text:
Want to keep up with local commentary on western Washington County issues? This is the place. Catch up with our weekly roundup of guest columns, editorials, letters to the editor and more, all pertaining to Forest Grove, Cornelius and nearby communities.
* * *
Forest Grove:
Forest Grove: A caring community, for Pete's sake (editorial column)– George Rede, Forest Grove Leader
"More proof that Forest Grove is an unusually tight-knit, caring community? The outpouring of best wishes for Mayor Pete Truax after he crashed his motor scooter on his way home from the Farmers Market two weeks ago." -- Rede
Retired Forest Grove teacher: 'How many can say they 'got it' on the first try?' (guest opinion) – Dorothy Regier, Forest Grove Leader
"It seems to me that learning is the whole purpose of school. In any endeavor in life, very few people are successful on the first attempt. Learning to ride a bicycle is a good example. How many people can say they 'got it' on the first try? School works on this same principle: you keep doing it until you succeed, or 'learn,' whatever you are attempting to achieve." -- Regier
Do military recruiters belong in public schools? Readers say yes and no (your comments) – Forest Grove Leader
Local artist Helvi Smith touched off quite the controversy when she wrote a blog post critical of the practice of allowing military recruiters in public schools.
"Smith shared her views after attending a presentation by Marine recruiters at Gaston High School last week – and the reaction, on oregonlive.com and social media, was strong and swift."
Bicyclist's nightmare evolves into triumph (guest opinion) – Betty Campbell, News-Times
"The day was overcast and there was a chill in the air. Tony didn't have enough bicycle helmets for all the children. When we fell one helmet short, I thought to myself, 'It's a closed trail, I'll be safe,' and passed my helmet to Michaela, Tony's 12-year-old daughter." -- Campbell
Washington County:
Washington County elections: Democracy lags, incumbents rule, stability reigns (editorial) – Hillsboro Argus
Washington County's path forward (editorial) – The Oregonian Editorial Board
7 lessons learned from Oregon primary election (guest opinion) – Jayne Carroll, Hillsboro Argus
Jayne Carroll assertion about vote-by-mail questioned (letter to the editor) -- Jason Cox, My Oregon
Planning to leave Oregon? No way (editorial) – News-Times
* * *


text:
At the Newberry Library, Burkhardt Fellows join a lively community of scholars composed of long- and short-term fellows, local Chicago area scholars, and the Newberry's professional staff. This collegial environment encourages interdisciplinary exchange, deepening and expanding the significance of projects in the humanities and related social sciences.
These fellowships support long-term, unusually ambitious projects in the humanities and related social sciences. The ultimate goal of the project should be a major piece of scholarly work by the applicant. ACLS does not fund creative work (e.g., novels or films), textbooks, straightforward translation, or pedagogical projects.
• Amount: $75,000
• Tenure: one academic year, plus institutional support for an additional period
• DEADLINE: September 26, 2013, 9 p.m. Eastern Daylight Time.
Applications must be submitted through the ACLS Online Fellowship Application system (ofa.acls.org).
For more information on the Newberry collection, see: www.newberry.org/catalogs-and-guides
For more information about the ACLS Burkhardt Fellowship, including application instructions, see: www.acls.org/programs/burkhardt/.

subset: commoncrawl


text:
Thank you for visiting our past auction result archives. If you have an item identical (or similar) to this auction lot, please call, write or contact us to discuss. We will be able to help you.
Lot # 947 (of 1560) < Previous Lot | Next Lot >
1933 Washington Senators Team-Signed Ball
Starting Bid - $200, Sold For - $1,293
Official American League (Harridge) ball signed in blue fountain pen by the following twenty-three members of the American League Champion Washington Senators: Rice, Goslin, Manush (sweet spot), Cronin (Mgr., sweet spot), Berg (sweet spot), Bleuge, Bolton, McColl, Whitehill (on the ball label), Crowder (twice, one is partially on the ball label), Kerr, T. Thomas, Russell, Harris, Burke, Chapman, Myer, Boken, Sewell, Kuhel, Weaver, Schulte, and Altrock (coach). The signatures range from "4" to "7," averaging "5/6." The Senators lost the World Series to the Giants in five games in 1933, but little did anyone realize at the time that it would mark the final World Series appearance for the franchise while in Washington (the Senators moved to Minnesota in 1961). In addition to the four Hall of Fame signatures, this ball is noteworthy for the inclusion of backup catcher Moe Berg's signature. Although he was not a star player, Moe Berg is famous today for his role as a spy during his playing days with the Washington Senators, and after his playing days, throughout World War II. Though rarely mentioned, it is a virtual certainty that he was placed with Washington specifically so he could be close to intelligence agency headquarters, which of course were located in Washington. All of the manufacturer's stampings remain bold and legible, and the ball is in Excellent to Mint condition. LOA from James Spence/JSA. Reserve $200. Estimate $500+. SOLD FOR $1,293
(Click the smaller thumbnails to the left and right (if any) to cycle through each photo in the gallery of images for this lot.)


text:
What is in this article?:
What is umami? It was probably on the tip of your tongue last night, whether you grilled a steak, fixed spaghetti or ordered Chinese take-out. Umami is the taste of protein.
- You can find some great protein-packed beef recipes here.
More About:
Umami creates satiety — the feeling that you've eaten enough and that you've eaten the right things. This feeling of satisfaction can help you better control food proportions.
Nothing new
Like the other four basic tastes, umami is notable because it's an element of what makes food enjoyable, and it's always been there. But unlike the other four tastes, umami is a little more subtle and not as evident to folks in this country.
Kasabian says that's partly because for the last 150 years we have been taught there are only four tastes — sweet, sour, salty and bitter. It's also partly because our diet tends to be heavy with fats, dairy products and flavors that mask the umami effect. But all that doesn't mean the umami isn't registering.
"Once you become conscious of it, it's much easier to start picking up," Zino says, noting that Eastern cultures have a better understanding of the palatability of umami than Western cultures.
Not only do our counterparts in Eastern cultures eat a lighter, more delicate cuisine than ours, they also have been talking about umami for 100 years.
In 1908, Japanese scientist Kikunae Ikeda coined the term umami, which comes from the Japanese word umai, meaning delicious. In his research at Tokyo Imperial University, Kikunae discovered glutamate is the main active ingredient in kombu, and key to its delicious taste. (Kombu is a type of seaweed that's an indispensable part of Japanese cuisine.)
Kikunae went on to patent the manufacture of monosodium glutamate (MSG), which is one of the salt forms of glutamic acid. MSG is commercial flavor enhancer that is widely used in the food industry.
Folks in the U.S. food industry mostly dismissed umami until the late 1990s, when researchers at the University of Miami Medical School isolated separate taste receptor cells in the tongue for detecting umami.
The wine industry was first to respond to this development, Zino says. And the food industry soon followed, led in part by the beef industry, which quickly recognized the importance of umami in recipe and product development.
"The beef industry was really a front runner in discussing umami," he says.


text:
We are working on a contracted book titled The Routledge Handbook of U.S. Diplomatic and Military History since 1865. We have already gathered a number of great contributors for this volume and are seeking additional contributors for the remaining sections.
We see this book being used in upper level or graduate classes on military or diplomatic history, with the potential for individual essays or chapters being used in a wide range of courses.
We are seeking two different types of essays, as noted on the brief outline below-historiography/overview/introductory essays and topical essays within the chapter. Below is the list of essays for which we still need contributors.
These essays are overviews of the period and should include a review of literature. Potential contributors should be Associate of Full Professors, or have an equivalent level of experience:
The US in the First World War & Treaty of Versailles
The Origins and Early Development of the Cold War
Clandestine Operations & Cold War on the Periphery 1953-1983
Post Cold War Conflicts
These essays are topical and may be include new material, or new arguments. Potential contributors should hold Ph.D.s, or have an equivalent level of experience, and have a record of publication:
US Military Planning during the Interwar Period
UN Coalition Warfare during the Korean Conflict
Operation Just Cause
Operation Desert Storm
US Troops in Non-Traditional Roles: Humanitarian and Peacekeeping
Essays will be roughly 4,000 to 5,000 word count and we would like a full rough draft by the August 15.
If you are interested please send an email to both Dr. Christos Frentzos and Dr. Antonio Thompson with your preferred chapter and your c.v.
Antonio Thompson, Ph.D.
Assistant Professor, Austin Peay State University
Dr. Christos Frentzos
Associate Professor, Austin Peay State University


text:
Let's applaud hard-working volunteers by Christopher Cutler
Christopher Cutler, executive director of the Canada-based Volunteer Hamilton attests that volunteering is the lifeblood of the community. Volunteering does not only enable us to assist other people, he writes, it also help us undestand that people are different and express our human values.05 December 2006
Read article
Read article
Volunteers help build a stronger society by Khalid Malik
Efforts of thousands of university graduates in helping China's poorest are being recognized on IVD. Read article
04 December 2006
From: China Daily, China
From: China Daily, China
More about: China MDGs: General
Volunteers maintain professionalism: Volunteering Ireland
Dublin, Ireland: Non-profit organizations rely on volunteers to maintain crucial standards of professionalism and accountability in their work, says head of Volunteering Ireland Stuart Garland in his message for IVD 2006. Read entry
04 December 2006
From: Volunteering Ireland
From: Volunteering Ireland
Célébration des contribution au développement de Burkina Faso á la JIV
Ougadougou, Burkina Faso: Comme chaque année, le Burkina Faso s'apprête à célébrer la Journée internationale des volontaires pour souligner les contributions de volontaires à la paix et au développement. Read article
04 December 2006
More about: Burkina Faso MDGs: General
Bringing joy to tsunami victims in Indonesia
Banda Aceh, Indonesia: More than 100 people, many of them affected by the 2004 tsunami, participated in a 'Volunteer Awareness Campaign' organized by United Nations Volunteers programme in Banda Aceh on 2 December. Read article
04 December 2006
More about: Indonesia
100 million volunteers recognized for successful humanitarian assistance
Geneva, Switzerland: The 100 million Red Cross and Red Crescent volunteers and members around the world are essential to making sure millions of vulnerable people receive appropriate humanitarian assistance, according to the International Federation of Red Cross and Red Crescent Societies statement for International Volunteer Day, 5 December. Read article01 December 2006
Supporting Kenya's vulnerable children by Fatou Diop
Nairobi, Kenya: In Kenya, government agencies and volunteer organizations are joining hands to support children orphaned by HIV/AIDS. Aside from holding a ceremony to commemorate IVD, volunteers from various agencies will also visit orphanages and hold a tree-planting session. Read article01 December 2006
Volunteerism: The backbone of dynamic development
In his IVD 2006 message, UNDP Administrator Kemal Dervis commemorates the spirit of volunteerism and the commitment of individual volunteers giving their expertise to improve the lives of others. Read article
01 December 2006
From: UN Development Programme
From: UN Development Programme
Other languages: en français
Providing free medical consultations in Trinidad & Tobago
Port of Spain, Trinidad & Tobago: To commemorate the International Volunteer Day (IVD) 2006, four medical camps will be organized to promote the concept of "volunteerism for development"on 4-5 December in Port of Spain, San Fernando, Arima and Scarborough. Read article
01 December 2006
More about: Trinidad and Tobago Health
'For the Love of Life' in Viet Nam
Ha Noi, Viet Nam: This year UN agencies, the Hanoi Disabled People's Association and similar organizations will hold an exchange programme called "For the Love of Life" on 3 December at Thong Nhat park in Ha Noi. Read article
From: UN Volunteers Viet Nam
More about: Viet Nam Advocacy People with disabilities


text:
Bug From Hell
is any bug where several hours or more of time is spent by a veteran developer attempting to track-down (and fix) the cause of a software bug. By definition, any bug that takes this long to find is almost always the result of a side-effect of the problematic code (otherwise, the problem would be readily visible via typical debug tools--e.g., stack trace, stepping through code in debug mode, etc). A
is very elusive and is typically cannot be isolated or consistently reproduced.
Hours? Nah, a true BFH is one that takes
to find. (Especially in embedded systems work, when "it's a hardware problem" is always a possibility).
The effects of a
typically appear anywhere except near the problematic code. Such a bug will write to random part of memory, flip bits that aren't detected for a long period of running time, or appear to happen randomly without appearing to have been triggered by anything; or, worse, appear to be affected by the act of observing it (a
overwriting part of the stack frame
writing to a memory location that has been moved or deleted (and is now occupied by a different object)
using an uninitialized variable that ultimately leads to writing to a random memory location
an unforeseen interaction between two threads or processes that only has a very small chance of occurring
thread interaction that won't happen running on a single CPU box, but which manifests on multiple CPUs
assumptions made by developers of one webbrowser that aren't made by any other. (You'll always have a <title> tag when setting the charset.)
Hardware drivers that aren't sufficiently paranoid / robust.
JMPing into an unprotected NULL, or into some other executable gibberish.
returning from a function with an unbalanced stack (primarily when embedding assembly code, for embedded systems).
I've got my own
- Copying database records to an array in memory, where logical FALSEs appear in the middle of said array. No logical fields are part of the record.
C code which depends upon the order of evaluation, left to right or right to left.
x[i] = y[i++];
The example was hidden in a macro and the code worked on one compiler and not on another.
I find it interesting that most all of the examples given can't happen in Java. :)
Of course, you can still get a BFH. Not synchronizing concurrent access to a shared object. Not acquiring all pairs of locks in a deterministic order (can lead to deadlock). Not validating some preconditions. (Say a certain collection is of a type and implementation that tolerates nulls, but this particular one should never be null. Access to it should go through encapsulation, and the accessors should test parameters for null before adding them. One doesn't. Code A inevitably gets written that calls this with a null, which it dutifully stuffs into the collection, which naturally accepts it without question. Hours later, code B happens to draw the null out of the collection and dereferences it. Boom! NPE, with a stack trace pointing far from the real cause of the problem. Fortunately, proper encapsulation makes this not so hard to fix, because adding stuff to the collection is probably done through just one method, with proper factoring. Add the precondition test. Run again -- boom, NPE with a stack trace showing the attempt to insert the problem null. Now look for the cause of this null. Repeat as necessary.)
I have a lovely one,
code which runs when compiled with the optimiser on but not when it is off!! My thoughts are fairly unprintable. Solved - but it was the optimiser which was wrong, making wrong code work. --
Back in my
days, I encountered that on occasion. It was usually the result of exceeding array bounds or using an un-initialised pointer. What was the problem with your code?
The problem was the failure to include
return *this;
in an operator= member of a class. The optimizer supplied my missing intention. All I needed to do was to reach for my copy of
and look at page 41. I now have a better knowledge of my code.
Are you sure the optimizer was wrong? I think you may have just encountered
No, the compiler is bugged. Missing return statement of a non-int type, non-void type function is supposed to be a compile time error.
I now have another one (I do love this page for letting off steam) - I am running some tests on a program which is comparing calculations on the main computer with the same calculations on a GPGPU (
). Yesterday they ran and most cases do today but one set inconsistently returns
where it should return a small number. The detail depends on what has run immediately before. I have now turned the computer off for a break - its not this one where I type onto C2. Time for a rest.
This has turned out to be quite a saga. It is not reproducible except that it goes away with a different choice of BLAS routines. More to come. This is turning into quite a saga. There is in fact more than one problem, which always makes for confusion. One is in an array of data which is acquired and then used. Setting it to zero first makes a difference. Secondly it turns out that
has bugs on the particular CPU in use and needs to be compiled for a different one. Mosts things now work but there are still some unexplained inconsistencies. Work in progress. Sigh. --
I know you guys get tired of hearing this, but in my entire career I have
not once ever
encountered a bug that would have remained hidden from a serious application of formal inspection. I have found bugs that could never have been encountered in execution (my own code has contained such), but never have I run into something that would have survived inspection of either the design or the code.
Testing can only prove the presence of features, not the absence of bugs.
You're a fookin' hero, Marty. Remind me to put you in charge of everything. With such perfect hindsight, I bet you can fix all of yesterday, today.
Well, thanks,
. I would prefer not to be in charge of everything, but if you expect yer tests to bail you out of trouble then I guess I'll have to step up. [Aside, to self] Weenie.
A good one: I was working under HP-UX and was porting
under Solaris. While all programs were tested OK under HP-UX (debug and release) and there was a recurring core dump under Solaris under certain conditions only (second build !). The stack trace was pointing inside the STL in some strange template. After investigating the code and finding nothing, the fact was that Solaris
compiler was generating temporary code from the STL templates instantiation (called template DB) in a hidden directory and was not reinitialized when rebuilding. After deleting the template DB, all was OK. I adapted the make files accordingly.
This bug took me two hours to find and an application team were blocked for more than one week on that problem. --
Mine was 3+ hours when I was using a scripting dialect of Basic that did COM interop with a C dll. Basic has a true value of 1 and C has -1 (both use 0 for false). My basic subroutine of toggling the flag was 1 - result, which works in basic for true/false but not in C.
I don't suppose you could have done actual comparisons to "true" and "false," eh?
[Comparisons to "false" might have helped. But C (pre C99) is allowed to use any non-zero value for true. It doesn't even have to be consistant, so comparisons to "true" are useless.]
Good grief. If a project can't be moved to a compiler created in
this millennium
then I suggest you bail, and post haste. I had one such project back in about 1994 where the product was built on a Latice C compiler from 1988. The multi-megabyte mess couldn't compile under a modern compiler because of thousands of various coding standards violations. After spending a couple of weeks trying to get the code cleaned up sufficiently to compile under Borland I gave up. Oh, well. Luckily, they dumped me soon thereafter. Good riddance to bad rubbish.
If a tool prevents you from using what you know to be good practice and forces you into a compromising position with respect to code robustness or even correctness then the tool needs to go. If you can't convince the client (or your boss) of that then you need to go. Otherwise, there is a gotcha awaiting you down the road, and no amount of "I told you so" will get you out of that bear trap once you've stepped in it.
{Amen to that!}
[I agree with the part about ditching tools that get in the way. I disagree with the part about when the compiler was created. In 2005, we were still supporting an application written in a variant of BASIC from the late 70s. It met the client's needs and wasn't any harder to maintain than the applications we supported written for more modern languages.]
//Indeed. In the early 2000s, we were still occasionally using a C compiler written in the late 1980s because it was the only one to support both of the platforms upon which an older, but still supported, version of our product ran. Would it have been reasonable to re-write a legacy product solely so we could use a newer compiler? Of course not.//
And would your early-2000s product have passed lint? Would it have caused a modern day compiler to
? If so, then perhaps you are defending the wrong issue. Products that have inherent problems
the use of some tool or other that will ignore the improprieties are not to be tolerated. These sorts of products are destined to byte you in the buttocks, you betcha. Hiding bugs is
the same as squashing bugs.
//Yes. It
pass lint. By the way, it wasn't an early-2000s product as such. It was an early 90s product that was still being maintained as of the early-2000s.//
Okay. Can we stop discussing ancient history and get to modern times? If a currently-supported product has a history of bugs and can only be built under a very narrow set of tool and OS conditions then isn't this a clear sign that the product has built-in problems? Is it not our duty to recommend to the client that he think about a code audit to see where some of these potential problems may be hiding? Perhaps we can recommend some inexpensive tools for regression testing and such. All of this presumes the client is completely aghast at the idea of doing formal inspections, of course. Heh.
View edit of
February 6, 2011
with title or text search


text:
GreatNonprofits is the best way to find great local nonprofits.
Volunteers and donors use GreatNonprofits to search for ratings and reviews of nonprofits in their town.
Featured Review
The Younique Foundation
I was in the first group of women to attend the Haven Retreat. You would think that as a nonprofit first starting out there would be so many kinks to work out. I am sure they have tweaked things as they... more
Are you a nonprofit?
Hot Topics
How Our Brains Connect through Stories
The GreatNonprofits Fundraising Checklist
The Perks of Being a Volunteer: My experience as a virtual volunteer with GreatNonprofits
Top 10 Volunteer Opportunities in Atlanta
Top 10 Volunteer Opportunities in Chicago
10 Ways You Can Actually Help Syrian Refugees
Chagrin Falls Nonprofits and Charities
The Galen Foundation dba PeopleBeatingCancer
4.83333 stars 18 reviews
Dean W. wrote:
I gave found the Galen foundation to be extremely helpfull with my myeloma ex and giving me understanding of the disease process... more »
Taos Institute
5 stars 1 review
Samuelmahaffy wrote:
The Taos Institute is a community of scholars and practitioners that is global in its scope. It is at the cutting edge of developing... more »
0 stars 0 reviews
- Location:
- Cleveland, OH
Human Services
Stark Association Of Plumbing Heating & Cooling Contractors Inc-
0 stars 0 reviews
Jagetia Family Foundation
0 stars 0 reviews
- Location:
- Orange Village, OH
United Methodist Foundation Of Chagrin Falls
0 stars 0 reviews
Ato Charities
0 stars 0 reviews
- Location:
- Auburn Twp, OH
International Association Of Lions Clubs
0 stars 0 reviews
Bomber Elite Inc
0 stars 0 reviews
Chagrin Falls Historical Society
0 stars 0 reviews
Nonprofits and Charities in Other Cities
Whether your causes are animal shelters, food banks, or breast cancer groups, you'll find real nonprofit reviews you can trust at GreatNonprofits.
Millions of nonprofit clients, donors, and volunteers have shared their candid reviews of charities, nonprofits, and social enterprises.
Add your nonprofit reviews and help other donors and volunteers find a great nonprofit.
- Albuquerque Charities
- Atlanta Charities
- Austin Charities
- Bakersfield Charities
- Baltimore Charities
- Boston Charities
- Charlotte Charities
- Chicago Charities
- Cleveland Charities
- Columbus Charities
- Corpus Christi Charities
- Dallas Charities
- Denver Charities
- Detroit Charities
- El Paso Charities
- Fort Worth Charities
- Fresno Charities
- Houston Charities
- Honolulu Charities
- Indianapolis Charities
- Jacksonville Charities
- Kansas City Charities
- Las Vegas Charities
- Los Angeles Charities
- Louisville Charities
- Memphis Charities
- Miami Charities
- Milwaukee Charities
- Minneapolis Charities
- Nashville Charities
- New Orleans Charities
- New York Charities
- Oklahoma City Charities
- Omaha Charities
- Pittsburgh Charities
- Philadelphia Charities
- Phoenix Charities
- Portland Charities
- Raleigh Charities
- Riverside Charities
- Sacramento Charities
- San Antonio Charities
- San Diego Charities
- San Francisco Charities
- San Jose Charities
- Santa Ana Charities
- Seattle Charities
- Sonoma Charities
- St. Louis Charities
- Tampa Charities
- Tucson Charities
- Tulsa Charities
- Washington DC Charities
- Wichita Charities
- View All Cities
- View by State


text:
Firefall Announces Beta Weekends
Red 5 Studios has announced today that they will host a series of Firefall "Beta Weekends," giving thousands of players 48-hour beta access to stress test the game's servers and experience Firefall's gameplay first hand.
Upcoming Beta Weekends are scheduled for November 30 – December 2, and December 7 – December 9. These tests are for North America and Europe, and you can grab your own key here at MMOHut!
CEO of Red 5 Studios, Mark Kern, commented:
"We've seen an overwhelming demand for access to Firefall's beta since we began testing last year. The fact is, the growing number of registered players continues to outpace our servers and with closed beta testing going into 2013 that won't change in the short-term. These Beta Weekends are the solution. We're inviting thousands of new players to temporarily join Firefall for some huge server stress-tests, giving us valuable feedback, giving them a taste of the game, and helping to prepare Firefall for much larger numbers."
Red 5 has also announced the launch of its "Founders Rewards" program, designed to reward founding members exclusive items for helping the game reach its funding goals. As each funding goal is reached, founders are rewarded with a different item. So far, the game has reached its first funding goal, and has given all founders a pair of Virtual Camouflage Goggles. New players can access all the founder's rewards at any time they purchase a Founders Pack.
Next Article
Articles You May Enjoy
- Pocket Platoons: Now Available
- En Masse Entertainment, publisher of TERA — one of the most-played MMORPGs on Steam— is excited to announce today's launch of Pocket Pla...
- Shikihime Zoushi Concludes Beta Phase
- The markers of Shikihime Garden have teamed up with gamigo to unveil a new take on the Shikihime universe in Shikihime Zoushi.


text:
Business Segment
Blue Star Service Banner with Crossbar and Gold Cord and Tassels- Nyl-Glo- 8 in. X 15 in.$9.90
This item is currently on backorder. Backordered items typically ship in 5 to 7 business days.
This standard is displayed by immediate family members of a person serving in the Armed Forces during a period of war. Annin Flagmakers Is an authorized manufacturer of the Service Star Banner and Flag. Learn More
Nylon Yellow Bow 16 in.$7.20Made from 100% Nylon. 16 in. brightly colored bow allowing it to stand out. Strong and durable- perfect for outdoor use and decoration. Learn More
Support Our Troops Streamer Polyester- 4 in. X 45 in.$7.00Show your support for our troops during America's time of challenge. This version has a vertical layout and works well when displayed alone or with an American Flag Set Learn More


text:
All Posts In » 2012 » April » 17
Turning Japanese Weekly News (April 11th – April 24th)
New People Presents Artist Village Vol. 5 to Celebrate Cherry Blossom Festival Eclectic Art Market Takes Over Dynamic J-Town Venue For Two Consecutive Weekends This Month With Works From A Talented Mix Of Local Asian And Western-Influenced Artists NEW PEOPLE, the dynamic San Francisco entertainment destination bringing the latest examples of Japanese popular culture to North American shores, teams up with BAZAAR BIZARRE SAN FRANCISCO to celebrate the 45th Annual Cherry Blossom Festival and present the NEW PEOPLE ARTIST VILLAGE Vol. 5 – a fun and festive vertical arts and crafts show to be stationed throughout the spacious Japantown venue for two consecutive weekends – April 14th / 15th and April 21st / 22nd from 11:00am to 6:00pm each day. The free event extends the Bay Area's yearly celebration of Asian tradition with a dozen unique artists and merchants, stationed in colorfully decorated kiosks throughout the building, offering an eclecticRead more →By Vanessa in Turning Japanese No comments yet
Master Chief is back this November
If you're a Halo fan looking forward to the next entry in the series, Halo 4, it's time to circle Nov. 6 on your calendar, because that's the day you'll start losing a little bit of your life to 343 Industries' game release, set four years after the events of Halo 3. "We are beginning a new saga with 'Halo 4' and embarking on a journey that will encompass the next decade of 'Halo' games and experiences," said Phil Spencer, corporate vice president of Microsoft Studios. "Millions of fans worldwide have been eagerly awaiting the opportunity to step back into the boots of Master Chief, and, with 'Halo 4' leading the charge, we're confident 2012 will be the most successful year in Xbox history." Tonight on "Conan," host Conan O'Brien will have some sort of special segment about the game. The show airs at 11 Eastern. FollowRead more →By Tiffany Nevin in News No comments yet


text:
Top Definition
When someone straight beats on another person, usually with alot of extreme force
He just was molly wopped with that bat
di sir molly wopper 14 marzo 2005
Trending Now
Can you define these popular missing words?
verb; To be smacked violently upside the head.
Fool, you just straight mollywopped me, negroid!
di Cole 13 settembre 2004


text:
Top Definition
a guys "thing" which he puts in the girls hood
"dang girl! his ornament is HUGE!"
"his ornament felt amazing in my hood"
"his ornament felt amazing in my hood"
by KateKT January 10, 2006
Trending Now
Can you define these popular missing words?
a very fake person who bandwagons to whatever the "popular kids" thinks is cool
Nick is such an ornament, its really annoying
by Fagito 99 December 13, 2004


text:
A 50-year-old Ypsilanti woman was arrested Thursday for threatening the other tenants in her apartment building with an axe, police said.
Police say she was upset with the amount of noise they were making.
Officers were called to the 200 block of North Hamilton Street in Ypsilanti at 6:30 p.m. the incident.
The 50-year-old was arrested for felonious assault.
There was no further information about the incident.
John Counts covers crime and breaking news for The Ann Arbor News. He can be reached at email@example.com or you can follow him on Twitter. Find all Washtenaw County crime stories here.


text:
A fun destination for after school
Maranda and five-year-old Ava spent the day together at Catch Air.
Maranda and five-year-old Ava spent the day together at Catch Air.
WOTV 4's Jordan Carson sat down with two of this season's stars, Bindi Irwin and Nick Carter. Get the inside scoop on the season!
Capture the sweet flavors of autumn with these fall desserts.
Find a car seat check event near you during National Child Passenger Safety Week September 13 – 19.
Stay warm all year-long with more soup, stew, chowder and chili recipes.
Kent District Library is offering a series of fun events meant for grandparents and their grandchildren.
Apple unveiled new products including the iPhone 6S and Apple TV. Learn more about them.
Gail Saukas explains where you can donate your old cell phones to make an impact in someone's life.
Michele Fife explains why one spice can make a whole difference in your health.
Fall is on its way and so are a ton of great festivals to attend in West Michigan. Here's a list to get you started.
Whether we know a person for five minutes or 50 years, being nice to the people around you can make a difference and might even save a life.
Check out this list of bestselling romance books to warm you up when the weather gets cool.
A satisfying and flavorful meal on the table with our Healthy Eats expert, Margaux Drake's quick fall curry.
Enjoy the football season with your girlfriends!
A mom's money saving secrets for kids clothing.
Find the perfect items for your wedding at the Fall Bridal Show at DeVos Place!
The Grand Valley American Indian Lodge holds its 54th annual Traditional Pow Wow on September 12 and 13.
The book helped the writers work through the loss of loved ones.
The Grand Rapids Phoenix is a basketball team for kids in grades third through sixth.
GRAND RAPIDS, Mich. (WOTV) — It's time to have the paper and crayons handy, because the kids will soon be making their Christmas lists. Toys…
Saving lives can be as simple as being nice with the "be nice." campaign supported by Elhart Automotive and Mental Health Foundation of West…
20 of the most wearable fashions for fall 2015.
The conference, held in Grand Rapids, will promote safe habits while on the road.
"Maranda Where You Live" will air at 4:30 p.m. on WOTV 4 Women starting September 14.
What roommate type will you have this year? Here are some common types.


text:
West Nile Virus
West Nile Virus (WNV) is a potentially serious illness most often spread by the bite of an infected mosquito. The virus is not transmitted from person-to-person. You cannot get it from touching or kissing a person who has the virus or from a health care worker who has treated someone with it.
WNV can infect humans, birds, mosquitoes, horses, and some other mammals. Human WNV cases are more common in late summer and early fall but can occur in any mild climate.
Most people infected with the West Nile virus have no symptoms of illness. If symptoms do occur, the most common are: a mild illness with fever, headache and body aches, sometimes with skin rash and swollen lymph glands. WNV may under some circumstances cause encephalitis (an inflammation of the brain). The syptoms of encephalitis may include headache, high fever, stiff neck, change in mental status, disorientation, coma, tremors, convulsions, muscle weakness and paralysis.
If you have symptoms of encephalitis, call or visit your clinician as soon as possible for assessment.
There is no vaccine or treatment for WNV infection. Preventing mosquito bites is the best way to avoid infection:
- Apply insect repellent containing DEET (look for N,N-diethyl-metatoluamide on the label) or permethrin to skin and clothing when going outdoors.
- See Environmental Protection Agency (EPA) guidance on How to Use Insect Repellents Safely.
- Wear long sleeves, pants, and socks, if possible.
- Maintain window and door screening to keep mosquitoes out of buildings.
Treating mosquito breeding sites helps prevent spread of WNV. Mosquitoes lay their eggs in standing water. Examples of breeding sites include flower pots, pet bowls, clogged rain gutters, buckets, barrels, or cans. It takes about 1 week for eggs to mature, so it's important to eliminate breeding sites at once. Dead birds may be a sign that WNV is circulating between birds and mosquitoes in an area.
Report possible mosquito breeding sites and dead birds on UCSD property:
- Report mosquito breeding sites to:
- Plant Building and Grounds Services
Pest Management Services
109 E. Madison
Ann Arbor, MI 48104, or
Phone: (734) 764-0532 or (734) 647-2059
- Dead birds:
- If found on campus:
- Contact UM Plant Services at: (734) 647-2059
- If found off-campus:
- Complete the State of Michigan Sick or Dead Bird & Mammal Reporting Web Form, or Phone: (888) 668-0869
- The above form may also be completed on the Washtenaw County Health Department West Nile Virus Informational Site
Phone: (734) 544-6750
Additional Information
- Univeristy of Michigan Health Services: West Nile Virus
Useful External Links
- CDC: Fight the Bite!
- EPA: Mosquito Control Methods
- State of Michigan: About West Nile Virus
- USGS: Disease Maps
- Washtenaw County Health Department: West Nile Virus


text:
Biomaterials (v.29, #22)
Editorial board (IFC).
Universal cell labelling with anionic magnetic nanoparticles by Claire Wilhelm; Florence Gazeau (3161-3174).
Magnetic labelling of living cells creates opportunities for numerous biomedical applications, from individual cell manipulation to MRI tracking. Here we describe a non-specific labelling method based on anionic magnetic nanoparticles (AMNPs). These particles first adsorb electrostatically to the outer membrane before being internalized within endosomes. We compared the labelling mechanism, uptake efficiency and biocompatibility with 14 different cell types, including adult cells, progenitor cells, immune cells and tumour cells. A single model was found to describe cell/nanoparticle interactions and to predict uptake efficiency by all the cell types. The potential impact of the AMNP label on cell functions, in vitro and in vivo, is discussed according to cellular specificities. We also show that the same label provides sufficient magnetization for MRI detection and distal manipulation.
Keywords: Iron oxide nanoparticles; Magnetism; MRI; Biocompatibility; Cell therapy; Cell manipulation;
Thermoresponsive nanocomposite hydrogels with cell-releasing behavior by Yaping Hou; Andrew R. Matthews; Ashley M. Smitherman; Allen S. Bulick; Mariah S. Hahn; Huijie Hou; Arum Han; Melissa A. Grunlan (3175-3184).
Poly(N-isopropylacrylamide) (PNIPAAm) hydrogels become more hydrophobic when they reversibly switch from a water-swollen to a deswollen state above the volume phase transition temperature (VPTT, ∼33 °C) which has been used to modulate cell adhesion. In the current work, we prepared novel thermoresponsive nanocomposite hydrogels comprised of a PNIPAAm hydrogel matrix and polysiloxane colloidal nanoparticles (∼220 nm average diameter) via in situ photopolymerization of aqueous solutions of NIPAAm monomer, N,N′-methylenebisacrylamide (BIS, crosslinker), photoinitiator and polysiloxane nanoparticles (0.5–2.0 wt% based on solution weight) at ∼7 °C. The VPTT of the nanocomposite hydrogels is not altered versus the pure PNIPAAm hydrogel. Dynamic mechanical analysis and tensile tests revealed that higher nanoparticle content generally produced improved hydrogel mechanical properties. Surfaces of nanocomposite hydrogels became increasingly more hydrophobic at all temperatures between 10 and 40 °C as the amount of hydrophobic polysiloxane nanoparticles was increased. When cooled from 37 to 25 °C, mouse smooth muscle precursor cells (10T1/2) were effectively detached from nanocomposite hydrogel surfaces. The utility of photopatterning to create surface micropillars comprised of nanocomposite hydrogels was demonstrated.
Keywords: Hydrogel; Thermally responsive material; Siloxane; Nanoparticles; Cell adhesion; Photopolymerization;
Synthesis and water-swelling of thermo-responsive poly(ester urethane)s containing poly(ε-caprolactone), poly(ethylene glycol) and poly(propylene glycol) by Xian Jun Loh; Kian Boon Colin Sng; Jun Li (3185-3194).
Thermo-responsive multiblock poly(ester urethane)s comprising poly(ε-caprolactone) (PCL), poly(ethylene glycol) (PEG), and poly(propylene glycol) (PPG) segments were synthesized. The copolymers were characterized by GPC, NMR, FTIR, XRD, DSC and TGA. Water-swelling analysis carried out at different temperatures revealed that the bulk hydrophilicity of the copolymers could be controlled either by adjusting the composition of the copolymer or by changing the temperature of the environment. These thermo-responsive copolymer films formed highly swollen hydrogel-like materials when soaked in cold water and shrank when soaked in warm water. The changes are reversible. The mechanical properties of the copolymer films were assessed by tensile strength measurement. These copolymers were ductile when compared to PCL homopolymers. Young's modulus and the stress at break increased with increasing PCL content, whereas the strain at break increased with increasing PEG content. The results of the cytotoxicity tests based on the ISO 10993-5 protocol demonstrated that the copolymers were non-cytotoxic and could be potentially used in biomedical applications.
Keywords: Biodegradable; Stimuli-responsive; Poly(ester urethane); Poly(ε-caprolactone); Poly(ethylene glycol); Poly(propylene glycol);
Simultaneous in vivo comparison of bone substitutes in a guided bone regeneration model by Dieter Busenlechner; Stefan Tangl; Birgit Mair; Georg Fugger; Reinhard Gruber; Heinz Redl; Georg Watzek (3195-3200).
A direct, simultaneous comparison of bone substitutes is hampered by the limited number of samples that can be tested simultaneously. The goal of this study was to establish a preclinical model for guided bone regeneration that offers testing of different bone substitutes in a one-wall defect situation. We show here that up to eight titanium hemispheres can be placed on the calvaria of minipigs. To establish our model, titanium hemispheres were filled with and without Bio-Oss®, a deproteinized bovine bone mineral, Ostim®, an aqueous paste of synthetic nanoparticular hydroxyapatite, and Osteoinductal®, an oily calcium hydroxide suspension, before being positioned on the calvaria. After 6 and 12 weeks, titanium hemispheres were subjected to histological and histomorphometric analysis. We show here that bone filled approximately one-tenth of the area below the hemispheres which were left empty, indicating a critical size model for guided bone regeneration. In accordance with the documented osteoconductive properties of Bio-Oss® and Ostim®, titanium hemispheres were almost completely filled with bone. Moreover, the expected degradation profile of Bio-Oss® and Ostim® could be confirmed by histologic and histomorphometric analysis. Under the same conditions, Osteoinductal® failed to exert osteoconductive properties, rather a progressive resorption of the host bone was observed. These results demonstrate that the preclinical model presented here is suitable to simultaneously compare bone substitutes with different material properties. Our model based on the titanium hemispheres allows evaluation of graft consolidation under standardized conditions thereby avoiding intra-individual variations.
Keywords: In vivo test; Bone graft; Bone ingrowth; Bone regeneration; Osteoconduction; Degradation;
In vitro chondrogenic differentiation of human mesenchymal stem cells in collagen microspheres: Influence of cell seeding density and collagen concentration by T.Y. Hui; K.M.C. Cheung; W.L. Cheung; D. Chan; B.P. Chan (3201-3212).
Given the inadequacies of existing repair strategies for cartilage injuries, tissue engineering approach using biomaterials and stem cells offers new hope for better treatments. Recently, we have fabricated injectable collagen–human mesenchymal stem cell (hMSC) microspheres using microencapsulation. Apart from providing a protective matrix for cell delivery, the collagen microspheres may also act as a bio-mimetic matrix facilitating the functional remodeling of hMSCs. In this study, whether the encapsulated hMSCs can be pre-differentiated into chondrogenic phenotype prior to implantation has been investigated. The effects of cell seeding density and collagen concentration on the chondrogenic differentiation potential of hMSCs have been studied. An in vivo implantation study has also been conducted. Fabrication of cartilage-like tissue micro-masses was demonstrated by positive immunohistochemical staining for cartilage-specific extracellular matrix components including type II collagen and aggrecan. The meshwork of collagen fibers was remodeled into a highly ordered microstructure, characterized by thick and parallel bundles, upon differentiation. Higher cell seeding density and higher collagen concentration favored the chondrogenic differentiation of hMSCs, yielding increased matrix production and mechanical strength of the micro-masses. These micro-masses were also demonstrated to integrate well with the host tissue in NOD/SCID mice.
Keywords: Chondrogenic differentiation; Mesenchymal stem cell; Collagen; Microspheres; Cartilage; Tissue engineering;
Transient elastic support for vein grafts using a constricting microfibrillar polymer wrap by Mohammed S. El-Kurdi; Yi Hong; John J. Stankus; Lorenzo Soletti; William R. Wagner; David A. Vorp (3213-3220).
Arterial vein grafts (AVGs) often fail due to intimal hyperplasia, thrombosis, or accelerated atherosclerosis. Various approaches have been proposed to address AVG failure, including delivery of temporary mechanical support, many of which could be facilitated by perivascular placement of a biodegradable polymer wrap. The purpose of this work was to demonstrate that a polymer wrap can be applied to vein segments without compromising viability/function, and to demonstrate one potential application, i.e., gradually imposing the mid-wall circumferential wall stress (CWS) in wrapped veins exposed to arterial levels of pressure.Poly(ester urethane)urea, collagen, and elastin were combined in solution, and then electrospun onto freshly-excised porcine internal jugular vein segments. Tissue viability was assessed via Live/Dead™ staining for necrosis, and vasomotor challenge with epinephrine and sodium nitroprusside for functionality. Wrapped vein segments were also perfused for 24 h within an ex vivo vascular perfusion system under arterial conditions (pressure = 120/80 mmHg; flow = 100 mL/min), and CWS was calculated every hour.Our results showed that the electrospinning process had no deleterious effects on tissue viability, and that the mid-wall CWS vs. time profile could be dictated through the composition and degradation of the electrospun wrap. This may have important clinical applications by enabling the engineering of an improved AVG.
Keywords: Electrospinning; Vein graft; Intimal hyperplasia; Vein wrap;
The application of human bone marrow stromal cells and poly(dl-lactic acid) as a biological bone graft extender in impaction bone grafting by Benjamin J.R.F. Bolland; Janos M. Kanczler; Patrick J. Ginty; Steve M. Howdle; Kevin M. Shakesheff; Douglas G. Dunlop; Richard O.C. Oreffo (3221-3227).
Concerns over disease transmission, high costs and limited supply have led to interest in synthetic grafts in the field of impaction bone grafting (IBG). Poly(dl-lactic acid) (PLA) grafts are attractive alternatives due to their biocompatibility, established safety and versatile manufacturing process. This study examined the potential of PLA scaffolds augmented with human bone marrow stromal cells (HBMSCs) in IBG. In vitro and in vivo studies were performed on impacted morsellised PLA seeded with HBMSC and compared to PLA alone. In vitro samples were incubated under osteogenic conditions and in vivo samples were implanted subcutaneously into severely compromised immunodeficient mice, for 4 weeks. Biochemical, histological, mechanical and 3D micro-computed tomography analyses were performed. HBMSC viability, biochemical activity and histological evidence of osteogenic cellular differentiation, post-impaction were observed in vitro and in vivo in PLA/HBMSC samples compared to impacted PLA alone. In vitro PLA/HBMSC samples demonstrated evidence of mechanical enhancement over PLA alone. In vivo studies showed a significant increase in new bone and blood vessel formation in the PLA/HBMSC constructs compared to PLA alone. With alternatives to allograft being sought, these studies have demonstrated PLA/HBMSC living composites, to be a potential prospect as a biological bone graft extender for future use in the field of IBG.
Keywords: Impaction bone grafting; Bone graft extenders; Poly(dl-lactic acid); Tissue engineering; Neovascularisation;
Tissue-to-cellular level deformation coupling in cell micro-integrated elastomeric scaffolds by John A. Stella; Jun Liao; Yi Hong; W. David Merryman; William R. Wagner; Michael S. Sacks (3228-3236).
In engineered tissues we are challenged to reproduce extracellular matrix and cellular deformation coupling that occurs within native tissues, which is a meso-micro scale phenomenon that profoundly affects tissue growth and remodeling. With our ability to electrospin polymer fiber scaffolds while simultaneously electrospraying viable cells, we are provided with a unique platform to investigate cellular deformations within a three dimensional elastomeric fibrous scaffold. Scaffold specimens micro-integrated with vascular smooth muscle cells were subjected to controlled biaxial stretch with 3D cellular deformations and local fiber microarchitecture simultaneously quantified. We demonstrated that the local fiber geometry followed an affine behavior, so that it could be predicted by macro-scaffold deformations. However, local cellular deformations depended non-linearly on changes in fiber microarchitecture and ceased at large strains where the scaffold fibers completely straightened. Thus, local scaffold microstructural changes induced by macro-level applied strain dominated cellular deformations, so that monotonic increases in scaffold strain do not necessitate similar levels of cellular deformation. This result has fundamental implications when attempting to elucidate the events of de-novo tissue development and remodeling in engineered tissues, which are thought to depend substantially on cellular deformations.
Keywords: Cellular deformations; Tissue engineering; Elastomeric scaffolds; Mechanobiology;
A gel-free 3D microfluidic cell culture system by Siew-Min Ong; Chi Zhang; Yi-Chin Toh; So Hyun Kim; Hsien Loong Foo; Choon Hong Tan; Danny van Noort; Sungsu Park; Hanry Yu (3237-3244).
3D microfluidic cell culture systems offer a biologically relevant model to conduct micro-scale mammalian cell-based research and applications. Various natural and synthetic hydrogels have been successfully incorporated into microfluidic systems to support mammalian cells in 3D. However, embedment of cells in hydrogels introduces operational complexity, potentially hinders mass transfer, and is not suitable for establishing cell-dense, ECM-poor constructs. We present here a gel-free method for seeding and culturing mammalian cells three-dimensionally in a microfluidic channel. A combination of transient inter-cellular polymeric linker and micro-fabricated pillar arrays was used for the in situ formation and immobilization of 3D multi-cellular aggregates in a microfluidic channel. 3D cellular constructs formed this way are relieved of hydrogel embedment for cellular support. Two mammalian cell lines (A549 and C3A) and a primary mammalian cell (bone marrow mesenchymal stem cells) were cultured in the gel-free 3D microfluidic cell culture system. The cells displayed 3D cellular morphology, cellular functions and differentiation capability, affirming the versatility of the system as a 3D cell perfusion culture platform for anchorage-dependent mammalian cells.
Keywords: 3D in vitro cell culture; Cell aggregates; Microfluidics; Perfusion culture; Transient inter-cellular polymeric linker; Hydrogel;
Retention of in vitro and in vivo BMP-2 bioactivities in sustained delivery vehicles for bone tissue engineering by Diederik H.R. Kempen; Lichun Lu; Teresa E. Hefferan; Laura B. Creemers; Avudaiappan Maran; Kelly L. Classic; Wouter J.A. Dhert; Michael J. Yaszemski (3245-3252).
In this study, we investigated the in vitro and in vivo biological activities of bone morphogenetic protein 2 (BMP-2) released from four sustained delivery vehicles for bone regeneration. BMP-2 was incorporated into (1) a gelatin hydrogel, (2) poly(lactic-co-glycolic acid) (PLGA) microspheres embedded in a gelatin hydrogel, (3) microspheres embedded in a poly(propylene fumarate) (PPF) scaffold and (4) microspheres embedded in a PPF scaffold surrounded by a gelatin hydrogel. A fraction of the incorporated BMP-2 was radiolabeled with 125I to determine its in vitro and in vivo release profiles. The release and bioactivity of BMP-2 were tested weekly over a period of 12 weeks in preosteoblast W20-17 cell line culture and in a rat subcutaneous implantation model. Outcome parameters for in vitro and in vivo bioactivities of the released BMP-2 were alkaline phosphatase (AP) induction and bone formation, respectively. The four implant types showed different in vitro release profiles over the 12-week period, which changed significantly upon implantation. The AP induction by BMP-2 released from gelatin implants showed a loss in bioactivity after 6 weeks in culture, while the BMP-2 released from the other implants continued to show bioactivity over the full 12-week period. Micro-CT and histological analysis of the delivery vehicles after 6 weeks of implantation showed significantly more bone in the microsphere/PPF scaffold composites (Implant 3, p < 0.02). After 12 weeks, the amount of newly formed bone in the microsphere/PPF scaffolds remained significantly higher than that in the gelatin and microsphere/gelatin hydrogels (p < 0.001), however, there was no statistical difference compared to the microsphere/PPF/gelatin composite. Overall, the results from this study show that BMP-2 could be incorporated into various bone tissue engineering composites for sustained release over a prolonged period of time with retention of bioactivity.
Keywords: Bioactivity; Bone morphogenetic protein; Controlled drug release; Ectopic bone formation; Gelatin; Poly(lactic-co-glycolic acid) microspheres;
The use of RANKL-coated brushite cement to stimulate bone remodelling by Damien Le Nihouannen; S. Adam Hacking; Uwe Gbureck; Svetlana V. Komarova; Jake E. Barralet (3253-3259).
Calcium phosphate cements were first proposed as synthetic bone substitutes over two decades ago, however, they are characterised by slow chemical or cellular resorption and a slow osteointegration. In contrast, bone autograft has been shown to stimulate osteoclastogenesis and angiogenesis resulting in active bone remodelling and rapid graft incorporation. Therefore, we aimed to develop a biomaterial able to release a key stimulator of the bone remodelling process, cytokine RANKL. Cylinders of brushite cement, hydroxyapatite cement and sodium alginate were loaded with RANKL either by incorporation into the cement or by coating the material with soluble RANKL. To test the biological activity of these formulations, we assessed their effectiveness in inducing osteoclast formation from RAW 264.7 monocytic cell line. Only brushite and hydroxyapatite cements coated with RANKL allowed for retaining sufficient biological activity to induce osteoclast formation. Most efficient was coating 40 mg cylinder of brushite cement with 800 ng RANKL. We have found that RANKL-coated brushite cement exhibits osteoclastogenic activity for at least 1 month at 37 °C. Thus, we developed a formulation of brushite cement with RANKL – a synthetic bone graft that is similar to autografts in its ability to actively induce osteoclastogenesis.
Keywords: Calcium phosphate cement; Brushite; RANKL; Osteoclast; Controlled drug release;
The effect of sulfation of alginate hydrogels on the specific binding and controlled release of heparin-binding proteins by Inbar Freeman; Alon Kedem; Smadar Cohen (3260-3268).
To mimic the high affinity of heparin-binding proteins to heparin/heparan sulfate, the uronic acids in non-sulfated alginate were sulfated, and hydrogels of mixed alginate/alginate-sulfate were fabricated. Surface plasmon resonance analysis probed the interactions of 13 proteins with alginate-sulfate. Of these, the 10 heparin-binding proteins revealed strong binding to alginate-sulfate and heparin, but not to alginate. The equilibrium binding constants to alginate-sulfate were comparable or one order of magnitude higher than those obtained between the proteins and heparin. Only the fibroblast growth factors (FGFs) revealed higher affinity for heparin than to alginate-sulfate. Sulfation of hyaluronan, as well, resulted in strong binding of basic FGF to hyaluronan-sulfate, but not to hyaluronan. Mixed hydrogels of alginate/alginate-sulfate sustained the release of basic FGF, with the release rate being dependent on the percentage of bFGF bound to the hydrogels. In vivo, the delivery of bFGF bound to alginate/alginate-sulfate scaffolds induced the formation of twice the number of blood vessels compared to when bFGF was delivered adsorbed to the matrix and 51% of the vessels were matured, as judged by pericyte coverage of the vessels. Our results thus describe the engineering of alginate hydrogels for the spatially presentation and controlled delivery of heparin-binding proteins.
Keywords: Affinity binding; Biomimetics; Angiogenesis; bFGF; Hyaluronic acid; Sulfation of polysaccharides;
Biodegradable arginine-based poly(ester-amide)s as non-viral gene delivery reagents by Dai Yamanouchi; Jun Wu; Andrew N. Lazar; K. Craig Kent; Chih-Chang Chu; Bo Liu (3269-3277).
A novel family of synthetic biodegradable poly(ester-amide)s (Arg-PEAs) was evaluated for their biosafety and capability to transfect rat vascular smooth muscle cells, a major cell type participating in vascular diseases. Arg-PEAs showed high binding capacity toward plasmid DNA, and the binding activity was inversely correlated to the number of methylene groups in the diol segment of Arg-PEAs. All Arg-PEAs transfected smooth muscle cells with an efficiency that was comparable to the commercial transfection reagent Superfect®. However, unlike Superfect®, Arg-PEAs, over a wide range of dosages, had minimal adverse effects on cell morphology, viability or apoptosis. Using rhodamine-labeled plasmid DNA, we demonstrated that Arg-PEAs were able to deliver DNA into nearly 100% of cells under optimal polymer-to-DNA weight ratios, and that such a high level of delivery was achieved through an active endocytosis mechanism. A large portion of DNA delivered, however, was trapped in acidic endocytotic compartments, and subsequently was not expressed. These results suggest that with further modification to enhance their endosome escape, Arg-PEAs can be attractive candidates for non-viral gene carriers owning to their high cellular uptake nature and reliable cellular biocompatibility.
Keywords: Gene transfer; Nanoparticle; Smooth muscle cell; MTT assay; Image analysis; Fluorescence;
An electrochemical fabrication process for the assembly of anisotropically oriented collagen bundles by Xingguo Cheng; Umut A. Gurkan; Christopher J. Dehen; Michael P. Tate; Hugh W. Hillhouse; Garth J. Simpson; Ozan Akkus (3278-3288).
Controlled assembly of collagen molecules in vitro remains a major challenge for fabricating the next generation of engineered tissues. Here we present a novel electrochemical alignment technique to control the assembly of type-I collagen molecules into highly oriented and densely packed elongated bundles at the macroscale. The process involves application of electric currents to collagen solutions which in turn generate a pH gradient. Through an isoelectric focusing process, the molecules migrate and congregate within a plane. It was possible to fabricate collagen bundles with 50–400 μm diameter and several inches length via this process. The current study assessed the orientational order, and the presence of fibrillar assembly in such electrochemically oriented constructs by polarized optical microscopy, small angle X-ray scattering, second harmonic generation, and electron microscopy. The mechanical strength of the aligned crosslinked collagen bundles was 30-fold greater than its randomly oriented-crosslinked counterpart. Aligned crosslinked collagen bundles had about half the strength of the native tendon. Tendon-derived fibroblast cells were able to migrate and populate multiple macroscopic bundles at a rate of 0.5 mm/day. The anisotropic order within biocompatible collagenous constructs was conferred upon the nuclear morphology of cells as well. These results indicate that the electrochemically oriented collagen scaffolds carry baseline characteristics to be considered for tendon/ligament repair.
Keywords: Assembly; Collagen; Electrochemistry; Biomimetic materials; Connective tissues;


text:
Objectives of the consultation
In its Communication on "A sustainable future for transport: Towards an integrated, technology-led and user friendly system", the Commission is encouraging all interested parties to contribute their views on what policy measures are needed to address the future challenges of the transport sector.
Take part in the debate
The Commission encourages all interested party to contribute to the consultation exercise launched by this Communication. Views on the future of transport and on possible policy options should be submitted to the mailbox: firstname.lastname@example.com by 30 September 2009.


text:
The Society of Military History will hold its 71st Annual Meeting under the auspices of the Department of History, University of Maryland, College Park, at the Hyatt Regency Hotel in Bethesda, Maryland. The conference theme is "What's on Our Minds: Critical Problems in Military History." The main purpose of the conference is to address issues that define the field as a serious academic activity and medium of public policy discourse. This approach should engage the attention of the large military and civilian governmental audience that resides in the region surrounding the nation's capital, as well as encourage the participation of leading military historians. The Program Committee especially invites proposals for papers and panels that will address such general issues as military institutional transformation, professional military education, strategy and politics, the relationship of historical understanding and policy-making, and the economic dimensions of national security policy. As always, proposals for papers and panels treating all aspects of military history are welcome.
Proposals should include a one-page abstract for each paper, utlining topic, thesis, and sources, and a brief c.v. for all participants. The Program Committee intends to post the abstracts on the SMH Web site, http://www.smh-hq.org. The committee welcomes volunteers to serve as chairs and/or commentators. Volunteers are asked to provide a brief c.v.
The due date for paper and panel proposal submissions is October 1, 2003. The program committee will begin deliberations in October, but will accept late submissions until 1 November.


text:
Discussion in 'Kongai virtual card game' started by zakid, Mar 20, 2012.
Details here:
All random =(... anyway I'll try to make it but Saturday kinda sucks for me. Oh also if it's possible to gift Kreds, I can kick in 13 for the pot.
Separate names with a comma.


text:
First printing. Explains the significance of this biblical story to young adult readers. Illustrated with maps. 102 pages. Bound in illustrated boards which repeat the painting on the dustjacket cover. Ex-library but with few markings and overall tight and clean in a near fine dj. A very attractive copy of a rather uncommon Asimov title. .ISBN # 0-385-052081
Bookfever.com - Selling books on the internet, by mail order, at book fairs, and at Antiques Upstairs in historic downtown Jackson, California, since 1992. Over 50,000 books and magazines in stock (over 4,000 signed or inscribed by the author) - many more than are listed on our website, so please do not hesitate to contact us if you cannot find what you are looking for.FIND US ON FACEBOOK
updated 9/20/2015 8:51:50 PM
|TOLL FREE (877)-BOOKFEVer or (209)-274-6960


text:
APSO investigating Church Point death
Information has been provided by the Acadia Parish Sheriff's Office.
Authorities in Acadia Parish are investigating a death that occurred near Church Point earlier today.
According to Acadia Parish Sheriff Wayne Melancon, his office received a call concerning a grass fire behind a residence in the 8400 block of the Church Point Highway near Church Point. Upon arrival firefighters discovered that the homeowner was attempting to burn trash behind the home when the wind shifted trapping the 61-year-old woman resulting in injuries that caused her death.
Melancon stated that the Acadia Parish Coroners Office arrived at the scene and pronounced the victim dead. The woman's death is being treated as an accident. Her identity is being withheld pending family notification.


text:
The read and write APIs each have four layers: a public API layer, a format layer that understands the archive file format, a compression layer, and an I/O layer. The I/O layer is completely exposed to clients who can replace it entirely with their own functions.
In order to provide as much consistency as possible for clients, some public functions are virtualized. Eventually, it should be possible for clients to open an archive or disk writer, and then use a single set of code to select and write entries, regardless of the target.
The client read callback is expected to provide a block of data on each call. A zero-length return does indicate end of file, but otherwise blocks may be as small as one byte or as large as the entire file. In particular, blocks may be of different sizes.
The client skip callback returns the number of bytes actually skipped, which may be much smaller than the skip requested. The only requirement is that the skip not be larger. In particular, clients are allowed to return zero for any skip that they don't want to handle. The skip callback must never be invoked with a negative value.
Keep in mind that not all clients are reading from disk: clients reading from networks may provide different-sized blocks on every request and cannot skip at all; advanced clients may use mmap(2) to read the entire file into memory at once and return the entire file to libarchive as a single block; other clients may begin asynchronous I/O operations for the next block on each request.
A subsequent call to the Fn consume function advances the read pointer. Note that data returned from a Fn read_ahead call is guaranteed to remain in place until the next call to Fn read_ahead . Intervening calls to Fn consume should not cause the data to move.
Skip requests must always be handled exactly. Decompression handlers that cannot seek forward should not register a skip handler; the API layer fills in a generic skip handler that reads and discards data.
A decompression handler has a specific lifecycle:
The value returned by the bid function indicates its suitability for handling this data stream. A bid of zero will ensure that this decompressor is never invoked. Return zero if magic number checks fail. Otherwise, your initial implementation should return the number of bits actually checked. For example, if you verify two full bytes and three bits of another byte, bid 19. Note that the initial block may be very short; be careful to only inspect the data you are given. (The current decompressors require two bytes for correct bidding.)
For example, libarchive's ISO9660 support operates very differently from most ISO9660 readers. The libarchive support utilizes a work-queue design that keeps a list of known entries sorted by their location in the input. Whenever libarchive's ISO9660 implementation is asked for the next header, checks this list to find the next item on the disk. Directories are parsed when they are encountered and new items are added to the list. This design relies heavily on the ISO9660 image being optimized so that directories always occur earlier on the disk than the files they describe.
Depending on the specific format, such approaches may not be possible. The ZIP format specification, for example, allows archivers to store key information only at the end of the file. In theory, it is possible to create ZIP archives that cannot be read without seeking. Fortunately, such archives are very rare, and libarchive can read most ZIP archives, though it cannot always extract as much information as a dedicated ZIP program.


text:
First Trailer for the Touching Documentary 'Being Elmo'
Do you cry at the movies? Maybe it's because I'm a film-aholic but when a cinematic drama manages to squeeze a few drops of authenticity out of its subject (no easy feet), I'm one to get a little choked up. The end of The Iron Giant gets me every time.
For those of you find it difficult to strike up a good cry at the movies, I have something that's guaranteed to have you blowing through a pack of Kleenexes before the credits roll: Being Elmo: A Puppeteer's Journey. The documentary, which premiered at the Sundance Film Festival, tells the story of Kevin Clash, who, as a kid, dreamed of becoming a professional puppeteer and subsequently went on to change the industry forever. After being recruited as a teen, Kevin honed his skills and later befriended Jim Henson, who became his employer, mentor and friend.
One of Kevin's many achievements was the creation of Elmo—or rather, the Elmo we know today (the character was originally voiced by another puppeteer). As the doc recounts, the character grew into a worldwide phenomena, becoming a symbol of love and friendship for kids around the world. Oh boy, I'm already tearing up a bit.
Check out the first trailer for the film below and head to the film's official site to find out more about this must-see documentary.
Source: Indiewire
You can contact Matt Patches directly on Twitter @misterpatches and remember to follow@Hollywood_com!


text:
Hyatt Regency Newport Beach
1107 Jamboree Road
Newport Beach, California, USA, 92660
Tel: +1 949 729 1234
A Beautiful, Luxurious Resort-Style Newport Beach Hotel
Discover the quintessential resort experience, including rooms and suites with views, three beautiful pool environments, and a wonderful restaurant concept at our iconic resort-style hotel in Newport Beach, CA. Savor fresh regional seafood at SHOR American Seafood Grill, with its casually elegant atmosphere with indoor and alfresco dining for breakfast, lunch, and dinner.
For more active vacations, Hyatt Regency Newport Beach features a 24-hour StayFit™ Gym and a beautiful on-site nine-hole golf course. We are a stone's throw from Newport Dunes for paddle boarding, kayaking, and boat rentals, and minutes from Newport Beach's 10 miles of scenic coastline and world-class shopping. Experience the stunning ambiance and modern amenities of our landmark hotel during the popular Newport Beach Jazz Festival and Summer Concert Series.
Resident Reward Offering
Hyatt Regency Newport Beach introduces their Resident Reward offerings for guests interested in staying 14 or more consecutive nights.
Pack the leash, your four-legged family member is welcome...
Follow Us on Facebook
Hyatt Regency Newport Beach is on Facebook
For Kids By Kids Restaurant Menu
We embarked on the next step in Hyatt's food and beverage journey and our ongoing commitment to our guests by announcing the launch of our "For Kids By Kids," children's menu.


text:
Introduction to Roth IRA Accounts
Roth 401k/403b plans
What is a Roth IRA?
Privacy Policy
Copyright 2008 - 2011 - RothAccounts.com
Traditional retirement accounts
have always touted the benefits of saving for
your retirement. The promise of tax-deferred savings makes your savings grow
quickly. However, there's a trade-off. The assumption of traditional accounts is that
you will pay less on taxes when you're retired than you will now when working. And
unfortunately, when that bite comes, it may be bigger than you assumed. The
beauty of using a Roth retirement account is that it avoids paying taxes altogether
on both contributions and earnings. This is because those same taxes are already
paid on the money you deposit. As a result, keeping within the limitations of the
account use, and no new taxes will ever be owed. In essence the Roth is
technically a tax shelter for retirement savings, but it's not illegal like a bank
account in some Caribbean bank offshore. Roth accounts in general were first
created in 1998 with the Roth Individual Retirement Account (IRA). The name was
in honor of a Delaware senator who pushed the authorizing legislation through
Congress. Today just about anyone can open a Roth account IRA and even greater
benefits have become recently available:
When converting a traditional retirement account to a Roth required minimum
distributions are excluded from the formula to determine allowable income
limits (account holders are currently capped on how much adjusted gross
income they can make and deposit to a Roth IRA).
Inflation is not a factor in income limits. Roth IRA laws provide for inflation
indexing to those limits.
Beginning in 2008 if you have a distribution from one of your traditional
retirement accounts in your employer plan you don't first have to put it in a
traditional IRA. Instead it can go straight
into a Roth IRA without penalty
(translation – there is no tax bite for the
transfer. This is a huge benefit).
By 2010, there will no longer be an
adjusted gross income limit before you
can deposit via a Roth conversion (you
don't have to wait until you're making
less money to be eligible).
2006 brought the biggest shift in retirement
account laws when Congress created the
Roth accounts in 401k and 403b plans. This
new option is very similar in function to the
Roth IRA, but the big difference is that you can use it in conjunction with your
employer retirement plan. That allows you to keep matching contributions from your
employer. And you don't have to wait until employment separation to get into a Roth
account. Overall, both types of Roth accounts make it easier to build, preserve and
use your retirement savings and we'll go over each in some detail in the following
Next - Roth 401k/403b


text:
Availability: Out of stock
Email me when available.
This game opens up the skies of WWI for a new flying adventure. Fans of the WWII Down in Flames games will quickly learn the new rules and enjoy the new decisions and options offered by the new game. New fans will be up and flying within 15 minutes of reading the rules.


text:
Farm Insurance
Whether you are a weekend or full time farmer with a few acres or hundreds, the importance of protecting your hard work and effort is as imperative as any other business. Peoples Exchange Insurance can garner the right policy for you.
To obtain a free, no-obligation quote, fill out the form below and we will contact you. If you prefer to give information over the phone, please fill out your name and phone number and a representative will contact you shortly.
Please note that this insurance product is not FDIC insured; is not a deposit in, obligation of, guaranteed or underwritten by the bank/affiliate; and is not a condition of any bank service.


text:
For 20 years, a city block party that cordons off Cherry Street has been bringing communities together for a night.
The Antioch Baptist Church Block Party satisfied all of the senses as attendees heard the music even as they approached the event, saw the numerous tables for healthy living and politics, felt the bumpiness of a wagon drawn by horses and, of course, smelled and tasted numerous types of food.
And it was all free.
Article Photos
MARK NANCE/Sun-Gazette
Two youngsters take in the view as they take a horse-drawn wagon ride, provided by Peterman Farms, of Muncy Valley, during the Antioch Baptist Church annual block party on Wednesday.
MARK NANCE/Sun-Gazette
With a hot dog in one hand and a lollipop in the other, Madoka Charles, 2, daughter of Matthew and Mihono Charles, of Hughesville, is mesmerized by the music at the block party on Wednesday.
MARK NANCE/Sun-Gazette
Crowds pack Cherry Street for free food and entertainment during Antioch Baptist's annual block party on Wednesday.
MARK NANCE/Sun-Gazette
WAHS auto mechanics instructor Pat Dixon, left, and Principal Mike Reed grill hot dogs and sausages during the Antioch Baptist Church's annual block party on Wednesday.
MARK NANCE/Sun-Gazette
Thomas Edmond Whaley III, 5, son of Thomas Whaley Jr., of Williamsport, throws a wet ball at the target at The Big Splash game.
Lisa Adams, of Williamsport, comes every year with her family for a chance to mingle with people she has not seen in a while and to let her son enjoy himself on the rides.
"It gives the kids a chance to get out and run wild," Adams said. "It's always right before school starts. ... They know it's coming."
When she arrived Wednesday night, she said she saw a lot more people this year than she did the previous year.
She was with her 9-year-old niece, Lily, who planned to walk around but avoid the horse-drawn wagon and the horseback ride.
"I want to see my BFF," she said, referencing the acronym for "best friend forever."
While Lily may have been avoiding the horses, they still were popular, said Dorsey Littles, of Williamsport.
His task for the night was to help people take their places on the wagon ride, which went for a few blocks around the city. He estimated that by midway through the event, 300 people already had taken a ride in the wagon.
There was a mixture of kids and adults, with some adults wanting to ride with their children and others just wanting to enjoy it for themselves, he said.
The block party began 20 years ago as a way to bring different communities together to have good, clean fun, said Sam Washington, church pastor. Somebody needed to step up to show that people could come together to party in a constructive way.
Even though the church has had the event for two decades, it still takes an entire month to put everything together because it is has grown so much, he said.
Now it has grown so large that at least four churches participate in the event, bringing different kinds of food, such as Spanish and Italian dishes, to distribute to people for free.
The block party was about more than just food, though.
People danced in the grass as bands played and then danced on the stage when invited to join during popular songs, such as the Cupid Shuffle, where a large group of young and old people were told to move right and left and kick.
Games were set up so children could win prizes, such as candy and slap bracelets. Similar to a dunk tank, children could throw a wet ball at a target, which would dump a bucket of water on the person sitting on a chair. Children also could test their basketball and baseball skills at other games throughout the street.
Priscilla Davis, of Newberry, brought her children out to the block party for a fun night.
"It's enjoyable," she said. "It's great for the community. It brings the community together."


text:
21 years of experience
Accepting new patients
Video profile
1000 Harrington St
Mount Clemens, MI 48043 Phone number & directions
Video: Dr. Bryan Mazey, DO
Ophthalmologist (eyes) in Mount Clemens, MITake a minute to learn about Dr. Bryan Mazey in this video. If you'd like to learn more, click on one of the links below.
Meet Doctor Bryan J Mazey. Here are his vitals: He specializes in General Practice with expertise in several areas. He has 18 years experience. The average for this specialty is 24 years. Highly regarded by his patients they rate him 3 out of 4 stars. They point out his bedside manners. Is affiliated with these top rated hospitals. Graduated from A.T. Still University - Kirksville. His average waiting time is 29 minutes. He accepts new patients. He has a number of insurance plans accepted. Use Vitals.com to examine Doctor Bryan J Mazey from New Baltimore, Michigan. See patient comments make an appointment or even let us help you to prepare for your visit. Vitals .com where doctors are examined.


text:
Star Tracks: Monday, May 16, 2016 42 years, 2,191 covers and 55,436 stories from PEOPLE magazine's history for you to enjoy
Latest News!
- Donald Trump Had a Short Cameo in a 2000 Playboy 'Centerfold' Video
- Read the Cover Story: Brad & Angelina Split After 12 Years: It's Over
- Paris Jackson Enjoys PDA-Filled Vacation with Boyfriend Michael Snoddy
- Former Power Rangers Star Ricardo Medina Jr. Denies Killing His Roommate with a Sword
- Family Love! Tracee Ellis Ross Shares Cute Snapshot of Mom Diana Ross and Sisters
People Top 5
LAST UPDATE: Tuesday February 10, 2015 01:10PM EST
PEOPLE Top 5 are the most-viewed stories on the site over the past three days, updated every 60 minutes
- November 28, 1983
- Vol. 20
- No. 22
Let's see. If you add up just a few of David Bowie's 1983 credits, you get: a successful world concert tour, a chart-busting LP, Let's Dance, a multimillion-dollar record contract with EMI and a lead in the film Merry Christmas, Mr. Lawrence. Think it's gone to his head? No way. David recently ordered a custom-made T-shirt. On the front, it reads: "This year's grand fromage." On the back: "Next year's rind."
Mother, May I?
"This is the Victorian way, and I think I'll bring it back," said Brenda Vaccaro, who attended a party at L.A.'s Improv with an unusual date: her mom. "If I'd listened to my mother I wouldn't have married some of the men I married," added Brenda, recently split from her third husband. "Now I'm going to take her everywhere with me and listen to everything she tells me. If I ever consider getting involved again, I'm going to say, 'Mom, what do you think of him?' We argued over one man for four years. And guess what? She was right. I wish I had known she was so smart sooner."
Wardrobe Heeler
"I want to say I have absolutely no taste in clothes," Howard Baker confessed to the Senate in response to an announcement of this year's 10 best-dressed men by a group called the Tailors Council of America. Ronald Reagan won the top honors in Washington, but word had it that the casual Baker was a close runner-up. Though he responded to the rumor with humor, Howard might have laughed even harder if he had first spoken with Irma Lipkin, executive director of the well-established Custom Tailors and Designers Association of America. "Those awards are a crock, a PR stunt," says she. "As far as I know, we are the only tailoring organization in America." The other outfit's head, Beverly Hills tailor Jack Taylor (notice the last name), then tried to make everything perfectly clear. He said he presides over a very loose network of 120 to 125 tailors across the country, and he canvassed, oh, at least 40 of them over the phone to come up with his best-dressed list. As he tells it, about 20 of his friends swore Reagan in; only four or five voted for Baker. That's democracy for ya, but please, no recount.
Hush, Child
Tina Sinatra wants to raise money to produce a film about father/ daughter relationships called Home Sweet Home. Though she knew Ol' Blue Eyes wouldn't fork over any dough, she did get him to make one commitment: He'll star in the movie opposite JoBeth Williams, who will play his little girl. Says Tina, "Dad never worked for me before. We've agreed if this project goes through, we'll either be closer than ever or never speak to each other again."
Non-Talking Heads
If you think touring the Far East meant endless excitement for Ronald and Nancy Reagan, you obviously missed their banquet with Japan's Emperor Hirohito. That man of few words remained silent and shook hands while an aide greeted 142 arriving guests by repeating one line from a cue card ("I am glad you could come"). Sitting between the Reagans at dinner, the Emperor still barely spoke, though an interpreter stood behind him. Afterward, White House gossips report, the Reagans rated the imperial meal the single most boring state dinner they had ever attended.
•"It's vulgar to talk about money if your net worth is over $20 million," pronounced Broadway's La Cage aux Folles producer Alan Carr at a Beverly Hills dinner in his honor. Asked about his own financial status, Carr just adjusted his diamond Tiffany pin and purred, "No comment." Is he trying to tell us something?
•"There's a merger on the boards between Chrysler and De Lorean," joked retired United Auto Workers chief Douglas Fraser at a Washington bash, "Iacocca will be making the automobiles and De Lorean will be making the license plates."
More in the Archive
Today's Photos
Treat Yourself! 4 Preview Issues
The most buzzed about stars this minute!


text:
THE African National Congress (ANC) in KwaZulu-Natal would use the party's policy conference next week to call for a national convention on economic transformation and should be attended by all key stakeholders, the party's provincial secretary Sihle Zikalala said yesterday.
KwaZulu-Natal is the ruling party's biggest province in terms of signed up members. ANC discussion documents for next week's policy conference have called for urgent economic changes to address poverty, inequality and unemployment.
Mr Zikalala said at the conclusion of a two-day policy workshop in Durban yesterday that agreements reached at the proposed convention should be binding on all parties, "including the capitalist class", and the ANC should then embark on "radical" transformation.
Political analyst Protas Madlala said there was no doubt economic issues would be a focus at the policy conference, but he was sceptical about a convention of stakeholders, as these "tend to replace action".
Mr Zikalala said the ANC in KwaZulu-Natal did not want "classical nationalisation", but it supported intensified state influence in mining through taxation, royalties, a state mining company and acquisition of strategic assets. The proposed state company should be given preferences over private companies and over all aspects of the business such as for licences and land.
Mr Zikalala said the provincial party wanted the intelligentsia and middle classes to be mobilised, and not let them slip into the hands of the opposition, since they had knowledge required for transformation.
Mr Madlala said economic transformation so far had "made a mockery of democracy", was still a long way to go and the private sector was not yet fully on board.
Mr Zikalala said land redistribution should be accelerated and ANC resolutions that government should not sell prime land to foreigners should be adopted.
He said the ANC in KwaZulu-Natal also wanted the number of provinces to be rationalised.
On organisational renewal, he said the ANC in the province did not want to change the practice of drawing disciplinary committee members from the national executive committee (NEC).
The ANC in KwaZulu-Natal has previously proposed that the number of leaders on the ANC's NEC be reduced to 66 from 88. All ANC leaders who serve on committees should have been an ordinary member for at least five years, it suggested.
Mr Zikalala said the ANC in the province also wanted a ban on derogatory songs, slogans, T-shirts and heckling.


text:
The latest version of Adobe Flash Player is required to watch this video.
Please click on the link below to download the latest version. Thanks!
LONDON -- Landmark rulings on the cases of four Christian workers were decided Tuesday in The European Court of Human Rights, setting an historic precedent for religious freedom.
The court has ruled that the United Kingdom had failed to protect the freedom of a British Airways worker to wear her cross to work.
But they rejected the case of Christian nurse Shirley Chaplin, who was refused the right to wear her cross for health and safety reasons.
Is similar persecution coming to North America? Greg Musselman, with Voice of the Martyrs Canada, talks about this and much more, on Christian World News, Jan. 18.
Following the rulings, British Prime Minister David Cameron said he was "delighted" that the "principle of wearing religious symbols at work has been upheld," adding that people "shouldn't suffer discrimination due to religious beliefs."
However, Chaplin, whose case was supported by the Christian Legal Centre, said she's very disappointed that her religious principles hadn't been upheld.
Despite her case being rejected Chaplin said she was encouraged by the court's decision to acknowledge that the cross is a Christian symbol.
Two other cases of Christian workers were rejected by the European Court of Human Rights, including that of relationship counselor Gary McFarlane. He was sacked for saying he might not be comfortable giving sex counseling to homosexual couples.
McFarlane, who is also being supported by the Christian Legal Centre, said he's not disappointed by Tuesday's decision.
Meanwhile, the Christian Legal Centre's Andrea Williams said they won't give up on these cases.
As the legal group continues to fight for the rights of Christians to express their beliefs in the workplace, many believers remain deeply concerned that the European Court's ruling means these freedoms continue to hang in the balance.
UK Workers Fight Gov't Ban on Religious Symbols
Log in or create an account to post a comment.
Are you seeking answers in life? Are you hurting? Are you facing a difficult situation?
Find peace with God, discover more about God or send us your prayer request.
Call The 700 Club Prayer Center at 1 (800) 823-6053, 24 hours a day.
A caring friend will be there to pray with you in your time of need.
CBN News United Kingdom Correspondent
CBN News is a national/international, nonprofit news organization that provides programming by cable, satellite, and the Internet, 24-hours a day. Follow us on Facebook, Twitter, and Google+.


text:
Digital Storm Bolt Desktop Gaming PC Review
Final Thoughts
Let's take a look at what we've just seen in the benchmarks. The Digital Storm Bolt is just slightly larger than your everyday gaming console, yet its performance is many times higher. This system would be a great option for a HTPC and could easily replace your PlayStation 3 if configured with the optional Blu-ray drive.
While this system does offer fewer configuration options than others available, it does offer some unique advantages over those others. For one, the Bolt's case is a completely custom designed by Digital Storm.
While we're on the topic of a completely custom case, let's note that it doesn't have all of the fit and finish of the mass produced cases on the market. Don't get me wrong, it looks great and feels solid. However, I did run into some slight clearance issues when trying to open and close the case. It's not a massive problem as most people won't be going in and out of their case daily. It is worth noting that some slight tweaking of the side panel was required to get it to slide off. Other than that, the custom case is awesome.
Users who place their system on their desk will also benefit from the small footprint presented by this pint-sized machine. They will not have to sacrifice performance in order to reclaim their desk space. As the owner of a PC in a giant CoolerMaster HAF 932, I know this fact all too well. It will also be easy to move around, which is especially good if you are someone who enjoys LAN parties.
Our review system came with an NVIDIA 660 Ti, which isn't the fastest video card around. However, the system can be customized with an NVIDIA 680, GTX Titan or upgraded at a later time as money and needs dictate.
But now we need to bring the price into the discussion. Coming in at $1,599, I would have liked to see the system come with a slightly better video card. Toss in a GTX 670 into this machine and Digital Storm has themselves a real winner on their hands. With the current 660 Ti, I'm not as sure I could justify $1,600.
If we add in the customer support, cable management, and incredible form factor that Digital Storm has achieved, the price starts to become a bit easier to swallow. All-in-all, the Digital Storm Bolt feels like a solid, quality machine. It managed to survive our benchmarks, which isn't an easy task.
Next time you're in the market for a new small form-factor desktop, the Bolt should definitely be on your list of systems to take a look at. Ultimately you'll need to see if the somewhat limited configuration options allow you the flexibility you require.
PRICING: You can find products similar to this one for sale below.
United States: Find other tech and computer products like this over at Amazon's website.
United Kingdom: Find other tech and computer products like this over at Amazon UK's website.
Canada: Find other tech and computer products like this over at Amazon Canada's website.
Recommended for You
- We at TweakTown openly invite the companies who provide us with review samples / who are mentioned or discussed to express their opinion of our content. If any company representative wishes to respond, we will publish the response here.
Related Tags
Latest News Posts
- How you can become a hacker's worst nightmare
- Snapchat announces sunglasses with a built-in camera
- How to build dynamic web apps with Angular JS
- Samsung Galaxy S8 rumored to rock a 4K display
- Google rumored to acquire Twitter, news to break soon
Forum Activity
- Prepping LGA2011 Build
- Unable to find BIOS update for motherboard
- Lian Li O Series Multiple Expansion card support
- asrock fatality h170 performance red light on bios and not monitor output no beeps
- Anidees AI Crystal Mid-Tower Chassis Review
Press Releases
- Antec and Razer team up to co-brand a new Mini-ITX gaming chassis
- Samsung Electronics accelerates the NVMe era for consumers with its highest performing 960 PRO and EVO Solid State Drives
- Lighting is in the Aer: NZXT launches Aer RGB, premium LED PWM fans
- Syber Gaming delivers VR and 4K-ready 'C Series' small form factor gaming PC
- HyperX Gears of War gaming headset shipping now


text:
Meet hot Greenlawn lesbian personals at matchmaker personals. Our site has thousands of lesbian, gay women, bisexual, transgender and transsexual members. Looking for a same sex relationships and looking for women seeking women in Greenlawn then create a free profile today, it's easy!
GreenlawnJoin Now Free!
Greenlawn | Greenlawn Girls | Greenlawn Men | Greenlawn Gay
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Black Singles | Asian Singles | Latin Dating
Matchmaker is a free Greenlawn lesbian personals site for your local area. We have the hottest, attractive and available Greenlawn lesbian women on the Internet If you are a single lesbian women in Greenlawn and are looking for friendship, casual encounters or a serious relationship, create your free profile today!