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The ARTS of third-generation mineralocorticoid receptor antagonists: achieving cardiovascular benefit with minimized renal side effects?
This editorial refers to 'Safety and tolerability of the novel non-steroidal mineralocorticoid receptor antagonist BAY 94-8862 in patients with chronic heart failure and mild or moderate chronic kidney disease: a randomized, double-blind trial,'† by B. Pitt et al., on page 2453
The mineralocorticoid receptor antagonists (MRAs) spironolactone and eplerenone have been proven to reduce total mortality and hospitalization in three large randomized controlled trials in patients with symptomatic chronic heart failure and patients with left ventricular dysfunction and heart failure symptoms early after myocardial infarction. This marked and sustained evidence-proven benefit led to the class I recommendation for MRAs in the treatment of all patients with symptomatic systolic heart failure already treated with angiotensin-converting enzyme (ACE) inhibitors and beta-blockers.1−3
Despite considerable efforts to enable the broad application of these life-saving medications in all patients with systolic heart failure,4 many clinicians are still reluctant to employ MRAs in their clinical practice.5 While these restraints are hard to understand in heart failure patients with normal kidney function, worsening renal function and hyperkalaemia are significant clinical problems in patients with mild to moderate, and especially with severe, renal dysfunction. However, when contraindications such as co-medication with potassium-sparing diuretics are respected and renal function and potassium levels are closely followed, patients with mild to moderate renal insufficiency appear to gain similar reductions in mortality and hospitalization by MRA treatment as heart failure patients with normal renal function.6 Although patients with severe renal dysfunction had been excluded from the mortality studies investigating MRAs in heart failure, there is growing interest not only from heart failure specialists, but also from nephrologists to treat these patients too with low dose MRAs to obtain cardiovascular but also potential renal benefits.
How will it be possible for broad patient populations including the elderly and those with chronic kidney disease to profit from the clear-cut cardiovascular benefits of MRAs without suffering from risks such as worsening renal function and hyperkalaemia? Can we separate the renal and cardiovascular actions of MRAs?
Experimental evidence suggests that depending on their cell-specific activation, mineralocorticoid receptors (MRs) precipitate a plethora of different adverse cardiac and vascular effects.7 In addition to the MRs in epithelial cells of the distal colon and renal nephron whose activation mediates the classical actions of aldosterone, i.e. sodium reabsorption and potassium excretion, MRs have been identified in vascular endothelial and smooth muscle cells as well as in cardiomyocytes, endothelial cells, fibroblasts, and macrophages in the heart.7,8 Recently, investigations in mice with cell-specific overexpression or deletion of the MR in cardiomyocytes or vascular smooth muscle cells provided evidence that activation of the cardiovascular MR is a main driver for the development and progression of hypertension and heart failure.7,9,10 Thus, treatment of cardiovascular disease with MRAs may prove to be feasible using novel MR blockers with enhanced tissue selectivity compared with spironolactone and eplerenone. The advantage of eplerenone as a so-called 'second-generation MRA' compared with spironolactone is mainly the higher selectivity for MRs to avoid hormonal side effects such as gynaecomastia; however, eplerenone displays only low MR blocking potency (Figure 1). Several pharmaceutical companies have developed novel MR-antagonizing compounds.11,12 These so-called 'third-generation MRAs' are non-steroidal compounds with both high selectivity and high potency to inhibit the MR. The first compound of these novel MRAs undergoing clinical evaluation, BAY 94-8862, appears, furthermore, to display a distinct tissue distribution different from that of first- and second-generation MRAs: while spironolactone and—to a somewhat lesser extent—eplerenone are enriched in the kidneys as compared with the heart, BAY 94-8862 appears to have an equal tissue distribution. Will BAY 94-8862 fulfil the hope of achieving cardiovascular benefit without or at least with fewer renal side effects than spironolactone and eplerenone?
The first phase II clinical trial with this promising compound has now been published.13 The minerAlocorticoid-Receptor Antagonist Tolerability Study (ARTS) is a 4-week randomized, double-blind trial investigating increasing dosages of the novel non-steroidal MRA BAY 94-8862 compared with placebo or open-label spironolactone in patients with systolic heart failure [New York Heart Association (NYHA) class II/III] and mild to moderate chronic kidney disease. In the main part B of the study, the novel MRA was given at several dosages to heart failure patients with moderate renal insufficiency [estimated glomerular filtration rate (eGFR) 30–60 mL/min/1.73 m2]. The main results are very encouraging, as BAY 94-8662 was associated with significantly less hyperkalaemia, worsening renal function, and blood pressure decrease in comparison with spironolactone (25–50 mg). Although the average age of the patients in the main study was 72 years, it is of special importance that in a subanalysis of patients aged >75 years the advantage of BAY 94-8862 regarding increases in potassium concentration and eGFR decrease over the spironolactone group was maintained.
Clearly, it remains to be proven that the novel compound is at least as effective as spironolactone in the prevention of major cardiovascular events. Although this question could not be addressed in the 4-week ARTS study, several surrogate parameters point to a maintained effect of BAY 94-8862 in this regard: the biomarkers brain natriuretic peptide (BNP) and N-terminal pro brain natriuretic peptide (NT-proBNP), as well as albuminuria were reduced by the novel MRA at least as much as with spironolactone, thus providing reassurance that the lower incidence of side effects most probably does not come at the expense of lower efficacy.
Given the class I recommendation for an MRA in all patients with symptomatic systolic heart failure, the results of the ARTS trial are of utmost importance as the risk of hyperkalaemia and worsening renal function is the main obstacle of an even broader utilization of MRAs in clinical practice. Further assessment of BAY 94-8862 is mandatory. An important question in this regard is the adequate comparator. As eplerenone was very successful in the EMPHASIS trial,14 and, despite the lack of direct comparative data, the assumption that it may be associated with less severe hyperkalaemia than spironolactone,4 it appears to be a wise choice to compare BAY 94-8862 with eplerenone in the 90-day phase IIb ARTS-HF study in patients hospitalized with worsening chronic heart failure (ClinicalTrials.gov identifier: NCT01807221).
In summary, in patients with systolic heart failure and chronic kidney disease, the ARTS trial demonstrates a remarkable reduction of hyperkalaemia and worsening renal function with the novel non-steroidal MRA BAY 94-8862 as compared with spironolactone. These exciting results suggest that novel MRAs with improved tissue selectivity and fewer side effects are on the horizon, enabling even broader applications of MRAs in cardiovascular and other diseases.
Conflict of interest: J.B. reports grants and personal fees from Pfizer, personal fees from Novartis, personal fees from Medtronic, grants from Sanofi Aventis, and grants from Bayer, outside the submitted work.
The opinions expressed in this article are not necessarily those of the Editors of the European Heart Journal or of the European Society of Cardiology.
- Published on behalf of the European Society of Cardiology. All rights reserved. © The Author 2013. For permissions please email: firstname.lastname@example.com


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The gateway to Museum Victoria's on-line education resources. Includes online Projects for students of all ages, based on the museum's research programs and collections.The U.S. Department of Education does not accredit educational institutions and/or programs. However, the Secretary of Education is required by law to publish a list ...A live-in weekend and post weekend program for married couples. The emphasis is on a new technique of communication between a husband and wife. Seminars offered in ...Franklin D. Roosevelt Presidential Library and Museum National Archives 4079 Albany Post Road | Hyde Park, NY 12538 1 (800) FDR-VISIT or (845) 486-7770Startup Weekend is a global network of passionate leaders and entrepreneurs on a mission to inspire, educate, and empower individuals, teams and communities.1/24/2015 · Hear the Weekend Edition Saturday program for January 24, 20151/3/2015 · Hear the Weekend Edition Saturday program for January 3, 2015Designed for executives and located just outside Chicago, Benedictine's doctoral program integrates leadership, organizational change, and sustainability.NSU is a nonprofit, independent research university with a main campus in Fort Lauderdale, Florida offering undergraduate, graduate and professional degrees.Brown v. Board of Education of Topeka, 347 U.S. (1954), was a landmark United States Supreme Court case in which the Court declared state laws establishing separate ...
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Seattle, WAUSA
June 11, 2012
A sad and terrible portmanteau of the words "pony" and "bro", meaning yet another gleeful attempt by male fans of MLP:FiM to protect their precious masculinity from the unblinking Flash-drawn stare of sexuality-challenging pastel sparkle-ponies. Good luck with that, fellas. You're still "pony fans" to me. Don't call me a "pegasister". I'm just a pony fan, too.
I can re-carbonate flat beverages using merely two straws and my own nose.
Rarity is the best pony, Luna is the best princess... and Chrysalis is the best queen.
Better known as Gemini Star in pony-type circles this hat-wearing, star-staring, hoof-bearing winged freak is not only the publications lead for Everfree NW, but also somewhat a professional pain in the butt. What a character.
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Black Women in Politics: From Social Mobilizing to Elected Office
When it comes to civic participation and mobilization, black women are leading the way. But they remain severely underrepresented in electoral politics. Read more »
4 Reasons Why Student Athletes Are Political Front-Runners
While Title IX prevents sexual discrimination in all areas of education, the law is best known for ensuring gender equity in women's athletics. The critical law has empowered millions of […] Read more »
National Mentoring Month: Why Sponsorship Matters for Women in STEM
Although both mentoring and sponsorship can improve women's recruitment and retention in STEM, AAUW's "Solving the Equation" research report suggests that sponsorship may be uniquely beneficial. Read more »
Make the Most of Your AAUW Student Organization Meetings
Do you ever find yourself wondering what else you can do during your student organization meetings? Never fear; here are ten ideas to get you excited. Read more »
Your Guide to Awkward Family Conversations about Sexism
What do you say when your sister says, "I wouldn't vote for a woman president. They're too sensitive!" Read more »
When States Fail at Political Equity, Women Students Step Up
There are still a few states that have never elected a woman to either the U.S. House or U.S. Senate. Elect Her attendees are working on fixing that. Read more »
4 Things I Learned from My Mother Working in STEM
The working moms I've met worry — about how many hours they worked, about how the demands of their jobs affected their children, and about how having children affected their work. My own mother worked tirelessly and inspired me daily. Read more »
The Logic for Leaving: An African American Woman in STEM Discusses Challenges
Shaneen Harris spent nearly 20 years in information technology. But then she left the field entirely. Among the reasons? Gender bias and a hostile workplace environment. Read more »
On Capitol Hill, Yale Biophysicist Addresses STEM Gender Bias and Solutions
Espinoza Sanchez, a 2013–14 AAUW International Fellow, is used to pushing against stereotypes and assumptions about women in STEM. Gender stereotypes pervade hers and her colleagues' experiences at the Pollard Lab at Yale University, where she is a doctoral candidate. Read more »


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Sheriff's department seeking woman accused of using stolen credit cards
The San Diego County Sheriff's Department is asking for your help to identify a woman wanted for using stolen credit cards at several North County stores.
alan: The writer forgets about (low energy) Jeb who was a shoe in and sixteen others bit the dust with the media trying everything they could to screw Trump over. He has one hundred times the experience in business than all the other opponent he faced and she faced only Sanders really who the DNC ruined before a first vote was cast. In the Nixon Kennedy debate the media predicted a landslide for the previous VP and opps...it went the other way. I am confident Trump will wipe Hillary out regardless of the spin before or after the debate. Trust is a big deal and Hillary has lost that with the real voters not the rigged polls. Wake up sheeple...the media is about to get it's #$%$ kicked. And George Soros...well, you money has been wasted.


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匹配项: article X
Do you know the IBM Systems Magazine web pages ?
The IBM Systems Magazine web pages have good articles around the mainframe. They have several categories such as Administrator, Business & Strategy, Trends, Storage, Case Studies. Under Trends you can find topics related to z/VM and Linux on z...
Do you know the IBM Systems Magazine ? Next blog entry on May 30, 2016
Ingolf24 标签: vse article linux ibm_systems_magazine 897 次访问
I don't know, if I ever posted any information about the IBM Systems Magazine. It provides articles related to the mainframe. In the most current issue (May / June 2016) you can find an article about the new IBM z13s processor, page 11. It's related to...
z/VSE technical article: z/VSE release and hardware upgrade
Last November I informed you about a z/VSE migration technical article. The blog entry is here . Just a few days ago we updated that article and changed the title from z/VSE migration to z/VSE release and hardware upgrade. I think, the new title...
New z/VSE article: Mobile Integration of CICS TG and CICS TS for z/VSE
Ingolf24 标签: cics_transaction_gateway cics article documentation white_paper vse mobile 1,791 次访问
We just published a new article on our documentation web pages. The article describes how to setup a mobile platform with access to the CICS Transaction Server for z/VSE. The title of the article is "Mobile Integration of CICS TG and CICS TS for...
New z/VSE article: From virtual tape to tapeless installation
Ingolf24 标签: etj vse enterprise_tech_journal tape-less installation article 1,657 次访问
The latest Enterprise Tech Journal (ETJ - May 2015 issue) includes an article written by my colleagues. The title of this article is "z/VSE: From virtual tape to tapeless installation". The article gives some details about one of the key functions...
Accelerate the design and development of Java Enterprise Applications
AcdntlPoet 标签: java dw agile developerworks development article rational-client-support rational how-tos 2,222 次访问
Accelerate the design and development of Java Enterprise Applications - This article shows how to apply Model Driven Architecture principles to accelerate the design and development of Java Enterprise Applications that use mainstream technology, such as Java...
Technical article and (LVC) presentation available: Getting started with mobile development for z/VSE
Ingolf24 标签: mobile vse live-virtual-class presentations lvc article 1,834 次访问
Today I have some reading for the weekend. We just made a technical article available on our documentation page. It provides some insight on how to connect from mobile devices to z/VSE resources. The title of the article is "Getting started with mobile...
Lego version of a mainframe
Most of us know Martin Truebner from conferences such as GSE and WAVV. On those conferences he showed us the Lego version of a zEnterprise 114. Martin transformed the z114 model into a working mini "mainframe". Now an article about Martin's...
New edition of the mainframe weekly is out
Ingolf24 标签: article vse mainframe_weekly 1,237 次访问
My last post about the the "IBM Mainframe Weekly" was already 6 month ago. I think it's time to remind you about that newsletter again. It has links to white papers, social media, articles, videos, and information all around the mainframe. The...由 Ingolf24 于 修改
Java web services in the CICS Liberty JVM server
Giovanni Creato 标签: web_services howto java article liberty jvm_server 1 条评论 3,503 次访问
The aim of this article is to show how you can use the CICS Liberty JVM server to expose an existing CICS program as a web service using the JAX-WS specification. This article is intended for Java developers and system programmers that have little knowledge of...由 Phil_Wakelin 于 修改
z/VSE's Parallel Access Volume support: Article on the web
In February I already had a blog post related to z/VSE's Parallel Access Volume (PAV) support. At that time we just released new PTFs with PAV improvements for z/VSE 4.3 and 5.1. Those PTFs are integrated into z/VSE 5.2. The blog entry is here . Mid of...
New Enterprise Tech Journal available with z/VSE and Linux on System z articles
The October / November 2014 issue of the Enterprise Tech Journal (ETJ) is available. ETJ articles are targeted to mainframe users and their IT environments. In this issue you can read a z/VSE article. It's title is "Parallel Access Volumes: Tune Your...由 Ingolf24 于 修改
Quick start CICS Explorer projects for "Cloud Enabling CICS"
This article makes it easier for you to try out the examples in the new IBM Redbooks publication Cloud Enabling CICS (SG24-8114-00). The IBM Redbooks publication explains how you can cloud enable your CICS environment with step-by-step incremental...由 D_Harris 于 修改
z/VSE Article on security in Enterprise Tech Journal
A few weeks ago the August/September 2014 issue was published. There are lots of articles around the mainframe. One article is about security with z/VSE, written by a z/VSE colleague. The title is "Transport Layer Security Version 1.2: Gaining Ultimate...
Introduction to IBM DevOps Practices 社区博客
BruceMacIsaac 标签: adoption-framework devops practices article 4,261 次访问
Abstract This article summarizes why adopting DevOps is critical to fast, lean Enterprise Software Delivery, and describes how the IBM DevOps practices can help you adopt DevOps. Introduction DevOps is an enterprise capability for efficient continuous...
来自博客: DevOps Community由 BruceMacIsaac 于 修改
Developing behavior extensions for InfoSphere MDM v11 社区博客
Dmitry Drinfeld 标签: mdm-server mdm preview mdm-workbench osgi article behavior-extension mdm11 1 条评论 3,879 次访问
Developing behavior extensions for InfoSphere MDM v11 Special thanks to Stephanie Hazlewood for providing guidance as well as content for some of the sections of this article! Executive Summary Many established organizations end up having unmanaged master...
来自博客: MDM Developers由 jtonline 于 修改
Articles and news about the mainframe
Ingolf24 标签: etj mainframe_weekly enterprise_tech_journal vse article 2,276 次访问
Today it's raining all day. Therefore some recommendations for reading: The June / July 2014 issue of the Enterprise Tech Journal (ETJ) was just published. It also contains an z/VSE article from one of my colleagues. It's title is "Monitoring Your...
Using the IBM MQ classes for Java with a CICS JVM server
Phil_Wakelin 标签: article howto mq eclipse jvm_server liberty 1 条评论 5,292 次访问
This article describes how to deploy a Java application that uses the IBM MQ classes for Java into a CICS OSGi or Liberty JVM server Requirements To follow the setup in this article you should already have performed the following: S etup CICS to access...由 Phil_Wakelin 于 修改
The CMCI RESTful API: Part 1 - Talk to CICS using the Browser
IsabelArnold 标签: blog howto cmci http article restful cics_explorer 4 条评论 5,639 次访问
Many of us have used CICS Explorer to manage CICS. But did you know that you can use the underlying CICS Management Client Interface (CMCI) from your browser (or any other HTTP client)? The CMCI request structure consists of an HTTP header with a method (GET,...由 Phil_Wakelin 于 修改
Exporting CICS Explorer connections using Open Office spreadsheets
Giovanni Creato 标签: article blog cics_explorer 3,127 次访问
Abstract: CICS CMCI connections can only be defined manually in CICS Explorer. This is suitable if you have to create a small number of connections but does not fit if you have to define a large number of connections. This document will show you how to...由 Phil_Wakelin 于 修改
New Article: Getting started with Nmap for system administrators
I had a new article published on IBM developerWorks today: Getting started with Nmap for system administrators
JAX-WS and JAXB support in CICS TS V5.2 Liberty JVM server
Mark Cocker 标签: web_services article java liberty blog jvm_server 3 条评论 5,995 次访问
[7/Oct - article updated to refer to CICS TS V5.2 and some WASDev links updated] CICS TS V5.2 includes the latest WebSphere Application Server Liberty Profile (WLP) V8.5.5 that provides features for the Java API for XML Web Services...由 Phil_Wakelin 于 修改
Integrating IBM Health Center and CICS Explorer
Phil_Wakelin 标签: java jvm_server health_center article 2 条评论 5,527 次访问
This article shows how the IBM Health Center can be easily installed into the CICS Explorer and used to create customized perspectives for monitoring CICS JVM servers. Together these two tools provide a powerful platform for profiling CICS Java applications,...由 Phil_Wakelin 于 修改
RDz Server Health Checklist document available
mquimby 标签: whitepaper top-content rdz hot-support-content article rational-client-support 3,507 次访问
Check out this newest knowledge collection from Rational Client Support, a RDz Server Health Checklist by support engineer Roger Newton! Title: Rational Developer for System z Server Health Checklist Abstract: The IBM...由 mquimby 于 修改
Writing RESTful web services using a CICS Liberty JVM Server - Part 2
DanielFitzgerald 标签: web_services article liberty json jvm_server blog restful mobile 1 条评论 10,004 次访问
Writing RESTful web services using a CICS Liberty JVM server - Part 2 Introduction My name is Daniel Fitzgerald, I'm a trainee software developer in the CICS team based at IBM Hursley UK. I've been working for the last six months on the Mobile...由 Phil_Wakelin 于 修改


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I want to be sure folks don't think my ongoing discussion themed "No Contract Vehicles Needed" is me saying you don't need a contract vehicle to generate sustainable business in the federal sector, that would be silly. However, for everyone that believes (and professes) having a contract vehicle is the only way to do business with the government, this blog post, among others, is me saying "I beg to differ."
Uncle Sam has competitively and non-competitively awarded more than $90 billion in goods and services in FY13 where the Award/IDV Type referenced indicates a buy that did not tap a GSA Schedule, BPA, GWAC or other Indefinite Delivery Contract.
With that being said, this entry is the setup for a complimentary one-hour webinar we'll be hosting for our members and partners this Friday (May 31st at 11:00AM and again on Wednesday, June 5th at 3:00PM) to give them a deeper dive into exactly how the Department of Defense awards contracts this way, how much they spend, to what extent they compete these buys and what they buy when they do award this way.
Standard stuff, right? Okay, here we go.
Taking into consideration DoD contract data is delayed ninety (90) days for reasons of operational security, you can assume the "actual" numbers are significantly greater than what I'm reporting here. We'll know for sure in ninety days! Additionally, I'm only going to cite information about competitive buys (i.e., Full and Open Competition, Full and Open After Exclusion of Sources and Competed Under Simplified Acquisition Procedures). If you were to go back and add in all of the follow-on and non-competed buys, these numbers would jump considerably. Not that they aren't already impressive enough.
Part of the reason I'm talking about this is simply to assist with radar calibration, and not mine. That is, many companies seem to get wrapped around their own axles looking for specific types of business, effectively ignoring other viable opportunities right in front of them. Think about it. If you have a GSA Schedule, are you going to walk away from an opportunity just because the agency is not utilizing the FSS to make the buy? Some of the answers I have gotten over the years might surprise you.
Then there is what I call the "snooty" factor, which applies to companies who believe they understand Simplified Acquisitions and want nothing to do with them because they equate them to Micropurchases (buys for goods and/or services up to $3K always paid via GSA SmartPay).
They don't know what they are missing.
Not only are buys made using Simplified Acquisition Procedures potentially much, much larger than Micropurchases, there is also an inherent (FAR-based) preference for awards to small businesses. While according to the FAR, every purchase order issued is a Simplified Acquisition buy, not every Simplified Acquisition buy is issued via a purchase order. In the case of DoD YTD, they have awarded in excess of $1 billion in purchase order awards.
Adjusting your radar for market research means enhancing your context. Without the ability to understand what you are looking at, you could have every piece of information needed to score your next win right in front of you, and you would never know it.
Over the next several weeks, we'll be spending time looking at DoD spending and digging into the various services and agencies. If your business is in CYBER/IT, Professional Services (Non-IT) or Construction and Facilities Services, tune in for an upcoming simulcast of "No Contract Vehicles Needed" as we host three sessions each month and highlight spending related to those offerings.
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9/28/2016Business Over Breakfast™ Tysons (9/28/16)
10/3/2016 » 12/1/2016Competitive Intelligence Bootcamp for Government Contractors™ (CIBOOT1016)
10/5/2016Business Over Breakfast™ Tysons (10/5/16)
10/12/2016Business Over Breakfast™ Tysons (10/12/16)
9/12/2016Major GSA schedule update is a parity play (and really risky, too!)
9/12/2016When Large Government Contractors Punch Down
9/12/2016Low-Hanging Fruit are a FASA-nating Opportunity!
9/12/2016Quick Guide to Product and Service Codes in Government Contracting


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>>>>> "Christoph" == Christoph Hellwig <h...@lst.de> writes:
Christoph> Switch the arcmsr driver to use pci_alloc_irq_vectors. We Christoph> need to two calls to pci_alloc_irq_vectors as arcmsr only Christoph> supports multiple MSI-X vectors, but not multiple MSI Christoph> vectors. Christoph> Otherwise this cleans up a lot of cruft and allows to use a Christoph> common request_irq loop for irq types, which happens to only Christoph> iterate over a single line in the non MSI-X case. Ching: Please test and review. Thanks! -- Martin K. Petersen Oracle Linux Engineering -- To unsubscribe from this list: send the line "unsubscribe linux-media" in the body of a message to majord...@vger.kernel.org More majordomo info at http://vger.kernel.org/majordomo-info.html


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The Ravens were unable to keep their top priority in free agency.
Free-agent inside linebacker Dannell Ellerbe reached an agreement in principle with the Dolphins, according to the Baltimore Sun. That means both of the Ravens' starting inside linebackers from the Super Bowl, Ellerbe and Ray Lewis, won't be returning next season.
Ellerbe was the Ravens' best defensive player by the end of the team's Super Bowl run. This season, he finished second on the team in tackles (89) and sacks (4.5). Ellerbe is athletic and aggressive, who is just hitting his stride as an every-down player.
There was always a chance that the Ravens wouldn't be able to retain Ellerbe, but it's a surprise to see where he landed. The Dolphins were never heavily linked to Ellerbe. The Browns and Bills were considered the favorites to take him from Baltimore.
Inside linebacker now becomes a priority for the Ravens. Even the status of Jameel McClain, a three-year starter at inside linebacker, is uncertain after a spinal cord contusion ended his season last year.
The Ravens have now lost Ellerbe and Paul Kruger within the first two hours of free agency. Of their own free agents, the top priority now becomes safety Ed Reed.


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Conductivity Meters Applications
Electrical Based Tomography Systems for Multiphase Flowby Industrial Tomography Systems plc (ITS) based in Manchester, UNITED KINGDOM
Multiphase flows are complex and unpredictable however they have a significant bearing on the safety, costs and revenues of many processes – particularly in oil and gas, but also in aerospace, chemicals and other sectors.
Water Data Management Solution for Groundwater Monitoringby KISTERS group based in Aachen, GERMANY
Deployed across all relevant sectors including landfill security, well field monitoring programs, pumping tests, and drinking water supply, KISTERS solutions can be used to measure groundwater data.
Multiparameter Monitoring for Scientific and Academic Researchingby Valeport Ltd based in Totnes, UNITED KINGDOM
Research programmes demand both technology and affordable products to cover studies from rivers to full ocean depth. Valeport have gained significant knowledge through close collaboration with some of the worlds leading institutes. A clear example of this is our CTD sensor fitted to the seal tags of the Sea Mammal Research Unit (SMRU) of St Andrews University, Scotland as they monitor marine mammal behaviour within their oceanic environment, by obtaining oceanographic quality CTD casts.
Measurement solution for AD-211 VOC speciation in natural gas, syngas & gasificationby Protea Limited based in Middlewich, UNITED KINGDOM
Composition of Natural Gas, Syngas via VOC Speciation
The composition of fuel gas is important in order to determine calorific value and also to detect any unwanted contaminants in the gas. Online analysis is important in order to give real-time and direct action on issues.
Conductivity analysis for the municipal water and waste facilitiesby IC Controls Ltd. based in Orangeville, ONTARIO (CANADA)
Biogas measurement for the waste to energy industryby Kurz Instruments, Inc. based in Monterey, CALIFORNIA (USA)
In a recent project and the subject of this paper, Kurz engineers conducted a study that lead to a unique, new design that allows thermal flow meters to perform accurately within a wet digester gas environment. The testing environment applies to landfill and digester applications.
Electrical Based Tomography Systems for Crystallisation/Precipitationby Industrial Tomography Systems plc (ITS) based in Manchester, UNITED KINGDOM
Crystallisation is a key reaction in pharmaceutical and other process sectors. The combination of two ionic species in solution to form a solid frequently produces a strong change in electrical properties which can be tracked using ITS electrical resistance tomography sensors. Sensor arrays are produced on two different formats:
Industrial water Nickel Lateriteby PuriTech Ltd based in Herentals, BELGIUM
Lateritic nickel ore deposits are surficial, weathered rinds formed on ultramafic rocks. Nickel laterites are a very important type of nickel ore deposit, they comprise 73% of the continental world nickel resources. They are growing to become the most important source of nickel metal for world demand. Nickel is a hard, silver white metal that has industrial applications related to its strength, corrosion resistance, high ductility, good thermal and electrical conductivity and catalytic properties. Its primary use is in manufacture of stainless steel, steel alloys and superalloys. The Nickel purification process is very complex of which a few are based on ion exchange, each taking care of a part of the full process cycle.
Ultra pure water treatmentby Lenntech Water Treatment based in Delft, NETHERLANDS
Ultra pure water is mainly used in the semi conductor and pharmaceutical industry. Because of the continuing miniaturilisation in the semi conductor industry, the specifications become more strict every year. Ultra-pure water contains by definition only H20, and H+ and OH- ions in equilibrium. Therefore, ultrapure water conductivity is about 0,054 uS/cm at 25oC, also expressed as resistivity of 18,3 MOhm.
Conductivity measurement in the production of ultrapure waterby WTW - a xylem brand based in Weilheim, GERMANY
Water quality monitoring systems for feedwater, storm & condensate industryby SWAN Analytische Instrumente AG based in Hinwil, SWITZERLAND
The most important parameters in Water/Steam Cycles such as Cation conductivity, dissolved oxygen and pH are available as pre-assembled and factory tested units. Dedicated analyzers for sodium, silica, phosphate and hydrazine are also factory tested and calibrated for immediate operation.
pH value and conductivity measurement for power plantsby Metrohm AG based in Herisau, SWITZERLAND
The pH value and the conductivity have to be determined quasi-continuously at numerous locations in a power plant. The pH value is a key parameter to control the amount of lithium hydroxide that has to be added to the primary circuit of a pressurized water reactor; in water steam circuits, the pH value controls the amount of added amines. The conductivity indicates the amount of dissolved minerals. It is a measure of the water purity and is one of the most important parameters for any chemical control program in a power plant. It is determined at numerous sampling points in the power plant, for example, in the cooling water circuit, in feed and makeup water, at the outlet of the condensate pump, and in the primary circuit of a pressurized water reactor.
Laboratory Analytical - Moisture Content Determinationsby Mettler - Toledo Int. Inc based in Greifensee, SWITZERLAND
The moisture content influences the physical properties of a substance such as weight, density, viscosity, refractive index, electrical conductivity and many more. Chemical, thermogravimetric or loss on drying techniques are used to determine this content.
Water quality monitoring systems for wastewater & effluents monitoring industryby SWAN Analytische Instrumente AG based in Hinwil, SWITZERLAND
Instruments for monitoring the aeration-process, nitrification and de-nitrification; chlorination and de-chlorination; as well as the final discharge into the environment.
Multiparameter Monitoring for the Defense Industryby Valeport Ltd based in Totnes, UNITED KINGDOM
Our COTS (commercial off the shelf technology) approach to military requirements ensures some of the very best sensor technology available to measure speed of sound, temperature, depth, conductivity, salinity and density on both surface vessels and submarines. Valeport equipment in both standard and bespoke formats is in regular operational use by many Navies worldwide. Standard equipment can be re-packaged to suit your needs and replace legacy equipment.
Water Testing for Horticultureby Myron L Company based in Carlsbad, CALIFORNIA (USA)
Modern growing practices include scientific evaluations of soil, water, fertilizers, diseases, etc. While some tests are best performed by a laboratory, others can be easily conducted on location, saving time and money. Three tests in particular, EC, pH, and ALKALINITY, can reveal valuable information about water quality, soil salinity, and fertilizer concentration. MyronL Company's portable AGRI-METERS provide you with a simple, fast, and accurate means of testing these parameters.
Fountain Solutionsby Myron L Company based in Carlsbad, CALIFORNIA (USA)
Accurate fountain (dampening) solution concentration control is essential for consistent, high-quality results in lithography. Low concentration can cause drying on the non-image area of the plate resulting in tinting, scumming, blanket piling, etc. High concentrations, on the other hand, bring about over-emulsification of the ink. This results in weakening of color strength and changes in ink rheology (body and flow properties). Correct concentration will allow the non-image areas of the plate to be appropriately wetted.
Laboratory Weighing - Moisture Content Determinationby Mettler - Toledo Int. Inc based in Greifensee, SWITZERLAND
The moisture content influences the physical properties of a substance such as weight, density, viscosity, refractive index, electrical conductivity and many more. Chemical, thermogravimetric or loss on drying techniques are used to determine this content.
PEHD membrane sealing systems for storage areasby ELD Environmental Leak Detection GmbH based in Berlin, GERMANY
Areas used to store substances which could represent a hazard if they escape into groundwater must also be leakproof in case accidents occur.


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Child of eternity
When I was a kid, my father more than once threatened to get a baseball bat and etch "Steven's Attention Getter" into the wood. He told and retold a story about a farmer plowing a field behind a stubborn ol' mule, the punch line of which had to do with the stick the father carried on the plow — the mule's "Attention Getter."
Ask around. A ton of men my age had a father who employed this parable about their attention-deficit sons. As an adult, I discovered some of those men were always confident it was merely a wry, editorial commentary. Hyperbole. A joke.
Can't say that had ever occurred to me. Who knew?
On the one hand, my father was correct, as is anyone who ever braved the waters of rearing a child. "Baby brains," my kids' mother used to call it. "Hamster brains," was my somewhat less flattering description. We both meant the same thing: Children are easily distracted. As a father, I would think "Go brush your teeth" was a fairly simple, self-explanatory directive. But when you are 5 years old, there are multiple, alternative universes to be explored in the 50 feet between the couch you were sitting on and the toothbrush in the bathroom down the hall. Lots can happen. And does.
Yet, there is an irony in this parental observation. What I notice about children — certainly my own children — is their attention-deficit was caused by their singular passion and ability to pay attention! Do you see the twist?
Children are born wide-eyed and filled with wonder. The chief reason they have difficulty following a single, linear plan of attack is because they tend to see all the possibilities. And want to. They struggle to do one thing because they delight in paying attention to everything!
I remember looking into the eyes of my infants and later toddlers, watching them absorb what, for me, were the random details of their surroundings and thinking to myself, "They still remember eternity." If you are loathe to take that literally, then hear it this way: Infants and toddlers have not yet been socialized to restrain, scorn and censor their imaginations in service to becoming well-functioning cultural beings.
Now that I'm older, I find myself circling back to the mandate: "Steven! Pay attention!" But for very different reasons and motives. Not to dodge and duck metaphorical or actual blows from a frustrated, impatient father. No; the new motive is at once more urgent and holy. The universe isn't frustrated with me. More, it's incredulous: How in heaven's name did this mortal doofwad ever get the idea that he has time? How and why does he continue to construct demonic fill-in-the-blank sentences like "When I (effect some ideal state of affairs) then I will (give my complete attention to what really matters)."
My teacher once said to me, "In heaven, there are only two relevant questions — where am I, and what time is it. And, there are only two correct answers: I'm here, and it's now."
I remember sitting in that class room, smiling at the image of me rummaging a glove box for a highway map, wrestling it open and finding only block letters saying "Here." Or asking a passerby, "What time is it?" And the answer would be, "Now o'clock. You can set your watch by it."
The mystics call this perspective The Eternal Now. It's an idea inviting us to (what I call) Radical Presence. I said it this way once in a song:
We live as if we're gonna live forever
The rabbit sleeps as life goes plodding by
There's what there is and then no more
The door stays open twenty-four
Hours less than this time yesterday
At age 6, it was important to turn my attention away from Eternity so I could remember to put on pants, tie my shoes and flush the toilet. Now, a few months away from 56, I find a renewed urgency to remember eternity once again. I find myself rocking in this paradoxical lullaby: Very little that is important requires hurrying up, and … there is not one moment to waste. I'm here. And it's now.
The next time you find yourself killing time, ask yourself: Isn't it more likely that time is killing you?
Steven Kalas is a behavioral health consultant and counselor at Las Vegas Psychiatry and the author of "Human Matters: Wise and Witty Counsel on Relationships, Parenting, Grief and Doing the Right Thing" (Stephens Press). Contact him at email@example.com.
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21 Ways Steak 'n Shake Turns Dreams Into Reality
"In sight, it must be right." Get excited, Los Angeles.
1. Steak 'n Shake is famous for steakburgers, which are what regular burgers wish they could be.
Steakburgers are the delectable, scrumptious morsels from your burger fantasies.
2. They've literally been around for 80 years.
3. You can multiply layers to make a behemoth of a sandwich.
4. They make their own freaking pepper sauce.
5. Also, they have a ton of shakes. Steaks and shakes. Get it?
Steak 'n Shake has side by side shakes. That's two DIFFERENT shakes in ONE GLASS at the SAME DAMN TIME.
Yes, this is real life.
6. Let's talk about fries for one second. They are delicate, crispy, and SO delicious.
7. And you can put cheese on them, turning a perfect thing into an actual dream come true.
8. The dining experience is super retro, just as all truly amazing things are.
9. The employees wear bow ties. Why? Because they are professionals, that's why.
10. Steak 'n Shake has happy hour, and who doesn't enjoy a good happy hour?
11. Steak 'n Shake gets creative with their menu so customers are never bored.
13. Never limited by the English language, Steak 'n Shake came up with "Takhomasak," their own word for "take-out."
14. Their patty melts are fantastic layers of magical yumminess.
17. Their desserts are all Sugarplum Fairy-approved.
18. Steak 'n Shake's late night menu is the cure for any nightmare.
19. And if you're going through a frugal phase, they have a ballin' value menu.
20. People in the midwest are basically born loving Steak 'n Shake.
21. Steak 'n Shake + Cali sunshine = everything you've ever wanted.
Soon the dream of Steak 'n Shake will become a reality for Los Angeles. Rejoice!
This post was created by a user and has not been vetted or endorsed by BuzzFeed's editorial staff. BuzzFeed Community is a place where anyone can post awesome lists and creations. Learn more or post your buzz!
- Golf legend Arnold Palmer has died at 87. Known as "The King," his unusual style and charisma changed the game.
- Monday night's US presidential debate may be the last hope for environmental activists who want climate in the national conversation.
- US officials have determined al-Qaeda likely influenced suspected New York City bomber Ahmad Khan Rahami.


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Cardie is a 8 yr old grade quarter horse mare. Super shapely, 15.1h and acts like a gelding. Finished barrel & pole horse, if you can ride - you can ride…$3,000
Toscana is a 19 year old, ex AA show hunter, broodmare or pleasure horse. Toscana aka Sally was a 3'-3-6 AA show hunter and is now being sold as a broodmare…$3,500
Xemino is an APSL approved bay Lusitano stallion. Owned by Sarah Macone, he stands and trains at Rancho Bayo in Georgetown, TX. He is almost exclusively…Stud Fee: $1,500
2 year old grade quarter horse filly to good home only. She is a great project horse that has been started under saddle. I can get on her bareback with…$500
Challenge enrolled$5,500
Located in Austin, TX 17.2 hh young prospect mare. Has been to multiple shows and placed very well in the greens. Will be best used as a hunter/derby/equitation…$20,000
CUTTER Offering "Cutter", a beautiful sorrel and white Tobiano filly with a foal date of February 25th. This cute filly should be an excellent barrel…$2,200
LENA "Lena" is a show stopping chestnut and white Tobiano filly with a foal date of February 16th. This filly has a beautiful head and very good confirmation…$2,000


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The Cowboys struggled on defense after making a schematic switch to a 4-3. Should they stick with it in 2014?
Agree with someone's comment? Vote for it to make the Debate Highlights section. Disagree with a comment? Reply and voice your opinion. Happy Debating!Add Comment
We should stick with the 4-3...It's Sean Lee's Defense now.Full Comment »
It was bad enough to switch from the 3-4 to the 4-3 in the first place. To make another switch one season later is insane.Full Comment »
The 4-3 is good. But the Tampa 2 must leave. The base 4-3 or an attacking 4-3 would work much better than the Tampa 2Full Comment »
I honestly feel bad for Romo for playing with this team his whole career. Get him a solid defense and give him a chance to win at least one Super Bowl...Full Comment »
Hire MIKE ZIMMER from cincy!!!! I would say as HC but DC would b GREAT...install his system and bulk up the secondary...then we'd be SOLID!!!!Full Comment »
The 4-3 is what brought them their championships, and if I'm not mistaken, its also what brought the most recent Super Bowl champs their rings as well...Full Comment »


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The most important part about this picture is that Josh Hamilton cardboard cut outs exist and that Lee has already cornered the market on them by the time you finish this sentence.
The most important part about this picture is that Josh Hamilton cardboard cut outs exist and that Lee has already cornered the market on them by the time you finish this sentence.
The new rookie backpack for the Texas Rangers comes with a duffle bag in the shape of a fat horse. Robbie Ross rode it for a good 50 feet while 'Happy Trails' played last night before he realized just how far the bullpen is from our dugout.
(photo via Louis DeLuca, DMN)
Twitter reacts to Yu Darvish being voted as the final member of the AL All Star team over Jake Peavy of the Chicago White Sox.
Want NEED
Update: From the company making the shirts: You can pre-order the red through April 25th, and we are re-stocking the blue soon www.blacksheeplimited.com or www.shopblacksheeplimited.com
"Aside from a couple of ninth-inning hiccups by Joe Nathan, the Rangers boast both the best record and best run differential in the American League"
Seeing fans rush the field and get laid out by ballpark security is probably one of my favorite baseball traditions, right behind Take Me Out to the Ballgame and Derek Jeter having genital herpes.
If you missed it, it was in the 9th inning yesterday during Matt Harrison's CG 5 hit shutout. Two guys rush the field for no reason whatsoever. This dude got the shit knocked out of him.
(photo via AP)
Everything was Rangers and nothing hurt.
In the running for my favorite Rangers moment of the season. The best was Adrian's epic staredown at Elvis. Like "ARE YOU FUCKING KIDDING ME, SON?! REALLY?!"
Original via SB Nation (no clue who did the trollgaze2k12 edit):
But, 2 out of 3 is still a series win. Let's #dowork against the Mariners now.
David Murphy: Strong Tower (Kutless); Take My Life (Third Day)
Mitch Moreland: Homeboy (Eric Church)
Mike Napoli: Magic (T.I)
Neftali Feliz: Con Los Pies (Chimbala)
Brandon Snyder: Take it Outside (Brantley Gilbert)
Alexi Ogando: Latinos in Paris (Pitbull)
Michael Young: Heart of the City (Jay Z); Down (311)
Elvis Andrus: Al Se Eu Te Pego (Michel Telo); Lovumba (Daddy Yankee)
Ian Kinsler: Black Betty (Ram Jam); Superstition (Stevie Wonder)
Mark Lowe: Copperhead Road (Steve Earle)
Adrian Beltre: Pa Que Retocen (Tego Calderon)
Craig Gentry: Breakdown (Tantric); Mean To Live (Switchfoot)
Joe Nathan: Stand Up (Steel Dragon)
Josh Hamilton: Trust in Jesus (Third Day); Save Your Life (Newsboys); Blessing and Honor (Phillips, Craig and Dean)
Derek Holland: Paper Cut (Linkin Park)
(via: DMN)
I bolded the best ones. And of course Derek would have Linkin Park as his entry music just to troll everyone. Just look at him.
On a whim, Shannon and I got tickets to tonight's game before it completely sold out (protip: use the promo code DRPEPPER for $10 tickets). It's the MLB debut of Yu Darvish aka The Big Yunit aka Whirling Darvish aka YuDaMan aka Peanut the Kidnapper. I already own 2 Darvish shirts.
New goal for this season: Get interviewed by the Japanese media after a Darvish start.
(photo via AP)
8.1 innings. 10 strikeouts. 2 walks. No runs.
Against the fucking Yankees.
Welcome to the age of Darvish, Rangers fans. This shit is here to stay.
Happy partial season ticket day, everyone! I'm in Section 319 Row 9 for my 11 games this season (10 games + opening day).
If you look at the new away bullpen in centerfield, you'll see why I had to relocate. My section was the bleachers, which I would describe as a shanty town in the middle of the suburbs. But, I'm hoping that the 3B line in the first few rows of the upper deck will be just as accommodating and interesting as my previous section. Also, we got aisle seats!
And because of the deal on upper deck prices, I can squeeze in a few corner box seats for some random games throughout the year. 10 game packages go on sale to non-account holders next Monday. I suggest you get one. If you thought it was crowded last year, wait until the Yu Darvish train rolls into town.
Last year, Shannon and I attended a couples party where we all played card games and did shots before every game. We played in a couples vs couples format until we crowned a winner in each game. It was a super fun concept and we even had a list of different shots to make for each game. This was about a month after the World Series.
I'm still doing pretty bad at this point, but nowhere near the week or so after where getting out of bed was a chore. I still had nightmares and still had to try not to think about what happened. Like most days, I wore a Rangers shirt that night. I only mention this because it is important later.
At this party, we met another couple that the host met through online gaming. After the first game where he lost, it became clear that the male of the couple was an angry alcoholic. When he was losing a game, he would drink heavily and refuse to continue. Shit got awkward real quick. Upon asking the other couples there who knew him better, I find out that he is always like this. An embarrassing, angry drunk.
Flash forward to the end of the games and he's drinking a mostly whiskey filled solo cup while we're announcing the scores and standings. Out of nowhere, he decides to start bashing the Rangers in a way I've never seen before. Not from anyone with a casual knowledge about the game. No, this was an angry drunk just trying to get under my skin because I'm wearing a Nelson Cruz shirt (not that he can name anyone besides Josh Hamilton).
"You're in last place just like the Rangers."
"You can't win, just like the Rangers."
"You'll never win anything, just like the Rangers."
This is the closest I've felt to when my friends and I would get pushed down the stairs and called f*ggots for liking The X-Men in high school. Now, I'm amazed that I kept my cool here. I'm maybe a week into actual therapy for grief because of the World Series, but I didn't stab him. I just brushed it off as an angry drunk being angry. Later in the night, I served him 2 ounces of lemon juice, which I told him was a lemondrop.
Flash forward to the present. That couple is now married. I avoid parties that he goes to, knowing that he's just bad news. He still hits the bottle harder than Hank Jr. He still lashes out like a drunk badger. Shannon and I are still polite in social situations with them, out of respect for our group as a whole. My feelings for him are somewhere between not friending on facebook and hoping to see him on Intervention. Last night, I get the following message from him on facebook:
"Hey Lee it's <name>. We have mutual friends with <name>. I'm having a guys night out tomorrow going to the Ranger game.. I have an extra ticket if you would like to join us. I know you love our Rangers game starts at 7 pm."
Thankfully, Shannon and I are already going to the game, so I have an excuse. But seriously, what the hell? "Our Rangers?" Go fuck yourself, you bandwagon drunk. You don't deserve to call yourself a fan. I hope a foul ball puts you in a coma.
I hope that this picture makes its way back to the Japanese media in the coverage of Yu's first start. Maybe with some sort of caption like "Rather than the Western flair his fellow Rangers pitchers prefer, Darvish opts for a classic, all white outfit."
Also, I just noticed the cap gun and handcuffs. Epic choice, guys.
This is the new railing at Rangers ballpark that was raised following the death of Firefighter Shannon Stone. This view is from DMN writer Evan Grant sitting in a chair in around Section 5 (left field home run porch, aka where Shannon fell). He's 5'10", so you can imagine the viewpoint a 5'4" baseball blogger/squirrel fanatic might have. If I sit in the first 3 rows there, I'm missing the entire pitcher and strike zone. If I go back far enough to see it, I might as well pay $10 less per ticket and head to the second deck.
Another view of the new railing can be seen here.
Hey, it was only a few touchdowns, guys. Wait. That was a fucking baseball score?!
Your obligatory Yu Darvish fanboy post of the day:
7 innings pitched. 4 hits. 1 earned run. 9 strikeouts. 97 total pitches with 62 strikes. 20 out of the 27 batters faced took first pitch strikes.
With Darvish improving to 4-0, he becomes the first Rangers pitcher ever to win 4 out of their first 5 games pitched.
And yes, ladies. He's single.
(photo via: Reuters)
Today I came to a definitive agreement with the Texas Rangers.
The first press conference is in America, we would like to interview after returning home in Hokkaido.
I convey gratitude to the Japanese people, including Fighters and fans at the time.
Yu Darvish


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11 Weather Myths You Need to Stop Believing
Some untrue weather facts seem to ride out the storm. Find out which potentially life-saving info you've got wrong.
Today's weather is not your grandma's weather.
Myth: Big storms like tornadoes and hurricanes are the most deadly type of weather.
Myth: Lightning never strikes the same place twice.
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Myth: Doorways are the safest part of a house during an earthquake.
Myth: Alcohol will warm you up in cold weather.
Myth: Taping your windows shut during a hurricane protects your home.
Content continues below ad
Myth: Cold air makes you sick.
Myth: Lakes, rivers, and mountains can protect an area from a tornado.
Myth: Flash flooding can only happen near rivers and streams.
Content continues below ad
Myth: You can't get sunburned if it's not summer.
Myth: You'll get electrocuted if you touch someone who was struck by lightning.
Myth: You can safely drive through floodwaters.
Thanks! You're on our list.
And about to get a whole lot healthier.
Some people like to travel by train because it combines the slowness of a car with the cramped public exposure of an airplane.
Dennis Miller
I think my pilot was a little inexperienced. We were sitting on the runway, and he said, "OK, folks, we're gonna be taking off in a just few—whoa! Here we go."
Kevin Nealon
"I can't wait until your vacation is over." —Everyone following you on Instagram
A man knocked on my door and asked for a donation toward the local swimming pool. So I gave him a glass of water.
Comedian Greg Davies
Just found the worst page in the entire dictionary. What I saw was disgraceful, disgusting, dishonest, and disingenuous.
Client: We need you to log in to the YouTube and make all our company videos viral.
From clientsfromhell.net
My cat just walked up to the paper shredder and said, "Teach me everything you know."
"Just because you can't dance doesn't mean you shouldn't dance." —Alcohol
@yoyoha (Josh Hara)
My parents didn't want to move to Florida, but they turned 60 and that's the law.
—Jerry Seinfeld
Q: What do you call an Amish guy with his hand in a horse's mouth?
A: A mechanic.
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Natural Remedies for Dry Mouth That Will Make You Feel So Much Better
Difficulty swallowing, cracked lips, bad breath, tasteless food—they are all symptoms of dry mouth. While there are some serious causes of dry mouth, the condition is often harmless. But that doesn't make it less annoying. Here are some tips for how to relieve dry mouth at home.


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Skip to comments.Feds begin killing barred owls to help save spotted owl
Posted on 12/21/2013 4:47:51 AM PST by Innovative
An experiment to see if killing invasive barred owls will help the threatened northern spotted owl reverse its decline toward extinction is underway in the forests of Northern California.
The U.S. Fish and Wildlife Service said Friday that specially trained biologists have shot 26 barred owls in a study area on the Hoopa Valley Indian Reservation northeast of Arcata, Calif.
The service is spending $3.5 million over six years to remove 3,600 barred owls from sites in Oregon, Washington and California.
It is not unusual to kill one species to help a threatened or endangered one. Cormorants and sea lions are regularly killed to help salmon.
(Excerpt) Read more at foxnews.com ...
The liberal plan to save themselves is to wipe out conservatives, just like the gov't.
Sounds like 0bamacare.
despicable. along with allowing wind powered mix-masters to kill the American Symbol.
where is the leftist tree huggers on this??
no it is not about the tree hugging as much as being marxist.
To paraphrase someone who knows just a little about wildlife,
"It ain't logical. Hey man, it just ain't logical!
Add to it, Mamma Gump had it nailed.
"no it is not about the tree hugging as much as being marxist."
And control...
Can you imagine the outcry if people would start to kill these same owls because they cut down the trees where they nest or something?
But if they kill one species in the name of saving another, even though there is NO evidence whatsoever that there is any correlation, that's OK.
But I thought it was logging that was killing the spotted owl. That's what they said when they decimated the timber industry.
The Fish & Wildlife Service also issues "take" permits allowing utilities to chop up golden and bald eagles without penalties.
Is this why Hussein bought all that ammo?
An experiment to see if killing invasive barred owls will help the threatened northern spotted owl reverse its decline toward extinction ...
Wonder what they'd think about an experiment to see if killing invasive wolves would help the threatened livestock of ranchers reverse its decline in numbers due to wolf attacks.
"But I thought it was logging that was killing the spotted owl. Thats what they said when they decimated the timber industry.'
Well — it seems that was not the case...
"Major cutbacks in logging in old growth forest that spotted owls prefer as habitat have not turned around their population decline",
That's the problem when government gets involved, they don't do things based on evidence or logic.
Horrors! It's DISCRIMINATION!
We have in this country a population decline of white people because there are so many illegal immigrants coming in. Illegal immigrants are an INVASIVE SPECIES!
Nature is like the free market, let it function freely and it will sort itself out.
Sorta like cash for clunkers.
Destroying logging, farming, ranching, fishing .. jobs and local businesses - is the United Nations Agenda 21 goal.
Logging had nothing to do with the spotted owl situation. Rather Barred owls are the single biggest threat to spotted owl survival.
The Feds will waste another $3.5 million . While veterans get their pension cuts.
And what's the penalty if John Q. Public shot a barred owl?
Well first THEY KILLED LOGGING so now they need another victim....government doing what it does best...destroying
Another Federal jobs programs!!!!! These idiots do nothing useful. How come they aren't busy releasing more effin wolves???
Nasty creatures.
We have to kill them to save them.
Who knew Orwell was being literally prophetic......
Just think of the FedGov as a jobs program for wildlife biologists who cannot find employ elsewhere. If logging was still big there the logging companies would have to hire some....just a thought
We truly have the biggest bunch of fools, dupes, patsies, and useful idiots in power now. I'm nearly speechless.
How did the children get in charge?
They do this in the fish world, too. They kill all the fish in a Lake and reintroduce the supposed old species. They're so full of crap. And they get paid besides.
right....We were cutting down "their areas".
American Indians can kill them, too....Lot of bull.
Neat pic.
Government, picking winners and losers, once again.
They can simply throw them into the blades of the wind turbines along with the eagles. Barry said it's OK to do that.
"An experiment to see if killing invasive barred owls will help the threatened northern spotted owl reverse its decline toward extinction ..."
Invasive from where, China?
I'll be right over. (grin)
Knowing this feckless Big Government nanny state, the EPA will successfully kill off all the owls, but the lumber industry will still be banned from the empty forest.
I remember how the timber industry in Oregon and Washington was brought to its knees, two or three decades ago, "In order to save the Spotted Owl."
I have seen two just this past year in the neighborhood. Took a picture of one about 5 feet up on a branch.
The spotted owl isn't "endangered" either.
Just another excuse to control growth and productivity.
In five years they will find out the rodent population is soaring because of reduced owl predation. Then they will hire more people to shoot the rodents.
This is right out of Mao's economic planning book.
Then we turn to eagles killed by wind farms, "In to save the spotted owl the Sierra Club and the Wilderness Funds all stopped the lumber industry - but where are they today in an effort to save the eagle? Why is it that some animals or birds can be killed and nobody cares? But destroying jobs and raising the cost of housing is no problem for the well off environmental activists in San Francisco or Seattle?" TELL THESE STORIES AND SHAME THE PEOPLE who are ruining the American way of life.
The Barred Owls just need to start donating money to the Democrats.
That was the entire point of the spotted owl, destroy a thriving industry and replace it with Marxism.
Pray America is Waking
The Eagles need better lobbyist.
Wow...just wow.
Can I move in?
Don't worry...I would come locked, stocked and barreled!
Congrats on your great choices.
Disclaimer: Opinions posted on Free Republic are those of the individual posters and do not necessarily represent the opinion of Free Republic or its management. All materials posted herein are protected by copyright law and the exemption for fair use of copyrighted works.


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Brand ResearchAcura
Official Photos and Info2011 Acura TSX Sport Wagon
Acura gets a fourth utility-minded vehicle, and it could end up being the one we like best.
Short Take Road Test2010 Acura MDX
Best viewed and experienced from behind the wheel.
Long-Term Road Test Update2009 Acura TSX
Introduction: Beauty is as beauty does.
Short Take Road Test2010 Acura ZDX
Seven-year-olds think it's the Batmobile.
Car News2011 Acura TSX Sport Wagon
Another striking wagon is headed stateside.
Short Take Road Test2010 Acura TL SH-AWD Manual
Another six-speed hit from the makers of the Honda S2000 and Acura TSX.
Short Take Road Test2010 Acura RDX Front-Wheel Drive
Less money, less weight, same personality.
10Best Cars10Best Test Notes: 2010 Acura ZDX
First Drive Review2010 Acura ZDX
Acura goes a little, well, funny in the head. And we don't mind.
First Drive Review2010 Acura MDX
Aesthetic and technical upgrades bring Acura's range topper up to speed, just as the competition heats up.
Official Photos and Info2010 Acura RDX
The corporate beak is the most noticeable change, but a new front-wheel-drive version is more significant.
Short Take Road Test2010 Acura TSX V6
How does a big V-6 affect one of our longtime favorite sports sedans?
Comparison Tests2009 Infiniti G37 vs. BMW 328i, Audi A4, and Acura TL
Conspicuous consumption lite: Keeping the revs up and the ostentation down.
InterviewAcura Designers: ZDX Concept
Hondas luxury brand does more design work in the U.S. Will it help?
Official Photos and Info2010 Acura ZDX
This X6-fighter will vie for a slice of a still-undefined niche.
Auto Shows2010 Acura TSX V6
Holy torque steer! Acuras small front-drive sedan gets a 280-hp V-6.


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Kilronan Hostel
AddressInis Mor Galway Aran IslandsSee nearby area
For rates, enter dates/guests
Lonely Planet review
You'll see the Kilronan Hostel perched above Tí Joe Mac's pub even before your ferry docks at the pier, a three-minute walk away. Forty beds are spread across very clean four- and six-bed dorms. A terrace has fine harbour views and continental breakfast is thrown in.
Our independent authors have visited Kilronan Hostel and selected this as one of our recommended hostels in Inishmór.
Description provided by property
Located directly beside the pier on Inis Mór, Kilronan Hostel is the perfect place to stay to enjoy the magic of the Aran Islands. With stunning views of Kilronan Harbour and the Atlantic Ocean, our hostel is a stress-free zone where you can really feel at home!
At Kilronan Hostel, comfort and cleanliness are our priorities. We have small dorms, all en-suite, meaning you can stay in comfort at a very reasonable price. We have a spacious and well-equipped kitchen which is open all day for your use, as well as a cosy TV room and a fantastic outdoor seating and BBQ area.
Less than 1 minute walk to the supermarket and ATM and just metres away from all the best local pubs and restaurants, we have free Wi-Fi throughout the hostel and all rates include breakfast, towels and free tea/coffee all day long. We also offer free printing, free maps and free luggage storage.
So, why not visit Inis Mór to experience the magical charm of Ireland as it used to be!
Kilronan Hostel Environmental Policy:
At the hostel we are very environmentally aware. We recycle almost everything and we have separate recycling bins for glass, cans, cardboard and plastic as well as organic food. We would encourage everybody to please use this facility correctly.
We also use Airtricity electricity company which uses over 90% renewable energy. At the hostel we only use environmentally friendly light bulbs throughout the building.
PS: Double and Twin Rooms also available - check out Kilronan Apartments on Hostelworld!
Services & facilities
- Available
- Bicycle Parking
- Free Breakfast
- Bicycle Hire
- Board games
- Book Exchange
- Cable TV
- Common Room
- DVD's
Guest services
- 24 Hour Reception
- 24 Hour Security
- Cafe
Nearby places
Burke's Bicycle Hire
Patrick Burke is an expert on local cycling and can advise on routes that avoid crowds and reach seldom-visited ends of the island.
Aran Cycle Hire
Hires out hundreds of sturdy bikes, electric bikes and tandems, which it delivers to your accommodation anywhere on the island. It's at...
Aran Heritage Centre
For an informed appreciation of all three islands' history, geology and wildlife, stop in at the Aran Heritage Centre, just off the main...
Tí Joe Mac's
Informal music sessions, peat fires and a broad terrace with harbour views make Tí Joe Mac's a local favourite. Food is limited to a few...
Pier House
This is the best spot for lunch right in Kilronan – on the large terrace watching the ferries come and go while grazing your way through...