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I have been getting told by many people that CareCredit is not really the way to go to help pay for the procedure I want (which is rhinoplasty and considering chin implant due to a doctor's opinion...my chin is too small). I don't know what to do
What Are Your Views on CareCredit? Is It Wise to Use CareCredit to Help with Payments?
Doctor Answers 14
Plastic Surgery Financing
Hello and thank you for the question.
There are several options for cosmetic surgery financing, including CareCredit and GlamourCredit, among others. Each firm offers specials and incentives, some of which can be very attractive at 0% interest for a fixed period. As some of my colleagues have pointed out, reading the "fine print" would serve you well, and finance charges can be considerable under certain circumstances and may change over time.
Best of luck,
Glenn Vallecillos, M.D., F.A.C.S.
Care Credit is fine, but please remember: Those who understand interest, obtain it, those who don't pay it! Be wise my friend.
CareCredit Financing for Plastic Surgery
Dear KatrinaAnn,
CareCredit is a very popular method for financing plastic surgery and can help make plastic surgery more affordable and accessible. Like any method of financing, you should understand your payment obligations and be sure that both the surgery and financial responsibilities are good choices for you.
Warmest wishes,
Larry Fan, MD
You might also like...
Care Credit
Care Credit is an excellent method for many patients to help finance their plastic surgery. Care Credit is typically very helpful and they try to taylor plans to meet most patients needs. If it is unnecessary for you to finance (ie, you have the cash, or already have credit available) then paying the promotional APR may not be worth it for you. For most of my patient who inquire about financing, Care Credit is a convienint option that still allows them to keep the credit they already have open for other expenses.
Financing Plastic Surgery
Hi there-
CareCredit is one of the better know options for financing your surgery. As with all financing/loan options, the devil can sometimes be in the details. Be sure the interest rate and term of the loan are acceptable and favorable for you, and you should have a good experience.
Web reference: http://www.DrArmandoSoto.com
CareCredit is the leading option for patient financing. The program is not for all, but the interest free programs are attractive. While the interest rates for the longer term programs are high, the rates are more reasonable than most other companies.
Web reference: http://www.drkrisreddy.com/West_Palm_Beach_Rhinoplasty.html
Care credit
Care credit is one option for financing your surgical procedure. Like any type of financing there are fairly high interest rates attached to it.
Is CareCredit a good way to pay for cosmetic surgery?
It really depends on the plan offered by your physician. We for instance offer a six month interest-free plan. As long as you pay it off in 6 months, it is a great deal. We also offer a layaway plan.
Financing cosmetic surgery
Care Credit is frequently used for financing cosmetic surgery. Overall, it is a bit more expensive because of interest charges, but it is a reasonable way to go to achieve a permanent improvement in one's appearance.
Good luck!
Web reference: http://www.facialinstitute.com
CareCredit to Pay for Rhinoplasty Surgery
If possible, it is always better to pay for your surgery up front but CareCredit is a reasonable option if you must borrow the funds. Many patients have successfully used this program without problems.
These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.


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The World deserves a Church that reveals the
Glory of Jesus
KT's Bible College
Do you desire to go deeper with God?
In the last 30 years, here at the International Bible Institute of London, we have dedicated our lives to the pursuit of God, and the training and equipping of His people. Each day we find that there is more of God to explore, greater depths of revelation, and more grace to enjoy! The grace of God radically transforms us through encounters with His word and power, leading us away from the external conformity of the law to the place of profound inward transformation through the goodness of God.
If your journey with Christ has led you to a point where your spirit cries out "I must know more of Jesus!" why not join us in your pursuit? We are here to empower you to shine for Jesus in your world!
We are a Bible College within a vibrant, multi-ethnic community called Kensington Temple in the heart of London, the world city – all aligned to the singular pursuit of growing to be more like Jesus. We dream of a world with disciples of Jesus at every level of society, revealing His glory! We encourage you to prayerfully consider giving a year to God to take your place in His plan.
Colin and Amanda Dye
Unique Opportunity – R.T. Kendall Guest Lecturer for 2017
I am so honoured that Colin Dye, Kensington Temple and IBIOL have invited us back to spend almost six months in London – end of January to early July 2017. I especially look forward to working with Principal Gabriel Chan during this time.
What I like most about IBIOL is their commitment to Holy Scripture and what it teaches. Their primary concern is the honour and glory of God. From this emerges their resolve to maintain equal emphasis on the Word and the Spirit – a combination so rare and so needed these days.
I hope to see both old friends and new as we enter into what promises to be a most exciting time together. Pray for us that we will ever be faithful to our calling, and that our word and testimony will bring great pleasure and praise to God.
R. T. Kendall
Your options to go deeper with Christ

subset: commoncrawl


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Tenth Annual Terrorism Conference
Save the Date! Wednesday, December 14th
The National Press ClubGrand Ballroom 529 14th St. NW, 13th FloorWashington, DC 20045
About the Event:
The Jamestown...
The newly-promoted Chinese leaders who ascended to power at the 18th Party Congress in November must address a number of important foreign policy issues, one of the most important of which is what role China should play on the global stage as its power and influence continue to grow. Part of the debate centers on the extent to which a stronger China should be prepared to accept a greater level of responsibility globally. Indeed, considerable discussion of this issue has taken place since then-Deputy Secretary of State Robert Zoellick's September 2005 "responsible stakeholder" speech, but Chinese analysts continue to debate how much responsibility China should accept. Even as Chinese officials continue to grapple with international calls to assume greater responsibilities, and domestic pressure to more assertively defend China's interests abroad, they are attempting to cultivate a positive image of China as a "responsible great power" (fu zeren daguo) [1].
China's "Developing Country Reality"
Beijing's September 2011 white paper China's Peaceful Development argues that China is "actively living up to international responsibility." The document suggests that the level of responsibility China should be expected to shoulder globally remains limited by its focus on domestic challenges and its current stage of development:
"For China, the most populous developing country, to run itself well is the most important fulfillment of its international responsibility. As a responsible member of the international community, China abides by international law and the generally recognized principles governing international relations, and eagerly fulfills its international responsibility. China has actively participated in reforming international systems, formulating international rules and addressing global issues. It supports the development of other developing countries, and works to safeguard world peace and stability. As countries vary in national conditions and are in different stages of development, they should match responsibility with rights in accordance with their national strength. They should play a constructive role by fulfilling their due international responsibility in accordance with their own capability and on the basis of aligning their own interests with the common interests of mankind."
Nonetheless, the document also suggests China's willingness to bear international responsibility will increase along with its growing power. Specifically, it states "For its part, China will assume more international responsibility as its comprehensive strength increases" [2].
In line with the section on China's international responsibilities in the development white paper, some Chinese observers contend the appropriate level of responsibility should be closely linked to China's status as a country that still faces many daunting challenges. Because China is still a developing country in some important respects, they contend, domestic and international observers should not have unrealistic expectations. For example, according to a June 2010 China Daily article, "There is ample evidence to show that China is playing an active role in global matters…On the other hand, national strength and international status should determine the international responsibilities China should accept. Given China's developing country reality and the current West-dominated world order, it is far-fetched, if not ill-timed, to demand that the country undertake duties that are beyond its prowess" (China Daily, June 17, 2010).
Similarly, Ministry of Foreign Affairs official Le Yuecheng argued in May that, although China is now the world's second largest economy, it is not yet the second strongest nation. Le acknowledges that some observers criticize China as a "selective stakeholder," one that "speaks of itself as an 'elephant' or as an 'ant' as needed." They want to see China become a "comprehensive stakeholder" instead. Furthermore, notwithstanding all that China has achieved as a result of more than 30 years of reform and opening, the country still has numerous shortcomings. Consequently, Le argues—even though China has increasingly behaved as a "responsible member and international stakeholder" as reflected by its response to the international financial crisis, diplomatic role in regional security issues, and participation in anti-piracy operations in recent years—"China is both unwilling and unable to assume more international obligations and play the role of a major power" [3].
A Larger Role on the World Stage
Some Chinese scholars encourage a greater global role, and a few argue in favor of heavier responsibilities. For example, some recommend that Beijing provide more global "public goods." Within this context, some Chinese scholars have focused on the global commons—to include the high seas, international air space, outer space and cyberspace—as an area of growing interests and greater responsibility for China. For example, according to Zhang Ming, a researcher with the Shanghai Academy of Social Sciences, "along with China's increasing national strength, its international standing has been in constant ascendance" Furthermore, as China's international standing and influence have continuously expanded, its interests increasingly have become intertwined with the security of the "global commons." Consequently, Zhang writes "As a responsible rising power, China needs to determine how best to position itself in the governance of the global commons." To this end, Zhang recommends that China should not only participate in discussions about these issues, but also actively engage in maintaining the security of the global commons. Zhang highlights China's counter-piracy operations in the Gulf of Aden as an example of China taking action to address shared security problems. Such participation is required to "protect [China's] expanding national interests, particularly overseas interests" [4].
China's increasing interconnectedness with the world means promoting the security of the global commons is essential if China is to "promote development, maintain national security, and prosper culturally." It is also necessary to cultivate China's desired image as "a responsible great power on the international stage." In addition to protecting its own security, economic and cultural interests and burnishing its international image, Zhang argues, "as a responsible great power, China should actively provide regional and global public goods and make its due contribution toward maintaining the peace and openness of the 'global commons" [5].
Some other Chinese scholars have made similar recommendations. For example, Wang Yizhou, a professor and administrator in the School of International Studies at Beijing University, suggests China should provide more "public goods" and international aid (International Herald Leader, December 20, 2011). Another Beijing-based scholar, Li Yonghui, argues China should move beyond a narrow-minded view of the world and "shoulder historic responsibilities" [6]. In Li's view, "China is rising to become a major power in the world, and therefore it should have a great power mentality and great power diplomacy." In particular, Li writes, China should supply more "public goods" to peripheral countries in order to strengthen its regional diplomacy. Similarly, Wu Xinbo, Deputy Director of Fudan University's Center for American Studies, argues it is in China's interest to play a responsible role as a major power and provide more "public goods" to regional countries. Offering such countries economic and security benefits will reduce their reliance on the United States, Wu contends, thus contributing to the development of a "more equal" order in the Asia-Pacific region (Global Times, July 29, 2011).
Yet, even scholars and analysts who advocate shouldering greater international responsibility suggest China will face daunting challenges as it assumes a larger role in world affairs. For example, according to Zhang, China faces challenges stemming from the attitude of the United States and other Western countries. Even as they expect China to make a greater contribution toward safeguarding the global commons, they also are "concerned that their own preeminence will be challenged" and thus use their discourse about China, diplomatic pressure and their military power to guard against and constrain China. For example, Zhang asserts, they frame the discourse about the global commons in ways that portray China alternately as a "stakeholder and collaborator" and as a "potential challenger, competitor, trouble maker or even opponent," while coordinating diplomatically and developing new concepts to counter perceived threats from China. . China should "be calm and composed, and respond appropriately," Zhang writes [7].
Still another challenge for China is that its capabilities, though growing, remain limited in some areas, such as military capability. Chinese analysts assert that China's military requires greater situational awareness and improvements in its capabilities for force projection as well as humanitarian aid and disaster relief missions. For example, according to Zhang, China needs to improve its space and communications infrastructure, build a more powerful air force and strengthen its naval capabilities [8].
The Responsibility Trap?
Still other Chinese observers are deeply wary of accepting greater international responsibility. Some even suggest Western calls for China to shoulder heavier responsibilities are a trap that Beijing must avoid. According to a March 2009 People's Daily article by Li Hongmei, "Since it was initiated by the former U.S. Secretary of State Robert Zoellick, the theory of 'China's responsibility' has been exaggerated and embroidered in recent years. Especially in times of economic slowdown, it has become a term much sought after by the Western world. It seems that they intentionally coined the term in a bid to make it well-tailored to their special needs later." Moreover, according to Li:
"…the concept of 'great powers' responsibility' is defined by the Western world completely on the conditions of satisfying its own needs and interests. Simply put, whether to be responsible for the world, from the Western perspectives, is literally evaluated by how much responsibility you have assumed for the West. Some Western countries are desperately pressing China to actively shoulder more responsibility as a great power, but it is manifested that they are eager to capitalize on China's strength in order to shake off their own troubles" (People's Daily, March 23, 2009).
Some Chinese commentators have been especially suspicious of Western demands for China to accept greater responsibility for global economic and environmental problems. According to another article: "Some Western countries have been throwing out various 'China responsibility' theories after the global financial crisis. These responsibilities form a system that seems to grant China a responsibility to save the world." Furthermore, the article warns "These theories are fabricated on purpose by some western countries. They have been exaggerating China's strengths and influences in a bid to let China shoulder more 'world-level obligations and responsibilities' and also make China increase its 'contributions' to tackle the global economic downturn. The objective is to slow down and check China's development" (Xinhua, August 19, 2010). Similarly, Huo Jianguo, President of the International Economic and Trade Research Institute of the Ministry of Commerce, has charged that Western countries intend to distract attention from their own problems, force China to adjust its policies in accordance with their demands and "burden China with 'responsibilities.'" The ultimate goal, Huo asserts, is to "serve the Western strategy of curbing China's development" (Beijing Review, September 2, 2010). Other observers have echoed this theme. For example, an August 2010 op-ed asserted the underlying motivation of demands for China to shoulder greater responsibility "lies in some Western countries' attempt to distract world attention from facts and burden Beijing with more responsibilities that it should not and could not shoulder. In other words, some Western countries are too eager to shirk their responsibilities and pass on their burden to China" (China Daily, August 18, 2010).
Chinese scholars and analysts, like their counterparts in the United States and many other countries, are still wrestling with some of the key issues surrounding China's emergence as a great power, including what role China should play on the global stage. One complicating factor is that Beijing must balance calls for China to do more with the risk that actually doing more would intensify concerns about China's growing power. Beijing could face accusations of "free riding" if it fails to take greater responsibility for international problems, but a more activist role could stoke fears that China intends to project power regionally—and perhaps even globally—in ways that could undermine the security or challenge the interests of the United States and its allies. Consequently, it should not be surprising that Chinese scholars continue to discuss and debate the contradictions and challenges inherent in China's emergence as a great power, including the question of how much international responsibility China has an interest in accepting and the capacity to handle.


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Oakland Raiders coach Hue Jackson predicts breakout seasons for two of his young defensive players—fourth-year strong safety Tyvon Branch and third-year end Matt Shaughnessy—in 2011, the San Francisco Chronicle reported.
A year ago, Branch produced 104 tackles, four sacks, one forced fumble and one interception in his second year as a full-time starter in Oakland. Branch has proved himself to be a force against the run but still needs to polish his game against the pass. Jackson says Branch is an underrated player who deserves recognition for his relentless style.
"This guy plays football, in my opinion, the way it's meant to be played," Jackson told the Chronicle. "He plays as well and as hard as anybody I've ever seen play the game."
Last season, Shaughnessy had seven sacks and two forced fumbles while starting half the Raiders' games. He teams with Lamarr Houston to give Oakland a pair of quality young ends.
"Matt Shaughnessy is a tremendous player," Jackson said.
Jackson also has high hopes for second-year kick returner/wideout Jacoby Ford, who returned three kickoffs for touchdowns and tacked on two receiving TDs in 2010.
Ford is expected to also return punts this season, which should make the Raiders more dangerous on special teams.
"Obviously, he still needs to continue to play at a high, consistent level, but I think this young man's ceiling is so high that it's going to be tremendous," Jackson said. Jackson thinks all three eventually could be regarded as top-100 players leaguewide.


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Rihanna, Kesha and Nicki Minaj hit the 2011 Billboard Music Awards red carpet
Plus: Fergie, Taylor Swift, Nas, 50 Cent, Kylie Minogue and more
Next gallery »Best and Worst of the Billboard Music Awards: Britney, Rihanna, Nicki
« Previous galleryBritney Spears, Jennifer Lopez, Ke$ha rock KIIS FM's Wango Tango
Kesha aka Ke$ha aka Disneyland princess?
Kesha (Ke$ha) continues to astound with her fashion choices as whe walks the red carpet of the 2011 Billboard Music Awards.
Photo Credit: AP Photo/Dan Steinberg


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Top Definition
Trinidadian acronym for "What D Ass", Or in english, "What the ass"
Breds, take in this big cockroach I find.
автор: addirealest 19 июля 2014
Trending Now
Can you define these popular missing words?
Wall(Facebook) display of affection.
I hate when Adam & Olvia WDA every fucking day.
автор: Swag1 17 мая 2011
water drinkers anoynamiss later changed to wsa -weed smokers anoynamiss, a very homo-sexual group that they thought was cool
wow get out of town wda kids,
автор: typhy 3 мая 2007


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Ironbridge Gorge Museum
The Ironbridge Gorge Museums are a collection of 10 museums located in Ironbridge Gorge, near Telford. Indoor and outdoor museums make it a great day out for people of all ages.
RAF Cosford Museum
The Royal Air Force Museum at Cosford houses one of the largest aviation collections in the United Kingdom. Over 60 historic aircraft are displayed in three wartime hangars on an active airfield. The collection spans nearly 80 years of aviation history.
Visiting Shropshire Museums, Stay at Hadley Park House Hotel
Much Wenlock Museum
A fascinating insight into how Much Wenlock declares itself as the birthplace of the Modern Olympic Games and the story of how it's creator Dr. William Penny Brookes devised the games to help stop people from drinking!
Acton Scott Museum
Acton Scott Historic Working Farm near Church Stretton demonstrates life on a Shropshire upland farm at the turn of the last century and has recently been shown on the BBC's Victorian Farm.
Shrewsbury Castle & Shropshire Regimental Museum
The oldest parts of the Castle were built between 1066 and 1074. In the 18th Century the interior was remodelled as a private house by Thomas Telford. Shrewsbury Castle is home to the Shropshire Regimental Museum with uniforms, medals, weapons and equipment from the 18th century to present day.
Wedgwood Visitor Centre
Set in over 240 acres, the Wedgwood Visitor Centre tells the life of pioneering potter Josiah Wedgwood. Interactive visitor centre and impressive museum showcasing a phenomenal collection of Wedgwood memorabilia.
Black Country Living Museum
Black Country Living Museum is the largest open-air museum bringing the story of the Black Country to life with a village and residents to chat to, trams to ride, stories to hear.
Thinktank Birmingham Science Museum
Ten themed galleries of immense fun! The most modern of science museums complete with planetarium!


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I've heard the horror stories already. ĀBut I'm having trouble just getting info on the average recovery after vaginal delivery. ĀI'm considering a VBAC because C-section recovery is so so difficult, especially with a toddler running around. ĀAm I wrong to think that recovery is easier with a vaginal birth?
C-section mom wondering about Vaginal Delivery recovery
Comments (7)
I had a VBAC and the recovery was so much easier it is A SMART thing to do. I was able to play with my toddler a few days after birth. I think it was well worth it and I hope to have another vaginal delivery in Jan.
Kaitlyn Snow Jan 22, 2008 ( due Jan 25th) Via c/s
Savannah Ryan Dec 29th 2010 (due: Jan 06th) VBAC
Chandler O'neill EDD Jan 7th 2012
I had a very quick recovery with my vaginal delivery.┬Ā I have never had a csection, so I can't compare, but I was up and around that same day.┬Ā I did have a small tear which caused me some trouble for awhile, but it didn't restrict my movement or any activities outside the bedroom.
Kit Monkey Girl 9-27-08 Silver Boobies (.)(.) Monster Boy 1-17-12 Gold Boobies(.)(.) Munchkin Girl 10-29-13 Silver Boobies (.)(.)
I had a c-section with my first and a VBAC with my second. I was very concered about recovery time, becuase I thought that the c-section recovery was pretty quick. After my VBAC I was up and going in no time. (My son was 9lb1oz and no tearing which I thought was amazing!) I loved not worrying about the incision and pain pills. I am driving a 1/2 hour to see a doctor out of town who does VBAC's becuase I really want to do one again. Because of policy changes in the last 9 years since my son was born, its pretty difficult to do one, but I really believe its worth it. They will try and scare you with the risks, but the risks of major abdominal surgery are more scary they just tend to gloss over them!┬Ā
I've only had a vaginal delivery but I recovered pretty quickly. Of course there was soreness and there's the inevitable fear of pooping ( TMI I know but it was a BIG thing for me! lol). The worst that I had was shortness of breath upon standing for the first two days and I think it only lasted that long because I had to a chace a nurse down a corridor because she had my son and refused to push me in a wheel chair.( I was a home birth which is very looked down upon by most medical personel. LO was fine though!)
Doing my best with two little terroists.
My first was vaginal and the most painful part for me after the birth was the episiotomy recovery it was worse than my csection.┬Ā my csection i was up and ready to go by the next day.┬Ā Im having anther csection so im nervous if it will be a harder recovery the second time around.
Raekwon 12-2-2000 Stillborn at 39 weeks
Victoria 6-17-2009
Vivienne 11-28-11 IUGR, Premmie 34.5 weeks 3.3lbs


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Top Definition
(adj.) a disgruntled worker who always talks about burning down/blowing up his or her place of employment, but never actually does.
Right before Melvin got fired, he was the blaziest dude in the company.
di Rollie Hatch 27 gennaio 2005
Trending Now
Can you define these popular missing words?
A combination of blazed and lazy. Usually occurs after imbibing wheelchair dope.
"Duuude that was a good hit but now I'm all blazy."
di 80122 03 dicembre 2007
The feeling of being lazy after a long day of blazing.
Damn, i'm feeling so blazy right now... can you light the next one?
di JuanDizzle 24 novembre 2011
Extremely bored but too lazy to do anything.
Justin: Im so bored but too lazy to get up and do something.
Lindsey: Me too. I'm feeling blazy today.
Justin: I'm blazing so hard.
Lindsey: Me too. I'm feeling blazy today.
Justin: I'm blazing so hard.
di Laura Shipman 27 gennaio 2013
marijuana cigars, blunts.
"Yo, who's rollin' those blazies?!"
di MODACIOUS! 06 luglio 2008
The condition of behavior in which someone, usually of African descent, is crazy.
"You're black! You're crazy! You're Blazy!"
di Sexcellent 09 febbraio 2007


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China to regularize volunteer service
05 December 2004
Beijing: The Chinese government will soon take measures to regularize volunteer service, authorities said on the occasion of International Volunteer Day. A national committee for volunteers will be established to overlook volunteers' activities across the country and provide guidance for them.
The committee is also expected to set up branches at various levels in China, including city, district and community levels.
In addition, organizers of volunteer activities will be trained regularly to improve work proficiency.
At present, there are more than 80 million registered volunteers in China.
From: China View


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Not that I am a number watcher.. BUT…
I wanted to say thank you to all of you that read and share the Scoutmaster Minute.
The numbers do not mean a thing as I do this out of a love for Scouting, as you can see there are no adds that shoot money my way…
But it does go to show that we in the Scouting community do love and care for Scouting.
As of today I noticed that the Scoutmaster minute crossed the 30,000 mark.
So to celebrate.. I am off to our Troops Court of Honor!
Looking at the Pie Chart… its also cool how International the Scoutmaster Minute has become.
Just in the last week we have had 149 visitors from the US, 7 from the UK, 5 from Belgium, 2 from Germany, 2 from Canada, and 1 from the Philippines.
Thanks again everyone and Have a Great Scouting Day!
One thought on "30,000"
I'm totally a number watcher. When I post something I think will elicit interest I watch to see if it gets clicked. If not, I wonder why. If it does I get a little thrill. It's a sad comment on my personality, but there I am. My first bloggerversary is coming up and I've been collecting some statistics which is why I found your post to be timely. I know I'm always fascinated when someone in a non-English speaking country comes to my blog. Cool beans.


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Virginia Tech Athletics Department
Merryman Athletic Center
25 Beamer Way
Blacksburg, VA 24061
Responsibilities: Bennett meets with student-athletes on an individual basis for personal counseling and to discuss the mental aspects of their life as it relates to their sports. He also works on team building, communication and performance enhancement. Bennett has taught and supervised pre-doctoral level interns.
Joined VT Athletics Staff: 2000 (full time since 2007).
At Virginia Tech: Bennett began working at Virginia Tech in 1995 at the Cook Counseling Center. Now, as the sport psychologist, he also serves on the committees for nutrition, performance and substance abuse; and the planning committee for the "Summit for Student-Athlete Success" events. He also works with various teams in the area of performance enhancement.
Education: Centre (Ky.) College, 1981 (B.A. in English), where he played baseball; University of Kentucky, 1988 (master's in rehabilitation counseling); University of Kentucky, 1995 (doctorate in counseling psychology).
Of Note: Bennett is licensed as a clinical psychologist and has additional training in sport psychology. He is certified as a sport psychology consultant by the Association of Applied Sport Psychology and is a member of Division 47 (exercise and sport psychology) of the American Psychology Association.
Personal: Bennett lives in Blacksburg and enjoys playing golf and basketball, as well as hiking and skiing, in his spare time.


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Biogram – Serotonin: Fertilizer For Your Patience & "Herbicide" For Your Liver
Serotonin: Fertilizer For Your Patience & "Herbicide" For Your Liver
Seeing the beauty in biology is easy. The earth's canvass is painted with life…from the microscopic and abstract to the grand and inspiring. We are inundated with amazing images of life, some obvious, many obscure.
|Fig. 1 - Dorsal Raphe and Prefrontal Cortex
Like I mentioned before, the dorsal raphe is connected to several regions in the brain, one of which happens to be our decision-making center: the prefrontal cortex (Fig. 1). After shutting down the dorsal raphe, serotonergic signaling to the prefrontal cortex was reduced, and the rats were less patient.
The body's first priority is to seal the wound as quickly as possible, via a process called "fibrogenesis". The body's repairmen (platelets and special cells called fibroblasts) are recruited to the scene of the crime and start producing tiny fibers of collagen. These fibers fill the wound, like plaster in a wall, and create a scar across the damaged area.
Turns out that platelets use serotonin as a messenger to coordinate their efforts with fibroblasts.
Can't Wait
1the wonderful images…Serotonin (5-HT) neurons expressing Green Fluorescent Protein (GFP) under the transcriptional control of the Pet1 gene promoter in the dorsal raphe. Pet1 is found exclusively in serotonergic neurons. Left panel: green/blue is staining of GFP, pink is staining for serotonin. Lower panel: GFP staining alone. Immmunohistochemistry. 10x magnification. [© Tessa Hirschfeld-Stoler and Columbia University. All Rights Reserved. Do not use or reproduce.]
2When the researchers turned off the serotonin neurons…Accomplished by infusing a 5-HT1A receptor agonist into the dorsal raphe with reverse dialysis. Activating the 5-HT1A receptor, one of 14 mammalian receptors, inhibits of adenylyl cyclase activity and opens K+ channels, which results in neuronal hyperpolarization and decreased neurotransmission.
Miyazaki KW, Miyazaki K, & Doya K (2012). Activation of dorsal raphe serotonin neurons is necessary for waiting for delayed rewards. The Journal of neuroscience : the official journal of the Society for Neuroscience, 32 (31), 10451-7 PMID: 22855794
Miyazaki K, Miyazaki KW, & Doya K (2012). The role of serotonin in the regulation of patience and impulsivity. Molecular neurobiology, 45 (2), 213-24 PMID: 22262065


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Welcome to ANSIRH
Welcome to ANSIRH
ANSIRH on Twitter
Banner photos: All-Options Pregnancy Resource Center by Backline Bloomington; Dr. Dan Grossman speaking at the North American Forum on Family Planning © Michael Rubottom Photography.
Research category photos: Abortion photo © Can Stock Photo Inc. / Mark Adams, Rocketclips. Contraception photo © Cindy Chew for ANSIRH. Culture image part of an infographic designed for ANSIRH by Jessica Harrington, with art direction by Kate Giambrone and Julianna Johnson. International photo courtesy Stew and Vee Carrington via Creative Commons license. Policy photo courtesy of Heather Ault (modified and cropped). Turnaway photo © Jana Carrey for ANSIRH.


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We are pleased to announce the availability of the phpBB SEO Premod 3.0.9 package, Freezing Fan edition.
This release update the premod to phpBB3.0.9 and the phpBB SEO mod rewrites to the last version ( 0.6.8 ).
The premod as well includes updated versions of the zero duplicate mod, no duplicate mod, Dynamic meta tag, Related topics and GYM sitemaps. All these are soon to be separately released.
This version, among other things and bug fixes, implement a simple yet manual way to easily handle forum without id redirections and adds related topic support for postgres.
Demo : http://demo.phpbb-seo.net/
New in this version :
- All mods Updated to comply with phpBB 3.0.9.
- GYM Sitemaps & RSS 2.0.3:
- Added : image size to few more images
- Added : Get no errors in style sheets when no language files are available (user's fault) and display a BIG red message
- Fixed: the damned coma breaking xhtml validation
- Fixed: pagination string for when custom values are used in GYM HTML
- Fixed: ssl test breaking standalone usage
- Utlimate SEO URL 0.6.8 :
- Added : empty test in page_header to help reducing dependencies (stk)
- Added : Extend pagination rewriting to urls with no ending slash (example.com/location?start=xx vs example.com/location/pagexx.html)
- Added : Allow empty suffix for topic url pagination
- Added : Enhance viewonline tracking
- Added : Use relative and unrewritten url in S_MOD_ACTION redirect param to fix what looks like a mod_security issue
- Added : Implement a convenient way to allow the zero duplicate to properly redirect an updated forum url without id Look in phpbb_seo/includes/setup_phpbb_seo.php for more details about the usage
- Fixed : Fix js pagination for non rewritten links
- Fixed : Handle spaces in topic pagination (highlights and keywords param could contain some)
- Fixed : Use [OR] instead of the implicit [AND] for the optimization RewriteCond's in the .htaccess, since obviously, a request cannot match a directory AND a file at the same time.
- Fixed : Properly handle topic_url when set even if sql_rewrite is not activated
- Zero duplicate 0.6.8 :
- Fixed : Fix canonical element not displayed without the no dupe
- No duplicate 0.6.6 :
- Fixed : Last topic link could use wrong forum with virtual folders and sql rewriting off
- Meta tags 0.4.4 :
- Added : Add empty test in page_header to help reducing dependencies (stk)
- Fixed : explain in acp stating the exact opposite of what it should
- Fixed : Allow a bit more length for settings in acp
- Related Topics 0.2.4 :
- Added : Add ability to exclude forums by id (seo_related::forum_exclude = array(2,8,98 ...))
- Fixed : LIKE query for postgres (using ILIKE). Other dbms, except mysql are yet untested, concerned users are welcome to report on the matter.
Minimum Requirements
phpBB3 has a few requirements which must be met before you are able to install and use it.
- A webserver or web hosting account running on any major Operating System with support for PHP
- A SQL database system, one of:
- MySQL 3.23 or above (MySQLi supported)
- PostgreSQL 7.3+
- SQLite 2.8.2+
- Firebird 2.1+
- MS SQL Server 2000 or above (directly or via ODBC)
- Oracle
- PHP 4.3.3+ (>=4.3.3, >4.4.x, >5.x.x, >6.0-dev (compatible)) with support for the database you intend to use.
- getimagesize() function need to be enabled
- These optional presence of the following modules within PHP will provide access to additional features, but they are not required.
- zlib Compression support
- Remote FTP support
- XML support
- Imagemagick support
- GD Support
The mod_rewrite Apache module will be necessary to use url rewriting. It is though possible to adapt the rewriterules for isap_rewrite on IIS servers (windows).
Security issues found should be reported to the phpBB.com security tracker in the usual way.
Available packages
- If you experience problems with the automatic update (white screens, timeouts, etc.) we recommend using the "changed files only" method for updating.
- Full Package
Contains entire phpBB SEO premod source English and French language files.
- Changed Files Only
Contains only those files changed from previous versions of the phpBB3 SEO Premod.
- Automatic Update Package
Update package for the automatic updater, containing the changes from previous release to this release.
- Patch Files Package :
Contains patch compatible patches from previous versions of phpBB3. Mainly intended for advanced users.
With this release, there are four packages available.
Translations Update :
- Both French and English language pack are included by default in the auto update and changed file package.
- In case you are not using the french language pack at all, you can safely ignore updates of the French language files. Leaving it on your ftp and let the updater update it is of course not a problem.
Be sure to take a look at the official phpBB announcement thread to find out more about the phpBB3.0.9 new features and bug fixes included in the phpBB SEO Premod.
Please note for update :
- This update will not change any of your current URL settings
- An .htaccess update is advised to implement the (little) optimizations added (ACP => phpBB SEO .htaccess)
- GYM Sitemap & RSS
- GYM update process is now included in the auto update package and will handle all the required code changes for the premod files, but you WILL have to run the gym_sitemaps/gym_install.php script in update mode after you updated phpBB. If you do not use GYM, it is still wise to keep the file up to date, if you have deleted them, just ignore the GYM file update.
GYM sitemaps and RSS is likely to be updated before the premod, it will be up to you to keep it up to date meanwhile, you can be notified about updates by subscribing to the release thread while logged in : GYM Sitemaps & RSS module
Note :
- The SEO Premod includes a fix in includes/utf/utf_tools.php for a bug that does not affect all installations but can be quite annoying.
This bug was reported, but was not fixed in phpBB 3.0.7, and surprisingly, will not be fixed, since it was turned to "Will not fix" by the phpBB Group.
For more details : http://www.phpbb.com/bugs/phpbb3/ticket ... t_id=52315


text:
Quarintine/Frog land
Active within 2801 Days
Name: Yellow Tang 2
Size/Category 10-Gallon Freshwater
Type: Glass
Shape: Hexagonal
List of Fish:
2 - African Dwarf Frog6 - Platy babies
Lighting: normal
Filtration: 10 gallon Aqua Fin
Invertebrates: two Frogs
Other Accessories: bog wood, plants, stones
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text:
June 21, 2007
Aircraft: N552JB (Blue Jay)
Scheduled Departure: 7:20 PM
Blocked Out: 7:55 PM
Scheduled Arrival: 10:45 PM
Blocked In: 1:49 AM
Load Factor: 90%
Seat 7B
Oh the joy of flying on a thursday night after a long week at work and a storm arriving. I do this flight approx. 5-8 times a year (going DL every once in a while to mix things up) so I am accustomed to the evening departure rush. It really hit me this time though.
After sitting on the Van Wyck for the usual 30 minutes, we arrived at terminal 6 at 5:45. Since they rearranged the check in kiosks and baggage drop I feel that the wait has gotten longer. Kiosk check in took 2 minutes and we waited about 10 for drop our bags off by the counter. After waiting for the wife watching her follow the bags to make sure they went all the way down the conveyor (Ehh, it makes her happy) we went upstairs to head to security. Most people go to the right after check in so we in turn always go to the left. I find this line a little shorter every time, and the fact that we were departing from gate 2 didn't hurt as well. Security took about 5 minutes and we ventured off to Hudson News.
As many know the B6 terminal is old, dirty, and disgusting........guess what? Nothing has changed. Few stores is good and bad. The wife can't spend money, but then she ends up talking to me instead. The new terminal is coming along nicely though and it will be a welcomed addition when it is ready. We ventured to the gate and saw that it was not very crowded which was a bit of a relief. It can sometimes be an adventure to find a seat over there.
Boarding started a little early at 6:40 for passengers with assistance or those who have small children. Only a few of those so they started full boarding a few minutes later. by 6:55 we were on board and our long long long trek to Seattle would begin.
by 7:10 it looked as if passengers had stopped coming in and we would be ready for an on time departure. I was in the middle, my wife with the aisle and a spanish man had the window (he got on, promptly feel asleep and didn't really awake until we landed (I want whatever the hell he took). The first officer came out to give his little speech about a storm moving in, but we should be able to puck back on time and get out ahead of it. By 7:25, the door was closed and I thought we would just sit in line with the heavies going to Europe and be on our way...........well, I was wrong. At 7:35 we were still by the gate. The TVs were going to keep us occupied and the safety check had been completed so thankfully that was out of the way. The captain got on and said they were just loading some last minute bags and it would be 2 more minutes . "Cabin Crew prepare for arrival".....Excuse me flight attendant?? What did you say? Suddenly the door pops open and a gentleman in an orange shirt strolls on. He is nicknamed douche bag #1.
The captain explains that we were waiting for some late arriving passengers to go along with the late arriving bags (Can it be so hard to get your asses to the airport people?????). The captain originally said 4 would be coming but it was only the 1 guy and the door was closed again. "Cabin Crew prepare for departure" A welcomed saying after sitting in a hot plane. The flight attendant notified the us that according to FAA regulations, since a new passenger had come on, we must perform the safety presentation all over again. A moan from the crowd, TVs off and the presentation for the guy in the orange shirt (Who was sitting Bulkhead no less!!!!).
"Cabin Crew Prepare for Arrival"...........NO NO NO......what the hell is this. 7:50 rolls along and the door pops open to let in douche bags 2-4. I guess the captain was right, there were 4 passengers who were late. I only hope they sat next to someone with a cold and are feeling it this morning. Finally at 7:54 the door was closed, "Cabin Crew prepare for Departure" is heard and we can be on our way.......Oh not before the TVs were shut off again because guess what folks? New passengers = safety demonstration for the 3rd friggin time. A groan with a slight hint of "Enough with this crap" could be sensed in the air.
Push back at 7:55 and we sit in the alley for 10 minutes........then we move to an active taxiway right alongside the terminal. The weather is getting bad with lighting and rain about to come by, but I am watching all the arrivals on 31R rolling by. Suddenly the skies open and we are not going anywhere. The signal on the TV is crapping out and it is real dark outside. The pilot gets on to inform us that ATC has closed 4 out of the 5 departure lanes and number 5 looks as if it will be closed soon.............I knew this was a get ready to sit and wait folks. We taxied to an active taxiway between the 22's and we took our place in line and just sat. We sat and waited. You can see the European heavies in one line, the domestic departures in another line, and our line which seemed like a fair mix. At about 8:50 the captain informed us that no one is leaving right now and we will be shutting the engines down to save some fuel. It was cool on board which did make a huge difference.
We were told by the flight attendants that we would be able to move about the cabin and they would be coming around with bottled water. If we had cell phones we would be able to use them. You really get to hear a lot of cursing when a flight is delayed (most by my wife actually.....thats right folks, she is taken) The pilots never ventured out of the cockpit during this time. The announcements were at a minimum from them with most talking from the flight attendants. Most the channels were not working because of the weather but they slowly started to come back every 20 minutes or so.
At one point after sitting there for about an hour the pilot came on to tell us that the eastern departures wold start leaving soon, but we were number 40 out of 80 for departure (Better than being 80 right?)
Finally at 10:45 the engines were powered on and we started our roll to 31L to be number 4 in line. At 111:14 we were on our takeoff roll and on our way. The climb was a little slower than usual but who cares, we were in the air.
The flight was uneventful for the most part. I slept my 45 minutes so I was "refreshed" and thankfully the cabin crew came around often with water and other drinks to keep us hydrated. The path took us along the Canadian border at FL 350 I believe (Don't hold me to that one). At 1:25 AM we started our descent into SEA. It was quite bumpy after a calm flight with a few ooooh's and ahhh's from the queasy passengers. We landed and taxied right over to A10 with no traffic ahead of us. Finally blocking in at 1:49 AM. We strolled out to see the sad and tired faces of the JFK bound passengers who were waiting for the aircraft to turn around. SEA-TAC is a very nice airport but a bit too much walking. Waited for our luggage until 2:25 and were on our way to the "Out-Laws". The inbound journey was finally over.
The Cabin Crew did an outstanding job during the whole wait, coming around to talk to us and keep us updated with what they knew. The cockpit could have been a little more talkative but I guess thats just an Airliners member opinion.
Otherwise, we are heading back on the Sunday red eye....Hopefully on time!


text:
Well guys my last bet was the Humber Perfect game. Wanted to bet washington sunday and it got washed out.. So i'm 8-7 +$700 to start the season. 4-1 my last 5. Today's play is
Milwaukee -200 for $200 listing both Happ and Marcum. GL to everyone
Copyright © 1995-


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The Tigers managed just two hits in the first seven innings and fell behind by seven runs Monday night on the way to a 9-3 loss to the Minnesota Twins.
The top seven hitters in the order for the Tigers went 0-for-18 through the first seven innings. The Tigers trailed 8-1 at that point.
The Tigers rallied for a pair of runs in the eighth inning, but it was too little, too late.
The Tigers have lost three consecutive games and five of their past six.
The Twins had 12 hits in 5 1/3 innings against Tigers starter Anibal Sanchez. The Tigers had five hits in seven-plus innings -- three of them to start the eighth -- against Twins starter Samuel Deduno.
Deduno entered the game with a 1.576 WHIP, but the Tigers went hitless against him in six of the first seven innings.
-- Brennan Boesch drew a walk -- the fourth issued by Deduno -- to lead off the fifth inning. Jhonny Peralta then laced a double to the wall in right-center for the first hit of the game for the Tigers. Boesch scored from first to tie the game at 1-1.
-- Omar Infante followed the double by Peralta with a single to put runners on first and third. But those were the only two hits for the Tigers until the eighth inning.
-- Miguel Cabrera knocked in a run in the eighth on an infield single, and Delmon Young knocked in another with a single to center.
-- The Tigers had a walk, a double and a single to start the fifth inning but came away with just one run. With runners at first and third and a run already in for the Tigers, Austin Jackson struck out for the first out of the inning. Andy Dirks followed with a line drive to second base, and Omar Infante was doubled off first on the play.
-- Darin Mastroianni hit a solo home run with one out in the fifth to give the Twins a 2-1 lead. It was the third home run of the season for Mastroianni.
-- Ryan Doumit blew the game open the rest of the way with a three-run home run off Duane Below in the seventh inning. It was the 14th home run of the season for Doumit and it gave the Twins an 8-1 lead.
-- Sanchez took a ball off the left leg in the first inning on a line drive off the bat of Joe Mauer. Sanchez recovered and threw Mauer out at first. After a visit to the mound by manager Jim Leyland and head athletic trainer Kevin Rand, Sanchez threw a couple practice pitches and remained in the game.
-- Sanchez allowed five runs on 12 hits and one walk in 5 1/3 innings pitched. He struck out three.
-- Download the "Detroit Tigers on MLive app" for your iPhone or Android and follow Chris Iott and James Schmehl on Twitter to keep up with news on the Tigers.


text:
It's exciting isn't it?
I started the year at 270, pissed no clothes would fit, and generally one sluggish, irritable dude. My girlfriend had to worry about my "hungry monster" coming out if I didn't eat at regular intervals.
Flash forward to today. I stepped on the scale and came in just under 240. I can regularly IF for 18 hours and never experience an energy crash. I miss meals and get by just fine. The hungry monster is gone. I stay focused throughout an entire school day, and I don't end up yelling at my students because I'm crashing.
I think this stuff works.
It's exciting isn't it?
Sassy: Revised - my primal log
Good for you, bobbitt81! Keep at it.
Way to go bub.
My whole life, I've felt like an animal......but I've ignored my instincts. I ignored what I really am. That will never happen again.
My blog
A joyful heart is good medicine
He is no fool who gives what he cannot keep to gain what he cannot lose. - Jim Elliot
Mmmmm. Real food is good.
My Journal: http://www.marksdailyapple.com/forum/thread29685.html


text:
Product Information
Peacock And Paisley House Flag
Flags are the greeting card of your home! Proudly display this beautifully crafted fabric flag outdoors to celebrate the season and to show off a bit of your personality. Made from high quality weather resistant materials, this flag can easily be hung from a standard size house flag pole with ease!
- Approximate dimensions are 29" x 43"
- Made out of high quality fabric
- Easily hangs from a standard size house flag pole
- Fade resistant materials
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text:
The 2011 WNBA All-Star game is full of history.
From the location of the game—San Antonio will be hosting it for the first time—to the college, championships and coach familiarity between the starters of the West.
So here is the break down of the Western Conference roster for this year's WNBA All-Star game.


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Miles Austin: Why big contract hasn't changed me
Dallas Cowboys wide receiver Miles Austin was interviewed on KESN-FM radio on Thursday to discuss last Sunday's game against the Texans and teams paying more attention to him. Here are some highlights:
You received your big contract after having a great season last year. Are you a different person now that you've earned some big money?
No, you're going to get the same guy. Nothing really has changed at all; I'm really doing the same things and hanging out. I mean, I got a couple of people asking me for money ever now and again a little bit more than normal but other than that, it's pretty much the same as always.
After the win against the Texans, the players were saying it's because the team finally had a good week of practice. What was different about that week's practice compared to the previous weeks?
I wouldn't say it was majorly different, but we were all focused. We all really focused, everyone was really into their assignments and we took it seriously. I mean, we take all practices seriously but this week, we definitely had a little bit more sense of urgency and it showed in the game: guys were fired up and ready to go.
What did the Texans do to become the first team to hold you in check this season?
I mean, I think they did a great job and they got a great defense. So, I mean, they got guys out there that are working hard and I was out there giving everything I had and sometimes it just is what it is. Sometimes you get the ball a lot in a game, sometimes you don't but anytime you get a win, it's a plus, so I'm glad we got that going.
Have you started to see more double-teams than you saw last year?
It's funny because double coverage is a funny thing because any zone could technically be double coverage because one guy can cover you as you're running up the field and the other guy can guard when you get up the field. So, it depends. I wouldn't really call it double coverage; I mean, they didn't have two guys standing in front of me trying to hit me off the ball every single time. But, they do a good job with their scheme and we have to work out scheme and we have to throw it to guys who are in good positions to make plays and I feel like that's what we did. We're getting the ball to Dez [Bryant], Roy [Williams] made some huge plays for us and Sam [Hurd] made a big catch down there. I felt like everyone, whenever they had an opportunity to do something and make a play, everyone took advantage of it and that's what we need to do more often to win games.
Did wide receivers coach Ray Sherman talk to the receivers about being more physical this year or have you always just been a physical receiver?
I feel like it's already part of our repertoire already. Dez is a big, physical guy. Myself and Roy are big, physical guys, so anytime you got guys in there that are big and physical but then again, we practice it. I mean, we go out there and practice; coach tells us be more physical and we're finishing plays in practice: you catch the ball and keep running. I mean, working on it in practice helps it out so much more in a game because it's natural…you go in a game and you're going to fight and you're going to scrap for those extra yards because you know how much other guys are going to be scrapping for us and we're going to scrap every yard we can for them.
To listen to the interview, click here.


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Fire Down Below
"Get Steven Seagal to emote" -- it sounds like a fixed game in the traveling carnival like the "Ring Toss" or the "Three Balls in the Waterboat." And just like those games, the prizes suck. Be fortunate enough to haphazardly land a ring on a pole and you get a stuffed teddy bear that explodes on contact with a cat claw. Get Steven Seagal to emote and you get the satisfaction of experiencing a miraculous emotional empathy; the kind that can usually only be had in such venues as bowling alleys and monster truck-a-thons.
Seagal is perhaps fortunate that expectations of his performance have sunk to such an unbelievable low. During the course of the film he actually manages to grin and kiss Sarah Kellogg (Marg Helgenberger) prompting "oohs" and "aahs" from a stunned audience. However, such feats as catching rattlesnakes in midair and beating the crap out of people manage to elicit little more than a snicker. Of course the inhuman robot can catch snakes and kick ass, but smile and kiss a girl? Unprecedented! What's next? Seagal acknowledging his inner child? The next time you step over that blind paraplegic epileptic AIDS victim on the sidewalk, look twice -- it may be Seagal preparing for his next role.
Steven shows up in a small Kentucky town as E.P.A. Marshal Jack Taggart to find the source of some chemical dumping. Seagal, always the modest one, works undercover as a Christ-like religious carpenter, bringing the message of good deeds and environmental safety to the town. Thanks to the advantage of having soft piano music accompany his every romantic overture, he quickly woos Sarah, the town outcast, while beating the crap out of every chemical company bad guy who tries to tell him to get back in his truck and get out of town.
The ass-kicking to developmental scene ratio is way too low in this film. In other words, for every scene in which the audience has to endure Seagal trying to feign human emotion, there should be several scenes in which Seagal beats the crap out of at least twenty-five idiots who always insist on charging him one-by-one.
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wow. what a great movie this
wow. what a great movie this was. i just hated how he always stood with his hands folded on his belly. that got on my nerves.
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Might be the greatest opening lines in Crank history.
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A luxurious jacket in burnt-orange Adobe features a dramatic die cut window which is accentuated with brilliant copper foil. When opened, the folder reveals the details of your upcoming event printed inside on an understated Earth tan layer. When closed, the Star of David design serves to frame your child's name which is again seen along with your personalized information inside.
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DEEP ELLUM — Anyone who had seen Spector 45 play live will tell you: They were a force. And though the greaser-punk band ended tragically with the suicides of frontman Frank "Frankie 45" Campagna and bassist Adam Carter in 2011, its legacy of loud-and-fast living will continue with the new documentary film 45by local filmmaker Jonathan Buchner. The project reached full funding Monday via Kickstarter.
With the initial $9,345 goal now surpassed, the documentary is set through post-production. Now Buchner, who cut his teeth in film school at UNT, has turned its focus toward a "stretch goal" of an additional $2,336 to support a local screening.
Buchner moved to Deep Ellum from Denton about three months after Carter's suicide in March 2011. Excited to integrate into the community, he frequented local establishments where he began to notice a common thread. Almost everywhere he looked, whether on streetlamps or in shop windows, there were stickers with a heart encircling the number 45.
"One day I asked a friend what the deal was, and he told me the whole story," Buchner said. "As a filmmaker, immediately I knew it was a story just waiting to be told."
That story remains essential to Deep Ellum's identity. The neighborhood watched Frankie Campagna grow up as the son of Frank Campagna, Sr. Campagna is best known for his Gypsy Tea Room murals, which he painted on the building's external wall between 1998 and the venue's closing in 2006. His work can be seen all over town, in places like "Welcome to Deep Ellum" mural at the neighborhood's DART station. He is also the driving force behind Kettle Art, which bolstered local painters and which will temporarily close in May in search of a new home.
Rather than pale beneath his father's shadow, Frankie Campagna head-banged his way to local superstardom. A constant face on the line up in local clubs, and as a bartender at the Amsterdam, Campagna followed few rules other than live fast, live hard, and support Deep Ellum arts.
Spector 45 was born while Frankie Campagna was still a teenager attending Booker T. Washington when he co-founded the band with drummer Anthony Delabano. The two played with a number of other musicians throughout the years, but the band's final bassist, Carter, added a signature style that added new elements to Spector 45's sound.
"I talked to a record producer during filming," Buchner said. "He said that there was no doubt Spector 45 was going to get signed. They were on the cusp of absolute wonderment."
On January 1, 2011, news came that Frankie Campagna had died at 24, just hours after a searing performance at the Bone. Many grieved further when his death was ruled a suicide. When news of Carter's suicide followed on March 18, 2011, questions – and few answers – emerged.
Buchner's film hopes to offer a bit of insight, and perhaps a smidgen of closure, in the years following the tragedies.
"Originally, I focused on the end. The why. But, the deeper I delved into it and the more I began to learn about these kids, the more I saw that they were a trip," Buchner said. "They were fun. They did crazy things. It was laughter and fightin' and having a good old time. And, it ended so suddenly. So out of the blue."
That's when it became clear that 45 had to be more than a band biography. Buchner believes it could help bolster awareness for the types of deeply hidden and internal struggles that Campagna and Carter faced. "The 45 Fund is still in its infancy, and the film highlights the concepts of getting help to people and letting them understand that it's out there," Buchner said. "It fights against the idea that punk rockers need to be too proud for help. Or, that reaching out is a weakness."
Buchner hopes that talking about those things – topics like depression and substance abuse that can cause dramatic shifts in otherwise happy lives – will help others understand what transpired and how to prevent similar tragedies.
"The film's most important takeaway is that life is fun. Life is a blast," he said. "And, it doesn't take much to change that. And those changes can cause irreparable damage. It's a story about being careful with your lifestyle."
When tackling such a sensitive subject, relying on those closest to Frankie Campagna and Carter was essential. Buchner's film interviews family members and close friends who knew the pair as a couple of raucous kids in search of big thrills. An integral part of the process were Frank Campagna and Frankie's sister, artist/musician Amber Campagna.
"Frank Sr. is the godfather of Deep Ellum," Buchner said. "We're in contact often, and he is really supportive. He wants to get the story out there so that it doesn't happen to others."
To that end, Buchner submitted the reels to SXSW and the Dallas International Film Festival. While 45 didn't make the cut to screen in Austin, it is as of this writing still on the DIFF roll. Buchner said that all DIFF decisions will be made by March 8.
Buchner has also contacted local vendors to initiate a local screening. With additional Kickstarter funds – open through February 27 – he can ensure that the story reaches more people.
Get ready for some seriously NSFW -- and seriously bad ass -- explicit lyrics via netinsanity on YouTube.
"The outpouring was unbelievable," Buchner said about the initial Kickstarter campaign. "It wasn't funded only by individuals, but also a number of local businesses. Everyone pitched in and came together."
While Spector 45 was known as a true spectacle on stage, for those like Buchner, who first heard of Spector 45 only after the tragedies or through the ubiquitous stickers around town, he says it is never too late to learn about the little piece of Deep Ellum as gritty and loud as the famed neighborhood itself.
"Spector 45 is now a main playlist in my car," Buchner said. "They were, and are, incredible. Just watch the videos and the footage. They'll still blow you away."


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Middleton man killed in crash
A 20-year old Middleton man was killed in a crash in Iowa County this week.
The Iowa County Sheriff's Department says a vehicle driven by Devin Emberson went off County Road "I-D" , went up an embankment and then became airborne for a long distance before rolling over and striking a tree early Tuesday.
Emberson was pinned in his car and pronounced dead at the scene.
Deputies say the vehicle was traveling at a high rate of speed.


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Author Affiliations: Department of Neurology, Nagoya University Graduate School of Medicine (Drs Ohyama, Koike, Iijima, Hashimoto, Tomita, Kawagashira, and Sobue) and Department of Pathology and Laboratory Medicine, Nagoya University Hospital (Drs Satou and Nakamura), Nagoya, Japan.
Importance The newly recognized entity IgG4-related disease (IgG4-RD) is characterized by an elevated IgG4 serum concentration and tissue infiltration by IgG4-positive plasma cells. We describe, for the first time, the clinical features and nerve biopsy findings of a patient with IgG4-RD who presented with neuropathy in the extremities.
Observations A 55-year-old man had histopathologically defined IgG4-RD that manifested as sensory-motor neuropathy. The neuropathic features were multiple mononeuropathies with electrophysiological findings suggestive of axonal neuropathy. Marked thickening with abundant collagen fibers and infiltration of IgG4-positive plasma cells were observed in the epineurium of the biopsied sural nerve. A moderate degree of myelinated fiber loss without evidence of segmental demyelination was present, whereas necrotizing vasculitis was not found. Oral prednisolone therapy ameliorated the neuropathic symptoms.
Conclusions and Relevance This case of IgG4-RD presented as sensory-motor neuropathy with pain and sclerosis of the skin in the extremities. The differential diagnosis of neuropathy should include IgG4-RD.
The newly recognized entity IgG4-related disease (IgG4-RD) is characterized by tissue infiltration by IgG4-positive plasma cells, fibrosis, and elevated serum IgG4 concentrations.1,2 These abnormalities were first reported in patients with autoimmune pancreatitis in 2001.3 Currently, IgG4-RD is known to involve various organs, including the hypophysis, lacrimal and salivary glands, thyroid, bile duct, kidneys, retroperitoneum, and skin.1,2 Therefore, the concept of this disease is expanding and involves a wide range of medical branches.1,2 It is thought that this disease is not as rare as previously considered and that the number of patients diagnosed as having IgG4-RD will increase as it becomes more widely recognized by clinicians.1,2 In the field of neurology, pachymeningitis is known to be related to IgG4-RD,4 but this disease has not been considered in the differential diagnosis of neuropathy.
For the first time to our knowledge, we describe the clinical features of a case of IgG4-related neuropathy that exhibited sensory and motor disturbances in the extremities.
A 55-year-old man had pigmentation and sclerosis of the skin around the left ankle that first presented 20 years ago. When ulcers of the skin occasionally occurred, he was treated with betamethasone. However, the skin change did not disappear and remained around the left ankle. One and a half years ago, the patient was diagnosed as having diabetes and has been receiving oral medication to maintain normal serum glycated hemoglobin values (6.0% [reference range, 4.6%-5.7%; to convert to proportion of total hemoglobin, multiply by 0.01]). Ophthalmologists and nephrologists did not note any diabetic complications. At that time, the skin change spread to the lower left leg under the knee and subsequently to the lower right leg. The patient felt numbness and continuous pain in the lower legs 4 months later. Thereafter, the patient noticed a loss of grasping power in the hands. He was admitted to our hospital as the symptoms gradually worsened.
On admission, body mass index (calculated as weight in kilograms divided by height in meters squared) was 20.2. In both lower legs, pigmentation and sclerosis of the skin with ulcerations and with and without scars were found (Figure, A). The patient was alert and well oriented, and his cranial nerves were intact. He had mild muscular weakness in his distal limbs, and his ability to grasp had decreased (right, 23 kg; left, 16 kg). There was no sign of muscle atrophy. On both sides, the deep tendon reflexes were mildly diminished in the upper and lower extremities. Flexor plantar responses were observed on both sides. Severe spontaneous pain existed in the lower legs. The sensation of pain was moderately diminished in both lower legs, and the sensation of temperature was mildly diminished in the right lower leg. The sensation of vibration was severely diminished in both feet. The sensations of light touch and position had not decreased. The patient could not walk a long distance because of leg pain. Although he had dysesthesia in both hands, objective sensory disturbance in the upper limbs was not detected, except for a mild reduction in vibration sensation.
Figure. Clinical photograph and biopsy findings. A, Skin pigmentation with ulcers. B and C, Skin biopsy findings. Fibrosis and infiltration of inflammatory cells were observed in the subcutaneous tissue in addition to numerous IgG4-positive plasma cells (hematoxylin-eosin [B] and IgG4 immunostain [C], scale bar = 50 μm). D-H, Sural nerve biopsy findings. D and E, Marked thickening with abundant collagen fibers and infiltration of IgG4-positive plasma cells were observed in the epineurium (hematoxylin-eosin [D] and azan [E], scale bar = 500 μm). F, Perineural infiltration of inflammatory cells was observed (hematoxylin-eosin, scale bar = 30 μm). G, More than 10 IgG4-positive plasma cells exist in the epineurium (IgG4 immunostain, scale bar = 30 μm). H, There was a moderate reduction in large and small myelinated fibers (toluidine blue, scale bar = 50 μm).
The IgA, IgE, and IgG levels increased (IgA, 569 mg/dL [reference range, 110-410 mg/dL; to convert to milligrams per liter, multiply by 10]; IgE, 847.2 μg/L [reference range, <484.8 μg/L; to convert to milligrams per liter, multiply by 0.001]; and IgG, 2544 mg/dL [reference range, 870-1700 mg/dL; to convert to grams per liter, multiply by 0.01]). Additionally, the serum IgG4 level was elevated (259 mg/dL [reference range, 5-105 mg/dL; to convert to grams per liter, multiply by 0.01]). A serum autoantibody test was positive for antinuclear antibody (titer, 1:160 [reference range, <1:40]) but negative for anti–SS-A antibodies, anti–SS-B antibodies, antiribonucleoprotein antibodies, anti-DNA antibodies, and anticardiolipin antibodies. The test was also negative for cytoplasmic antineutrophil cytoplasmic autoantibody and myeloperoxidase antineutrophil cytoplasmic autoantibody. The serum vascular endothelial growth factor level was normal, as were results of a cerebrospinal fluid examination. Findings on gallium 67 scintigraphy and on chest and abdomen computed tomographic, positron emission tomographic, and magnetic resonance imaging scans of the cranial, pituitary, and lumbar spinal cord did not show any apparent abnormalities.
Nerve conduction studies showed the existence of sensory-motor neuropathy (Table). Motor conduction velocities in the median, ulnar, and tibial nerves were normal (±2 SDs of controls5). The amplitudes of the compound muscle action potentials were preserved in the median and ulnar nerves but decreased in the tibial nerve. Additionally, the sensory conduction velocities were decreased in the median and ulnar nerves, whereas the sensory nerve action potentials were normal. A sensory nerve action potential was not evoked in the sural nerve.
A skin biopsy of the left lower leg showed marked fibrosis and infiltration of IgG4-positive cells in the subcutaneous tissue (Figure, B and C). There was no evidence of necrotizing vasculitis. The frequency of IgG4-positive cells as a percentage of IgG-positive cells in the skin was approximately 30%.
A sural nerve biopsy revealed marked thickening with abundant collagen fibers and infiltration of IgG4-positive plasma cells in the epineurium (Figure, D and E). Although infiltration of inflammatory cells was abundant in the epineurial perivascular areas, findings suggestive of necrotizing vasculitis such as occlusion of blood vessels or fibrinoid necrosis were not found. Immunohistochemical assessments revealed a mixture of CD20-positive B lymphocytes, CD3-positive T lymphocytes, CD68-positive macrophages, and IgG-positive plasma cells in the perineurium and the epineurial perivascular areas. The CD20-positive B lymphocytes were especially abundant in the epineurial perivascular areas, while they were scarce in the perineurium. There were no inflammatory cells in the endoneurium. Clusters of IgG4-positive plasma cells were observed in the perineural tissue. The number of IgG4-positive plasma cells was higher than 10 per high-power field (Figure, F and G). Moderate decreases in the densities of large and small fibers were observed (Figure, H). A few clusters of myelinated fibers, ie, potentially regenerating fibers, were observed. A teased-fiber study indicated axonal degeneration (11.9%) without evidence of segmental demyelination. Amyloid deposition was not detected with Congo red staining.
Because the patient was diagnosed as having IgG4-RD, he was treated with oral prednisolone therapy (30 mg/d). After starting prednisolone, his symptoms of numbness and continuous pain gradually improved and his grasping power increased in 3 weeks (right, 36 kg; left, 30 kg). He could walk a long distance. Blood tests showed that his IgA and IgG levels became normal after 2 weeks (IgA, 375 mg/dL; IgG, 1443 mg/dL) and his IgG4 level became normal after 3 weeks (IgG4, 102 mg/dL).
The entity of IgG-RD has been reported to involve a variety of organs, and some organ-specific diagnostic criteria for IgG4-RD have been proposed.1,6 However, there is no consensus on the diagnosis for IgG4-related peripheral neuropathy. According to the "Comprehensive Diagnostic Criteria for IgG4-RD, 2011,"6 the following items are necessary for diagnosis: (1) swelling or masses in single or multiple organs; (2) elevated serum IgG4 concentrations (>135 mg/dL); and (3) marked lymphocyte and plasmacyte infiltration with IgG4-positive plasma cells (ratio of IgG4-positive/IgG-positive cells >40% and >10 IgG4-positive plasma cells per high-power field) and fibrosis in a histopathological examination. In our case, swelling of the peripheral nerves, elevated serum IgG4 concentration, and fibrosis with IgG4-positive plasma cell infiltration were identified. Thus, most of the characteristic features of IgG4-RD were present.
Focal ischemia resulting from the occlusion of vessels by infiltrating inflammatory cells or constriction by marked fibrosis could be considered mechanisms of IgG4-related neuropathy. The patient's clinical symptoms showed multiple mononeuropathy patterns, and the findings from the sural nerve biopsy showed axonal neuropathy. These features, in addition to perivascular inflammatory cell infiltration, suggest that vasculitis was the cause of the neuropathy.7 However, there were no findings suggestive of necrotizing vasculitis. Recently, a few reports described intraorbital, trigeminal, and paravertebral nerve involvement.8,9 A pathological assessment revealed that the nerves were surrounded by inflammatory infiltration, including the infiltration of IgG4-positive plasma cells with fibrosis. Therefore, constriction by surrounding tissues was likely in such cases. Future studies are necessary to clarify the pathogenesis of neuropathy in IgG4-RD.
In conclusion, we describe the first case, to our knowledge, of IgG4-related neuropathy, which presented as sensory-motor neuropathy with pain and sclerosis of the skin in the extremities. The histopathological findings of a sural nerve biopsy indicated IgG4-RD, and oral prednisolone therapy was highly effective. The differential diagnosis for the mononeuritis multiplex type of neuropathy should include IgG4-RD.
Correspondence: Gen Sobue, MD, PhD, Department of Neurology, Nagoya University Graduate School of Medicine, 65 Tsurumai-Cho, Showa-Ku, Nagoya, 466-8550, Japan (email@example.com).
Accepted for Publication: August 30, 2012.
Published Online: February 25, 2013. doi:10.1001/jamaneurol.2013.658
Author Contributions:Study concept and design: Ohyama, Koike, Iijima, and Sobue. Acquisition of data: Ohyama, Koike, Iijima, Hashimoto, Tomita, Kawagashira, Satou, Nakamura, and Sobue. Analysis and interpretation of data: Ohyama, Koike, Iijima, and Sobue. Drafting of the manuscript: Ohyama. Critical revision of the manuscript for important intellectual content: Koike, Iijima, Hashimoto, Tomita, Kawagashira, Satou, Nakamura, and Sobue. Administrative, technical, and material support: Ohyama, Koike, Iijima, Hashimoto, Tomita, Kawagashira, Satou, Nakamura, and Sobue.
Conflict of Interest Disclosures: None reported.
Funding/Support: This work was supported by grants from the Ministry of Health, Labor, and Welfare and the Ministry of Education, Culture, Sports, Science, and Technology of Japan.
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So it's now May 24th....and after a few weeks of being almost completely primal (only holdout is soymilk here and there, and some sweetness in the coconut creamer I've been using and some paleo macaroons that are loaded with agave).
I went from 150lbs down to 142!!! Since my Celiac began raging after I had my baby at 39, my weight has only gone up (I was thin my entire life, so this was a totally bizarre development, knew something had gone horribly wrong and it wasn't just "getting older"...I don't buy that). This is first time I've seen the number drop substantially like that.
AND I was eating a good amount of steak (not even super lean, I'm a sucker for a dry aged rib eye!), lots of coconut milk, lots of butter in cooking, lots of olive oil. Even allowing the paleo coconut macaroons. So to be eating really well and have this happen is pretty much proving what I already knew. My body was simply not just "Celiac"....it had put the brakes on ALL GRAINS for me. An acupuncturist had recently confirmed this, they work exclusively with food allergies. She checked me for all grains and found a severe sensitivity to all of them. It took a few months to process that information, but in the end, I see what it means.
Soooooo glad to be on this path! I haven't even kicked the excercise into high gear yet (I have a lot of healing to do....need to boost some energy, build some chi).
One thing I've noticed is that juicing greens is adding to my energy 1000 fold. I know juicing is not paleo or primal, but I have some serious gut damage to deal with, and I wanted to nutrient bomb myself from the get go. I've got a 6yr old boy to chase around after, so cooking 3 meals a day pure paleo was going to be a tough. I'm still usually having protein drinks in am, plus a big juice of one apple, 1 carrot, bunch of kale, bunch of collard, some cabbage, some asparagus, some cucumber, etc. The energy boost from that has almost completely dissipated my desire or need for an am coffee.
I'll probably check in every couple of weeks....


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BoE mulls bonus lock-in for bankers
The Bank of England's Financial Policy Committee, chaired by the Bank's governor Sir Mervyn King, is considering locking in all bonuses paid to banking executives until they leave their firms, according to a source familiar with the situation.
Sources say the proposal is an "evolving view" within the FPC, which has been focusing on remuneration.
According to FPC minutes of a meeting last December, the committee was "concerned" about the timescale of deferred bonuses as "the period over which executives' decisions would have an impact on the bank's performance was typically much longer than the period used to judge management performance as reflected in remuneration".
The proposal harks back to an age in the City when much of the partners' net wealth was directly tied in to the health of their firm.
The Bank of England did not respond to requests for comment.