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The following 30 Fortune 500 companies paid no federal income tax in between 2009-10, according to a study by think tanks Citizens for Tax Justice and the Institute on Taxation and Economic Policy. To read the full report, click here.
30 Fortune 500 companies that didn't pay taxesPublished 2:04 PM CDT Mar 15, 2013
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John Gibson is on an NHL roster. Now, it's time to see if the 20-year-old goaltending prospect actually plays.
The Anaheim Ducks on Friday recalled Gibson, who led the United States to gold at the 2013 World Junior Championships. He'd posted a .915 save percentage in the AHL this season (good, but not great) and remains the assumed goaltender of the future for both Anaheim and the U.S. National team.
The move is a little surprising, though, if only because Jonas Hiller and Frederik Andersen are both healthy. Andersson, though, had been filling in for normal backup Viktor Fasth, who's out long-term with a lower-body injury, and hasn't been particularly good in his last three starts. He allowed three goals on 26 shots Thursday night against the Predators.
The problem is that Andersen, 10-2-0 on the season with a .923 save percentage and 2.07 goals-against, has only started three games since Dec. 21. He, like Gibson, is relatively young at 24, and could use regular action. So, sending him down to get a few starts in a row while Gibson hangs out with Hiller makes sense.
Or, why not, play him — the Ducks have a nine-point cushion in the Pacific Division. Might as well see what you have.

subset: commoncrawl


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Description: This is the T5403 breakout board, a fully calibrated barometric pressure sensor with an I2C interface. The T5403 sensor measures the absolute pressure of the air around. This pressure varies with both the weather and altitude. Depending on how you interpret the data, you can monitor changes in the weather, measure altitude, or any other tasks that require an accurate pressure reading.
The T5403 sensor consists of a piezoresistive MEMS pressure sensor element and an ASIC (application specific integrated circuit) with integrated temperature sensor, analog to digital converter ADC, memory and digital circuitry. Each breakout requires a supply voltage of 1.7V to 3.6V with a low current consumption of 790µA max and each pin (GND, VCC, SCL/SCLK, SDA/MOSI, MISO, RST/&SS, SEL, and EOC) broken out.
NOTE: SPI not supported. The datasheet T5400.pdf says: "I2C and SPI interface", but the comment of the code in the Github (Design Files) says: "NOTE: SPI is currently unsupported in the hardware." I would find it helpful if the product description page were annotated when you are aware that the datasheet is wrong.
NOTE: Only one T5403 per I2C bus, since the slave address is fixed at 0x77.
I wrote a Python script for T5403 + RaspberryPi . I cloned it from the Arduino example on Github. Please take it from here
I am using a picaxe micro-controller to get barometric pressure from the T5400. I have used I2C for other devices. I just changed slave addr to 0x77, but it didn't seem to help. I input 2 bytes, but first byte receives all ones, and 2nd byte all zeros.Any ideas?
Update on my post. I found the data sheet for T5403 with all the addresses of the REGISTERS. Now I'm wondering if I can't get RAW pressure reading because I have not filled in CALIBRATION registers.
Has anyone had any experience with using any of these bp sensors outdoors? I have to record bp and other environmental variables outside and my last sensor (MPL115A2 from Adafruit), corroded within 1-2 months even though they were very protected from rain and dew. I'm looking for a better version that is compatible with outdoor use.
Does anybody know the difference between this T5403 and the BMP180? I know the BMP180 also measures temperature, but I'd like to know if there is so much difference between the energy each one of them uses and then conclude if this is worth it. Thanks & Regards!
Originally it was supposed to be a SPI enabled sensor. But as it stands the minor difference is this sensor reports in Pa directly as opposed to hPA like the BMP180. But that is just a difference in multiplying/dividing by 100. There is a size difference in the IC (T5403 is smaller) but that doesn't help much when it's attached to a breakout.
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LEWISTOWN - Shirley E. Goss, 74, of Lewistown, died at 4:43 p.m. Sunday, May 18, 2014, at Ohesson Manor.
Born Feb. 2, 1940, in Juniata County, she was a daughter of the late Lawrence and Thelma (Wileman) Yeater.
Shirley is survived by: her husband, Frank S. Goss, whom she married on Feb. 26, 1962; her children, Tina Van Horne, Tamie Harling and companion, Rodney Yearick, Carol Platzer and Larry, and Frank S. Goss Jr. and wife, Jeanie, all of Lewistown; three grandchildren; seven great-grandchildren; two great-great-grandchildren; her siblings, Paul Yeater and wife, Patricia, of McAlisterville, Phillip Yeater and companion, Judy, of Mifflintown, and Betty Gordon, of Maryland.
She had worked at Arrow Shirt Factory for 17 years and Scotty's Fashions for 17 years.
Shirley loved spending time with her family and enjoyed taking care of others.
A private service for Shirley will be held at the convenience of her family.
Hoenstine Funeral Home Inc., 75 Logan St., Lewistown is in charge of all arrangements.
Online condolences may be expressed to the family at www.hellerhoenstinefuneralhome.com.


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As it turns out, our four-legged friends love Valentine's Day too. Tap here to see pets in love on u local.
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Hi! My name is Chelsey
I am Domestic Mediumhair from Surfside, SC
Nicknames: Chelsey Cat
Age: 23 years old
Gender: F
Coat: short haired
Education: She butts me in the head to get under covers, she only is about 10 lbs,,It hurts ! lol
My favorite tricks and treats are: no,,she is tooooooooo tired..:( and nothing no treats only SALMON ! hehe
Where I hang out: bed
My favorite grubs: salmon only !
My pet peeves: eats nothing but SALMON
What I love about my owners: She lets me cuddle anytime , anywhere !
My cat hobbies: sleep ...curled up on the bed or in a patch of light..She deserves it, she is 15 yrs old !
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Gov. Walker wants other governors to ride Harleys during Milwaukee visit
National Governor's Association meeting to be held in August
UPDATED 9:23 PM CST Mar 05, 2013
Gov. Scott Walker wants to organize a Harley ride during the National Governor's Association meeting in Milwaukee in August.
The governor made the announcement during a visit to the Harley Museum in Milwaukee on Tuesday.
"It won't be a long ride. Probably from about where the VA grounds are at," Walker said. "We've offered to have them have a riders' ed course at the Harley Davidson dealer closets to their state capitol," Walker added.
Walker said several other governors have already signed up.
The National Governors Association meeting is the first week of August.
Copyright 2012 by WISN.com All rights reserved. This material may not be published, broadcast, rewritten or redistributed.


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Mavericks' DeJuan Blair did not get a warm welcome in San Antonio during Game 2 of the San Antonio Spurs-Dallas Mavericks opening playoff series.
Since Blair parted ways with his former club, he wasn't shy about letting the Spurs know how he really felt.
From letting the Spurs know he felt they didn't believe in him, saying if he had played in the 2014 NBA Finals versus the Heat the Spurs would have won the title to saying the Spurs didn't give him "anything."
Needless to say, these verbal jabs didn't go over well with Spurs fans and when he entered Game 2 in San Antonio, Spurs fans showered him with a cascade of boos. However, it didn't bother the former Spurs big man at all.
"It's pretty cool," said Blair, who was booed when he entered Wednesday's game. "Just the whole environment and the boos and all that was just something that was a lot of fun for me."
Blair finished with eight points, seven rebounds and four steals to help seal the win and steal home court advantage form the Spurs heading into Game 3 in Dallas.
If Blair wanted some measure of payback against his former club, he got it with that performance and he was excited to face his former team.
"This is something that's a dream, to always go against somebody who knows you well, just like you know them," Blair said after Friday's practice. "I'm just excited like everybody else."
When the series shifts back to San Antonio Wednesday night, something tells me Spurs fans will continue to let Blair know how they feel – just like he let the Spurs know how he felt when he joined the Spurs' Texas rival. I am sure they'll be excited too.


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I bought a pair of XLS Drivecore 1000s, very happy with them.
I put both in bridge/mono mode but now I wish to return one of them to factory default setting stereo bypass.
I hold down Mode/Menu button for 3 seconds, get into AMP selection mode, advance to bypass mode but it won't take. The amp always powers up in bridge/mono mode.
XLS DRIVECORE Stuck in Bridge Mode!
Started by mdlowe, Oct 16 2011 09:40 PM
1 reply to this topic
Posted 16 October 2011 - 09:40 PM
Posted 17 October 2011 - 12:04 AM
Well, i finally got the thing back to stereo/bypass mode, no thanks to the instruction manual.
It was a brute force, trial and error effort but everything's fine now.
It was a brute force, trial and error effort but everything's fine now.


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Thank you for visiting our past auction result archives. If you have an item identical (or similar) to this auction lot, please call, write or contact us to discuss. We will be able to help you.
Lot # 1559 (of 1594) < Previous Lot | Next Lot >
1900 T1 Turkish Trophies "Actresses" Complete Set (25)
Starting Bid - $200.00, Sold For - $1,057.50
Catalogued T1 by Jefferson Burdick in the American Card Catalog , this striking premium set issued in 1900 includes twenty-five colorful lithographed cards (8.25 x 6.25 inches) featuring various then very well known actresses dressed in theater costumes, highlighted by such stars as Ethel Barrymore and Lillian Russell. Each card in this set could only be obtained by redeeming the coupons, which were included in packages of Turkish Trophies cigarettes. Bright, clean, and extremely impressive, the set grades Excellent overall (includes a few slightly better). The blank reverse of each card is perfectly clean. This very scarce issue is rarely offered as a complete set. Total 25 cards. Reserve $200. Estimate $400/$600+. SOLD FOR $1,057.50
(Click the smaller thumbnails to the left and right (if any) to cycle through each photo in the gallery of images for this lot.)


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It's been over six years since I stepped into a chemo infusion center. I remember being blown away by the visual: tons of small rooms with curtains along the outside and an inner circle of brown leather recliner chairs in the middle, all occupied by people hooked up to IVs. That scene was a lot to take in six years ago. I thought this time it would be easier...
But I was wrong.
I honestly constructed this idea in my head that I could just continue to take the new chemo in pill form and forgo the IV chemo all together – or maybe do the IV chemo but not lose my hair.
I know people..."it's just hair"... ugh, if I hear that one more time! It's almost humorous to me now. I've even tried that mantra on myself while hoping to suppress my fears. But I'm going to be real: Yes, "it's just hair," but this part of the chemo process is the most visual sign to me – and to others – that I am ill. No more pretending through hot pink and purple hair that I'm fine. Now come the big guns.
I was so nervous for my first IV chemo day (I'm doing the lovely carbo taxol cocktail) that I decided to blow off some steam before my appointment and do a Barry's Bootcamp class. Yeah, that's totally normal, right? Ummm no! I know that sounds bonkers, but since my appointment started at 11 a.m., I wanted a morning distraction and didn't want to get all anxious about chemo, so I figured I would instead push my body hard so that my mind didn't have time to think.
The Big DayI walked into the hospital at 10:55 a.m. and it was funny to me how organized everything was: check in, wait in the waiting room, eat a cracker then get your blood drawn. Pretty simple so far, right?
Now comes the hard part: walk into the infusion center. As soon as I walked through those doors, it hit me like a thick layer of heat ... this infusion center was different than my first one, but just as daunting.
This infusion center is a long skinny hall with patients on either side hooked up to their IVs. I was instantly overwhelmed (note to others if you're anxious like me: look down while walking into the infusion center during your first treatment as it can be a lot to take in the first time you go).
They walked me towards the end of the hall and my doc came in and started talking about the changes they have made to chemo over the past six years: an IV bag for nausea, an IV bag of steroids and an IV bag of Benadryl-type "stuff" to help knock me out while getting the treatment.
I sat and listened while on auto pilot mode ... "Yep, yeah, uh huh, got it." I was trying to hear him while not trying to let my mind drift off to crazy, crazy land. I tilted my head up high so my welling up tears wouldn't stream down. The doctor then paused and the nurse handed me a list of places to get wigs ... And BOOM the welling up tears came streaming down my cheeks.
Embarrassed for crying, I started to apologize. My doctor comforted me with saying, "I only treat women and every woman's first infusion always has them getting emotional. It's partly because of the steroids I put you on, but it's also because this is the start to something you, everyone dreads. Yes, you have done this before but it's okay to be emotional. If you weren't emotional, I would be worried you aren't human." His soft humor made me crack a smile and I took the box of tissues from his hands trying to eliminate any evidence of my weak tearful moment.
"It's just hair," I mumbled to myself, rolling my eyes at my own words. "I'm being so stupid. It's just hair!"
I've tried to think of all options to avoid the hair loss. I'm very Southern and have always thought my best feature is – my hair. I know, it sounds dumb to most, but it's a part of who I am ... and it's part of my best dance move ... the hair flip. :)
People have told me about "ice caps" and other so-called solutions, but my doctor told me it isn't recommend if cancer is in any lymph nodes. So yep, call me a big ol' dramatic baby ... I don't care. I'm pissed off that I have to do this all again. It sucks! There I said it. It sucks, but whatever, I'm doing it and I'm gonna get healthy and kick this cancer crap out of me for good. Then I'm going to grow my hair to my gluteus maximus. Watch out Guinness Book of World Records hair lady I'm coming after you!
A Wave of EmotionMy sister entered my IV infusion room as they started my drip gently placing my "chemo bear" to hide where the IV goes in. I swear that dang bear is the best distraction for needle wimps, especially during a long infusion.
Then it hit me – a wave of emotions. I'm pissed, sad, scared all at once and my thoughts are scrambled everywhere. This is it, the moment I've dreaded. I'm a mess and have zero control of my emotions. It's like the dam done broke y'all. No, it wasn't my finest moment.
I looked into my sister's eyes and felt comfort, especially as she grasped my hand and fidgeted with a butterfly bracelet on my wrist. My mom's symbol was a yellow butterfly, so as Megan fidgeted with my bracelet, I knew it was her way of reminding me that our mom was with us.
I started to get groggy and tried to fight it as I got through texts and work emails, but my mind was getting so fuzzy. The drugs are no joke and act fast. I started to feel my anxiety release and welcomed unconscious land. I swear these new chemo drug combos are great. I was loopy and drifted in and out during the infusion. Weirdly enough, I loved the feeling because time was flying by.
We left the hospital at 8:45 p.m. and I felt like I had slept for days. On the way home I kept apologizing to my sister for having to be at the hospital for so long. She rolled her eyes in annoyance and said, "I'm coming to every one of them you idiot."
Sisters have a great way of being blunt, yet making you feel comforted through brutal honesty when you are acting crazy.
So now it's the waiting game: 10 days until my hair starts falling out and two weeks until I rock the "Mr. Clean" look. I know "it's just hair," but this is the part I'm dreading as I've loved walking around N.Y.C. as though everything's fine.
Last time I felt like I was "hiding" when wearing a wig, but then felt like eyeballs were on me when I didn't. I'm trying not to focus on it, but it's how I feel, it's part of the cancer treatment process that you can't ignore.
"It's just hair" ... hair today, gone tomorrow and I pray that with the hair loss, my cancer will lose too.
Check back for updates every Thursday: Diem will be chronicling her journey through fertility treatments, chemotherapy, and her quest to educate others about ovarian health exclusively for PEOPLE.com. You can also follow her on Twitter @DiemBrown


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July 26, 1999
Wine with Fechin, by Patricia Raab.
Bothell's Framewright Galley is hosting a month-long exhibit by a dozen local artists who humorously call themselves the "Northshore 12."
The name is a take-off on a group of Russian artists from St. Petersburg's Hermitage Group who have been touring the U.S. since the fall of the Iron Curtain and who recently conducted workshops at Seattle's Frye Museum.
The exhibit, "To Russia With Love," is a tribute to Russian Impressionism and a celebration by the Northshore 12 of eight years of study under regional artist Patricia Raab, who teaches at the Arts Umbrella in downtown Bothell.
Artists exhibiting in the show include Patricia Raab, Jamie Bartalamay, Lynda Buchanan, Judith Erickson, Mary Ann Germann, Terry Moos, Lucille Peterson, Roni Uyeda, Chris Witzke, Brian Cole, Brad Peterson, and Ted Pankowski. The exhibit opens July 30 with an artists' reception from 5 to 8 p.m. at Framewright Gallery, located at 18104 102nd Ave. NE in downtown Bothell.
"To Russia With Love" will run through Sept. 7. For further information, contact Lynn Asmann at 425-483-7385.


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Fifty years ago, Williamsport Technical Institute installed its first computer on the campus that is now Pennsylvania College of Technology, pioneering the early development of computer science education.
The first computer had its own small room, which could accommodate about 10 students at a time gaining hands-on experience in the college's first "data-processing" courses. What grew from those courses is a highly equipped campus that hosts five information technology majors and one computer for every three students.
The impetus for bringing computer education to Williamsport Technical Institute - as the institution was called from 1941 to 1965 - came from a $125,000 National Defense Education Act grant that enabled the college to receive a state-of-the-art computer system. In return, the grant obligated WTI to design a two-year computer-programming curriculum and teach a pilot class, then share its findings with other schools interested in initiating a similar program.
The grant was the result of increased government spending on aerospace endeavors and technical and scientific education after the Soviet Union launched Sputnik 1, the world's first artificial satellite, in 1957. The launch ushered in the Space Age, along with a fear among U.S. officials that there may be a technological gap between the two nations.
George P. Wolfe, a young mathematics instructor who, with one Fortran programming course in graduate school was WTI's most computer-savvy faculty member, was tasked with developing the curriculum and teaching its first courses.
As Wolfe studied and sought industry expertise, WTI staff selected a classroom in the southwest corner of Unit 6, a former trolley-car depot that had become classroom and office space for the institute. The site, now occupied by a parking lot and Remembrance Garden, is on Third Street, east of today's Carl Building Technologies Center.
The Unit 6 classroom was expanded and remodeled to include a lecture area and the adjacent laboratory, which housed the data-processing equipment and punch-card storage. It featured a raised floor to absorb the computer's vibrations.
In October 1963, with lab space and curriculum ready, one instructor and 24 students inaugurated the first computer technology class in the college's history. Two years later, as WTI became Williamsport Area Community College, 17 of the first 24 students graduated from the major, then called "engineering and design data processing technology," and each quickly found work in the emerging field. The same year, the program changed its name to "engineering computer science technology," and a second major was added in "business computer science technology."
1965 also marked the beginning of automated records processing with the formation of the administrative data processing department. William Heverly, who had been hired a year earlier to split his time between teaching and exploring such a department, was assigned to the initiative full time.
In 1966, the college took part in a Penn State experiment in distance learning, serving as a remote site for the university's trial of what was then called "computer aided instruction." Two teaching stations were installed in Unit 6, consisting of a two-way typewriter, slide projector and audiotape player, all interfaced via a direct phone line to the mainframe on Penn State's campus. Selected computer science students served as lab assistants and experiment subjects.
In 1967, as the program grew, it moved to the Rishel Building, a former furniture plant (after the company moved its operations to the facility that is now Penn College's College Avenue Labs building). Taking advantage of its newfound space, the college acquired its second and third computer systems: an IBM 1401 and a Univac Spectra 70. The COBOL programming language was taught for the first time.
In 1972, Bill Ward, who had been a member of the college's computer science faculty, was appointed director of administrative data processing.
Eventually, computer use expanded to many of the college's academic majors, and in 1984, Wolfe was appointed director of a new Academic Computing Division, which supported computer instruction campuswide. He remained in the position until 1989, when he became the first director of the college's Technology Transfer Center, the predecessor of today's Workforce Development and Continuing Education. He was replaced by Jim Cunningham, '96, who would eventually become the college's vice president for information technology and business process improvement before retiring in 2012.
In 1985, Mike M. Cunningham, '75, was named manager of systems and programming. He eventually became the director of administrative data processing and later the chief information officer. Today, he is the college's vice president for information technology and CIO. Jim and Mike are among seven Cunningham siblings to graduate from Penn College and WACC.
In 1992, the college opened its first personal-computer lab on the second floor of the Breuder Advanced Technology and Health Sciences Center.
"The early IBM PC/STs were equipped with a 5 1/4-inch floppy disk drive, a 20 MB hard drive, small green-screen monitor and a whopping 640K of memory," Jim Cunningham said. "Compare that to a typical PC of today: DVD drive, 500 MB hard drive, 19-inch HD-resolution color monitor and 8,000K of memory."
The college's first computer network was installed in 1993. In 1994, email came to the college. It was used only internally until 1995, when the college made its first Internet connection.
"Today, email is something people take for granted as a way to communicate between different companies, but some of the first nonresearch use of email was within a company, employee-to-employee," Mike Cunningham explained.
With the campus connected to the Internet, the college launched its website, www.pct.edu. Today, the award-winning site provides information on admissions and academic majors, video clips and photographic features, a virtual tour of the campus and access to college news through PCToday, which is updated throughout the day.
In the late 1990s, the Academic Computing and Administrative Computing divisions merged to form today's information technology services.
In 1996, students, for the first time, scheduled their classes online.
"Prior to online scheduling, students had to report to the Registrar's Office at their allotted time with their desired schedule of classes written on paper," Mike Cunningham said. Students used a printed master schedule to look for the classes they wanted to take.
"The registrar had three terminals to the mainframe where they could enter in the student's schedule. Any classes that did not have room left would be rejected and the student sent away to find a different class and return to the registrar," he said. "Some students had to make many trips, and the entire process could possibly take days. Lucky students got all their classes on the first try and were only in line for a few hours."
In 1997, the college installed networks in residence halls, and in 1998, the Student Information System, which allows students to access their records online, was launched. A similar system for faculty and staff, the Employee Information System, was launched in 2005.
The college implemented a learning management system in 2001, providing the first platform for faculty to interact with students online. Today, among its many functions, faculty can provide video, lecture notes and chats, while students can submit homework, take exams or complete entire courses online.
In 2005, a high-speed wide-area network was installed to link the college's five locations (the North Campus in Wellsboro, the Advanced Automotive Technology Center on Wahoo Drive, the Lumley Aviation Center in Montoursville and the Schneebeli Earth Science Center near Allenwood).
In 2007, the college implemented the myPCT Portal, an intranet for internal information sharing.
By 2009, the college's wireless network encompassed all parts of campus, and 100 percent of classrooms and labs were technology equipped.
In October, the college hosted a daylong Golden Anniversary celebration for information technology majors. Eight alumni offered talks for current students. The speakers' careers span from top-level information and networking security positions, to systems engineers and systems administrators for hospitals, universities and such companies as Penn National Insurance, Learning Sciences International, Cisco Systems, Lockheed Martin and Dell. Alumni presentations were followed by campus tours and a reception and talk with Wolfe.


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Sir.—I am writing in reference to the article by Raunikar and Sabio1 in the October 1992 issue of AJDC. I commend the authors on compiling an excellent case for attending to the iron status of adolescent athletes. However, there are a few points on which I differ from the authors.
First, there are better criteria for judging anemia in adolescents than those used by Raunikar and Sabio.1 I refer them to the articles by Daniel2 and by Liebman et al,3 in particular. The racial differences in norms for hemoglobin levels and hematocrit should not be disregarded. Second, a study I was involved in showed significant differences on measures of iron stores between athletes and nonathletes.4 Third, adolescents do not necessarily have poor dietary nutrient intakes compared with adults. As the authors pointed out, however, adolescent girls, both athletes and nonathletes, consume significantly less iron than
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A Randomized Trial of an Antibiotic- and Antiseptic-Coated Central Venous Catheter in the Prevention of Catheter-Related Infections—Reply
Tennenberg SD.
Arch Surg. 1998;133(9):1022-1022.
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Tuesday 13 May
8:15 Morning Coffee
Sequencing of Cell-Free DNA (NIPT Continued)
8:45 Chair's Remarks
Brigitte Faas, Ph.D., Department of Human Genetics, Radboud University Nijmegen Medical Center (Netherlands)
8:50 Non-Invasive Detection of Chromosomal CNV and Single Gene Disease
Ya Gao, Ph.D., Senior Application Specialist, NIPT, BGI
Cell-free DNA based prenatal testing has been shown with close-to-diagnosis sensitivity and specificity in detecting fetal T21, T18, and T13. Future development of this technology focuses on detection of other chromosomal aneuploidy, and more importantly submicrosocopic abnormalities such as small copy number variants and single gene mutations. We evaluate the possibility of testing CNV in samples with known karyotypes by NIPT using FCAPS analysis and successfully identified the deletion and duplication on difference chromosomes. We also developed a haplotype construction strategy to non-invasively identify the fetal risk of a single gene disease, which has the clinical potential for non-invasive prenatal diagnosis of single gene disease.
Sponsored by
9:05 Contingent cfDNA Screening with Additional Serum Markers - A Highly Cost-Effective Strategy
Howard Cuckle, Ph.D., Department of OB/GYN, Columbia University Medical Center (USA)
Routine screening for Down syndrome using maternal plasma cfDNA alone is too expensive for public health programs. In contrast, the contingent use of traditional protocols such as the Combined test to select 10-20% women with the highest risk for cfDNA is cost-effective. Enhancing the Combined test with the addition of serum PlGF and AFP yields contingent cfDNA detection rates close to routine cfDNA. This approach also facilitates early screening for adverse pregnancy outcomes like pre-eclampsia.
9:35 Development of NIPD for Detection of Single-Gene Disorders within an NHS Regional Genetics Service Laboratory
Fiona McKay, Principal Clinical Scientist, NE Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Foundation Trust (United Kingdom)
It is now possible to base the diagnosis of an increasing numbers of monogenic disorders on the analysis of cfDNA in maternal plasma. Our laboratory has developed significant experience in this area having implemented fetal sex determination as well as leading the RAPID project - funded to develop standards required for implementation into NHS practice. Service and research teams work closely to facilitate rapid translation into clinical practice, and we now offer a UKGTN approved service for fetal sex determination, achondroplasia and thanatophoric dysplasia. Here we discuss the development of our NIPD service and the introduction of next generation DNA sequencing methodologies to improve workflows, shorten turnaround times and increase the breadth of testing for monogenic disorders.
10:05 Epigenetic Strategies for NIPD: The Power of the Fetal Methylome
Elisavet A. Papageorgiou, Ph.D., CSO, NIPD Genetics, Inc. (Cyprus)
The evaluation of identified DMRs (Differentially Methylated Regions) will be presented, with the aim of developing NIPD for fetal chromosomal aneuploidies. A comparison analysis will also be reported describing the performance of different assays, indicating the potential use of different methylation-based technologies in retrieving the fetal methylome towards NIPD.
10:35 Coffee Break in the Exhibit Hall with Poster Viewing
11:15 Panel Discussion: Sequencing-Based Diagnostics of Cell-Free DNA in Maternal BloodModerator:
Phillips Kuhl, President, Cambridge Healthtech Institute
Panelists:Thomas Musci, M.D., CMO, Ariosa Diagnostics, Inc.
Michael Lutz, Ph.D., CEO, LifeCodexx
Solomon Moshkevich, Vice President, Marketing and Medical Education, Natera Inc.
George Koumbaris, Ph.D., Head, Research and Development, NIPD Genetics Ltd.
Mathias Ehrich, Ph.D. Vice President, Research & Development, Sequenom, Inc.
Vance Vanier, M.D., Vice President, Global Commercial Operations, Verinata Health, Inc.
In the field of prenatal molecular diagnostics, no technology has had more extensive and rapid impact than sequencing of cell-free DNA from maternal blood. A number of companies have commercialized this approach, which provides a non-invasive method for identifying cases of aneuploidy with very low false-positives and false negatives. There are key differences between some of the techniques being implemented, differences in business strategies and a range of issues for which opinions and options vary. This panel provides a unique opportunity to hear from six different commercial vendors speak briefly about the approach their company has taken, and then respond to questions.
Some of the issues to be covered will include:
Additional questions can be submitted, and may be posed by the panel moderator. Please click here to suggest additional questions for this panel.
13:00 Luncheon Presentation (Sponsorship Opportunity Available) or Lunch on Your Own
Isolation and Analysis of Fetal Cells From Maternal Blood
14:30 Chair's Remarks
Patrizia Paterlini-Brechot, M.D., Ph.D., Professor, Cell Biology & Oncology, University Paris Descartes (France)
14:35 Analysis of Trophoblastic Cells for Non-Invasive Prenatal Diagnosis of Genetic Diseases
Trophoblastic cells can be isolated non-invasively from blood and from the cervix at very early terms of pregnancy. Their fetal DNA is not mixed with maternal DNA and can be efficiently used for prenatal genetic diagnosis. The use of fetal cells allows the development of a reliable non-invasive alternative to the current invasive methods for prenatal diagnosis of genetic disorders.
15:05 Isolation and Verification of Circulating 4B9-Positive Fetal Cells from Maternal Blood
Leonard Kellner, President, KellBenx, Inc. (USA)
Identification of circulating fetal cells in maternal blood would enable noninvasive prenatal analysis of the entire fetal genome. The discovery and characterization of a novel fetal erythroid cell marker, 4B9, will be described. Results demonstrating frequency, isolation and verification of 4B9 positive fetal cells from maternal blood will be presented.
15:35 Isolation and Characterization of Individual Circulating Fetal Cells for Non-Invasive Prenatal Diagnosis
Nicolò Manaresi, Ph.D., Chief Technology Officer, Silicon Biosystems spa (Italy)
We present DEPArray™, a fluorescent image-based sorting platform and its potential for the isolation with single-cell resolution of fetal cells enriched from maternal blood samples. In combination with Ampli1™ Whole Genome Amplification, we show that it is possible to confirm fetal origin by DNA fingerprinting, carry out array Comparative Genomic Hybridization as well as analysis of point mutations. The above capabilities can be the cornerstone for enabling 1) the set-up and validation of a dependable enrichment and staining method and 2) further bring this workflow into a routine clinical practice.
16:05 Refreshment Break in the Exhibit Hall with Poster Viewing
17:00 Panel Discussion: The Future Landscape of Prenatal Molecular Diagnostics in Europe
Michael Hadjidaniel, Ph.D., Acting Head of the Translational Genetics Team, Cyprus Institute of Neurology and Genetics (Cyprus)
Marta Rodríguez de Alba, Ph.D., Genetics Department, Fundacion Jimenez Diaz (Spain)
18:00 End of Conference
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Just recently I was having a conversation with someone I know who is studying to become a doctors assistant and we were discussing something she had learned that day, I would like to share what she told me so that maybe it will help some readers who are trying to deal with insurance companies during Stage 4 cancer.
In the insurance class students are being taught that when someone with Stage 4 cancer files a claim it will immediately be rejected. If the person with Stage 4 cancer wants their insurance to cover them they must produce documents and for a second time submit their claim, only to be denied insurance coverage for a second time. In order to file a claim again they need to jump through more hoops. It is after the third time the Stage 4 cancer patient submits their file will they be approved.
To make matters more complicated, the Stage 4 cancer patient needs to get their third file in for insurance coverage in within three months!
I was appalled to learn of this practice. I can only imagine what it must be like to have Stage 4 cancer and to be treated by the insurance companies, or anyone for that matter, in such a way. I don't believe it's ethical, necessary, or right.
Thought you would like to know about this fact, it might be helpful during a challenging time. Many blessings to you all and may you never have to go through this horrible experience.


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The battle between traditional marriage and gay marriage is heating up in Rhode Island.
Vermont Gov. Peter Shumlin visited the Ocean State last week to support the legislative efforts toward gay marriage. As a state senator, Shumlin worked to legalize gay marriage in Vermont in 2009. Shumlin, a Democrat, was elected governor last fall.
Vermont lawmakers authorized civil unions 10 years ago. Shumlin urged Rhode Island to avoid that "half step" and pass a full gay marriage law instead.
"We went halfway, and halfway on civil rights isn't good enough," he said during a joint news conference with Rhode Island Gov. Lincoln Chafee on Thursday.
Chafee, an independent and a long standing supporter of gay marriage, says if a measure is approved by the state legislature, he'll sign it.
A Rhode Island General Assembly committee has held hearings on the bill but has not yet voted to send it to the full House or Senate.
Chris Plante, director of the Rhode Island Chapter of the National Organization for Marriage, said he's optimistic the bill may stay bottled up in committee and never make it to a General Assembly vote.
Five states in the U.S., plus the District of Columbia allow same sex marriage. Supporters of traditional marriage recently shut down a push for same-sex marriage in Maryland.
Gay Marriage Stays on Hold in California
Gay Marriage Bill Defeated in Maryland
GOP to Push to Overturn DC Gay Marriage Law
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Are you seeking answers in life? Are you hurting? Are you facing a difficult situation?
Find peace with God, discover more about God or send us your prayer request.
Call The 700 Club Prayer Center at 1 (800) 823-6053, 24 hours a day.
A caring friend will be there to pray with you in your time of need.
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This Insane List of Demands Is Why Women Feel They Have to Be PerfectCarolyn Castiglia
There is still a subtle insinuation in our society, no matter how far we've progressed, that women have to be perfect in order to be desirable. Sure, many women are able to get past the idea of trying to be "desirable" period, reminding themselves that women don't exist for the pleasure of men and yada yada yada. But the truth is, men are visual creatures, and we are all being judged – men and women alike – by prospective dates. Precisely because we know so many men still are looking for that perfect female specimen to fulfill their every desire, it's easy to forget that you don't have to be a "perfect" person in order to find the perfect person for you. Remember, not every guy is a shallow, narcissistic jerk. And the ones who are should not be taken seriously! Like this guy, a successful surgeon who sent out an email to all of his networking contacts with the following list of things he's looking for in a woman:
- Age 27-35 (ideally 28-34)
- No kids, wants kids in the next 1-2 years
- College graduate, doesn't have to be a great school, but needs to have finished the degree
- Skinny (i.e. dress size 0-2, if you don't know what that means (many men don't) it means very skinny)
- Caucasian (not black, not Hispanic, not Asian)
- Healthy lifestyle (defined as no smoking, no drugs, good diet, no hard drinking)
Ah, the perfect skinny white girl! What I grew up wanting to be! Feeling like I should be, in fact. It wasn't until I moved to a black neighborhood in New York City and discovered that the men there liked that I wasn't skinny that I stopped feeling like I had to be someone else to be attractive. And it wasn't until very recently that I realized that I don't want to date anyone who is going to objectify my body in any way at all! Since that's a super tall order, guess who's not currently dating??? (Me.) I'm just tired of feeling like men look at me body first, soul second, if they're getting to that second part at all.
The "perfect female specimen" means different things to different people, but nonetheless, objectifying women – or men – isn't going to lead anyone to true love. The idea that certain physical and emotional qualities are what make a person perfect and that only those qualities will work for you is limiting for everyone involved. If you're looking for a person with very strict qualities, you're cutting yourself off from the possibility of being surprised by someone who's not your "type," and if you're trying to *be* someone that fits a list of "perfect" criteria, you're wearing yourself out for no reason and preventing yourself from expressing the fullness of your self.
As for the surgeon looking for the perfect woman – his list of demands doesn't stop there. Oh no, it's much longer, in fact. He also wants her to be submissive (OF COURSE) but successful at work (RIGHT), nice (NOT BITCHY AND SELF-ABSORBED LIKE HIM) and come from a healthy family (HA!). If you want to see the whole thing, go read it and weep/laugh over at YourTango.
Image: iStock/PicMonkey


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The state of Iowa is one of the richest states in the country in terms of native history, but also in terms of natural attractions, cultural events and festivals.
One option is the Chase Suite Hotel Des Moines, located in 11428 Forest Avenue, really close to some of the city's most important and interesting places. If you stay there you will be able to enjoy a full continental breakfast service, evening social hours on some weekdays for you to enjoy the on site bar and have a romantic dinner, a pool and spa, plus a complete fitness center, free parking and a helpful grocery shopping service that will allow you to forget about such things and give in to romance. Hotel suites feature full kitchens, separate living and dining rooms, luxurious beds and cable TV. Rates start at 110 dollars.
Another option to take into account for a romantic honeymoon is the Quality Inn and Suites Event Center. This hotel is located in 929 3rd Street close to Des Moines downtown. It features a continental breakfast and a private restaurant, room service for you to ask all the meals you want and enjoy them together in your suite, a pool and spa, an exercise room and a comfortable cocktail lounge for romantic moments. The suites include air conditioning, private appliances, internet access and cable TV. Prices for them are around 90 dollars a night.
In Des Moines you can also find the Holiday Inn Hotel and Suites Northwest, which is located in 4800 Merle Hay Road. You can enjoy the on-site restaurant and pub that serve three meals a day, plus room service, a swimming pool and exercise center as well as a game room in case you want to enjoy entertainment together. This hotel also offers you recreational near by areas for practicing sports and to enjoy sunny days. Suites include private appliances, truly comfortable furniture, TV and telephone and prices for them start at 110 dollars.
Cabañas en Iguazu


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February 1, 2013
Is Clean Energy an Impossible Dream?
Taylor & Van Doren, Huffington Post
Don't get us wrong: If low-polluting renewable energy sources could displace fossil fuels without massive taxpayer subsidies that would harm the economy, you'd find us at the front of the parade. But President Obama's undying devotion to clean energy -- memorably invoked in his inaugural address -- should trouble anyone who does not believe in showering public money on industries with no hope of a back-end payoff for the taxpayer or consumer. . .
TAGGED: U.S. Energy Policy, Clean Energy, Huffington Post


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While upcoming PC and DS title Spore is an interesting game, it's difficult to pin down exactly why. A combination of five different game genres, including arcade, MMO and RTS, it's also a platform for users to create monsters, vehicles and buildings and share them with other players across the world. Confused? We sat down with the game's gameplay producer Thomas Vu to ask him to lift the lid on what promises to be one of the PC's top titles in 2008.
VideoGamer.com: Is Spore a hard sell?
Thomas Vu: I don't know if it's a hard sell? I would say it's a hard thing to do or understand and grasp, because it's massive in scope, it's very high concept, it has lots of new ideas. It's not something we can say it's like Half Life 2 or it's like StarCraft, we can't really say that because there's nothing really to latch on to. Often times new is really cool but new is really hard to explain. It is a hard sell but I like the challenge. I came on this project wanting to have this challenge. It's a huge challenge but the reward could be awesome.
VideoGamer.com: You've worked on The Sims 2, right, so you know that audience well?
TV: We try our best to do Spore in a way that will appeal to that audience but at the same time we understand that Spore is a different beast altogether. Sim City was different to The Sims and Spore is going to be different than The Sims. What we are building is based on creativity, sandbox gameplay, create what you want and watch it happen in the game, and then we have the sharing of content. On all of those fronts we've gone beyond what we've seen. The concepts are different but the underlying basis is still you're making this toy, this sandbox.
VideoGamer.com: Is there any pressure to deliver a hit in the same way The Sims was?
TV: There's always pressure. For me, ultimately, it's about am I making a game that I can be proud of. Is it a game I could play? For a lot of these guys, for EA and marketing, they're obviously, the more you sell the better! But for developers, us, we love to sell a lot, that's great, because it's popular, but at the same time we want to make sure we're proud of the game we make, we push the industry forward, we have other goals that are not just monetary.
VideoGamer.com: You've mentioned that Spore will be a franchise. Does it need to do a certain amount for that to happen or will it happen anyway?
TV: The reason why we think that way is because the way Spore is set up makes it very easy for us to add new things. The onus is on the player now, on the user making content. We pretty much gave up so much power. For us the concept of Spore is, it could be anything. It's so wide. I mean making life is so wide. Creatures can go in any which way, tribes can go in any which way, civilisation, space, anything you can imagine. All the history of ideas that we've had up to this point, we can say, OK, make it like this or make it like this, so that itself has enabled us to feel like, if Spore's a huge hit, if it's a platform for other things, we open ourselves up to this whole possibility of going crazy anywhere. At the same time that's awesome responsibility. But we have to make sure that we're making the right things, spending our time on the right things. The team is 80 people. It's not big by any standards for a game of this size, so we have to be careful about what we're spending our time on.
VideoGamer.com: The game has been confirmed for the DS. Why not Wii, PS3 and Xbox 360?
TV: We are looking into them. We are always open to figuring out how Spore as a platform, where it can go. Because the game is deep we're really just concentrated on the PC version. We want to make sure that's solid. For the other platforms, we're in the process of looking at tech specifications, how would pollination work on Wii and 360, how do you play RTS on a console, is it adequate, does it flow right? So there's lots of questions like that, all answerable, it's just time and how much we can throw at it and still get our PC version out cleanly.
VideoGamer.com: But it's certainly possible?
TV: It's certainly possible. Like anything, the base for Spore is huge. It can go very casual web game, it can go any of these places. But we have to be sure where to spend our resources.
VideoGamer.com: As you work your way through the game you see more traditional game elements, like RTS dragging over units that sort of thing.
TV: That's one of the biggest challenges we had making the game. It's funny because Spore goes from very light to almost hardcore. Very few casual players play RTS games. The controls are harder, you have to use the keyboard. In some ways, as life gets more complicated, the game gets more complicated.
VideoGamer.com: If controls are one of the things holding back the console versions of Spore, the Wii Remote seems to be almost as close as you can get to a mouse. Would the Wii be a more likely platform?
TV: It would definitely be something we would look at as a possibility, with the Wii being very popular. Ultimately it ends up on, what's the audience? Even with the DS, it skus younger, 12 to 19 [year olds], so the gameplay is a little different. As long as we can hold on to the spirit of Spore and the concept behind what makes Spore really cool in the consoles I don't see a reason why we can't. It ends up being, do we have enough people to do it and where do we want to focus?
VideoGamer.com: It seems like the Wii audience would be a perfect fit for Spore.
TV: The audience that we're going for is pretty broad. We know we're setting up the tools for creators - for the creators, some might not even play the game, they just want to create for other players and share them. For the gamers, who, maybe want to do creation but not as much as the creators, they want to play the game and they want to see the cool content, and then there's another audience that we call the explorers, and those are the people who don't want to go hardcore into the game, they just want to float around the game like a sandbox and look at other people's content. So the audience for Spore hopefully is very broad and diverse. Any of the audience that you find on the Wii, Xbox or PS3 would be the sort of audience we would go after.


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UN Secretary-General's Climate Change Support Team Chief Holds Press Conference
4 December 2009: During a press conference held at UN Headquarters in New York, US, Janos Pasztor, Director of the Secretary-General's Climate Change Support Team, underlined that there were several signs of optimism that the outcome of the UN Conference on Climate Change in Copenhagen would be successful.
In particular, he highlighted: US President Barack Obama's announcement of the US emissions reduction target; the announcements from India and China regarding their efforts to reduce their emissions through energy intensity; the announcement of plans to lower carbon emissions by Brazil, Indonesia, Republic of Korea, South Africa and Mexico, among others; and the Port of Spain Declaration adopted at the conclusion of the Commonwealth Summit, in which 52 Heads of State and government indicate they were approaching Copenhagen with ambition, optimism and determination. He listed the key elements of an ambitious agreement that negotiators in Copenhagen would focus on, and stressed that by triggering fast-track funding - or the US$10 billion "Copenhagen launch fund" - a Copenhagen agreement would have an immediate effect on the implementation of those issues. He also responded to questions on: the importance of cap and trade in the future Copenhagen agreement; targets and emissions reductions pledges made to date; the validity of criticisms that agriculture had not been adequately included in the Copenhagen negotiations; the involvement of the private sector and certain corporations, such as the Gulf PetroChemicals Industry Company, which claimed to be an official partner of the Conference; the prospects for a financing scheme from the private sector in the agenda; comments by James Hansen, of the NASA Goddard Institute for Space Studies, including that a carbon tax was the only effective way to curb emissions; the question of the hacked e-mail accounts from a British climate research unit; and comments by Ethiopian Prime Minister Meles Zenawi that he had little confidence the developed countries would deliver in Copenhagen. [UN Press Release]


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Ask the Expert: Your Questions Answered -- Updated!
CafeMom is excited to announce that Dr. Eli Meltzer answered your questions about children's allergies.
Dr. Meltzer is Clinical Professor of Pediatrics at the University of California, San Diego and is also a founder of the Allergy/Immunology Fellowship Training Program at UCSD. He is a Fellow of the American Academy of Allergy, Asthma and Immunology, the American College of Allergy, Asthma and Immunology, and the American Academy of Pediatrics.
Check out the questions and answers below!
lalasmama2007 asked: Can seasonal allergies cause extreme headaches?
Dr. Meltzer answered: People most often associate allergies with nose and eye symptoms, not with headaches. However, the respiratory inflammatory response releases chemicals and attracts cells that can irritate nerves, cause swelling and produce headaches. These headaches cause a feeling of pain (not usually severe) and pressure in the head and face above the nose and between the eyes. An anti-inflammatory and/or a decongestant allergy medication and/or ibuprofen may be helpful with such headaches.
Bmat asked: Can seasonal allergies cause sinuses to be clogged so that the child's face aches?
Dr. Meltzer answered: Depending on the severity of the child's seasonal allergies, it is not uncommon that nasal and sinus membranes can become so inflamed and swollen that they cause facial aches. Furthermore, allergic reactions to substances like airborne pollens, dust, animal dander and molds, can lead to obstruction of the sinuses' drainage. Antihistamines and decongestants, such as Allegra and Allegra-D (for children 12 years of age and older), can help keep nasal and sinuses clearer, thereby minimizing the pain that is causing the facial aches.
Xandersmom asked: My son often sneezes a lot. I've had him tested for allergies and nothing showed up. Also, how do I get him to blow his nose? It seems like his least favorite thing to do...well, that and not eat his broccoli! Thanks!
Dr. Meltzer answered: Sneezing is a common way the body clears nasal passages. Many parents have the same trouble with getting their children to blow their nose since some children tend to dislike it. Blowing out - either through the mouth or the nose - is actually a learned behavior so I would recommend practicing this process with bubbles or pretend birthday candles. Once the idea of blowing out through the mouth is established, you can move on to nose blowing out into tissues. It may help to have them gently close off one nostril and blow out through just one side at a time.
Kmakksmom asked: When is a good time for adults and children to get tested for allergies?
Dr. Meltzer answered: A child can be tested for allergies at any age. However, when to do so depends on many considerations, such as the specific symptoms, the severity of the symptoms, what the doctor sees during an exam, and whether or not asthma or nasal allergies run in the family. If you have concerns, talk to your child's doctor and decide together whether or not your child should be tested for allergies. As for adults, moving to a new location or getting a new pet is often a trigger for allergies particularly if you didn't suffer before, so talk to your doctor if you think you may have developed an allergy. A simple rule of thumb is: if the symptoms are compromising the child's or adult's daytime or nighttime quality of life, it is time to evaluate and treat.
pipsmommy asked: Could my 6 month old have seasonal allergies? I have them terribly and my dd seems to get cold about the same time my allergies get bad. She gets sicker than me though, and her symptoms last longer.
Dr. Meltzer answered: It is possible, but unlikely, that your six month old could have seasonal allergies. The tendency to develop allergies is often hereditary, which means it can be passed down from generation to generation. In general, although infants can develop other allergic problems, we are unlikely to notice seasonal pollen triggered allergies earlier than 12 to 15 months. If you suspect your child has allergies, talk to your pediatrician.
Amonkeymom asked: Is there any way to get rid of the "allergy eye" look? All 3 of my kids, as well as myself, deal with this issue and no amount of sleep, allergy medication or makeup ever makes it go away. What do you recommend?
Dr. Meltzer answered: Allergies can cause puffy, red eyes. These are due to congestion and rubbing from the sensation of itch. Treatments include: reducing exposure to allergens such as pollen, dust mites (allergen-resistant coverings on mattresses, pillows and box springs) and animal dander, placing a cold compress on the eyelids for several minutes, and taking an over-the-counter antihistamine, such as Allegra or Children's Allegra. Additional tips include: making sure you stay hydrated with enough water, lowering your salt intake, and sleeping with the head slightly elevated so your respiratory tissues can drain.
jesusgirl76 asked: My daughter is 19 months old. Is that too early for an allergy test?
Dr. Meltzer answered: It is a common misconception that children need to be a certain age before they can be skin tested for allergies. Generally speaking, skin testing can be performed even in infancy and as young as one month of age. It's important to note that the skin of very young children may not be as reactive as older children and adults, and therefore the results need to be interpreted more carefully. An allergy test at such a young age is usually prompted by significant symptoms or that allergic disease runs in the family.
slw123 asked: What can we do about eye allergies? If my son spends any time outside while we are doing yard work, mowing, weeding, etc. His eyes get all puffy, watery and scratchy. What can we do for him to prevent this?
Dr. Meltzer answered: Itchy, watery and puffy eyes are uncomfortable allergy symptoms. Fortunately, there are ways to help combat these problems. One hour before starting the outdoor project, have your children take an effective allergy medication, such as Children's Allegra. When doing yard work, try to keep hands away from the face to avoid eye and nose contact. When finished pruning, planting and potting, don't bring gardening tools indoors and quickly change into clean clothing. Showering and hair washing following a gardening session can also help reduce symptoms.
batjmom asked: The pollen is a big issue at the field where my kids play baseball. What can I give them that will help the itch watery eyes that will not make theme tired? Thank you for your time.
Dr. Meltzer answered: An important recommendation would be to try and prevent the symptoms before they start. I often recommend Children's Allegra an hour prior to going to the field. This antihistamine can block the onset of symptoms from the pollen exposure and provides effective, non-drowsy, 12-hour relief in formulas that are safe for children 2 years of age and older. Also make sure to rinse off their equipment and keep the gear outside to prevent pollen from causing symptoms in the house.
MamaMandee asked: My hubby has really bad seasonal allergies but I don't, what are the chances of my kids having the same issues as my hubby?
Dr. Meltzer answered: An important contributor to the tendency to develop allergies is hereditary, or, in other words, what tends to run in families. However, it is hard to put a number or percentage behind the likelihood of your children developing seasonal allergies because the specific trigger of the allergy reaction is not hereditary. Heredity does not control which of the allergens will affect an individual, only that the system has a low tolerance to allergens. If you notice any of the typical allergy symptoms in your children such as itchy nose, eyes, ears or throat, sneezing, runny nose, nasal congestion or pressure, it is time to visit a doctor to determine if they may have allergies, which specific allergens are causing the reactions, and the best ways to relieve the symptoms.


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you could try taking the offending bits to a computer shop to get them identified.
FCC identification number might help as well.
Try non plug+play detection.
I have a sound card (working) that took me 4 hours to install cus it is so old that it is not PnP compat'
Hope that helps


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Imprint founded by Miami rapper Rick Ross
Warner Bros. Records has entered a partnership with Maybach Music Group, the imprint founded by top rapper Rick Ross.
Maybach's artists include rappers Wale, Triple-C and Meek Mill, who will now join the Warner Bros. roster.
Label chief Ross remains signed to Def Jam as a solo artist. He has released three consecutive No. 1 albums: "Port of Miami" (2006), "Trilla" (2008) and "Deeper Than Rap" (2009); his most recent set, "Teflon Don," was issued last year.
Warner Bros. co-president/CEO Todd Moscowitz said in a statement: "We are thrilled to be in business with Rick Ross. We were drawn to his hustle. Ross is an entrepreneur who built his company from the ground up. He's a music magnate, a lightning rod and an empire builder."


text: Home » Posts Tagged "fresh traveler" fresh traveler Fresh Traveler's Secret to Happiness – HAVE FUN WITH LIFE! Rand McNally 07/21/2012 Comments off We had a lot of fun on this road trip and we are thankful to be a part of something so life... Read More Fresh Traveler's Honda Leap List Rand McNally 07/19/2012 1 Comment To us, "settling down" is settling our ashes down in our grave. A leap list is our list of things that we... Read More How I made my Fourth of July dress from a towel Rand McNally 07/14/2012 4 Comments by Patricia Serrano Sooo… I didn't have a patriotic dress to wear for the Fourth of July so here's how I made... Read More Fun Signage in Denton, TX Rand McNally 07/14/2012 1 Comment The folks in Denton, TX are so hardcore about their fun that they made signs to remind themselves and everyone around them... Read More Fresh Traveler on Buena Park, CA Rand McNally 07/13/2012 2 Comments Buena Park is where dreams come true. Everyone is happy in Buena Park. Maybe it's the constant sunshine. Maybe it's because Snoopy... Read More When it's hailing on you in Arizona, just stay in your Honda (Video) Rand McNally 07/13/2012 Comments off Who knew that there could be hail in Arizona? We made it through the trauma, and have a few words of wisdom... Read More (VIDEO) Not a Town for Beach Bums – Fun in Delray Beach, FL Rand McNally 07/13/2012 8 Comments You're not gonna find beach bums in this little beach town. A vibrant nightlife coupled with a plethora of daytime activities, Delray... Read More Eating Local near Denton, TX: Ham Orchards Rand McNally 07/13/2012 Comments off Eating Local near Denton, TX: Ham Orchards http://www.hamorchard.com by Patricia Serrano On our way to Denton, TX we stumbled upon a roadside... Read More (VIDEO) Fresh Traveler Visits Santa Claus, IN! Rand McNally 07/13/2012 Comments off Christmas everyday? Yes, this is possible in Santa Claus, IN. Check out our summer Xmas adventures!... Read More Best of the Road: Fresh Traveler on Denton, TX Rand McNally 07/12/2012 1 Comment Reckless, irresponsible, and even possibly dangerous…. but SO MUCH FUN! Doing reckless, irresponsible, and possibly dangerous activities seems to be the consensus... Read More 123


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On the road to WrestleMania and as a part of the biggest weekend of the year in the world of wrestling, there is another annual tradition, the Hall-of-Fame ceremony.
Year after year, one big name is inducted into the WWE Hall-of-Fame, and some other legends in their own are also added to the induction list.
This year, Shawn Michaels is the leader of the class. And, so far, we know the names of three other wrestling personalities who will make it in HBK's shadow.
"Hacksaw" Jim Duggan, "Bullet" Bob Armstrong and Sunny all deserve their spot, there is no doubt, but they are not in Michaels' league.
Not many automatically associate Duggan to the Hall-of-Fame unlike someone like Stone Cold or Hulk Hogan who are obvious picks. It's not a matter of disrespect for those who are not the leaders of their class, but some choices are not always obvious and that is where I want to go in the following slideshow.
The Undertaker, Triple H, John Cena and some others already have their guaranteed first-class ticket for a future Hall-of-Fame ceremony. However, there are also some other wrestlers of less magnitude who will accompany the sure things.
Obviously many names will be missing and I hope to hear from you in the comment section about who should be on the list. I wanted to keep it at 10 to only get my actual sure picks and to avoid the easy way by getting it to 20.
So, let's see who I think have a good chance to make it into the WWE Hall-of-Fame eventually.


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2012 London Olympics: what countries will win the most medals in boxing?
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I always thought Cuba had the best olympic boxers?
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Cuba, known to pack the mightiest punch in Olympic boxing during the past half century, arrived in Beijing with its most vulnerable squad in recent memory after a string of defections stung the team like a Teofilo Stevenson right hook.
For the first time in 40 years, Cuba did not qualify a boxer in all 11 Olympic weight classes.
In the past two years, the Cuban team lost five gold medallists from the 2004 Athens Olympics and a 2005 world champion. Four defected and are boxing professionally, one was punished for attempting to flee, and another retired.
The island boasts an illustrious lineage of boxers, and the sport has long been a source of pride - and a political propaganda tool - for the Cuban government.
Fidel Castro banned professional boxing in 1962, calling it corrupt and exploitive. Boxers in Cuba were then restricted to amateur competition, and many of them fought into their early 30s while their contemporaries from other countries moved on to pro careers.
Of Cuba's 65 Olympic gold medals, 32 were won by boxers. The number would be even higher had Cuba not boycotted the 1984 and 1988 Olympics.
An Olympic title was once the ultimate prize for a Cuban boxer, and champions such as Stevenson and Felix Savon, who won three gold medals each, were held up by Castro as national heroes who spurned millions of dollars to remain in Cuba and fight for patriotism and socialism.
When boxing promoter Don King offered Savon a contract reported to be $10m, Savon said, "Why would I box for a $1m when I can fight for 10 million Cuban people?"
But the deteriorating economic conditions in Cuba and a changing attitude among some young athletes led to the exodus after the 2004 Olympics.
"Gold medals are wonderful, but athletes can't eat their gold medals," said Miami-based boxing trainer Roberto Quesada, who coached in Cuba from 1980 to 1991 before defecting.
Three of the reigning Olympic champions - heavyweight Odlanier Solis, flyweight Yuriorkis Gamboa and light flyweight Yan Barthelemy - sold their medals to buy food for their families in Cuba and then bolted from a team training camp in Venezuela in December 2006.
They signed pro contracts with a German promoter. Gamboa and Barthelemy train under Quesada in Miami, and all three were undefeated as pros until Saturday night, when Barthelemy lost.
Bantamweight champ Guillermo Rigondeaux was dropped from the Cuban squad after trying to defect during the 2007 Pan American Games in Brazil. Lightweight gold medallist Mario Kindelan retired. And 2005 welterweight world champion Erislandy Lara, whose plan to defect with Rigondeaux was botched, left Cuba on a speedboat to Mexico in May and recently signed a pro contract in Germany.
"The circumstances force you to make sacrifices, and it's a shame," Barthelemy said. "In the old days, Olympic athletes were well taken care of and lived a more privileged life in Cuba, but things had gotten so bad that we weren't much better off than anyone else. I was worrying about food for my family. The only difference was that we got to travel and see how the rest of the world lives.
"I will always be Cuban and proud of my heritage, but I had to follow my dream."
Unlike Cuban teams of the past, which were loaded with veterans, this group has limited international experience. Only two - lightweight Yordenis Ugas and heavyweight Osmay Acosta - are considered gold-medal favourites.
The team did not travel to Chicago for the 2007 world championships because Cuban officials feared more defections.
"We will not expose a Cuban team again to the excesses and provocations that in this case would occur in Chicago, in US territory, an ideal location for merchants and traffickers to act freely with the complicity of US authorities," the Cuban federation said in a statement at the time.
Quesada said participating in the world championships is excellent preparation for the Olympics because boxers learn to pace themselves in a tournament that lasts two weeks and make weight five or six times, which is different from preparing for one bout. They also can scout the competition.
"I wouldn't say the Cuban boxers are weak, because even when they lose great fighters, there are other ones coming up behind them, but this team is not as experienced as they've been before," said US assistant boxing coach Mike Stafford, who trains Olympian Rau'shee Warren.
"And the defections might continue because kids are more aware of the world now with the internet. Promoters are going after those Cuban kids, and it's hard to keep them from chasing their dream.
"The government took care of Felix Savon, and he was very loyal, but those were different times. I have trouble keeping kids amateur in my gym, so imagine how hard it is in Cuba."
Cuban sports officials are cautiously optimistic about their chances. They are not talking about medal predictions, except to say they want Cuba to finish in the top 10 overall among all nations, which it has done in five of the past six Olympics in which it participated. The Cubans slipped to 11th place in Athens four years ago.
"We have completely renovated the team," boxing coach Pedro Roque told reporters in Havana. "We can't talk at this moment about grand goals or compare them with the Athens team - this team will enjoy their experience in the ring without thinking about medals."
In a recent Prensa Latina report, Cuba Boxing Federation president Jose Barrientos said, "The situation today is very similar to that of Barcelona 1992, when we arrived with no Olympic experience due to our absence in Los Angeles 1984 and Seoul 1988 and returned with seven gold medals."
Other Cuban teams have also been affected by defections.
Seven members of the Cuban Under-23 soccer team fled from a Tampa hotel in March while competing in the Olympic qualifying tournament.
The team was left with only 12 players, and it did not advance to Beijing.
The Cuban judo team suffered a big blow when two-time world champion and Olympic gold-medal favourite Yurisel Laborde, a bronze medallist in Athens, deserted the team in Miami.
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I know America will have the most medals for the entire Olympic Games at least. America's amateur program is struggling a bit, but still has the best professionals hands down.
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Nobody cares about Amateur boxing anymore, anyway. The scoring system is absolutely f*cking terrible and it makes the sport unwatchable, IMO. Good luck to all the amateur boxers going to London this year, but like the rest of the world - I won't be watching you.
Come see me when you're pro.
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Find an article comparing cuba to the world, not to itself
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My biased opinion.
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It's actually the U.S that have the most medals in boxing lol
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Ukraine has two really good fighters coming into the games, Cuba should be up there as well. The UK isn't a nation, but there will certainly be a strong bias, like there was in China for their fighters.
As for the American team, they have a chance to do very well. The team they are sending to this Olympics is probably their most talented since 1996. Not sure how many medals that equates to, but they will certainly do better than they did China.
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By Shane McGlaun
Digital photo frames may seem boring, but anyone who takes lots of digital pictures will find that the gadgets are a great way to do something with all those pictures other than letting them sit on your computer or memory card. The price of digital photo frames are coming down as well making them more affordable.
Samsung has announced a new digital frame that is under an inch thick and sports an 8-inch screen. The screen has a resolution of 800 x 480 and a contrast ratio of 500:1. Despite the small size of the frame, it packs 1GB of memory inside.


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Monday 30th June - Thursday 3rd July 2008
Mansfield College, Oxford
Call for Papers
This inter-disciplinary and multi-disciplinary conference seeks to examine and explore issues surrounding visual literacy in regard to theory and praxis. Perspectives are sought from those engaged in the fields of education, visual arts, fine arts, literature, philosophy, psychology, critical theory and theology. These disciplines are indicative only as papers are welcomed from any area, profession and vocation in which visual literacy plays a part.
Papers, reports, work-in-progress and workshops are invited on issues related to any of the following themes;
* the concept and tools of visual literacy
* pre-school children and visual literacy
* visual literacy and cultural identity
* interpreting elements and examples of visual literacy
* visual literacy as therapy
* the liminal elements and facets of visual literacy
* social and cultural reactions to visual literacy
* visual literacy in literature
* visual literacy in television and film
* visual literacy and the media
* visual literacy as a social semiotic
* teaching visual literacy
* visual literacy as deformed discourse
* theology and visual literacy ñ use and/or abuse
* teleology and visual literacy
* the history of visual literacy
The Steering Group particularly welcomes the submission of pre-formed panel proposals. Papers will be considered on any related theme. 300 word abstracts should be submitted by Friday 1st February 2008. If an abstract is accepted for the conference, a full draft paper should be submitted by Friday 6th June 2008.
300 word abstracts should be submitted to both Organising Chairs; abstracts may be in Word, WordPerfect, or RTF formats, following this order:
a) author(s), b) affiliation, c) email address, d) title of abstract, e) body of abstract
We acknowledge receipt and answer to all paper proposals submitted. If you do not receive a reply from us in a week you should assume we did not receive your proposal; it might be lost in cyberspace! We suggest, then, to look for an alternative electronic route or resend.
Joint Organising Chairs
Dr Phil Fitzsimmons
Faculty of Education
University of Woollongong
Email: firstname.lastname@example.com
Dr Rob Fisher
Priory House, Freeland, Oxfordshire OX29 8HR
United Kingdom
Email: firstname.lastname@example.com
All papers accepted for and presented at this conference will be eligible for publication in an ISBN eBook. Selected papers will be developed for publication in a themed hard copy volume.
The conference is sponsored by Inter-Disciplinary.Net as part of the 'Critical Issues' programme of research projects. It aims to bring together people from different areas and interests to share ideas and explore various discussions which are innovative and exciting.
For further details about the project please visit:
Fir further details about the conference please visit:


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Sass & the City: Christmas needs to wait its turn
Dear Christmas:
My name is Halloween and I am writing this letter to ask you to please just back off.
Really. Here we are at the end of October and you're already getting all the attention.
I went up to the mall, expecting to bask in orange and black d�cor, phony spider webs and cheesy witch posters. But nooooo. Everywhere I looked, I saw nothing but red and green and a fat guy who forgot to shave.
Houses that are supposed to be lit up with strings of jack-o'-lanterns are already sporting Christmas lights.
Wait your turn.
Stores are already advertising early Christmas sales. Meanwhile, trick-or-treat candy, goblin d�cor and the Halloween costumes everybody wants are rocking full-price tags.
Give me a break.
It's not easy being Halloween. And, if you can stop humming fa-la-la-la-la long enough, I'll tell you why.
When it comes to the weather, everyone expects me to be perfect. But not you. If a snowstorm rolls in on Christmas Eve, everyone acts like free money is falling from the sky. But if there's so much as a flake at Halloween, parents totally bail on me and let their kids trick-or-treat at the mall. Probably so they can Christmas shop.
At Christmas, everyone is all lovey-dovey and peace-on-earthy. But try being Halloween for a nanosecond -- the holiday during which people actually check the candy treats for razor blades. When was the last time someone checked a freaking snickerdoodle for a sharp object? Am I wrong?
At Christmas, people drive around to admire the holiday lights, and after Christmas, the decorations are lovingly tucked away until the following year. But what happens to jack-o'-lanterns? Mmm-hmm. There's even a band named after it.
Even the Christmas soundtrack is premature. Some radio stations are already sneaking in carols. But Halloween songs? Not a chance! I haven't heard "Monster Mash" since the 20th century. And when was the last time you saw a Halloween caroler?
With all this in mind, please just move the heck over and stop being such an attention hog.
PS: I hear letters from Veterans Day, Thanksgiving and Hanukkah are forthcoming.
Follow Monica on Twitter at twitter.com/sassnthecity or e-mail her at email@example.com.


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Arts & Life
New luxury dog hotel is probably nicer than your place
Photo: Maelyn Schramm
The Pooch Hotel's Spaw area features aromatherapy bathing and massage, paw-dicures, Poochberry facials and tooth brushing.
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What poetic devices are used in "The Raven"?
1 Answer | Add Yours
Perhaps the most prominent poetic device used in "The Raven" is alliteration. This use of alliteration seems to thrust the poem forward, as if hastening to a conclusion. Good examples are:
And the silken, sad, uncertain...
...filled me with fantastic terrors...
The most brilliant use of alliteration in all poetry is to be found in these lines:
Then, methought, the air grew denser, perfurmed from an unseen censer
Swung by seraphim whose foot-falls tinkled on the tufted floor.
The "s" sounds begin with "denser" and recur in "unseen," "censer," "Swung," and "seraphim." They are followed in the second line by "f" sounds in "foot-falls" and by "t" sounds in "tinkled" and "tufted."
There are many internal rhymes throughout the poem, beginning with:
Once upon a midnight dreary, while I pondered, weak and weary...
Poe uses similes and metaphors throughout "The Raven." For example:
...and his eyes have all the seeming, of a demon's that is dreaming...
Poe's major contribution to poetry was in his symbolism. The raven obviously symbolized death. The French, especially through Charles Baudelaire, were so capitivated by the innovation that "symbolisme" became a major movement in French poetry. Poe explains his theory of poetry with special attention to his composition of "The Raven" is an essay titled "The Philosophy of Composition" (see reference link below).
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Hi! My name is Grayson
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Where I hang out: Wherever my human is, that is usually where I am!
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On Saturday, May 10, over 70 teams will participate in the 31st annual World Series of Birding, hosted by New Jersey Audubon (NJA).
The World Series of Birding is a competitive "Big Day" for birding and nature enthusiasts. Teams have up to 24 hours (from midnight to midnight) to count as many bird species as they can identify by sight or sound within the state of New Jersey. Each species seen or heard counts as one. NJA lays the ground work and gives participants, the playing field and rules to follow – and the rest is up to the teams.
World Series of Birding has changed the birding landscape, drawing attention to the habitats of migrating birds; giving birders a chance to put their bird watching skills to use for a good cause by focusing global media attention upon the challenge, adventure, and fun of bird watching.
Most importantly, the event generates a great deal of money for conservation causes. People directly donate to support the event or pledge their favorite team an amount per bird species seen/heard during the event raising over $600,000 annually – a total of $9 million over its 31-year history. The money raised is put back into our surrounding environment in ways that protect resources and preserve the habitats that the birds need.
For more information about the World Series of Birding, visit njaudubon.org or call René at 609.861-1608, exy. 13 or email email@example.com.


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Go Local
Grace Point's goal is to impact our local community for Christ by encouraging our members to go and serve outside the walls of the church.
We seek to minister to the unique needs of our community around us with the resources that are unique to Grace Point, prioritizing EVANGELISM as the best way to see lives transformed and God glorified.
For information on any local opportunity, contact Moe Lane at firstname.lastname@example.com or 210-558-5919.
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