open Sportsman
- Williams Tire and Auto Crate Sportsman
- MR Grafix Xcel 600 Modifieds
- NuLook Collision Street Stocks
- VerNooy's Automotive Excellence IMCA Modified
- Butler Auto Sales 4 Cylinder Trucks


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Shiny new overalls for our workshop boys
Smiles almost all round in Churchstoke workshop!
Massey stage a convoy in Coventry
Massey Ferguson staged a convoy of 70 tractors old and new to mark 70 years since the classic TE-20 was produced.
Say hello to the new face on the Pughs team
Theres a new face on the RVW Pugh team, come in and say hello!
The weather comes out for staff BBQ
The staff from all three depots got together for a Summer BBQ.
Cruckton and Cheshire Ploughing Matches
Royal Cheshire Show
Come and visit our stand at this years show. It will be bigger and better than ever!
2016 Arable Event
The Arable Event 2016 - not to be missed!
Soil & Grass Preparation Demo Day


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Cedric the Entertainer stars in this spinoff of popular TV Land sitcom "Hot in Cleveland," as Boyce "The Voice" Ballentine, a former R&B superstar who has become a minister. When he gets the calling to go from soul singer to soul saver, he moves from Las Vegas to St. Louis with his wife and daughter to take over preaching duties at his father's church. His family members aren't thrilled with the lifestyle change and they have to adjust from the superstar life they had in Sin City to a humble new life in the Midwest. Beginning with the show's second season, episodes end with a two-minute stand-up comedy routine by Cedric, which relates to the episode's topic.
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