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350 West 39th Street
New York, NY 10018
Tel: (212) 946-4000
Fax: (212) 946-4010
R/GA is an interactive agency that specializes in delivering award-winning creative, global strategies and complex software development
MasterCard launches interactive outdoor sweepstakes campaign
MasterCard launched an out-of-home campaign on Aug. 1 that integrates QR codes and Facebook Places to enable consumers to enter a sweepstakes.
L'Oreal names R/GA digital AOR for luxury brands
L'Oreal has named R/GA digital AOR for its luxury products division in the US, the brand said May 12. The agency will be responsible for L'Oreal's comprehensive digital strategy and execution for a number of consumer product brands.
McCormick & Co. names R/GA digital AOR
Food products distributor McCormick & Co. has named R/GA its digital AOR after an RFP process. The agency search took place last fall and involved four agencies, said Laurie Harrsen, director of PR and consumer communications at McCormick.
R/GA names Charnock chief strategy officer
R/GA hired William Charnock as chief strategy officer, a newly created position, effective January 25. Reporting to Bob Greenberg, agency CEO and global chief creative officer, he will oversee the agency's global strategy and manage its strategy, planning and research teams.
Ameriprise taps R/GA as AOR
Financial planning company Ameriprise Financial announced December 2 it has chosen interactive agency R/GA as its agency of record, handling traditional advertising and digital. The first creative from the partnership will debut in early 2010.
Company of the Week
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text: The Superconducting Materials Group in the Materials Department has since 1987 been active in the synthesis and fabrication of HTS materials in practically applicable forms. The group, currently led by Prof. Chris Grovenor and Dr. Susie Speller, has strong links with the HTS Communications Group in the Department of Engineering Science led by Professor David Edwards, and works closely with other research groups in Oxford based at the Clarendon Labs. In addition the group collaborates with other UK research groups (Cambridge, Leeds and UCL) and internationally (Turkey, Slovakia).

subset: commoncrawl


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Patch v1.11 for Korsun Pocket has just been released. You can download it from our downloads section or via our True update feature that comes with Korsun Pocket. The patch fixes a few glitches in various scenarios.
Posted: Tuesday, December 09, 2003 by Shaun Wallace
Type: Update
Patch v1.11 for Korsun Pocket has just been released. You can download it from our downloads section or via our True update feature that comes with Korsun Pocket. The patch fixes a few glitches in various scenarios.
( Views : 8670 )
Back when we released the U.S. Corps packs we told you they would be the last DLCs for the Panzer Corps series, but we never said that the path of Panzer Corps had come to an end. Millions of people enjoyed Panzer Corps in the last few years: it's been a long and epic ride, but it's not over yet.
The dispute over the Spratly Islands in the South China Sea has reached a turning point.
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The Command LIVE News Team has just sent his last reportage, directly from the frontline!
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Are we close to an open conflict in the South China Sea?
This has been a week full of important news!
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The hit Order of Battle: World War II will be expanded with a new campaign DLC focused on the first blitzkrieg wars of Germany in the Second World War, and a free major update!


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Behind the scenes
In the romantic comedy "Playing for Keeps," Gerard Butler plays an ex-soccer superstar (George Dryer) who moves to suburban Virginia to start over -- and start a relationship with his son, whom he barely knows. Co-stars include Jessica Biel, Catherine Zeta-Jones, Uma Thurman, Judy Greer and Dennis Quaid.
"I knew right away this was something I want to get involved with," Butler said. "I thought, 'We can move people with these characters and we can definitely make them laugh.'"
"I felt a lot of emotional attachment to (the story) and I could really identify with George and the journey he takes -- unraveling and then putting his life back together."
"It was a lot of work. I did what I love to do, which is get obsessed by it. Every time I saw a ball, I would start messing around with it. I had the best time and I just want to play soccer all the time now."
SOURCE: Film District


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Treatments for melasma include photoprotection in conjunction with topical agents such as hydroquinone, retinoids, or combinations. These regimens, while reasonably effective, are hindered by adverse effects such as irritation and ochronosis.1,2 Aggressive topical sunscreen use improves melasma as monotherapy.3 However, compliance with frequent sunscreen application is difficult; a more convenient and effective photoprotective regimen is needed. We assessed the effectiveness of Polypodium leucotomos extract (PLE), an oral, commercially available UV radiation protectant, as an adjunct to once-daily topical sunscreen application in the treatment of melasma.
The sample size was calculated from results of a previous study using topical hydroquinone in which patients with melasma improved significantly with daily application of hydroquinone, 4%, cream with or without 4 salicylic acid peels over a period of 8 weeks.4 The primary end point was improvement in the melanin index, defined as the difference between pigmented and adjacent normal skin using narrowband reflectance spectrophotometry (Mexameter; Courage and Khazaka Inc). For our treatment group, we estimated the mean (SD) improvement in the melanin index compared with that in those receiving placebo to be 11.7 (13.0) points, based on the reported findings of Kodali et al.4 A sample size of 20 patients per study arm was required to detect this difference, assuming a type I error of 0.05 and 80% power, using a 2-sided, 2–independent sample t test.
We recruited Hispanic women with melasma via announcement on a Spanish-language news station in Dallas, Texas. Approximately 125 subjects were screened, and 40 were enrolled. Subjects were required to have a diagnosis of moderate to severe facial melasma, defined as a melanin index of 30 or greater. Pregnant and lactating subjects and those who recently used other treatments for melasma were excluded. The study protocol was approved by our university institutional review board.
The 40 subjects were randomized to receive either 240-mg doses of oral PLE or placebo 3 times daily for 12 weeks. All subjects were given a standard, broad-spectrum, topical sunscreen (sun-protection factor, 55) to use every morning. The primary outcome measure was change in melanin index from baseline at weeks 6 and 12. Assessment of melasma area and severity index (MASI) and melasma-related quality-of-life (MelasQOL) were performed as secondary end points. All assessments were performed by blinded investigators. All subjects commenced study participation in May 2010 and completed the study in August 2010.
Thirty-three of 40 subjects completed the study (16 in the PLE group and 17 in the placebo group). There was no significant difference between the 2 groups regarding age, duration of melasma, or Fitzpatrick skin type. Both the PLE and placebo groups showed significant improvement in melanin index between weeks 0 and 12, with 28.8% improvement in the PLE group, and 13.8% improvement in the placebo group (Figure 1). However, the intergroup difference was not statistically significant (P = .14). The MASI scores (Figure 2) similarly showed improvement in both groups between weeks 0 and 12, without significant intergroup difference (P = .62). The MelasQOL scores (data not shown) showed minimal change in either group. Both groups tolerated the treatments well.
Improvement seen in both groups at weeks 6 and 12 but no significant intergroup difference. ANCOVA indicates analysis of covariance; ANOVA, analysis of variance; PLE, Polypodium leucotomos extract.
Improvement seen in both groups at weeks 6 and 12 but no significant intergroup difference. ANCOVA indicates analysis of covariance; PLE, Polypodium leucotomos extract.
The results of our study do not support the premise that oral PLE is effective as an adjunct to topical sunscreen in the treatment of melasma in Hispanic women. Both the primary and secondary outcome measures failed to show a significant difference from placebo. Using a clinically meaningful effect size, this study was powered to detect a difference of 11.7 points in melanin index in the PLE group compared with placebo. The actual difference between the groups was less than half of the original estimate (5.1 points) and not statistically significant. We do not believe this small improvement is enough for most patients to be interested in purchasing and ingesting an oral medication 3 times daily.
To our knowledge, the efficacy of sunscreen alone in the treatment of melasma has never been quantified. From evaluation of the placebo group, we conclude that once-daily use of topical, broad-spectrum sunscreen for 12 weeks results in a 14% improvement in the darkness component of melasma.
In sum, we conclude that oral PLE is well tolerated but not significantly better than placebo as an adjunct to topical sunscreen in the treatment of melasma in Hispanic women. Topical sunscreen alone, even with just once-daily application during summer months, results in mild improvement of melasma.
Corresponding Author: Ammar M. Ahmed, MD, Department of Dermatology, University of Texas Southwestern Medical Center at Austin, CEC C2.443, Austin, TX 78701 (firstname.lastname@example.com).
Accepted for Publication: February 12, 2013.
Published Online: June 5, 2013. doi:10.1001/jamadermatol.2013.4294.
Author Contributions: Dr Ahmed had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
Study concept and design: Ahmed, Pandya.
Acquisition of data: Ahmed, Lopez, Perese, Vasquez.
Analysis and interpretation of data: Ahmed, Hynan, Chong, Pandya.
Drafting of the manuscript: Ahmed, Lopez, Perese, Vasquez.
Critical revision of the manuscript for important intellectual content: Ahmed, Hynan, Chong, Pandya.
Statistical analysis: Hynan.
Obtained funding: Ahmed, Chong.
Administrative, technical, and material support: Ahmed, Lopez, Perese, Vasquez, Pandya.
Study supervision: Ahmed, Perese, Chong, Pandya.
Conflict of Interest Disclosures: None reported.
Funding/Support: This study was supported by a grant from the Skin of Color Society. Polypodium leucotomos extract capsules and placebo were donated by Industrial Farmaceutica Cantabria SA, Madrid, Spain. Sunscreen was donated by Aveeno, Johnson & Johnson Consumer Companies Inc.
Role of the Sponsors: The sponsors had no role in the design and conduct of the study; in the collection, analysis, and interpretation of data; or in the preparation, review, or approval of the manuscript.
Additional Contributions: We are indebted to Heidi Jacobe, MD, for advice regarding study design, and Mia Ashe-Randolph and Memoree Lee for administrative assistance.
Trial Registration: clinicaltrials.gov Identifier: NCT01092884.
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Which length of Bull barrel for an AR?
Tools and Technologies
Rifle Country
> Which length of Bull barrel for an AR?
March 25, 2008, 08:17 AM
I want an AR with a bull barrel for long range target shooting, in .223. Which would inherently provide the best chance for accuracy, a 16" or a 20"? Is there that big of a difference?
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March 25, 2008, 09:05 AM
20" for higher muzzle velocity and longer sight radius.
1:8" twist or faster for heavy bullets.
March 25, 2008, 09:09 AM
18 inches will get you all the velocity you can get from a 223 as long as you load the rounds with the correct powder for the bullet weight you are shooting. Most are 20 inches, some are 24...and 24 is definately a waste (except from a sight radius standpoint...and if you use a scope, that point is moot).
March 25, 2008, 09:28 AM
24 isn't a waste. If he is reloading and wants to wring everybit out of that 223 a 24 in is the way to go. that said they are long and heavy. 20 inch is a happy medium. I wouldn't even consider a 16 for a target gun.
As far as sight radius its a moot point bull barrles very seldom have open sights on them.
March 25, 2008, 10:09 AM
I can get just as many FPS from an 18 or 20 inch as you can from a 24....just with different powders.
How many fps can you get from a 24 inch with a 60 grain bullet???
I can get over 3,000 fps from a 16 inch barrel and a 60 grain Hornady V-MAX bullet...the 223 does not have the case capacity for barrels that long...but people want them, so companies make them.
March 25, 2008, 11:23 AM
Is the gas block in the same place on 18, 20, 24 inch barrels?
What does that pressure drop do to the MV?
March 25, 2008, 12:21 PM
Yes they all have rifle length gas systems.
The pressure drop occurs too late to have any noticeable effect.
March 25, 2008, 01:49 PM
Ridgerunner, you must be using faster powders to get 3000fps out of a 16" with a 60gr bullet. Are your cases showing any signs of high pressure fatigue?
I wanted a varmint-specific AR, so I bought the Stag model 6. It has a 24" bull barrel but after I shoot that a while I wouldn't be averse to chopping a few inches off and rechambering for AI.
March 25, 2008, 05:54 PM
So a 20" would be best, over a 16"?
March 25, 2008, 06:38 PM
Buy what you want, they all shoot.
Varmint Loads - 223 Remington
March 25, 2008, 08:06 PM
AA2230 was the powder used for that load...one thing I should mention is that my gun has a 5.56 NATO chamber...the 223 Remington chambered guns can only be loaded to 50,000 psi..some say 52,000, while the NATO version can be loaded to 60,000 psi.
With plain CCI small rifle primers...that load will flatten them just a little...but with CCI 41 primers, which are made just for 5.56x45 mm, they are just fine. Of course case life is shorter, I load them 2 maybe 3 times.
If you're havving a gun built or buying one...be sure to get either a 223 Wylde chamber or a 5.56x45 chamber...not a 223 Rem. chamber.
And...yes a 20 inch barrel is PLENTY long enough for a varmint or target AR...18 would do just as good.
March 25, 2008, 08:24 PM
Here is a link to a thread over on 1911auto forum...posts #25 and #26 are especially interesting
My learning experience of reloading for a 5.56x45 mm is documented online...I got tired of settling for 223 Rem loads... 5.56x45 loading info is scarce...but if you look hard enough...its there.
BTW...Feel free to join the 1911auto forum while you're over there...its only been there since this past December, but its growing fast... its a nice place, with a crew of really nice guys running it.
March 25, 2008, 08:34 PM
I'd go with an 18, I think 18s are under appreciated. Troops are beginning to use 18 inch DM rifles with 70-grain rounds successfully in the sand box.
March 25, 2008, 08:45 PM
The military spent a lot of time and money to figure out that 18 inches was the optimal barrel length for an m16...and that was over 30 years ago. Due to the advancements in powders...its even more true today than it was 30 years ago.
March 25, 2008, 11:21 PM
ridgerunner, since this isn't in the reloading thread, where there are warnings about posting load data above maximums, i feel obliged to say i think you need to be careful with this advice.
accurate's max published load using a 24" barrel is 3024 fps using 2230 and the 60g hornady. Given that you lose ~100 fps going from a 20" to a 16" barrel and probably another 100 fps going from 24" to 20", I can only assume you're loading well above maximum.
I know there are those here who like to push limits, but telling folks they can use load data that puts you 200 fps over the published maximum is treading close to irresponsible. especially after reporting pressure signs in your own loads.
as you may know, many mfgs mislabel their chambers/barrels. it's generally unwise to arbitrarily bump your load up because you think one chamber can handle 10k more PSI than another. and that assumes you have the equipment to measure pressure.
March 25, 2008, 11:43 PM
I want an AR with a bull barrel for long range target shooting, in .223. Which would inherently provide the best chance for accuracy, a 16" or a 20"? Is there that big of a difference?My 75gr Hornady OTM loads clock out at about 150fps-175fps slower in my 1:9 16" Armalite barrel (5.56 chamber) than they do in my 1:8 20" Shaw barrels (with a 223 chamber).
Also - always keep in mind that bolt guns and semiautos are different beasts. Anyone shooting an AR with a range of handloads knows that port pressure and dwell time differences between loads can cause significant functional stresses and anomolies. In fact, the Sierra loadbook has a completely separate section for 223 in boltguns vs semiautos, for this very reason. You can play with loads in a bolt-gun in ways that are simply Not Good JuJu for an AR15.
I prefer to get velocity thru barrel length rather than abnormally high chamber pressures. It's easier on the equipment, and for a range/target rifle I don't mind a little extra weight due to the longer tube.
Having said that - shorter barrels are sometimes actually more accurate (they just make a little less velocity).
If you're looking for max range, I'd definitely go with a 20". If you're looking for the ultimate accuracy within, say, 200-300 yards then the 16" may give you a minor increase in accuracy at the expense of some trajectory drop downrange.
March 25, 2008, 11:52 PM
I measure pressure by measuring the case heads for expansion...the warnings are there...I did say that my gun DOES have a 5.56 chamber...these loads are above max for a 223 Remington...but they are right on for a 5.56x45.
You haven't listened to what I've been saying...you do not lose 100 fps by going to from a 16" to a 20"...neither do you lose another 100 fps by going from a 20" to a 24" when your gun is chambered in 5.56x45...I'm not talking about a 223 here...223 load data is useless for any AR chambered for a 5.56x45...except maybe for plinking ammo or to use as a start charge for a 5.56x45.
Yes some makers may not mark their barrels correctly...its only a few $$$ for a smith to tell you for sure...thats up to the owner (and only then if they purchase a rifle from somebody who would mark their barrels wrong).
The only reason I had any pressure signs with my loads was because I used CCI 300 primers...there were no flat primers when I used the CCI 41 primers.
I don't think my chamber can handle 10k more PSI...I know it can, because of the company that built my AR and what they built it for.
I see your point...but a person should have the common sense to either know what they bought...or at least be able to find out, its not that hard to do.
March 25, 2008, 11:55 PM
rbernie...those heavy bullets are another monster...they do need the extra barrel length (and slower powders) to get going.
March 26, 2008, 12:11 AM
I'm going to say one more thing on this thread then I'll shut up since it seems that hard earned knowledge isn't welcome here.
Whats the point in having a 5.56x45...if you're going to load it with 223 ammo.
March 26, 2008, 12:13 AM
I use an AR with a 20 inch bull barrel for NRA Highpower competition. It does well out to 600 yrds with iron sights.
I've tried an 18 inch and it didn't perform nearly as well. I haven't tried anything longer.
I've never seen an 18 incher on the line at camp perry.
Art Eatman
March 26, 2008, 12:58 AM
Ridgerunner, don't take this as any sort of personal slam:
This is the Internet. Nobody can tell if any one person is correct or not without some lengthy track record of posts and feedback over time.
The possibilities of Ridgerunner's system may work. We have no way of knowing if he's one more shot away from a damaged rifle. I'm not at all predicting; I'm saying we don't know as fact.
If anybody wishes to follow his suggestions, fine. However, as with any load development, start low and buildup slow. Do NOT jump in and immediately follow the notion of, "Well, he said he loaded it like this, so I can do the same."
I note in passing that the strength in shear of the lugs of a bolt-action rifle is greater than of the AR-15; more cross-sectional area. For a push-feed action, there is no benefit to 5.56 over .223.
I will take exception to the comments about barrel lengths and velocity loss. For there not to be a loss from 24" to 20" or from 20" down to 16", it would be the first time in my 58 years of messing with centerfire rifles that this has occurred.
There have been numerous experiments where barrels were cut back an inch at a time and a chronograph was used. Shorter = slower, invariably. And a centerfire .22 is a centerfire .22, no matter how you meddle around with the loadings.
March 26, 2008, 01:06 AM
I had the same question a few years ago and got the 20". More velocity and less muzzle blast. Also shoots very small groups!
March 26, 2008, 01:42 AM
Art...Thank You
I dont take it as a slam.
I should clarify something I don't think I have made clear though....with the exact same load, you will lose fps in a shorter barrel...but most of the time, by matching your powder burn rate to your barrel length and bullet weight...you can match the velocity of the longer barrel. The real fast powders with heavier bullets in long barrels for example, the pressure drops and the bullet starts slowing down before it even exits the barrel. This is especially true when talking about cartridges with a small case capacity.
I get in trouble every time I start talking about reloading.
And just for the record...I didn't post any loads on this thread...the loads on the other thread are full of red letter warnings.
March 26, 2008, 11:50 AM
Ridgerunner - I think you only got jumped on here because you only focused on velocity and not bullet weight. You can get 3k with a 60gr V-max out of 16, but I can easily get 3k with a 75gr A-max in my 26" white oak barrel. And when varminting is the game, a heavier bullet will obviously let you reach out a bit farther with less drift.
March 26, 2008, 09:34 PM
Ridgerunner, I am curious where you have found your information about bullets slowing in the barrel when using faster powders. This contradicts most everything I have ever seen regarding modern bottleneck rifle cartridges.
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Waldo Fabian Garrido
A bassist, composer, singer, re-mixer and producer who has worked with various pop, latin and jazz bands plus various outstanding musicians.
Waldo Fabbian was a founding member of the Catholics. He is a bassist, composer, singer, re-mixer and producer who has worked with various pop, Latin and jazz bands and musicians such as The Party Boys, Floyd Vincent, Disco Montego, Delta Goodrem, Swoop, Anthony Copping and Robin Loau as well as having two solo albums to his credit (Dejame Tocarte, a South American release through Sony and Loco Festival/Mushroom records).
Waldo has enjoyed No.1 single status on Chile's premier station, Radio Corazon with two songs. His song Fiesta Latina picked at number 12 in the Aria Club Charts in Australia.
An active writer, Waldo is currently getting ready to start promoting his brand new album Groovy Cumbia due out in September 2012 through MGM plus completing a jazz album and writing and producing dance songs for the new Australian dance label Komplex Sounds.
His versatility also includes writing film scores including Random 8, winner of a Bronze Palm in the Feature Narrative section of Mexico International Film Festival and on Emma-Kate Croghan's film Strange Planet.
Waldo is currently finishing his PhD at Macquarie University under the supervision of Dr Andrew Alter where he also lectures and tutors in a number of units in music. He also held tenure as an associate lecturer at Southern Cross University and his results of his thesis will be released as a CD and published as a book.
As an academic, Waldo has written and published a number of peer-reviewed articles, book chapters and presented various conferences on popular music, small island studies and music psychology. He is working on a number of publications with world renowned academics like Professor Philip Hayward, Professor Bill Thompson, Associate Professor Mark Evans, Dr. Nicholas Bullot, Dr. Dan Bendrups and Sandra Garrido amongst others.
Waldo is currently writing a book on the history of music publishing in Australia as well as conducting a number of research projects on popular music, small island studies, music production and music psychology.


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Soccer: Alyssa Ables' Hawaiian Blog Day 4
Senior midfielder Alyssa Ables has been documenting the Ball State soccer team's experience in Hawaii on this blog. Today she writes about the team's last day on the island. Without a game on Sunday, the team was able to take in more of the sights.
Ball State wrapped up play Saturday night at the Outrigger Hotels and Resorts Classic with a 1-1 draw versus Detroit. The Cardinals also earned a 1-1 draw versus Hawaii in the first game of the tournament.
Blog Entry #4 (Sunday) - Final Day in Hawaii
Photos from Day 4
Our last day in Hawaii was a blast!! With no game to prepare for, we were able to relax and just enjoy ourselves. The morning started off with Emma Crenshaw and Maimee Morris greeting the team at breakfast with their grass skirts and coconut bras on! They showed off a few hula moves, and we all laughed as we ate our breakfast.
First thing on the itinerary for the day was snorkeling! The team was so excited to spend some time in the water and on the beach for the first time. We took lots fun, goofy pictures with our snorkeling gear on, and many of us joked about looking like Scuba Steve from the movie Big Daddy. We snorkeled for a couple hours and saw lots brightly colored fish, a sea turtle, and even an octopus. We all loved this experience, especially Amada Dreyfus who said she thought she was in heaven!
After our snorkeling fun was over, we headed back to the hotel to get ready for a nice Hawaiian lunch. We all put on our cute outfits and left for lunch. We went to an amazing restaurant, where we had the opportunity to try various types of seafood and Hawaiian desserts. We all enjoyed getting the chance to try some Hawaiian cuisine and were stuffed at the end of the meal.
After lunch it was time to head back to the hotel one last time to pack and prepare for our journey back to Ball State. The team had a great trip, and we all feel truly blessed to have had this opportunity. We grew together as a team in Hawaii, and as a senior I can honestly say the memories I have made here are ones that will last a lifetime!
Chirp Chirp!
Blog Entry #3 (Saturday) - Pearl Harbor and Another Game
Photos from Day 3
Day three was another adventurous day in Hawaii! We started the day off by going on a team jog along the beach near the hotel. It was a great morning, and the weather was really nice. When we were finished with our jog and stretch for the day, we loaded up the vans and we were off to our first destination.
Our first stop for the day was at Pearl Harbor. The tour began with a documentary about the days before and after the bombing of Pearl Harbor. We were then taxied by boat out to the memorial site where the USS Arizona sank. We had the chance to see what remains of the ship and learn more about the different aspects of the memorial. This was a great time for the team to learn more about our country and reflect back on history. We all soon realized how blessed we truly are.
After leaving Pearl Harbor, the van ride to our next stop was filled with conversation about World War II. Hearing the different perspectives on the war from players from different countries made the conversation much more interesting. After this time of reflection, we were all ready for some shopping to lighten the mood.
We were all excited when we pulled up to a giant market filled with tons of vendors selling a variety of things. It was time to get a souvenir from Hawaii! I loved all the Hawaiian jewelry and couldn't hold back from getting a few things. Many of the other girls found fun shirts or post cards, and a few even tried a variety of island fruit. We all had a great time at the market and spent the car ride back to the hotel showing each other our purchases.
When we arrived back at the hotel it was time to start preparing for our game against Detroit. We soon loaded back into the buses and were off for the field. Today's locker room fun was full of solos from Maggie Brown singing Sugarland, Skylar Chew singing One Direction, and Jasmine Moses singing Mariah Carey. The team laughed and cheered as they sang their hearts out.
The team was in good spirits after the game and went out for Cold Stone to celebrate the improvement we made in Hawaii. It was a nice way to treat ourselves after all the traveling and hard work we put in the past two days. All in All, it was a great third day on the island, and we are all ready to enjoy our last day tomorrow.
Blog Entry #2 (Friday) - A Little Sightseeing and a Big Game
Photos from Day 2
Today was our first full day in Hawaii, and it was filled with excitement. We started the morning off with a fun kick-around in a nearby park. As we walked to and from practice, we were able to explore what surrounds our hotel. A really nice mall with plenty of shopping and restaurants fill the area, along with the ocean where people were enjoying the surf. It was a great way to start the morning, and begin to get a taste of what Hawaii is like.
Later in the morning we all piled in our vans and took off for North Shore. We had a great time in the car ride staring out the windows at all the interesting plants and trees. We also spent the time getting to know our teammates better and telling funny stories. When we arrived at North Shore we were able to walk the beautiful beach. The sand was so soft, and the ocean was so blue. We didn't get the chance to get in the water today, but we hope we'll get to on Sunday!
On the way back to the hotel from North Shore we stopped at the Dole Plantation known for their "Pineapple Experience." We had the opportunity see the pineapple garden, taste coconut peanut butter and pineapple ice cream. We all loved the pineapple ice cream, and wished we had it back in Muncie.
Following the Dole Plantation it was time to begin to prepare for the game. We had a great day so far, but now it was time to take care of business. We had some pre-game fun in the locker room where Maimee Morris, Emma Crenshaw, and Pavla Benyrova showed off their ballroom dancing skills. We were all so excited to play a night game under lights, and we truly enjoyed ourselves out on the field. A hard-fought game ended in a 1-1 draw.
Following the game we had dinner at the field with the Hawaiian team we had just played. We learned a little more about the Hawaiian culture as we spoke with the girls, and compared our college experiences. It was a great second day in Hawaii, and we can't wait to see what tomorrow will bring!
Blog Entry #1 (Thursday) - Arrival in Hawaii
Photos from Day 1
Today was a long but exciting first day. We began our journey to Hawaii at 3:30 in the morning in Muncie, and arrived in Honolulu at 2:00 in the afternoon Hawaii time. Although there were many sleepy eyes on the bus, and in the airport, the team was all smiles. Many of us could not hide the excitement of traveling to Hawaii for the first time.
Landing in Hawaii was an exciting moment, and just as many of you would expect, we were all camera-happy. With leis around our necks, palm trees all round, and cameras in hand, we were reading to set out on our Hawaiian adventure.
Today's adventure was short and sweet after a long day of traveling. Our first stop was at the field where we will be taking on the University of Hawaii on Friday night. Next we stopped for dinner near our hotel where everyone was in good spirits. There was a lot of joking and laughing around the dinner table, as we all began to get more comfortable with our environment.
The highlight of today was seeing a beautiful rainbow overlooking the outskirts of the city. We all laughed when someone commented, "Only rainbows are this bright in Hawaii!" Although it's early morning at home, it's bedtime here! We can't wait to see what tomorrow has in store, and we hope to gain another victory for the Cardinals!


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We would like to welcome you to our optometry practice. Our doctors, Dr. John Regner and Dr. Tristan Begotka, provide each patient with quality vision solutions and exceptional customer service.
Our staff is experienced in all areas of vision care, routine care as well as medical eye care. Maintaining healthy eyes requires regular eye exams. We look forward to serving you with the same valued eye care skills and services that our patients have learned to expect from us. The Regner Family has provided quality vision care to the Kenosha area for over 95 years.


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Title: I Can See Tomorrow: A Guide for Living with ...
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Artist: George
Album: Believe
Genre: Rock
4 o'clock in the morning, I'm chilling with some friends
Before the club we're hanging out until this girl walked in
Come on by surprise her when she didn't say hello
Had an attitude, why be so rude I know just what to do
Wanna go outside I pull out and came running
Told the girl don't act this way
I see right through your act
What he did was such a shame
Don't be living with this man
So let it go tonight
I see the beauty within your eyes
So let it go tonight
I never thought that it would be me
How could I be such a fool, oh?
And here I am saying girl I'm sorry
For something I didn't do, this is my point of view
Baby I never meant to fall for her
Lately it's been driving me crazy
Baby, baby, you still and always will be my baby
Oh yeah..
It's 4 o'clock in the morning and it didn't take too long
For the girl to change her tune and now she's singing a different song
She's all up on me, kissing on me, grinding on me
What's a guy to when his brain is all muted
Baby I'm not that guy
I already got that someone in my life
Baby I'm not that guy
I let her in only before a minute girl
She was up in my mind
But it was you I found a start
You'll always have my heart
Say my heart
[Chorus x2]
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A few years ago I was able to visit Santorini. This glorious Greek isle was the perfect back drop to a Mediterranean vacation in 2006. I am planning a Greek adventure again for 2012. I miss the fresh food, the sun, and ouzo. Santorini is known for this magnificent and vibrant blue on top of buildings. Imagine my delight when Kimberly's TranquiliT clothing featured this insane blue called Santorini. I knew I had to have the new longer cardi-wrap in this color. I'm planning lots of color for Spring and Summer. I'm obsessed with everything Santorini blue. On Sunday I heard someone say "I've heard of this thing called Spring. I'm trying to find it." So am I.
The color palette for TraquiliT Spring 2011
Butter London's Blagger Nail Lacquer. This is a must have for my nails.


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This third edition of the most complete and authoritative science reference ever published demands recognition by every physician. More than 2,500 experts, including many Nobel prize winners, contributed to the 15 excellently bound, highly readable volumes which are kept up-to-date by a series of yearbooks. The borders of modern medicine are limitless: molecular biology is now upon us and many articles refer to subjects ranging from high temperature physics to ecology. It is a pleasure to use this encyclopedia to obtain clearly written information outside of one's field of specialization. With over 12,000 photographs and an entire index volume, this work is very easy to utilize. Many articles bear directly on medicine and closely related subjects. It is both a vocation and an avocation to read this work. For example, there are over 110 articles on modern meteorology, over 90 on solid state physics, over 250 on organic chemistry, and
Thank you for submitting a comment on this article. It will be reviewed by JAMA Internal Medicine editors. You will be notified when your comment has been published. Comments should not exceed 500 words of text and 10 references.
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Wii U
Is Zelda:SS really that terrible, or is it an over-exaggeration?
"Master, this enemy has a 95% chance of weakness in the eye location. I suggest attacking it with your Bow." - typical stupid Fi comment.
I hated it. Mainly because of the motion controls. I dislike them a great deal. They did the job, granted. But a basic controller would've been worlds better. Also, I was slightly indignant that I had to upgrade my old motion controls since Nintendo outmoded their hardware. And it was just as tedious and unresponsive as the previous version. So that also played a part.
PsyrenCall posted...Banjo2553 posted...
Yup, when I first saw him I rolled my eyes and said aloud "C'mon Japan not another one of THESE guys" And the fact he actually stands in as TWO dungeon bosses with very little difference (as far as I've gotten) just makes it all worse.
Xcalibur02 4 years ago#64
Admittedly, there are a few Zelda fans that say the game is disappointing, but they still acknowledge that it's a good game. The only people that say it's terrible are trolls that say everything Nintendo does is terrible, or they just really hate motion controls.
Personally, It's my favorite Zelda next to Wind Waker.
Grammar: The difference between knowing your **** and knowing you're ****
PhaseSlaethe 4 years ago#65
It is decent. Around a 7.
Combat was dumbed down from TP, and the motion control gimmick was never necessary to that level.
The story was...par, I guess..for an origin story.
The characters were hit a few times, and miss by a mile. IE, 3-4 were fantastic.
The game progression is the biggest fault, tho.
Remember how in Ocarina, you had to get 3 items to get the Sword?
Well, imagine doing that about 9 times in a row in Skyward Sword.
Get 3 things to unlock the surface world to get 3 more things to unlock more stuff to get 3 more things to go somewhere special to get 3 more things to prove your worth to get 3 more things to get your prize to get 3 more things to go where you need to go.
lostinhellview 4 years ago#66
It's not terrible. But It's length, specifically the dungeons are too long and non linear. No control options hurts imho. A very bland boss with no creativity is fought 3 times. Painfully slow begining. I'd still give it a 90+ though for it's story and look.
ADHDguitar 4 years ago#67
It's a 9/10 at least.
Most, if not all criticisms come from it being different than past games, having motion controls, or being linear.
Still waiting for Diddy Kong Racing 2
the controls will not listen to what you tell them to do 20% of the time,that's not players fault.
and lol a people calling ss unique. giving us the exact same formula with ONE new gimmick on top of it.
it's the same thing tp did as well as ww,ph,and st yet people pretend that only tp did it,because they didn't force the gimmick as mandatory the entire game.
tp=never claimed to be innovative so you shouldn't except it to be innovative
the other 4=claimed to be innovative but aren't
the reason people dislike those games is the gimmicks ruined there experience not that it was different.
smb3 was different from smb but it did so without throwing convention out the window.
I am a furry AND PROUD to admit it.
Also guess what I AM SMASHKING84
Master_M64 4 years ago#69
40Dribylf posted...
From: The_Hyphenator | #008It's a huge exaggeration. It's all part of the Zelda cycle; the new Zelda is always the worst one ever, until the next one is announced, and at that point it becomes a beloved classic. For examples, see Majora's Mask through Twilight Princess.
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"AND LO! Mackenzie Nettles thusly approached!"- CeliaOfTheSky
Ness0123456789 4 years ago#70
I don't find it exaggerated at all, and I sure as hell don't buy into the "Motion Controls are perfect" nonsense either.
The game boasted originally to have 1:1 controls, they are not, despite some magazines (including everyone's favorite sell out Game Informer) claiming otherwise. The dungeons are very short, uninteresting, and simply boring (two of the dungeons could honestly be mistaken for extensions of one another). It also didn't help that two dungeon's bosses were identical to one another, and the constant re-fights of the Imprisoned felt tacked for the sake of prolonging the game.
Skyloft was the only redeeming factor of the game's over-world. Hyrule it's self was a linear, hand holding mess that offered very little exploration or discovery, and the back tracking was absolutely ridiculous, far worst than what was seen in Twilight Princess.
The game's only redeeming factor was it's emphasis on story telling over anything else, and that many of the characters weren't as painfully two-dimensional as the games prior to Twilight Princess.
The game is a mediocre adventure game at best, and an absolutely terrible Zelda game at worst.
Each person might see a rose with a different shade of red, but the fact that we can all agree on is beauty -- that is a miracle.
-Michea, FFXI
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Make This for Brunch
Photograph by Noel Barnhurst
When's the last time you saw the words "Korean" and "tagliatelle" together in the same menu? We're guessing never. Take a trip around the world this Sunday (well, not really that far–the "tagliatelle" here is just thin strips of zucchini) with this week's brunch menu.
You can even do it…wait for it…in your PJs.
The menu does require some planning: the steak needs to marinate overnight. But for a trip around the world in your slippers, it's a small price to pay.
Finish off your grand journey with these coffee crunch bars; they'll take care of any lingering jet lag. —Brette Warshaw
The Menu:
Zucchini "Tagliatelle" with Mint, Cucumber, and Lemon


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I'd suggest turning up your logging levels to the maximum level (5) on
the clients, and creating all the necessary directories under
/usr/openv/netbackup/logs/ especially bprd and bpbkar. This will tell
you what the last file that was attempted to be backed up was, which
could be helpful.
Also, check for bpbkar processes that may be hung and/or still running.
If there are, which I'm guessing there might be, do a truss -p on the
pid and see what they are doing.
My most recent run in with this problem was due to volmgt being
confused and the /vol directory being a bad state. An ls -l on root
would hang trying to stat that directory. Simply doing a umount -f /vol
and restarting volmgt corrected the issue.
solarisgeek wrote:
> Dear,
> We have a problem with 2 servers running Solaris 10 and Netbackup.
> When we try to backup our client we always get errorstatus 24 after
> backing up 7GB or 34GB or 67GB or random GB of data.(it's gives a
> broken pipe after a while.)
> Networksettings are equal and it's fixed 1000Mbps full duplex on the
> switch and servers.
> Can someone gives us tips or solutions?
> Thx
> Greetings,
> Tijs


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Surprise! The Alternative Minimum Tax (AMT) may catch millions more taxpayers in 2012.
IMG Via Flickr
By: Charles W McGrath Jr CPA, CFP®. | December 1st 2012
If you enjoy this article please support us by "liking" our Facebook page. Thanks!
2012's taxes will be higher if Congress does not change anything. This article will help taxpayers anticipate how their 2012 tax bill will increase because of the Alternative Minimum Tax (AMT).
Calculating an individual's tax liability can be complicated. It gets even more challenging when there are two different methods. Since 1986, US taxpayers have been burdened with paying the higher of two tax calculation results, the regular tax or the AMT. If the current 2012 AMT methods and rates are not changed, as many as 25 to 30 million taxpayers may be subject to increased tax liability due to AMT when preparing their tax returns. The AMT that was designed to require a small number of high income individuals to pay some taxes can now ensnarl many middle income wage and pension income recipients.
Whole chapters in advanced tax textbooks have been written about the AMT. Rather than trying to explain the entire complicated topic, this document will narrow the focus to the AMT exemption amounts. Understanding AMT exemptions will help explain why many more taxpayers could be subject to AMT for 2012. This is the aspect of the AMT that Congress has changed the most during each of the last several years. Often, Congress increases the AMT exemptions late in the tax year. The last "patch" Congress passed expired at the end of 2011. However, since there are several tax issues to resolve this year, it is very possible that Congress will not adjust the 2012 exemption amounts. By not doing anything regarding the AMT exemptions, the federal government can significantly increase revenues generated without increasing tax rates. This is a "back door" way of collecting more federal taxes.
Please note that the 2012 AMT calculation ignores capital gains and dividends. These types of income will continue to be taxed at 15% for the 2012 tax year.
The 2012 regular tax calculation allows taxpayers to subtract $3,800 from their adjusted gross income (AGI) for each exemption claimed on the tax return. (For example, a taxpayer is entitled to an exemption for themselves, their spouse and each qualified dependent that the taxpayer supports.) If a taxpayer is married and has two children, their tax return would subtract $15,200 ($3,800 times 4) from their AGI for the regular tax calculation. (If that taxpayer is in the 33% tax bracket, these exemptions can reduce the amount of regular taxes owed by over $5,000.) Once a taxpayer's adjusted gross income exceeds a certain level, the AMT calculation eliminates these individual exemption amounts and instructs taxpayers to subtract the following amounts (no matter how many exemptions the taxpayer is claiming) potentially increasing the federal taxes owed by this taxpayer almost $1,000 for each qualified dependent claimed on the tax return:
The 2012 AMT exemption amounts are significantly lower than 2011's and returns them to the amounts used for the 1998 tax year.
Furthermore, when alternative minimum taxable income (AMTI) exceeds the following amounts the AMT exemptions are reduced by 25% of the excess:
For a married couple filing a 2012 joint return, the $45,000 AMT exemption could drop to zero when their alternative minimum taxable income exceeds $330,000. This phase out means that for every $10,000 increase in their AMTI over $150,000, they lose $2,500 of the exemption amount and increase their taxes by approximately an additional $650 because of the 26% AMT tax rate.
Consider an example of a married couple with an oversimplified tax situation such that they have no dependents, capital gains or dividends. They have adjusted gross income equal to $165,000 and deductions approximating $12,000 for charitable contributions and state taxes. After considering their regular tax exemptions ($3,800 times 2), their regular tax will be approximately $29,000. Continuing this scenario, their AMTI equals $160,000 ($165,000 minus $5,000 of their charitable donations) so their 2012 exemption amount, because of the AMT phase out calculation explained in the table above, will be $42,500 ($45,000 minus 25% of $10,000). This would mean that $117,500 ($160,000 minus $42,500) of their income will be subject to the 26% AMT rate so their total AMT could equal $30,550 ($117,500 times 26%) (28% for the AMTI amount greater than $175,000). Since the AMT is greater than the regular tax in this scenario, this couple would pay an additional $1,657 for AMT. If another couple had more dependents or larger AMT adjustments and preferences (like state and local taxes paid), the difference between the regular tax and the AMT could increase by even larger amounts.
Although there are many complicated aspects of the AMT calculation, the most common occurrences that can cause AMT issues are when a taxpayer has large deductions for state and local taxes, large miscellaneous deductions (the kind that appears near the bottom of the Schedule A) and many dependents (usually children) who are claimed as exemptions. Unfortunately, since the AMT is close to a "flat rate" tax system with limited deductions, there are few tax planning steps a taxpayer can do to avoid the AMT surprise. If Congress does not increase the AMT exemption amount for 2012, many more taxpayers need to recognize that their 2012 tax bill may be higher than 2011's even with the same level of income and deductions. Many of these taxpayers may not have withheld enough during the year from pay and retirement checks to cover their 2012 taxes and will be surprised by the large remaining balance owed in April 2013. Please do not shoot the messenger when the tax preparer conveys the bad news after using professional software to complete the complicated calculations.
This article was prepared by Charles W McGrath Jr CPA, CFP®. You can contact him for further information at email@example.com or 480-951-1040.
If you enjoy this article please support us by "liking" our Facebook page. Thanks!


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A 6" x 6" promotional cleaning cloth that is great for cleaning sunglasses or computer screens.
Make the clean choice with this custom microfiber cleaning cloth featuring your full color imprint edge to edge.
Two-tone contour shape printed drawstring backpack made with microfiber and mesh.
This microfiber promotional golf towel safely cleans delicate screen and electronics.
Promote your optometry business in a creative way with a promotional eyeglass cleaning cloth.
MicroBuff Mini promotional screen cleaner is perfect for cleaning your glasses or any of your electronic device screens.
A great logo golf pouch is a perfect promotional giveaway for your next corporate golf outing.
A promotional cell phone holder that contains a microfiber screen cleaning cloth.


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The Intersection
Mike Maneval - Editor
Mike Maneval, Sun-Gazette business editor and past winner of a William Randolph Hearst Foundation award, previously wrote for publications in Mountain Home, Idaho, and, here in Pennsylvania, in State College, Ridgway, St. Marys, and Kane. His blog, The Intersection, is dedicated to topics on which business and the economy meet politics.
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• The mechanisms of ischemia-reperfusion injury in skeletal muscle remain controversial. Some investigators have demonstrated that heparin can ameliorate ischemic injury to heart, brain, and renal tissue. We investigated the ability of heparin sodium to decrease ischemia-reperfusion injury in an isolated gracilis muscle model in ten anesthetized mongrel dogs. One gracilis muscle was perfused normally while the contralateral muscle was subjected to six hours of ischemia followed by one hour of reperfusion. Five dogs were given a preischemic bolus of heparin sodium (200 U/kg, intravenously followed by a continuous infusion (15 U/kg/h, intravenously), and five control dogs received no heparin. Quantitation of skeletal muscle ischemia-reperfusion injury was determined by histochemical staining with triphenyl tetrazolium-chloride and computerized planimetry of the infarct size. Results from the ischemic muscle demonstrate a significant beneficial effect of heparinization. The nonheparinized dogs had a 72%±5% infarct size, which was significantly reduced to 24%±8% in the heparinized dogs. The mechanism of this protective effect may be due to heparin's anticoagulant, antiplatelet, or anti-inflammatory action.
(Arch Surg 1988;123:470-472)
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On Tap Today: Hollywood elbows its way back
Who'd a-thunk Hollywood still had the juice? But the mainstream film industry did indeed seize this year, striking back at the box office against the relentless trendiness of indie films. Learn more as Movie Critic tells us what movies he put on his 2012 Top 10 List – and why -- in Friday's Weekend Cue.
Dining Critic Carol Deptolla has a "Best" list of her own. She gives us a roundup of "Best New Restaurants of 2012." Among them: Braise, c.1880 and Odd Duck . Find out what other new dining places made it to the top this year, and why you should check them all out. »Read Full Blog Post
Olly Murs brings a mixed bag of tricks to The Rave
Olly Murs has been touted as the U.K.'s answer to Bruno Mars ahead of his new campaign to break out stateside.
Thing is, we already have a Bruno Mars. »Read Full Article(1)


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Wisdom From the Guru of Yoo-Hoo
Yogi Berra has always impressed us as a true wise man, fielding life's curveballs and tossing back pearls of wisdom like "The future ain't what it used to be," "When you come to a fork in the road, take it," "I really didn't say everything I said," and "We're lost, but we're making good time!" So we were glad to see the fall issue of Tricycle: The Buddhist Review's feature "The Koans of Yogi Berra." Finally, the sayings of the Sage Behind the Plate would receive the thoughtful commentary they merit.
What a disappointment to find writer Brad Stroup's regrettably glib approach to Yogi's aphorisms. We realized that if the Great Number Eight were ever to be accorded due respect, it would be up to us to get the proverbial ball rolling. We grabbed our copy of The Yogi Book (Workman, $7.95) and searched for an enlightened one to illuminate Yogi's wisdom before all the world.
Our quest, like one of Berra's 358 career homers, took us on a spiritual base path that led back home to New York, where Robert A. F. Tenzin Thurman, longtime student of His Holiness the Dalai Lama, is the Jay Tsong Khapa professor of Indo-Tibetan Buddhist Studies at Columbia University. Thurman, whose name recalls another great Yankee catcher, has also played behind the plate. His commentary follows.
Yogi is clearly living in the moment. He comes up with gems of humor, creative non sequiturs that free the mind in a Zen koan-like way. His sayings are priceless. He reminds me of the Mullah Nasr ud Din, the Sufi sage who also lives in a world of humor.
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"Take the fork in the road!"--this really frees you from a tiresome journey.
He didn't say everything he said? Of course not, because, as a liberated soul, he let himself go into the changing flow of the river of the self. He didn't try to fixate himself in a rigid mold; therefore, the gems of "mind-turning phrases" came into being all on their own.
That the future ain't what it used to be couldn't express better how our last few generations have let down their posterity, letting the planet slide into radical imbalance, burning up the resources as if there were no tomorrow for anyone else! Those people in charge are indeed lost, and yet they are making frighteningly good time, since they cannot understand the Yogi!
Acolytes will be pleased to know that a Yogi Berra Museum is scheduled to open this fall in New Jersey. Adjacent to Yogi Berra Stadium at Montclair State University, the shrine charts auspicious moments in Berra's life, including his boyhood in St. Louis (where he was first recognized as a Yogi) and his fateful journey to the East.
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Developers of DTC Genetic Testing Are...
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At first, a decrease in the DO level below the specified set point for all Dasgip vessels during the initial days of the production step was observed. It turned out that the choice of sparger entailed a different maximum gassing rate from manufacturing scale to maintain the DO to set point. The reason for this behavior is the difference between the size of the bubbles produced by the different spargers, which results in diverse bubble residence times.
Since the open steel pipe as well as the L-sparger produce bigger bubbles their gassing rates has to be increased by nearly a factor of six, leading to a final 0.083 vvm, instead of the 0.015 vvm used for the 12 kL bioreactor. The gassing of the vessels using the sintered microsparger, however, could be kept the same. This sparger generates small bubbles transferring oxygen more efficiently to the culture and providing better dissolved oxygen control at low cell density.
For both cultures run with the L-sparger and the open steel pipe (default), cells grew to a maximum viable cell density on day 9, and then entered a stationary growth phase followed by a moderate death phase. These trends are comparable to those observed at manufacturing scale (Figure 3).
The Dasgip system set up with a sintered microsparger exhibited comparable growth until day 5; a more dramatic decrease of viable cell density was subsequently observed. Those findings are caused by the sintered microsparger design: small bubbles provide a greater interfacial area than larger bubbles, leading to a higher oxygen transfer rate. However, smaller bubbles also carry more cells to the top gas-liquid interfacial area, where cell damage occurs due to bubble bursting.
At inoculation, all sparger configurations present lower viabilities than at manufacturing scale (Figure 3). This is due to medium-exchange operations, which are not performed at manufacturing scale.
From day 3 on, the viabilities are comparable between manufacturing scale and all sparger configurations in the Dasgip system, up until day 9 when the loss of viability is more pronounced in the Dasgip system. Here the set up with the L-sparger showed the best results, with viabilities closer to manufacturing scale.
Figure 3 demonstrates that in both Dasgip systems set up with the L-sparger and the open steel pipe, titers are comparable to those obtained at manufacturing scale with slightly higher titers using the L-sparger configuration. Titers are, however, significantly lower with the sintered microsparger configuration due to the lower cell growth and viability.
Finally the product quality attributes were measured only for the Dasgip systems run with the tube open steel pipe and the L-sparger. All product quality attributes were comparable to those obtained at manufacturing scale and within specifications.
A scale-down model is considered comparable to manufacturing scale when all critical quality attributes—growth, productivity, and product quality—are comparable between scales.
As such, the Dasgip system proved to be a viable alternative to the use of 2 L glass bioreactors as a reliable scale-down model. The L-sparger configuration provided more comparable growth, productivity, and product quality data at manufacturing scale than the default sparger and the sintered microsparger. Its volumetric gas flow rate was higher than at manufacturing scale due to a lower bubble residence time in the system. However, this difference had no impact on process performance.
From an economic standpoint, the Dasgip system proved to be a cost- and time-effective model. The preparation time for the Dasgip vessels is approximately one-third of the time needed to set up a 2 L bioreactor. Moreover, only half the amount of raw materials is needed for the Dasgip system due to its smaller working volume compared to the 2 L glass bioreactor.
Elodie De Roo ([email protected]) is manager of small-scale fermentation, Julia Tisserand is an engineer, Christelle Laroche is cell culture manager, and Eva Carolina Hofmann is biology laboratory assistant all in the production enabling, biotech manufacturing department at Hoffman-La Roche.
Elodie De Roo ([email protected]) is manager of small-scale fermentation, Julia Tisserand is an engineer, Christelle Laroche is cell culture manager, and Eva Carolina Hofmann is biology laboratory assistant all in the production enabling, biotech manufacturing department at Hoffman-La Roche.
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A paralyzed man who was once a political prisoner in Cuba is now back home with his family thanks to the Catholic Church.
Ariel Sigler, 44, became a paraplegic in a Cuban prison while serving a 25 year sentence for treason.
The government released him June 12 in a rare humanitarian gesture negotiated by the Catholic Church.
Sigler was arrested in 2003 along with 74 other Cuban activists and journalists during a crackdown on political dissidents.
"It was when the entire world, some people who had a blindfold on their eyes, were able to remove it and see that here in Cuba there are violations of human rights," Sigler said. "There have been violations of human rights and there will continue to be violations of human rights as long as the Castros remain in power."
His release came after Catholic Cardinal Jaime Ortega asked Cuban President Raul Castro to liberate some of the island's 180 political prisoners.
The government agreed to release Sigler and transferred 12 others to prisons closer to their homes so families could better provide for their needs.
Berta Soler's husband was one of the relocated political prisoners. She's a leader of the "Ladies in White" protest movement.
"I thought that he would be the last one to be transferred," she said. "Well, God placed His all-powerful hand and now they are transferring him."
There's still a long way to go with Cuba's zero tolerance for political dissent -- something Sigler knows well.
"I will continue to fight for the freedom of my brothers who are in prison so they can rejoin their families, which is where they should be," Sigler said.
The Cuban Catholic Church will help in the fight as well, hoping to play a vital role in humanitarian negotiations that will reunite more families.
Former U.S. State Department official Roger Noriega told CBN News Cuba's Catholic community is vital to tackling human rights issues there.
"You will really need that sort of moral foundation in the transition period so you can leach out the toxins of distrust and self-loathing and hate that Communist regime uses to hold on to power," he said. "So I think that the Catholic Church has an indispensable role to play in this country."
Noriega added that the Catholic Church should be more vocal in condemning the Cuban government.
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[QUOTE=RitaRose;967176]My brother has a saying: Life is so much better now that I no longer give a shit.
Sounds really horrible until you realize there's some truth to it.
At my work, we had a few guys that hauled ass to get their routes done super-human fast so they'd look like the model employees. The rest of us hustled, but we didn't literally run our routes, we just walked really fast. These guys never got promotions. All they got was more and more work added to the routes (so more and more stress added to their work days) and stuck in the same position with the rest of us waiting to get laid off.
I'm not saying you shouldn't try and do a good job. That's just having a good work ethic. But I do think there's this idea that, if we work our asses off doing stuff we hate, there will be some kind of reward at the end, and that's not always true. You have to find your reward in daily life.[/QUOTE]
I know what you are talking about. Employers tend to give those who produce more work.
In my field, there was no place to move up, so coworkers were cutting about keeping themselves in the spotlight as big "personalities" or tooting their own horns over being the best. I didn't do it, and they think you're incompetent if you don't blow a loud horn.
In my field, if you don't do the work, no matter how much, you're out. They can bring someone else in, because the field is so saturated. Believe me, there are people who will work for almost nothing to get experience.
I agree about not expecting any big reward for working hard. In this economy, the only reward is having a job, period. Having an income one can get by on.
I agree about trying to find rewards in life, I think truly, our reward is just ecking out a living. Just having a roof over our heads, food on the table, a warm place to sleep. Those are our rewards.


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To the editor:
Lewistown Police Department would like to take this opportunity to thank the community for its overwhelming support for our "Fill a Cruiser" to fight hunger. This event was co-sponsored by the Lewistown Giant store on Dec. 20, 2013.
The event was the inspiration of Sgt. Michael Hoskavich and benefited Mother Hubbard's Cupboard, a local food bank located atat 21 South Main St. in Lewistown.
The idea to help fight hunger in our community was greatly helped when, a few days before our event, the fourth and fifth grade Lewistown Intermediate Students held a food drive and donated over 2,000 food items - an outstanding job!
On the day of the event, people throughout the community donated food to our officers who stood by in the parking lot of the Giant store. A huge "thank you" also goes to the Giant store employees who made a large donation.
It was because of the support of the community and the LIS students that this event was such a success and resulted in the delivery of much needed food items to the food bank at Mother Hubbard's Cupboard.
William F. Herkert Jr.
Chief, Lewistown Police
Deborah Bargo
Mayor of Lewistown


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Field Hockey Faces Northwestern Tuesday
MUNCIE, Ind. - The Ball State field hockey team will be back in action at the BSU Turf Field on Tuesday, Sept. 10 for a 3 p.m. matchup with the Northwestern Wildcats. Live stats and a live broadcast by Sports Link Radio on WCRD will be available at ballstatesports.com.
Ball State (2-2) is coming off a split weekend having dropped a 1-0 contest to Robert Morris before picking up a 2-1 win over Colgate on Sunday. Junior Tarel Teach netted two goals for the Cardinals against the Raiders en route to the victory.
Teach and freshman Lexi Kavanaugh have both scored two goals for the Cardinals so far this season. Sophomore goalkeeper Shelby Henley has one shutout under her belt and a 2.50 goals against average that includes 41 saves.
SCOUTING NORTHWESTERN: Northwestern is on a four-game winning streak having most recently picked up wins over No. 16 Boston University (4-1) and Miami (Ohio) (3-0). Carolin Troncelliti and Nikki Parsley are the top goal scorers for Northwestern with four and three so far this season. Goalkeeper Maddy Carpenter has a 1.27 goals against average with 16 saves in 2013.
SERIES HISTORY: Northwestern holds a 17-7-2 record in the all-time series that dates back to the 1981 season. The last time the Cardinals took a win over the Wildcats in Muncie was on Sept. 18, 2002 when Ball State earned a 2-1 victory.
You can follow the team on Twitter at @BallStateFH or on Facebook by liking "Ball State Field Hockey". Ballstatesports.com is the official site of Ball State Athletics.


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I've tried. Others have tried harder than me. FWIW, I enjoyed my runs a lot more even if I ate just a few carbs (less than 10g) before a run. Raisins worked for me.
I know that long distance running isn't exactly extolled around here as an activity in which Grok would have engaged, but...
I'd really like to run the LA Marathon in the spring and I'd like to do it without increasing my carb intake; so...
Has anybody engaged in long-distance running while in ketosis?
I've tried. Others have tried harder than me. FWIW, I enjoyed my runs a lot more even if I ate just a few carbs (less than 10g) before a run. Raisins worked for me.
I never know if I'm in ketosis or not, but I've done a lot of distance running on a very low carb diet and have never felt negative effects. Granted, a majority of my running was easy training runs or ultra events where you're not burning a lot of glycogen anyway. Did a marathon on low carb by marathoner standards, but nowhere near what I'm at now. Good luck, let us know how it goes!
I raced ATB distance events (30, 50 and 75 milers, 3 to 7 hour races) on zero carb this past summer. Did fine, as good as I ever do, but no bonk or cramps. Never trained for the events, I figure the races themselves are bad enough.
I will be playing around with running some longer distances also as I venture into this PB diet/ lifestyle. I am coming from eating a lot of raw foods so I have some distances on basically all fruits and veggies and was amazed at how good I felt. You may need to plan on some fruit post run. I usually do a green smoothie with protein powder, greens and some fruit. I have amazing muscle recovery on that.
The way I discovered this site was after a comment that Lance Armstrong's strength coach made about his diet. Peter does some 3-4 hr rides with Lance. He said he eats Paleo but has carbs before and after endurance training. My guess is you will have to play around with fruit, sweet potatoes and that sort of thing to up the distance.